LOCUS       DAYYEF010000001       132617 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000001 DAYYEF010000000
VERSION     DAYYEF010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 132617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 132617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..132617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.001"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(33..1076)
                     /locus_tag="ACHA1B_000001"
     CDS             complement(33..1076)
                     /locus_tag="ACHA1B_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM8700808.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
     gene            complement(1237..1920)
                     /locus_tag="ACHA1B_000002"
     CDS             complement(1237..1920)
                     /locus_tag="ACHA1B_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HFM8700809.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            2115..3044
                     /locus_tag="ACHA1B_000003"
     CDS             2115..3044
                     /locus_tag="ACHA1B_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HFM8700810.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            3105..3896
                     /gene="phnC"
                     /locus_tag="ACHA1B_000004"
     CDS             3105..3896
                     /gene="phnC"
                     /locus_tag="ACHA1B_000004"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HFM8700811.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            3868..4647
                     /gene="phnE"
                     /locus_tag="ACHA1B_000005"
     CDS             3868..4647
                     /gene="phnE"
                     /locus_tag="ACHA1B_000005"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HFM8700812.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            4644..5426
                     /gene="phnE"
                     /locus_tag="ACHA1B_000006"
     CDS             4644..5426
                     /gene="phnE"
                     /locus_tag="ACHA1B_000006"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015416 - ABC-type phosphonate transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015716 - organic phosphonate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HFM8700813.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            5429..6232
                     /locus_tag="ACHA1B_000007"
     CDS             5429..6232
                     /locus_tag="ACHA1B_000007"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFM8700814.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            6316..7863
                     /locus_tag="ACHA1B_000008"
     CDS             6316..7863
                     /locus_tag="ACHA1B_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HFM8700815.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(8160..8357)
                     /locus_tag="ACHA1B_000009"
     CDS             complement(8160..8357)
                     /locus_tag="ACHA1B_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700816.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(8433..8633)
                     /locus_tag="ACHA1B_000010"
     CDS             complement(8433..8633)
                     /locus_tag="ACHA1B_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFM8700817.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            complement(8753..9940)
                     /locus_tag="ACHA1B_000011"
                     /pseudo
     CDS             complement(8753..9940)
                     /locus_tag="ACHA1B_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9985..11111)
                     /locus_tag="ACHA1B_000012"
     CDS             complement(join(9985..10883,10883..11111))
                     /locus_tag="ACHA1B_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFM8700818.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(11515..12297)
                     /locus_tag="ACHA1B_000013"
     CDS             complement(11515..12297)
                     /locus_tag="ACHA1B_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700819.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(12362..13198)
                     /locus_tag="ACHA1B_000014"
     CDS             complement(12362..13198)
                     /locus_tag="ACHA1B_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFM8700820.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(13216..14625)
                     /locus_tag="ACHA1B_000015"
     CDS             complement(13216..14625)
                     /locus_tag="ACHA1B_000015"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFM8700821.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(14639..16462)
                     /locus_tag="ACHA1B_000016"
     CDS             complement(14639..16462)
                     /locus_tag="ACHA1B_000016"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFM8700822.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(17305..17631)
                     /locus_tag="ACHA1B_000017"
     CDS             complement(17305..17631)
                     /locus_tag="ACHA1B_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700823.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(17677..18039)
                     /locus_tag="ACHA1B_000018"
     CDS             complement(17677..18039)
                     /locus_tag="ACHA1B_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HFM8700824.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(18076..18290)
                     /locus_tag="ACHA1B_000019"
                     /pseudo
     CDS             complement(18076..18290)
                     /locus_tag="ACHA1B_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            18418..18753
                     /locus_tag="ACHA1B_000020"
     CDS             18418..18753
                     /locus_tag="ACHA1B_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8700825.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(18829..20826)
                     /locus_tag="ACHA1B_000021"
     CDS             complement(18829..20826)
                     /locus_tag="ACHA1B_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700826.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(20924..21199)
                     /locus_tag="ACHA1B_000022"
     CDS             complement(20924..21199)
                     /locus_tag="ACHA1B_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8700827.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            21431..22165
                     /locus_tag="ACHA1B_000023"
     CDS             21431..22165
                     /locus_tag="ACHA1B_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8700828.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            22204..23346
                     /locus_tag="ACHA1B_000024"
     CDS             22204..23346
                     /locus_tag="ACHA1B_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8700829.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(23441..24832)
                     /gene="sufB"
                     /locus_tag="ACHA1B_000025"
     CDS             complement(23441..24832)
                     /gene="sufB"
                     /locus_tag="ACHA1B_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HFM8700830.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(24837..25307)
                     /gene="sufU"
                     /locus_tag="ACHA1B_000026"
     CDS             complement(24837..25307)
                     /gene="sufU"
                     /locus_tag="ACHA1B_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="HFM8700831.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(25294..26529)
                     /locus_tag="ACHA1B_000027"
     CDS             complement(25294..26529)
                     /locus_tag="ACHA1B_000027"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0031071 - cysteine desulfurase activity
                     [Evidence IEA];
                     GO_process: GO:0006534 - cysteine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HFM8700832.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(26526..27812)
                     /gene="sufD"
                     /locus_tag="ACHA1B_000028"
     CDS             complement(26526..27812)
                     /gene="sufD"
                     /locus_tag="ACHA1B_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HFM8700833.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(27825..28598)
                     /gene="sufC"
                     /locus_tag="ACHA1B_000029"
     CDS             complement(27825..28598)
                     /gene="sufC"
                     /locus_tag="ACHA1B_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HFM8700834.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(28795..29643)
                     /locus_tag="ACHA1B_000030"
     CDS             complement(28795..29643)
                     /locus_tag="ACHA1B_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFM8700835.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(29667..30353)
                     /locus_tag="ACHA1B_000031"
     CDS             complement(29667..30353)
                     /locus_tag="ACHA1B_000031"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFM8700836.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(30346..31380)
                     /locus_tag="ACHA1B_000032"
     CDS             complement(30346..31380)
                     /locus_tag="ACHA1B_000032"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFM8700837.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(31443..31699)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(31775..32113)
                     /locus_tag="ACHA1B_000033"
     CDS             complement(31775..32113)
                     /locus_tag="ACHA1B_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HFM8700838.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(32115..32471)
                     /locus_tag="ACHA1B_000034"
     CDS             complement(32115..32471)
                     /locus_tag="ACHA1B_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HFM8700839.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(32477..33664)
                     /locus_tag="ACHA1B_000035"
     CDS             complement(32477..33664)
                     /locus_tag="ACHA1B_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFM8700840.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(33855..34700)
                     /locus_tag="ACHA1B_000036"
     CDS             complement(33855..34700)
                     /locus_tag="ACHA1B_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFM8700841.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            34934..35899
                     /locus_tag="ACHA1B_000037"
     CDS             34934..35899
                     /locus_tag="ACHA1B_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HFM8700842.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            36276..37319
                     /locus_tag="ACHA1B_000038"
     CDS             36276..37319
                     /locus_tag="ACHA1B_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HFM8700843.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(37381..37845)
                     /locus_tag="ACHA1B_000039"
     CDS             complement(37381..37845)
                     /locus_tag="ACHA1B_000039"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003908 -
                     methylated-DNA-[protein]-cysteine S-methyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HFM8700844.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            38091..39038
                     /locus_tag="ACHA1B_000040"
     CDS             38091..39038
                     /locus_tag="ACHA1B_000040"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM8700845.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(39249..41321)
                     /locus_tag="ACHA1B_000041"
     CDS             complement(39249..41321)
                     /locus_tag="ACHA1B_000041"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_function: GO:0098847 - sequence-specific single
                     stranded DNA binding [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0051304 - chromosome separation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFM8700846.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(41254..41631)
                     /locus_tag="ACHA1B_000042"
     CDS             complement(41254..41631)
                     /locus_tag="ACHA1B_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HFM8700847.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(41760..42320)
                     /locus_tag="ACHA1B_000043"
     CDS             complement(41760..42320)
                     /locus_tag="ACHA1B_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8700848.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            42470..43762
                     /locus_tag="ACHA1B_000044"
     CDS             42470..43762
                     /locus_tag="ACHA1B_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFM8700849.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(43822..44940)
                     /locus_tag="ACHA1B_000045"
     CDS             complement(43822..44940)
                     /locus_tag="ACHA1B_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HFM8700850.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(44954..46375)
                     /gene="arcD"
                     /locus_tag="ACHA1B_000046"
     CDS             complement(44954..46375)
                     /gene="arcD"
                     /locus_tag="ACHA1B_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0043858 - arginine:ornithine antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006527 - arginine catabolic process
                     [Evidence IEA];
                     GO_process: GO:1903826 - L-arginine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HFM8700851.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(46621..47742)
                     /gene="mnmA"
                     /locus_tag="ACHA1B_000047"
     CDS             complement(46621..47742)
                     /gene="mnmA"
                     /locus_tag="ACHA1B_000047"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016783 - sulfurtransferase activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HFM8700852.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            48146..48745
                     /locus_tag="ACHA1B_000048"
     CDS             48146..48745
                     /locus_tag="ACHA1B_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFM8700853.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(48883..50169)
                     /gene="efmA"
                     /locus_tag="ACHA1B_000049"
     CDS             complement(48883..50169)
                     /gene="efmA"
                     /locus_tag="ACHA1B_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HFM8700854.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(50440..50784)
                     /locus_tag="ACHA1B_000050"
     CDS             complement(50440..50784)
                     /locus_tag="ACHA1B_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HFM8700855.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(50921..52066)
                     /locus_tag="ACHA1B_000051"
     CDS             complement(50921..52066)
                     /locus_tag="ACHA1B_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFM8700856.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(52246..53220)
                     /locus_tag="ACHA1B_000052"
     CDS             complement(52246..53220)
                     /locus_tag="ACHA1B_000052"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFM8700857.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(53300..54175)
                     /locus_tag="ACHA1B_000053"
     CDS             complement(53300..54175)
                     /locus_tag="ACHA1B_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HFM8700858.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            54305..56212
                     /locus_tag="ACHA1B_000054"
     CDS             54305..56212
                     /locus_tag="ACHA1B_000054"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M13-type metalloendopeptidase"
                     /protein_id="HFM8700859.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(56753..60031)
                     /locus_tag="ACHA1B_000055"
     CDS             complement(56753..60031)
                     /locus_tag="ACHA1B_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="HFM8700860.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(60302..60847)
                     /locus_tag="ACHA1B_000056"
     CDS             complement(60302..60847)
                     /locus_tag="ACHA1B_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFM8700861.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(60859..61551)
                     /locus_tag="ACHA1B_000057"
     CDS             complement(60859..61551)
                     /locus_tag="ACHA1B_000057"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008782 - adenosylhomocysteine
                     nucleosidase activity [Evidence IEA];
                     GO_function: GO:0008930 - methylthioadenosine nucleosidase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009164 - nucleoside catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019509 - L-methionine salvage from
                     methylthioadenosine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HFM8700862.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(61570..61854)
                     /gene="macP"
                     /locus_tag="ACHA1B_000058"
     CDS             complement(61570..61854)
                     /gene="macP"
                     /locus_tag="ACHA1B_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall synthase accessory phosphoprotein
                     MacP"
                     /protein_id="HFM8700863.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(61867..62430)
                     /locus_tag="ACHA1B_000059"
     CDS             complement(61867..62430)
                     /locus_tag="ACHA1B_000059"
                     /EC_number="3.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFM8700864.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            62658..63320
                     /locus_tag="ACHA1B_000060"
     CDS             62658..63320
                     /locus_tag="ACHA1B_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HFM8700865.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            63444..64640
                     /locus_tag="ACHA1B_000061"
     CDS             63444..64640
                     /locus_tag="ACHA1B_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HFM8700866.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(64741..66117)
                     /locus_tag="ACHA1B_000062"
     CDS             complement(64741..66117)
                     /locus_tag="ACHA1B_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFM8700867.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(66154..67020)
                     /locus_tag="ACHA1B_000063"
     CDS             complement(66154..67020)
                     /locus_tag="ACHA1B_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFM8700868.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(67109..68134)
                     /locus_tag="ACHA1B_000064"
     CDS             complement(67109..68134)
                     /locus_tag="ACHA1B_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFM8700869.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(68152..68826)
                     /locus_tag="ACHA1B_000065"
     CDS             complement(68152..68826)
                     /locus_tag="ACHA1B_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM8700870.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(69010..69903)
                     /locus_tag="ACHA1B_000066"
     CDS             complement(69010..69903)
                     /locus_tag="ACHA1B_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFM8700871.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(69977..71674)
                     /locus_tag="ACHA1B_000067"
     CDS             complement(69977..71674)
                     /locus_tag="ACHA1B_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFM8700872.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(71667..72979)
                     /locus_tag="ACHA1B_000068"
                     /pseudo
     CDS             complement(71667..72979)
                     /locus_tag="ACHA1B_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
     gene            complement(72979..76920)
                     /locus_tag="ACHA1B_000069"
     CDS             complement(72979..76920)
                     /locus_tag="ACHA1B_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFM8700873.1"
                     /translation="MEKLDEPIVPSGQALQRIQRQLFNGILERLGPTATQDPYEYIYP
                     SGEVENEQHRYPKFTTNDYTKVLGNWTQSNERYQGDKGSPYDGENLIDDSDYTNGGAN
                     WRNYDYATNNGSTAGEEDRNVPAQTVQLWGNERNFENSYLDYNGAYIKKWVEPVLPSS
                     TASDLHPEDATTLYNVYLDVIGGEKKEISPIDIVFVLDKSASMSELTAGTNSQTKNAA
                     LIEAVNEMSKDLLSDPSLDIRIGMVNFYHNSTAINNHEQISSDIFPLTNDINRLTGSE
                     NTALNRTPIGGTPLTLGLKNGYETLYKDNGGENRNPEKILIVVGDGTPTFSYAPIQSS
                     YRTSTNGAWSNWTVMEDKIAEDNDVLFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDE
                     VNVHYRYGEVKEGDNKATHWVGDGSSNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQE
                     NPPSIFSIGLGIDGNVSGRQRLDAIGRNVLKNIADLEEDGVTPRYYNANNKNDIVTAL
                     EDISSTFKRTIQQATLYDETGFNVSPFGAGRSADIQFYHLDPGENGMKYQEPEIWDEE
                     RHGQAPPEVVATPTTYVGRENQAYKFSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVN
                     NMAYIQNLEDYENDITTGRMYFPSSSIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQ
                     NPESGEAEPIETSKTTTDGIAIFETKMPILGDETGAVSDIFWIREIAGPPRYQLVDET
                     YQFQIKKYAANEDEMLGHYELVDEYTSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNI
                     EGTEYDELYVKLEMRNEFKPIHMNINKLIEGSNMPINGAEFELYETDGNGLEIGYPVA
                     KGLSGVNEVEEEKGRLTFYSVDEDGKYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAE
                     YKIIESQNPEGFKEPDENDTWILRLYDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWV
                     AFTAYNTFDYREIRVRKLDHEGHTLDGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKR
                     LPGIGYFYSRAVGVEKYVDLNYDQPLHLSIGEYEVSESVAPNGYRLSDQVFQFALNEE
                     GKFIIEDTVIEDETAPLPEGYEIIDGVLQVTLEDELAPIDLELLKIDSMNSRRLEGAE
                     FSIEKQNSAGEYEIIEGGLAPDPNDSSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFI
                     LEISYREEPDIENDRVVPGKEAGTLKVEISYYPNEEAETPDLQQELEYELLETNRIRL
                     QLSVGNDPENPLPATGGSGRLFYILLAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(77029..77487)
                     /locus_tag="ACHA1B_000070"
     CDS             complement(77029..77487)
                     /locus_tag="ACHA1B_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFM8700874.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(77785..78303)
                     /locus_tag="ACHA1B_000071"
     CDS             complement(77785..78303)
                     /locus_tag="ACHA1B_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFM8700875.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(78305..78922)
                     /locus_tag="ACHA1B_000072"
     CDS             complement(78305..78922)
                     /locus_tag="ACHA1B_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFM8700876.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(78919..79773)
                     /locus_tag="ACHA1B_000073"
     CDS             complement(78919..79773)
                     /locus_tag="ACHA1B_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8700877.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(79770..80681)
                     /locus_tag="ACHA1B_000074"
     CDS             complement(79770..80681)
                     /locus_tag="ACHA1B_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8700878.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(80722..82056)
                     /locus_tag="ACHA1B_000075"
     CDS             complement(80722..82056)
                     /locus_tag="ACHA1B_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8700879.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            82264..83094
                     /locus_tag="ACHA1B_000076"
     CDS             82264..83094
                     /locus_tag="ACHA1B_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HFM8700880.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(83338..83587)
                     /locus_tag="ACHA1B_000077"
                     /pseudo
     CDS             complement(83338..83587)
                     /locus_tag="ACHA1B_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(83778..83972)
                     /locus_tag="ACHA1B_000078"
     CDS             complement(83778..83972)
                     /locus_tag="ACHA1B_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700881.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(84477..84662)
                     /locus_tag="ACHA1B_000079"
     CDS             complement(84477..84662)
                     /locus_tag="ACHA1B_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700882.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(85512..85853)
                     /locus_tag="ACHA1B_000080"
     CDS             complement(85512..85853)
                     /locus_tag="ACHA1B_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFM8700883.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(85853..86083)
                     /locus_tag="ACHA1B_000081"
     CDS             complement(85853..86083)
                     /locus_tag="ACHA1B_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFM8700884.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            86370..86708
                     /locus_tag="ACHA1B_000082"
     CDS             86370..86708
                     /locus_tag="ACHA1B_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700885.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(86913..87475)
                     /locus_tag="ACHA1B_000083"
                     /pseudo
     CDS             complement(86913..87475)
                     /locus_tag="ACHA1B_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
     gene            complement(88207..88788)
                     /locus_tag="ACHA1B_000084"
     CDS             complement(88207..88788)
                     /locus_tag="ACHA1B_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8700886.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(88971..89597)
                     /locus_tag="ACHA1B_000085"
     CDS             complement(88971..89597)
                     /locus_tag="ACHA1B_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFM8700887.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(89619..90950)
                     /locus_tag="ACHA1B_000086"
     CDS             complement(89619..90950)
                     /locus_tag="ACHA1B_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HFM8700888.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(91105..91506)
                     /locus_tag="ACHA1B_000087"
     CDS             complement(91105..91506)
                     /locus_tag="ACHA1B_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFM8700889.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(91592..91798)
                     /locus_tag="ACHA1B_000088"
     CDS             complement(91592..91798)
                     /locus_tag="ACHA1B_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700890.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(91893..93395)
                     /locus_tag="ACHA1B_000089"
     CDS             complement(91893..93395)
                     /locus_tag="ACHA1B_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HFM8700891.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(93413..93868)
                     /gene="argR"
                     /locus_tag="ACHA1B_000090"
     CDS             complement(93413..93868)
                     /gene="argR"
                     /locus_tag="ACHA1B_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006525 - arginine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFM8700892.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(93966..94583)
                     /locus_tag="ACHA1B_000091"
     CDS             complement(93966..94583)
                     /locus_tag="ACHA1B_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFM8700893.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            94804..96177
                     /locus_tag="ACHA1B_000092"
     CDS             94804..96177
                     /locus_tag="ACHA1B_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM8700894.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            96252..97364
                     /locus_tag="ACHA1B_000093"
     CDS             96252..97364
                     /locus_tag="ACHA1B_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFM8700895.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(97436..99073)
                     /locus_tag="ACHA1B_000094"
     CDS             complement(97436..99073)
                     /locus_tag="ACHA1B_000094"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004612 - phosphoenolpyruvate
                     carboxykinase (ATP) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HFM8700896.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(99241..99849)
                     /locus_tag="ACHA1B_000095"
     CDS             complement(99241..99849)
                     /locus_tag="ACHA1B_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFM8700897.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(100233..101384)
                     /gene="queG"
                     /locus_tag="ACHA1B_000096"
     CDS             complement(100233..101384)
                     /gene="queG"
                     /locus_tag="ACHA1B_000096"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0052693 - epoxyqueuosine reductase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA];
                     GO_process: GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HFM8700898.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(101403..102155)
                     /locus_tag="ACHA1B_000097"
     CDS             complement(101403..102155)
                     /locus_tag="ACHA1B_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700899.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(102296..103245)
                     /locus_tag="ACHA1B_000098"
                     /pseudo
     CDS             complement(102296..103245)
                     /locus_tag="ACHA1B_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
     gene            complement(103246..104085)
                     /locus_tag="ACHA1B_000099"
     CDS             complement(103246..104085)
                     /locus_tag="ACHA1B_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFM8700900.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(104082..104828)
                     /locus_tag="ACHA1B_000100"
     CDS             complement(104082..104828)
                     /locus_tag="ACHA1B_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFM8700901.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            105066..106436
                     /locus_tag="ACHA1B_000101"
     CDS             105066..106436
                     /locus_tag="ACHA1B_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFM8700902.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(106491..107387)
                     /locus_tag="ACHA1B_000102"
     CDS             complement(106491..107387)
                     /locus_tag="ACHA1B_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFM8700903.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(107501..107671)
                     /locus_tag="ACHA1B_000103"
     CDS             complement(107501..107671)
                     /locus_tag="ACHA1B_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700904.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(107668..108345)
                     /locus_tag="ACHA1B_000104"
     CDS             complement(107668..108345)
                     /locus_tag="ACHA1B_000104"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0050136 - NADH:ubiquinone reductase
                     (non-electrogenic) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFM8700905.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(108436..109341)
                     /locus_tag="ACHA1B_000105"
     CDS             complement(108436..109341)
                     /locus_tag="ACHA1B_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HFM8700906.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            109516..110940
                     /locus_tag="ACHA1B_000106"
     CDS             109516..110940
                     /locus_tag="ACHA1B_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015486 -
                     glycoside-pentoside-hexuronide:cation symporter activity
                     [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide (GPH):cation
                     symporter"
                     /protein_id="HFM8700907.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            110986..112017
                     /locus_tag="ACHA1B_000107"
     CDS             110986..112017
                     /locus_tag="ACHA1B_000107"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFM8700908.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            112024..113211
                     /locus_tag="ACHA1B_000108"
     CDS             112024..113211
                     /locus_tag="ACHA1B_000108"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004335 - galactokinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0046835 - carbohydrate phosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HFM8700909.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            113367..114749
                     /locus_tag="ACHA1B_000109"
     CDS             113367..114749
                     /locus_tag="ACHA1B_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFM8700910.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            114786..115106
                     /locus_tag="ACHA1B_000110"
     CDS             114786..115106
                     /locus_tag="ACHA1B_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700911.1"
                     /translation="MGDCFCDGRTSQRYQKNEEEARKQPLPKQQMTLQEIDSILTEAF
                     LSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYFMIDHQPILWEDVRYIELKETKK
                     WFVT"
     gene            complement(115306..115974)
                     /locus_tag="ACHA1B_000111"
     CDS             complement(115306..115974)
                     /locus_tag="ACHA1B_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HFM8700912.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(116163..116960)
                     /locus_tag="ACHA1B_000112"
                     /pseudo
     CDS             complement(116163..116960)
                     /locus_tag="ACHA1B_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(117241..118620)
                     /locus_tag="ACHA1B_000113"
     CDS             complement(117241..118620)
                     /locus_tag="ACHA1B_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFM8700913.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(118795..119964)
                     /locus_tag="ACHA1B_000114"
     CDS             complement(118795..119964)
                     /locus_tag="ACHA1B_000114"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFM8700914.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(119939..121090)
                     /locus_tag="ACHA1B_000115"
     CDS             complement(119939..121090)
                     /locus_tag="ACHA1B_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFM8700915.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(121050..122411)
                     /locus_tag="ACHA1B_000116"
     CDS             complement(121050..122411)
                     /locus_tag="ACHA1B_000116"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004072 - aspartate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HFM8700916.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(122408..123409)
                     /locus_tag="ACHA1B_000117"
     CDS             complement(122408..123409)
                     /locus_tag="ACHA1B_000117"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HFM8700917.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(123425..124120)
                     /gene="dapD"
                     /locus_tag="ACHA1B_000118"
     CDS             complement(123425..124120)
                     /gene="dapD"
                     /locus_tag="ACHA1B_000118"
                     /EC_number="2.3.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047200 - tetrahydrodipicolinate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HFM8700918.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(124126..124842)
                     /gene="dapB"
                     /locus_tag="ACHA1B_000119"
     CDS             complement(124126..124842)
                     /gene="dapB"
                     /locus_tag="ACHA1B_000119"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008839 - 4-hydroxy-tetrahydrodipicolinate
                     reductase [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HFM8700919.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(124839..125720)
                     /gene="dapA"
                     /locus_tag="ACHA1B_000120"
     CDS             complement(124839..125720)
                     /gene="dapA"
                     /locus_tag="ACHA1B_000120"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HFM8700920.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(125723..126523)
                     /gene="dapF"
                     /locus_tag="ACHA1B_000121"
     CDS             complement(125723..126523)
                     /gene="dapF"
                     /locus_tag="ACHA1B_000121"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HFM8700921.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(126510..127769)
                     /gene="lysA"
                     /locus_tag="ACHA1B_000122"
     CDS             complement(126510..127769)
                     /gene="lysA"
                     /locus_tag="ACHA1B_000122"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008836 - diaminopimelate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HFM8700922.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            complement(127984..128154)
                     /locus_tag="ACHA1B_000123"
     CDS             complement(127984..128154)
                     /locus_tag="ACHA1B_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700923.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            complement(128255..128818)
                     /gene="efp"
                     /locus_tag="ACHA1B_000124"
     CDS             complement(128255..128818)
                     /gene="efp"
                     /locus_tag="ACHA1B_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HFM8700924.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            129246..130163
                     /locus_tag="ACHA1B_000125"
     CDS             129246..130163
                     /locus_tag="ACHA1B_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HFM8700925.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            130176..131321
                     /locus_tag="ACHA1B_000126"
     CDS             130176..131321
                     /locus_tag="ACHA1B_000126"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HFM8700926.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            131492..131950
                     /locus_tag="ACHA1B_000127"
     CDS             131492..131950
                     /locus_tag="ACHA1B_000127"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0043768 - S-ribosylhomocysteine lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HFM8700927.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            132109..132579
                     /locus_tag="ACHA1B_000128"
     CDS             132109..132579
                     /locus_tag="ACHA1B_000128"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA];
                     GO_function: GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HFM8700928.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT        38101 a        27678 c        23700 g        43138 t
ORIGIN      
        1 actgtagaca tcatccataa aatggacttt gtctacagtc tgaaatcacc actgatgatt
       61 ttctcttttg cgtctgaaac tgcctgatag gcttcctctg ataattgtcc ttttgtcaga
      121 tctacccctt cttctttcaa accaaaggtc aaatgcttgc cgccaggaaa tttatcgtta
      181 tgagaagttt ctgcaaattc tttgacttct gcaccgacat ttttctttgt agaagtcaac
      241 gtgaaattcc ctgtctcgcc gttctccatt ttataatccc cttcatccgc ttgatcgcga
      301 tctacaccaa tcacccatac ttttctgcta tagtcgtttt cattgcgggc ttttgcttct
      361 tggaacaccc cagctccagt acttcctgcc gcctgataaa gaatatcgac tccctctttg
      421 tacatagaag cagcaatagc ttttccttta tctagcgaat cataggatgc agcatattgt
      481 acgttaacag taatttcctt gttcagtgct gtggcccctg ccttaacgcc agcttcaaat
      541 ccgctttgga aacgttggat cacgggccct tccattccac caataaagcc tacttgatca
      601 ctttttgtcg tatatgcggc agctagtcct gctaaatacg cactttcttg atctttaaag
      661 gttgctgatg agatattctt tttcccagta atctcaccat ctaccaaggc aaatttcaac
      721 tttggattat ctttagcagc attttccagt tcctctgctt gcaagtagct caagctaata
      781 atggtggtaa agccgtttct gattgcctga tcgatattgg tactgttatc ctctggattg
      841 ttcgtttcta tatacgtaaa atcttttttt gctgtcagct ttttctcttt tccccaagcc
      901 tctaatcctt cccagccagc ttgattgaag gagcggtcat caaccccgcc aaatccaaga
      961 accaaagcga ttttactttt ctctttttca ctttgcttct ccccctgaga ctgactacag
     1021 ccgactaacg ttactaatga caccaaaaac aacaatgaaa caagtatttt cttcaaaatt
     1081 tttctcccct ttttatgtgt cttgacacat tgaactttta aaagtatagc ataccaatat
     1141 atagaacact actcttcaac gaagattttc cgtttcccaa tttctccact atcaaaaaac
     1201 cagcaatcac ttctgactgc tgttttttta tagctgttat tctgctttta ctggactact
     1261 tatattctca gctaagtcct ctaaagcttc gatatcatga atcaagtaat aattcttttt
     1321 cttttcgata atattctcct cacgaaaatt cgtgattgtt cgtaaaagat gtcgataact
     1381 gacatttaag attgaggcgc aggtggttaa ccgaaatgag aaacgttcgt tttcgtgatg
     1441 ggtcaaaata aactttgcta aacgagtttc aacaggttct gtcagtgagt tcgccaaatt
     1501 tatcccggaa tttaaacgat aacttagtaa ctggcaaata ttctgcaaaa agcgaacatc
     1561 tttttgaagc tgtgttcgat attgatttag cggaatgctg atacagatgc acttagtcac
     1621 tgctttaacg ctgcttttcg gcgataattc ccacaatgaa gaggcttcgc cgagtggtgt
     1681 agcgggcttt gcgtaatcga tgcaaatatt ttgtgtatca gaagaatacg agtacaccat
     1741 taccgtccca tccactaaaa aatacaaata atctgaggtt tttcccgttt gaatgaggtg
     1801 ctcttccttt tcaaaaaaaa gtaaagaagc cattgccaat atatctgaat ccatataatc
     1861 ctgcaggttg tgcttctcaa cgtaagcagt taattgcttc gtatcatgga tttttttcat
     1921 gaaatcgtca cctctaagaa gtttttcttt attatagctt agattgtttt tcggctcaat
     1981 acgaataatt atttataatt gtttgtaaat tgtatgtaaa agttgtgtaa aataggacgt
     2041 gcgtcacttc attgattttg attccctgct atgatttaga cgtattagaa attatatcca
     2101 acaggaggag aaaaatgcag ttcaaacagt tagcaaaagg gttcatcgga gtcatgttat
     2161 tgaccacttt ggcggcctgc ggttctggga atacaagtag cagctcagaa aaagagagca
     2221 aagaaaaatt agttgttcaa ttcgttccaa caaacaatga tggtagtatg gaggcaaaag
     2281 caaaaccatt tgctaagtat ttatcgaaaa agttagatcg tgaggtagaa gtgacgttag
     2341 ctactgatta ttcaacgatc gtcgaagcga tgtcttctgg tcaagtcgat gtcggaatta
     2401 tgccgcctgc agcctatgtt caagcaaagg atgctggagc tgcagatgca atcctgactt
     2461 ctcagctcgg cgattatgat caagaaactg gcttgccatt aaaggacaaa cttacgaaca
     2521 cctttaaagg agaagtattg gttcgtgccg atagcggatt gaataagtta actgatttaa
     2581 aaggaaaaaa tatcgcaacc ttaagtccta actctgctag cggctacatc tatcctgtcg
     2641 ctgaattgaa agatgctggg attgatccta ctgcagatac aaagatgacc actgtgaatg
     2701 atattccgag tgagattacc gcagtgttga acaagcaaat ggatgcggcg tttgtttttg
     2761 aaggcgcgcg aaatgttttt gcttcgaatt tcccagataa tgatttattt aaggatttaa
     2821 aagtcctgta cctgacaaaa ggcgatattc cgaatgacgc aatcgctgta cagcctgaca
     2881 tgtcaaaaga tttaaaagcg aaaattaaag agaccttctt aaatatgaag gatgataaag
     2941 atggcaaaga agcaatggct ttgtgggggc atcagggcta tgaagaagct gctgattctg
     3001 cctatgacac gatcagagac tacacgaaaa aagcagcaga ataaaacatc agtaagtgtc
     3061 agcaagcttt tttttgctta cacttaaaaa aatggagaag gataatgatt atttttgaca
     3121 atgtttcgaa ggtctatccc aatggcgttg ttggcttgaa ggatattgac ttaacaattg
     3181 aagatggaga atttgtttcc atcatagggt tgagtggtgc tggaaagagc actctgctgc
     3241 gcagtatcaa tcgcttggca gaaaccacca aaggagatat tcgcattaat ggaacctcta
     3301 ttacaaaagc gaataaaaaa gagctgcgac agattcgccg ccagattggt ctaatctcgc
     3361 aaagcttcaa tctggtaaag cgtagtacgg ttcagaaaaa tgtgctatct ggacgtttgg
     3421 gctattactc cacttggaaa agtattttag gtctttttac gaaggaagac taccagcaga
     3481 caaaggaagc actggaaaaa gttggtttgt ctgataaatt gcagacacgc agtgatgagc
     3541 tcagtggtgg gcaacaacag cgagtatcca ttgcgcgagc actcgtgcag caagccccca
     3601 ttattttagc ggatgaaccc gttgcatcat tagatccaat cacgactcaa aaggttatga
     3661 tggacctaaa aaatatcaat caaacgatgg ataaaacagt cattgtcaat ctgcattcag
     3721 tccctctggc tcgtgagttt tctacgcgtg tgctcgcgtt aaaagctgct caggttgtct
     3781 ttgatggtcg tccagacgac ttaaccgatg aacgcttaga gcaaatttat ggcaatgcaa
     3841 tctttgaaga aaaggcaggc gaaatcgatg agcttgaaag aaaccgttca ctttaaatgg
     3901 tataaacacc tgcttattct tctgttctta attgtttgtt ttcaaggaag tgcctggatc
     3961 acgtcagctg atttttctca ggtttttcaa aactccaatc aaatgactgt ctttttatca
     4021 cgcttcattc atccagactt tagctattta cctaaattag tcgagcctat ggtgaaaaca
     4081 cttcaaatgt ctttgcttgg aacggtcatt ggcttaattt tagcgatccc tgttagtttt
     4141 ttagcgacca ctgtagtgac agaaaaccgt cttctttcta ccatctttcg ttttctttta
     4201 ggtttagtac ggaccatccc taccctgctt ttagccgcgc tttttgttgc tgtgtttgga
     4261 attggtgaag cgactggcgt gttgactatc gctgtcttta cttttggtat ggtgtcacaa
     4321 ttaatgtttc aagcaattga aaccattgac tttggcccga ttgaagccgc tgcggctgtt
     4381 ggagcaaata aaatgcaaat cgctatttgg tcgatcgctc cacaagtttt gagtcagttt
     4441 gcgagctatg ctttttacgc gtttgaggtg aatgttcgtg cttctactgt ccttggatat
     4501 gtcggagctg gtggtattgg cgttattcta aattcctcac ttgcgctttt gaattatgaa
     4561 cgagtttcaa tcattattct aacgatccta gtaactgtcg cgatcgttga taaattaagt
     4621 gaacgtgtca ggaggtccct gttatgatgc ttcgtgaaat gaacagaaga acccttttat
     4681 cattagttgc tttagtgatt ctcgttattt tgtcggccgc tactctggat tactctggat
     4741 taagcacctt ctctccttcc atgggaatgg acgttttgag agggttaggt cagcctgatt
     4801 ggcagtttct atatgatggc agcggcgagg atttgattag tttgctatta ttaaccattg
     4861 gaatcgcctg tttagggaca atgatcgcta cggtattagc gattcccatt accttgatca
     4921 gtgcggttaa cctctggcaa gcacatccat gggtaacaaa aattggcaag cttatctgta
     4981 atgttttacg agcttttcct gaactagttt ttgcaattat ttttgtgaaa gtcgtcggac
     5041 ctggcccctt tgctggtgtt atggcgattg gcgtccatca gatcggaatg cttggcaaac
     5101 tttttacaga agaaatggaa gcgatggatg agcgacttgt tgaagaaatg catgcggtag
     5161 gagcaaattt ttggcaaacg attttctttg ttcgcatccc ctatttgatg ccgatttatt
     5221 gttctttagc attaaatcat tttgaaatag cggttcgtag tgcggctacc ttaggcttag
     5281 ttggcgctgg cggaatcggt gctccattga tattcgcgat tcaaactcgg tcttggagca
     5341 aagtgagtat tattttgatt ggcgtagtcg taaccgtgtt tattttagat caaataaccg
     5401 gaattataag aaagagattg agataagaat gaatatattg catatatcag atatacactt
     5461 tcgcagagag tatgaggctt gtgaagaagg ctataaggga atgctggcta cgatgcagaa
     5521 tccccttatc cctctggagc aatgcattca tcatctcctg cagcaaacac ccttggacct
     5581 tgtgattatc agcggagatt taaccgaaga tggcgaaata gacgattatc gatacttgaa
     5641 gacttggctg gaaaatgcgc taggagaaac gacgattctt gttactctag gcaatcacga
     5701 tatcaaagaa catttttggg taggctggtg cgatgaagcc gcctcttctg ccccgtacaa
     5761 ccagatagtc aaatatcctg agtttacagt gatttccttt gataattcaa gctatggata
     5821 cgcagatggt atagtggacg atcagcaatt tcaatggctg aaaaaagcct tagagcaaga
     5881 aaaagaccaa ccgattttct tggtcaccca tcatcatcta ctgtctcacc aaagcagtat
     5941 accaaaatgg cctggtaccg aacgtttctt gaagctaatc gcaccttacg atattcgctg
     6001 tatcctaaac ggtcataccc atcacacatt tactgatgaa attaatggga tcccctattt
     6061 tactgtatcg agtatgtcct ttgttggtga agatgaaggc gatggcttcg tacgctttga
     6121 agaacgtcat gggtataacc tttatcatct cgatcaagga aggattgttc gccagacaac
     6181 agaaaacttt attccaggca acattttaaa aacacttcaa atgaaggatt aaggcattat
     6241 aaatcaaaaa aagagaccga acagctgaat acgcttcggt ttttctattt tgagtcagct
     6301 aaaggagcac gcagaatgaa cattacgttt ttagagacaa gtgatatgca tggctatgtt
     6361 tcaccaacag actattccgg cagaaccgat ctggccttag gaacggctaa agtatcgtcg
     6421 aaactgaagg aattacgggc aaaagcagat ggaccggtaa ttacgatcga aaatggtgat
     6481 ttcatccaag ggtctccttt gagttattat cttgctaaag aatatggttc agccaaagag
     6541 cttacagact tgattaacca aatgagctat gatgttcaag tgttgggaaa tcatgagttt
     6601 aactatggtg tggattatct cgaggaagcg attaagaatt atcaagcgcc tatattagga
     6661 gccaatatgg tgaacaaaaa tgaccaacca tactttggaa acgcctataa gattatcgaa
     6721 aaggtgggtg taaaaattgc tatcttggga ttaacgacac aatacattcc tcactgggaa
     6781 aagccagaaa ccttagcagg aattacgttt aagagtatcg tcgaaacagc aaaagaatat
     6841 gttcctctat taaggaaaca agcagacttg gtaatcgtta gttaccacgg cggatttgaa
     6901 aaagacttgt taaccggtga ggacacagaa gcgctaactg gagagaatga aggctacgag
     6961 ctattgcagc aggttgaagg cattgacgcc cttttcaccg gtcatcagca ccggaaaatt
     7021 gctgaaacgg ttcatggagt tcccgttgtt caaccaggct atcgtggcga gttcatcggt
     7081 gaaattcgtc ttaccgtcga gaaaaaagag gggcaagtgg ttgttacaga tcaccaggtt
     7141 gctttacact cagttgaaaa atcagagcct gatccagaaa ttcttgcagc gatcgtaccg
     7201 gtagaagaaa aactagagaa atggttggat caacccttag gtaaagtgaa cggaaatatg
     7261 cgtattaatg atccgatgca ggctcgtctt gaggaacatc cctatgtaga gtttattaat
     7321 cgtgtacaat tatttgccag cggctcagag atttctggaa ctgcgttatt caataatgaa
     7381 ggaaaaggct ttggtgagac gatcacgatg cgggacgtca tcaccaacta tatttatccg
     7441 aatactctgg cagtgattca aataaatggt gcagatttga gagcggcgtt ggagcagacc
     7501 gcaaattatt tagctgtaga aaataaccaa atcgtattca atccagcctt tattcagcct
     7561 aagccccagt actacaatta tgacatgtat gaagggattc agtacactat tgatatgaaa
     7621 cagcctgttg gacaacggat taccgaactt cgttttaaag gtcaccccgt tcttccgcaa
     7681 caaatgctgg aagtggtgac aaatcaatat cgggcaatcg gcggaggaaa ttatgcgatg
     7741 tttggtgcgg agaaaattgt ccgagaaatc caaatcgaca tgaccgaatt aattgccgac
     7801 tatttgaata ttcacccacg catcgaagca aaagtgaatc ataattttca agtgattttg
     7861 tagtatataa ataaaaaatt caaaaaggtg tgagcagttt tttgcccaca cctttgttat
     7921 gccaaattgt taggctgtct gatttccatc cagccattct ttagccagcg atctacctca
     7981 tcaaaacaaa aaattttcct ctgatggttc cttaaataag actattttga tcctttttcc
     8041 atgaataaga ttttgcatca gacaatactt catttctgaa aaagttgcgg caccaatata
     8101 gcctaatacc cctttccgat cttgattaaa tacaaaaaat aaatccgctg ctgcgatatt
     8161 taaaaaaaag tcgtcaagat ttctggatac tctttgtcta ggatcggaca tgagcgagga
     8221 taatcaatta attcaatgcc ttttttactg aaatcttttt ccatatctcg atattcttct
     8281 tggaaaacaa tacttccaga aataacagct ttcacaaaat tggcctccat ttttttattt
     8341 ttcagacact ccaccatacc ggatacctct caaagaaaag acatagcaaa aatcaatagc
     8401 agctatctct ccacggtttt ttactggtaa ttttattttt cttttggaaa ttgtatcagg
     8461 aaggtcgttc cttcattttt tcggctggtc acttcaattg aaccgtggtg caggcgcact
     8521 agttccttca cgattgataa tccaagacct gactcgccta tctttgtatt tttacttgac
     8581 ggatcggctt tataatagcg atcccaaatg tttttttgtt cctcttcaat catgccgatg
     8641 ccattgtcct cgacagtaat aaatacaggc tctttgtcaa atgatgttgg taaagagaaa
     8701 tcttagaata atttggacag aacagaaaga agaaactctc tttctgttct gtttatttgg
     8761 ttaaaaatgt tttgccatga cgaatcatga tccgtagttt gaaattgtaa aagctgcgaa
     8821 agccgtacgc attgcgtttt aatactttga tgtggttgtt taaacattcc aatggtccat
     8881 ttgaatagct gtagtgaagc gcattttgga tctgtggcag aaacttttta aacgttcgta
     8941 aagtggttgt ataggtttca ggaagaccgc tgacttctct gtttaaacag tcctcaaata
     9001 atgactgatc tcttttcttt accgcataaa gaatgtcttg gtataactga tagccttggc
     9061 gcaggttggg acaagcagat aacagtcgat cgacaatctc actttcagtc aaataatctt
     9121 taaaactggc acgccaaacc cttttttcgt agtttaactt tgcttcttct ttttgtagga
     9181 gtttccaata gcgtttcaat tttttcccta accctcgttg agagtgggaa gttcctttaa
     9241 gccgtgccgt ggtttctttc actcgatgat tcaagaaggt tctgccaata tgttggacga
     9301 tgtggaaacg gtcgatgatc aactgagcat tcgggaaaag ctttttcacc aatgaaacat
     9361 aaggcgcata catatcaata acaatccatt gaacggcttc acgagtcgct aatgaaaacc
     9421 gagaaaaata gcattctaaa taaggcaagc gtcgattttc gacaatatcc aataatgcat
     9481 ggctttgtcc gtccatcatg ataaaactca ttgcactggc aacacttcga accgatttga
     9541 attcatcaaa gcataagacc tttggcaaag cctgtttgaa aggattcaat gggcggtaga
     9601 atcgcttcat gacacgatag accgaagaag tggaaatatt tttctgacga gcgatttccg
     9661 tcatggaagt attctctttt aagcgagcaa tgacagacca acgaactttt tgactaatga
     9721 aacagtgttt ttcagcaaca gaggtatccg ctacgaatgt tctttggcaa gacttacatt
     9781 taaatcgttg tttcttcaac tccagataag tgcgatactc agacgcatca ttcagtaaca
     9841 accgaacggt tgtcgtcccc caacgaatga tcctagaggg gacgacacaa agacaatggg
     9901 aacactcttc tggcttgtac agaagagttc ctttgtaaat catggatttg agtcaatatc
     9961 ttggacacat tttagtagag acggttaagc cattttttct tttgctaatt cttcaaattc
    10021 ctgtggggtt agatagtgaa tcgagctatg gattcgattt cggttataaa atccttcaat
    10081 gtagctaaat agcgctcgat ttgcttcttc aaaatctgag tagctagtcg tgtagacttc
    10141 ttcttttttc aatgaggcat ggaaagattc gattccagca ttatcataag gtgttccttt
    10201 tctactataa gaatgcctta ttttgttggt tttaagccat tgttccactt ctcttgctgt
    10261 gtattggctg cccaagtcag tgtgtagaat cattccttct ggaatgtgat aatgtatttt
    10321 tgctttattc aatgtttgaa tgacacaatc cacagtcatt cgttttgaaa atgtataact
    10381 aataattttt ttcgtgtgta aatccatgat tgaagataag taacaccaac catttttctt
    10441 agtaggaatg tacgtaatgt cagctgccca tttctcacag atcgtttcag tagaaaagtc
    10501 ctgatttaag agattctctt ttgaaatgat cggtttatta gacctttgag gtctatattt
    10561 tttaactaca atcgacctta aatttaattg tttcattagc ttttggacat gtttaagaga
    10621 tactgaaatc ccttctttta ataaaacttg atggatcttt gtggcaccat agcgttgttt
    10681 attcgtaaaa aaaattgttg aaatcttctt tttcaactta ttatttctga tttctgtagc
    10741 tgtcaacggt ttattcttat aaaaataata gacacttcta gggatttcta ataaccgaca
    10801 taacaaagaa acagtgtaat ccttacacca tttttcaata aattgaacaa gcgaatttag
    10861 gttttccgag agaatatggc tgcggctttt tttaagattt caagttcctc atttaaacga
    10921 gcattttctt ttctcagttc agctacttct tttccagtca gtcctgtgga ctgatcaggt
    10981 aaatataaat tcttccattt gtaaatcgtt gcttcagata agccatattc tttcgctaac
    11041 cctcgaacag aacgtccagt ttgattcagt tcaacaatca tttgtttaaa attttcttca
    11101 tatcgggtca taaaaattca tcctctcgta gataagttta atttattctt gtctctacga
    11161 aaagctgtct aagatttgat actaacacca agttatcttt agaaccattt cagatacata
    11221 tgaaacaatt acatatgatt ttttcataaa aaaacagtac tgtctagtag tataaaatat
    11281 acaaatttct taaaaatttt ttcactaaaa tcactacctg aaacagtcta aaacacttat
    11341 atatcaacgt ttaatgaaac tatctccgtt tcatttcaga tacaaataaa tatagtcggg
    11401 ctccaaatcc gaaaaaaaat acccccagta gcttatccta agctactgga gatgtataag
    11461 tacggtcata taacaacggg gtagggtaaa taaatgaaaa agatggaaga atcattattc
    11521 aataactttt ttaaatactt cgttgtaatc agttacctgt ccgttcttaa ataccacaga
    11581 ataatctttt ttcccatttt caagtaaccg aagtggaatg tctttaccaa cttgctctgt
    11641 cactgcatta ctgatacctg ttagattagc taataaatct gataaagatt gagcatctgt
    11701 agaaatctct gtatcagtat ttatcgtgat tcctttatct tcatttacaa gcttccaagt
    11761 aggtggtata gctgtgtatg tttcgatgaa tgaatcaatt ctttcatcta tcgtcttccc
    11821 agtatctact tctgtctcat tactcttaga tgaatcgatt ctttcatcca tcgtctgctc
    11881 cgtaactgct tctgtctcat tattctcacc ggaaactctc ttcacaccca aacttatata
    11941 ttgtccatct ttagtgtgca tagttaaaat tcccacgctt ttactaataa attcactata
    12001 accagttctt tcaatagaga cttcaatgta tttcacacta tcatactcaa aagaaaaata
    12061 gacatgtaaa agcattttgt tgtttacatc tacataataa tcctttgact ctacttgaga
    12121 ccttcctata cggaatacag ctttactgtc tgatatctct ataccagcat ccttattatt
    12181 aatctgccaa tctccaagta gctcttctgg caagctagta gtttcttgtg aacactttac
    12241 cacttcactg gtagaggtcg aaacattcac ctccgcactg ttagaagaat tttccaagga
    12301 atcaggagcc ttagcacaac caacaagtct ttatatattg tgcagccgat attttcttca
    12361 ttcagtacac ccttgaaata tgcagtgtta gataaagcag ttcgtcctga tttgctgagg
    12421 cacccatctc ttcttgaacg tactccttga ttttcaaggc cgcccgatac tctttcggaa
    12481 aacgctgctt cactgaagcc agcaaaaaat catccttctc cggcaactct tccttcttaa
    12541 tcattcgggc aataaaaaac tgtaaatgcg tcacaaatct taagtaaagc atcgaatctt
    12601 tatcaacctt tttttcggga aacagatatc ctagcatagc caagatatcc tttagtgctc
    12661 ttaccgagag catggtttct tccatatttg cttgttcact ttgggcattt acaatgtgaa
    12721 acgcaatgtt tccagcctcc tcttctggca actgaacatt catttttttg ttgatcaatt
    12781 ggatagcata gcagccgatc tcaaattctt ttgggtaata cttttgaatt tcaatcagca
    12841 ggcgattttg aaaaacaatg cctttttgac tgcgttcaat ggcatgcttc aagtgatcaa
    12901 ccaaggtaaa aaatagactt ttattcagct taaagtcaaa cttggcgttg gcataatcga
    12961 taattcgctt gacgcaaata attagatcat ccggagcagc ctcaaacagt ttaatgtaat
    13021 ccttttttag agcatcagaa agtgaatcta atttaaatac tttttggatt ttgtcagccg
    13081 gaaccaaatc gcctttcttt agttgaaatc caatcccttt ccccatcaaa attacttctt
    13141 tgccttgctt atctaagcaa agaattaaac tgttgtttaa cgttttaatt actctcatta
    13201 gattcaccgt tctctctaag ctaagccatt tcttgcgatt actttttgat accaaaagaa
    13261 gctttctttt tttattcgtt ttaattcttt aagattctca tcggttcggt caacatatat
    13321 aaaaccataa cgcttattga agccttgatg ggtactaaca acatcaatcg ctgaccaagg
    13381 taaataacca aaaacatcta caccatctgt taaagctgct tgaatagcca gaatatgttt
    13441 ggctagataa tcaattcgat cctggtcatt aattcgtcta tcttcctcaa ctatgtcggg
    13501 tgccccatag ccattttcag taattaaaat aggtaaatca tagcgatcgt acaatttcct
    13561 caatgttaat cgtagtccag tagggtcaac tacccagcca tatggcgttt tatctacata
    13621 aggattttca gctgcccggt agacaccttc ttctcccaac atgatctgtt gatcccccgc
    13681 tctagcggaa acatctgatc cgtcattttt gctggcagcg atggtggcag ttgaataata
    13741 attaatcgca ataaaatcgg gtttaccgga ggataaaatt gcctgatcct ctgcctcaat
    13801 tttaggatat aatccacgat cattcaaata gttttcaaac aaataattgt attttccccg
    13861 aactgctaca tctaagaaag accagcctct caatgtttcc caattatggg ctgcaattgc
    13921 atcttctgga ctggaggtag cttgatacat agccgttaaa ttgattgctg gaccgatttt
    13981 tcctttaaga ttcaactgat gatacaagtg aattactcta gcttgagcta ataaaacatg
    14041 gtgattaatt tgaaagagtt ctttttttga aggcagctct ccacttggtg gcaaaccaat
    14101 cgctccagga tgaaggatca tcgtgttttg ctcattaatt gtcagccaat agttcacctt
    14161 gtcaccatac tcagtaagca atacctgtac atagtccaca aaataatcga tagttgctcg
    14221 atttaaccaa ccgccctgct cctctagaaa ataaggtaaa tcgaaatggt acatggtgac
    14281 aatcggttcg attccctgat tcaggcattc atcaattact tgatgataaa aagaaattcc
    14341 cttttgattg gttttattat tttcaatatc cataattcgc gtccaagcga tggaaaagcg
    14401 aaaagctttt aagcctaatt ctttaaacag ctgtatatct tctttatagt gatggtaaaa
    14461 atccgaggca acttcaaaat tagctacccc ttctgtatgc tgatacttgt caataataga
    14521 cggttgtttc ccatcctcct gataggcacc ctctgcctgg taggcactaa tggaggcacc
    14581 ccataaaaac ttctctggaa atgctgaaag ctgtttgtat tgcacaaaaa tcctctcctt
    14641 aactaatttg catcaatggt tcgtgttcct ttaagcttcc gcttgcttca ctaattcctg
    14701 cgtaattttc actgttggtc actaccacaa tcactgtatc atcgtagcca gcgtttctaa
    14761 tggcagcgaa atcggcgttg attaataatt gtcctgctga cacctgatct cctgctttta
    14821 caaatacttc aaagggttcc ccttttaaat tcacggtgtc gatccccaca tggatcaata
    14881 attcaatacc ttctttagaa cgtagaccaa tcgcatgttt agattctaaa atagtaatga
    14941 cttctccctc aacaggtgaa taaatgctgt tttcttctgg atgaatggct acgccctttc
    15001 ccaatagtcc cttagaaaag acagcatcgt tcacttcaga aataggacac acggttcctt
    15061 ttaccggatt ttcaacaatg actgcttcgg ctattgccgt ttgctctgat tcatcagaag
    15121 tatcgtcaaa tccaattaga taagcaatga taaaggttgc aacaaaggcg attacacacg
    15181 taataattgc gtgaacaata ttcattggat tttctccaat aaaggctggt aaggctgcta
    15241 agccagggga aacaaaggca tatctgacta aaccgctcaa gccagcatac aaaccagcaa
    15301 ttgcaccacc aatcatggaa gcaactaatg gttttttcag cttcaaggtt actccataga
    15361 gtgaaggctc agtaattccc attaaagcag tgatcccagt ggacacagct agctgcttca
    15421 actctttgtt tttagttttc gcggctacag caaaggtagc acctgattga gcaatattag
    15481 aagccagcat tcctggccca ttgatcattt cagaacccgt actgctcaat tgcatagtag
    15541 cgattggcgt cattgcccaa gctgtacccg taaccaccaa aaatggctgc aaaccaccca
    15601 tcaaaaatgg aattaaccaa gctgctttgc cgttaatcca ttcagccccc attgctataa
    15661 gatcgttcag caacgttcca aacggtccaa tgacaaccaa cgctaaaggc cccataatta
    15721 aaaataccag catcggctta gtaaagaatt taataaacga aggcgaaatt cgatccgcaa
    15781 agggctctac ataggacatg atccaaacag taaagataat cggtaaaact gatcccgcat
    15841 aatctgcagc taataccgga attcctagaa aagaaacggc atcgccagta gaaaaaagct
    15901 gtgaaatatt tggatgaagc aaaatgccag caacagtaat cgccaaaatt gggttgacat
    15961 caaactttat ggctgcccca taggctaata gtactggcat aaaataaaag gctgcatcag
    16021 caatagtatt caaaatgatg taagtttgac tactgtctga tagtacacca gtcaaagtca
    16081 agacggccaa aatggctttt accatcccgg cacctgttat agctggaatc atcggtgtaa
    16141 aggtggtaga aatgacacta atcaatcttg aaataatact ttcttgattg tctgaagagg
    16201 ggcccttttt aattgaagtt cccacttcct tttgaatttc cttgaaggct gtttggactt
    16261 cattgccaat caccacttgg tattgtccac cgctatccac cacactaatt acaccaagtg
    16321 ttttttctaa ggctttcgta tcggctttcc ttttatcttt gagttcaaaa cgcagtctgg
    16381 tggcacaatg ggttaagctg accacatttt cttttccccc aacctgttgc aatacatttc
    16441 ttcctacttc tctgtaatcc attattctct ctccttaaag cagtaaaaaa gaccaagtca
    16501 aaccacgccc caatcaacat tgaagtgtta gtttgtcttg gtcttgcctg cataatcagt
    16561 aacatgccaa taacgttatt ttgctgtaat ccaataatag cacattatga tagcgcaatc
    16621 aacagggaat ttaatttttt atcttttcgt ttgaccgtat agggtaatat aacagttaga
    16681 tcacatcaac tagggtatat ctgcgtatac ttactgctaa aataagtata tctaatatta
    16741 actataccag taaaaccatt cctacataac cagcgggaaa ttcccaaaat cgtgaaagca
    16801 tcaaaaatgc atataacgga tcacacaact tcaacaattc tgctcttggg aaaaattgat
    16861 gaatttggtg agtaaaggat ggaataaaca gcattccaac aatataggca acaatagtga
    16921 tacttgtttt tttggtaaaa atcagtaagc aatagccaat ttcaatcatt ccgagatata
    16981 aaggtatcga tagaatgatt tgggctagta ttcttaaaaa ttaactagca aatgtttaaa
    17041 ctgatttatt tctaatctac atgtagtaag tatttcaatt ccaccaatta tcaataaaaa
    17101 taccaaacat atccataata attttttctt tttcatttct tttatattgt tataacagtg
    17161 aataacataa aaattcccga caatcattgt aatatttttt tgtcacctgt attagtattt
    17221 aatttatagg aaactataaa aactccctag tgaatttaca cctttgggag ttcctgtttg
    17281 gacggtatgc ataatacatt taaatcaatt taacattaac acctcagcat atggtatctc
    17341 cacatatata cggtctttct ttggatagta ctcaatattt atgttgatag cacttccatt
    17401 gtctaatata gctttagccc ggtatgtgtt atctccattt tcatgagtaa tcgtcacatc
    17461 atcacatgat cgatttaagt tgtactgttc ttgtaaaatc tgtgttacca atggtttcga
    17521 tgacttctct aatccagatg tacctgtcat ttttgaaaaa atgataccta taatagccaa
    17581 gacaacgata actataatga taaacttctt gttcatattt actttattca actttttatc
    17641 tcctatctcc aaaataattt gctcttatcc ctcttatcag tacattgaca tccctaaaag
    17701 tacaccaaag attgctccag ctacccctgc tatcatcaaa atcgtaccca tttgttcatc
    17761 tttatctcga tataagtagc ccataataac agcaacagca ccaaatacaa caggaataaa
    17821 tgctaacgct actaccatag aaatccaacc aataatcaaa tacagcttcc ctgtctcttg
    17881 tccatgtacg atttgttcct tcatttcatt aattgtctgc tcagtacttt tctttactgc
    17941 gtctgctcca gttgtctcat ctgtttcttg tagtgctccg caaaactggc aatacttact
    18001 ttcatctgtt atttctttgc cacattttct acaatacatg tcttctcctc ctaaaaacat
    18061 tcaattgttt attagttaac tgtttacttt attaaataca tcagaaaaca gctcattcat
    18121 tggtacactt aatatctcag aaagcatctt catttgatag ggtttaggaa tcgttctccc
    18181 tgtttgccac gaacttacac attgctgtgt aacattcatt tttttgctaa ctccgtttga
    18241 gaaagtcctt tttcttttct gtatcggctg agattactta cttttttcat gattctcccc
    18301 tcctgtttta ttatatacaa caatatgatg tatttcaact cataaaatat aaaaaaactt
    18361 caaataccat tacaaataca acaacttgtt gtactatact gagatggggg tgtattaatg
    18421 aaacagaaac aatatgcaaa ggtcattaga gaaaagcgaa aagctctcgg gtggacacaa
    18481 aaagaattag ctgaaaaaat cttctctaca caacaggcag tagcaagatg ggaaaattct
    18541 gtaacagagc ctaacctcga tagcttaacc gctctttcta gagccctagg aacccctgta
    18601 agccattttc tagacaatgt tgtcgtagat tatgaggaag agtttttggc tctctatcgt
    18661 tctcttagca ctgaagatgc agttcgaaca attgactata tgaagctatt aaaaaggcaa
    18721 gaaaatgaac gcaatcagct attgaaagat tgaaaaataa ataacccacc gaactttaac
    18781 ggtgggtgta ttgagatgaa ataagattaa gagctatgga taacctgtct agtttaatac
    18841 aattgggtct tttctcttcc ttactctccg tccatcatct cttgttacac ttgtaaattg
    18901 ataaagagga actaattcaa ctcctgataa tatcaattct tttattactt catctatccc
    18961 tgctcctttt gctaggtaga ctaaaaaact actacttgct ttcacattgt atagtctctt
    19021 aatatcctta gaagctcgtt caagagtgaa tccttgttta acaaagtagc ctctgttttc
    19081 ttttaaagca ttttccacgc tgttattccc aacattacgt agacgttcac aaacagtgtt
    19141 agtaagttct ttctctgtca ttagatatgt tccttgccac gataagccct gtaaaacttc
    19201 atgtgcttca tctaaaatca attgtttttc cttgctaagt tctgatcggg aattttgagg
    19261 aaatactctt ttagcctctt tttcgttaaa acatatctta acccattcat aagaaaaata
    19321 ttgatatgta aaatgaaatt tttccagaag tggaaggata tcttcattca atttttgaat
    19381 cacagaagtt gcattaaaaa cgtctaatcg atagacattg cttctcttat gattaaagtt
    19441 tcctaacgct ttctcttcct ttaacctatt taggtattcg agcatcttca aaggaacatc
    19501 ttcatcatct aattttttta tcaatcctat aaaagtcata agtgatagta acttattaca
    19561 tttatctatg tcataagttt taccatagta aaaactcatt tttttagcta attgttcccc
    19621 cgacaaaata caagtcacac tttccttact atcatcaaaa aaattaacat cagaaagcaa
    19681 gacatcatag acacgtcgca tttcctctag ataattcctt attgtcctga aaagtttgtc
    19741 tttcattgat tcaagagtgt caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg
    19801 tgtaggatac aagtctaggt tctctaatag ccaattaaat gtttctaccc gactgtcttt
    19861 ctttaaaatt agcatcacaa ctccaataaa attttcactg atatcacaat tactggaatg
    19921 acaataaaaa atggaatgcc cagttttact ggtaaaaata ctagcagagg gattatgatc
    19981 gttgtgaaac agacatctta agtttttact tgacttaagt aatttattca tatcaatggt
    20041 taacaatctt tcataaatct cattaaaaga catgtcggag gaatcaaaca ggcagtcttt
    20101 aaaccactgt ttcatttctt ctttgtcgtc attttttatc aacttaacaa aatcggtttc
    20161 attgactagt tcatactctc tccctgaatc actttgacaa tttttagaac atgtcatggt
    20221 aaaatcaatc ggaagctcag taatatctaa catgttgtct tcattaatta ttatcactgc
    20281 atctgactta tatcctccaa aaaacattct attcgaagca tttacattgt catcacaccc
    20341 ggggatgttc tttttcaagt attcgtaaac agcaaccatt ttaccatagt cagtaattgc
    20401 ttcttttaat agaaagacaa tcttgtattt ttctagattt tcagagtacc gaatactttt
    20461 ttgtatcgca aacgcagaat tatgaactaa attgatagat aaaacctttt ctatgcttaa
    20521 gtatctacta tcatctttac tcaaatctac taccttcccc ttctcatctt taacagtgtt
    20581 atcgacatcc agaataatta ctctggtttc cacaaaactc tccttgtcat tgcctttatt
    20641 ctttgtcttg cttggaataa atgattgtga tgaatttagt atctctacaa actcatctct
    20701 tgtaacttct ctatagttat ctaaacacct atctcttaca tcagtttttt ctttttttgt
    20761 aactggcttc tctaataatt tttctttatc tacataaatt ggaatattaa tcattgatgt
    20821 ttccatttgt gtttcctcct tataaaattc tgttaaagac taaaacatac agataataaa
    20881 aacaaactct ttattactat atgttttagt cttatttgtt tactcaacct ttataccgtt
    20941 ccatgaaact atcaatatca gattttttaa atctaatgac cgtatcaatt tttataacag
    21001 gtaacccgta ttgagaaaca tattttctaa tcgttcctac tgatacacct agatattcac
    21061 ttgcctgctg atagtccata tactctagag tgactccaga aataatgtct tctagcatag
    21121 gctttagcac tgtaattatc tctttcactt gttgttcaac ttgtatagaa acaatgctat
    21181 caatgatttg tagagacata tttccccctc ctttcgtgat tgcttgaaca aattttctaa
    21241 gaattatctt cgtatttttt gctcaaaata aaagtatttt gttattaacc gattaatcaa
    21301 acaaaaaatg attaccagtt catcgacata cacataatac ctcgataaaa aagaggtgtc
    21361 aatatctttg taaaatttat ttacaacacc cctttttcga ggtatactaa ttttaggagg
    21421 tgtggtcaat atgataaaac gtccaccaat aaattattta gaacgaaaaa agatactcgg
    21481 aacaaaaata aaagctataa gaaagagtaa aaaattaaca caaccagcat ttggtcttat
    21541 gattaacaac ggtcaattaa ttgacaaaaa aactatctac gaatgggaga agggaaccta
    21601 tttaccaata ccagagcgat tatcccgaat tgctgatttg ggaaatatga gtatagagga
    21661 gttagtttgt ggcaatgtag aagaatatat tttgggaatt attctttata gagatagcat
    21721 tgtactagat ggtataacat ttccagataa aaacctgttc cagcatcttc gtcaacagtt
    21781 cccaccagta cactctaatt tagatacatg gctggataga tattccaaat tagaaccaga
    21841 gatgcaagaa tttattgcta acaagacttg taataaagtt aaaaatgaaa aaattagtct
    21901 tttcaatatc ttaaaaatag aagaattatt catcaatgct attgtagaag aatttgacaa
    21961 taacattctt ttcctcacta gcagtataga agaactacta gaaagaatgg tagatgaatg
    22021 gctacctatt caattgaaag acatgtctta tcccgaagaa gctgtgagag aaattactga
    22081 taatataaac aagctagaac aaacgatttc atcaattggg aaaaaataca ctaagaaaaa
    22141 aatgaaggga ggtgatacca tctagtggta agtactcctt gtaaactaag aggagatgat
    22201 ttcatggcaa aaatatcaaa gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa
    22261 ggacacattg ccaccgatcc acgaactggt gaaaaaataa atactacgag aagaggtttt
    22321 agtagcaaac aagaagctca aaaagattat gacgagtaca gacatcaaat attatacggt
    22381 gttaaaaaga aagcacctga tatgacattt gaagacctgt ataatgaatg gataactcat
    22441 cagcgtacca gtgttaaagc ttcaacaatc gcaatctcag taagatacgc aaataatcaa
    22501 atacttccag catttggtaa gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa
    22561 gtggtagatg aatggcacag taaatatgaa agttacgatt atatgagaaa acagactgca
    22621 caaattttac gctacggggt tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca
    22681 cttcttccac gaaaaaaaga gtatgagaaa aatcgtaaat tttactcaaa agaggagctt
    22741 aataatttac tggatgcttt taaagatttt ggtaacatga aacaatacgc cttcttcaga
    22801 ttattggcat acacaggtat gagaaagagt gaagtactcg ctttacagtg gaaagacata
    22861 gacacgttta ataaagaact acatgtcaat aaaactcttg ctgtagatga atttggtaaa
    22921 gttataattc aatctccgaa aacaagagct tctagacgag ttatctcttt agatactgag
    22981 actctttcta tcctcaacaa ctggaaatta cagcaaaaag aagagtattt aaaacttgga
    23041 tacaatacta gctctaaaga gcaacatgtt tttacaacag ttaaaaacac tctatacatt
    23101 ccaaacactg ttaatgattg gttaagatat attttgaaaa aatataactt gcctcgtatt
    23161 acacctcatg ggtttagaca tacacatgct agtttattat tagaagcagg agaatctgtc
    23221 aaggtagttc aacaacgatt agggcatgaa aatagtaaag tgacattaga catctatgca
    23281 catattacaa ataatgcacc taagaaaaca ggtcaagact ttgctgatat gatggctcat
    23341 cagtaaaaga gctggtcaaa atctggtcat ttctagtata caggcaaaac aaaaaagcta
    23401 gaacccttat atatcaaggg ttctagctcc tataacaggt ttacccaaca ctgccttcca
    23461 tctcataact gatcaatcga ttgagttcga ctgcatattc cattggaagt tctttggtga
    23521 atggttcaac aaagcccatg acgatcattt cagttgcttc agattcggtc aggcctcggc
    23581 tcatcagata gtagagttgt tcttctgaga tttttgagac tttggcttcg tgttctaaag
    23641 agacttggct gttgtggatc tcattgaatg ggatcgtatc ggatttcgac cattcgtcca
    23701 tgatgatcgt gtcacattcg atatgagaga tcgaacccgc actgtttttg gcaaaggtta
    23761 cttgtcctcg atagtttact tctccgccgt cttttgaaat tgatttagag acgatagagc
    23821 tagatgtatt tggtgcattg tggatcattt ttgcacccgt atcttggatt tggtttgctc
    23881 ctgcaaaggc gatggagagc atggtgcctc gtgcaccttt tccatctaag taaacacttg
    23941 ggtatttcat cgttgttttt gcacctaggt ttccgtcgat ccattcaacg gttgcgcctt
    24001 cgtatgcttt tgctcgtttg gttactaagt tgtacacatt gtctgaccag ttttggatcg
    24061 ttgtgtaacg gcaatacgca tcttttcttg taaagatttc tacgatggcg gcatgcaggc
    24121 tgttacttga ataagtaggt gccgtacaac cttcgacata gtggatgctt gctccttcgt
    24181 caacaatgat cagcgtacgt tcgaattgcc ccgtgttttc cgcattgatc cggaagtacg
    24241 tttgtaatgg aacatcgact ttgacgcctt ttggcacgta aataaaggtc ccacctgacc
    24301 atacggctga attcagcgct gctaatttgt tgtcggttgg cggtacaagt tttgaaaagt
    24361 actctttgaa taattcaggg tattctttca aagcagagtc agtgtcagta aagacgattc
    24421 ctaacttttc gaattcatct ttcatattat ggtacacgac ttctgattca tattgtgcgg
    24481 aagcaccggc tagataagct cgttcagctt ctggtatacc aatcttttca aatgtatctt
    24541 tgattttttc tggtacgtct tcccagtcac gagcgggttt gtcacttggt ttttggtaat
    24601 atttgatggc atcgaaatcg atgtctgaaa ggtcggggcc ccatgtttgc attggcattt
    24661 tgttaaatgt ttctagagat ttcagacgga attcaagcat ccattctggt tcgcctttga
    24721 ttcttgacat ctcacggatc acttcttctg tcaagccttc tcctgtactg aaaaccggtt
    24781 cgacatcatc gtgaaacccg aatttatatt cttctaattc tggtacgccc atgttctcac
    24841 tcctcttcct tgtggtaatg atggaaagct gcggtaccat cgttttccat tgcttttcct
    24901 agtgctttcc aggcaagtgt cgcacatttg atccgagcgg gaaatttagc tacaccacca
    24961 agcatagcag catcgcctaa ttggtcggga tctttgactt cttttccttg gacaagctgt
    25021 agaaagtcta cagttaaatg ttctgcttct tctattgatt ttccgatgac ggcgtctgtc
    25081 atcatcgagg cacttgccgt actgatggag cagccactgc cgtcaaaggc gatatttttg
    25141 atgattccgt cttttacatc gacttgcaat tcgatcacat ctccacatgt ggggttgttc
    25201 aattcgatct tgcttgtcga gtcagtcaag cttccacgat gatgcggatg ggaagaatga
    25261 tccaagatca cttgacggta taaattgtct aatttagata gtcccatgtt ggaaaaactc
    25321 ctttgttgcc atgattgctt caactaaacg gtcggcgtct tgcgttgtgt tgtagaaata
    25381 aaagctcgcg cgagcagtcg ctgatacttc aaggtacttc aatagcggtt gcgcacaatg
    25441 atgacctgct ctgacggcta ccccttccat gtctaaagct gtcgcgacat catggggatg
    25501 taacccatcc aaattgaatg caacgactcc tgtccgaaaa ttcgggtctt gtggaccata
    25561 aacagtcaat ccatcaattg cttgtaattt tggcaacaca taagcggcta gttcttcttc
    25621 atatcgatgg atattgtcca taccgagttt ttgcaaataa tcgattgcat ggcctaatgc
    25681 gatagcgccg gcgatatttg gtgtccctgc ttcgaatttc caaggtagtt ctttccatgt
    25741 actgtcgtat aattcgacaa aatcgatcat ttcgccacca aattcaacag gttccatttc
    25801 ttctaaccat tttcgtttac catataaaac accaatacct gttggtccgc acattttgtg
    25861 tccgctgaaa gcaaagaaat cacagtctag tgcttggaca tcaatggcca tgtgcggggc
    25921 agattgagca ccatctacta cgatgacccc gccgttttca tggacaagtt cagctaattc
    25981 ttgaacagga ttgaagacac ctaagacatt ggatacatga gcaatggaga cgattttggt
    26041 tttgtccgta atctttttcg ctgcatcctc catatccagg aagccttctt ctgttagttc
    26101 gatatatttc aagacagcac ctgttcgttt tgccaactgc tgccacggga taacattaga
    26161 atgatgttcc atgtaagaga gcactatctc gtctcctgct ttgatatagc ggtcgccgaa
    26221 ggttctggct acccaattca agcttgtcgt cgtaccacga gtaaacagca cttctgctgt
    26281 ttcttttgca tggatgaacg cccgtacttt ttctcttgct tgttcataat catgggtcgc
    26341 gcgttctgct aacgtatgga caccgcgatg aacattggcg ttatcgtgtt cgtaatagta
    26401 cgctaatgcc tggagtactt gttttggctt ttgggtcgtc gctgcattat ccagataaac
    26461 taaaggttca tcattgacgt cttgaaataa gataggaaaa tcattgcgta gctttttagc
    26521 atcgatcatc cattcaactt cccttcgatt acttcgacta attctttccg aacttgttct
    26581 acagggattg ctgttaagac agaaccgagg aatcctcgaa tcactaagcg ctctgcttct
    26641 tctttatgca atcctctact catcagatag tacatttctt ctggatcaac tcgtcctaca
    26701 ctggcagcat gtccagcagt tacttcgttt tcatcgatca aaagaatagg attcgcatca
    26761 ccacgtgctt tatcagaaag catcaagaca cgactttctt gttgggcatc tgcacctttt
    26821 gcccctttca agatgtggcc gataccatta aaggtcaatg ttcctttttc tcggatcact
    26881 ccgtgttgca aaatatgccc gatcgtatga ggggctttat tggttactcg tgtatcgatt
    26941 ccttggattt gtctgcccga gctgattgcc acgattttga cttctgcgtg tgcaccttct
    27001 cctgctaaat ctgagtcaaa gtcagcgatc acatgaccgt cattcatgac accaattgcc
    27061 cagtcgacag aagcatctcg taaaatgtgc ccacggcgat tcatataaga agtaatattt
    27121 tctcctaatt gatctacggc tgaatatttg atttttgaac cagctttagc gatgacttcc
    27181 acgatgatat tacctgatga ttttgctact tgttctttgg ttgtctggaa acgttccaga
    27241 taagaaaatt cactatgttc atctgccacg atcaacacat gcttgaagaa gtgctcatcg
    27301 gatgcgccat cttgaatgaa taaggactcg agtggttcat cgatcacgac atttttaggc
    27361 acatacagga aaataccgct gttcataaaa gctacatgga gtgcagtcaa ttggtcttcg
    27421 ttcatgttta ctgctttttt catataatat tcttggacta gttctggata ttcgatcatt
    27481 gcagtgaaca agtcggtaaa aatgactcct ttttctgcta attccacagg cagttgttca
    27541 aaaatcgtcc atgaaccttg ttggacaagc acaggattgt ctttcattgc atcaaatgcc
    27601 ggaatcgtgc ctgtttcact gatggtttgt gtttctttca catcaaataa cgaccagcga
    27661 tggaatttca cccgatcgat atgcggcaat ggcagttcat ctgctttcgc tagtgcgtct
    27721 tgacggaagg ttctcatcca atcaggttcg cctttactta aagaaaaatc atttaccgcg
    27781 tcaagataat cgagccagtt tttttctttc attcttgctc ccccttacgc ttcttcttct
    27841 ttatagtcga ttcctaattc tttactgata ccagcgtagc cttctgcttc cagacgttta
    27901 gctaggtcag cattccctgt catgactact cggccttcca tcatgatgtg aacgacatca
    27961 ggtgtgatat agttcaataa tcgttgatag tgggtgatga tcaatgcacc gaaattgtct
    28021 ccgcgcattt catttactcc tttagcaacg actttcaaag catcgatatc cagacctgaa
    28081 tcgatttcgt ctaaaattgc aaatgtaggt tctaacatca acaattgcag gatctcattc
    28141 cgtttctttt ctccgccaga aaaaccttcg ttcagataac gttcagccat ttcttctggc
    28201 atatttagta aagccatttt ttcatctaac tttttcaaaa atgccataac agaaattttg
    28261 tcgttttcat cacgtttcgc attgatcgct gcacgcatga attccgcatt cgtgatacct
    28321 ggtatctcac ttggatattg catagctaaa aataagccaa gtcgcgcacg ttcatctact
    28381 tccaagtcta aaacattttt cccgtcaaac aaaatttcgc cttctgttac ttcatagttt
    28441 ggattgccca tgatagcggc agataaggta gattttcctg tgccgttagg tcccatgatg
    28501 gcatggattt ctccggtttt cattgttagg tttacgcctt taaggatttc tttttcctcg
    28561 atcgacacat gtagattttt tatttctaag acagacatgc attatacccc caaattctct
    28621 ttcgttctca ctcattttag actaattgag aatgaagcgc aatgaccttc cttactaaaa
    28681 tcaaatatct tttatttatt attaaacaat tttgatttct aaattagaat aggtataaaa
    28741 aagatgagaa ataagccatt acagacttat ttctcatctt ttttgttcca taccttattt
    28801 tgcatcagcc tttactggtt taacagagcc gccccatttg tctgtgatcc attcttggac
    28861 ttctttgcgg tgaagcactt caatcagttt tttgattttg tcactgtctt catcaccttt
    28921 acgagtcgca ataatattca cgtaaggaga gttgtccttt tcaagcaata cggcatcttc
    28981 taatggattc aaccctgcgc cgtaagcgaa gtttgcgttg attgcaacta ggtcaccttc
    29041 atcattttgg tacgtagaag ctaaaagtga tgggtcgatc gtatggttga acttcaagtt
    29101 cttagggttt tcttcaatat catcgaatgt tgctgtttcc agatctactc catctttgac
    29161 tttgactaag ccagcatctt gtagaattgt gatgatgcgt ccccagtctg attcagaatt
    29221 tgaagtaatg attgttgcac catcttttaa ttcggaaaca tctttgactt ttttagagta
    29281 caagcccatt ggttcgatgt ggacagcacc ggcattgaca aagtcatatc ctttttcttt
    29341 gatttctttg ttcaaataag gaatatgctg gaagtaattg gcatcaatgt cgccttcttc
    29401 caaagattgg ttcggtaata catagtcatc gaatttgacg atttcaagat cgattccttc
    29461 atctttcaat aatggtttca catgttccaa aatctctgcg tgcggtgtcg gtgaagcgcc
    29521 gactttcaat gtcgtgtcgt ctgctttatt tgctgaatct ttgctgtcgc tgttgttacc
    29581 gcatgctgct aatcctacag tcagcaaaag cgctgctgca aatccaaaaa ttttcttttt
    29641 catatcctac atccccctat atcctattat cttttgtctg ttttcttagt taagaaatca
    29701 ccgattcctt gaacgataaa tacgattagt aaaataatta aagtcgcaac gaatgtcact
    29761 gttagattac cacgctggta gccttcctgc caagcaagac ctccaagtcc acctgcgccg
    29821 atcgcgccgg ccatcgcagt aaatccgatc atcgagatcg ttgtaactgt taatccagaa
    29881 atcaatgcgg gaatactttc aggtatcaag accttccaga tgatttccca gtaacttgct
    29941 cccattgcat ctgctgcttc cagtacacca gggctgactt cacgaaaagc aatctctact
    30001 agacgggcat aaaatggtgc tgcggataaa acaagagctg gaatggctgc ttgcgcacct
    30061 agcatagtgc ctacgattgc tttagtaaat ggaatgatca aaaccatcag gatcataaat
    30121 ggcgttgacc ggaaaatatt actgatgatc gatacgattc cataaatgat tcgagcatac
    30181 ggtttgtttt tgcgtccaat agagtaaagg atcaatccca aaactaatcc gatgatcgtc
    30241 actaagacca ttgagattaa tgtcatatat agtgtatcaa ggatagcctg attcatcgtt
    30301 tccgggttga tttgtttaaa atctagatat gtttctgaaa agcttttatc cacgatggat
    30361 cacctcaatt cctactcctt gttctttgat gaacacttct gcttgatcta attctttggt
    30421 ttcaccagtc atcaagacag tcaatgaacc aaaggaacct tctttcactt gtttgatctt
    30481 tccatacaca acgttgacat cgatgttata gcgtcgaatc gcttgggaaa tgactggctc
    30541 gttggcattt ctttcgctaa aggtcaaagt tgccaaacgg ccgcttggat tttctttgat
    30601 gagttcagct aatagttctg tcgaatcagc ttctggttcg atgtcttgtt gtacaaagcg
    30661 tttggttact tcttttttcg gttgtctgaa gacagtcaat acgtctcctt cttctacgac
    30721 tttccccaac tccatcacag cgactttgtt gcagattttg cggatcacat tcatttcatg
    30781 tgtgatcaag acgatggtca aattcaattt cttattgatc gctaacaata agtctaatac
    30841 ttcttctgtt gtttgcgggt ccaatgcgct agtagcctca tcacaaagca ggatctcagg
    30901 atcatttgcc aatgctcgtg cgataccgac gcgttgtttc tgtccgccgg aaagttgtga
    30961 aggatatgct tgtccgcgtc cttctaaccc gactaaacgc aacagttctt ctgcccgttc
    31021 tttacgtttg ctctttggta cgccagctaa ttccagcggc agctggatat tttcaagtac
    31081 agttcttgac cataacaggt tgaaatgctg gaagatcata ccgattttct ttcggaatgt
    31141 acgtaattct ttgtttttta attttgtaat atcttgatcg tttacgatca cttcgccgct
    31201 cgtgggaagc tcaagtccat tcaggagacg gactaatgta ctttttcctg cgccagaata
    31261 gccgacgatt ccataaatat cccctttttc aacgtttagt gaaacgtcat tgacggcttg
    31321 gatgtttccg tttttcccat tgaatgtctt tttgacattc gttagttgga ttaatgacat
    31381 gccattcaca tctttctctt ataatttttc aaacaaaaaa gccttcgccc tcttgcctta
    31441 agcaaaagga cgaaagcttg aacttccgtg ttaccacctt gatttaccgt tacttcgcaa
    31501 taacagcctc ttccagtact tggacttagc ttctttccgt atactgtcgc gctgtaacgg
    31561 gcactcccgt agtaagtttg cttacgctcg cttactctgc tctaagacca tcttccatct
    31621 cattttcgtt acccattttc agcaaacagg gctctcttca aacgtccgtg acatgtactc
    31681 ttcttttcaa agctttctcg tttcatatag gattgcttat gattatagca actggaagaa
    31741 tcagtgtcaa cttttttcaa gtgattttct gattttataa ttcgtcaaat tcttttggat
    31801 caacatcttt gaaacttaag atccacgcat tcatttcatc tgaatcattc aagatattga
    31861 tatcttcacc gattttatca ttaacagaag aaactgtacc cgttagcggg ctggcaaatt
    31921 cattgaccgc tttttccgct tcaacttcga tcagaggttc atcttttttt agcgattgtc
    31981 ctgcttttgg cagattggca aacgtgatgt ctccaagttc ttcttgcgct tcatttgtca
    32041 aaccaacaca gtattctttt ccattaaata agatccaaag gttgtccttt ttcttcaaat
    32101 gcttgcctgc cattttatat cagttctcct tcataaattt tttcattgaa tccaattgca
    32161 acaagctggt cctctcgtaa gatcagtggt cgcttgatca gcataccatc tgtcgataag
    32221 acttggctcg cttttgaagc cgtaaactcg cctacttgat ctttcagtcc aagttcccga
    32281 tatttcatcc cgcttgtgtt gaacaggcga cggattggta cttgactcgt ttctagccaa
    32341 gtctcaatcg ttgaggcctt cggtacttct ttgatcatat caacggtttg ataactaacg
    32401 ccatgctggt ctaaccacgc tttggctttt ttgcatgttg aacatttcgg gtaccagtaa
    32461 aaggtgtaca attttcttac ctccttgaag atcttgcagg tgcttcattt tggtatctca
    32521 tcgataatat caacccgata ccgatcatgt tccctaaaat cgaggatcct ccctgactaa
    32581 tgaaaggcaa tgggatccct gttaaaggaa gtaatccgat atttgctcca atattctcaa
    32641 agacatggaa cagcagcatc atgatcaaac cgcttgcgat ataggcgtaa aattcattat
    32701 tcgtatcgaa acacacccga atcatacgat agattaaaat aaaatacaag aaaatgacga
    32761 atgcaccacc gataaagccg aagttttcac cgataacggt aaaaatcata tcggactcac
    32821 gaacaggcac atagatattg cttacgttga atcctttacc aaacaagcca ccggtaccaa
    32881 ttgccaaaag tccttgggcc ggctgataac tcattcctga cgtatcatgg aaagggtcca
    32941 gccatgaatc aatacgtgca aactgataag atttgaatcc aactttataa agcaagtctc
    33001 ttccgccttc agtcgtaacc aagaagatcg ttcctgctcc aacgactact gccaagatta
    33061 ctacaggtgc gatgatgcgc caagagattc cagacatcag gaaaatcccg ccaaagatcg
    33121 caagaaagac aagcatcgtt ccaaagtcat cttgggccat gatcaatgct aaaaccggta
    33181 ttgtcacgat caagagcttc ccaatcagcc aaaagtccga tttcatcgtc cgttctttta
    33241 cttgcgtatt atgtttagtt acgatcagtg ccatcatcaa gatgtacgca atcttcatca
    33301 actctgctgg ctggaaagta aacgcaccga atcgaaacca gtttttagac cctgttgaag
    33361 cagctaaatt ctgatcatag aatttgagca agagtcccat taccactaac cccaaaccat
    33421 aaaggtaagg agtcagtttc cagatccatt tggaattcaa atgcatgatg acaacgattg
    33481 ctgccgctcc aactaaatac cagacaactt gcatccctac gcctttcaag actgctggat
    33541 tgttcggatc atggctaagt gctacatata atgagagcag accaatcaaa cataacagaa
    33601 agactggtaa aatcacgcca taatcaatac gattatcgtt cgaagctttt aatttttttt
    33661 ccatgtttca tcccttttct taaaaaccat actgctgatt attatagcgg tccagttaga
    33721 taatggaaag tctttccata gacatttggg aaaaattaac tttccgtttg tgcagttgct
    33781 tgagcaaatg cagtacaaaa gcctactgct tatctttagt gtatcataga actttttttg
    33841 atacatgcaa ttatctacca gctgagattc tcctcgctgt gagaagtttc tgtgctttca
    33901 ttgtatcgaa ggatctcttc ggcaatctct agcagctgat cagaaaccag attggttcgt
    33961 tggatgaaat aaaaatatcg atggaaattc aacggagtca ttggcacatt ttctggaaca
    34021 gagcgcttag acaaaatcga gcgaccgatt ccttccttca gcaacgcaac aattacatcg
    34081 ttacttttca cgatcatctt cttatcttgg atattcatct cttcaaaata acgctgcgtg
    34141 taatgaaaaa caccagagtt tgcttctctt acaagccaca atttgctttt tgggtcccca
    34201 gcgatgacta gctggtcttc catcaaagag tatctttgta cgccggaagt ctctaatggc
    34261 ttttcgataa aaccaaaatc ggattcatgt ttcgctactt gttctaatga ttcatgagaa
    34321 ttcgtgattt cgatctcaaa atgcacttta ggaaaccttt tgatcagatg tttcatcaac
    34381 tgaggcaaaa gatagacagc aaaggtgtgg gaagcaacga tccgacatac ttcttcttca
    34441 ttttgttcat tgagcaattt ttgctgagtt tcttcccatt cttctaacaa aaccagtgtc
    34501 cgttcatata ataagtcggc ttgcttagtt ggaagcatct cttttcttcc gttacgttga
    34561 aaaagatcga tattcaattc ccgctccaac tgtttgattt gattcgagac tgctggttga
    34621 gataaaaaca gtacttctgc tgctctggaa aaatttcttg tttcatatac tgctcgaaaa
    34681 gtcgttaata acttaaacat ggcaccactt ccataacttt ttatgataat tactataaaa
    34741 actatttgat ttaaatatac aaaaaaccat ctataataga aatgtacaac aaaacagttg
    34801 ctgatccaac tagtaactta gatgaagaca atcagctgtc tgcttgctcg taatcataca
    34861 ttcctattca ttttacaatg tattcgttca tcttggtact aaaatctatt aaataaaaag
    34921 gagaatatta tatatgaaga actttttgaa aattattccg atcccgatct gcgggttgat
    34981 ccttgggtta gcttcccttg gaaatctgtt taaagactat caccatgttg ctttaggcaa
    35041 tctaactggc ggtatctcta tgattcttat gatattcatt tttgttaaat tgtttatctt
    35101 attcgaacac acgaaacaaa cgttgcatga tccaatcatc gcctccgttt caccaacttt
    35161 tacgatgtca ctcatggtta tttgtactta ttttgtttca tatgaaagta ttgcaccaat
    35221 tgtcaaattc atttggctgt gcgctgttat cttccaagtg atccttgtct tttatttcaa
    35281 ttatcaccat gttatcaaag ctgatctttc aattgaagca atttatccaa gctggtttat
    35341 catttacgtt ggatttgggg tcatcactgt aactgccggg aacttcttcc cacttattgg
    35401 aaaaattttc ttttggattt cattgatctg ctatgcgttc ttattgccga tcatcatcaa
    35461 acgtgtcttt ttcgtaagaa atatggctca tccgacacgt ccgctgatta cgatcgttgc
    35521 agcacctggt tctctttgcc taacaggtta tcttaaaaac tttgctgaac ctaattttta
    35581 tcttgtcgta gcattgttcg ctttatctca agtattgtat ttcgttgtgc tgtctatgct
    35641 tccacgtttg ttcaagcttc gtttttatcc aagctatgca gcctttacat tcccgcttgt
    35701 tatctctgca acagctatat ttactactgt tcattacttc aacagtttag gtatctatag
    35761 tagcgtattg gatttcttaa aagttgcgga atgtctgttt gcaagtgtag ttgtcttcta
    35821 cgttcttgct cattacgtac gtttcttaat taaagaacat agcaaacatg gaaaatttgt
    35881 ttctaaaaaa atcgcttaat aatcgattca ataggttgtg aaaaagctgt tctgcatcaa
    35941 gtaataagaa cggccaaaca aaaacagctg ttcatgtttt tgtactggtt gggcttatta
    36001 ccgcagatgc aagcttttga acaccgttta ccaagaggtc gtaaaagaag tggtcagctt
    36061 caagaaataa gaaggaattt acgaaaattg cttctcaaat ttttgtgaaa tttcggctta
    36121 tttccgtaga agctacttct ggaacaccgt ttattcgaaa caagaggtcg tacaagactt
    36181 ttgtcacgac ctcttgttct tttgtcaaaa tactggttta gtgctactat gttcgagtat
    36241 gcttttagta tttattgacg aaaggaaccg atcaaatgaa atcattgtca catccaataa
    36301 aatctgtaaa ggattcagcg gtccgcgaaa tcttacccgg tttactgctt tcttttgcca
    36361 tcgctgcctt cagcaggctt cttgctattt atctgccaca gttaggtgga gcgactattg
    36421 ctattttatt gggtatttta ttaggaaata ctttttttaa acagcctgtt ctagcaatcg
    36481 gcacaaaatt tgctgaaagc aaactattag aattctctgt ttttttacta ggtgcaactg
    36541 tcacagctca aacgattgct caaattggtg taaaaggaat tgtttttgtg ttactgcaaa
    36601 tgtcagtcac tatcatcggt gcttacttga ttggtaaaaa actgcaattc agcgatactt
    36661 cttctttgat gatggctgga ggaaacgctg tttgtggttc ttctgctatt gcttcaatcg
    36721 ccccttccat ccatgcgaaa gaggaagaaa aaggacagat catcacacta gtcaatctac
    36781 tgggtactgt gatgatgttg actctccctt ttcttggatt acagttgttt ggtggaaatc
    36841 tcattgaaaa aagtgcactt ttgggtggta cactccaatc tgttggtcaa gtagtcgctg
    36901 gggcaagctt acttgacaat tctgttgtcg aattcgccat gctatttaag attctacgta
    36961 ttatgatgct cgttgttgtt gtctatctgt ttgaaaaatt catgcacaag aaacaaccag
    37021 ctctgtttga aacgccaact gatacgcaga aaaaacgaaa attaccgctt ccttggtatg
    37081 tattagggtt tgtgatcttt tgtttggtca acagcttgtt ttctttacct gtagttattg
    37141 accaatcggc acattttatc agcagctggt ttgagatcac tgctttagcg gcaattggtc
    37201 tgcgtttaga ctttgcaaaa ttcatgaaag aaggtacacg cttcttatct tatggattag
    37261 ctgtcgggct tctccaaaca gtgatggctt tactatttat ttggctgatc aaagtttaga
    37321 atgaacatga aaaaacagtt gtgattctcg catggaacaa tgtccgaatc acaactgttt
    37381 ttaattttgc agatatcctt ctaacaacaa caattggcgt ttgatttcaa ccccatctat
    37441 tgcgtttccc atatatcctg tcagttttcc attttgcccg atcactcgat gacaaggaat
    37501 aacgattggc aatggattgg ttcgatttgc ctgcccaatc gctcgcacag ctttcggact
    37561 atcaacagca acggctactt ctttatacgt tcggatttct ccataaggaa tggtcgacaa
    37621 agctttccag acattttgct gaaaaggcgt acctctcttt atagataaag gaacatcaaa
    37681 ttcttttctt tttcccgcaa aatattcttc aaactgttct tgtgtgcgcg ttaaaattcg
    37741 ctgattcgct gattcgcttt ctgaaattgg ctgaaaagat acagcagtca atccggattc
    37801 atctgcatct aaccataaaa agccgatagg tgtgtgtatt ttcattttgt ttgctcctag
    37861 tcaatagact ggaacttcct cctttttctc tatccaaaac tacttgccaa ctaataaaaa
    37921 ttgttcttaa aagtttgata aaccgaggaa acatggtaaa ctaaatacgt tagtttacaa
    37981 aaagaatacc tgttctttta cgtaaaatca aattttaaag gtgttattta aggtttatta
    38041 aattttgaat gtaaaccata tataaacata cgattgaaag gatagaaacg atgaaagtat
    38101 caattgttgt cccatgtttt aatgaagaaa aaactgttcc tctttttttt gatgaggttg
    38161 aaaaattcaa aggtgcccat gagttcgaat atttgtttat tgacgacgga tcaaaagacg
    38221 gtacgttagc agcaatcaag aagctagcct cagcttatcc ttatgtccgc tttgtctcat
    38281 tttccagaaa ttttgggaaa gaagcggctc tgtacgctgg attgcaagct tctacaggag
    38341 atttagtgac cgtgatggat gttgatctgc aagatccgcc cgaactgctt cctgagatga
    38401 tcaaccggat cactacttct gatatcgatt gtgtcggcac ccggcgttcg actcgtgaag
    38461 gcgagcctgc gatacgcagt ttctttgcga aaaaattcta ccagttgatc aataaaatca
    38521 gcgatacaga aatggtcgat ggcgctcgtg atttccgctt gatgactcgt caaatggtgg
    38581 atgccgtcct agaattaaca gaatacaacc gattttcaaa aggattattt agctgggtcg
    38641 gatttaaaac agaatatatt tcttatgaaa accgcgaacg tgtggctggc gaaacatctt
    38701 ggtccttctg gaaattattc aactactcga ttgatggtat cgtgaacttc tcggatgcac
    38761 cgttaacgat tgcttcattt atcggcgctt tgtcttgtgt cggttctggt attgcaattt
    38821 tgttcattat tttgcgggca ttgttgtttg gtgatcctac atcaggatgg ccttccatgg
    38881 tctcgatctt cctgttcatt ggtggaatcc aattgttatg tcttggaatc atcgggaaat
    38941 atattgggaa aatcttctta gaaacgaaac agcgtcctgt ttatatcata agagaaacag
    39001 aaaaagtgaa gccaaatgaa ttgaagcctc accaataata tacgtcaaat gaagtaaaca
    39061 tttttttaaa tgaaaaagga ctgtgacaaa agtcttgtca cagtcctttt ttccgaataa
    39121 atggtgttcc agaagtagct tcttcggaaa taagccgaaa tttcacaaaa atttgagaag
    39181 caattttcgt aaattccttc ttatttcttg aagctgacca cttctatcac aacctctttc
    39241 atatcttatt acttcttcat tgctgctttt agtgctgctg ctaatgggct ttcttctggt
    39301 tcttctgctt gtgcatattt tttcagcaag cgtcgttctt catgtttggt cattttcttc
    39361 ttctgctctt ttttatcaag caatttttct gtcgttccat cgtatttaca acggaaataa
    39421 gcaccgtttt taccttcgat gatttccatt ttccggtgac attgcgggca tcgatgatta
    39481 gagacttttg gatcttttct tctgcggtag ttgcaatctg aattggtgca gacatagatt
    39541 ttgccgtcac gtgtgttttt ctcgcgcaga ttggccccac attctgggca tttcttttgg
    39601 gtaatcgaga aatcttgata ttcttgtttg cttgatttga tctcattcac caagcgtttt
    39661 gtttcttttt cgattccatt caagaaggtt cctgcttgtt tctttcctgc agcaatagct
    39721 tcaaggtctt tttcccagct ttctgtcaaa tctggtgtta ctaaagaggg atttaccaat
    39781 actaataatt gcttaccttt aggagatact tgcagtcctt gaggggtacg ttccatcagt
    39841 tcagatttga ttagtttctc gataatctct gcacgcgtag ctggggttcc cagactgtat
    39901 ttttccattt gaccaagcaa gcttgcttct gacaatggtt taggcggtgc agatagttct
    39961 tttttgatgg cgaaatcggg attgattctc attccttttt cccatttgac tgtttccgtc
    40021 tcagtttcag tttcgccttt ccatcctgct tggacgacac gattttgccg aaaaatgaat
    40081 cgttctttac caaattcaac cgtaactttt gtttggctga ctttatgggg ttgagcaaac
    40141 agtcctaaaa aacgagagac aatcatttga tagatttttc gctcttcatt acttaatttt
    40201 tcataacgtg ctctgttttc agttggcaaa agtgcatggt gatcggtcac tttactgtct
    40261 tggaatactt ttgtctgttg gacgatggct ccgtttttca aatactgctt gacctcagga
    40321 gcaaagtcgc tgactgcttg caatcgttct ttcatcgtac ttttcatgtc atttgtcaga
    40381 tatttgctgt ctgtacgcgg ataagtaacg atcttatggg tctcatacaa actttgtaca
    40441 agacttaatg ttttctttgc agaatagcca tagcgttgat tggcttctct ttggatctct
    40501 gttaaatcat aaggcaatgg cgcagattcc gtttttaatt tttcttggac ttctgtgaca
    40561 gttcctttgc ttgtactgat caattgaaca agtttttgtg cttcttcttg tgtttttaaa
    40621 gcaaattgat ttttttgaag cattttggct tgttcttttc cagcttgcaa cgtgatcgtg
    40681 aaatacgttt gtggacggaa ctgctcgatt ttcttttctt ggtctctcac taatgctagt
    40741 gtcggtgtct gcacacggcc tgctgataaa ttatccgcgt acttcacagt taaggctctg
    40801 gtcacattca atcctaccag ccagtccgct tttgcccggg caagagcaga ttcatacaat
    40861 gcatcatatt ctttcgcagg tcttagttgc ttgaatccag ttttgattgc tttatctgtt
    40921 tgagaagaga tccataaccg cttcactggt ttattgaaat gcacatactc taagatccag
    40981 cgagcaacaa gttccccttc tcttccggca tctgtcgcaa tgactgcttc tgagacatct
    41041 tttcgctgag ccagctgctt gattgctttt aattgatgtc ctgttttagg aagtggtttg
    41101 attcctagtt ttttagggat cattggcaac gtgtccattt gccagctctg ccattcctta
    41161 ttcagatctt ccggcatttt caatcctaat aaatgaccaa gggcccaagt aacgatcacc
    41221 ttgggtcctt cataataatt tttgtgcttt tgattagcac caagcacctt gcttaggtct
    41281 ttcgcaacgc ttggtttttc cgctagaatt agttgtttca taaaattcct ttctgctttc
    41341 tactgtgatg ggctgatgat ttttcaacaa cgcaagtccc ttgtattgct gtaaatcatc
    41401 gtcacactct tcacaccagc gctcatctcc gtcattccaa aaggcgctga gaaagttact
    41461 ttttgcattg atatattcat aattttgatg gatttcgttc cattgttttt cgtacgcttg
    41521 tcgtgcttct tcgaaagact cgaatgtttc ttcttcttca atatcttctt cccagtcttc
    41581 aaaaaaccac caaggctcat tgtccccgaa catggtaatt acttgataca tactcgtgct
    41641 ccttctttca gcttttctag actcatctta gtcacttttc aagaaagttg caagaatttt
    41701 ctcttataaa agggtcattt aatgaacatc ttaaaattgt tacaaatgaa tctgattgtt
    41761 taaggcaaag tagcgataaa gttattgatc atccaaaaat agctgtcttc tggatcgatt
    41821 gttggttctt ttgtaaagta tcctaaaaaa cgtaaggaaa gataaccgtg gatcatacta
    41881 cgaagttccc tgcttcgatg aactttttct tctttcgtta attgaaaagc ctcaaatatc
    41941 tgcaaaatga tctgattcgt ttcatggatt ccatctaata aaacagcttc attggtatgc
    42001 ggtacactga tcagtaactc atacactgct tgatttgaaa aagcaaagga tcgataagtt
    42061 tctgcataga tctgcagtgc ttcctgacca ctttttccca caagagcccg tcgcagctgg
    42121 tcattaagtt cctgcagaag tttcgctgtt agcgctgttt tgacatcacg aatatttttg
    42181 aaatggttat acagcgaggg agccttgata tccaagcgtt tggctaaatg ctgaaaggtt
    42241 atttgctgaa catccatctc ttctgctagt tctcgaaagc agtcgatgat tttctcttga
    42301 gacagatttc tttttttcat ttccatgttt cctctcataa aataaatcct tcactctttc
    42361 agtttaccac gaaaaagaaa gagaaaaaag agactttcat tgataaacta catattgtag
    42421 tttataataa agagctgtag atgaaaattt tcagaaagaa ggagtctaat tggctgcaag
    42481 aataaaggaa aaattattta ggaaaagaga aacttgggaa caaaacttgt ttgtcttatg
    42541 gtttggaaca tttatggctg gtatcggatt tagtttagtc atgcctttta tgtcacttta
    42601 catagatacg ttaggtaatt atagtacgtc acaattgaac ttttggagcg gattgacttt
    42661 ttcatctact ttcttggtga ctacgcttat ctctccttgg tggggaaaat tagccgacca
    42721 aaaaggaaga aaattgatgc tgttgcgtgc ttcattagga atggcaatcg tcatttcttt
    42781 gatgggttgc gtgactagtg tgtatcaatt agtcgcattg cgtctgcttc aagggatttt
    42841 ttctggttat atcagtaatg ccactgccct tgtcgcaact gggacgccaa aagaaaaaag
    42901 tggtcaagtt cttggaacct tagcaactgg ttctgttaca ggaacattac ttggaccgct
    42961 tcttggcggg atctctgctt cagcgtttgg ctatcgccct acctttttca ttacagggat
    43021 catcttattt ttcgtcttct tgttgagtct gtttttcgtc catgaaaaat ttgtcccagt
    43081 gaaaaaagaa aacatggttt ctgccaaaca gattttcaaa gacttgaaat atccacacgt
    43141 cgtcatcggt atgttcgtca caacgatgat catccaagca tccaacaatt ccattagtcc
    43201 aatcatcagt ctgtacattc gccaattgct gcatggacat gggaatgtta cgttgatcag
    43261 cggaatcatt gcttcgatac ctgggattgc cactttgata gccgctccaa gatttggtcg
    43321 cttaggtgac aagattggga gtgaaagaat acttgcgatt ggtttgggtt ttgcgattct
    43381 ggtttatatc ccaatggcat tcgtcacgaa tgtttggcaa ttagctgcct tacgtttttt
    43441 gattggtatc tctgatgctt gtctgctccc tgctgtccaa gcattgatca caaaatattc
    43501 gcctcatcaa gctgctggac ggatcttcag ttataaccaa tctttccaag caactggtaa
    43561 cgtagtaggg cctatgatcg gctccagtgt ttccagtgca tttggttatc gcggcgtctt
    43621 tctttcgact tctcttcttg ttttggtcaa cttcttgctt gtacgacaca atacacaaga
    43681 gatccatcag caagaaactg cagaagaaaa agcttcagga gtctccatag cttcagggca
    43741 ctctccttct catagacaat aagcgtaaat gaaaaacact gcttgaacag ttgtcacaga
    43801 ctgtccttgc agtgtttttg tttaggcctg ttttttcaag aactcagata agaggaataa
    43861 tcccttttcc aaggtttctt ttttacaaca gtaacctagt cgggcatgct tcggtaaatc
    43921 aaaggcactt cctggtacta atagtactcc tgtttcttct aataaattga tacaaaatgt
    43981 ctggtcatct tcttcgatgg ctaatttaat gaaagaagta gagacgtaat tgggagcgac
    44041 aagttcaact ttcggttcat tggctaccca ttgttttaaa atcacaaggt tctctgtaat
    44101 gatctttttg tttcgcgcca atattttttc tttattcttc aatgcatgta cagcaagatc
    44161 atctgacagg actccgccgc aaatcatcgt gtagtctcga tactttcgaa aaacttctgc
    44221 caactcaggt ccagtagctg tccagccaat acgaatacct ggaatggagt aggttttgga
    44281 tagggaattg gttgctatac ctttttcata gacatctacg atcgacaaga attcaccttt
    44341 atccgttaaa ggcgcatata cttcatctat caatacatat gcatctactg tacgagcaat
    44401 ttctgcgatt ttttctaaag ttttccgatc tagcaatgtg cctgtaggat tgtttgcact
    44461 attcaaacag atgatttttg tttcaggttt gactaaggct tctagctgtt ctaaatcaaa
    44521 ctgccaatct tcttcttcct tcaaatgaac aaagtcaaca gcggcaccta aagatttggg
    44581 gatgtcatat aattgctgat aagtaggaag catcgaaaca acatggtctc ctgcttccac
    44641 taacgcgtat agagctaaaa gattagcacc agtcgctcca ttcgtttgta agatgttttc
    44701 cggatcgacg gtttgataaa gagaagcgac ttcttgtttg aaaacatctg atccttcgat
    44761 ccagccatag tccaatggtt cgtttttgcg tttttcgaaa aatttactta cgctagtccc
    44821 atctaagcca acgagttcgt ctaatgtcaa tgcttcgatc gagctttgtg caatatcata
    44881 taccgctttc ttttcccatt tatttagcca ttcttctaca ccgaaatttg cgattttcat
    44941 gtttctttcc cccttatatc ttgatccagc ctacagcaag caacccgatt gaaagcagtg
    45001 cggccacaca aatcagccca atcattactt tttcttttcc cgtaatttga tgtttggttt
    45061 cacgacaagc gatccagtag aagcaaaaac caggaagata ggcaatacta cataaaagga
    45121 cataagaaaa tcctgctaaa atgatgccca tcaattcaaa aactacagca atcccaccga
    45181 tcactacttg ttttttgatt ccttctttta aagaaaactg gacttgatag atcccgacaa
    45241 gtagataaca aatcaaaatt gccgctgtac ataaagaata ggcaaattga taggcataat
    45301 cagtaactaa gaaagtcaat aagaatagat tagtcaagat tgcagtaaca actaacgaat
    45361 aagttggggc atttttttta ttcgtttttc cccaaccttt cggcaacaga ccgtctcgag
    45421 ccatcaacat cgttgtttct gctgggagca tcgtccaaga caaccaagaa ccaatgatcg
    45481 aaataatcaa gccgatattg atcagcgctg ctccccaatt tcccacgatt ccttttaaaa
    45541 tatttgccat agcaggttgt gaaatagttg ctaactcttc ttgagataag acgccgtatg
    45601 gcaagatcga agcaaggata tagataaaca ataaacaaag cagaccaatg atcgatgctt
    45661 gctgggcttc tgaacgtttc ttcgcgcggt tggctaaaac acttgcgcct tcgatcccta
    45721 caaagaccca catcataacc atcaaacaac ctttaatctg caaccagatc gttccttgct
    45781 gccctgttcc attcactaga ttatcagata cgttacccca aaaatcagca gtgaatatat
    45841 tcactttaaa tgcgataaat acaaatatta aaaataggaa taatggcact aatttacaga
    45901 tcgtcacgat tgtattgatg acgctcgctc cttcaactcc attgtttact aataaagtca
    45961 gaccccaaat aaaaatactt gcaaataaaa tagaaggaac attttgtcca cctttgaata
    46021 tcgggaaaaa ttctcccatg gcgctcatca gcatcgttgc aaaagcaaca tttcccagcc
    46081 acgcagacaa ccagtaaccc caaccactga tgaagccacc taatttacca aatgaagctt
    46141 ccgcgtaacc gaaaatacca ccatctagat ctggacgctt ttctcctaaa tgattcagcg
    46201 ataataccaa agctaaaata ccaatcccaa cgattatcca tgaaaggatc gctggccctg
    46261 gagctgcaga actagccaga tcacttgtga tcccaaacac accgcttccg attgacgaac
    46321 tgacaaccag agcaaccagt ccccatttgc taatacccgt cgatttcttt tccatttcca
    46381 tcaccctcac ttataaaatt gaacaaatca cttgcaaaag attcccttct attttgcaac
    46441 tgctcttgct taacaaaaag caactttatt catattattg gatattatga actttttaca
    46501 caagtatttc aagtataaaa tgaataaaaa ttaattttat tgcaaaaaaa cagctatgct
    46561 atccaaaaga aaaggtgttt cttttgttag ccatagctgt tttgattcat ttaatatcgc
    46621 ttaaacgtat tgtaaaactt ttgtttcttg atatgcgtgg tcgatcaaac caccacccag
    46681 acattccatt ccatcataaa atacaactgc ttgtccagga gtgattgcac gtacaggttc
    46741 gtcgaatacg acttctgcac gattatcatc caataagcga actgtcacag gaacgtcttg
    46801 ctgacgataa cggaatttcg ctgtacactt gaattctttt ggcattggtt cattcgtcgt
    46861 aaagtggatt tcacttgcat ccaagcttgt ggcatacaat gcaggatgat ggaacccttg
    46921 ccccacatat aatgtgtttg tcgctagatc ttttcctaca acaaaccagg gttcttgcga
    46981 atctcctccg ccaccgatcc ctagtccttg acgttgacca atcgtataat acatcaagcc
    47041 agcatgttgt cctttgactt caccatcaag agtgaccata tttccttttt ttgctggcag
    47101 atagttgctc aaaaattgtt tgaagttctt ttcaccaata aagcagattc ccgttgaatc
    47161 ttttttctta gcagtcgcaa ggcctgcgcg ttcagcaatt gcccgtactt ctgatttttc
    47221 catgccgcct agagggaaca tcgtttttga aagctgttct tgtgataatt ggctaaggaa
    47281 gtaagtttga tctttattat tgtctactcc acgaagcatg tggaccacgc cgttttcatc
    47341 gcgagtgact tgcgcataat gtccagtagc tacataatcg gcgccaagat ccattgcata
    47401 atccaagaat gctttgaatt tgatttcttt gttgcacatc acgtctgggt taggtgtacg
    47461 tcctgcgcgg tattcggcta ggaaatattc aaatacacga tcccaatatt ctttttcaaa
    47521 attcacagag taataaggaa tcccgatttg agcagctact ttcgctacat ccttataatc
    47581 ttccgtggcc gtgcatacac cgttttcgtc cgtgtcatcc caatttttca tgaatattcc
    47641 gatcacgtcg tatccttgtt cctttaacaa aagtgctgtt acagatgagt cgacaccgcc
    47701 gctcatccct acgacaacgc gtgttttgct gttgtctgtc atgatatcac catcatttca
    47761 attagattct gaaacatcta cgagttgaag gtcgcaactt ttcagtattt tacattatac
    47821 gtcatatttc tgaaaatttc atcccttaat tatcaagtcg taaaaatact gttctactgg
    47881 acctattcag tacacaaaca tgatagtcaa ccaaaaaatc actcatcttt tgagcattcg
    47941 atataaaaaa ttggcatact cataaaaagg gccagccttt cggcaataag gaataatttt
    48001 ataaattgtg aaaaactatt tttcaaaatt gcttcttatc gcttaaagct gcacgtctca
    48061 tttacaacct tttcttttta gatgttatga gttgctcaga taagtgattt tgtttactct
    48121 aagaaaaaag ggaggcaaaa gatacatgaa ttactttatc agtgatatgc actttttcca
    48181 tgaacgctta ttaggaaaaa acgactttgc tccgcggctc tttgcaaatg tggatgaaat
    48241 gaaccaacag ttgatcacta gctggaatgc agtaataaaa gaaaccgacc atgtttatca
    48301 tctaggcgac cttgctatgc atccgcaata tgaaaaagca aatgcagaaa ttttggaact
    48361 ggtcactcaa ctgcaaggaa caatccactt gatcaaaggg aaccatgaca gtcgcgcttt
    48421 tttccgttat ttagaaaaaa atgatcctag gcttactgac ggaagtccca aattttattt
    48481 ttatgatgta ggtgccatcg ttaaattcga ccatcaacaa tattacttga ctcattatcc
    48541 gatgttgctc gggcctaacg acactatccg caatcttcat ggacatatcc atcattacag
    48601 cgtacctatc gagaacgatg tcaatgtagg cgtagacgca ccggaaagag aactcttaaa
    48661 ggaaaaacta ccatttggca ctccgttatc tgagcaacaa atcaaagaaa tctatgaagc
    48721 aaagaggaag tacgataggt cgtgaaaaaa ctgccctata tcaagtatta aacaaataaa
    48781 gataattact catatttttc atttgagtag gcttattgcc acaggaacat taggatcaga
    48841 aatggagttg taacaagact tctgtcacaa ctccattcca tactattcgt ctttttgctc
    48901 atggtgttct tttaccagtt ttttctgtaa ttctttatca taatttcggg cagctgacgt
    48961 taaaaataaa acgattccgc ataataaaat cccgattccg gaaaacaaga acattttttc
    49021 tacccctaaa cgatcagcta atggtcctgc aaataataat ccaattggac ctgccaggtt
    49081 catcaaagag ttgaagttcc ctaagacacg acctaaaaca ttcgattcat aactctgctg
    49141 gatcattgcc atcagcagtg tattgaaata tggcgttgca caacctgctc ctgcattcaa
    49201 gataagaaag tacaagaacc cttgactatc gtttggaacc aatccgcttg caccgatcgt
    49261 caggcccata atgatgtagg ctataataat aggtttcatt cggtctttcc atgttcctat
    49321 aaaactgatc agtgcaccgc ctaagagcat tccgactgcg tagactactt ccactgctcc
    49381 cgcctgtcca acggaaccac caaagtaatc tagcgtcatc aatggataca gactgattgc
    49441 tggcatgaac aacagcatca caaatgcacc attgatcgtt atgtaccata accctttatt
    49501 atccatcaat tgctgcagcc caaattttgc atctttaaaa atagtaagcg gaacttccaa
    49561 tatttcagga gaaacttttg ggatcttcac aaaaatcaat aagccgacac caaaaactgc
    49621 ccccaataca tctaataaaa taaggtaatt gacaggaacg actgaaaaca aagccgcacc
    49681 tagagctggc gcaatgatga aattcgctga ttggaccatt cctaactgtc cattcgtcct
    49741 tgttatgtga gaagatggaa cgattgtcgg cataatcgac tggatcgttg gcatttggaa
    49801 tgtttgtgcg accgaacgca taaacaaaga cacaaaaact agccaaatcg ggaaggattc
    49861 tgaaatcgtt ccgactactg ctaaaataag cgcgaaaatc gctacaataa tatccgtgac
    49921 aatcaaaaga gcttttttat cccagcgatc cactagcggt cctacaaatg ggcttagtaa
    49981 aaccatggga atcattccta gtaaagtagc aaaactcaaa attgtcgccg aaccggtttc
    50041 tcttgtcaaa taccagatga tcgcatattg gacgaccata ctagtgattc ctgacaaaaa
    50101 ctgtcccgat aaaaagaaca aataatttct cttccaattc gttaaaacga ccgactgttc
    50161 attttccata aacatccctc ttttcttttt cattttgtat agcgtttgca caacaatcat
    50221 tatacgggat tcttttttca aaaaatacct ttttccctaa ataacaatcg tttcaattta
    50281 aatttcttta cttagaaaca ataaatcagc aaaatattaa aaataacaac atgtgttaaa
    50341 tttaaaaata aaaaagacaa ctaatttgcg tcgtccttac aaagttagtc atctaacaat
    50401 aggccgtttc aaaactagtt gtctttttat atccacagat cattcgactt tttcgaataa
    50461 cccacggcta atcatcccat ccatcagaaa ataaaattta tcttggctca ttttctgttt
    50521 tggatctttg aaaatattga ctgctttcaa tccatttgct gtagtgatcg acattttcaa
    50581 tgtttgaata tcttttgata cagtgatttt taatttgaat ccttctttgc tttgcggcgt
    50641 ggcatctaat ggtcggatca attgataatt gcctccgttt gtttctgtaa atccattatc
    50701 gcgcaatgta tatctttttg catcaggatg caaacgatag ctaattggtg cgcccagtac
    50761 cgttgctgtt gtttcaaatg ccatgatttt cacctcgata aaattagttt ctctttatta
    50821 taaaagttta tcctgatttt tactaggttt ttcagttaag ttccctaaaa aatgaaggcg
    50881 ttctctcaga catctgttca tataagaatg acttcactag ttattttttg acagcacgaa
    50941 ctaattgatc aaggaaatac tggatgtcgt cttcggtatt tcccaaacca aagctgatac
    51001 ggatggattc ttttagtatc ggtgtatctt ctccatacat tgcttctaat acgtgtgaag
    51061 gctcgatatt tcctgctgta caagctgaac cagtagaaat agcgacccca ttaagatcaa
    51121 gcttcatcag tagcaaatca tttgcttcgc caattaagcg aagattcaac acatgaggga
    51181 gtttattcgt taaatcacca tttacttgat aagggatttc gtttgcttct aatgtatcaa
    51241 gaatcaattg ctggaatcct ttatatttgt tgttacgtgc ttcacgttct tcaggtgaca
    51301 gcagttcaac tgcttttgcc ataccccaga tccctgctaa attttctgta cctgcacgcc
    51361 gcttttcttc ctgctccccg cctaaaagca atgcagggat atttactccg tctcgtttat
    51421 ataagaaacc gacgcctttt ggcccattga ttttatgagc agagatactt aataaatcga
    51481 ttcctaattc ttctggatgg atcgtttggt ttccgtacgc ttgtaccgca tctgtatgga
    51541 aataagctgg atgatccgct aaaagttcac cgatttcttt gattggcatc aaatttccga
    51601 tttcattgtt cccgtacatc acagagacca agatcgtatc ttctcgtaac gcttttttga
    51661 cctcttcgat cgacagattc cctttttcat ctacaggcag atatgtaacg tcaaacccct
    51721 ttgtctctaa atatttcatg gtattaagaa cagcaggatg ttcgatagct gtagtgatta
    51781 gatgtctgcc ttctttttga cgcgagaacg ctgtttctaa gatagctgta ttatcccctt
    51841 ctgttccccc actgttaaag atgatctcgt gaggttttgc ttgcagactg tctgcaatga
    51901 tttgtcttgc tgtttccaat ttttcatgcg cgtggcgacc aaatccatgt atgcttgaag
    51961 gatttccaaa cgtgtcttgc atgattgccg tcatcgcttc aattacttgt ggatgcatgg
    52021 gggtagttgc cgcatgatcc agataaatag ttttcacttc attcatccct tccaaattat
    52081 tgctaggcac attctagcat aaaatagcga acaaaccaaa gaagagctca tttttgtcta
    52141 gaggacgttt catgggcata gaaaaaagga gctgtgacaa aagtcttgtc gcagctcctt
    52201 gaagctgctc acttctgtca caacttcttt ccctcttttt tttgtttatt cgaattcttt
    52261 ttcttccaga cggaataacg gactcatcgg tgtattttca tggatgcgtt tgaccgcttc
    52321 acccattaat tctgaacatg taacgattgt taagttttct ggatgacgat tttcttctgt
    52381 gaaaacagaa tcagtgatac aaatatcttt gattggtgca ttgtctaaaa tacttttcgc
    52441 atgatcggac aataatccat gtgacgcaca ggcatatact tcttttgcgc cgttttcttt
    52501 taatacattt gctgctcgtg caagcgttgc tcctgtgttc aagatatcat ctaccatgat
    52561 acatgtcttt ccttgaacat caccgatcac ataaccaccc tcagttgaag catcatctgc
    52621 atgatctacg atggctaatg tgctgttcaa atattctgaa agactacgtg cacgctgaac
    52681 accgctgttt tttggcgaaa caactacgat gtcatctccc gtcagaccta attgacggta
    52741 ataatgagca aacaacggca tcgtaaataa attatctaca ggaatatcaa agaatccttg
    52801 tacttgaacc gtgtgcagat ctaaagtcag tactcgagtt gcccctgctt cttcgatcaa
    52861 gttagcgatc aatttcgcag tgatcggttc atgaggtttc gccgtgcggt cttgcctagc
    52921 atacccatag taaggcaata cgacattgat cgttttcgca cttgctcgct tcattgcatc
    52981 gatcatgatc agtagttcca tatagtaatc attgacaggt gcattcgttg attgaacgat
    53041 atacacatga tcccctcgaa tactttcttc gatattgatg gaaatctcgc catcactaaa
    53101 ttgcttcacg acgcttttac ctaattctgt tccgaacact ttcgcgattt tttcagctaa
    53161 tggacggttg ccattcaaac taaaaatctt caacgtgtca tcctgatact tattactcat
    53221 gtagtcctcc ccaaaacttc tctattcttc gatagtttaa catatttttc caagattttc
    53281 tgttaatttc agcaaattct taaggaagtg aaactgttcc gttactccaa ctggcaggaa
    53341 tgactttatg ataatcgccc cagttgtcgt gtactttgta ataacgttct cctgtttcag
    53401 tttcaaaata agcgtacgct gtcacccaat gattgccata tgtactgcca agtactttca
    53461 aaataccaat catcacaggt ttgccttcac gtatacgttt tgtagctcgc tgccatgaac
    53521 ctagaagagt tgctcgtgca cgctcatgat tgccattctt ctttaaaaaa ctagaaatcc
    53581 ctgtactaac ctgaaaagga atcgtaggaa gtcctagtgg ttggatctgg ctacgcaatg
    53641 ccttcgtcaa aaccaacgaa tcagccgtat ttttcttgcg aatctcattt ggaagcatcc
    53701 accccttacg atagtcttga taataggcaa ggagaactgc tgccgcgtaa gtaccacaaa
    53761 gatagcctga gggggtagcc catttcttat acctcaaaaa acgttcttct ggcaatccca
    53821 cccagcaatt tgcgagttcc tttcctgacc ttttttcttc gatcaaaacg ggaatatctt
    53881 cttttctgtt gatccatcta gataactcga ttggctcttc attgatcagc ttccattttt
    53941 tacaagaaag accctcttga taagtatatt ttgctggaga atattctacc ggatgtcctg
    54001 attgatcgat aatcacataa ctttgatctt caaaaaccag agctaaaaaa agcaatttac
    54061 tttttcttga ctgcagctgc tgagtgctgg ctaatttttt aattttttta tctactttga
    54121 aatataaagg tttatccact acttgattca gttgggatcg cctccttttt ttcattataa
    54181 gtgaaggatt gaaaaaaaca aatcagtttg attgttcgaa ttttcaattt tttatgttct
    54241 atttgttaat tccttcattt tgtaagataa tgggcacacg aaacaaaaaa ggagcgatcg
    54301 atgaatgaac aaagaacgat tgaaacaaga tttctatgaa gcagtcaatg aagaatggca
    54361 aaaaacagca aaaatccctg cagataaacc agctacaggc ggtttccaag atttagttga
    54421 cgggatcgac caacttttga tgggagaaac agacgatctg cttgcccatc cagaaaaagt
    54481 gtcttcagaa aaaatgaaac atttccttgc atattatcaa ctggcaaacg attatgaccg
    54541 aagaaatgag ttgcatgctc aaccgcttca acctataatc gaaaaagttg aatcattgca
    54601 gtctttcgac gaattgaata agcaatttcc agaatggctg ttggatacat taccattgcc
    54661 atttaatctg gatgtagatg cagatatgaa gaatgcgcaa acgaacgcct tctttgctta
    54721 tccgccttct ttattccttc cagataagac gtattatgca tcagaccatc ccaacggtgc
    54781 acaactaata ggcgttttct ttgatatggc tgttcagtta ttagagcttg ccggcaaaga
    54841 aaaaagtcag gcagaagcaa tcacggaaca agcagtgcaa tttgataaat tgattgctcc
    54901 tcatgtaaaa agtgcagaag aaaacgcaga ttacagcaaa atgtataatc cgcaatcttt
    54961 tgatacattt attaaataca cagataaact ggacttgaaa aaacttgtca cgggtttgat
    55021 tgggacaact ccagataaag tgatcgtaac tgatccagtg tacttcgatc atttgaatga
    55081 catcctgaca gaagctcatt ttccgttatt caaaagctgg atgatcatta aaacagtacg
    55141 ttctcttagt ggttatctat cagaagaatt ccgccaagtc agcggaatct attctcgcgt
    55201 attgtctgga acagacgaag caatgcctca gaaaaaagca gcgtattacc ttgcctctgg
    55261 acaattcgat caagtagttg gcgattacta cggaaaaaaa tattttggcg aagctgctaa
    55321 aaaagacgta gaacaaatgg tgaaaaaaat gatcgccgtt tataaaaaac gtctagaaga
    55381 aaatgactgg cttggggatg caacaaaaga aaaagccgtc ataaaattaa ataacttagg
    55441 tatccaagta ggctaccccg ataagatccc agcattattc gaccagttca aaacagtacc
    55501 tgcagatcag ggtggtactt tgctttcaaa tactcttgtt ttcagcaaac tcacattaaa
    55561 agatcgtttc agcaaatgga acaaaccagt ggatcgttca gaatgggaaa tgagtgctga
    55621 cacggtcaat gcttattatc atccatttcg gaatgtgatc gtctttccgg cagcgatcct
    55681 tcaagcacca ttttacagtc tagaacaatc aagctctgct aattatggtg gaatcggagc
    55741 tgttatcgct catgagattt cccatgcatt tgataataac ggcgctttat ttgacgaata
    55801 tggcaacttg aacaactggt ggacagaaga agatcttaca caatttcaaa acaaagcaca
    55861 agcaatgatc gaagaattcg atggtctgcc ttttgctgac ggaaaagtaa acggaaaatt
    55921 aaccgtttcg gaaaatattg ctgatgcagg cggtctaagc tgtgcattgg aagcagcaaa
    55981 aacggaatca gatctttcta tcgaggaatt ctttgtcaat tgggcaacga tttggcgtac
    56041 aaaagcaaaa aaagaatacc aacaactttt actgcaaatc gatgtccatg cccctgctaa
    56101 actccgagca aacgtgcaac caaaaaacct tgacgaattc tatgaaacat ttggtatcac
    56161 ggaacaagac gctatgtatc tagcgccaga aaaaagagtg cgaatctggt aagaggttgt
    56221 gccagaagtg gtcagcttca agaaataaga aggaatttgg gaaaatcgct tctcaaattt
    56281 ttgtgacatt tcggcttatt tttcgaagaa gttacttctg gaataccatg tattagaggt
    56341 tgtgaaaaag ctgcttagtt tcaagtagta agaaaaattt tgtgaaaatg gctttccaca
    56401 tttttgcata aatttgactt actaccgaga aactggcttt tgaacaccgt ttatcgagag
    56461 gttgtgaaat cagcgtcctg acctgagtat tagagaaaaa aacggaaaaa tagttcctca
    56521 tattttgccg tttgttgagc taataccgag ggtcagctga ttgaacaccg tttagtggag
    56581 agattgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaatcaaa agcagcaagg
    56641 agaacctcat ctataaaaag atagaaggaa gtgagacatc tattggtctc atttccttct
    56701 atttttactt tcctcagtca attgttttac atcataaaag gagaaattcc acttattttt
    56761 ttcgctgttt catgacataa acaactacac cgattaacaa aattcctcca gctaatgcta
    56821 gcaacgggtt attaaattct cccgtttttg ggagtccttg agtgccattt ttttcacttt
    56881 cttttgctgt cctatccgga tgagaaggtt ttccatttgg ttttccattt ggtgattcat
    56941 ttcctggatt ttctctttct ggtttgtcat ttcccggggg cacatcggca gtttctcgca
    57001 cagtgatcgc tttttgctgg gtaacagatt ctgtatgagc agaccatttt tccccatcaa
    57061 atatttccga acgataagtg acttctagcg tatattctcc ttttgaaggt gctgaaaaaa
    57121 tagcggtatg attagaaaat tgagcacttg actgtgtttc aacgatttgg atcttttctg
    57181 ggaaataacg catatcttca aagacaggcg ttccttgatt tggtgtgaaa gttgacacaa
    57241 aaactgtaaa aggcttcagt tcaatgatat ttccttctgc attctccgcc acaccatttg
    57301 cttcttgtat aataatcgga ttattttgtt catttggttt tgtctgattt ggttcttgta
    57361 cgattgcata ctctggatat tccgaagacg gtgaggtttc tccgtcaaaa atagcaccta
    57421 cagataatgg aagaccatcc actctttcct tttctgtttg acgattcccc ggtttaatct
    57481 gcatcagtcc atgaacatgg atacttccat tttcatagcg cgtaacaggc tgctgacctt
    57541 ctttcgaaca tgtatttaga gactcgatcc aatcttttga tatggtatgt ccaagagtat
    57601 tttctgattg tttctctcgt tcattccaat agtagttcaa cgagtggtag atttgatctt
    57661 cgttttgatt caatgggcgg atctgctctc tcatctcaag attctctgtt cggaaagata
    57721 agataccaga agcatggtag tctgtgtttc ctgctgaaga ggtataaaga gccacattat
    57781 atgaaccgtt attaaaactt gtactgctat tgacgataat atctgttccg ctattggaat
    57841 cgattccttt cgcaagattt tcgaaagaca aactattgat caattcatga gggcccgtta
    57901 aagaagaacc gcccattttg aatccattac cgttaccttc tccctcaatt cctggtaccc
    57961 agccgtttcg ataagcaact gagtttttga tgattacttt tccgatcgaa cctgtttcat
    58021 ttttagcaaa aaggtcccaa ccgtcatctg cattatgata cgcgatacaa ccgtcaaata
    58081 catttccttc tcctattgtc agtttggccg caaatccatc ggcatcttca aatcctggat
    58141 cggcattttc aaaagatgta cagttcttga ctaagttatg cgcgggccat gcttcgaaag
    58201 gatcatttga gctaccgctg atttggattc ctgtatttcc attccgataa gcatgaatct
    58261 cttcgatcaa attatgattt ccagaaatct gtaatccttt ttgcatagct gcactatttg
    58321 taatgtcaaa ccctcgtaaa ccccagtagt gactgaacag tgtcatccca tttccagttc
    58381 ctttaaaatc aagtacagga cgcttgtttt ctggattttt ctctgcaatc aactgaatcg
    58441 ggttttctct tgtcccgtta acgccttttg gaatcgtcaa tcctctttcg aaggaataag
    58501 ttccaggcgc catgacgatt gtctgcccag catatgcgta tctcaatgct tgtgtcagag
    58561 ataatggatt ttgtctgctt ccgtttcctg catctgaccc ttctggtgtt acataaactg
    58621 tcgaatattt aggtttacgg tagtccactg tatgaagaat ctcttttgtt tcataactag
    58681 tcatctctac gtattcttct ggcggatagt ttttatctgg cgtaaaactg aaagtaaatt
    58741 cgttcgttcc ttccatcagt tttgtctgat aatcaaattc ccgattcgca gtgatagcca
    58801 agttttttgc gttcttaagc acctctcctg ttgctttatt tttaattgtc aataatccgt
    58861 cagcatttgc tctaaaggac atagtatgat cttggtttcc tgaatgatta ctagaggtca
    58921 cagtgtaaat cggatcaatc aagcgagtag gtctttcttg cccaggagga tctgtcgcag
    58981 gatctgagta agcaacttcg attccttcta ccttgatcgt catattcctt gctgcagcaa
    59041 atcctgcata aataaccgat tcatctgaag cgtataattt ttcccagtca tacatgatgt
    59101 cagaagccat ttcttctcct gtttcaggat cgtaataata tgcctctaaa ccagtattcg
    59161 tttttttcat ctctacgtcc agtttagtaa tcgagttcgt ggccggaaac agattcccat
    59221 gaccgtttcc gaatatatta taagaacctg tttctttttc caagaaccct gctgaagtct
    59281 ctaaaggtgt tgtttccact gagacactcc caggagctgg cgcagcttgc ggatcttcag
    59341 atgatattcc tgtgattgcc cgtgtcccca atccaagtcg catcgtatat ttgctgccgc
    59401 tcgtgttgac cacttcttgt ctatccgagt cccagacata ttcgatccga ctgcctagta
    59461 tggcaaatga atttgaataa aatgcctgcc caaacaaatg attttttggt actgcgtctc
    59521 ttaccattaa agcaaatcct tcttgggcat tcgtataggt ccaagattct atttcgatcg
    59581 tcgcccgcat cctaaagttg atgtctttgg ggattgcttg ataataatag gtcattccat
    59641 ctgatccgct tgactggaat tttccgccgt tattcgtgga agagagccgc acgccgtctt
    59701 ctaatggttc aatggcatac ctactagcac ttgtgctttc tccgaaaaca acccctttcc
    59761 actcttcatt tgcttcttca gattgctttt ttgtcttttc attttctgat tctttcatca
    59821 taggatcatt tccttcttcc gtatccatat cttcactagt tcttggtatt tcctccattg
    59881 ttgacatccc ttcaatgttc acgtgtgcat tttcttcgtt cacagactgt tgttcgttag
    59941 cagcaacttc aacgacagaa attaaaaccg gggtactgag cataaggaga ttcatcatta
    60001 gcgcactgta ttttatacgt ttttttaaca agtgtattcc tcccgtaaca aattagaaag
    60061 cgtttactta aagtattacc taatttattt ttactgtcaa taaaaaacaa aattataata
    60121 agtgtatttt ataaaaagaa aaaatataac ttaagttgtt gataataaag agatttatta
    60181 acgtaaaaag aataagtttt tttaaaataa cgtataaaaa agagcataaa acaaagtcgt
    60241 ttgttttatg ctcttctttt attattttgt gctttttatt ttatcaaatc actttgtttt
    60301 tttataaaat ttctgcgcct agtgtggact caaaatgtct caatgcccat tcatgtccaa
    60361 cgggatcgaa acttgccacg gaatctttga aaatatggag tttgtatcct agattatacg
    60421 catcgactgc tgtatgcaac acacagatat ctgtacatac gccggtcaaa taaatatctg
    60481 tgatctggcg ttctcgcaaa cggatgtcta gatctgttcc actaaaagcg gaataatgcc
    60541 gtttgtctat ccaataaaca ttttcctctt gctcatagtc ttggtataaa ctttttaaag
    60601 agccgtacaa ttcccgtcca cccgttccta tcacattatg cggaggaaat aagcggttct
    60661 ccggatgaaa ggaatctttt ggatcatgcg catcaatggc aaaaacgaca aaatcctttt
    60721 gatcaataaa cttctttgta tgagcagtca gctttttttc aattacttgt cctgctgtcc
    60781 cagtagtcag ctttccatcc tctgcaacaa aatcatatgt gtagtcaatc gagatcaatg
    60841 cgttcatctt agtcctcctt atacgagatg tttgacaaat tcgatcacca tttctgctga
    60901 tcgtttgcct gcgtcttcga taaattcgtc aaagctttgt gtcgccgagt gatctgctgt
    60961 gtcgctcatt gcacgtacga tcaaaaatgg gatattgaac tgacgagctg tttgtccaac
    61021 agcggctcct tccatttcgc aagctaatgc ttcagggaaa ttcgttaaga tttctttgat
    61081 tttatctggc gagtcgacaa atgtatcacc tgtaacgatc aatccttctt ttgcgttcaa
    61141 attcgttgct tttgctgctt taaccatttc actgcgcaaa tatgtgcttg cttcataata
    61201 tagaggcatt cctggtaatt gtcctgggtt gtagccaaat cctgttgcat ctgcatcaaa
    61261 ataagctact ttgtctgata taacgatgtc acctacttgt aagccttcac cgattccgcc
    61321 agctgaacct gtattgatca ccatgttcac gccgtattgt tggatcaaca gacttgtggt
    61381 aatagatgct aagacttttc ctataccgga acgtacgacg atcacttcgt ggttacctaa
    61441 tgaacctgaa ataaataaag cgcctgcgcg ttcccatgat aatggttcgc ttaggttctc
    61501 tctcaaaatt tttacttctt cttccattgc gccgataata ccgattttca tctttttaat
    61561 tccttctttc tatataaatg cgattgctaa aaaaaccaca cataacatta ggataacaat
    61621 aataagagat ttcatcaaaa aagagttcca tttggtcgtc ttttcccgtt cgctgatcct
    61681 tgttttcgtg attggtttat tctttttgct ttctttacga taaaagctgg caatcttttt
    61741 ttcttcttgc tgataagctg tttctgcttt tcgctgtttt tttaatgact cgcttgcttg
    61801 tgcttgttgt cgcttgcgaa gttcgcttcg cgtaataagc ggtcctttgg ccataagccg
    61861 atccctctac tttcctttgg tcaatagttc ccagtattga atcgcataaa tcgtctttgc
    61921 atcacaaatc aactgatctt tcatcgcttg ttgcgcctct tcaagagtta gatgatacaa
    61981 ctccagtact tcgtcttcat cttgtgctaa aggattctcg accttctcta ccccttgtgc
    62041 atgataaata tgaaggactt catttgcaaa acctggtgaa agatacatcg aagtaagatg
    62101 gctcagcgac ttcgcacgat agccagtttc ttcttctaat tctctagctg ctgtcatttc
    62161 gggattttgt ccttctcctg gatcgatttt tccagctgga atctccaaaa tcactttttc
    62221 taaaggtttt cgaaattgtt tgacaagaag cagacgatct tgttcgtcaa aagcaatgat
    62281 cccgacaccg ccaggatgaa ataccagttc tctcttcgaa gttcctccat ctggcaaacg
    62341 aacttcgtct acagcaacat caataatttt tccgctatag atttctttgc gactgattgt
    62401 tttttcttca aattgctcat tgttcagcat atcttctcct gctttctttg taatcataac
    62461 tgcttttttt tcatttttca atttttctca aaaactcctt attagtttac catagataaa
    62521 ccttagattt tctctaaata tagaaaatcc ttctttagtc cgatactctt tctagtagtc
    62581 cgtatgctaa aataagtatg taatcgaata acgaaaagaa ttcaatactc aacgataaat
    62641 gacatggagg gtttattatg ataaaacgaa attggccgtg gcttctagca ttggtcttgc
    62701 tatttctctt tgtccgaaac aatagttttt cttttgttct aggactttta ttgataggtg
    62761 tagttttagt tttgtgggga ctctttggtt cgcgcaggaa aaagggaaaa caagaagaaa
    62821 ttcctgcact gactgacgaa cttgaaactc actatgaaaa aagcggtatg acagcgaatg
    62881 aaatttcatt ttttcgacaa acaatgaatc aaacaaaaaa tgagatcaat caattgcaaa
    62941 tgaatatgca gcagacagcc aaacttaaag caatcgatct ccgccatgat ccagtcaaag
    63001 cagcgaaagc tttattcaaa gaattggtga aagaaccaaa ccgactgcat gaagcaagtc
    63061 agtttcttta tacgcatctg ccgaatctag ttgatttgac aaataagtat aatgagatca
    63121 atgaccatga gatcaaaaac aaacagacct atgaaaaact agaagaaagc gcgcagatca
    63181 tcgaccagct gtcagcttta atcgcacaag attatcaaaa attcgttgct gaggatctag
    63241 atgatatcga cgtagagata tctgttgcga aacagagctt aaagcgtgat aataaatatg
    63301 aaccagaaca aaaggattaa ctcttttgtt cataaaagaa gactcggaac attcagatga
    63361 tgtctggctg tttcgagtac tttttctaaa gtagagacat tcatgtaaga atcgagaaca
    63421 gattcaacaa ggaggaattt tttatggatc ataaaccgac tgaaacaaaa gatgttacac
    63481 cagttaacga tacacttgaa gatttattga acaacccgtt ttcaactcca acagatacgc
    63541 tgaccacttc acaacaagcg gagattgatc agctccaaga gcaacagaca gctgctcgtt
    63601 taattgacaa actaccggcg gaacgccaag aacaagctaa acagctagca gcaaaaatcg
    63661 atgctaatga tgcacagtct gtcatcagct acggatcggc tgcccaagca aaattaagtg
    63721 aattctcaca atcgatgttg aatcatgtgc aagcacaaga tattggtcct gtaggagatt
    63781 ccttaactga actgatgtat cgtctccaag aagccaatcc tgacgaactg cgtgccggag
    63841 aagggaacat cttccagcgt gtcttcggga aggtcaaaca atcgatctat gaagtgacag
    63901 caaaatatca aaagattggt gcacaaattg acaagatttc agtgaaatta gataaagaaa
    63961 aagacggtct gctaaaagat aatctgatgt tagaacagct ttaccagaaa aacaaagact
    64021 actttgatgc actgaatatt tatatcgctg ctggagaatt gaaaatggaa gaacttcaaa
    64081 caacgatcat tccagaagcg atgaaaagag cagaagaaac tggcgatcag atggatgttc
    64141 agattgccaa tgattacacg caattcctag atcgtctgga taaacgtacg catgatcttc
    64201 gcttagctag acagatcacg atccagcaag caccacaaat ccgtttgatc caaaacacaa
    64261 atcaggcctt ggctgaaaag atccaagcat ctatcgctac agccattccg ctgtggaaaa
    64321 accaagtcgt gatcgcattg accttgcttc gtcaaaaaga tgcagtaact gctcaacgcc
    64381 aagtctctga aacaacaaac gacttattga agaaaaattc agaaatgctg aaaatctcag
    64441 ccatcgaaac agcgaaagaa aatgaacgtg gaatcgtgga tatcgagacc cttcaaacca
    64501 ctcaaaatga tttgatcgaa acaatccaag agacattgcg tatccaaaaa gaaggaaaag
    64561 aaaaacgtcg tcatgcagaa gtagagcttg gacacatgga agaagatctg aaacaaaaac
    64621 tgttggattt aacccaatag atcacctttc gcttgttact aaaacaaacg cccaacaaca
    64681 gtttattaca actgttgatg ggcgtttttc ttatctttct tctaacttct ccattggagt
    64741 ctatttctca ttcatcttgc tgtgtccata gccatagcca aaataaatga tcagtccaat
    64801 aaccattacg ataccgaaca cgatccatgt cacagtttgc agacgaagca tcaatacaat
    64861 acaagtcaaa atggagacga ttggcaatag cggaacgaat ggcactttga attctccagc
    64921 ttttggtttg ccaaacattt ttctcaactt cagtaagcct agactaacaa gcatcaaata
    64981 ggcgagcgcc atgatattcg ttagttccgc taatacattc aatgggaaaa atccggcaaa
    65041 gaatacagct gccacaccag cggcataagt cgcttttttc ggtgtacgat gcttttgatc
    65101 gatttctgtc ataaacttag gaagtaagcc atccttgctg acagcaaaca gtaaacgagc
    65161 aagtgaatac atcatcgaga tcgttaccgt cagtagcgtt aaaattgccc ctacagcgat
    65221 caccgcgccc actgttccat gtcctacata cctcattgca aaagccactg ggtcattgac
    65281 tcctagttca gtatacggaa cgattcctgt caagatcagc gtcacgatga tgtaaaggac
    65341 agtagcaatc agtatcgaac caatgattcc tcttggcaca tctttttgcg ggtttttgac
    65401 ttcctcggct gccattgcaa cggcatcaaa tcccaagaaa gcaaaaaaca caagagctgc
    65461 accatctagc acaccggaaa aaccaaaagg catgaatggc tgccagttat caggtttaac
    65521 gaaaaatatt cctacaatga taaacaacgc gatgatacca aatttgacat ataccatggc
    65581 attattcaaa cgtaatgctt tcttggcttc aagcgacacg atgtaagtga cgaatatcac
    65641 tacgagcacc gcaatcaagt caatgtatgt accattttcc ggattgtacc cgccagttaa
    65701 tgcttgtgga agttcggccc ctaaactttt caaaaaacct tgcatatagc cagaccatcc
    65761 ggaagcaaca gaggaaaccg ctagtaaaaa ttccccgatc aacaaccacc ctgtcagcca
    65821 ggcagcaaat tcaccaaata caacatacag ataggcatat ggcccaccaa tcactggcac
    65881 tcgcgaagca aattctgcga aacttagtcc agacaaaatg acaacgattg cagctaagac
    65941 aaatgaaagt gacagtgctg gaccagcatt ttgattggcc gcaacccctg tcaccacaaa
    66001 tattcccgta ccgatgatcg caccaattcc aagcatgatc aaatcagacg tttttagttc
    66061 ttttttcatc tcactcgtat gattgagatt gatctctttc ttacgaaaca aatccattga
    66121 agttcctccc cattttaggt tggaaaacag cgattaaact gttttcatat accctaaaag
    66181 gataccacct aaaatgacta aaaggcaacc aacaataaca taaatgagct cttttttcgt
    66241 ttttctttcg ccaaggatga aaatcccacc taaagtagag ataatgatcc ccatttgtga
    66301 aagtgagaag ccaacagcta aaccaagtga tttgactgtt agaagcatgc agatgtttcc
    66361 taagccccat aataatccac agatcatgtt tttccacaca aactgatcga ctttaacttt
    66421 acggaaagca aagaagcttg cgcctaagat cattccgata ctttgaggta agataattga
    66481 catcgcatcc aaattcgccc agttgacgat gatggtatat acaccataac caatcgtaga
    66541 gaagatcaat gctctaaaac ccttaccaaa atcaagcatt ttattatctg tatctatttt
    66601 tccttcgtca tcttgtcggg cagtcaaata cgcaccgctt acaagaagag ctaaagcaat
    66661 aataccgtat acataatctt tcgtttgtgt ccattcatgg aagaaaacgg ctcccgcaat
    66721 cgtattcaaa attaattgaa aaccagtaga caatggtagc cctacagaaa cacccatgta
    66781 cttcattcca tggaactgtc cattttgtcc aacactccaa gctaagccgg ataaaaatcc
    66841 gatcaagaaa atccaagggg tgattacagg actaacaacg aaaaagacaa ctaaagaaaa
    66901 cagaaatgca ccgatcgtca ttcctagtgt ttgttgattg gcatcgccac caattttacc
    66961 acttactaaa ccaatactac cccatgccaa catagggact aatgctatta aaatttccat
    67021 aaccaatctc cttttatttc acatgataag aaacttatca gcgaaaacgt taacaacaca
    67081 agcacttttt ttcgtttcta acgattttct aacgtttttc attataaaaa tttaagattg
    67141 ggaaaaataa agtcattgtt gtcccttttc cttcagttga ttcagccgtc aaatggatac
    67201 ctaatttttc ggccagattt tttgctaaat aaagtcctaa tcctgttgaa tgtgttttgc
    67261 taagtcgacc atttctccca gtaaatccct tatcaaagat ccgtttcaag tcttccgctg
    67321 ggataccgat ccctgaatct ttaactgaaa ggctgactcc ttgcgcttcc ttttctatgc
    67381 tcacaatgat gtttccgtga tccggcgtat atttgatggc attactaagc aattggttga
    67441 agataaaagc gatccattta gcatcggtca aaacagtatg atcctcacca acgatctcgt
    67501 agcgaatatt tttttggata aaataatttg cctgactgcg tatcacaggc tgaatgattc
    67561 cttttagtcc atattcttgg atgaggtagt cccgcgagaa actgtcgagt cttgcataat
    67621 acaaaacttg ttctacgtat tcatcgattt ttgataattc attttctagt aatgtatact
    67681 tttgatcgtc aatatcgaac tcgatcgaac gaactagcaa tttagaagcg gaaagtggca
    67741 ctttgatttc atggacccat gagtcaatat aatctttttg gtcttgttga ttactgattg
    67801 ctgattgcat tacttcttgg tgttcacgga tcagctgatt gatatattct tctaccagtt
    67861 tttcttcttc tgtcctccca ccactcaaat aattttgcaa aggggaagtt ttttgtatgt
    67921 cggctaattt tccccaccat cttctcttgc tcaagtaacc acccagcaga taaaaaatca
    67981 gaaagacgcc ctcaatcaaa gctaaataag caattgtgct caaatcaact ttgatgtttg
    68041 gcgccagcca catcacaaag atcgtcaatg caataaaaaa cagccatccc aagatcaatg
    68101 tccactgatc tttcaaatat ttaaaaaaat tcatcttaac cgctcatcct ttcagggaac
    68161 gatatatccc tgtcctactt ttgtttcgat atatccttgg atacctgcct gttcgatttt
    68221 tcggcgtaac cgattgatgt tgactgtcaa tgtattgtca tctacaaatc gttcgtcatc
    68281 ccacagtgct cgcagcaatt tttcccgact taagatcttt ccattgtgct tcatcaaaat
    68341 aaataataga cgatattcat ttttgctcaa atcaatgatc tctccgttga tttccatact
    68401 tccgttgtca acattcaacg taatgccatt gtggctcatc atttcactag ataattctgt
    68461 gtagttgtaa gaacggcgaa gtaatgcatt gatttttgca atcagtacat cgatttggaa
    68521 atgttttgtc acaaaatcat ctgcccccat gttcatagcc atgatcatat ccatattcgt
    68581 attcctgctg gagataaaaa tgatcggtac tttcgatact tcacgtattt tttgacacca
    68641 ataatagcca tccaaaacgg gaagattaat atctagtaat acaagctgtg gttcttctct
    68701 ttcaaagtct gagaacactt gattgaaatc ggtcgttcca aaggtttcaa attgccattt
    68761 ctcaagttcc tccatgatca attgtcgaat gatctcttcg tcttcgacta ccatgatttt
    68821 tgccataaaa aatccctcca tctttcttct tgctactaca atatcaaaga agcccttgtg
    68881 aaacaagttg gcttacctgg aaaatgtcat tttagcaaac gttaaaaaaa actggaaata
    68941 tgcgatttaa tcgcgtttgt ctcttccaag cagcttaaat ttattatgtt attcttaata
    69001 attggtctat tatctgttat ttttctttcg ttgtttttgt cttttaaatt ttcgataaca
    69061 ccaataaccg aaaagcgtta gcactagcaa tatacctaga aggagtataa gtaatcgata
    69121 aagatggtat ttttttgtct gttctatctt tgaagagact tcttctgtaa agggaactcg
    69181 tcttcctgtc actagtaatc ggtgagtgtt cacggtgtaa ggtgtacaag tgataagtgt
    69241 gactagatcc tgcttttctc taattgctaa tgtatttgtt tttgttggaa ggacaacaat
    69301 tttctcaacg acttcataag cgagcatccg accatacact tcaagataga atcggtcatc
    69361 ttgctccatt tcttcaagat ccgtaaagag ttttttctca gcaataccgc tatgggcggt
    69421 aatcacggaa tgtgtactct ctcctccagt tggaaaagag gtgccttgca ggactgtcgc
    69481 tcctctatct aacaaaagat cattcgtttc atcaaataaa ggcaagctaa cattgatttt
    69541 cggaatatag atggctccga tcatatgttg ttcgtaatat tcttttcctg gattttggac
    69601 atttctaacc gcttgctcaa aaggatcttt gacttgtccc attcctggga ttactgatgt
    69661 atgagcaagc gtctgatttt tcttttcatg cactgctaat tgttgctcat gtttttcttc
    69721 tttatcgcgt tcaagctgct tttgataatt ctcgatcctt ctttgatcca aataattgct
    69781 gagagcatct gctaaaaatg gatatgtaaa aactgcagct ccggcaagaa acatcactgc
    69841 cataaataat tgtaataaaa gactgatttg ggtttgaggt ctattaccta ttttcttttt
    69901 cattttcttc accttcttat ttaaaaaaac tgcagcaacc tttataaaac cgattgctgc
    69961 agcttatttt tgttgcttat acttcagact tcattttaga tttacggtac cagctgtacg
    70021 ctccaatcat caaacttatt ccgattagta agaatgccaa gagcccgttc ccaccagtag
    70081 caggaagtga cccgcgtttc atattcggta ctctttctgg ccctggattt tctactccta
    70141 cgatctgaat ttcttcatta tagcttccat aagagatgat aaattcagta aaggctgcct
    70201 cacctgttgg aagtacataa ccttctggcg ccatggtctc tttcatttga taggttccat
    70261 aatctaaccc ttgaacctca aagtatccat ttccatctgc gacaaattct gttgcttgtc
    70321 cgcttgttgc ccactcaatt ctatctgctc ctgattcata aacagctaaa ggcgactccc
    70381 ctttataaaa tattgcgtat tcagaacggt cttcattcca caattcgaat cttgcatctt
    70441 taagcaattc actgcttgat gcatcatatt tttcaaactt tcttccacct gttgtgactt
    70501 tctctggcgg ctctactcct tcttcataat caaattcatc atttcgtccg atttcaataa
    70561 ccgctgtgtt gttatggaaa tcatccgctt ctagttctgt ggaaaccttc aaattatacg
    70621 tgatcgttaa atctcctcca cgtgcatctg ctaatctacc taaagtatct actttggcta
    70681 ctccattttc ttctgtcaaa atcgtcacga caaacccgtt gcttactact tctactatat
    70741 aatcttgtcc ttttgttaaa atcgtctcgc cggctcgcac ttctatttcc tgatcataat
    70801 aagttagacc aactgtaggc gtatctgtga ttttgtaatt tttgataaca gcgcttccgt
    70861 tttcaaggac agaatcgatg aaataaggaa taggtgctgt gatcgtgtaa gaagccgttt
    70921 ttcctctttc tagatcaata taagaaatcg tttcttgttc tccagcttca ttaataatcg
    70981 ttacttgtct aaggtcgctt tcctctacat tcatctgttt atctgcttct ctgatttcgt
    71041 ttttcggata caaatgcaca tctgtattgt atgtgtcttt ccatgtagaa ccatcccaca
    71101 cgccatccac catatcaggc atcatcactg gcatcataac aaccattgga gacgcgattc
    71161 tggaaatatg agctggcgaa taagtttcta agaaaagata gactttatct ctagaagaag
    71221 gtgcttcttc cgtcacttgg acggtagaga ataccgcttc tccagcttca ttcgttgttt
    71281 gtttgtcaat acttgtcagt cgatatttta aaaaccaact ttctgtgtgc cgtttttgaa
    71341 tccattcaat cgcttcggca gaattaagac cgtcttctcg ttccggtgtt aaaggattat
    71401 ctcgaatcaa atcgtaatat acttccgtta cgtcaaacaa atcaaaatcg actcctggaa
    71461 tattttcttc accaaaatcc gtagaaacca atccgctatt cggtcgttct tccggaacag
    71521 atgagaaacc ttttttgtgt aatgtaatcg tcacttcact tggtttttgt gcgacttctt
    71581 cggctttgac tagttttccg ttcccgaaaa tccctattcc cgcagtaacg agtaacagta
    71641 cactcattcc cgtgacaatc atttttttat tcattttttt ctccccgttc tttttttatt
    71701 aataaaacag cacctaacaa taaaagaatt cctagtaaag aaatcaacgt tcttgcttca
    71761 ttcgtttgcg ggaatacgga ccattttcct gattgacctg gattgcttgg accactcggc
    71821 tctttcggtt tgtccgttgt ttcttttacg gtctcgttat aaacacgtgg tgttgcggat
    71881 tcataggcag agactggaac tttcccggat tctaattcag ccatctcctg tccgttaact
    71941 actacatatt gtggttggcc ttttgcatcc acccaaaatt cagggatgat gacctcgatt
    72001 ctcttacttg cttcatccat ctcgtaacct tccacacctt ttaattcttc aaaataatag
    72061 gtgccagaag gcaagaaacg ttgtcctgtc gtaacaaggc cctctttatc cgaaatgaat
    72121 ttgcttacat ttttgtcatt caaaggatca ttgtctgctg gtttgatcca ttgatttttc
    72181 aagtcattag caggagccat atctaaataa tatttccccc ttctatcatc tgatatagag
    72241 caaaaacagc accttctaat ggttttcctt tttcagttgt tcctctttga cgtccatact
    72301 tgaagaagta tggatctctt agataaccga catttttagg atagatatga atctcttgca
    72361 gttcctcggt tgattctgtc gggtgataaa ttggcaaaat agcagcaatt gggatagctg
    72421 tctgatcgat atcaacatcc aatccaactt ctggatcaat cgattcttcg aaaatcaaat
    72481 aaactgcatc ccgatcttgg tttttcttag gtgctttgat acgtgcaatc ccgtctccta
    72541 atccgccaac cgtatctttc ccagttgtta ccgaagtccc tatttggaca agcctttctt
    72601 ctgtgattag ctgacggata ttgtttctgt tcgtttcagc gatttgctgg acgaattctt
    72661 taggagtcat gttttcagca gctttttttt catgataata atcggtcatg tcgtaaatgg
    72721 caaatgtcgc tccatttagt ggcaccgtct gtgaaatgat atctgctgtt tcccctgctt
    72781 cctcagagat agccaagcca tcattttcat ggtattcaaa ttgatcgtta taatcgatat
    72841 ctcgaatcat ccgtttatgc aacacgaatt ccacgacatc ttcccctgat tcttctgccg
    72901 acatcgcatg tggaagaagg actgctgcaa gcggtagtaa aacaagtaat tgaagcatca
    72961 aacacaacag ctttttcatt accttgctcc ctccttttta gattgtctga caaacaaacc
    73021 ataggctgct cctgcaagcg ccatgaagaa tgcagcaagc aggatataga ataatcgtcc
    73081 ggatcctcct gtagcaggca acggattttc aggatcgttc ccgacactaa gctgtaatct
    73141 gattcgattt gtctccaaaa gttcatattc taactcttgc tgtagatcag gcgtctctgc
    73201 ttcttcgttt ggataatacg aaatctcaac ttttagtgta cccgcttctt ttcctggaac
    73261 tacccgatca ttttctatgt caggttcttc tcgataacta atttctaaaa taaagtaacc
    73321 tggaagtttt ctatagctgt caggtgactt cacttccttg atccgataga ccccttccaa
    73381 caagtctgaa gcattgaata gggaagaatc gtttggatct ggtgccaagc ctccctcgat
    73441 gatttcatac tctcctgcac tattttgttt ctcaattgaa aattctgcgc cttcaagacg
    73501 tcggctattc atactgtcaa ttttcaaaag ttccaaatcg attggcgcta gttcatcttc
    73561 taaggttact tgtagtacac catcgatgat ttcatagcct tccggcaagg gagcagtttc
    73621 gtcttcgatg accgtatctt caatgataaa cttaccttct tcattcagtg caaactggaa
    73681 cacttgatca gatagccgat acccatttgg tgcgacagat tccgagacct catattcacc
    73741 aatagacaga tgcagaggtt ggtcgtaatt taaatcgaca tacttttcta ctcctacggc
    73801 acgagaatag aagtatccga tcccaggcaa acgtttcgat tcttctggtt ctaacggatt
    73861 accagtgtat gctcgataca gcgggaagga agaatccccc actttcctga tatcgaaacc
    73921 tgcaccatct aatgtatggc cttcatggtc taattttcta actcggatct cccgataatc
    73981 aaacgtattg taagcagtga atgctaccca taaacgatcc tcttcatctg ttgtatacgt
    74041 gagatattgc caattttctt cacctgtttg cttgagttgg atagtcccta tagcattatc
    74101 gtaaagtcgc aagatccatg tgtcattttc atcaggttct ttgaaacctt ctgggttctg
    74161 gctctcaatg attttgtatt ctgcatagtt ggtagtttct tcactatcct tataaacaaa
    74221 tgaatctggc tctccgattg gatgaataac tttctcacca tccacgatta catatttccc
    74281 gtcttcatct actgaataga acgtgagtct ccctttctct tcctctactt cgttcacacc
    74341 agaaagccct ttcgctactg gatatccgat ttccagtccg ttaccatctg tttcataaag
    74401 ttcaaactct gcgccattga ttggcatatt actgccttca attagtttat tgatattcat
    74461 gtggattggc ttgaattcat ttcgcatttc cagtttgaca tacaactcat catactctgt
    74521 gccttctatg ttaggctctt gtacaacaga aagcttgtga tattctcctt cataatagga
    74581 attcggatct ttaccttccg gtccgccgac tctcgaacca gatgtatatt catctacaag
    74641 ctcgtagtga cctaacatct catcttcgtt ggctgcatat tttttgattt ggaattgata
    74701 cgtctcatct actaactgat aacgtggtgg tccagcgatc tctctgatcc aaaatatgtc
    74761 gctgactgct ccagtttcat ctcctaaaat cggcatcttc gtttcaaaga tcgctattcc
    74821 gtccgtggta gttttacttg tttcgattgg ttcggcttcc ccactctctg gattttggtc
    74881 atataatgca aattcgactc cagccaacgg ctcgccattt tgacccttct tgctgacttg
    74941 gaaattacgg cctttatgtt cgtaacgaat ggaagaagat gggaaataca tccgtccagt
    75001 agtgatatca ttctcataat cctccaggtt ctgaatatag gccatattgt tcactgtgca
    75061 aaaatttccg tcttgagctc ccgcatcaag ttttacttgg tacttgatcc tgaccatttc
    75121 cccttcacct aaagaaatcg gagaaaattt ataagcttgg ttttcccgtc cgacatacgt
    75181 tgtcggagtc gccactactt ctggtggggc ttgtccatga cgttcttcat cccatatttc
    75241 tggctcttgg tacttcatgc cgttttctcc tggatctaga tggtaaaact gaatatctgc
    75301 cgatctgcca gctccaaatg gtgagacatt aaaaccagtt tcatcataaa gtgtggcttg
    75361 ctggatcgtt ctcttgaagg tagaagagat atcctccaag gctgtaacaa tgtcattctt
    75421 gttgttcgca ttgtaatatc gcggtgttac gccatcttct tctaaatcag caatattttt
    75481 caatacattt cgtccaatag catctagtcg ttgtctcccg ctaacgtttc catcgattcc
    75541 taaaccaatg gagaagatac ttggcgggtt ctcttgatac ttgtttttca gccaatgatg
    75601 ataagcaact gtgttgatcg cagatgactt ttcttgcgaa gtaggactgc cattcgtatt
    75661 gttattagaa gaaccatcac caacccagtg agtcgcttta ttatctcctt cttttacctc
    75721 tccataacga tagtgtacat ttacttcatc ttctggacgg ttaaagtcag atgcataggt
    75781 aactggatga gtaaaccctg cattagaagt attcccagaa aactcctcaa aatttctgaa
    75841 caaaacgtca ttatcttcag caatcttatc ttccatcaca gtccagttgc tccaagctcc
    75901 attagtgctc gtacgataac ttgactgaat cggtgcataa ctgaaggtcg gtgtcccatc
    75961 tcccacaacg attaggattt tttctggatt tctattttct ccgccattgt ctttatacaa
    76021 tgtttcatag ccatttttaa gccctagtgt aagcggagtt cctccgattg gtgtacgatt
    76081 taatgctgta ttctcacttc ccgtcaaacg attgatatca tttgtcaatg gaaagatgtc
    76141 cgaactgatt tgctcatggt tattgatagc tgtactatta tggtaaaaat tcaccatacc
    76201 gattcgaata tccagactcg ggtcagagag cagatcttta ctcatttcgt ttactgcctc
    76261 aatcaacgca gcatttttag tttgactatt ggtcccagcg gttaattcac tcatactcgc
    76321 tgacttatct agaacaaaaa cgatatcgat tggactgatt tcctttttct cgcccccgat
    76381 gacatctaga tagacattgt aaagggttgt tgcatcttca ggatgtagat cagatgctgt
    76441 gctgcttggc agaacaggtt ctacccattt tttgatgtac gccccgttat aatccaagta
    76501 actgttttca aaattccgtt catttcccca aagctgaacg gtttgagctg gaacgtttct
    76561 atcttcttcg cctgcagttg atccattatt agtagcatag tcgtaatttc gccagttcgc
    76621 tcccccgttt gtataatcac tatcatcgat caagttctct ccgtcatatg gcgagccttt
    76681 gtctccttga tagcgttcat tgctttgtgt ccaatttcct aacacttttg tatagtcatt
    76741 cgttgtaaac ttcgggtagc gatgctgttc gttttcaact tctccgctag gatagatata
    76801 ttcatagggg tcttgcgtag ctgttggccc aagacgctcc aaaataccgt tgaataactg
    76861 gcgttgaatg cgctggagtg cttgaccgct gggtacgatt ggttcgtcca gcttttccat
    76921 ctcattttct tcgctacgtt gaatttcagc ggaatcttct gtatcagttt cattttcttg
    76981 taattcttgg ttatctattc tttcatcaac caccacttga agaggtagtt acccttcgtt
    77041 cacatcgggg atcttttctg tttcaaaaat caatgtgccg gtttctgctt cttttgaata
    77101 aacttttccg acataccatt cttgaccatc gatcgtctcg acttttaggt cttctccatc
    77161 ttcatcatag gaggatagac ctgttccacg aacgtttttt acggtaccaa tcccggcggc
    77221 tgccgcatcg attgctaaac gtattctacc ttcattggca ctttcctttt tttcaaaagc
    77281 cagatgccat tcaagggttt cttctttttc aatatacttc ccttcaattt ttgcatagtc
    77341 ctcatctaag aatacctcat cctcctttgt ttctgttgac tcagcagcta catccagggt
    77401 cgtcatatga tagactgact ggaaatatgg tccaaatagc aaactgacag ttactaactg
    77461 caaaagcttc aattttaacc ctttcacatc cttatactcc tttcaaaaat atttgtcttc
    77521 tttcacaaca atcaacaaaa caatgcccat ctaattataa tttaatttaa ttttaatttt
    77581 aaatcaaatg atatcctttt tagttaaaaa acaccaatta tacaacattt attattaaaa
    77641 ttaaattata aaattttata acgttctcat ttaacaaaac ttaagttatt aagacaaatg
    77701 aataaacaac tacgctttcc tcgaaacaaa aaaataaagc acaaatgcgc atttacgcac
    77761 tcatgcttta ttcgtacaat taattcagat aacggcagcg cataggatgc caataacact
    77821 tcctaaaata gctcctccta aaatgtcagt aggataatgt aaaagtaaaa aaatcctcga
    77881 ataagcgatc aaacaagcaa ataaaaaggc taatattcct gcaactggac ttaattcgaa
    77941 caacgcagct actgataaaa aggctagcgc tgtatgtcct gaaggaaaag aagaagtctt
    78001 cggtttactt gtgtaaagga caagccgacg atttttttca taaggtcttt tccgtcttgt
    78061 cgtttttttg ataaaaagca aaccaacaaa aaaatagatc aaactgccga taagaatggc
    78121 tagaccatat tctctagtat caggtatcaa gactaaaaca gcagcaagga gcaaccaaat
    78181 aaaaccacca ttagagatat tactgataaa tttcaaaaaa ttgatttttc gactatccgt
    78241 tttccgttgc ttggcgaact tgttgataat actatcatcg attttagcaa tcaaacgcaa
    78301 catgttattc ctccttttta agaacctttt cttgcgtacg atggataaaa agcaggactt
    78361 gaaaataaaa caagaaactg aaacctaata aagcaaaata gattggtcct gcaaaccaga
    78421 atgcgacaag aaggatcaac gtgcctgcca aatagaaaag cgcgcttttg aaatcattaa
    78481 aaaacaagaa aaatgcagta atccaagaag cttctttttg ttccagttga agcaagattt
    78541 tgtaactaaa gagaagcgcg cttaatagaa gcaaaaacaa cgtagtatac atcaatgtat
    78601 agccaattcc cccaccccaa tagcggaaaa tctgataatc gatcaataga agaagaaaat
    78661 aaacacttgc taaactatct tgctttccat aaagagagaa gttctcacga aactttttcc
    78721 agaatagtga accgagcttt ttctcttcat tttttttgta atgataaatc atatacagaa
    78781 ctgttcgact tgcagttcct aatgtgaaaa caggcaagac gcacaggaac catagtagct
    78841 gtaaatggat aagacgtgga atccattcaa tgatttctaa gaaataatca ttggcttttt
    78901 taccaatcga tcgattcatc atccttttga acctcctgtc aaatccatcc cttcaatgaa
    78961 ataacgttgt gcaaaaaaga acagcaaaat cgtcgggatc aagacaagtg ttgctcctgc
    79021 catcagataa ttccattgtg tcgttgcttg gttctgaaaa acttgcaagc caatctgtaa
    79081 cgtgtatttt tcttgatctt ggatatataa cagaggacct aagaaatcat tccaagctgc
    79141 gttgaaggaa ttgatcgcaa tggtaatcaa ggcaggtttc gtcaatggaa gcatcaaatg
    79201 actccaaata tacaaatgat tcgctccgtc gatttcagca gcttcgatca attcattatt
    79261 gatcgataag taaaattgac gcatcagaaa tatattgaac gcattgccga agaacgatgg
    79321 aacgatcagg ggcaaataag tacctaccca gccgatcttg gagaataata catattgagg
    79381 gatcatcgtt acaaaccccg ggatcatcat cgtagaaaga accaaagcaa acatcagctt
    79441 tttcccagga aaatcaagct tcgcaaatcc ataagcaata aaagaatttg aaaggacatt
    79501 accgatcact actagcacag tgatgaataa tgtatttctt gcatagcgcc aaaaaggaaa
    79561 ggcggcaatc gtatccagat agttttccca tacgattttt tctgggaaaa aggtcggagg
    79621 ataacgaacg atttcttcca ttggtttcaa tgaagtaaac accatccaaa gcaatggaat
    79681 gatcaaaatg attcctatta ctgtcatgag gacataactt agtatttttt ttgtttgccg
    79741 attcacactg gtctttttga aataatccat catttgccgt cacctccaga ataatagacc
    79801 cacttaggtg caagcttcaa attgacaaac gtcagaacca acacgatcag aaacaggatc
    79861 attgacatag ccatcgcata acccatatca aaagctacga acgccttgtt ccacatatgc
    79921 agattataaa aaagcaaaga atttgcaggt ccgcctgttc catttttcgt catgacataa
    79981 gcttcttgaa aaatttggaa agaaccgatc gtagaggtga tcacatcgta aaaaataata
    80041 ggagtgatta atggcaaagt aatacttttg aactttcccc aaacgcctgc tccatcgatt
    80101 tctgctgatt catataaaga tctaggaaca ttttgtaatg tagctaagta aagtagcatt
    80161 gctcctccag aactccatat tttcatcaaa atcaacgcag gtttcgtcca ttgtggatca
    80221 aacagccaag ctggtccagg gatatggaac cagcccagaa atgtgttgat caatcctgca
    80281 gatggagaaa gcagctgcat ccataagatg tagactgcta ctcctgataa gactgccggt
    80341 aaatagaaag ctgtacggaa tacactgatt cctttgattt tttgattgag tactgtggct
    80401 aaaaacacac tgaaaatcgt cgtcagcggt acattgaaga tgacgaaata aacggtgttg
    80461 tataacgatt tccaaaataa atcatcgtga acgaacattc ttttgaaatt tgctagacca
    80521 atgaaattca tcttggatgt caaattataa tcggtgaaac taccaataac tgaaaaaagc
    80581 ataggcccta gcataaatac caagaacccg ataataaaag gcgagataaa taaataggcc
    80641 catcttgctt cttttttctt tcggatagat aaacgcttca aattttcttg cctcctctgt
    80701 acctagacag tcaaaaatgg attattgatt ttgcttgact aagttttcta ctgctttttg
    80761 tgcatctgcc aatccttctt ttggtgattt tgttcctaaa agaatctggt caatctgttc
    80821 attcactaat gtcgtgtaat ccggagcatc taaaggaact ggtgtgatca ccgtattttt
    80881 aaagttttcg tccgccattt gatagatcat ttttccttta tccgttaggt tgtcattatt
    80941 cactaaattc tcattggctg tcttgctcgc catgatatca aaactttttt cgccgaattt
    81001 ttcttgtact tctggagaag aaagatattt gatgaattca taagaggcct caggatcttt
    81061 tgctccgtat ggtacttcca agacgaatcc gccaccccac gaccaatggc ctgaaccttc
    81121 ttctttttct gggagctgca tcacgccaaa atcaaaatca tccggtgcat tttccatcaa
    81181 actagagtaa taattgatat tttgggcacg catggctact aatccggaaa taaatggatc
    81241 agatacacca gacccaaatt cggcttctaa tttattgatc gtatttttcc cataataatc
    81301 ttgccagtct tggatccact ccaaggcttc cactttattt ttagtatcaa tcttgacttt
    81361 ttcatctttg tcaaaccaac tagtcccgtt atctgcgttt agcgcccata catcagcccc
    81421 taaattccat aatggataaa aaccgatgcg tgtaaattct tttccttctt ttttatctag
    81481 tttacgtgct gtttcttcta attcatccca agttgtcggt agatcttgtt cactgattcc
    81541 agcttcttta aataactttt tattataaaa aatgacttgt gtatctgtat tgaatgggat
    81601 cgcataagga tcaccttcat attctactgt atcccaaagc tgcggataaa aatccttaga
    81661 agtgtctttt tctacatatt tggagagatt agttgcttgc tgtgcttctg ctctttgggc
    81721 aacggaattt atgtcctgta caataacatc gggtgcattt ccagctgtta ttgcagataa
    81781 agatttagtc cagatgtcac cccatggctg atacttataa tttacatgga tctcgttttg
    81841 tgattgattg aaatcctcaa tgatttcttc gatagcttct tttcgtgcac cggatcccca
    81901 aaaggaccag aaatcaatat tttttcttcc atcacttgtt ttttcagaag aatttgctgc
    81961 acttgaactg gcatcgcttg cattacttga tccgcatcct cctaataaaa acaatgctga
    82021 acttgccagc aaccctgtaa acaataattt tttcatattt tacctccaaa ttttaatgta
    82081 accgatgccg gttttaatat aacgatatca ttttgttctg aaaataacaa tttataaggt
    82141 atgattctaa aaaaattatt aatgatacca atactttata taattcgcga gcgctttctt
    82201 tgaatttttt aatctttcgt agcagaatga gaatgtatta aaaatagatt aggaggaatt
    82261 ttgatgttta gacaccagaa agaattgcag tttgaagcaa aaccagatcg tccgaatcca
    82321 ttaatcgcga aatatctgca ggagctgatc ggcggccaat atggcgagat gagtgtagct
    82381 atgcagtacc tgttccaagg ctggagctgc cgaggagaag aaaaatataa agatatgctg
    82441 atggacattg caacagaaga aatcggccac gtggaaatgt tggcgacaat ggttgctcgt
    82501 ttattagagg gtgcgcctgt tgaagatcaa gaagcagcga tgcaaaaaga tccaacaatc
    82561 ggtgccatta tctctggaat gaatccacag cacgcgatcg tagctggctt aggacctcgt
    82621 cctgctgaca gcgtgggcaa tccatggagc ggtgcctata tcattgcgag tggcaacttg
    82681 ttagcagact ttagagctaa tttaaatgcc gaatcacaag gaagacttca agtagcacgt
    82741 atttacgaaa tgatcgatga tcgtggcgta aaagatatgc tgtctgttct ccttgcaaga
    82801 gatagctatc atcaaaatct atgggaatgt gcagtgaaag aattagaaga aaaagaaggt
    82861 tcaatcttag tcccaagtac tttcccgcgt gacaaagaac gaaaagacat tgcttatgac
    82921 ttctataact tctcagaggg agaccaaagt agtgaaggtt cttgggctag tggcaaagca
    82981 ctggatggcg aaggcgaata tcaatggttg aaagaaccta agatcgaagg cgctgcacca
    83041 aaattagaac cagtaacacc aaaaatgtat gggacacctc cattcaagaa ataaatatct
    83101 acccgtagaa acacccgttt tttgttccac acgctttgtg agcaaaactg actaaagtca
    83161 ttaatcataa ccacccttca aaagggtggt tttctctaga gctataagct caaatcaccg
    83221 gccagcgcct aaagacgctg gctttcatat tttatgttca agccatattg cctttgccag
    83281 ttttgcccac ctcttaaaag gtttatgtac tactccttag cccttaaaag gatcgtctta
    83341 ctctcgtaca ctcagcttat ctaacgcact atcatgtttt tcttgttctt gaatgtactt
    83401 tttgatggtc gcttcatttt gtcctacttt tgtcacatag tatccttcca cccaaaagtg
    83461 tcgataccca aatttatatt ttagatttgc acaatctctt gatgatctcc tgaatattgg
    83521 ctcgatattg attataaatt atttttcttc tatactttgg tgtgaataca atgtggtatt
    83581 tacacatcta ctttgtacgg gctaaactat ttccctttat tgctccaccc gcatagcaag
    83641 tggttttgta tttcaatcgc tcggcgcgct caattaggtc taaagacaat aaatctaaaa
    83701 acccgctgct tcactgacag aaacaacggg ttttcagaaa aaaatgaaat gaaaaagatc
    83761 tcttacggca atctatttta tttttttgat tttttataaa tggaaaatgc ttcaagaagt
    83821 ccaagaaata aagccgtata aaaacaagaa cctatgaaat ctttatttat tagatattca
    83881 acagaaatcc cgataacact agccaacaat atatttatca gaagtgtaaa ataaggatgc
    83941 tttttataga atagaactag tgttgttttc atagactctc ctttcttcat atttccaatt
    84001 aatcacaaat tcacggcatt actagaaaaa ttaaaggggc gcagaagtgg aaaaatactc
    84061 ttcgactttc cctacaaacc aggccatctt gtgtttaata actataccaa atctaaggta
    84121 cctctaaatc taaattccat ttgtggcggt gacctccaat ttttaactct tctatctccc
    84181 atccagtata cataaccttg atacttcgac cacttatata tcgaacacac aaatacctat
    84241 ccattgcagg agtactacct aacttagttg ctacttgcat ctaaataaca gctgaaaaga
    84301 taggacttac tcttagtaaa gtatctgaac tattaatttt taaactatca tttttatcct
    84361 caactacatg cacatctgtt gcaacttcac tttctgtctc atccagataa atgattaagg
    84421 aatcgggaat tgcaatatct tcagctgacg ctggaatagt tgagctaaat tagtcatcat
    84481 atctttatta taaaataacc aacagcaaaa aatacaatga aaaacaaact tggaactaat
    84541 gtatcattaa taaatgttga aaaattcagc aactcattac tgtatgattt tagcagccca
    84601 accaacatat accctataaa agctaataag atggttagga atcctttaga atttttactc
    84661 attcatagac acttccttaa ataactttta ttatagaagg tattgtaaat aataatattg
    84721 acaaaaagtg actcaaaata aaaaaaacct tacattatac tggaatgaac tgtattgata
    84781 gtgtacctaa aagctctact gacataagat cgtgtaatcg gtaaagtaat tttattaatt
    84841 atacgggatg taatcaatta gagaataaac taatcataaa aggtactttt acattcataa
    84901 ttgtcgcttt gagattctac tttggttcac tatctgaccc aattgcacat tttcgatcat
    84961 tacaagtatt ggtgtcgtta gaacaactaa ataaaaacta gcggtagatt tttcagaatc
    85021 tatgctaatt tctgtatgga tgttccagtg atggcaaatt tctcttttca ttgtttttct
    85081 tgtcgcatga tatgcctttt tgtgttattc agttaaacta tagaaattct ttcctagaca
    85141 gatcttgatc ccaaatttta cgtttttgag catcgatata gtttaaaatg acattactca
    85201 tatctaaaga gtttagattt tttaggacta aaactgtcag ttgttctttt tcttctttct
    85261 gttaaagtat tgtcgcgact tttcgtatac gttaagatat gtcgtgaaaa aacaagtttt
    85321 gtgacacaaa aaaacgaatg acttgaggaa atcacctcaa tcattcgttt aaaatgctat
    85381 atattcttta gtttaagata cggaaattaa tgccatcgac cacactagta gaatgaacga
    85441 catttacttg gccttttttt aatttcgtta tgtttagcat ataaaaatat tatagagttt
    85501 acttacaatg cttaaaacat atactgtata atctgatcaa ttttagccat gtcttgcaat
    85561 ggtaagtttt ctattttttt gagttttcgt tccttaaaat caagagattt taattgtgta
    85621 ataattactt gtccttttat atctagctct tcaggtaatg agtaacgtgt cggtaaattc
    85681 tttatagtgg aagtaattgg acatatgacc gaaaacattg ttttacggtt aaattcataa
    85741 cgagagacga ctagtcctgg tcgtcttttt tgaatttctt ttcctacgga gggatcaaaa
    85801 tcaatccata caatatcacc ttttttagga atataaattc tttcttctga cactataaaa
    85861 tttctctccc ttcaggagtt aaatcttccc attcgtcttt ctcataatac tcggcctctt
    85921 ccccaccact aaatggatct tcaatttttg gaactaacgt aattgttcca tcatcagaat
    85981 acacaacgat atattcttgg ttttctgaag gtttctttcc gttatcagaa ggtaaagtta
    86041 ccactacaga acttccttgt aatctagatt ttgtaacaag cattatcatc actcccttaa
    86101 taaaagtata ctatataaca ctaagtaacg caaaattccc ctttgtaaac tatctagaaa
    86161 attgttttgt ttaaagtata tcttattgga tataaataga aataaattgt agccagttca
    86221 ttttttcttt aactaaaaaa ataatccaag aaacattgaa cctatggatc caaaagctac
    86281 ccaaatacta tagctaaccc cccgctacct tcaattttgc agataaaacg ctttgggaga
    86341 aaatttcaaa gacaacaggc catcctatca tgcccgatta taaacaaaaa gctggctatt
    86401 ccttttgctc tgacaaattt caattgggaa agttcacgaa actagcaggt gaagaagttt
    86461 caactgttcg gatcaaagaa tgcccgcttc aaatagaaac attggttcaa cgaatttcaa
    86521 ctagacaaga ctttgctatt gtagaacgtg agatcgtagc tatttttgta gaagaaggga
    86581 ttttacatga tccaactcat atcaatgtgg ataaatggca acctcttatc tataaattca
    86641 gagaatatac aactgccaac cagtcgttaa ctttgaattt tagattccaa gaattcaaag
    86701 agtcataatg ataaacatcg ttaggtataa ataaaaaaga ctcgcagcac gagtaaaaaa
    86761 caaatagaag ctatacatta gaaaggtcga ctgtgaccct atagatgcag tatatgcagc
    86821 ttatgagcat ttcttctgtt ctctttgttt ttgggatctg tgctgaagtc tttttcgttt
    86881 tttgccgctc tttctttgaa aaatcgatta tgttatacct tctccattac taattcaggc
    86941 atctgctgag taatgatttt tcgcgcaaaa gaaatatctg ttacccaagg ttcgatttgt
    87001 tcttcagtca agacaagcgg cattcggtca tggattggtg cgactgtgcg gttaggttca
    87061 gtagtcatta tgattgattc tgccattttt tcatcctgat ggctacgata aaaaccgcca
    87121 atatacacta ttttttcctt atttgaaaac ataaatttgt ctttttcttc attccactca
    87181 ttgggaaaac acaacgattt tgcaaaaatg gttgatgaaa ggtctttttt tcttctactg
    87241 tctctgcacg ggcattaatc atcaattgtc cttttttaaa tccggtaaat ccccacttca
    87301 tgatttccgg agtgaggatg ttttcttcct cttttcttaa cgtcacaaca agatttgacg
    87361 gaaaaacttc tccagctgct aattctgctg cctgcttcgg ttgtttcgtc tgggcttctc
    87421 gataataatt ctgaaggagc tctgactcta gatcaaaaaa ataacgacca cacatcctaa
    87481 tccctcccaa tctttttttc tatcatacac tgcaacaaga agttcgcacc aacaaaacgc
    87541 tttcaatttt tgtagaacta aaaaagttgt gacaagtgac aaactctcca gtgaatggta
    87601 ttctcctgcc aactcctcgg tcacaagtca caatattcaa caaacatgag aagctgcttt
    87661 ttgaaattgt tccttgtgac tcggagtgaa acggcaggct tacgacctct gggtaaacgg
    87721 tgttcaaaag ccagtttctc ggtattaagc caaatttatg caaaaatgta gaaagctatt
    87781 ttcacaaaat ttttcttaat actcgaaact aagcgacttt ttcacaacct cttccttaaa
    87841 cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tatgagcagc
    87901 tatttttatt tggctgttct tattacttga tgcagggcag ctttttcaca acctctccac
    87961 taaacggtgt tcaatcagct aaccttcggt attagctcaa aaaacggcaa aatatgagga
    88021 actattttgc cgtttgtttc tctaatactc aggtcaaagc gctgatttca caacctctaa
    88081 tacacggtgt tccagaagta gcttcttcga aaaataagcc gaaatttcac aaaaatttga
    88141 gaagcaattt tcgtaaattc cttcttattt cttgaagctg accacttctg tcacaacctc
    88201 taattattaa agaacctttt gcgaagttaa caatctttct ttgatcaatt gaaaattctg
    88261 cctaagtagt gatagatcct gtgtgacttt caacaataag atacttccct ggatttcagc
    88321 aatcaacgct ttggcttgac ggtctgcttc ttcatcggac agtttttctt cagaaagtgc
    88381 caggatattt tgtttcgtat acttgaccca ttgattgact aattctagta gcaacagacg
    88441 gtattcttca tccactgtac tcaactcaat aatcaaatta cctacaggac agccatgata
    88501 agtgatctgt gtctcatgat cagcgaaaat ccagtccaac atttcttcta atgcttcttc
    88561 tggctgtttt ccagcattta agatgtcttc gaacaattct gtctgccata cgtccatatg
    88621 cgcatggatc accgctagac aaacttcttt ttttgaagaa aagtaataat aaaattgacc
    88681 ttttcctgta tcagaagctg ctagaatatc tcggattgac gtttcatgat agcctttttt
    88741 ataaataaga tctttggtcg cttccaagat cttttccttt gttttcaatg atattctcct
    88801 ttttcatttc tcatagtcct atattataca gtaaattcat cattttttct tcttaatcgt
    88861 ttaaaaaaga ctgtgccaaa ttatctgaca cagccctcac tataaaactg ttctcatata
    88921 gctagatgtt cattgattca agaactgcga ggacaaaagc aattcctatc ttatgatagt
    88981 tgctctaata cttcctctgt tgtcatcact tgatctgcaa taaagccaaa gttcgtcaac
    89041 gctgcatcca ttgcttcttg gccaggagca ccaattgcat ctgtcgctac cacaacattg
    89101 aatccactct ctaccaattc acgcatatgg gaatcgctac acaagtttcc gttcattcca
    89161 ccaagaatta ctgtgtcgat tccatttttt ctcaattgga gcgccaaatc attgctttct
    89221 ggtccaaaga ttttatgagg agagctgatg atcgtatttt catccaaata aggtttcaat
    89281 tcttcgataa aatcggctcc tgaaccttct tccactgatt catattgact ttttctagca
    89341 aacatctgct gctcaagcat catatgttct cctgcaccgc caaattgcca tttatggtca
    89401 tgtgggtaaa aataatgagg agaaataaag agtttgtatc ctttttcttt tgcttgtttt
    89461 accatttcaa tcatattttc gatcgtattg tatttttcta agatatcttt tgtcaaacca
    89521 aagccaccgc ctgctggttt caagaactcg acttgcgggt cagtgagaac tactgctgta
    89581 tttttattat tgaacatggt ggattctcca ttcgttattt attttaatac atcatttaga
    89641 gcttcactca ttgtcggatg agaatagatt tgatctctca ataacgtata aggaagtttt
    89701 ccattcatag ctagcgaaat caagttgatg acttcatgag aatcttccgc atagatactt
    89761 gcccctagaa tcaagtcagt ttcagggtcg actaaaactt tgaatacacc tttaggatct
    89821 tctaatactt gtgctttagg gacaccgctt gtcatatact tgaataattt gtaattgacg
    89881 ccttgtgctt tggcttgttt ttctgttaaa cctacattgg ataaagtcgg agtgataaat
    89941 acactgtaag gcacagcttt ccggttattc gttgttcgtt tattctcgcc cttcaactga
    90001 tccataatga ttcgataatc atctagagag atataagtga actgcaatcc gcctttgacg
    90061 tctccaatcg cccaaatgtt gtctgcatct gtacgaaggt attcatccac agcgattgct
    90121 ccgcgatctg ttagtttaac atctgtattt tctaatccaa gtgatgctgt acttggtttt
    90181 cttccagttg cagccaaaac ttttgacgct tggattgtta cttcttggcc atcttctgta
    90241 aaggtgacgg cagctgttga ttcttggtct gctacttgat ctacagatac acctagatgg
    90301 aattcgattc ccgcatttgt catgtcttct aaaatcattt gcgcgatatc ttcatcttca
    90361 cgtggaagaa attcagaatg ggcatcaaga acgacaactt tagatccgta ttcattgaac
    90421 attgatgcaa attccaagcc aatatatcca gccccgatga tcactaattt ttccggtaat
    90481 tgttcctgat ccatcgcttg cgtagaatca atcaagtagc gacttgtatt caatcctttg
    90541 attggtaaaa tgattggttc agaaccagta ttgatgaaaa tccgttcgcc ttcaacaatc
    90601 actttttcac cattattcgt cacttcgatt tgatggttag aaagaaaacg tgctgtaccg
    90661 tccatcactg tcccagttgc ctcatcgctg atcatatgat aatttttggc gcgaagcatg
    90721 cccgtcaatt tttctttccg agcaacagcc tctgtaaagt cgattcctct ttctccattg
    90781 aaaatcaatg atttagaagg aatacagccg atgttgatac atgttccgcc atacatacgt
    90841 gttgactttt caacgactaa aaccgattca ccttttgaag ctaacgcctt cgctaaagtc
    90901 ttaccgccct ttccaaaacc gatcacaata ttttgatatt tttccatcat ttttccctcg
    90961 cttctttttt acctaccgat tggtacaaaa atatgataac cgataattgt ctattctcca
    91021 aatcatctgc tttatttgtc aaaaaaaacc agacaaaaag cggtcctttc acgtttttag
    91081 tctggttcga tttcctttat tcttctaaac aatcgttact tctacatcga tatttcctct
    91141 agttgctttg gagtaagggc agaattcatg cgcatcttct gcaatttttt gggcttcttc
    91201 ttcgctgatg ccatcgatat gcacttctaa tactacaccg atctgatagc cgccatcatc
    91261 taaattataa agagagacac gtgcttttac tgtggactct gctgtcattc ctgcttcttt
    91321 gatcatatgt tgtaccgccc cattgaaaca agaagcataa cctgctgcaa ataattgttc
    91381 tggatttgtt ccttctgcat ggattcctgg aggagtgatt ttcatatgca tcgagccatt
    91441 tggtgcctcg acttctccat tgcgcccgcc atggttgatc attgctgttt cgtatgcttt
    91501 tttcattgta ctgctccttt cgattgacca tttgctactt ggctataatt atagtgtatg
    91561 acaagtaagg cgctttctac aaaaattctg cttattcgaa taccagaatg ccgtcttcta
    91621 ctatttttcc aaaaaacaaa aaaatactac tcgtgaacaa cagcgtcata tttgttccaa
    91681 aataaatagc aatcttttct acataatctt ttatatgatt gattttaaga tacatatata
    91741 ccagaaagtt gaccccataa accaatactg ttaaaaaaat aaccatattc gttaccattt
    91801 tttcctcctt ttgctggtct ccctaccagc actcgattta accataccac tttttttgcc
    91861 gtccaagcaa ctagcctttc aaaaagactg gtttattctg ctgttaatga ttcaagatca
    91921 gaaaaatgtc cgaataattt tgctaatttt actaacgcca acttgttctt tccgaattca
    91981 tcattttcta tctgtaatac tagtaacggc tcatgtaagc ttaaacggat caaaaaccag
    92041 ccgtttccgt atggctcttc tagatcatat cgaatacctt cttcattttc cgggtcgaag
    92101 ttcatccctt tttcttcttc caacagtcgc ttcatttctt ctaatatctt gtttccttgt
    92161 tcgcgtggtt catcgctgaa caattttaat cggatttctt gtacttctac gggctgtttc
    92221 aactctttga tttgttcatc taatgtgata ccttttcttt ttaattctgg caaaagcatc
    92281 aggatctttg cgatgacata tgcaccatca tccagaaaat agttttcctt gaatgcagcg
    92341 tgtccgcttg tttcgatggc tagctgtgta tctttcccaa gacggttaag ttctaatgct
    92401 ttattgatta catttcgata gccggaaata taacgaactt ggatgcctcc tttttcttca
    92461 atgaatcttt gtagatgaga agaagtaggg gaattcgtca cgattcttgt tcctggatgc
    92521 tcttttaata cgattgtact taatactgcg atcaaattat ttcgattgat cactgttcca
    92581 gaagcactga caactgcaga acgatccaca tctgtatcga aaatgatccc aagatctgct
    92641 tcatttgcta aaacagcctg cttgatactt tccatcgctt ctttattatc aggatttggg
    92701 atatgattag gaaatcggcc atctggttcc aaaaattggg aacctgttga atccgcacct
    92761 aagctattca atactttttc agcaaagaat ccaccagcac catttccggc atcaacaatg
    92821 attttccaac catttagtgg tttgctttct agtgttccaa tccccttttt aatttttgtg
    92881 actaaatctt gcgcataagg tgtcaaaagg tctgcttttt ctacgcttcc agtttgttcg
    92941 ctttttattt tttgctgctg tgataggata aaagcaatat cttctttttc tgctcctcct
    93001 tctgaggtaa agaattttat tccattataa taatagggaa gatggctagc agtcagcata
    93061 accgcagcat cgcacgagaa ctgttcaaat tgagtggaca taaacatagc aggcgtagta
    93121 gctaattcga aatcgatgac atgtatccct tgttctttca gactttggat caacgcctct
    93181 ttcagtgctg gtccgcttat cctactgtca tgaccaatcc caatcgtcca ttttttattt
    93241 ggatcggttg atttcttctt tttctttatc cagtttgcta gtccccagcc gatctttttt
    93301 accatgtctg tcgtcaagtt tacttcatat ccttcaactg gtaatgcgat tcctcgaata
    93361 tccgatccat tttgcagcgc tttcatatct ttcatataaa agtcctcctc atttattccc
    93421 tcattttttc cagcttttct gcaaatcgct gtgcttcttc ttctgagcgg caaataataa
    93481 tgaatgtatc tacaccggcc atcgttccga caacttcagg gtaagccact tcatctagcc
    93541 aattcgttac cacatcggca ccatttcgtt cagtcaatac gataaccatg aactgaacag
    93601 actggatacg caaaacctcg cgtctaattg ctgtacgcaa acgttcttca tttaaagaaa
    93661 cagatggctg gttaaataat gtatagcgta ctattttgtt ttcattttga ctttttacta
    93721 acttcatttc tcgaatgtct cgagaaatcg ttgcttgagt cacatcggcg cctgcttcat
    93781 gcagccgcgc aagcagctct tcctgtgtcc caataggttg ttctgtaatg atctggcgga
    93841 tcagtgcttg tcgctgtttc tttttcatat tagacacctc tcaatgttga ttatagcaaa
    93901 agataagtaa tatttcttca tattttggta ttttttactt ttattttttg ttttcattca
    93961 ggttgctaac ctttttctat tttaacacgc aaaatcgtct tcattttttc aggtgctgat
    94021 tttcttggat cgctgatgta aatctctttg tgttctttag aagctctttc atagccttct
    94081 tttgcgatga atgcttctaa tttctcaaac gttgctggtt cttcggcata gggcccgacg
    94141 tgtaagattt gggcacaaag accttcttcc atctttttga atactacttg ttctttcaag
    94201 tcttccggaa gtttgctaga acgctgaatg gcttcttgtg ctatcgcttc tgtaacaaag
    94261 tcaggctgtc ggatcatcaa ttgataagaa aaatgttctt ttttcatcac tggttcatgc
    94321 aaatactttt cttgcagtcc ccattgtcct tccagtggat agacagtata catctgataa
    94381 tcaggaatca gccaattttt tttaggcgac atgcgtattg catagctgac tgcatataga
    94441 caggctactc ttcgtttaaa gtcttcctga ttcgggtcgc cgatccctct gatgctaaag
    94501 aatgattttt taggaacctc tagtatttgc gggctttttt tcatactata gctcttgtct
    94561 ttacgccatt caattttttc catttttctt cctccgcgaa attccattta gttatttatt
    94621 atcatacctc tttttgagtg acttggctaa tcgtgttgac actatttttc agtttgtgct
    94681 agaataagtg aagtaaataa atcgtacaga taacacgttt cggcgtgtcg agagagaggc
    94741 ggtttctatt tttataatag aaatcactct ctttttttac gaaatttttt agaggtgatg
    94801 taaatgacaa aacaaaaaca gctgctttta gtacctgcag taattgcaac agggatgatg
    94861 tcttttgcgg gcgtattgat cgagacggcc atgaatgtaa ctttcccaac tcttatcaga
    94921 cagtttgatt taacgactgc acaagtccaa tgggtaacaa cgatttatct tttgatgatt
    94981 tcgatcattg ttccgctgtc tacttatttg aatcgcaatt ttagtctcaa aaaactcttt
    95041 ttagcttcaa atctgctttt cttggcaggt ataatgatcg atttcttctc tcctaccttc
    95101 atggtcctat tgtttggtcg attgctccaa ggtgcagcga caggtatcgc tcttccgttg
    95161 atgttccata ttatcttgac atttgccccc ctcaatcgac gaggcgcgat gatgggtgtc
    95221 ggtactttga caacggccat tgctccagca attggcccca cttatggagg cattatgact
    95281 tcacatttta catggaatca tatcttcctg tttcttgtgc ccgttttgtt tctttctttg
    95341 attatcggct ggtttgctat tcccgagatg gcagtacaaa aaagtggtta tttggattgg
    95401 ataagcgttt taggaatttg tcttttgttt agtggaagtc taacattttt gagtacgttg
    95461 ggaacagttt ccagctggat tgctttaatc atcggcggta ttggctggtt ccttttttac
    95521 tatcgaagta aaaaagtgga gcatccactg atccgactgt ctattctttc aaataaaaca
    95581 ttccgcttgt ttttgattgg cttcttagtt tatcagtttt tattacttgg tgtatctttt
    95641 gtcttgccga atttccttca gatcgttcaa ggaagtagtc cttttgtcgc tggattagcg
    95701 atgcttcccg gcgcagcggt tggtgctttg ctttctcctt tttccgggaa aatgctggat
    95761 caatatggtc cgaagaagcc aatttttgct gggctgattc tttctttgat tggttggcta
    95821 gcattattcc tactcatagg acacgcttca gtgggtgtat tgattgcttg tcatgtgttt
    95881 tatatgatcg gtatcggatt atcttacagc aatatgatga ccaccggaat gaatgcactg
    95941 aatgaagaac tacaaggaga cgggaacgca atgttcaata ccttgcagca gttttctggc
    96001 gctgtggcta cttcattagt agcggtcatt atcaattacg tccagcatca tacttcccat
    96061 aactatgaag tgtctactac attaggatca aaagcagcat taggcgtctt gttgctgttg
    96121 cttctcgtaa gctttgctcg attcgcctat tatctgttct ttgctaaaaa agcgtagatt
    96181 ccatatacgg caggtgttgc atctgccgtt tttttgtgtg aaaatggttg tttgtaaaag
    96241 gaggcttttt tatggaaaaa attgccatta tcggtggcgg gatcattggt atgaccctag
    96301 ccagttactt agatacatca aaattcaatg ttgctttatt tgatgaaggg acaggacagg
    96361 caactaaagc tagcgctggg attatctccc cttggttgtc gaaacgcaga aacaaacaat
    96421 ggtatcgtct ggctaaagac ggcgctgctt ttttccctaa acttataaaa gatttccaac
    96481 ttgatcaaac gatttacgca caatcaggga cacttttgct tcgacctgaa aaagatttag
    96541 ctgaattggc tgttcttgcc gagaaacgaa aagaagaagc gccagaaatt ggaaacatcg
    96601 aatggctttc acctgaacag acatctcaag cacttccgtt attgaaacca gcagtttcac
    96661 tgcgtatcag tggtggtggt cgtctggatg gaaaagcata tttagaacat cttggtcagc
    96721 gtttagcaca aaaacaaatg gagcagatcc aggcaaaagt cactttgcat aagaagagcg
    96781 attcttggct catcaaggga ccgtttggag aatacacagc tgatcgtgta attttgacac
    96841 ctggcccggc acttaagcct ttattacaag aattaggcta tgctgcagat atacgtccgc
    96901 aaaaagggca gctcttagca tttcagacat cttataagat gagtcaagac tggcctgttg
    96961 ctatgcttga cggagaagct gatttcattc ctttcatgga tggaaagatc cttttaggtg
    97021 ctacccatga aaacgatcaa ggctgggatt tggctcctac tagcgaagct tataagggat
    97081 tgactaagag tacagaacag ttcttgactg atccagatca gataaaaaac tggccatacg
    97141 agttccgtgt aggtacccgt gcttatacgt cagatttttc cccatttttc ggcgtactgc
    97201 cagatgatcc aagcttactg gctgctagcg gtctaggctc ttctggcttg accacaggtc
    97261 cttatatcgg ctatctatta gccaacttct taaatactgg tcattggcct acggaagatt
    97321 atcaaaagga catctccacc tatattacga aaaatccatc atagaaaaac agctttttca
    97381 agtaaggatc ccgagcgata ttgcgcatgg attacttctt gaaaaagctg ttattttagt
    97441 tcaatttctg aatcaaattc tccaaacttt cttttgcttc atctggcaag agatcttttc
    97501 ctatctgagc ttcaatgaat cgtaaacgaa tatcaagtcg ttgtttcacc agatttttat
    97561 aggacgtatc ctcaaaagaa acaggaaaat ctggtatagg taaatagtgg atgtcttcaa
    97621 atggaccaaa cgacttgaat tctgccgttt gttgcacgat tctttcaacg attgacaatg
    97681 tcgtttcagg tttgattttt ttatcatcga aatatccagt attcaggaca tagcaggctg
    97741 tttgctgttt caaaaacaac tctcgaaaag cttgatagtc ttccctaaga ggatagacac
    97801 ggaaaggatt agcaaatggt tcaatgacta gctcatctag ctgtcttttt gtagtgatat
    97861 tttccgcgtc tgatcgtttt gttgctaatg ttgcaccaaa agacgctgct aaaactgggt
    97921 cattgatctt gataattggc ggaagcgaat catctttcat gatccaaaaa acagcatcga
    97981 tcttttcgct aagatgatcg actcggtcgg gtgtcgcata acgtgatttg actgtccgcc
    98041 catttccgtt tcgtatatct cctgttacta ggactttttc tcctttactt gtacatgtca
    98101 cgcccacatt ctgacaagta aggaaagaag aaatggccgg atcatcagac ggatagtctt
    98161 gtgttttatc aaagtaagaa ggttccaagg cagtagcaaa accatttttt cgagaaataa
    98221 cgaaagcatc gtcatgcaag atcgaaacag agtgaccttc cgtatgtttt gctaaggtaa
    98281 tcgttgattt tccagaaccg gacaacccaa atacagccat cgtataggtc tggtcattac
    98341 tagcatattg tttcatccca ccgtggcagg caataaagcc attgcgattt cccaatgccc
    98401 aagcaagcgt caaagtcgct ttttttaatt ctccaaagta acgtaatcct agcacagccg
    98461 ctgtattatg gagagcatca aacaaaatga gtccatttgg aaatgtttca tgtgtccatt
    98521 cgggatcaca aaagatataa agatctccct catcaaagga aacagacttt tgataagtct
    98581 ctaagatctt cgaattcgct ggctgaaaat tcagcaaata agaatacaaa ttgttctcaa
    98641 atccttctgg aatcagcaaa tgactttgca cagaaaattc ttcagatagg ccaacgatta
    98701 cttttgtatg gtaaaactgg cgcttgcgac tttgatacac agcttctctt aaaattttct
    98761 cgtatttgct ttgttccttg tctaagtcct caaagatccg ccgagcactt gctgttcttc
    98821 ccacaatgct tccatcattg aatactagtg tcctaacatc agctggtaaa tctagttctt
    98881 cagcatgtga gattgttaaa tctgtgatga tcgttcctgg actccctttt gctagttgat
    98941 aagctgtctt cctatcaaaa acttcatgaa cattattacc gtaaaatgtc gtttctacaa
    99001 tcgatcgaat actggataac agtggatttc cacttgtgat ttcgtttaat tcgagactct
    99061 cttttgtact catggctcct cctcattccc taaacaaaaa aacgttttct ttattataca
    99121 ttattcgagt ttttatttgt actgctgcgc tgtgggaagc aaacgagtta tttttcacac
    99181 aaaaaaaccg agaacttgaa taaacaagtt tctcggtttc atcattttcc ttttatcggc
    99241 ttagtaccag ccgtttgcta accagaatgt tttagcagca tcccatgaac cataacgaga
    99301 tgttacatat tgttctgcta cacgttcttg attggcagct gaatagtcgc cgtttaagta
    99361 tgaagcatct aattgataac ggccgatgta acgtccgtta gtagctgtgt atgaaccgcc
    99421 tgattctttt tgtgcgatcc attcttttgc agagcttgaa gttggcgctg ttgcagcagc
    99481 tggggcagca ggagctactt caactgtttc aacaggtgca acgtatgtat gttcttgcgt
    99541 tgctgtttca gttgtagatg ctgtattttc tgttgttttg ttttctgttg ttgctgaaga
    99601 atcatttgaa gttgggattg ttaattgttc accaacataa atgcggttga tgtttgcgat
    99661 cgaatttttt tcagcaattg catcgatcat tgagttgtct cctgcaaatt tttgtgagat
    99721 cttagataat gaatcacctg attttactgt ataaacttca tcagcgtgag catttgtagt
    99781 tcctacaaac attgcagtag caccagcagc aaaagttgta cctaaaacaa ttttcttaaa
    99841 tgaattcata ttaaactcct ttttttctcc gttttttatt ctttcgacgc tattaacttt
    99901 atcatttaga aatatttcat aggtaaaaga aacatgacat ttaatgacaa aataacgaat
    99961 tatttaatat ttgtaacatt taaacaaata tttttttgat acaaaaccat aaaagccttg
   100021 ttgtataagc aaagtaatcg tttttctatg tttttttatt tttgaatgaa aaacgcagat
   100081 tctgtaacat tcactgcaat aatccataaa aaaaagcaaa aaaatttttg atttttatca
   100141 aattctctta aaaaaatgta aaaaatacaa aaaaaccagt aattgttaca acaattactg
   100201 gacaaaaact ttgaataatg ttaactattt ttttatttta actttctccg caataatttc
   100261 tgggcatgtt ccaattcgtt tataacgact tcttctgttt ctttagctaa tatttcatct
   100321 aatacatcaa gccatttttc cggttctttt gttcctagac gtccaatagc ccaagctgct
   100381 gttcctctga tgacagggcg gacatctgtt aaacattctg aaatctcagg caatgccgtt
   100441 cgatcaccta gattagctaa agcaatcaat gcgtttctct gcaaaggttt cttcccacgc
   100501 catgaaccag ctaaatgccc aaattgctgt ttgaagtctt tattagacat cgaaagcatt
   100561 ggctttaatt ttggatatat ttcgtctact tttggttcca tctcttcatg aaaatgaaaa
   100621 tcttttcctt gattgtaagg gcagactaac tggcagatat cacatccata aatgacattt
   100681 cgcatttttt tacgatattc ttccggcatc atcccttttg tctgagtttg ataagacaaa
   100741 catcgctggg cattcattct tccgtcacca agcaatgctt ttgtcggaca agcagtcacg
   100801 cagcgcatac agtcaccgca accaaattct cctggtttat caggctcaaa tacaatatta
   100861 gtaacgatct caccaagata gacaaatgaa ccgaactctt cagtgatcaa caatccgttt
   100921 cgtccaataa atcctaaacc agctcgctgt gctacagcga catcgatcag ttctccagta
   100981 tctacttgcg gagctagacg ccattcctct tctttttgcc atttttctgc tcttgtttgg
   101041 atgaattcga tcaatcggtt caaacggtct ctgagtatat catggtaatc gatcccccaa
   101101 gaagcacgag caaactgccc gcgtttttca tccctaggca cttcttcatg gatcctagta
   101161 ggatacgcaa gtgcaatgga aatgatcgat ttcggctgat caaatgtcat ttctggataa
   101221 agacgctcat cgatatttgg atgttcaaag ccagaagtat ggccagctgc tttttgttct
   101281 tccaacgatt cttttaatga atcaaaaggt tccgccgtgg tgaacccgat tttgtcaatt
   101341 cctaatcgtt tgctttcttg tatgatttct tcttttaatg tcatggtctt cctcgcttgc
   101401 tgttaacggc tgtataaccc ataatatagt ttttcttttt tcagctggac aaactggatc
   101461 tgctgatcgg caatcttctt ttcttccatc catttttttc ttgcagcaaa tacttcccaa
   101521 taatttgttg aaattaattt tcttttgtta tctaatgcat taaaaaaatt caatgaaact
   101581 ggttttgtac ttaacagttc atggagcctt acctcttccc atggcgaaaa ctcagacaga
   101641 tcgcgggaat acaatacttc ttcatagaga tttttttgct gtgtgtacgt gaatgtttgc
   101701 gggattttcc caggcctagc aatttctact agacgattat aaaacatatt cattaatttg
   101761 ctgttggcaa taaattgact tttataatag gccgactgga tctttttgat tactccttct
   101821 gctttgatga ctgaaaataa tgcaggccat gctttgacgg ttatttcgtc gttttgttta
   101881 actaatacgc caggtgtgaa gccgactgga gaaaggaaca caaaataacc gataccggta
   101941 ttttcatcta aaggctgaaa ttcatcaaac aaccatttgc ctatgtacag ctcttcatct
   102001 ggttctgttg tctcattttg atttgctatg aataatttag ctaattctgc ttcaagaaat
   102061 tgaaggtctt gatccttgtc ggtattttcc tgctggctga tcaatcgaaa gacttcttct
   102121 ttaatcgtat atttatcttt acgtgtaaaa ttcatagcca caccttcctt ccttactcta
   102181 actataacgg aatttcttca aaaaaggtat ctgtacgacg aaaaacagca taattttttt
   102241 tcatatctct tataaaaaat gcaaggtctg ctcctcaagc tagaccttgc acttttcagc
   102301 tttcttttgt ttgtgacaaa ccttcatgga tcgtttcaat attccatttc atcatctgat
   102361 agtaagaatc tccttgttct ccttcttttg ctatggaatc agtgaacagt ttatcataga
   102421 ttttcaaacc cgtttctttt gctacccgtt ccatgcttct tgagtctaca ctggtttcca
   102481 cgaataaaac cggtacttct tttgctctta tctgatcaat gatcgctttc atttgatcag
   102541 gcgtaccttg actttctgta ttgatctccc atatataagc tgctggcaaa tcatatgctc
   102601 gtgaaaaata cttgaatgcc ccttcacttg ttactaataa ttttttgttc tcttcgatag
   102661 aagcaaaact ttccttcgct tgtgtatcta attcttttag tttttccaca tatgcttctg
   102721 cattttttta tagagtgtcg cattttctgc atctttttca gagaatatac gtgcgatttc
   102781 ctccacatat tttattccgt tagataggtc tagccaagca tggggatctg cttttgtatg
   102841 ttcttcaccg ctagttaaat aaagaggttc tacatttttg ctaactgcaa aataatcttt
   102901 tccttcttct tttttagccg tttccatcaa gttatcgaac cagctgttac ctgtttcaag
   102961 attcaaaccg ttgtataaaa taacatctgc atcgcttgcc tttttgatgt cttctggtag
   103021 tacttcatat tcatgcggat ctgttccgac tggtacgata ctgtggatat ctatttgatc
   103081 tgttccgacc tcttttgcca tgtccgccaa gatcgaattg gtagccacga ctgacaactt
   103141 ttctttactt ccttcatccg cttggtcaga agcctgcttt ccgcaaccgg ctaataccaa
   103201 gaaactaact gccaagatta aaaagagtga tttttttgtt ttcatctatc tgcttccttt
   103261 ctgaaataaa attccttttg ttggagaaaa taaaaaagca aggataaaaa atgcggtaca
   103321 tgctaacacg atcgtagctc ctgatggcca attgtaacta taactgaaaa acacaccgac
   103381 aactgcactt agcataccga ttcctgcagc tgtaatgatc attttcagta aatggttcgt
   103441 tagcaagtaa gccgtggcgg ctggtgtgat caacatggca atcaccaaga ttgttcctac
   103501 tgtctgtaaa ctgactacag ccactaatgt caaaaagaac atcaaaagat aatggatcag
   103561 cgatgtgttc agcccataag cttttgccat tgtcggatcg aatgatgtga tcttcaattc
   103621 tttataaaag aaaaagacaa atatcaagac gattccacta acgagtgctg tcagcaacaa
   103681 atcgctttcc ctaacagcta agacattccc aaataaaata tgatacaaat ctgtcgcact
   103741 ctgggcatat gaaatcaaga taatccctaa tgcaaaaaag gagctaaaga caattccaat
   103801 cgctgtatca tttttcaatc ggctccgctg agtcacgaaa ccaatcactg ctgctgttag
   103861 catcccaaaa gcagtggctc caaagatgta actaaaacca aacatataag aaatggctac
   103921 acctggaaga actgcgtgag agatagcgtc tcccatcaaa gacatccctc gtaaaataat
   103981 aaaagaaccg atgactccag aagcaagtcc tacaagcatg gaagtgacca aagcgtattg
   104041 caggaattga taattcatta atccatcaat aaaggattgg atcatttttt ctctcctcct
   104101 tttactaaat gtctgatgat ctcaccatag gccaattgaa ggttcttcga tgtaaagact
   104161 tcttgtactg gaccggaagc gatcagctgt ttatttaaaa gaataacctc atcgaaatat
   104221 tcttctactt tatgaagatc atgatggacg atcaaaatcg tttttcctga attcttcaat
   104281 tcctgcaaga tgtcaaagat ctttcgttca cttaacgcat caatccctac gaatggttca
   104341 tctaaaaaga tccattctgc tccttgggct agagctcttg caataaaaac tctctgaagc
   104401 tgtccacccg atagttcgct gatctgtctt ttggcatatt cttccatccc tacttttttc
   104461 aaagcttgtc ttgcacgttc tttttctttt ttcccaggtc tttgtccaat tcgtaaagat
   104521 ggatatgttc ctaaaagtac aacgcctaat acatcaattg gaaaggaaag atccaattca
   104581 cttcgctgtt ccacgtaggc tattttttta cggactgagt ttaccgactg tccagaaaag
   104641 gtgactttac cagtagtagc tggtatcaac tctagcaaag atttcataaa tgttgatttt
   104701 cctgcaccgt ttggtccgat aataccggta attttttgtg gatttatcgt caagttgata
   104761 gttttcaaaa cagttttccc ttgataagcg gctgaaaggt cttgaattac aatggccgta
   104821 cgttccaaat cttacactcc tttttaggtt tacctaactt tttatttaaa tatagtttaa
   104881 ctaaaatgga aagcattttc aagtagaatg atgaaaaagt ttttttcgaa ttttcctcgc
   104941 attttatgaa aattttctgt agaatcacat caagagttca ataaggctaa cctaataatg
   105001 aaaaacatgt gttgaaacgt ttgattattt tttcttgttg actcaacaac gaaaggagtt
   105061 tttgtatgga agaagaaaag ttaactcgaa gtcttagtgc ccgtcatatc caaatgatcg
   105121 cactaggtgg aacgatcggt gtcggtctgt ttatgggtgc ctcctcaacc atacgttgga
   105181 cagggccctc agtgatggga gcctatgcga ttgcaggatt ctttttgtat ttgattatgc
   105241 gtgctttagg cgaaatgctt tacgttgatc cttcgactgg ttcttttgca aattacgcga
   105301 gcgagtacat ccatcctgtg gctggctact tgaccgcttg gagtaatatt tttcaatata
   105361 ttgtcgtagg aataagtgaa gtgattgctg taggatctta tatgaattat tggtggcctg
   105421 atttgccggc aattattccc ggaatcattg tcgtcttgtt tcttatgctg gcaaatctta
   105481 tttctgtcaa ggcgtttggc gaattagaat tttggttttc gatcatcaaa gtcataacga
   105541 tcattttgat gatcattgca ggtcttgggg taatcttatt tggatttggt aatcatggtc
   105601 aggcagtagg gatttcaaat ctttggaaaa atggtggatt cttcactgga ggcgtcaaag
   105661 gatttttctt tgcattatcg atcgttgttg cttcctatca aggaatcgaa ctgatcggaa
   105721 tgactgctgg tgaagcagag aatcctaaaa agacgatcat tgaagctgtc cagtccacta
   105781 tcggtcgaat cttgattttt tatattggtg ctatttttat cattgtgagt atctatccgt
   105841 ggaatcaatt gagtgagatt ggttcacctt ttgtacaaac tttttctaaa gtcggcatta
   105901 catttgctgc aggactgatt aattttgtcg tgattacagc ggcattatca ggttgcaatt
   105961 cagggatttt cagcgcaagt cgtatggtct atacacttgc cataaatgga aagatgtcta
   106021 aaaaatttct gaaactatct cgtcacggtg cgccttttta tcctgtcgta gcaatctcag
   106081 gtggaatctt aattggtctg atcttaaatt atcttctacc aatgttcatc aaccagtcag
   106141 aaaatatttt cgttttcgta tacagctcaa gtattttgcc tggtatggtt ccttgggtag
   106201 tgattttgat cagcgagatt cgcttcaaaa agaagcacgc agataaaatg catgatcatc
   106261 cttttaaaat gccactatct ccttatacga attatgtgac acttgctttt ttagctatcg
   106321 tattgatttt catgtttatc aatcctgaaa cgagaatctc attgattatt ggactcgttt
   106381 tcttgcttta catgacgatc cattactttg tacgcgaaaa aagaaccgga aaataaaaaa
   106441 agaacgaagc ttcaccttag tggaagcttc gttctttttt attgctttta tcaattcaat
   106501 tttagcgtct caccgggagt caggaaataa ttctccatgc tcatcccatt cagcgacaag
   106561 atcgtttcta ctggtacgcc agttcgttcg gctatttgat ttggaccttc tccttccaaa
   106621 actacggttg tcgcagcctg tgaagtcgcg ctgttggtat tagtttcaga ggaatctgtt
   106681 gtgtcttgtg ttgttcgagc ttgcatttca gaagcttcta ccgactctgc tgtctcagaa
   106741 tcagaagatg ttgtgtcttg tgtgcttgtt gactctgctt gaagagaggc gctagtctgc
   106801 aaataaatat cggaaatctt agcgacatga ttcgtataat tagccgataa ttgattgatc
   106861 aaagtatcta agtctacacc gtctttattt tctgctgcct gatacgctgc acgtaatttt
   106921 ctgatccctt cgtcggagat tgcttgaagc tcacgtgctt tttggttagc aactgctgat
   106981 aaaccagcta ttccctcttg atttccctga atttctgtct ggtattcttc aatcaatgca
   107041 ggcgtctttt cttcgatctt tttcgaataa tcatttacga ttgcttgaag ttgctctggc
   107101 aaaccatttg ctgttttttc ttcagaagtt tgtgtctctt ttgttttagt tgatgactca
   107161 cttgtttgtt tcgtctctgt tttctttgtc gttgtttccg ttatggtcgt acttttcgct
   107221 tctgacgaat tttttccatg aaaatataga cccgcaactc ctcctgctat gatcaaaaac
   107281 acggcaactg ctgccccaat catgatcatc cgcttacgag ctgcctgttt ttgctgtctt
   107341 cttcgggtca tccgaacatt ttctccccac tcattttcat catacatttt tttcaccacc
   107401 aatttttatg tataatagcg ttatcaaacg cttcatattc ttattgtagc aaataattgt
   107461 cgctgtgcac atttttatct ttgttattta taagaaaatt tcaccagttg agatgattcc
   107521 aagattgtcc gtcgatttct ccttgcagct gcattgttcg ttcgtctatc tcagccatca
   107581 gtttctttat ttcatataag agcgcacggt cttgatattc tgatttttcg cttaattcat
   107641 ctaattgttg gatcagccaa tcatttgtca taatgaagtt cctttcattt cttgcagtgt
   107701 aaaggtcaag tcttcgatct gctcttttgc ctcagtcagt gcttctacga tatatgcttg
   107761 tttttcagat tcttcttcct gcattttctg attttcctgt actctttgaa taaaccagtc
   107821 aatccgctga gtcagcgatg gtttgccttc caatgagaga tactgctgat aagcaattag
   107881 cttctcccaa cgtttttcct gggataaata cataaattgt gctaaaacga atggcggaag
   107941 ataggtcata tggaatttat ttgcgattcg ctgatacggc ctcaaaaatt cggaaatcgt
   108001 atattcttct tttcctccag cttggtattc tttttccgcc acacctgttg tcaatacgat
   108061 tcctagttct ttccctttta atacatgtgc tgctcgttcc aagacattat cttgccaaat
   108121 ttttaaatga gcaggagaac tataccagta aaacggaaac tggaaaatga tccgatcatg
   108181 ctgggccaag agctgtagtt cagtctctat atctattttt ccgtctggat aacttgattc
   108241 caaatgatgc caagtagctg gtaaaccagc agaagcttct ttgaaaaatt gctgatttaa
   108301 agattcttcg atcgttggat ggctaatgat gataagtgta cgcatccctt ttcctccttt
   108361 ttagtcttcg ctttacagtg tagcataacc gccacaagtt tcttttgccg atgcttgtca
   108421 ttttaaccag actaatcagg ttgtccaaga aactgcggtt tgtttttcca actgtttttt
   108481 caaggtatcc aaagcaatat tcttaaaatt ttcgtttttc atacgtttac gatagttcgt
   108541 agccgtttct ccggtactct ttttgaacat tcggctaaat acgactagac tattgaaccc
   108601 tacttgatag gcaatacttt ccacggattc atccgtcaga gaaagaagaa acgcccctcg
   108661 attgatccgt accccgatca aatattcctt gatactggta cccatatgat ttttgaatac
   108721 tcgcgacaaa tggctccgat tgaccgctaa atgctgggcg atttcctcaa cagacaattt
   108781 ttcagcataa tgtgcctcga tgtatttgac tgtttcaaca gctaaagagg aatgaacctt
   108841 ttgtacacca ccgctgacct ttccgccatc ttttaaaagg actgataaaa aacggtaggt
   108901 taatgctgtt aactgtaatt cattttccaa ggtttcttcc gtatctttca tgcattctaa
   108961 aataatgtcg atatattttt gtatgtcaga agagaccatc gtgtattggt cttctctgaa
   109021 aagcgactgc cgaatgattt cttctgcagc actcccacca aatgaaagcc agcaatacat
   109081 ccacggatct tctccatctg ataagtaaaa cgtcgagtct cctggacgaa tcaagaacag
   109141 atcacctttt ttcaattgga attgttgatt tttcacatga taagatcctt tgccttccat
   109201 cacgacatgc aggatgtaat cattgcgaat agcaggacca aaagaatgaa acggcatcgt
   109261 tttagagaaa ccacaaaaat caaaatacaa ttctttttct acttgttgat gttccttttt
   109321 taaaaaaatc gattgctcca cgtctatccc tccttactcc tttagtataa tgcaacaaaa
   109381 agttaaataa aagtcacaga aatatattaa aaaggaagcg atttcttgtt aagtttaagt
   109441 cattaaaaga tctttgttat tcgttgtaac cggtttactt agtattatat attgaacagg
   109501 agaggaatac agattatgaa aagcaaaatg atccaacgtg tgtcctacgc tttaggcgct
   109561 tttggacacg acacattcta tgttacatta agcacttatt ttatggtatt cgtgacaagc
   109621 cagatgttcg caggaacaga taaggcaacg aatgcaaaaa tgattgctac agttacaagc
   109681 ttagttgtag gtatccgctt agttgaaatt atttttgatc ctttgattgg tggcatcatc
   109741 gataatactc gtacaaaata cggtaaattc aaaccatggt tagttatcgg cggcgttgtt
   109801 agttccgtac tcttggtagc aatctttacc aatttctttg gcttagctac tcataatacg
   109861 actttattta tcatattatt tgcaatcgtt ttcatcttat tggatagttt ttattcattt
   109921 aaggatatcg ctttttggtc aatgattcca gctttgagta cggaaacaaa ggaacgtgaa
   109981 aaatttgcta cgtttgctcg tttcggctct tctctaggtg caaatggtac tactctagtc
   110041 gttgtcccta tcgttacttt ctttacctat cttgttactc ataaacatat tgaaggcgct
   110101 tcaggctggt tctggttcgg tgtgattgct gctgttattt caggcggtac tgcgattatc
   110161 actgccttgg gcacaaaaga agtcgatact gcgatccgtc agcaaaatga aaaagctggg
   110221 atcaaagatg tgttcaaagc agttgctcaa aatgatcagt tgatgtggct tgcccttgct
   110281 tatatcgctt atgcgattgc caatgcagca acaactgccg tattattcta cttcttcaaa
   110341 tatgtacttg gccaaccaac tgaattttgg atcgttggtc tagttgctgc cttacttggt
   110401 ttagtagctg ttccactatt cccaatgctt acacgcgtca tctctcgtcg ctacgtttac
   110461 cttggaggga tcgcaatgat gatttcttct tactttttct ttacgatcgc aggttcaagt
   110521 ttgccaatcg ttatcatcgg gctagtattg ttctacttcc ctcaacaatt gattttctta
   110581 tccgctttga tgacgatcac agactctgtt gaatatggtc aatggaaaaa tggtatccgt
   110641 aacgaagctg ttactctatc aattcgccct ttactagata aaatcgctgg tgctttgtct
   110701 aacgggatcg tagggtttgt cgctatcgct tctgggatga ctggtaatgc tactgctgct
   110761 gatatcactg ctcatggcgt aacgactttc aaagcttatg cattctatgc tcctgctgct
   110821 ttgatgattt tctccgctat tatttttgct tggaagatta cattgacaga gaaaaaacat
   110881 gcacaaatcg ttgagaaatt ggaaaacaaa ttggctccag ctgatacaat ggaagattaa
   110941 cttcacgatg cagtagttcc ttcccattaa gaaaggatct tgaaaatgaa gattacagaa
   111001 aaagattttg gccaaggtta tcacttgata accttggaga acaaaaacaa gctagcactt
   111061 tctatctctg atttaggtgc tagaatcgtc agtttaaaat caaatgatcg agaattagtt
   111121 ttgggatttg acaccgctga agaatatatc gaaaaagatc cgtatatcgg tgcttctatc
   111181 ggtcgcaccg cagggagaat cgaaaatggc cgcttttctc tcaatggaaa aacttaccaa
   111241 ttagccacag atccaaaaac tggacataat ctgcatggtg gtgctcctgg atttgaatta
   111301 aaaaaatggt cttatgtcat tttgaatggc gaaaatgaag cttctgtcat ttttactact
   111361 acaagtcccg acggagaaca tggttttcca ggtacaatgg atgtggaaat ccgctatact
   111421 ttgacaaaag ataatatctg gcgagtgacc tctcgcggca ccagtgacca agatacttta
   111481 ttcaatccga caaatcatgt ttacttcaac ttgacgggag atgcttctca gtcaatcgat
   111541 caacatgagc tttggctcaa tagcgaagct tatgctcctt tgcgaacaga tagtattcct
   111601 ataggggtaa aagaaaatgc tgcaggaagt gctttcgatt ttcaaatacc taaaaaatta
   111661 gcgtccgttt ttgctagtga tttggatcaa aaaaatcttg ttgacggaat cgatcatcca
   111721 tttttcttaa aagaaaccgg cttgggtaaa gaagccgctc gcttgactag ccccgataaa
   111781 agaatccaag tagatattgc tacagatgct tctagtgtgg ttattttcac tgcaaatttc
   111841 ggcacagaaa caccagaaat gcgcaaccga aaactggcac atcacggtgg catcacattt
   111901 gagactcaaa cagctccagg tgcagagcgc ttctcagcat ttggttcgat tcatttaaaa
   111961 gccggatcag tatttgaaac agtaacagaa ttcaaaatca aaacaagaaa ggaataactc
   112021 atcatggaaa tcaaaagaag cttaaacaca aaatttgccg aaacattcgg acctaaaaaa
   112081 actacacaat acttctcacc aggacgcatc aatttgattg gtgaacacac agattacaat
   112141 ggaggccatg tcttccccgc ttccatcact tatggaacgc aaggtgtagc agcacctcga
   112201 gacgataata aaatattagt ttattccaca aactttgacg atatcggtgt cattagtttt
   112261 actttagatg agctagaata tgataaaaaa gcaaactggg caaattacgt aaaaggaatg
   112321 gtccttaaat taaaagaagc tggacactca atcgatcatg ggtttgagtt attagtggaa
   112381 ggaacaatcc ctaatggtgc aggactttcc agtagcgctt cattagaatt attagtaggt
   112441 gttgtattag aagatctgtt tgatttaaaa acagatcgct tggaactagt ccaaacaggt
   112501 aaaaaagtag aaaatgaatt catcggtgtc aattcaggta tcatggatca gtttgccatc
   112561 ggcttcggtg agctagatca tgcaatctta ttagatacaa atacgctgaa atacgaaatg
   112621 gttccagtga aactagatgg ttatgcaatc gtcatcatga atacgaataa gcggcgggaa
   112681 ttggcagatt caaaatacaa tgaacgccgt agcgaatgcg aagaagcctt ggcacgtttg
   112741 caaaaaactt tgcctatctc ttctttagga gacttagatg aagaagaatt tgaatcaact
   112801 attgaccaaa tcggcgatga tacattgata cgcagagctc gccatgccgt ttctgaaaat
   112861 cagcggactt tgaaggcaaa agctgaatta gaagctggga acttagaagc atttggtcaa
   112921 ctgttaaatg attctcacca ctctcttcgc tatgattatg aagtaactgg gatcgaatta
   112981 gatacactag tagatgctgc tcaaaaacaa gaaggtgtct taggtgcacg aatgacagga
   113041 gctggatttg gtggctgtgc gattgctctt gtcaaagaag aaaatatacc tgccttcaaa
   113101 aacaatgtct atgatgaata catgaaagtt gtcggctatg ctccggaatt ttatgttgca
   113161 cacattggaa atgggacaac aaagatcgat ccagaagctg ttcatgtttg ataaaaaaat
   113221 caacgatctc agctaaaaac aaatagataa aaataacctc tcagcaattt ccaaatgtga
   113281 gccttttgct cgtatttgaa aattgctgtt ttttattgac acggaaagag aacgtgtgtt
   113341 ctaattgtgt tgaagaggtg attgttatgt gggcgaatca aaatccggta tttgtttatg
   113401 aaaaagaacc ttcaagagat attttatgta ttgactgcaa atctttttac gcctccgtag
   113461 agtgcgttga aaaggatctt gatcccctta caactaaatt agtagtcatg tcctatccgt
   113521 ccgattcgac agaaacacgg ggtagcggat taatcttggc ttccagtcct gcagcaaaaa
   113581 aagcttacgg catcaccaat atcagccgtg ccagagatct tcccttcccc tatccaagtg
   113641 atttatatat tgttgcccca aggatggcct attatatgga aaagaacaga gaaatcaatt
   113701 ctatctataa aaaatatgca gacgaagcga accatcatgt ctattccgtc gatgaaagct
   113761 tccttgatgt aacaaatagc atggcactct ttggtaaaac aaatgcgtac gacatggcta
   113821 aactgatcca taaagatgtg tttgagcaga ccggaatcta cacgactata ggaattggcg
   113881 ataacccgct acttgctaaa ctagccttag acaatggctc aaaagacgga aagcaaatgt
   113941 ttgctgaatg gcgttatgaa gatgtaccag aaaagttatg gaaaatctca gatatcactg
   114001 acttttgggg aatcggcaaa cgaacagcaa aacgtctgaa acaaatgggt atacattctg
   114061 tttatgattt agctcacgcg gattattatc acttgaaaag caagctaggg gtcatcggta
   114121 ctcagcttta tgcccatgct tggggcatcg atcgaagttt tttgggacaa gaatatacac
   114181 caaaatcaaa aagtatcgga aatagtcaaa tcctagatag agattataca agacgagaag
   114241 aaatcgagat cgttatcaaa gaaatggccg accaagtcgg cactcgcttg agacgatctg
   114301 cagcaaaaac acaagtagtc agcttatggg taggatactc tttaggctat cttgatccaa
   114361 atggcaagac cgggtttcac cagcaaatga aaatcgaagc gacaaatgct agcagagatc
   114421 ttgcagatgc tttattgacc attttccacc agcattacca ctaccaggat attcggcgtg
   114481 taggcgtgaa ctgttccgac ctcgtatacg cgacaggttt acagcttaac ctttttgaag
   114541 atcctgaaaa gcagataaat gaagcgaaag ttgattttgt tgtcgatacg attagaaaaa
   114601 aatacggctt tcaatcaatc atccatgcgc atagtctctt gcaaggagga cgcgccatcg
   114661 cacgtagttc tctcgttggc gggcatgcag gtggtatgag tggattagaa ggtggaaaag
   114721 atgagacgga cagcaaaaaa attcattgac tataacgagt atcgagatcg gccatttgga
   114781 ttaaaatggg ggactgcttt tgcgatggaa gaactagtca acggtatcaa aaaaatgaag
   114841 aagaagcacg caaacagcct cttcctaaac aacaaatgac attgcaagaa atcgatagta
   114901 tactgacaga agccttttta tctcgtaaag cagtaatcat tcagctcaat ttaaaagatg
   114961 aatttggaag actcttggat gaggtcgaag ggcacttcat tggtgaagcc tatgaagatt
   115021 actttatgat tgaccatcag ccgatattgt gggaagacgt acggtatatt gagttaaagg
   115081 aaacaaaaaa atggtttgtg acatgagagg ttgtgacaga agtgatcaac ttcaaaaaat
   115141 aagaaaggat ttttcgaaaa ttgcttctta aatttttgtg gaattttggc ttatttttcg
   115201 aagaagcaac ttctggaaca acgtatatta gatatcagag gttgtgaaaa agtcgcttag
   115261 ttttgagtaa caagccaagg cgctgatttc acaacctctg tctatctatc catctattcg
   115321 gtaagattca tgcatgacgt cttctttatt tagtatgtag agcccttttt cttctgacca
   115381 ttcaacataa atcagctgtt ttacatctgc atagccttct ttcttcaagt tctccataag
   115441 ccatgcttca gtcaattgat tggactgaag cactttatgc tgaatttgcc cttcatctac
   115501 aagcaggatc gataaagctt tgtcttcatc tgattttttc aatacactca tttgaccggc
   115561 attctctagg ataacatgtt tggcattttc aagaaaaaag cattcttgct gtcttaagat
   115621 tgctcgcaac tgctccatct cgatatggtt atttgtcaac tctgtcatgt tgatgacgcc
   115681 gtctttgatt agaacagatg gctcgccttt gacccaacga ttgacctttt catttttttg
   115741 gacgatacgt tcgataccat aaatcattac tgcccaaagc gcaatggcaa ataggacatg
   115801 ccctacatgg acattgtcat cataggttga ttcttctaag atcccaccta aaacaagcgt
   115861 atagactaaa tcaaacggtg tgatttctga catggatttc ttcccaagca aacgtaccac
   115921 taataataaa ccgatcaacc cgaacaccag tttcattgta attgaaaaaa tcattttttc
   115981 tccccctaac tatctgttaa ttaaattata tatgctttct cacgaacacg catggaatat
   116041 acaaggaaga aatgtatcct tttactaaaa aaaggactgt gacactgtag tgacccccaa
   116101 aagttagact tttttggagt ggagaaatcc actccttttt tttatgctct aaaatgatat
   116161 ttttacacaa ccgttacggt tgttttacga aattggacga gactttgcca gtttaatttc
   116221 tgttttatcc gttcattatt gtagtaatag atatagctat cgatggctga ttttaattcc
   116281 tcgaaacagt tataaacttt cccgtgaaaa atctcttgtt ttaataagcc aaaaaaattc
   116341 tccataagtg aattatctaa gcagttccct ttccgagaca tgctttgaaa gattttgtac
   116401 tccttcaatt tgtttctata agctttcatt tgatacgccc aaccttgatc tgagtgaaac
   116461 gtacgacgat agggacaatc gttagtggtc tggatagctt cctccaaacc ttccattacc
   116521 gctaatgcat tgggcttttc agagatacga taggataaaa tctcactatt gaacatatcc
   116581 ataaaaggat ctagatacaa tttcttttga cggataatgc ctttggcatc cacttcatgg
   116641 tatttaaatt cagttgtatc cgtcgtgatt ttctgatggc agatactggt gtagaaacga
   116701 cgatggatcc gatttttggc tactgctcca acttttcctc gataagaatt gtagcgacgt
   116761 gatttacgcg tgtatgccgt tacttttatt cctagcttct tgatcaagcg ctgaactttc
   116821 tttttattga tagagaaacc gcggtttctt agttcattgg tcatccgtaa acagccataa
   116881 tccttgtgct tctcccgaat tttaagcatt tccgcttcaa tctcttgatc tggattttta
   116941 cggtccaatc gcctttgcca tccaaataat catgaacgat ctttaattta agttcaaaag
   117001 tatatttaac cataaaaaat accgacctcc aaaagttaga ttttttggtc taacttttgg
   117061 gggtcggtac acaaatcgtg tcacagtccc ttttttgaaa ataaacggtg ttcaaaagct
   117121 tgcatctgcg gtaataagtc cagccaagtt aaaaacataa gaagctgttt ttacttggct
   117181 gttcttatta cttgatgcaa ggcagctttt tcacaacctc ttttcaaata tttcgttttc
   117241 ttattctaca aatggttctt ctcctaacgc ttgttgagcg gctagattca acatgctcca
   117301 ttgtcggtca aagcctggct ggaagaagaa gtcagcttct gctagttctt ctaaagtcag
   117361 tttgttttgg atcgctagtg ccaatacatt tccttgacct gtaacatcat aggtagataa
   117421 tactgctcct cctagcaatt gatgggtcat tggatccgag aataattgga tggacacttt
   117481 tggatttcct tgttcttctg gtacatattt tggtcgtaac gtatcttcat aataagacac
   117541 tcgtacatct actcctgctt ttgctgctgt aaagctattc aatccgcttg ctgcaaaatg
   117601 atagtcaaag acacttaatg cagaggaacc tacgactccg ccgaacggtt tgtttggtac
   117661 ttcttcaaaa agatgtttta ctacataacg tgcttctcta cgtgcaacag tcgctaaagc
   117721 gatcggcatt tttttgcgtg ctgggataga ataagcaagt gtagcatctc ctactgcata
   117781 cacatctgga agattcgttt gcaagtattc atttgtttgg atccagccac gttcatctaa
   117841 gtcgacgatc ccttttaacc attctgtatt tgccttcaca ccggcagctt gaatgactag
   117901 atctgctggg atttcttttt cacttgtttt gattgcctca acttttccgt taccagtaaa
   117961 agcttcgatt tttgcatttg tcaaaacttc aataccgttt tcatttaggt gttgttctaa
   118021 aatatctgtc atctcagcat ctaaataagt gcctaaaggt ctatcgatca catcaagcaa
   118081 tacgacttct ttcccagctt ttcggcttgc ttctgctgct tcgatcccaa tgtaacccgc
   118141 acctacgaca gcgatttttt taatagccgg atcatttaat ttttctttga ttttggttgc
   118201 ccaattgtat ccacgcatca agtagacatt ttctagatct gctcctggta ctggcagatt
   118261 gtttggtttg acaccagaac tcaaaatcaa tttgtcataa ggatattctt ttgtttcgtt
   118321 atctgatgcg ctagtaaccg ttactgtttt tttatcggca tcgatcgttt ttacttcgtg
   118381 attatttaaa atatgaacat tggattgcgg aaagttttct ggtctgaaat tacgtacatc
   118441 atttacatct gttaccttgt cttctaaata cagctccata ccacatgaca tgaaggaaat
   118501 atagtctcct gcttcaaata gcgtgatatc tacattttca ccgtatcgtg tcaatagttc
   118561 caagatcgat tgatgccctc catgagatgc acctacaatg acaactttga ttttttccat
   118621 tgatgaaacc tccttgaata ttcttttaaa atcattctaa acaatttaaa cttaacatta
   118681 cattagttat gaatcaaaag aaacgcgttc atttgaacta aatttaaaaa acaatcgtct
   118741 ccttgcagaa tataccgcaa aattaacgat tgtttttttg ataaaatcta tgaatcactg
   118801 ttctgttaaa aagtctttga tccgtttgca ggcctcatgt aatttttcca tgctgctagc
   118861 ataagaaatc cggatataac cttctccttc tgggccaaat gcaattcctg ggatacacgc
   118921 aacttttgcc tgttccgcta attctacaca aaactgccaa gagtcagttt gaatggcagc
   118981 tgggagtttg caaaacaagt aaaatgcacc gtttggctgg gtcacttcaa atcctaaagg
   119041 cgccaattgc tggaccagat agtctcttcg tgtttgatat tgctctttca tattctcgct
   119101 atctttcacc ccatttatta gcgcttcagc cgcagctttt tgcgacatcg ttgtagcggc
   119161 agtcaccaga tattgatgga ctttaattag ttcgtcaata agggcttttt gagcaaaaat
   119221 aaagcccact cgccaaccag tcatcgcatg tgacttggat aacccgctta tcacgattgt
   119281 ttgttctgga agataagtag ctatggacat atgcgttcca ctataagtca attcagcata
   119341 tacttcatca cttataacaa ataccggata tttttttaaa acctcagcga ttgctttcaa
   119401 ttgttttgca gacaatgtcg tcccagtagg attgttagga tagtttaaaa tgactgcttt
   119461 gacagctgat ccatattgtt caaatgctcg ttcaaattgt tccggctgac agacaaaccc
   119521 tgtgtcagaa gtatctatcg ggatcaattc agcaccagct agttccacta atggctgata
   119581 tcctgaataa gcaggcgctg gaataagaac cttgtctcct tcttccaaaa cagataacaa
   119641 cgcagaggca atcgcttccg ttgcaccaac tgtcgtcaaa acttccgttt gcggatcata
   119701 agttaatcca taacgctgtt gctgaaatat acaagccgct tcccgcagtt cctctaatcc
   119761 tctcattccg gtatagtgag aaaagtcttc ttcaatcgct gctattcctg cttgcttgac
   119821 atgttcagga gttggaaaat ccggttctcc cagggtgagt ttgatcacat ctggtatcga
   119881 cgatatttgc tgatcgaatt gtcgtatttt tgatacttct attctagaaa gcctaggact
   119941 aaatcgattg gataaattca tcattattta ctcgctcctc ttttgaactg ctatcgattt
   120001 ttacaagaag attttctgta aaaagaatcg ttttgtacca ttctacacca ttttctaaaa
   120061 catccatatc aaaatcgaac gtcggatcat gtaaagcagg ggtatcaccg acacctaaaa
   120121 agaaaaatac acatggatat tgttgcgtat atatgccaaa atcttcggct tgaagaactg
   120181 gagcatctaa ttcatgtagt ttgtttgaat ctaacagtgc tgcatataag cctctatggt
   120241 tgattacagc tggatagccg tcattatagc gaaaagaaat agtagctgta gagtgaaact
   120301 gttctgctaa atggtctaat cccctcttca aataattttg catatctgaa ctgtaagaac
   120361 ggatacttcc ggatacaata acttctccag ctaaaacatt tcggatcgtt ccaccttgga
   120421 tttggccaaa tttcattaga tgattccact ctgccggtaa ttgccggtca aaatcataaa
   120481 cattcttcaa aaatcgtaca gctgcctcca gactatcgat tcctttttca ctagaagcaa
   120541 tatgtgcaga ctggccttta atgataatgt ctgtttcact gctttgtgcc atcaaaggtc
   120601 ctggtcgaga gaaaacttct cccttagcta gtccaggcca tagatgaaag ccaaatattg
   120661 cttgtacttc atatttatcc aacaatcctg actgaataac gctttgtgcg ccaccggaaa
   120721 tttcttctga tggctgatag atcagtacta cattataaat aagatcctca atgtgtttag
   120781 ttataaagtc agtcaaccct aaaagcatcg ccatatgtcc gtcatgacca catgcatgca
   120841 tataaccttc atgcttagaa gcaaaagaga gattcgtttc ttctttgact ggcagtgcat
   120901 cgatatctgt tcgaaaagca atcgtttctt cttgctgatt atcaaaataa aggagtagtc
   120961 ctgtttcgcc gatttcatgg ataacggcct cgctgttttt tacttgttca tataaatatt
   121021 tttttgtctt gaattcatga aacccgattt caggaatttg atggagtgcc attcgatatt
   121081 ctttcagcat ccgtattcac catcccttca tagataccct tcactactgt ttcatattga
   121141 ttattcggta caccgatgat cagattcaac tcctgtgctc cttgtgataa gatcgatgtg
   121201 cgaatttcta atttgttcaa tatcgataac actttcccag ataatccaat caattcttta
   121261 tgcggacccc caacgacaga gatcaaagct aagtcttcga tcacgacgat ttcttccacg
   121321 ccaagtgttt cttttaattc tttcgtgatg agaaataact tatcggcaat cgcttctgct
   121381 gagacgatca ctccgatatt gtcgatccct gaaggaatat gttcgattga tatctcatgt
   121441 ttagcaaaaa tgctcattgc tttccagata aacccgattt catcggacat atgacgtttg
   121501 aataaagtga tggaaagaaa atccttgcgt ccagctattc ctgtcagtcc attttccttt
   121561 tctatttcgt gattcgatat ttttgtccct tgagcgaaag gatcattggt attttttatt
   121621 tggatgggga tatcagcctc ttgaactggg aaaacagctg cttcatgaag aacgttagcc
   121681 cccatataag ccatctctct cagttctcta aaagagattt cctcgatgat tttaggatga
   121741 tcgatgattc gcggatcagc catcatgatt cctgaaacat ccgtccaatt ctcataactt
   121801 tccgcttgca acatcttcgc cagtatcgcg ccggtaatgt cgcttccccc acggcccaat
   121861 aatttttctt ttcctgcagg gttcgccccg taaaaccctg gaacaaccat tttcggatat
   121921 cttttaaatg cttttgtgat ttcctgtgct gttttttcct gatcgatttt cccatcatag
   121981 tcaaagaaaa tcaggtcttt tgcgtcaata aactggtaac caagatactc agccatcagt
   122041 tgagcagtca gatattcacc tctacttact aaataatctt cagttatctt ttcgtcttcc
   122101 agttgtttct gtatgcgtgc tagttcatct tcaataggta actgcagggc aagaacatct
   122161 cttacttgaa tgaaacgatc acaaatcctt ttccaaaggg gtgtccaatc aacatgatgc
   122221 tgaaggtaag cataaatcaa ataaagtaag tctgttactt tgtcatcatc tgacgtacgt
   122281 ttgcctaaag cagaaacaac gatcacttgg cgattgggat ctgaaagaac aattgtacgg
   122341 acttttttga attgctcttc atgagacatc gatgttccgc cgaatttcgc tactttcagc
   122401 gtattactca tcttgccacc tccgctattt tctgcattaa agctgcagca atctgtacgg
   122461 cattcgcagc ggctcctttg cgtatgttat cggcagtcgt atagaacaac aatccgttct
   122521 ctaaagaagt gtcttttctg atcctcccaa cataaaccat atctgttcct ctagcaagaa
   122581 tgctcgtcgg atatttatgt gctgctagat catcttctaa ttgaatccct ggaaactggc
   122641 tgagacactc tctaatttct tccgtcgtaa actctttttg cagttgaact gccacagaga
   122701 ctccatgtcc attttcgatt ggcacacgta cgcaggttgc tgatactggc aaagcaggct
   122761 gatgcagaat cttacgggtc tcatttatca ttttctgttc ttcttttgta tacccatttt
   122821 ccaaaggctg atcgatttcc ggaatcaccg tttggctaat attataagga tacaaaactg
   122881 gttcctcgtc attttgcgta cgatgaagat cttcaatgcc tttttgcccg gaaccagaaa
   122941 ctgcttgata ggtcgaataa ttgactcgct ggataccaaa ggcttcttgt aaagctttaa
   123001 gcggaagtac cgcttgaatg gttgaacaat ttggatttgc aatcagccga ttcaatgtat
   123061 agtcttccag attgacctct ggaacgatta atggaatatc cgaatcttcc cgccatgctg
   123121 aggaattatc tatgacaaat agtccctgac ttcgtgcgat tggcgcaaac tctttggata
   123181 cagaagcacc tgcagaaaat agcgctaaat catatccttc aaatgaagtt tctgtcaatt
   123241 cctgtacagt gtgtttcttt ttcttgaata cacaaacttt accggctgaa cgttttgaag
   123301 ctaataattt caatcgtcct actggaaaat catattcttc taacactttg agcatcgttt
   123361 ggccgactaa tccggttgcc cccacaatac aggtatctat ttcgcgcatt tttctccatc
   123421 tcctctataa ttcgcgtaac gcagcaatca atgctgtatt ttcttttgtc tgatcatcac
   123481 ttatttttaa tacacgtgca ggtattccac cgacaacagt ttctgctgcc acatcttcta
   123541 aaaccactgc tcctgctgcc acgactgcat cttttccgat atggacacct tcaacaatca
   123601 ctgcattcgc acctaccagt acgccgtctt ctacgataac cggtttggcc gatgctggtt
   123661 cgatcacacc tgctaagaca gctcctgcac caatatggca gtttttgccc actgtcgctc
   123721 gtccacctaa gacagcaccc atatcaatca tcgtgttttc accgattact gcaccaatat
   123781 tgataatcgc tcccatcatg atcacggcat tgttgccgat tgacacttga tctctgataa
   123841 tagcacctgg ttcgatacga gcattaattt ttttaatatc tagcaaagga actgcgctgt
   123901 atcttgcagc agtttcgatt tcgatttcaa tgattttttc tgattcagct tctaaaaccg
   123961 gagcaatcgt ctcatagtca ccaaaaacaa cgaagctgct tccttcacca aaaactttac
   124021 tttctttaaa ttcgattggc tcggttacat tcagatagac tttcacaggc gtctttttag
   124081 atgccgtttg aatgtagcgg atgatttctt gagcttccac gttttttaca cccctttgtc
   124141 cattaataaa tcttctaatt tgtaataacc tggtgactga tctttcaacc agtccgctgc
   124201 ttctactgcg cctgcagcaa agattcgatt agaaaaagat tcatgtttga tcgtaaatat
   124261 ttcatcagta gcagcaaaca atacatcatg ttcaccaggt aaagaacctg cacgaatact
   124321 gtgtacacca atttggtttt cttctctttt tttcccttgc cagttgtata cgggctgcag
   124381 cttttgcact tcttggattg tttgaagcag catatttgca gtaccagatg gtgcatcttt
   124441 tttacgacta tgatgttttt caatcagttc gatctgccag ccttgcaaca ttgcagctgc
   124501 ttgcttgatt agttgattca tcaccatgat gccgaacgaa aaattagcac tatacatcac
   124561 aggtacatgt ttggcatgtt cttttatttc ttggaactgt gattgtgtat aacctgtcgt
   124621 gccaatgact aacggaagtt gatatgataa gctatacgaa aggattttct ctaaattatc
   124681 tggatgagaa aaatcaataa gcagttctgg cagttccgta aaagcaagcg tagttgcttc
   124741 tttaggtgcc gtccgtaaaa gaaggaccgt atctcctctt tcttgtgcaa cttcttcgac
   124801 tctatttccc atctgtccac tgccaatcag tccgattttc atttttcaac cgtcctttct
   124861 tttaacaaaa gctgagctaa ttgtttcttt ttctcttttg aaagagaaac taaaggcagg
   124921 cgtagaggtc cggaaggtaa gtctaataat gacatggctg ctttgacagg aataggattg
   124981 gtctcactga acaaggcatg gatcagttca agtgcattta attgcttttc ttttgcttgc
   125041 tgccatcttc cgtcctgcgt atcttttact aattcatgga ctattttagg ttggatattc
   125101 gcccatacac ttattacacc gcttcctcct acactcatta ctggtaggat caaatcatca
   125161 tttccactgt aaaggaagaa ttcttctcca atcaaccgag cggcatccat cacataagcc
   125221 atatctcctg aggcttcttt caaaccaatg atattaggat gttctgctaa atttactaat
   125281 acatggattg gaatcgacat gcctgttcta gaaggaacat tatacaaaat aagcggaatc
   125341 ggtgaggctt ctgcaattgc tgtaaaatga gcagctagtc ctgcatcact tgttttgttg
   125401 tagtaagggg tgatgaccaa aagtgcgtct gcccccaaag aagcaaaatg cttcgctttt
   125461 tcaatcgttt ctttcgtatt attcgttcca gctcctgcaa tcaccggcac acggccagcc
   125521 actttcttta ctgtcagttg aaggatctgc tcctcctcag attgtgtgag cgtagaagat
   125581 tctcctgttg tacctaaaac taataatcca tctgtttgtt catctaaatg gaattggatc
   125641 aatttttcca aaccagcata atctactgat ccctcttcat tcatcggcgt gatcagcgcc
   125701 acgatcgaac cttttatcat cttcattcct ccaatattct tgtccattca tgaactgctg
   125761 ggccagccat ttgtatcgca tcctcaccag agatcatcaa gtctccttgt tccaagtgaa
   125821 caactacctg atctgctgaa attttcccag tttccttagc aaccacataa gaggcacagc
   125881 aacctgtacc gcaagcaagt gtccaaccta ctcctctttc ataggtacgg acgatcaatt
   125941 cttgttcatt gactacttct acaaagttga cattggtttt ttctttgaac aaaggatgat
   126001 gacagatcag ttcacctctt tttctccaga cttcctcacg cgcattttca acaaaaacaa
   126061 cggtatgaat cgttcctaaa aataaactag tgatcgttac tttttcacca ttgatctcta
   126121 tttcctggtt ttttattgga taagtttgat tagctttgat tttttccgga gaatcatctg
   126181 gcactcccat atctacgctg caataaaaag gtgagggatc caacaccgta atttttcttg
   126241 tgcctgctaa tgtctctacg ttgaattcct gttcattcat catgttctga tcatttacgt
   126301 atcgagcaaa acagcgaatg ccatttccgc acatcggcgc gcggctgcca tctttgttgt
   126361 aatagatcat ttccaacgga tcgattttta cggcgatcaa tccgtctata tcatattttt
   126421 cttttgtgca taaagaagcg gctaattgac tataatctgt gtcttctgcg taatctaata
   126481 agataaaatc atttccgcag ccattatatt tatgaaggat cataggaaac ttcccccctt
   126541 agtagatcag aaaatgcttg tctgcgaaca atcagtcttg attggccatt attgacaaaa
   126601 acaactgctg gtcgtgtcgc tcgattgtag ttgctgctca tcgagtatcc ataagctccc
   126661 gtggaataaa cagctaaaag atcacccgat tctgctttcg gcaaataagc ttctttaatt
   126721 accacatcgc ctgattcaca catttttcct gcaatcgtca ctttctctgt tttttcttcc
   126781 gacagttttg ctgctaaatc acaatcgtat tctgcctgat acagagctgg acggatatta
   126841 tctgtcatcc cgccatctac aaagtaatat tttttatgtg gtgtcttttt gatgaaacca
   126901 atcgtgtata gtgttgtacc agcttctcca acaatacttc tacccggttc gatcagtaat
   126961 tgacgaatgg tcagttttcg tttttccaaa gcttcttccg tatattcaat cagttttttt
   127021 agtgcctctt cgactgggat cggctgatca ttttgtgtat aacgaatccc aaaccctccg
   127081 ccaagattca aggaaagagg ttggtcaaaa tcggttaagt aattcgtcaa tttgtcgatt
   127141 tcagctaacc aagcagtaac atcaaaaatt tgtgacccga tatgagcatg aaatccttct
   127201 aactctagat agctgctttc ttttatcaac tgaagggctt gttggcactc tttactttca
   127261 tagctcatgc cgaattttga atcaatatgc gcagtgacga tatattcatg agtatgtgct
   127321 tctactccga cattcaaccg aagcatgata cagatttttt ttaaatagcg ttggcttaat
   127381 tctgctaata attcaacttc catcaaatta tcggcaacaa tatgcaacaa atcattttca
   127441 agtgcataga tcagttcctc tggcgtcttg ttgttaccat ggaagtagat agtatctcta
   127501 ggaaaatcag cttgcaaagc ggtatagatt tccccaccac tgacaacatc tagcccgaat
   127561 ccatattcac gaactaaatg cagcatctca atcgtttgga atgctttaga ggcgtaaagc
   127621 acttttgtat caaaacgttt cgatacaaag cctcgcttga atgacagcat cgtttgtctc
   127681 atcttttctt catcatacac atacagaggt gtcttatact tttctgccaa tgtgcttgct
   127741 gtgactccgc caattatcaa ttctgtcatt ttttcattcc tcttttcact ttttttccgt
   127801 ttttattgga atttcatttg ataaagattt gaattttatt ggaataatat taaacaaaat
   127861 tttctgaatt gtctagtata tttcgaaata tttttttaaa aataagaata aaaatggtta
   127921 taaaaacaaa atacccgaac tattagaagc tatttataca taaaaacata aattcaacac
   127981 tatttagtga tgaaaaaata ttttcgcttc aatatagttc ggaatagttc ggatattttc
   128041 aattttatga atcatttcaa tttcttcata aataagtgca gttttttctt tctctagctt
   128101 ttgccattca tctttcaaaa tataaataaa atcaaatact tttttatttt tcaatttgct
   128161 gattccacaa aaaacctctt gaaaggcaga tccgatgatc tgcctttcaa gaggtcaagc
   128221 tctgttttca aattcttatc aatccgttag cgaattattt tgacgcacgt tttacataag
   128281 aaccttctgc tgtattgatt tccaacaatt catctgtttc gatgaagtca ggaacattga
   128341 ctactaagcc agtttccatt gtcgctggct tacctgaacc agtgactgtt gcacctttga
   128401 tggaaggttg tgtttccaca acacgtaata cgacagttgt tggtaattga acgccgatga
   128461 cttcgctacc gaaaaattgg atttttactt ccatgttttc taggatatat ttcatttctt
   128521 cttctactgt ttctacagga atttcatatt gctcatatgt ttccaaatcc atgaagaaag
   128581 ctgtatcatc catcgtgtac aaatattgta caggttttgt gtcgatatgt gctttttcaa
   128641 atttttcttc tggtctgaac gttgtgtcgt atgttgcacc tgaacggaca tctttcagtt
   128701 tcatacgcat aactgtattt cctttaccag gtttatggtg gcttgcatcc agaactttaa
   128761 tcagtttgcc gtcttgtacg aaagtcatac cggctcttaa atcacttgct gagatcatta
   128821 tttttgctcc ttcttttctt tatcataatc aactttattg tatcagacaa ccggccagaa
   128881 aactagagta ttctctatct tttaaggtct catgcctatt tgtcagaaaa ataaacacgg
   128941 gtaaacgatg ctatcgaaat atttttttct ttcaagcctt tgacttttat tttttttcat
   129001 gctatcgtta ataaaaattt tacttggagg gatacacatg acagtcagca accaaaaaca
   129061 attgaatcgt tgctgttgta tggtgcataa aagcagcata ctatttgtca tgtctattaa
   129121 ttgcccttca tagaatgagt accaggtaac ttatcttttt atctactcaa tttttctcta
   129181 tgtctttcaa ggagctgatt taatagtcag ctcctttttt tattatcttt ttttaggagg
   129241 cccacatgat tatctcgaca attacagaag ctattggttc cacaccgctt tatcgctttg
   129301 acaatcagca ctattctatg cctaaaggtt ctgctattta tgcaaaacta gaatatttaa
   129361 atcctggagg aagtatcaaa gatagattgg gcagttattt gatcaaagaa ggatttgccc
   129421 aaggaaaaat caatgaaaaa acgacgatca tcgaaccaac tgccggaaat acaggaattg
   129481 ggatcgctct ggccgcactc acatacaaat taagaacggt ttttgttgtt ccagagaagt
   129541 ttagcttaga aaaacaacaa ttgatgaaag cattgggagc aaagatcatc cattctccta
   129601 gtgagcaagg aatcatcggt gccatcagca aaagtaaaaa acttgcagag gagatatcaa
   129661 acagctatct gcctcttcaa tttgaaaata aagataatcc tgctgcttac tatcatacgt
   129721 tagggccaga aatctttcat gaaatcaaag aaaatatcca tagttttgta gcaggaattg
   129781 ggagtggtgg aacctttgct ggaacttcta cctttttgaa agaaaaatat cccgacattc
   129841 gaataatcgg tgtagaacca gagggctctg tgttaaatgg tggtgatcca gcccctcacg
   129901 aaattgaggg tatcggtgta gaattcattc cgccgtttct ttctcccctt tcaatcaatc
   129961 agatcgagac aatctctgat gtagaagggt ttaactatac taggcagtta gcacgagaac
   130021 aaggactatt agttggaagt tcgagtggtg cggcttttgc agcagcatta agagaaattc
   130081 gtcgtttacc acctggtcat cgtgtcgtta cgatttttcc agacgcagca gaccgctatt
   130141 tatcaaaaaa catttactta taggaggaaa gaaacatgca cattcaaaca aaattgatcc
   130201 acggaggcat cagtgaagat cccacaacag gagctgtcag tgtacctatt tatcaaacat
   130261 ccacttatcg gcaagatggc gtcggccagc ctaaacaata tgaatattca agatctggta
   130321 atcctactcg ttttgcattg gaagaactga ttgctgattt ggaaggcggt gttcgaggat
   130381 tcgctttttc ttctggtctt tctgggattc atgccgtttt ttctcttttt caagctggcg
   130441 atcatatctt attaggagat gatgtctatg gaggaacatt ccgtctattt gacaaagttc
   130501 ttactaaaaa tggtctcgag tacacgatca tagatacgag taatcttgat aaaatagaac
   130561 aatccatcaa acccaataca aaagcacttt atcttgaaac acctagcaat ccgcttctaa
   130621 agattactga tttagaaaaa agtgccactc tggctcatca acatggattg atagttattg
   130681 ctgacaatac atttgctact ccttattttc aaagaccttt agatctcggt tctgatatcg
   130741 ttgtccatag cggtaccaaa tatctaggcg gacacagcga tgtagtagct ggtttagtga
   130801 cttctaacca taaagatcta gccgatcaga tcggatttta ccaaaatgct atcggagccg
   130861 tacttggtcc ccaagatagc tggttacttc agcgcggaat caagacacta agtgttcgta
   130921 tggaggaaca tcaaaaaaat gcttttgtgg tagctgattt tctattttct catccagcag
   130981 tagaaaaggt ctactatcca ggattacccg atcatgaact ccatggagtt gctaagcagc
   131041 agatgagcgg ctttagcgga atgatttctt ttactttaaa aaatgaagaa tctgctattc
   131101 catttgttga atcactccaa ctatttactt tagcagaaag tttaggtggc gtagaaagtt
   131161 tagtggaaat tccttctgtc atgactcatg cgtctattcc aaaagaaaaa cgagaagagg
   131221 ctggcataaa ggacggcttg atccgtcttt ctgtaggaat tgagtatggt caggatctca
   131281 taaacgattt agctcaggca tttgacagaa tcaagaacta gaagtcccaa taaacgactt
   131341 agcagaaaaa tctaaaaaat atttcagatt gctacacctt ggaaacgata agtgttagaa
   131401 tcaagtagaa agacgttttt gtaaatttca ctaaataatt ctttagtgaa aagcatcaaa
   131461 acgaatgaac aaacagatag gagtcttaca aatgagaatg aatgtcgaaa gttttaatct
   131521 tgaccataca aaagtcaaag caccttatgt acgtgtagct gatcgaaaaa cgggtgcgca
   131581 tggcgatgtc atcattaaat acgacgtccg ctttaaacaa ccaaataaag aacacatgga
   131641 catgccaagt ctacattcac ttgagcactt gactgccgaa ctaatccgca atcacgcaga
   131701 ttacatcgta gactggtctc caatgggatg ccaaacaggc ttttacttga ctgtattgaa
   131761 tcatgaaagc tacgaagaca ttttagatgt tcttgaagca acaatgaaag atgttcttga
   131821 agctactgaa gtacctgcaa gcaatgaaac acaatgtggc tgggctgcca gccatacact
   131881 agaaggtgca caagctttgg ctcgtgaatt tttagcaaaa cgcgatgaat ggtctgaagt
   131941 agaagcatag tttctaaaag aacgtaaaga tgagaagcaa tatagctatc ttatcttcgt
   132001 attttattaa atatttattg tctgaaaaga gttctaaacg ggaaaacaaa tagctagttt
   132061 tcagtttagc gctcttttta ttatataaaa tagaaaggag aaaactttat gtctatttat
   132121 aattttgaaa ctactttaga agacggcact gtctattcat tgaaaaaata tgcaggcaaa
   132181 ccgataatca ttgttaacac tgcaacaaaa tgcggtctag cacctcaatt taaacaatta
   132241 gaagaacttt accaagctta tcagacacaa ggtctggtta tcttaggctt tccttccaat
   132301 caatttaaac aagagctaga ttcagcgact gaagcagcag aagcttgtaa aaccacttat
   132361 ggcgttacct tccctatgca tcaattgatt gacgtaaatg gagaaaatac agatcctctt
   132421 tttacttatc ttaaaaatga agctcctggt actgtcacta aagcaataaa atggaatttt
   132481 actaaatttt tgattgatag aaatggcaaa gtaatcgaac gatttgcacc acaaacttct
   132541 ccattgaaaa tgaccgctgc aattgaatcc gttctttaac ttaataaaaa taaaaaaaga
   132601 tgaactattt ctagttc
//
LOCUS       DAYYEF010000002       117062 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000002 DAYYEF010000000
VERSION     DAYYEF010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 117062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 117062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..117062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.002"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..305
                     /locus_tag="ACHA1B_000129"
     CDS             6..305
                     /locus_tag="ACHA1B_000129"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM8700929.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ACHA1B_000130"
     CDS             378..1739
                     /locus_tag="ACHA1B_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HFM8700930.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ACHA1B_000131"
     CDS             1761..2021
                     /locus_tag="ACHA1B_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700931.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ACHA1B_000132"
     CDS             2035..2787
                     /locus_tag="ACHA1B_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HFM8700932.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ACHA1B_000133"
     CDS             complement(2881..3486)
                     /locus_tag="ACHA1B_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM8700933.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ACHA1B_000134"
     CDS             complement(3539..4513)
                     /locus_tag="ACHA1B_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HFM8700934.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ACHA1B_000135"
     CDS             complement(4891..5610)
                     /locus_tag="ACHA1B_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM8700935.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACHA1B_000136"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ACHA1B_000136"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0019191 - cellobiose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFM8700936.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ACHA1B_000137"
     CDS             7161..8558
                     /locus_tag="ACHA1B_000137"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFM8700937.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ACHA1B_000138"
     CDS             8639..9079
                     /locus_tag="ACHA1B_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFM8700938.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ACHA1B_000139"
     CDS             9227..9553
                     /locus_tag="ACHA1B_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFM8700939.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ACHA1B_000140"
     CDS             9554..10303
                     /locus_tag="ACHA1B_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease prefix domain 1-containing protein"
                     /protein_id="HFM8700940.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ACHA1B_000141"
     CDS             complement(10383..10838)
                     /locus_tag="ACHA1B_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFM8700941.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="ACHA1B_000142"
     CDS             complement(11265..11540)
                     /locus_tag="ACHA1B_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700942.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="ACHA1B_000143"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="ACHA1B_000143"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HFM8700943.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACHA1B_000144"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="ACHA1B_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFM8700944.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="ACHA1B_000145"
     CDS             14770..17436
                     /locus_tag="ACHA1B_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFM8700945.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="ACHA1B_000146"
     CDS             17800..18552
                     /locus_tag="ACHA1B_000146"
                     /EC_number="2.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM8700946.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="ACHA1B_000147"
     CDS             complement(18574..19728)
                     /locus_tag="ACHA1B_000147"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HFM8700947.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="ACHA1B_000148"
     CDS             19913..22354
                     /locus_tag="ACHA1B_000148"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0015936 - coenzyme A metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HFM8700948.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22511..23785)
                     /locus_tag="ACHA1B_000149"
     CDS             complement(22511..23785)
                     /locus_tag="ACHA1B_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HFM8700949.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTLEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRDTEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            complement(24193..24897)
                     /locus_tag="ACHA1B_000150"
     CDS             complement(24193..24897)
                     /locus_tag="ACHA1B_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700950.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(25084..25329)
                     /locus_tag="ACHA1B_000151"
     CDS             complement(25084..25329)
                     /locus_tag="ACHA1B_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700951.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(25346..26197)
                     /locus_tag="ACHA1B_000152"
     CDS             complement(25346..26197)
                     /locus_tag="ACHA1B_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFM8700952.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            26363..27367
                     /locus_tag="ACHA1B_000153"
     CDS             26363..27367
                     /locus_tag="ACHA1B_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HFM8700953.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(27608..27964)
                     /locus_tag="ACHA1B_000154"
     CDS             complement(27608..27964)
                     /locus_tag="ACHA1B_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFM8700954.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            28332..29519
                     /gene="tuf"
                     /locus_tag="ACHA1B_000155"
     CDS             28332..29519
                     /gene="tuf"
                     /locus_tag="ACHA1B_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFM8700955.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(29707..32298)
                     /gene="mprF"
                     /locus_tag="ACHA1B_000156"
     CDS             complement(29707..32298)
                     /gene="mprF"
                     /locus_tag="ACHA1B_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFM8700956.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(32324..33085)
                     /locus_tag="ACHA1B_000157"
     CDS             complement(32324..33085)
                     /locus_tag="ACHA1B_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM8700957.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            33252..33884
                     /locus_tag="ACHA1B_000158"
                     /pseudo
     CDS             33252..33884
                     /locus_tag="ACHA1B_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
     gene            33943..34803
                     /locus_tag="ACHA1B_000159"
     CDS             33943..34803
                     /locus_tag="ACHA1B_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HFM8700958.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            34988..37303
                     /locus_tag="ACHA1B_000160"
     CDS             34988..37303
                     /locus_tag="ACHA1B_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFM8700959.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            37485..39326
                     /gene="dnaG"
                     /locus_tag="ACHA1B_000161"
     CDS             37485..39326
                     /gene="dnaG"
                     /locus_tag="ACHA1B_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003896 - DNA primase activity [Evidence
                     IEA];
                     GO_process: GO:0006269 - DNA replication, synthesis of
                     primer [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HFM8700960.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            39350..40459
                     /gene="rpoD"
                     /locus_tag="ACHA1B_000162"
     CDS             39350..40459
                     /gene="rpoD"
                     /locus_tag="ACHA1B_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HFM8700961.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            40679..42778
                     /locus_tag="ACHA1B_000163"
     CDS             40679..42778
                     /locus_tag="ACHA1B_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division site-positioning protein MapZ
                     family protein"
                     /protein_id="HFM8700962.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            42974..43837
                     /locus_tag="ACHA1B_000164"
     CDS             42974..43837
                     /locus_tag="ACHA1B_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor B family protein"
                     /protein_id="HFM8700963.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            43942..44415
                     /locus_tag="ACHA1B_000165"
     CDS             43942..44415
                     /locus_tag="ACHA1B_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFM8700964.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            44511..45398
                     /gene="xerD"
                     /locus_tag="ACHA1B_000166"
     CDS             44511..45398
                     /gene="xerD"
                     /locus_tag="ACHA1B_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009009 - site-specific recombinase
                     activity [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HFM8700965.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            45417..45788
                     /locus_tag="ACHA1B_000167"
     CDS             45417..45788
                     /locus_tag="ACHA1B_000167"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8700966.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            45785..46555
                     /locus_tag="ACHA1B_000168"
     CDS             45785..46555
                     /locus_tag="ACHA1B_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HFM8700967.1"
                     /translation="MNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDIPIATITEQY
                     MNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEEDPREELVTQ
                     LLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKKIDLIRAMQK
                     ILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESPSKSEVVTTF
                     MALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            46539..47108
                     /gene="scpB"
                     /locus_tag="ACHA1B_000169"
     CDS             46539..47108
                     /gene="scpB"
                     /locus_tag="ACHA1B_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HFM8700968.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            47114..47830
                     /locus_tag="ACHA1B_000170"
     CDS             47114..47830
                     /locus_tag="ACHA1B_000170"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFM8700969.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     regulatory      47912..48037
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            48160..48771
                     /locus_tag="ACHA1B_000171"
     CDS             48160..48771
                     /locus_tag="ACHA1B_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFM8700970.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     gene            49149..50672
                     /locus_tag="ACHA1B_000172"
     CDS             49149..50672
                     /locus_tag="ACHA1B_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFM8700971.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            50909..52249
                     /locus_tag="ACHA1B_000173"
     CDS             50909..52249
                     /locus_tag="ACHA1B_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFM8700972.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            52402..53139
                     /locus_tag="ACHA1B_000174"
     CDS             52402..53139
                     /locus_tag="ACHA1B_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HFM8700973.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(53304..53525)
                     /locus_tag="ACHA1B_000175"
     CDS             complement(53304..53525)
                     /locus_tag="ACHA1B_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0009055 - electron transfer activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HFM8700974.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            53556..54587
                     /locus_tag="ACHA1B_000176"
     CDS             53556..54587
                     /locus_tag="ACHA1B_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8700975.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            54574..55977
                     /locus_tag="ACHA1B_000177"
     CDS             54574..55977
                     /locus_tag="ACHA1B_000177"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HFM8700976.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            56043..56678
                     /locus_tag="ACHA1B_000178"
     CDS             56043..56678
                     /locus_tag="ACHA1B_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAG1386/EF1546 family surface-associated
                     protein"
                     /protein_id="HFM8700977.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            56727..57407
                     /gene="cmk"
                     /locus_tag="ACHA1B_000179"
     CDS             56727..57407
                     /gene="cmk"
                     /locus_tag="ACHA1B_000179"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004127 - (d)CMP kinase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HFM8700978.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            57542..58771
                     /gene="rpsA"
                     /locus_tag="ACHA1B_000180"
     CDS             57542..58771
                     /gene="rpsA"
                     /locus_tag="ACHA1B_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HFM8700979.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            58953..60263
                     /gene="der"
                     /locus_tag="ACHA1B_000181"
     CDS             58953..60263
                     /gene="der"
                     /locus_tag="ACHA1B_000181"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HFM8700980.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            60506..60781
                     /locus_tag="ACHA1B_000182"
     CDS             60506..60781
                     /locus_tag="ACHA1B_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HFM8700981.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            61016..62062
                     /locus_tag="ACHA1B_000183"
     CDS             61016..62062
                     /locus_tag="ACHA1B_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700982.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            62064..63323
                     /locus_tag="ACHA1B_000184"
     CDS             62064..63323
                     /locus_tag="ACHA1B_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFM8700983.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            63329..63910
                     /locus_tag="ACHA1B_000185"
     CDS             63329..63910
                     /locus_tag="ACHA1B_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ReoY family proteolytic degradation factor"
                     /protein_id="HFM8700984.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(63992..64867)
                     /locus_tag="ACHA1B_000186"
     CDS             complement(63992..64867)
                     /locus_tag="ACHA1B_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFM8700985.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            65015..65347
                     /locus_tag="ACHA1B_000187"
     CDS             65015..65347
                     /locus_tag="ACHA1B_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFM8700986.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            65459..66667
                     /locus_tag="ACHA1B_000188"
     CDS             65459..66667
                     /locus_tag="ACHA1B_000188"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HFM8700987.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            66821..67275
                     /locus_tag="ACHA1B_000189"
                     /pseudo
     CDS             66821..67275
                     /locus_tag="ACHA1B_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            67637..67912
                     /locus_tag="ACHA1B_000190"
     CDS             67637..67912
                     /locus_tag="ACHA1B_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8700988.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            67925..70003
                     /locus_tag="ACHA1B_000191"
     CDS             67925..70003
                     /locus_tag="ACHA1B_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFM8700989.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            70166..72049
                     /locus_tag="ACHA1B_000192"
     CDS             70166..72049
                     /locus_tag="ACHA1B_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFM8700990.1"
                     /translation="MKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKTS
                     LLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVRA
                     YEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIST
                     LSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDRY
                     FLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMRA
                     GVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRINDQ
                     TLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQE
                     NEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEKR
                     RLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVAD
                     KLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKEW
                     ETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSEW
                     VED"
     gene            72061..73008
                     /locus_tag="ACHA1B_000193"
     CDS             72061..73008
                     /locus_tag="ACHA1B_000193"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004799 - thymidylate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HFM8700991.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            73028..73555
                     /locus_tag="ACHA1B_000194"
     CDS             73028..73555
                     /locus_tag="ACHA1B_000194"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFM8700992.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(73618..74271)
                     /locus_tag="ACHA1B_000195"
     CDS             complement(73618..74271)
                     /locus_tag="ACHA1B_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HFM8700993.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            74403..75245
                     /locus_tag="ACHA1B_000196"
     CDS             74403..75245
                     /locus_tag="ACHA1B_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFM8700994.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            75403..76299
                     /locus_tag="ACHA1B_000197"
     CDS             75403..76299
                     /locus_tag="ACHA1B_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFM8700995.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            76302..77015
                     /locus_tag="ACHA1B_000198"
     CDS             76302..77015
                     /locus_tag="ACHA1B_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HFM8700996.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            77035..77553
                     /gene="msrA"
                     /locus_tag="ACHA1B_000199"
     CDS             77035..77553
                     /gene="msrA"
                     /locus_tag="ACHA1B_000199"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFM8700997.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            77550..77777
                     /locus_tag="ACHA1B_000200"
     CDS             77550..77777
                     /locus_tag="ACHA1B_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HFM8700998.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            77929..78480
                     /gene="lepB"
                     /locus_tag="ACHA1B_000201"
     CDS             77929..78480
                     /gene="lepB"
                     /locus_tag="ACHA1B_000201"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFM8700999.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(78563..79105)
                     /locus_tag="ACHA1B_000202"
     CDS             complement(78563..79105)
                     /locus_tag="ACHA1B_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFM8701000.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(79342..79740)
                     /locus_tag="ACHA1B_000203"
     CDS             complement(79342..79740)
                     /locus_tag="ACHA1B_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM8701001.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            80000..80860
                     /gene="ylqF"
                     /locus_tag="ACHA1B_000204"
     CDS             80000..80860
                     /gene="ylqF"
                     /locus_tag="ACHA1B_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HFM8701002.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            80853..81620
                     /locus_tag="ACHA1B_000205"
     CDS             80853..81620
                     /locus_tag="ACHA1B_000205"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HFM8701003.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            81676..82533
                     /gene="dprA"
                     /locus_tag="ACHA1B_000206"
     CDS             81676..82533
                     /gene="dprA"
                     /locus_tag="ACHA1B_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009294 - DNA-mediated transformation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HFM8701004.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            82655..84733
                     /gene="topA"
                     /locus_tag="ACHA1B_000207"
     CDS             82655..84733
                     /gene="topA"
                     /locus_tag="ACHA1B_000207"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HFM8701005.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            84702..86078
                     /gene="trmFO"
                     /locus_tag="ACHA1B_000208"
     CDS             84702..86078
                     /gene="trmFO"
                     /locus_tag="ACHA1B_000208"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0047151 - tRNA
                     (uracil(54)-C5)-methyltransferase activity,
                     5,10-methylenetetrahydrofolate-dependent [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HFM8701006.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            86276..87181
                     /gene="xerC"
                     /locus_tag="ACHA1B_000209"
     CDS             86276..87181
                     /gene="xerC"
                     /locus_tag="ACHA1B_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HFM8701007.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            87218..87766
                     /gene="hslV"
                     /locus_tag="ACHA1B_000210"
     CDS             87218..87766
                     /gene="hslV"
                     /locus_tag="ACHA1B_000210"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0004298 - threonine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HslVU peptidase proteolytic subunit"
                     /protein_id="HFM8701008.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            87780..89180
                     /gene="hslU"
                     /locus_tag="ACHA1B_000211"
     CDS             87780..89180
                     /gene="hslU"
                     /locus_tag="ACHA1B_000211"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009376 - HslUV protease complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HFM8701009.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            89198..89989
                     /gene="codY"
                     /locus_tag="ACHA1B_000212"
     CDS             89198..89989
                     /gene="codY"
                     /locus_tag="ACHA1B_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HFM8701010.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            90071..90946
                     /locus_tag="ACHA1B_000213"
     CDS             90071..90946
                     /locus_tag="ACHA1B_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HFM8701011.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(91078..91716)
                     /gene="plsY"
                     /locus_tag="ACHA1B_000214"
     CDS             complement(91078..91716)
                     /gene="plsY"
                     /locus_tag="ACHA1B_000214"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008374 - O-acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006654 - phosphatidic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HFM8701012.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            91843..92277
                     /locus_tag="ACHA1B_000215"
     CDS             91843..92277
                     /locus_tag="ACHA1B_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0120225 - coenzyme A binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HFM8701013.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            92443..94488
                     /gene="parE"
                     /locus_tag="ACHA1B_000216"
     CDS             92443..94488
                     /gene="parE"
                     /locus_tag="ACHA1B_000216"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HFM8701014.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            94500..96950
                     /gene="parC"
                     /locus_tag="ACHA1B_000217"
     CDS             94500..96950
                     /gene="parC"
                     /locus_tag="ACHA1B_000217"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HFM8701015.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            97227..99458
                     /gene="pflB"
                     /locus_tag="ACHA1B_000218"
     CDS             97227..99458
                     /gene="pflB"
                     /locus_tag="ACHA1B_000218"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HFM8701016.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            99702..100463
                     /gene="pflA"
                     /locus_tag="ACHA1B_000219"
     CDS             99702..100463
                     /gene="pflA"
                     /locus_tag="ACHA1B_000219"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase-activating protein"
                     /protein_id="HFM8701017.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            100548..101474
                     /locus_tag="ACHA1B_000220"
     CDS             100548..101474
                     /locus_tag="ACHA1B_000220"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004427 - inorganic diphosphate
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HFM8701018.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            101656..102549
                     /locus_tag="ACHA1B_000221"
     CDS             101656..102549
                     /locus_tag="ACHA1B_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HFM8701019.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            102683..102808
                     /locus_tag="ACHA1B_000222"
     CDS             102683..102808
                     /locus_tag="ACHA1B_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family protein"
                     /protein_id="HFM8701020.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(102942..103574)
                     /locus_tag="ACHA1B_000223"
     CDS             complement(102942..103574)
                     /locus_tag="ACHA1B_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701021.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(103722..104264)
                     /locus_tag="ACHA1B_000224"
     CDS             complement(103722..104264)
                     /locus_tag="ACHA1B_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HFM8701022.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            104399..104788
                     /locus_tag="ACHA1B_000225"
     CDS             104399..104788
                     /locus_tag="ACHA1B_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701023.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            104792..105556
                     /locus_tag="ACHA1B_000226"
     CDS             104792..105556
                     /locus_tag="ACHA1B_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFM8701024.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            105685..106632
                     /locus_tag="ACHA1B_000227"
     CDS             105685..106632
                     /locus_tag="ACHA1B_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8701025.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            106762..107502
                     /locus_tag="ACHA1B_000228"
     CDS             106762..107502
                     /locus_tag="ACHA1B_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701026.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(107793..108461)
                     /locus_tag="ACHA1B_000229"
     CDS             complement(107793..108461)
                     /locus_tag="ACHA1B_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFM8701027.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            108595..108882
                     /locus_tag="ACHA1B_000230"
     CDS             108595..108882
                     /locus_tag="ACHA1B_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701028.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            109298..110836
                     /locus_tag="ACHA1B_000231"
     CDS             109298..110836
                     /locus_tag="ACHA1B_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HFM8701029.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            110833..111798
                     /locus_tag="ACHA1B_000232"
     CDS             110833..111798
                     /locus_tag="ACHA1B_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701030.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            111785..113107
                     /locus_tag="ACHA1B_000233"
     CDS             111785..113107
                     /locus_tag="ACHA1B_000233"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFM8701031.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      113170..113274
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            113348..114091
                     /locus_tag="ACHA1B_000234"
     CDS             113348..114091
                     /locus_tag="ACHA1B_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8701032.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            114106..115098
                     /locus_tag="ACHA1B_000235"
     CDS             114106..115098
                     /locus_tag="ACHA1B_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8701033.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            115110..115847
                     /locus_tag="ACHA1B_000236"
     CDS             115110..115847
                     /locus_tag="ACHA1B_000236"
                     /EC_number="7.6.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701034.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            115837..116559
                     /locus_tag="ACHA1B_000237"
     CDS             115837..116559
                     /locus_tag="ACHA1B_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFM8701035.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(116643..>117062)
                     /locus_tag="ACHA1B_000238"
     CDS             complement(116643..>117062)
                     /locus_tag="ACHA1B_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFM8701036.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        39397 a        20199 c        24508 g        32958 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaag
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttattgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagctg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttggctct tcgtcaaatt
    22441 gtgttggcga agacaaattt gaataaaact tagtccgata tgcggcgcgt tctgtgcgcc
    22501 gcatattttt ttagttttca aagatcagac cttgttgtaa atagatccgt gcccgaaagt
    22561 tataaaagtt gcgataacca aacgcaattc gtttaatcag cttgatcttg ttattcagcc
    22621 cctcagtgac gccgtttgag tggggcacct taaaggcatt tgaaataccc gattggtagc
    22681 gatggaagat cgtgaatttc tttttaaacg actgaggtaa cgtagatgaa attgttttaa
    22741 gggtttcttg aaagccttcc gtatctcgtt taacgaaata atagcgtaat aattgacaaa
    22801 aatgatacgc agttcgcaat tcttcgttgt agcttaacag ctcatcaacg atttctgttt
    22861 gactaattgg tcgtttaaac agtcgatgat aatgccgttt gagtggctcc aatgtcgtgg
    22921 aatctttgag taagagtttc caatatcgct tgagccgacg gtacttcttc tgattttcag
    22981 agtgtgaggt tcgaaaacga ttcatgatct ggacacgtaa ttgattgaag ctgcgattga
    23041 tgtgttggac aatatgaaag cggtcagtta cgatctccgc atttggaaag actgttttaa
    23101 gcaactgaca atagctggca ttcatgtcca tcactaggta cttgaccttt aaacgggcct
    23161 ttctaggaaa gcgcaggaag tattgagtta gtttgtaaag tctgcgatct tcaaggatcg
    23221 taaatagctg attggttgtc ccatcaacac aaataaaact catggaacca gaaacagact
    23281 tcattgattt gaactcatcc atacacaaca ccgtcggaag gaagttcata cgtggctggt
    23341 aatgcttcgt tgcttcacgc aagatccgtg tcaccgtccc atccgagacg aagtacttct
    23401 tagcgattag tttacgtgat tgattttcgt acagttccat gagaatcgcc tgcttcagtt
    23461 cctttgttag ttgatgatgt tcatcaacta agtccgtttt cgcagaaaag gtccgtccac
    23521 aatcatggca gagaaaacgg gtacgtttta attctaaaat agtcaacttt tctttgactt
    23581 tcaacatctg agtgcgtgtc gtataggaac cgttgcggat aatacgaatc gatccacagt
    23641 gttcacaatg ggaaggtgag tcatccaatc tccctttaat aaactgcgct tgaacgcctt
    23701 tatattcttt ttcaatcagc cattcttcat caaaaaataa atgtttatct gttaatccga
    23761 gtaattttct agtatgatta tccattgaga gactcctttg gtagggtgac gttttggtcg
    23821 actaaatttt accaaaagtg agtctctttt tgagttgaaa cgaagaaaaa agtgttagta
    23881 gaaaatcgct ttcgattttc caccaacaca aaatattata gaaccgcttt tttctctatc
    23941 agaaaatatg tttattatta gaatttttta tagttaaggt taggcatctt aagaaatcag
    24001 gcaactccaa gatatcttca ggtagaagag aagtcgccta acattgtagg atcataggtg
    24061 atttgttgga caggtcaagc tgatatttga gcctgatgtt agaaggaatt tctttttact
    24121 tgctgtagaa attattatat gactaaaaag gctgggattt taaatcccag ccttttatga
    24181 caaatagaat ttttatcgat cagtaatcgc tgtcgctgca aattgttcga tcaaaggaat
    24241 caaagtcaat ttgactttgt atttccgttc gagtgctttt tcgataacga actcattttc
    24301 agtagtcata gaaatagttg ctaatttacg aggttcatca gcattttttt cattaataac
    24361 tacttcatgt tcattttgtt ctgtgtaaaa tttaggatac tcagcaacgg cttttgaaaa
    24421 atcagcaaaa cttaaagcgg cattcgtatc agttgagcgt gtattttcag ttgtgtccgc
    24481 ttttggtttt tccgtttttt cttctggcac actgactgtt tcttctgtaa ctggtgtcgc
    24541 aacagcttgc gcagttggtt catcgttttt caatcgttga tcattccagt aagacacgat
    24601 ttcaataaga agattgtcac ggaatcgttc gaaaatcccg ttttctcctg aacgaattct
    24661 ctttaataca gtattgaagt tgtcatcgat tggcacgttg atccgtgtat cttcatttgt
    24721 tttcccagct aatccgatcg ttaagatttg acggtttttg ggatcaagca tgacttgtaa
    24781 cggcaaacca taacgtcgca agctctcttc ttctagagaa cggaataatt gtcctcttac
    24841 accatccaat gaaggacgga attgatttaa taatttttgt ttctgttttt tcttcatatg
    24901 ttctctcctt cgctcatacc ctttcgatta taagaaaaaa acagccaaat gaaaaggagt
    24961 aatgcaaaaa aacttgcgta tacgcaaatt acaacagaaa aatttgcgta ttttcccgtt
    25021 ttttgaaaga aaaataaaaa atggaacgga ttatgtatat atacataatc cgttccattc
    25081 tttctatttt ttcggtatca aggcaaaaac aggtagttca ggtgaataaa tgacttcatg
    25141 ttcgtgccag ggtttgacca ttagcgaatg atcgaaccgt tttttcagtt cttcgatgat
    25201 ttgatcatgt gtccagtttc ttgcaggaaa atgttggatt ttctctgcat cgatcaaaaa
    25261 gacaaaatcg gaatgaaaag tctgggtaac ttcttccgag agagaattca agcgttcgat
    25321 tggatccata aaatcacctt tcgacttaaa attgggtagt atctgggtct tttgctttgc
    25381 cgactacacc atctaactga tcgatttgtt tcatttcttc ttctgttaat tcaaaatcaa
    25441 ataattcagt attttctttg attctgcttg gtgtcactga cttaggaaga ggaaggaatt
    25501 cgtgttgcag cgaccaacgc aaagcaactt gtgcaatcgt cttgtcatgt gcttcagcga
    25561 tttgtttcat ttcaggcaca tcgaagattt taccagtgcc taatggacta tatgcttcga
    25621 ggatcatatc atgttttttt gcatactcaa ctacagttgt ctgtaattcg cctggtgcaa
    25681 ggaaaacttg attgaccatc ggcataattt ttgctgtttt tgctagtgta tctagatggt
    25741 ggggtaagaa attgctcaca ccgattgctt tgattttacc tgcttcatac agttcttcaa
    25801 atgctcgcca tgtatctgca tttgcttgtt cccaattatc acgaaaagca acagggtttg
    25861 gccagtggat caaaaacaga tctaaataat ctgtttggag cttcttcaat gattcttcaa
    25921 aagaagacat cacaagttca tagctgtggt ttgcattcca taattttgtt gtcaagaata
    25981 tctcttctct aggaattcca ctttccttaa tcgcttggcc gacgctttct tcattcttgt
    26041 atccttgggc agtatcgata tggcgataac ctgcagccag cgcttcttta acagaggaaa
    26101 cagcgacatc cccatcaggt gtttgccatg tgccgaatcc tactaccggg atttcgtaac
    26161 catttgatag acgataagtg cttgttaatg aattcatact ttcagctcct tttttattcg
    26221 ttcaactata agtgtagcgc atttttcgaa aaaaagaatc cattttgttt ctactcttga
    26281 aatttttgtt taaaagaaaa tgattttgat tctggtattt ttgatttttt ttccgtaaac
    26341 taagacagaa gggaatgaga aaatggatat ctatttaaaa aaagcaattc tgcatattat
    26401 tgacagagaa actggttctc cagtcttttc acaaaaagag ctggatctga caaaagaata
    26461 tattcgtgat tttcttcaaa agaagatcca aaaaatctct tctgctcaaa caaaaactgg
    26521 acaactagca gaagaaagca tgatcgttga atcacttaaa atcgctcaag aaaattttgt
    26581 ggaagcaagt gaagcaatcg ttcagcggtg gttcgatatc taccaagaaa gtgaagaagc
    26641 acctagtgca gatgtatttg ttgtcttgta tgaattagat acagtgatgt acttatcttt
    26701 attgaaagtc aattatcgtg aggcttacac tcactttgtt gaagcagacg aagcagggat
    26761 cgacaaccgc ttgattttga atcgagcaat tctaggggcg aaaacacaaa aagcagatga
    26821 agcattcgct gtgaatttga ctgattggac ctacgaatta attgaaaaaa aatatgagtt
    26881 ttctggcaaa aaagagcttt atttttctgg aagagtgatc gaaagtgttc ctgcaccttc
    26941 tttagaagaa aatgtaaaag tgatccaaaa agtagccaag catcttggaa aaaaatttga
    27001 gacagaagaa tttgatatca tggctgattt gaaagaagct gtctatgata cgatagaaga
    27061 aaaaggtcgg ttggatcatg agatgattgc ggaaaaagtc ttcaaggaaa acatcacggc
    27121 aaaaatggct tttaaagaag aagtacaaga gcaaggattt gtcccagaag cacctcctgt
    27181 aaaagaagta caagaaattt ctgagaaaaa atttggaaaa caaaaattca agctatcaaa
    27241 cgggatcgaa ctgatcgtac cagtagatgt atatcgcaac ccagatttga ttgaatttgt
    27301 gaataatccg gatggtacga tatccgtgat gatcaaaaat gtggatgaag tattgaatcg
    27361 tttataaaaa tgactagaat attaggtgtt caagtaccag tgatcagtta aatgaattgt
    27421 gtcaagagaa ggatcggaaa agacgaatat aacaaaaaaa gagcgtgaga caaaagtaaa
    27481 gaacactttt gtctcacgct ctaaacacgt ataaacggcg gaagcagaag caactccttc
    27541 ttatttcttg gagttaaacg cttctgtccc agcctctttt tatctaataa aattttaaga
    27601 ccatttacta attatcgatt ttttctgccg catttttagg cacttcagaa gcctttattt
    27661 cttcccagct taatacacct ttacgaggat tgactttgag tttaagatac gcattcatct
    27721 ttaatggatg ttctctttct tcgcgaagcg tcacctgttt tttttcacca tctttattat
    27781 aagccgcttg cttgtaggta taagtcgtga atttctctcc gttatctgct tgggtagctg
    27841 acatttcgcc attcgtcgtg atttttgtat aataagcttc gccgccgtaa aaataatgat
    27901 aagctgcaaa acttccgccg agaaatatgc ctaaaacgac aagtacgcca attaattttt
    27961 tcatgtactt cacctctttc cttattatta acgaaataga agatttcgtc tattgaaagt
    28021 tgttggcaac agctgaattt taaacttttc ctcattttgt tcttattgct tcaaaagaaa
    28081 gttaaggact atcttgaagt ttttctcaaa aaacacattt ttttatttat aaaaggtact
    28141 tttttcgcgt ataagacaga cgagtgctct tagttgactt tgaccaatat tgacgtataa
    28201 taagcttagt tcgaatctta caaaaagtaa gtcggacgta ttctttttga tttagtcaaa
    28261 aaaagactat aataaaaagg tgagagctga aatttttcag tgatctatat tatttaggag
    28321 gtttgtaaat tatggcaaaa gaacattatg acagaagtaa accacacgtt aacattggta
    28381 cgattggaca cgttgaccat gggaaaacta ctttaactgc tgcgatcact acagtattag
    28441 gcaaaaaagg cctagcaaat cctcaagact atgctagtat tgatgcagct ccagaagaac
    28501 gtgaacgtgg gattacgatc aataccgcac acgtagaata tgaaacagaa aaacgccact
    28561 acgcgcatat tgatgcacca ggacacgcgg actatgtgaa aaacatgatt acaggggcag
    28621 cacaaatgga tggtgcaatc ttagttgttt ctgcaactga cggtccgatg cctcaaacac
    28681 gtgaacacat tttattgtca cgccaagttg gtgtaaaata cctgattgtt ttcttgaaca
    28741 aagttgattt agtcgatgat gaagaattga tcgatttggt agaaatggaa gttcgcgagt
    28801 tattgagcga atatggtttc ccaggcgatg acactcctgt gatcaaaggt tccgcattaa
    28861 aagcattgca aggcgatcca gatgctgaag ctgctattat ggaattgatg gatacagtag
    28921 atgaatatat cccaacacca gaacgtgata cagataaacc attactattg ccagtggaag
    28981 acgtcttctc aattacaggt cgaggaactg ttgcctcagg tcgtattgat cgtggtgctg
    29041 ttcgtgtcgg tgatgaggta gagatcgtag ggatcaaacc tgaaacacaa aaagcagttg
    29101 taacaggtgt agaaatgttc cgtaaaacgt tagattacgg ggaagctggg gataacgtag
    29161 gcgtgttgtt acgggggatc caacgtgacg atatcgaacg tggacaagta cttgctaaac
    29221 caggttccat tactccacat acaaaattca aagcagaagt gtacgtgttg acaaaagaag
    29281 aaggtggacg tcatactcca ttcttcaaca actatcgtcc acagttctac ttccgcacaa
    29341 ctgatgttac aggaacaatc acattgccag aagatacaga aatggtcatg cctggtgaca
    29401 acgtgacgat tgatgttgac ttgatccatc caatcgctgt tgaaaacgga acgacattct
    29461 caattcgtga aggcggacgg acagtaggtt caggtatcgt tacagagatc gaagcataag
    29521 aaacgcgact cgaatatttt ggtaatgaaa aatgtttaaa ataaaagagc ggtccaaaca
    29581 ggatttctgt ttggaccgct ctttgttctt caattgtata agaagagatt gtagaagcat
    29641 gaactttcgt tttacttcag tctcttttat tcatcatgag agtgttcatc tatcggtatg
    29701 cagtttttaa tactttcttc gtatccattt tttcaaacca cttattctac cttgtgtctg
    29761 ctcaactggc gcattatcaa taatcagcaa agcaatcata acatatgcaa tccaactatc
    29821 tctagaatat agagtataac gtgagaccca gtttgtagcg tacttgcttt tatattctct
    29881 taatccatgg aaagaataaa aatgagaacc aaactcgtaa accaagtatg caatcctttc
    29941 ctgtaaaaaa ctctttctgg aagttccgac atttgaaaga ggggccatcc ctaaattgaa
    30001 ccattggata tgttcttctt tcatataggc aaacaaatgc aagaacaaga aatccatact
    30061 gccagaaggt gcttttttag aatcatatcg catcagatca atcgttccta ctttattgtt
    30121 cgtgtaagta ggcatgatcg ttgcaaaagc gacaatttct tcttgggtat ttttgacaac
    30181 tgcaataggc gctctttgta gataatcttc agagaaaaag cctaaagaaa accctttttc
    30241 ctttcgtgaa cccaaccaat tatcagagat atttttgaaa gtactcattt gctcagtaga
    30301 aaatggtggt tgtaagacat caaatgtaaa tccttctcgt tcgatccgat tcaagacagc
    30361 acgagtgccc ttcatttttt tccctgaagt tgtaaaacta ttcaggtcta cataagcttc
    30421 ttcccccatc ttaatgaaat cgtagccgaa ttcatgcaaa atcataacaa tctcttcgct
    30481 tgtttcgtag aaaactggta aatagcatag tcgatctgtt tcttcgataa aagcttcgat
    30541 tgcttctgga aaatcttctt tcttaccaga aggatcaccc attacaatac atttattatt
    30601 gaagcaagcg aattggagaa gaacagttgg ttcaccgtct ttttcatagg caaacatccg
    30661 cttatctttt aagaagatca attgactatc ggagtttcct ccataagttg taaggatctt
    30721 cagggccttt tcttcattaa aggcttcgcc aatctgtttc ttttctcctt gaaggaaatg
    30781 aacaaataga acgatcatga aactaacagc gatgatggcc aacaatcccg aaaaccaaat
    30841 cttttcagaa ggaaataaga aaaaggaaat aaaatggtga cgccgatgag ggaaatccgg
    30901 cagattgtat accccaataa cgatgtaaag caaggacagt gcaccaataa tgattccatc
    30961 gatcgtacgc cactcccatg aatagatcaa ttgttcccga aataattcgt ttttagaagc
    31021 aagaatgatc agaagcagaa tagacaagaa aaccaccggt gtgaaactaa aatcacttaa
    31081 taaaacataa agtaaagcta gaacaatcaa gaagattgta ggcaaatatg ctcgtttcac
    31141 acgtgctgcg atccctctgc ccataatgat taaaagaaat cccaatagta tactaggaaa
    31201 ttggataata aaatgaaatt tcaatgggtt caaactatga agccagcgaa actctgtaaa
    31261 agcttgcggg atagtggcag aaagtactag catgattcca gaaaagtata ataagacaac
    31321 cacgatttta tgcgcaattt ctgttgctaa ttgtttaggg ataccagaat aacgctgatc
    31381 aaaagtggaa ccgatatttt tgaagaaaaa gacgattcca atcaaaaacg gaatgatgta
    31441 gtagaacagg cgatagagca agatccacac aacgactatt tctcttggca caccaatagc
    31501 ggacaacccg ataatcatca ttacatcgaa actcccaatt tctcctggaa tcatagacac
    31561 gattcctatc actgaagcag caatgaataa tggaattgtt tgccacagat caatccggat
    31621 ttccattaaa taaccaacag aaaggaaact aaacaggaca ccggtccatt ccaacaatga
    31681 aactagcaat agctgtcctt gagttttaag tgaggtacca ccaaggaatc ctttcttttt
    31741 gaaagtagta aataaaaaga cgacaggaaa atatagaccg ccgccgatca accatatcca
    31801 atattgcttc aaaaaaggag caactggcgt gaagactaca agtaaaaaag aaagcagact
    31861 gtaaatagaa agtccagcca tcaaaaacaa gaaaactttc gataatgctt ggatcacgtt
    31921 tctgctctct ttcttttgtc catatagttc agagcgaagc cccacactaa caaacccgcc
    31981 gaaaccggca atattgttga tcgtattgat cagccagctt gtctcaaaca ggtaacgagg
    32041 attctgcttt tgttcaagca tccgattcaa aataatatca taaccaacca taggtaacac
    32101 agagataaga ccaatcaata gcattagtcc gcttttccat acaggtatag tggcaaacgt
    32161 ttctcctaat tgctggatag atagagtttt accgatggac atcaattcac cgacaataat
    32221 gacaatgaca gaaatcaaaa agattgtttt gaacagtcct aggtggtttt tcagccattg
    32281 tatggtattt tttaacaaat aaatcacctt ctattcctaa tagttatgtt tcagaaagaa
    32341 attgaagaac ttctcgattg aagcgttcag gatcttttct agctaattca tgtccttgtt
    32401 ctttcacaag cacaaaggaa gcttttggta tagttttagc tatatacaaa gaatgtttta
    32461 gcttgattac atcttttttt cccacgatga tcaaagtggg ggagttgatt ttttttaaat
    32521 cattttctgt aagcccgatg tcatgcagca aaagtttgat aactaaaaga tttttgcgaa
    32581 gacttgggcg aaataaagag agtaaccata cccatgcata atgaatatta ctgatgactc
    32641 tggcagaaaa acgaacgcct ttaacaagcg tgtttccaga atttaaaatc aatcgatgaa
    32701 cttttttagg gaagctgctg gcaaatacca gtgctagatt tgctccatca ctaaatccaa
    32761 gaaaatctgc ctgatcgatt ttttccagca acatgatcgt attcagatcc tcggccatta
    32821 actgaaaatt caacatagat gcttcgtttg tcgaacgacc atgtcctcgg ctatctacta
    32881 gatacacggt atagtagcgt tcgagtacag ggacctgttc tgaaaaaaag cggccgctgc
    32941 cgtcattgcc atgcagtaaa aagagaggga agccttgacc gctcttttca tagtaaattt
    33001 cgctcccatc tggcattttt gcatatttct tttctttttt cacataatca cctactgtgt
    33061 aaagtataac gattatatca gtcattgggc aattgttttt actgaaaaac aacgatcatt
    33121 ttcgtaagat gtcaaaaaat acaggaaaat tcattttttc ttaaggcgta cacagaaatc
    33181 aaggaagaaa tagccaagaa gataaagaaa tagtaagata aaaaaagatg tcaaaataac
    33241 taggtgatga aatgaagcga aaacgattat ctattatccg tattcttttt tacatgatca
    33301 ttctgacggt tattggtgcg gtgttgtttt tatgaggaag aacttatcgt tcggtaaaac
    33361 gagtggaaag ctatcaaata gaaataacaa cagctgcaaa aaattatcat atggaaaact
    33421 acgagaattt gatcaaggcg ataatattga ccgaatcaaa aggaaaaggg acagatctca
    33481 tgcagagctc ggaaagtctg catggagaag ctgagatcat tgataatcca gctgacagta
    33541 ttgatcaagg tgtcaaatat ttggcggaaa tgatagtaga agcaaagaaa caaggatgcg
    33601 atttatggac agctgtccaa gcatataatt ttgggaaaga ttatattgcc tatgtaaaaa
    33661 atcatggcgg agaaaacaca gtagaattag cagaagcgta ttctaaagat gtgctgagcc
    33721 cacttttagg aaatgaggaa gggaaacaat accgatattg gcggatccag tccttgcttt
    33781 acaatggcgg ctatctctat cataatggag gtaacatgtt ttatcctgat attgtcaaaa
    33841 tgaatgaaaa aataatagag acctatgaaa aagtctttaa gtaaaatagc aggaaatgtt
    33901 caatcatgaa taaaattaaa tgaaagaagg agtacgcaaa tagtggaaaa aaggcaaaaa
    33961 atggaaaatc aagaagtggg gtacacaacc aaagactgga tgttacggtt tgtgaaggga
    34021 atgtttatcg gttcaggatt tatcttgcca ggagtcagcg gtggtgcatt agcagctgtc
    34081 tttggcatgt atgagcggct gatttctttt ttagcccacc ttacaaaaaa tttcaaagaa
    34141 aatgttttgt tttttctgcc tgttggtcta ggcggagtga caggcatctt tctactttct
    34201 tttttagtca gttttttatt aggtgcgtat gaaacaacga tattatggtt ttttgtcgga
    34261 tgtatcgctg gaactgttcc tgcgttatgg aaagaagcag ggaaaaaagg aagagatact
    34321 tctgatgtga tcatcatggt tgttactttt gttctggctt atttgttttt attatacggc
    34381 gctcaattat ttgacgggca agtcgatcag aattttggaa catggctgat tgccggcgga
    34441 ttgattggtt tgggtatgat cgtcccagga ttgagccctt ctaatttttt ggtgtatatg
    34501 ggattgtata aagcgatggc tgacggattt aaagaagtac gacttgaagt gattgtgccg
    34561 atcggaattg gtgggattct ttgtgttctt ggattgtcaa aaatcatgga ttacattttc
    34621 tcaaaggcat atagcaagct attccatttc attttaggtg tagtttttgc ttcaacgatt
    34681 atgatcattc ctaccgatta cgcgggattg ggagttgctg gggtactagc ttgtcctgtt
    34741 ctttttatag ccggtacagc actaggttgg tggatgagcc gtttggagga acaatataag
    34801 taaagataga ttgataataa aaacagcaca cgggtgattc aaacaaaaag gttggcatct
    34861 tttttgtaaa atcattcgtg tgtttttcta taaattttat aaaaacaagt tgtttttaat
    34921 cttggaacac gctagactta aacacgtgat tatttttgaa agttggcgga aaatggagaa
    34981 aaagaaaatg aatggactta cacagcaaga ggtagttcag aaaatggctt ctggccagca
    35041 aaatgactac caggaagatg catcaaaaag tacaaaacaa atattcagcg ataatatatt
    35101 gacgttattc aattttctga actttggtat tgggatttgt ctgttatttg taggtgcgta
    35161 ttccaacatg gcgtatttag caattattgt cgtcaatatc gttattggaa tttatcaaga
    35221 aatacatgca agaaatcttg tacggaaatt atcgattgtt tcccaatcag aagtactagt
    35281 gatccgggac ggtaaagaac aatcgatttc tactaaagag ctggtattag gagatttggt
    35341 aaaaatcgga gcaggagaac agataccagc cgatttacag gttatatctg gacgggcaga
    35401 agcaaatgaa gctcttttga caggcgaatc tgatttgatt gtcaaagaaa ctggagctga
    35461 attgctttct ggaagctttt tgacaagcgg ttctgtcatg gctgaagtta tccgagtagg
    35521 tgcagataat tatgctgtcc gcttgactag cgaggcaaag actcacaaag ctattcgttc
    35581 tgaacttgta gattcgattc gcaaagtatc caaattcact agtttcgtga ttattccttt
    35641 ggggatcata ctatttttgg aagcactgtt catccgcgat gcttctatca aaatttctgt
    35701 tattgcatct gcagcagctt tgttaggcat gcttccaaag ggtttggtat tgctaataag
    35761 tattgcatta acgacagggg taaccaaact ggcaaaaaaa cgaatccttg ttcaagacat
    35821 gtattcaatt gaaacgctgg cccatgtcga tacattatgc ttggataaaa cagggaccat
    35881 tactgaaggg aaaatgagta tccagcgggt agaagcacta catccgctgt acgagaaagc
    35941 catcccagaa attatgggga cgtatctggc agaaagcagt gataacaaca tcactatgcg
    36001 ggctatgaga gattattttg agctttctaa tcggtatgat gtgacaaaca aagtcgcatt
    36061 ttcttctgat cgcaaatggg gcgcgatgga atttccagaa ctgggagtcg tgtacgtagg
    36121 agcgcctgaa cgtttggtgg aagaagatcg gcttccggac agtctaaaaa cagcccaagc
    36181 gaatggctat cgcgtactta tgttggggat cgctccaaat cagcaattga acgaagaaaa
    36241 accagcattt gttgagccgg ttgctctgtt tgaaatcgat gatccaatcc gaaaaaacgc
    36301 tcaagaaaca ctagcttatc ttcatgagga aggtgtggat ctgaaagtga tttctggaga
    36361 caatcctttt actgtctcca atatcgctag acgtgcagga ttaccgaatt atgatgcgta
    36421 tgtcgatctt tctcaaatta ctgaagaaat ggaagtgcga gaagctgctc atcgctatac
    36481 ggtttttgga cgagtgagtc cgcagcaaaa gaaattgctg gtaaatgaat tgaaagaaag
    36541 cggcagaacg gttgcaatga caggcgacgg tgtgaatgat gttttggcgt taagagaagc
    36601 agattgcagc attgctatgg cagaaggtga tggagcaaca cgtcagattg cgaatctggt
    36661 attgttggac tctgatttta ctacattgcc agaagtcctg tttgaaggac gccgagtggt
    36721 caacaatgtg acgaaagtct caggcatctt ttttatcaaa acgatttatt catttatttt
    36781 atcgattata tgtgccgtta cagcaattgg atttccgttt atccctatcc aaatcacgct
    36841 gattgattta gcgattgaag ggtatccttc cttcttttta tcttttgaac aagataaaag
    36901 aaaaatcact taccgttatt tgcctacagc acttattaat gctttaccaa atgccttgct
    36961 tgtagtagtg aatatcattg cggtgtatct acttggaaaa acattcgcat ggggaaatgc
    37021 tgaaactact actttgatgt attacttgct gattgggatc agttgcatgg cagttgtaaa
    37081 agcttgttat cccttcaacc cattgcgcat cttcctagca gtaacgacga tcgtagggat
    37141 atatgtagct gcaatgctgt tccatggaat tttggaagta aacttagggt tgggagagag
    37201 cgtaggatac ttctttgtat tcatgctcgt aaatattgtt cttcgagtat tgtactggaa
    37261 ggctgatatt caaaatcagt tactgaaaag agtagcaaat tgatgcttaa tgagatagaa
    37321 atgtgttata cttgaaaaag caatgaaata tgatacaatc aaacatgtat aattgtgtcc
    37381 tttaaaatcg cactgatttc agttagtgcg attttttacc ggttattctc ctgaaatatc
    37441 ttctgttaaa cccaaaagat atcaatagag cagggggtga aaaaatggct caacggattc
    37501 ctcaagaggt tatcgaaaca gtacgcagtc aaacgaatat cgttgaggtg attggacaat
    37561 atgtccagtt gaaaaagtct ggtaaaaatt acttggggct gtgtcctttt catgaagaac
    37621 gtacaccgtc tttttctgtt gcagaagaca agcagatttt tcattgcttt ggttgtggta
    37681 aaggcggaaa cgtgtttact tttcttcaag aactagaagg tctaagtttt ccagaagcag
    37741 tggtaaaagt ggcagacttc gaacagatac cgttagaaga tcaatggcgt cagcgtacta
    37801 tagctgtcca aaatcctgaa tctgctacgg ggaaactgat tgctgctcat gaaaaagcag
    37861 cggaaatcta tcatcacatg ctattgcata caaaagctgg acagccagct ttagaatatt
    37921 tgcaaagtcg tgggttgtct ttagaattaa ttgaagaatt caacataggt tttgcaccta
    37981 atgagcgttc ttttcttcag caagtattca agaatgaatc aatttcaaat gaattgttag
    38041 aacgctctgg attgtttgtc acgcatgatg atggccgtat gtctgatcgt ttttatcaaa
    38101 gagtgatgtt tccacttcgt aattctcaag gccagacgat cggtttttca ggacgctggc
    38161 ttgcacctga aaaagggcag gaaaaagatc agcccaaata cttgaatagt ccagaaacag
    38221 aactgttcaa taaaagacaa gttttattta atcttgataa agcaagaagc gatatccgga
    38281 aaaacggaga aattttgttg ttcgaagggt ttatggatgt gattgctgca tggcaggctg
    38341 gtatcaaaac tggattagct tctatgggga caagtctaac agctcaacag atccaacaaa
    38401 tggaaaagct gacgaaagaa ttggtctttt gctatgacgg agacaacgca ggttttgaag
    38461 caaccaatcg agggattgaa ttgcttcggc aaaacagtcg attagcactt tctgtcgtag
    38521 tcgttccaga aaagcttgat cctgatgaat atctccgtaa gtatggagaa gcatctttcc
    38581 aagaattagt ggctcatggg cgcgaaacag tctttacttt taaatcacgt tatttaaaac
    38641 aagggaaaaa tttagataat gaaaaagaca agatcgaata cctcgaagaa ttactagttg
    38701 aacttagccg agttgtttca ccaatcgaac aagatatgta tctatctcaa ctgtcaacag
    38761 agtttcagat cggcagagag acgatacaaa aacaactgcg cgatcttcga aggacaaatc
    38821 agcaaaatcg tcaagaacct caggaaagtc aacacactca ggttacgaga caagaaactg
    38881 cacggaaaaa gagacctttg acgcaagtag aaaaggcaga gcagattcta ttatatcgtg
    38941 catttaaaga agtttctgtc cgtaatattt taaaagaacg agaatttcag tttattcatg
    39001 atgcatatgc agaagtttat tttttattcg atgcatatgt ctcacaacat tatgaattca
    39061 accttgcaga gtttttagac tttttgcaag atgaaaattt aaggcggttg gtggtggaaa
    39121 tcgaatattt accggtggca gaagaaagtt cgccacgaga aatccaagac ttgctagatg
    39181 tgatcagcaa atctggctta gctgatgaaa taacattaaa aaaacaaatg cagcaagaag
    39241 ccagacgaac tggaaacaaa cagcttgagc ttgaattgac gattgaaatc atcaatttaa
    39301 cgaaacagtt aaaacaagcc aaatagctac tcaagggggg ccttctttta tggcaaatgg
    39361 aacagataaa aaaacgtatg aagcagcagt agcagctttc atcaaagaaa acaaacccaa
    39421 acgacaagtt gtatatgatg atttatccaa tcagcttgct acaccattca ctttgaatgc
    39481 agatgaaatg gacaaattga tccaaaagat tgaagacgca ggtatcagtg tggtggatga
    39541 aaatggtgat ccatcaattc acagcttgaa gagtgctgag aaaaaagctg aacaagcaaa
    39601 aacagaagat ctttctgcgc caaccggtgt aaaaatcaat gacccggttc gtatgtatct
    39661 gaaagaaatt ggccgtgtct cccttttaac tgcggaagaa gaagtagcgt tagcattgaa
    39721 aatcgaagaa ggcgaccaag aagcgaaaca gcgtctggca gaagcaaacc ttcgtttagt
    39781 agtaagtatc gctaaacgtt atgtaggacg aggcatgcag ttccttgact tgatccaaga
    39841 aggaaacatg ggactgatga aggcagttga aaaatttgac taccgcaaag gatttaagtt
    39901 ttcaacctat gctacatggt ggattcgtca agccatcact cgagcaatcg ctgaccaagc
    39961 acgtacgatc cgtattccag ttcatatggt tgaaacaatt aataaattga tacgtatcca
    40021 acgtcaattg ctgcaagacc ttggaagaga acctacgcca gaagaaatcg gtgcggaaat
    40081 ggatcttcca acagaaaaag tccgagaaat cttgaaaatc gcgcaagaac ctgtttccct
    40141 tgaaacgcca atcggtgaag aagatgactc tcacttaggt gatttcatag aagaccagga
    40201 agcaacaagt ccagcagaac acgcagctta tgagttacta aaagaacaat tggaagatgt
    40261 actagataca ttgactgatc gggaagagaa tgtccttcgc ttacgttttg gtttagatga
    40321 tggccggacg agaacattgg aagaagtagg gaaagtattt ggtgttactc gggaacgtat
    40381 tcgtcagatc gaggctaaag cattaagaaa attgcgccat ccttctcgtt caaaacaatt
    40441 aaaagatttc ttagaataag cgtggactat tgaccagaag agaaatcagt aaaactgttt
    40501 ggtttatttt aaaagaaaaa aagcttgaga ctacgcagtc tcaagctttt ttttctatag
    40561 gaaggaaatt cattcattat ttttaagtaa atcctaaaaa taagctattg gcgtgacgta
    40621 tagaatatga tagattaaat ggtagcgtaa acctagtaaa ggagccgatc gctaagtgat
    40681 gaaaaaatgt ccaaattgcg gatcgaaaaa aatggagcag aatactatct gtccagactg
    40741 cggtcatcaa ataactgcag aagatcagca aataaaagaa tcaattgaag aaacaaatac
    40801 agatgcagct atgcaggata aatcaactga agatgcagtc tttcctgata cagaattaaa
    40861 cgatccaatc gaatggtcgg aattgaaaga tttacctcta gaatctgtaa tggaattatt
    40921 cgaaaaagca gaaccagaag acgaagaacc acctgctcac gatcaagtaa ctaatataga
    40981 gaaaaatgaa cagaagaaag caactgttca tgagacttcg gaagaatcag gaaagaatca
    41041 agaagaaacg cttgaatcaa aacaaaaaag aagagtagct gaactgaaag aaatcgtcga
    41101 taatgaggaa gaaaattcga tactatccgc ttatatcaaa gcacatcgtg aagatacaaa
    41161 agaagagcac gcgaaagagc tgctcaaaat gatcagtgaa aaaattgcac aggaaaacaa
    41221 agtagagcca gaaaaggaac aagaaactga aaaagactct gatagagaaa acgccacagg
    41281 taaagaaaca gtaaaaataa aagacgtaaa aacggatatc acagaaaaaa ctgaagtatt
    41341 tactgaaaaa caattagaaa aggaaaaaac gaataaactg ccggaagcag agaaaaaaga
    41401 aatactcgaa aacacagaca aaaagtcaac agagcccgat gaaataaata gtgaatccga
    41461 tgctgaaaat caatctgtaa gcaaagaggg tactgatctt gaagcaaaaa tagaaaaaga
    41521 agagaaccag cctaagctgt ttgaagcaga agcgaaatca ataacaatcg tgccagatac
    41581 tgaaaaaaca catcaagaat caaacttaga aaaaacagat ccagataaag cgcaaaagaa
    41641 aaaatcaaaa aaagtacctt atctcgtttt agcagcagta cttctactcg gtggaggaag
    41701 ctgggcttat tatgaccatc atcaaaaagt agaagccgaa gtagcagcag aagcaaaaag
    41761 acagcaacaa atggaagaac ttcatgagaa acttgctgcc ttttatacag atgatcacca
    41821 tcaatttatt cgtgcagata tgattcatca agatttatca aaactaaaaa atgatttatc
    41881 cagtcttaag aatgaaaaag gatattcaga gttagaaaca acttaccaag atatccaatc
    41941 taagatccga gatatccaaa aagtgaatga gtggttcata gcacctgcca tcgtcgatga
    42001 tcatctagca gatgacatca agttgaaagc agataaagag atccaagcaa tcgaaacgga
    42061 taacacagat tttggaaaat tgattcaaca agcacaaaca gaagctaaaa atcaatatgc
    42121 tgaattgcaa acagctaaag aaaaaacagc tatagtcttt aaagacggaa aagtagtgga
    42181 ttcagcaaca cgcgaccaat acaagacggc aaaagaagca gtagaaaaag tgaaaaatac
    42241 agatctatct gctcagttga atgaacaatt gaaacaagta gataagatgc tcactgataa
    42301 agagaaaaaa gaagaagagg aaaagaaaaa agcagaagaa gcgaaaaaag cagctgaaga
    42361 acaagcaaaa caagccgctc aagcagcagc tgcagctcaa gccgctcaac aagctgcggt
    42421 cgcacaagca gcacagcaag aagcggcatc ctcgacccct tcctcttcaa actcagcgaa
    42481 tcagccaatc aaatctgcca gagcaagtga tattgccgat gcatctaatc cagcatggac
    42541 gtgggcacca ggtgtccaaa gcaaagtgat tgctacatgt atccaacgtg gatatatcgt
    42601 tgaaggaggt tacagattag aaaaagccag aatcgaaaat ggggaaggct attataatct
    42661 atatgccact tcaacaaaat ctgcattgat gaaaggcatt ggagaaagtg ctttgccatt
    42721 ttacatcgta accatcaact gtaaaactgg atggttcgga ggaaatggga gcaattaatt
    42781 ttaggcaaat gaaagaggct gtgagcctgc cgtttaacac cgtttattcg aaaaagggga
    42841 gtatgacaca actgttgtca tactcctttt ttcacctttc caaaccaagg ctcagctatt
    42901 caagtagata acattatgtt atgatagcaa agaaatgtat taagaaaacc tttcactata
    42961 gagggagaaa aaaatgaacg atttattagc aactatattt acaggtatta ttattgatga
    43021 aaatgaaaaa aactactttg tccaaaaaaa cggacaaacc tttggcttaa gcaaatcaga
    43081 aggtgaacac aaaatcggtg aagcagttga aggattcggt taccaaaatc aaaaacatga
    43141 aaatcggatc actacacaaa ttcctaaaag ccgtatcggt cattacgctt ttggaatcgt
    43201 tactgctaca cgaaaagatt taggtgcgtt tgtcgatatc ggtcttccag ataaagactt
    43261 tgtcgtatct cttgatgaat tgccgacaat gacagagcta tggcctaaaa aaggggatcg
    43321 cttgatgatt tcccttagag ttgatgcaaa agaccgtatt tggggcagtt tagcagatga
    43381 aaaaatattc aaatctttaa gcaaatatgg aacagaagaa atgaaaaaca aagatgtgat
    43441 aggaacagca taccgcttga aattaacagg tacgtacgtt ttaacggaag atttctatct
    43501 tgggtttatc catccttctg aacgatataa tgaacctcgt ctaggcgagc agataaaagg
    43561 tcgagtgatt ggtgtccgac cagacggtgt actgaatctt tcattgaagc caagagcata
    43621 tgaagctata tcagatgatg cacaaatgat tttaaccatt ttagaacgtt ctgcagatca
    43681 gcaaatcaac tttacagata aatcggatcc agaagaaatc atgaaagctt ttggtatcag
    43741 caaaggagca tttaagcgcg cattaggtaa tcttttgaaa caaggattga ttacacaaga
    43801 aaacggtgtg acaaaactag tcaaaaaatc taattgagaa tcccttgcat gtttttctta
    43861 actagcttat aataatttta attaacatag tgttatatct ttttttattt gtaattatta
    43921 taaattgttg gggttgagta aatggtcatg aatgctattt cggcgatgaa aaaaacaaaa
    43981 cagcagctac atgaagcggg gtttaagctg acaccgcaaa gagaagctac tctgcttgtg
    44041 cttttggaaa atgagaaaga gcatttatct gcagaagaaa tcttcttttt agtgaaaaaa
    44101 aagagtccgg aaattggact tgctactgtt tatcgaaccc ttgaaatctt gacagaattg
    44161 aaaattgtcg ataaagtaag ttttaatgat ggattagccc gttatgattt gagaaaagaa
    44221 ggcgccaaac atttccatca tcatttacta tgcttgaact gcggcacgat cgaggaagta
    44281 gaagaggatc ttttacttga agtggagcaa gtagtagaag aacgttatca ttttttagta
    44341 aaagatcatc ggctaacgtt ccatggaatc tgtcaggaat gctatgaaaa agaaaaaaga
    44401 aaccagtccg tctgagtgtc tagacggctt tttctttgct cagattatgg aaaaagacta
    44461 tcagaatgaa gcggtatctg atatgataga gaggcatgag ggggattatt atgaaagagc
    44521 aaatcaacga ttatctccac tacttgaata ttgaacgggg attgtccgcc aatacacgac
    44581 aaagctatga acgtgatttg gaacagtact tgcattttct acaggagcag aaaattgctt
    44641 catggcagga tgtcgatcgc tttttagtca tccgttttct ggagaagttg catgaagaaa
    44701 aaaaagcgac agcaactgtt actcggatga tctcaagtct cagaagattc catcagtttt
    44761 tacggcaaga gcgtatcact gatcatgatc cgatgcaaca tatcgatacg ccgaagaaag
    44821 cacagaaatt accaagtaca ttgactctga cagaagtaga aaagctgatt gaagcacctg
    44881 atacgacaaa aacgttaggg ataagagatc gtgcaatctt ggaagtcatg tatgctactg
    44941 ggatgcgcgt cagtgaattg attggattga aattgggaga tcttcatctt tctcttggac
    45001 tggtacagac agttggaaaa ggagataaag agcggatcat tcctttaggt gattatgcga
    45061 tccaatggct ggaacgctac ttagacgaag cacgtccatt acttgtaaag gacgcatctg
    45121 aaatgcatgt atttgtcaat aatcatggga aaggtctttc tcggcaagga atctggaaaa
    45181 atctgaagca gttagtacga gaggctggga tttacaaaga agtaacacca catacgctgc
    45241 ggcatagctt tgccacacat ctgctagaaa atggagctga tttgcggaca gtacaggaat
    45301 tgttaggtca cgcggatatc tctacgactc agatttatac acatatcacg aagaaaagaa
    45361 tgacggatgt ttataagcag cattttccaa gggcttagtc ataggaaggt gagaagatgt
    45421 taacacatta ccggaaagaa aaccgtaaaa ttgctatggg actattgagt ttccataaga
    45481 aactgacagg taaaacttct ttgttgaagg agattgatac gtacgaatct gaagacgatt
    45541 atgaactttt tttctttacg ccagaaggtt caaccaacat tcaagggatt attggtattt
    45601 actgggcaac gaacgatcag ctgatcatcc atgacatttc tttgaatccg tcttatcgcg
    45661 gtgagaatat gggctttcaa atgttagatg aattacagga aaagtacccg gatgtctcca
    45721 tccgtgcaac tgaaatcaca gagccttaca ttggaaaatg gctagcaaag aaaaagaaga
    45781 aagagtgaat gagttgacgg agatcaatat taaattagat gtattcgagg gtcctctcga
    45841 tctgctgctt catctgattc agcaaatgga aatcgatata tatgatatac cgatcgctac
    45901 gatcacggag caatatatga attatatcca tacaatgaaa acactcgagc tagctgttgc
    45961 aggagaatac ttagtgatgg ctgctacatt gatggcaatc aaaagcaaga cattgcttcc
    46021 tgtccaagaa ttcgtcacag acgatgaaga attatgggaa gaagatcctc gagaagaatt
    46081 ggtcactcag cttttagaat accgtaaata taaatatgca gctgaaagac tgacagaaaa
    46141 agcagaggaa cgaagtcttt attacacaaa agaacctatg aacatcgatg ggttagcgga
    46201 tgctgaaaag ccgttgaagc gaggacaagt caaaaaaatc gatttgatcc gtgccatgca
    46261 gaaaatctta gaacgtaaga aattttctca aaaagtggaa aaaacgatca cgcccgatga
    46321 cacaacgatc gaagaacgaa tggtatttat cgaagagcgt ataaaaagaa atgcgcatgg
    46381 ctgtactttc gattcttttt ttgagtcacc ttctaaaagt gaagttgtca ctacttttat
    46441 ggctttgcta gaattgatga aaaaagggca gatcattgcg caacaaaaag aaaactatga
    46501 atcaattatg ctttatccag cagtaggaga taccgaacat gacgaaatta agtgaacttg
    46561 aagcccttct ttttattgtt ggcgaggaag ggatcagtaa tgaagaatta agcggactgt
    46621 taaatctcag cgaagcagaa gtcacaagtt tagtgaaaga attaaaagaa tcttacactc
    46681 aaaactcgca ctcagctttg catatttttg aaacggaaag ccattatgta ttaacgacta
    46741 aaaaagagct ggctccctta cttaagcgat atgcgcaagg gacatcaaac acattatctc
    46801 aagccgccgt cgaaacctta gcaatcatcg cttataaaca gccaatcaca agagctgaaa
    46861 tcgagcagat tcgaggagtt caggtttcag gagcggtaca gcgtctagct gcccataaac
    46921 tgattgaaga aaaaggtaga gtagaaggac caggtcggcc gatattatat ggaacaactg
    46981 gctacttctt agattatttt ggtttgaaat cattagaaga actgcctgat acacaagaaa
    47041 tggaaatttc acttgaagaa gacgtgtcac cagatctatt ctttgatgga atgaataaag
    47101 gagaataatt gtaatggaga gattgcagaa agtaattgcc cacgctggca tcacttctcg
    47161 tcgaaaagca gaagaattca tccttgcagg acgtgtaaaa gtaaacggac aagttgtaag
    47221 ggaattaggg ataaaagttg ggaaacatga cactgtggaa gtggatgaag tcccaattta
    47281 tcaagaagaa tacggttact atttattgta caaacctaaa ggagttattt ctgctgttgc
    47341 agatgacaaa ggaagaaaag ttgttacgga tcttttgccg atggtaaaag aacgtatcta
    47401 tcctgtaggt cgactggatt acgatacttc ggggatcttg ctactgacaa atgatggaga
    47461 ttttgctcag cgcctgacac atccaaaaca tgaagtggat aaagtttacg ttgcaaaggt
    47521 aaaagggatc gctacaaaat cgatgcttgc acctttgaca aaaggaataa agatcgaagg
    47581 acgaaaaaca tctccagcta aattccaaat tttatcagtg gatcctaaga caaaccacag
    47641 tatcgtggaa ttgacgatcc acgaaggacg taatcatcaa gtgaaaaata tgcttcaagc
    47701 agttggtctt cctgtgcaaa aactaaaacg tgaaaaatac ggagatctga ctttacaagg
    47761 cctacgtcct ggggattacc gtgaactgaa caaaaaagaa gtcagcagtt tgctgaacca
    47821 ctcaaaatga acacttactt tttataagtg ttagatgttg cgttttttga atagatatgt
    47881 ataatgaata tgtaaacaaa aattatataa ggttcgtctt caggggcagg gtgaaattcc
    47941 cgaccggtgg ttatagtcca cgacctattt tgcaaaaaaa tagctgaatc ggtgaaattc
    48001 cgataccgac agtatagtct ggataaagaa gatagagctt atttgacgac gcttgatcaa
    48061 ataactctaa ctctattttc cctggaaaat agagtttttt catttggaga gaaacgtcaa
    48121 aaagttcgct gaagaggagt cctaacagga ggatttcaaa tgaagaacac ccgtgtacag
    48181 aaaatggttg cagtagcgat gtttgctgcg atcgcattag ttttacagta ttttgctttt
    48241 ccgatcatgc cggcttttag ttttttgaag atcgatttta gtgatatctc ggtattgatc
    48301 agcatgttct tattcggtcc agcggccgga gttgcaacag cgttcttgcg ttcagtatta
    48361 catctgctga ctacaggttt ttctccggat aatttggtag gagacactgc tagtttctta
    48421 tcaacaacga tctttacatt cccgatttat tatttcttta gtgtaaagaa acagcataaa
    48481 ggaagaaaca aatttttagg tgtcattaca ggaaccatcg ctctaactat ttttatgagt
    48541 atcgcaaatt atttcgttat tacgcctctt tacttaatgt ttttagggct gaacgcaaca
    48601 cagatgctgg gcatgtcttt agcaaactat gtactgattg ggatcgttcc tttcaacttg
    48661 atcaaaggat tcatcgtgag tgctgtcttt ttagtgctgc atgcgcaact tcttccatgg
    48721 ttaagtcgaa aacaacatca gttcgaacaa cgtcatacag cagtcaaata aatatcaaaa
    48781 agatcaagaa atttcttggt cttttttttt ggaaaaaaat acaagacatg caataatgta
    48841 aacgttttat ttgtttgttt tgagtatttt tttgatttat gcataaaaat caatcaattc
    48901 tttgcaaatg tgaaattctt ctccttttaa aagacgaaaa tgtttgttta taaaaaaaag
    48961 gaaacgctac aatgaaaaag aagaaagctt taaaaacctg aaaaaagagg agggaatagg
    49021 gaaaaacgaa ctttttgaac aaaagtttta caaaatgcgt gttattattt ttgttctgat
    49081 actctttttg ataaaataac attagagcca aaattgttgt ctctaacgga aaagaaagga
    49141 agaagaagat ggaacaaaca aaaaagaaaa aatttcaaat gccttcagcg tatacggtct
    49201 tatttattat tattgcagta atcgctgtac ttacttggtt tataccagct gggcactata
    49261 gtgtagacga tgcaggcaac atcgtcgctg gatcatatga acgagtacaa caaaatcctc
    49321 aagggctgtg ggatattttc atggcgccaa tcaatgggat gctaggtgta ccagcggggg
    49381 agctaactaa agaaacacct gctgcaatcc caatctcttt cttcattttg gttgttggtg
    49441 gatttttagg tattatcaac aaaacagggg cactagatgc cgggattgct tcagttgtga
    49501 agaaattcaa aggaaaagaa aaaatgctta ttccagtatt gatgctgtta tttgcattag
    49561 gcggctctac ttacggaatg gcagaagaaa cgattccatt ctatgcttta ctgatcccag
    49621 tcatgatggc tgtaggcttt gatacagtag tagctgtagc aatcgtatta gtagggtctc
    49681 aagtaggctg tctagcttca acggtaaatc cttttgcaac aggcgtagct tcacaagctg
    49741 ttgggatttc gatgggtgaa ggtattggtc ttcgattctt gatgttcgtt attttgttag
    49801 ctatttctat tgtatatgtg tatcgttatg catcaaagat cgaaaaagat ccaacaaaat
    49861 cattagtata caaccaacgt aaagaagata tgaagcattt cgatattgaa gcaatcggtc
    49921 gtcaagaagt aatcacgaaa aaacaaaaac atgttaatgt attgttcttt attacttttg
    49981 gtatcatgat catcagtttg attccttgga caaccttgaa tgcgaatttc acgatttttg
    50041 aatcattgac aaactggtta acaaaccttc cggtactagg tacggttcta ggtaaaagca
    50101 tgcttccatt aggtgactgg tacttcccag aaattactat gttattctta gtaatgtcca
    50161 tcgtagtagc aatcacttat ggcatgaaag agtctgaatt tgtctctgaa tttttagctg
    50221 gtgcttctga tttgatcggt gtagcaatcg tagtagctgt tgctcgtggt atccaagtgg
    50281 ttatgaacaa tggattaatc acagacacca tcttacattg gggcgaacaa ggattaagtt
    50341 cattatcttc aagtgtattc atcattatta catttatttt ctatatccct atgtcattct
    50401 tgattccttc aacttccggc ttagctgctg caacaatggg aatcatggga cctatgggtg
    50461 aatttgccgg cgtcggtaag gatttagtaa tcactgctta tcaatctgca tctggtttag
    50521 taaacttaat tacaccaaca tctgctatcg taatgggtgc tgtagcaatt gctcgtttcg
    50581 atgtttcagt gtggtggaaa tttaccggta aattaattgc gatattattt gtagccatct
    50641 gtgtgatcct aggtgtagca gcaatgttct aaacctagac aaatacaggt acaaggtcta
    50701 tcataagaat gaagaaaccg ataaacggct atcgataagc acgtggataa gtcaatagct
    50761 ccattcagtg agtgtttttt ctttcatcat ttgttaagaa cattctgctt gctgatggag
    50821 caggcttaaa acgtcattat ttgagaagaa gaggttgtgt cggaggaatt tgacatgacc
    50881 ctttttaaca tattaggagg ataatatcat gaaaaaattt gtgacagaac aacatcatga
    50941 acaagcatta gaatcattga gcgaattgat ccgaattcct tccgtactag atgaagcaga
    51001 ttcaggacaa ggacatccct tcggtaaaaa agtgattgaa gctttggata aagtattgga
    51061 aatcagtgaa aagctaggat ttagaacatt taaagatcca gaaggctatt acggttattc
    51121 agagattggc tctggagatg aattattcgg tatcttgtgt catatggacg ttgttccagc
    51181 aggggacgaa aataattggg aaacaaaacc attcgatcca actataaaag acggctggtt
    51241 agttggtcgc ggatcccaag atgacaaagg tccttctatt gcggcaatgt atgccgtcaa
    51301 agctttgatt gatgctggcg tggaattcaa gacacgtatt cgttttatct ttggtacaga
    51361 tgaagaaaat ttatggcgtt gtttagaaaa atataacgaa aaagaagaag gaattacgca
    51421 aggatttgcg ccagatgctg aatttccttt aatttatgca gaaaaaggct tattgcaagc
    51481 ttacttgaca ggaccaggaa cgaacgagtt ttctgtaaaa gctggaggag cgttgaatgt
    51541 tgttcctgat gcagctcctt actctggaga aaagctttct gaagtaaaag aagcattgaa
    51601 aaaacacgaa ttcgatttcg aagaacaagg tgaaggcatc gtcgttcttg gtaaaagtat
    51661 ccacgcgaaa gatgcagcac aaggagtgaa tgctatttct cgtctggcaa ttgctctttc
    51721 agaagtattt gattttggcc caatcaattt cttaggaaaa ttagttcaag aaaatgcaac
    51781 tggtgaagct gtcgtgggca aaacagaaga tgaacaatcc ggcgagctaa cgatgaactt
    51841 tgcaagtttg gaaatcacac cagaacaaac aaaaatcggt gtagatatga gaatccctgt
    51901 tacattcaag aaagatgatt tagtagctaa attaactaaa acagcagaaa aatatgggtt
    51961 gacttatgaa gaatttgact tccttgattc attatacgtg ccactagaca gtgagttagt
    52021 gaaaaatcta ttggggacat atcgcgatat tactggagac atgactgaac cgtttgtatc
    52081 aggcggcgct acttttgctc gtacgatgaa ccagtgtgtg gcattcggtg cgatgttccc
    52141 tgatactcct gactttatgc accaggcgaa tgaacgatgg gaattaagta gtatgtataa
    52201 agcaatggaa atttatgcag aagctgtgta tcgtttatgt gctaaataaa aataaacata
    52261 caaaaagggc ggatattcaa atggatattc cgtctttttt tatttgatgc tggaaagttt
    52321 gcatttctct cttatttttt taaggtataa tcatacttga ttaagaaaaa ggggtcactc
    52381 agatagaaaa ggtgggagaa agtgaaaata tttagacgaa tactaattgg cttagtcatc
    52441 attttaggat tactcggtgg agccggttat tactatatac agcaaaatac gtacgaacca
    52501 tcgtcagaag cgcaagtgtt ggtaaaagaa ggaaaaaaca aagaagatta cttatttttt
    52561 gaaggagaga aaaagaatca tggaaagtct ccattactta ttttttatcc tggtgctctc
    52621 gtagagccag aaagttatag tatttgggcg caagatttag caaaaaacgg cttttcagtc
    52681 gctattgtca aaatgccact tgatctagca gtgatgggcg gaaacaaagc ggataaggtc
    52741 aaagaagatt ttccaaattc cgattatgtg atcggtggcc attcattagg tggcgtaatg
    52801 gcaagtcgtt atgtcaataa gaatcattca gacaaacatt taaaaggggt attcttcatg
    52861 gcaagttatc ccgacaaaaa aggaacattg acagaatcag ctgttcctgt tttatcgatc
    52921 acggcgacaa aagataaagt attgaatcag gaagcttatc aagaagctaa gcagtattta
    52981 ccggaaagaa cagagtatgt atcaatcaat ggcggaaatc atggaggttt tggcagctat
    53041 ggtgagcaaa aaggagatgg agaggcagaa atttctaacg cagaccagca aactgtgatc
    53101 gtcaatacat tggaaaactg gctgaaaaag ttgaaataat ataaatgggt cctatagggt
    53161 ccgtgaaaaa actagtcaat taactataga tagcaaatga atctttcaaa ataagtcggg
    53221 atttcacgga acaagagaaa cagatcccgg cttattttca agtttagaga acttagtgta
    53281 cgtttttaaa gtttcgttta tatttatatt ttattttcta ataaaatcgc tcgaactgga
    53341 catttttgat acgctttttt tacatatgtt tcttcttccg gcatcacgaa ctgttgatga
    53401 gcctctggtt cttgggcaaa taaaacgatt ccttcttcat cataatcgaa aatatctggc
    53461 gcttcgattt gacaaagacc gcatgcaata cagcgttcag gtacaagttt acatagtagt
    53521 gacatttcta accatcctaa cttaaggaga ataatatgat tgtttttatt ttatcgctat
    53581 tttcatcagg acacaagctg cggattagtt ctctttacca actccttgtg ggaaaacgaa
    53641 cgacttcagt acttatttat ggatttaccc acgaactttt gtttatccat aacagttttc
    53701 cagaattgaa gcaggataag ttttatcaaa ttttgcaaaa aattgcgcag caaggttgga
    53761 tcgaaataaa tgaaaatgaa gcaaagctaa cgcctgcagg ggctgatatg ttgtccgaac
    53821 atcaaataga acatactggt ttgcgttttg accgctatgg cagaacaggg gaaactagtt
    53881 ggcggctcat taaatttgct gttcaagtaa tttctaatct ggcaacgggt attcaagact
    53941 atcttccagc agagacaagt cctttttata ctttccaact aaaaaaatgg cttagtgaaa
    54001 gccaattgcc acgtgaaatt ttgattgata ctgcgtatga gagtttggtg cagctgtttt
    54061 cggagatacc agaagaagca gcagattttt tagctaacca attatctgga aatgagcgaa
    54121 cagggctgct tccttatcag ctggcaaaaa acaatgatga gtcagcggtt tatctgcaac
    54181 aaagcagatg tatccacctt ttgttagcac aaatcgaaaa acggccagat tcgctttggc
    54241 acgctttgat cgattcatta ttacagcaaa atttcaatca aagcatgatg atcaccaagc
    54301 agatgtttat gaatggtcag acaattgacc agatcatggc aatccgtcat ttaaaaagag
    54361 gaacagtaac agatcatctt attgagtggg ccttgttttt tgatgatttt ccatacgagt
    54421 ggattctctc tgcagaaaca atcgaacgtt tggaaccaaa taaggattcc gtgcgagagt
    54481 ggcgctttag cgaatggaat gtagatggac aattagatta tggagaattt cgtttgtatc
    54541 aaatctatct attgagaaag gaagcgatac agaatgttaa taaatgaatt aaaaaaatat
    54601 tttggatttg attcatttcg tcccggccaa gaagaaatta ttcaggcgtt gcttgatgga
    54661 gaagatactc tcgctatttt gcctacagga acgggaaaaa gcctttgcta tcaattgacg
    54721 gggtatttaa tggaaggtct ggtcatcatc gtgtcaccgc tgctttctct aatggaagat
    54781 caagtgacgc aattacaaaa acgaggggag aaacgagtag ctgctttcaa tagtttactt
    54841 tcgcaatctg aaagaagata cgtcctccgt catctatcgc aatataaatt tttgtttttg
    54901 agtcccgaaa tgttgactaa tccttctctt ttagagcatc tgaaaaaaca aaatattgcg
    54961 ttatatgtag tagatgaggc tcattgcgtg tctcaatggg gagttgattt ccgtccagaa
    55021 tatcaacagt taggaaaaat ccgaaagctt ttaggaaacc cggtcacact ggcactaacg
    55081 gcgacagcaa cagatttagt agcaagagat atacgtcatg tactatttga tcgaccacca
    55141 aaagagatca gacaatcagt caatcggcaa aatatctcgc tttttgttcg gaaaacgcag
    55201 caaaaagaac aagaacttga acacttcatg gaaagagcac aaggagcggc aatcatttat
    55261 tgtgcaacaa aaaaagaagt cgaacgattg tatcatttat tcagggaacg ttttacagtt
    55321 ggatactatc acggtggtct tgatgcagct caaagaagac aacttcaaca gcagtttgta
    55381 aaaaatcagc tgcagtttct cattgctacg aatgcatttg gtatggggat cgataaatct
    55441 gatatccgtt atgtggtcca ttatgatttg ccagacagtc tagaaaacta tgtacaagaa
    55501 atcggtcgag caggcagaga tcaggaagaa agtgcagcaa ttctttttta tcaaagtggg
    55561 gatgaacgta tccattattt ctttaatcaa ctttctagag aacagcgaca aagttttgag
    55621 ctttatttgg aatatgccac agagcaagct ccctttgatg agctgcaaaa aaaatggatg
    55681 gagctgatcc agcagtctga aaaaccagaa aattgggtgg aacggctcaa acgtcaggaa
    55741 aaagaaaaag aattccgcct gcagcagatg cttcgctata ttaatgaaga aaactgccgc
    55801 agaaaattca tcttagctta ttttggcgaa aaactctccg aaaagccgca gaattgttgt
    55861 gatattgatg gagcaaaagc agaacttctg ccaaagagga agcttttttc taagactgaa
    55921 caacttcatt ggggaacgat tttactaaat ttatttaaaa aaaacatgga acattgattt
    55981 tttaggacaa gacacttttt cctatggtat aatacacacg atagagttta ggaggtaaaa
    56041 cagtgagcag aaaagataga catcaatcta cagaaaataa cgaaacacaa gaaccatggg
    56101 aacaaccaat ctacgataca gatgatgaag tttcatcaag aagttctcag agacaacaaa
    56161 agaaaggaaa tacattattt ctttcgctat ttttgatttt actggtctta tgtatcgcta
    56221 ttccagcagg tgcttatttc tggatcagaa atggatcaag caacaatgca acagcagcaa
    56281 cttcttctga aacttcgaca tcagtagtag aaagttctac aagtacaaca aaagaggagt
    56341 caactgagac ttcaacagta gaatctagta caatcgcgga agaatctact gtgtctcaag
    56401 atacaggtgt aacgtcagaa agcagtattg cagcagagac aacaccgact tcctcaagtg
    56461 aggcaactta tcaagcaggg gattcaagca gcaatgcagc agaaacaaca ccttcttcat
    56521 cagctgcagc cggttcaaca acgactgttc aagcaggcga aggtccaaaa caagtggctg
    56581 agcgtgcagg gatcaccact gatcaattgt ttgaattgaa tggcttagat ccaaacaact
    56641 ttatgcttta ccctggtcaa gaattaagaa ttaaataata atagccgcgc tttgcggctt
    56701 tttttctgag aaaaaggagt tatatcatga cacaaatcag tattgcaatc gacgggcctg
    56761 cttcatctgg gaaaagtacc gttgccaaga tattagcaaa agaattgaat tatatttata
    56821 cagataccgg tgccatgtat cgcgcagtaa cttatttagc tattacgaac aatgtatctt
    56881 tttcagatga agaagggcta gtttcgctga tcaaaaagta tcctatctct ttttcgcaac
    56941 aagaagatgg acagcatgta ttcatagcat caaaagatgt gactttagaa atccgtcaac
    57001 cagatgtcac aaaagctgtt tctgaagtct ctgcacatgg aaaagtcaga gaagaattag
    57061 ttgctgtcca acgaaaaata ggggaacgcg gtggcgttgt catggacgga agagacatcg
    57121 ggacagctgt attaccgaat gcagaagtga aaatcttttt agtagcaagc gtaagtgagc
    57181 gtgcagaaag acgtttcaaa gagaaccaag aaaaaggaat tccgactgat cttgaaacac
    57241 tgacgaaaga gatacaggaa agagaccatt atgattcaac aagggacgtc tctccgctga
    57301 agcaagcaga ggatgctgtt cgtatcgata cgactggcaa atcgattcca gaagtcgttg
    57361 cagcaataaa agctgttgtt ttgaaaaaag gttatcttct tttttaaatt aagaaaaaaa
    57421 atgaaaaaca attgtttttt caaggaaaac gaacgaaatc gctttatttt ttttgaataa
    57481 tcaattaaac taaaaacagt accgtactta cggcagaatg ttggttagga ggacaagtgt
    57541 tatgacagaa tttgatcaaa atcaagagaa caaccagtca atggaagacg caatgaaaag
    57601 cgtacaagaa gtaaaagttg gcgatgttgt taagggcgaa gttttagtca ttgaagacaa
    57661 acaagtgatt gtcggaatcg aaggggctgg agttgaagga gtcgttccgg caaaagaatt
    57721 atcaactttg ccggtagaag atatcagcga agtagtaaaa gtcggtgatg tattagattt
    57781 agtcgttatc agtacgatcg gcaaagataa agaaaacggc agctatctac tttcaaaacg
    57841 ccgtttagat gctaaaaaag tttgggaaga tatcgaaaga gatttccaag agggcaaggt
    57901 catcgaagca cctgttacaa atgttgtcaa aggcggttta gtcgttgacg tcggtgtacg
    57961 tggttttgtc cctgcatcaa tggtggaaga tcattttgtt gcagactttt cagactataa
    58021 aggcaaaaca ttgagcttta aaatcatcga aatcgaacca tcagaaaatc gtttgatctt
    58081 atcgcataaa gcggtagtgg aaaacgaaag agaagaaaag aaaaaagaaa ttctttcaac
    58141 tatccatgag ggagatgttc tcagtggacg tgttgcacgt cttactgatt ttggcgcatt
    58201 tgtcgaccta ggcggaattg acggtctagt ccatgtctca gagatttcac atagtcatgt
    58261 agcaaaacca agtgatgtat tggctgtcaa tgatgatgta aatgtcaaag tgttgtctat
    58321 caatcctgaa caagaacgtg tttccttgtc aatcaaagac acacagcctg gaccttggtc
    58381 agaaatcgat acaaaagctc cagttggcac agtattagac ggaacagtta aacgtttgac
    58441 aagcttcggt gcctttgttg aagtgttccc tggagtagaa gggctagtcc atatctctca
    58501 aatttcacat aaacatattg cgacaccaca tgaagtgctt catgaaggtg acgaagtgaa
    58561 agtgaaagta ttagagatcc atccagaaga acatcgtatt gcattgagta tcaaagcttt
    58621 agaagaaaaa ccagcttcag aagaagaacc aaaaaatgtt gagtcttatg aattaccaga
    58681 agaaaatact ggatttacta tgggagacat tttaggtgat gcgttgaaag aagaagtaga
    58741 agaaaaagca accgatgatt ctgaaaaata attgattttg tatctgtgac tgagatgaaa
    58801 gcagctgctt ttgtctcagt ttttcttttg aaaagcgatt agtatttcaa taaggaataa
    58861 aaatacttcg tttaattgac aatctatgct tgaaagttgg caatgcattc gttaaactaa
    58921 gtgagattgg aaacttgtga ggaggaaata atatggcaaa tccaacaatt gcaatcgttg
    58981 gccgcccgaa cgtcggtaag tctacgattt ttaaccgcat cgctggtgag cgtatctcga
    59041 ttgtcgaaga tactcctgga gtaactcgtg atcgtattta tgcaaaaggt gaatggttag
    59101 gtcgagaatt cagcgtgatc gacacaggcg gaattgatct tggcgatgaa ccttttatgg
    59161 atcagatcaa gcatcaagca gaaatcgcga ttgaagaagc agatgtaatc atttgtgtag
    59221 tcagcggacg cgaaggcgtg acagacgcag atgagatggt tgcgaaaatt ttatacagaa
    59281 gtaataaacc agtgatttta gcagtcaata aagtagataa tccagaaatg agaaacgata
    59341 tctatgaatt ttattcctta gggctaggcg atccttatcc tgtttcagga agccatggac
    59401 tagggattgg tgatatttta gatgaagcag tgaagtattt ctctgaagag actgaagaag
    59461 aggacgacga cacgattaag tttagtttga ttggtcgccc aaatgttggt aaatcctctt
    59521 tgatcaatgc gattttagga gaagaacgtg taattgtttc ggatattgaa ggaacgaccc
    59581 gagacgcaat cgacacccac ttcgtttctg aaagtggtca gaaattctta atgatagata
    59641 cagctggtat gcgtaaacgc ggaaaagtat acgaaaatac tgaaaaatac agcgtgatgc
    59701 gtgcaatgcg tgccattgac cgttctgata tcgttttgat ggtactgaat gctgaagaag
    59761 ggattcggga acaagacaag cgagtagcgg gttacgccca tgaagctggt cgtggaatta
    59821 ttatcgtcgt gaataaatgg gatcttgtaa agaaagaaac caatacaatg cgtgatttcg
    59881 aacaagagat tcgtgatgaa ttccggtatc ttgattacgc tccaatcgtt tttgtttctg
    59941 cagtgactaa acaacggttg gaacgtctgc ctgaaatgat cgaacaagta agtatgaacc
    60001 agaatcttcg tatctcttcg gctgtgttga atgatatcat tatggatgct gtagcaatca
    60061 atccaacacc aacagataaa ggaaaacgcc tgaagatttt ttatgctaca caagtcgctg
    60121 tcaaaccacc tacatttgtc gtttttgtca atgaagagga attgatgcat ttttcttatg
    60181 aacgtttctt agaaaatcaa atcagaaaag catttacttt tgaagggacg tccatccgaa
    60241 ttatccctcg taggagaaaa taggcatttt accatatcga cgtttttttt tcaaaagaaa
    60301 aagacagttt cgtttgttac gtttctatga ctaaaaaaag catgtgaaaa ttggtaaaaa
    60361 ccttgctatt aagcggttca tatgatatcg tgataacaga atattgaagt taatcaatat
    60421 ttctttttaa acttctggac cactcagaaa gttttaacta aatgatattt ctatcatatc
    60481 tcttgtggag gaggtgaatc tatccatggc aaacaaagca gaattaatcg aaaaagttgc
    60541 ttcagctact gatttaacta aaaaagatgc aactgcagca gtagatgctg tattttcaac
    60601 tattcaagat gctttagcta acggcgaaaa agttcaatta atcggttttg gtaactttga
    60661 agttcgcgaa cgcgcagctc gcaaaggtcg taacccacaa actggtgaag aaatcgaaat
    60721 tccagctagc aaagtacctg cattcaaacc aggtaaagca ttaaaagacg ctgttaaata
    60781 agacagttga aaaagcgctt gtggctctag ggctacaagt gcttttcttt ttatttccta
    60841 gcagaaaagg aataaataag agacagagat tccgaatccg tatgtcatac atagaaaaca
    60901 catgtatttt atttaatttt tatttatttg caagttatga ggtgagcttt gctcttatct
    60961 tttctagaat ttgcttacta atggtaaaat aaaaataaga agaggaggga tgcgtatgga
    61021 acttgattat caagtagaag atgcgttgac gaaagtgttt tacggagaaa cgctagtcag
    61081 tcagctaaga gaactttcca ttgatcagcc aatcttattt ttaacgaatc agcgctatta
    61141 tgatttgttt gcagataaga tcaacccgtt atttgcaaat caagcaaaca atgactggta
    61201 tatttgtgcc aacactcaat gcaatcattt aacagaatta aagaacctgc ttgatttcgt
    61261 caaacgctat cccgaaaatc aatccatgtt tatcatcgga tttggaaatg aagggatcat
    61321 ggatctggca ggtttttttc aaaaacatac aacccttgat tcatcactat ggatgatccc
    61381 tgtatcgatc cgttctctaa gccgagcatt aacaccgcag cggacgattt tgcagctacc
    61441 aaatcgtgta gtgctgcaaa ccatcaatct gccagaacgc atcgtttatg atcaaacaat
    61501 cagcgagcgg caggtggacg gaaagcagat tgactttttg acttttatct gttgcggaat
    61561 gatttgtgat catcgttttt tgcaaaatct gtataaaaac tatccaaata aaaagcaatt
    61621 aacgactcgg ccgtttgccg ggatgatcga agaaatgatc tatttttatc aattagaggc
    61681 agaaaacctg tcaaattatg gtaaactgtt tgaacaagct ttttatctga ccgaaaatgg
    61741 ccatctactt tctgctagta tgaaaaaatt tttaggaatg atgtttcatt tcgtgtggaa
    61801 tctccaagca tatccttttg atttccaact aaaaaacttt tttgtgtggc tggacttgct
    61861 tggctatcca atccactggc tggaacagat ttcaaagatg gagtatttgg aaaaagttct
    61921 ttttttggca gaaaaaagca aaaaaatact tgttttagaa aaaataggta taatagacgg
    61981 ataccaacat ccaaacgaaa aagaattatt gagaacaatg acggtatttc aacaaatcgt
    62041 cagtgagata agagggaatt gaaatgaata caaatagcga aaaaatgttg caagctttat
    62101 cagatgaaga cttgtcacaa gcacaaatct ttttagaaaa agcattaaaa gaagacccag
    62161 cagatatatt agctgaacta ggcgaagaat tgctggctat tggctttttg atcgaagcaa
    62221 aacagatttt tgaacaactg atcaaccaat acccagaaaa tgacggactg aacatcccgt
    62281 tagcagaaat tgcaatcgaa gataatgaga tcgacttagc ttttgaatac ctggaaaaag
    62341 tggataagca aagtgattac tatccgcaaa gcttattggc gatagctgat ttgtaccaag
    62401 ttatcggaat ccctgaagtg agtgaagcaa aattgaaaga agcagctggg ttgcttcctg
    62461 atgaaccatt gatccagttt gcgctagctg aattgtattt ttcagttgat cgtttcaaag
    62521 aggcagcagt ggtttatgaa acattgttgg caagcgggat aaatgaaatt tcaggaatct
    62581 cgatgcagga acgtttagga caatccttaa gtatgcaagg agaattcgaa gcagctatcg
    62641 tacctttaga agaagcactg aaagaagaaa ggacagatga tcgactgttc cagctagctt
    62701 ttacgaatct tcaattgaaa gaaaatcagc aggcaatcaa ctatctggaa gaacttcgag
    62761 aagttaatcc gcattatcaa tcgttatatc tatatctagg acaagctctt caagaagaag
    62821 aaatgattga agaagcacaa acagtgttag aagaaggaat caaagaaaat ccttaccaag
    62881 tcgaacttta tcacctggcc tcggaaaatg ctttccgtct gcatgataga cagcgagcag
    62941 aagaactttt actgaaagct ttagaagtag gagacaaaca agatgaaaca ttacttactt
    63001 taagtaatct ttacttggat gatgaaagat atgaagatgt gatacaagtg atcaatcaga
    63061 tggaagaaac tgctaatcct tatgcagaat ggaacctagc ccatgcttat aatgaattag
    63121 aagactttac cgttgcagct gtacactatg aacaggctta tcatgaacta tcacatgaac
    63181 cagatttctt gaaagagtat gcctttttct taagagaaga agggcagctg aaaagagcgc
    63241 aagaattatt gacttattat ttaacacttg aaccaggaga tatggaggca ctgtcattat
    63301 tagatgacct aacagagagg tgagaaaaat gctaattgat gtacgggaaa agaagaattt
    63361 tttaacgtgg atggtcaatc atgtatcttt tagccgaaga gaagtttttt ggatcttgaa
    63421 ttatcttgcc aatcatgaag cgattttaag caatgtccac tttgttgaag gggcgaattt
    63481 tgcggatcga ggactgcaga tcagtgatct atctgttgaa ggggaaccca tgaaattgtt
    63541 tttgcaggga aaagaattta cggacacaga ccagattttt catgaaatcc gtttgaattg
    63601 gaaaaagcct ttatatgtgg aatgtatatt cgaaaatgct tggcagacaa gagaatatct
    63661 atctatctta gaagacaatc cattttcttc ttgggattct tcagtcagtg aagaagatac
    63721 tgaattaatt gaacgatatt ttcaagaaaa agaagaagag gcaaaactaa aaatgcttta
    63781 tgctcaaatc gatcaagcac tagaagatgg agatagggat gcttttttga aattatctga
    63841 tgaagttaac cgaaagatcc ttttgcagac acaaaagaaa agtaaccggg taagtgaaca
    63901 taacaattag ttaaaaatag tatagtacta aaaaagacaa aggtcagctg gatgtggaat
    63961 ctttcctcat agcctatctt tgtctttttt cttatagttt tttcagtaat cttgtctgtg
    64021 gcttcaaata agtaaagcct tgcccttcca cttcatgcac attgatgatt gaaaggaaag
    64081 ctttttcgtc aatctcgtgg acgatcctct tagcttcagt taattcacta gagctaacga
    64141 ccatatagat gatttttttt gaattaccag agaatgcgcc ttctccagaa aggaaagtca
    64201 cacctctttg cagaccggtc atcagtagtg gtgcaatctc ttcgcttttg ttggagacga
    64261 caagtagacc ttttgcagaa tatccgccat ctaagatcga atcaatcaca cgactgaaaa
    64321 catacgaaac aatcaacgta tacatcatac gtttcaagtc gatataggtt aatgaagcaa
    64381 gtaagacgat gatatcaaat gccaataggg aacgccccat agtgatgccg taattttgtt
    64441 ctaaaatccg agcgataata tcactgccgc ctgttgttcc acccatgcgg tagacgatcc
    64501 cgcttcctac acctgcaact aaacccgcaa gtagagaaac gatcagtaga tcatgctgta
    64561 aattgatttc tagtggaacc ctttgccaga tccataaaaa gaatgacaaa gaaagtgtac
    64621 ctagaacagt ataggccaag gaacgtttac cgaggatctt tcctcctagt aaaatcaatg
    64681 ggatgttgat taataaagtc gtataagctg gatcaatacc aaataaagct cttaagatca
    64741 aggtgatccc tgagactccc ccttctgcta aatgattagc gatgttcaag taaacaagac
    64801 caaatgcata aatacttgtt cctataatga taaaaagaac ttcttttact gtttttcgtt
    64861 tgaccatatg aattccagct ttcaattatg tattttcaca gaatttccat ttagaaattc
    64921 cttcctaaat gtagcatgga aattcgattt tctcaattgc tcttatctag gatttgcgtt
    64981 aaagttttgg taagatagtt ttggagggaa aaagatggat aaaaagcgtt ctttatacag
    65041 tatgcagcag gaagtggatg aatatatcca gcaattcaag gtggggtatt tctctccatt
    65101 agctcagatg gctcgattaa ctgaagaagt aggtgaattg gcaagagaag tcaaccacac
    65161 ttatggagaa aaaagcaaaa aggcttctga accagttaac tcggtagcag aagaacttgg
    65221 tgatgtttta ttcgttacga tgatcatggc taattcattg aatatcgact taactgaagt
    65281 ttttgaaaaa aacatggaaa aattcaatca aagagaccat aatcgctttg agcgtaagga
    65341 cgagtaaaca agatgaagtg gtcctggcct tgaagactct gaaacggact tgtcaaacag
    65401 tcaccatgca actgagtctt tatctcagga caagaaacac gcaggaaagg ttggaaaaat
    65461 gaaattaaaa caattacctc tggaatacca aaaggcaatt ccagttctga aaaaattaga
    65521 gaatgcagga tatgaagctt attttgtagg tggaagtgtt cgtgatatct tgctgaacca
    65581 gccaatccat gatgtggata tcgcaacaag cgcatttcca gaagaaatca aacagctttt
    65641 tccaaaaacg atagatattg ggatcgaaca tggaactgtg ttggtattag aaaatgatga
    65701 acaatatgag atcaccacat ttcggacgga atcaacttat caggactacc gtagaccaga
    65761 tcatgtcgaa ttcgttcgtt cgttggcaga agatttgaaa agaagagatt ttacgatcaa
    65821 tgcgtttgct ttgaaagaag atggagaaat catcgatttg ttcgatggtc tgcaagatct
    65881 agaagaacag atcttgcgag ctgtaggcaa tcctcatgag cggttccatg aagatgcctt
    65941 acgaatgatg cgcgggttgc gttttgtcag tcaactaggg ttcaaattag aggaagaaac
    66001 cttctacgcc atcaaagaaa accacgagct attaggtaaa atatctgtag aacgtataaa
    66061 tgtggaattc atcaagatgc tcttgggaaa tgaacgggcc gcgggaatcc atgcatttat
    66121 tgaaacagag tgctacattt gctgtcccgg tttgaaagaa gaaggcgaag cacttttacg
    66181 ttttgctgaa ttaccatccg tcccattgaa agaagagagc caagcatggg cattattgat
    66241 cagccaactg gatctaaaag aaaatgagat tcgttccttt ttgaaatcgt ggaagtgttc
    66301 taaccaaatg attaaagacg ttcaagcact tgtccaagga ctacgacaac gagaaactgg
    66361 agctttggaa ccattcgaat tgtacttctt aggcaaaaaa catgcactgc aagtagaaga
    66421 attgatgatc tattttgacg aaacacctca gatggatgcc gtaggagaat cctatgatcg
    66481 tttacctatc aagtcattaa gcgaattagc agtagatggt aaaatcttgc tagaagaaac
    66541 tggaaaaaaa cctggtaagt gggttagtga agctttgcaa ttagctgaaa aagccgtcgt
    66601 agaacaaaga ataaaaaatg ataaaaaaca ggttttggat tttttatcga aagaaaaatt
    66661 gatttaaaaa acactagact gtatctgctc agctttgttg gctacttaaa gtgggcagat
    66721 acgtcattag aagaaaaaac ataagatgtg accacttaca taaatttgtg ctaaactgag
    66781 gtagtacaag aataaattac atcataaagg agtcttttta atgagtaaag aaatgacagc
    66841 gctaaaattt tattttagaa atggagaaac ctggacgatc aaccgccgtc atatcggcga
    66901 tctttggatc aaacaaatca caacaagttt tggacgaatc aatggcagtg aatttgttga
    66961 aatccatccg tgtgctggat ttaaaatcga aatcttccat gaaggggacg cagttgcgac
    67021 acatgatatc aacctaggcg gactggaaat gggcatgttt aatcgcgcat tgaaatacga
    67081 agatatcgag cgaatggaaa tcctttaccg aaatggcaca cctgatcttg tgtacttccc
    67141 atatctagat aaaggaacag aaggattaga caatcaatat caatcaacaa aaatcaggga
    67201 aaaacaggta acttgtatat cgtgatcaat ccagatcaac gtgtagaaga tgtatacggg
    67261 gaatttttcg aataaatcga tttttacgca aaaatgaggc tgtgaaagag atgtgtctta
    67321 ttactactga taggctgtct cttccacacc gtttattcag aataagggac tgtgacaaga
    67381 tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca ggaatgggaa
    67441 agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga tatctgatac
    67501 tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag caataaacga
    67561 tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg aagtttgtgt
    67621 ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt tgcatgatcg
    67681 ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc gtaaaagaaa
    67741 tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt tggagtcaaa
    67801 acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg aaaccaaaat
    67861 tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat aaaggggatg
    67921 gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct tatcgaacat
    67981 agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc ttggagtggt
    68041 attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt tcttagttat
    68101 gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt cgattctcaa
    68161 aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc ttgtcggggt
    68221 aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct ttgcttttgg
    68281 agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac gagtgaatat
    68341 ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg catctggtgt
    68401 tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag cagtaaacgc
    68461 ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt tgcttgtctg
    68521 gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg tcacagggta
    68581 tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg catttgatgt
    68641 atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt ttaggaaaat
    68701 ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa ctattgcttt
    68761 tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag tgttctcgcc
    68821 agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg tattaatctc
    68881 tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat tcaaagatgg
    68941 cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg gcggtgtaaa
    69001 gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata atatgatgtt
    69061 ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga ctttggtcat
    69121 agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca cggatttgaa
    69181 tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa aggaaattga
    69241 tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc aagaacggat
    69301 acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac aagaaataca
    69361 agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt cgggcaagct
    69421 ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac attctatcac
    69481 aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt taatgcgaat
    69541 cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga catttattag
    69601 tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt tgattattga
    69661 aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt ttatccagca
    69721 acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt ggatgatcca
    69781 gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat
    69841 tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct atcgcaggaa
    69901 tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt ctttccgatt
    69961 tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta aaaattttca
    70021 agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt ctttttttga
    70081 gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt ttatgataca
    70141 atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc tcaaaaaaac
    70201 ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa aagaccgtat
    70261 cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta ttgccggtat
    70321 cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc gtattggtta
    70381 tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag tctttcaagg
    70441 aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg aactagggga
    70501 aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac aaatgaataa
    70561 agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat taggaatcag
    70621 tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag ttagtctggc
    70681 gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa accatttaga
    70741 ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg cactattgat
    70801 ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg aactttcatt
    70861 tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa aagcagaacg
    70921 tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac aggaattagc
    70981 ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga tcaaccgttt
    71041 cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag agctgaacct
    71101 agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt accgtataaa
    71161 tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa gactaggtat
    71221 tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg gcagaattcc
    71281 cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt atacacaaga
    71341 aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag ctgctgaaga
    71401 agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac gatttttatt
    71461 tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa aacgccggtt
    71521 atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg aaccgaccaa
    71581 tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt ttccaggtgc
    71641 tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata agttattagt
    71701 attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt atttactgaa
    71761 gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga gcaaggaacc
    71821 tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga ttgaagatga
    71881 gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc atcaaggaga
    71941 taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag cacaacttga
    72001 agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg aggaaaaagg
    72061 atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca tcgtaaagaa
    72121 gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt tgatctgcaa
    72181 aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa aagcgaattg
    72241 ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa aaaccatatt
    72301 tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg accagatatg
    72361 actgattttg gccatagatg tttgacagat cctgaattca atgaagaata taaaaagcag
    72421 agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac atacggcgat
    72481 cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg tggctttatc
    72541 gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag aagattgatc
    72601 gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg tcatacgatg
    72661 tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg cagtggggat
    72721 gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca cctaattgca
    72781 catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc tcatctttat
    72841 atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc atttccgact
    72901 ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga tatccaatta
    72961 gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa tcagaaagga
    73021 tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg gaaaagaaga
    73081 ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga cagaagcaaa
    73141 tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt tgccgaatcg
    73201 tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc atgtcatgca
    73261 tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt tcatcgctgg
    73321 agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc gtacagtcat
    73381 ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg attggtcact
    73441 gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc aatttgaaac
    73501 gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga tataaaaaag
    73561 ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt ttttttatta
    73621 agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa acaaatgcca
    73681 aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta tcgtgtaaga
    73741 aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat aaagaggaac
    73801 agcagccacg acacagagcc accccataaa aatatagatg atcgtagata cttttgatac
    73861 tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg caaacaacca
    73921 gattaataca aataaagtcc aacctagcca tcctcggata ctcagcaaac aaaaaggagt
    73981 ataacttcct gcaatcaaaa gaaaaatcga actatgatcg aatacttgga acaccttttt
    74041 tgcttttgta aaaatcaatg aatgaaacaa agtagacgtt aaaaataaaa gaatcatcat
    74101 cgatccatag atagcataag agacaatatg gagggaggaa tgcaagtggg caccttttac
    74161 taaaagaacc actagtcccg cgatactcaa tccagtccca attccatggg tgactgcatt
    74221 aaacacttca tttaatattt catacgttcg attaaatttc gttttttcca tgaaaacggc
    74281 tcctttacta ggtgtaatta atgaaaaatc attatttgtc tgttatacta aaaatagaaa
    74341 ttgtcttaca tgtagtttaa catgaataag gcatcttgtt aaagaaagag agagagaaaa
    74401 taatgacaaa tgtaaaaatc gtaacagatt cttcatgtac gatggaaaaa aatgtacgcg
    74461 atgctttagg cattcgtgtc atgccgctat ccatcatgat cgacggaaca gtatatcccg
    74521 atgatgacca actagacggc gaaagattta tggaaatgat ggcgaaagca aaaaatctgc
    74581 ccaaaacaag ccaaccacca attggagaat tcatctcgat gtatgatgag ctaggagaag
    74641 acggcagtga agtgatttcg atccatatga caaaaggctt gagtggaaca gtagaagcag
    74701 caagacaagc cagtaatcta acaaaaacga aagtaacggt tatcgacagt gataccactg
    74761 accaaggatt atcttttcag gtaattcgag cagctgaatt agcaaaagaa ggtaaaacag
    74821 tagagaaaat ccttgaagaa gtcaaaaaag tacaagacaa tacaaaatta tacatcggaa
    74881 tatccacact agataacttg gtaaaaggtg gaagaatcag ccgaacaact ggtttgctgt
    74941 ctagtgtttt gaacatacgc gtggtgatga atttcgccca ttctgaatta atccctgtaa
    75001 ctaaggggcg aggaaagaaa acgttcgata aatggtttaa taatttgaaa aatgaactga
    75061 aagaattgcc aaatgtgcga caaatcggta tttcacatgc ggatgcaaaa gaattggcgc
    75121 aagaattcaa agagggtttg caagaattat tcccggacat gcatatccct gtactgcata
    75181 cgaatccggt tatcgctacg catactggta aagacgcgtt tgcaatcatg tattatgtag
    75241 attagtcgaa aagaggataa gccctcagcc tgaaaggctt gcagcttatt ctctttttct
    75301 ttataaaatt aggaaaataa ttgttttctt ttttcataaa gactaccttt ttgataaaat
    75361 ttttgataac attagaacca atcgaataca agaggtgaaa aaatgaaatt aacgaaacga
    75421 catttgatcc tcgttttgtt cccattatta attgcgatca tcatctatgc aggtttagct
    75481 gcttctatac cgaaagctgg cccactaatg aaaccagtaa ctactgtgag agaagatcca
    75541 aataaaaaag aaaaacttca ctacatagct atcggagatt cgctgactga aggagtagga
    75601 gatcaaacca agcaaggagg attcgttccc cttgtcgcaa atgatctaaa agaccgttat
    75661 aatttgaccg cggttgaaac agaaaactat ggtgtaaatg gtgaacgaag tgaccagatc
    75721 ttaaagcgag taaaaacaaa agaagaaatt cgaaacaata tcaaaacagc tgattttatc
    75781 acactgactg ttggcggtaa tgatttgatg aaagttatcc aaaataattt attcgggtta
    75841 acggtcaatt cctttaaaaa gccactgaaa aactatcagg aaaatgtcac agaactattg
    75901 gaagaatttc gatccctcaa taaaaccgca cctatttaca ttttaggcat ctacaatcca
    75961 ttttatttga actttcctga gatcactgac atgcagacaa ttgttaacaa ttggaacaaa
    76021 ggaacagaaa cggtgacaaa aaaaatgccg aactgctact ttatcccaat caatgatttg
    76081 ctttatcaag gattgaatca ggaagtaggt gtcacagaag aaggaacaga tcaaacaact
    76141 agcacgacag aaaatctaaa tggcatcaaa aataatgtgc tctatgaaga agatcatttc
    76201 catccaaata atttaggtta tcaattgatg gcaaatgcag tgagagatca gctgatcgag
    76261 acacaaaacc aatggttaga gaaggaggat gatcaataaa catgaaaaca agatctgacg
    76321 tatcttcaaa caaaacaaag aaaacaaatt actggaaatt cgccttcctt atccttcttg
    76381 gggtagtact tggttcgacc gtatttttag gcagccgtat ttttgctaat cgggaaccag
    76441 aactcccaga aataccagct cttacggaaa gacaaggaga tcctgtctta acgatcaatt
    76501 caaataaaga aaaagtcaat caaatcatca gctttttcct tagtgagtat caaaaagata
    76561 gtgatattga atataaattt tatttggaaa atgaagcact actcaatggt actttcgaag
    76621 tactaggttt tcctatcgat ttctatttat attttgatcc gtatgtgatg gaaaacggaa
    76681 atgtccaact aaaagctaga agtctttcta tcggaacatt gagtttgcca atcaaagatg
    76741 tgatgaatat gatcaagaga aactataaat taccagattg gatcgaagtc aatacagatg
    76801 atctgactat catgcttagg ttggatcaat tccgaatgca aaacgggatg tatattaaag
    76861 cagataaaat cgacttagta aatgatgaca ttcggtttag tctatatttg ccaaaagata
    76921 cctctgatgc ttcaaacaac tcaaatacca acaaaactag caccagcagt actgaaagca
    76981 agacaaaaga aaataaaaaa tcatcggatg agtagtatta gagggggaat cataatggaa
    77041 cgagcaatat ttgcaggagg ctgcttctgg tgtatgatcc agcctttcga cacgcttcct
    77101 ggtatccata cagtgatgtc aggatatact ggagggcatg taccagatcc gacttatgaa
    77161 caagtaaaaa gccaaacgac tggacataca gaagcagtgg agattatcta tgatccaaca
    77221 ttgatttcat atgaacaatt agtagaactt tactggcagc aaactgatcc aactgacgct
    77281 ttcggacaat tcgaggatcg cggtgacaat tatcgcccgg tgatctttta tttgacagaa
    77341 gaacagcgga tcattgctga aaaaagtaag aaacagttag ctgaaagtgg acgtttcgaa
    77401 cagccaatcg ttacaaaaat cgaaccagcc caaccatttt atctagcaga agaagaccat
    77461 caagagtatt ataaaaagca tcctgaaaat tttaaaagaa accatgcacg ccgggctgcc
    77521 tttatcgaag aaaattggag gaacgaaggg tgaatcgaag cttttttcat tatttaatga
    77581 cactgcgagg cggtggcaca catgatgctt tatctgtttt cgctacagaa gccggtaaag
    77641 acatccaatt tcctaagcac agctctagct acgaagaaat ttctaattat ctggaactga
    77701 atgtcgacta tttgccgtcc atggatatct ttgacgaagc atgggaaaaa tatttagaaa
    77761 ataatcatga catataagag atagttttgt actttatgat caaaaaagtt ttttgtccaa
    77821 tagcctaatt gaaagaatta tttttatttc agctatctag tcgcattttt ttgatatttt
    77881 tcttataata aagaaagaat gaaaaaaaga gggatggatt gatagagatt gacaaaaaaa
    77941 caacgctata ttaatcgctt ctggcttgta ttcaaatact tacttgtttc tgtattcctt
    78001 gcgttcatgt tgcggggatt tttattcatc ccggtaccag tggaaggcaa ttcaatggaa
    78061 aacgtgttga agcaaggtga tatggttgtg atggaaaaat tttcggagat cagacgattt
    78121 gatattgttg tttttcaatt agcagatggc acgatttata tcaaacgagt aatcggtctt
    78181 ccaggagaaa atgtcagcta ccaaaatgat caattgaaga tcaatgggaa agtagttaag
    78241 gaaccttatc taactaaaaa cctgaaatca gatcatgcaa atgcatccta tacgacggac
    78301 tttacactac aagagctaac gggacaatcc aagcttccgg aagataatta ttttgtactt
    78361 ggagataatc gaagagtttc aaaagatagt cgttcgtttg gcacgatcaa taaaactgat
    78421 attctaggta aagcaagatt tgtctattat ccacttgatg aaataaaatg gatccagtga
    78481 gaaacaataa agcgtgcagt ctgttgagac tgcacgcttt attgtttaat ccaaaatcag
    78541 tttactacct tagtacgtaa aatcaaacag ctcgtttaaa cacttttcta gcctctaaag
    78601 ttttgataaa tgaataaaca accattattt gaatagggat ttggatcata ttcctgatga
    78661 atctacctag aaaaattact ttgaaatctg caccaaacaa aacagacatc agccaagaat
    78721 tgataaaaag gctgactggg atcataatca ataattgggc agcgatgacg gaaggcaggt
    78781 ttatcttttt atgatataaa aataagccat taataaatcc accaaggaaa gccgtgataa
    78841 gaaaagcagc ttgaaacgtt cctgaaccaa atatcgtgaa atttaaagtg ttcgacaaca
    78901 tttcaagcaa accagcccag atcggtccat atagataacc cataagcgcc atacttaaaa
    78961 atccgaatgt gatttgaaaa taagcaggac caatcgctat cttgtataag atgacatcaa
    79021 gggctaataa aagagcagag gtcgacaaca atcttgcatt catttcgggc aatctaaaaa
    79081 cgtcttttgc aatcaaagtg ttcaaaatat tctctccttt gtcagttaat aataaaagga
    79141 taccataaaa tcaccaatgt gtcatgacac attggtgatt tacatacact ggcatctaac
    79201 aattaaaaaa agggtgagaa gactgctttt ataaactgta aaaaagagat tgtacgaata
    79261 aaaaaaatag aggcggagaa tacttatcgt atcatccgcc tttgtttttt tgttataaaa
    79321 aacgtcagat tagttatctg cttacatctt catccatacg ggttctaatg tatttccgtc
    79381 tagatcttgg acttctaatg aaaacatttc ttcttcaggc attcccatat ctacttcgtg
    79441 gaaagtacca ccattttctt ttgcaatttg agcaaatttt tttacttcat ccgcattttc
    79501 aacactaaac gaaatcaaag caccacttgt ttttttatta tcagctattt ctttatcttt
    79561 tataaatttt ttataaaaat catgagagag aagcattatc caaaaagtgt catcccatac
    79621 cattgaacca gcttcttcag tagaaaattc ttcatttttt ttaaaaccca gcttttcata
    79681 aaaagcaacg gaacgattga catcagcaac aggaaaatta acaaaaacca tactattcat
    79741 ttgtttcgtc tcctttctgt tttgttcgtc tatcatctct tatttaggaa acgctgtcaa
    79801 aaatttagat tcatatatag aaaccaaaat aaaaatttgc atcatcaaaa aagtgaagat
    79861 gtgatagaat gaggactggt tcactttcac ttaactaata gatggaattt ctttataata
    79921 aaaaagtgaa tttatattga aaaagaaaaa aacaagtaaa gccggggaat attccggtat
    79981 gaaaggaatg gagagaacaa tgaccatcca atggtttccg ggacatatgg caaaagcccg
    80041 acgagaagtt tctgaaaaaa tgaaatatgt ggacatcgta tttgaattgg tagacgcacg
    80101 attaccttta tcttctcgta atccaatgct agatcagatc attcagcaaa aacctcgcct
    80161 tgttttattg aataaagcgg atctggcaga tccacaacag acaaagctgt ggcaagaata
    80221 ttttcgtaaa caaggccatc ttgcattagc tatcacggca caagaaagta aaggaattaa
    80281 aggtctagta cctgcggcta aagaagcatt gaaagaaaaa cgggcaagag atgctgctcg
    80341 ggggatcaag cctcgcgcta ttcgggcaat ggtcttaggt attccaaatg ttgggaaatc
    80401 tacgttgatg aatcgactag taggcaagaa aattgcacag acaggaaata agcctggcgt
    80461 aacaaaaggt cagcagtggc ttcgtttagg taatgagttg gaattgttag acacaccagg
    80521 gattttatgg cccaaatttg aagatgaaga aatcggcaaa aaactagcgc tgacaggcgc
    80581 gatcaaagac cagcttgtcc atttagatga tttagcgatt tacggattag acttttttgc
    80641 ccgatattat tcaggaagaa tcagcgatcg ttatggttta tcaatcgagc aagaagaaaa
    80701 attggcaccg gaattactga tggatattac agcaaaacgt gggtataaag aagactatga
    80761 tcgtggcagc gaattagtcg tgcatgatat tcgtcaagga aaacttggac gatacacact
    80821 ggatcgttgc gaagaaatgg agcaaaaaag tgatgactga atccatccaa agtatcaaag
    80881 aacgattgaa aagcatacag agaatagatg atcctacact agaatcatta agaaatgatc
    80941 cacgcaaagg cgtgcagcaa gcactggctt cttttgaacg acgattgaaa aaggaagcat
    81001 taattaagga aaaatatgaa gaaatgtttt gctttgaaaa gcaagggtac gcacaaggtc
    81061 accaatggat tgccggcatt gatgaagtag gaagaggacc attagctgga cctgtcgtgg
    81121 cagctgcagt tatcttgccg aaaaatgaga tcatattagg gctgaatgac tccaaacaat
    81181 tatcagagaa aaagcgagaa cttctttatc aacaagttca agaaaaagcc ctggcaatcg
    81241 ggatcgggat cgttgatcag cagacaatcg atgatgtgaa tatttatgaa gcaagtaaat
    81301 tagcgatgat ccaagcagta gaaaaattgt ccattgtacc aagctatttg ttgatcgatg
    81361 cgatgacctt ggatttgcct attcagcagg aaaaaataat caaaggggat gcacgatctg
    81421 tgtcgattgc tgctgcaagt atcattgcta aagtatatcg agaccaattg atgaaagaat
    81481 atgacgtgct ttatcctgga tatggtttct cgcataatgc aggttatgga acaaaggaac
    81541 acttagaagg acttgaacga caaggaatta cgccaatcca tcgtaaaagt tttgcacctg
    81601 taaaaaaata tttacaataa aaaacagccg cttttacgta tcttattaga aagagagacg
    81661 aaaggcggtt ttatgatgta tcaaatagaa gaaaatttat tgaaacttgc ttatacaaaa
    81721 ggaatcagta gtcaaggaaa atgggcactt gctaactgga tgatgcagta tccttataaa
    81781 gaaatcggat ttgaagacat cattaagata ggtaaaataa ccaaacaccg ggagctgttt
    81841 cgcaaaagtt ggcaggaaat tcacgctaac tggggcaaaa tccaatcgaa acagtcgttt
    81901 atcacttgct ttgatcccaa atatccccct cagctgcttc acttgaccta tccgccaatt
    81961 gtactgtttt ataatggtga tctatcttta ctttcttgta acatgttaag cgttgttggt
    82021 ggaagacaca cttctgcttt agccaaaaaa acagtttatt atttactaaa accagtgata
    82081 gaagctggat atgtgatcgt cagtggctgc gcgaaaggga tagatacata cggtcaccaa
    82141 gcagcaatct ctcatggtgg acggacaatc gcagtcattg gaacagggat agagcaagtc
    82201 tatcctgctg aaaatcgtga cttgcaagag gtgattgcaa atgatcatct tcttttgagt
    82261 gaatatcctc ctcaatccgg cccgaaaaag cattgttttc caatgagaaa tcggattatc
    82321 gcagctttgt ctaaaggaac atgtgtcttt gaagccaaga aaaaaagcgg ctctctgata
    82381 acagcacagc aagcattgga tcttggaaga acagtttttt ctgttccagg aaatatttta
    82441 acagaacatt ctaccggatg tcatcatttg atccaagacg gtgcagtttg cacggtttcg
    82501 ggtgaagata tcttggcaga atttaaagaa taacaccata cttttcattt gcttttcttg
    82561 acaaacgttt tctgaatgga tatgattagc tacgatttgt atgaatcctc ttttaatagt
    82621 aggaacacga caatggaaag gagtccattc agtaatggcg tataaatatt tagtgattgt
    82681 agaatcacct gcaaaagcca agacaattga gaaatatctt ggacgaaact ataaagtaat
    82741 ggccagtgtt ggccatataa gagatttacc gaaaagtaaa atgggtatcg attttgaaaa
    82801 caattatgaa ccccattata tttctatacg cggaaaaggc gatgtcatca aaagcctgaa
    82861 agccgcagca aaaaaagctc aaaaagttta cttggcaagt gacccggata gagaaggaga
    82921 agcgattgct tggcatttag cgtacctact tgggttggat ctgaaagaaa aaaatcgggt
    82981 ggtcttcaat gaaatcacaa aagacgcagt caaagcagct tttaaggaac caagaacgat
    83041 cgatgtagat ttagtagatg cacagcaagc tcgtcgtacc ttagacagaa tcgttggtta
    83101 ttcgatcagt cctattctct ggcgtaaggt caagaaaggg ttaagtgcag gacgtgtcca
    83161 atctgtcgct ttaaaaatta ttattgaccg tgaaaaagag atccgagaat ttgttccaga
    83221 agaatattgg agcatcgacg gtaattttaa aaaagctcgc aagaaattca aagcaaattt
    83281 ctggggaatc gacggtaaga aaaagaaatt accagatgca caaagtgtaa aagaagtcac
    83341 tgctagaatt gatggaacag acttcgaagt taaaaaagta gaaaagaaag agcgcaaaag
    83401 aaaccctgcg aatcctttca ctacaagtag cctgcaacaa gaagctgccc gtaagttaaa
    83461 ctttcgaaca agaaaaacca tgatggtagc acagcaatta tatgaaggaa tcactttggg
    83521 taaacaagga acagtcggct tgattacata catgcgtact gattctaccc ggattgccga
    83581 tacagcaaaa gcagaggccg cagcatttat tgaagatacg tatggaaaag aattttctag
    83641 acatgatcac cgaaagatca aaaatgctca aggcgcacaa gatgcccatg aagctgtgcg
    83701 tccaacgagt gtgcttcgta caccagatga actcaaacaa tatttagata aagatcaatt
    83761 gaaactttat acattgatct ggtcacgttt tgtggctagt cagatgacac cagctatttt
    83821 agatacaatg aaagtgacat tagaacaaaa tggtgtcatc ttcattgcga acggttcaaa
    83881 aatcaaattc aaaggattca tgcaagtgta tgtggaaggt agagatgacg gcaaagaaga
    83941 gaaagaaaat attcttccag aacttgaaga aggcgatgta gtccaatctg ttgatattga
    84001 accaaaacaa cattttactc aaccaccagc acgttttagt gaggctacgt tgattcgtgc
    84061 actagaagaa aacggggtag ggcgaccttc cacttatgca ccaacacttg atacgatcca
    84121 aagacgctac tatgtaaaat tgacacaaaa aagatttgag ccgactgaac taggagaaat
    84181 tgtcaattca ttaatctgtg aattcttccc tcaaatcgtc gatatccatt tcacagcaga
    84241 aatggaagga gatttggata aaattgaaga aggcacggaa gcgtgggtca aagtggttga
    84301 tcgtttctat aaaccgtttg aaaaagaact gacgaatgcg gaagaaaaaa tcgaaaaaat
    84361 tcaaatcaaa gatgaaccag caggattcga ttgtgatgtc tgtggacatc cgatggtgat
    84421 aaaattaggg aaatatggga agttttatgc ttgcagtaat tttcctgatt gtcggaatac
    84481 gaaaccaatc gtaaaagaaa tcggtgtgac ttgcccagta tgtcatgaag gacaagtcat
    84541 tgaacgaaaa tctaagaaaa acagactatt ctatggttgt tcccgtttcc cagaatgtga
    84601 attcacttct tgggataaac cagtgggcag aaattgtcca aaatgtgacg gatatctggt
    84661 cgagaagaaa gtcaaaggcg gtaaacaagt agtctgtgta aatggagatt acgaagaaga
    84721 catccaaaaa taatagaaaa gaggttcttt cattgaaaat ggtaaatgtt gttggagcag
    84781 ggcttgccgg aagtgaagct gcttggcaga tcgcacaagc aggagtccct gtccgtttat
    84841 atgaaatgcg tccagtcaaa tcgactgagg cgcatcacac aagtaatttt gctgaactag
    84901 tatgttccaa ttcattaaga ggaaacagtt tggctaatgc agtagggtta ttgaaagaag
    84961 aaatgcgccg attgaattcg gtagtaatca cttcggcaga tgaaacagca gtgccagctg
    85021 gtggtgcctt agctgttgac cgcgattctt tttctgaaac aattacccga aaagtcaaag
    85081 agcatccatt agtaacagtg ataaacgaag aaattactga aataccggaa ggaatcaccg
    85141 tagtagcaac aggacctttg acttctcatc cattagcaga aagcatcaaa gcattcaatg
    85201 gttcagatgg tttttatttc tatgatgcag ctgcaccaat cgtagacaaa gctacgatcg
    85261 atatggataa agtatatttg aagtcccgct atgacaaagg agaagcagct tacttgaact
    85321 gtccgatgac agaagaggaa ttcaaagctt tccatgaggc actaatcaat gccgaagtgg
    85381 cagaacttaa atcttttgag aaagaaaaat attttgaagg atgtatgcca attgaagtaa
    85441 tggcacagcg aggattcaaa acgatgcttt tcggacctat gaaaccagtt ggattggaag
    85501 atcctaaaac tggcaaacgt ccttatgctg ttatccagct gcgtcaagac aatgctgcag
    85561 cttctttata caacatcgtg ggctttcaga ctcacttgaa atggggcgag caaaaacgtg
    85621 ttttccggat gattcctggg ttagaaaatg ctgaattcgt tcgctatggt gtgatgcacc
    85681 gaaacagctt tatgaattcg ccagaattgc tgaaaccgac ttaccaatca acgaaacgcg
    85741 aagatctgtt ctttgcaggt cagatgactg gtgtagaagg ctatgttgaa agtgcagcga
    85801 gcggactact tgctggaatc aacgccgcac gcttagcaaa agaaatggaa ccagtcgagt
    85861 ttccacaaga aacagctatt ggaagtatgg cttactacat tactcatgcg gaaggaaaac
    85921 atttccaacc gatgaatgcc aactatggtc tgtttcctga actgccagag cgcattcgag
    85981 acaaaaaagc aagatatgaa gcaattgcac aacgagcttt aaaagctaat gaggcaataa
    86041 aaacagaatt agaaaaaact gcaatcccaa atgagtaagg aaactccatg aagagggtga
    86101 gacggatagt ctcgctcttt ttcttgcgtt tttcttaaga atttctcaaa caaaatgtga
    86161 ggaattgcgc caattgtgaa caaacttaga aatattggtt aaattctgac aatttatttg
    86221 tctttttata aacgctgtgc taaattattc tctgggacaa aaggaaggtg agaaaatgac
    86281 agaagccacg tgggaacaaa aatttttgcg ttatttgatt gtcgaaagag gatattcaga
    86341 aaaaacgaaa gaagcatatg aagaagacat tctccatttc aaacattttt tggaggaatc
    86401 tggagacgct gatctgctga aggcggaata ttttacggtt cgtgtctatt tgagtgcatt
    86461 agctgatcat cgtcctagct atagcagaaa ttctatcagt cgcaagatag ccagcctacg
    86521 ttcgttttat cagtatcttc tcaaagaaga agtgataaaa gaaaatccat tttcttacgt
    86581 tcatctcaaa aagaaaaatt tgagactgcc acgttttttt tatgaaaatg aaatgcaagc
    86641 actttttgac agcgtagcag gagatagtcc tttggatttg aggaaccgcg ctttactgga
    86701 agtcctttac gggtcaggca tccgtttaag tgagtgtagc agtttgtcgg tatcagacat
    86761 tgattttgat tcagaggtca tgttgatcca tggtaaaggg aacaaagaga gatatgctcc
    86821 tctaggttct tttgctcaag atgctctgca agaatatttc agggaaggcc gccaggtatt
    86881 gatgacaaaa tatcacgaag agcatgatat cgtttttgtg aatcatcatg gaaaaccaat
    86941 cacgcctact ggaattgaat atgtcttgaa tcaaatgatc aaaaaaagca gtttggatag
    87001 tgatatccat cctcacatgc tgcgccatac atttgctact catttattaa ataatggggc
    87061 agatttgcgg acagtccaag aattgctagg acatgccaat ttatcgacta cccagatcta
    87121 tgcccatgta acaaaagaaa gtttacaaaa aaactatcgt tctttccatc caagagcgta
    87181 aaaataagga aaagaacaaa tttaggagga aacaaacatg gtcgaatcac catttcattc
    87241 aaccactatc tgtgccgtcg aaaaagacgg gaaatttgct atggctggag atggccaagt
    87301 aacaatgggt gaatctgttg tcatgaaagg cactgcaaag aaagtacgac gtatctacaa
    87361 tggagaagtt gttgtaggtt tcgccggaag tgttgcagat gcgtttactt tagaagaaaa
    87421 atttgaaggc aaactaaacg aatataacgg gaatctacaa cgcgcagctg tcgaattagc
    87481 tcaagaatgg cggacacagc aatctatgca aaaacttgaa gcgatgctga tcgtaatgaa
    87541 tgataaagaa atgcttcttg tttcaggtac aggagaagtt atcacaccag atgatggtat
    87601 cttagctatc ggatcaggag ggaattttgc gttggctgca gcccgagcaa tgaaaaacta
    87661 tgctcaaaac gacatgagtg cgaaagaaat tgcagaaaat gcgttaaata ttgccgcaga
    87721 tatctgtatc tttactaatc ataatattat cgtagaagaa ctgtaagagg tgagtagata
    87781 tgtatgaatt aaaacaaaca ccaagacaaa tcgtaagtga attagatgaa tatatcgtag
    87841 gacagcacgc agcaaaaaaa tctgttgccg ttgctttgcg taaccgctat cgccgtttgc
    87901 agttagatga aaaaatgcaa caagatatta caccaaaaaa tatgctgatg atcggaccta
    87961 caggggtcgg taaaacagaa atcgcacgac gtttggcaaa aatcgtcaat gcaccatttg
    88021 tcaaagtcga agcaacaaaa tttactgaag tcggttatgt cggaagagat gtagaatcaa
    88081 tggttcggga tttagtagaa aatgcgatcc aaatcgtaga aaaagagcag tacagccgtg
    88141 tatacacaag tgctaaaaaa aatgcagaaa aacgtttggt aaaaatcttg gtacctggta
    88201 tcaaaaaaga acagaaacaa tccactaatc aatttgaaca aatgatgaat ctttttaatg
    88261 ctagtcagca aaataccgct gaaccgcaag aagaagtgac agaagatatt cgaatcaatc
    88321 gccgtacagt cttggaacaa ctacaaaagg gtttactgga tagtcgtgaa gtaaccattg
    88381 aagttgaaga ccaaaagaaa cctgcaccaa tgatgaacaa tggattggag caaatgggga
    88441 tcgacctaaa tgaaactcta ggtgctttga caccgaagaa aaaagtggaa cggacggtaa
    88501 cagtcaaaga agctttagag ttattgatca aggaagaatc agcaaaatta gtcaaggatg
    88561 ctgatatcca tagtgaggca atcaaattag cggaagaaag tggaattatt tttatcgatg
    88621 aaatcgataa gatcacttct aaatcacagc aatctggaga agtatccaga gaaggcgtcc
    88681 aaagagacat attgccaatt gtcgaaggtt cacaagtaaa cacaaaatac gggatcatcc
    88741 aaacagatca cgtcctattc attgcttcag gagctttcca tttgtctaaa ccaagtgatc
    88801 taattccaga acttcaagga cgcttcccga tacgggtaga attagatgat ttgacagctg
    88861 aagattttgt gaagattctg accgaaccaa ataatgcttt agtaaaacaa tacgtcgcgt
    88921 tgatcggtac agaaaatgtg tcagttacgt ttacaaaaga agcaattgaa cggatcgctc
    88981 aaatcgcttt cgatgtcaac cgtgacacag ataatatcgg cgcacgcaga ctgcatacca
    89041 ttttggaaaa actactagaa gatctattat ttgaagcacc agatatgcaa atgggagaaa
    89101 taacgatcac agaagcatat gtggatgaca aacttggctc aattgcggca aatgaagatt
    89161 taagtcgcta tattttataa aaaatcggag gacgacaatg acagacttgc taacgaaaac
    89221 ccgcaagata aacacacttt tgcagcaaaa gaatactttt gacatgcaag cagatttgcc
    89281 ttacgataaa atggctgtca cactaggtgg tattcttgac agcaacacct atatcatagg
    89341 aagtgacgga gtattactag gttataatga acgtcacgat gtgaacaatg aacgaatcaa
    89401 aacaatgttt gttgagaaac aatttcctga atcttatact gatacagtgg cacagttgat
    89461 gaaaactgaa gctaatatcc caattactag tgatattact gcatttccgg tagagtcaag
    89521 agagaaatat ccatttggtc tgacgactgt cgttccgatc tttggagctg gcgaacgttt
    89581 gggtacgatt atcttatctc gtatggaaca atcgtttgca gatgacgatc tagtcttagc
    89641 agaatatgga gctacggttg tcggtatgca gatcctttat cagaagtctc gaagcatcga
    89701 agcagatgta cggagtgcaa cggctgtcca aatggcaatc aacacattat cttatagcga
    89761 attgaaggct gtacaagcta tctttgaagc attggatgga gatgaaggtc gtctgactgc
    89821 ttctaatatt gccgatagta tcggcatcac tcgttctgtg atcgtcaatg ctttacgaaa
    89881 attggaatca gctggaatca ttgaatctcg ttcgttaggc atgaagggaa cttatttaaa
    89941 agtattgaat tcccgtttta aagacgagtt agcaaaacac agttattaga agtaagggga
    90001 ctggggcaga tagaaatgtt tgttccagcc ttcccatttt aaaaagtaag tcgaagttgg
    90061 aggaatggca atgactgtta ttattcaaaa tgaccagctg atcgccgaaa tcgctgaaca
    90121 cggtgcggaa ttgatcagtc tgaaatcaaa agaacatggt ttagagtata tctggcaagg
    90181 tgatccagcg tattggggca gacatgcacc ggttttattc ccttttgttg gacgtttaaa
    90241 agatgatcag tatgtttatc aagggaaaac atatcaaatg gggcaacacg gatttgctcg
    90301 ggatatggat tttgaagtca ttgaacatgg acaagaaatg gctagtttca tcttaaggag
    90361 tacgccggag acattagaaa agtatccatt tgattttgaa ttagtgatca gctatgaatt
    90421 aggaggagac ggcatcacgg ttcattatca agtggcaaat accggtgaaa aagaaatgtt
    90481 cttttctatc ggtggacatc ctgctttcaa tgtacctctt gaagaaggat tgtcatttga
    90541 agatttctat ctggcatttt ctccattgaa atcaagatta cgcctaccat tgaaaggccc
    90601 attcatcgat atggatcaaa agacgttagg tcagacaaat acgaatctgg ctttgaatcg
    90661 tgaacttttt gagcaagatg ccttggtttt tgaaacaagg ggtctaaatg cgtacgccat
    90721 tcgaagtgaa aaatcttccc atagcgtaac tttaagctat aaagatatgc cttatgtagg
    90781 gatctggtct ccttatccaa aagaagcgcc tttcgtttgt atcgaaccgt ggtgcggaat
    90841 cgctgacacg gtgaacagta gtggaaactt gatggaaaaa gtagggatca atcaactagg
    90901 tgcccatgaa atcttcaaga caaaatattc catcacagtg aagtaagagg ttgtgaccga
    90961 gaagttagca gggaacaccg tttaccaagg tgtgtaaaaa agctatcctg taagtaataa
    91021 gggagtgtga catcgatttg tcacactccc gttttatctc tttggaatga aaaagtatca
    91081 ggattttttc ttgctgctat tcaaaccaaa cgggattcga ctttcagtat ggtttctgat
    91141 acgcttgata ttgtctttat gccgataaaa gataaaggaa gaaactaaaa aggcaatgat
    91201 cgtcagtaac caattgggct tagccaaaat cacaggagct acataaggaa ggacgatcgt
    91261 agataaagtg atcaatactg cactgatcat actgctcaaa ctcaccatac ttgtacaaaa
    91321 taaactaacg ataaagatga tacaagaata aacaaaaaat acaggattaa atcctaaaag
    91381 cattcctgca cttgtcgcaa cagcttttcc tcctttgaac ccagcaaaaa tcggaaatgt
    91441 atggccaaga atggcgcata ccccaaacca aagagggtta atcccagaaa ggtggaagat
    91501 catcggcaaa caagtagcca atgtaccttt taaaatatcc ataagcagga caacaatccc
    91561 ggctgttttg cctaatacac gaaatgtatt ggtcgttcca gtattaccgc tcccgtgttg
    91621 tcggatatct tttttgaaaa acaatttgcc aatccagaca ccggaaggaa tagaacctaa
    91681 aagatatgct aaaataagta ataagatcaa tttcattttt taccctcttt caagttgaaa
    91741 actatccttt attttagcat gaataggtaa caggaacaat tgaaaaaatg aaagatacaa
    91801 gtataataga tggaataaaa agaaaagcaa ggggtggcag aaatgtctgt aaaaaatcca
    91861 acacaagaaa cgattttcaa ctatttggaa gaagcaaaaa atattgccgt cgtaggcttg
    91921 agcaataaac cagaacgaac aagttacatg gttgcacagg tattgcaaga caatggatat
    91981 aaaatcatac cagtaaatcc attattggct ggtgaagaaa ttctaggcga gaaagtctat
    92041 gcgaatttga cagaaatcga tgatccaatc gatatcgtag atgtatttag acggagtgaa
    92101 tttttacctg aaatagcagg tgattttttg aaaactgatg ctaaagtgtt ctgggcacaa
    92161 ttagggattg aaaacaaaga agcagctgag atgctaagaa aagcaggacg tacagatatc
    92221 gtaatggatc gttgtattaa gattgaactt ggtaagttga aagaaaacca aaaataaaaa
    92281 tgaccacaaa gaagagatga tcgatagagg ggaatgtcga aaaagcggtt aggagataat
    92341 taaaattgat ttctcgtcta ccctcttttt tttcacgacc ttttctagta tgataatcgt
    92401 ggtgcggttt tgccgcaaag tattattgaa ggagcgtttg ccttggcaaa aaaagtaaac
    92461 aacgaataca atgactcgtc catccaagta ttggaaggat tagaggcagt tagaaaaaga
    92521 ccagggatgt acattggatc cactgacagc cgaggcttgc atcatttagt ctatgaaatc
    92581 gtcgataatg cagttgacga agcattatca ggttatggca gtgagattga tgtgaccatc
    92641 catgaagaca atagtataac tgttgcagat agcggacgtg ggatgcctgt aggaatgcat
    92701 gcttccggaa taccaacagt tgaagtgatt tttactgtgc tgcatgctgg cggaaagttt
    92761 ggtcaaggag ggtacaaaac ttctggtgga ctgcacggtg taggagccag tgtggtaaat
    92821 gccttatcga aatggctaat tgtaacgatc gttagagatg gcgtagagta tcagcagaaa
    92881 tttaaaaacg gcggtaaacc tgacggtact ttgaaaaaga taggaaaaac aaaaaaagca
    92941 aacgggacga ctgtccattt tttaccagat gatacaatat tcagtacaac gaaattttca
    93001 tatgaaattt tagccgaacg gttaagagaa tctgcctttc ttctaaaagg cgttaaaatc
    93061 tctctttctg atcttcgtgg agaagaacca gtcaaggaaa tttttcatta cgaagaagga
    93121 atcaaagaat ttgttgatta tctgaatgaa gaaaaagata cattgacacc agttgtttat
    93181 ttttcaggag aaaaagaagg tatcgaagta gaggtcgctt atcaatacaa tgacggttat
    93241 tcagaaaatg ttttatcttt tgtcaataac gttcggacaa aagatggggg aacccatgaa
    93301 gctggtatga aagcggcgat gacgaaatct tataatgaat atgcgagaaa agttggtttg
    93361 ctgaaagaac gggacaagaa tctggaaggt agtgatttca gagaagggtt agctgctgta
    93421 ctttctatcc gtgtacctga aaatcttctg caatttgaag ggcaaacaaa agaaaaactt
    93481 ggtacgccag ttgctcgtac cgtagtagat aacgtcatca gtgaacaaat gggcttttat
    93541 ttgcaggaaa atagcgaaat gagccagatg ttggtccgta aagcaatcaa agccagagaa
    93601 gcgagagaag cagcacgtaa agccagagaa gaaagccgaa atgggaagaa gcgtaaaaaa
    93661 ggcgaatctc ttctttcagg aaaattgaca cccgcacaat cccgaaaccc taagaaaaat
    93721 gaattgtatt tagtcgaagg ggattctgct ggcggatctg ctaaacaagg aagagacaga
    93781 aagttccaag caattctacc tttacgagga aaagtcatca ataccgaaaa agctaaaatg
    93841 caagatatct tgaaaaatga agaaatcaat acgatgatct atacgattgg tgcaggagtc
    93901 ggtcctgagt tttctatcga agactgtaat tacgacaaag taatcatcat gaccgatgcg
    93961 gatacagacg gcgcccatat tcaagtatta ctgcttactt tcttttatcg ttatatgaaa
    94021 ccgctgattg aagctgggaa agtatatatc gcgttaccgc ctttatataa agtatccaaa
    94081 ggacaaggaa agaagcaagt cattgaatat gcgtggacag atgacgaatt ggcagcaatg
    94141 attaaaaaag tcggcaaagg atatatgctg cagcgatata aaggacttgg agagatgaat
    94201 gcggaacaat tgtgggaaac aacgatggat ccgacttccc gtacgttgat ccgcgtccgt
    94261 atcgatgatg ctgcgcaagc tgaacgtcga gtaaccacac tgatgggtga caaagtagaa
    94321 cctcgaagaa aatggatcga aaatcacgtg caatttacgc tcgaagaaga tggcagtatc
    94381 ttagataaaa aagaggatac tgaaatctct ccttcagttt ctaatgattt attagatgaa
    94441 gaacgagcag ataaaaatga aaacaatcag ttatttgaag tagaatagga ggtcacctga
    94501 tggaaaatcg acaagaagta caagaattaa ctttagaaga agtgatgggt gaccgcttcg
    94561 gacgttattc caaatatatt atccaagaac gtgcactgcc tgatatccgt gatggattga
    94621 agccagtgca acgccggata ttatttgcca tgaacaaaga tggcaatacg tatgacaaag
    94681 gattccgtaa atcagcaaaa tctgtcggaa atatcatggg gaattatcat cctcatggtg
    94741 acatcagtat ttatgaagcg atggtccgca tgagccaaga ctggaagttg cgggaagtac
    94801 tgatcgaaat gcacgggaat aacgggagta tggacggtga tccacctgct gcgatgcgtt
    94861 atactgaagc cagattatcc aagttaagtg gagagatgct agcagatatc gagaaagaaa
    94921 cagtcgatct cgtgtggaat tttgatgata cagaaaaaga accaacagtc cttccagctc
    94981 gatacccaaa ccttctcgtc aatggatcga caggtatatc tgctggatat gcaacagaaa
    95041 tcccgactca taacttagct gaagtgatcg atggcacaat ctatatgatc gatcatccac
    95101 aagcgagcct tgaaaaattg atggaatata ttcctggacc tgactttcca acaggaggga
    95161 tcttgcaagg aaaagatgaa atcaaaaaag cttatgaaac aggacgagga aaagttattc
    95221 ttcgttcgaa aacaaagata gaggcaatga agggtaataa acagcaaatc gtgatcacag
    95281 aaatcccata tgaagtaaat aaagcgacct tggtgaaaaa aatggatgag atccgtttga
    95341 ataagaaaat cgatggaata gctgaagtac gagatgaaag tgatagaaca ggtctgcaaa
    95401 ttgtcgtcga attgaaaaaa gacgccaatg ctcaaggaat tttgaattat ttgttcaaaa
    95461 acactgagct acagatcaat tacaatttca atatggtcgc tatcgaccat atgactccgc
    95521 atcaagttgg actgaaagac attttaagaa gttatatcga gcatcgaaag caagtcataa
    95581 caaaacgtag tcaattcgat ttagccaaag ctcaaaaaag acagcatatc gtagaaggat
    95641 tgatgaaagc tttatcgatt ctggatgaag taatcgcaac gattcgtgaa agtaaagaca
    95701 aaaaagacgc caaaaagaat ttagtcgacg tctttcaatt tacagaagaa caagcagaag
    95761 caattgtcac attgcaatta taccgtttga cgaacacgga tatcacagag cttcaaaagg
    95821 aatccgaaag cttgattgcg caaatcacag agttgaataa aatcctttca aatgacaaag
    95881 agcttttctc tgttatgaaa aaagaattgc gagaagtgaa aaaaaattat tcttccgctc
    95941 gtctaacgac aatcgaagac gaaatcgaag aaatcaaaat tgatacgcaa gtcttagtgg
    96001 cacaagaaga cgtaattgtc agtgtgacgc gagaaggcta tgtgaagcga acaagccttc
    96061 gttcttatag tgcttccaaa ccagaagaaa tcgggatgcg agaaggcgac tacttgctat
    96121 actcaggtga attgagtaca ttggaccatg ttcttctgat cacaaataaa gcaaatgtga
    96181 tctaccgccc tgtccatgaa ctacccgatt tgaaatggaa agatgctggt gagcacattt
    96241 ctcaaacaat ctccaatctg tctgtagacg aatcgatttt agctgttttc ccatatcaaa
    96301 aaattcaagc agagaaaaca tttgtattca tcagcaagaa tggattgatc aagcaaacac
    96361 gaatgacaga gttcgaacca tggcgcacct ataagagccg tccgctcagc tgtatgaagc
    96421 taaaggcgga agaagatgaa ctgattgctg tgtatctgaa agaagatcag ccaggcttag
    96481 atgttttctt agtaacgcat caaggaatgg gtttgcgcta tcctttaaca gatgttcccg
    96541 ttgttggagc aaaggcagct ggagtgaagt ctatgaattt gaaagatgga gataggatta
    96601 tcaacgggct gcttgtgtta gcagaaggtg atacgccgat cgtaatcgtt actcagcgag
    96661 gagctgttaa acgcatgctt gctcaagaaa tcagccaaac ttcacgtgcg aagcggggag
    96721 tgacggtcat gcgtgagctg aaaaaaaatc cgcaccgtat tatctatatg tcggaaggaa
    96781 gatcaaaaga aataaccttg atgaatcaaa aagggcagca gttaacgatt gacccaactg
    96841 atttccctat aggtgatcga acatcgaatg gatcatttgc gatggatgag aaaaaaggtg
    96901 gagaagtcat cgaagttatc gatgctcctg agattttcat cgagtcgtaa ctgttgtagt
    96961 attttaatga agagacgcca tctgtattaa tacaggtggc gtctcttttt cattcatttt
    97021 taataaatcc ttatacgttt gcaaaaaaag atgaaagtgt tcacaatgct taaatgttgg
    97081 tatgtcaacg ttgatttaaa tatatgtaaa taaaacataa aaattgttaa ataaaaaaca
    97141 agaaaaccct tgcaaagata gggtgctgtg ttatactaat cacgtaaaaa ctgttacata
    97201 aaacagaaat ttaggaggtc catacaatgg agcaatggaa tggatttaaa ggtaccaaat
    97261 ggaaagaagg cgtagacact agagacttta ttcaaaataa ctacactgaa tatcgcggtg
    97321 atgacagctt tttggaaggc ccaacagaag caacagaaaa attatgggat gaattgcaaa
    97381 agttaaatga tatccaattc gagcgtaacg gtgtctatga tatggacaca gaaatcgtat
    97441 caactattac ttcacacgat gcaggctatt tggataaaga tttggaaaaa atcgtcggtc
    97501 tacagacaga caaacctttg aaacaagcat tcatgccgtt cggcggaatc aatatggcta
    97561 acaatgcgct aaaaagcaat ggctatacac caaacgatga attgacacat attttcactg
    97621 actggcgcaa aacacataat caaggtgtat ttgacgctta tactgctgaa atgcgtgctg
    97681 ctcgtaaaaa caaaatcatt acagggcttc cagacgctta cggtcgcgga cgtatcatcg
    97741 gtgactatcg tcgtgtggca ttgtatggaa tcgactattt gatggaacaa aagaaaaaag
    97801 atcatgatat gactggttat catacaatga gtgaagaagt gattcgttta cgtgaagaaa
    97861 tcactgaaca atatcgtgca ttagcgcaaa tgaaagaaat ggctgcgaaa tatggctatg
    97921 atatttctaa accagctgca aatgcaaaag aagctgtcca atggctatac ttcggatatt
    97981 tagcagcaat caaatcacaa aatggtgctg cgatgtcaat cggacgtatc tcagcattcc
    98041 ttgatatcta tatccaacgt gatttggata atggagtaat cacagaaaaa gaagcacaag
    98101 aattgatcga ccacttagta atgaaattac gtatggtcaa attcgcgcgt acacctgaat
    98161 ataaccaatt attctcagga ttccctatct gggctacttt atccattgca ggtatgggat
    98221 tagatggtcg ttcattagtt acaaagaatg atttccgtct gcttcataca ttaacaaata
    98281 tgggaccttc accagaacca aacttgactg ttttgtattc tgaacacctt ccagaaggat
    98341 tcagaacata tgctagcaga atcgctatcg aaagttcttc gattcaattc gaaaatgata
    98401 atcagcttcg tgaacaatgg ggttctgatg attgtgcgat tgcttgctgt gtatcaggaa
    98461 cagttgtcgg aaaagacatg caattctttg gcgctcgtgc taacttggct aaaacactat
    98521 tatatgccat caatggcgga gtcgatgaag tgactggcgc ccaagttgga ccagaatatc
    98581 gtccaatcac atcagaaata ctagactttg aagaagtgaa acataacttc atgaatatga
    98641 tggattggtt agcagaacta tatgtcaata cgttgaacat cattcattat atgcatgata
    98701 aatattctta tgaagcagct cagctggctt tgatggattc tgacttgcaa cgcacatttg
    98761 ctacaggtat tgctgggatc tctcatgcgg cagacagctt gtcagcgatc aaatatgcaa
    98821 aagtaaaagc aatccgtaat gaaaaaggaa tagcagttga ttttgaagtg gatggcgact
    98881 tccctaaata cggaaatgat gatgaccgtg cagatgaatt agtttcatgg atcttggaat
    98941 acttcatggg acaaatcaaa cgtcataaaa cttaccgcaa ctcaaaacca acaacttcat
    99001 tattgacgat tacttcaaat gttgtttacg gtaaaaatac aggaaatact cctgatggcc
    99061 gtgaagctgg aaaaccactt gcgccaggag caaatccaag ttacaatgcg gaacaaagtg
    99121 ggttattagc tagcctgaac tcaacagcta aaatgaatta cggctgtgca ttggatggaa
    99181 tttcaaatac ccaaacaatc aatccttcag gtcttggaaa agaacaagat acaagaatcg
    99241 aaaacttgcg taatgtctta gatggatact tctcaaaagg agcttatcat ttgaatgtca
    99301 atgtattcag taatgattta ttgcgtgatg caatggaaaa tccaatgaaa tatccgaact
    99361 tgacgatccg ggtatctggt tatgcagtta aattccgtga cttgacaaga gaacaacaat
    99421 tagatgtctt gatgagaact tcacacgaca gaatgtaaaa agttcgtgaa aaaagttttt
    99481 cgacttagcg tcgaaaggac gttgaatagc catcgcatca aaatcgaata atcagtatgc
    99541 ttatttgaaa gaaacgattt acaggggcag gacttgtatg ttccgtccct gtaaatttta
    99601 cacataacga agcggcaatt gcgaaaaatt ttgttcagaa agcttcgctt cgacagctaa
    99661 cttgtactta aaatgaaatc aaagaaaaga tgtgaactta aatggaagaa aaaacaatcg
    99721 gctatgttca ttctatcgaa actttcggtt cagtagacgg acctggactg cgctttgtcg
    99781 tgtttatgca aggatgccgc atgcgttgcc aattttgtca caatccagat acttggaata
    99841 ttggcggagg gaaagaatac acagcagatg aacttttaga taaagcagaa cgcttcagac
    99901 cttactgggg agataaaggt ggtattactg ttagtggtgg agaacctcta ttgcagatcg
    99961 attttttgat cgaactattt aaaaaagcaa aagagcggaa gatgcatact acattggata
   100021 catgcggaaa accttttacg tatgaagaac ctttcttttc acgttttcaa gaattgatga
   100081 agtatacaga tttactgtta tttgacatca aacacatcga taatgaagag cataaaaaac
   100141 taacgcattg ggacaatgaa aatattttag aaatggctca atatttgtca aaaatcaaca
   100201 aaccggtttg gattcgccat gtactagttc ctgagcgaag tgattatgat gaatatttga
   100261 tccgactaga caactttatt caaaccttgt caaatgtaga cagagtagag attcttcctt
   100321 atcatacgat gggaaaatac aagtgggaaa cacttggttt gaaatatcca ttagaaggga
   100381 tcgaaccacc tacaaaagaa cgtgtcgaaa atgctaaacg attgcttcat acagaagagt
   100441 atacaaaata tttaacgcga taggtcgcat cggaaagaag ataagtattg cttctttccg
   100501 tttttttgct attattaaat aggagaaatc acaaaggagc gaatgacatg tcaaaaattt
   100561 tagtttttgg tcaccaaaat ccagatacag atgcaatcgg ggcagccatt gcgttttcac
   100621 acttgcaaaa tgaattaggt aaagaaacag aagcagttgc tctaggtaca cctaatgaag
   100681 aaacacaata cgcattagac cactttcagc tatctgcacc acgagtagta gagtcagcta
   100741 aagcagaaaa tgcagatgtc atgcttgtgg atcataatga attccaacaa agtatttcag
   100801 atatcagcga agtaaatatt ttagctgtag tagaccacca tcgtattgca aactttgaaa
   100861 cagctaatcc attgtactat cgtgcagaac cagttggatg tacaagtacg attattttaa
   100921 aactatataa agaaaaccaa gtaacaattc ctaaagaaat cgcaggaatc atgctctcag
   100981 ctatcatttc agatacattg ttgttcaaat caccaacatg tacgcctgaa gatgaagcag
   101041 ctgcaaaaga acttgcagca atcgctgaag tcgatctaaa cacttatgga cttgaaatgt
   101101 tgaaagcagg aacaaatcta agtgataaat cagctgcggt tcttcttgat ttggatgcaa
   101161 aaagtttccc aatgggcagt tccaacgttc gtatcgctca agtcaataca gtggacctta
   101221 atgaagtgat ggatcgacaa gcagagctag aagcagcaat ggaagatgaa atgaaagcaa
   101281 atggctacga tctgttcgta ttagttgtca caaacatctt agacagtgat tcagaattac
   101341 ttgttgctgg taaaggaaaa gaaaaagtag aagaagcttt ccaaacaact ttgaccaaca
   101401 accgtgcttt gcttaaaggt gtcgtttcac gtaaaaaaca agtcgtacct caattgacgg
   101461 ctgtatttag ctaatcaaat ggtagtatga agcattcaaa atgaatggat aagcgattga
   101521 tataaaaaga aacatagaac atactaaagg ccgaagaaat ggaggagaat aacagtcaat
   101581 tatgactctt gttcttcctc ctttttacgt aaaagccttt taagtaaaat aaaacggata
   101641 gaaaagagaa catatatgaa ctattattca aaaaataagg aaaactttta tcaaaaactg
   101701 accgatgatc cgcttttttc ttcattgacc gattatctat atgaacatcg agaacaagaa
   101761 acgattctaa gagaattgaa aaaagaattt tcgcaaaata aattttccca ttttcttgat
   101821 ttattgatcg atgcaggatt aatcaagagg gaagaacgaa gatatcattt gaactttcca
   101881 atatttgatc ctaaagatta cttgcaacaa gccacttcgg ctgctgaaac catagctgaa
   101941 caattgaaga gactctctgt tgatgaacaa aaattagcga tgggagaagt tatttgggcg
   102001 tattgtttcg aagatgaacg gaaagaagcg tatttttatg gagtaagaaa cagccgagag
   102061 acagaattgc tgaggacaac tgcaggaaat gagaagtacc gttttatcac actttcctct
   102121 atagaacact tcccgcttac tttggctaat tacttttttg tacagaagaa tcagcttcct
   102181 gtaacgaagg cattcaaaga attagccgaa cttattggag acgtaaatga atcgtacttt
   102241 tttgatcaaa tagaagttat cgttgacagg atacgtaaga ataaatataa aaatcgccgg
   102301 cctagtattt tccatcagtc tctacttgtg acgaatacta taaaggaaga agaatcattc
   102361 acattagaat tacctattgt cgaaaaaaac aattttgaga ttgaattacc aacattggat
   102421 ccttcattga caatggagga aatggccttt cttaaacgac aaatcttttc tgagctgagc
   102481 aagaaattta taccgcatgc attttcttat atcaaagaat atggaacagt tttagtgagt
   102541 aaaacctaag agagcagtaa gcaaaaatta tactgactct tgcaggagga gcctttctct
   102601 tcctttatgg ttaaaagaat tatttgagta ttttgcctat ctaccaccta ttagattcac
   102661 tacatggtct ggaaacaaag gaatgcaaaa aaatggtgag aaatgtggaa tgacaaagga
   102721 agtagtgata agaaaagtta gatttttaaa taatcaatat tatgattcag tcaagtatgg
   102781 cattttatgg gaagaactag ctgattagat taggaagtcc atttgataat ccagaatcac
   102841 taagaaacga atggcgagtc attaataatt tatccaatct tgggttattc ttttagattg
   102901 aagtgtttaa aactaaaaaa gcatttatga agtcgtaata gtcaggcttc aaaatgcttt
   102961 ttattttgtt tgttttttct ttgccacata aatacaccta gactgacgat gaagagcata
   103021 tccaacagat ttcctgcgac ttggatcgtc gaagggttgg tcagtggcat taaagcaagg
   103081 acaaaaaagg aaaacaagct gtaaataaaa caggtgacag gaactaatcg aaagaagagc
   103141 ggacatttca attggctaaa aatgagtgaa aaaataaaat aagtaaaaat ggataaaatc
   103201 acgactaaac cattcatgat aaagaagaaa agcgtattgt gattaaacga ataaaaaaga
   103261 attgctaaaa aagaaaacgt tttaaatgca atcaatacgc ttgaagcttc gtttaacgta
   103321 ccaggatgtc gatgaaaaaa ataggcaccg aaataaacag aaaacagtaa gccgcaaaga
   103381 gaagacaaaa tcaaaaaaaa cggattttct tcggcttctg tgatatcaga atgatccaaa
   103441 agcaaccagc ctaatgcact agaaggcgca tgtgaggtct taaggtatga ataacataga
   103501 aaaaataaga tcgtcaaagt tgcaaaaaaa gagcctaaat gtaaaaaatt agtggttcta
   103561 cgttgaattt ccataatatc tccaaattaa attgataagt atataaagta taataacaaa
   103621 ttgatgagta tatgtcgatg ttttttaatc aaaataataa ataaaaactg tctaacattt
   103681 aaaatttaat ttagatatta gacagttttt aagtttgtga gttattttcc ttgtcgtttt
   103741 ctcacttttt tagtccagaa accacctgaa atatattttg gctcataaga aatgataaaa
   103801 gcacgctctt cgatttcttt gatcaggcga tacagttcac gttcgctttt tctaggagaa
   103861 agtatttcga gaactagccg ctcaccttcc agccccattg cagaagtctg tgtcacacca
   103921 taaccgtgtt ctctcagtat acccggcaaa cttttatctt ctgcgctatt tgctggcaaa
   103981 atcgttgtga ccatgatgta tcctaatgcc aatttgtctt caatcaaaat tccgacactg
   104041 atacctactg cgtaacctaa cgcatagaca aataaattca gtggattatc taaacgatct
   104101 aaaacaaggg ataagccgac gatataaatc gtgatctcga ccatactgac aagtggagca
   104161 atcagtcgat agcctttcat tgtcaacatg aaacgtaacg tgttcagagt gatataagca
   104221 aaattaatga ggaagatcat ccccaacatt tttggatcaa tcatttgtaa aactcctttc
   104281 atttatataa caacaatatc aaaaaaaatc gtaagtgaag aaaaattgaa actttataca
   104341 tacaaaaaaa tgataaaatg attataatag aattataaag ataggttagg tgattaaaat
   104401 gaaaacggtc aatcgtgtgt tttgtgccag ccacgtgcta agtctccttc tcagtatata
   104461 cttaggtgtc tattcgattc aacagccaat tgaggtagag aacattgttt ttcagatgtc
   104521 gctgacagat ggtttaattt taagcgtttt tttctttttg atactgttta ttggtaatat
   104581 tttcggtagc gttgccagtt ttttgaattt ttctatttat ccactccttt cgctagcatt
   104641 aggagtggtg ggactttgtt ctctgtgctt atttcccgag ccattcagtc ctgcatttat
   104701 attatttggt acactgaacc tgttccagac aactgttgga gcatggttgc tatggcgatc
   104761 aggaaattta atgaaaatag gtgagtaaca attgaatcca attatattga aacgttctgt
   104821 ccatcatatt ccagtgttag aagttgttct gaaagaatta agagaggaac gtattcccgt
   104881 tgtcatctat tatcacggat ggcagacaag taaggagtta gttttgacgc aaggaagaaa
   104941 aattgcgcag cagggcattc gtgtgatcct gccagatgcg atgaatcatg gggagcgcaa
   105001 acagccggtt tcttctattc catcctatac attttgggat agtatctacg gaaatctgtt
   105061 tgaatttgac acacttatca agcatttaga aaaaagaggt cttctacatg atcagcttgc
   105121 agttggcggg gtttcgatgg ggggaatgac aacatgcgcc ttgttggcta aacatcctca
   105181 tatagtagcg ggcgtgtgtt tgatgggttc ccctgcacct ttggaatatg gaaaagaaat
   105241 cgtaaggcgc gcatcggaat ataattatgt cgtaccaaaa gactattttg atttgatttc
   105301 atgggttaag agctatgatt tgtcattgca gccggaaaag ttagctggac gtcctctgtt
   105361 cttttggcat ggacaagctg acgaaaaaat cccttatata caaacggaac gatttgtaga
   105421 aaaaaatcgg cataagtctt acggaaaaga aattgttttt cgttcctcaa aaacacagcg
   105481 acatatggta caaataccac taatggaaga agcttccact tttttagcaa aaaatttgat
   105541 aaaaaagtat aaataattga aacggaaaat cactcatgac gatagaggat tttccgtttt
   105601 ttattttggg ctataataaa ctctgttagg aaaatttggt ataattgata gtaagaatga
   105661 caacatgtta gaaaggaaga gagcatgccc actttagcag atgttgcaaa acgtgccaat
   105721 gtttcaaaaa tgacggtctc tcgagtcatc aatcatccgg aacaggtgac tgacgaattg
   105781 aaagagttag ttttctcagc aatggctgaa ctggattacc gtccaaatat tgctgcaaaa
   105841 gcacttgtca cgaatcggtc gcagatcatc aaattattta tactggaaga aatcgacaca
   105901 actgagccct attacatgaa tttgctgatg ggaatcgcta aacggatcgg taaagcgcat
   105961 tattctctcc aattagttac aaatgatgcc ttcgacgtcg gttcttgtga tggatacatc
   106021 atcacaggtg tcagaaaaaa agacttcgat tggatcgacc gtttggaaaa accagttgtc
   106081 ttgtttgggg aaaattctga aggatatgat tatgtagaca gcgataatga atatggtaca
   106141 gcaaaagcaa cgcaatatgc cttagaaaga gattatcaaa cgattattta tatcggtatc
   106201 gaagtggacg agccttttga aatttcaagg gaaactggtt atttatctgt gatgaaggaa
   106261 gttgatcttc ctagtaaaat cttgcggttt ccaaatcatt cgacagaagt agaaagatat
   106321 atgacagaaa actgggcaga ttttacagat aaaacttgtt ttgtatgtag ttcagatcgg
   106381 ctagcactag gagcagtaag agggattata aatgctggag gacacttgcc cgaagaattt
   106441 ggtgtgattg gatttgatgg ggtattttta gaccaaatca gttcacctaa attgacaacg
   106501 atcaagcaag atattatacg tatgggtgaa gtatgtggag aaatgttgtt aaaaaaaata
   106561 gaagaaaaag gggcgagtca aggttatcgt cgtttttttc ctgaactagt tatcagagag
   106621 acaacgaatt aagtcttatt actatatata tatttatgaa attcatcgct attttcttaa
   106681 aataatcagc gcattgctac tgaaaacaat gaatctgtgc tattattgag aaaagttcca
   106741 tttttgagaa ggatggtttg aatgaaagaa atcagacgaa aacatttccg ttttcctgcg
   106801 tacgatgatg agttaggcgt aaaattaacc aacgacaaga agcgagtatt atttgacgga
   106861 caagaagatc ttttgactga acagaatcag tccccgtttg aacagatgaa agaatttcat
   106921 ttcacgaaca cgaacaccga gaaaatccgt cgcaagcgtc gtgcaacaaa tggattgaag
   106981 tcagctccgc gtaaggaaaa tttggaaaag cataaaggaa aattaccgga ttataccggc
   107041 cattaccaat cagaaatcac atcgacagga cgaaaaaaac tttttggtga ttcctctcgt
   107101 tctgtcagac aaagtgaaac aaggacagag tccaagcata ctacacgaaa cgcatctgtt
   107161 gacacgaagg tgcgggagcg ttcttatttt gttcctaaat atgtacccgc atcgattatc
   107221 ccagacccta gagaaagcaa aatttctgag gatcatttaa tcgaatcgat gaaaaaaacg
   107281 gatgactctt atctgttgtt cgatacagaa ccgacgccgt atcaagaaaa aagaaatggt
   107341 gagccgtctg tacgaacatt caatcgaaca aaaacgttag aggaaacaaa gcagtcagaa
   107401 gaaaaaaaat cgaaaaaaag ccatggtatc ttagaacgct cattacaagg attgatcgat
   107461 gatcaaggaa actctttggg agaaaatagc tattttaaat aagtgatata caaatttata
   107521 ttcggctaca gttggaaagg aaacgctgcg gcgtttcctt attttatact ctatccgaaa
   107581 gtttatatcg tatcctcaaa tttttttgag tttaagcgaa ttttttctcc caataagtaa
   107641 gaaaataatg gcaaaataaa aaaacaaact attttcgcag atcgtttgca aaaatagttt
   107701 atttttttat aaagaagatt ttactgaata atatcatttt agtttacata atgatatttc
   107761 tgtaaattaa ataaagtagt gaaaaataag aatcagtgct ctaactgttc aagaggatca
   107821 agtggttcaa atgtttctgt agtctgtttt gcttccaatt ggggcaaaac agatccaatt
   107881 tccagatact tcactttatt caatgtataa gatagaatag aacagctaag taatgtatac
   107941 agaaaatgtg tgagatccaa ataaagcaag gagacaacta aaataccaaa agtaatcaag
   108001 aaaagacttt tgccaatctt aatatgaaaa tatttttcaa tggcttgata aatgatatct
   108061 gttccgcctg tgcttccgcc gaatcgaaag acgagaccgc aaccaatgcc agaaagaata
   108121 cctgtcatca aactattgat cagtagacta tctacagcaa aatgtatatg aaggctctcc
   108181 cataaatgta aaaagaaaac tagcgcaaat gttccgacga tcgtccggag aaaagcgtgt
   108241 tttccaaaaa gaaacaatga gataagcaat aaaggtaaat taaaaagcag tgaagtgaca
   108301 gaaggagcga atccaaaaag attatgcaaa agcaaagcaa taccagtaac cccaccatct
   108361 gccagcttag atggaatatt gattcctgtc acagctaatc cgtagattcc tgcgcctaaa
   108421 atgattccgc acaattctgt aaataaattt aattttttca tttctagcct cttttctttt
   108481 gaaaattttc agcaacttct ttattatact gacttatact cttacttcaa gaggaaaatg
   108541 aaaaaaaatt atttttggct gtttcttttt atttatcaaa taaggagtgg aaaaatgcga
   108601 gcagcagact tattgacaat tcttacaaaa tcacccaaaa aaacagagta tcaaggagtt
   108661 tttttggctc aagaacaaaa actggtgcct gtgacaatgg tccagataaa taaagcaaat
   108721 caatttatct ttttatttga acacggcaaa gcaccacttg ctatgaaaga catctttctt
   108781 tttttgatga agaaccgtga gaaagctgtt tattatcagt caaaagaaga actcattcct
   108841 ctttatggag tgaaagagat agaaaataaa gtggtgatat aagtaaaaat aagaaaacaa
   108901 gacgtttatg atgtcaaaac aaccattttt tacatttttg gcaaaaaagt gtcatgatac
   108961 agtataatat tcgttgaaca ggccaataaa ggtgttctcc cccacgagat ttctacttta
   109021 ttggctgttt ctttttatta aaataaaagt tgtgtgtgta aaaaagatat agctgattcc
   109081 aagtgacaat ttcgtataga tttttatggt attcgtagtg aaaaaacgag aaccaaaaag
   109141 ttgatccgac tttgttgctt ggattctttt tttgtcagca tatttagagg tatttttttc
   109201 ttttttttgt tcgtgctgta aggttaaggc aagacaagtt agttgggaaa aaggaaagaa
   109261 atgtttatac ttaaagaata acagaaagga aggtcgcatg aataatttta tacaaacatt
   109321 aagtgaaaga aaaggcgagt tgctggaagc tgcatttcaa catctgtcca tttctctcat
   109381 ttctttgctg attgcagcac tgattgctat tcctttagcg atttgggcag ccaatcataa
   109441 aaaaatggca gaagtcttat tgcagatcac gggtgtgctc caaacgattc cttcacttgc
   109501 cttattaggt ttacttatcc catttgtagg gatcggaact gttccagcat tgattgcact
   109561 tgttatttac gctttgcttc cgattttcca aaacacgtat attggtctag ctgaaattga
   109621 cccgtctatt gaagaagcag cggtagcatt tggtatgtcc agaatgagac gcttgctgaa
   109681 agtagagctt cccatcgcat tacctgtcat tatctcaggt atccgaactg ccttagtttt
   109741 aatcatcggt acggctactt tggcagcatt gatcggagca ggtggattag ggacatttat
   109801 tttgttaggt attgaccgaa atacacctgt tttgacattg attggtgcga tcagttctgc
   109861 cttgcttgca attatattca gcggactgat tcgctggttg cagcataaga aacctcgata
   109921 ttccatcatt actttagcag cagtggtgtg tttatttggc ggcgtttctt tatatcagtc
   109981 tgccttgttt aaaaatgaaa ccatcacgat tgctggaaaa ttaggagcgg aacctgaaat
   110041 cctgatccaa atgtataaag aattgattga agacaacaca aaaacagaag ttgaattaaa
   110101 accgaatttt ggcaagacga gttttttgtt caatgcactg gatcaaggtc aaatcgatat
   110161 ctatcctgag ttcacaggta ctgtcctaga aagcttggtg aaggtacctg aagcaatgaa
   110221 aagtgctgat ttgacaaaag aaaaaacata tgacgaagca gaagaattat tgaataagca
   110281 attcgatatg acattattaa aaccaatggc ttaccaaaat acgtatgcct tggcagtcaa
   110341 gagatctttt gcgaacgaac atcaacttaa aaagatttcc gatttggcag ctatctctga
   110401 tcagatcaaa gcgggattca cactggaatt tattgatcgt tcagatggat ataaaggaat
   110461 ccaagaagca tatggcttga atttttcaag tgtacaaagc atggagccaa gtttgcgtta
   110521 ccaagcaatc aataatggag atgtcaatat tgtggatgcc tattccacag atagccagct
   110581 caaggagtac gatctagtga ctctagaaga tgatcgaggg ttattcccag cttatcaagg
   110641 cgcaccgctg atgaaaaaag attttgctaa agaacatcct gaaatcgtta aagcactgaa
   110701 taaattaagc ggaaaaataa cagaggatca aatgattgat atgaattacc aagtcaatgt
   110761 cgaaaagaaa aagccgacag aagtagcacg aatcttcctg aaaaatgaag gattagtaaa
   110821 ggaggaagat cagtgactaa attaatcgag ttcaaacatg tgcaaaaaaa gtatgatgga
   110881 aagtatgtca tcgatgacct aaatctggca atcaaaaaag gagaaatctt tgttttggtt
   110941 ggtccttccg gtagtggaaa aacaactact ttgaaaatga tcaatggatt atctaaacca
   111001 tcagcaggag acatctactt caaaggaaaa tcgttaaatg aatataatct gcagaaaatg
   111061 cggtggaata tgggatatgt gctgcagcaa atcgctttgt tcccgaccat gacagtcaag
   111121 caaaatattg aagtcatccc tgaaatgtta ggttgggaaa agcagaaaag agcagaccgt
   111181 gtagatgaac ttcttcaaaa agttggctta tctcctgata tttatcgaga tcgtatgcct
   111241 agagagttgt ctggaggaga acagcaacgg atcgggatca tccgagctat tgctgcaagc
   111301 ccagatgtga ttttgatgga cgagccattt agcgcattag atccgatttc aagaaactca
   111361 ttacaagaat tggttttgtc cttacacgaa gaattgggca cgaccatcgt tttcgttacg
   111421 cacaatatgg aagaagcaat caagctaggt gatcgtattg catttatgaa ggatggagaa
   111481 attatccaat gtgacacacc agagcagtta ttgatgaatc ctaaaaacga ctacgttcgg
   111541 catttctttg atgaaccgaa acagacgaaa gagtggcgag tagaagattt agtcgtcaat
   111601 ggatatttct taaatgaaat accagaaaat gctcgtcaac aagtttgctt tgatacgcct
   111661 atgaaagaag tatattcgct tctttcggtg tatccaagca ttgtgatagt agaaaagcaa
   111721 agaagtattg ggtcgctgac aagtaaagaa atctttgctt ttttaagtcg agaggaggaa
   111781 ggaaatgaaa acatatgatg caatcatcat cggttcaggt gtgagcggct taagtgctgc
   111841 ttatggattg aaagaagcag gtaaaacagt actagtggtc gaagaagatc tatggggcgg
   111901 gacttgtcct aaccgtggat gtgatcctaa aaaagtcttg ttaagtgcag tagaggcacg
   111961 taatcgggta aaacaattga gtggaaaagg ttttaacgag atcccaactg ccaactggga
   112021 agaacttcaa aaattcaaac gaacatttac ggatccagtc ccagaaagcc gaaaaaaaca
   112081 attagcagaa gctgaaatcg atcatctttc aggaaccgct cgttttttgg atgattcatc
   112141 tattgaagtc aacgaagaag tcttccatgc ggattactta gttttggcaa ccgggcaaag
   112201 acctacgatc ttaccagtgg agggaaagga atacttgaaa actagtgcag actttttatc
   112261 attgcctgta ctgcctaaag aaatcatttt tatcggtggt ggttatattg cttttgagct
   112321 agctacgatt gccaatgctg cagggagcaa agtaaccatt gtccatcata atcaacggcc
   112381 attaaaagaa tttgaggcgt ctttggtaga ggaagccgtc catcaaatgg aagcatctgg
   112441 cattcagttt gcttttggtg ttgaaaccca aaagatcatt tcagaaggta ctcgctatcg
   112501 tttagtcgga aaagagacgg aattagtagc agatatgatt ttttgtgcga ctgggagaca
   112561 gccgaataca gaatctttag cacttgagca agcgaatatc gtctttgata aacacggaat
   112621 tgcagtcaat gattatctgc aaacgagcaa tccaaaaatt tttgcgtgtg gagatattgt
   112681 ttcaaggaaa accccaaaat tgacaccagt cgccactttt gaaggaaatt atgtagctaa
   112741 gcggataacg gatgcaacaa gcgaacctat caaatatccg attataccta cgatcgtcta
   112801 cgccagtcct aaacttgctg aagtaggagt tacaaaaagt cacgcctctt cgtcagatca
   112861 agtggtagag atggatctta ccagttggtt cacctatcat cgtgtcaatg aaccagttgc
   112921 taaggctgaa ttgacctttg accagcaaaa ttatttgatt ggtgctgcag tgattagcga
   112981 gcaagcagac gaattgatcg atgatttgac actcgtcatc aatcaaaaat tgactaaaaa
   113041 agagttggat agctatatca tggggtatcc gacattggca agtgatctct cctatttatt
   113101 gaaataatca gcatgataac taaagcgctt gttgcttttt ccttcttgtg ctacacttta
   113161 aaaaatgaat acctgtttct ggggatgtcg tagacgacat gagagtaagt tgtgaactta
   113221 gacccattga acctgtcagt taatactggt gaagggagaa acatagcaga cgcttgaagc
   113281 gggttactat gtcgtgccca tttcaagcgt tttttgttat tcatattaga agaaaggagg
   113341 taacaaaatg aagaaaaatc tttatccagc agtcagtatg gcattcattt taattatttg
   113401 gcagattgtt gtcatagttt ggaaaatacc tgcctttatt ttacccggac ctgctgctgt
   113461 attttctgca ttagcggcag atgcacaagt attactttcc cattctgtca cgacattaaa
   113521 tgaagcagtg cttggtttgg taatagctag cgttctttct tttattactg ccttggcaat
   113581 ggattattgg aagtttttag aaatgtcttt ttatccgtta ctagtgattt cacaaatgtt
   113641 gccaatcatg gtgttagggc cattacttac cctatggttt ggtttcggta tgcttccaaa
   113701 agtgatcctt gttgtcttga taagctattt tccgatcgta gtttcttttt cggatacatt
   113761 gaggaaagta tcaaaagagc aaatcatctt tttgaaaacg atgggggcag atacagggaa
   113821 gatttatcga atatataaaa taccagcggg tttatccggc ttcttttccg gtttaaaagt
   113881 ggctgctact tattgtgtca gcggagcagt cgttggagaa tggctaagcg ctcaagcagg
   113941 cttagggtat tacatgatac gcgtaaaaaa cagctaccag atcgataaag tttttgctgc
   114001 gatcatttgt gtcattctat tgagtttatt gctgaatggc gcttgttcat tattgaaaaa
   114061 agggtattat cgtatgcttt atatttttta agagaagggg atcaaatgaa aaaattatgg
   114121 cttttattac cgctactgtt gcttttatcc gcttgtggca ctgcaaaaga aacaagtagc
   114181 aaacaagaaa taaaggattt gaaaaaagtg acacttgttt tggattatgt accgaatact
   114241 aatcatactg gcatctacct agcaaaagaa aaaggctatt ataaagaggc tggtttaaat
   114301 gtccaaatca tcgaaccagg agataattcg acaagtattg gtctagtagg tgcggacaaa
   114361 gcacaatttg gtgtaagtta tcaagaagat gtcacttatg ctcacgcaga tggacagaat
   114421 ataccagtca aagcaattgc tacagtgatc aaacataata cttctggatt cgccacccta
   114481 tcagacagta acatccattc accaaaagat tttgaaggaa aaacatatgc aggttggcaa
   114541 agtccaagtg aagaagctgt cttaaaagct gtgatggaaa aagacggcgg ggacttttca
   114601 aaactgacaa tggtaggaag caatggagaa gggccagaaa gcttaggaaa atcctcagat
   114661 atccaatggt actttgaagg ttgggatatg atcaaagcaa aagaagcggg tattgaacta
   114721 aactatatcc cattgaaaga attagatgaa cggttagatt actatactcc ggtaattatt
   114781 acgaatgatc aactgatcaa aagtgatcca gaattggtac agtcttttat ggatgccacg
   114841 aaaaaaggct atcaggaagc tattaaggat ccaaatgaca gtgctaaact gttgcaaaaa
   114901 tatgcaaaag aaaatgatcg gacgttttta gaagaatcac aagcattctt gtcaaaaaat
   114961 tatacggatg atcctgagaa ttggggattg atggaagaaa aagtttggcg caattataca
   115021 gcttttatgc aggaaaacgg attgatcaag caagatgtac cttcgcaaga actattcact
   115081 aatcagttta taaaatagga gtgatagata tgtcaatcca aatcagccac ttgaatgtag
   115141 tcattgaaaa cctgaaaata ttagaagaca tccatttcac tatccctaaa gataccttta
   115201 catcgattgt cgcgccaagc ggagccggta agtcaacatt gctgaaaact ttaacaggag
   115261 tccagcctat gacttctgga acgatcaaag tagacgatca aaaagtaact ggtctccata
   115321 cagcatttag ttatatgccg caagaagata tgttacttcc ttggctgagc gtctatcaaa
   115381 acgttacgtt atatcaaaaa atcaatcatc taacaatcaa tgaagaacaa gtaagggatt
   115441 atctggatat ctttgggtta aacggctatg aacatttttt gccggaacaa ttatctggcg
   115501 ggatgaagca gcgaacggcc ttgttacgaa caatcatgaa tccttcttct tacttgcttc
   115561 ttgatgaacc atttggagcg ttagatgcta tgaccagagg gcagatgcaa gactggatgt
   115621 tgaagctgcc taaaaaagca aagcggacta ctttacttgt gacgcatgat atcgaagaag
   115681 caatttattt atcagacagg attcttgtgc tttccgcccg tccggcacat gtgattgctg
   115741 agattcaagt gcctgaaaaa cgacggtcac gtgaatggct actgcagcaa tcagagttga
   115801 agcaaacgat ttatcagtta ttggcaggtg aattagatgt taagtgatgc tcattgtcat
   115861 ttagatggga gtcagagttt agcactcctt cagcaggaac acacgatttt gacgatcatc
   115921 aattgtgatt cgccagaaga atggaaggaa aacagacagc ttgcagcaag taagactcaa
   115981 gccttaagtt acggtatcca tccttggaaa gcagatagct atacgtttga acaagttgag
   116041 ccttttttga aaaaagcaag gatcatcggt gaaatagggt tagataatat ttggacgaat
   116101 gtaccgatga ctacacaaaa aaaagtattt gagcgacagc ttgcttttgc agccataaat
   116161 gagaaacctg ttgtactgca cacaaaagga tgcgaaaaag agatcttaaa ttatatccaa
   116221 gcttacccta atcactattt gatccattgg tattcttctt tggactatca acaagactat
   116281 attgatttag gctgttattt cagcattggt cttgatttga aaaagaatcc agcagtctgg
   116341 caactagcta aagcagtccc aatcgaccac ttacttattg aaacggatgg actacatgca
   116401 gcagagtggg ctttaggggg gattttttca gaaaaagatt atgtctcact gcttgaagaa
   116461 cagttaaaga caatcgctga gatcaaagag ctatcagttg aagaagttaa aaaaaatact
   116521 tatcaaaact tggaacgttt cattagatta ggtaaataaa aaagagatgt gacacaacta
   116581 gtgtcgcacc tctttttggc tttctttgta taaaagtaaa ctgtttgatt aataaatgaa
   116641 tcttagtacc aaccgtttgc ttcccagaat gctttcgccg cttcccaaga accataacgt
   116701 gaagtaacat attgttctgc tactctttct tggtttgcag cagagtagtc accatttaag
   116761 taagaagaat ctaattggta acgtccgatg taacgtccgt tcgttgctgt gtaagaaccg
   116821 cttgattctt tttgtgcgat ccattctttt gcagagcttg tgcttgctgg agtagcagca
   116881 gtttctgtta cagcaggagc aggttgtgtt tcagcaacag gcgctgcttg tttttccgtt
   116941 tgaaccgttt cttgtacaac aggttgttca gcttggactg gtgcttcttg aacggctgct
   117001 tgaggttcag cagctgcttg tgcagagcct tctgttggga ttgttaattg ttgtcctgag
   117061 ta
//
LOCUS       DAYYEF010000003       106951 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000003 DAYYEF010000000
VERSION     DAYYEF010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 106951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.003"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            212..604
                     /locus_tag="ACHA1B_000239"
     CDS             212..604
                     /locus_tag="ACHA1B_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFM8701037.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ACHA1B_000240"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ACHA1B_000240"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004356 - glutamine synthetase activity
                     [Evidence IEA];
                     GO_process: GO:0006542 - glutamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HFM8701038.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            2698..2943
                     /locus_tag="ACHA1B_000241"
     CDS             2698..2943
                     /locus_tag="ACHA1B_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701039.1"
                     /translation="MKEKDCFYDKLYKLLLQVGKSSSLLGGILSIIMFVLFFYLLFHL
                     KFFSNDFLICLGLTLAMFISSLLCGLNFFCTHKGLKK"
     gene            3165..4775
                     /locus_tag="ACHA1B_000242"
     CDS             3165..4775
                     /locus_tag="ACHA1B_000242"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003883 - CTP synthase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HFM8701040.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(4752..4964)
                     /locus_tag="ACHA1B_000243"
     CDS             complement(4752..4964)
                     /locus_tag="ACHA1B_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701041.1"
                     /translation="MKMKIFKKFFAKNKISNSALIEKSLLLSIFFPTNNNKSEKEKSD
                     KKIAYPLLLLLFSFYQVQKLFCFVIC"
     gene            5067..5936
                     /locus_tag="ACHA1B_000244"
     CDS             5067..5936
                     /locus_tag="ACHA1B_000244"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004332 - fructose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HFM8701042.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="ACHA1B_000245"
     CDS             6101..7372
                     /locus_tag="ACHA1B_000245"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFM8701043.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="ACHA1B_000246"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="ACHA1B_000246"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008186 - ATP-dependent activity, acting
                     on RNA [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HFM8701044.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="ACHA1B_000247"
     CDS             8763..9026
                     /locus_tag="ACHA1B_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HFM8701045.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="ACHA1B_000248"
     CDS             9471..9920
                     /locus_tag="ACHA1B_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM8701046.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="ACHA1B_000249"
     CDS             9977..11395
                     /locus_tag="ACHA1B_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HFM8701047.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="ACHA1B_000250"
     CDS             11395..12255
                     /locus_tag="ACHA1B_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFM8701048.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="ACHA1B_000251"
     CDS             12429..13202
                     /locus_tag="ACHA1B_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFM8701049.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="ACHA1B_000252"
     CDS             13349..13714
                     /locus_tag="ACHA1B_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HFM8701050.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="ACHA1B_000253"
     CDS             complement(13862..15070)
                     /locus_tag="ACHA1B_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM8701051.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="ACHA1B_000254"
     CDS             complement(15089..15367)
                     /locus_tag="ACHA1B_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701052.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15560..16216
                     /locus_tag="ACHA1B_000255"
     CDS             15560..16216
                     /locus_tag="ACHA1B_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFM8701053.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(16658..17455)
                     /locus_tag="ACHA1B_000256"
     CDS             complement(16658..17455)
                     /locus_tag="ACHA1B_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HFM8701054.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="ACHA1B_000257"
     CDS             complement(17452..18636)
                     /locus_tag="ACHA1B_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HFM8701055.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="ACHA1B_000258"
     CDS             complement(18661..19908)
                     /locus_tag="ACHA1B_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFM8701056.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="ACHA1B_000259"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="ACHA1B_000259"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HFM8701057.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="ACHA1B_000260"
     CDS             21888..22202
                     /locus_tag="ACHA1B_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HFM8701058.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="ACHA1B_000261"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="ACHA1B_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination mediator RecR"
                     /protein_id="HFM8701059.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /gene="tmk"
                     /locus_tag="ACHA1B_000262"
     CDS             22887..23531
                     /gene="tmk"
                     /locus_tag="ACHA1B_000262"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004798 - thymidylate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006233 - dTDP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HFM8701060.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="ACHA1B_000263"
     CDS             23546..23875
                     /locus_tag="ACHA1B_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HFM8701061.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="ACHA1B_000264"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="ACHA1B_000264"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HFM8701062.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="ACHA1B_000265"
     CDS             24863..25687
                     /locus_tag="ACHA1B_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HFM8701063.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="ACHA1B_000266"
     CDS             25680..26027
                     /locus_tag="ACHA1B_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HFM8701064.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="ACHA1B_000267"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="ACHA1B_000267"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0000451 - rRNA 2'-O-methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HFM8701065.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="ACHA1B_000268"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="ACHA1B_000268"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HFM8701066.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACHA1B_000269"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ACHA1B_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043365 -
                     [formate-C-acetyltransferase]-activating enzyme activity
                     [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HFM8701067.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACHA1B_000270"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ACHA1B_000270"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008998 - ribonucleoside-triphosphate
                     reductase (thioredoxin) activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HFM8701068.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31684..32451
                     /locus_tag="ACHA1B_000271"
     CDS             31684..32451
                     /locus_tag="ACHA1B_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701069.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="ACHA1B_000272"
     CDS             32441..34483
                     /locus_tag="ACHA1B_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8701070.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="ACHA1B_000273"
     CDS             34764..34913
                     /locus_tag="ACHA1B_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HFM8701071.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="ACHA1B_000274"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="ACHA1B_000274"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047473 - D-alanine [D-alanyl carrier
                     protein] ligase activity [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HFM8701072.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="ACHA1B_000275"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="ACHA1B_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0070395 - lipoteichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HFM8701073.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="ACHA1B_000276"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="ACHA1B_000276"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0036370 - D-alanyl carrier activity
                     [Evidence IEA];
                     GO_process: GO:0019350 - teichoic acid biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HFM8701074.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="ACHA1B_000277"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="ACHA1B_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070394 - lipoteichoic acid metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HFM8701075.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="ACHA1B_000278"
     CDS             39330..40412
                     /locus_tag="ACHA1B_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HFM8701076.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="ACHA1B_000279"
     CDS             40412..41215
                     /locus_tag="ACHA1B_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFM8701077.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="ACHA1B_000280"
     CDS             41285..42025
                     /locus_tag="ACHA1B_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFM8701078.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="ACHA1B_000281"
     CDS             42036..43040
                     /locus_tag="ACHA1B_000281"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017118 - lipoyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HFM8701079.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="ACHA1B_000282"
     CDS             complement(43085..44929)
                     /locus_tag="ACHA1B_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701080.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45140..45658
                     /locus_tag="ACHA1B_000283"
     CDS             45140..45658
                     /locus_tag="ACHA1B_000283"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFM8701081.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45786..46469
                     /locus_tag="ACHA1B_000284"
     CDS             45786..46469
                     /locus_tag="ACHA1B_000284"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HFM8701082.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46778..46851
                     /locus_tag="ACHA1B_000285"
     tRNA            46778..46851
                     /locus_tag="ACHA1B_000285"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46812..46814,aa:Arg,seq:tct)
     gene            47010..47369
                     /locus_tag="ACHA1B_000286"
     CDS             47010..47369
                     /locus_tag="ACHA1B_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HFM8701083.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47492..49123
                     /locus_tag="ACHA1B_000287"
     CDS             47492..49123
                     /locus_tag="ACHA1B_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HFM8701084.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49185..49826)
                     /locus_tag="ACHA1B_000288"
     CDS             complement(49185..49826)
                     /locus_tag="ACHA1B_000288"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFM8701085.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50012..50088
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50108..50416
                     /gene="rplU"
                     /locus_tag="ACHA1B_000289"
     CDS             50108..50416
                     /gene="rplU"
                     /locus_tag="ACHA1B_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HFM8701086.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50443..50787
                     /locus_tag="ACHA1B_000290"
     CDS             50443..50787
                     /locus_tag="ACHA1B_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HFM8701087.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50800..51093
                     /gene="rpmA"
                     /locus_tag="ACHA1B_000291"
     CDS             50800..51093
                     /gene="rpmA"
                     /locus_tag="ACHA1B_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HFM8701088.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            51527..54334
                     /locus_tag="ACHA1B_000292"
     CDS             51527..54334
                     /locus_tag="ACHA1B_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFM8701089.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            54525..55016
                     /locus_tag="ACHA1B_000293"
     CDS             54525..55016
                     /locus_tag="ACHA1B_000293"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFM8701090.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            55119..56108
                     /locus_tag="ACHA1B_000294"
     CDS             55119..56108
                     /locus_tag="ACHA1B_000294"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose/fructose/sorbose PTS transporter subunit
                     IIB"
                     /protein_id="HFM8701091.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            56141..56944
                     /locus_tag="ACHA1B_000295"
     CDS             56141..56944
                     /locus_tag="ACHA1B_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HFM8701092.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            56965..57879
                     /locus_tag="ACHA1B_000296"
     CDS             56965..57879
                     /locus_tag="ACHA1B_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFM8701093.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            57962..58336
                     /locus_tag="ACHA1B_000297"
     CDS             57962..58336
                     /locus_tag="ACHA1B_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HFM8701094.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            58475..58720
                     /locus_tag="ACHA1B_000298"
     CDS             58475..58720
                     /locus_tag="ACHA1B_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFM8701095.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            58892..59956
                     /locus_tag="ACHA1B_000299"
     CDS             58892..59956
                     /locus_tag="ACHA1B_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M24 family metallopeptidase"
                     /protein_id="HFM8701096.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            60202..60627
                     /locus_tag="ACHA1B_000300"
     CDS             60202..60627
                     /locus_tag="ACHA1B_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFM8701097.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            60620..61069
                     /gene="nusB"
                     /locus_tag="ACHA1B_000301"
     CDS             60620..61069
                     /gene="nusB"
                     /locus_tag="ACHA1B_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HFM8701098.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            61166..62020
                     /locus_tag="ACHA1B_000302"
     CDS             61166..62020
                     /locus_tag="ACHA1B_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HFM8701099.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            62021..63358
                     /gene="xseA"
                     /locus_tag="ACHA1B_000303"
     CDS             62021..63358
                     /gene="xseA"
                     /locus_tag="ACHA1B_000303"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA];
                     GO_function: GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA];
                     GO_process: GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HFM8701100.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            63363..63587
                     /locus_tag="ACHA1B_000304"
     CDS             63363..63587
                     /locus_tag="ACHA1B_000304"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HFM8701101.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            63589..64479
                     /locus_tag="ACHA1B_000305"
     CDS             63589..64479
                     /locus_tag="ACHA1B_000305"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFM8701102.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            64488..65306
                     /locus_tag="ACHA1B_000306"
     CDS             64488..65306
                     /locus_tag="ACHA1B_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HFM8701103.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            65413..65862
                     /locus_tag="ACHA1B_000307"
     CDS             65413..65862
                     /locus_tag="ACHA1B_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFM8701104.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            65880..67562
                     /gene="recN"
                     /locus_tag="ACHA1B_000308"
     CDS             65880..67562
                     /gene="recN"
                     /locus_tag="ACHA1B_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HFM8701105.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(67617..67733)
                     /locus_tag="ACHA1B_000309"
     CDS             complement(67617..67733)
                     /locus_tag="ACHA1B_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HFM8701106.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(67806..68762)
                     /locus_tag="ACHA1B_000310"
     CDS             complement(67806..68762)
                     /locus_tag="ACHA1B_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFM8701107.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            68933..69301
                     /locus_tag="ACHA1B_000311"
     CDS             68933..69301
                     /locus_tag="ACHA1B_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HFM8701108.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            69471..69902
                     /gene="mraZ"
                     /locus_tag="ACHA1B_000312"
     CDS             69471..69902
                     /gene="mraZ"
                     /locus_tag="ACHA1B_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HFM8701109.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            69923..70882
                     /gene="rsmH"
                     /locus_tag="ACHA1B_000313"
     CDS             69923..70882
                     /gene="rsmH"
                     /locus_tag="ACHA1B_000313"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HFM8701110.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            70887..71288
                     /gene="ftsL"
                     /locus_tag="ACHA1B_000314"
     CDS             70887..71288
                     /gene="ftsL"
                     /locus_tag="ACHA1B_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HFM8701111.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            71289..73481
                     /locus_tag="ACHA1B_000315"
     CDS             71289..73481
                     /locus_tag="ACHA1B_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFM8701112.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            73507..74469
                     /gene="mraY"
                     /locus_tag="ACHA1B_000316"
     CDS             73507..74469
                     /gene="mraY"
                     /locus_tag="ACHA1B_000316"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008963 -
                     phospho-N-acetylmuramoyl-pentapeptide-transferase activity
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HFM8701113.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            74483..75844
                     /gene="murD"
                     /locus_tag="ACHA1B_000317"
     CDS             74483..75844
                     /gene="murD"
                     /locus_tag="ACHA1B_000317"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HFM8701114.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            75870..76958
                     /gene="murG"
                     /locus_tag="ACHA1B_000318"
     CDS             75870..76958
                     /gene="murG"
                     /locus_tag="ACHA1B_000318"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050511 -
                     undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HFM8701115.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            76973..78193
                     /locus_tag="ACHA1B_000319"
     CDS             76973..78193
                     /locus_tag="ACHA1B_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HFM8701116.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            78349..79674
                     /gene="ftsA"
                     /locus_tag="ACHA1B_000320"
     CDS             78349..79674
                     /gene="ftsA"
                     /locus_tag="ACHA1B_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0043093 - FtsZ-dependent cytokinesis
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HFM8701117.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            79697..80938
                     /gene="ftsZ"
                     /locus_tag="ACHA1B_000321"
     CDS             79697..80938
                     /gene="ftsZ"
                     /locus_tag="ACHA1B_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HFM8701118.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            80955..81632
                     /locus_tag="ACHA1B_000322"
     CDS             80955..81632
                     /locus_tag="ACHA1B_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HFM8701119.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            81646..82245
                     /locus_tag="ACHA1B_000323"
     CDS             81646..82245
                     /locus_tag="ACHA1B_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HFM8701120.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            82326..82547
                     /locus_tag="ACHA1B_000324"
     CDS             82326..82547
                     /locus_tag="ACHA1B_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HFM8701121.1"
                     /translation="MVYALLSWFPGGYQSGLGRLLAKICEPYISLFDRLPLRIGPLDF
                     TILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            82596..83378
                     /locus_tag="ACHA1B_000325"
     CDS             82596..83378
                     /locus_tag="ACHA1B_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HFM8701122.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            83399..84106
                     /locus_tag="ACHA1B_000326"
     CDS             83399..84106
                     /locus_tag="ACHA1B_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HFM8701123.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            84368..87166
                     /gene="ileS"
                     /locus_tag="ACHA1B_000327"
     CDS             84368..87166
                     /gene="ileS"
                     /locus_tag="ACHA1B_000327"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004822 - isoleucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006428 - isoleucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HFM8701124.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(87215..88741)
                     /gene="zwf"
                     /locus_tag="ACHA1B_000328"
     CDS             complement(87215..88741)
                     /gene="zwf"
                     /locus_tag="ACHA1B_000328"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004345 - glucose-6-phosphate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HFM8701125.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(88756..89403)
                     /locus_tag="ACHA1B_000329"
     CDS             complement(88756..89403)
                     /locus_tag="ACHA1B_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFM8701126.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(89587..89916)
                     /locus_tag="ACHA1B_000330"
     CDS             complement(89587..89916)
                     /locus_tag="ACHA1B_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HFM8701127.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            90093..90821
                     /gene="sfsA"
                     /locus_tag="ACHA1B_000331"
     CDS             90093..90821
                     /gene="sfsA"
                     /locus_tag="ACHA1B_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HFM8701128.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            90837..91850
                     /locus_tag="ACHA1B_000332"
     CDS             90837..91850
                     /locus_tag="ACHA1B_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFM8701129.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            91850..93127
                     /locus_tag="ACHA1B_000333"
     CDS             91850..93127
                     /locus_tag="ACHA1B_000333"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFM8701130.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            93190..95892
                     /locus_tag="ACHA1B_000334"
     CDS             93190..95892
                     /locus_tag="ACHA1B_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFM8701131.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            96044..96361
                     /locus_tag="ACHA1B_000335"
     CDS             96044..96361
                     /locus_tag="ACHA1B_000335"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM8701132.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            96391..96711
                     /locus_tag="ACHA1B_000336"
     CDS             96391..96711
                     /locus_tag="ACHA1B_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFM8701133.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            96819..98279
                     /locus_tag="ACHA1B_000337"
     CDS             96819..98279
                     /locus_tag="ACHA1B_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFM8701134.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            98347..98568
                     /locus_tag="ACHA1B_000338"
     CDS             98347..98568
                     /locus_tag="ACHA1B_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701135.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            98599..98781
                     /locus_tag="ACHA1B_000339"
     CDS             98599..98781
                     /locus_tag="ACHA1B_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HFM8701136.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            98781..99194
                     /locus_tag="ACHA1B_000340"
     CDS             98781..99194
                     /locus_tag="ACHA1B_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HFM8701137.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            99317..100498
                     /locus_tag="ACHA1B_000341"
     CDS             99317..100498
                     /locus_tag="ACHA1B_000341"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8701138.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(100569..100733)
                     /locus_tag="ACHA1B_000342"
     CDS             complement(100569..100733)
                     /locus_tag="ACHA1B_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701139.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            100887..100960
                     /locus_tag="ACHA1B_000343"
     tRNA            100887..100960
                     /locus_tag="ACHA1B_000343"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100921..100923,aa:Arg,seq:cct)
     gene            complement(101029..102168)
                     /locus_tag="ACHA1B_000344"
     CDS             complement(101029..102168)
                     /locus_tag="ACHA1B_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8701140.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            102340..102474
                     /locus_tag="ACHA1B_000345"
     CDS             102340..102474
                     /locus_tag="ACHA1B_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701141.1"
                     /translation="MIKVIFKRITELPEFRLFVDYWYVWFFIVALLIGLDVILERKLK
                     "
     gene            complement(102467..103102)
                     /locus_tag="ACHA1B_000346"
     CDS             complement(102467..103102)
                     /locus_tag="ACHA1B_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701142.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(103215..103850)
                     /locus_tag="ACHA1B_000347"
     CDS             complement(103215..103850)
                     /locus_tag="ACHA1B_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HFM8701143.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(103884..104345)
                     /locus_tag="ACHA1B_000348"
     CDS             complement(103884..104345)
                     /locus_tag="ACHA1B_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4429 domain-containing protein"
                     /protein_id="HFM8701144.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(104475..104906)
                     /locus_tag="ACHA1B_000349"
     CDS             complement(104475..104906)
                     /locus_tag="ACHA1B_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFM8701145.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(104924..105244)
                     /locus_tag="ACHA1B_000350"
     CDS             complement(104924..105244)
                     /locus_tag="ACHA1B_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8701146.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            105543..106319
                     /locus_tag="ACHA1B_000351"
     CDS             105543..106319
                     /locus_tag="ACHA1B_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HFM8701147.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            106334..106537
                     /locus_tag="ACHA1B_000352"
     CDS             106334..106537
                     /locus_tag="ACHA1B_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8701148.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            106553..106891
                     /locus_tag="ACHA1B_000353"
     CDS             106553..106891
                     /locus_tag="ACHA1B_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HFM8701149.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
BASE COUNT        34910 a        18262 c        22358 g        31421 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaatttat cgttattata tgattaagaa ggattgaata
    45121 aagaaagaag ttgaaaacga tacctgatta caaaaaaata acttttataa gttctataac
    45181 gttgattata tttttaattc ttattcttct cgtcgtcttg gttccccgaa tttttggttt
    45241 gactccttat attattgagg acaaagaaat gagtccatat tatgcacaag gaaatctgat
    45301 atatgtacga ccgaaaaata caaatgagat tttagtcgga gatattatta catattatga
    45361 aaattcagga aaaaaaatct cgacgcgtcg cgtaatagcc gttgaaaaca accacgaaga
    45421 tttttataca aaagctgata caaagactta tattgagcct ggagtagtaa aaaagagaaa
    45481 tattatcggt agtcccatct ttcagattcc atatattgga ctagtccttt caaaaacggc
    45541 atttgcatgg attcaggggt tattctttac gattgctttt tgcctaacag gaatcacagc
    45601 atggaatacc tttgtagagt tgaaaaagaa gcggagacga acacagaaat ttttgtaaga
    45661 atgttaaaaa cataaatgta ttccagagat ccaacgactc ttctgaacat gaaacacgag
    45721 aaaacactca tgcagcttgt agatttagtc agttgttcgt ataatgtgtg aagaggagga
    45781 gtagtatgcg caatgaaatg atgcatcgtc ctgtagtcaa agaagaacta ttggatttta
    45841 tgcgtaccca gcaaaaaaaa ttaccgggtg agctaggcaa actggaagaa gaagctcatg
    45901 tagcagaagt accagttatt ccccatgaaa cagttgtatt tttgaaattt ttacttggac
    45961 agcttcagcc tgaacgaatc ttggagatcg gagcagctat cggtttttca tcaagtgtca
    46021 tggccacgac aatcggagaa aacgctcatg ttacgacaat tgatcgtttc gatgtcatga
    46081 tcgagaaagc taaaaaaaac tatgaacgtc taggactgac agataaagtg actttgcttg
    46141 aaggtcaagc agcagatatc ttgccggagt tgtctggtcc gtatgacttt atttttatgg
    46201 atagtgcaaa atcaaaatat attgaatttt tacctgaatg cttacgtttg ttaagaaaag
    46261 gtggcgtttt gatggtagat gacatcttcc aaggaggaac gatcttgctc ccagatgaag
    46321 agattccccg tggcaaacga gctatccatc gtaaattaaa tgaatttctt cgtgttgtga
    46381 tggatcatcc cgatttgaca tcgacaatct tgccattagg tgatggtgtg atcttaatga
    46441 caaaggaatc agaaacaatc gagttgtgat acatgattat ggcagcctgt agataatcga
    46501 ttgaatcgag ggctcaattc gaacttgatg taaaagtttc tatatttgta agtcaattaa
    46561 aggatacagg aaatctaaat aaacaggagt agcatgaagt caatgtagct cctgttttca
    46621 attgataacc ttagaacagc tgaaggagaa tgtctcgttt taaaagattg atttagtagt
    46681 tgggccaaaa taattcatta tttgctaatt aaataactat ttcgtattga cagaagcaat
    46741 ttaattatct ataattattg atgttccgct gattcttgtc atagtagctc agctggatag
    46801 agcatccgcc ttctaagcgg acggtcgggg gttcgaatcc ctcctgtgac gctaaaaaac
    46861 cgttagaaac tgaggtttct aacggttttt ctttgttttt tgtgccaata ttgtttgttt
    46921 tcaaaggcaa ataaaataaa aaaacatcct tatcgagtac aattataagg agcaaaaaaa
    46981 taaaactcat cagaaaagag gaagaagata tgacgatact atctagaatt ttagtgactc
    47041 tagttgcaat tgaatttttt tatatcatgt atatcgaaac ggtgagaact gattctgaca
    47101 cgacaagtag ggtttttaaa atgagtaaag aagagttaag cagaaaatct gttcaaacat
    47161 tgtttaagaa ccaaggagtg tacaatggac tattaggagt gggactactt tatggagctt
    47221 atctttcttc cgcatctaaa gaaatcacaa gtatgctatt aatatctatt ttttttgttg
    47281 cattatatgg cagtttgact agcgatcgtt ggattttact caaacaaggt gggctagctc
    47341 tgttggcatt gctttctatt ttcttataaa tatagaaaaa ataagaattt atctaacagg
    47401 aaactttgtg aaaaatatta ctttatctca tgaaatatga tattctaatg aatggtattt
    47461 tagaaaattt catgaaaaag gagttagata ggtgttcaaa aattatgttt cctcactaaa
    47521 aaaagaattt tcaggttatg atctttcaag atttcagaaa gatcttttgg ctgggatcac
    47581 agtagctgct gtagcattgc ctttagcctt ggcttttggg gtatcaagcg gagctgatgc
    47641 ggccgcaggt ttgattacgg ctatcattgc cggtatcgtt attggcggtt tatcaggcgg
    47701 tttttatcaa atatcaggtc cgacaggtgc gatggcagct atcttgatgt ctattgcggc
    47761 aacaaaggga atgcaaggtg tattgcttgc tactttttta gcgggtctat ttttacttgc
    47821 agcaggactt ttccgattag gaacactgac ttcttttatc ccagcacccg taattacggg
    47881 gtttacttca ggtattgcta tcattattgc attaggtcag atcgataatt tatttggtgt
    47941 tcactcggaa ggtacaaacg ttattgaaaa actaagtagt tatcaaacga taggatttcc
    48001 gataaacaca gcctctttga tcatgggagg gctagtcatt ttagggatgt ttatctatcc
    48061 aaaaaaatgg gcgaaacgaa tgcctagttc gctgctggct atcattttgg caacagcagt
    48121 tatgctattg ttccatttac cagtagcaac tgtgggtaag attccacaaa cattgatcag
    48181 tagtaatcgt ttgaatatgg gagattttag cttttctgcc ttgcaacaag tggcagttcc
    48241 agctattagc attgctttat taggaatgat tgaaagcttg ctatgtggtg cttcggctgg
    48301 ccgaatggca aataagccct tagatagcaa tcaagaatta atggcgcaag gaattggaaa
    48361 tctgttgctt cctttctttg gcgggattcc tgctactgcg gccatcgccc gtacaagcgt
    48421 ggccatcaaa tctggtgcac aaactagatt agctggtatg atacatgcag ttgtcttact
    48481 gctctccatg cttgtttttg cgccagtgat gtcacagatt ccaatgccag cacttgcagg
    48541 tgttttgatt gtgacggctt ggcgtatgaa tgaatgggaa acgatcaagg agctatttac
    48601 taataaatat tggtcagcag ttctattgtt tatccttacg atgatttgta cagttatctt
    48661 tgatttaagt attgctatcg tgatcggggt gatcggcggc tgtgtatttt ttgttgtcaa
    48721 aagcgctgct atcacgattt cattagaaac gatcgattgg caaagaatgg ggctgccaga
    48781 aacggaaaag ctgaataact ggacagtagt gtatattagt ggtccactgt tttttatgtc
    48841 ttcagaaaaa ctcaaaaata aattggaaga actaaatcat cacgatggtg tcattttctc
    48901 catgcgaggc gtaccaagta ttgatttgac ggcacgtgca gtttttgatg aatttcaaga
    48961 aaaagcagag caaagaggac aaacgattat ctatacttcc ttgcagccag aagtagaaaa
    49021 acaactttct cacttgtggg aacatacatt cacgcatcaa catcaaacag ttgctcatgc
    49081 gttgacagct ttacatgcga aatatactgc aattagccat taaaacaatg aaaaagaaca
    49141 gacaagactg taaactgaag attttatggt cttgtctgtt ctttttaata ttgctgtaaa
    49201 agtgaagcta gtacttgcca gtcttgatgg ataacaggta caagggagcg attgtagaaa
    49261 atagctgctg gatgaaaaag tggaagaatt cgatagtttt tttctgacca ttcgtaggca
    49321 tccttttgtt ctgttaattg taagacaggc cctgtataga gttgaccatg atttttggta
    49381 accgtatatt ctttgccaag taaacgttga agaccaatgt ttccaagtgt cgcaattaat
    49441 tttggctgga ccttcatcag ttcgtaatcc aatattggtg catgcgcaaa tacttcggaa
    49501 cgagtaggtg tccgatttgg ataaacagtt tctgactgtt gtgtccgttt attgatccga
    49561 tgagtcacgc gatacgggcg gctccttaca gcactggtga tatacacctc ttctcgtgtt
    49621 aagccagttg aagaaagtgc ctgcatcaat tcttttccag cttgaccgct aaaaggaaca
    49681 tgcgtatcaa tctctgtttt ccctggggct tctcccacga gcatcagttt aggatgaaga
    49741 ggtccttgcc cagcgataaa tccttctaca ggacggccgt tcattcttaa agaagcttct
    49801 tgtatcagtt cttttgggta ttccatttat gctcctcctt tttcttttat tataagaata
    49861 aaagaaacac aatgcgacta ttttatttgg tagaactgtg aggatagaaa agcagaagta
    49921 ttgcttgaat ttttgtttta ctttttgatt ttaaatttag ttgactaacg gttgctgttc
    49981 tggtaagcta gtactgttgt aattgtggac tccacagcta caaccgctca gaacaagtaa
    50041 taagcacagc atatgctgtc acttcggatg gcgagtctaa gtatatcaga aggaggtgct
    50101 ttatagcatg tacgcaatta ttaaaactgg tggtaaacaa gtaaaagttg aagtgggaca
    50161 agcaatctat gttgaaaaac ttgacgttga agcaggagaa aaagttgttt ttgacgaagt
    50221 tatcttagta ggcggagaat ctacaaaagt aggcgctcca actgttgcag gtgcaactgt
    50281 tgaaggtact gttgaaaaac acggcaaaca aaagaaagtc gttactttca aatacaaacc
    50341 taaaaaacat tcacaccgta aacaaggtca tcgtcaacca tatacaaaag tggttatcga
    50401 cgcgatcaac gcttaatagc gtttgagaaa gaaggcctat atatgatcaa aggaacattt
    50461 aagcgaaatg acgcaggtca gatcgtttca ttcactttga ccgggcatgc tgatgctggt
    50521 ccttatggaa gtgatatcgt ttgtgcgggt gtttctgcgt tagcgatcag cactgtcaac
    50581 gggattgcct cattagccgg ttttgagccg attgttgaaa tgaatgaaga agaaggcggt
    50641 tatctttata ccgaagtcac ttcaggaatg acacaagaac aaaacaatat tgctgagatt
    50701 ctattagaaa atcttttatt aggattacaa tcgatagaag ctgaaaactc agaatatatc
    50761 caaattaaaa caattaatga taaataggag gtgcagacca tgttgttatc tatgaatcta
    50821 caattatttg cccacaaaaa aggtggcggt tctacatcta acggccgtga ctcagaatca
    50881 aaacgtctag gtgctaaacg tgctgatgga caaacagtta caggtggatc aattctttac
    50941 cgtcaacgcg gtacaaaaat ctatccaggt gtaaacgtgg gtatcggtgg agacgacact
    51001 ttatttgcaa aagttgatgg cgtagtacgt ttcgaacgta aaggccgtaa caaaaaacaa
    51061 gtgtctgttt atccagtagc tcaagaagct taattgaatc ttatgattaa agaggttgtg
    51121 acaagacttt tgtcacagcc ttttttgttt ataaaaataa aagttgtagt ggaggctacg
    51181 aagtttactt tgtcttttta cacttaatat ttttttgcca atttggaatc aggatgtttt
    51241 gataactatc gttttcaatt gatggaagct atattgtttg ctatcagtga aataattata
    51301 tggtaaacag tgttcttttt cttgtttcca ttataaaaat cgtatcggga tttttcgttc
    51361 ttttaaattg aacatttcta tctatccgcg tgttatcaac aaaacaaaat caggtaaata
    51421 gttgacgaaa cagaaataaa tacatagtat tatgttttga agcctaagta caatagtcta
    51481 tagaaaagga gcgataccat tggcaaaacg cattgaccga atttatatgt atgtcaaaga
    51541 aaaaaccgct catttaacaa aggcagaata tgatcaagga gtaacaacac aggaaattgc
    51601 tgaagtgtta gggattcagc gaacaaatag cagtaaagat ctgaatcagc tagtgcgcga
    51661 aggaaaactg ataaagacag acggacgacc agtacgttac atatatcaaa cactcgttac
    51721 gcacgtaaag ccagttacaa aacatgtagt cagttacaaa gaaacgccgg tctctgaaga
    51781 aaaaaataca ctccaaatag atactaagga tatctttgca aaaatcattg gagctaacgg
    51841 cagcatgaaa aattcagtgg aacaggcaaa agctgcgatt ttgtatccgc caagaggatt
    51901 aaattgtttg attacaggac ctaccggatc aggaaagact tattttgcac acgcgatgta
    51961 tcattttgca aaagcgcatc atgtaataga tgaggaaacg gaactgattg ttttcaattg
    52021 tgctgattat gccaataacc ctgagctttt gatgagtcat ttatttgggt acgcaaaagg
    52081 tgcttttaca ggcgcagatg aagaaaaaat ggggattatc gatcaagcgg atggcggtat
    52141 gctgtttttg gatgagattc accggttgcc gcctgaaggt caagaaatga tcttttactt
    52201 tatggatcat ggaacttaca gtcgtcttgg ggaaacaacg aaatcccatg aagcaaatgt
    52261 acggatcgta ggtgcgacca cagaagaccc aggttcttct ctattagaaa cttttgttcg
    52321 gcgtatccca atcaatatca aacttccggc ttttgaaaaa cgtcctgcaa atgagaaagt
    52381 cgatttagta aaaatcatga ttgcccacga agcaaaccgc acgcagcgaa agatttcttt
    52441 gacagaagat gtagcaaaag cattgatcgg cagtgtgacc tatggaaata taggacaatt
    52501 gaagtcaaat atccagttag tatgtgcacg aggatttcta aatcatatgc aatcacccga
    52561 aatctcgatc acaatcgatg atttgacaga agggattcgt agcggattga ttcaattagc
    52621 aagcaaccgc agtgcaatgg cagagctttc taaaatattg gagccaaaga taactgtagc
    52681 accaaatgat acgatcatga aaatccaatc ggactcctat gagttacctt ataatctata
    52741 tgatatcatc ggagataaag cagctttact gaagtcggat ggtttggatc aagaagcaat
    52801 caatcatttc atttctacag atatcaacat ccatctgaag tctttctata aagaccatgg
    52861 tttttctttt aatgcagaca gcaaattagc agaatttgta gatccgaaaa tcatagaagt
    52921 gaccaatcag atttatgtaa tggtcaaaag atctttacca tatgagtttc agcaaaactt
    52981 tatttatgct atgagcttgc atatcagttc ttttttgaaa aaaatcaact taggagaaga
    53041 acggcatacg aatgataaca tccgtgagat ggcttttgat tttccagatg aatatgctgt
    53101 tgcgaaagaa gtgcgtagtt atatcgaaac gtattttcaa gtggagattc cagaaagtga
    53161 agactattac ttgaccgttc tactcgtctc gttacgggca aatcaagcaa gcggcagaat
    53221 cggtgtagtc gttgcagctc acggaaacag cacagcaagc agtatggtcc aagttgtcca
    53281 acagttgtta gatgcagaga acgtacgagc agtagacatg cctttggata tggatccgaa
    53341 aacagcattg gaccgaattg aacgcaatgt acaagaagta gatgaaggaa gcggggtcat
    53401 actcttagta gatatggggt cccttgcgtc gtttaattcg caaattcaaa gagacactgg
    53461 aattccagta cgtactgttg atatggtaac aacttctcta gttttggaaa ctgtacgaaa
    53521 ggtctcagta ttagggacag atctagatat gttgcatgaa tcattgaaaa attttcgagg
    53581 ttacgcagaa atatcttctg tagaatctgt tcaggaagca aaacctattc ataagaaaaa
    53641 agctgttttg gctatctgcg catctggcga aggtacagca caaagaatca aagaattgat
    53701 cgaacgagcg gtaaacaagc gtcaagaaac agaattagaa gttctagctt tgtcgattgt
    53761 ggaagtgaaa gaagaactgc cagttatcca aaaagaatat cagatcatag ctactactgg
    53821 gattactgat ttgaatatcc aagccccatt tattccttta gaacgtttta ttgatcaaaa
    53881 tatcgaagtc attttggatc agttgctgat ggaatcagaa ttggaggaaa ctgaattcat
    53941 ctccctagat gaagagtcag ctaaaaatac gtgtgttgag tttatctctg ataacttcat
    54001 ctttattaat ggtagtaagt taatcgatcc aatgtggcaa ttttctacac aaatctctca
    54061 gacgacggga atcggcgatg aagaatatgg attcaaaatc aacctagtga tgcacacagc
    54121 aggaatgatc gaacgtatta ttcggaatga accattgact gtggaagaaa acgaattgac
    54181 aaatacaacg aatgatcctc tttatagcca attggcagcc tcagttgttc tgttggaaga
    54241 tcagataaaa gtaaaagtgc cgatagaaga aatgtattat ctgctacgtc tagtccataa
    54301 tcagttagat aaaaaagaat acactgtgcc atgaatacac aaaaacgata cacttttata
    54361 gtgtatcgtt tttgtgtatt ggttaagaat cctttaaatt caattagtgt atcgtaaaaa
    54421 agttggcacg ctttttgctt atagtagtgt gtgctaggag gtggttgttc acacagaaat
    54481 gataggggtt tctgtgaagt agtgaggaag aaggagtttt gcagatggat attcgattgg
    54541 cacgtataga tgatcgttta atccacgggc aagtcgcaac agtttggtcg aagcaaacag
    54601 gtgttgaacg tatcattgtg atcagcgatg tagtcgctca agataaattg agaaagtttc
    54661 tactaaaaga agctgcaccg ccggggatca cagcaaatgt aataaccgtg cagaaaatga
    54721 ttcaaatcta tcatagtgga ttattatcac gagcaaaagt gatgctttta ttcaccaatc
    54781 cccaagatgt tgaagcggtt gtccgctgcg gtgtacagtt gaagtcgttg aatatcggcg
    54841 gtatgagttt tactgaaggc aaatcaatga ttaccaattt tgtttcagta aatcaacaag
    54901 atattgattc ctttcgttac ttgaacagtc aagaagtgga gttagagatt cgaaaagtac
    54961 ctgctgacag gaaaatcctt ttgatggaac tactagcgaa aatcaaaaag gtgtagcaag
    55021 aatggttgtt ggaaaaggtc aaataattct gttgtaatgg ttagcaatta ttaatatttt
    55081 tgaatttgtt acaacaaaag taaataggag gtataaatat ggtagggatt atcctagcaa
    55141 gtcatggaca atttgctgaa ggaatcttac aatccggttc aatgatcttt ggcgaacaag
    55201 aaaacgtcaa agccgtgatt ttgaaaccaa gtgaaggtcc agatgacttg agagccaaat
    55261 tggaagaagc ggttgcttct tttgataatc aagacgaagt gttattctta gttgatttat
    55321 ggggcggaac accgttcaat caatcaaaca cattattcga agagcacaaa gataaatggg
    55381 caatcgtcag cggtttgaat ttaccaatgt tgattgaagc ctacgcatca cgcttttcaa
    55441 tggaatctgc tcatgaaatt gcagcacaca tcattgaaac agcaaaagac ggtgtaaaag
    55501 taaaaccgga agaattagaa ccggcagaag caccgaaagc agcagttgaa gacgcacaac
    55561 ctaaaggagc acttccagaa ggaactgtgg tcggagacgg aaaaatcaaa tatgtattag
    55621 cacgtgttga ctcacgtctg ttacatggac aagttgcgac agcttggaca aaagcagtgc
    55681 aaccaaaccg tattatcgtt gtttcagatg cagtatcaaa ggatgatctg cgtaagagac
    55741 taatcgaaca agctgctcct ccaggtgtaa aagcaaatgt tattcctatt agcaaaatga
    55801 tcgaagtagc aaaagaccct cgttttggaa ataccaaagc attgctttta tttgaaaatc
    55861 ctgaagacgt attgacagct gttgaaggtg gcgtagacat caaagaatta aatgttgggt
    55921 caatggcgca ttcggtcggt aaagtcgttg taagtaaagt attgtctatg ggacaagaag
    55981 acgttgaagc gtttgagaag cttgaacaaa aaggtgtgaa attcgatgta cgtaaagtac
    56041 ctaatgattc acgcgataac atggatgata ttttgaaaaa agcaaaagct gaattagcaa
    56101 aagcgtaata aataatatta aaatttatag gaggcttatc atgtctatta tttcaataat
    56161 tttagtcgta ttagttgcct ttctagctgg tatggaaggt attcttgatg aatttcaatt
    56221 tcatcaacca ctagtggcat gtacattgat cggtttagtt accggtaacc tcgaagctgg
    56281 tatcgtactt ggcggtacgc ttcagatgat cgctttaggt tgggcaaata tcggtgccgc
    56341 tgtagcacca gatgctgcat tagcatcagt agcatcagca attattttag ttttaggtgg
    56401 acaaggtgtt aaaggtgttc cttctgcgat cgcgattgcc gttcctttgg ctgttgcagg
    56461 gttgttctta acaatgatcg tacgtacaat cgctgttcca atcgttcatt tgatggatgc
    56521 ggctgctgaa gaaggaaaca tccgtaaggt tgaaatgtgg cacatcattg ctgtatgttt
    56581 acaaggggtt cgtatcgcgg tcccagcagc agcgttgcta tttatcccag cacaaactgt
    56641 gcaatcattc cttgaatcaa tgccagcatg gttaacagat ggtatggcta tcggtggggg
    56701 aatggtcgta gctgtaggtt acgctttggt aatcaacatg atggctacaa aagaagtatg
    56761 gccattcttc gttattggtt tcgttgtagc tgcaatttct caattaacat tgattgctct
    56821 aggtgcttta ggtgttgcat tagctcttat ttacttgaac ctttctaaaa tgggtggttc
    56881 atcaaataat ggaggcggaa gcaactctgg tgacccttta ggcgacattt tgaatgacta
    56941 ttaatcttga aggaggaaaa taaaatggca gaagaaaaaa tcaaattatc aaaaaaagat
    57001 cgtttagctg ttgcgtggcg ctctaccttc attcaaggtt catggaacta cgaacgtatg
    57061 caaaacggtg gctgggcatt ttctatgatt ccagcaatca aaaaattata caaaacaaaa
    57121 gaagaacgtt ctgcagcatt aaaacgtcac ttggaattct ttaatacaca cccatacatt
    57181 gcttctccaa ttttaggggt tacattggct ctggaagaag aacgtgcgaa tggcgcgcct
    57241 gttgatgatg tagcgattca aggggttaaa gtaggtatga tgggtccttt agctggtgtt
    57301 ggtgacccag tgttctggtt tacagtacgt ccaatgctag gtgcactagg tgcttcatta
    57361 gctatgggag gaaatatcct tggaccaatc atcttcttct taggttggaa cattattcgt
    57421 tgggcattca tgtggtatac acaagaattt ggctacaaag ctggttctaa aattactgat
    57481 gacctttctg gcggattgtt acaagacgta acaaaaggtg cttcaatttt agggatgttc
    57541 gtattagctg cccttgtaca aagatgggta tcaatcaaat tcttaccagt tgtatcaact
    57601 gtaaaattag ataaaggtgc ttacatcgaa tgggataaat tgccttcagg tggtgaagga
    57661 atcaagagtg catttgaaca agttaataat ggcttagccc tttctcctga aaaggtaaca
    57721 acattacaag acaacttaga ccaattgatt cctggtttag ctgcattagg attaacattg
    57781 ttatgtatgt ggttgcttaa gaaaaaggtt tctccaatcg ttatcatcct tggtttattc
    57841 gtagtcggcg ttgttggaca cgtcatcgga cttttataat ccataaaaat atagctcggg
    57901 cgttgtcccg agcttttttt atatagtata ctgttcataa acaaatatct ggagggagaa
    57961 aatggttcaa tcaatcaata caaaagtaga cttggtaatt gatgctactt cgtttacggg
    58021 tctgacagat tacgggcaaa tcatgatagg taataatggt tttgagtttt accatgcgcg
    58081 agatagacgc aaatatatcc aaattccatg ggaagaagtg gattatgtac tagcatcagt
    58141 catgctaaag ggaaaatgga ttcctcgata tgccattcaa acgaaaaaaa atggtacata
    58201 cacattttct tccaaagaac ctaaaaaagt gcttcgtgcg atcagagaat atgtagatga
    58261 agatagaatg gtacaatcat tgagtttctt tgatgtagtg aaacgtggta ttcgtagtat
    58321 gtttaaacgc aagtaaaaaa taaagaaaac ttctaagagg aggttttctt tattttttta
    58381 ctttgcagaa gaaaatatga aatagcaaaa ccaattattt gtccccttta aatcccatat
    58441 gctaaaattg attagcaaag aaggaggtta tattatgagt tggttatgga cattgattgt
    58501 tggagccgtg atcggagcaa ttgcaggtgc gatcaccagt aaaggaaatt cgatgggctg
    58561 tgtaacgaat atcattgctg gactagtcgg ttcaagtatt ggacaagcga ttttcggcga
    58621 atggggacca aaagctgcag gtatggcact tattccatct attttaggcg cagtgatttt
    58681 ggtagcagtt gtctcatttt tctttggaaa acgatcataa gtttttacaa aatagtaaac
    58741 taaaaggagt tgcagcgaga ctgtgactcc tttttggctt tatttattta aaataaaaag
    58801 aagttttccg gaaattttta tttaactgtc gtgtacgaag aaaagtttgc tataatggaa
    58861 aaaagcgtgc aaagaaagag ggagtttcat tatgatgcta cgtgtagaaa aattgcgcaa
    58921 aaaaatgcaa gaagaaaatt tggattcatt tttggttacc agtccgtaca atcttcgtta
    58981 cttaacgaac tttacaggta cgacaggatt agctgttatt actttggaaa aagcattttt
    59041 tattactgat tttcgttata ccgagcaggc ggcagcgcag gctcaagggt ttgaaattat
    59101 taaaaatgtc ggacctattt ttgatgaggt agcaaactta gtacgcaaag aagaactgca
    59161 ctcattagct tttgaggaaa caacagtctc atttttagaa tattcggttt tagaagaaat
    59221 catcgatgcg gaattagtac ctgtttcaca gatgatcgaa gaactcagag aagtgaaaga
    59281 tgaagaagaa atcgctatta tcgaaaaagc atgtcatatt gcggatatgg catatgatca
    59341 catcctgaaa atgatccaac cgggcatgac tgagattgaa gtcgcaaatc aactagactt
    59401 ttatatgcgt tctcttggcg cttcaggtgt ttcttttgat acgatcgttg ctagcggatt
    59461 gcgttcggct atgccgcatg gtgtagcaag caaaaaaatc atcgaacaag gtgacttgat
    59521 cacattggac tttggttgct attacgaagg gtacgtttcc gatatgacac gtacattcgc
    59581 tattggtgat cctggggaaa aattaaaaga aatttatcaa atagtcttag atgctcaatt
    59641 agcagttatt gatgctgcaa aaccaggaat gactggtgtc caattagatg cagttgctag
    59701 agattatatt tcaaaacatg gttacgggga agcatttgga cattctacag gacatgggat
    59761 cggtttagag atccacgaag gaccaaacgt ttcttctcgt gcagaaaagc aatttgtacc
    59821 aggaaatgtg atcactgatg aaccagggat ctacttacca ggaatcggtg gagtacgtat
    59881 tgaggatgac ttgttgatca cagaagatgg aaatcgtgtg ttgactcgtt caccaaaaga
    59941 attgatcatc ttatagtttc atcaatagaa gaagtaagcg taaaaatcag tgttcacaga
    60001 ctttgttata gaaaatcact cgatttaatg atacactata gaagaacttt taagctgtaa
    60061 gagataataa agttgggtgt tttctccaat tcatagcagt ttgcagctga tcggcggcag
    60121 ttttcttacc acgtgatcac tatgccgcat catagagaat tcggatgtat ctcgtgctta
    60181 ggcaaaggga ggaataaata aatggcagat gaaaaaaatt tgattttaaa cgcaaaccaa
    60241 gatttaggag agatcgtgat cgctcctgaa gtcatcgaag taattatcgg gattgcagct
    60301 tctaaagtag aaggcgtata cggaatgcgc ggaacttttg ccagcaatgt cactgaatta
    60361 ttaggacgtg cagctcacgg aaaaggtgtt tacttagcaa acgaggaaga tggcttgaaa
    60421 gtagatcttt actgttatct agaatatggt gtttcagttc ctaaagtagc aatggaaatg
    60481 caggaacggg tcagccagca agtccttttc atgacggata tcgatttatc tgaagtcaat
    60541 atccatgtag tagctgttgt tcctgaaaaa ttagaacaac caacaatcga agaacttttt
    60601 gaagacgaag aggaagagaa tgaataaaga attatcaaga cacgagattc gggaaatggc
    60661 attgcaggct ttatttccat tagacttcaa tgcagaccta acaaaagaag atgcgatttt
    60721 caacgcaatc gaattagacc accgcgacat gatcaacgaa gatgaatcag agtttgttcc
    60781 tgtttatctt gatacgctag ttggcggtgt ctgtgcaaaa aaagatgaat tggataaagt
    60841 gattgaaaaa catttaaaaa acaattggca catcaatcgg atctcaaaaa tggatttggt
    60901 gatcttgcgt atcgcgattt ttgaaatgac ttatgtgaca gatgtaccag cggctgttgc
    60961 tttaaatgaa gcaatcgagt tggcaaaaac atttagtgat gaccgttcac gtaaattcgt
    61021 caacggtgtt ttatccaatg tattgaaaga attagaagct ggggcgtaag tcctagcttt
    61081 tttctatgaa tcatcataaa cctgttataa atcgggaaaa ttctatggta gaatgaaaac
    61141 acaaaaaata tctgggagtg gttagatggc agaattgatt aacggaaaag aattagctga
    61201 aaaaatgcag gcagagattg ctgaaaaaat ccaaaaattg aaagataatg gtatccatcc
    61261 cggattagtc gttttattgg taggggaaaa tccagccagc caaatctatg taagaaataa
    61321 agaacgtgta gcaaaagaaa tcggaatcca ttcattggta gagcgttatc ctgagacgat
    61381 ttctgaagac gaactacttg cagaaattga aaaatacaat caagatccta gttttcatgg
    61441 tatattggtc caattaccat tgccaaagca tatagatgaa gaaaagatcc tgttagctat
    61501 ccgccctgaa aaagacgtag acggttttca tccgatgaat ttaggcagac tccttgcggg
    61561 taaaccggac aagattcctt gtactccata cggcatcatg aaaatgtttg aagcttattc
    61621 tatcgatccg gcgggtaaac gagcagtagt tatcggacga agcaatatcg tcggtaaacc
    61681 gatggctcag ctactcttga tggcagatgc aactgttact gttgctcatt ctaaaaccga
    61741 aaatctggct gaactggcac aagaagcaga tattttagtc gtagcaatag gacgtggaca
    61801 ttttgtcaca aaagaattcg taaaaccagg tgctgtagtg atagatgtag ggatgaatcg
    61861 tgatgctaac ggtaagctga tcggtgatgt gaaatttgat gaagtggagc ctattgcagg
    61921 ctggatcact cctgtgccaa agggtgtagg gccaatgact atcacgatgc tgatgtatca
    61981 aaccgtaaaa tctgccgaag cttttggagc aggtgaatag atggcacaag aatatttaac
    62041 tgtcactaca ttaacgaagt atttgaaaag aaaatttgat gccgatcctt atttagaacg
    62101 cgtatattta acaggcgaaa tatcgaattt ccgtttacgt gccaatgccc atcaatattt
    62161 cagcttaaaa gatgaccatg caaaaatatc tgctattatg ttcaaaggag cattccaaaa
    62221 attacgattc cagccaaaag aaggaatgaa agtccttgtc gttgggcgta tttcattata
    62281 tgaagcggga ggttcttatc aaatctatgt agagcacatg gagcctgatg gaataggtgc
    62341 tttatatcaa gaattggaag aacgaaaaga aaagctgatg aaggaaggcc tttttcaagg
    62401 gcctaaaaaa atgctgccac gtttcccaaa gcgaatcgcg gtccttacca gtccaagcgg
    62461 agcggttatc cgcgatatca tcacgacggt gaaaagaaga tatccaattg tccaattggt
    62521 tttgttccca acagttgtac aaggaaacca agcagcggac aatgttgtca ggaatatcca
    62581 gagagtagaa gagatgggca atttcgatac aatgatcatc ggtcgtgggg gtggttcgat
    62641 tgaggattta tggccgttta atgaagagcg ggttgctcgg gcgatttatc aagctaatac
    62701 gccggtgatt tcatctgtag gacatgaaac agataccacg atcgctgatt tagtagcaga
    62761 tgttcgggct gccactccaa cagcagctgc agaattagct gttcctgttt tgtcagaaga
    62821 gttgatgcgc attcaagaac ggcaagctag attgcagcag gcgtttgtac gccagatcca
    62881 gcgcaaacaa gaacggttcg agcgtgctcg acgttcctat gtatttcggc agcctgaaag
    62941 attgtatgaa ggtcagacca tcaaattaga ccagttgaaa cagcgattat atcaagctac
    63001 acagcaaatt tatcatgcga aagaaaaaca aacgatcgca ttaagccacc aattggaaca
    63061 agtggctccg ctttatcgag ttaaagcagc tcgccaagaa actgcttatc tagaaaaacg
    63121 cttagaagag aaaatccaac aatatatgaa acaacagcag cagcgttttg ctcaagctgt
    63181 tcaatctctt gatttgttga gtccattgaa aatcatggga agaggctaca gctatacgac
    63241 gttaaatgat caagtagtaa aaagtgtcac cgagattcat caaggggatt tgctgacgat
    63301 ccattatcaa gatggaatcg ttaaaggaca agtacaagag atagacaaag gagaataaaa
    63361 atatggaaaa tccaactttt gaagagtcac tgcaagaatt agaaaaaatt gtcatgcagt
    63421 tagaacaagg agacgttcca ttagaatcag ctctagattc gtttaaacga ggaatggaat
    63481 taagcaaaca ttgccaagat acattagcta aagcagaaga gaccttgacg aaaatgatga
    63541 cagaatcaaa tgaagaagtt gattttgacg gaaacgagga aagctgagat gagattaact
    63601 gacttttcag ctattcatct acctgctgta gaaaaagaaa tcttgtcttt tttagatgag
    63661 catacaacgg atagaggact ctatgatgcg atgagttatt cagtgaaagc aggcgggaaa
    63721 agaatacgtc ccttattact tttaacggcc gttgcttcct ttgatgagcc tattgatgtt
    63781 cccgtctatc aagtagcagc tgctttagaa atggtgcata cgtattcctt gatccacgat
    63841 gatttgcctg cgatggacaa tgatgatctt cgtagaggaa aacctaccaa tcataaagta
    63901 ttcggcgaag cattagctat attggccgga gatggtttgc ttacaggagc attccagcta
    63961 atcagtatgg cacacttagg taattctcct aagcttctgc tgcttcagca attagctgtt
    64021 tgtgcgggat cacaaggtat ggttgctggg caagctgcag atatcgaggg cgaatcgaaa
    64081 aagctttctt tagaagaatt agcatttatt catgaaagaa agacagggca tttgattcgt
    64141 tatgccttgc tggctggtgg catattagcg aagcaacctg aagaaatctt attgctactt
    64201 caacgattag ccgaacattt aggtttagct tttcagataa gagatgatct actcgatgtg
    64261 attggtacaa cgaaaacatt agggaaaaca gctggtaaag atgaacgtat ggaaaaaaat
    64321 acttacccgc gtttattagg cctagaaaag acacgtgagg cgttggagat tgagctgtta
    64381 tccgccaaca agatcataga caaattagaa gaggacgttt tttcttttga tggcgggctg
    64441 atgcgccaga tgatcaagca atttgatgtg gagaaatgag ggaaagaatg gaaaaagaac
    64501 gcgtagatgt attagcggtc aaacaaggat tatttgaaac aagagaacaa gccaaacgtt
    64561 cagtgatggc tggtttgatt tacaacgaaa aaaacgagcg gtttgataaa ccgggagaaa
    64621 aaattccagt gagtagtgaa ttaagagtca aaggtaaaaa acttccttat gtttctcgag
    64681 ggggattaaa attagaaaaa gcactcaaag catttgatct atctgttgaa ggaaaaacat
    64741 tgttagatat tggtgcatcc actggcggat ttactgatgc agctttgcaa aatggcgcaa
    64801 aaatgagtta tgctttagac gttggctaca atcagctagc ttggaaaata agacaagatc
    64861 ctagagtcgt cgtaatggaa agagtgaatt ttcgttatgc aaaacccgaa gactttacct
    64921 taggaattcc agaagttgct gttatcgatg tttcttttat ttcactaaaa ctgatgctgc
    64981 ctccattaca tgctatttta aaagaagagg gagaagtgat tgctttaatc aaaccccaat
    65041 tcgaagcagg cagagaagct gtagggaaaa acggaattgt tcgtgaccct cagacccatc
    65101 aaaaagtttt agaagacatt ttgtcatttg cggcacaagg tggatatgat gtgctggaat
    65161 taagttattc tccgatcacg gggggagaag gaaatatcga gttcttggct cacttgagga
    65221 aagtacccga aagcggaaca atcaattcag ctattaatat ggcagaagtg gtttcaaatg
    65281 cacacgaaca gtttgaccat aaataaattg taactgtgaa aatcaagtga gaagtatgcg
    65341 gattcttctt tattatacca aggaaataag ctatcattga ttaagaagaa tatgctaagg
    65401 agcgaagacg taatgagaaa aaaagatcgg catcgtttga ttactcgatt gttgagtgag
    65461 caagatatcc gaaagcagga agaatttgtt gaaatcctga aaagcaaagg aatatctgtt
    65521 actcaagcta cgatttccag agatataaag gaactgaaac tgatcaaggt accggcttca
    65581 gatggcggct accgttatag cataccagct gaaacaaacg aagatgtaaa tactaaattg
    65641 gaaaaactat taaaagacgc tttcgtggca gttgaccaaa tggaaaaatt tgttattttg
    65701 aaaacattgc cgggaaatgc ttcggcagca gcaaatttga ttgataaacg ttacaagaaa
    65761 gaattatttt cgattatcaa tgatgacgat aatgttttga tgattacacg aactgaagac
    65821 caggcagttt tattgaagaa agacttcctg cattaccttt aagttgagga gcgaatgtga
    65881 tgctacaaga aatcagtatt actaactttg cgattattcc ggaattgcgg ctttcttttc
    65941 acgaaggaat gaccgcgctg accggagaga ctggtgcggg taaatccatt attatcgatg
    66001 ctttaggtct gttagcagga ggaagaggtt caagcgatta tatacgtcaa ggagcagaaa
    66061 aatgtgtgct tgaagggttg tttgaactac caaaacaaga aggattctct gaactgatgg
    66121 ttgaattagg gatcgaaaca gatgaggaca atctgattgt tcgacgggat atgtccttaa
    66181 ctggaaaaaa tgtttgtcga gtgaatggtc atattatcac attagctaat ctgagaagaa
    66241 tcggcagtta tttagtagat atccaaggac aaaacgaaca tcaggaactg ctccagcctg
    66301 aatcacatct tgctttattg gatcgttttg gagatgtagc tttccaacag aagaaaaaga
    66361 gttatcagca agaatatatc tcttatcgtg agctggaaaa aagggtacga aaagtgcagc
    66421 aaaatgaaaa atcctatgtt cagagaatag atatgctcca tttccagcaa gaagaaatag
    66481 ctgctgctga tttgcaagtc ggagaagaag agaaattaaa agaagaaaga gaaaaactta
    66541 gcaattatca aaaaattgct gatggattag ctgcaggtta cggagcactg acgaataatg
    66601 aacaaaacag tgtagatggt gttggcttgg ccgtttcaga actgcaaggg atcgcccatc
    66661 tagatgtgga gtatgaagca atttatgaaa atatccaaag tgcttactat ttgctgcaag
    66721 atgcaatcgg cgatatgagt cgtcagattg atttattgga gttagatgag agtcgtttag
    66781 aagaagttac gcaacgttta gaattaatcc gacagttgaa acgtaaatac ggcgaatcca
    66841 ttgagtcaat attggcttac tatgacgaaa tcaccgaaga gctagcttct tctgattttt
    66901 cagaaggtca attggacaaa atgaaagagg aactagagca aaaagagctt ctacttcagc
    66961 aacaagccgc agatcttcat gaagcgcgta aaaaaatcgc aaaagaattg gaaaaatcca
    67021 ttctgcatga attgaaaagt ctgtatatgg aaaacactga gtttgaggta cgtttcttaa
    67081 aagaagaaaa tagacaattg aatcatgatg gatttgacca aatcgaattt tacattacga
    67141 ccaatccagg agagccactg aagcctttgg tgaaagtcgc ttctggtggc gaactgtctc
    67201 ggatgttgct tgctttgaaa actatttttt cttctgagca aggtgtgaca agtattattt
    67261 ttgatgaagt ggatacaggt gtgagcggaa gagttgcaca ggccatcgca gataaaattt
    67321 ctcaaatatc gaaatactct caagttttgt gcatcactca tctgcctcaa gttgctgcag
    67381 tcgccgacta tcaatattat attgtgaaag cagtgattga tggacgtacg caaacttctg
    67441 tttcagagtt gaaaacaaaa gaaagagaag aagaaattgc acgtatgctg gctggaagtg
    67501 agattacaaa actcacactc gaacatgcaa aagaactatt gaaactcgca aaaaggacct
    67561 gagccacctc gcagtggttc aggtcctttt cagcagctga tagctatatt ttatttttac
    67621 atgacactca ttacagcagt caatacaaca gatccaatcg ttaaaatcag cattgtccaa
    67681 atgacaaatt ttgttacttt agcaaaagta cttgtttgtt ttttttcacg cattgttttc
    67741 aacctcgtca ttaattagtt gattcaagtg tacaatcttt tttccatttc cacaagaggg
    67801 cttttttata aaaacttccc tttttttaaa taataggtag ttacgataca aataaataat
    67861 gttaatagaa ctagccatat aaaggcatca tccctttcag caataggtaa cttaatgttc
    67921 attccataga tactgccgac gattgtcggt atagttaaaa taatcgttaa agaagttaaa
    67981 attttcataa tattattcag attattcgat acgattgctg aaaaagtctg attcatttgt
    68041 tctactagtt ttaattgaat gcgagaagta gtcattgcct gctctgtttc caccaataca
    68101 tcacgtaaat gatttttcaa agcatgattt tcttggaaaa gtttattttg cgctagttct
    68161 ttcaatgcat ctaaattagc agaagtcgct tctctgaaat aaacgaggct tttttggata
    68221 tccatgattt gataaagttg tttgttttca gtggatactt gaagtttggc ttccaaagta
    68281 tcgcattgag attgaagcgt agctaaataa ctgttgtaag agagtgtgac ctgccaaatg
    68341 aattgaaaga agatattgag attaggcgaa atatcacttt ttggaaaggt ctggctaaag
    68401 actttcttta aaaacagtgg ttcatgattc gtaattgtga taagcttctt tttgggcgtc
    68461 aaaataatag agagcgggta tgtatccact tgaaaataac cgctaggact tgttttagca
    68521 aaaggatatt gtaacaataa taacgctggc tttgtcaact ttgattgatt gaattcttct
    68581 gtacgggaat tttctgcatc gtccaatatg gaagtgatgt aatctgacgg aatttcaaat
    68641 tgatgtgtca gctgatgaat ctcttcttga ttaggacgtt ctacacaata ccagatcgtt
    68701 tggtcagttt cctttccggt attacgcagt ttctcattat ctaatgtaaa atatttgatc
    68761 atgattttcc tcctgttgcc tgtttctttt attataacgg atagggaatt ggaatacatg
    68821 gaatgtgttt gtaagatata gaatataact gcataaattt aaataaaatg aaacagttgt
    68881 gtaaagtata tacagtatac ttgaagcaac gataaaaaag gagtttacgt tcatgggcac
    68941 attcacacca cttatcttgt tttggtatat ttacccggta atcgttttgt ttggttgcca
    69001 atttcttgta aaattatttt cgttaaatcg tcgttttaaa ataaaagccc ctgatttggc
    69061 gattcctttt ttgtggggcg gtatgcatgc attgtctaga aatacaggga caatttctat
    69121 cttaccgttt ttctttattt ctgttttgct aatgggaatt tgtattgctg ttttccaagc
    69181 atattattat gaagaaatta tttatccgcg ttatttcaag atgacttggc gtttggtttt
    69241 tctgttgaca atcgtcttgt acgctgtctt gatcattgtg aacatacttt cttacctatg
    69301 aaaaaaatag aaaagctgta aaaagtcttt taaaaggctt tttgcagctt gatttttaaa
    69361 aaaatgttta tgaataaaaa aagttgttcc cggatttccc agaaaaggtg gtagaaagtg
    69421 ggggattgtg gtagactaat tttagttagt ggaggaatgg ggggctttca atgttgatgg
    69481 gtgaattcca acataatatt gatgcaaaag gacgtttaat cgtgccctca aaacttcgtg
    69541 aagaacttgg cgaaaagttt gttctgacac gcggattgga tggctgtctt ttcggctatc
    69601 cgatgagcga atgggaaaat ctggaagcta aactgaacga aatgccgttg gctaaaaaag
    69661 acgcacgtac ttttgtgcga ttcttctatt cggctgccac tgaatgcgaa cttgataaac
    69721 aaggacgaat caatataccc agcacgttaa gaaattatgc agctttgaca aaaggttgcg
    69781 tagtcatcgg tgtatctaac cgaattgaaa tttgggatga gacacgatgg caagattttt
    69841 ctgcagcagc agaagagaac tttgacgaaa ttgctgaaag tatgattgat ttcggactat
    69901 aagaatagga agaggctgac taatgactga aacatttcaa cactatacag tcatgttgaa
    69961 agaaacggta gatggattga acatcaaacc ggatggcgtt tatgtagact gtacactcgg
    70021 cggtgccgga catagtgaat atttattaag ccaactaagt tctaaagggc atctgtatgc
    70081 gtttgaccaa gatcaaaaag caatcgatca cgccaagctg cgtttagctt cttatgtcga
    70141 acaaggtatg gtcacattta tcaaagcgaa cttcagagaa ttagaagaac gcttgagtga
    70201 gcatgtagat aaggtagacg gcattttgta tgatctaggg gtttcctctc ctcagctaga
    70261 tgaagcagaa cgtggattta gttatcatca agatgcaccg ttggatatgc gcatggatca
    70321 gtcagctcct ttatccgctt atcacgtaat taatgaatat tcctaccatg aattagtaaa
    70381 gattttcttc cgctatggcg aggagaaatt ttccaaacaa attgctcgtg aaatcgaacg
    70441 agtacgaaaa acaaaaccaa tccaaacaac tggtgagctt gtcgaaatca ttaaacaagt
    70501 catcccagct cccgcaagaa gaaaaggcgg gcatcctgca aaaagaattt ttcaagctgt
    70561 gcggattgca gtaaatgacg aactcggtgc cgaagaggcc tctttagaac aggcaatccg
    70621 gttattgaaa gtcaatggaa gaatcagcgt aatcacattc cattcattgg aagacagaat
    70681 tgtcaaaagt atgtttaaag aatatagtac ggtacaagat ctaccaccgg gacttcctgt
    70741 catacctgac gaattccaac cagaactgaa agtcattact cgtaaaccaa tccttccttc
    70801 agaggaagag ctaacagaaa acaatcgatc acgcagtgca aagttacgta ttgcagaaaa
    70861 aataagaatg aaagaggagt agaatgatgg cagaattaaa gaaaatgcaa gattacgaat
    70921 atgatttacc tgaattggtg gatcagccgg aacaacaaat gcctgattct tcttcgaatc
    70981 aagaaatcat tcttccacaa tcaccggcaa aacgattaaa gcagatttct gctttggaaa
    71041 aaattgctgt ggcaagcgtg gcgattgcta ttgttgcttt atgtgtttta acagttatgc
    71101 tgcgcacaaa tatcagcgga gctgaaaaag aaatcacgtc aatacaaaca gaaatcaatg
    71161 ataaaaagca agaaaaaacg agtttagaac aagaaaaaaa cgaactttct cgtactgaac
    71221 ggattaaaca aatcgcagaa gaaaaaggat tgtctattaa tgacgacaat ttaaggaaag
    71281 tgaagtaaat gagtcttaaa aataaaattc ggcggtttat ggaaaagaaa aatctaaatc
    71341 cgatgaacaa tcgcaaaaaa gtaggtatca ttttatttgc tacgagtatt ggattgttct
    71401 ttttatttgc cgtccgtttc tcgtatatcg ttattggagg tcatgttgct ggtacctcat
    71461 tagctgaaaa aacaaaacag ttgtaccaag gaagtgaagt agtaaaagca aaaagaggaa
    71521 cgatttatga tcgtaacggt gtggcgctcg cagaagatgc ctcctcttat tcaattaaag
    71581 cgatactctc aaaaacatat acctctgggg ataaaaaact gtatgttgaa gaaaagaatt
    71641 ttgataaaat agcagaaatc ctgcataaga atctttctat agacaaaaaa gatgcactga
    71701 atattttaga ggacggcgca aaaaaagagc tgtatcaagt tgaatttggt agctatggga
    71761 aaaatatctc ccaagaaacc aagcaaaaca tcgaagcgga catgaaaaaa gaaggtgtcg
    71821 ctggtcttta ttttgtcgac catcaggctc ggatgtatcc aaatggcgtc ttttcttctc
    71881 attttattgg atacgcagtt ccagacaaag atgagaatgg cttagttggt aaactaggtt
    71941 tggagtctgc ttacaatgat atcttgagcg gtaaagatgg taagattatt tatcaaaaag
    72001 ataattttca aaatcctctg ccaggtacag tggcagaaga agaaaaagct gtcgacggac
    72061 aagatatcta cacgacttta gacagcagac tacaaagtta tttagaaaca ctgatggatc
    72121 aagtaaatga agaatatcag ccagaagaat tgacagcagt cctgatgaaa gcaaaaaccg
    72181 gagaaatctt ggcaatggga caacgaccta ctttcaatcc tgaaacaatg gaaggattga
    72241 ctggaaaaga tgctatctgg cgtaatttct tggtacaaga tagttatgaa ccaggatcaa
    72301 ccatgaaagt tttcactact gcagctgcta tcgaagaagg agaattcaac gagaatgaaa
    72361 ccttccaatc tggaaaaatc caagtagaag atgctacgat caatgaccat gactttggtg
    72421 aaaaaggtgt gctgaccatg cgtcaagctc tttcatggtc aagtaacgtc gggatggtca
    72481 tactggaaca gcgattaggc ggacgatggt ataactattt acaaaaactg ggatttggac
    72541 aaagtactca ttctggatta gatgatgaag taaacggtgc tttacctaca ttaaatattg
    72601 tcgaccgagc aatgagtgct tatggacaag cggtaggtgt gacgaatttc caaatgatga
    72661 aagctttcac ttctattgcg aataacggta caatgattca acctcgatat atcagcaaag
    72721 tggtggatcc ccaaactgga gaagagcgaa caactcaaac agaagttcta gggcaacctt
    72781 tttcaaaaga aacaacagaa aaagtccgtg aatatatgag agatgttgtc gaaagcgaaa
    72841 actacggtag tgcttatggt gtatatagtg tacctggata caatgtatcg gcaaaaaacg
    72901 gaacagccca aatcgcttct gatacagggg gatatcaaac aggagataca gcctacctgt
    72961 attcgattgt ggagatggtt ccttctgaag atccagacta tgtcttgtat ctaacaatga
    73021 aacaccctaa gacatatgat cgaatggcat tggctaaaat cgcaaatcca ttgatgaaac
    73081 gggcaatgga ttttaaagaa actgaagaag attcagatac agaaacaaaa acagaaaaag
    73141 tatccgtagc cgattatcgt aatcttgaag cggacgttgc agcagctgat gctcaaaaaa
    73201 gtggactgca acctgtagtg atcggtaatg gtaaaaaagt acaaaaacaa tctactgcca
    73261 acggtgatca gttgatctct ggagaaaaac tgatcctata tactggtggt gataagctga
    73321 tgcctgacgt aacaggatgg tcaaaagcag atatcatgaa gctggggaaa atcctcggta
    73381 ttgaagttag ttttgatgga gatggttatt gtgtcaaaca agaacttgct ccatatgaaa
    73441 aaatcactga agacaaactt agttttactt tagaagaata agaagagaaa taggagagaa
    73501 aagagcatgg aatggacaca agcattgatt cccattgtca gcagttgtgc aatgacaatt
    73561 gccgcaatgc cgctatttat tggttatttt caaatgaaaa agcaaggtca ggcgattcgt
    73621 gaggagggac caaagtggca caatagcaaa gccggaactc ctacaatggg cggcttagtg
    73681 tttctgatcg gctctatttt gacaggaatt tgggttggag cttggcaaaa acagctaact
    73741 cctactcttt tcatcttgct ttttgtatta gcgttatacg gagtaatcgg ctttcttgat
    73801 gattttataa aaatattcaa gaaaagaaac atgggactga actcgaagca gaaattgatt
    73861 ggacagattc tagggggaat catcttttat cttgtttacc gttctgaagg ttatccaggt
    73921 gtattgaatt tcttcggact agatctacct ttaggaatca tttatggtat tttcgctctc
    73981 ttctggcttg ttggattttc aaatgcagta aatctgacag atggcatcga tggattagtt
    74041 gctggcttag gaagtatctc ttttgcagct tacggtctaa ttgcttggca tcagcatcag
    74101 tatgatgtat taatcatttg cttaagtgtt ttaggaggtt tactgggttt cttcgtctac
    74161 aacagaaaac ctgccaagat ttttatggga gatgtcggtt cattagcgtt gggcggactt
    74221 ttagcggcaa tttctataat gctaaaccaa gaatggacat tgcttttgat tggtttgatc
    74281 tatgttatgg aaacagcaag tgtgatgctt caagttactt cctttaagct tacaggaaaa
    74341 cgaattttta aaatgtctcc aattcatcat cactttgaaa tgtgcggatg gtcggagtgg
    74401 aagattgata cagttttttg gttgatcagc attgtgactt cgttgatcac attatggatc
    74461 gtttggtagg agatgacggg aaatgaaaaa aatatcaaca tatgaaaata agaaagtgct
    74521 tgtcttagga ctcgcaaaaa gcggagtaag tgcggccaaa ttattacatg aattgggcgc
    74581 acttgtcacc gttaatgatg gaaaaccttt tgacgaaaat ccggaagcac aagagctgct
    74641 ttctttaggg ataaaagtaa taacaggtag tcatccaatc gaattgttgg atgaagaatt
    74701 ttcattgatg gtcaaaaatc cagggattcc ctacagtcat cctttagtag caaaagccca
    74761 agaaatgggt attccggtaa ttacggaagt tgagctagct tacgaagtag cggaatgccc
    74821 aattattggg attacaggaa cgaacggaaa aacaacgaca acaacgatga caggactact
    74881 actgaatgca ggagcagatc aaggaattgc acgtttagcg ggtaatattg ggtatccagc
    74941 aagtggtgta gcgcaagaag caaaatcaga agataaaatt gtgatggaat tgtctagctt
    75001 ccaactcatg ggaatcacag atttccgccc tcatatagcg gtgattacca atatctatga
    75061 agcacatatt gattatcatg gtacaagaaa agaatatgtc aaagctaaat ggaaccttca
    75121 aaaaaacatg acagaaaaag attatctgat ccttaactgg aatcagtcag aactacaaga
    75181 attagcgcaa agaacaaaag cacgcgtact gcctttctcg acaaaagaag tgttggaaga
    75241 cggtgtgtat gctgacgatt actcaatata ctataaaaaa gaaaaaataa tggaaatatc
    75301 tgaacttggc gtaccaggta agcataatgt agaaaatgca ctagctgcta tttctgtagc
    75361 aaaattgtat ggtatatcaa atgaagctat acgagaaacg ttgcattttt tccatggcgt
    75421 accacatcgt acgcaatatg taggagaaat ccaaggcaga aaattttata atgattcaaa
    75481 agcaaccaat attttagcga ctaaaatggc tctaagtgga tttgaaacgt ctaaggtcgt
    75541 gttattggct ggcggattag acagaggaaa tacatttgat gaattaattc cttcattaaa
    75601 aggaatcaaa gcaatggtcg tatttggcca aacaaaagaa aagttgatgg atgctggaaa
    75661 aaaagcaggc atcgagacaa tagtaacagc cgattctgta gaacaagcag ttcctttagc
    75721 attagaaaac agtacagatg gtgatgtagt tttattatca ccagcgaatg ccagctggga
    75781 tcaataccca aattttgaaa ctagaggaaa cagattcatg gaagctgtga accgattaaa
    75841 atagaaaaag tagaagcgag cgataaaaaa tgaaaatttt ggttacaggc ggaggaacag
    75901 ggggacatat ttatccagct cttgcctttg tcaattatgt aaagactcaa gaaccgaatg
    75961 ctgaattcat gtatgtggga gcaaaacgag gtctagaaaa caaaatcgtc cctgatacag
    76021 gaatgccttt ccataccttg gagattcaag gatttaaacg aaaaatttcc atgcataaca
    76081 tcaagacggt ccgattgttt cttaagagta tccgtcaagc aaaaaaaatc ctcagtgatt
    76141 ttcaaccaga tatcgttatc ggtactggag gatatgtttc cggagcggta gtgtacgctg
    76201 cagccaaaat gggtattcca acagttatcc atgaacaaaa cagtgtacca ggtgttacca
    76261 ataaattttt aagccgatat gtggatcgga tcgctctttc atttaaagat gcggcttcct
    76321 tttttcctga aaacaaagca gttcttgtag gtaatcctcg agcacaagaa gtagcagata
    76381 ctaaaaaatc agatattttg aaaacatttg atttggatcc agaaaagaaa acagtcttga
    76441 tttttggcgg tagtcaagga gcacttaaaa tcaatcaagc agtatcagtt tttttaagtg
    76501 aatatattcc ttcttcttac caagttttgt atgcttcagg agatagatat tatgaagaga
    76561 tcctaaataa aataaatcct gaaatacaaa atattagtgt ccagccttat atcaaaaata
    76621 tggcagaggt catggcttcc agtgatctgc tggtggggcg tgctggtgca acttcgatcg
    76681 cagaattcac agctctgggg ttaccggcag tgttggttcc cagcccatat gttacgaatg
    76741 atcatcagac taaaaatgca atgagtcttg ttcacgcagg agcagcaaaa atgattgcag
    76801 ataatgaact aacaggtgaa tcactaagtc agacagtcaa cgaaatcatg ggtgatgaag
    76861 aattgcaaaa gcaaatgtgc cgagcttcta aagaacaagg aatccctgat gcttcaaaac
    76921 gtctttatga cttagtaaaa caaataatca aaaaataaag gcggtggtct tagtgagtaa
    76981 gaaaaaagaa ccaaaaaaat tgtctcatcc gtcttctgat gaaaacaatt tgactccttg
    77041 gcaaaaggct aaccgaaaat atctggcaga acaagagatg aaaaaccaag agccaaaaaa
    77101 agaagacata acattagata cacccctttc agattctgaa gaagaaaaaa cggttcaaga
    77161 ggaacagcaa gaagaaagcc agtccgagaa aaaaatcgaa ttttttgaag agatcaagca
    77221 aaagaaaaac ggtggaccat ataacggttc ttttttgaac cggctgccca atttaaaaag
    77281 tcaacggcac aaagtactat ttcgtcggtt agctttgatc atcactgtat tgggtatacc
    77341 gctgattttt ttgatctatt atgtttctcc ttatagcaaa ttacaagcag ttgcagtatc
    77401 aggcaataag acagtcaaca gccaagaaat catctctgat acaaaattgt cattaggaga
    77461 aaatgtttgg ggacagtatt ttcatcgatc tacttatatc gatcgcctta aaaaagcaca
    77521 gccaagaatc gaaacagcaa atatacattt caaagggatg aatgaattcg atttggatgt
    77581 aacagaatat aaagagattg ctttgatcgc aaaaaacaat caatactacc cagtgattga
    77641 aaatggaaca gtattagatg aaaaagtagc aaatcctaca aaaaatctcc ctatcttgga
    77701 agagttcaaa gactctgcaa aaatcaaaga attaacaaag caatacaatc agttatcatc
    77761 agaattacaa aaagcaattt ctgaaatcaa gtacacgcca agagcaagca ataaaaatct
    77821 gatccaattg aatatgaatg acggcaatca agttattgta aatatcaata atcttgcgaa
    77881 ccaaatgaaa tattattcgc aagtagccaa agatatggat gaaaaaggtg tgatcgacat
    77941 ggaagttggt atcttctcgc atccttacgg tagcactcaa gaaacggaag aatcgggcca
    78001 atcggaagaa acaactgaaa gtgaagaaaa tgcggatcaa acaaacgaat caagtgaaga
    78061 ggcagaaacg caaaaagcac aaacacctgg atcgtctagc acaaacggat catctgattc
    78121 aaatgattca agtgaaacaa gtcaaataga agataatcca agtacaactc cgtcaagttt
    78181 aaatgaaaat tgataaaaca actttaaaaa gtaagaatgt actttctaaa aaccagtaat
    78241 ttatggtaga attggaagca gtgaatatat ctattaataa gtatatttta aaacggacgc
    78301 tagttgttcg cttgtatatg gaatagtaag taggagggaa tcccattcat ggcaaaaaca
    78361 ggaatgtatg taggccttga tattggaacg acatctgtta aagttgtcgt ggctgaatat
    78421 atcgacagcc aaatgaatat tattggagta ggaaacgcaa aatcagaagg gattaaccga
    78481 ggcattatcg ttgatatcga taaaacggtc caagcgatac aacgagcagt acgacaagca
    78541 gaagaaaaag caggtatcca gatcaaaggc gtaagtgtcg gtttgccagc aaacatgctt
    78601 gaagtagaaa attgccaggg aatgattgca gttaacggag attcaaagga aatcaccgat
    78661 gaagatgtca gaaatgtggc ttcagctgcc cttgttcgtt caatacctcc tgaacgtcaa
    78721 atcgtgtcaa tattgccaca agattttact gtcgatgggt tcgagggaat caaagatcct
    78781 cgtggaatga tcggcgtaag attagaaatg tacggtctgt tgtttacagg acctaaaacg
    78841 atcatccata acatacgtaa atgcgtggaa aatgccggat taatcgtcaa cgaaatggtg
    78901 attactcctt tagcgctgac tgaatcaatt ctttctgacg gagaaaaaga ttttggtacg
    78961 atcgtcattg atatgggtgg cggccaaaca acaacggctg ttatgcatga taagcaattg
    79021 aagtttacca atcttgacca agaaggtggc gaatttgtca ctaaagatat ctctattgta
    79081 ttaaatacgt catttaacaa tgcagaagcg ttgaaaataa actacgggga tgcataccca
    79141 gaacggacat caccagatga agaatttcca gtagatgtga ttggtcagtc agaaccagtg
    79201 aaagtcgatg aacgctactt gtcagaaatt atttcagctc gaatggaaca gattttcaac
    79261 aaagcaaaag atgcattgga ccaaatcgaa gcattagagt tgccaggtgg cgtcgtattg
    79321 acaggcggag ctgctagtct tcctggtgtt gtggacttgg cacaagaaat cttcggcgta
    79381 aatgtaaaat tgtatgttcc aaatcacatg gggctgagaa acccggtatt tacaaatgta
    79441 ataagtatcg tggattattc agcaaacttg agtgaagtgt atcaattggc aaaaattgct
    79501 gttacgggtg aaacctcagc agctcgtcaa atggtagttg aacaagaaac aacaaacaca
    79561 tatgagagct atgaagcacc tgaagaaaca atctacgatg agccggaacc aaaagagtcc
    79621 ggagaaaatg taaaaaataa aatcaagggt ttctttacaa atatttttga ttaattcatc
    79681 ctgggaggaa taagatatgg aattctcaat tgataataat atcaatgacg gcgcagtaat
    79741 caaagtcatc ggagtcggtg gtggcggtgg aaatgctgta aaccgaatga ttgaagaaaa
    79801 cgttaaaggt gttgaattca ttacagccaa cacagacgtg caagcattaa aaaattcaaa
    79861 agctgaaaca gttatccaat taggccccaa atatactcgt ggtttaggtg ctggttctca
    79921 gccagaagtt ggacaaaaag cggcagaaga aagtgaacaa tccttacgcg aagctttaga
    79981 cggtgcagat atgattttca tcactgcagg aatgggtgga ggaaccggta caggtgctgc
    80041 accaatcgtt gcaggtatcg cgaaagaatt gggcgcattg actgttggtg tcgtgacacg
    80101 tccattcact tttgaaggac cgaaacgtgg ccgttttgct gcagaaggta tcgctcgttt
    80161 gaaagaaaat gtggatacat tattaattat ctcaaataac cgtttattag aagttgtaga
    80221 taaaaagaca ccgatgcttg aagctttccg tgaagcagat aatgttttac gacaaggtgt
    80281 acaaggtatc tctgatttga tcacagcgcc aggttacgtt aaccttgact ttgctgacgt
    80341 gaaaacagtg atggaaaacc aaggtacagc attgatgggg atcggtgtgg ctagtggaga
    80401 agatcgcgta gtagaagcaa cgaaaaaagc aatctcctct ccattgcttg aaacatctat
    80461 tgatggagct gaacaagtac ttcttaacat cacaggcggt ttggatatga cattgttcga
    80521 agcacaagat gcttcagata tcgtagcaaa tgcagcaact ggcgatgtaa atatcattct
    80581 aggtacatct atcaatgaag aaatgggcga tgaaatccgt gtgacggtca tcgcaacagg
    80641 tatcgatgaa tcaaaaaagg aacgcaagtc tagccgacca gctagacaag cacaaatgca
    80701 atcacctgct caaaagactg tattagatat ggatcaagct aaaccaactt cttcagaaga
    80761 agaaaacagt tttggcgatt gggatatcag acgtgaacaa aatgttcgtc ctagagttga
    80821 tgattccaat tttgacaata tcgaaaaaaa agaatttgat acattcaacc gcgaagaaac
    80881 aaaatctcat ggcgatgatg aattaaatac gccaccgttt ttccgtcgta aaaaataaag
    80941 gagaggaaga gcacatgatt gctgacaact tgcagaaaat caagcaagaa attcaggatt
    81001 cgtgtgctct tgttcatcgt gatccgaaag aagttacatt agtagctgta acaaaatctg
    81061 ttgaatccgc tcaagctgaa gaattggtta gagctggcgt tatgaattgt gcagaaaacc
    81121 gagtagataa attattagaa aagaaacaag atttatttga ttttcctgaa ataaagtggc
    81181 atttaattgg taatttacag cgcagaaagg taaaattgat tgtaaatgaa attgattact
    81241 ttcatgcgtt ggacagttta agattagcag aagaaatcca gaagcggtta gagaaagaat
    81301 tatcctgttt tattgaagta aatgtttctg gtgaggaatc aaaacatgga atttcaccag
    81361 atgagctttt accgtttgtg gaatctttag ctgcctgcac aaaaatcaag gttgttgggt
    81421 tgatgactat ggcgcctaaa gaagcttctg atgagcaaat ccataaagtg tttggtacgc
    81481 tgaaagaatt gcgtgatctt gttcaagcaa aaggttatgc ccatgcacca tgtagtgaat
    81541 taagtatggg gatgagtcaa gactttcaaa ttgcgattga agaaggtgca acatttatcc
    81601 gtgtaggaac agcgctattc aaagacgaat aaaggaggaa caaaaatgcc gcttttaaac
    81661 agaggagcaa ttgctaattt tttcggatta gctgatgagg aagagtacga ataccaagat
    81721 tatcctgaaa caacaaaaaa ggctgtacag ccaactaaaa aaaatacaac acagaatcaa
    81781 tcaactcatt ctgtatctgc tgcgaatact catgaaaaac aaaaaacggc gacttcacgt
    81841 cctgtaacgc atgaaagtat tcagccggct gaaaagaaaa aagtaattga actacatcaa
    81901 tcacctacaa aaactgtagc gaaagaaaga acagcttcaa gaacctctac acaacctaaa
    81961 gcaaatcttg ctggaaaaat cactgtaatg gaaccaagag cttattctga agctatggcg
    82021 attgctaaac gaatcattgc tggagaagca accttagtga attttcattt agtagaagaa
    82081 aaacaagcga gaagaatcgt tgattttcta acaggaacag tttatgcact agatggagat
    82141 atcaaacgtg ttggagatga gatttttctt tgtacaccga ctgggatgga gattgacagt
    82201 tcaaccgctc aatcttttgc agatgcgaat ttgtttgatc tgtaagagga ggaactacga
    82261 tttatactat tgcactatta cttcatttac ttcaacgggc agcctatttc tatagcatta
    82321 tcttgatggt atatgcattg ctctcttggt ttccaggcgg gtatcaatca gggctaggac
    82381 gattattagc taagatctgc gaaccgtata tcagtttgtt cgatcgtctg cctttgagga
    82441 ttggaccctt ggatttcaca attttagggg caatcctgat cttgaactta gccgtacaag
    82501 gtttagcaca gatcgttata tggataactg tccatttagt ttattgattg aagcaacaaa
    82561 atctttattc tcagaataga taggagggga aaattttgga tgcaaatgta taccagcact
    82621 ttcgggcaga tgaacgtaca tttatcgatt cggtaggcga ttggattgaa caggttcaag
    82681 gacaatatgc accctatctg accgaatttc ttgacccaag acaatcctat attttagaaa
    82741 cactgattcg acaaagcagt gatttgcgtt tcatgtttta tggcggatat gaacaggcag
    82801 aaagaaaaag atgtttgatt ttccccgatt attacgaacc tgtagaggaa gattttgaaa
    82861 cagcattgta tgaaatccat tatcctagca aatttgccag cctaagtcat gggaaaatcc
    82921 ttggaacttt agtgggaacg gggatcaaac gctcttactt tggcgatatc atctcggacg
    82981 gtgatcgctg gcaagtattt attgcaaatg aggtggatca ttttgttgct gcacaagtaa
    83041 caaagattgg aaaggttgct gtacgcttgg aaccaatcaa atacacagaa atgattatgc
    83101 cgaaagatag ctggacacaa gaaagaggaa cagttagttc catgcgacta gacagtgtga
    83161 tctctgagat ttataatatt tccagacagc ggtccaagca gctgatcgaa gctggtaaag
    83221 taaaagtgaa ctggacagaa aatacaagac ctgattttgt acttgaacta ttagatatta
    83281 tttcagtcag aggttatggc agagtccaga tccaagaact tgaggggaag acgaaaaaag
    83341 aaaagtacag ggtactgttc ggtgtattac gtaaataaaa taaaaaggtg gtttactcat
    83401 ggctttaact ccattagata tccaaaataa gacattcccg acaaaaatgc ggggatataa
    83461 tcaagacgaa gtagatgatt tcttagattt agttgttcgt gactatgagg aattgactca
    83521 aagaaatcga gaattagaaa aagcagtcaa acattctgaa gaaaaacttg agtacttcaa
    83581 tgaattaaaa gatgctttga accaatcaat catcgtagct caagatacgg ctgataaagt
    83641 aaaaacaagt gcaagcaagg aatccgaagt gatcgttact tctgcacaaa acaaagcaga
    83701 tgagttagtt gcgaacgctg aaaaacgtgc acatcaatta acaactgatg cagaagaaaa
    83761 agcaagaaaa atcttgacag atgcaacaga aaaagcaaga cagcttgcga cagaaactga
    83821 agatcttaag aaaaaaacac gagtattcca tcaacgtatc agcttgatgc ttgagtctca
    83881 attagaacaa gtgaaaagtc cggaatggga tgaaatttta caaccattct ccagctacgt
    83941 gactgacagc catgaagtga tcaaagaagt tttagcaaaa cagcttgaca atgaaaatga
    84001 tactgatgta aactcagaca caggagtcat agaagcacct atgacggcat ttgatacaca
    84061 ggctattgat atctcgatcg tgcctggtga aaatgaaaac gagtagaaca gaaaagcact
    84121 ttgttattct taaagcgagc cgatgagagt ggaagttcgg taagacactg catggtgaaa
    84181 gatcctctac ttgagacctg cttttccgaa attagagtaa gaagcagcgg ctgacctcgt
    84241 tattggtcac agagagtttg cactagatag atgcaactaa atttgggtgg taccacggca
    84301 tgttcgtccc ttgcggctga acatgctttt ttgtgtccgg aaaacaaata aaggagtgta
    84361 tggttgaatg aaaatgaaag aaaccttgca attaggaaaa acaaaattcc ctatgcgtgg
    84421 taatttgcca aaccgagaag gcgagtggca aaaagaatgg gaagaaaatc gaatctacca
    84481 aaaaagacaa gagttgaacg aaggaaaacc tagctttgtt cttcatgatg gacctccata
    84541 tgccaatggt aatatccatt taggacattc attgaataaa atcagtaaag acattatcat
    84601 tcgttcaaaa tcaatgtctg gctatcgtgc accatatgtt ccaggatggg atacacatgg
    84661 attgccgatt gaacaagtat tggctaataa aggcgtgaaa cgtaaagaaa tgtccatggc
    84721 agaatacttg gaaaaatgtc gtgaatatgc actttcccaa gtagataagc aacgagcaga
    84781 tttcaaacgc ctaggagttg caggagattg ggaacatcct tatgttacat tagatccttc
    84841 ttatgaagct gcacaagtac gcgtatttgg taaaatggct gaaaaaggct atatttacaa
    84901 aggattgaaa ccaatttact ggtctccgtc aagtgagtct tctttagcgg aagctgaaat
    84961 tgaatataaa gatgtaaaat ctccatctat ttttgtagct ttcaatgtca aagacggcaa
    85021 agatattctt gatgaagata cagcttttgt catttggacg acaacaccat ggacattgcc
    85081 agcaaaccaa ggtattgctg taaatccaaa atttacgtat gtattggtgg aagccgatgg
    85141 ccgtaagttt gtcgtagcga aagatttgct agaaacagtc caatcagaaa tcggttggga
    85201 aaatgtaaca gttctaaaag aatttgctgg acaagaaatg gaatatatga ctgcaagtca
    85261 tccattctat gaacgtgaat cacttgtgat tttaggcgat catgttactt tagacgctgg
    85321 tactggatta gtccatactg ctccaggaca tggggaagat gactatatcg ctggtagcaa
    85381 atataaacta tctgtagtgt cacctgtaga ctcaaaagga ttgtttacag aagaagcacc
    85441 tggatttgaa ggtatctttt atgacaaagc aaatcctatg atcactgatc tattaaaaga
    85501 aaaaggagct ttgctgaagc tagatttctt tactcatagt tatcctcacg attggcggac
    85561 gaaaaagcct gtgatctatc gggcaactcc acaatggttt gcatctatcg ataaattccg
    85621 tcagaatatt ttggatgaag tagaaaaagt agagtgggtt atcccatggg gtaaaacacg
    85681 tttgtataat atgatccgtg accgcggcga ttgggtaatt tcccgtcagc gtgcatgggg
    85741 agtaccactt ccgattttct atgctgaaaa tggagaagca atcatcacac cagaaacaat
    85801 cgaacatgtg gcaaaattat ttgctgaaca tggatcaatt atctggtttg aaaaagaagc
    85861 gaaagaactt cttcctgaag gatttaccca cccaggttct cctaatggcg aatttacaaa
    85921 agaaaaagat atcatggatg tctggtttga ttctggttct tctcatgaag ctgttttacg
    85981 tcagcgacca gaattatcat tcccagcaga tatgtattta gaaggatcag accaatatcg
    86041 tggctggttc aactcaagta tcacgactag tgtggctatc aatggtgtag caccatacaa
    86101 atcagttatt tctcaaggat ttgctttaga tggtgaaggc cgtaagatga gtaaatcttt
    86161 aggaaacatc attgcaccag aaaaagtgat caaacaattt ggtgcagata tccttcgctt
    86221 atgggtatct agtgtagatt atgaagcaga tgttcgtgtt tctatggata tcttaagtca
    86281 agtggcagaa gtatatcgta aaatcagaaa tacgatgcgt ttcttattag cgaatacaga
    86341 agatttcgat cctaaaaaag atactgtttc gtacaatgat ttacgttctg tagacaaata
    86401 tatgaccgtt cgattgaacc aagtaatcaa agaaatccga gaagaagggt acgacaaata
    86461 taacttcatg catatttacc gtacagttat gaacttcttg acggttgatc tatcgtcatt
    86521 ctacctggat tttgctaaag atgtagttta tattgaagca gaagatgatt atcaacgtcg
    86581 ttgcatgcaa actgttttct atcaaacagc tgtagctttg acaaaattat tgactcctat
    86641 cattccgcat acagcagaag aaatctggtc attcctgaaa gaagaagagg agtacgttca
    86701 gttaagcgag tttcctggtt atgaagagtt tgcaaaccaa gaagaattga tggatacctg
    86761 gactgctttc atggacttcc gtgataatgt cttaaaagca ttggaagaag caagaaacag
    86821 caaattgatt ggtaaatctt tggaagcaaa actaactgtt tatccaaaac aacaagttcg
    86881 tgaaatgtta aaagctttgg atgcagatat tgcacaatta ttgatcgttt caccagacta
    86941 ctttgaagtt atggcagcag atgaacaagt gccagataac gctatggtat ttgatgatgt
    87001 tgctattaca gtggaaaaag cagacgggga aacttgcgat cgctgtcgcc aagttcgtaa
    87061 agatgtagga gtagatgaaa aacttcctca tctatgcggt cgttgtgcaa aaatcgttga
    87121 agacttctat cctgaagctg tagctgaagg attcgaagaa aagtaaaagg gaaaaggggg
    87181 tgtgacatgt tctttgtcac accccctttt gttatcaatc gtttaatttt ccacgttcac
    87241 gataccagtt atctggttgc cagatccatt cgaatccgtc tttttcaagt agttcgaaag
    87301 ctgctttagg tcccattgat ccagctttgt agttgggaaa atccggttgt gtttggtccc
    87361 aagcttttcg aatgacatcc acgatatgcc aagattgagc gacttcttcc caatgagaga
    87421 agttcgttcc atcaccattc aacgcatcta atagtaattt ttcgtaagct tctgggctat
    87481 tttcaaccat ttctgcacta tttctaaatt ccaatttgat tggttccgtt tcaaatcctt
    87541 gccctacttc tttcccattc aaggataaag aaaatccttc agttggctga atatagatcg
    87601 ttagaacatt aggtggaagt gtcgtatcgt cacatggttc atcgacagat gttttgaata
    87661 cattaacagg aacttgtttg aatacgatgt tgatccgagt ccctttttca gtcaaacgtt
    87721 tgcctgtacg tacatagaaa ggaacacctg accaacggaa gttatcgata gtgaatttgc
    87781 ctgcgacgaa tgtttcagtc tctgattgag catccacttt gtcttcttcg cgatagccct
    87841 tgaattgtac accatccaat tcaccttgag catattgccc gcgaacgaag ttttctaaca
    87901 cttcttcttc gttataaatg cggatagctt tcaatgcttt gatcttttct gtacggattt
    87961 ctttttcgga aaatgctact ggcggttcca ttgcaagtaa tgctacaacc tgtaaaatat
    88021 gattttgcac catgtcttta agtgcgccac tatgatcgta gtagcccccg cgatcttcta
    88081 caccgaggtt ttcgccaaaa gtaatttgga tattgtcgat atagcgattg ttccattgag
    88141 cctcaaaaat attattggca aaacggatag ctgagatgtt ttggatcatt tcttttccta
    88201 aataatgatc aatcctgaaa atatcttgtt ctgggaatac ttctctgatt tgctggttca
    88261 attcaaaagc agactggtaa tcagaaccga acggtttttc tatgatcaaa cgattgaagc
    88321 cattttttgt cataatattt tgtgatttca aatgagaaac gatcgttcca aaaaattgag
    88381 gtgccatagc caaataatag acacggttac cgtttaattg atagtgtcca tctaatcggt
    88441 cagacaattc ttttaatgtc tgataatgcg ttgaatcatt tacatcatgg gattgatagt
    88501 aaaaatggct tgcaaaggta gttgcttctt catctgaagg attcaatgca cggattgttt
    88561 ctttgacaac ttcacggtag tgctcatcgc tccagggacg gcgagcggtt ccgattacag
    88621 caaaatgctc gcctaaattt ccttttctgt aaaggcggaa caaagacggg tacaatttac
    88681 gctgggctag gtcacctgta ccgccgaata tcgtaaacaa tacatttttt tcattagaca
    88741 tgtggataca ctcctttata ttttatcgac aaaaatcgtg ctggccgcct taaagctgac
    88801 ggggattttc tttctatcat tttggatagt gatcggtcct tcataagctg cgatgtcaac
    88861 gatctcatat tcttcgttga tattcaggtc aatagtgact aagtaatcca acaattcttt
    88921 ttcatcaagc actcgtgcga tacgcacttt tgtaccgaca ggataggact ccaatgtttg
    88981 tcggcgttct tcatggacaa cttcctcttt tttaggaatc gatcctccat gaggacaatg
    89041 ttcaggatga ttcaaatagt tttctaaatg atctgcaaga tgttccgaag tcacatgttc
    89101 caatacttca gcatcatcat ggacttcatt ccagctatag tctaaatgtt caactaaaaa
    89161 aacttcccat aagcgatgtt tgcgaatcag actgctagct ttttgcagtc cgcttgcagt
    89221 caattgtaca ccttgataag gggaatgttc tacaagctct tctttcacaa gtttagaaat
    89281 catttcactg acagatgcag ctgagacatc tagactagat acgatttgtt tattgttgac
    89341 tttcgttgta tctccaccta gttctaaaat gattttcaaa taatcttctc gatttggtgt
    89401 catattcgat catcctttca tggtaaaaaa ccatcattag taagtgtaac aaaaaaaacg
    89461 ttaattgact atttttctaa ataaaaaaca aaggattttt agacgttttt acaacaaaaa
    89521 acgaaagatg atagagaaga ctcattcttt cgtttataaa ggatatatat atacattggg
    89581 agggatctat ttttcagata acaacttata tgaagtgtct gcagattcgt cataaagagt
    89641 ttgttcggga taagaaaaga taagataaaa accatactga tcacgtacga ctaaacgata
    89701 ttcatctatt tctaccacag atgtgccaag agactgaccg ttgatcaaaa acgtgtaatc
    89761 agatgtaatc tgtaattgtt gtttttgctg gctatcacta aagaaccatg taccttgata
    89821 ctttgagagt ccttctgact tttccgcttg ttttttcttt ttcaagtaaa taaaacttga
    89881 gagaacggta atgagtgaac caagaaaata gatcattttt tttatcacca aatcactcct
    89941 ttatgagaaa ataatcgcat agacatattc tttcttcttt atttcattgt accgaataaa
    90001 agctaaaatt tctctaagac tttcgactgg tttttttact gtttttctac aaattatgat
    90061 aggatacata gtaggaagaa aggtgacata atttgaagta tcagcaagtg gaaatagctt
    90121 tttttattga ccgcccgaat cggtttatag cacattgtat gaaaaaagac ggagaaataa
    90181 ttattgcgca tgtcaaaaat acaggtagag gaaaagaggt cctgatacca ggcgctgaag
    90241 tggctattgt atttgctcct ggacctaaac ggaaaaccgc ctatgatctg attgctgtaa
    90301 aaaagaaggg tgactggttt aatatcgata gtcaattgcc taatcggctg gcaattgatg
    90361 gtattttaga cggcacgatc cttttaccag gattaactgg tccatttacg gtatacaagc
    90421 gtgaagtaac ttatcttcac tccaaatttg atatttattt agagacggtg gtcggacaaa
    90481 aagcatttgt tgaagtcaaa ggtatgacac ttgaaaataa agcgattggt gcttttcctg
    90541 atgcgcccac actcagagga ttgaaacata taggagaatt aacgtatgcc gcacaagatg
    90601 gttatgccgc ttatgtcttg tttattgctc agttcgaaca tcttcatctg gcaacgatcc
    90661 atgaagaaat gcaaccagca ctagctgata tggttcgaca tgcgcagcaa agcggagttc
    90721 aaatcctcgc ctataattgt caagtatcgg cagatgaggt aactgtcaag caggccattc
    90781 catttgatgt agatatccct tttgaagatc ctatacaata gaaagaaggt aaaataatga
    90841 tcaacttagg tattatcgga acaaattgga ttactcatca atttgtccaa gcagctttaa
    90901 gcacaaaaaa atatgaattg acagcggtat attctagaca tttggaaaaa gcacaggaat
    90961 ttggttctca ttatgaaggg gatatcgaat tcgcaacaga tttgaagact tttttcaata
    91021 ttactcatat ggacaccatt tatattgctt ctccgaatag tcttcacttt agtcaagcta
    91081 agcaagcaat tttggcagga aaaaatgtga tagttgaaaa gccagctttt tcgacgccaa
    91141 aagaaatgga tgaaatcatc catttggcaa atgaacacaa tgtgtatttt tttgaagcag
    91201 caagaaatat ccatgaatca ggttttaaaa agattgccga ttacttacca ttaaaagacg
    91261 agataatcgg tgcaaatttc agctatatga aatattcttc gcgctatgac caagtattag
    91321 atggagaaga accgaatatc ttctcgactc atttctcagg tggtgcattg atggatttag
    91381 gtgtttacct tgtatatgca gctgttgctt ggtttggaat gccaaaagaa gtccattatt
    91441 tcccaagaaa gatttctact ggtgtagatg gtcttggatg ggggatctta cgttatgaga
    91501 attttgatgt atcgatccag ccaggtaaaa tcggtgattc ttatttaccg tcagagattt
    91561 attttgactc aggaacgcta gtgatgaatg gagtcaatgc aattgaacaa gcacaatttc
    91621 atgatcgcgc gcataaagaa atcattgatt tggcggtaac agctgcagaa aatccaatgg
    91681 cagatgaagc agaggatttt gccaatgtca tggctcatcc gaaagatcca gcttggggat
    91741 tgttgtatga agagtggatc gagctagcta gaaatgtgaa ccaagtgatt tatgatttaa
    91801 gaaaaaatgg cggcatcaaa ttcgatgcag ataatgagga agatttttaa tgaacgaatt
    91861 tgtacaagta tttcccgaaa attggcagaa aaaatatgag gataaagggt ttatctcacc
    91921 ttctcttatt caacgagcag tttttcagcc actaagtaat aaacaaagta tagtagcggt
    91981 ttctcctaca ggttcaggta aaacactggc ttatctttgg cctctactac taaacgtgga
    92041 accaggtgaa gcaagtgcgt tggtcatttt tgcttcttct caagaactag ctattcaagt
    92101 agcagatgtt gcacgtgaat ggggaaaaga caaagagttg aaagtccaat ctttggtggg
    92161 cggagccaac gtcaaacgtc agattgaggg tttgaaggaa aaaccagaaa tcttgattgg
    92221 tacaccagga agaatattgg aattgatgaa agcaaaaaaa ataaaagcac atcaagtgaa
    92281 aacaatggta tttgatgaag cagaccagct atttgacgct gggaacagcc aaatcattga
    92341 tcaaattctt catcaagctc caacagagta tcagctagct tttttttcag cgacagcaga
    92401 tcgttccctt gaaagcattg aaaaaatcac tgggaaaacg tttgagacaa ttgacgtgac
    92461 agcagaggac gattctcgaa aaggactgag acattacttt ttacgtgtac cgatacgaaa
    92521 gaaagatgac tacttgagac gtctcacgca tatagaagat tttcatggtc tgattttctt
    92581 taatcaactg actgaattag gcgtaatgga agaaaaattg ctgtatagag gtgtaccggt
    92641 aggaagtctg gcctctgatc agaacaagct actccgaaaa gcagcgctag aacaattcaa
    92701 aaagaaaatg gtcagagcac ttttgaccac agatgtggcg gctagaggtt tagatattac
    92761 aggtcttcct tatgtagtga atgcagaagt tccgttaagt gaagaagctt atttgcatcg
    92821 ttcgggaaga actggtcgaa tgggtaatga aggaatagta attacactcg tacaagataa
    92881 taatctaaga gatttaaaac ggcttttacg tccatcaaat ataacacttg aagagatttt
    92941 tttatacgga ggtaagctgc aaactgagca gccaaccaaa gaagatgcag ctcctgcagt
    93001 aaataaaaag tatgcgaaaa ctttttctgg aaaggagcag aacccagaat ataacaaaga
    93061 aaaaataaga aaaaaagtta aaaataaatc aaaaaaagag agaaataaag gagcaaggcg
    93121 caaataagcg cctttttatg ctatgattat gaaaacggga acaaaattgg ttgccagagg
    93181 aggggttatg tgaaagaacg tcaagaagag atcttgcagc tattgacaga aaaccaacaa
    93241 ggattgacag caagtgatgt agctgagcgc ttaactatcg atcgaagcaa tgcaagccga
    93301 tatttaagtg aactatacaa ggcccatcat attgtaaaaa ccgctggccg accagtcgtt
    93361 tactctttgc caacggaaaa gtcaaaatct gatgaagtgc atgtcgactc ttctacgcaa
    93421 gtgacttttg aaacactcgt tggagaaaat gattctttaa aagtcagcat acagcaggca
    93481 aaagctgcga ttctttatcc accgcggggg ttgcatacga ttatttttgg agaaactggt
    93541 acagggaagt cgatgtttgc tgaatgtatg tatcattttg caatcgattc agagatgctt
    93601 tctgcagatg cgccatttgt ttctttcaat tgtgcggatt atgctcaaaa tccgcaactg
    93661 ctctttggac acatctttgg gatcaaaaaa ggggcttaca caggagcagc tcaagatagt
    93721 cccggtctaa tagccaaagc agacggcggt atattgtttt tagatgagat ccaccgttta
    93781 ccgccggaag ggcaggaaat gctgtttact ttcattgata aaggtattta ccgtccgctt
    93841 ggagaaagtg cacaagtaca tgaagcatct gttcagatca ttggggcgac gactgaatct
    93901 tcagaaagtt tcttatctac gttcaatcga cggattccta tggcaatcac cttgccgaat
    93961 cttgcttcac gttcactgga tgagcgttat gaaatcatct ctctttttat caaacaagaa
    94021 gcgaatcgtt tgaatcaacg tatcgatatc gaaaaagaag cgattcttgc cttcatgctt
    94081 tatgatgcgg aaggaaatat cggtcaagtg aaacgagact tgaaactagt ctgtgcaaaa
    94141 tcttttttac attaccgtac tcatcatgag aaaaagctaa tcattcgaaa agaagaactt
    94201 tcccttcaag tacaaaaagg attactgaaa atcaaggaaa taccggaacg tctcgaccga
    94261 ttcatggaca gcaaaagtca gtatttgaca tttgaaccag gatttgctga tgttgtctgg
    94321 tcacaagatc cagaacgaaa catgcaggtc tataacgata ttgaggaaaa agtcacttct
    94381 ctttccgaaa ccggtgtgga gaacattgat ctagagaccc tcatttcaaa agatgtggat
    94441 gcttatttcc agacatatgt caaagaattg actaaaagtt cgattcccaa agatcttttg
    94501 ccagatgaaa tctggcggtt aaccaatcaa ttgtatgatg tggctgaaaa acggttagac
    94561 cgtatttata atgaaaaagc tcgttttgct tttgctttgc atctgcaaag tacattggat
    94621 cgtgtgagag aaggtcatat gatcgtccac ccagatttga ataacgtacg gaaaaatttt
    94681 aagagggaat tccaggtagc aatcgatctt tcaacgatca ttgaagaaga agaacaagtt
    94741 gagattcctt ttgatgaaat cggctttatt agtatgtttc tttctatcaa tctaggagaa
    94801 agtgagcctg ttaaagaaaa caaagtagat gttctcatat tgatgcacgg cagacagact
    94861 gcttcaagca tgttggagat ggcacaagaa ctattaggaa caaaagtagg gaaagctttt
    94921 aatatgccac tggttatgga agttcaaaca atgtatgaag aagtgttaca atatgtcaaa
    94981 aactatcaag agcatttgac gaatggccta ctcttgttaa cagatatggg atcattaaac
    95041 accttcagtg atttgattta tgaagagact ggcattcgga cgaaagctat cacgatgaca
    95101 agtaccatga ttgtgataga agcgatacgg atggcaagtg ttggaagaag cttagaagat
    95161 atttatcaaa atatccagct ttcctttgaa tcgatcgtac gtgatcagtt caaagcggaa
    95221 aagtctgaaa ctttacagcg taaaaaagcc gtaatcgtga catgctttac tggtgaagga
    95281 gtagctgcca aattatatca gcgtattatg ccagtgatta atcaaaataa ggtagaactg
    95341 atccagatgc agtttttaga acgtgaatca ttcaaaaaac acatcgatgc cttattggaa
    95401 gaatatgaga tcaaagcaat tgcgggaaca gttgatgttg attatcaaaa tatcccattt
    95461 ttttcagcct atgacgtttt tgatgatgaa aaactaaata ttttaaagcg tatagctgat
    95521 gatgagatcc cgacagctaa aattgtcgat tcacttgctg gatcattaag cgatgtcttt
    95581 tctattgatg aactgatccg ttcattgcaa aagacagttc agcagatcca gaccgatttg
    95641 tcgattatcg tggaacctgg agtagatact ggaatcgtta tccatttagc cttcatgtta
    95701 gacggattga tcaaacaaga aagccatcgg caatttgaga aactgtctat tttctcaaaa
    95761 atttatcgtt tggaaatgga tatcgttcgg gcaaacttga tggcactaga acgaaaatat
    95821 caggtaaaaa ttccagaaga tgatatcgca tttcttacac aaatgtttct tgaaaataaa
    95881 ataaaaaaat gaacacacta atcatactgt ttacacacta aacatctgtg tgcgcactat
    95941 aaaaaagagc taaaaagcat gaaaacgcta tttcagctct tttttttatt ggcatgcttc
    96001 ttgcgttata taaaagtgta aaaaaataaa aggagtgtta aaaatggcaa aaaaaacaat
    96061 catgttagtt tgttcagcag ggatgagtac gagtttattg gtcacaaaaa tgcaaaaagc
    96121 agcagaagaa aaagggatgg aagccgatat ttttgcggtc tctgcctcag atgcagataa
    96181 taatttagaa tctaagaatg tcgatgtatt attattaggt cctcaagtac gtttcatgaa
    96241 agctcaattt gaacaaaaac ttgcgcctaa aggtattcca ttagatgtca tcaatatgca
    96301 agactatggc atgatgaacg gagaaaaagt tcttgcacaa gcagaaaatc taatgaaata
    96361 aatcaagtat gcagttgggg gtataacaac gtggaagatc aacaaaatct agaagccatc
    96421 atggggttaa tcatgtttgg cggtaatgca aagagcgatg caatggaagc gattgcggct
    96481 gctaaaatcg gtgattttga gttagcggat aggaaaatcg ctgatgcaga agaatcactt
    96541 atacaagcgc atcatgcaca aacagacatg ttgacacaag aagcacaagg aaatcatatg
    96601 caagtgacat tattgactgt tcacagtcaa gatcacttaa tgacatctat tgcgtttact
    96661 gatttagcaa aagaaatcat cgaactttat cgtcgcgtat acagcgaata aatacaactt
    96721 cttttttgaa cggaagaaga aaaatttttg aacggatttt ttattttgtt ataaggagaa
    96781 ctctctttat ataaaaaact tataggagga agtaaaaaat gaacggacta tcaagttgga
    96841 tggagaaata catcctgccg gttgccgcaa aaatcggagc gcaaaaacat ttagttgctt
    96901 tgcgtgatgc ttttatcggc atactgcccg caacaatggc gggatcagtc gctgtaatga
    96961 tcaatgcaat tattcgtgat ttaccgcaac agtttaacag tacctatgct gacagtttag
    97021 cagcagacaa aggaatcttt gccgtattga atgtcatcat cggaatcaat ggttttgtct
    97081 ggaacggtac actagcaatc gccggattga tctttgcctt ttcttggggg tataatcttg
    97141 cccgagctta tggagtaaat gatctagctg gggggatcgt tggtttagct accttgattc
    97201 aaggtatttc ctttggtcca gcattatcag cagcattaga tgtgaatgtt ccttcaaatg
    97261 tcgcagatgc aatcaatagt tctgagattg gtgcaacgat tgcagatggc acactgtcag
    97321 ttggattatg gggttggcta aaactagatc atttgaatgg aaacgcttat tttacagtta
    97381 tgatcatggg agctatttca gtcattattt tttgtaaatt gatgcttgcc aacattacga
    97441 tcaaaatgcc tgattcagta ccaccagcag tatctaaagc atttgcagcc attttaccag
    97501 cgacgatcgc tttatacgtc attgctatta tcaattatat cgtaggtcgt gtagctgatg
    97561 ggcaactgat cattgatttg gtgcaaaaat atattgcaga accattccta ggattatctc
    97621 aagggttggg agcagtattg atcgtcacag tatttgttca agtattctgg ttctttggta
    97681 ttcatggatc aaatgtattg gcaccagtgc tagagggaat ctggggacaa gcacaactaa
    97741 tcaatattga tattttccaa aaaggttata acggaaaaac tggtacacca gccgtgttag
    97801 atgcaatcga agatggaaaa gcttatatgt gggtccgcgg atcgttcgat gcttttgcat
    97861 ggtttggcgg atcaggcgga acgatcgtct tactgatagc tatcttgatt ttctctaaac
    97921 gtgcagatta tctaacagta gctaaattat ccattgggcc tggtatcttc aatatcaacg
    97981 aaccagtgat gtttggtctg ccaatcgtat tgaatgcaat catgtttatc ccattcttga
    98041 ttgctccagt agtagcaaca gcaattggat ggacagctac ttatcttggc ctagtcgctc
    98101 cggtatcgca gcaagtcaca tgggtagtac cgccgttctt attgtcattc ttagcaacag
    98161 gagcggattg gcgggcaccg atcgtaacat tagtatgtat ggtcgtgact ttcttgattt
    98221 gggcaccatt tgtcatctct gcaaacaaaa tggaccctgc cgcaggcgaa caacaataag
    98281 atgaacgtga ggagcgggac gctttaagtt tcgttcctca taatgaattt tcgaggagga
    98341 actgaaatga ttacaattgc cagtgcaatg caacaagatg aaatcaaaga attgttagaa
    98401 ggatacaatg aagaaggaat gacttttaca tttaaagaaa aacaaggaat caagctgttc
    98461 tttgaaacaa gtgcagaaga tccggaagtt gcggctaaaa aagcaaagga actaatcaaa
    98521 gcacagcctt ggggaacagt cctttatttt caatcaacag ctgtttagaa aatggtttaa
    98581 aaagatagga tggttgagat gataaaaaac ggtttatttt tatgtagtat tggttctttg
    98641 atcgtgttgt atagtttgaa tccacattcg caaaggtatg atttgtatag tatggtcaca
    98701 ggtctttttc taacaggatt aggaatctat ttcttcatga aggggaaaaa aagagaagaa
    98761 gcaaaggaga aaaataacta atggaaatca cgaaaaaatt aaatattcca gcatcgtttt
    98821 tttacgataa agttatggac tctgtccttt tcgatgtacg taaagcgacc ggcaaatcag
    98881 taactagaaa acagctgaaa aatttggagt acgtcaaaca attctcgcaa aataaccggg
    98941 ctcgcataaa aatcgaagaa gtcattgaaa accagtctta taagtttcgt acatcgacaa
    99001 cgaagaatga attcgtcgtt cattatcaaa tcaaaccatt ggacgattcg acctgtgagg
    99061 ttcattacac agaaaaaatg gagtcttatg gcatgcttca aaagttgaat gatatgcttt
    99121 taggaacaat cttgatgtat tttaaacgga gacgtttcaa aaaaatgcta gatatgatcg
    99181 aagcaacgta ttaaatcaat gaaacatggt actatttagt tattgaaaaa tgaagtaagc
    99241 tagaaggaat ttttcatagg aagatagatc tttcctgcga atcctcacta gcttttttgt
    99301 aggaaggggc agcaaaatga caaacaaagt aagagagcta ggtgtatctt cgattgagga
    99361 aatgtttgat ttagccactt atgcatttaa tggggcagat acacctgaaa ggcgagaacg
    99421 ttttcgtaca cttgcggaga attcttggaa ttacggattt tttgatgagg aggatcggct
    99481 aacaagtcaa gtcatggcga ccccttttcc agtgaatttt tacggacaag agtacctaat
    99541 ggccggcatt ggctatgttg cttcttatcc agaagcaagg ggacaaggcg ggatcaatca
    99601 gatcatggaa aagatccttg aagattgccg tgatcgtaaa gtaagcttat cttatctggc
    99661 gccattctcc tatcccttct atcggcgcta tggctatgaa caatcatttg ataaaatcag
    99721 ttatcaacta aacagtcgtg atgtgccgtt tatcaaaaaa aaatctggaa aaataaagcg
    99781 tatggatttt gaagatgcaa aagctgcaat cagaagaatt tatgaacaga tgccggaaaa
    99841 ccaacgagct ggtctgaagc gcgaagactg gtggtatacg tataaattca agcaaaaagg
    99901 caattaccag tttgctttgc attttgatga taatgaggaa gcaacgggat atatcgttta
    99961 tcagcttgca acgtcttcct ttattattgc ggagtgggga tttttggatc atgatgcttt
   100021 ttgcagcctt gttcgcttcg taagttctca caatggtgct tttgaaacat ttgaatattc
   100081 atgcggctac ggcggtaatg atcaaaatta tctattagaa aatccatttg cttctgtaat
   100141 gatcacacct tatatgatgg cgaggatcgt agatatttct ttgtttttgg aaaattatcc
   100201 atttaaaaag agacaagctg catttgccct acaaatagaa gaagatcatt atgcgaaatg
   100261 gaatgaagga atcgtggaag taacaatcga aaatggaaaa aatcatctct caaaagtaga
   100321 acaaacaaaa ctcccaatcg ttcgaggaag tatccaacat atcacgcagc tattattagg
   100381 gtatcgtaaa gtggaagagt tggtattcca agaaagaata caggtgacaa aagaatatga
   100441 agaaacgtta agctcaatct tgccacagca acagccaatt cttaatgact atttttgata
   100501 aaaaacgggt gatgacaata tttttgtcac cacccttttg tttttcattt ggcatttgaa
   100561 ggaaaatgtt aaagtaaatc ctcttttttc gtaaatttga attttttgtt ttcttttgtt
   100621 ttagggtttt cttttttgtg gtcttggatt gcttctttcg taatcttttc ccgatttttt
   100681 ttagatgaat ctaagcgttc tgcgtatact ttttcttttg gcttatcatt cattggaaag
   100741 gacctcccta cattatttca ttctacctct agtttatcat ctgttaagga ctagtggaaa
   100801 cgttttgcct aacttataag ctgatttttt tagcagataa gcttgcaagt aaaaaacaaa
   100861 caagctacaa ttgatttatt gaaattgttc ctgtagctca gtaggataga gcaatcgcct
   100921 cctaagcgat aggtcgctgg ttcaattcca gtcaggaacg tataaataac ccctgtatcc
   100981 tttgcggtac aggggtttgt tttgtatttg tgccaaaaat gtgccaaact agttatcatt
   101041 tttatataaa ctatcgaaca cagtattgat tttttcttta tcctgatctt caagctctcg
   101101 aacaatatga agataagtag acattgtagt ttctaaactg ctatgtccta aacgtttcga
   101161 tacgctaagt atatttactc cttgataaag taaaatagat gcatgtgtat gccttagtcc
   101221 atgcaaagta aattgctttt caatccctaa ttcttttaat tttttgcgca aatatttgct
   101281 gacggcgttt gatgaaacta atccattttt taagttgaaa aaaacaaaat tatgagggtt
   101341 tttgatttca aaattctcga ataattcttt ttgattgatt ttaaactttt ttaagagatc
   101401 aatcgtatgt ttatcaatgg aaattttcct atttgaagtt tcgttttttg tttttcccca
   101461 ttcatttaat ttataattcc atgttttatt aatagtgatg atttgatctt cgaaatcgat
   101521 atcttcccat gttaatccta gaagttcagc aaatcgcatt ccagtggcac cagcaactaa
   101581 cacgagcata ggagaagagt actgcgcaga aaggttttct tctacgagtt tcattaaaga
   101641 tttaaattga tcataatcta aatatttatc ttcttttggc ttcaatgaat cttttccttt
   101701 gattactgct tttctagttg gatcaaacgg aattaatcct tcttctacgg catctttcaa
   101761 cgacgctcta atatggttat taaacttaat aacggtagat tttacatggt ctttagcata
   101821 cttatttaaa aagcgttgat atcccactct atctaaatca gaaatcaata ccgctggcat
   101881 atatttcttt atgttcatta acgtatcttc gtattttcta taagtgatag gagatactgt
   101941 tccttcttta taaagttgca tccaatcctc aaagtaatct gataataata gatttttgcg
   102001 atccccttta aggcctttgt tcaagttata ttctaattcg ttggcggcat cttttgcttc
   102061 tccttttgtc ttaaatcctg attttcttat cttcgtgtat tttccgtcat cttttttgta
   102121 tgaaatttcg tattgccaac tatttccacg tttgactaat cttgccataa ttgaatcagc
   102181 tctctttctc tgatacaata ggaactataa agaagcccat tgtttgggtt ttattatttt
   102241 ttgcacatcc tttttgcttg ccggcgcaag gatgtgctat ttgtcgtttt aatggtataa
   102301 ttggatgtgt attagatcat ccaatcagag gtgtttatta tgattaaagt gatttttaaa
   102361 agaataactg aacttccaga gtttagatta tttgttgatt attggtatgt ctggtttttt
   102421 attgttgcat tgctgatagg tctagatgtc atattagaaa gaaaacttaa gtaagagttg
   102481 agttaataaa ttgaattcct aaatgagata ttttgtagcc catattttgt ttgccgacat
   102541 cacctaatac tatggagcta atcgtttttt ctaacagacc aaaatcagat aatctattta
   102601 agctaccatc tattagctct tgtgaatagc cagacatgct gatatttcca gtgaaatttt
   102661 cgtttccacg actcattaag catgctaaca attgaatctc aatcgatgtt aattgattca
   102721 gtacaagaag ataatactcc tcgttatccc atgaagcgtt gttaattcga agtaaacaat
   102781 tcttataaag atttttatac atatctattt tattttgtgc ctttgatttt tctacctcgt
   102841 catttatccc ttcgaatatt ccaatgagtt ggtccttgtt ctctaagttg aaaacatctt
   102901 ctggaatttg atcgcgaatg ttttctaatg attcgtttaa atttttgtag aatttctcga
   102961 tgcgtttgaa acgcttctcg tttttagacc caaaataaag tgactgcaca acgccaccaa
   103021 tataaggaat tgctccaata ccgccttcaa ctattaattc aagatattct tttttggtta
   103081 gtttttcatt gctattatcc atagttacct cctattttgt catttccttt acaagcattg
   103141 tgactcctga tggcactctt ttgtataggt tttattattg tgcacaatct aactcttagt
   103201 ggggcgtggt tcatttattt tttacttact ttactattaa tcatatccca ttgagcatag
   103261 gatttttcta tgttcgatcc tcttgaacta atttctcctg taaaagttac tttatcgccc
   103321 tttgtaaagg tatcagcatt gtttaagtcc ttcgcaaaaa ttacatatga aactttaggt
   103381 gttgcagaaa tatcattcca acttttatca tcgtactctt tgtctgctat aatggctatt
   103441 ctagtagtca ttgattcgat aacagttcct tcaaaagtat atgttttacc actaatatat
   103501 ttagtaaaag ctgtattttg ctcagtagct ggagtaatag aataataact atctaagaaa
   103561 gcaccccagt catgattatt tgtctctaaa aattcttcaa attgagttag gcttttattg
   103621 ctgctgttag atgtagtagt ttgagtatca gatgatgagc tttcctgttt gttattgtca
   103681 tttgcctcgt ttgatgagga aagcgagaaa cctacggtag taaaaataat cccgataata
   103741 aggagaatca taggtgtttt cttatttgtt tttttgataa atcttacaat taacatgatt
   103801 aaacctataa taaataaaac aataccagta aaaccaaata taccgtccat taatagatcc
   103861 tctttctctt ttgatattga atattataaa ccaagcaatt cttttttctt aaaatcgaat
   103921 tcttcttgat taataatccc ttcatctaac aactctttat actttttaat ttcatctgca
   103981 cttgaaattt gtgtttcttt ggaattatta tctaatatag attgttgctt ctctatatat
   104041 ttttttaaat tttccatttc attccaatat ttttttgtaa acataacggt gttttcatct
   104101 ttcgtggccg ctaatatacc tccgcgactt tcgtttccgc ctagcaaggt aaattgtata
   104161 taaccattac tcatacctgg tttttttaat tgtacggctg atatattttt aaaggggata
   104221 gttttttctc ctttaatacc ttgattaact aaatttataa atccttttct aataattgaa
   104281 atagaatcat cagttacttt aatcaaggtt tttcctggag attttattaa aatctctttt
   104341 tccatttttt cttcctcatt tctgtgatat gatttttttt gtagaagctc atatatgagg
   104401 aaagagcccg tgttgcagca cgggcttttt taatgttttg ctgaaatcgg tttttttaat
   104461 aattcttgat gtattcatac atattgcctt gcgtaagaat attttttctt aaaatagcat
   104521 tggcagacag cataacaagt gtatctgagc ttattctgaa tagaataata ctccataaat
   104581 ttttcgagat taaactgaga ttcatcagtc agttcgttct caatatagat atttaataaa
   104641 attagaatag ctattttatc tgcttctgtt tcaaattttg agtgaaaagt tgtagaagta
   104701 tcgtacaaaa ctgaaaattc aaaatgagag gcgctgaaat gtgcaagttc atgagataaa
   104761 tgaaaggctt ctgcagtttc accgtataga ttttcattca aaaaaatgat tctgggtttt
   104821 ggatagtaga aaccaggctc tttcatctcc atataaacta ctttcaaatt gtattcgctc
   104881 aacatttctt tcaatttcaa atacatacaa accatcactc caactattca ttttcctcta
   104941 aagctttagc aattgcaatc gctttacgca ttgtctcctt agatatttct tttccatcaa
   105001 aagaaaaaac agtatcgtct tctgataaat ccacatgttt aggggtttct ctttcttctc
   105061 tacctagaag gtagtctaca gagacatcga aatagtcagc aatccgactt aattcatctg
   105121 aattaggagt attatttttc cactttgcta gataaccgtt agaatatcca aaattaattt
   105181 ctaactgccg tatagatatc tttttcctct tcgccaagtc ttttattatt tcataggtat
   105241 tcatcgataa aacaaccttt ctaaatgttt acaaaaaaag tttagaaaaa tacgcagaaa
   105301 taatttgact aattctgagt aatgagctat actatatctt gtaaacagat ttaacaacta
   105361 aaaagacaac aaaaaacact attgatatgt aaatgcagac cgccaagaaa gctttaaaat
   105421 caatgttttt atgtcttatt taattatgct cttagtatag agtattactc agatactgtc
   105481 aattgaattt agaaaaaagt tgttaaattt gtttacgaat ataaaagaaa ggaatgagaa
   105541 atatgaacac accgcaaatt tttaatttcg aacaaaacga agttcggaca attttagtaa
   105601 atgatgaacc atattttgta ggcaaagacg ttgcgagtgt tttgggttat tcaaacacta
   105661 aagatgcttt gtcgcggcat gtagatttgg aagataagat ggggtcgcga atcacgacct
   105721 caggtcaatc aagagagatg acaatcatca acgaatctgg tttgtacagt ttaatcttaa
   105781 aatcaaaact tccctctgcc aaaaaattta aacgttgggt aacaagtgaa gtgttgccag
   105841 caattagaaa acatggaggt tatctaactc cagaaaaagt agaagaagct ttgcttaatc
   105901 cagatacaat cattcaatta gcaactcaac taaaagaaga aagaactgga agattaatcg
   105961 cagaacaaaa gattgcagag tacgaaccta aaatctccta tttagatagc atattatctt
   106021 ctacagattc agtaacaatt agtcagattg cagcagatta tgggatgtct ccacaacaga
   106081 tgaataaatt acttcataaa ctaggtattc agaaaaaagt cggtaaccaa tggttattgt
   106141 gcaaaaaaca catgaaccaa ggatacacaa aatctcatac aactgagatc ccgaaagccg
   106201 atggtggcac taaaattgta atgaatacca aatggacaca gaaagggcgt ctatttatct
   106261 acgaattact aaaaaaagaa ggatattacc ctcaaatgga tttagaggaa attggttaga
   106321 aaggagtttt agtatgactg acattgcaga aatcactcaa cgagatagag aaaaaatcaa
   106381 agaatatgtc gaaagttcaa agttcttaac ttacaccatg cttgctgaaa gatttggaat
   106441 tagcaaaagc tacttatctt taattttaaa cggtaaaaag acttctgcag aagcaaacag
   106501 aattatagat tcgattatca ctatgtacga attgtaaagg gaggaacagc taatgcaata
   106561 tctagaagca aaaatcccaa ttccagaagg ctatgtaatt atctcccaag tggattatga
   106621 ggagttaaaa aaagctgatg atactggtag atggatgacg ttgccagaag tgctagaacg
   106681 gattaacaga aaatatgatt ggtttacttc tagagtttta aagaacccaa gatatagaaa
   106741 tattatcgat atcgagaaaa acaaaaatgg atttgtctat tatccagttg aaggaagaga
   106801 cacatatcta tttttaagaa gtaaaacact tgaattttta gaaacaaatt tttcggaaat
   106861 cttaaggagg caagcggatg ggaaaattta atagagcgct agtgttcagc gcaccgctaa
   106921 tcatctacgc tttaggactt tggggaagca g
//
LOCUS       DAYYEF010000004        88900 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000004 DAYYEF010000000
VERSION     DAYYEF010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 88900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.004"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            156..2690
                     /gene="secA"
                     /locus_tag="ACHA1B_000354"
     CDS             156..2690
                     /gene="secA"
                     /locus_tag="ACHA1B_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006605 - protein targeting [Evidence IEA];
                     GO_process: GO:0006886 - intracellular protein transport
                     [Evidence IEA];
                     GO_process: GO:0017038 - protein import [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HFM8701150.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            2817..3918
                     /gene="prfB"
                     /locus_tag="ACHA1B_000355"
     CDS             join(2817..2888,2890..3918)
                     /gene="prfB"
                     /locus_tag="ACHA1B_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016149 - translation release factor
                     activity, codon specific [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HFM8701151.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            4023..4709
                     /gene="ftsE"
                     /locus_tag="ACHA1B_000356"
     CDS             4023..4709
                     /gene="ftsE"
                     /locus_tag="ACHA1B_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000910 - cytokinesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HFM8701152.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            4702..5586
                     /gene="ftsX"
                     /locus_tag="ACHA1B_000357"
     CDS             4702..5586
                     /gene="ftsX"
                     /locus_tag="ACHA1B_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease-like cell division protein FtsX"
                     /protein_id="HFM8701153.1"
                     /translation="MIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFMAVI
                     MNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELKKIQ
                     NEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSDRIF
                     QIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFF
                     LEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMVGIG
                     VIIGSLGSIISMRRFLKF"
     gene            5738..7186
                     /gene="cls"
                     /locus_tag="ACHA1B_000358"
     CDS             5738..7186
                     /gene="cls"
                     /locus_tag="ACHA1B_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA];
                     GO_function: GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA];
                     GO_process: GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HFM8701154.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
     gene            7523..8380
                     /locus_tag="ACHA1B_000359"
     CDS             7523..8380
                     /locus_tag="ACHA1B_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HFM8701155.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQAENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            8495..9415
                     /gene="pstC"
                     /locus_tag="ACHA1B_000360"
     CDS             8495..9415
                     /gene="pstC"
                     /locus_tag="ACHA1B_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HFM8701156.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            9415..10299
                     /gene="pstA"
                     /locus_tag="ACHA1B_000361"
     CDS             9415..10299
                     /gene="pstA"
                     /locus_tag="ACHA1B_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HFM8701157.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            10314..11120
                     /gene="pstB"
                     /locus_tag="ACHA1B_000362"
     CDS             10314..11120
                     /gene="pstB"
                     /locus_tag="ACHA1B_000362"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFM8701158.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            11136..11894
                     /gene="pstB"
                     /locus_tag="ACHA1B_000363"
     CDS             11136..11894
                     /gene="pstB"
                     /locus_tag="ACHA1B_000363"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015415 - ATPase-coupled phosphate ion
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HFM8701159.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            11907..12584
                     /gene="phoU"
                     /locus_tag="ACHA1B_000364"
     CDS             11907..12584
                     /gene="phoU"
                     /locus_tag="ACHA1B_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006817 - phosphate ion transport [Evidence
                     IEA];
                     GO_process: GO:0030643 - intracellular phosphate ion
                     homeostasis [Evidence IEA];
                     GO_process: GO:0045936 - negative regulation of phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HFM8701160.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            13148..13840
                     /locus_tag="ACHA1B_000365"
     CDS             13148..13840
                     /locus_tag="ACHA1B_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFM8701161.1"
                     /translation="MLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAIL
                     FVVIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYL
                     TRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVI
                     GSMANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIA
                     VLFFLAVRRLKK"
     gene            13837..14604
                     /locus_tag="ACHA1B_000366"
     CDS             13837..14604
                     /locus_tag="ACHA1B_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HFM8701162.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            14704..16272
                     /gene="liaX"
                     /locus_tag="ACHA1B_000367"
     CDS             14704..16272
                     /gene="liaX"
                     /locus_tag="ACHA1B_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HFM8701163.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENGEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            16448..16756
                     /locus_tag="ACHA1B_000368"
     CDS             16448..16756
                     /locus_tag="ACHA1B_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0080135 - regulation of cellular response
                     to stress [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HFM8701164.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            16756..17106
                     /locus_tag="ACHA1B_000369"
     CDS             16756..17106
                     /locus_tag="ACHA1B_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HFM8701165.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
     gene            17272..18210
                     /gene="hprK"
                     /locus_tag="ACHA1B_000370"
     CDS             17272..18210
                     /gene="hprK"
                     /locus_tag="ACHA1B_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006109 - regulation of carbohydrate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr(Ser) kinase/phosphatase"
                     /protein_id="HFM8701166.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            18225..19055
                     /gene="lgt"
                     /locus_tag="ACHA1B_000371"
     CDS             18225..19055
                     /gene="lgt"
                     /locus_tag="ACHA1B_000371"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFM8701167.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            19099..20124
                     /locus_tag="ACHA1B_000372"
     CDS             19099..20124
                     /locus_tag="ACHA1B_000372"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFM8701168.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            20139..21077
                     /gene="galU"
                     /locus_tag="ACHA1B_000373"
     CDS             20139..21077
                     /gene="galU"
                     /locus_tag="ACHA1B_000373"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFM8701169.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            21202..21651
                     /locus_tag="ACHA1B_000374"
     CDS             21202..21651
                     /locus_tag="ACHA1B_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HFM8701170.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            21644..22258
                     /locus_tag="ACHA1B_000375"
     CDS             21644..22258
                     /locus_tag="ACHA1B_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFM8701171.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(22321..23424)
                     /locus_tag="ACHA1B_000376"
     CDS             complement(22321..23424)
                     /locus_tag="ACHA1B_000376"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004177 - aminopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HFM8701172.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            23634..24635
                     /gene="ccpA"
                     /locus_tag="ACHA1B_000377"
     CDS             23634..24635
                     /gene="ccpA"
                     /locus_tag="ACHA1B_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0001228 - DNA-binding transcription
                     activator activity, RNA polymerase II-specific [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HFM8701173.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            24989..25384
                     /locus_tag="ACHA1B_000378"
     CDS             24989..25384
                     /locus_tag="ACHA1B_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701174.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            25381..26637
                     /locus_tag="ACHA1B_000379"
     CDS             25381..26637
                     /locus_tag="ACHA1B_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HFM8701175.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            26649..26972
                     /locus_tag="ACHA1B_000380"
     CDS             26649..26972
                     /locus_tag="ACHA1B_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701176.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            26965..27231
                     /locus_tag="ACHA1B_000381"
     CDS             26965..27231
                     /locus_tag="ACHA1B_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701177.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(27394..29739)
                     /locus_tag="ACHA1B_000382"
     CDS             complement(27394..29739)
                     /locus_tag="ACHA1B_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HFM8701178.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            30018..30920
                     /locus_tag="ACHA1B_000383"
     CDS             30018..30920
                     /locus_tag="ACHA1B_000383"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HFM8701179.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            31131..32906
                     /locus_tag="ACHA1B_000384"
     CDS             31131..32906
                     /locus_tag="ACHA1B_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HFM8701180.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(33215..34801)
                     /locus_tag="ACHA1B_000385"
     CDS             complement(33215..34801)
                     /locus_tag="ACHA1B_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HFM8701181.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            35052..35276
                     /locus_tag="ACHA1B_000386"
     CDS             35052..35276
                     /locus_tag="ACHA1B_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HFM8701182.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            35418..37169
                     /locus_tag="ACHA1B_000387"
     CDS             35418..37169
                     /locus_tag="ACHA1B_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="HFM8701183.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            37169..38953
                     /locus_tag="ACHA1B_000388"
     CDS             37169..38953
                     /locus_tag="ACHA1B_000388"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701184.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            39288..40139
                     /gene="licT"
                     /locus_tag="ACHA1B_000389"
     CDS             39288..40139
                     /gene="licT"
                     /locus_tag="ACHA1B_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
                     /protein_id="HFM8701185.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            40236..42122
                     /locus_tag="ACHA1B_000390"
     CDS             40236..42122
                     /locus_tag="ACHA1B_000390"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFM8701186.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(42163..43065)
                     /locus_tag="ACHA1B_000391"
     CDS             complement(42163..43065)
                     /locus_tag="ACHA1B_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFM8701187.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            43295..44698
                     /locus_tag="ACHA1B_000392"
     CDS             43295..44698
                     /locus_tag="ACHA1B_000392"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFM8701188.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            44698..46131
                     /locus_tag="ACHA1B_000393"
     CDS             44698..46131
                     /locus_tag="ACHA1B_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HFM8701189.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     NEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            46276..47202
                     /gene="trxB"
                     /locus_tag="ACHA1B_000394"
     CDS             46276..47202
                     /gene="trxB"
                     /locus_tag="ACHA1B_000394"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004791 - thioredoxin-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HFM8701190.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            47416..49143
                     /locus_tag="ACHA1B_000395"
     CDS             47416..49143
                     /locus_tag="ACHA1B_000395"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFM8701191.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            49159..49509
                     /locus_tag="ACHA1B_000396"
     CDS             49159..49509
                     /locus_tag="ACHA1B_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFM8701192.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(49603..50463)
                     /locus_tag="ACHA1B_000397"
     CDS             complement(49603..50463)
                     /locus_tag="ACHA1B_000397"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="HFM8701193.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            50555..50983
                     /locus_tag="ACHA1B_000398"
     CDS             50555..50983
                     /locus_tag="ACHA1B_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFM8701194.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            51145..51321
                     /gene="rpsU"
                     /locus_tag="ACHA1B_000399"
     CDS             51145..51321
                     /gene="rpsU"
                     /locus_tag="ACHA1B_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HFM8701195.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            51348..51794
                     /locus_tag="ACHA1B_000400"
     CDS             51348..51794
                     /locus_tag="ACHA1B_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HFM8701196.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(51950..53329)
                     /gene="brnQ"
                     /locus_tag="ACHA1B_000401"
     CDS             complement(51950..53329)
                     /gene="brnQ"
                     /locus_tag="ACHA1B_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFM8701197.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            54035..55006
                     /locus_tag="ACHA1B_000402"
     CDS             54035..55006
                     /locus_tag="ACHA1B_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HFM8701198.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            55030..57222
                     /locus_tag="ACHA1B_000403"
     CDS             55030..57222
                     /locus_tag="ACHA1B_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing metalloprotein"
                     /protein_id="HFM8701199.1"
                     /translation="MLNKTLQKLQKKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            57239..57715
                     /gene="ybeY"
                     /locus_tag="ACHA1B_000404"
     CDS             57239..57715
                     /gene="ybeY"
                     /locus_tag="ACHA1B_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HFM8701200.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            57699..58094
                     /locus_tag="ACHA1B_000405"
     CDS             57699..58094
                     /locus_tag="ACHA1B_000405"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFM8701201.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            58109..59008
                     /gene="era"
                     /locus_tag="ACHA1B_000406"
     CDS             58109..59008
                     /gene="era"
                     /locus_tag="ACHA1B_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HFM8701202.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            59151..59963
                     /gene="recO"
                     /locus_tag="ACHA1B_000407"
     CDS             59151..59963
                     /gene="recO"
                     /locus_tag="ACHA1B_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HFM8701203.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQLMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            60349..61266
                     /gene="glyQ"
                     /locus_tag="ACHA1B_000408"
     CDS             60349..61266
                     /gene="glyQ"
                     /locus_tag="ACHA1B_000408"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HFM8701204.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            61268..63343
                     /gene="glyS"
                     /locus_tag="ACHA1B_000409"
     CDS             61268..63343
                     /gene="glyS"
                     /locus_tag="ACHA1B_000409"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HFM8701205.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            63728..64507
                     /locus_tag="ACHA1B_000410"
     CDS             63728..64507
                     /locus_tag="ACHA1B_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701206.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
     gene            64548..65492
                     /locus_tag="ACHA1B_000411"
     CDS             64548..65492
                     /locus_tag="ACHA1B_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFM8701207.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            65508..66287
                     /locus_tag="ACHA1B_000412"
     CDS             65508..66287
                     /locus_tag="ACHA1B_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Wzz/FepE/Etk N-terminal domain-containing
                     protein"
                     /protein_id="HFM8701208.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPTQPKATNDKTAPSRRSRSRV"
     gene            66300..66998
                     /locus_tag="ACHA1B_000413"
     CDS             66300..66998
                     /locus_tag="ACHA1B_000413"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004713 - protein tyrosine kinase activity
                     [Evidence IEA];
                     GO_function: GO:0004715 - non-membrane spanning protein
                     tyrosine kinase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HFM8701209.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            67026..67790
                     /locus_tag="ACHA1B_000414"
     CDS             67026..67790
                     /locus_tag="ACHA1B_000414"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0045227 - capsule polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CpsB/CapC family capsule biosynthesis tyrosine
                     phosphatase"
                     /protein_id="HFM8701210.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            67835..68524
                     /locus_tag="ACHA1B_000415"
     CDS             67835..68524
                     /locus_tag="ACHA1B_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFM8701211.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            68930..69040
                     /locus_tag="ACHA1B_000416"
     CDS             68930..69040
                     /locus_tag="ACHA1B_000416"
                     /inference="COORDINATES: protein motif:HMM:NF020874.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HFM8701212.1"
                     /translation="MNPNGYEWLRAKGSYPVPKYCNYSETLMEWYQLIIT"
     gene            69599..69879
                     /locus_tag="ACHA1B_000417"
                     /pseudo
     CDS             69599..69879
                     /locus_tag="ACHA1B_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003697748.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
     gene            70386..71636
                     /locus_tag="ACHA1B_000418"
     CDS             70386..71636
                     /locus_tag="ACHA1B_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HFM8701213.1"
                     /translation="MKKQYNIAVAGTGYVGLSIATLLAQHHKVTAVDIIPEKVELINN
                     RKSPIQDDYIEKYLAEKELNLTATLDAKAAYQSADFVVIAAPTNYNSRTQHFDTSAVE
                     AVIRLVMEVNPDAIMVIKSTIPVGYTASVRVKTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMDDERLVEDAHTFATLLQEGAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPENLIEAIVESNRTRKDFIADRVLQMAGYYNYAEANQYDAGKEKPVVIGVYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPTLKDGETFFGSKVVNDLEQFKAMCDSVI
                     ANRYDACLDDIKEKVYTRDIFQRD"
     gene            71655..72665
                     /locus_tag="ACHA1B_000419"
     CDS             71655..72665
                     /locus_tag="ACHA1B_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HFM8701214.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFKENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSAELSYSRTERVTSIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALEGKYADKKKLADEAIYLERVLCNEAGGWQDQIAASYGGFNRI
                     NFNVDGYEVLPVIISPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAILTDKNRNLDDFGRQLDVTWRLKKGTGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQDAVRWAMRDLMYIPFEFENGGTRVIHYTPETYIEKQ
                     NG"
     gene            72675..73328
                     /locus_tag="ACHA1B_000420"
     CDS             72675..73328
                     /locus_tag="ACHA1B_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFM8701215.1"
                     /translation="MLAEKLNKHIDLLIKRYPTLETIKQDIIDGYLIMEECYLNGGKL
                     LVAGNGGSAADSEHIAGELMKRFKTPRPVSKEFADKLVAIDPVRGPELAKNLECGLTA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRSGDVFLGISTSGNSKNIMSATVVARA
                     LGIKVIGLTGAKGGELATVADVCVKAPEVETYMIQEYHLPIYHCWCLMLEDKFFGNE"
     gene            73347..74345
                     /locus_tag="ACHA1B_000421"
     CDS             73347..74345
                     /locus_tag="ACHA1B_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFM8701216.1"
                     /translation="MKKTIMVTGGCGMIGSNLVKRLVKEGCWDVYVADNLWRGKLEYL
                     NDEDGHPVIDLDTHFFNADLTDYEQAKKVIGTTEYVVHLADVVAGIDYVFKNQGELFR
                     INNLINSNVFDCCRKAGKEKIKGVIYVGTVCSFPLTRQNTLNPEPLREEELFPALPES
                     AYGWSKLMGQLEMGYLEKETGIPCCILMLHNVYGTPTDFGERSQVIPALIRKAINNPE
                     EPFNVWGSGEQGRAFIHVNDIVNALVLALDKGWGHGHIQIGPSHCTSIKEIAYKIIEI
                     SGKDIKPFFDTSKPEGDKARCADYSKAKEILDWEPTVSLEEGLRESYNWIEKQIKG"
     gene            74421..75182
                     /locus_tag="ACHA1B_000422"
     CDS             74421..75182
                     /locus_tag="ACHA1B_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HFM8701217.1"
                     /translation="MEKNMYKRKRDFTVCGIVGVCATTKNEFVREVFSMPTSPVSATV
                     DLVGVPAIISAKENPKIAEMYSQATMAAIDGMPIVKIGRRKGFTCERCAAPDIMGMVF
                     EEGVRQGKTHYFYGGKDNEVLNKLRANLERDYPGIKIVGMYSPPFRPLNEEEDSKICE
                     EINNLNPDFLWVGIGAPKQEMWMWEHQKKIHNTVMFGVGAGFNFFAGTLEKAPEWMEK
                     ASLEWLFRLVKEPRRLWRRYILGGIKYIYYTIESK"
     gene            75200..76306
                     /locus_tag="ACHA1B_000423"
     CDS             75200..76306
                     /locus_tag="ACHA1B_000423"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFM8701218.1"
                     /translation="MKILIVVTMTNNFGKKGSYNSQEIGLARGLAELGHEVIVYKSVK
                     SDEEVGTEQLSNTAMIHYIKCRYVGSNGFLSTKNFDKNADVLIQFADLQLSVPHVYSW
                     TVKNGIKYIPYNGITRSQSGNKYIKTIIEILAHRNYKIYKKNGCVAKNDRVSEKLVQL
                     GVNKVKLAPVCVDFEQLHKNYEAIDFTTLREKWNIPRNVRVILYVGRFEKDKRPLDMI
                     SLFNKLDEHNYLLMVGTGALLEQTKQQINLLGLQNRVKIIERIPNKDIWELYCLSDVF
                     VNLNYTEIWGMVLLEAMYYRLGIIAVNAPGPQNIILDNRYGMLAKSDDEILTFLKDGR
                     FTNDIIDAAYQRVTTEFRWSKSGEIMLSMLEGDK"
     gene            76728..77183
                     /locus_tag="ACHA1B_000424"
     CDS             76728..77183
                     /locus_tag="ACHA1B_000424"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HFM8701219.1"
                     /translation="MNAYKLYKVERWFYLHKMEFFAKIVKALIYVLHNSSISYQTEIG
                     DNCKFLYGGIGCVIGKDTKIGNHVIIGTNVLTGGRSNKPGMPTIGNNVYIATGAKILG
                     NITIGDNVIVGANAVVINDVEPNCSVGGVPARVLKKDIDVNDYCSLNRY"
     gene            77197..77970
                     /locus_tag="ACHA1B_000425"
     CDS             77197..77970
                     /locus_tag="ACHA1B_000425"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family A protein"
                     /protein_id="HFM8701220.1"
                     /translation="MLYFVIPLMSAKAANNWEMVSTLFNRTLWSCYNQTDPDFKIIVA
                     CHEIPKLTHEYDDRVEFIQVSEKDAPIPTNQDEKMIDKGYKTHALAMRLRELGGGFAM
                     MVDADDLVSSHLAEYVNSHPQENGFYVKTGYVYFVGDDYMKVLPKFSSGSACIVKYAV
                     EDLPEAYPEVMTANCDDNPWIIRKRHGGVVPACEEQGRPLKPLPFKAAVYVLGTGDNH
                     SLYGKTTKYQTKMREILEMFIAKRKIKGKLKAEFSVDWL"
     gene            77981..79087
                     /locus_tag="ACHA1B_000426"
     CDS             77981..79087
                     /locus_tag="ACHA1B_000426"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFM8701221.1"
                     /translation="MKVLMCESQMPENWYSFDLSKELNQYVDLTLLCKRDVPPLDPKI
                     KSKHILYHKSTNKVFSALVFLKSLFLIWKEIRFGDYDIVHLQLMKSLKYEGGLYVLCK
                     RHYKKLIMTVHNVLPHEVREKDRQEHFNIYSNCDGFIVHNRVTEQHLYAEFPELNAKS
                     YVCPHAIYGDVKHISRAYDKDKFEFILFGQIRPYKGIDVLLNAITELPMDVRKKVHFT
                     IAGQQHPKQDSTDYKKMIEDLKVSDCVLYKPERISDEEMDSMFRNADAAIFPYKEIYG
                     SGALLMAYTYCLPTIVSNVPAFMEETEEGKIGLLFENLNSKSLADTIVKYVNLSPAEK
                     SKIEDDIYELVNRKYTWAASAKLTYEAYKQILNE"
     gene            79118..80353
                     /locus_tag="ACHA1B_000427"
     CDS             79118..80353
                     /locus_tag="ACHA1B_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701222.1"
                     /translation="MQISKWKIIQFLMVFLMIISSSILKPLGGWLGETMNVRLVTVIL
                     AIVCLLIASLPAFRKNRYLNFCTLLICVVIIAAYIYSDKTIWVKSRESMSLYYVLLAY
                     PLFCTLINQAWNLDSMLNTICGVTFLSYILRTSISLIQKFSGVLLYENIYRECAPENW
                     YRGGFLRINPPCFTIIIIPIALYMIERQVVARRKVKYYLLIASALAYSAVIHGSRSVL
                     VYQIIVLGCYILFKKGSSKRKIAMWVLAGLLVVIFINSTMFSTFVETFTNSTGEYAGS
                     AESRFASVWFFIPKFLQSPLFGTGILTGEEFTFILPGGVRGHLSDIGFFYTITQYGVG
                     ILIFDILFIIKGFKTALLASKVGMTGYQYLAFGITLNVLLTGINIDWFYPIFTPAIPV
                     CLAVIEYIYQECRSVANIE"
     gene            80378..81487
                     /locus_tag="ACHA1B_000428"
     CDS             80378..81487
                     /locus_tag="ACHA1B_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WavE lipopolysaccharide synthesis family
                     protein"
                     /protein_id="HFM8701223.1"
                     /translation="MNKKEILYNILKKYENLPYVFRNMFGHNISKLVSWKLTADCATV
                     EENSEVYAAFQLRSKDMSDVPVMGLVNCCKDVAIVMQGPLCLKDDFSYNTLAYYKKCY
                     PNALIILSTWKDEDIKALKRIEDLGVIVICSEKPEKPGHLNINYQVGNTLPGIVRAKQ
                     LGAKYVCKTRTDQRIYHPNAMAFFCSLLEQYPVNNEDDWKLIQNQRLLLLSMPYGDMF
                     FPYCLSDFLYFGDVDDMINLFSIPSDVREKGAVSRGVSRREISENNLAPEVQLLRSYI
                     SRMGGNEECSIRAYWEFVKNHVITINKNQIDLYWHKYVGRYSNNTIYGTYYIDDSQDA
                     LHCYNFDFINWLNLYTGKYEYKAEYEKYMDFVWEE"
     gene            81529..82863
                     /gene="gmhB"
                     /locus_tag="ACHA1B_000429"
     CDS             81529..82863
                     /gene="gmhB"
                     /locus_tag="ACHA1B_000429"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016791 - phosphatase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HFM8701224.1"
                     /translation="MKTVIMAGGRGSRISELFPDIPKPMIPIDGIPVLERELCSLRDQ
                     GFNDIILTVSYLHEKIEEHFGDGSKLGIKIKYFIEKTPLGNAGALYFLLDELGDEPFL
                     LLNADAVFDVDFRQMIRFHVENNADVTLFTHPNSHPYDSGLIISDDNKKVLQWLAKED
                     QRPEYYKNRVNAGLHVINPKVLRENPLMEIVNKSIVEGGGLPYKIDLDRMILKPLANT
                     GRMYCYDSPEYVKDMGTPDRYRAVIKDFQKGIIVGKNLSNPQKAIFLDRDGTINKYVG
                     FLRNAEEFELIDGVSEAIKIINSLGFLCIVITNQPVIARGEVTVDELNSIHNKLETML
                     GHAGGFLNGIYYCPHHPHKGYAGEVIELKIDCNCRKPKPGLLLEASKDFNINLSQSFM
                     VGDSESDVIAGKNAGCKTVLITEDITLPANYGQDYSVCSLLEFVKNHLCTMQ"
     gene            82898..84535
                     /locus_tag="ACHA1B_000430"
     CDS             82898..84535
                     /locus_tag="ACHA1B_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HFM8701225.1"
                     /translation="MKVLIPAAKVVEKELQSIGMLPAIIYPINKKIVFDYLYNQYNAI
                     CDSLDIICYEKADKVHRRLKNYHDSRIHICDLPELGDLGQTVYFGLSDEDEPVLINFA
                     DTIVMESMSDIEMDTFYYSEDFVSSTWTYFKINEGIITDIHDKEEAYVSDKREKLFIG
                     VFMFSSSKLLKSCLREAVESRKQGGINSFYRALQLYSERCPLKAVRTEKWFDIGHIDK
                     YYNTKLEVKAREFNHISIDKDRGILKKTSDDKDKFIGEIKWYLKLPADIEYVRPRIFD
                     YSTSYVAPYVDMEYYAYHTVHELYLYGDLKYNQWHDLFSRIKFICSDFKRYTLKDEKI
                     RESLEDMYLRKTMQRFQKLSEDKRFSAFFEKQIQINGRKFISLTGVIELLKNLIPSML
                     YDVNEFCIIHGDLCFANMMVDSNCSFVKVIDPRGKFGKYDIYGDSRYELAKLFHSLDG
                     KYDYIIKDLFTVEYDTECAVIDYTINTRVRDYDLFELFKSVFSDEIKDDFDKIVLIEA
                     LLFLSMIPLHGESFDHQIVMLATGMELLARVSNKVIL"
     gene            84637..85032
                     /locus_tag="ACHA1B_000431"
     CDS             84637..85032
                     /locus_tag="ACHA1B_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HFM8701226.1"
                     /translation="MYSEYSFVFDIDGTLCPIKKKDERYEDLVPYENMVEKLRFYKEN
                     GAKITLFTSRNVNSYKGNLGMINANTAKVLLAWLDKWDIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLRCSVDELNEICNSSKKRF"
     gene            85050..85781
                     /locus_tag="ACHA1B_000432"
     CDS             85050..85781
                     /locus_tag="ACHA1B_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM8701227.1"
                     /translation="MEKKMTVIITMAGLGSRFRKIGYAVPKYMINAKGRTLFDWAMDS
                     LVGYNKNVDKYIFVVRQEDNASAFIKEHCAYFGIENVEVIEIDYMTDGQATTCMLAIP
                     YCNQDNEIMVYNIDTYVESNEMKYEDICGDGHIPCFHADGDHWSFAKLNDRNEVIEVR
                     EKVRISDNCTLGAYYFSSAKLYKALYEEYYADSSNMEKNEKYIAPLYNFMIKKGLKVT
                     ISIVDAKKVHVLGTPEELNVFLNQE"
     gene            85805..87256
                     /locus_tag="ACHA1B_000433"
     CDS             85805..87256
                     /locus_tag="ACHA1B_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFM8701228.1"
                     /translation="MTSNNLIVKTLSRYKNTPLPVKAALWFMVCGFLQRGVSMITTPI
                     FTRVLSTEQYGLYSTYLSWESLLLMITSLSLFKAMMNLYVKYDNQEHILSTVSGLTLV
                     LTIFWFVIAIFIKDILAEILGLTPVLVVCMFSYFIFQAEIQCWSLHKRYIYDYKTLLV
                     ATLAVTVGSSVVGCLAVLFISPTAEARALMNVLVTGVVGVAVYISVFRRCKDFKDNEV
                     WNFAVVFCVSLMPHYLSEFILNGSDKIMINYLCGSSDVAIYSVAYSIGALINLVTNSV
                     NSTFAPYQYQKIKSGEYDLLSKRANEVLGLVAAMLFALMLFSKEIVLIFGGQKYIDSV
                     NLIVPICIGIYFNYMFQLFARVQEYFEKKLTVVIPSVLCAIMNIVLNYVFIKLYGYQA
                     VAYTTVFSYMFFCVIHYIFYRKVCKELLDGKNIYDVRGILLISAITIAGGILISIINK
                     FDFIKYLIIAIACVAAIIFRKRLLLLVRRIMSK"
     gene            87282..87893
                     /locus_tag="ACHA1B_000434"
     CDS             87282..87893
                     /locus_tag="ACHA1B_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFM8701229.1"
                     /translation="MIDIISAITVNVLTALYQPFLFAVLTAYLFMYWYLFIVDNSRDP
                     KNLKDSVLIWLRYFKASSKFRRLFFLAFYFTLILFKTLLNRNMWMNPLSNVIGQWSLY
                     IIDNATGESRLTTECVENTMLFIPFCMLLLWWRDIKCDIIRTIYVGIKYVFLFSLSIE
                     FTQLFFRLGTFQLSDLFYNTLGGLIGALLYWLFYRLNKYIDLK"
     gene            88075..88590
                     /locus_tag="ACHA1B_000435"
     CDS             88075..88590
                     /locus_tag="ACHA1B_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HFM8701230.1"
                     /translation="MVVVMVKVFDIIKFSDFRGYTAVALDNETLFSIGIEFHIKQINQ
                     GFSHNKYTMRGLHYQSGEHAQGKIVMCLHGEIMNIALDIRQGSSTYGCVYVNTLSESN
                     GKCAYIPRGYAHGYLTMEDNTLVQWCVDNDFNSNAAKCISYESVDIEWPVSRQCFVIS
                     EKDKNVERLSF"
     gene            complement(88725..>88900)
                     /locus_tag="ACHA1B_000436"
     CDS             complement(88725..>88900)
                     /locus_tag="ACHA1B_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFM8701231.1"
                     /translation="TVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQ
                     RRFEGTLRYSLGY"
BASE COUNT        29166 a        15044 c        19112 g        25578 t
ORIGIN      
        1 gtttcctcct cttttagatg aaatatgaat aaattatgaa gttcttactt taatacgctt
       61 aagatatttc aattatctat aactaatgat aaaatgaaaa gtaaagtcta catagtctgg
      121 ataatacaca gaaggaaaag gagattacac aacgcatggc caatttgatt cgttcactta
      181 tcgaaaacga taagaaagaa ctaaaacgtt tagatagcat tgcaaaaaaa gttgaagcat
      241 acgctgacca aatggcagca ttaactgatg aacaattaca ggcaaaaact gctgaattca
      301 agggcagata ccaaaaagga gaaacattag atcaattact tccggaagct tttgcagtcg
      361 tccgagaagc agcaaaacgt gtattggggt tatatccata ccacgtacaa ttaatgggtg
      421 ggatcgtgct tcacgatggg aatatccctg aaatgcgtac tggtgaaggt aaaaccttga
      481 ctgcaacgat gccggtgtat ctgaatgcgt tgactggcga aggggtccac gtagttaccg
      541 tcaatgaata tttagcaacc cgtgactcga cggaaatggg cgagctttat aatttcttag
      601 gattgacagt tgggttgaat atcaactcaa aatcttcgga tgaaaaacgc gaggcttata
      661 attgcgatat cacttatagc acgaataatg aattaggatt tgactatttg agagacaaca
      721 tggtcgttta ccgtcatcaa atggtacaac gtccgctgaa ttatgccatt gtcgatgaag
      781 ttgactcgat cttgattgat gaagcgagaa cgccgctgat catttcaggg caagcagaaa
      841 aatcaacagc tttatataca agagcagaca acttcgtgaa acgtttgaaa gaagaagaag
      901 attataaaat cgatatacaa tcaaaaacaa tcagtttaac tgaagcaggg atcgaaaaag
      961 ctgaagaaac attcggtttg gacaacttat atgacattga aaatactgca ttgacccatc
     1021 acttggatca agcattgaga gccaactaca tcatgctttt agacatcgat tatgttgttc
     1081 aagatggaaa agtattgatt gttgaccaat ttacgggtcg gatcatggat ggacgccgtt
     1141 attcagatgg tcttcatcaa gcgatcgaag ctaaagaagg cgtagagatc gaagacgaaa
     1201 cgaaaacgat ggcgacgatc actttccaga actatttccg tatgtacaag aaacttgcgg
     1261 ggatgactgg tacagctaag acagaagaag aagagttcag agagatttat aatattcaag
     1321 tataccagat tccgacaaac cgtccggtca tccgtgacga tcgaccagat ttgctttacc
     1381 caacattaca aagcaagttc catgctgtcg tacaagatat caaagatcgc taccgcaaag
     1441 gacagcctgt cttagtcgga actgttgcag ttgaaacatc tgagttatta tcagatatgc
     1501 tgaatcaaga acgtattcct catgaagtac tgaatgcgaa aaatcacttt aaagaagcag
     1561 aaatcatcat gaatgcgggt caaaaaggtg cagtgacgat tgctaccaac atggctggtc
     1621 ggggaacaga tatcaagcta gggcttggcg taagagaact tggtggccta gcagttatcg
     1681 ggacagaacg acatgaatct cgtcgtatcg ataaccagct tcgaggacgt gcaggacgtc
     1741 aaggagaccc tggtatgtca caattctact tgtctttaga agatgatttg atgaaacgat
     1801 tcggttcaga acgaatcaaa gctttcttag atcgaatgaa gatcggtgac gaagatgctg
     1861 tgatccaaag caagatgctg acgaaacaag tagaagctgc acaaaaacgc gtagaaggaa
     1921 acaactacga cacacgtaag aacgtcttgc aatacgatga cgtgatgcgt gagcaacgtg
     1981 aagtaatcta taaacagcgt caagaagtga tcatggaaga aaaaagctta tctaaaccac
     2041 tgatgaatat ggtcaaacgg acaatcagtc gtgtggtaga tgcgcatacg caattagaaa
     2101 aagaaaattg gaatttggaa agtatcgtcg attttgctgg cagcacgctt gtccatgaag
     2161 acagtatttc ccttacagat atcgaaggaa aaacctctca agaaatcaaa gaatatctaa
     2221 acgaacgagc acaagaagta ttcaatacca aagcagctca attgaacgga ccagagcaac
     2281 tgcttgaatt tgaaaaagtc gtgatcttac gtgtcgtgga ctctaaatgg acagatcata
     2341 ttgatgcaat ggaccaatta cgtcagtcaa tcggcttgcg tgcctatggt caaaacaatc
     2401 cattagtcga ataccaaaca gaaggttata agatgttcga agatatggta ggtgccattg
     2461 aatatgaagt cactcgtatc ttcatgaaag ctgagatccg tcaaaacgta caacgtgagc
     2521 aagtttctca aggaacagct tctcactcag aagatggaga tgccaaagaa aacagtaata
     2581 ctagcgcgaa aaaacaacca atccatgtga acaaggttgg tagaaatgat ccttgtcctt
     2641 gtggaagcgg gaaaaaatat aagaactgtc acggaaaaga tgcaaactaa tttctgacag
     2701 caggattggt gagacaaatt cttttttaaa gaatttgtct caccttcttt ctgttatttg
     2761 acgattctgt tagactagat ataataaaaa aagtatagtg aaagaaggaa aaaaacatgg
     2821 aaatatccga aattcgaaat ctcctgacag aaatgcagga aaaggtcaca agcttcagga
     2881 ggtctctttg acttagacca gctggaagaa gacattgcgg aagcagaagc aaaaatggct
     2941 gaacctggtt tttgggatga tagcgaagct gctcaaaaag tgatcagtga aaacaatgca
     3001 aataaagaaa cttatgatca attccattct cttgctgaag aactggaaga aatcgaattg
     3061 atggtggaga tgttgcagga agaacctgat gcagtaatgc aagaagaagc agaagcacgt
     3121 atcaatgcgc tagatgaaaa aatgaatacg tatgaattat ctatgttgtt agatggtcct
     3181 tatgatcgaa acaacgccat cgtcgaattg catccagggg ctggcggaac ggagtcccaa
     3241 gactggggca gcatgctttt acgcatgtat acacgctggg cagagcagca tgggtatcaa
     3301 gtagagacac tagattatca agcaggcgat gaagcaggaa tcaagagtgt gaccctactg
     3361 atcaaaggac acaacgcatt tggctatctg aaatcagaaa aaggtgttca tcgccttgta
     3421 cgtatctcgc cttttgactc agcaaaacgt cgtcatactt ctttttgttc ggtagatgtg
     3481 atgccagagc ttgatgaaac gatcgatata gaaatcaatc cagatgattt gaagatcgac
     3541 acatatcggg cgagtggtgc aggtggtcag cacatcaata agacagaatc cgctgtacga
     3601 atcactcact tgcctacagg aacagtagta gcgagtcagg cacaacgttc acaattgaaa
     3661 aaccgggaac aagcgatggg gatgctgaaa gctaagcttt accaattaga agtggaaaag
     3721 aaagaacaag aagcagctgc actgagagga gaacaaaaag aaatcggctg gggatcacag
     3781 atccgttctt atgttttcca tccatattct atggtaaaag accatcggac aaacgtagag
     3841 acaggaaatg tccaagctgt tatggacgga gatcttgatt tatttattga cggctatttg
     3901 aaaatgcatc tgcaataaga gccctttgtt aaattgaaat aaaattgtaa gattttgcaa
     3961 gcaagttgaa acattgccat gctataatag ctaaagactg aaaaagatat ggagagaacg
     4021 ccatgattga aatgaaggat gtaatgaaga agtactcaaa cggtaccact gctatccgca
     4081 atctctcgat tgtcatcgaa caaggagagt ttgtgtatgt tgttggtccg tctggagctg
     4141 gtaaatctac attcatcaaa ttgatgtatc gagaagaaaa agcttcaaaa ggaactttga
     4201 acgtcgcagg tcatgatcta atagccatca aaaaccgcga agttccttat ctacgcagag
     4261 aaatcggcgt ggtgttccaa gactataaat tattaccaag aaaaacagta tatgaaaatg
     4321 ttgcgtacgc catgcaagtt atcggcagaa aacctcggga tatcaaaaaa cgagtaatgg
     4381 aagtgctgga tcttgttggt ttgaaacaca aagtccgagt ctttcctagc gaattatctg
     4441 gtggggaaca acaacgtgtt tctattgccc gagcaatcgt aaatacacct aaagtactta
     4501 tcgcggatga accgacaggg aatctagatc cggaaaactc atgggaaatc atgaaactat
     4561 tagatcggat caatgcacaa ggaacaactg tcgtgatggc tacacataac agtacgatcg
     4621 taaatacgat tcgacaccga gtaattgcta tcgaaaacgg ccgcattatt cgagaccaag
     4681 cggaagggga atatggatac gatgattaga acctttttcc gccatttatt agaaagtatc
     4741 aagagtttga aacgtaacgg ctggatgaca gtagcttcgg tcagtgcggt aacgatcacg
     4801 ttgactttag ttggtgtgtt catggcggtc atcatgaacg caaccaaact agcacaagat
     4861 atagaaggaa acgtggatgt atctgtgttc gtagacattg gtacaaaaga cgaagagatg
     4921 aaaaaattag aaaaagaatt aaatgactta gatcatgtca aaaaagtcga attttcaagc
     4981 aaagaacagg aattgaagaa aatccaaaac gaaatgggcg attcttggaa attgtttgaa
     5041 ggggataata acccgttata tgatgtatac gtagtaagtg ctaccgatcc ttcttataca
     5101 aaacaagtag cagaaaaagc ggcagatttg aagaatgttt cccgttctga ttacggtggg
     5161 gcttcctcag atcggatttt ccaaattgct ggtgcagttc gaacatgggg attagttgcg
     5221 gcggcattgc tgctgtttgt agcaatgttt ctcatttcta acacgattcg gatcacgatt
     5281 ttatctagac agcgtgaaat tcaaatcatg cgtttagtag gggcaaaaaa tggatatatc
     5341 cgctggccat ttttccttga aggtggttgg atcggcttaa tcggtgccat tcttccgata
     5401 ctgatcatta catttggtta cgcatggttt taccaattga tcaatccgtc attattacga
     5461 tctcattatt cattgatcca tccagaaaat atcgtttgga aaatcaatct tttgatggtc
     5521 ggtattggtg tgatcattgg ttcactcggc tcgatcatct ctatgagacg tttcttgaaa
     5581 ttctagtgtc acaagataaa tataatcaga aagttggacg atttcgttcc agctttcttt
     5641 ttttatcagc taggtggagt aaatggggcg gcttttttct ctttacttta aaaaacaact
     5701 tgggtattct taagttggta gaaaaagagg tgaagccgtg aagattatcg ttgacaattt
     5761 ttttacgatc cttttgatta tgaatatttt gctttccttt attatcgttt ttcgagaaag
     5821 aaaggaaact gcgcaaacat gggcatggct gctcgttttg atgttcattc cagttgtagg
     5881 atttatttta tatatttttt taggaagagg gatttccaaa gagaaaatct ttgatttgaa
     5941 gatccaaggg aaaatcggta agaatctaga aatcgaagaa gataaacaag cattgatgcg
     6001 agggctttat cctcatccgc ctactggaca agtagatgtg aaacaattga tctatatgct
     6061 tactgtattt gaaagtacgc tttatacgac taaaaatgaa atcactttat ttacagatgg
     6121 tcgtgaaaaa ttcgatgcgc tgatcgagga tatcaaacag gcagaagacc atatccattt
     6181 ccaatattat atttaccgca gtgatacatt aggtgaagaa gttcgagagg cattgacaga
     6241 ggcagcaaga cgcggagtaa aagtcagagt ccttcttgat gcatggggtt ccacacaagt
     6301 ttcttctagt ttttttcaga atttgaaaaa agcaggtgga gaagtcgcat ttttctttcc
     6361 tctattcgtt ccgtatatca atcctcgaat caattatcgc aatcatcgta aaatcgtagt
     6421 gattgatggg aaaatcggat atacaggtgg gttcaatgtt ggaaacgaat atctaggatt
     6481 ggtaaagaaa tttggttatt ggcgagacaa tcatctgcgt atctatggag aagcggttta
     6541 caccttgcaa aaccgttttt tgatggactg gaattctcag catacaaaag aagtaggata
     6601 ttcaccggaa tttttcccga ccattcattc tacaggtgat atggctgttc aaatcgtgac
     6661 aagcggacca gataccgaac atgagcaaat caaaatgaca tatttgaaaa tgatttcgtt
     6721 agccaaacgg gagatattga tccaaacgcc gtattacata ccggatggat cgattcatga
     6781 ggcattgaag ttggctcttc tctcaggcgt aaaagtccat atccaaatac ctaacaaacc
     6841 agatcatctt ctcgtttact gggcaacgta ttctttcgct gcagagctga tcgagtatgg
     6901 ggcaagaatc gaaacatatg aaaatggatt tatccatgca aagacgatga ttatcgatgg
     6961 cggcatcgtt tccgttggtt cagctaatat cgacgttcgc tcatttagat tggattttga
     7021 agtcaataca ctgatctatg atgaacgaat ggcttctcgc gtaagaaaag cattctttga
     7081 agattcaaag atttcgacgc atctcacaaa agaagtgtat gaaaaccgag ggatgatgat
     7141 caagatgaaa gaaggattag caagactgat ttcgccgctc ctttaaaata caaaaaggac
     7201 aggagagcca tcaatagatg gaaatctcgc gtcctttttt ctcggggcca tttctgagag
     7261 tacgtcagaa atggagaaag cgtctcgcat gagcgaaatt aactttgggg tatctcttgt
     7321 tttttgggga aagcaagaaa taagctaata tatgctatta aaagagacac atttcaaagc
     7381 cagtatagca tagaaacttt taatgagata gctttttttg caattatgag aatttatttt
     7441 gttatttaat gattttgatt cgttttcatc aagtaatgaa aatgatagaa taaacatact
     7501 ttaggattaa aggagatttc taatgaaaaa actaaaatta ttcttaccaa taataggatt
     7561 agctattctt ttatcaggct gttcaaagtg gattgatcga ggagaatcca ttactgcagt
     7621 tggctcttct gccttacagc ctttagtaga aacggttgct gaaacctacc aggcagaaaa
     7681 tcctggaaaa ttcatcaatg tacaaggggg cggaagcgga actgggttgt ctcaagtaca
     7741 gtcaggagca gtcgatatcg gaaattctga tttgttcgcg gaagaaaaat cagggattga
     7801 tgcttcggca ttagtcgatc atcgagtagc agttgttgga atcactccta ttgtgaacaa
     7861 ggatattggc gtaaaagata tcagtatgga aaacctgaaa aaattattta cgggcgagat
     7921 caaaaactgg agtgaagtcg gtgggaaaga tcagccagta gttatattga accgtgcatc
     7981 aggaagcggg acccgtagta cgtttgaaaa atgggtattg gacggagaaa cagctgttca
     8041 ggcacaagaa caagattcaa gcggaatggt gcgccaaatc gttgcggaca cacccggagc
     8101 aatcagctat gttgcttttt cttacgtttc cgatgatgtg gatacgttga acgttaacgg
     8161 tgtggaacca acagatgaaa atgtgacaac gaacaaatgg acgatttggg catatgagca
     8221 tatgtacaca agagaccatc caaaaaaact gacaaaagaa tttttagact atatcttatc
     8281 tgatgaagta caagataata ttgtcggaga gctaggctat atccctgttt cacatatgaa
     8341 agttgaacgt gattggcaag gaaacattgt taaagagtaa tctttacaca aaatttacaa
     8401 acttagctaa acttttacat gttattaaaa ccaaattgat gttcaatttg tacactgagt
     8461 gagtatgtta aacctgatta agggggagtc atctgtggaa gatgtgaaaa aagtattatt
     8521 aacaaaatca aaacgttcaa aaatggaaca gcgcggaaaa ttcattagtt ttttgtgtat
     8581 cgcgctgatc gtgttggttg tattatctat tttttatttt gtcgctagta aaggattggc
     8641 cacctttttt actgataaga tcaatgtatt tgattttctg tttggtacag attggaatcc
     8701 aagccaaata ggagcaaatg ggaaacccat ggtaggggca ttgcctatga tcacaggttc
     8761 atttattgtg acctttttat ctgctattgt tgccacacca tttgctattg gagcagcagt
     8821 gttcatgacg gagatttctc ctaaaaacgg aacgaagatc ttgcaaccgg tcatcgagct
     8881 acttgtaggt attccgtctg tcgtttacgg atttatcggt ttatctgtta tcgtgccttt
     8941 tgtcagaagt atctttggcg ggacagggtt cggtatctta gctggtacat ttgtgttatt
     9001 cgttatgatc ttaccgactg tcacaacgat gactgtggat gcattaaagg cagtgccgcg
     9061 acactatcgg gaagcttcat tagcgctagg tgccacaaga tggcaaacaa tctacaaagt
     9121 ggtgctgcga gcagcagtgc ccggaatttt aacagcagtc gtttttggta tggctcgtgc
     9181 gtttggcgaa gccttagcta tccaaatggt tattggtaat gcggcattaa tgccaacagg
     9241 acttactact cctgcttcta cattgacgtc catcttgaca atgggaatcg gaaatacaat
     9301 catgggaaca gttgaaaata atgtgttatg gtcattagcg ctgatcttgc tattgatgtc
     9361 attattcttt aatatcgtga tccgtatgat tgggaagaaa ggagagctga aataatgaac
     9421 gcaaaacgct cagataaaat tgctacaggt gttctatatg tggtttcagg gatcatcgta
     9481 ttgatcttag cagctttatt actttatatc ttagttcgag gaataccgca catttcatgg
     9541 tcattcttga ctgaaccttc caaagcctac caagaaggcg gtgggatcgg gattcaatta
     9601 tttaactcga tttatttgct tttgattacc atgatcatca gttttcctat ctctttaggt
     9661 gcgggtatct acctttcgga atatgccgga aaaaactggc tgacagacgt gatccgtacg
     9721 tctatcgaaa tcttgagctc tttgccttct gttgttgtcg gtttattcgg tttcttggtt
     9781 ttcgttattc aattccagta tggtttctca atcatttctg gtgcattagc tttgaccgta
     9841 ttcaacttgc ctcttttgac tcgaacggtc gaggaatctt tacaagcggt ccattacaca
     9901 caacgagaag ctggattggc gttaggtttg tcacgctggg aaacagtgat aaaagtggtt
     9961 gttccagaag cgacaccagg aattttgact ggtgtgatcc taagttcagg aagaattttt
    10021 ggtgaagctg ccgcattgat ttatacagct ggtcaaagcg cgccagcatt agattttacg
    10081 aactggaatc cattaagtgt ttctagtccg atcagcattt tccgccaagc tgaaacactg
    10141 gctgtccata tttggaaaat caacacagaa ggtacgatgc ctgatggtgt ttctgtttcg
    10201 gctggcgctt ctgccgtgtt gatcattgct gttttactgt tcaacttcgg cgctcgtgcg
    10261 attggcaaac gattataccg aaaaatgact tcagcctaag gagaagaagt aaaatgaaaa
    10321 aatataattg gaatgaaaca aatgtcatta ccatgccaaa agataaggaa gttgcattat
    10381 atacgaatga tctgcatgtt tggtatggcg acaatgaagc aatcaaggga gtggatctag
    10441 aattcgaaaa aaataagatc actgcattga ttggtccctc tggctgcgga aaatccacgt
    10501 atcttcgttc tttgaatcgt atgaatgatg ggattgctaa tacgaaaatt actggaaaga
    10561 ttatgtataa agacgtggat atcaatgcgc ctcaagtgga tgtttatgaa atgcgtaaac
    10621 ggatcggcat ggtgttccaa cgccccaacc cttttagcaa atcgatttat gacaatataa
    10681 cttttgcttt gaaacagcat ggtgaaaaaa acaaaaagaa attagatgaa atcgttgaaa
    10741 caagcttgaa acaagcagct ttgtgggatc aagtaaaaga tagcttggat aaaagtgcct
    10801 tggctttatc tggcggacaa cagcaacgtt tgtgtatcgc tcgtgcaatc gcgatgaaac
    10861 ccgatatctt gctgttagac gagccggcaa gtgccttgga tcctatttcg acaggaacgg
    10921 ttgaagaaac acttgtaaac ttgaaagaag actacacgat cattatcgtg acgcataata
    10981 tgcaacaagc agctcgtatc agcgactata ctgccttttt ctatctagga aaagtaatgg
    11041 aatatgacaa aacaaacaag atatttacca gaccaaaaat tcaggcaacc gaagattatg
    11101 tgtccggtca ttttggttaa gacggaggcc tcaacatgac aaaagaaatt atctcatcca
    11161 aagatcttca tctgtattat ggaaagaaag aagcactaaa gggaattgat ctaagtttca
    11221 atcaaggtga aatcacagcg atgatcggtc cttctggttg cgggaaatct acctatctac
    11281 gttcgttgaa tcgaatgaac gatctgattc caaatgtaac gatcaccgga agtgttttat
    11341 ataaagacaa agacatctat ggtccgaaaa cagatgttgt tgaactaaga aaagaaatcg
    11401 gcatggtgtt ccaacagcca aatccatttc ctttttctat ttatgaaaat gtcatctatg
    11461 gattgaagtt aaaaggtgaa aaagataaaa aagtccttga tcaagtagtg gaagaaagtc
    11521 tgaaggcagc gtccgtttgg gaggatgtga aagataaact gcataaaagt gccttgtctt
    11581 tatccggtgg gcagcagcag cgtgtatgta tcgcacgtgt tttggcagtg aatcccgaaa
    11641 tcatcttatt ggacgaacca acaagtgcac ttgaccctgt ttctactggg aaaatcgaaa
    11701 gtatgctgtt agaattaaga gagcggtata cgatgatcat cgtgacccat aatatgtctc
    11761 aagcttcacg tatttcagat aagacggcat tctttttaga tggtcacttg atcgaataca
    11821 acgatacgaa gaagatattc atgaatccag aaaaacaaga gacagaagat tatatttcag
    11881 gtcgatttgg ataaggagga aacggaatgc tacgtacaca atttgaagaa gaattgctga
    11941 atctccataa tcagttctac gaaatgggga tgatggtgag cagcgctgtg cacaagtcag
    12001 ttcgtgcata catcaaacac gataaaatct tagctcaaga agttatcgaa aacgatataa
    12061 atatcaataa tatggaaacg cgtttggaga agaaaagttt tgaaatgatt gcattacaac
    12121 agccagttac aactgacttg cgtatgatta tcacggtcat gaaagctagc tctgatttag
    12181 aacgtatggc cgatcatgcg gtgtccgttg ctaaatccac aatccgcgta aaaggacaga
    12241 cgagaatacc ggaaatcgaa aaagagatct ccgatatgtc cgattacgtg aaaaaaatgg
    12301 tggacaacgt cctagttgcg tatgtcaaaa cagacgaaaa agatgcgcgt acaatcgcca
    12361 atatggatca aagagtcaat gactatttca atcgaatcta taatgcaacc atcaaaaaca
    12421 tgcaagaaaa tcctgaaaca gtcatcagtg gcacagacta tttgaatgtt gccagctatc
    12481 tagaacgaat cggagactat gtgacaaaca tctgtgaatg gatcgtctac ttggctacag
    12541 ggaaaatcac tgaattaaat acgaaccaca atgagatttt ctaaactgaa gttgtgattc
    12601 tgctgtttat ttaggaaaag aggttgtgaa atcagcgttt tgtcctgagt attagagaaa
    12661 caaacggtaa aatagttcct catattttgc cgttttttga gctaataccg aaggtcagct
    12721 gattgaacac cgtttattct ggaaaagggt ttgtgacaaa acatgtcaca aacccttttc
    12781 attattccaa tagaaaggat aaagaatgca aaaaaagatt agcatcatca tcactctatt
    12841 ttttatttgt atacttgctt catggtttat tcagcgtcaa gctgctctat atgacgtacc
    12901 tgtcatcgag atcgaaagag tgagaataga agaggatcaa caattgatta caggaagatt
    12961 gatgaatacg gaccaaaaag gagaagtgat ttctttaacg gctccttatc aaaaaaatca
    13021 aatcgaaaca gcaaatataa caacaagaca aatctatctt gtccaaatgc atggagatga
    13081 atggcaacta gtagcaaaaa aaaatgatgg ctggcttttt ttctttacaa gtgtcttcat
    13141 tggcaccatg ttgcttattg gtggaaaaca gggcgtattt gctttaggaa gtctcatcat
    13201 caacatcgtt ttacttttac ttttgttgct cctctttacc aaaacagaag gtatttctct
    13261 cttaaatata gcaatcttat ttgtcgttat agggataatc gttagtatat tggcgttaga
    13321 cggatggaat agaagcagta taatcaaaat ttcggctgca gttacaagtg tttttttagc
    13381 attttttatt tgtcttttga caatgaatca ttggaaagat caaggactgc gctatgaaga
    13441 actgaattat ctgacacgac cgtatcgttc tgtttttctt tccagcgtgc tgattgggac
    13501 agctggaggg acactcgata ccgtgatcac agtcattgcg acattagaag aattgaccaa
    13561 gcaacaaccg aaaatatcag cgaaacagtt atggctttca ggaaggcaag tgggccgaga
    13621 tgtgattggt tcgatggcta atatcctttt attcgtctat atcagcggag cgattccatc
    13681 gcttctgtta tatttaggaa atcaatggtc tttcaaagaa acggtagaac gacatttatc
    13741 attagaactt ttacgcgtca ttgctggcag cttaggaata gtattatcaa tccccatcgc
    13801 ggtcctcttt tttctcgctg taaggaggtt aaaaaaatga atgtacttat tatacttgtt
    13861 gggatttttg caatcagtgt gctatttgtc ggtggtacgc aaggtatgta tattctttta
    13921 ggattattca ttaatttagg aatctttttc ctattattat tcggctatca tcagaagtgg
    13981 ccgatattgg tattgtcgat tatagggttc ctattgatcg ctgtggttat cttatttttt
    14041 atcaatggtt ataatctgaa aatgcgagcc gcttttgcca gtatactgat ctttttgttt
    14101 tgtttcctac tattgattcc tatcactgat tttttagcga tccaaggctt tacttcgata
    14161 gaactagaag aactatctgg cttagataag acgttagcaa ttgattttag actacttacg
    14221 aggtcgttgc ttctgatcag tcttagcgga gctgttttag atgcgagtgt agcgatttct
    14281 agtggaacat tcgaagtata tcaggcaaat ccgcaaatgt cttttaacca attgcgccat
    14341 gctagctttg ccattgctaa aaaaatattg gcatcaacag tgatgacgct tctttttgcg
    14401 tttatgggga gttctttagc gttgattctt tggtttattg acttagacat ttcttttcag
    14461 caaataatca atgaaaaatc atttgtcttg gaatatacga tggctattct taccacactg
    14521 gccgcactac ttgtcctgcc cttaacttgc gtgactacag catatctctt tacaaaaaag
    14581 aaagaacatc tcaagatgga gtaaaagtta caacttaagt cctatgacat ttttactgaa
    14641 tcagtgcata atatggatgt aaggaaaagc ttgcaaacaa ttttgcttaa ggaggcaatt
    14701 tccatgaaag aaagagaacg tattttagac ttagtgaaaa aaggaatcct ttcgactgaa
    14761 gaaggcttag atttattaga aagcatggca actgaaaaag acgaaaaaca aatcaaaaaa
    14821 gaagcagaca aggtaactgc tagtcataaa gaaaaagatc aggcaagtca attgatcgat
    14881 gaacttgaaa acggtgaaga aaaaatttct gagccagttg atccaaaaga aaaagaaaga
    14941 caagatcaag aaaacttaga aaagatctta gatgaactag caactgaagc gaataaaact
    15001 tcggcgcgtc tagacgaagt aaatgctcaa ttcgctgaca ataaggcagc acgtaatgag
    15061 aaacaggaag cattgatgca gctgaataca aaagaagaat taggcgagtt gacagaagaa
    15121 gaattagcac agcgtcaaac gttagaagca gaaatcaaag agttagaagc aaccggcgat
    15181 acactattag aagaacaatt gaagctggaa gcagaattaa aagatatccg caagaatcaa
    15241 tggtctgaga aaaaagaaac atttacggat aagtttgaat tgccagatga ttggaaagat
    15301 caagcgacag atacgctgaa tcaagtaggc gaaaaaatgt cagaagctgg atcacagtta
    15361 ggcaaattct tgaagaaaac attccaaact gtttcagaaa cagtaaatga taacatggaa
    15421 tggaaagatg tcagcttacg cgtccctgga attgcgacaa cgaaatttga acacgaattt
    15481 tattatgaag ctcctgcagc aagtatcctt gatatcaagg cagcaaacgg aaacgtgacg
    15541 ttaaaaacgt gggacagtga tgatgtgaaa gtggaagcca agatcaaact ttacggaaaa
    15601 atgggtgctg aaccatttga agcattctct gaacggagcc agatcgaggt caatgaagat
    15661 catatctcct tccaaattcc aaataagcgt gtgcgtgcag accttgtttt ctacttgcct
    15721 aaacgagtat acgaccatgc agctatcaaa cttctaaatg gcaacatcat gattgagaca
    15781 ttggaagcta aagatattta tacaaaatct acgaatggga acatcatcgt gaaccaatta
    15841 actgcaacga tgctggaagt agaaggtgta aacggcaata tcgatattcg aaacgggaac
    15901 atcttagatt ctattataga aacagtaaac ggtacagtga catttggtgc cacaccagaa
    15961 aacctttctg tgtctttagt aaatggtgat gtacgtctta cgattaaaga agataatttg
    16021 aaaaaagtag aagcaagttc agtgaacggg aatgtcaaag ttgctttacc agatagcatc
    16081 ggtttggaag gacacgctaa aacaagtctt ggaagcatta acagccgtct gtccaattac
    16141 gaagtagttc gtgagaaaaa agaacggaca aaccaaatgt tgcaattccg tcgtgtttca
    16201 gatgatgaga tcgcacaagt gcagctttca acgacaacag gaagtatcta tttaaaagat
    16261 acagataaat aaagaggttg tgaaagagat gttcagcctt gagcaataag aagcgatttt
    16321 ttaaaatagc ttcccctatt ttaaaaaaat gtgccttatt gccgataggc tatctcttga
    16381 acaccgatta agaagaaggt tgtcacaacg attttcttca tttaaaatag tagaacagag
    16441 gtgagacatg atgaaaaaaa agttgacaaa atccaataaa aatgttgttt tgacaggtac
    16501 tttagcaggg attggggaat atatcgggat tgatcccact gttatccgtg tgctttatgt
    16561 attcttaagc ttagttgctt ttggaagtcc aatcatttta tacattttat tagctttgat
    16621 tatcccatct gcgcgttctg cacgaacaaa ctatggacat aacaatgcat attatgaaaa
    16681 aaacaattat cgtgaacaaa caaaaaaacg caaagaagcg gaaaaaatcg atgatgacga
    16741 atggagtgac ttttaatgtc gtactttcag cgtattttgg ttaatacgtt aacattcata
    16801 tcgttggctg ttctttttcc tgcgatggtc catgtgagca gtatttggac ggccgtcctt
    16861 gccagcttcg tattatctgt gttgaacatg tttgtcaaac cgattttgac gatcctgtcc
    16921 ctgcccttta cattagtcac attgggattg tttacgtttg ttatcaatgc agcgattctt
    16981 aaaatgactt ccttttttgt aggagcagaa cattttagtt tttcttcatt tggtgcagcg
    17041 ttattcgtag ctatcttgat gtcacttgtc aatgtaattg ttagtgaaca taacagcaga
    17101 aaataaaaaa agctgtgccg agatctcggc gcagcttttt tgtttagaat aaagaatgcg
    17161 ttttctatta cattggtaat taaataaaaa cgtttttttt aattggtagt acttttggct
    17221 agacaatgat aaaatgatag agaacactct aatagaaatg aggtagcatg aatgtcagaa
    17281 gttgtaaaag ttagccaatt agtaaaaaaa ttatctttgg aaatcgtcac aggcgacgag
    17341 aaaagtttag accgcgtcat cgtgactggg gacatctcac gcccaggact agagttgacc
    17401 ggttatttta attattattc ccataatcgt ttacagctat ttggcagtaa agaaatcagt
    17461 tttgcggaac ggatgatccc agaagagcgt ttgatcatta tgagaagatt atgtagtgaa
    17521 gatatgcccg catttattat ttcaagagga ttgccggctc cggaagaaat gatccaagca
    17581 gccaatgaaa atgggatagc tgtgctgcgt tcgcctatct caacgtcccg gctgctaggt
    17641 gaattatcta gttatttaga tggacgctta gcccctcgaa caagtgtcca cggtgtgtta
    17701 gtcgatgtct acggattagg tgtactaatt caaggggaca gtgggatagg gaaaagtgaa
    17761 acggcgttgg aactgattaa gcgcggacat cgattgatcg cagacgatcg agtagatgtc
    17821 tatcagcaag atgaactgac ggtaatcgga gaacctccta aaatcctgga acatctgatt
    17881 gagattcgag ggatcggtat catagatgta atgaatcttt tcggtgcgag tgcggtacga
    17941 ggctctatgc aagtccagtt agctgtttat ctagaagcat gggcgaaaga taagaaatac
    18001 gaccgtctgg gctctgaaga cacgaccgtt gaaatcgcgg aagtgggcat tccacaaata
    18061 aaaatccctg tcaaaacagg acgaaacgtt gcaatcatca ttgaagtagc cgcaatgaat
    18121 ttccgcgcac gtacaatggg ctttgacgca acgaaaacat ttgaagaaag attaagtcgc
    18181 ttgattgaag aaaactcagg caatgactag caaggagtga caatatgtta gcacaaatca
    18241 atcgagttgc ttttgagctt gtaggaattc ctatctactg gtatgcattg attatcgtat
    18301 caggaatcat tattgccatg tggctcagca gcagagaagc tgttcgggta ggattaaaag
    18361 cagatgacgt gacagatttt atgttgtggg gattgccgat ttccattatt ggtgcccgct
    18421 tgtattatgt tttattcgat cttccccaat atatagctga tccaatccag atattcaata
    18481 tccgttcagg aggattagcg atttacgggg gattgattgc aggtgcaatc acactgtact
    18541 tttttaccaa atatcatttt atttctttgt ggaccttttt agatatcgct gcaccaagcg
    18601 tattattggc gcaggcaatc ggacgatggg gaaatttcat gaaccacgaa gcgtatggtc
    18661 cagacacgac acgaagtttc ttagaaagtc tgcatttacc gcaattcatc attgataaca
    18721 tgtatatcga aggaatctat cgacaaccaa cctttcttta tgaatcactt tggagtttga
    18781 ttggatttat tctgcttttg gttttgcgga agaaaccaca tcttttgaaa aaaggagaag
    18841 tccttttatg ttatctaatg tggtatagtt tcggacgttt ctttatcgaa gggttacgca
    18901 cagacagcct ttacttttta ggtgtgatcc gcatttctca attattgtct gctgttttat
    18961 ttgtcggcac attgattctg tttatttggc gtagaaaaaa aggaagttta ccggattatg
    19021 accgctcatt aggaaaaaat caacaaatta tttgattttc agagcgttaa aaatgaaaaa
    19081 aatttcagga gtggtaaaat gaattataga gtagcggttt taggaccagg ctcttggggg
    19141 actgctttag cacaagtcct cgctgaaaac ggacatgacg ttcggatttg gggacatcgt
    19201 gcttcacaag tagaagaaat caacacccaa cacaccaatc aacgttattt accagatcat
    19261 catctacccg attccatccg agcattcacc gatatggaag atgcagtaaa agatgcagat
    19321 gcggtactat tcgttatccc gacgaaagcg atacgttctg ttgcaaaaga actagttgcc
    19381 aaattgaata cgaagccagt gatcatccac gcaagtaagg gattagaaca gggaacgcat
    19441 aaaagaatct ctgaaatctt gttagaggaa atcccgacag aaaaaagaaa agctgttgct
    19501 gttctttctg ggccaagcca tgcggaagaa gtagcaaagc atgacattac gacgatcaca
    19561 gcggcaagca caaatgtaaa agcagcaaaa tatgtacaag agctgttcat gaaccattat
    19621 tttcgaatct ataccaaccc tgatgtgatt ggtgtagaga tgggagcagc tttgaaaaat
    19681 attattgcca ttggagctgg tgctattcac ggcttagggt ttggcgataa tgcaaaagcg
    19741 gcaatcatga cgcgcggatt agctgagatc agccgtttag gtgtagcaat gggtgccaac
    19801 ccgctgacct ttattggctt aagcggagta ggtgatctag tcgttacttg cacaagtgtt
    19861 cattccagaa actggcgcgc aggcaacttg ttaggacaag gtcagcctct agaagaggtg
    19921 ctagccaata tgggaatggt tgttgaaggt gtgaatacta ctcaagcagc gatggaacta
    19981 gcccaaatga tggaaatcga aatgcccatc actcaaacaa tctatgaagt gctgtatgaa
    20041 caaaaagaaa tcaaaacagc cgcaaaagaa atcatgttac gtgatgggaa aaaagaaaat
    20101 gaattctcat taacaatttt ttgaaggagc gaatgtatat gaaagtaaaa aaagcagtta
    20161 ttccagcagc aggattagga acaagatttt taccagcaac aaaggcgatg gcaaaggaaa
    20221 tgttgccaat cgtggacaaa ccaacgatcc aattcatcgt tgaagaagcg ttgaaatcag
    20281 gaatcgaaga catcttgatc gttacaggaa aagctaaacg accaatcgaa gatcactttg
    20341 attcaaatat cgaattagaa acaaacctaa gtgaaaaagg aaaaaccgaa ttattgaaat
    20401 tagtagaaga aacgacagat gtcaatttgc atttcatccg tcaatctcat ccaaaggggt
    20461 taggacacgc cgttcttcaa gcaagagcct ttattggaaa tgaaccgttt gtcgttatgc
    20521 taggcgatga tatcatggaa gacgaagtac cattgacaca gcaattgatc gatgactatg
    20581 agcgtacaca cgcttctacg attgccgtta tgcaagttcc tcacgatgaa acttcaaaat
    20641 acggaatcat caacccaggg gaagtactgg aagatgggtt atacaatgtc aaaaactttg
    20701 ttgaaaaacc agatccaagc aaagcaccaa gtgatttagc tattattggg cgttacttat
    20761 tgactccaga aatctttgat gtattatcag aacaacaacc aggcgctgga aatgagatcc
    20821 aactaactga cgcaatcgat acgttgaata aaacacaacg cgtatttgcc cgtaaattca
    20881 caggtaaacg ttatgacgtt ggtgacaaat ttggttttat gaaaacaagt attgaatatg
    20941 gtctgacaca tccagaagta ggggcacctt tgcgtgaata catcatgtct ttaggtaaaa
    21001 cattagaagc agaaggaagc aagatcaatc ataatccaaa aggaataaca gaaatcaaag
    21061 aagaaaagaa aaaataatct ttttttctaa cgagcttcag ctgctaattg aataaaaagt
    21121 agttgaagct cgtttttatt tgtttaaaaa acacgaaaat gctatcctta tagaaaagag
    21181 agacaagaag ggagtttgat catgtcagga ggagaaattg caggattgat cgcagcaatc
    21241 gcctttgcga tacttgtcgt tttcatcgtt cgcgtattgt tgcaagtttc caaaacttta
    21301 gaaaaagtag accagactgt cgcagaagca aatacgacaa ttgagatcgt cacacaagac
    21361 gtagatcttt tatctagaca agtagaaggc ttgctagtca aaagtaatga gctgctcttg
    21421 gatatcaatg gaaaagtcgc aacgatcgat ccattgttca cagcagttgc tgatttaagt
    21481 gaaagtgtat cggaacttaa tcattctagt aaaaacatcg tgacgaaagt cggcggaatc
    21541 ggaaaaacga cagctaaagc gactgttgcc ggaaaagtcg gtggaacagc gatgaaattt
    21601 ttaaaaacaa aaaacatact gaaacgacag gaggaaaata agaatggcta aaaaaggtgg
    21661 atttttatta ggtgcagtag ttggaggtac agccgcagca atcgccgcat tattgttagc
    21721 acccaaatct ggtaaagaac ttcgggatga attggctgct caagcagatg atttgatgga
    21781 catggcttca gattacacag atatggcaaa agaaaaatca tctgagttaa caggtattgc
    21841 aaaagaaaaa gcgcaagatc tttctcaaca agcaggggat ctagcaggca atgttaagca
    21901 gaaggtaagt gaatcagcag aggaagcagg aagcgaatca gatgatatct tgttaaacct
    21961 caaagaacaa tcagctgatt tatctaatcg tttcaaaaaa acagcagaag atctgaaaaa
    22021 gccagcagac gaattaggta gtattgctaa agatacttca gaagatatca tgatcgatgt
    22081 aaaagatgct gcagataaag caggagagac ggtcaatgaa ggaatgtcag aagcaaaacc
    22141 agttgcagat gacacaaaag aaatgttgaa aatggcaaaa gaagatgcaa aagaagatgc
    22201 aaaagaagct aaaaaagaaa tgaaagatac aatgacagat tcgactacca atcactaaga
    22261 ttactcattt ctagaataaa aaaggtgaga gcggaccagc tctcaccttt tttattttca
    22321 ttactctaaa acaagtaatt cttttggtgt agtcgtgaat ggcacacaac catcacttgt
    22381 cacatacaca caatcttcga tacgtacccc tactttttca ggaatataga ttcctggttc
    22441 aagagagaag cacatccctt cttcaatcac taagtcgttt ccttctacaa gagaagggaa
    22501 ttcgtggacg gttgttccga ttccgtgacc taaacggtga ttgaaatatt cgccgtagcc
    22561 atagctgttg atcacgtttc gtgcgatttg atcaagttca cctgctgtca cacctgggcg
    22621 aactgcctct tgtgcggcaa gctgtgcttc aagagtgatg ttatagattt tttcttggaa
    22681 ttcagttggt ttttgataag caactgtacg agtagcatca ctgcaatagc cattccaaat
    22741 aacgccaaga tcgaataaca ctagttcatt tggtgaaacc ttcgtgcttc ctggtgtacc
    22801 atgagggctt gcagcatttg ctcctgcaag gactaatgtg tcgaaagaca tttgtgaaac
    22861 accttgtttt tttaattggt attcgatttc tgcgataatt gcttgttcag ttacgccttc
    22921 ttttactgtt ttgaagccaa tttcaaaggc aacatcggcc catttaccag cttcgatcag
    22981 tttgtctttt tcttctaccg ttttgatcag ttgcagacgc tggataatag aagttagatc
    23041 ggtgtaagaa tctgtacctg tcaagatatc agagatagca tcgaagcgat cgacagtcag
    23101 agcattcttt tcaataccta cattaccagg ttgcccatag cgtgcgcgaa gctcttttcc
    23161 gatgatctcc caaggatttt cgctgtctaa gtagccacgt acatcgtacg cccagctgct
    23221 gttttgagca tcttcaactt ccagagcagg agtgaaaagg aaaggatctt gttccagagg
    23281 gataaaaaga gctagtacac gctcgtgagg atcactttca tatccggaaa agtaagcgat
    23341 gtggccaggg tcgctgatat aagccaattc taattggtgt tgtgccatcc attgacgtag
    23401 ttcattgatt tttacgttat tcatttggca acctactttc taaattaatt ttgtattcaa
    23461 taattgtacc actgattgat taaaagacca acgttcttaa aactgaaaaa agtaaaaatt
    23521 ttcatgaaaa cagagataaa acggttgcaa ttgttgagat tatttgatat cctattttag
    23581 aaatgtaaga cgtattttca gaaaacatat aaaatatgaa taggagaaca caaatggaaa
    23641 agcaaacaat cactatctat gatgtagcga gagaggcaaa tgtttcgatg gctactgttt
    23701 cacgtgtcgt aaatggcaat ccaaacgtca aaccagcaac aagaaaaaaa gtcttggaag
    23761 ttatcgatcg cttggattat cgtccaaatg cagtcgcacg tggcttggca agtaagaaaa
    23821 caacaacagt tggggtaatc attcctgatg tcagcaatat gttctttgcc tctttagcac
    23881 gtggtatcga cgatgtggca acaatgtaca aatacaatat catcttagca aactcagatg
    23941 gcaacgatca aaaagaagtc aatgtattga ataatttatt ggctaagcaa gtggacggcg
    24001 tgatctttat gggtcaccat atcacagacg aaatccgtgg agaattttca cgttcaaaaa
    24061 cgcctgttgt actagctggt tccattgatc cagatgaaca agtaggtagc gtaaacattg
    24121 attatgtatc agcaacaaaa gatgcagtaa ataaattagc aaaaagcggc aataaaaaaa
    24181 tcgcttttgt cagcggtgcg ctgattgatc ctatcaatgg tcaaaaccgt ctaaaaggct
    24241 ataaagaagc attaagcgaa aacaatctac catatagcga aggattgatt tttgaggcac
    24301 aatacaactt taaagatggt ctgtctctag ttgaccggat ccataatagc ggtgcaacag
    24361 ctgtctatgt ttcagacgat gaattagcca ttggtatctt ggatggttta ttagaccgcg
    24421 gcgtaaaagt accagaagaa ttcgaaatca tcacaagcaa caattcttta ctgacagaag
    24481 tagctcgtcc tcgtttgaca agtatcacac aaccattata cgatttagga gcggtatcca
    24541 tgcgcctatt gacgaaaatg atgaataaag aagaagtcga agaaaaaacg attatcttgc
    24601 cttatggaat cgaagaaaaa ggatcaacta aataataaaa gatcaatcat ttaaaggttg
    24661 ttcccaaagt ggtcaacttc tggaacaacc tttatacgag aaaaggggtt atgacaaaat
    24721 tttgtcataa cccctttttt tgtgacttta aaaaaaagag agaatggcgg aaacaaacct
    24781 tacgtccatc gtatacgaca caatctgtgc gtagatgcta cattttgttc actactatca
    24841 aaattacttt aaaatgaaaa cgtgataaaa aagaaagtag aaaagtagaa aagtaactct
    24901 aaaaaatcca aaaaaatcca ggctcgattg cgtacttatc ttaaaggaga aacaatccat
    24961 catacataac ccgaaaggag acttctattt gcctaagaaa agacgaaaga ccatagtcat
    25021 cattttgacc attcttacta taggaatcgg aggaaaattt tacatggaca aaagagaagc
    25081 gcaaaaacag caagatttac tcgcagtaga aaaacagtcc gtcaaagttc tgaaaaatac
    25141 ctttgcggat atcaaagaag tgaaaatcga acaatttgag aaaaacgaca tgacaggaat
    25201 ctatgaagca ttgataacga tgaccaatac agaaggaaaa gccgtttatt ttgattatag
    25261 ctttacaaaa gaaagcaatg agatagatgg ctatggtgtt gaaaatgaag aagtacaaaa
    25321 agaagggatt acggttgatg agattatagt tatctataca gatgggagtg aggaaaaagt
    25381 atgacaatta ctgataagca gtataaagga ataagtaata aagtatattg gctagatcca
    25441 aaacatcctc aatatagtaa aagttacaaa gaaggcgcca ttaaaaactt tggagaaaca
    25501 aaattccaaa tcctaaaaat caaaaactcc ttcgacggca tgcaggcgat ggctgtagcg
    25561 ccaatcaaga acggtaaagt ggatatttct caagtagtga ttgcttttgc aggaacgaac
    25621 ttaagcgatt ggaaagattt ggaaacggat gcaagaagtg ttatgaatct ctatgggaat
    25681 agaccaggag caagtttttc tgaaaaagca acaacaaaca agattttatc cgttagtgga
    25741 ttgaaaacag cggggcaaat caattcagcg attgcatttg ctaatgaagt aaaaaaggaa
    25801 tatggagaag ctgctatttc tactaccggc cattcattag gtggattctt agcattatat
    25861 gtagcagcag agaaacaatg gaaaaatgtc ggcttcaacg ggccggaccc gtatgatctc
    25921 ttatcaccag aagcaaaaaa atgggtggaa gaaaatcccg gtatgctcac caattaccga
    25981 aatcacgccg attttatcgg taattttggt ggtaatggca caggtgctga agttcggatc
    26041 agtatggaaa cagcatactt gaatctgctt gcttcccaca gtttaacctc ttggaagttt
    26101 gatgaaaatg gaaagctgat tattcctgaa aatgaaaaca atgttaaagc tcgaaaacaa
    26161 cagaaagaaa accaagcgac ccagttgttt tcctatcagt tgcaagaact gaacaacata
    26221 cgtaaaaaac tacgattaag tggcggccgg ctgacagtta atgaacaaat ttacttagat
    26281 gacacacaag ctaggttagt ggtggaaaag ttatcggtaa aaatgaaaag cgctatggaa
    26341 gaagttatcc gcatcaacca aagaggaatt tttgagctag agaaaaaatg gcaagaaggc
    26401 ttgcggcaag cacgtgttgt cgccccttcg ttgactgaac aggaaatcat agaagcatta
    26461 gctagtgtgg gcgccacaaa agagaactta gtcgattctg cgaaagaagt ctatctgcta
    26521 cgaatcaata aggcaagacg tatgggggag gcctttgata cattggcgaa ggagatccaa
    26581 gacaaaatca atgaaatcgt ggcacgagat cgagaattag cacagcaatt caattaaagg
    26641 agaagtagat gaaactagaa gaattggaaa gagattatcg aagtgaacga agacaattag
    26701 aagctcaaga agatgaattg atccacttta agaatcaagg attacgattg atggagcaag
    26761 aggagcagcg actgcatcat gtattaaaga acttagcttt agataatgag cctctgtttc
    26821 aagcaagacg aagttattcg aattatcagg agcattatca acaagcccta caagtagaac
    26881 gacgaaaact ctatcagcag caagacgaac tagaacgttc ctatcgtcaa aaaatcagac
    26941 aaataactat ggagaaatca tcttatgaat gaatttttaa tgcaattact aaaagaatta
    27001 gagaaaaatc tacatcgatc aaatgtacgt tcagttggta tggggatatc tcagcaaact
    27061 tgggcagaaa aacgattgac agatcaaaac caccaaatga ctgcagaaga agctactcaa
    27121 gaattttcta accgacatgc acacttaaaa gaatcagtaa aagggcaatt tgcagaaaaa
    27181 ctaaccgaat tattccaaag acaagaaaag aaattaaaac agtttcgtta gtaaagttat
    27241 atagaaaaat tttgtgaaaa tggtttttca catttttaca taaatttgtc ttaatatcgt
    27301 agatgtaagc ttttgaacac catttattcg gaaaaaggga gctgtgacaa gatttttgtc
    27361 gcagctccct ttaattctga ttaatctatt agatcaatca tctttatcgt ctgattcttt
    27421 ggtctctgga ttcgctctag cataagctga agcggtgttc cagtaatctg tatagttttc
    27481 atcagtaccg ccaacgccga atttaaaggc gcttttcttc ggaccatttt ttgcccaaag
    27541 tgattccact gtttttcctg gcgtttggat agatttttta ttgacagtaa cttttccagc
    27601 tgtttgtcct gtgaacccag atactttttt cttcatcaca tcggatgata agtcaaattt
    27661 ctcatcagtg ccgaaaatct cagggtttgc ttggtaagct tgattgatta gattggcaag
    27721 ataattagcc gaacgtattc ttgcttggct gtccattcca gtattgtcat cgtgtcctgc
    27781 ccaactactg atagtgatag atggagttga gacgatcagc catgaatctc ggtattcatt
    27841 ggtagaacca gtttttccga cccaatctgc atttcctaga tttccgttta agcttgagat
    27901 gacatctttg aatggtgtag tgattttttc attgatcaca ctacgcatca tgtcattcat
    27961 gatcgatgcc gttgcttcgg aataaatacg gacagaatta ctttcatgtt tataaatcac
    28021 attacctgca ttatctgtga tggaatcaat gatatagcct tcttcgtaga ctccaccatt
    28081 tgctaaggcc tggaatccat ttgtctgttg aagcgtcgtt acatctactg tccctaaagg
    28141 agccgattca acgccccaat tatcatttgc tgggtagttc atcttcgcca agtagtgctc
    28201 gtaagcgtat tgtttcgatc caccggaatt caacacatct tgatataagt gataagctgg
    28261 gatattgttg gaccattcca gtgactcacg gacggtttgg aaggtgttcg acccttcatt
    28321 ggtcgcattg acgattttct caccagcatt ttttccttct tgccaagtcg ttgcataatc
    28381 tgatacacgg gattctgatc cgacaagtcc catatcgatt gcaggaccgt aaacaagaac
    28441 cggtttgatg gatgaaccag cttgacgttc tgtatcaaag gcgtggttat tttgattctg
    28501 gctgtaattc cgaccaccca cgaagccata gatacgtccg gttctgttat ccatcaatac
    28561 atttccagtc tccacttggc taccagcacc atcatctaac atgtagccat aattttctac
    28621 gccggtttgc aatgcagcat agatatcttt atcaatcgtc gaatggatcg tatatccttt
    28681 gttttggatc gtttgctgtg ctttttgata ataagcttca ctgaccgatg aatctgacat
    28741 atcagcatta tctttttctg ccaattgttg tgcaataatc cttgttgctt cgttcatcac
    28801 ggtataatac aagaattctc tgtcagtctg ttccgcgatt tgttgtggga gaaagtcttt
    28861 tgtaagatca taggctttcg cttcttcgta ttgttctttc gtaatttgtc cttcacggta
    28921 catactgaat aaaacaaaat cttttctggc aagaccggca gaaagatctt cttttagcgc
    28981 gcctgtattc gtgtatggac tatacgtgat agggctttga ggcaaaccag cgatataagc
    29041 agcttgcggc agagtcacat cctttgcatc tacaccaaag attcctctag cagcttcctg
    29101 gactccagca atattttgcc ccttattatt ccgaccaaat ggtgagacat tcaaatacgt
    29161 agtaatgatc tcatcttttg aaaagtgttt ttctacttgt gcagaaagaa cgatctcgtt
    29221 tgctttacgt ttgaatgttg tttcatcggt taggatctgt tgtttgacta attgctgtgt
    29281 caaagtggat cctccagacg agccgatgcc agtcgcttct gaaactagtg ctcgtaaaac
    29341 agctttaggg acataacctt ggtgtttatc gaagtattca tcttctgtac tgataatcgc
    29401 ggttttcaat aaaggcgaaa tcttatcaga tgaaatagtc gtccgcatca gatctgtctg
    29461 gatttttgat atctctgtat tatctgcata aacaatcttt gacgtttccg taatgtttcc
    29521 tagttctgtc tgcagttctt ttttagtcgg caattgtgtg tcttcgacaa gataggcaaa
    29581 gtagccagca cctattccga tacctagagc tgcgaacaac aaaagaagaa cagtaataaa
    29641 aacagtcaat gattgaaaca ctctaaaaat aatcttagga acaaaccatt tttctttttt
    29701 tcttctattc tgtttttttc gagtattttt gcgtggcaaa agggtcacct caactaatgg
    29761 ttttatttcg ctaattatag caaataatag gacaaaaaaa cagacaaggc tgtttttgac
    29821 aggaatttct ttttcgaatg agataaaacg tgaggaaatg atctttttta tgaaagagtt
    29881 cttaagcttt tctttaggga aagtttcagt tactatggag aacagggcaa agaaaaacaa
    29941 actattttct ttgtacatca tcttatcaat atacaggaat tgttcgaaac aattgccttt
    30001 caaggaggaa tccatccatg ttattaggct cacacgtcag catgagcgga aagaaaatgc
    30061 tgttaggcgc ggcagaagaa gcagccagtt acggatcttc gacctttatg atctatacag
    30121 gcgctcctca aaatactaga agaaaagcta tcgaagagat gaatattgat gccggaaaag
    30181 catttatggc agaaaacgga ctaacaaata tcgtcgttca tgcgccttat atcattaatt
    30241 tgggaaatac gatcaaacca gaaatgtttc catttgctgt acaatttctg agagaagaga
    30301 ttgtccgtgc ggaagcttta ggtgctactc aaatcaccct tcacccaggc gctcatgtag
    30361 gagcaggggc agaagctggg attgctagaa ttattgaggg gttgaatgaa gttttgacaa
    30421 aagaacagac ggcacagatc gctttggaga cgatggcagg gaaaggtacg gaaatcggtc
    30481 gaacatttga ggaattagcg caaatcatcg atggagtaaa attgaatgaa aaattatccg
    30541 ttacttttga tacatgtcat acgaatgatg ccggatataa tataaaagaa gatttttcag
    30601 gtgtaatgga agagtttgat aaggtcatcg gattagatcg gcttaaagta ctgcatatca
    30661 atgattctaa aaatcctcaa ggttctcata aagatcggca tgccaatatc ggttttggaa
    30721 caattggatt tgacacattg aacaaaatcg tccatgatcc aatgtttgac aacatttcga
    30781 aaatattaga aaccccatat gtcggtaaag ataaaaagaa agcttacgca ccatatggaa
    30841 aagaaatttc catgttcaaa gcgcaagcat tcgatcccga agtgttccct gagttattag
    30901 cagaagaagt cacactttaa gttttctacc tgacagcaac aaaaaaggat tgggcagtct
    30961 gccttgtcct tttttgttta agaaacaaag gagtgctttt tgcattcgtt ttcgccatgc
    31021 tccttttgcc ccctcttttt aaattcagac aaacagggta tactgataga aaagtaaaaa
    31081 acgaaaagtt tcacaaacaa gtagcaaaac gtgattgaaa ggacgaaaag atgctgaaca
    31141 ttttaaaccc cttgatcgac caactaaaaa agaaacatac atactttatt cttggcatag
    31201 ccgtattatt tacaattatt cggttgtatt tatatagtaa agcaatctat ggaacagata
    31261 tgtcggcgac ctatgatgat cagctgctga ttcactatgc tcaaaatatt ttggatggta
    31321 aatggctagg ggagtacacg actacgacac tttcaaaagg gatttcctac agcttgtttt
    31381 tagtacttgc acataaactg catctttctt atgcagtttt attcggcatg ttcagtattc
    31441 ttgccagtat attggttgca ctagcgttta aaccaatcgt gaagaacaag tatcttcttt
    31501 taagtatcta tttttatttt ttgttttctc cgattagttt tacacatgaa tattccactc
    31561 gaacatatcg taatgctctc gtgatcccga ctgttgagat cattatcgct tgtttactag
    31621 ctatttatta ccgcaaatat aattccagca aaaaattgct gccgtggttt ttagggctag
    31681 ctgtttcttt tcctttcttt tggttcattc gcgaagattc catctggctt cttcctttta
    31741 ctgtagtcgc gttaggcatc agtttcgttc agatcttgct aggacaagac ttttctttca
    31801 aagaagcaaa gaagttaaaa gaacgaccat ttctcctttc gaaacaagaa tggctgaaac
    31861 tttcattgtt tttactccct ctagtcggtt tctccatcgt ctatcagtgg atcgaatata
    31921 aaaacgagac aacatatggt attgcagcca tcaatgaccg ttcgagtggc gaatttggac
    31981 gtttgatgaa acagctgatc cgaatagatg acgaaacaaa cttaaataaa gaaaacagtg
    32041 agatatgggt ctcgcatgct gcattaaata aagctttaga cgcatctcct acatttcata
    32101 ctgtttctac tcgtattgac gaattgtata cgactcatgc gtggacccaa ggcggaaaag
    32161 taaaagaatt accaggagat atcatttttt gggcattgcg agatgtggta agcgaatctg
    32221 gttattacca aaacaatgca aaagaaacca atgatttttg gaaaaaagtc aatcaagaat
    32281 tagaagaagc ctatcaaaag ggaactatca aaaagaaaaa agaattctat ctgatgggat
    32341 caggggatgg aaagacgatg aatgatctgc caatcgtatt tgattttctg aaatcaggat
    32401 atgcttatgc atggcgatac aaagatttcc atcaaggggg gaattatagt tttgggacgc
    32461 aagaacaagt cgaacaggca caagaattat tgaatcttcc actaatggat aattggatcg
    32521 atagcagtga tccgagaaca cctgatttcc agttgacaaa aacagcaaaa gtcgcgaatg
    32581 tcatgataaa aatttaccaa gttctggcca ttcccgtgct gattgcttca atagcaggga
    32641 tattacttat gatactagga accgtatttg caaaagctga tcgtgcctat tatagttcct
    32701 ctttgattgt agtcatcgga ttaatactga cacaattggt ttttcttttc ggtgtctcgt
    32761 ggttttgttc ttatgcgcca gaaaaaaagg attatttttt aagtgtctac actggcgcag
    32821 gcgtgccatt aacgcaattc atcgcagtaa caagcatgct agtttttagt aaattgaatc
    32881 tgaaaaaagc tttatcttcc aaataaaaag ggaactgtga caaaagtctt gtcgcagttc
    32941 ctttttccga ataaacggtg ctcaaaagct tgcatctgcg gtaataagct caaccaaacg
    33001 taaaatatga ggaactattt ttgtttggct gttcttatta cttgatgcag ggcagctttt
    33061 tcacaacctc tgatacacgg tgttccagaa gtaacttctt cggaaataag ccgaaatttc
    33121 acaaaaattt gaaaagcaat tttcttaaat tccttcttat ttcttgaagc tgcccacttc
    33181 tgtcacaacc tcctttgtgt aaaagaatca gtttctattc gatttcttct atcgtttctt
    33241 gcaaacgctg ttcatatttt ttgtttcctt tatataaatc accaatcgtc catgccaaca
    33301 ggagaaggac aagaacaatg attacatagg cgatttgatc agccaatgct agttgagctg
    33361 aggtggcttg ctcgccgaag aaactttcga tttgacctgg taatcctcgt aagttcaagt
    33421 aagtcagact aatcacagag aaccagccaa gaagttttac aacaaatgaa tttttgaatc
    33481 ggctccccat ctccgcttgg ctattggtca tcatcagtaa aggaatcatc gagaatggca
    33541 atgcaaaagc cagaaaaact tgggattcat tcatcaagtt attcaaagcg gtatgttctt
    33601 cgatcgttcc ttttgtactt gtaaacaaaa cacaaatcaa tacaggaatc acagaaagca
    33661 atcgtgtgac tagtcttctt agccaaatcg ggatacgcat atggatgaat ccttccatga
    33721 tgacttgacc ggtcaacgta ccagtaatag tagagttctg gccagaagca agaagtgcta
    33781 cagcaaataa agtagacaag ataccagatt ttgctacagc aatcaagata ccattgctca
    33841 tagctgatgg atcagataaa gcttcataca gaccaaaaaa ggaaggatct tggacagaac
    33901 cggttttgaa tacagcgaca cccatgatca atagcagtgc attgactaaa aaagccattg
    33961 acaactggat attagagtcc caagtagaaa agcgtaccgc ttgtgctaca tcttcttcgt
    34021 cttggtgatc gatcttccga gtttgagaaa ctgctgaatg aagatataag ttatgcggca
    34081 tgactgttgc accaataatc cctaacgctc cagtcagcgg agtttcacca cctatgacag
    34141 gtgagtctga gaatgtatga ctgttaggga taaagccagc aaataaactg tgccaatcag
    34201 ggttagacaa gccaacttga tagacgaaaa cgaataaaat gacgaaaatc aagcagacaa
    34261 ccaaagcttc gattttacga aacccgactt ttgtcagcaa taaaaggacg aaaacatcta
    34321 acacagtgat aaatacggca attaccaatg gaatatcaaa aagtaagtag agggcgattg
    34381 ctgcaccaat gacttctgcg atgtctgttg ccataatggc taattcagtc aagatccata
    34441 aaatgacacc caatgtctta cttgtccgtg ctcggattgc ttgggccaaa tccatttggg
    34501 tcacgattcc taattttgct gccatatact gtaaaagcat agcaattaga ctagacatca
    34561 aaataactga catcaataaa tattggaaat tttgtccacc agtgatcgaa gtggaccagt
    34621 tacctggatc catataacca actgctacta atgcacctgg tccagagtaa gcaagaagtg
    34681 ttttaaaaaa actttttccc tttggtacat ccactgttcc atttacttca gctaaagata
    34741 aaccatttgt atgttcaata agtcgatgct tatgaaattg tttgttggat tgattattca
    34801 agaaaaaacc acctttccta tttatctacg attacattct acacctcaga aagaaaaaat
    34861 taaagaaaaa gattcggtat gcctaatttt ttttcgtggc gtgtcttgct ggttaatgaa
    34921 agaaattttg ttcttctcta aaaaaaccac tattttttgc atgaaactaa agaatacgcc
    34981 tttctttttt caataaactt tagtaaaata aatcattgag agcaattcgg aaatagaaag
    35041 gagagattta tatggtatca acaggtattg tcgtacttat tgctattatt gctttgctaa
    35101 tcggcgcagt aggtggcttt ttcctagcgc gtaaatatat gaaagactat ttagaaaaaa
    35161 atcctcccgt taatgaggac atgttgcgat caatgatgat gtcaatgggg caaaaaccat
    35221 ctgagaagaa aattcgccag atgatgcagc aaatgaagaa ccaagggaaa aaataggttc
    35281 tgacccaaag actttttgcg ggctgatttt ttcagtccgt tttttatttc gtaatttgtt
    35341 agactattca gactattcag caaaaaagac aaggacagac aatcctatgc tcttgataaa
    35401 gacaaaggag gagtaaaatg tcgattttta gaaaattagg ttggtttttt cgtcaggaaa
    35461 agaaacatta tttaattggg attttctccc tattcgcagt ggccttggta cagttagttc
    35521 ctccaaaagt gattgggatc atcattgatg agatcgccga taagaattta tcaataaaga
    35581 tcatttcttg gtggatctta ctattgatcc ttgcagcttt cttacaatat ctttttcgtt
    35641 atatctggcg gacgaatatt tggggaagtg cagctcggtt ggagaaagaa cttcggcagc
    35701 agctattcaa acattttaca gaaatggaca atctctttta ccaaaaatat cggactggag
    35761 atttgatggc tcatgcaacg aatgatttga atgcaatcca gaatgtagca ggagctggaa
    35821 tcttgacctt tgcagattca gtgattacgg gcggaacaac gatcattgcg atgattttgt
    35881 ttattgattg gcgcttaaca ctgattgcgc tgattcctct gcctttgcta gccgttactt
    35941 cacgagtgct ggggtcaaaa ctccacgatg cttttcgtga ttcgcaagaa gctttttcta
    36001 gtatcaatga taagacacaa gaaagtatca ctgggatcaa agtcattaaa acatttggac
    36061 aagaaaaaga agatctcgcg gattttgaag aaaagattga agatgcaatt attaaaaaca
    36121 aacgagtcaa ttttttagac tccttatttg atccattcat taccttgatt atcggtctgt
    36181 cttatgttgc aacaattatt ttaggtggaa agtatgtctt ggaaggcacg atctcgattg
    36241 ggcagatggt ctcatttatt agttatatcg gtatgcttgt ttggccgatg tttgcgattg
    36301 gccgattgtt caacgtattg gaaagaggaa atgcttctta tgatcgcgtt aatgaacttt
    36361 tgcatgaaaa gacgcatatc gtggaacaac tgggtgcagt gcagaccccg gcaaaaggcg
    36421 agctgaatgt agctatttcc tcttttaact atccgaaaga agaatcacca gcattagaac
    36481 aaatcaaatt tgcgatccaa gaaggagaaa cattaggtat tgttgggaaa actggtgcgg
    36541 gaaaaacgac aatcatcaaa ttactgatgc gtgaatacga tgattatcaa gggaaaatcc
    36601 aatttggcgg acgttcgatc aaagaatatt cattgaatgc tttattagga tcaatcggtt
    36661 atgtgcctca ggatcacttc ctgttttcga tgaccattcg agataatatc cgtttttcta
    36721 atccaaaact ttcagaagaa gaagtagagc atgcggcttc tttagcattt atcaacaatg
    36781 aaatcaagga attgccaaaa ggttatgata ccttagttgg agaacgtgga gtctctttat
    36841 ctggcggaca gaaacaaagg atttcgattg ctcgagcatt gatcaaaaat cctgaattgc
    36901 tgatcttaga tgatgcactt tctgcagtag atgccaaaac agaagaagct atcttgcata
    36961 atttaaaaga aataagaaaa gagaaaacaa ccatcattgc agctcaccgt ttaagcagcg
    37021 tgatgcatgc aaaagaaatc attgttgtcg atcaagggaa aatcattgaa cgaggaaccc
    37081 accacgagct gcttgcatta ggtggctggt atgaacgaat gtgggaaaaa cagcaattag
    37141 aagcgaagat agaaggaggc gaggcctgat ggatgaaaat tatcaatcgg aatggacaaa
    37201 atcgattcca cttaaagaac agaagaagat catcaaacga ctgatgaagt tcgccaaacc
    37261 ttttagaaga acgttcatcg ttgctatctt atttgcgttt gccctgtctg tgatcaatgt
    37321 cctattgcca aggatcatcc aaacttttat ggatgatcat ctggctaaac agtcagctac
    37381 gacacaagtt attttgtttt ttgctggtgt gtacttgttt ggagtcatag tcaaaagtat
    37441 catttggttt ttccaatggt atttgtattc catggcttca ttgaagacct atcagtatgt
    37501 tcgggtaaga ttatttgaaa agctgcatac actaggtatg cgttattttg accagacacc
    37561 ggcaggatcg accgtttctc gagtgacgaa tgacacagaa acgctatttg aattttggta
    37621 tgtctttttg atggtattga ctgggatctt tgcagtcgtt tcttctttcg ttgccatgtt
    37681 tcaaatcaat ggagaaattg ccttgtggac tttggtgttc ttgccgattt taggaatcgt
    37741 catctggtat taccagaaat tcagttctcg tatttaccga aatatgcggg aaaaattaag
    37801 tcagctgaac acgaaattga atgaatcgat ttccggcatg cgtattatcc agcagtttcg
    37861 ccaagaagct cgtttagcta aagaatttga acaagtgaac aacgagtatt tagacacgcg
    37921 ctatgcgatg atcaaaacga attcgattct gttaagtccg atcatcaatt ttctctatgc
    37981 attggcgatt gcgttggcgt tgactttgtt tgggatcgat gcgttgcatt ctcccgtaga
    38041 agttggactg atctatgcat ttacgaccta tgtccaggga ttttttaatc caatgtctca
    38101 aatgatggac tttttgagca cctttacaga tgggatggtt gccggtagtc gtattttgaa
    38161 aatcatggat acagaagaat atgcaccgca acaaaatcct ggagcagatc aagcgattac
    38221 ttcaggtaag atcgagtttc gcaatgtaag cttttcttat gatggagagc acaatgtatt
    38281 gaacaatatc tcttttgtcg ctaatccggg tgagaccgtt gcattagtgg ggcacaccgg
    38341 aagcggaaaa agctcgatca tcaacgtatt gatgcggttt tacgaatttt atgaaggcca
    38401 aatcttgatt gatgatcatg acattcgaga atatccaatg gaagagttac gtaagaaaat
    38461 gggattggtc ttgcaagatg ccttcttgtt ttatggagat attgcaggaa atatccggat
    38521 gatgaatcca gctatcacag acgaacagat tcgccatgca gctgagtttg ttcaagcaaa
    38581 caagttcatc gatgaattac caaaaggata tcactcaaaa gtgatcgaac acggtgccag
    38641 ctattctagt ggacaacgac agctgatcac ttttgcgcga acaatcgtga cagatcctaa
    38701 aatactagta ttggatgaag caacagcaaa tatcgatact gaaaccgaag gattgatcca
    38761 agaaggattg gcaaaaatgc gacaaggacg gacaacgatt gcgattgccc atcggctgtc
    38821 cacgattcgg gatgcagaat tgattttagt tttagacaaa ggtcatatag tagagcgtgg
    38881 gaatcatgaa acacttctag cgcaaaatgg tttgtatgca gatatgtaca aactgcaaag
    38941 cagtggtgtg taaaaagagg ttgtgacagt agcatagtag cattttgtcc taagcgctag
    39001 agtgaaaata aaacagagct tcccagattc ttcatctgtg agcgttagtg gcgtagtcac
    39061 ccgatttaaa aaagacgacg acagctagtc aaaagtgcct aatagccact aagaaagcgt
    39121 tgacaaaagc gtttgctttc gataatataa agaaaacgat acaacttgga tagtgattgc
    39181 ctgatgcaag ctaaacctga tgagtctccc atggttccat ggacggcttt ttgggttttt
    39241 ctttttgttt tgaatacagc cctatatatc atggaaagga gcaaaacatg ctgattgaga
    39301 aagtactgaa taacaacgtc gtaataacca gggatgaaag aaatcaggaa atgatcgtga
    39361 tgggaaaagg tttggcattc aaaaagaaag tgggtgaccc gatttttgac tcatgcatcg
    39421 acaaaaaatt tcagttgaca aatgacgggc tttcacaaca gttccaagaa ttggcacaag
    39481 cgattcctct tgagtactta gaaatttctt gtgaaatcat tgaatataca aaagaggctc
    39541 tacaagtcca gttgaatgat tctgtgtata ttgcattgac ggatcatttg tatacggcta
    39601 tcgaacgtca caaaatggga atatttgtac caaatgtatt gctgtatgat atcaaacaac
    39661 tatttcctaa agagtatgcc atcgggaaaa aaacagtgaa gaaaatctcg gataaatacc
    39721 acatcaagtt atcagaagat gaagccggat ttatcgcatt gcatttagtc aatgcacaag
    39781 gcattcaaag ccaacaaaac aatacctacc tgtttactat aacaatacag gatattctaa
    39841 atatcgtccg ctattactat aagattacat ttgatgaaga ttcagtccat ttttttcgat
    39901 tcgtcacaca cttacgtttt tttctgacac gcgtcctaga tggagaaaaa tcagaagtgg
    39961 gagaagtttc tgaggaattg tttcaggtta ttcaaaaaaa atataaggat acgtttggtt
    40021 gcgttgagaa aatagcagac tttttagccg agacgttcaa ctaccagatg tccacggacg
    40081 aaaaaatgta tttaacgatc catactgcgc gtttagtgca tgagaatcgt tgtaaataaa
    40141 taaaaaaagg aggataaatt aacaagaacg tatgaaataa gggtagtgac attcagttgg
    40201 ctaaaccttc cactaatata ttggagggaa tagaaatggg aaaataccaa gaattagcga
    40261 gaaaaatcgt agaaaatgtc ggtgggaagg aaaatatcaa tggtttgaca cattgtatca
    40321 caaggcttcg tttcaaatta aaaaacgaag aaaaagcaaa tgatgagatc ttgaaaaata
    40381 tggacggtat tgtaacggta atgcgagcgg gagggcagta tcaagttgtc atcgggaatc
    40441 atgtgccagt cgtgtttgaa gaggttataa aagcaggaaa ccttactttt gatgaggctg
    40501 tttcaacaga aaaaatgaga ccgtttgata tgcttattga tggaatatcg ggctgtttcc
    40561 aaccattcct tgctatctta gctgctggcg ggatgattcg tggactgaca gcattccttg
    40621 tcttcttagg cgcgtttgac cgcggttctg gcacatttgt tatgtttgat aatatcggtg
    40681 attctgtatt ccaatttatg cctgttatta tcggtttaac agctgcccgt aaatttaaag
    40741 taaatgaatt cgtagggatg ttgcttggcg cagcattaat gaatcctagc ttgtcgctgg
    40801 aagctttgag tggtgcagca gaagcaccac taacgaccat attttctggc actatttttg
    40861 aagcacctat ttatcaaaca gtattcggca ttccctggat tgcgcgtaac tacgcttctt
    40921 ctgtcattcc cattatcttt attgtgttgt tagctagcca aattcagaaa ccaattaaaa
    40981 agttagtacc tgagatgatc gcgaatttct tcgttccatt cttcaccgtt cttattacaa
    41041 tgcctttagg ttttttactc gttggaccag tattcacatt cgcaactgat attttaatgg
    41101 ctggatttga aacactttta gcactttcgc cagttattta tggagcaatc gtaggcttct
    41161 tctggcaaat tctggtgatg tttggtctcc attgggcaat cgtaccaatg ggattgatgc
    41221 aattttctgt gaatggttgg caaaatatta tgacacctgt tgcagtagtg tcttttggac
    41281 aaactgcagc acttaccgca ctctacttta agcttagaaa tccaaaagac aaagcaattg
    41341 caataccagc cattgtttct ggtattgtgg ggattacaga gccagctatt tatgggttta
    41401 cattaccacg taaaaaaata tttattttta cttgtgtcgg tggtgcgtta gggggcgcgt
    41461 atagtgggtt aatgaattta acttcttgga atcaaggtgg actaggcatc tttacaattc
    41521 ccaactatat tagaccagat ggtgatttaa cagatgtgat taatgtattg attgggatcg
    41581 ccattgcgat ggtggtatcc tttgcgctga cttttttctt ttggaaggag gaagcaggtg
    41641 aaacagatga cagacagaaa agatcaggta aagaaattgt aaaaacaccg atacaaggac
    41701 aaatcgctcc actgaaagca gcaaaggatg cagcttttgc acaaggaaca ctaggtcgag
    41761 gaatcttgat ctaccctgaa aaaggagaag tacgtgcccc ttttgacgga acagtcatga
    41821 ccctgttccc cacgaaacat gcaatcggaa tggtttctga aacaggtctg gaattgctga
    41881 ttcatgtcgg attggatact gttcagttgg aagggaaata ttttgaaagc ttggtgcagc
    41941 aaggagaaag agtgaaacaa ggcgatctgt tgctccgctt cgacaaaaag aaaatcgaaa
    42001 aggaaggata cagtttagaa acacctgtaa tcgtcaccaa ttacatggat tatttggata
    42061 ttttggaaaa tcaaggggag acggtcgggc cagacgatgc acttatcacc gcactgacct
    42121 gaacggttag gtgaaagaat ggaatagact taactattct ttttagtcca cttctttatt
    42181 ttcaaaattg aaaggctctt tcatgatggc tgagctgata gggcgtttat caaatttttg
    42241 tcctacagaa attagatgga ctaaattctg ttgataattt tctgcaaaaa cacaactata
    42301 taacacgtct agaagataac aaatcgatgt attgatcgta aaattaccaa tttttgaata
    42361 cagtcgttcg cgtgtcgtaa gtcgcaaagc ggctgtactc attgaggata gcgttgaatc
    42421 accgatactg gtcaacgcta aaattggaac atgattttgt ttcaatattt ctgcggtacg
    42481 aaggatcaca ttgttttcac ccgtataaga aatcagaatc ccgcacatat cactcgtgca
    42541 attgtacgct tcatagaacg attcaccaaa agtggtgaca atcgtgacat ccattttgat
    42601 gcgcttcatt ttcagcatga aatcttgaga aatcaaagta ttcgagttac tggcgaaaat
    42661 cacgattttt tttgcttgaa gcattagttg tttggctttt tgcagttggt catgatgaat
    42721 gagagaaagt gtatcttgaa tcgtcatctg ttctaaagaa gccattttat ttgcgatcgt
    42781 cataataccg tctgtggtgg aaaaaggaag attcgcatct acgtcttgaa aattcccttc
    42841 aagataggct gtttcagcta aaaaagcatt acgaaaactg acccagccat caaaacccat
    42901 tttttttgct acacggatga gtgtggacgg gtggacataa catcgctcag caatctcttg
    42961 gatggtcatt tcgccaagtg ctggagaatc gcttaagaga aactgaatca cttcattttc
    43021 tgaaggagaa aaggagattt ctttgatttt ttcacgtaat aacatgtaga taccttcttc
    43081 tagttttttt acgtaaatta taactttttt gaaaatgatt tgtaaacgga tttatgttat
    43141 atagcttaat aaagtcattt tttgacaaga tatttacaaa aatccagtag aaaacactaa
    43201 cttttgtaaa tgttactgga aagaaacgaa tttctattgt ttgttttgtt tacaaaaaag
    43261 ataataaaag tgtaaaaagc aaaggagtga gaacatggca aaaggaatca aaatcgctac
    43321 gattggtgga ggcagcagtt acacccccga gttgatggaa ggatttatca aaagatatga
    43381 ggaattaccg atacgagaaa tctggctcgt agatgtagaa gaaggaaaag aaaagcttga
    43441 gatcgtcagt cagatgtctc agcgtatgtg ggatgcttct ccgtatgaag tcaagatcta
    43501 tgcaactttg gatcgggaag aagcattgaa agatgcggat tttgttacga ctcagtttcg
    43561 tgtcggtcaa ttagatgcac gaatcaaaga cgagcggatc cctagttatt atgggatgat
    43621 tgggcaagaa acaaatggtg ctggcgggat attcaaagct tttcgtaccg ttccagtggt
    43681 tttggcaatc gttgaagaca tgaagcgttt atgtccaaat gcttggctga tcaatttcgc
    43741 gaacccaagc gggatggtga cagaagcagt tatcagatat ggcaaatggg ataaagtgat
    43801 cggattatgc aatgtgccag taatggcgac gatgacagaa ccagcaatgc ttggcaagaa
    43861 aaaagaagag ctgatctaca agtttgccgg tctaaatcac ttccattggc acaaagtagc
    43921 agataataaa ggaaatgacc gcacagcaga tttgattgat cgtttatacg atgaagacaa
    43981 tggattgccg aaaaatatct ttgacatccc gtttttcaaa gaacaattaa aacaaatgaa
    44041 catgatccct tgtggctacc accgctatta ctaccgtgaa gaagaaatgt tggaacatgc
    44101 tttagaagaa tatcaaacga ttggtacaag agcgcaacaa gtgaaagaaa cagaagcaga
    44161 gctgtttgaa ttatacaaag atccagaatt ggatcataaa cctgaacaat tgcaaaaacg
    44221 aggtggtgct tattattcag atgctgcctg tgaaacgatt gcttcgatct atggaaataa
    44281 agaaacacag atcgtggtgt ctacaaagaa tgatggagct gttcctgatc tgccggcaga
    44341 ttgtgtagta gaagtcactg cctatgttgg cgcacaaggc gcacgaaatg tagcgtttgg
    44401 ttcccttcct gctgctgaaa gaggctggtt gcaagtaatg aagaatatgg aattgctgac
    44461 gatcgaagca gccgtgactg gtgattatgg aacagcttta caagcgttta cgatcaatcc
    44521 gcttatacga tcaggaaaga cagcaaaacg gatcatggat gagttgttta ttgcacatca
    44581 gcagtattta ccgcaattca aggaaacaat cagccggtta aaagcagaag gaatcgaagt
    44641 ccaagatgaa ctggcaagag aattgtcaag caatacacat gtaatggagg aagtatgatg
    44701 ggattcagaa aagatttttt atggggcggt gctacagcag ccaatcaatg cgagggtggt
    44761 tatgatgaag gcggacgtgg gttagcgaac gtagatgttg tgccaatcgg agaagaccgt
    44821 tttcctgtca ttactggaaa aaagaaaatg tttgaatttg ataaagatca tttttatcca
    44881 gcaaaaattg cgatcgatat gtatcatcat tataaggaag atattgcttt gtttgcagaa
    44941 atggggttca agacttatcg gatgtccatt gcttggagtc gtatttttcc aatgggcgat
    45001 gaaaatgagc caaatgaatc tggtttgaaa ttttatgagg atgtctttaa agaatgtcaa
    45061 aagtacggga tcgagccgct tgtgacgatt acacattttg attgtccgat gcatttgatc
    45121 aaagaatatg gtgcgtggcg ttctagagaa ctcgttggtt tttatgaaaa tctgtgccga
    45181 gtcatcttca atcgctataa aggacttgtc aaatattggt tgacattcaa tgagatcaat
    45241 atgatccttc atgcaccatt catgggcgca gggctgtatt ttgaagaagg agaaaatgaa
    45301 gaacaaatca aatatcaagc ggcacatcat gagttggttg caagtgccat cgcaacgaag
    45361 attgctcatg aagtagatcc ggagaacaaa gtaggctgta tgctggcagc aggagcatat
    45421 tatccataca cttgcaatcc tgaagatgtt tgggcttcta gaaaatcaga tcgagaaaat
    45481 tatttcttca ttgatgtcca gtcacgagga gaatatcccg cttatgcatt gaaagaaatg
    45541 gaacgaaatg gcattcagat caaaatggaa cctggggatg ccgcattgct gaaagaacat
    45601 actgttgatt ttatctcctt ttcttattat tcttctcgag tttcgactac tgacaacgaa
    45661 ctcttggaac agactgcagg aaatatcttt gcttctgtca aaaatccata tctggaagca
    45721 agtgaatggg gttggcaaat tgatccatta ggcttgagaa taacgatgaa tgatatttat
    45781 gatcgttatc aaaaaccact atttattgta gaaaacggct taggtgcagt cgatacgccc
    45841 gatgagaatg gttatgtgga agatgactat cgaatcgact atctggcagc acatatccag
    45901 gcaatgaaag atacagtaga attagatgga gtcgatctat taggctatac gacttgggga
    45961 tgtattgatt tagtatcagc tggtacaggt gagatgaaga aaaggtacgg attcatttat
    46021 gtcgatcgtg acaacgaagg aaatggcaca ttagcccgtt cgaagaagaa atcattcaac
    46081 tggtataaaa aagtaattga ttcaaatgga gaaaatcttt cgaatgattg atcaatgatt
    46141 tgtaaaagtc tattgttttt cagcggattt ttcgagtata ataaagctat tcgagaaacg
    46201 caagcagaac aatagacttt ttttcgcatt ggctgtaaag tatgcttact tgattaagta
    46261 aaggagaatc tacatatgta tgatgtaatc gttattggcg caggtcctgc tgggatgact
    46321 gctgctttat atgcttcacg ttcaaactta tccgtattga tgatcgaaca aggcgcccct
    46381 ggcggccaaa tgaacaatac ggcagaaatc gaaaactatc ctggtttcga ttcaatcatg
    46441 ggtcctgatc tagcttataa gatgtatgaa ggtgtttcaa gatttgggac agaaaatgct
    46501 tatggaatcg tgcaagatat caaggatcac ggcagccaca aagaagttat ttgtgaagat
    46561 aaaacttacg aaggaaaaac agtcattatc gcaacaggct gtatccaccg taaattaggc
    46621 gtacctggcg aggaagaatt tgctggacgt ggcgtttctt actgtgcagt ttgtgatggt
    46681 gcgtttttcc gtaacaaacg tctagtagtg atcggaggag gagactcagc agtagaagaa
    46741 gccatctatt tgacacaatt tgcttctgaa gtagtcatcg tccaccgtag agatgaatta
    46801 cgtgcacaaa agatcatcca agaccgtgca tttgcgaatg aaaaaatttc ctttatgtgg
    46861 gatacagtcg ttgacgaaat cgttgggaat gaaatggtag tgacaggtgt gaaagcacgt
    46921 aatgtcaaaa ccggcaatga gtttgatttg gcagcagacg gagtattcat ctatgttgga
    46981 ctggatccat taactgcacc atttagagaa gcagggttga cgaacgaagc tggctggatt
    47041 ccaacagaca acgaaatgaa gacgaatata ccaggcgttt ttgccatcgg agatgttcgt
    47101 gaaaaagatt tgcgacaaat cactactgct gttggtgatg gtgggatcgc tggacaacaa
    47161 gtgtataaat acttggaatc tttagaagaa acaactgcat aagtttaaaa agagtggaag
    47221 aacggtttca attgttcttt tactcttttt tttcgcgtga aatctactga atccgattta
    47281 tgcgaatact tgcaaccgtg cttgataaaa gaatcctttc ttgatttaag cgttttttag
    47341 acctcgtact ttcatatcta ataagtgaat gctatactta ttaagaacca tatttcagaa
    47401 agaggtgtta ttttcatgtc ttgggaacaa gtgtatgaac aatgggtaca tgaagaaaat
    47461 ttagaagaaa acttaaaaaa acaattaatt gatctgggtg aagatcctga aaaacttgaa
    47521 gatgcttttt atgcaccgtt ggaattcggt actgcaggca tgcggggaat cttaggacct
    47581 gggatcaatc gaatgaacat ctatacggta agacaagcaa cagaaggact tgcacgtttc
    47641 atggatacac aaggtgaaga aacaaaacgc cgaggtgtcg ctatcgctta tgactcacgc
    47701 catcaatcac cagaatttgc catggaagca gccaaaacat tagcacatca caatatccct
    47761 tcttatgtat tcgaaagttt acgtccaaca ccagagcttt cttttgcagt ccgtcatttg
    47821 aagacgtttg cgggaatcat ggtaactgca tcccacaatc cagcagctta caacggatat
    47881 aaagtctacg gagaagatgg gggacaaatg cctcctgcag acgcagatgc attgacgaaa
    47941 tatgtccgtg aagtcagcaa tccgttaaaa gttgaagtat tatctgacga cgaagctgaa
    48001 catagcggat tgatcacgat catcggagaa gaagtggatg ccgcttatct agaagaaatc
    48061 aaagcagtaa cgattgatca tgaattggtg gaaacaatgg gtaaagattt gaaacttgtg
    48121 tacacaccac ttcacggaac aggaaaaatg ttgggcgaac gtgcgttgaa acaagctgga
    48181 ttcgaacaat tcgtactagt tccagaacaa gctgtcgcag acccggattt cactacagtc
    48241 aaatcaccga atccagaaga acactctgct ttcgagtatg cgatgcgact tggcgagaaa
    48301 gaaggcgctg acttactgat tgcaacagat cctgatgcag accgtttagg cgcagccgtt
    48361 cgtttgccaa atggctccta tgaagtattg acagggaacc aaatcggagc cctgtttgct
    48421 caatatattt tggaagcaca ccaatcgcga ggcactttac ctgaaaatgc agcggtattg
    48481 aaatcaatcg tttctagcga attgcctaca gcaattgcgg aacactatgg ggctaccatg
    48541 ttcaatgtat tgacaggatt caaattcatc gctgaaaaaa ttcaacaatt tgaagaagat
    48601 cattcccata cttttatgtt cggattcgaa gaaagttacg gttatttagt taaacctttc
    48661 gttcgcgaca aagacgcgat tcaagcattg ctcttattag cagaagtagc agcttactat
    48721 aaaaaacaag gcaaaacgtt gtatgacggc ttgcaaacga tttttgaaac atatggctac
    48781 tacgcagaaa aaacgatttc tgtgacaatg agcggacaag aaggttctgc aaaaatctct
    48841 gctttgatgg aaaaattccg tgaagaagca ccgacagaat ttgccggagc aaaagtcatc
    48901 caaacagaag acttcaaaga gttgacgaga acagaccgtg aaggaaacgt agaaaaacta
    48961 acgacaccgc catctgacgt attgaagtat acgctggaag aaaatggctg gatcgctatc
    49021 cgtccttcag gaactgagcc gaaaatcaaa ttttatatcg gtgtaaaagg aaactcttca
    49081 gaagacgcag ctgaaaaagt agccgcttat gaagcgatta tcaaaaaaat gacagaagaa
    49141 taaaaaaact tgagactgat ggaaaaagtg gtaaacttta gaagtcagtc ttttttcaag
    49201 ttggaggtga atggattgcc agacacgcaa aaaacaaaag tagagaaagt cagccaacta
    49261 ttcaaaatgt tgagtgaccc cactcgtctc aaaattctgc tgtatctgaa agacggggaa
    49321 caaaatgtga cagcaatcac ccaagcagta gaaatggaac aatctgctgt atcgcatcaa
    49381 ctgcgtttat taagagaaaa ccatgtcgtc aagtcccatc gtgagggaaa agcgattttg
    49441 tatagtcttg atgattctca cgtactggat attttgaacc agacgctcaa acatgtggaa
    49501 catcaataac gataggtgca aatagagaca aactggactg tatcaacgaa tcttcttcgc
    49561 tgacacagtc cagttttttt aagaaaaaga caagaaaaac tgttagtctg tttcttcggt
    49621 ggtttcagtt ccataataac tatgatcttc taggtctaaa gcattcaaaa taagtgaagc
    49681 tgtttcttcg atagataaag aagcgacatt gattactacg cagcccaatt tttcataaag
    49741 atcattcgca aaatcgagtt cagctcgtat tttttcgata tcggaataag cagtatcagg
    49801 atttaatccg taagagcgca tccgttcttt acggatattg tttaaaatat ctgggttatt
    49861 cgtcagtccc acgatttttt taggatcgat ctcccaaagc tgtttgggaa tatgtgcttg
    49921 tgggatcaaa ggtagattgg caacctttaa atttttgtta gctaaaaaca agctcaaagg
    49981 cgttttggaa gttctggata cgcctagcaa aacgacatct gcttctagaa acccacgagg
    50041 atctttcccg tcatcgtatt ttacagcaaa ttccattgct ttgatccgtt tgaaatagtt
    50101 ctcattcaat aaatgaaggg cgccaggttg ccgaatgggc ttgataccag ttaagcgctc
    50161 gatttctgat atcggcggag tcatcacatc aaaactaaat aattgatgtt cttcacaaaa
    50221 agaacgcgtc atctcgatca attcttgatt gatcaatgtg tgcaggacaa gggctttttc
    50281 ttttagtgca tcttgcagtg cctgcatcaa tgttttctca tctgtcacaa atgttctgcg
    50341 gaataaattg aactcaacgg taggatattg ggccatagtg gcttgcgcta attttgtcgc
    50401 agtttctcca gcagagtcag agatgacaaa aaaagtaacg atttctgtag aatcggaaga
    50461 catggataaa acctcacttg catttttttt atgtttatta taccatactc tagaatgtgt
    50521 acttcgtaat cattttgatt tggaggaata agtcatgaaa aaacagacat tgattgaaca
    50581 atcactagaa acattgaaaa ataacggttt taaatatact aaaaaaagag aagcattgtt
    50641 aacttattta gtgaagcgca atcgctacgt atccgctaaa gaagtttttg actatatgaa
    50701 tcaggaattc aaaggagtaa gttacgatac gatttatcga aatctccatg attttgcaga
    50761 aatcgattta ctggaagaaa ccgatttaaa tggagagatg aagtttcgtt ttcattgctg
    50821 tcaaggggaa atcggccatc accatcactt tatctgtacg gtgtgcggaa caacgaaaga
    50881 aatccatatg tgtccaatga attatttcga agaacagctc ggtggatgta cgatcgaagg
    50941 gcatagattc gagattttcg gaagatgtga aaattgtcaa taaggattta aataaaataa
    51001 catttgataa ttttaaaaaa aagcaagatt tccttgacgg tcaaaacagc attagatata
    51061 atatttacag gacagtcttg ttttttgaga tatatttcaa taacaattac ggttactttt
    51121 taagctcgga gggagggaat taacatgtca aaaacagtcg ttcgcaaaaa cgaatcactt
    51181 gacgatgctc ttcgtcgctt caaacgttcc gtgtcaaaag cgggtacttt acaagaatct
    51241 cgtaaacgtg aattctacga aaaaccaagt gtaagacgca agaaaaaatc tgaagcagct
    51301 agaaaacgca aaaaattcta gttctgtgat gaattggagt tggtagtgtg tcactactaa
    51361 gtagattaaa cgatgacatg aaaacagcga tgaaagcgaa agataaggaa tctttacaag
    51421 tcatccgaat gatcaagtca tctatacaaa acgagcagat taaagaaggt cacgacttga
    51481 cagaagaaga agaattaacg gtgttgtctc gcgaaatgaa acagcgacgt gattctttgc
    51541 atgagtttga agaagcagga cgtgacgatt tagctgaaaa agtaaaaagt gaaattgtga
    51601 tagtcgaaaa atacatgccg gaacaacttt ccgacgaaga aattcgacaa cttgttcaag
    51661 aagcaatcac acaaactggt gcttcatcaa tgaaagaatt tggcaaagtc atgggtgcga
    51721 tcatgcctaa agtcaaagga aaagcagatg gaaaccaagt aaatgccatt gtgaaagaac
    51781 tattacaatc ttaattttat catttaaact gcggacaatc attgtccgca gtttttttgt
    51841 gcgcgtaaaa aagagaacaa aaaaatagct agacgaaaga ataggattct ttcatctagc
    51901 tggttttttc ctgtttaata tttcttatgt taaattgtgt ttgatttggt tattcttctg
    51961 gtagttcatt tgcttcttgt ttataccctg ataggcgata ggcgtaataa aacagtaggc
    52021 tgccagcgta accaagtaac gttgggacca tccagccaag tcctaatgca gcaaaaggaa
    52081 cgtgatgatg ataaaattcg agcatgcttg ctacaactct ttgttgactc actaaagcag
    52141 gcgaatttgc cagcatatcc aatacggcag gaacagcagc aaacaacatc gttacttgat
    52201 agacaaatgg tgtcttttgg aaaaattttg ctgttaagga aagcaagatc aacgcaagcg
    52261 acaatggata caaaagcatc aatactggta aagaccattg gatgatattg tctaaaccag
    52321 catttgcaac gacaaaagag acgaaagtcg ttaaccgcag ccatgtcata taactgactt
    52381 tagggaacag tttatggaaa tcttgcgcaa aagaaacaac gagtcccata gcggtagtga
    52441 agacacctaa tgtgaccatc actcctaaga agctagcgcc gaagttacct aaataaaaat
    52501 tagtgatctg agaaagtgca gttccgccat tttctgataa agacatctta ttcaaactca
    52561 tcgcaccgag aagaacaaga ccaaaataga tcatgacttc tagcgcaacg ctcaggctac
    52621 cagcttttgc tgttaattct gtgacttttt tatctttgaa accaaggtca cggactgcat
    52681 ggacaaaagt gacacttaag gcaagcaagg ctactgcatc aaccgtgtta taaccttcta
    52741 ggacaccatt tgttaaagcg tttgtttggt aagtatctgc agcagattga tttagatttc
    52801 ccattgggtg gaataaagaa acgacaaaaa tgattgctaa caatgcaaga aacaaggagt
    52861 ttagatactt tccgacgtat ttgaccaacc gtgtgggatg gacagtaagg aaataagcaa
    52921 gtaaaaagaa aagagcagag aataaaaaca tacctaatga attatatttt tcaggcaaaa
    52981 atggtttagc agccatttca aaagcagtag cagctgtccg tggtgtaccg aaaaatggtc
    53041 cgatcgtcaa atgaacaagg attaagaaca aggcagcata ccattttccg acaggtttag
    53101 ctaagtcata cagaccatca ctttttgtca ctactacagc taagatagct agtaatggga
    53161 aaagagcgcc cgagatggca aatcctacgc cagcactgac ccagtttgcg ccagccattt
    53221 gacctaagtg gacaggaaag attagattac ctgacccgaa gaacatcccg aagataagtg
    53281 aactgaccat caatagttgt ttccatgaat aagtttttgt ttcttccata aatttttcct
    53341 ccaataatta tcattttgat tgacgatata aacgttgcag caattagtaa tgccactaat
    53401 atcagattcc atgaaaacca ccaccttaaa atataaaaaa agcccttttc cacttgggaa
    53461 aagggctcta gattctagaa cggtaccacc ttttttcgct taaaaaagct tcttcattca
    53521 cggacgcttt ttgataaagt tatccgctag cctgataatg gaggcagcca caatgatcta
    53581 cgttttcgac attgactcgg aaatgatgtt cgtctattcg atttattgtc atttctcact
    53641 tacatgactc actgggaata aatcgttgaa tagcctactg ttttcctcga cgctttgctg
    53701 tatgtttatt tgttgacgta ataatacacc tgtttttttt gaaatgcaag aatattttaa
    53761 ctattttgtt ttcttttttt gaaacaagaa aaatacctag agaatacctg ctgaatgaaa
    53821 cggaatattt tgttctccac tttcatataa cttacattct cagcttcttt ttatcaaaac
    53881 gagaccttta gcgaatggaa acggctattt tttaacgttt cttggtacgt atggttaaac
    53941 gactctttta caaccttttc ttatttgcta tatagtttct tctgagtatg gtaaaatagg
    54001 aaagaatgaa tcgaaaaaaa ggggatgtct atttttgacg gaagagtcta gttctttaga
    54061 gattagattg acagctgctg atgatgtcag catgctttta ggtgcacacg acaagcatat
    54121 aaaactgatc gaggaaacaa cggaaacaac catccataca cgtggagaaa tcattcagat
    54181 cattggtgag caatcccaga tttccttggc tgcctcagtc attcggacat tacaggaatt
    54241 gatcaaacga ggaatccacg taagtacgcc agatgttgtg acggcattga agatggggca
    54301 aaaaggtaca ttagattatt ttgttgagat gtatgaggaa gagatcgtca aagaccgtaa
    54361 tggaaaacct atacgggtaa aaaacagcgg tcaaaagaaa tacgttgaat cggtagccaa
    54421 acatgacatc gtatttggtg tagggccagc cggaacaggg aaaacgtttc ttgccgtagt
    54481 attagcaatt gctgccctaa aaaaaggcga agtgcaaaaa atcattttga cgcggcccgc
    54541 tgtggaggca ggggaaaacc taggctttct acccggggat ctgaaagaaa aagtggatcc
    54601 ttatctgcgg cctgtttatg atgctttata ccaaattttt ggattggatc atacgaaccg
    54661 attgatggaa cgaggcgtga tcgaaatcgc acctttagct tacatgcggg ggcggacatt
    54721 ggatgatgca ttcgttatct tggacgaagc acaaaacacg acagtcgctc agatgaaaat
    54781 gttcttgacc cgtctcggtt atcaatcaaa aatgattgtc aatggggata caagtcagat
    54841 agacttgcct cgtgggacga caagtggtct tgttcatgca gaacgaacat taaagcaaat
    54901 caaaaaaatc gattttgtta attttgaagc aagtgacgtt gttcggcacc ctgtagttgc
    54961 cgaaatcatc aaagcttatg aaaaggcgga tcttcatcaa gaataagctt tgcttaggag
    55021 gataagcaca tgttgaataa aacactgcag aaactacaaa aaaaactcgg aaaggcagca
    55081 ttgcctttcc ttctgttctt gttttttatc attgtctgcg gcgttacatt tagtagtgtc
    55141 aaacaaaagg ccaatgattt cagagaaggc caagtagcag aagagagtat ccgtgcgaat
    55201 aaaacgattg agaacacgga agaaaccgaa caaagaagaa aactggcagc agaagcagtg
    55261 actccagaat atacttatca aaaagatctg gcagatgacc agaacaatcg gatcaagcaa
    55321 ttattcgaat tgatcgataa gacgaatgat accatcaaca aatcttataa tgacaaggta
    55381 gataaggcga aggaagatga aaatatcccg aaacctacta cagaagagcg gattgctaca
    55441 ctgaagaaaa attttgaaaa cgtgaatgca gaaaacgttg cgttttacca aaaactgccg
    55501 aacaattttt attcgacgat atttgaaatg actgaaacgg aaattcacac ggttagggat
    55561 gaaagtttga agctcattga cgaacagatg agtaaacaag ttcgtgaaag cgaattggaa
    55621 gcttttaaac aagaagcaga agatcagatt caatatttga atgtcacaac agagcagcaa
    55681 caaatgattc gctacttagt ggatcaaggc attgtagtta atgatgtatt gaatgagaaa
    55741 aagacagaag aattaaaaca atctgcacga gaagctgtac aaccagtgat gatcttccaa
    55801 ggagaaatta ttgttcgcga aggaaatcaa attgatgctt cagcgatgaa aaaattggaa
    55861 ttactaggat tgacgaatca aacgacttct attttcccac tcattgccat ggttttagct
    55921 gttttgcttc aaatcggtgt actgatttat aattcacttc aattccaaaa tgcaggagaa
    55981 agaacaaaat acgtactttt ctacgtgacg gcaatgtcag taagcgtcgt actaatgaaa
    56041 tttttccaac tcttccaaac agaacaagct gcttatattc cgctgtttta ccccgcggct
    56101 tttgctccac ttgttttaag ctttttcttg aatcgaagag cagggatcat ggctggtatt
    56161 tttcaagcag tatccgcact tttcattttt tatgattcga ttggcacgaa ctttctgaca
    56221 gttattttga tgtcctatgt attttctggt ctcatggcaa cgatcgtcag acgcaaacgg
    56281 atctcagaac aagggttatc cgctgctatg tgggtcatta tttttcctgt gatgatggat
    56341 gtcattttga ttatctacca aggaatgagc tttggggatg caacgacttg gttaacgcta
    56401 gtatgcggat tcacaggtgc actgttctca ttcttgctga cgataggtct gcacccctat
    56461 attgaattga tggtcaatga tgatagtgtg atcgtattaa atgaactcag caatcctaat
    56521 catcctttat tgaaacagtt gctggaagaa gcaccaggca cgtatcacca tagcatgatg
    56581 gtagccaatc taagtgctaa tgctgtagca gaaatcggtg gacgttcttt actaactcga
    56641 gtagcttgct attatcatga tatcggcaag atcaaacacg ccagcttttt cgttgagaac
    56701 ttgccttcag gagcggaaaa tccgcacaat ttcttattgc cagaagacag taaacatatt
    56761 atctttggac atgtgacaga tggtgccaaa atattggaag attataatat gccgcaaatg
    56821 gtgatcgata tttgcagaca gcatcatgga accacgctga tgcgttattt ctacgttaag
    56881 gcaaaggaac gcaacccgga agtcacggaa gagcaattcc gttatcctgg accaaaacct
    56941 caaagccgtg aagcaggaat cgtcaatata gctgacagtt gtgaagcggc agtacgagca
    57001 atggaccatc caacgagcga aaaaatcgaa agttttgtcc ataatcttat tgaagagcgt
    57061 atttccgatg gacaattgga cgacagtgga ttgacgttaa aagaaatccg taaagtagaa
    57121 aaatcattga tcagcggttt aagcagtacc ttccattctc ggatcaaata tcctaaaatg
    57181 aaatcggaag ttgagaagat aaaagaagaa caagaagaat agaaagaagc gatgtataat
    57241 ggatattact ttcatggatg aaacaaacca agtctcagaa gagaaaatga aagaaatcga
    57301 cgacttgctg caatttgcag catcatattt agagttgcca gaagaaacag aaatgtctgt
    57361 tactttcatg gacaatgcag cgatccaagt aatcaatcgt gattaccgtg gaaaagatgc
    57421 accgacagac gtcatcagtt ttgccttgga agaagagggc gaagacgaaa tcccagtgat
    57481 ttttgaagat ggagagaatc cattgcctcg tgtactggga gacatcatga tctctactga
    57541 acgtgctgca gagcaagcag aagcttacgg ccattcgtat gatcgggaac ttggcttttt
    57601 agcggttcat ggattcttgc atatcaacgg gtatgaccat atgacaccag aggatgagaa
    57661 agaaatgttt ggtttacaga aagagatctt agatgcctat ggacttaaaa gataaaaacg
    57721 tagagaaaaa caaacatttc ctgatgtccg tggaatttgc cgtccaagga gtcaaaaccg
    57781 tttttgagga agaacgcaac atgaggaaac atgttgcgtt cggaatcctc gctttgttta
    57841 tgggcgtgat tttccagctt gatcggatag aatggttatg gctgctttta gctgtttttc
    57901 tcgtatggat agtagagatc atcaatactg tttttgaaaa tgtcgtggac atgtttacgg
    57961 attttcattt tcatccgatt gggaaaaaaa tcaaagatat ggcagctgga gcagttttag
    58021 tgaccgcttg tttttccgtc atcgttgggt tgattttatt tgtccctaaa atatatcatt
    58081 tgttgtttaa ttaaaaagga gaacgtatat gccagaacat aaatcagggt ttgtcgcaat
    58141 cgtcggccgc ccgaatgtag gaaaatccac attattgaat cgaatcgtgg gtcaaaaaat
    58201 tgccatcatg agtgataagg cgcagacaac tagaaataaa atccaaggag tatatactac
    58261 accagaagct cagttgattt ttattgacac accaggaatc cataaaccaa agcatcgttt
    58321 aggagatttt atggtagaag cagcttacag tgcgttgaaa gaagtggacg cggtcttatt
    58381 tatgatcagc gctgatcaaa aacgcggtcg gggagacgat tttattattg aacgtctaaa
    58441 aaacgtgcat tctcctgttt atctgattat caataaaatc gataaaatcc atccagacga
    58501 gttgttggga atcatcgaag attattcaac gcagatgccg tttgcacaag tgattccaat
    58561 ttctgctaca gaaggaaaca acgtcgaacg tttgatggat gtattagtca gtgaaatgcc
    58621 agagggccca caatattttc cagatgatca agtgactgat catcctgaat acttcatcgt
    58681 ttctgaattg atccgtgaga aagtcttgtt tttaacacga gacgaagtgc ctcattctgt
    58741 cgcagtcgtt gttgattcga tgaagcgaaa cgagaatgat aaaatccata tccaggctac
    58801 gattattgtc gaaagagata gccaaaaagg gatcattatc ggcaaaggcg gaaaaatgct
    58861 gaagcaagta ggaacgaaag cgagaaaaga tatcgaaaat cttttaggag acaaagtctt
    58921 tctagaactt tgggtcaaag ttcaaaaaga ctggcgagac aaaaaagtct atctgcaaga
    58981 cttcggctac cgaaaagacg aatattgata ttctgagctt cttgtaagtt aggtatagaa
    59041 ataaactgga taaaaatccg cgtgttgaga aaagctgcgg aagatcgcaa cataaatgat
    59101 ctggatcggc agaatctgct tttccagatt tattttttag gagggagaat atgagccagc
    59161 ttgcagaatc aaaaggcttg attttatcta gccgtaatta caaagaaaaa gataaattag
    59221 tcaaaatctt tacggaatct tctggcaaaa tgatgtttta tatcaaaggg atccatcggc
    59281 aaaatcagcc cttagctccg gctttgctcc cttttactga agcagtttat atcgggaatt
    59341 ttcgaagtga aggtttgtca tttttaagca gtgtcaaaga tgtccacgcg tttcgacaca
    59401 tccaagaaga catctttttg agcggctatg gcacatattt attgaatcta gtagatgcgg
    59461 caatcgaaga tcatcagtac gacccgcatt tgttccagtt tacgcaacaa gcactgcaac
    59521 tgatggacca aggagatgat gcagaaatca tcacgaatat ttttgaagtc caaatactgc
    59581 aacgcttcgg aattgcacca atctggacac actgcgtcgt atgtggggaa acaaaaggaa
    59641 aatttgacta ttcttccaaa tatggtggtg tgatatgcga aagacactgg tcgatggatg
    59701 atcaccgtta tcatgcagat cctcgagctg tttatttcgt tcggatgttt tcagctattt
    59761 cttatgataa aatcagtgga atccatctga aagaagaaac caaacaagca atccgtgaac
    59821 tcatcgacca gctgtatgat gaatatgtcg gtatccattt gaaaagcaaa aagttcattg
    59881 atcaaatgaa gtcttgggca cacgtattaa agacgtcaga gaaagacatg tctgaaaaag
    59941 atctacctaa aaaagaagaa tagtaaatga aacatacaac aaaaaatcaa aaccatttga
    60001 caaacacagg gagttccgtc tattattaac cgtagatcaa atagatcgtt cactgagagg
    60061 atctattata gaaacaagaa aactgcaaaa tgaatacgta cattgaccaa gatcagtaaa
    60121 aaacacgtgg tttagcgagt tcgggagagt gggagccgga cccaaacgat ttttgaagag
    60181 gcacttgcga gtacgataaa tgaagctgcc gaatctttat tcggaagtag ggtggaaccg
    60241 cgaattattc gtccctatgt ctgtaatcag acatagggat tttttgtcgt tttctttcct
    60301 gtattcttat ttgacagcaa cgctttaaaa ttgaaagggg caaaacagat gagtaaaaaa
    60361 ttgaccgtcc aagatatgat tttaacatta caaaaatttt ggtcatcaaa cggctgcatg
    60421 ctgatgcaag cgtatgacac agaaaaagga gcaggtacga tgagcccata taccttttta
    60481 cgggcaatcg gaccagaacc atggaatgct gcttacgtag agccatctcg ccgaccagct
    60541 gatggacgtt atggcgaaaa cccaaaccgt ttgtatcagc atcatcaatt ccaagtcgtg
    60601 atgaaacctt cacctgagaa tatccaagag ctttatttag aaagcttgcg ccttttagga
    60661 atcgatccac tagaacacga catccgtttt gttgaagaca actgggagaa cccatccatg
    60721 ggctgtgccg gtgtgggttg ggaagtatgg cttgacggaa tggaaatcac acaattcacg
    60781 tacttccaac aagttggtgg actgccttgt aaaccagtaa cttctgagat cacttatgga
    60841 ttagaacgtc ttgcttctta tatccaagaa gttgaaagtg tctatgattt agaatgggct
    60901 gatggcgtga aatatggcga gatcttcaaa caaccagaat atgaacattc taaatattct
    60961 tttgaagtaa gcgaccaaga cttgctacta agcaactttg atcgttttga aaaagaagct
    61021 aaacgctgta tcgatgaaaa tcttgttcat ccggcgtatg attatatctt gaaatgtagc
    61081 catacattca acttattaga cgcccgcggt gcagtatccg taacagagcg tgccggttat
    61141 ctttctcgca tccgcaacat ggctcgtgct gtagccaaaa tctttgtggc agaacgcgaa
    61201 aaattaggat tccctttgtt gaataaaaac acagcaaatc cagaaaacgt gaaggaggct
    61261 gaataagatg gcaaaagact tattacttga aatcgggctg gaagaaatgc ctgctcatgt
    61321 tgtcacacca agcatgaaac aattagaaga aaaaacagca aaatttttag atgaaaacca
    61381 attgacttat gatacgatcg aaacattttc cacaccgcgc cgtttagcaa tcaaagtaac
    61441 aaacattcca gaacgacaag cggacagtga agaagaagtc aaaggaccag ccaaaaaaat
    61501 tgctttggac gcagatggaa actggacgaa agcagcggaa ggatttgtcc gcggacaagg
    61561 tctgacgaca gacgctatca cttttagaga attaaaaggt gtggaatatg tctatgtaac
    61621 gaaatacact catggtaagg aatccaaaga agtattgaca ggtttagcag atgtcattaa
    61681 aagcctgact ttccctgtaa cgatgcattg ggcagaatac gattttgaat atatccgccc
    61741 tattcactgg atcgtggcat tgttagatga cgaagtaatc ccattcgaaa tcttggatgt
    61801 caaaacaggc agagcctctc gaggtcatcg tttcttaggc gaagatgtga catttgcgca
    61861 tgcaaaagaa tatgaagaaa aattgaatga acaattcgtc attgcgtctc cgcaaaaaag
    61921 acaagaaatg atcgttacac aagccaatga attagccgaa aaaaatcatt gggttattga
    61981 tctagacgaa gatttactag aagaagtcaa caatttagtc gaatatccaa ctgtcttttc
    62041 tggcgacttc gaagaaaaat atctttctgt tcctgaagaa gtactagtca cttctatgaa
    62101 agaacatcaa cgttatttcg aggtacggaa tgatcaaggt atgctgcttc ctcattttat
    62161 ttctgctcgt aatggtgatc gggtaaaatt ggaaaatgtg gttcgaggca atcaaaaagt
    62221 attgacggct cgtttagaag atgcggaatt cttttataat gaagacaaga aagcttcaat
    62281 cgaccaatac gttgaaaaac taaaaactgt tactttccat gaaaaaatcg gtagtatcta
    62341 tgagaaaatg caacgggtac aagtcattgc ccgtatcatt ggcgaacaag taggactatc
    62401 tgaggaagaa ttgatggatc tgcaacgagc tgctgaaatc tataaatttg atctagtaac
    62461 caacatggta ggggaatttc ctgaactgca agggatcatg ggcgaaaaat atgctctgct
    62521 gaaaggcgag aaacctgctg tagcgacagc gattcgtgag cattacatgc ctatatccag
    62581 tgaaggagag ctacctcagt ctacagtagg ttctgtttta gcgattgcag ataaattaga
    62641 tagcatcttt tctttctttg ctgttgggat gatcccaagc ggttcaaacg atccttatgc
    62701 cttacgtcgc caagcatacg gtgtcgttcg gatcatcgaa tcgaaaaaat gggcctttcc
    62761 tttgtctgtt ctgcaagaaa cgattagcga tgttatcagt aaagatacgg atcgtttcgg
    62821 cattggttta tcagaagggc aacaacaagt gatcgacttt atcaaaggcc gtctgcgcca
    62881 attattgaca acgaagaata ttcgtcatga tgtcatcgat gctgttttga atgcggaaca
    62941 aaaagatctg acaaaagtat ttgcagcagc acaattgttc aaacaacatc ttgcagatga
    63001 agacttcaaa ccttcaatgg aagctttgac acgtgtcgtg aacttagcga aaaaagcgca
    63061 gcttgaaaaa caatcagaag tagatcctga gctgttcgaa aacgacgcag agaaagaatt
    63121 acacaaagca gtagaagcaa tgaaagcaag ttttgctgac caaacgatcc acgaaaacta
    63181 cgaccagctt gtcgctcttc gtccactgat cgaaaattat tttgatcaaa cgatggtcat
    63241 ggctgatgaa ccagcagtac gtaagaaccg actaacacaa cttagtcaaa tagctgccat
    63301 ggctttgtca ttagcaagct tggatcaaat catcacaaaa tagtcttttg tttgaaaaac
    63361 agagagcatg cacgaaacgt gctgtgtctc tgtttttttg ttataaatat aaatagctgt
    63421 tattaattct attttaataa tttttgttat tttattcttt gttcgaattt tcaaaatgct
    63481 catgaaaaga gaggaaataa aaatgaaaac gattaatcat gatcttgtta ctgttttatt
    63541 tacttttaaa ttaggaattt ccctagtcaa gaaaactttt tgtggtatga ttatataggg
    63601 aaaacctgtt tataaatatt tctatgaata tattagttta attatgcttt taaaataaaa
    63661 agcgctcatt ctgatgggaa tgaatcacat ctttatttat ctatcatcaa tatttaggag
    63721 tgaatctatg gaaaagccgt tcgtcaagtt attggctact gtggcggtag gcacaggcgc
    63781 tattgtgatt tgcttgtttg gataccattt caataatcag cggcaacatc atcaacggat
    63841 caattacgca gaatctgcca tcaccaatca aaaagacacc gtgacctctt tatcaaaaga
    63901 agtagataag ctgtacagta caaaagaaaa aattttccta aatcctgaaa taacagaaga
    63961 aacagtttca aatttgtcac ataaactatc ttctatcaaa ctttcggcag atgattatga
    64021 catcaaggaa tcagaattac ctaaagaagc tgctgcgatc caagaagaaa agaaagcagt
    64081 cttaacgcag ttagaggatg cagaatcaaa actgaagatc cagacagctg tcaacgattt
    64141 atttactaaa aatgtatcaa actggcagca agctgtagac gatgtcgtca tcaaagaaaa
    64201 ggtgacaagt gcagatgtcg ctcgtgtacg tgaaaatatg agctttttta aagatagtcc
    64261 ttggaaaacg gttgttatgc aatatctagg attcgctgat actcagatcg cgcaagtcac
    64321 gcaactagat cagctattcg atacgatgct gaaagacggt caagtaacag ctactgctac
    64381 ttacgatcaa tatttgaccg cactcagtct catcgaacag atccggaatg aaaaaataag
    64441 agccgcatac gcgtcaaaag cagaaacagt cgctcagcaa atgggctata gcaatacgag
    64501 ctattaataa gcgagaattc aagcaaggct agcaaacgga ggaaactatg gcaaaacgaa
    64561 gaagaagatc aagagggaaa aagatatttc taattatttt agcaattctt gtcgtattag
    64621 tattagcaat cgtaggagta ggagcaaaat tatatctaga tctctcacat tctattgaaa
    64681 aaacttacga atcagtggaa cgaacccaag gagaacgaac aaaaccagtt gatctggaca
    64741 aacaagaatc tttctctgtt ctattgatgg ggattgatac gggagattta ggtcgggtcg
    64801 atcaaggaag atcagatacg atgatggttg ccacagtcag tcctgaagac aaacagacaa
    64861 cgattgtcag cattcctcgt gatacgtatg tcgacatcgt tggacatgac acaaaagaca
    64921 agatcaacca cgcttacgca ttcggcggag ctgccatggc gatggatacc gtacaaaaat
    64981 atgtagacat cccaatcgat cactatgttt caatcaatat gaaaggtcta aaagaactcg
    65041 ttgatgcagt tggtggtatc gaagtcaata atgacctcac cttctcacaa gatggctatg
    65101 attttacgat cggtaaaatc acattgaacg gggatcaggc attgtcttat tctcgtatgc
    65161 gttatgaaga tccaaatggt gactacggca gacaagaacg tcaaagaaag atcgtagaag
    65221 gtgtagcgaa aaaagtgttg agtctgaacg gtgtaagcaa ctatcaatcc gttttgaatg
    65281 ctctagagtc gaatatgaaa acagacatga gctttgatga aatgaaaaag attgctttag
    65341 attatcggga tgcatttggt acgatcaagc aagatcagct gcaaggagaa ggcttcatgc
    65401 aagacaatat ctcataccaa aaagtcagcg atcaagaact tgatcgtgtg aaaaaagaat
    65461 taaaagatca aatgaatcta gagaataaat aggaaagtgg agaaaaaatg gaagagacaa
    65521 tcagcttgaa agaaattttt gaaacattac gcaaacacgt gataacaatc ctcatctcaa
    65581 tgtttgctgg cttggccatc tcaggcatcg tgacgttttt catcttgacg ccaaaataca
    65641 gctcacaagc ccaattgatc gtgacactgc cgcaatcaga tactgcaaat gtcaatgatg
    65701 tcaatacgaa cctgcaaatg atcaatacgt ataaggatat gatcgtcagt gatctagtac
    65761 taaatgaagt caaagatcgt ttagaaacag aagacaatgt aaaaatgact gctggacaaa
    65821 tcaaagatgc catctccgtc aatcagtcac aaaattcaca aatgttctcg atccaagcaa
    65881 caagcacaaa tgcagtgacg gctcaacaaa tcgctaatac aacgtcacaa gtattccaag
    65941 agaacgccaa agacgtgatg aatgtcgata aaatctcgat catctcaggt gcagttgcca
    66001 atacgacacc tgtttcgcca aataataaat tgaatctagt gattggctta gtgttaggaa
    66061 tgatggtagg cgtaggtcta gctttcttat ttgaattact cgaccggaca gtaaaagatg
    66121 aaaaatatgt gacggataca ttgggcttcc cgatcttagg gactgtacca gaaatgtcag
    66181 cgaaagaatt gaatgctggt atccgtaaaa aaggaccagc tccgacacaa ccaaaagcta
    66241 caaacgataa aacagcgcca tcacgcagaa gccgctcaag agtctaggag gaaagaaaaa
    66301 tggcacgaac acagaaacaa aaagcagccc aaactcatgc agtcagtttg gtcacactca
    66361 caaacccctc ttcaccaatc gctgaacaat atcgtacgat tcggacgaat atccagtttg
    66421 cctccgcagc tggtcagcaa attaaaacga ttgttgtgac ttcatcagga cctggagaag
    66481 ggaaatcgac cactgcagca aacattgccg ttgtttttgc caaatctggt caacgggtgc
    66541 tgctagtcga tgcagactta cgtaagcccg tcatctataa aacgttcaag ttgaacaacg
    66601 caagcggatt aagtaccgtt cttagttcat caggaagtgt agcagatgag atccaacgaa
    66661 caccagtcga gaatttgtcg attctgccaa gtggacctaa accaccaaat ccatcagaac
    66721 tactaagttc gccaagaatg gatcagattt tagcagaagc aagacaacta tttgatgtag
    66781 tgatcttcga catgccgcca gtagttgccg taacagatgc acagatcatg tcttccaaaa
    66841 cggatggcac cttattggtc gtacgtgaaa atatgtcacg gaaagaatca ttgactaaag
    66901 caaaagaatt gctggatatg gtacaagcgc gagtccttgg tgttgtatac aatggggcag
    66961 aacacagcaa agatgctggc tattactacg ggaattaaga aataaaaaga gaggagacaa
    67021 gagaaatgat cgatctacat tgccatatcc tgccaggaat cgatgacgga gcagaaaaca
    67081 tagatgccag tatcgccatg gctgaaaaag cgattcaaca agggatcaca catattttat
    67141 gcacacccca tcataataat ggaaaataca gcaatgaaaa atcacaagtc atttctctag
    67201 tcgcttcgtt acaagcagaa ttagagaaaa gacaattgcc tttgacgtta ttggaaggac
    67261 aagaagtacg tattaccgga acactgatcg aagacatcga ccgagatgaa attttattta
    67321 cagatttaga tgatacatat cttctaatcg aatttccgac actggaagtg ccgttatatg
    67381 cagaacagct cttttttgag ttgttacaac taggaaagac accagtgatc gtccatccag
    67441 aacgcaacgc gcattttcgt aaagacccga atcatatgct gccattccta gatatgggat
    67501 gcttggccca actcaccgca ccaagttatg tcggtgtatt tggaaaagac atccagaaaa
    67561 cagccaaaat gatggtcaaa cataatcttg tgcagatggc tgcttctgat gcccatgggg
    67621 tctctaagcg taccttttac ttaaaagagt gctatgagca gattgctaag gactttggta
    67681 aggaaaaagt agtacagatg aaacaagtcg caaaggatct gatcaacggg gatgaaatca
    67741 gttatccagt ctatgaagag gtaaaaaaga agaagtttgg tttattttag ttctttattc
    67801 gtagataaaa aggaaatgag gagagaggga aagtatggaa agtgaagatt tattatctcg
    67861 tattagtgaa gtacatccta atcaagtttg gttggataaa gaaaaagttg aaaaacgata
    67921 tatctattta ttttttaaaa gaatgattga tattgtagga agcattattg gtttgatttt
    67981 agcttctcct ttgatgttct atgtagctta tcgaatcaga aaagaagagc caggaagtcc
    68041 gatatttttt tgccatacac gtgttggtaa aaatggaaaa acattcaaaa tgtataaatt
    68101 ccgttcgatg tgtttagatg ctgaagaaaa attggaagaa ttacttgatc aaaatgaaat
    68161 agaaggtgca atgttcaaga tgaaagaaga tccccgtgtc actaaaatag gtaaaattat
    68221 ccgtgccaaa agcattgatg aattgccaca gctatggaat gttttaaaag gcgatatgag
    68281 tctaattggt ccacggccac ctttggagag ggaagtagct gagtacacga gatatgatct
    68341 tcaacgcttg tatgtaaaac ctggttgttc aggtttgtgg caagttagtg atagaaataa
    68401 tgttagtttc cataaaatgg ttgagttgga tttagagtat attagtcatc gaagtttaat
    68461 gtacgacttg aggttgattt taaaaacgtt ttatgttatt gtcaagccca atggagcata
    68521 ttagttaggg atagaatgat ggattgttaa taaaaaagat tacacatgtt catattatcg
    68581 tttcaaaagt aataactgta attatggagg gtttgaatca cttgtagaaa atctaaaaaa
    68641 agaaaggtga atggggcaat tcagtatcat tattcttata taaaagaaaa tattcgaaat
    68701 tttgggatga taccactctt aaatataatg atctaaatgc tttaatattg gtatatccga
    68761 tataggaact gacgagctat ttagtatgat acaaaagtat attgatagcc attaataaat
    68821 tttccaaaaa ataatgacag cacaccaatt tttataattt agcttgttga atcggtatgt
    68881 tcatgggacg gttcaaaaaa agaatcgaaa aataaacggt aaacttttag tgaatcctaa
    68941 cggatatgag tggttacgag caaaagggag ttatccggtc ccaaaatatt gtaattattc
    69001 tgaaacatta atggaatggt atcaactgat aataacataa taagagataa aattgaggaa
    69061 tatctatcat tttataacaa agagaatgct gcagagtgtt tacttaaaat gtgggagtaa
    69121 ggtatttgtg actttagaag aggctatttt ttatctataa gaatttatta tccactgtgc
    69181 agaaatgaag attatagttc atctaaactt ttaaactttg taatatattg gatgttcata
    69241 acggaaaata atatttggaa aagtacgttg ttataaagta tgtaccacta tcttaaatat
    69301 tatgaaacta agacaatttt ttttgaaact atctatagat atatttactg gaatttttgg
    69361 aggtatagaa acagttatca ttttatcttt gtaccaccaa tgatttatat cagctcaaca
    69421 gagtgaattg tatttacgca agaatgcgta ggatgaaatg gatagataat taagatatat
    69481 atgtatatgg tgactgaaga caaaaaaaca gaactaatga aactgaataa aaatatagag
    69541 tgaactagtt tctaagaggg attttaaact agatttcatt ggtaataaaa tttggacaga
    69601 tggaaaaaca tcacataagg aagcagattt tgttgtcatt tttgttccta caaactatgg
    69661 tagtgaatgt gttattgaat tagtgatgtc tgttacttca gaggcattgg ggataattaa
    69721 atccactata cctgtaggat atacaaaaag tggaagaaaa aaatattatc aatagatttt
    69781 atttagttca gaatttttac gtgaaagtag attattaatg ataatcttta tccaattaga
    69841 attattatcg taggatgtga tgatgaaagc cgtgaaattg ttcaagtatt taccaatgtc
    69901 tccctgccag taaatccgct tagaatttga gccttgaaaa tgtgcaatga taaaaaacaa
    69961 aaactcgctc aaaatagaca gtttggggtg ggaatagacc aataatgtac caaacaaact
    70021 tccatttggg gtgaaaatag gtcaataaag cgatgttaaa catacctttg gagtaagaat
    70081 agagggtaat aagtgaattt ataaactttt tggtgactgg ttgagtggaa aatgtaggta
    70141 catttcaatg cgaaaatgta ttataacccc aaacgaggtc aataaaaatg actcaaactt
    70201 gcaatataac cctaaacggg taggggattt atgaaaaatt gaatttgccg gcgtaggagc
    70261 tggctgtttt aagtatgaat gaacacagct ttcgggctgt tttatataaa tagcaggtta
    70321 ctgttcacaa acagcatttt gttaagaaag tagtgaccac agcagtggtg gaaagaggaa
    70381 atattatgaa gaaacagtat aacattgcag tcgccggcac cggttatgtt ggtttgagta
    70441 ttgccactct gttggcacag caccataagg ttacagcggt ggatatcatt ccagagaagg
    70501 ttgaactgat taataaccgt aaatctccaa tccaggatga ttatattgaa aagtacttgg
    70561 ctgagaaaga actgaatctg accgcaacat tggatgcaaa ggcagcatac cagtctgcgg
    70621 attttgttgt tattgcggct cctactaact acaatagccg cactcaacat tttgacacat
    70681 ccgctgttga ggctgttatt aggctggtca tggaagtaaa tcctgatgcc attatggtta
    70741 ttaagtccac cattcctgtt ggatacaccg cttctgttcg tgtaaagact ggtagcaaga
    70801 atattatttt cagccctgag ttcctgcgtg aaagtaaggc actgtatgac aatctgtatc
    70861 cttcgcgtat tattgtgggt accgatatgg atgatgagcg tttggttgag gatgcacaca
    70921 cttttgctac actgctacag gaaggcgcaa tcaaagagaa tgtggacaca ttgttcatgg
    70981 gctttactga agcagaagct gttaagctgt ttgccaatac atatctggct cttcgtgtca
    71041 gctacttcaa tgagctggac acttatgcag agatgaaagg cttgaacact cagcagatca
    71101 ttaatggagt ttgccttgat cctcgtattg gtactcatta caacaaccct tcctttggtt
    71161 acggtggcta ttgcctgccg aaggatacca agcagcttct ggccaactac gcagatgttc
    71221 ctgaaaatct gatcgaggca atcgttgaat ctaaccgtac tcgtaaggac tttattgcgg
    71281 atcgtgtact tcagatggct ggttattaca attacgcaga agcaaatcag tatgatgctg
    71341 gcaaagaaaa gcctgttgtg attggtgttt accgtttgac catgaaatcc aattctgata
    71401 acttccgcca gagttctatc cagggcgtta tgaagcgtgt aaaagctaaa ggtgcaactg
    71461 ttgtgattta tgagccgacc ttgaaagatg gagagacttt ctttggcagt aaggttgtga
    71521 atgatttgga acagtttaag gcaatgtgtg attctgttat agcaaatcgc tacgatgctt
    71581 gccttgatga cattaaggaa aaagtatata cccgtgatat cttccagaga gactaagatt
    71641 aggagagagt atttatgatt attacaaaaa caccgtttcg tatgtctttt tttggcggtg
    71701 gaacggatat ggaggattat ttcaaagaga atggcggtgc agttctttct actacttttg
    71761 ataagtactg ttatgtgaat gtgagacatc tgcctagatt ttttgattac agcgctgagt
    71821 tatcttattc tcgtactgag agagtaacta gcattgaaga tattgagcat cctgcgattc
    71881 gtaatgcgat gaaaatgctc gatatgcatg aaattcggct tacatacgaa gctgatttac
    71941 ctgctcgctc tggtctgggt acatccagtt cttttgcagt tggtatgttg aatgcttttt
    72001 atgcactgga gggtaagtat gctgacaaga agaaacttgc tgatgaagcc atttatcttg
    72061 aaagagttct gtgtaatgaa gccggtggat ggcaggatca gattgccgca tcttatggtg
    72121 ggttcaatcg aattaatttc aatgtggatg gttatgaggt gctgcctgtc attatttcgc
    72181 ctgaacgtaa aaagcagctt aacaacaatc tgatgatgtt ctttaccgga ttcactagat
    72241 tttcttctga tgttcaaaag gctaacaacg tcagtggcac agaggataag agagtaagac
    72301 tgaaaaagat gtatgagctt gtagatgaag ctgaggcaat tcttactgat aagaacagaa
    72361 atttagatga tttcggtaga cagcttgatg ttacttggag attgaaaaaa ggtactggtg
    72421 gagcaattag tacaggaagc attgatgaac tatatgaaaa gggtatggct gcaggtgctt
    72481 taggcggaaa gttgctcggt gcaggtggtg gaggtttctt ggttttctat gtacaacctg
    72541 agaaacagga tgcagttcgt tgggctatgc gtgatttgat gtatattccg tttgaatttg
    72601 aaaatggtgg aactagagtt attcactaca cgccggaaac ttatattgaa aaacagaatg
    72661 gataaggagt aacaatgtta gcggaaaaac ttaataaaca tattgactta ttgattaaac
    72721 gatatcctac acttgagacg attaaacagg acattatcga tggataccta attatggagg
    72781 aatgctattt gaatggtggt aaacttcttg tggcaggaaa cggaggatca gccgctgact
    72841 cggaacatat tgctggcgag ttgatgaagc ggtttaagac gccacgtcct gtaagtaagg
    72901 aatttgccga taagttagtt gcaattgacc ctgtaagagg tccggaatta gccaaaaatc
    72961 tcgagtgtgg tttaacggca attcctttgg tcgcacacga agcattgtct actgcttata
    73021 ttaatgatgt cgatggtttg ggtgtcttcg cacagcagct gtttggcttt ggtagatctg
    73081 gtgacgtatt ccttggtatt tcgacgtccg gaaatagcaa gaatattatg agcgcaactg
    73141 ttgttgctag ggctctcggt ataaaagtta ttggcttgac gggcgcaaag ggtggggaac
    73201 ttgccacggt agcagatgtt tgtgttaagg ctcctgaagt tgaaacatac atgattcaag
    73261 agtatcactt gccgatatat cattgttggt gtttgatgct ggaagataaa ttctttggaa
    73321 acgaataaaa tttggaggaa tgttaaatga aaaagacaat tatggttacc ggtggttgcg
    73381 gtatgattgg ctccaatctt gttaagagac tggtgaagga aggctgctgg gatgtttatg
    73441 tagctgataa tctgtggaga ggaaagttgg agtacctgaa cgacgaagat gggcatcctg
    73501 tcatcgacct ggatactcat ttcttcaatg ctgatctgac tgattatgag caggctaaaa
    73561 aggttattgg tacgactgag tatgtagttc atctggctga tgttgtggct ggcattgact
    73621 atgtgtttaa gaaccagggc gaattgttcc gaatcaataa tctgatcaat tctaatgttt
    73681 ttgattgttg ccgtaaggct ggcaaggaga aaatcaaggg tgttatctat gttggtaccg
    73741 tatgctcctt ccctctgacc agacagaata ctttgaatcc tgagcctctc cgtgaagagg
    73801 agttgttccc tgctcttcct gagtctgctt atggctggag caaactgatg ggccagttgg
    73861 agatggggta tttggaaaaa gaaaccggaa ttccgtgctg tatcctgatg ctccataatg
    73921 tttatggcac acctactgat tttggcgaac gtagtcaggt tattcctgct ctgattcgta
    73981 aagcaatcaa taatcctgaa gagcctttta atgtgtgggg tagcggagag cagggacgtg
    74041 ctttcattca tgtcaatgat atcgtaaatg cattggtgct cgccctggat aagggttggg
    74101 gtcatggtca tattcagatt ggcccttctc actgtacttc catcaaggaa attgcatata
    74161 agatcattga aatttctggc aaagacatca agcctttctt tgatacttct aagcctgaag
    74221 gtgataaggc tcgttgcgca gattattcta aggcgaaaga gattttggat tgggagccta
    74281 ctgtttcttt ggaagagggt cttcgtgaat cctacaattg gattgaaaag cagattaagg
    74341 gttaataagt atataagctg ttcttcctcc gtgtaattag aggatgcgga ggaagaacat
    74401 atgagtaagg atgtactgag atggaaaaga atatgtataa aagaaaacgt gatttcactg
    74461 tgtgtggaat agtaggtgtt tgtgctacta caaagaacga gtttgtaagg gaagtttttt
    74521 ccatgccaac atctccggta agtgcgactg ttgatctcgt gggagtgccg gccattattt
    74581 cggcaaagga aaatcccaaa attgctgaaa tgtatagcca ggctacaatg gctgcaatag
    74641 atggtatgcc tattgttaaa attggacggc gcaaaggatt tacctgtgaa cgatgtgctg
    74701 caccagatat tatgggaatg gtttttgaag aaggcgttag acagggaaaa acacattatt
    74761 tctatggtgg aaaagataac gaagtgttaa ataagcttcg tgcaaaccta gaaagagatt
    74821 acccgggaat caaaattgtt ggaatgtatt ccccaccatt tcgtccgtta aatgaagaag
    74881 aggatagcaa gatttgcgag gaaatcaaca acttaaatcc agattttctg tgggttggta
    74941 ttggtgcgcc taagcaagaa atgtggatgt gggaacacca gaagaagatc cataacacag
    75001 taatgttcgg tgtaggcgcc ggctttaact tttttgcggg cactttggaa aaagctcctg
    75061 aatggatgga aaaagctagt ctagagtggt tatttagact ggtaaaggaa cctcgtagac
    75121 tatggaggcg gtatatcttg ggaggtataa agtatatcta ctatactatt gaatctaagt
    75181 aggggggcaa taaaaataga tgaaaatact tatagtagtt acaatgacga ataactttgg
    75241 taagaagggg tcctataatt ctcaggaaat aggattagct cgagggttag ctgaattagg
    75301 ccacgaagtt attgtatata aaagtgtaaa aagtgatgag gaagttggaa cagagcaatt
    75361 aagcaatacg gcgatgattc actatatcaa gtgtcgttat gtaggatcaa atggattctt
    75421 atcaacaaag aattttgata agaatgcgga tgttctaata caatttgcgg accttcaact
    75481 atcagtacct catgtatact catggactgt aaaaaatgga ataaaatata taccttataa
    75541 tgggataacg cgaagtcaaa gtggcaataa atatataaag acaattattg aaatattggc
    75601 gcatcgaaat tataaaattt ataagaaaaa tgggtgtgtt gccaaaaatg atcgagtttc
    75661 tgaaaaatta gtacaattag gagtaaataa agtgaaactt gctcctgttt gtgtggattt
    75721 tgaacagtta cataagaatt acgaagcaat agattttact actctcagag aaaaatggaa
    75781 tattcctcgc aatgttcgtg ttattttata tgtaggacgg tttgaaaagg ataaaagacc
    75841 gttagatatg attagtttat ttaataaact tgatgagcat aattatttgc tgatggtagg
    75901 aactggtgct ttactcgagc aaacgaagca gcagataaat ttacttggac tgcagaatag
    75961 agtaaaaata attgagcgta ttcctaacaa agatatttgg gagttatatt gcttatcgga
    76021 tgtatttgta aatctaaact atactgaaat ttggggtatg gttttgctag aggcaatgta
    76081 ctatcgcctc gggattattg ctgttaatgc acctggccca cagaatatta ttttggataa
    76141 tagatatgga atgttggcta aatctgacga tgaaattttg acattcttaa aagacggacg
    76201 atttaccaac gatatcatag atgcagcata tcagcgtgta actacagaat ttagatggtc
    76261 aaagtcggga gaaattatgc ttagcatgtt ggaaggtgat aaatgatatg gaagtaacga
    76321 aattaatggc attgaggaat cgatatgctt taaacatagt tgataattgc acgagaaaaa
    76381 tagccaaaat tcttggttgt tgtattggta aaggtgcaca gatagggaac tctgttgaat
    76441 ttgttcataa ttctgtaggc actgtgattc attctgacac aatccttgaa gatggtgtta
    76501 aagtctatca gaatgtgacg tgtggttgag cagatagtaa tgaacgtatc atcattcgag
    76561 taaaaaagaa cgctgtttta tgtgtgggtg ctaaaattct ttgtaaatct aacacagaat
    76621 tatgcgttgg ggaaggtgct gtagttgctg caaatacagt ggtattgagg tctattccac
    76681 cctacgaagt gtggggggta cctgctaaaa agatggggag ataaaacatg aatgcatata
    76741 aattatacaa agtagaacga tggttttact tacacaaaat ggagtttttt gccaagattg
    76801 taaaggcact aatttatgta cttcataata gctcaatttc atatcaaaca gaaattggag
    76861 ataattgtaa gttcttatac ggtggcatag gttgtgtaat tggaaaagat acaaaaatag
    76921 gtaatcacgt tataatcgga acgaatgtac tgactggtgg tagatccaat aagcctggta
    76981 tgcctacaat tggaaacaat gtatatatcg ctactggcgc aaaaatttta ggtaatatca
    77041 caatagggga caatgtaata gtaggggcta atgctgtggt cattaatgat gttgaaccta
    77101 attgttcggt aggaggcgtt ccggctagag tattgaaaaa agatattgat gtaaatgatt
    77161 attgtagttt gaatcgttac taaaaggaga gattgtatgt tgtattttgt tattccttta
    77221 atgagtgcga aggcagcaaa caattgggag atggttagta ccttatttaa ccgaacatta
    77281 tggtcgtgtt ataatcagac tgatcctgat ttcaaaatca ttgttgcttg ccatgaaatt
    77341 cctaaactca cgcatgaata tgatgacaga gttgaattta ttcaagttag cgaaaaggat
    77401 gcccctattc ccacaaatca agacgaaaaa atgattgata agggttataa aacacatgct
    77461 ctcgcaatgc gtttgcgaga gttgggcggc ggtttcgcta tgatggttga cgcagatgat
    77521 cttgtaagtt ctcatttggc ggaatatgtg aattcccatc cccaggaaaa tggattttat
    77581 gtcaaaacgg gatacgtgta ctttgttgga gacgattata tgaaggttct accaaagttc
    77641 tcatcaggaa gtgcgtgtat agtaaaatat gcagtggaag acctgcctga ggcatatccg
    77701 gaagttatga cagcaaattg tgatgataat ccatggatca ttagaaaacg acatgggggc
    77761 gttgttccag catgtgaaga gcaagggcgt ccattaaaac ctcttccatt caaagcagca
    77821 gtatatgtat taggaacagg ggacaatcac tcgctttatg gtaaaacgac aaaatatcag
    77881 acgaaaatgc gagagatact ggaaatgttt atagcaaaac gtaaaattaa aggaaaactg
    77941 aaagcagaat tttctgttga ttggttataa ggtgagtatt atgaaggtat tgatgtgtga
    78001 aagccaaatg ccagagaatt ggtattcgtt tgatctttct aaagaactta atcaatatgt
    78061 tgatttaaca ttgctgtgta agcgtgatgt tcctccttta gatcctaaaa ttaagagcaa
    78121 acatattttg tatcataaaa gtacaaataa agtgttttcg gcacttgttt ttctgaaaag
    78181 cttgttctta atttggaagg aaataagatt tggtgattat gatattgttc atttgcaatt
    78241 gatgaaaagt ctcaaatatg aaggcggatt gtacgtttta tgtaagagac actataaaaa
    78301 attaattatg acagttcata atgtgttacc acatgaggtt cgtgaaaagg atcgccaaga
    78361 gcactttaat atatattcaa attgtgatgg tttcattgtt cacaatcgag taacagaaca
    78421 gcatttatat gctgaattcc cagaattaaa tgcaaagtca tatgtttgtc cacatgctat
    78481 ctatggagat gttaaacata tatctagagc gtatgataaa gataagtttg aatttatctt
    78541 gtttggacaa attcgtccat ataagggaat tgatgtactg cttaatgcaa tcacagaact
    78601 tccaatggat gtaagaaaga aagttcattt taccatagca ggtcaacaac atcctaaaca
    78661 ggatagtact gactataaaa aaatgattga agatttaaag gtttcagatt gtgttctata
    78721 taagccagag agaatttctg atgaagaaat ggacagtatg ttcagaaatg cagatgccgc
    78781 aatatttcca tataaagaaa tctatggaag tggagcgctt cttatggcat acacttattg
    78841 cttaccaact attgttagta atgtacctgc ttttatggaa gaaaccgagg aaggaaagat
    78901 agggttactt ttcgaaaatt tgaattctaa gagcctagca gacacaattg taaagtatgt
    78961 gaaccttagc ccagctgaga aaagcaaaat agaggatgat atatatgagc ttgtaaaccg
    79021 caagtatacc tgggcggcat ctgcaaaact cacatacgag gcatacaaac aaattttgaa
    79081 tgagtagtaa aacaattaga aaggaataat aattaacatg cagattagta aatggaaaat
    79141 catacagttt ctaatggtct ttctaatgat tatctcatca agcatattga agcctttggg
    79201 cggctggttg ggagaaacga tgaacgttag acttgtgaca gtcattctag caatagtatg
    79261 tttgttaata gcctcattac cagcatttag aaaaaataga tatttaaatt tctgcacttt
    79321 actgatttgt gttgttataa tagcagctta catctactca gataagacaa tatgggttaa
    79381 atctagggaa agtatgagtt tatactatgt attattggcg tatccattgt tctgtacttt
    79441 aattaaccaa gcgtggaatt tggattcaat gctaaatacg atatgtggtg taacatttct
    79501 ttcatacatt cttagaacat ctatttcact tattcagaaa ttttcaggag tacttctcta
    79561 tgaaaacata tatcgtgagt gtgccccgga aaattggtat cgtggaggct ttttaagaat
    79621 taatccacca tgttttacaa ttataataat accgattgct ttgtatatga ttgagcgaca
    79681 agttgtagct agaagaaaag taaaatatta tttactgatt gctagcgcac tggcatattc
    79741 tgctgttatt catggttcta gatctgtcct tgtctatcaa attattgtac ttggttgcta
    79801 tatccttttt aagaaaggtt cttcgaaaag aaaaattgca atgtgggttt tagctgggtt
    79861 gcttgtagtc atatttatta attcgaccat gttctcaaca tttgttgaaa ctttcacaaa
    79921 cagtacaggt gaatatgcag gatctgctga atctcgattt gcttcagttt ggttttttat
    79981 tcctaaattt ttgcaatcgc ctttgttcgg tactggtatt cttactggtg aggaatttac
    80041 gtttatatta ccaggaggag ttagaggaca cctatctgat attggatttt tctatacaat
    80101 tactcaatat ggtgtaggta tacttatatt tgatattctg tttattataa aagggttcaa
    80161 aacagcatta cttgcatcaa aagtgggtat gactggctat caatatttag catttggaat
    80221 tacattaaat gtcttgctaa cagggattaa tatagactgg ttttatccga tatttactcc
    80281 agctattcct gtatgcttag cggttataga atacatctat caagaatgta gaagtgtggc
    80341 taacatagaa taggaaatat taataggagt gcatctcatg aataagaaag agattttata
    80401 taacatattg aagaagtacg aaaatttacc atatgtgttt aggaacatgt ttggtcataa
    80461 tataagtaaa ctcgtatctt ggaaattgac tgctgattgt gcaacagtag aagaaaattc
    80521 tgaagtttat gcagcgtttc aattgcgctc aaaggacatg tctgatgttc cagtgatggg
    80581 tttagttaat tgttgcaaag atgtagcaat tgtaatgcag gggccactat gtttaaagga
    80641 tgatttctct tataatactc tggcctacta taagaaatgt tatccaaatg ctttaattat
    80701 tctttcgaca tggaaggacg aagatattaa ggcattgaaa aggatagagg atcttggagt
    80761 tatagttatt tgtagtgaga aacctgaaaa gcctggacac ttaaatatta attatcaagt
    80821 tggaaacact ttgcctggaa tagtcagagc aaagcagctt ggtgcaaagt atgtttgtaa
    80881 aactagaaca gatcaaagaa tataccatcc aaatgcaatg gcgtttttct gcagtttact
    80941 tgaacagtat cctgttaata acgaagatga ttggaaatta atacaaaatc agcgattact
    81001 gttactatca atgccgtatg gagacatgtt tttcccgtat tgtttgtcag acttcctgta
    81061 ttttggtgat gttgatgata tgataaacct cttctcgatt cctagtgatg tgagagaaaa
    81121 gggagctgtg tctagaggag tctcaagaag ggagatatct gaaaataatt tagctccaga
    81181 agttcagctt cttcgaagct atatttcacg aatggggggc aatgaggagt gctctattag
    81241 ggcatattgg gagtttgtaa aaaaccatgt tattactatt aacaaaaatc aaattgattt
    81301 gtactggcat aaatatgtag gtcgttattc aaataatact atttatggta cgtattatat
    81361 tgatgatagc caagatgcac ttcactgcta taattttgat tttataaatt ggttgaattt
    81421 gtacactgga aaatacgaat acaaagcaga atatgaaaaa tatatggact ttgtttggga
    81481 agagtaatta acttttatag taaaaagtac tttagggaag ggcatattat gaaaacagta
    81541 attatggcgg gcggacgagg aagccgaatt tcggaattgt ttccggatat tcctaagcca
    81601 atgattccta tagatggcat tccagtttta gaacgagaat tgtgttcgct tagagatcaa
    81661 ggctttaatg atattatttt gactgtttcc tatttgcatg aaaaaataga ggagcatttc
    81721 ggagatggtt caaaattagg aattaaaatc aaatatttta ttgaaaaaac tccacttggc
    81781 aatgcaggtg cattgtattt tttgttggat gaactgggtg atgaaccgtt tttacttttg
    81841 aatgctgatg cagtatttga tgttgatttc aggcagatga ttagatttca tgttgagaat
    81901 aacgcagatg ttactttgtt tacgcatcct aactcacatc cgtatgatag tggattaatt
    81961 atatccgatg acaataagaa agtgcttcaa tggttagcga aggaagatca aagacctgaa
    82021 tattataaaa accgagtaaa tgcaggtctt catgttataa atccgaaggt gttgagagaa
    82081 aatccattaa tggaaattgt aaataaatca atagttgaag gtggggggct accatacaaa
    82141 attgatttag atagaatgat tctgaaacca ttggctaaca cagggcgtat gtattgctac
    82201 gattctccag agtatgttaa agatatggga acaccggacc gatatagagc tgtaattaag
    82261 gactttcaaa agggaattat tgttggtaaa aatctatcca atccacaaaa agcaatcttt
    82321 ttagatagag atggaacgat taataaatac gttggttttt tgagaaatgc agaagaattt
    82381 gagttaattg atggagtatc ggaggcaatt aaaattatta attctctagg ttttctgtgt
    82441 attgttataa caaatcagcc tgtaattgca agaggtgaag ttactgttga tgagcttaat
    82501 agtattcaca ataagcttga aacaatgcta gggcatgctg gtggattttt aaacggtatt
    82561 tattactgtc cgcaccatcc ccataaagga tatgcaggag aggttataga attaaaaatt
    82621 gattgcaatt gtcgcaagcc aaaacctgga ctgttattag aagcatcaaa ggattttaac
    82681 ataaacctaa gtcaatcatt tatggttgga gatagtgaaa gtgatgtaat tgctggaaaa
    82741 aatgctggtt gtaagacagt actgattaca gaagacatca ccttgcctgc taattatggc
    82801 caagactata gtgtctgttc attgttagaa tttgttaaaa atcatttatg cactatgcaa
    82861 taattggttt agtgaaactt gtaaaaggag taattagatg aaggtattaa ttccagcagc
    82921 aaaagttgtt gaaaaagaat tgcagagtat aggaatgtta ccagcaatta tctatccaat
    82981 taataaaaaa attgtctttg attatttgta taatcagtat aatgcaatct gcgattcatt
    83041 ggatattatc tgttatgaaa aagcggataa ggttcataga agactgaaaa actatcatga
    83101 ttccagaatt catatatgtg accttcctga attaggggat ctagggcaaa ccgtgtattt
    83161 tgggttatca gatgaagatg agcctgttct aattaacttc gcagatacaa ttgttatgga
    83221 gagtatgtct gatatagaaa tggatacatt ctattattct gaagattttg tgtcgagtac
    83281 ttggacatac tttaaaatta atgaaggaat aattactgat atccacgata aagaggaagc
    83341 ttacgtatcc gataaacgtg aaaaattatt tattggcgta tttatgtttt cttcgtcaaa
    83401 acttctgaag agttgcttaa gagaggcagt tgagagtcgg aaacaggggg gaataaactc
    83461 attttatcgg gctttacagc tatacagcga acgttgtccg ctaaaggccg taagaacaga
    83521 aaagtggttt gatattggac acatcgataa atattacaat acaaagttgg aagttaaagc
    83581 acgagagttt aatcatatct ctatagataa agatcgaggg atattgaaga aaactagcga
    83641 tgacaaggat aaatttattg gagaaataaa gtggtattta aaacttcctg ctgatattga
    83701 atatgtaaga cctagaattt ttgattattc tacatcttac gtagctccct atgttgatat
    83761 ggaatattat gcatatcata cggttcatga gttatactta tatggtgatt taaaatataa
    83821 ccagtggcat gatctgttta gccgtataaa gtttatctgt agcgatttta agcgatacac
    83881 cttaaaagat gaaaagatta gagagtcatt ggaagatatg tatttgcgaa aaaccatgca
    83941 gagatttcaa aaattgtctg aagataaaag attttcagct ttttttgaga aacaaattca
    84001 aattaatggt cgtaagttta tttctttaac cggtgtaatt gaacttctaa agaatcttat
    84061 cccaagtatg ctctatgatg taaatgaatt ttgtattata catggagatt tgtgttttgc
    84121 taatatgatg gtagattcca attgttcctt tgttaaggtt attgatccta ggggaaaatt
    84181 tggaaaatat gatatttatg gggacagcag atatgaatta gcaaaactat ttcatagttt
    84241 agatggtaaa tatgattata tcatcaagga tctatttact gtagaatatg ataccgagtg
    84301 tgcagtgata gattatacaa ttaatacgcg tgtaagagat tacgatttat ttgaattgtt
    84361 taagtcggtc ttttcggacg agattaagga cgattttgat aagattgtat tgatagaagc
    84421 gttgctattt cttagtatga ttccattaca cggtgaaagt tttgatcacc aaatagtgat
    84481 gcttgctaca ggtatggaac ttcttgcaag agtaagtaat aaagttatac tctaatataa
    84541 attgtgcctt aatgaataac ggttacaata ctgttttagc aatgtaggca ttaaggcacg
    84601 attatattaa ttaatacaat agaagggaag agaaaaatgt atagtgaata ttcttttgtg
    84661 tttgatatcg atggcacttt gtgtccgata aagaagaagg atgagcgata tgaggatttg
    84721 gtgccgtatg agaatatggt tgaaaaactg agattctata aggagaatgg tgctaaaatt
    84781 acattgttca cctcacgcaa tgttaattcc tataaaggaa atttgggaat gataaatgct
    84841 aatactgcaa aagtgctctt ggcgtggttg gataaatggg acattccgta tgatgaaatc
    84901 ctgtatggta agccttggcc ggggcataaa ggcttctatg tagatgatcg aacggttaga
    84961 cctgatgagt ttttgagatg ctctgtagat gaattaaatg aaatctgcaa cagttcaaaa
    85021 aaaagattct aaataaggag gttagttcta tggaaaaaaa gatgacagtt atcattacga
    85081 tggcaggttt gggaagtcgt tttcgaaaaa ttggttatgc ggttcctaaa tatatgatta
    85141 atgccaaagg aagaacttta tttgattggg ccatggatag tttggttgga tacaataaaa
    85201 atgttgataa gtatattttt gttgttcgtc aggaagacaa cgcttcagct tttataaagg
    85261 agcattgtgc ttactttggt attgaaaacg tagaagtgat tgaaatagac tatatgacag
    85321 atggtcaagc aactacatgt atgttggcta ttccttattg caatcaagac aatgagatta
    85381 tggtttacaa tattgataca tacgtggaat caaatgagat gaaatacgaa gatatttgtg
    85441 gagatggaca tattccatgc tttcatgctg atggcgatca ttggagtttt gcaaagctta
    85501 acgatcgaaa tgaagtaata gaagtccgcg aaaaagttcg catttctgat aattgtactc
    85561 ttggtgcgta ttatttctca tcggcaaagc tgtataaagc tttatatgaa gagtattatg
    85621 cagactcctc taatatggag aagaatgaaa aatatatagc accattatat aactttatga
    85681 taaaaaaagg gttaaaggtg actattagca tagtagatgc gaaaaaggtt catgtgcttg
    85741 gtactccaga agagctcaat gtgtttttga atcaagaata aatagtgttt aggagaaaat
    85801 agcagtgacc agtaataatc taattgtaaa aacattaagc agatataaga atactccact
    85861 tcctgttaag gctgcattat ggtttatggt atgtggtttt ttacagagag gggtttcaat
    85921 gattacaacc ccaattttta ctagagtttt gtctacagaa caatacggtt tatacagcac
    85981 ttatctatcg tgggaatcct tattgctcat gattacatcg cttagtttgt tcaaagccat
    86041 gatgaatctt tatgtaaaat atgataatca agaacatatt ctttcgacag tatccggatt
    86101 gactttagta ctgactattt tttggtttgt tattgctatt tttattaagg atatattggc
    86161 agaaatttta ggattgacac cagttctagt tgtctgtatg ttctcatatt ttatatttca
    86221 ggcagaaata caatgttggt ctttacacaa acgatatata tatgattata agactttatt
    86281 agtagctacc cttgcagtta ctgttggctc atctgtagtt ggctgtttag cggttctgtt
    86341 tatatctcct accgctgagg cgagagcctt aatgaatgtc ctagtgactg gtgttgttgg
    86401 cgtggctgtg tatatatcgg tatttagaag atgtaaggat tttaaggata atgaagtgtg
    86461 gaatttcgca gtagtatttt gtgtatcgtt gatgccacac tatttatctg aatttattct
    86521 gaatggttct gataaaatta tgataaatta cttatgtggt tcgtcagatg ttgctattta
    86581 cagcgtggca tattctattg gtgctctaat taaccttgtt acaaattctg tcaattccac
    86641 ttttgcacct tatcagtatc aaaaaatcaa gtcaggagaa tatgatttac tatcaaaaag
    86701 agctaatgaa gttcttggtt tggtagcggc tatgcttttt gcattaatgc tatttagtaa
    86761 agaaattgtg ttgatatttg gtgggcagaa atatatcgac agtgttaatt taattgtacc
    86821 tatatgtatc ggtatttatt tcaactatat gtttcagctg tttgctagag tacaggaata
    86881 ctttgaaaag aaactcactg tcgttattcc atcggttttg tgtgcaatta tgaatattgt
    86941 actaaattat gtttttataa agttatatgg gtatcaggcg gtagcataca caactgtatt
    87001 ctcatatatg tttttctgcg tcatccatta tattttttat agaaaagttt gcaaagaact
    87061 attggatgga aaaaacatat atgatgtcag aggaatactt ttgatttctg caatcacgat
    87121 agctggtggc atcctaattt caataattaa taaatttgat ttcataaaat atttaattat
    87181 agcaattgct tgtgtcgctg caattatatt tagaaaacga ttgctacttt tagtaaggag
    87241 aattatgagc aaataaacat ttgctcatag agagatagag aatgatagat attatttctg
    87301 ctataacggt aaatgtatta acagcattat atcagccgtt cttatttgcc gtattaacag
    87361 cgtatctgtt tatgtactgg tatctattta tagttgataa ctctcgagat cctaaaaact
    87421 taaaagattc tgtattaatc tggttgagat attttaaagc atctagtaaa tttcgcagac
    87481 tcttttttct tgcgttttat tttactttga tattatttaa aaccttgctt aatcgaaata
    87541 tgtggatgaa cccgctttca aacgttattg gacagtggtc attatatatt atagataatg
    87601 ctacaggaga gagcagattg acaacagaat gcgtggagaa cacgatgctg tttatccctt
    87661 tttgcatgtt attgttatgg tggcgtgaca ttaaatgtga tattatacgc accatctatg
    87721 ttgggattaa gtatgtgttt ttattctcat taagtataga atttacacaa ctgtttttta
    87781 ggcttggtac atttcaacta tcggatttgt tttataacac cctagggggc ttaattggtg
    87841 ctttgctata ttggctattc taccgattaa ataagtatat agacttaaaa tagaactgct
    87901 ttgaatttta atatggttaa tatttttctg cagacaggat tgtgtaatct catcaagaat
    87961 actttacatg ccatctattt ttgctaaaac attgttgtta tatcttcaag aggtagggaa
    88021 ttttattgct ttaaatgagg tcgagcgaat taaaaaattg gtaaaatata taacatggtg
    88081 gtagttatgg taaaagtgtt tgatataatt aagttttcgg atttcagagg atatactgct
    88141 gttgcattgg ataatgagac tcttttctcg attggtattg agtttcacat taagcaaata
    88201 aatcaaggat ttagtcataa taaatatact atgcgagggc tacattatca gagtggagag
    88261 catgctcaag gaaagatagt gatgtgccta catggtgaaa ttatgaatat cgcacttgat
    88321 attcgacaag gatcttccac ttatggatgt gtgtatgtca acacattgag tgaaagcaat
    88381 ggtaaatgtg cgtatatccc acgtggatat gctcatggct atcttactat ggaggacaat
    88441 acgctagttc agtggtgcgt agataatgat ttcaattcta atgctgccaa atgtataagt
    88501 tatgaaagcg tagatattga atggccggtc agtcggcagt gtttcgttat aagtgagaaa
    88561 gacaaaaatg tggaaagatt aagcttttga ttaaaatgag ctgtggagaa aagaaggata
    88621 ctggaaaata agaagaacaa taaccgagca aatgctcggt tatttctatg aggaatacat
    88681 aaaactaaat ttagatatag atatacccgt ggtgctagtt aattttaata tcctaaagaa
    88741 tatctcaaag ttccttcaaa acgtcgttgt gctcgactta atagaacact gtaagccagt
    88801 aatatgcttt caaatctact ctctagccct ttaacagaac gtgagttgaa attttgacaa
    88861 cctaattttt ctaaggaaga aaaaacagtc tcaactgttt
//
LOCUS       DAYYEF010000005        80798 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000005 DAYYEF010000000
VERSION     DAYYEF010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 80798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80798
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.005"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..355
                     /locus_tag="ACHA1B_000437"
     CDS             <1..355
                     /locus_tag="ACHA1B_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701232.1"
                     /translation="DLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLKN
                     DTEKPIRPQQWSIENKDGEELYEYAMILDNPEYIESDKEETVNYYYELPIERQDYQIV
                     VRRANGYFVGLPFTL"
     gene            432..746
                     /locus_tag="ACHA1B_000438"
     CDS             432..746
                     /locus_tag="ACHA1B_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701233.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDRIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSETFEIDPDYYQPQEVFREFRNQIIRSSNI
                     EN"
     gene            994..1923
                     /locus_tag="ACHA1B_000439"
     CDS             994..1923
                     /locus_tag="ACHA1B_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701234.1"
                     /translation="MRSDSRFFVSNLQDDELIRQIDSLLETITESDKRIFLNYVELTR
                     HIIELDKLFNVFRYNLTNLLKHFTIFTNDLIESTGEKLTEDQYYYQINALTINLISSA
                     KTLTESIEVCMKNFLAEKDFKSFKNKILSKPYDEHFSYRFLLHMRNYSQHGHLPVNIH
                     QQRVYFDLDEILAMPHFDFNGQLKKELDVLRKDIYNQFRDSPRISYVYTVAKFNLVIT
                     EIYFNYLKEIKPILIKLNDEKNELLLNTKFQLINSDGSSSDMLFYEFDGENYHCFNRK
                     DNSISMYADIKREVKKILKVEEQYYKEIEKRNQ"
     gene            2092..3417
                     /locus_tag="ACHA1B_000440"
     CDS             2092..3417
                     /locus_tag="ACHA1B_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701235.1"
                     /translation="MENIEETFLKVLSPYISDSILRFQEQEKNYKFGFDIKNYNDSLH
                     VVFQYNKTGKIGIKEVHIFQIFLAKVNIEASKSKLNYTTLLDTNALFFSKKLLPYLHS
                     YEWALRKLIYLLAPAYFSDNWAEESIPNEIISSIKRKQIQAIGKFDSKNLLQWIDLYD
                     FEEYLFGENYILVTQENEENIVRYKEISQDQLLKLFQDNSHTISDSYSLWSEVFSKYM
                     DVKLEEIQTDMSLIREGRNIVSHNKEIEMALYQKLIKKLKRYTNQLEKAFQKILAGDI
                     AGEDLSDMSDDFEGYIGNYFSNIDLAGVTKLSESLSAMKVLNTDSMKKSMESIGQTLS
                     VQQEIMQNFDTEGIRRATEGINQSLQSIKILNTDSMKRSIESIGQTLSALSAQRAIMQ
                     NFDTKGIRSATEGINQSLQSMKIVNTDSMKRSMESIGKISSTNQVLKSE"
     gene            3517..4335
                     /locus_tag="ACHA1B_000441"
     CDS             3517..4335
                     /locus_tag="ACHA1B_000441"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701236.1"
                     /translation="MVQGLFGGGTSYEGQSISDIKEDVNNWKIYTENVKSQIVEKKEA
                     LIKNGFWNKIPWNFQQTINESIFCLGTFLSDFQIVESAFEENFISEREIKLLRKIGKN
                     SVQFNHSYGKYFKEEYEWREYGNPEFEIVESIYQHGRDFFVTLQDASNAAGRLEDYMS
                     NNSIYNKVNIFGNSYNTNIQQGHNNNMIVSIDDMSELLSKLDLLLENLNDSLPEEEVE
                     EAQEYIETIKDEAIKEKPKKTMLRFAVDSLKKLKWSTEFLASVATIAQLVAPLL"
     gene            complement(4774..5919)
                     /locus_tag="ACHA1B_000442"
     CDS             complement(4774..5919)
                     /locus_tag="ACHA1B_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8701237.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(5980..6627)
                     /locus_tag="ACHA1B_000443"
     CDS             complement(5980..6627)
                     /locus_tag="ACHA1B_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8701238.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            6821..7114
                     /locus_tag="ACHA1B_000444"
     CDS             6821..7114
                     /locus_tag="ACHA1B_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701239.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            7158..7469
                     /locus_tag="ACHA1B_000445"
     CDS             7158..7469
                     /locus_tag="ACHA1B_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701240.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            7466..8090
                     /locus_tag="ACHA1B_000446"
                     /pseudo
     CDS             7466..8090
                     /locus_tag="ACHA1B_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            8231..8389
                     /locus_tag="ACHA1B_000447"
     CDS             8231..8389
                     /locus_tag="ACHA1B_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701241.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            8390..8752
                     /locus_tag="ACHA1B_000448"
     CDS             8390..8752
                     /locus_tag="ACHA1B_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701242.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            8789..9637
                     /locus_tag="ACHA1B_000449"
     CDS             8789..9637
                     /locus_tag="ACHA1B_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HFM8701243.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            9627..11102
                     /locus_tag="ACHA1B_000450"
     CDS             9627..11102
                     /locus_tag="ACHA1B_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VapE domain-containing protein"
                     /protein_id="HFM8701244.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            11368..11775
                     /locus_tag="ACHA1B_000451"
     CDS             11368..11775
                     /locus_tag="ACHA1B_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HFM8701245.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            11778..11993
                     /locus_tag="ACHA1B_000452"
     CDS             11778..11993
                     /locus_tag="ACHA1B_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701246.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            11997..12377
                     /locus_tag="ACHA1B_000453"
     CDS             11997..12377
                     /locus_tag="ACHA1B_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFM8701247.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            12511..12666
                     /locus_tag="ACHA1B_000454"
     CDS             12511..12666
                     /locus_tag="ACHA1B_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HFM8701248.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            12735..13208
                     /locus_tag="ACHA1B_000455"
     CDS             12735..13208
                     /locus_tag="ACHA1B_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HFM8701249.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            13205..14899
                     /locus_tag="ACHA1B_000456"
     CDS             13205..14899
                     /locus_tag="ACHA1B_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFM8701250.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            14865..15050
                     /locus_tag="ACHA1B_000457"
     CDS             14865..15050
                     /locus_tag="ACHA1B_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701251.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            15054..16229
                     /locus_tag="ACHA1B_000458"
     CDS             15054..16229
                     /locus_tag="ACHA1B_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFM8701252.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            16222..17745
                     /locus_tag="ACHA1B_000459"
     CDS             16222..17745
                     /locus_tag="ACHA1B_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFM8701253.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            17801..18085
                     /locus_tag="ACHA1B_000460"
     CDS             17801..18085
                     /locus_tag="ACHA1B_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFM8701254.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            18072..18407
                     /locus_tag="ACHA1B_000461"
     CDS             18072..18407
                     /locus_tag="ACHA1B_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFM8701255.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            18702..19328
                     /locus_tag="ACHA1B_000462"
     CDS             18702..19328
                     /locus_tag="ACHA1B_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701256.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            20070..20906
                     /locus_tag="ACHA1B_000463"
     CDS             20070..20906
                     /locus_tag="ACHA1B_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HFM8701257.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            20971..21405
                     /locus_tag="ACHA1B_000464"
     CDS             20971..21405
                     /locus_tag="ACHA1B_000464"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8701258.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(21473..22795)
                     /locus_tag="ACHA1B_000465"
     CDS             complement(21473..22795)
                     /locus_tag="ACHA1B_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HFM8701259.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(22949..24589)
                     /locus_tag="ACHA1B_000466"
     CDS             complement(22949..24589)
                     /locus_tag="ACHA1B_000466"
                     /EC_number="4.1.1.101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043883 - malolactic enzyme activity
                     [Evidence IEA];
                     GO_process: GO:0043464 - malolactic fermentation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malolactic enzyme"
                     /protein_id="HFM8701260.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            24919..25389
                     /locus_tag="ACHA1B_000467"
     CDS             24919..25389
                     /locus_tag="ACHA1B_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HFM8701261.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            26018..27121
                     /locus_tag="ACHA1B_000468"
     CDS             26018..27121
                     /locus_tag="ACHA1B_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HFM8701262.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            27405..28085
                     /locus_tag="ACHA1B_000469"
     CDS             27405..28085
                     /locus_tag="ACHA1B_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFM8701263.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            28175..29209
                     /locus_tag="ACHA1B_000470"
     CDS             28175..29209
                     /locus_tag="ACHA1B_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFM8701264.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            29223..29558
                     /locus_tag="ACHA1B_000471"
     CDS             29223..29558
                     /locus_tag="ACHA1B_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701265.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            29542..32022
                     /locus_tag="ACHA1B_000472"
     CDS             29542..32022
                     /locus_tag="ACHA1B_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701266.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            32078..33637
                     /locus_tag="ACHA1B_000473"
     CDS             32078..33637
                     /locus_tag="ACHA1B_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8701267.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            33634..34998
                     /locus_tag="ACHA1B_000474"
     CDS             33634..34998
                     /locus_tag="ACHA1B_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding oxidoreductase"
                     /protein_id="HFM8701268.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            35169..36239
                     /locus_tag="ACHA1B_000475"
     CDS             35169..36239
                     /locus_tag="ACHA1B_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8701269.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            36254..36922
                     /locus_tag="ACHA1B_000476"
     CDS             36254..36922
                     /locus_tag="ACHA1B_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701270.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            36942..37520
                     /locus_tag="ACHA1B_000477"
     CDS             36942..37520
                     /locus_tag="ACHA1B_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8701271.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            37923..38834
                     /locus_tag="ACHA1B_000478"
     CDS             37923..38834
                     /locus_tag="ACHA1B_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFM8701272.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(39090..40007)
                     /gene="rnhC"
                     /locus_tag="ACHA1B_000479"
     CDS             complement(39090..40007)
                     /gene="rnhC"
                     /locus_tag="ACHA1B_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA];
                     GO_process: GO:0006401 - RNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HFM8701273.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            40209..40646
                     /gene="zapA"
                     /locus_tag="ACHA1B_000480"
     CDS             40209..40646
                     /gene="zapA"
                     /locus_tag="ACHA1B_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HFM8701274.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            40704..41251
                     /locus_tag="ACHA1B_000481"
                     /pseudo
     CDS             40704..41251
                     /locus_tag="ACHA1B_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
     gene            41366..43726
                     /locus_tag="ACHA1B_000482"
     CDS             41366..43726
                     /locus_tag="ACHA1B_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HFM8701275.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            43813..44127
                     /gene="trxA"
                     /locus_tag="ACHA1B_000483"
     CDS             43813..44127
                     /gene="trxA"
                     /locus_tag="ACHA1B_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HFM8701276.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            44309..46075
                     /gene="uvrC"
                     /locus_tag="ACHA1B_000484"
     CDS             44309..46075
                     /gene="uvrC"
                     /locus_tag="ACHA1B_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0009381 - excinuclease ABC activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HFM8701277.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVMPLPDLILID
                     GGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPEFFLL
                     QRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITAATTE
                     ELQEIGLPKNVAQNVFDKLHQE"
     gene            46220..47119
                     /locus_tag="ACHA1B_000485"
     CDS             46220..47119
                     /locus_tag="ACHA1B_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701278.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            47112..48374
                     /locus_tag="ACHA1B_000486"
     CDS             47112..48374
                     /locus_tag="ACHA1B_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8701279.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            48537..50435
                     /locus_tag="ACHA1B_000487"
     CDS             48537..50435
                     /locus_tag="ACHA1B_000487"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042132 - fructose 1,6-bisphosphate
                     1-phosphatase activity [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HFM8701280.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(50734..51453)
                     /locus_tag="ACHA1B_000488"
     CDS             complement(50734..51453)
                     /locus_tag="ACHA1B_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HFM8701281.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     misc_feature    51643..51690
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF03071"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="sodium ion sensor (DUF1646 type); this
                     cis-regulatory element may regulate processes involved in
                     with the transportation of sodium ions; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF03071"
     gene            51790..52122
                     /locus_tag="ACHA1B_000489"
     CDS             51790..52122
                     /locus_tag="ACHA1B_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701282.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            52109..54112
                     /locus_tag="ACHA1B_000490"
     CDS             52109..54112
                     /locus_tag="ACHA1B_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HFM8701283.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            54131..54601
                     /locus_tag="ACHA1B_000491"
     CDS             54131..54601
                     /locus_tag="ACHA1B_000491"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HFM8701284.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            54622..55206
                     /locus_tag="ACHA1B_000492"
     CDS             54622..55206
                     /locus_tag="ACHA1B_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HFM8701285.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            55221..56207
                     /locus_tag="ACHA1B_000493"
     CDS             55221..56207
                     /locus_tag="ACHA1B_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046961 - proton-transporting ATPase
                     activity, rotational mechanism [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HFM8701286.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            56197..56508
                     /locus_tag="ACHA1B_000494"
     CDS             56197..56508
                     /locus_tag="ACHA1B_000494"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HFM8701287.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            56530..58311
                     /locus_tag="ACHA1B_000495"
     CDS             56530..58311
                     /locus_tag="ACHA1B_000495"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HFM8701288.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            58304..59680
                     /locus_tag="ACHA1B_000496"
     CDS             58304..59680
                     /locus_tag="ACHA1B_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HFM8701289.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            59687..60322
                     /locus_tag="ACHA1B_000497"
     CDS             59687..60322
                     /locus_tag="ACHA1B_000497"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HFM8701290.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            60352..61707
                     /locus_tag="ACHA1B_000498"
     CDS             60352..61707
                     /locus_tag="ACHA1B_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFM8701291.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(61899..63293)
                     /locus_tag="ACHA1B_000499"
     CDS             complement(61899..63293)
                     /locus_tag="ACHA1B_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFM8701292.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            63385..64356
                     /locus_tag="ACHA1B_000500"
     CDS             63385..64356
                     /locus_tag="ACHA1B_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFM8701293.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            64353..65135
                     /locus_tag="ACHA1B_000501"
     CDS             64353..65135
                     /locus_tag="ACHA1B_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HFM8701294.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(65304..65675)
                     /locus_tag="ACHA1B_000502"
     CDS             complement(65304..65675)
                     /locus_tag="ACHA1B_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM8701295.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            65809..66252
                     /locus_tag="ACHA1B_000503"
     CDS             65809..66252
                     /locus_tag="ACHA1B_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFM8701296.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(66295..67104)
                     /gene="yidA"
                     /locus_tag="ACHA1B_000504"
     CDS             complement(66295..67104)
                     /gene="yidA"
                     /locus_tag="ACHA1B_000504"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HFM8701297.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(67123..68490)
                     /locus_tag="ACHA1B_000505"
     CDS             complement(67123..68490)
                     /locus_tag="ACHA1B_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFM8701298.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(68474..69304)
                     /locus_tag="ACHA1B_000506"
     CDS             complement(68474..69304)
                     /locus_tag="ACHA1B_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HFM8701299.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            69467..69904
                     /locus_tag="ACHA1B_000507"
     CDS             69467..69904
                     /locus_tag="ACHA1B_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HFM8701300.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            69980..70600
                     /gene="rpoE"
                     /locus_tag="ACHA1B_000508"
     CDS             69980..70600
                     /gene="rpoE"
                     /locus_tag="ACHA1B_000508"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HFM8701301.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            70789..71295
                     /locus_tag="ACHA1B_000509"
     CDS             70789..71295
                     /locus_tag="ACHA1B_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFM8701302.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            71312..72211
                     /locus_tag="ACHA1B_000510"
     CDS             71312..72211
                     /locus_tag="ACHA1B_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsiV family protein"
                     /protein_id="HFM8701303.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            72298..73182
                     /locus_tag="ACHA1B_000511"
     CDS             72298..73182
                     /locus_tag="ACHA1B_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFM8701304.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNYTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(73374..73445)
                     /locus_tag="ACHA1B_000512"
     tRNA            complement(73374..73445)
                     /locus_tag="ACHA1B_000512"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(73410..73412),aa:Arg,seq:ccg)
     gene            73505..74839
                     /gene="rpoN"
                     /locus_tag="ACHA1B_000513"
     CDS             73505..74839
                     /gene="rpoN"
                     /locus_tag="ACHA1B_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HFM8701305.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            74988..76079
                     /locus_tag="ACHA1B_000514"
     CDS             74988..76079
                     /locus_tag="ACHA1B_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HFM8701306.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            76120..77121
                     /gene="gap"
                     /locus_tag="ACHA1B_000515"
     CDS             76120..77121
                     /gene="gap"
                     /locus_tag="ACHA1B_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFM8701307.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            77231..78421
                     /gene="pgk"
                     /locus_tag="ACHA1B_000516"
     CDS             77231..78421
                     /gene="pgk"
                     /locus_tag="ACHA1B_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HFM8701308.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            78525..79280
                     /gene="tpiA"
                     /locus_tag="ACHA1B_000517"
     CDS             78525..79280
                     /gene="tpiA"
                     /locus_tag="ACHA1B_000517"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HFM8701309.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            79396..80694
                     /gene="eno"
                     /locus_tag="ACHA1B_000518"
     CDS             79396..80694
                     /gene="eno"
                     /locus_tag="ACHA1B_000518"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000015 - phosphopyruvate hydratase
                     complex [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HFM8701310.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        27208 a        13646 c        16778 g        23166 t
ORIGIN      
        1 agatttaaaa ataggtgaaa cttatcaggc agatggggtt gaactaacat ttaaaaatat
       61 tgaagtgacc gaaaaaagaa atgaatttgc acaacatgat cgtgtattac aagtgaccta
      121 tacacttaaa aatgatacag aaaaaccaat acgtccacaa caatggtcga ttgaaaataa
      181 ggatggtgaa gagctttatg agtatgctat gatattagat aatccagagt atattgaaag
      241 tgacaaagaa gaaacagtaa attactatta tgaattaccg attgaaaggc aggactacca
      301 aatcgtagta cgtagagcga atggttattt tgttggatta ccctttactt tgtaagtctt
      361 attttgttag tggcttttaa gttaatatca tttttgtgat ttttgaaaat gaaagtgagg
      421 aaattggaag aatggctgaa gaaaataaag ttgttccgtt tgaaacatta gtgataaata
      481 aggaagagtt tgagcaactt tttcttgatt tttttattca atatgacagg atttatgatt
      541 ttagttcgtc actagattta tttgaattag aagcagaaat aatagaaaac agtcgagaga
      601 agaatggtaa aatcattatt tcagtagaaa aattcaatga attattctca gaaacatttg
      661 aaatagatcc agactattat caaccacaag aagtttttcg agagtttaga aatcagatta
      721 ttcgttcaag taatattgaa aattgagtca ataaaagaag cgttgaagaa aagttccttc
      781 tttcgacgct tctttttaaa agattttaca aatgtcttat ggagatttgc ttcaatgact
      841 acttgtagtc atttcgttta aaataattat gttacaccct tatgtgtcac agagaaatac
      901 tgatataata agaaataagg tatgtaacaa tagagtatac ttctatgtta catattgatt
      961 attttgaaaa aatcatatta ggagaatata attatgagaa gtgatagtag gttttttgtc
     1021 agtaatttac aagatgacga gctaataagg cagattgatt cattattaga aacaataaca
     1081 gaatctgata aaagaatatt tttaaattat gtagaattaa cacgtcatat tatagagttg
     1141 gataaacttt ttaatgtgtt tagatataat ttaactaatt tgctcaaaca cttcacaatt
     1201 tttactaatg atttaattga aagtacaggt gaaaaattaa cggaagacca gtattattat
     1261 cagataaatg ctttgacgat aaacttaatt agttcagcca aaactttgac tgaatccatt
     1321 gaagtttgta tgaaaaactt tttagcagaa aaagatttta aatcttttaa gaataaaatt
     1381 ctgagtaagc cttatgatga gcatttttcg tataggtttt tattacatat gagaaattat
     1441 tctcagcatg gtcatctgcc agtaaatatt catcaacaaa gagtgtactt tgatttggat
     1501 gaaattctag caatgcctca ttttgatttt aacggacaat taaaaaagga gttagatgtt
     1561 ttaaggaaag atatatataa ccaatttaga gattccccac gtatctctta tgtttataca
     1621 gtagcgaaat ttaatttagt aataaccgaa atatatttca attatttaaa agagatcaaa
     1681 cctattttaa taaagttgaa tgacgagaaa aatgaattac tactcaatac caaatttcag
     1741 ttaattaatt cagatggaag ctcaagtgat atgctttttt atgagtttga tggtgagaat
     1801 tatcactgct tcaaccgaaa ggacaacagt atatctatgt atgctgacat aaaaagagaa
     1861 gttaaaaaaa tattaaaagt agaagaacaa tactataaag aaatagaaaa aagaaaccag
     1921 taattaacac agttatcaag gtaaagaaaa agttctcttt ctgtttgcta gttgtggctt
     1981 atgtagcaaa tatcaagtta ataggaaaat taaaattgtt gaaaggaaag aagttgatga
     2041 catattagta agcaagttgt tgaatattta tattatccta aaaaaggaag aatggaaaat
     2101 atcgaagaaa cctttctgaa agtgttgtca ccatatatta gtgattctat cttaagattt
     2161 caggagcagg aaaaaaatta taaatttggc tttgacataa agaactataa tgattcgtta
     2221 cacgtagtat ttcaatataa taagactggt aagataggaa taaaagaggt acatatattt
     2281 caaattttcc tagctaaggt caatattgaa gcaagtaaat caaaattaaa ctacactacc
     2341 cttttagata caaatgcgtt gtttttttcg aaaaaactat taccgtattt gcatagttac
     2401 gaatgggcat taagaaaatt aatctattta ttagctccgg catatttttc tgataactgg
     2461 gcagaggaat caattccaaa tgaaatcatt tcgtcaataa aaagaaaaca aatacaagca
     2521 ataggaaagt ttgactcaaa gaatctttta caatggatag atttatatga ttttgaagaa
     2581 tatctctttg gagaaaatta tattttagtt acacaagaaa atgaagagaa tattgtaagg
     2641 tataaagaaa tatctcagga tcaattattg aagttatttc aagataacag tcacactata
     2701 tctgattcat attctttgtg gagtgaagta tttagtaaat atatggatgt taagctagaa
     2761 gaaattcaaa cagacatgag tttaatcaga gaaggtagga atattgtaag ccataacaaa
     2821 gaaatagaaa tggctttata ccaaaaatta ataaagaaat tgaagagata tacaaatcaa
     2881 ctagagaaag cttttcaaaa aatattggct ggagatattg ctggtgagga ccttagtgat
     2941 atgtcagatg attttgaagg atatattgga aattatttta gtaatatcga tttagcaggt
     3001 gttactaaat tgtcagagtc tctatcagca atgaaagtat taaatacaga ttccatgaaa
     3061 aagtcgatgg agtcaatagg tcaaacatta tcagtccagc aagaaattat gcagaacttt
     3121 gatactgaag gtatcagaag ggcaacagag ggaataaatc aatctctaca atcaataaaa
     3181 atattaaata cagattccat gaagaggtcg atagagtcaa taggtcaaac attatcagct
     3241 ttatcagctc agcgagcaat catgcaaaac tttgatacta aaggtatcag aagtgcaaca
     3301 gagggaataa atcaatctct acaatcaatg aaaatagtaa atacagattc catgaaacga
     3361 tcgatggaat caattggtaa aatttcatca acaaaccaag tattgaagtc agagtaaata
     3421 aaacaggaac gatggcaatc atgttaccac acgaaatgct atcatttgta gcaagtattg
     3481 gatttagagt aattattata gagaggatga gataaaatgg ttcaaggact ttttggtgga
     3541 gggacttctt atgaaggtca atcgatttcg gacattaagg aagacgtcaa taattggaag
     3601 atatatacag aaaatgtaaa atcacagatt gttgaaaaaa aagaggcttt aattaagaat
     3661 ggtttttgga acaaaatacc atggaatttt caacaaacta ttaatgaatc aatcttctgt
     3721 ttaggaacat ttcttagtga ttttcagata gttgaatcag cttttgagga aaattttatt
     3781 tctgagagag agataaaact tctaaggaaa attggtaaaa attctgtgca atttaaccat
     3841 agttacggaa aatactttaa ggaagaatac gaatggcgcg aatatggaaa tccagaattt
     3901 gaaatcgttg aatcaattta ccaacatggg agagattttt ttgtgacgtt acaagatgca
     3961 agtaatgcag caggacgact ggaggactat atgagcaaca attcaatata taataaagta
     4021 aatatatttg gaaatagtta caacactaat atacagcaag gccacaataa taatatgatt
     4081 gtttctattg atgatatgtc ggaattatta tcaaagcttg atttgctttt ggagaatttg
     4141 aatgattcct tacctgaaga agaggtagaa gaggctcagg agtatatcga aaccattaaa
     4201 gatgaagcta ttaaagaaaa gcctaaaaaa actatgctga ggtttgcggt agatagtcta
     4261 aaaaaactta aatggagtac agaattctta gcttctgttg caacaatagc tcaacttgtt
     4321 gctccactgc tataagtgga gaatgaggtg ttcttcaatt aaccgacttg ccaagttgtg
     4381 gtaatggttt gagataatga aagctttgta ttctatagag attgatgtat ctgaatgaat
     4441 gcttgttttt ttggatatag ctgattaatc agtggtgtta cattatttat aagtcgtttg
     4501 attaactagt tcttacgatt tcttatcaaa agcacgccac gcaacttgaa tacgtttttg
     4561 aatacgacta aaaaaccact taaggtgaat tagacttaat aaagtgatta gttctattca
     4621 aaaatcgttg aaataccaac tatcgtcaat tatctttaat gagcttaact tcatggcgga
     4681 agaagaagaa tagactataa agctaggaga aaccttgata tgatagggtt tctccttttt
     4741 ttatttttta ctgtatgcca tattgtatgc catctagtca atatttaagt gttgtactaa
     4801 tttttcaaca gtcttttctt tcgtttcttt tgccaagtga ccgtaacaat cgatcgtctg
     4861 actaattttt gtatgccgta atctagtttg aacttctacc atagtagctc cagcgtccaa
     4921 gagcattgaa gcatgagtgt gtcttgctac atgcacaccg agaaatggaa ccatagcttt
     4981 ttcacaaata gtaatcaatc ttgcataaat agcgtggtgt gtgattagtt ctttatagat
     5041 accacaaaaa atcatagtcg gatcagttac accaagtgtc agcatatatt tccgctgatt
     5101 aatctgccat ttttttaata tagaaattgt tctttcatct agtggaagaa ccccagcact
     5161 acaatcagtt ttaggatcac tgattttata gccatttttg gattggctta gtgttttatt
     5221 gatggtgacc gtattttctt gaaaatcaat gtctgaccaa ttcaatgcaa gggcttcact
     5281 gatcctaacc ccgctataaa agagaaagcg tagtaacgtt ttatcaaagt cgtttcgata
     5341 agtttcaggt ttgctgttta ggtaatcaaa caaggtgatc agttgttctt tactgtaaac
     5401 tttgaccttt tctttatgct tagtggtggt tcttttaggc attaatacgt tgtctagtgg
     5461 attagtctca ataatcccaa gattgatagc gtagctaaaa atacgcttag aagttgaatg
     5521 aagtaccttg tattggtcag tagtttcagc ccagctattt acaatttgtt gggctttttt
     5581 taccgtgact tcattcacac gaagatttcc atattttgga agaatccact ttctaaactt
     5641 gatttcagtt ttcatgaagg tggcttctcg gacagtggtt ttatatgttt ctagccacaa
     5701 gtcataaact tctttaaacg tttcgttgtt cgctttttta ataccgtttt tatcgtagtc
     5761 cacttgcaag cgtgacaagg caagctgggc ttcttttttt gttttgtaac ctcgtctacg
     5821 aaccttatca ggtttgccag tcattttgtt cattccaaga taggcttcat agagccaaaa
     5881 tttacctttt ttagtttcat attgcttgaa tgttgccata atagttttcc ctccatagtg
     5941 tagcaagccg tgggggcggt tggaggaggc agtttattat tattttgaat agtgtttatt
     6001 tagctcagta acaagagctg tgaactcttt tagaagatca ttttcataaa attcttgata
     6061 ctcttttttc tcatctgtat ttttttctga atcattaatt aatgagtcat atcgtaaaag
     6121 cgtatttaga agagctgcga gataagcaat tggggtactc ccgtcaggaa attcaattcg
     6181 agatcctgtt ttaagatatt ttattgcgtt tgttaaataa atcttctgtg agacagtcag
     6241 gttatcttct tcgatgttat tgatagcatt agaaagatta gaatcaatta tagagttatt
     6301 tttttcaata gtttttttca attgcttttc aagcacattt cgcttaattt cgggcatcat
     6361 atgcatatct cttaatgtat aagatccgtt taatagatag gtagtggata catctaatac
     6421 ctttgaaagt tgtttaagcc tggtgttatt gggaagatta tagccatttt cccaattact
     6481 aacggcacct ttactggccg gtggggataa tttacctcca agttgttcca ttgagagtcc
     6541 cttttcaatt ctagccagtc taattctttg tcctgtctcc actgcttcgg ggtatttttt
     6601 tctagccaca ttttcaccac cattcatata ttttctctac tatatcacga tttaaatatg
     6661 tgtgaaacat aaaagttcaa aaaagtatgt taaaattctt gcaaatgaaa aggtatgatg
     6721 gtatattgag tttataagag gtatagaaat gtattcaaga gcctcttgca tttttttaaa
     6781 atctttgtat agaaatgtat gctaacgagg ggggataaat atggaattaa aaattgacaa
     6841 actcacgctt gatgatccag cttttaaaat tattgacgat cgagttgttc aacaagtaga
     6901 gcaaactcaa ggaacgttac tttcattatt agaaaaaaag taccagtttc caaaatatat
     6961 gaacaaggca caagctgcta agtatatgaa cgtttcatac aatactatga tgcagaaata
     7021 tgttcctaac ggtttaaagt tgattatagt tgatggagtc gtaagaattt cacaagatga
     7081 atgtgatcgc tttatggaag aataccaaaa ataaacgcaa gccgtggggg caaagggatt
     7141 aataggagga aataataatg gaatcgacac aaaataaagc aatcgaaaaa gtattatcaa
     7201 caattcttac agaagacaca gcggcagaat tagcaaactt ggaaggcaaa gcgctagaag
     7261 aaacgtttga atgtttgtac gaacaaatgg actatcaaaa attgctacca caagaaccaa
     7321 cggtaagcgg agtattgcgt ggcttgaacg atttagtaca agcagagttt aaagaacgac
     7381 tttctattga agagtatcaa gaaattttgt atcagcaagt tgagttgtta gcgagcttgc
     7441 tagggcttga actggaggac gttgaatgaa aactgaaatt tggaacggac acattataag
     7501 atttgtcgat attaatgatg aatggtgggc agtggcgaaa gatgttgcgg aagcgttagg
     7561 tcttaaacag gttactagag ccattcactc tttgcctaaa gatggggtta ctactagtaa
     7621 ggtcatcgat tcattgggca gaacacaaga tgtaaacatc atcaacgaaa aaaaatattt
     7681 accgcatggc attcaaaagc cgtaaaaaag aagccgaggc atttcaagac tggattttcg
     7741 acatcatcaa agaactacgc cagtccacag gacttgaagg ctttcaagta ttccgcatgc
     7801 tagacaaaga acaccaaaaa gaagcaatga ctaaattaag ccacgctatt actgaaccaa
     7861 aaccagtaga ctacattaaa gcgaatgtga tagccaataa agctgtatca actatttatg
     7921 gtcattccaa aatggtaaaa aagaaagata tgactcctga aatgttggtt gatcgtgaac
     7981 ctattttaga tgagacagta gaattaatga ctgttaaaga aaaatatggg ttgcagtttt
     8041 cagtgagtga gaaaatttat aatcgttctg ctgaattgca gacaacttag gagcattaac
     8101 atgatcgaga acaaagaaaa agccttatcc ataacagtct tggcggacag gataaaggca
     8161 acttaattgg gataaaaccc gatattcttt gttccgatta taccatatta aaaaatcgga
     8221 gggaaccatt atgaaacgaa acttaattat aggaagcatt ttaatcggcg gaattttcgg
     8281 cttattacca ttaattgcaa aaatagctat ctttgcagga ttagcgttat atctcttcac
     8341 tgcttatgac gagtacgact atcaattaag aactggaggg cataagtaga tgtacaaaac
     8401 aaaactatta aaccaactcg atagccttga attagaggaa attaatcaag ggatcgctga
     8461 actagaaaat aatatcggga aaacctactt tggaaattca ttcaatgaaa aactaacagt
     8521 tttgtatgta ctcaaaaaac atgcagaaca caaaataatt tgtcgagaaa tcaacgagct
     8581 aaaaaatcag attttaaccg catggttaaa cattactgat atgcaagaag caagggtgaa
     8641 aacatttaat acatgggtaa agtatcagaa tcaattaaaa ggtgctgaat ttgttcggga
     8701 tgggttgaaa tacgaacttg agcagttgaa gctcatggag gtgtctgaat gatttatacc
     8761 agtattttga aaaaggagga gaggtttatt ggcaaataat tatcaagcag caacggaatt
     8821 acaaaagtcg ggatggtcaa tttatccctt atctcctgga actaaaattc caataaaagg
     8881 ctctagtggt tggaatgatg caactaacga ttctaatcaa attaatgaat ggtggacgga
     8941 agatgcaact agaaatattg ggttaatgct tgaagatcat caaatggtgg tagttgacct
     9001 agatcaacat tctgaaacac gaaacggcgt tgagaattat aaaaaacttg cttcaatgta
     9061 tgatccattt ccttctactt atacggaaat cacaccaggt aaaggaatcc atttcttctt
     9121 taaaattcct gatggtgtaa ttatccaaca agaaacaggt gcatttgctg atatcttcgg
     9181 gcgtgatgat aaaggtaaaa gtttaagcgg gattgatatt atcactaaag gagttccaat
     9241 agcgccaact atgattattt caagaagtgt tgggagagca tatgaaccta ttgaaaacgt
     9301 atctctaaat aatattgcac cagctcccga ttggctagtg aacctactgc taaaaaaacc
     9361 gcaagaaata aagactcaat accgacccgt agcaaaaaca gggacagcaa aaaaattaga
     9421 tatgattgtt caaggcgctg gcgaaggtag tagaaacgat catttaacta agttatgcgg
     9481 ttggttacta tggcacggtg tagataatca aactttagca gaattgattt atacagcaaa
     9541 tgcgtacaat gaaccaccgc taaaagataa agaagtgaat caaattattc gatcgatgat
     9601 taaaaaagat ttgaggggga aagctcatgg ctcataagca taaattagat agtattttag
     9661 actttcccga agccagcgag cgtgaagaca atatcattga attgaaaacc tggatgtcac
     9721 gattaagatg caataaagac gatcagatta aaagtaacag tgttgtgaat gcagaattga
     9781 ttttaaccaa tgatagcaat ttagctggaa caattgctta taacgaattt agcggataca
     9841 ttcacctatt aaaagattct ccttggatca atcgtaccgc tggagaatgg gaagacagtt
     9901 ttgaggatgc cttaacggca tatattgaag aaaactacaa tgtagttttt gatgacaaca
     9961 aaatacacaa agcagtagta aatgtggcta gaaagaatgt tttcaaccca gtaaaagaac
    10021 gtatcgaaaa agttaaatgg gatcaacagc ctagactgga aacactgttt attgaccttt
    10081 taggggtaga cgacaacctt tacacacgag aagtaacaaa acgttggata gtcggatcag
    10141 tcgcacgtat ctataaacca ggaataaagt ttgagatcgt tccagttttg gatggaccgc
    10201 aagggattgg taagagtacc gttccagcat tactttacac ggatgatttt ttcaccgatt
    10261 cattagattc gctaggtgaa aagaaagatg attatatgca gcttcaaggc aatgtaatta
    10321 ttgaacttgg agaattatct tcaatgaaca aaactaaaat tgaacagata aaaaacttca
    10381 tcagtgccaa gatcgataaa attagacctc cttatggtcg gaatgtcata gcttgggcaa
    10441 ggcaatgtgt atttattgga acgtcgaatg atgggcagta tttgaaagat gatacaggaa
    10501 accgccgttt ttatcctttg ccttgtaaga ataagccaaa gatgaatccg tttaaaacaa
    10561 aggatgaata ttttcttcaa gtgttagctg aagcaaaggt gctttttgat aaaggacaac
    10621 gaatctattt tagtcccgat gaagataaag aagtcttaga aattgcaaaa gactatcaag
    10681 aggatgccaa gatggagaat ccaattaaag aagcaatcac taaatatttg gaaatggaaa
    10741 tcccgtataa atgggaagaa gctccagcgt gggcgagacg ttcttattat cagaactatc
    10801 ctgacagtaa atgtaatgag aaaaatttac agcatttcta taatggagct actatgcaac
    10861 aagagtttta tttagttgat agcgtactca ccgctgatat tttggaagct gtttttgata
    10921 aacaagcaaa ggatttattg aatggtcgat cagatgcaga aactaaaaag attgccttga
    10981 ttattagcag tattcctggt tgggaacgga agcaactgcc aaaaagaaat aaacgacgag
    11041 gattttacaa taagtcaaat gcctatgaaa ataaaaatcg agctggaaag tacaaaaagt
    11101 aacgggtagt aacgggtcag taacacctag cccgttacta gtttaccctt actgccccaa
    11161 gggatacagc aatttggtaa cggggtaaca ccttatttcc ttaaaacttt tgaaatagtt
    11221 agctaatatg ctggggaata atgttactgg attttacccg ttacctgtta ccaaaacgct
    11281 agaacccttg tccccgttgg gattgagtgg taacgggtac ctgttacgta ggtgttacca
    11341 cgtgttacga atcaaggagg aaagtaaatg ctcaatatta tttcaacaaa caaagcaccg
    11401 aactttcaat atacagatga aatggatcgg tttctaatga acacgctggc atttagtgtg
    11461 ggattggtaa cagaagatta ttccacattt gatccagaag tattaaagat aatggaagaa
    11521 gaacctgatt ggctgcagga gtcagtagcg tggtgtcaat cgctagtagt gggatcattg
    11581 gtagatagtg gcaactatga tgatacaggt gagctaatgg atgaatttaa ttgtctgctt
    11641 aacctatatg atcgagcgag acaacgagag cttacatcga atgaggataa tttgttttta
    11701 aacatccatg ataagttctt ggctttgcta ctaacagatg atgaattgat aactaattta
    11761 ttggaggtag aataattatg catatggaaa gtattagata cttcgatggt gagaaacaca
    11821 ttgagtattc aaacactcaa gaagatgtag actttattag ttttgaggaa gataaaatca
    11881 ctaaagttaa ttttaaagac ggaacgtgct tgaagatagt ttcgccttat attgaataca
    11941 aatcaaaatg ggaacaagat gattctgacg aacgagatcg ctttggttgg taatctatgg
    12001 cagttaaaaa acaatgtaat catgctggat gtaaaacatt gattgattat aggcagaagt
    12061 attgtgggaa gcataaagca aagcaaacgg caattaagcg tgaagaaaga aagcaaagcg
    12121 aaggtaaata ttttcaattc tatcaaagta gaacatggcg aaaggcttca tacttgtatc
    12181 ggttaaatca tccagtatgt gaggattgcc tagaagaagg cttgataagg aaagctgatg
    12241 ttgtagatca caaaattgaa ctaaaagatg attggaatag acggttagat gaaactaatt
    12301 ttcgttcttt atgccatgca caccataatt ccaagacagc caatgaaaga caaagacgag
    12361 aaaagagtac cctttgagtt aagggggcat agtgtgaaac ttactgacaa tcgatgccta
    12421 ctcattttgg tacaaataac cgttgtgaaa aggcataagg gtaattacaa ataacgatta
    12481 cacttgtaat cacaagtgaa aaagtatata atgaaagtag gagatttatt gaaaaataca
    12541 attgttatta ctgataaaac agggaaacag cgcaccattg agttacctca ttttggtcaa
    12601 gtgaccattc aaatgcagaa cggaaaaatc atttatatag ataaattaga taaagaaaaa
    12661 ttctgatcga aaaacgaagg aatgtgagct taattgctta cgttcctttt tcttttgtct
    12721 gaaaggagga caacatggga caccctaaaa tattacacga tacaaaaggc aatatatcaa
    12781 gtgaagaaaa agcaatccgt gtggacgcta gagaagaatt gttcaagcag caaccattaa
    12841 taaatatcac gccccctgac tggatggcag cgagcgctag aagtgaatgg aatcgtatcg
    12901 taccaacatt aaaaaaagat tatccattga gtgaagcaga ttatggttca ttggtagcct
    12961 attgtttagc ctttgctcga atgaaaacag ccgaagccga gataagaaaa tcaggtacgt
    13021 ttatcacatg cgaaaacgga gtaaagaaag ccaatccagc ggttcgggtt caatcacaag
    13081 ctatgagtga tttgaaaaaa caagccacct cactaggtat gaccttagaa tcacgatcaa
    13141 aactagcttt gaacaaggtt aaaaatgatg aacccgaaga cccgttcaaa gagttgatga
    13201 attcatgaat gattacattg agaaagtcct atcaggtaag ctgattgcac ccaagaaaat
    13261 tatccaagcg tgtgagcgtc atataagcga tttggagcgt tctaagtcag atagcttccc
    13321 ttatgtgttc gatgaagaac aagccaccaa agcgattaaa ttcattgagt tgctaccatc
    13381 tacggacggt aaagcaatca agatgttagg atttcaaaaa ttcattctag gcagtcttta
    13441 tggctggcgt actaaagaag ggaattacag gcgattcaat cgagcgttta ccagtatgag
    13501 ccgtaagaat gggaaaacgt atatcgcaag tggcatggct gccaatgcgt tgattatgga
    13561 acaagaacca gcagaagcaa ggcaagtatt gtttgtaagt aacgctttga aacaagctaa
    13621 attgggctat gatatgctgt ctaattcact tagaaacgtg gtcaagtcta gtaagttttt
    13681 aagaccacaa ctgaaaatta tgaactctaa gattcagcac ttgccctcta attcgttcgc
    13741 tatggcactg gctagtgaaa ccagcacgct agatgggttt gcaccaacaa ccgcaattct
    13801 tgacgagtgg cacgaagcaa aaactcgtaa aacgtacaac gtcattaagt caggaatgac
    13861 ccaacaaaag aacggcttat tgtgtgttat tagtaccgct gggcttgatt taaacgttcc
    13921 tatgtacgag gaatacttat tgttagatcg tgtgctaaaa ggcgaagaac aagccgacag
    13981 gtactttata gcgatatggg aattggacga tcccgaagaa attcacgatc aagagaaatg
    14041 gatcaaagcc aatccgattt ttgaaagtga agaaatcaaa aaagtaatga ttccaaccat
    14101 tcaagatgat gtgaaccttg ctttgaaaca aaataacctt aattctgtat tggtgaaaaa
    14161 cttcaattta tggagacaag cgagtgagga cagctatatg attgctgaag actggcaggc
    14221 aaccgaagta gaaccacaag atattacagg caagcccgtt tatatcggag tggatttatc
    14281 taaaacagat gatttaacta gcgtttcatg gatcgtaccg ctagataacg gcgaacttta
    14341 ttgtgattca catagctttg tagccaccaa atatgggctt caagacaaag aaaagcgcga
    14401 cggtttgcct tatcgagaac tagaaaaagc tggtgagtgt tccattactc aattagaaag
    14461 tggaatcgtg gactatgacc aagtatttca gtttattcaa gatttgattc aagaaaatga
    14521 tttggaatgt atggggattt gttatgaccc gtataacgct aattcgctta tcagtaaagc
    14581 tgaaaaagcc aactacccaa tgttagaagt aagacaagga acgattactc taaacgttcc
    14641 gacccgaact tttagagaac aagtttatga aggcaacgtt attcacaata aaaatacgat
    14701 tctcacccat gcagtgaaca acgctatttt aaaaacggat aacaacggca ttcagattaa
    14761 taaatcaaag aacagtaaca aaattgatcc aatagctgca ttaatcaatg cctatgtgtt
    14821 tgcaatggat tacttcacca caacggaagg agcgaaagca gacaatgaat tttatacaag
    14881 tgaagaattt tctttctaat tacattcata ccgttctttt acttcttgga ttggtgtgtg
    14941 tgttggttgc tatcacctta ctaacaaatg tctactatgg cttgttagcg ctgggcatag
    15001 tgcttattgg ggtagcggtc atgctaaata cagaacagaa gggaggttaa aagatggcat
    15061 tttttaaagc gagacaaaat acaacgggag atcctttcct acaacatgtg gtatcaatcc
    15121 aatcggatga ttacaccacc agctttacaa gcgttcgtgc attaagaaat agtgatgtgt
    15181 ttgcagccgt tcgaattatt gctagtgata ttgcttcaag tccgattcaa ttggtcaaaa
    15241 acaatatgcc acaagctgat aatgaactgg tgaagttact aaacgagaaa cctaattcag
    15301 aaatggatgg ttggcattta aagtttgctt tggcggtcaa tatgttgcta aacggtaata
    15361 gctttgcaga gattaaacgc aacggtgaaa aggtagaaga aattcactta ttacctaact
    15421 caagtgtaac ggttactcaa ttagataatg gtacgttgtc ttatcagatt ggtgataaaa
    15481 aaagacgtgt gaagtctagc gatattttgc acttcaaata tttcacccaa gatggtttaa
    15541 caggattacc accactttat gcgttacgtg atgaactgaa aattcaacaa gctggcaacc
    15601 gcacattgca caatttcttt actcgtggtg tcagtgggtc aggtattttg aaggttcata
    15661 agtcagattt agacggatca gcaaagaacg caattcgtga aaagtttgaa gaagccaacg
    15721 gttcaagtag tggagataat gctcttagaa cgatcattct tgatgaaaca atggactaca
    15781 aaacattaga aataaacacc gatgttttga agcttatcaa ttccaatgat tggaacacaa
    15841 aacaaattgc caaggcgttt ggtgtaccga ttgagcgttt aggcgttgaa aatgaacatt
    15901 ctagcaccgt tcaaagtaat ctccagtata tccaaagtac gctgattcat tactttaatg
    15961 tgtttgtgag tgaattagat acgaaacttg aaaccaatat ccgctttaat tccgatcagt
    16021 tactagagac tgatcctgaa acaaaagtaa aaaatgtatt ggatcaggtc aaagggtcac
    16081 ttctcacgat taatgagggg cggtcgaaaa tggggctacc ccccatggat ggtggcgatc
    16141 gtttactagc aagtttgaac tttacgtatt tagatacgtt ggagaaatat caattaaaag
    16201 aacaggaagg agttacacca gttgaataat gaagaagaaa aggaaaaacg gctgacagaa
    16261 gaagctgagc taacagccga ttctcccaaa gtagagaaag aaaatgaaaa acaaccaaca
    16321 gacggcaaaa ctatttcagg ctatgcgttg aaattcgggc aaccgtcaaa agatttaggc
    16381 ggctttgtag aagtgattac acccgaagca ttaaaagagg tggatttatc aaatgtgttc
    16441 ttattatatg gacacgatta ttcaaagcca ctagctagtg tcaaagcagg tacgttgaaa
    16501 ttgaatgtcg atgatacagg attacatttt gaagcagagc taaccgacac gacctattca
    16561 aatgatgtgt atgagaatat ctcaaaaggg gttgttgatt ctatgtcctt tgggttcgtg
    16621 cttggattag attcattcga caaaaaagaa gatggcacaa ttgaacgatc aatagataaa
    16681 atcaaagcac ttaatgaaat tagtgtcgtg accgttcccg cttatgattc atcaaatgtc
    16741 caagtaaata agcgttctta cgaatcgttt atgagtaaca accaagcaaa acaaacaaac
    16801 aatagcttag aatccacttc taaagcacaa aaggagagta ataacatgga aaaaacttta
    16861 atcgataacg aaaaaacaga attgcgtggg tatgaagaat atatccgttc acaaggcgaa
    16921 gtgcgtgatg gagtcactac tgtaaatgca gcggcagttg ttcccgaaga agtaatcggt
    16981 gaagtctttg atttgaaacg ttcaaattat aacttagctc aatatgcaac agtaaaaaca
    17041 gtatcaaatg gacaaggtaa atatccagta gcaactaacc aacaagcagt gttagcaaca
    17101 aaagctgaac ttgctgaaat tggtgatatt gacgctgaaa tgtttacttc agttgattat
    17161 aaagtagaaa ctcgtgctgg taagattgcc ttatcaaatg aggttgtgga agattcagca
    17221 gtgaatattg tacaagaggt caaagatcag ttagcgaaat tggtagaaaa cactgacaat
    17281 aagcatatca tggatttatt aaaaacattc actaagaaaa cggctgctac gttggacgat
    17341 ttgaaacaac tatacaatgt ggcattagac ccagcattaa ataaaatggt aattctaaac
    17401 caaagcggat attaccacct agatacattg aaagattcag atggacgtta cattttacaa
    17461 cccgatgtga cagcacctag tggtaaatca ttattcggta tgccagtagt attgattgca
    17521 gatacattgt ttgccaatcc taaagctgga acattcccta tgattatggg ggatattgca
    17581 caatctatct ttgttgctcg tagaaatcaa gtaacgactc aatgggaaaa attcgattac
    17641 tactcacaag gacttgcagt gatcgttcgc aacgattata agaaaattga tcaaaatgct
    17701 tcagtgtata ttgagtttac gccagttgta acaccaaaag tatagaaaaa tattgggcgg
    17761 cggtttatcc cactgccttt ttttcattag gagagataaa atggtaattt tggatagcat
    17821 aaaaaaaagt atgcggatcg atcacactat tgatgatgac tttattcaac aattgattga
    17881 tacagcaggc gaatatataa aaagtgctat tgatagtagc gcaacggata aagatatgga
    17941 taattatcag caatttgatt tggcggtgtc attacttact caacattggt atttgaaccg
    18001 tcaagaagcc agcagcgaac ggataccagt aacggtacaa gcattagtac aacaaatgag
    18061 aggtgcttat tatgccaatc attaagaatg taaatgaatt gactgagaga gtcaagttta
    18121 aaaagacaaa acgggtaaaa gatgaagatg ggcagatggt ggatagtgaa gaaactgtat
    18181 ttgaatgttg ggctaatgtg cgttcacaaa tgctaaaaga cgtgcttgct agtgtaggta
    18241 ccattcttga aggaacgttg acgtttatta ttcgatacga tcaagattat gaactaacaa
    18301 acgatatgaa agtagcttgg aaaaacaaga gttataaaat tatttcaatc aatgaaggaa
    18361 cggcgtttaa agattataca acgatcatag ctaaacagat ttcttagaat gattacactt
    18421 gtaaacgttg tgggtattta gtataattaa ggtagtaaat gaagggttag ctgcctgaat
    18481 tttgcaagac ttagctagtc gaaatctatt gttggactga aaattgtagg tgtggttgca
    18541 aacatgctgg actaagaaag atgatagatg atgaacgttc aattttaata caggcatgct
    18601 aggactgatt ggatggtttt ggcaagctga ttgtgtagaa atcaaagaac acgtctgttg
    18661 tggacgtgtt ttttttgtta taattcaaaa gaggtgattt aatggacaaa gcagagttta
    18721 caaattttta ttggaagtat tatctacatt tagaaaatga gtttattaat accacagatt
    18781 ttgtgatgct cgatgagaat aatttcaaaa cattctctat tgaatatcaa aaactactac
    18841 tagcgattgg ttcggagtgt gagattattt tcaaagaact ttgcggattt gatagcagta
    18901 gcaataaaag cataactgat tttaaagctg ttattaaatc tagcgaatta atgtgtttgg
    18961 ataatggtgt tagggttatg aattctttaa cattgacttc actaaaacct tttggagatg
    19021 ggtggcctga agatacacca gattggtgga aaatatataa cagagtaaaa catggtcgtt
    19081 cttcaaatta taaggaagca aatttggaaa atgtgttgta tgctttagca agtctatatt
    19141 tattagagga atatttgcat aagaaagtaa tactagaagg tgaagtagac tttataagtc
    19201 cagagtcaaa tctatttacg ttatcttggg aaagaaaaca ttcgtcgatg caaaaagtga
    19261 cgtttgaaaa agtggattca aattatgtag ctccactcat tgattttaaa gaacaagaag
    19321 aaatttaaaa acccccacgg cttattgaag tttttgtatg ccatattgta tgccatttgg
    19381 tttaaatcgc ttgaaaaata gtgatagata actctaattc atttagtcat aaacgctgtt
    19441 ttgataacct ttatagttct ttgatatggg tttctcattc atggcggaag aagaagaata
    19501 gaacaaaaga atgaattaat aagatataaa aaaagggatt gtgacaaacg tcttgtcaca
    19561 atcccttttt ccaaataaac gatgttcaat cagctgcccc tcggcattcg ctcgaaaaac
    19621 ggcgaaatat gaagaactat tttgccattt gtttctctaa taatcaggtc aaaacgttga
    19681 cttcacagtc tcttccttaa acggtgttct cctgccaact cctcggtcac aagtcacaat
    19741 attcaacaaa catgagaagc tgttttttga aattgttcct tgtgactcgg agctgaacgg
    19801 caggctcacg acctctttct taaacggtgt tcaaaagctt gcatctgcgg taataagttc
    19861 aaccaaacga aaattatgag gagctatttt tgtttggctg ttcttattac ttgatgcagg
    19921 acagcttttt cacaacctct tttcgtttag cactaaattt ccttaaaaag tagaaaagct
    19981 ttcgaagcct cgtttgtttc ttttactgta taataaaaga aaagagtaac aatcgctaaa
    20041 agatataaac aagagaaagg aaatacaaga tgattggtct gatttatttt gtggtgatcg
    20101 ttctggcgaa cacagttggc gctatttccg ggatgggtgg aggcgtgttg atcaaaccga
    20161 ttcttgatct tatcggcgcc cattctgttg cagggatttc tttttactca acagttgcgg
    20221 tattcacgat gtccattgtt tcgactgtgc gacaagtatc aagcgggaaa tcactgaatt
    20281 ggcagattgt cggttgggta tctagtggag ctgttgttgg aggagtagtc ggcaacattg
    20341 tattcgaagt ttttttacag ttatttgaaa acgagaagca tgtgcagctg atccaaattt
    20401 ttttgacggt attgaccttg gtttttgcgt tcttctacac caagcatcat cagccaaaat
    20461 ttcatttgac gtcatggact tggtacctta tatgtggggg ggttctgggc tttttagcta
    20521 gttttttagg tattggtggt ggaccagtca atgtttcttt gttgatgctg atgtttgcat
    20581 tgccaataaa agaagcaaca ctatattctc tatctacgat tttcttttct caactggcaa
    20641 aattggtaac gattgcttta acaagtagct ttatgcgctt tgatttatct atgttgtttt
    20701 atgttatccc cgctgctgtt attggaggtt tgtggggagc aagatttagc agggttttgt
    20761 ctccaaaaaa agtgaccttt atttttcaag taattgtcct cgtggttctt ttggtcaatt
    20821 gttacaatgc ctttgtcatc ttacaaacat taggagaatc tagactaacg caagtcaaaa
    20881 tcactgaaac atattgttct aaatgaaaaa aagagtatac tatgataaaa aaattcattt
    20941 taaaaaatca gaaattggct ggtgatttgg atgttacggg aaatgcgttt agaagatgca
    21001 gaagcactac gtgaaatcaa tgcggatcaa ttagggtatg atataccatt aaccgttacg
    21061 gtgagacaaa tgaagaaact gctgaaggag ccagagaaaa attttttctt ggtttatgaa
    21121 gatcctactt ctaaaaaagc agctggctat gtacaagcgg agtcctatga atcgattttt
    21181 agcgatccaa tgttcaatat tatggcactt gctgtgtcta aatatgctga aaaaagaggc
    21241 atcggaaagg ctttgatgac tggcgtagaa gaagaagcga aaaaacgagg aataacgaca
    21301 ataaggctta attctgcaga atacagagta gaagcacacc aattttatga acacatcggt
    21361 tatcattccg ataaaatgca aaaaagattt ttgaaaatcc tgtaaatctt tatcaaaaaa
    21421 atacccgatc accaagccga tacttgatga tcaggtattt ttgttttttt gactaagaaa
    21481 gtaattgcat caagaaacca gagatgatca aaacgatggc accaccaagt cgattgccca
    21541 tttgagcaaa agcaataagt tccatccgat tagctgcaga taagacggct acatttcctg
    21601 ttccgcccat cgagttgttg cataagccag cagtaatagt tgattcaatt ggatataaac
    21661 caaacaaacg accgacaaat cctgaaacaa ctgaaatcgc gataacactt gtcagacata
    21721 agacaacaaa ttgccatgtc aaagcagaag ctaatacatt cagattcagc aacgcaatac
    21781 cgataccggc aagaacagct gctgtcaagt ttttgacaat caagttattg aacatgatag
    21841 ctgcatcttc ataatactct ggtaataggt tggcgatttt acagatgaca acgataataa
    21901 tcataaatgc gtaagcatgg actttaggaa caaaatagtt accaatttgt cctaagatga
    21961 agaaagtcaa tgataccatc aaaccaacac ctaactgtgg aatggaaggt ttcacagttc
    22021 gaggttttcc atcgccaaga tcgccttttt ccattaattt accattgccg ttgaattttg
    22081 gcattgattg tccagcacga gcaactaatg ctgcaccgat gatagctaag acatttgtca
    22141 ttgctgtcgc aggaatcagg cgggaaatga tagaagaagc atccgtacct aaaacatttg
    22201 cataaatcgt tgataaagga acggctccgg ctccaacacc accagccatc gcaggtaatg
    22261 agatgtataa aacggaattt gcaaaaccat ttccgataag catgcccacg agtcctacgg
    22321 caaaaaagga gacgaccatt gaaataagtg caacgggaat aaaacgaaca gaagctttca
    22381 tcaatagatt acggttcata ccaaggatgc taccagtaat caaggcagca atataaaagt
    22441 cccaaaagcc catattgctg acaaagtttt ctgtggattt cactacatat tcaggtaaga
    22501 tcccaaatgt agcaatcgca gcagaagcga agatcgcaaa aacggaacca ccacccaaat
    22561 aacttttgac gatagggatt tttgtcccga taaaatgaaa taaattaccg aaaataacca
    22621 aaactgcgat tggtccaatc atattcgtcg gtaatttccc taaagccatt gcaatgatca
    22681 ggacaaggac catgatcaaa taaagtggca aacttacgcc ggtgattttt gtggaccaaa
    22741 aaccttcttt tttcttttcc tcaactgcag ttgcagttgt tgttttttgt gccattttta
    22801 cagatccttt cttattctgt atcatatgaa aaaagccaaa gaaaagcgac aaaagagcag
    22861 gagttggctg gccgctgttt tgccgcagtc gcttttttct ttttagacgt catacaaagt
    22921 ttctgtatgt tcttttacta taacgatctt aatcttctaa agatttatat tcaggaaccc
    22981 atttagcaga ttcaactgct tctttgatat ccgtgatttc ttcacgattc aagttttgtg
    23041 cgacaactga ttttgcgaca gtttcagcaa tcgtttgaga aaattcagtg atttttgcta
    23101 ctggaggcaa gatagctgct cctggttttg ttacatcaac gattccgcct aatgctcgac
    23161 tagcttgaga aatgatttca gcatttactc gtgtagctgt tgaagcaatc aaaccaagtc
    23221 ctaaacctgg gtacatcaaa gcattatttg cttgaccgat ttggtaagtt acaccattat
    23281 attcaacatc agcagcaggg atacctgttc caactaatgc ttttccgtcc gtccattcta
    23341 ttaaatcttt tgcttttgct tctgccaatt ttgttggatt agacaaaggc atgatgatcg
    23401 gacgtggtgt atgagcagcc atttctttca cgatttcttc agtgaatgct ccaggttggg
    23461 tagaagtacc aatcatgatt gtcggatgga tcgcttttac aactgcttct aagtttgtca
    23521 attcatcagc attagtgaaa tctgagcgtt tgcgagcgaa tgggatttga ccaggagtca
    23581 atccttctgt atcttcaaac aataaacctt gtttatctac ttgatagaaa tgttggcgtg
    23641 cttcttcttc aggtacacct tgacggatca tctcatctaa aaggatgttt gcgataccca
    23701 caccagcagt accagcacca aatgtcaaaa ttatttgatc tttcaattgt tcaccggata
    23761 tattcaatcc gcctaataca cctgctagga caacaattcc tgtaccttgg atatcgtcgt
    23821 tgaaagtagt gatttgatct tcgtattttt ctaagatcgc tgcagcattt cctcgtccaa
    23881 aatcttccca atgcaataac aattctggga ataattcggt agctgattga acgaattgat
    23941 cgatgaattc atagtaagtt tcgccttcta cacgagcatg acgattgcct aagtataagg
    24001 gattattcaa taattcttca ttattagtac cagcgtcgat cgatacaggc aaaacttgtg
    24061 ctggattaat accagcagca gcagtataga ccatcaattt gccgatagcg atgtcaacac
    24121 cgttcacacc ccagtcgccc atacctaaga ttccttctgc atcagtcaca acaatcaaac
    24181 gaatgtctcg tccatctgcc gcgttcttca aacttgcttt gatgttttct ggttcgtcga
    24241 ttgaaagaaa tgcagcatct tgcggtttca agaaaatttc gttgtattgt tcgattgaat
    24301 ccgcaacgac aggatcataa acgacaggca tgaattcaac taaatgttcg cccatcaatt
    24361 tataaaacaa tgtccgattc gtattgaata gattcattaa gaagatacgt ttttccaaat
    24421 ctgtttgttt gcttaagtat tgaccataag cttgaacaga ttgttgttcc agtgtttgga
    24481 cagtacttgg aagcatacca gtgattccat attttgcccg ttcttctttt gtaaaagctg
    24541 ttcctttatt tagaaaagga ttatttaata agtttaaccc tgtaagcatg aatgattcct
    24601 cctaagtttt aatacaaacg aagtatagaa gtcagatgat gatatagtca aaaagagcag
    24661 gtatgataaa ttttatttat atgtaatata gccaaaagaa atcaaaatag cagtatttgt
    24721 tctttttata tcgacaatcc ttgcttgaat actatgcgta tctcttatat gctagagaaa
    24781 gaaaagtaga agaataaggg atagatggaa tggataaata ggatttctga ggaaaaaagc
    24841 acatgatagc gttgatagga gtcacctatg tcaggtgata aaaatacata agtagaaaat
    24901 taagaggagg aagagaaaat gaaagaagtt caattgatta gaaaaagcga actatcagaa
    24961 ggcggttgca atgcatgtgg cgtagtagaa gcgacaagct atacattaaa attagattcc
    25021 aatcaagcaa taatctctga actgacagta ggcggtcttg tggacagtct ggcgcttgct
    25081 gaaggtttta ctggagaaga tatttatgag atgttttcag aagtccgtca gttaaaaaaa
    25141 ggagaaaaat gcatagaggt tcatcatgag agcccgaatg tgaggttcaa acgtggtgat
    25201 aatgagatga tcttcaagaa tcatgtgtct gatcacactg aactatatga aatcgtgaat
    25261 caaatactgt ctgggatttt tgaattagga ccttatgagt tcaaggaaga aaacggtaat
    25321 ccaaaattaa atgaagaatg gcaagaaacg attgaaacac aaagaaacaa tccacactta
    25381 tttcaatagt cttccacagt atttcgtaaa aatgttgatg aaaaagaaac accgtgaatc
    25441 agaggtcgtg aaaaacctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagctc
    25501 ctcctatttt tcgtttggtt gggcttatta ccgcagatgc aagtttttga acaccgttta
    25561 aggaagagac tgtgaagtca acgttctgac ctgagtatta gagagacaaa tggcaaaata
    25621 gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt
    25681 ttatcgagag gttgtgaaaa agtcgcttag tttcgagtag taagaaaaat tttgtgaaaa
    25741 tggctttcca catttttgca taaatttgac ttaataccga gaaaatggct tttgaacacc
    25801 gtttattcaa aaaaagggac tttgacacta cttttgtcaa agtcccatcg gttttttatc
    25861 tatttttatt acaatcattt cttccagagt agtgacatct ggaatggctg aaatgtaaac
    25921 agattatttg cctgtatcaa tgtcgaagag taatataaaa agtgtaaacg ctatcatatt
    25981 gttcatcatt caaattttat agagagaagg cattgagatg gaaaaaacat atcaagcagg
    26041 tacaaatgaa ggaatagtag attttatcaa tatggaagat ttagaaatcg cggcttcaca
    26101 agtgattcca gctggtggtt atggttacat cagcagtggt gctggcgact tatttactta
    26161 tcaagaaaat gaacgggcat tcaatcatcg tttgattatt cctcatgtat taagagatgt
    26221 agaattaccc gatacaacta cacattttga cgaagaaatg ctgactgcac caatcatcat
    26281 ggcaccagtt gctgctcatg gattagctca tgtgaaggcg gagaaagctt ctgcaaaagg
    26341 tgtagcagat tttgggacga tctatacagc aagttcttac gcttcttgta ctttagaaga
    26401 gataagagaa gcaggcgggg agaaagcacc gcaatggttt caattttata tgagcaaaga
    26461 taatggaatc aatttggata ttcttgaagt ggccaagcgt aatggagcaa aagcaatcgt
    26521 attgacagcg gatgcaacag ttggcggaaa ccgtgaaaca gaccgcagaa acgggtttac
    26581 cttcccgctg ccaatgccga tcgttcaggc ttatcaatca ggagtaggcc aaacgatgga
    26641 tgctgtatat aaatcttcca aacaaaaact tagtccaaaa gatgtagaat ttatcgctgc
    26701 tcattctgat ttgccagtct acgtgaaagg tgttcaatca gaagaagatg tctatcgatc
    26761 attagaatct ggtgctggtg gaatttgggt atctaaccat ggtggccgtc aattagatgg
    26821 ggggcctgct gcgtttgatt cgttgcaata tgtggcagaa gcagtagata aacgtgtacc
    26881 aatcgtgttt gacagcggtg tacgacgtgg acaacatgtt ttcaaagcaa tcgcatcagg
    26941 tgccgatctt gttgctattg gcagacccgt tatttatgga ttgtctttag gaggaagtac
    27001 aggagtccat caagtgtttg atttctttaa aacagaattg gaaatggtca tgcaattagc
    27061 tggaacacaa acagtagaag atatcaaaaa aataaaattg cgtgagaatc gttttattta
    27121 agaaataaat gacgaaaaaa ataggagtgc ggcagatgat gccgtactcc tatttttata
    27181 gttcaaggat gtcactaata gaataatttg aaacgaaaaa ataaaattga aatatttttt
    27241 catacttaat aaaaaaggaa gaatattcat gtaaacgatt ttattgtttt tttctctttt
    27301 atacaaaaag ggtcataatt tcaagtaagc ggatgaattc atgaggattt tttgcatact
    27361 gtctctacta tacttaggtc actaagaaaa aggagtgatt tattatgaaa aagaacatga
    27421 ttgggacatt attactttca acacttcttc taggcggctt ggcaacacca gcttttgctg
    27481 agggtcaagc gacttcaaaa ggagatatta cctttactga accaacaaat accgttgagc
    27541 ctcttaaccc tactgatcct tcaaaaccag tagagccagc agatccggaa aatccagcaa
    27601 ctggccagac aggttcttta acattggatg tagttcctga attgccattt ggtacacacg
    27661 agattgaaag cggaacaaaa acgtatcaag tagacgcttc aaaaaacgat acaccttatc
    27721 tccaagtatc agatcgtcga ggtgtaggtg cagatggcca agcacaaggg tggaacgtga
    27781 cagtttcggt ttcagatttt gtaaacggtt cacaagtttt gcaaggcgct gaattagatt
    27841 ttggaacatc cactgttaaa agtacgtcag ataacgaatc cactggacca actagtcaaa
    27901 ctgtaactgg gttgagtaaa gcaagtgcag cgacaccaat atttacagca gcaaaagatc
    27961 aaggtctggg aacatggctt tctgtttatg atccagcaaa tatcacactg aaagtgccga
    28021 aagcagcagc tggaacattc acggctgatt tgacttggaa cctcgtggct ggcccagtag
    28081 catagagtat gaaataaatt caacaaactg cggtgaaaat actataggtg aaggattttt
    28141 taccgcagtt gttgttgaaa ggatgtggtg gacaatgaat caaagtaaac gactgtttgt
    28201 ttcgtttttt tctattttaa gtctattttt catttttccg tcaatcagcc aagcaaagga
    28261 ttcagcagga gactttggaa tcaaaccggt atttccagag aaccaaatag ataaagcaat
    28321 cggttatttt gatttattag tggcaccgga acaaaatcag acactagaag taattatcag
    28381 caattcttca gatgaagaac gaacatttga ggtctctgtc aatccggcgg taacgagtga
    28441 tggtggaacg atcgattata gtcaaaaaaa cccaacgtta gatgagacat tgccgtttga
    28501 tgtccgtgac gttttgctca ttgcgaaaaa ggaaatcaat gtatcagcac atgcagaaac
    28561 aactatacct atagaagtga aaatcccagc aaaaagcttt aagggacgtg tattagcggg
    28621 tattcatgtt tcacctaaag aagaagctga aacagaaaat gctacagaag gagcacaaat
    28681 caaaaatcgt attgcttata atctcgcagt cgttttacaa gaaagtcaag agacgataga
    28741 accggatctg aaacttttat caggagattt ggacgaggtc aacgcaaagc caactgttca
    28801 gcttcgtttc caaaatcctc agcctaggat tatcagcaat ttgatattta cgagcaagat
    28861 cttttatgaa aatcagcttt atattgaaaa tacgtctaat gaatttttag ttgcaccaaa
    28921 ttcgaatttt cacttgaatc ttgatttagc tggtgataaa gcaaaagccg gcgattaccg
    28981 cgcagaaatc atagcaaaat caggcgacag taatgaatgg cgatttacac aaaactttac
    29041 gatcaaaaaa gaaaaagcac aaaaagtaaa tgaaaattcc gtttttgcag tacaagaaca
    29101 atctttccca tggctttatg caggattggt tgctgcagtt ctagtgttat ggttgatttt
    29161 gctgtttttg tgggtccaca agaaaaagaa aaaaggagaa acaacatgat gaggtgattt
    29221 cgttgaaaac atcgatctta ttgggaggga ttattgcaag tttgctgttc ttcagctggc
    29281 aagagccagt ccaagcagat accaaaagtt caggtacgat tacattttat gatctaagtc
    29341 cagttccgca tccaagtggt tcagtcaatg gcgcatcaaa acagcagaca cagctaccga
    29401 tttataaaga atctaatcaa catggcgtat tcccggagac gaatgaagaa aagatccgtt
    29461 ttctttattt gatcattggt atagaattat ggcttcttgc gtggttgttg ttatggagaa
    29521 gaaaggaaaa ggaggatgaa catgttgcta caaaataaat tttcattttt tcgctccttc
    29581 ttttttactt cgctttttgt tttaagtata tttatctttt caccttcggc agaagctgtt
    29641 ggagcaacgc ctcctgccat ttcttatgat ccatacacgt atgaaaatat cgtacctcca
    29701 aatggtggac gtagtgcagt caatggcggg aagcttgtcc aactaactgg ggctaaccaa
    29761 ttgcctaaat tgactgctac ttatttgaac gatggttcaa atgatccttg gaaaggtggc
    29821 acggtccgtt ttcattggga aagccatgtg aaactaacaa atgtacttga tttggtgaat
    29881 atcactgcac aaggatttgc atttgtggcg atcatcaatt tgccggaaca tgtatcaagc
    29941 agtgatgtat taaaagcaat tgactggaac aacgcctact tgtatattgc cggtgccccc
    30001 atcaaggtta ctagcggtag tttattatca gcaggaagcc ataccttgcg ttttgggatg
    30061 gggtcgtggg atacaaatac tctattggca gatattattg ctattattac gcgaggcgaa
    30121 ttcaacgtgg acgatatccc gcttcaattt gatgttacag ctaatgtcgc gaagatgaca
    30181 gaaaacggag ataaatatga tacgagtcca aacaaaattt tgaccaaggg taaattacaa
    30241 ccttctatgt ctaaaaaggc cgttttttct gttgattttt atgattcgaa taatattatc
    30301 caagatcgta tgttcaattc gattttagct ccagctgcag gtagatttta tcctaaatta
    30361 actggcggaa acttgaatcc aggagcatat gcattttctg caagtgcaga gataaatacg
    30421 tggaatagtt acatctcaac aagtgattca acaggaaaat ataatacatt tgctgatacc
    30481 acagaatacg tggatggaaa taaccagaac cttccaggct ctaccaatag tcggacattg
    30541 acgatggggc tgactgaagg acgttttgat cagttgccat ttagtcgctt tgatcgcgta
    30601 gtcaactatt ttacaggaaa aaacgttaca caaggagcaa tactgactca tactccagca
    30661 agcacaagtg gattgaatca gacagccaat atcgtgtaca gtgggaaaga tgcgcaaggc
    30721 ggattgcttt ctcctgttgc tttaaaggta ttggagcagt acaagctaga cggaacggtt
    30781 ttaccaacaa acttaacagc cgatagtcag tggggaaagc tcctttcttc tgcatcgtac
    30841 caagtcacag ccaattggtc agcaactgaa ctaaaaaagg gttcgatcca ttacaggctt
    30901 tattcgaaag gaacccaaaa attagcgaca ggatggacag atcaactttt ccaaacgatc
    30961 caatcaaata acgggggtgt aaatacagct acttctacac tacctgcatt ggcttcaggg
    31021 caatattatt ttgattatcg cttggtggac gatgtactta ctaacatgta tccgtctttt
    31081 gcgtacaaat ggcagtctga acaagctgga atcaccactc ttcctcaaat aacagtggct
    31141 aattttccat ctgtgagtgc agatagtcag ctaaaaaacc ttagcagaca acctgagaca
    31201 ggagatcccc tgtctgctct atcaggagat acgattcaag aaaatgtgac attcacgtta
    31261 acaaaatctg gggatgcgat aaccgacaaa aaaatcacga tctcacttcc tgaaaatact
    31321 acttatatca atggttcctt aaaattaaat ggtacaacta tcgcagatac cggcattcaa
    31381 caaggagttt ctgtcccagc agatctattg agcaaaatag gagataccat tcatcttact
    31441 tacaactatc aattaaatac tgtagatact tctgtacaat ccgtcagcat actgacaaag
    31501 gcagctgtac tttccagcaa tattacatta gcagatggtg ctaagcttcc taacccagtt
    31561 gtccaaacat ctgctaaaac aattcttgtc cccaaacaag aattaacatt agttaatgta
    31621 ccagatgatt ttacatttgg taacgatctc cccaaaccgt tgaagacaag ttattatgaa
    31681 gcaaaaggcg atttttcttt tgatgtgcgg gatactcggc ttccaagcac gtctccttgg
    31741 caactgacag ggacattgac ttctttattt aagaatgatc aaggtcaaga attaagcgga
    31801 acaaaattat acttcaatca ttctggatca aaacaattga ttcagcaagg tcaaaacacg
    31861 ttgatttatg agagtgatgg aacagctaaa ggagaggttc tcgttgactt tcccgatacc
    31921 gatggtttac tcttagaggt aaatagcagt acgaatgctc aacctggcgc aacgtatcaa
    31981 ggcatggtca catgggaact gacagctggg ccaaccagct aagtgattag aatttgtatg
    32041 gatctgtgat aactgtcaca gatcctcttt ttcaaggatg agaaggaaac ttctgctgtt
    32101 aaaatcagaa atgcttggag gagtggactt ggaacttttc agtttgcttg aaaaaaatga
    32161 acaacggcaa atcaaacttt tccaactttt attagaggaa aaaggagaga tttccgttaa
    32221 taacgtactt acccgcttat cagttgatcg ggctaccttg aaagaagatc tgttttattt
    32281 acaagctaac ttggaaaata tcaaacaatt ggaaattgtt atccaagaag ggaatatttt
    32341 attaatcaga catggaaata tagcagcagt cgatgtttat tatcattgct acttgcgcta
    32401 ttctacaaaa tatcagatac ttctttatct gttggaaaat ggctcatttg atcggcagaa
    32461 acttgtcatg gaacttaata tcagttcggc tactttgtct cgcagagtga aggaattaaa
    32521 tgattcttta aatgagtttc atctgaaaat aaaaagcggg cggctgaccg gtccagaaag
    32581 tcaaatttgt tatttttatt tccaattatt ttggtttgga cgtccttatc ttgaaaacaa
    32641 aaaagaatac agtgatttat caggaaacac ttttttagat ctgctgcaaa aagagtttag
    32701 ttttactatt acagaagaag gacgattgaa atttgaaata tggctttcca ttatgaagaa
    32761 gcgaatgcgc tgtacgaaaa aatccaaacc agattatagc aatcttcctg ttggattgtt
    32821 tcaaacgaca caatttttat tggacctcca tacatttttg acccgttact tctttcaata
    32881 tgcctttcct tggaatcaaa atgaaacgtt ggttttttat cttttcatga tcagtaactt
    32941 tacattagat acacataact cgcatgtcca ggagtttttg ataagcgaaa aatacaaaga
    33001 cgacgtagta gctcaattga atcgaacgtt taaacaatcg atagaagaat atttctcttt
    33061 ttatgttttt ccagaagaga tttcgcaaaa gattgcgttg acagtgatgc aaaatcacgc
    33121 tcattttgcc tattttagag gatggatgaa tatttttggc caagaaggat taaaacagcg
    33181 gttaactgaa gtagaagata aacaattcct ggttttatgt gaaagattgg tcagacaaac
    33241 atttgctatt gttgatttta ctgaagtaga cgaggaaaat gcccgctttg aattatttgc
    33301 tcgctatgca tctattttgc ggacgctgat caagcagtta gaattacgtc tgcaaattgc
    33361 ttatgatctt ccttatgaaa ggctaatggc ggatatcgtg aaagaaatca tccaggaaca
    33421 attgctgaat acgatcaaat atgatttagt cgaatacgag aaagaaaagc agtatgatat
    33481 cattttgact agccaattga aagagtaccc gtcacagaag tccgctaaag tttttgtatt
    33541 cactagcaac gaatataatt atgatttccc ctatttgaac caatttttaa aagaatgtta
    33601 tttagaaaaa ttgaatttaa ggatgaataa aacatgaaaa tcgtgatcat tggtgcttcc
    33661 catgcaggca tcacagctgc cctaaatcta agaaaacttc aaccgaaagc agaagtttta
    33721 ctgatcgatg aagatcataa agatggacta ggctatgttt caaatggaat caacctttat
    33781 ttaaaaggaa agatacgtag tttagctgaa gttgcccata acatgcggac tcttcaagaa
    33841 agtggggcaa aactgatcac cgaatggaga gtaactgaac ttgatccaga caaacatcag
    33901 ctcatcctcg catccaaaga aggaaaaaac gagaccataa cctatgataa attaatcgta
    33961 gcaacaggtt cctctcctgt caccttgtat aaacaaattg aagctgaaaa tgtctacacc
    34021 tataaaaatc tagtgcaatc taagcaagta cttgccgctt taaaagaagc aaaagaagta
    34081 gtgatcttcg gtgctggtta tattggattg gaattagcag atgctttgag aaataaagga
    34141 tacattattc atctagttga ttatatgccg aatgttttat caagatattt cgataaggat
    34201 atgatcaaca gttttcaaaa tcagctgcaa actaagcaaa tcaattttta tccaaatgaa
    34261 ttcttgatcg attggaaaaa atcagaagag aaagtagtat ccgtacaact tctatctcaa
    34321 gcaataaagg cagatatggt cattttttct gcccaaactc gtcctaatac gacattgtta
    34381 aaagaaaaag tggctttgta tgaggatgag actgtgatag tcaatgaata tctgcagaca
    34441 agtgatccgg acatctatgc gattggagat atcgtcccag tcagttttga caaaaataaa
    34501 cggcatctct ttttaccttt agttactcga gctgtacata tggcaagagc agtagcgcta
    34561 actttgagtg gtcagccaac cgcttacgac ctcagacaaa agataacagc agcagtcatt
    34621 atagactact ttttaggaac tgtagggctg acagaagatg aagcgccatt cttggaacaa
    34681 aataccggtt cgtgttcagg agaatttgat ctatttccac aatacgatga agaaaacaaa
    34741 acagtaaatg caaagctgat ctaccatccg gatacattag aaataattgg cggacagctg
    34801 ataagccaag aattcttatt atcagatttg aacctgcttg cggatatcgt gaaacacaaa
    34861 actacgattc cacagctagc agttgaggat tttggatttc tgtctgaaca cacctctcgt
    34921 tttcactacc tcaatgagtt agcttttaaa gtactagcta agagagcaaa tagcaataga
    34981 gtagataaaa gactgtgaga aatatcacgg tcttttattg tgtggggata taataaatat
    35041 taatcaatcg agaataaaaa attcatataa tgaaatagcg gaagaatttt ttgagcataa
    35101 tattcgccaa aaatttatca agtgataaaa ttgttgtata aaatgattat ttcaggagga
    35161 ggagttaaat gtttttagca ttaaatgaaa ttatgcattc aaagttacgt tatgcgttag
    35221 ttgcaggggt gatgtttttg atcgcctacc tggtattttt tttgactggg ttagcttatg
    35281 gcttagctca agataatcga acagcagtcg acaagtggga ggcagattcg attgtgcttt
    35341 cgaaagatgc aaattcaaat ctagggatgt ccatgattac taagaagata gcagaagaag
    35401 tcgaaggtgg gaaagtggcg tatcttgccc agacacctgg agtcgtgact agtaaagaca
    35461 gtacagaaga aggaaaaatc aatgttagct tcttcggtat cgataaaaat caattcatca
    35521 tgcccaatct tgttgaagga aaagcttttg ataacgatga tgaggcagta ggcgatatta
    35581 gtttgaaaga agaatatggt ctagccgtag gagatacagt taagttatct ggtagtgaca
    35641 agacgtttaa actaactggc tttacggatc atgccaaatt caatgtctca ccagttctct
    35701 atacaaccat caatgcttac caagagatcc gcttcgaaaa agaagataca agtgaaaatg
    35761 cacggattaa cgcaatagtt gtcagaggta aaatcagtaa tttacctgaa gatttagaac
    35821 agatcaaaat ttctaaattc atcaatgaat tacctggata taatgcgcaa gtattgactt
    35881 ttggatttat gatcggattt ttgatcgtta ttgcggctat tgtgatcggg attttcattt
    35941 atgtactgac gatgcaaaag attaatatct ttggtgtaat gaaagcacaa gggatcacag
    36001 gaggatttat tgcgcgttct gtagtggcac aaacattcat tttatcattt gttggtattc
    36061 ttcttggtct attaggaaca gtgggaacat cccttgttct acctgatgcg gttccattcc
    36121 aaagcaattg gctgtttttt ggcgtcatta gcttgttgat gctggtagta gctgtgttag
    36181 gcgcactatt ttctgttcgg acaatcgtaa aaatcgatcc gttgaaggca attggataag
    36241 aaggaggaag agcatgaaag caatagaatt taaagaagta gaaaaaagtt tccaagatgg
    36301 cgaccaagta gttaaagcat tgaaagaaac aaccatgagt atcgataaag gggaatttgt
    36361 tgcaatcatc ggtccttctg gttcaggtaa aagtactttt ttgactttgg caggcggatt
    36421 gcagacgcct agcagtggct ctgtatttat caatgatcaa gaattcagta atcaaaaaga
    36481 aagtgaacgc gttaaactac gttttaaaga aattggcttt attttgcaag cttccaatct
    36541 ggttcctttt ctgacagtaa aaaagcagtt attattagta gataagatca aacatgaaca
    36601 tcgtcaaaaa gaagcaaaag aattatttga gcagcttggc gtggataagt tgatcaacaa
    36661 gtatccagaa gaactatctg gtggagaacg gcaaagggtc gcaatcgctc gtgcattgta
    36721 caatgatccg tccattattc tagcagatga accaactgct agtttggatt cagaaaaggc
    36781 acgagaagta gtcgatatct tggcaaaaga atcaaaagac aaaaataaag caacgatcat
    36841 ggttactcac gatacacggc tgattgacaa atgcgataga atatttatga tggaagatgg
    36901 tgtattgaaa gaaaaagaat aaccaaaaag caggtggaaa aatggtccat cgatacaaca
    36961 aagatacaca gcaaaaaatt ttgaaagaag cgactgactt gtttatgtcc aagggatatc
    37021 tcggcacttc aacaagagag atcgcacaaa aagttgggat cacccaaccc aatctctatc
    37081 attatttcgg tgataaagaa aaactatata cggcagtttt agaaaaccac ttaaaagatg
    37141 ttggaaaagc tttgagagaa atcgttcaaa caagcgaaac gggatttcaa gtaaccttga
    37201 caaaaatggc gcagtttttg attgagacac atctggtcga tttgtttctg atgcttcacg
    37261 atcttgaaag caatctttca aaggaaacaa gagatcatct tttctttcta tggaagaaaa
    37321 attatcgtga accttttgaa gaaatctttt cagcaaacca atctgtgcta agaaatggga
    37381 tttcaaaaga aatcgcagca aggcattttt tcttagtgtt agcaccttac atcactcggt
    37441 cgaaaagacc tgtggaagaa ccgctaaatg tggcgcaatt gatcgattta tatttgaatg
    37501 gtgtattagg agaagcgtaa agctgttata tagggagaaa aatagttagg tgaagaagca
    37561 agatatgacg aagatcgtta tatcttgttt tttttatata ggtagttttt cataaataca
    37621 aatttgttat tctctcatga ttatcagggt atatttttat ttattatgtc ggtgttccag
    37681 gaagtgtttt aatttaataa cgaagaaatt aattgtttgt agaatgaagg aaactattta
    37741 ttgggtagat gaatcaccac gaatagtcaa aaggagattt caggatatgc caaaaatgaa
    37801 aaaaatcatt ttagcagtaa tgttattttc tacggttata tcttttacag cccctttttt
    37861 gcgtacttaa gctgatttta agttttgacc cttagtctgg atctacgagg tgagagtcaa
    37921 gaatgaaaaa aataattgga gcttttgtat ttgcaatcat tatcattatt atctgttttc
    37981 aaatagatgt ttttggtcaa aaaaagatag ttggacaaac ggtcagcagt acgaacagta
    38041 cggttacaaa gacaaaggaa tcatttgatg atacagaaca agagacatta atcaaaatcg
    38101 gaaaaaatga ccgtacacta tatacagatg actcgctaac taccccactt gcaactataa
    38161 acggcggaga gctggcggag tttctttctg aaacaaaaaa tgcttatcag atcaagacaa
    38221 atgatggcta tactggatat ttagccctcg aagatggaac caaagtcaca aagaatatac
    38281 aaacaaaacc ggaagagcta tctgatgcag tgattgtatt agatcctggg catggcggaa
    38341 atgatactgg ggcattaagc aatgatgaac aaacagaaga aaaagatata acattaagta
    38401 cagccataaa agtaaaaaag gcgctagagg atgctggagc aacggtttat ttgacccata
    38461 ctacagatga attagtacag cttggagata tatgcgacta cagtgaagaa aaaaaggcag
    38521 atgtctttat cagtttacac gcagactcta cggaatatgc gaatgaagca actggaatca
    38581 cgacatatta ttactatgga caagaggaaa cattagcaca gacaattgct gactccttca
    38641 ctgatctgcc tctggattca agaggaatct ccactgggaa ctatcaagtt cttcgagaaa
    38701 atcttcaacc ttctatttta atcgagatgg gttatatgaa taatgatagt gatttaaagg
    38761 aattagtaac agacagttat cagcagcaga ttgctgcaag tttgacacaa gcattgacca
    38821 cttattttca gtaataaata agcccagcca aacaaaaata gctcctcata tttttcgttt
    38881 ggccgggctt attatcgcag atgcaagctt ttgaacaccg tttaaggaag aggttgtgag
    38941 cctgccgttt aactccgcgt cacaaggagc aatttcaaaa aacagcttct catgtttgat
    39001 gactattgtg acttgtgacc gaggagttgg catgagaaca ccgtttattc ggaacaaggg
    39061 actgtgacat gacttttgtc acagttccat tattttttta gcagcttcaa agctttttct
    39121 gtattggcaa aatgaagttt ggcatatttt tcaagcatag gcatgccgcc tttctccaat
    39181 agttttgccg ctacttggtc agatttcgtt ccagctcctg atggaagggt gattccagct
    39241 tcagctgatg ctttgtgtaa ctcttccaaa aagctggcac gactgatgat agaagcagca
    39301 gcaacagcta aatgatattg ttctccttta gtaacgaagt acagtttttc ttgtaattga
    39361 tttttttcta aacgcgcata ttttttaaaa tttgcttccg gcgtaaactg atcgatcaaa
    39421 atcgcttctg gtttttctgg ctcgattttt tttagcagca aatggatcgc ttgattgtgc
    39481 aaagcgactt tcatccgaac ggcattgtat tttggttgga tctcattgta tttttctgga
    39541 gataagacaa gcagtttata ggggatggtt ttttttaaga tgtcagcaag ctggatgatt
    39601 tggctatctt ttaactcttt tgaatctcta acaccaagtt tacgtaattc tgcaagctga
    39661 tcacgtttca cataagcagc acatactgtt agcggaccaa aatagctgcc atttccgacc
    39721 tcatcactac ctaaaacgga taattgactg atattttttg gcaaagaaga ggctgttttt
    39781 gctggcttgg cttgtttatc ctgtgcctcc ccccatttat cagcttctat tgctgcattc
    39841 gtaccttgaa acatcacttt tccggatgta taagcggtaa tggtcgtccc gtcttttttt
    39901 gcagcaaagc tagtataagg aatctgttta tttaacaaat aagagcgata gtatgctttc
    39961 atttgactaa gttggtcgtt tgttgctttg ataatgacgt tgctcataaa attctcctcg
    40021 tttttataca taaaactata ccgcaactca cgacttttcg ttttctaaga gattgcgaga
    40081 catagcattt ttttaaagtt tatcatataa tagttaagta tgtgaaaaat atttgtggag
    40141 aacggtgaaa gaaccaactt catggtacac taaataaaac tttcatcaaa taggaggaaa
    40201 tgattcgtat ggcgcacgaa aaaacacgct acaaagcagt gattgccaac caaacatata
    40261 ctattatcgg acgggaaacc aagcatcata tggatatcgt aacgaagctg atcaatgaac
    40321 agttagcaga attgaaacaa ttatcaccac aaatggataa tgaacaagca gcaatcttga
    40381 tggctgtcaa tgcgctttcg gatcaattga agaaacaaga aagaatcttg gagctggaag
    40441 aagaaacagc agaattaaag aaaaaaatga tcaaatttac agagcttgaa aatcgtgtga
    40501 aacgcattga agcaatcgag aacgaagctc gggaagtatt gaaagaaaat ggtcaagcag
    40561 atcataccat taaaaatcat gtggaagcac aacagatttt aaacgagaaa cgaaaaggac
    40621 aaattaaaca aaaatcttct aattaagatc cttttatcaa aataagaaaa atttaaaaaa
    40681 gttagaagag aaaggaacgt agcatgctga gtttgctgat tttattttta ttgctaattg
    40741 cgtttttttc tggagcacgt cgcgggtttg ctttgcaaat catattcgcg attggatatg
    40801 tattgtcatt tattgctgcc cagcattttt acaaaccatt agcaagtcat ttggaattat
    40861 acattccata cccagctgtc accccaacat caaagttagc attttttgat caggtatttg
    40921 cttttcacct agatgaagct ttttatgcag gaactgcttt tctgattatt ttgctaattg
    40981 gctggctgct tacccgattt gtgggggttt ttgtccatgg attgacgtat gtgccgatct
    41041 tgagacaggt agactggatt gcaggaggca tcctgtcact aatcatggct tacgttacta
    41101 tatttttgat tttgcagtta cttgcctttg ttccattaga tgtggtccaa aatcaattcg
    41161 gcgagcatag tttcgctcgt tttatcgttg agagaacgcc atttcttacc aacaagatgt
    41221 atgagctttg gtaacgaata ttttgaatta aggaaaatag tgctggaaaa tatttcgttt
    41281 tttgtacaga gtagtttatt taagaaggct gcgtagcgta tgtccggcac agctcttttt
    41341 tcatagtgaa agataaggtg ataaaatgaa taaccgaatc cttgaaacat tggaatttga
    41401 aaaagtcaaa cagatggtca gacaatttgt agtgactgca caaggaaaag aagaactggc
    41461 agaattggta ccagtgagtg agaaacaaac gatcacaaac tggcttcaag aaactgagga
    41521 tggattgaaa gtgcaacgtc tgcgaggcgg gatccctata cctaaacttg aaaatatccg
    41581 tccccatatg aaacggatcg agatcggagc agacttgaat ggagtggagc ttgcacaagt
    41641 ttccagagta ttgtctacga caagcgaatt gaatcgtttc attgatgatc tttctgacag
    41701 tgaaatcgaa tttgcacgtt tgtatatgtg ggcagatcag ttagtcacga tccctgtttt
    41761 gagccgccgt ttaaaggaag caatcgatga agacggacgc gtgactgatg acgcttctcc
    41821 tgagttaaag agcataagac agaacattcg gcgaagtgaa caagctgttc gtgaacagtt
    41881 agatgggatc gtccgtggga aaaatgcaaa gtatttaagt gatgcgatca tcaccatgcg
    41941 aaatgaccgc tacgttatcc cagtcaaaca agaataccgc ggtgtatttg gcggtgtagt
    42001 ccacgatcaa agtgcttcag gacagacttt atttattgaa ccaaaacaag tggtggattt
    42061 gaataatcgt ttgcgtcaat accaaatcgc tgaacgaaat gagattcaac gtattttaag
    42121 tgaactttct gctgaacttg ttccccatcg tcaagaaatc atccacaatg cttatgtgat
    42181 tggtaaaatg gatctgatga atgcaaaagc acgatttggt aaagaagtaa aagccatcgt
    42241 gccgggaatc agtgaagaca atcatgtcgt cttgaaacaa gcaagacatc cactgatcga
    42301 tcaggaaaaa gtagtttcta atgacatcac aatcggaaaa gactatcaag ccatcgtcat
    42361 tacaggacct aacacaggtg ggaaaacgat cacgttgaag actttaggtc tgttacaact
    42421 gatggggcaa gcaggattac cgattcctgc aggtgaagaa agtcaaatcg gtatttttga
    42481 ggaagtattt gcggatatag gagacgaaca gtcgattgag caaagtctat cgaccttttc
    42541 ttctcatatg acgaacactg tagatatttt atcaaaagtc aatgaaaaaa gtctggtatt
    42601 atttgacgag ctcggtgcag gaacagatcc gcaagaaggt gctgctctag caatcgcaat
    42661 cttagatgat cttggtaaaa agtctgctta tgtgatggca acaacgcatt atcctgaatt
    42721 gaaagtttat ggatacaatc gggcaaatac gattaatgcc agcatggagt tcgatgtgga
    42781 tacactaagt ccaacgtatc gtttgctgat tggcgttcct ggacgaagca atgcgtttga
    42841 aatctctagc cgattaggtc ttgatacaga agttattgat gaagcgaagc agttgatgaa
    42901 tgatgagagc caagatttaa acgaaatgat cacagattta gagaatcgcc ggaaaatggc
    42961 agagaccgaa tatctggaaa tgcgtcattt tgtttctgag gcacaagaac ttcacgatga
    43021 tttgaaagaa gcttacagct atttctttga agaacgtgaa aaagaaatgg aaaaagcaaa
    43081 gaaaaaagca aacgaagtcg tgtcagaggc ggaagaaaaa gcagaaaaaa tcattgctga
    43141 tattcgtaaa atgcaacagc agattgggca aggaaatgtg aaagagcatc agttgatcga
    43201 tgcaaagacc caattagcaa atctacatca agaagaaact ttgaagaaaa ataaagtatt
    43261 gaagaaggcg aaagaacaaa aaacgttgaa accgggagac gaagtgttgg ttacgactta
    43321 cggccaaaga gggacgcttt tacgtaaaaa cgggaatcag tggcaagtag aaatcggtat
    43381 attaaaaatg aatgtgtccg aagacgagct gacgcctgtt gctcctcaaa aagagccgac
    43441 acaacgagtt atccatgctg tacgatctga atctagtagt cacgtgccga atcaattgga
    43501 ccttcgagga aaacgatacg aagaagcgct aagtgaggta gatcaatatt tggattctgc
    43561 cattctagct ggttatcctc aagtgactat tgtccacgga aaaggaacag gcgcacttcg
    43621 caagggaatt actgattatc ttaaaaacca tcggagcgtc aaaagctttg agtttgcacc
    43681 ggcaaaccaa ggcggaaatg gtgcgacaat tgttaaattt aagtaaagct tactaaaggt
    43741 aagcagatgg ttcgctatcc aagtatagaa atgctatact aatcatagat tttaaaaatg
    43801 gaggtctttg atatgtcaca agtaattaca gataagacat ttaatgaaga aacagataaa
    43861 ggacttgtat tgattgattt ttgggcaact tggtgtggtc catgtcgtat gcaagcaccg
    43921 attttggatc agttggaaca agaatatgat gaagaagaat tcagaattgc taaaatggat
    43981 gtggatgaaa atccagaaac tcctcaacaa ttcggtatca tgagcattcc aacattaatg
    44041 ttgaaaaaag atggtcaagt agtagaaaaa gctgttggtg ttcattcaaa agaacaacta
    44101 cgtcaaatga tcgatcaata tttataaaaa cttacagcaa aaataagctg agggtgggac
    44161 tgaatccagt tccgtcctcg gtttttttgc ggttgagtta aggttattca aattaatatt
    44221 ttttgagtat aattacgttg tcaggctgga ttgttttttt gacagacatg ctataataac
    44281 tttaattgaa tatgaagggg agtaccagat gaacgaacga atcaaaaaca aattagcttt
    44341 acttcctgat cagcccggct gttacttgat gaaagataaa aatggaacga tcatttatgt
    44401 cggcaaagcc aaaatattaa aaaatcgtgt ccgctcatat tttactggca gccataatac
    44461 gaaaacggaa cggcttgtta gtgaaatcga agactttgaa tacatcgtta cagaatcgaa
    44521 tatcgaagca ttgctcttag agatcaatct gataaagaaa aatgatccta aatacaacat
    44581 tatgttaaag gatgataaaa cctatccttt ccttaagata acgaatgaaa aatatccccg
    44641 tttggtgatt actcgtaaag tactaaaaga caaagcactg tattttggac catatcccga
    44701 tgtcggtgcg gcgaatgaga caaagaagat cctcgatcga ttatttcctc tgagaaaatg
    44761 caaacctagt cagacgaagg agccttgtct ttactatcat ttgggacaat gtctgtgtcc
    44821 ttattatttc gacgtagatc cgaaagtcta tacgaaaatc gttgatgaag tgaaaaagtt
    44881 tttaaacgga ggacacgaaa aaatcgagtc agagatccat cagaaaatgg aaaaagctgc
    44941 tgaaaacatg gagtttgaaa aagctgcaga ataccgagac cagatccgtg ccattgagac
    45001 aatcatgact cgccaaaaaa tgacaaatac tgatttactg gatcgagatg tatttggtta
    45061 tgcgattgac aaaggatgga tgtgtgtcca agtgtttttc gtaagacaag gaaagctaat
    45121 tgaacgagat gtttcaatgt ttcctttcta taacgaagca gaagaagatt tcttgactta
    45181 cctcggtcag ttttatcagg aaaatgagca tttcattcct aaagaagtct tgattcctga
    45241 tacgatcgac aagcccagtg tagaagcttt gttagctacg aaagtgctgc aaccaaaacg
    45301 aggagaaaag aaaaaattag ttgaattggc gaataagaat gcctcagttg ctttgaatga
    45361 acggtttgat ctgattgcca gaaaacagga acggacgatc ggagcagttg aacgtttagg
    45421 aaacgcgatg aatatcccga ccccaatacg tatcgagtct tttgataact ctaatatcat
    45481 ggggacgaat cctgtggctg cgatggtcgt attcattgat ggaaaaccgg caagaaaaga
    45541 atatcggaaa tataaaataa aaacagtcaa cggaccggat gattatgcat caatgagaga
    45601 agtcatctat cgcagatatt cacgagtgat gcctttacct gatttgatct tgatcgatgg
    45661 aggaaaagga caagtagatg tggcaaaaga tgtcttagaa aatcaattag gaatcgatat
    45721 tcctattgct ggcatggcaa aaaacgataa acataaaaca aatgagttgc tattcggtat
    45781 agatttggct gtagtaccgc ttgagcgaaa ttcaccagag tttttcttac tccagcgaat
    45841 ccaagatgaa gtccatcgat tcgcaatcac tttccatcgg cagctacgca gtaaaaacag
    45901 ttttgcttcc cgattagatg aaattgaagg gttaggacca aaacgaaaaa aaatgctgct
    45961 taaagagttc aaatcgttga aaaatatcac agcagccacg acagaagaat tacaagaaat
    46021 cggactgccg aaaaatgtcg cacaaaacgt atttgataaa ttacatcagg aatgaggaaa
    46081 gggcacttta caaagaaagt aaagtgtcct atcattttat gtacaacaaa aagagcgttt
    46141 acgttttgtt ggtaaataat aaatcgctta cgtctggtgt ctaaggatat atgtgatttc
    46201 ttgaagaagg agtgaagaaa tgttagaagt caaggatctt gttaaaactt ttgggaacta
    46261 cacagctgtc gatcatgtct ctttccaaat ccccgatgga aaaatcatgg ggctaattgg
    46321 ccaaaacggg gctgggaaga caacgacttt tcgtttgatc ttggattttt tgacacaaga
    46381 ccaaggagaa gtgttatgga atggccatca tcttggggag aaagattatg atgtcatcgg
    46441 ttatcttccg gaggaacggg gactttatcc gaaagtaacg attcaagacc aactgcttta
    46501 ttttgcagaa cttagaggga aatcaagaaa agagattgaa ccaaaaatcg atttttggat
    46561 ggaaaaattt caggtaaaag ggaaaaagac ggataaagta aaatctttgt ctaaaggaaa
    46621 tcagcaaaaa gtccagctga tcgccacgtt aatccatgaa cctaaattga tcattttgga
    46681 tgagccattc agcgggttag atccggtaaa tgctgaattg ctaaaagatg gaatattgga
    46741 attgaaaaaa catggttcat gtgtcatttt ttctagccac aatatggata atgtagaaaa
    46801 aatctgcgat catttgatca tgttgcgaaa cggaaaaatg gttttgaatg gaaaagtaca
    46861 tgagattcgt gaatcatttg gccgtacgaa gttattcttg gaatctggtt taagccaaca
    46921 ggaagtagaa gaaatcgaag gcgtgaaaaa agtgatcctt catgaagaca atacgttaga
    46981 gattacctta gaagatcctg aagctgggaa agaaatcttt actcgtgcga ctcagttcgg
    47041 ctacattcct atgtttaacc agcaaccgcc aactttggaa gagattttca aattgaaagc
    47101 aggtgaaatc gatgcgtaag ttttggatta ttaccaaaga tgtctattta aaaaatgtta
    47161 agtcgatttc tttcttgatc atgatattag tcccttttat catgctgggt atcatttatg
    47221 tagcaggaaa ctttgctcaa caaaatagtg atgtcaataa aatcggcgta ttggctgata
    47281 atgagcaaat cagtcagcaa atgagccaag tcaaaacaga tgattttgag ttcaaagcag
    47341 ttgattctga agaaaaagca caaaaagagc tttcggaaga aaaaatcgat gcgtatttag
    47401 tagtctcaac tgagaatgat aagataaatg ggatgcttta tagcgaaaat tcattaggac
    47461 aaagtacaca actactgata caacaacaac tgactggctt gcaatcgatg cttcgagcaa
    47521 gtcaattagg catttcacca gaagaagtag ctagcttgag ccaacaagca agtttgactc
    47581 gacaaaaagt caattttgat tcaaaaggaa aaatgacagt tggagaagat aactcgacag
    47641 tccaatatgt cgtaagttat gtagcaacga ttgtcttgtt cattattatt ttgacgtatg
    47701 cgcagatcat tgcacaagag atcgcttctg aaaaaggcac gcggatcatg gaagtgatcc
    47761 tgtccagtac gactgcacaa aagcattttt acggaaaact aacaggtgtt ttacttgttg
    47821 cattaacgca aatggcatta tacggtatta tttttggtat aggatacagt caattcaaag
    47881 atatggaaat ggtcaaaaat atattagacg gtatctcatt ggataacttg attggaccat
    47941 tcttgtggta ttctcttcta ttcatgatct ttggcatttt gattttttct gttttagcag
    48001 ctttatgtgg ctctttggtc aacaaagcag aagatacagc aaaagcaatt ttgccagtga
    48061 cttatctatc tctaggcgga tatatgcttg gattgatact aggagcttca gatccaaaca
    48121 atatcgttat tcggatcact tcgtatattc cattcttatc ttcatatatt atgccggttc
    48181 gcttagcaaa tgagacagtc ggtatgggtg gagcattgat ttccttgttg gtacttgtag
    48241 ccgtaacatt cttattgatg atcttgtctg caaacatgta caaatcgaat gtactcgtgt
    48301 atagcgaagg cggattatgg agttcattga aacaatcgat ttcaattatg agaaatgaac
    48361 gaaaaaaagc ataaaatata gaaaaatata gaaggaagct ggacatttat tgttcccagc
    48421 ttcttttttg tatagaccta tttctatttt tttattatat tggatatata tattcattga
    48481 aaatagagca taacaacttt ataatgttga gtataccaat ttttggaggc gttttaatgg
    48541 accgctattt agatttactt tcagagaagt tccctacaac ggaagatgtc atcacggaaa
    48601 tcatcaatct cgaagcaatt ttgcagcttc caaaaggaac agagttattt ttgagcgata
    48661 tacatggcga atttcctgct tttgatcata ttctgcgtat cggttcagga aatcttaaag
    48721 aaaagatcaa agaccttttc tctgaacaaa tgacggaaac ggagatcagc caattcacta
    48781 tttttacggc ttatccagaa tatgtgttga cgactgattg gtacaaaaaa caagataaat
    48841 cccagctgat ccatcgtttg atcgatcttt tacggtttac gacagtcaaa tacactcgat
    48901 caaaagttcg aaaaggattg ccgaaagaat atagctatat cattgaggaa ctcttgtata
    48961 tcgatgatcg tatcaacggg aaaaaagact atgtaaaaaa aatcattgaa caacttgtct
    49021 tgatgaagga agaagaaaaa tttttaacaa aacttgcgca gacgatccaa aaatctgtca
    49081 tcgatcattt gcatatcgtg ggtgatattt ttgatcgagg aactcaagca gccaaagtaa
    49141 tggatcgaat catggatttt tcctctgtag atatccagtg ggggaatcat gatattttgt
    49201 ggattggtgc gtattgcggc tctgaggcat gtttattgac gcttttacgg attgccgcac
    49261 gctacaacta tttatttgaa ttagagaaag aatatggatt aaatttacgt ccattatttt
    49321 cttttgccca tcaaacctat cagaagaatc cagtatttac ccctaaaaac aggaaagatc
    49381 tatctgaaag agagcaagaa gaattagaaa agatccatca agcactttct atcctccaat
    49441 tcaaatcaga acatcagttg ttgaatcgac gacctgaatt taaaatggac gatcgtaaat
    49501 tgttggaaaa aatcaactat gaggaatcaa cgatcgtttt agaaggtcag ctctatgagt
    49561 tgaaagggac ttgttttcaa acgatccagc cagatgatcc taaaaaattc ttggaagagg
    49621 aacaaaaagt gatcgatagt ttgatgtatt cattccagca ctcgttaaga atgcaaaaac
    49681 acatgacgtt tttgatcgaa aaagggggaa tgtatctcac gaacaatcag catgtactgt
    49741 tccatggctg tatacctgta gatgaaaagg ggcagctctt agcatttgaa ttagaccaat
    49801 cttatcgcgg aaaagaactg ctgggatttt ttgaaaaaca gataactgaa agcgcaaaag
    49861 atttgactgc aaatgaagat ttggcgaccg atttgatttg gtatgcgtgg agcgggccat
    49921 tttcgccttt attcggcaag agtaaaatgg caacttttga gcgctatttt ctcacagagc
    49981 ctcatacgca cgtcgaaaaa agcaatccct attatcactt gcgagatgaa gagtggttca
    50041 gtgaaaaaat tttggcagaa ttcgatgcaa aagaagaagg ttcagcaatc atcaatggac
    50101 acacgccagt aaaagtaaaa aaaggagagt caccgatcaa agcaaacgga aaagcatttg
    50161 ttattgacgg aggtctatcc aaagcttatc aaaaaacaac cgggattgct ggctactcat
    50221 tactatgcaa ttcttacggt ttccaaatcg tgacacatta tccgttcttg cctattgaac
    50281 aacaatttgc aaaaaaatct gatcaaacga atgtaaaaaa agtgatcgag cagcagctcc
    50341 cacgcaaact taatcggaat acgacaaaag gaatggaatt acagcaacag attactcaac
    50401 tccaaaggct gttggattat cgaaaggacg attgagaaaa atgctagcca acattgctca
    50461 atagactaaa aagcgactgc aacaaaaggc gtgtcgcagt ctccttcgga attagctcaa
    50521 aaaacggtaa aatattagaa gctatttttc tgtttatttc tctaatactc aggtcagggc
    50581 gctgatttca cgacctcttc cttaaacggt gttctcctgc caactcctcg gtcacaagtc
    50641 acaatatcca acaaacatga gaagctgttt tttgaaattg ctccttgtga ctcagagttg
    50701 aacggcaggc tcacgaccta atcagaaaaa cgattaaaat tcattcacaa agaaatcgaa
    50761 taaacgctgt tcagatgaat ctacacgatg agaaagttcc ggatgccatt ggacaccaag
    50821 gattttgtgc atattatctt tactttggac tgcttcaatg agtccatcgt tggaaaaggc
    50881 gatggctttt aacaaaggag aaagatcttt gactgcctga tgatgatagg aattcacaaa
    50941 gtatgaatca gggagaaggt cacttaataa actgtccgaa acgattttga cttcgtgagt
    51001 tgcaaactgc ggggcagtgg gctgttgttc gtgttttacg gaccattttg gatataatga
    51061 aagatcttga taaagtgttc cctccaacac gacattcaat agttgaagtc ctcggcagac
    51121 tgcaaaaatc ggttttcttt gtttcaatgc ttccaagatc aatgcctgtt cgaattggtc
    51181 tcgttgaata tttgtttccg tcagttttgg atgagggtct tccatgtaaa gttgcggact
    51241 aacatcctga ccgcctgcaa gaatgagttt gtcgattttc tcaattagtt gaggcgctga
    51301 atctggagac atgactggca gaataagagg taatccttga gcatctaaaa ctgcatccac
    51361 aaatccctgc ggtgtatagc ttacttgatt tccttggaaa gtatctgtcg ctcgaatcag
    51421 ttgattcccg gcaatgccga tgattggttt catttttatt ccccctaaag tagactaatt
    51481 gtaacaagga tttaaaaaaa tttaaactat gtaagacttg cccctatact tatctgttct
    51541 tgctgtgtta ctatctgtaa agagaatttt cgtgtgaaat tcatgacgat agttgaaaat
    51601 attgcttaat ttgttataat aaaaagtaag cagaaataaa aaggttgggc gtaagcttca
    51661 aggatctagt tcttcaaggg gtgagaagga cattttattg aaggggcctg cctatactaa
    51721 gttatcttta gaggtacata ctttcaatga aaaaagaaag catgtacctc ttttttaaat
    51781 cgaaaggaag tgaagcaagt gttagaagct ttggaacaaa tccgaaaagc agaagaagaa
    51841 aatgagaagc gtgctcgaac cctacggcag cagttgaaga cctatgcaga agaaaaagag
    51901 caagaattgg agataatcca aacgaacagt cggcaacagc tgaaacagtt ggtagaagaa
    51961 aaagaacaat tcgaaaagca agaattagaa aaagaaaaaa tgaaattgaa agcagaagca
    52021 gacaaggtgc aagcaacttt gaaagaccaa tatcaaaagc atcagagtca agcaatcggt
    52081 gcaatcattg aaagggtgaa agaaacttat ggccgtcact aagatggaaa aagtgaccct
    52141 catttcagat aaaagaaatc aggagaggat tttacaagca gtacaaggaa tccaaaatgt
    52201 tgaaatccgg gatctgtatc aaaatagaac aaacaaccag tgggtagaaa aatattttcc
    52261 agataccacg attattgata aagaagcaaa attaagcgct ttaggcaatc ggctgaaaga
    52321 catccaagaa gctatccaat tcatacaaca ccacggcgat agccgtcaaa agaaactcca
    52381 tttgaaacgt caagaacttt ccttacaaga cttggaagca aattattccg aagaaaattt
    52441 catgaataaa ttagaagaag tccttgattt aaaagaaaag tgggaacagc taactgaaaa
    52501 acgtgatcgt ttagaagaag aggaagaatg gcttcttcat tggcaacagc tggatattgc
    52561 tccaagtatg tatgcaagta agacgaccat ttttgagatg gggactgtga gtgcagcaaa
    52621 ttttgaaagt ttcaaggaag aactaagtaa gcttgatgac gtttatatgg aagaaataga
    52681 ttatacgcca aaacaagttt atctttcgta tgttgcttta aaaaaatcag ttgctgctat
    52741 agaagaaatt gctgggaaat acgggttcaa taaagaaacg tatccttatg aacaaaatcc
    52801 taaagaaaaa ttgcaagaaa ccaaacagca attatccatt gttcacgagc agcaaaaaaa
    52861 gataacgaca gcgttaggtc agtgcagcgg ctatatccaa gaatttgaat gggtagaaga
    52921 agtcacactt gccgttgcag aacgggaaaa agtaaaagaa cggtttatcc atgccactta
    52981 tctgatcgtt ttgcaaggtt gggtagatgc agaagaaaaa cagaatttga tgcatgtgtt
    53041 aaacgaaact gtatcagaag aagatatata cgttagtttc gaaacaccaa actcagaaga
    53101 gattcagcag gaagtcccta ctaaattgaa aaaccatccg cttatcgaac cttttgaatt
    53161 gctgactgaa atgtacagtc tgccaaaata tgaagaagta gatccaacgc cttggatgac
    53221 accattttat cttgtcttct tcgggatgat ggtcgcagat gttggttacg gattgctgat
    53281 gctcattggg acaatactag ctcaaaaact atttgtttta ccccgcggga tgaaacgttt
    53341 cgtaaaattc tttgagattc tctcggtacc atcgatcatc tggggattga tctacagttc
    53401 atttttcgga caggcattac caaaagaact atttggtatc cgcttgcctt tcccaatcct
    53461 atctacgacg gatgacgtca atacgatttt gattttatcc gtgattttcg gtctgataca
    53521 gatcttggtt ggattattcg tggcagcaaa ggaaaatatc aggaggaaag attacttgag
    53581 tgctgtcagt gatggttttg cctggcaagg gatcctgatt gggatcgtta ttgcattgat
    53641 tggtgtcatg ttgataaaaa atacagcatt tgtttatctt ggcgcggggc tatcgatcat
    53701 tgctgcttta tgtatcttaa tcgtgccgat tatccaatcg ccgtctaaag tcaagggtgc
    53761 tgccaaagga gcgtataatc tttacggatt gactggttat atcggtgatt tagtcagtta
    53821 tacacgtttg atggcactag gtatttcagg cggaagtatt ggcgcggcat tcaatatgct
    53881 agttgctttc atgccgccag ccgctcgatt cagtgtaggg atccttttga tcatcgcttt
    53941 acacgcactg aatatgtttt tgacactgtt aagtgcctat gtccatggtg cacgattgca
    54001 gtatgtcgaa ttttttggaa aattttatac aggaggcgga cgtgcctttg acccgctgaa
    54061 aacggcggaa aaatacgtca acatcaatca taagaaaaaa aacaataaat aattggagga
    54121 tttttataca atgatggatt acttaattag tcaaaatggt ggaatggtat ttgcagtatt
    54181 agcgatggca acagcgacga ttttttcagg gattggttca gctaaaggtg ttggaatgac
    54241 aggtgaggca gcagcagcgt taacaacaag tcaacccgaa aaattcggac aggctttgat
    54301 tctgcaattg cttccaggta cgcaagggtt gtatggattc gttatcgcct ttttgatttt
    54361 tatcaactta ggaaatgata tgtcagttgt acaaggattg aactttctag gcgcttctct
    54421 gccgattgct tttacaggtt tgttttcagg tatcgcccaa gggaaagttg cagcagcagg
    54481 tatccaaatt ttagcgaaaa aacctgaaca tgctacaaaa ggaatcattt ttgctgcgat
    54541 ggttgaaaca tatgcgattt taggtttcgt tatttccttc ctattagtat tgaatgccta
    54601 agcataaagg aggaaaagca gatgaacgcc attgaaaaaa tcatctctca gatgaatgaa
    54661 gcagcagagc aagaaagagc ggcgttagag caagaagagc gaatgaagat cgatcaaaac
    54721 tttgaacaaa aacgtacgca aatcgaaaca gaacatcaaa aacaaaaaga aaaacaaatc
    54781 gaattacttg aaaaaaaata ccgtcagctt aggaatcgcc aacaagtaga agtacgacaa
    54841 gaaaatttga atgcgaagca ggaattttta cgacgattgt ttgcagatgc aatagctgaa
    54901 atggagaatt gggatgaatc tgaacaaatc cagtttatca aaaattcatt gtattcatta
    54961 cctttgacag gcaaagtaac attcattgct ggagaaaaat cagcagctta tctttctcag
    55021 acattgctgg atgaatggaa caatgaactt ccctttatga tggttttaag tgatgaaact
    55081 gttgctgatc aagcgggttt tctgataaac gatcaaggag ttcagtataa ttttcttttc
    55141 agcagccttg tacaagatat ccaaggaacg atgagttttg agattgccaa tcaattattc
    55201 gaataaggag ggatcagtgt atggaatacc acgaactaaa tcccttgatt cgcggaagag
    55261 agcttgaact tttgtccaat gagacatttg aacggatgat tcaaacaaat tctgtcgaag
    55321 cacttggtga aatattgaaa tccacgattt acagtccata tatttatgac ggatatgaat
    55381 atgacttcga acagaatctt ttaaaggagc agagccgtct atttcgctgg ttaaaggaat
    55441 cagcaccgga gcctgaaatc gtttggatct atacgatgcg ctatactttc cataatctga
    55501 aggttttgac aaaagccgag atgacaaatc aaaatctgga ccatttgtat atcgacgatg
    55561 gattttattc attagaaacc ttgaaggatg ccattcatac gcaagtttca aatgaactcc
    55621 ctgaaagcat tatggacagt atacgagaag tacgtgatta ttttgaagag tctaccattc
    55681 ttcagggaat tgacgtgatt tatgatcgac agtttttgac agagcagcga cggcttgccg
    55741 ataagctagg atatcaagaa ttgctgacag aagtcattgc ttttattgac ttgaccaata
    55801 tcacaacgat ggctcgagga atattgcaga aaagaacata tgggttcatg acgacggtac
    55861 tttccagctc gggaagtatc gaaaaagaag tatttttgaa ctttgtagat aaagatatgg
    55921 aagattacac gaattttcta ttagagacag attatgctga ttttctgcgc cctgtcatcc
    55981 gtgagggaaa tcttgatctc gtaaagcttg aacagttgaa agatgattat ctaagttcat
    56041 tgtatcaaga agcacaaacc caggctttcg gaccactgcc actactagcc tttttgaacg
    56101 caaaagaggt agaaagcaaa aaccttcgtt tactggttat cggcaaaaga agccatttcg
    56161 aaccagaaac aatcagaaag cgggtgagac aagtctatga cgcataagat cggtgtagtt
    56221 ggcgacaaag attctgtttt gccattcaaa ttgtttggct ttgatgttcg ttatggtaca
    56281 accaagcaaa ccgttcgtca ggcaattgaa gaaatggcaa agaatgagta tggcgtgatt
    56341 tatgtcacag agcaatgtgc agcattgagc ccagaaacga tcgaacgtta caaggaacaa
    56401 atgatacctg ctatcgtatt gattcccaat catcaaggat cattagggat agggctggaa
    56461 gaaattcaaa aaaacgtaga aaaagcagta ggtcaaaata tcttatagta tgaaaaggag
    56521 atagaaattt tgcaaattgg aaaaatcata aaagtctccg gacctcttgt aatggctgag
    56581 aacatgtctg atgccagtat ccaagacatg tgtctagtgg gagatctagg agttatcgga
    56641 gaaattatcg agatgcgtgg cgatgtggcg tctattcaag tatatgaaga gacttctgga
    56701 attggtccag gcgaaccggt tcgctctact ggtgaagctt tatctgttga attaggacca
    56761 gggatcattt cacaaatgtt tgacggaatc caacggccat tagatacctt tatggaaatc
    56821 acacaaagta atttcttagg gcgcggagtt caattgcccg cattggacca tgagaaaaaa
    56881 tggtggttcg aaccaacagt agaagccgga gaaacggtga gtgctggaga tgttatcggg
    56941 atcgtagaag aaacaaaagt tataaaacat aaaatcatgg tgccaaatgg gataaaagga
    57001 acgatcaaaa caatcgaaaa aggttcattc actattgatg aaacagtatg tgtcattgaa
    57061 accgaaaatg gtgacaaaaa tttgacgatg cttcaaaaat ggccagtaag acgtagtcgg
    57121 ccaatcaaag aaaaattaaa cccggatgca cccatgatca ctggacagcg agtgattgat
    57181 acattcttcc cagtgacaaa aggaggagca gcagctgtac ctggtccttt tggtgcaggg
    57241 aaaacagtcg ttcagcatca aattgcaaaa tgggccgatg tggacatggt tgtctatgtg
    57301 ggatgtggcg agcgtggaaa tgagatgacg gatgttttaa atgaattccc tgaattgatt
    57361 gaccctaata caggagaatc gttgatggaa cgtacggtat tgattgctaa tacatcaaac
    57421 atgccagtag cagctcgaga agcttctatc tatacgggaa tcacaattgc ggaatatttc
    57481 cgtgacatgg gttatgacgt tgctatcatg gcagactcca cttcacgatg ggcagaagca
    57541 cttcgtgaga tgagcggacg tttggaagaa atgcctggtg atgaaggtta tccagcttat
    57601 cttggttcac ggcttgcgga atactatgaa cgatctggaa gagtcattgc attaggatca
    57661 gaaggtcgcg aaggaagtat aaccgcaatc agtgctgtat ccccgtctgg aggggatatt
    57721 tcggaaccag tcacacaaaa tacattgcgg gtcgtaaaag tattctgggg tcttgattcc
    57781 agtttagccc aaaaaagaca ttttccttcg atcgattgga tacaaagcta ttctctttat
    57841 tcaacagaag tagggaagta tatggatcat atccttcaag ctgactgggc atccatggtc
    57901 accgagggca tgcgtatttt gcaggaagaa cagcagctga atgaaatcgt gcgtttggta
    57961 gggattgatt ccctttcaga taatgaccgt ctgacattag aagtggcaaa atccattcgt
    58021 gaagattatt tgcagcaaaa tgcttttgat gatgtcgata cattcacttc aagagagaaa
    58081 caattcaaaa tgttgaagat gatcttgacc tttggtgaag aaggacgccg tgcgttgtcg
    58141 ttaggtgctt atttaagtga gatcatggac ggtaccgtat cgattcgtga aaggatcgga
    58201 cgaagcaaat atatcccgga aacagaatta gaaaaactag atcaaattat tggtgaaatc
    58261 aagcaaacga tgcaaacgat cgtttcagaa ggaggcatga gcaatgatta aagaatatcg
    58321 tacgatcggt gaagtcgtcg gtccattgat ggcggttgaa aaagttgctg gtgtcaaata
    58381 tgaagaatta atcgaagtcc gtatgcaaaa tggcgagatt cgtcgtggac aagtattgga
    58441 agtccaagaa gataaagcaa tggtccaaat attcgaagga acaagtggta tcaatttacg
    58501 tgactcttct gtacgatttt taggccatcc tttagaacta ggtgtatcgg aagacatgat
    58561 cggtcgagta ttcgatggtt tgggacgacc gaaagataac ggaccagaga tcctgcctga
    58621 aaagcatttg gatattaacg gagaagtaat caatccagta gctcgggatt atccagatga
    58681 gtttatccaa acaggtatct ctgcaatcga tcatttgaat acattagttc gtgggcaaaa
    58741 attaccagta ttttctggct ctggtcttcc tcataaagaa ttagctgctc agatcgcgcg
    58801 acaagcaacg gtactcgatt catcagatga tttcgccgta gtctttgctg ctattggaat
    58861 cacttttgaa gaagctgaat ttttcatgga agattttcgt caaacgggcg caatcgaccg
    58921 ttctgtcatg tttatgaatt tagcaaacga ccctgcaatc gaacgtatcg ctactcctcg
    58981 tatggctttg actgctgcag aatatcttgc ttatgaaaag ggaatgcatg ttttggttat
    59041 catgacagac atgaccaact atgcagaggc attgcgagag atttctgcag cacggcgaga
    59101 agttccagga agaagaggat atcctgggta tctttacacg aacttagcta ctttattcga
    59161 acgagcagga agaatccgcg gactaaaagg atcggttact caaattccga ttctaacaat
    59221 gccagaagac gataaaactc atccaatccc tgacttgact ggttatatta cagaaggaca
    59281 gatcatcttg actagagagc tttacaagag tgggattcag ccaccaattg atgtactccc
    59341 gtctctttcg cggttaaaag ataagggaac tggacccgga aagacaagag aagaccatgc
    59401 agctacgatg aatcagcttt ttgcagccta tgcacaagga aaacaggcaa aagaattagc
    59461 cgtagtttta ggtgaatctg ctttatctga tgtagacaag atctatgcga agtttgctga
    59521 gcggtttgaa aaagaatatg tcaatcaagg attctacacg aaccgttcga ttactgaaac
    59581 acttgatcta gggtgggaac tgctatcgat gttgccaaga accgaattaa aacgaatcaa
    59641 agacgacatg ctggacaaat atctgccaga agggaagtga gttctgatgg cacgattgaa
    59701 tgtgaatccg acccgcatgg aattgactcg attgaaaaaa cagttgacaa ctgccacaag
    59761 agggcataaa ttattaaaag ataagcaaga tgaactgatg cgtcaattca tcctgttgat
    59821 tcgaaagaac aaccagctgc gtcaagaaat ggaagagtct atgacagaag caatgtctga
    59881 ttttgtattg gcaaatgctt cgatcacgga acctttcatc gaagaattat ttgttttgcc
    59941 ggcggaaaac gttgatttgt ctatcgtaga caaaaatatc atgagtgtaa aagtacctgt
    60001 gatgaatttt gaatatgatg aacagctgac agacacacct ttggaatacg ggtatttgaa
    60061 ttccagtgcc gaactggatc ggtcaatcga tcggtttact accctgcttc caaaactttt
    60121 ggaactgaca gaaatcgaaa aaacttgtca actgatggcg agtgaaatcg aaaagacacg
    60181 tcggcgagtc aatgcattag aatatatgac gatccctcaa ttagaagaaa cgatctatta
    60241 tattcgtatg aagctggaag aaaacgagcg cgcagaagta acaaggttga tcaaagtaaa
    60301 aaatatgggt accactgact aagtggtatc tttttttaaa agaggaaaac gatgattaaa
    60361 caaagcaaac aaataaagaa acgtttgccg gctgttcagc ttctcgcatt aggatttttt
    60421 ctcctgattt tagttggcgg cggcctactt accctaccat tttttagtaa tagtgggcat
    60481 gggacaaatt ttatcgatgc gcttttcact gcaacttctg ctgtctgtgt aacgggattg
    60541 acaacattga atacagcaga gcattggaac agtgctggtc aatttttgat catgcttttg
    60601 attgagatcg gcggtcttgg ttttatgatg gttccgattc tatgctttgc attgataaag
    60661 aagaaagtca gtctcagcac acgtattata ttaaaagaag cgctgaatct agaagaagta
    60721 tcaggtgtga tgaagctcat gctttacatc ctaaaattgg cctttgttat ccaattgatt
    60781 ggtacggttg ctttatcttt tgtatttgtg cctgaatttg gctggttgaa aggtatctgg
    60841 tacagtttgt tccatgcaat ctctagtttt tgtaatgcag ggtttgattt gttaggagac
    60901 agtttagcca atcaccagca aaatgtttat ttgatcatgg tggtatctgc tttgatcatt
    60961 tctggtgggt taggcttcat cgtatggcgt gatttactgg aatatcatca gaaaaagaag
    61021 atgacgattc attcaaaaat cgcattaacc gttacaggta cccttttatt aggcggattc
    61081 gttgtgttct ttttcacaga gcgcaatggg gcaacgctag tggaagggaa tatgtttcaa
    61141 cgattggcaa acaccttttt tatgagtgtg acacctagaa cggctggata ttattcagtt
    61201 gattacctcc atatgagcca tgcaggtctg attttaacga tgtttttgat gtacatcggc
    61261 ggaacatctg ggtcgacggc cggcggattg aaaacaacta cgttaggtgt gttgctgatc
    61321 cagatgcgtt cgatgttgaa aggacgtacg agagcggaag catttggccg taccatccga
    61381 caaggcgcag tgttgcgggc acttacttta ttttttgtta cgttgacgtt gtgtgtagtc
    61441 gccatcatga ttttatcggt gactgaaacg atacctaaaa cttctggcat cgaatatatt
    61501 gcttttgagg tcttctctgc gtttggtaca gtaggtctta cgatgggatt gacgccagac
    61561 ttgactgcaa tagggaaatt gatcattata gcgcttatgt acattggacg agttggtgta
    61621 ttgactgtgg tcttctctct gatgacaaaa gcacaaagaa cacaatcaaa atacaaatat
    61681 ccagaagaaa gtgtcatgat tggataattt catcttctga cagaaaccta gtgatttagt
    61741 aaaataagaa aataaaataa tttttcttgc ttcttggata ctttaagtgc aaaatgttcg
    61801 tttatttttt gaggcactac ccgttgttga acctcgggta gtgcctcttt tttattgaaa
    61861 ggaatcaata agatttgatt cctttattta tcaataggtt ataattcata tttttttatt
    61921 ttttctttta cgatacttag tccagaagct aaaatttcaa ggttattaga ggatagggaa
    61981 attcgaacga atgcatctgg ttgcgcacgt gtagtaaagc gtctggaatg ataaagtcgg
    62041 ataccgttag caagaaagtc attctcaatt atcttagggt caatctcagg atcaactgga
    62101 agaattcgat agtaagggac acgattcgtt ggtttttcta ctttgaaaag agaatcaaaa
    62161 agctgattgg ctctttttgt aagacttaat ttagtttcta agatcctatt tgcttcattt
    62221 gaatggagga tttgagtgat gacttccaca tctaatccag aagttttcac atttatatta
    62281 aaaattgctt gttctatctt gctttggaca tgtactggaa ctacaagata agcaactcgc
    62341 aatccagaac aaataaattt tgtcattcca gctaagtaga ttgtttggtt aggtaataaa
    62401 ttttggaaag gaggaatgat cgtatgttga tagtaagttg ttaaaaatga atggatatca
    62461 tcttcaataa cccatagacc ttctttttca atcacttcgg ctaattgctc tcgtcttttg
    62521 tgagagattt gaaaccctat aggattatta caagaaggca taagaaagac accatgaatc
    62581 ttcttttttc tacattcctg aatcaatata tcaggtcgca ttccttgctc gtcaaaatca
    62641 attggaacga tctctaaatg atataactga gccaattcaa tgaaattagc gtatgtatat
    62701 cggtctgttg ctattctatc acctggagag aaaagtgcag aaagtgtgat agccaatcca
    62761 ttttgaacac cggaaacaat agatagagat tctaaggacg gaatgactcc ttgagttttt
    62821 aaccaatttg ctgcagtagt caattgaaaa tttgtgcctt tgggatcttg gtaattaagc
    62881 aaaccaacaa gatttgggtt attactagtt gattgaataa acgggacaac gaatttatta
    62941 cattcttcaa aagaactaac cagaccaaaa tcaatgatat gttcggttac ttcattggta
    63001 gagatggtga tggactcaaa gacattggga gaaataaatg tgccacttcc aatattcgta
    63061 tacagcaaac ctttctcaat tccatattta taagccttgc caacggtagt aaaatttaaa
    63121 tctaaataat cagctagctc tctttgggag ggtaactgag tgtttttctg taatttattc
    63181 tttaaaatat cttgttctaa ttgttgaatc aacgatcgat aataaggacg cttcaatttt
    63241 tgtttgtctg gtcgccaagt taacgggtaa ttgtcataag aattaatagg cattttctcc
    63301 actccttaaa attgtatacc atacaatttt accattgatt gtattgattt tagaagttaa
    63361 tcttttgtga ggagggaatt gtctatgaaa attattaatt ttgaggaagt agtagcttct
    63421 tttagttttg aagaagcgat tcaagtaatg aaaaaatgtt tttttgatta tgaaagtggt
    63481 aaaatcagcc aaaatcctcg attggtggaa attttacctg acggaaaagg caaaaatatg
    63541 tttgcgatga tgcctgctta tttgggggag aacagatatt ttggcacaaa agtcattacc
    63601 gcttttccgg ataatcatca gtatcattta ccttctcatt taggagagat tttcttgttt
    63661 gatgctcaaa acggactacc caaagcattg ataaacgcaa atgcagtcac ctggattcga
    63721 acagctgctg tatctgcgct ggcaacagat tacttagcaa atccgcatgc agaaacactt
    63781 gctttaattg gagctggtca acaagcattg tcgcatttga ctgcgatttc taccattcgt
    63841 cccatcacta cagtgtttgt ttacgatatt ttagaagaaa gacgaaatac ttttatcgct
    63901 aaagctaaaa aacagtatcc taaaataacg tttataaatg caatatcagt agaagatgca
    63961 gtacgtccag cggaaatcat ttgtacgttg acctctagta aagaggcatt tcttcaaaaa
    64021 gagtgggtaa gggaagacgc acatatcaat gctgtgggca catttactcc tgatacaaga
    64081 gagataagta catcgttgat ggaaacttct caaatctatg tagatgatta ctcagctgcc
    64141 ttaacagaaa gcggggacct gcttatagcc atggcagaag gagatttaga ggaatcttgt
    64201 attgttggta cattaggcga attagtttct gagaaaaaaa cattttataa aggagaatcg
    64261 aggccgacga ttttcgacgc agttggtcta gctattgaag atctttgttg tgcagaatat
    64321 atttataaca aattagagaa aggggcttta aaatgaactt agattattac gtagttgatg
    64381 catttgcaga tgaggtgttc aaaggaaatc cagcagcggt ttatgtgcta gaagaatggc
    64441 tgccagaagg tacgatgcaa aaaattgcca ttgaaaacaa tttatctgaa acagcattta
    64501 cagtgaagaa aaaccaagaa tttgagctta gatggtttac gccagatcga gaaatcgatc
    64561 tttgtggtca cgcgacatta gcaacagcat ttgttttatt taactattac aaaatacctg
    64621 atgaaacgat taaattttct actcaaagcg gtaatctatt tgtgacaaga attaaagatt
    64681 attattacat ggattttcct agtattatgc cgaaaaaagt gccgatattg tctgaatatg
    64741 aagaagcgat tggggctaag attaaagaag cctacttagc acgtgattta tttttcgtat
    64801 tagaagatga aaaaacggtg gctaaattgc agccagattt tacagctatc aaaaattttg
    64861 aattaggaat aggagtcatc gtgacagcag aaagtgtgca aaaagacttt gtttctagaa
    64921 ccttctttcc aaaattaaca atcaatgaag atccagtatg tggatcagca cattctaatc
    64981 ttattcctta ttgggcagaa agaatgaata aaacaaaatt gtcagcttat caaatgtcat
    65041 caaggggcgg ggatctagaa tgtgaattaa aagaagatcg tgtgataata ggaggaaaag
    65101 cagttttgtt ttctaaaggt acctcgttta tttgatttct ttcaaatgaa ttaaaaataa
    65161 attggtggag agtggcaacc ttatagctac aatggttgtt aaaaaaagac gcaaactttt
    65221 tcaatttaat gaaaagtttg cgtctcattt taattattgg tgtttgtttt ttattcaatc
    65281 aagagtaaaa tgccccatac taactatcct cggatgactt cgattttata accatcaggg
    65341 tcaatgacaa agtagtaaga aggcgcagtg ccaggtaatc cttttaagtc agtaatctca
    65401 agaccggcag ctttatgttg ctcgtgtaat ttttctagat catcagctgc tatagcgata
    65461 tgaccatagc cgtctcctag atcatacgca ccatgatcat agttgtaagt caactctaat
    65521 tcatagtcat ccccaggaag tgtcaaataa acaagtgtaa atttgttttc tggaaaatca
    65581 cggcggcggc tttcttcaaa accaaatgcc ttttgataaa attcgattga tgcttcaaga
    65641 tctttcactc gaacacatgt gtgagccatt ttcatagatt catctctcct tttcctttta
    65701 ctcaatcata acaaaaagaa gtaaggaaat agttgatttg tgcttgttca tgagaaattt
    65761 ctcatgtaaa atggatagaa aataaaactg ttaaggtgga aactattcat ggataaacca
    65821 atttttggtg aaaaaaagca atttgctgat tatcaaaccc gttatgcagc atatattgtc
    65881 atagaaagag atcagcagat tgcagtaatc gaggctccaa atggtgcttt ttttcttcct
    65941 ggcggggaaa ttgaaggaga agagacgaaa gaagaagcga ttgtccgtga gctgatagaa
    66001 gaaatgggaa ttgtggcaga aatttcttct tatctgggag aagctgatga gtatttttac
    66061 tcgaattatc gtgcaactta ttattataat ccaggatatt tctttgttgc tgattcttgg
    66121 aagcgtatag gagaaccaac tgaaaagacc aataaaattt ggtgggtgag ccctcaagaa
    66181 gcgcttgtga aattgaaacg tggtagccac cgatgggcag tcgagagatg gatcgaaaaa
    66241 aataaaaact gaaagaaagc gagtagatca gctttctctc agttttttta tttattacag
    66301 tacatatttt ttgattgctt cagctacacc gtgctcgtcg tttgatgaag tgatgacatt
    66361 tgctgcttct ttgacaagag aaacggcatt tcccattgct actcctagac cagcatattc
    66421 aatcatggat aagtcgttct cgttatctcc gatagccatg atttcatctt gatcaatacc
    66481 aaggtgctgt gcgagattcg caactgccgc acctttactt gcttctttat ttagtacttc
    66541 gaagtaatag ggcgcacttt tgaccgttgt gtatttatca cggaaagttt gcggtaaacg
    66601 cgcaattgct gcatctaaaa tttctggttc gtcgatcatc atcattttga cgatgttcat
    66661 gtctggtgtc atttcttcag gtgttcgata ttttagcggc atcttgacta aacttgcttc
    66721 gtggatcgta taagcgctga tatctcgatt aggcgtgtag atcgctttgt catcgatcga
    66781 atggagatga ctgccgacac ggcgtgccat cacttcgatc tctaggaaat cttcatgtgt
    66841 cagtccgtga cgggcgatga ttttacctga tttcgtttgt tgtacgagtg ccccgttata
    66901 agtaataacg taatcattat cttgaaaaag gttcaactcg tttaactgtt cctggacacc
    66961 tggtaaggga cggccagtgc ataaaacgat cgaaacacct tttgcaacag cagcggcaat
    67021 cgcttctttt acttcttttg ttacttctct tttctcattt aataaagtac catcgatgtc
    67081 gatagcgact agtttgatag acataatttc ctccaatata ttttaattta tttcaatcaa
    67141 tgcgccatta cggatatggc tggcaaattc ttgataagtt tcgtcaaata aatcataatg
    67201 atcacgcaag gacggatcaa ccatttcttt tggaaagaaa aatcgctcat ctccttgttc
    67261 ttgtcccgct aatgcagcaa caagctgact aacctgtgat aattctatca aagttccgtc
    67321 atttcgcaaa atctcgattt gtgtgcgatg tctgccttgt tctgggcgat aaaaatcata
    67381 aggtagatcg tagctagaat tcacagcagt gtaataaaca ggattatatc cgaccttttc
    67441 tactaacaaa gtgagttctt ggactaattt tgaatcccgg ttgccagaaa aagtagcaga
    67501 tttcagtggt ttacgattca aaaaacgttt agctaaatca tttaaaatag gatcagcaga
    67561 ttcagaccat tgagtaaagt aagtgcccaa gaccccatca tcaagtttga ggtattcttc
    67621 taaagtaaag cttccgtcaa gaaatggcag aagtaattga gaatggagtt caaaactgct
    67681 ggcatcttct tgatacaact cgtgtgcgcg atgaagcaga tgctccaaaa ttacttccat
    67741 accacgggaa acaggatgga agtacacttg cacatacatt tgatatcggc taacgatata
    67801 atcttccact gcatgcatgc cactcatgga aaaagcgatc ccgccttcat aaggacgaat
    67861 cacacgtaat attcgggtaa gatcaaatgt tccatattct gttccagtga aataagcatc
    67921 ccgaagcaaa tagtccattc gatctgcatc gatctgacta gaaatcattt ggacaacttg
    67981 tgggttgggg taagtttttt ggatcacact agctaccttt tcaggaaaac cttcttctac
    68041 tcggttaaga atctgataca cttctgtttc tggagaagtg atgatctcta cagtgatggc
    68101 ttcatgattc gtatggaaga tatgttcaaa tgtatgagag taaggaccat gaccgacatc
    68161 atgcaacagt gccgcacata aagtcaccag ccgttcctga tcatcccagc ctccgttgcc
    68221 tattttttct tttgaaaaat ttcgagaaaa gatatcgcag attcgtcttg aaatctcata
    68281 aacgcctaat gaatgagtaa aacggctatg ttctgctccg tgaaaagtga aagaagaagt
    68341 gcctaattgt ttaatgcgtc gtagacgttg gacttctttc gaattgatca aatctaagat
    68401 tacttgatgc tggacatgga tatagttatg gactggatca cgaaaaactt tttccatagg
    68461 cagcatttga tatttataag gggttgtcat aatgtagctc ctttatgtta ttacgttgtt
    68521 ccattctctg gatttggttg ttccattgct ccagctggat ttcttttttt agccagtcgg
    68581 tagaatcctg taaatcactt gcagaataca gcttttcaaa agcttttgca aatgcttctt
    68641 tgacttcttt tacaaaaagg ggttggtcaa gcagttcttc aagtgttgcc attgtagcag
    68701 gatccactgc aggatagcca tttgtaccaa agtcttcttt taaagcagat tgataaaatc
    68761 gcttcatgac ttgcccgcgt ttttcctgat taccgttgac acttaagtac atcataacag
    68821 aaatcccatt tttgatccga cgctgagcga taccggcaaa ttttttgcca tggatgctta
    68881 aatcataagt tccaggacaa taagaatggg tgatttcgaa tgcttgtatc ggtgcctttg
    68941 gaaaagcgta tttagtcaat aggagcattt gctcgtaagc gtcatctatg gttatttttt
    69001 ttgtgtcact ttgggggaaa atcaaagaaa tattcaaaat tccttcatct gatacgatcc
    69061 ctaatccacc tgaatttctg atcactggag cgtaacctgc atctttcagt gtttggatcc
    69121 cgtcacttag aaaaggagtt cgaacatcct tcatacctaa gatgactgtg cagtcatatt
    69181 gccagaaatg taaaaagatt tgctggtgtt ctttagaata ttccgttaat atatctgtta
    69241 atgcaaaagg ggaaaagtcg tttttttgat aaatgtgctg atctagtcga atcgcagggt
    69301 tcattcaacc ggctcctttg tataaattca tattttctac aatattatac tctaaaatca
    69361 aagagttgtt ttggaaaaaa ggttttctgt aaaaatggac aagttggttg acaaaacaaa
    69421 agaaactagg aacaatgtag ctatgagaag taaaggagaa tgaataatgg aattatcaca
    69481 aggaacaccg atttcaatca aattgcgtac aaaagtaaaa cagcaagggg aagtgcaaga
    69541 tttttatttt gatttgaaag ggcaaatggt gacaattggc gatacgctgt acatacgtta
    69601 taaagagatt caggaggaga cgggcgatga gattcctgta acgatcaaat tagttccaga
    69661 tggtcatgta cagctgatcc gtgcaggaga aatgcggatg cgtttgaaat ttggctataa
    69721 agaacggtta gaaacatcct atcgaacacc atacggtatg atccagattg ctacttttac
    69781 gaaagaactg catgttagtt tgaaagaccg tcccacagga gggaaggttc gaatcgatta
    69841 tgatctgttc atgggaccgg aaaaaatcgg cgaatattat ttgaccttgg attttacagc
    69901 gtaaatataa aagaaaagtt tgattttttg tgtctgattt tgtatgataa ggagtagact
    69961 gtgaaaggac gtgtcctgat tggaaattag tgtatttgaa ggtgcaaaca aaagcgaatt
    70021 atcaatgatc gaagtagcac acgcgatctt agaacaacgt ggcgatgtca tggatttttc
    70081 tgatttagct aaccagatcc aaaactatct tgggaaatca gacagtgaaa ttcgtgattc
    70141 actcgcacaa ttttatactg acttgaatat tgacggcagc tttatctcat taggggataa
    70201 tcgttggggc ttgcgttcat ggtatgctat cgattcgatc gatgaagaag taaaccatgg
    70261 aatggacgaa gaggatgaag atactccacg tcgccgtaaa cgcaagaaag tcaacgcctt
    70321 tatcaatgat gatgaagacg cgatcgatta caatgacgat gacccagaag atacagatct
    70381 gacagaagaa gatgacgatg atctgtttga tgacgatgat gatgaagatg aagaaatcgc
    70441 tgcttataat tctgacttgc aagaaatcgg agcagatgac ccgacagatg atgaagaaga
    70501 cttgccagga aatatcgaag aagatttaag tatcatagac gaagacgatg atgatgaaga
    70561 ttatgaagag gaagaatttt ctgactctga aaaagaataa acattatttt cttacgagag
    70621 gttgtgacag agacgatcag cctatcagaa taaggaggtg tgacacgatt tttgtcacac
    70681 cttctttttt gtatataaaa atcccaagta aatacataaa aaataaaaaa attgaaactt
    70741 ttagcgcacc ttgtacgtca tattaagtga ggcagaaagg agtggagaat gatttttact
    70801 ggatataaga aaaaacggca gatcgaaaaa taccgtcacc tgctgaatgg actcatcgaa
    70861 actgattatc aaaaaatgtt ccgtatcacg atgaattacg tacatgataa agaagaggcc
    70921 ttagatgtga tgcaagatag ttttcataaa gccctgaact attttgaaaa agaaaaagag
    70981 atcgagcatt ttagtgcatg gttttatcgg atattgatcc gcacggcatt agatagttgg
    71041 cgcagacaaa aaaggacgcc tgtggactta tttgaaattc aagatatccc ccaacagtta
    71101 cctttagaaa cttccgttgc agagctccat atgattttag ataaaataga cagtccggaa
    71161 aaagagattc tgatcctcta cttttttgaa ggatttcgtt tgaaagaaat tgcgactatc
    71221 ttggatatga atgaaaacac agttaaaacg aaaatgtacc gctcattgaa tgctttacgt
    71281 caaatcctag aatgaaggag agaagagtgc catgtattcc caaaaagaaa atttaaaaaa
    71341 actaaagaaa acttataaag aacaagcaat tcccaaaggg cttaaagagg agatccgcca
    71401 gcgttttatt atcgaagagc aatcatttat aaaagcaaag cggagaaaga gacgtctcca
    71461 agggttcgga gtatctttgg ctatcgtaat gattacaaca agtagccttc tttttaatag
    71521 tcaagttcga agctttgcag aagatttacc catcttagga tcagtcattg aattgatctt
    71581 aggcgaacgc tttactgatc gatctgaaaa aatcgatatt caggtaccga agatcaatac
    71641 acaaaatgag aaagaaaata aaacaattca tggattaaat caaaaatact ttcgcgaagg
    71701 acaagcagat tttgaaaaag ctgaaaaaga atatggaaat tttgaaacgg atcattacca
    71761 agttttggga gattatcaga aaatcgtaga cgataaccgg tttctcgtga ttgaaaggca
    71821 gatcacccaa acagcagcag atagccatgt tgaaaaaaga tacgacacaa tcgacaagaa
    71881 aaacagtgtc cagctctcac ttccactttt attcaaagat gacacctatc tatctgtttt
    71941 gacaaaagaa gtcaaacggc agatggccga acaagtcaag gaagatccat ctaagtacta
    72001 ttggactgag caagatattc aagaagggac gatagaaaaa ccaacacttg ttacgcctac
    72061 acgaagtttt tatttgaaca aagagcatca attagttttg actttttctc aatacgaaat
    72121 tgctcctggt tatatgggta caccagaatt tgtcattcct aagtccgtga caaaaacgat
    72181 tttggcatcg gaagattatt tggatcatta gacgagaagt agttgcgact agcagtttca
    72241 attttcaagt aagtacaagt aaataataag aagagaaaaa gagaaagaag agatatagtg
    72301 aaaagaaatt atttagttat cagtattatt gctttatccg tgcttttgtt tttcgaaatt
    72361 acttcggtgg cctccttgat caccgaagta aaaggacaaa cacactcttc ggagcattcg
    72421 tcacaatctt tcaaacaatc agaacaatca accattaaaa gccaatcaac tgaaacagct
    72481 aacgtcaaag aagccattca agaatcagcg gaaaaggtac aaagtcagtc atcacaatca
    72541 acacaagaca gtacaaaaac gagccgagat ccggctgtca aaagcgtcgc aatcagcttt
    72601 gatgatggac caggagcgac cacaacaccg cagcttctgc gaatcttaaa agaaaaaaac
    72661 gtgcatgcca cttttttcgt cttaggagaa aatacggcgc agcatcctga aatcgtgaag
    72721 cagacagctg aagcagggca cgagattggc aattacacat acgatcatca gaatctggcc
    72781 actctttctg cccagtcgat gacggaggaa gtgacgaaag cagacactga gatcaaaaaa
    72841 gtcactggca aaacccccac ttttgttcgt ccgccctatg gttctgtcac gaatgtagga
    72901 gcaacgatca tccagcgacc gatcatcgaa tggtctgttg attcagaaga ttggaagaca
    72961 agaaatcctg atttgatttt gcagaagatc caagcaacag tatacgatgg ggcaattatt
    73021 ttattccatg atatctatcc tgaaacgatt cgtgccgttc ctcaagtgat cgattatctg
    73081 aaagagcaag ggtatcgcat cacgacagtt ggggatttat tagggcatcc aacggctgtc
    73141 gagaactatt atggcagaaa cgatcatcgg ccagttcagt aagtgagaca agtatcttta
    73201 ataaataaca cattttaata agtagttgaa cacataacta ccttacttgc aaaggcttaa
    73261 caatatctat acaggtacaa caaaaaactg tccaccaatt ttctttggcg gacagttttc
    73321 acttaaaaat aaagaagcaa ctattcgtaa attatgctaa aatagcagta gaacgcgtcc
    73381 tgagggaatc gaacccccgt ctcaagaacc ggaatcttac gtgatatcca ctacactaag
    73441 gacgcaagca ctgggataat tgtaactaaa cagataaaaa attacaaggg gattggacaa
    73501 aaaaatgaaa tttgagcaaa atttttcaca aaaacagcag cagacacaga aactagccat
    73561 gacgcaacag ttgcaacagt ccatccaagt tttacaatat aacagtgagg agctgttggc
    73621 attcgttgag aatcaagcaa tggaaaatcc attggtggaa gttgttgagc cggaatggca
    73681 gccagattac ataaaagctt cttcatcttc ttatgaagga gaagagacaa attacctaaa
    73741 tcagattcct gatacaaaag ggtctttatt tgattcattg atcgaacaag tccatttgaa
    73801 ttaccgagat acttttttga ggaaaatcgt tctttatctt gtagaataca tcgatttgaa
    73861 cggatttttg acgattagtt tagaagaagc cggaaaagag attggagcta cgcctatcca
    73921 aatgctcgat gcgttgactc tgattcagca attagaacca gctggagtag gtgcacgtag
    73981 tttgcaagaa tgtctcatgc ttcaaacaga acgagatgat tatgcgccgg aattagctta
    74041 tatcgtgttg gaagaatgtt ttgaggaact ggtggagcga aaatggaaag aaatcgcaca
    74101 acgtttttct gttgatctac atgctgttca gcagatattc gactatttac aaacgttgag
    74161 tccaagccct ggccggattt tcgaccgtag cagcgaattg tacattattc ctgatgtccg
    74221 ggtattagtg gacgacgata aaaatgtaca agttatctca aaccgaaaaa atcagccaaa
    74281 tatacgcttt caagagagtt acttcaaaca aatgtcacaa caagcagata aagaaactga
    74341 aaattattta aaagaacgga aacaggaatt cgaatggttg aagaaaacga tcctacaacg
    74401 tggggataca attttgcggg ttgctcaagt cattgtttcc cggcaaaaag ctttctttat
    74461 cgacaaggaa cgtccaatca agcctcttac gttaaaggaa gttgcaactg agatagatgt
    74521 gcatgaatcc acggtcagtc gtgcagtcaa cgggaaatat ttggaaacag atttcggtgt
    74581 atttgaatta aaaaaatttt tcactacacg aattcctacg aatagtacag aacagacaga
    74641 agacctttca gcagatacag cgaagaaaaa gctgcaggaa ttagtcgatc aagaagacaa
    74701 aaacaagccg ttgtcggacc agaaattggt tgaattgctg aaaaaagatg agatagcgat
    74761 ctcaagacga acagtagcaa aatatcgtga tttattagga atcccgagtt catcaaaaag
    74821 aaaacgttat gataactaat cagtcaaaag actagaaaaa gtatttcact ttttctagtc
    74881 tttttagttg aaaaacgaga gcgaaactgt tagacttaca gtcgtgaggt tgagatttcc
    74941 ctttattgat gtgaaattcg aatagttaat ttcttttttt atcgtatatg ggtcgtttta
    75001 agtctacatt ggacgtaaag tgtccaacta aggagatcgc tatgctggat gaaataaaaa
    75061 tgattgaatc tgttgcacca gatattatcg aagtgttgca agaacgctat aaaattttac
    75121 gaaatatcta ttggatgcag ccgattgggc gtcgaagttt atcggaaagt atggggatca
    75181 cagaacgagt cttacgaaca gaaacagacc ttttgaaaaa tctgaatttg atcgacacct
    75241 caaaaagcgg tatgacgctg acaactaagg gcgaagaagt ttatcaaagc cttgaaaact
    75301 tcatggatca gcttttaggt acgcatcaaa ccgaacaaca gttggcagaa tattttggta
    75361 accaacgctg tatcgttgtt tcaggaaaca gcgaagagca gaccaaagtg gctgatgcat
    75421 tcggcgaagc gctgagcgaa gccttagacc gactacttcc agaaggcgag aatatcatcg
    75481 ctgtgatggg aggaactact atggctgtgg tagccgaaca attgtctaat ctggaaaata
    75541 agaaacggca taacctgttt gtccctgcaa gaggcgggat tggtgaagcg ataactgtac
    75601 aggcaaattc tgtcagtgca agaatggctg ctaaagcaaa cggtaaccac cgcgcacttt
    75661 atgttccgga acaattaagt ctggcaactt acaattcttt actcaatgag ccatctatcc
    75721 aagaagtctt aaacttgatt agtgaagcga attgtgttat tcatagtatt gggcgtgcat
    75781 tacacatggc agcacgtcgt aagatgactg aaaaagaatt agtcatgctg aaacaagcaa
    75841 atgctgttgc ggaatctttt ggctactttt tcaatgaaaa aggtgaagtc gtttataagg
    75901 tccctagaat cggcatagaa ttgcaagatt tggaaaaagt cccgatcatc atggcaatcg
    75961 cgggcggaaa atcaaaagct aaagcaattc gagcttatat gaaaaatgca ccaaaacaaa
    76021 cgtggctcat cactgatgaa gctgctgcaa atgagatttt aaaaggggta accctttaaa
    76081 ataaatattt ttttgatttt cataaggagg aaatcttaaa tgacagttaa agtaggtatt
    76141 aatggttttg gacgtattgg acgtctagca ttccgtcgta tccaagatgt agatggaatc
    76201 gaagtagtag caatcaacga cttgacagat gctaaaatgt tggcacactt gttaaaatac
    76261 gacacaactc aaggacgttt caacggaaca gttgaagttc atgaaggttc attcaacgta
    76321 aacggaaaag aagttaaagt attagctaac cgcaacccag aagaattacc atggggcgaa
    76381 ctaggcgtag atatcgttct agaatgtact ggtttcttca cttctaaatc agcagctgaa
    76441 aaacatttaa cagctggtgc taaacgcgtt gttatctctg ctcctggcgg aaacgatgtt
    76501 ccaacaatcg tttataacac aaaccacgaa acattaactg gtaaagaaac agttatctca
    76561 ggtgcttcat gtactactaa ctgtttagct cctatggcta aaacattgaa cgacaaattt
    76621 ggtgttgttg aaggattaat gacaactatc cacgcttaca caggtgacca aatgactcta
    76681 gacggacctc atcctaaagg tgacttccgc cgtgcacgcg ctgctgctgc aaacatcgtt
    76741 cctaactcaa caggtgctgc taaagctatc ggtttagtaa ttcccgaatt gaacggtaaa
    76801 ttagacggag ctgctcaacg tgttcctgta ccaacaggtt cattaacaga attagtaaca
    76861 gttcttgaaa aagaagtaac tgttgacgaa atcaatgcag caatgaaaga agcttcaaac
    76921 gaatcttacg gatacaacac agacgaaatc gtttcttcag atatcgttgg tatgacttac
    76981 ggttcattat ttgatgctac acaaactaaa gtaatgacag ttggcgacaa acaattagtt
    77041 aaaactgttg cttggtacga caacgaaatg tcatacactg cacaattagt acgtacttta
    77101 gaatacttcg ctaacttata agatagacaa acgtacaagt gtaaattata gacatgtaca
    77161 tttaaaagcg gggaagcaat cgcgcttctt ccgctttttt tgataataag tttattcagg
    77221 aggaaataaa atggctaaga aaacagtgaa agatatcgat ttaaaagaca aaaaagttct
    77281 tgtccgtgtt gacttcaacg ttcctttgaa agacggcgtg atcactgacg acactcgtat
    77341 caaagcagca ttgccaacaa tcaactacgt tctagaacaa ggcggaaaag caatcctttt
    77401 ctctcacctt ggacgtgtaa aaacagaaga agataaagaa ggaaaatctt tagctccagt
    77461 tgcaaaacgt ctaggcgaat tattaggtaa agaagtaaca ttcgtacctg aaactcgcgg
    77521 agaacaatta gaagaagcaa tccgcaacat gaatgacggc gacgttgtcg tattcgaaaa
    77581 tacacgattt gaagatattg acggtaaaaa agaaagcaaa aatgatacag aactaggtaa
    77641 atactgggct tcattaggcg atgtatttgt taacgatgct ttcggtacag ctcaccgtgc
    77701 acatgcttct aacgtaggta tcgcttcaac tggtatccca acagttgctg gattcttgat
    77761 ggaaaaagaa atcaagttca tcggtgaagc agtagaagaa ccaaaacgac caatgattgc
    77821 aatccttggt ggcgcaaaag tttctgataa aatcggcgta atcgaaaact tgattcctaa
    77881 agcagataaa atcttgatcg gtggcggaat gacttacaca ttctacgaag caaaaggaat
    77941 caagatcggt aactctctag tagaagctga taaagtggaa ctagcaaaag aattaatcga
    78001 aaaagcaggc gacaaacttg tcttgccaat cgacaatgtc tgtgcaccag aattttcaaa
    78061 tgatgttgaa acacaagtaa tcgaaggaga cattcctgat ggtttgatgg ctttagacat
    78121 cggcccagca tcagtaaaat tatttgctga tacattacaa ggtgcaaaaa cagttgtttg
    78181 gaacggacct atgggtgtat ttgaaatgag taactttgct aaaggtacaa tcggtgtttg
    78241 tgaagcaatc gctaacttag aaggcgcaac aacaatcatc ggtggcggag actcagccgc
    78301 agcagcagaa caattaggat ttgctgacaa attcacacac atctcaacag gtggcggcgc
    78361 aagcttggaa ttgcttgaag gtaaagaatt accaggacta gcagcaatca acgataaata
    78421 aacgaccaag tttgctcaat tctgacgagt aatcgaacaa aaggtgaagg gagttttcat
    78481 gactccctag ccatttttca ataaattaag gagtgtgttc ctcaatgcgt aaacctatta
    78541 tcgcaggtaa ctggaaaatg aacaaaactg catcagaagc aaaagaattt gctgaagcag
    78601 taaaaaacaa aatcccttca aatgacaaag ttgattcagt catcggatct cctgcattat
    78661 tcttacaaga attaatgaca tcagctgaag gtacagaact aaaaatctca gcacaaaact
    78721 gctactggga aaactcaggt gcgttcactg gtgaaacttc accagcagct cttgctgatc
    78781 taggtgttca ttatgtgatc atcggacatt cagaacgtcg tgaatatttc catgaaacag
    78841 acgaagacat caataaaaaa gcgaaagcta tctttgcaaa tggtatgaca ccaatcctat
    78901 gctgcggcga atctttagaa acctatgaag caggcaaaac tgctgaatgg atcgaaggac
    78961 aaattacagc tggtttagct gatctttcag ctgaacaggt gtcaaacatg gttattgctt
    79021 atgaaccaat ctgggcaatc ggtactggta aatcagctga cgcacaaatc gctgacgaaa
    79081 tttgtggagt tgtacgtcaa acagttgaaa aactttatgg aaaagaagta tcagaagcag
    79141 ttcgtatcca atacggcggt tctgtaaaac cagaaaatat tgctgaatac atggcaaaag
    79201 aaaatgttga cggtgcttta gtcggtggcg caagcttgca agcagattca ttcttgtcat
    79261 tgttagacgc tgtaaaataa ttgttgaaaa tttgcgaaaa atgcaagaaa tgtttgcact
    79321 aatgagcaaa attaactaaa atcgtatatg agggaaatcc cttaggaaaa aacaaactca
    79381 aaggagagac aaaacatgtc aattattact gatgtttacg ctcgcgagat cttagactca
    79441 cgtggtaacc caacaatcga agtagaagta tacacagaaa gcggagcttt tggccgcgga
    79501 atggttcctt caggtgcttc aactggtgaa tacgaagcag ttgaattacg tgacggagac
    79561 aaagctcgtt atggcggtaa aggtgtaact aaagctgtcg acaacgtaaa caacatcatt
    79621 gctgaagcaa tcattggcta cgatgttcgt gaccaaatgg ctatcgacaa agctatgatc
    79681 gctttagacg gaactcctaa caaaggtaaa ttaggtgcga acgctatttt aggtgtttct
    79741 atcgctgttg cacgtgcagc tgctgactac ctagaagtac ctttatacca ctacctaggc
    79801 ggattcaaca caaaagtatt gccaacacca atgatgaaca tcatcaacgg cggatcacat
    79861 gctgataact caatcgactt ccaagaattc atgatcatgc ctgttggcgc tccaacattc
    79921 aaagaagctc tacgtatggg tgctgaagta ttccacgcat tagcttcaat cttgaaagct
    79981 cgcggattag caacttctgt tggtgacgaa ggtggatttg ctccaaacct tggttcaaac
    80041 gaagaaggtt ttgaagtaat catcgaagca atcgaaaaag ctggctatgt acctggtaaa
    80101 gacgttgttc ttgctatgga tgctgcttct tcagaattct acgacaaaga aaaaggtgtt
    80161 tacgtactag ctgactcagg cgaaggcgaa aaaacaactg acgaaatgat caaattctac
    80221 gaagaattag tttctaaata tccaatcatc tcaatcgaag atggattaga cgaaaacgac
    80281 tgggacggat tcaagaaatt aactgacgta ttaggcgaca aagttcaatt agttggtgac
    80341 gacttgttcg taacaaacac tcaaaaatta tctgaaggta tcgaaaaagg aattgctaac
    80401 tcaatcctta tcaaagtgaa ccaaatcggt acattaacag aaactttcga agctatcgaa
    80461 atggctaaag aagctggcta cacagcagtt gtatctcacc gttctggtga aacagaagat
    80521 tcaacaatct ctgatatcgc tgttgcaaca aacgctggcc aaatcaaaac tggttctcta
    80581 tcacgtactg accgtattgc taaatacaac caattactac gtatcgaaga ccaacttggt
    80641 gaagttgcag aatacaaagg tttgaaatct ttctacaact taaaaaacaa ataattcttt
    80701 tctaatgaag atacatgatc gactattgaa agatagtcga gtatgatcac ttagttaagt
    80761 aatcgaactc tctacttgct gaaatatcag caggtaga
//
LOCUS       DAYYEF010000006        71936 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000006 DAYYEF010000000
VERSION     DAYYEF010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 71936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.006"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1925)
                     /locus_tag="ACHA1B_000519"
     CDS             complement(<1..1925)
                     /locus_tag="ACHA1B_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HFM8701311.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEET"
     gene            complement(2008..3663)
                     /locus_tag="ACHA1B_000520"
     CDS             complement(2008..3663)
                     /locus_tag="ACHA1B_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFM8701312.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(3665..3979)
                     /locus_tag="ACHA1B_000521"
     CDS             complement(3665..3979)
                     /locus_tag="ACHA1B_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFM8701313.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4149..4409
                     /locus_tag="ACHA1B_000522"
     CDS             4149..4409
                     /locus_tag="ACHA1B_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HFM8701314.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            4423..4737
                     /locus_tag="ACHA1B_000523"
     CDS             4423..4737
                     /locus_tag="ACHA1B_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HFM8701315.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(5467..6021)
                     /locus_tag="ACHA1B_000524"
     CDS             complement(5467..6021)
                     /locus_tag="ACHA1B_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HFM8701316.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(6147..8076)
                     /locus_tag="ACHA1B_000525"
                     /pseudo
     CDS             complement(6147..8076)
                     /locus_tag="ACHA1B_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(8382..9098)
                     /locus_tag="ACHA1B_000526"
     CDS             complement(8382..9098)
                     /locus_tag="ACHA1B_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFM8701317.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(9099..10922)
                     /gene="glpO"
                     /locus_tag="ACHA1B_000527"
     CDS             complement(9099..10922)
                     /gene="glpO"
                     /locus_tag="ACHA1B_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004368 - glycerol-3-phosphate
                     dehydrogenase (quinone) activity [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HFM8701318.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(10936..12432)
                     /gene="glpK"
                     /locus_tag="ACHA1B_000528"
     CDS             complement(10936..12432)
                     /gene="glpK"
                     /locus_tag="ACHA1B_000528"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004370 - glycerol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006072 - glycerol-3-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HFM8701319.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(12568..14028)
                     /locus_tag="ACHA1B_000529"
     CDS             complement(12568..14028)
                     /locus_tag="ACHA1B_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8701320.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(14018..15313)
                     /locus_tag="ACHA1B_000530"
     CDS             complement(14018..15313)
                     /locus_tag="ACHA1B_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFM8701321.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(15645..16322)
                     /locus_tag="ACHA1B_000531"
     CDS             complement(15645..16322)
                     /locus_tag="ACHA1B_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HFM8701322.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(16352..17443)
                     /locus_tag="ACHA1B_000532"
     CDS             complement(16352..17443)
                     /locus_tag="ACHA1B_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HFM8701323.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(17544..17978)
                     /locus_tag="ACHA1B_000533"
     CDS             complement(17544..17978)
                     /locus_tag="ACHA1B_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFM8701324.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(18562..20019)
                     /locus_tag="ACHA1B_000534"
     CDS             complement(18562..20019)
                     /locus_tag="ACHA1B_000534"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFM8701325.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(20016..21911)
                     /locus_tag="ACHA1B_000535"
     CDS             complement(20016..21911)
                     /locus_tag="ACHA1B_000535"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFM8701326.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(21969..23744)
                     /locus_tag="ACHA1B_000536"
     CDS             complement(21969..23744)
                     /locus_tag="ACHA1B_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFM8701327.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(23794..25290)
                     /locus_tag="ACHA1B_000537"
     CDS             complement(23794..25290)
                     /locus_tag="ACHA1B_000537"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFM8701328.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(25484..27106)
                     /locus_tag="ACHA1B_000538"
     CDS             complement(25484..27106)
                     /locus_tag="ACHA1B_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFM8701329.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(27434..28747)
                     /locus_tag="ACHA1B_000539"
     CDS             complement(27434..28747)
                     /locus_tag="ACHA1B_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFM8701330.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(28992..29216)
                     /locus_tag="ACHA1B_000540"
     CDS             complement(28992..29216)
                     /locus_tag="ACHA1B_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701331.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(29236..29658)
                     /locus_tag="ACHA1B_000541"
     CDS             complement(29236..29658)
                     /locus_tag="ACHA1B_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM8701332.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(29800..30510)
                     /locus_tag="ACHA1B_000542"
     CDS             complement(29800..30510)
                     /locus_tag="ACHA1B_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase beta subunit-related
                     protein"
                     /protein_id="HFM8701333.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(30528..31025)
                     /locus_tag="ACHA1B_000543"
     CDS             complement(30528..31025)
                     /locus_tag="ACHA1B_000543"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8701334.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(31062..31514)
                     /locus_tag="ACHA1B_000544"
     CDS             complement(31062..31514)
                     /locus_tag="ACHA1B_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFM8701335.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(31649..32254)
                     /locus_tag="ACHA1B_000545"
     CDS             complement(31649..32254)
                     /locus_tag="ACHA1B_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HFM8701336.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(32704..33324)
                     /locus_tag="ACHA1B_000546"
     CDS             complement(32704..33324)
                     /locus_tag="ACHA1B_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM8701337.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(33326..34195)
                     /locus_tag="ACHA1B_000547"
     CDS             complement(33326..34195)
                     /locus_tag="ACHA1B_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HFM8701338.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(34218..34625)
                     /locus_tag="ACHA1B_000548"
     CDS             complement(34218..34625)
                     /locus_tag="ACHA1B_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HFM8701339.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(34644..35933)
                     /locus_tag="ACHA1B_000549"
     CDS             complement(34644..35933)
                     /locus_tag="ACHA1B_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFM8701340.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(35960..36262)
                     /locus_tag="ACHA1B_000550"
     CDS             complement(35960..36262)
                     /locus_tag="ACHA1B_000550"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM8701341.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(36287..38380)
                     /locus_tag="ACHA1B_000551"
     CDS             complement(36287..38380)
                     /locus_tag="ACHA1B_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFM8701342.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(38869..39633)
                     /locus_tag="ACHA1B_000552"
     CDS             complement(38869..39633)
                     /locus_tag="ACHA1B_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HFM8701343.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(39744..40613)
                     /gene="mdcB"
                     /locus_tag="ACHA1B_000553"
     CDS             complement(39744..40613)
                     /gene="mdcB"
                     /locus_tag="ACHA1B_000553"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046917 - triphosphoribosyl-dephospho-CoA
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0019361 -
                     2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HFM8701344.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(40638..41714)
                     /locus_tag="ACHA1B_000554"
     CDS             complement(40638..41714)
                     /locus_tag="ACHA1B_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFM8701345.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(41738..42331)
                     /locus_tag="ACHA1B_000555"
     CDS             complement(41738..42331)
                     /locus_tag="ACHA1B_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HFM8701346.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(42335..44011)
                     /gene="mdcD"
                     /locus_tag="ACHA1B_000556"
     CDS             complement(42335..44011)
                     /gene="mdcD"
                     /locus_tag="ACHA1B_000556"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HFM8701347.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(44001..44300)
                     /locus_tag="ACHA1B_000557"
     CDS             complement(44001..44300)
                     /locus_tag="ACHA1B_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HFM8701348.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(44402..46048)
                     /gene="mdcA"
                     /locus_tag="ACHA1B_000558"
     CDS             complement(44402..46048)
                     /gene="mdcA"
                     /locus_tag="ACHA1B_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015451 - decarboxylation-driven active
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HFM8701349.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(46055..46966)
                     /locus_tag="ACHA1B_000559"
     CDS             complement(46055..46966)
                     /locus_tag="ACHA1B_000559"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFM8701350.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            47086..47943
                     /locus_tag="ACHA1B_000560"
     CDS             47086..47943
                     /locus_tag="ACHA1B_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFM8701351.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(48130..48492)
                     /locus_tag="ACHA1B_000561"
     CDS             complement(48130..48492)
                     /locus_tag="ACHA1B_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HFM8701352.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(48681..48863)
                     /locus_tag="ACHA1B_000562"
     CDS             complement(48681..48863)
                     /locus_tag="ACHA1B_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701353.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            48838..50277
                     /locus_tag="ACHA1B_000563"
     CDS             48838..50277
                     /locus_tag="ACHA1B_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8701354.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(50284..52836)
                     /locus_tag="ACHA1B_000564"
     CDS             complement(50284..52836)
                     /locus_tag="ACHA1B_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HFM8701355.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(52950..54281)
                     /locus_tag="ACHA1B_000565"
     CDS             complement(52950..54281)
                     /locus_tag="ACHA1B_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFM8701356.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(54247..55725)
                     /locus_tag="ACHA1B_000566"
     CDS             complement(54247..55725)
                     /locus_tag="ACHA1B_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFM8701357.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(56030..57865)
                     /gene="tdc"
                     /locus_tag="ACHA1B_000567"
     CDS             complement(56030..57865)
                     /gene="tdc"
                     /locus_tag="ACHA1B_000567"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFM8701358.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            58335..59762
                     /locus_tag="ACHA1B_000568"
     CDS             58335..59762
                     /locus_tag="ACHA1B_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8701359.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(59854..60219)
                     /locus_tag="ACHA1B_000569"
     CDS             complement(59854..60219)
                     /locus_tag="ACHA1B_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFM8701360.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(60216..60581)
                     /locus_tag="ACHA1B_000570"
     CDS             complement(60216..60581)
                     /locus_tag="ACHA1B_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HFM8701361.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(60773..61021)
                     /locus_tag="ACHA1B_000571"
     CDS             complement(60773..61021)
                     /locus_tag="ACHA1B_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701362.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            61020..61148
                     /locus_tag="ACHA1B_000572"
     CDS             61020..61148
                     /locus_tag="ACHA1B_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HFM8701363.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            61205..62899
                     /locus_tag="ACHA1B_000573"
     CDS             61205..62899
                     /locus_tag="ACHA1B_000573"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050151 - oleate hydratase activity
                     [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA];
                     GO_process: GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HFM8701364.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            62999..63295
                     /locus_tag="ACHA1B_000574"
     CDS             62999..63295
                     /locus_tag="ACHA1B_000574"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701365.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFLTWLDLLPQMQA
                     FEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLPRGYEKGV"
     gene            63673..64806
                     /locus_tag="ACHA1B_000575"
     CDS             63673..64806
                     /locus_tag="ACHA1B_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HFM8701366.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            64837..65157
                     /locus_tag="ACHA1B_000576"
     CDS             64837..65157
                     /locus_tag="ACHA1B_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HFM8701367.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(65186..65650)
                     /locus_tag="ACHA1B_000577"
     CDS             complement(65186..65650)
                     /locus_tag="ACHA1B_000577"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8701368.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(65781..67034)
                     /locus_tag="ACHA1B_000578"
     CDS             complement(65781..67034)
                     /locus_tag="ACHA1B_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFM8701369.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(67063..67380)
                     /locus_tag="ACHA1B_000579"
     CDS             complement(67063..67380)
                     /locus_tag="ACHA1B_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFM8701370.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(67406..67726)
                     /locus_tag="ACHA1B_000580"
     CDS             complement(67406..67726)
                     /locus_tag="ACHA1B_000580"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM8701371.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(68190..69605)
                     /locus_tag="ACHA1B_000581"
     CDS             complement(68190..69605)
                     /locus_tag="ACHA1B_000581"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFM8701372.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(69622..70938)
                     /locus_tag="ACHA1B_000582"
     CDS             complement(69622..70938)
                     /locus_tag="ACHA1B_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFM8701373.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(71088..71786)
                     /locus_tag="ACHA1B_000583"
     CDS             complement(71088..71786)
                     /locus_tag="ACHA1B_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="HFM8701374.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT        21075 a        15249 c        12171 g        23441 t
ORIGIN      
        1 gtttcctctt ctgtttgggt gataactgcc gctttttctc cttttagaga aaccaaaatc
       61 tcagctagta ttttcaacaa ttcttcagag gatcgaaaag agcggtattc gggttctttt
      121 ccttgcggtc ggatcgatac gatgtcgatc ttctcttgat ccacagcata ggttttgaaa
      181 agctctgtga ttgctccgct agaacggtaa ctatttctaa gatcataccg atggatcggc
      241 agatggtagt cgtcgaaaca acgcataata tcagcaaaag tagtggaaga attaaagatt
      301 gcctgattct cgtcacctac taaagtaaag tgagtttttg gaaataattc gatcaataga
      361 cctaattgtg ccagggtata atcttgtact tcatcaatca atagatagcg aaatgctggt
      421 acatttacct tttcaacaag taaatgacga atagctaata taatgactgc ttcatcaaca
      481 gtacgtgtgg gttgccaagc ataagctgag ccatatcgtt tttcataaat tctttcaaac
      541 aactgatgct catccaccca tgccatttct tcgatttgtc tggttatttt tcgatatttt
      601 ttttgtaaaa gtttccttgc ataagctaca atactttgtt ccgaatcatc agaaatcaat
      661 ttaccgaata attccaactg cctatcttct gtcaacgaga gtacctgatt ctgcacagca
      721 ggactttttg cttgtttcaa aagatgattc ttccattcgc tcatcagtgc ctttttcgtt
      781 gcttgaagcc tatcgatcaa tttaggatga gcaggaactt tctcatatat tttttcgatc
      841 gtttttttag aaaggactgt ttttccattt ttagtaagtc cacggataaa attcggatga
      901 tctaaaaaca aaggatctga ttgttttaga ttatcgataa actttttgct acgcaaacgt
      961 tctgtctgct ccgatacatt ttctcccgtg atacgtttga aataagcctc ttcaccttct
     1021 atttcctctg ctgaaagctg tgaaaccagc tgtatgatgg ttagattcag tggatttctt
     1081 tcacctaatg atggtaggac attcgaaata tagtcgataa accgatgatt aggtgataga
     1141 atcagcaagt catcggatgt catcgtatct cgatataaat agagcagata cgcaatacgc
     1201 tgcatgatag cagaggtttt accacttcct gctacgccat ttaccaagat attttgactt
     1261 ttcacatccc gaatgattgt gttttgttcc gattggatcg tagcagtgat agccttcatt
     1321 tcattggtct catcttggcc taagacttct aataatacgt catcttgaat agctacagac
     1381 gtatcaaaaa acttgaccaa acgatctctt tccaaaagaa attgtcgtct ttctttaata
     1441 accgtatcga ttttattttg acgaaccgta taagaagatg gaccaatcat gttattgtaa
     1501 aaaagttcgg caattggtga acgccaatca taaacaagat tttcatctgc atcatctgtg
     1561 aaatttgctg taccgatata aaaggattct tttggctcat tatccagaaa gtctacaacg
     1621 acttttccaa agtagggact tttcaataaa cgttcgatct ttgctagctg attttctgcg
     1681 tttttctgtt tgatattcat ctgatcgatt tctctatttt tcatttcaat catcgaaaaa
     1741 gtatccaggt tatctaagta actgtcaaaa ttcaatcgaa gctcgccagc catttctttc
     1801 aacgactggt ttccttctat ttttgccgta tccatcgatt cccgcagttc gtttttttta
     1861 tcaattagct tttgatacac gttcttcaga tatgcttctt ctaactgttt ttgtgtgttg
     1921 accatacaca ttctcctctt tttttaaagt ggtggaaccg attagtttac ctcttttaag
     1981 agtcgaatgc aagcttttta acgagtatca tttgttagga tatatcagtt cttcaggtcg
     2041 gacagtttga tataaagaaa atgcaccatc aaggtttttt acgtggtagc cagactgctt
     2101 caagattctt tccgctagat agctacgtaa tccgctatga cagctgacga tatattcttg
     2161 ttggctgtct aattcattta atcggtcccg aagttcattc aaagggatat gtttggcttc
     2221 cttgaatttg cccttttcca attcttctgc tgttcgcaca tctaataaaa tttttccttt
     2281 tgctagttct gtcggcaatt catgccattg tacggtttca ctaagccctt ctgcaatgtt
     2341 cattgctgca tatcctagca tgtttactgg atctttggct gagccaaatg gcggtgcata
     2401 cgtcaattct aattccggta aatcgaagat cgtcaaatgc cctttgattg ctgttgctaa
     2461 aatatcgatc cgtttatcca caccttttgc cccaacacct tgtgcaccat aaatctcgcc
     2521 agtctctgga tggaagatca acttcagtaa aatatctgtt gcttctggat aatagcttgc
     2581 atgatctttt cctgatacat gaatgacttc aaaagacagt tcgttttctt tggctgttct
     2641 ttcacttaaa ccggtggatg cggcagtcat tccaaacgtt cgtataattg ctgttccaat
     2701 accgccttga tttcttcgag aaattccgga aatcgtgtcc gcaacttgtc taccttgacg
     2761 attggctggt gaagcaagag aaataagtgc atcttttcca gtgatttgct gttttacaac
     2821 gatagcatcc cccaccgcat aaatatcagg aatattcgtt tgataacgtt cgtctactag
     2881 gatacccccg cgtatgccta attcgattcc agcggtcact gctagctggt tatcaggacg
     2941 aacaccaatg gataaaataa ctaaatcagc agggatggta cgcccatcat ccagtcgcaa
     3001 tcgtttcccg tggtcttcaa atccagcgac agcatgagaa gtaatcactt ctactccttg
     3061 atgagacaat tctttttcta taaaagctgc catttcttca tccagtgttg gaagaatatg
     3121 tggtgcttgt tcgatcacca tgacttctaa acctcttctt tttaggtttt ctgccatttc
     3181 caatccgatg aatcctgcac caacgatcac ggcacgcttt ggctgttttt ctaatgcatg
     3241 catcacttta tcgatatctg gtacatttct aatagaaaaa acattgtcgg cttctgttat
     3301 ccctggaatc gatggaacaa ctggttttgc accaggagat aaaaccaatg catcgtactg
     3361 ttcaatgtgt ttttgaccct catgtacgac ttctaccgtt ttgttttcgg gaaagatggc
     3421 tgtcacttca tgatttggac gcacatctaa acaaaaacga gcggataatg attctggcgt
     3481 ttggacaaga agattttccc gttcactgat ttctcccgaa agataataag gcaagccgca
     3541 atttgcaaaa gaaacatacg gtcctttttc aaaaacaacg atttctgcat cttccattaa
     3601 tcggcgaagc cgtgtagcag cagacattcc acctgctaca cctccgacaa taacgatttt
     3661 catcttattt ccctcctact gttcgatcaa accattgatt catgccacca cgtacattca
     3721 ctacatcata accagatttc tttaattctt tagctgcttg tttactcctc atccctgatt
     3781 gacaaatcac atagacggtc ttttctttgt ctccatcata tctgtttata ctttgtaatg
     3841 gaacattttt agctcctttt atatgcccgc cccggtattc tgcaggtgtt ctaacatcaa
     3901 gtaacgctgg attttccaaa agcttttcct ttaattctgg gactgttatc gattttattg
     3961 attgaaatag caaattcatt ttctgcacct catttacatt tttataaata cctcatgggg
     4021 tatattaaac aggagcttta ttaatatgtc aaccagaatg actcttcatt tttttcacta
     4081 ctttttatat ttgcataaaa taccgataag gggtattatc taattataaa aatagaggag
     4141 aatgtgttat ggagattgat aataaaaata tcctgaaccg tttgaaacgt acagagggac
     4201 aaattcgtgg tatccaaaaa atgatcgaag acgaaaaaga atgtatggat gtcatcactc
     4261 aattaagcgc tgttcgttct agtattgatc gcgtaatggg catgatcgtt gcagataatc
     4321 tgaaaaattg ctttgagaaa cctgatagta atccagaaga acaagcggct aaactagaac
     4381 aagcgatcaa gatgattatt aaaaagtaaa ggaatgattt caatgaaagt cgttttccat
     4441 attgatgaat tagaaaaatg gtcagaaaca gggaaaaacg taaaaaacct gataaaagct
     4501 tctccagaaa cgacgattgt cgtatctgta aatggcatcg cgattaccgg ttatctagac
     4561 tctgccaatg cagaattctt agatttgcaa ggagtcgttt ttcacgcttg cgccaatgct
     4621 atgcgtgcta atcatatttc agaaagttct ttacctgaac aagtaatcgt tgtaccagca
     4681 ggtgtccttg atttagttga actgcaatcc caaggttatg cttatatcaa gccttagtca
     4741 gtagaggttg cgacagaagt gatcagcttc aagaaatttc ggcttatttt tcgaagaagc
     4801 tacttctgga aaaccgtgaa tcaaaggttg tgaaaacgct gtcctgcatc aagtaataag
     4861 aacagccaaa caaaaatagc ttctcatatt tttcgtttgg ttgggcttat taccgcagat
     4921 gcaagctttt gaacaccgtt taaggaagag gttgtgaaat cagcggtttg acctaagtat
     4981 tagagaaaaa aacgggaaaa tagctcctca tattttgccg ttttttgagc taataccgaa
     5041 ggtcagctga ttgaacaccg tttaaggaag agattgtgaa aaagtcgctt agtttcgagt
     5101 attaagaaaa attttgtgaa aatggatttc tacatttttg cataaatttg gcttaatacc
     5161 gagaaactgg cttttgaata ccgtttaagg aagaggttgt aaaatcagcg gtttgacctg
     5221 agtattagag aaacaaacgg aaaaatagct gctcatattt tgccgttttt tgagctaata
     5281 ccgaaggtca gctgattgaa caccgtttac caagaggttg tgagcctacc atttaactcc
     5341 gaatcacaag aaataatttc aaaaacaact tctcctgttt ttggttcggt tggcttatta
     5401 tcgagaagta gctactggga gtctatttat caaaaaaagg aatgcgacat aggtcacacc
     5461 ccttttttat tttctttgaa acatctttcg gtactcgaca gcatacaaga caaaagattg
     5521 taaaagaccg taagtgatga cggcaaaaat gactctcacc cacagcgttg gtaattctgg
     5581 gaaaagcagc aaaaggatca tgccaacata gatgacagca gtcgctactt tgccatacca
     5641 cttcgctcca cttaatttga tatttttaga tagcccgatt aatccagcta caaacataaa
     5701 gccttctttt atcaagaata gaccaaacaa cagccaaagc cacggtcgat accatgccat
     5761 agacaaaatc agaaaaagtt gtgtcaattt atctgcaaac ggatcaagca ccttccctaa
     5821 gtctgttacc tgattatatc tccgagcaat gaccccgtct agataatcag acaaacctga
     5881 gacaacaatg accgctcctg ctatataaaa tgactgtctc agcacaaaat aaagataaat
     5941 cggcagcaaa aaaatacgga atatcgataa aagattcgga atcgtttgta tttctttacg
     6001 ccagtctgtg cttaatttca ttttatcgcc ctacctcctc agcactcttt tctttttatt
     6061 ttagcttaca cggggaataa aaccaatgat ttcactgttt ttatttttct ttacagacac
     6121 tgatattatg agctaatttg agataatcac ttgctgtttt catcgtttac tcttctttct
     6181 tcctgtcgtt tgcgcatttc ttttactagt actttatgag ctttttttga tcctcgctct
     6241 aggtcacgct gccgtttacg tgttttataa tcgataaaca gactgtctaa atcgtaacct
     6301 gtcgggtaca gatcttctgc tgaacgcacc agacgaacac gctgacgagg cacgtggatt
     6361 atttttttgt ctaaatatac atcaatcgta tcttcaccta tatcttcata aactaacgct
     6421 tctttttggt attcattgac aaatatccga tcaccttttg caaagagctg acgttctttt
     6481 ttattctcct tcctatttgt aactgctgtc ttaggaagaa attctttttt ctgtgtccga
     6541 taggcttttt ccgccaagta acgctctgct tgatggatca atttcatcga catatccatt
     6601 ttatgagcaa tccacaaagc ttggctttct cctgtttctt ccaacccgca actgatattt
     6661 aggacgaagt gcttcccgat cgaaagccat agcagccggc acaaaatctt catgatctcc
     6721 ggcgaatttc ttgatttctc cataatgggt cgtggcaatg atcaatgccc cttgctcata
     6781 catagattcc atgattgcga tcgctagtgc agccccttca tttggctctg ttccactgcc
     6841 aatctcatct aaaagtacca acgtattcct ttttatcttt ttcaaaatag cagcgatgtt
     6901 ttgcatatga ccagaaaatg tactcaacgc attttctaaa ttttggtggt caccgacatc
     6961 gacgaaaatc tcatcaaaga cagcaagctc tgtcccttct tttgccggaa cttgcatacc
     7021 gaacatcgcc atcaaagtca ataaaccgac tgtcttcaac acgactgttt tgcctccggc
     7081 atttgctccg gtgataatca agcctcgata gtctttaccg atttcaacat ccaatggtac
     7141 cgcatgctca ggtaaaaatg gatgtctgcc ttgcttgata atgatatgtt ccgatttatt
     7201 gattctaggt gtgcttccat tgatttctcg gctaaatttt gcccgagcaa agatgatatc
     7261 taacaccgtg atcgtttcga tcaataaatc gatcacttct tcgttttctg cgatagcacc
     7321 agtcaatgcc gccaggactt gatattcttc actgatttct tcagctttta acaactgata
     7381 gtgttcattc aatttagaaa tcacagttgg ttcaataaaa accgtcgttc ttttatttga
     7441 ttcatcgata atcgttccat ctattttatt tttatagctg gctttgatag gaatcgtata
     7501 gtattcgcct ttttgaacaa tcattgcttc ttggatcatt tctttgtttt tcggatgacg
     7561 caagaatttc agtaattttg actggatttc tttttcgatt agttgtaatt gtttgcgtac
     7621 tttacgcaaa ttacgtgacg cgtcgtcact gactttatta ttttttattt tctggtcaat
     7681 caactcttct acatttatca aatcaggaag atgtttgcta taagcaaaca acaagggtgt
     7741 ctggtattga ttcttatcaa aaaactttgt gatcatccga ctgcttctaa gaaaatccgc
     7801 atattcgatc aaatcggttg gctgcagaat caaccctttt ttgacttgtt ctgtcagtgc
     7861 atcgatcctc ggcaacccca taaatggaac atgctgactg ctttctaaga tcaagcgtgc
     7921 ttctcttgtt tcttcttgac gatccaagac agtttgtagg tttgtcgaga ccgtcatatc
     7981 gctgattcgt tttttgctat agtttccaat tgctcttgct tggatttcct ttttgatccg
     8041 atcaaattgt aattgactaa tcatttcgtt gtccatattc tctccttttc ttgaagagat
     8101 acctgtccca aaataaataa gggcctagag ataaataaaa ggatagaaca cagcttaaaa
     8161 aagtcatgtc ctatccttat tagaatacaa agatattgtt ttcctgacag gtaccgtttc
     8221 ataagcacac caaataaact ttgtttattg gctattcgac ttactgatta gataccagct
     8281 acactcacaa aacatacccc attcttctag gtcttattta ttttccactt aactatagca
     8341 agacacattt tggttgtcaa actttagtat gttttataga tttacaccat taatgaatag
     8401 acacctaccg cgataattgc tccgatcatt ggacctgcga ttggtaccca tgaatatgcc
     8461 caatctgaag ttcctttatt agctattggc aataccgcat gtgctaatcg aggaccaaag
     8521 tcccgagcag ggttgattgc atatcctgtt ggccctccta atgaaagacc gatggctaag
     8581 atcaatccac ctacagcgaa tacgttcgtt ccaggtgcaa attcgttttg tccaaaagct
     8641 agcaacccaa gaactaatac aaatgtacca attaattctg tgatcacatt tgctggataa
     8701 ttccgtatag caggacctgt tgcaaacgtt cctaaaatcg cgctttcatc tttcgttgca
     8761 ttccaatgtg gcaaataaga aagccaaaca agaatggccc ctgcaaaagc tcctaaaact
     8821 tgcgcaatga tgaaaggaac gacaagattc caactaattg cccctgtcat cgccatagct
     8881 agagagactg caggattcaa atgagctggg cccatgaatc cagaaatata gacagccatt
     8941 gttacagcga gtccccaacc aaatgcgatg acaatccagc cagaagcctg tgctttactt
     9001 ttgtttaaat tcacagccgc acacacacca tctccaagca aaactaggat cagtgtccca
     9061 ataaactccc ccatgatttg agtcatatca ctgttcattt atttctcccc ctttagttcc
     9121 cgcagatctg attctgcaat caatgcttct aaacgtttag tctgttgcgc cttctcctct
     9181 tctgtccatt caaaatatcc agcaattgca tcgatcacag gttgcttgat ctcatcaagc
     9241 tgatctcgtt caaacaacag atgatttgta cgacgaatga gataatcgcc tggggccaaa
     9301 accatttctt cttctaaacc ataacgtaac cgagctgact cagcgagact caaaccagga
     9361 taaggtgcca tttcttttgc taattcaaag atacgtcggg cattagtccc gtaaaaatca
     9421 gcgatataag tagcatcttc ttcctctaaa ccggctgcta ctccttcttt tgctaattct
     9481 gtcactgttt cttctaattt agttggatcg aagtttccac ctgaaatctg atatttttta
     9541 gagtcgattt ctttcgtctc tattccgtat tcttctttta ataattggcg tatcaatcgc
     9601 aaagctcctt ctgccatctt acggtaatcg gtgattttcc caccagataa agtcagcaaa
     9661 ccatctggtt ctctttctaa agaactacct ctggaaatcg tagaaggtgc tttttcatca
     9721 cggctgtttt ccaaatggtt caacacgtct tctacttcag cacgagaaac tttgttttcc
     9781 ttatattcac ttactgtatc gacaacttta ttgaagctct tgtctgaaat cgatccatta
     9841 tctccaccat tgtaatcaga accagaatta ccaatcaaca gtggacgaag tcctgcccag
     9901 cttgcttcga tatcattcaa tgtgatattt gcttctggat agcgatgatt gatcacatcc
     9961 aatagataat ctacatcttc ttgtgtgact ttcggatccg taaaatctcc ttggtaatcc
    10021 gtatctgtcg taccaaagta agtcttgttt tctcttggaa tagcaaaaac catccgccca
    10081 tcttgctttc ctgtatcgaa gtatgtgggt tgcggtacag gcagtttttt cgcatctaca
    10141 actaaatgga tccctttagt tggacgcatt ttaggagaga ctggacgcgt aaaattcaag
    10201 tttcgtactt tatctaccca aggaccactc gtattgatca ctaattttgc tttgatttcg
    10261 atcacttcat ctgtcagcag gtcacgagct ttgacgccaa cgatttgatc gccatcatat
    10321 aaaaagccaa ccgctttcat tttacttact agataagccc catcttcggc agcctttttg
    10381 atattatcaa tcactaaacg ggcatcattg ttgcggaaat ctagatagac acccgcgcct
    10441 tttagccctt cttttttcaa aaacggttct ctttccaata cttcttctgg tgtcagcgta
    10501 taattctcat atttggttcc tgtcacattt gccagtttgt cataaaggtc cattgctact
    10561 ttgaccgaga acatattgaa ggttgttgct ccttcgccct catagattgg caaaagcatt
    10621 ggatctggtt ttgggatgtg tggggcaata ctttgtacga ctgcacgttc accaactgtg
    10681 tcagctacta cttccacatc aaatgtcttc agataacgaa taccgccatg aacaagtttg
    10741 gtcgagcgag aggaagtccc ttctgcaaaa tcctgcattt cgatcaatcc tgttttgatt
    10801 cctgatgctg ctgactggac tgccacaccg gcaccagtga ttccgccacc gatgatcaac
    10861 agatccaatt cttcttgctg cattttttga atgctatctt gtcttgtctt gtttgaaaac
    10921 atatggattt cctccttatt caaatgcttg ggtagctttt actgcttttt tccaaccgtt
    10981 gtaaagtttt tctcggcgct cttcctccat ttgaacttca aatagcttgc cagcttcata
    11041 aaattcgcgg atctcgtctg tatctttcca ataaccgaca gctaatcctg ctaaaaatgc
    11101 tgcccctagc gccgttgttt ccaagttttc tgctcgttgg atcggtacat tcaagatatc
    11161 tgtttggaat tgcatcagat attcattgtt tgctgcaccg ccatctactt tcaatacagg
    11221 aatcttgatt ccagtgtcat cttgcatcgt atcgatgata tctctcactt gataagcaat
    11281 cgactgtaaa gtagctttaa tgatatcttc ttttgtcgta ccacgtgtca agccaaacat
    11341 agcccctcgt gctgcctgat cccaataagg agcacctagc ccaacgaatg caggaacaac
    11401 ataaacctca tcttcgcttg tagagcgttt cgctgcgtct tctgaatcgc tagctttttg
    11461 caacatttga agtccatctc tcagccattg aatcgaagaa ccagccacaa aaatacttcc
    11521 ttctaaagca tagtaaacct ttccatttat gccgtaacca attgtcgtca ataaattatt
    11581 tttggataat tgcggttttt caccggtatt catgacaata aatgaacctg taccataagt
    11641 attcttgacc atgcctggtt cgaatgccat ttgtccgaat aatgcggctt gctggtctcc
    11701 tgccatccct gaaattggtg cttcgcttcc ataaaaatga taaccttgcg tataaccata
    11761 aacttctgag ttagaagtga cttttggtaa catcactcga ggaatattta gtaaatctaa
    11821 aatctcctga tcccaatcta gctgatggat attgaacaac atcgtccgac tggcattcga
    11881 gtaatcagta acatgtgctt gtccatcggt cagtttccat actaaccaag aatcgatcgt
    11941 tccaaacatc aattcgcctt tttcagctcg ttcttgcgcg ccttctacat gatcaagaat
    12001 ccagcgtatc ttcgttgctg agaaataggc atcgatcact aaccctgttt tttcgtggaa
    12061 aaattcttga tagccttcat tttttaagtt atctgcaatt ccagctgact gtctggattg
    12121 ccaaacaact gcatgataga ttggacgtcc tgtatctttt tcccatatta ctgttgtttc
    12181 acgctggttc gttatgccaa tcccagcaat ctgatttggt ttgatccctg attcgatgaa
    12241 cgctccggca ataactgact gtacagaatt ccagatttca tttgcatcat gttccaccca
    12301 actttcttgc gggaaatatt gcgtgaactc tttttgagaa ctgccgatgt gtcttccttt
    12361 cttgtcaaag ataattgctc gtgagctagt tgtaccttgg tcaatcgcca tgatatacgt
    12421 tgattctgtc attgtgattc cctccattat atgcaaacgc tttctttaac tactcttatc
    12481 atactactgt tttaaaaaaa gaaactgtca aaattttatt ctttttttct ttttttgaca
    12541 gttttttatt atgaagctat tttttaatca attcttttct tttttcagcg tctctattct
    12601 tcttttcaat cgaataatgt cgtaaggtga cgcaaattct gacagataat attcacactg
    12661 ttttttgttt ctctggcaaa atgtgatcac caaatcatat tctttacctt cttcataact
    12721 tccaatctca ataccgccga ttcccctcag ttctctgatc agatattgtt gaaaagcaat
    12781 acgataaatc ggcagacttt ctaaatcgat tccaatcact actggttttg caatataaaa
    12841 atcgatcatc aaaagaacat tggcatactg gatcatcagg taactaagct cactatcttc
    12901 agctcttttc ctcggcaatt gctgcaccgc tgtttcctgt aatttcgcca gtaactgtgt
    12961 taaggaatgc ccgagcattt tctgctgctg ttccaaaagc cgatcacgct catagacttc
    13021 gatctttcca acaaagaaaa accattcatt gttgatctgg gaaatttggt agcctactgc
    13081 cttttcttct ttgattttca aacgacgagg acgataatgc cataacatcg tttcccgaat
    13141 gtaagtatct aaaacagcgg ttggtaactt tttgctccgt gtcaaatcat actgataaaa
    13201 tatttcttcg tctactatcg aaaaagaaac aaaaaagctg taaaacatca ttgtttcgta
    13261 tacattcagt tctgctgctg ttcgactaag atgcatcacg atgattggat cgattgcttg
    13321 ataaagccgg tccgactgat agagtaattt cttttctttc aaagttgcgt acgtactttt
    13381 ttcattcaat agtctttttt tcgtaatccc gagccagcaa gcaatctgtg cttctgctga
    13441 tgccgtaaac gttgtttcta atacacggtc caatcctaga atgaacggtc ttttttctgg
    13501 tgtattttgc aaaaaaagcg gtcgctgatc ttccgggata tattggaata gttcataata
    13561 aaaatatcgt atctgtagct cttctccgta taattgaccg tttttgattt gtaatccaaa
    13621 ttcctctaag agctggttca attctttgat ctttcgaaaa acagaagact cactgatatt
    13681 aaacgctgtc gctaatcgaa cgatggatac ttgctgatgt tctaataaat agacgagcat
    13741 cttaaacttc aagctttcct gcaataaaaa caatagaatt ttttccaaac ttacatcttc
    13801 gtccaacaca agcagcgcct gatactcatt tcgctgtact tctacttttt tttccatcat
    13861 tcggccaatc aattcaatat cttccaaata ttgatcaaac gaggcttttg acagttggac
    13921 atgctctctc aaaccattga tagaggctgt tcccccttgc agaacaaggt ttcgcaaaat
    13981 caggatctgt aactgctctt ttctttctaa taatgcttca atcttcatag gcagtattcg
    14041 ccacctttga ccacaccata tctggcacac ggtattctgg ctggaaaaat agctcatgtt
    14101 cttctaactg ttcaaacgtc catccttctt ctactgcaat tgtcagttgg tcaagaaggt
    14161 ggaacatctc ttttttgctt tggagctgtg ctccaagaat ctttttttca gaatcaaata
    14221 gaaatttgag tttaactttg ctttgattta ttgctgtaag cttgtagtct acgtatcctg
    14281 tttcaatttt ttggggataa aaaatgctct cttcttctgt caaacctacg cttcctaaga
    14341 aatagccaaa ccactgattg ccgactggac gataggttcc ctgatccttt gtctgtgagc
    14401 cactaattgt cttgctgaca tttcgtgctg tacggacagc gttatttact agagaaacat
    14461 acattttttc atttgttgga cgaaaagtta cttggatcgc atcgccaatc gcataaacgt
    14521 ctttttgaga cgtttgcaag tagtcatcta cccagatcgt tccatcatca ttcaatgtta
    14581 attgttcttc ccacatctga ttgtcgggac gagaatgatt agccagcaaa acaagatcat
    14641 agttctcctt tcttttttcc gtctctacaa tagcggtttc attttcggtc aaagacacaa
    14701 cttgttcttc taaaaaaagt gaaagccctt gatttttcat ttcctttact aacggttctg
    14761 tcatttcagg atctagataa cgaaaaagaa ttgactttcg gctttcgtaa agatggattt
    14821 gtttttttct tgatgccaac ccttcagcta tttcgattcc tgcttgtcct gcaccaataa
    14881 ttgcaatttt ctttgcattc atgatctttt gctgaagagc cgttacgttt tgtatctttt
    14941 taactgggtg aataagcgtt gattctgcag aaatatttcg aaacttttga tttgaaccag
    15001 tcgctagaat caaacgatca aaatccaatt tttttcctcc tgctaaaacg actttttttt
    15061 ctttcaatcc tattactgtc ttttctgtgt aaacatggat tcgatagcgg tcagtcagtt
    15121 cttctttcgt gatccaagaa agttgttttt cactggtaac ctttcctttt aatatcaaat
    15181 tgaacccgct gggaatccat cctaacttcg attgcttttc aatcaaatat atttcacttg
    15241 ttggcatcaa ttggcgaaga taaatagccg catgaatccc tgcaaacgac ccgccgacaa
    15301 ttacaatgtt catctgcatt cctctttctt ataaggtgtt ctactgctaa cttctcaatc
    15361 agaaaacaca gtattcataa ctcgctttca accttatgat acatagcgat gcagcagaat
    15421 caaccctctc catcataccg tgttctaggt ctgcttctca ataatgtact agtggaccta
    15481 attgaagagt atcatttctg aagagatgtt tcaaaaaatg tactcttata aaagaaaaaa
    15541 actcgccttt tacgtacctc tgtccaaata ggaaacagaa aagaacgaaa agacgagttt
    15601 tagcgtgtgt aatgtaatag ttagaataga cacatcattt atttttaatt ctttaatgct
    15661 tcaacaactg cttcgcctaa ttgatgagca gattgaggat tttgccctgt aagaagccgc
    15721 ccatcaattt gaaccacttc tgaaaaagct gctccagact gatagtttgc tcctttttct
    15781 ttcaaagcat cttctgctaa gaatggtact tcattcgttg taccatttgc ttcctcttct
    15841 tcattactga acccagtcac tgtacgtcca gctaaaatag attttccaga ctcatctgta
    15901 actggcaaca atcctacaac accgtgacaa acagctgaga ccagcccttc atttcgatag
    15961 atttgtgaag cgactttccc aagatctatt gcttctggaa aatcccacat tgttccgtgg
    16021 ccaccagcat aataaaccgc tgcataatca tttgcatcca catcatcagg acgtaaggta
    16081 tttcccaagg cccgatttct gaaatcttca tcttcataat aggcccaatc gatttcatcc
    16141 atattcaaaa cactttgcgg ttctaaaggt acatatccgc ctttaggact gacaaaatct
    16201 gcatcgatcc cattttttac taatacatca taaaaatgag tcagttcact taaccacaaa
    16261 cctgtaggac gctcgatctt ttcgtacttt tctacatttg ttaatacgat caatactttc
    16321 attttcccat cctctttcta taaaaattgc gttattgata acgtgctttc aagaaattat
    16381 ataatgggct tggcaaataa agctctttat atgcttcttc aaaaggtttc gttacaaatt
    16441 catcctcacg gttttccaat aatttctctg cccagtcagg atcgacgatc atttgctgtc
    16501 caattgctgc aagttctgca tatttcaata cctgctctac atcttcgcga ttgcggatcc
    16561 caccgacacc aactaaaggg atctttcctt gaatcgtgtt atggaccact tcaagaatcg
    16621 atttatcgtt gtatttatca gaacgagcta ttcgatcata catatttaat gaaacatgca
    16681 gataatctag ttttgactca cgtaatcgtt caagaagcca gatcgtgtct tcaaaacgga
    16741 tacctggtgt ttcatattct tctggtgaga aacgataccc tacgatgaat ggttttttag
    16801 catattgttc aaccgctgag aaaaccgttg ttaataattc ttcaataaaa cgataacgat
    16861 tttccaagct accgccccat tgatcctctc gtctattcga atgcggagag aaaaattgtt
    16921 ggatcaaata cgtatttgct ccatgcaact cgattccatc aaatcctgat tcaatcgctc
    16981 tacgtgtggc tttgccaaat gcttggattg tttcaacgat ttcttcttca ctcattgctc
    17041 gtggtgtttc cgcatcagga cgttttgctg caactgcact tgcagataca ggctgttctc
    17101 cagataaagt tgctcgactt gtcattcgtc caccgtggaa aatctgaata atcgcttttg
    17161 cgccttctcc ttggattgct ttcgctagct cacttaatcg aggaatcatt tcatcatgag
    17221 cgatgctgag ttcacctggc cagccttttc cgatatcttg gacatttgca gcaccagtaa
    17281 taacagcacc aagaccttta gaacgttgtt tataataagt gatctcatct tcggtgatca
    17341 ctccattgaa aaagctgagt tgtgtcgtca taggcgacag catcaatcgg ttcttcaatt
    17401 gaactcctga aggtaaagta attgattgat caaattgtga cattgtcatt cctcccataa
    17461 ttcgctctga ttaacctatc gagaatcatc tatcattaaa ccactcgatt agttgtacat
    17521 gcaactaatt tgcttaaaaa attttatttt ttttgtaact tatctgttgc atcattcatt
    17581 gtctgggcta attctttact tgcttcattt cccaaaactg ctttgtatga ctgatgaagt
    17641 tcttcccagc taccatcgac ttccttagca aattggcgtc cttgttctgt aagataaact
    17701 aatgacaagc gaccttcgct aactgttttg acgtatcctt tatattctaa tttttcaaca
    17761 aaacgagcaa tcgttgatgg ggcggaatag agcatttgtg caatatcttt ttgtggtatt
    17821 ccatcttttt cttttaatat caataaaata aaaccataag ttggtgccag acctgtcctt
    17881 ctaaacgctt catcagctaa tttattcaac atgcgatcta gctttttcac gctaaagaaa
    17941 agacattcat ctaacgcttt ttcaattggc ttttccattt catcccctcc attggcgtac
    18001 atatcatagt atgattttta ttttttgtca aaaaacacgg aataatgtcc gcctcctctg
    18061 tctagatttg aaaaaaagaa gtagccatct tcaaagaatt tcggcttgtt ttcgacaaaa
    18121 ctccttctgg aacaccgtga atcagaggtt gtgaaaaagt cgtttagttt tgagtatgaa
    18181 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgaaaa
    18241 actggctttt gaacaccgtt tatatcagag gttgtgaaaa agccgtcctg catcaagtaa
    18301 taagaacagc caaacaaaaa tagttcctca tattttgtcg ttttttgagc taatgccgat
    18361 ggtcagctga ttgtacaccg tttattgaga ggtcgtgagc ctgccgttga actccgagtc
    18421 acaaggagca atttcaaaaa acagcttctc atgttttatg actatggtga cttgtgatcg
    18481 aggagttggc aggagaatac tgtttattcg taaagaaggg gctgtgacaa gacttttgtc
    18541 acagtccctt atttcctttt attataggat ttcgccattt gattggatga cttgtctgta
    18601 ccaatcaaat gattttttct ttaaccgttt ctttgtgcca ttcccttcgt catcttgatc
    18661 aacatagata tatccataac gttttgacat ttgtgaagta gaagcgctga cgatatcaat
    18721 gcagccccac gacgtataac caaataaatc tactccatct ttgatagctt ccttcatctg
    18781 ctcaatatgc tgcttcaaat agtcaatgcg gtaatcgtct tgaacggttc catcttcttc
    18841 tactttgtct atagctccga gtccgttttc agctatgaac agtggttttt gatacctatc
    18901 atataattga ttcaaagcaa ttctcaaacc cttaggatca atctgccagc cccattcact
    18961 tgatggaaga tacggatttt taattcctcc agttattaag tttccttgga ccccttccca
    19021 attttctgga tgagcactga ctgcactaga catgtagtag ctaaaagaaa caaaatcaac
    19081 agggtaggct gctaagattt cttcatcacc tacttctatt tttaagttga cacctttttc
    19141 ttcaaacatt cgttgcgtat acgctggata atatcctctt gcttgaacat cactaaagaa
    19201 caaagaagtt ctttgctgct caattgtttt ttgaatatca tccggatcac aagaatacgg
    19261 aacaagaagc tgatagctga tcatacaacc gacttgtgaa cctttgataa tttcatgaca
    19321 agcttttgta gctaaagcac ttgctataaa ctgatggtgt gcaccttggt atttcgcttg
    19381 ttccaaatgg ggatggtttt cttcaattac tcctacgcta acaaaagggt gatgttttac
    19441 acagttgatc tcattgaaag tcatccaata ttttacttta tttttatagc gtttgaatac
    19501 tgtttcagcg aaacgaacgt aaaactgaat aagctttcga ttaggccatc caccatattc
    19561 tgtaaccaaa tataacggca tttcataatg ggaaagagaa acgactggct caatcccata
    19621 ttttagacat tcgtcaaaca cttgatcata aaaaaataat cccgcttcat tgggtgtttc
    19681 ttcatcacca tgaggaaaaa ttcttgtcca tgcgatagac atccgatagc atttaaaacc
    19741 catttcagca aataaacgga tgtcttcttt aaagtgatga tagaaatcat ttccgtgtct
    19801 tttaggataa taatacttgc tgttgggatc ctgcgccgct tttacttgct gatgcgtcat
    19861 catatgccat tgatctgtcc atttttcttt aggtaaatcg ctgtcgaatg tatacacatc
    19921 agacacagat aatccttttt catctacatc ccatgcacct tcacattgat tggccgctgt
    19981 cgctccgccc cataaaaatc cttctggaaa ttttttcata tcgatccccc taaacttgct
    20041 agttttcttg tttgattatt tttcttatga ctagtaatga tatttttgaa tctactacta
    20101 tttgtaacaa taaccattgt ggtcggatca tatccctctt tgattaattc ttgcaaatct
    20161 acttccatca ataaatcgcc tttacgtact ttttttccat cagatactgc actttgaaag
    20221 tatttgccat ttaaattcac tgtatcaata ccgatatgga tcagtatctc tgctccttct
    20281 tcactgacta ccccaattgc atgtttcgtt ggaaaaactg ttgaaacttc cccgtttaca
    20341 gaactgtaga tttttccgtc cgttggaatg atcgcaaacc cttctcctaa agatccacta
    20401 gcaaatgttg gatcgtttac ttcagataaa tcaattattt cacctgctgc aggagtactt
    20461 aacactatat cctttgagga ttcttcttcg atttcatcct tgtagccgaa aagaaaagtt
    20521 agcatacagg aactgatcat cgctaagaaa taactagcaa ctagccaaac aaatccttca
    20581 ccaatataaa tcgggaaaga caaaatactt cttgtagcaa ctgccaaagc accggctcct
    20641 gcggcaccag ctactccacc aaatatagct ccacatatac aagcaatgta aaatggtcgt
    20701 ttatatttaa gagtcacacc ataaacagca ggttcagtga ttccaaataa tgctgtgata
    20761 aatgcagata aagataaact ttttactttc ttatttttcg ttttcaaaaa taccccaagt
    20821 actgctcctg cttgcgcagc tacggcagtc atacatgctg gacctagcgt atcacgaccg
    20881 tagaaagaaa gattgttggt cattactggt acaagtcccc aatgtaaccc aaaaatcact
    20941 aacacttgcc aaaatccgcc gataacagca ccagataaaa cagggctaaa gttataaaca
    21001 gctaaatatc cagctgcaat cagctgactt gcataatctg caattggacc tacaactaat
    21061 aaaataattg ggaccatcac gatgatacaa atgaatggtg tcaataaatt tcgaatactt
    21121 tcgtgcaagc ttttgcgaat cttaggctca atataagaaa gaacccatac agctaaaatt
    21181 gctggaataa ccgtacttgt ataccttgct agaatcacgg gcatccctag aaatcgcaag
    21241 gttatgctat cactatatgc actgacaatc gtaggataaa cgagagctgc tgcaataacc
    21301 atagcgatga aacgatctgt attgaacttt tttgcagcag tatatgccaa aaatataggc
    21361 aagaaataga aaaatgcatc agctgctgca ttcaaaatga tataagttcc tgattcagta
    21421 gttaataaat tcaaactcgt acataaggcg agtactcctt tgatcaaacc acttcctgcc
    21481 aagacgccta aagtcggggc aaaaacagcg gcgatcatgt ctataaaaga gtttaaaatg
    21541 ccttttttct cagttcctct ctttccacta gatgcatcat cttctagttt catttgtttg
    21601 gataatacgt catacacttc atttactgca tttcctacta cgacttgaaa cattcctcca
    21661 gcttcgacta cagtgatcac accttctagt tgctctacct tctccttatc tgccttctta
    21721 ttatctttta gggtaaagcg taaccttgtt gcacaatggt aaacattgct gacattttct
    21781 tcgcctccga caaatcggac aatatctttc gctaattgtg aatagtccat ttttacttcc
    21841 cccttgttaa ttaatgccgt agcaatcctt cttacaagat aagtatagtt cttagaaaac
    21901 ggtttctcca ttcaattagt accccttcta atagcgaacg aaactgtaca atagtgtgta
    21961 tggtttactt agccgagcaa atcactcact gcttgaaaga aaacaagtat atcgtttctc
    22021 ttatagtcaa aggagacaaa aaaaacacgc ttgatcttcc tttgctgatg tataagtggt
    22081 atctcaagct gatactctgt gatttttgtt tctacttggc ttttgataag acagcacaac
    22141 aaagtctcgg catttaacgg aagcataact aggtcagaac taggagagat tagttgctga
    22201 atggaatcta tctttttatg gatttttatt tgattttctt ctttgtagta atgatcaagc
    22261 agttttgttt tctttttttc ttcaactatg gtcagctttt cacgcaaaat ctgataaatc
    22321 tcccaagatt caaactcatc tagaacacta ggtagataaa tcaaatcatc ccactcaaaa
    22381 ataagctctt gctcagtagt caaaattgca tcatattccg ttattttgtt tgattgattt
    22441 ttgaaaagat acactggttc tatccggcat tctttgatcc acatgttcat actttgttga
    22501 atctgttttt ttagtgtatt caaaatacta attggctggt tactaacaat cagtatctcc
    22561 ccttgttttc gaaaaggatt caacgcttcg gcaagataca aaacaaaata agcgctttca
    22621 gctaaattgg gacgtaattg aaaatgtatt gggaagaaac gccgaattaa ataaatttct
    22681 aaaggataac gggagatgat cttttgtaca aaatgattca tggtattatg tccggcatcc
    22741 atcctcgttt tcatttgttt gatatgggtt agcaaaaatt ctgtttcatg gaacaataac
    22801 gaaacaggaa gatctaaaaa acgaataatc gtttgctcaa atgctcttag attcttctct
    22861 atttctttgt ttttttcatc attaatcatc aaataattta actctaatag tcgattttca
    22921 attgcttgtt tttcttgatt ggaaaaagaa tagggtagtt ctgatgataa cttttttgtg
    22981 agggtctcta ccatcggaat aaataatgta tacctgtttg ttttttctaa aagttcttct
    23041 cttcgaagaa tggtcaaaac gagataccga gaaaatcgta tgaagtcctc tcctgaaaca
    23101 atataattat atgatataag aacctctttt aatgtctttt ggacagtcgg catgatattg
    23161 gaaaaaattg tactgatttg ttgaggaaac cttgcgtgtt ggatcaccgt ttctgttcca
    23221 acaagagata agaaaattct ttttgaattt tcttcagcaa tgatttttag tccttttgtc
    23281 gacgaaactt ccagttctaa tttaggattg cgctcgatcc aacgcaaaat cgtttttatt
    23341 tgtaatgata cggctgtttt tgaaagaaag aaaatgtctg ctatcttttg catactgaca
    23401 tacccttttt gaaacaataa gtacgtcaca atagttgaag ctcggaaatc catgctggaa
    23461 tagattttat gtttcgtcac ctcttgtatg atttgctgtt tagtttcaga ttcaattgat
    23521 tctaaaaaat aacctgaacg tttatttgac tggataatga ttttcttctc gtagatagca
    23581 agcatatttt tgatttcagt ttggatcgtt ttcttgttgg tacctaaagc ttcagctaat
    23641 tcttcgcttg ttatccaatg attcttattt cttaatacta caagaatttg gagttgtcgt
    23701 ttatttaagt ccatttgctt acacctcctc tttgttataa acatacagga aaaacctctc
    23761 aaatgacaat agtcacttgc agaggtttaa aaatcatttg aagaaagatc tatattcaag
    23821 gtttttacca ttagactgga taatttgttt ataatattca aaactatctt ttttcaatct
    23881 cctaaagctt ccgctcccat cattttgtct atccacataa ataaagccat atcgcttcct
    23941 catttcccct gttcctgccg atacgatatc gattggtccc caccataagt aaccaatgat
    24001 ttggcaacca tcttttattg cctcagcaat ttcctgaaga tgtattttta gatactcaca
    24061 acgttttgga tcgtggattc gattcaattc atctggtgct tcatctagtc caatgccatt
    24121 ttcaactatg aataatggta attcataacg gtctgtcaat tcattcatga cataacgaaa
    24181 ccctagagga tcaattggcc aactccaagg ttcgggagat ttttccttca aaaagggatt
    24241 atcgaaacca tttgctccgc cagtatctac gcgcatttct gcttcttttt tatagacagc
    24301 gctacgataa taactaaatg caatataatc tgccgtgtta gcttgcaagc actgttcgtc
    24361 tccatctaac attactggtg cacagtcttc ttccttccat gtcctgtaaa tataagctgg
    24421 ataatgccct cggcacatga catcggagaa aaaccatgaa ttgcgtttaa attgcagtga
    24481 accaaataca ttctctggat cacagtcata tgcataagtc gctaatgcag aaaagctaca
    24541 cataataccc atcttagcat ttggatcgat tttctttaat aattgagtag cacgggcgtt
    24601 cgctagaaac atatgatgac aggcttgata aatcactttt tttgttagtg tagcaatggg
    24661 ttcaagttta tctctagcag ggaatgtaac caatccagca gctgcataag gcatacgaaa
    24721 agcattattg atctcattaa aggtcatcca atatttcact ttcccttggt agcgttcaaa
    24781 gacggtctgc gcataaaatt caaaaaagtc gattaatttt cgattttgcc accccccata
    24841 ctctcctacc aatgctaagg gggtttcata atgactaaga gtaattactg gctcgatatc
    24901 atatcgattt aatgtattga ttagtctgtc ataaaatacg agaccagcct catttggctt
    24961 ctgttcgtct cctcttggaa atattcgtgc ccatgagatg cttgttcgaa aagcttttaa
    25021 acctaactcc ttcagtaaac gaatatcctc ttcaaatcga tgataaaaat caatcgcttc
    25081 atgagaaaga taatggagtg attcgtctaa agcaatctcc caaatctttt tttcttcatt
    25141 ccactgaata ctaggatgct ggttcatgat cccgataagc gtatctgtca cattaggtaa
    25201 tttgccgtct tccaaccatg caccttcaca ttgattagca gctactgctc cgccccataa
    25261 aaaattttct ggaaatattt cctgatccat aactatctct cctcgctatc aacaatttct
    25321 tacttgaagt atagctcgat tcatcaaaac aagatattct aactatttcg gcagaagaga
    25381 agaaaaaaat tgaatgctac tcttcatttt taatatttat atataacaaa tacataagac
    25441 gatccccgaa agaaaacact cgttaaccat ctaagcaaac gatttatttt acttccaaca
    25501 caaatgcttc ataaggtcgt aaatcaactt tgccgtctgg taactgtttc agaggataat
    25561 ttgacacaat aacccttaaa gcttcacgtg gaatagtgaa cgtctgcttt tcactggaca
    25621 tattacaaat aacgagccat tgctggtctt catatatgcg agaataggca aagacatgct
    25681 caggcgtctt ttccactaat tcatagtctc cccagacgat gatgtcatgt tttctacgca
    25741 aatcgatcaa tttcttgtac atataaaaaa cagaatcttg atctgctaac gcttcttctg
    25801 cattgatttc tttataattt ggattgactc gaagccatgg aattccagta gtaaacccag
    25861 catgttcacg ggcgttccat tgcataggcg tcctagcatt gtctcttcct ttcgccttga
    25921 ttgattccaa gatttcctct tttgtaaatc cagaagaaat cctttcgtta tacatattga
    25981 ttgtctcaat atcttttgct tccgcgatat catcgattgg gcaattcgtc atgcctaact
    26041 cttctccttg atagatataa ggggtgcctt tcatcatatg gagcaagata gcaaacatct
    26101 tggcactttc ttttcgatac acatcgtcat ttccccaacg agaaacaatt cgcggaagat
    26161 cgtgattatt ccaaaataaa ctattccatc cttcatcacc taaagatgtt tgccatttgg
    26221 ataatacttt tttcagttca gagatactca agggtttcaa atcccatttg tctttgcctt
    26281 cttgctgatc taatcctatg tgttcgaatt ggaagaccat ggataattca tttcttttag
    26341 gattggaata aagtttagcg atttcggtag ttgctcccca tgtttcgcca acagtcatca
    26401 gatttttgtc accaaaagtt gcttgattca tttcctgaag atactcatgc agtttaggtc
    26461 cattacttgt gatttcttta tccggttctt tgccaatcat atcgatcacg tccatacgaa
    26521 agcccccaat acctttatcg atccagaaat tcatcatttg ataaatctct tggcgaacct
    26581 gtttattttt ccaattcaaa tcaggttgac gcttgctata caagtgcaga aaatattgcc
    26641 ccgttttttc atccaactgc caagcagaac cactgaatat tgagcgcaat ctattaggct
    26701 cttttccatt gaccggatca cgccaaatat aatagtcccg ataaggattt tctttatttt
    26761 tacgggcctc aatgaaccac ggatgttcat cagaagtatg attcaccacc agatccatga
    26821 tgatacggat atttcttttc tttgcttctt caatcagttc ttccatttct tccatcgtac
    26881 cgaattctgc catgattgct tgataattac tgatatcata cccattgtca tcattcggag
    26941 actcgtatac tggagaaagc caaattgcat caatacctaa atacgccaga taatccaacc
    27001 tggaaataat cccccgcaaa tctccaatac catcttgatt tgaatcttga aaacttcttg
    27061 gatagatttg ataaacaact gaatggtgcc accatttttg ttccatgatt ttcctcctat
    27121 aaatggatgt ttctattttt tgcttaatca tttattttag tctctctcac taaaaattgt
    27181 aacgctttca aatagctatt gcaccttgtt atcggtaaca gaataaaaca aaaaaacagc
    27241 tgaggaaatt ccctcaactg ttttttgaaa ggattgattt atgcagggaa gaatgctgat
    27301 ttcacaactt ctttataaac ggtgttcact cagctgtccc ttggtattag ctcaaaaaac
    27361 ggcaaaatat aagaaactat tttttcgttt ttttctctaa tactcaggcc agaacgctga
    27421 tttcacaacc tctttatttc acattcaata tccacatgaa tcccacaaat acaaagaaca
    27481 gaccatacat gattggagat acttcttttc ctcttttagc tgctaacatg gtaattggat
    27541 agaagataaa acctaatgca atcccatctg aaatactata agtcaaaggc atgccgatca
    27601 agatcaagaa tgaagggatc gcaatctcta agtttcccca ttcgatttgt cgcaaagatt
    27661 gtgccatcaa tactcctacc ataatcaatg ctggtgcagt tacttgtgaa gtaacaactg
    27721 atagtaatgg agaaaagaac aagcctaaca agaagaaaat ccctgtagta atagctgtga
    27781 tacctgaacg tcctccaacg gcgataccag ctgatgattc tacaaatgca ccaacaggag
    27841 aagtaccaaa taaggaaccc gcaagcatag ctgttgaatc agaagctaaa gctttcccta
    27901 cacgaggcat cttgttgtct ttcatgaaac ctgcttggtt tgctaatcca actaaagttc
    27961 ctgctgtatc aaagaaagtc acaagcaaga atgtcagcac tacgacccac atttgaagag
    28021 aattgatgtc ccctacatgt tttaatgcaa ctaaaaatgt tggtttcaaa cttggtgctg
    28081 cggcaacaat ttcagaaggc attggaatca aacctgtgac cagacctaaa atcgttgtag
    28141 ctgccatccc gatgaagatg ccacctggta cacgccgaac aagcaagata gcagttacga
    28201 ctaatccaaa aatcgtcaac caagtagaac caacgttgag tgatcctaat cctactaatg
    28261 tagattcatt cgaaacgatg atcccacctt cgctcagacc aaggaaagcg ataaatagac
    28321 cgataccgcc agaaatcgca tatttcaaat ctgctgggat cgcatcaatg atcatttccc
    28381 gcagcttgaa gattgtgatc aaaataaaaa tcaaagaagc aacgaatacg ccggctaatg
    28441 ctgtttccca tggaatcccc attcctaaac aaacagaata agcaaaaaaa gcattgatcc
    28501 caagagcagg tgccgttcca attggataac gggctaatac ccccattaaa acacagccga
    28561 tcgcactggc taatgcagtc gcagtaaaca ctgctccttc atccattcca gaagcaccta
    28621 atacagttgg atttacaaat aagatataag ccattgagat aaatgttgta aatcctgcca
    28681 gtacctcacg ttttaccgtg gtgttcaatt tttctatttc gaagtaggaa agtatttttt
    28741 ccttcatctt ccatccccct aaatccgaac attataaata aagtccgtta aaatttcgat
    28801 ttattaataa aacaacgtgt tttatcatat actaaaacaa aacataagta aacaaaaaat
    28861 tcggatttta agcaaaatcc gaacgttcca tctgattaaa tccctttatc tcaaagttca
    28921 tgaacattca ctttggatta caagaatttc tttattgtgt taataaagtt tcttcattct
    28981 agtctcaaaa atcaatagtg tgatttgatt ttaccatttc gtttctgttc ttctttgatg
    29041 aattcttttg tatcgacagg attcagatta tttagtccgc caaaacctgt atcgaccatt
    29101 tttccccagc cttttgtctt cttttttcct gatttgagat tctttgctcg aagcttctca
    29161 ctatgttttg ctcgccgata cttcaaataa ccttctaatc ttcccattag atccactgtt
    29221 tttcctcctt tttattcaat cagacgactc agcttttcct ataacaaaat aattgccttc
    29281 agggtcagaa aaattgaaag tcaagatgcc attgttatct gtgatttctc ctggttcttc
    29341 catgttctcg tagatagttt caaattcatc cgtaaaaaat actaaagaag gcggtggtcc
    29401 taatacctct ggtgaaaact tctgcacaaa tacttttggg aatacgccta attctaattc
    29461 ttttgagatg ctgagtacaa tactcttaaa ttcttctggc aattcgattg tttcagaaat
    29521 ttctgcacca attttttcta caaagaatcg gcaaatcatc tctacgtcat tgacataaag
    29581 catcacacgt gttttttgta tcatcatttg acccttcttt ctatttgatt ttctttcctg
    29641 tctataaact gattccatta tatcacgaaa gcgcaaacac cttgtgtttg atactattca
    29701 agaaaaataa agcaatagtt tctaggattg ctttcctcca caaacttttt ttacaaaaaa
    29761 aaaacggcaa tgaatgccgc tcttcttatt tcgattcttt tataattctg cttctgattc
    29821 atctttggtt agtgtgtgtc taacactagt tacgccaaat gtttgatcga ttttttcctt
    29881 caacgcttcg attgcctgtg cgccacgtgc cgcttgttca gcattgatgg attcaatgac
    29941 cagcaccgct gcttgtgttt cttccgtcag catcgttctt tgggcttcac gccagttgag
    30001 acagcgacag atcgctcctt gttcatcata gtagatgatt tcttccggaa gtgccggagc
    30061 atcggaatct gcacctaaag gcaggaatga ttcgccacct tgggcttttc ctaaatgcag
    30121 atttcctgcg atcttttcga tatcttctcc gccgcaaggt acgccaaaag acaaggaaat
    30181 actattatag atatctacaa gcggattgat tgggaaaaat tcccgttctt gatttgcacg
    30241 tttcagtaaa gcttcaatag aagaacgtgc acctttttta gtcttgaatg tggtaaatgc
    30301 ctgacgccac tgagcaatga cttcgttttg gctgaatgtt tcttctgtaa ggtaatttct
    30361 tgcttctttt gctgcctcat tcaataattg atgatacgtt tcttcacttt cttttgttac
    30421 gtggttatcg ataccattta cggataagat ttcgatggtt gcttcaggaa atacttccca
    30481 gaaattggta tccactatta cttttttcat ctgttcacac ctcttgatta gaataattgc
    30541 ttgatgaata gatagtctgt ttggggatca tctcccatat aaaaaacatg ttcgctgtat
    30601 ttgataaatc cttttttacg ataaaaagcg agcgcaacat cgttgtgttc ccaaacaccg
    30661 agccaaatgg ctgttttttg cttttctttt gctttttcaa tagctgtatc tagtaaaaat
    30721 gtaccgatac cttgatgttt aaattttttt cgtacataga ttcgctcgat ttctaaaaaa
    30781 tgatcagcca tttcctcaga ttgactcgtt cctgtattta gtttcaggta acccgcaggc
    30841 tcttgatcga tactcactag gaaaaaatcg gtttctttat cttttagctc ttctgtaagt
    30901 ttttctagtg cataagcttg tgtcaagtaa tcagctaaat gctccggtga attatctttt
    30961 ccaaatgtat ctgtaaatgt ttcgatacta atttgttgta gtaagtctac atctgaaggc
    31021 gtcatttttc gaatttcgta tttattcacg gcttcttcct ttcaatagat ccttttattg
    31081 ccttttttga caaaattcca atcttcgcta acattcttgc atactttatt taaaagatat
    31141 tccaattgtt ttgcttcttc gtcagaaaga ccatttaatg cgactgcatt ggagtagttg
    31201 ttttctcgaa tgatgaaagg atagatttct gctccttttt tagtcggata gagtttcttg
    31261 atttttttat tttctttatc ttccaaacgt tcgatcatcc cattggattc taatttcttg
    31321 attgctcggg cagtcgttgt acgatctact ttgatcattt ctgctagttt ttcttggatg
    31381 attccaggat tttcgcaaat acgtactaaa taaagatact gtcctcttgt taaatcgact
    31441 tctttgaatt cgatattgct aatagaatct agcgctcggg caatcattcc gatgtctcga
    31501 aggatttcag ccatttcatc ccacctttat tttgtttgta agactagttc acctcttttt
    31561 gttgcaaatg caactatttt caataaaaaa atcaagttct tttttaataa ctagtaaagt
    31621 atattctttt cttcttttac gaaaaagctc aatcacaata gatctggttt ttgttttcta
    31681 aaataagtaa ctgtttcttc gttgttcgct tttctgatag ctttggcaac tcttctatac
    31741 taaaaaatcc catgttggaa gtttcattat tctcaataaa cttggcctct tcaccgtgga
    31801 tcgcacaagc aaaaacaagt ttataatact gaaaaagctg tggaatatct ttttgtttat
    31861 tcgtatcaaa aactgctcgc aactgagtag tttctactgt taatcctgtt tcttcataga
    31921 cttctttacg cacattttct tcaggagaca atcctatttc agcaaatcca ccaggaagtg
    31981 accattcttt cgtccgttta tcttcgatta gtaggacctt gccatctttt ttgatatagg
    32041 cacgaacatc tacttttggt gttggatgtc cttctccaat cgttgtgagc gcttttattt
    32101 cttcgaaagt ttcttttcct atttcactga tcagttccaa tgaaatcgtc cggatctcct
    32161 caaaacgctc tttatcaaat acatcttttc cataatatag accagcttga gaaagtgcga
    32221 gtagtctttt gtattgagcc aacttcttgt tcattctctt cccttctttt ttagcaaatg
    32281 tatgactatg taatcaagta tagaagactg gtttaattac ggcaaataaa tataatgaaa
    32341 tctgcaataa ataaaagaat gttaaaaaac tcgagaacaa aagacattcg acttctctgg
    32401 ggctgtgaat aaatggcgtt caaaagcttg catctgcggt aataagcccc accaaacgaa
    32461 aaatatgacg agctattctt gtctggctgt tcttattaat tgaggcagga cagctttttc
    32521 acaacctccc cactaaacgg tgttctccta ccaactcctc ggtcacaagt cacaatattc
    32581 atcaaacatg agaagctgtt tttttgaaat tgctccttgt gactcggagc tgaacgacag
    32641 gctcacgacc tctcggtaaa cagcgttcaa aagccaattt ttcgatatta agccatttct
    32701 ttgttactta ttgtcattga tttctttttc taatttatcc aatagtggag tgtaatccac
    32761 ttgagtatag tctgttacat caaattcata tagtgttcct aactggaatt tgtcatattt
    32821 tcggtcggcg atgatctttt tgaatgcttc tttcgtaata tgattggtcc ctttcgttcg
    32881 atcttccaat acgtcaccat agtgataatg atccatgata tagctcaaat gacgatctga
    32941 ttcacgatca cgtttgtacc gacgttgcca taacacttca aagtctgctg ttaggcgaat
    33001 cgtgatcacc tgatatccgt atctatctgc taattcttgg agtcgtgctt tttgcttatc
    33061 actaaaagga tactcggaca caatcacttt ctttcctgct tccatataca aatcaagtgc
    33121 tttgtaatag aaaggataaa ctttcgtcct ttcttgttcc gcccgttctt ccaaattgtt
    33181 aaacccgatg gattctgcat agtattcctt gatttcatcg agcgtgatgg catacatatc
    33241 tggaaatcgt tcccgtagtt tattcataag atatgttttt cctgtaccag gactaccagc
    33301 cagaagaatg aaatactttt tcatctcatt tatttcctaa gttaattgga ctttccaagt
    33361 tcataaacag tccaatctta tgcttgacaa tttcttttac tgcttcattt gctggaatca
    33421 cattatggcg aagagacttg ttgatttctg tttcactaaa ggtttcttta gctactttcg
    33481 tccagttgac taaaagctcc gttccaacat tgaatttgcg gatcccgtta ttgatcaatt
    33541 caggataatc ttcttctttc acacctgttc ctccatggat aactaggggg acatcaacta
    33601 ctgcatcgat ttctttcagc aagggaatgt ttacttctgt ttttgatttg aattgtccat
    33661 gattcgtacc gatagcaata gctaatgcat ccacgcctgt agcttctaca aatttcactg
    33721 cgtcttccgg tcttgtatat accttgtcat tttcagcgac atggattcct tcttctgtac
    33781 cgccgattgt tccaagttct ccttctacgg aaacaccgtg cgcatgggca tattctacta
    33841 ctgcttttgt cttcaggata ttttctttga aaggcagatg ggacccatca tacatgacag
    33901 aagtatatcc gctgtcgatt gcttctttga tatcatcaaa gtctcgggcg tggtctaagt
    33961 gcaagactgc atcaaccatt tcttcttctg caatagctgt cattacattg actaacacat
    34021 gcatgccgat atatttagcg gtatcgacac ttgtttgaat aatgatcggc gaacccattt
    34081 cttttgctgc gcctagcata gcaggaagca tttctaggtt atgcgtatta aaagctccaa
    34141 ctgtaaaatt caactcttct gctgtttttg ttacttcttt caatgttgta tacatctttt
    34201 attgccacct tatcttttta tttgtttcct ttgatcgtta cttgttttgc aatttgtcgc
    34261 atctcatcca ttttgcccat gtagtaatcg atcccttgat catcaccagc acgagcagca
    34321 tctgcacgct tctggttata gaggctcatc agttttttat acccatctcc gatcgtctgt
    34381 ttattttcca aactcttttc taaatattgg atggcttgat cgttcacata caattcagaa
    34441 aatttaagtc caacttgttc ataaagtttc gctaatttat gcttatcttg ggtagtggaa
    34501 atctcttgtt tcaattgtgt aatctctgat tgaatctttt cggtcgcttc tggcgatagg
    34561 gctttttctt cttttgccag aacttttttc ggttcttttt cttttttctt aaaaaatcca
    34621 aacatcattt tccctacttt caattaaaat gctttcaaaa ctgggcttaa gatccaggca
    34681 tataagagtg ctgcggctac tgtatctaca tcggttgctg tagcattgtt gaatcccatc
    34741 gaattaaaga tcgttactag caaagcgggc aataatgtaa taaagaaacc atgagcaata
    34801 ccgccaatga tcgctcctcg gcgtccgcca actgcgttgc caaatatccc tgctgtccct
    34861 ccggcaaaga aattggttag cataccaggt aaaatcatcg ctaagccgaa catgggcaaa
    34921 gtaaacatgg caataatcgt accaatcgtt gtcgtaatga aacctaaaat gacagcattt
    34981 gggctataag gaaagaaaac tggacaatct aaggcaggga tcgcatcagg aactaatttc
    35041 atagctatcc ctcgaaatgc cggcacgatt tcacctaaca gtagacgtac accagctagc
    35101 aatacataca cacccactac gaattggatg gcttgtaaaa aggcaaacat gatatagttt
    35161 tgatctcctg ataattcaga agcgaatggt tcgcctgcaa ataaaacagt gatgatatat
    35221 agcgggacca tcacgaccat gacagacaaa taagtatctt gcagaaattc gaaatgtgtc
    35281 ggcaacttga tatcttcgat cgacttttta ttttcgcctt tctcaccaaa aagcttagca
    35341 acaccggctt caaataagta cccgatcgta caaaaatgac ctaaagcaat atcatttgat
    35401 ccagtgattt tacgaatgat cggttgcgct actgccggca tagcaatggc gaaacaagct
    35461 ccgataaaac caccgaccaa gatcaatacg atccctcgca gaccggcaaa atagccaaag
    35521 actgtcgtca tcgttgccat ccataaaatt gcttgaccag ttaaaaaaat gtacttccat
    35581 tttgtgaaac gagccaaaat aatattgaat acaaaaatgg ctaagaacgt cagtgcaata
    35641 tctctaccta aacccaaatc attcattgct tgaccattga tagattcaat agaagggatg
    35701 atcccttgca tatgaaatcc ttcagtaaag attttcccga aataagttaa acttccaacg
    35761 atgatgctcg aaccggcact caacacttga aatcctagga gtgtctttaa cgtgccagag
    35821 atgacttgtc ctgctgattt cttctgcagt agtagaccca acatagcaat caatgcaatg
    35881 gtgatcgatg cctgagtcaa aatattttcg atgataaaat tgataacgcc catgttttta
    35941 ccctcttttc tttttgtatt tagataactc ccttatcttg cagaactggg gtgatttttt
    36001 cttcaatttc attttttgaa acaatatttt tcaaatagat catcgccgtt ttaggatcaa
    36061 ctgcgaactt ttcgaactgc gaacgaaaat tttctgctgt gatgatcaca tctggtttca
    36121 tggaaactgc ggaagaaata tcacaatggt ccagtttggc ttctactcct aatttgttca
    36181 aaacatcctc agcagacatc tgtgctgcaa aactacttcc taaacctgca ccgcatacga
    36241 ataaaatgtt caatttgttc atctttgttc tcccccgtat catttattat ttctcaacta
    36301 ctgaaaaaag cagttgtttg aaatcttcga tatttgtgca ttcaatcaat cgatccaact
    36361 tctcttcgtt gttgatcaat tcaattagtt ctttcatgat gttcagatgc gagtaggagt
    36421 ctactgctgc caaacaaaaa ataatcttta ctggatccat ttcaggatta ccgaaatcga
    36481 ttggttgctc aatcgtagct acgctgactc ctaatttatt gaccccatct tctggtcggg
    36541 catgggctag tgccatgtgt ttgccaatca cgatatacgg tccgtaatca ttcactgcac
    36601 gaatcatcgc ttcgacatag cgctcttcga caatgttttc tttaaccaat ggtctagcag
    36661 ctagttcaat cgattcctcc caagtagtgg ctttttcttt gatcatgata ttgctgtccg
    36721 tcaaaatatc ttttaacata ggctggatct cccttttgtt gatttctaaa ttgtttgttt
    36781 cgaataattt ttctaacttg ccatagatga ttcgatctac tcggccacca ctttctttca
    36841 tgacatctat tatttgagtg aataactccg tcgattcatg actgttaggc tctaaccgct
    36901 gtagttcttc atttcttttc aaaaagtctt ctataaccaa gatattcgtc tcagttaaaa
    36961 tcggatcgac aactaaaagc ggcttatttc gataattcaa ttgaaaggtg ctgaaaacca
    37021 gattgacatc caatttatct actaattcga tttcttttga acttaaaact gcagtaatct
    37081 cgatctgagg aaacttttct ttcagattct ctgctaacag atttccagta gccatcccat
    37141 ggttacagac aacgactgat ttataaacat aattcaagtc tcgcttgatt acactggcga
    37201 tcgtcgaaaa gtggatgaca agaaaagcta tctcgtcctc cagtatcttg ccaccaatta
    37261 cttcttcgat cgtaggaaca aaatgagtga ctgcgcggta gattgggaaa taatttgttc
    37321 ggatgttttc tttcaatgga ttcatgactt ggatatgatt cttgattctt acaatcagtg
    37381 cagccatgtg cttatagaga ttttcgaata aagcttcttc ctttagatgg aaaggtacgt
    37441 gtgtctcgtt ctctacaaat tggatcaatt ggatcgttag taattgagct tgtacccact
    37501 cgattgaatt ggagatatct ctagcattga acgtctcaat agtgaaacga agataatttc
    37561 tttctacttg cgggacattg tccaattgaa attcctcgat catgtggtca ataaatgcag
    37621 aaaagctact gtcttttatt tctgtatttt tccaattaat ggcagagata aattcatgtt
    37681 tcctgattcg ctggatccag atcaatgtaa aaagcaggat ttgtttttta taaatatcat
    37741 cttcttgttt caacaactta ttggaataga tctcctgtat ttttttgatt tccaccaaag
    37801 gaaaataatg gagaaagatt ttttgagccg gtgttaattg tgcatcttga ttcataaaga
    37861 agtcggtcat tcccagattc tgattgataa aatcatagat catcgtacgg atagatcgtt
    37921 ctgaaccttt ataaaccagt ccttgctttc cataactgac gatctctatc ccataactga
    37981 ccagtgttgc tcgtaaccgt ctcatatctt catctaatgt acttttagag atttgaaatt
    38041 cttcttcttt tttgtttaga tggatcggga ttcggctgta agcaacggct aaaactagat
    38101 caaaaatacg ttcgcgccga ttcaaaaagc cgtctttcac atcttttatt tcagtttcta
    38161 atcgagcttg cttttccttt tccagcttca acaaaaaacc tttgttgcga attgtacgga
    38221 tctccggaag ctttttactg ctcaaccaga tattcgcttc aagaacttcc tgacggatcg
    38281 tccgctgact gacattgaac tcacttgcta gatgttttgc ttttactgga tattgggctg
    38341 tcatgattct gtgaagtatt tcaattgttc ttgttttcat agaaatgatc tccttctgat
    38401 ttcaagtata tggttccgct tacataataa aaagtagata tttctgccac ttgaagtgga
    38461 aagaaagtaa gcaaagcaaa caaaaaataa gccatatgct ttttcatctc ctcaacgaaa
    38521 aagacatacg cctattatta caaaaatttt gcccatctat acaaaaaaga ggttgtgaaa
    38581 aagctgtcct gcatcaagta ataagaacaa ctaaactaaa atagtgcttc ctatttttcg
    38641 tttggttgtt cttattatcg cagatgcaag cttttaaaca ccatttagtg gagaggttgt
    38701 gacagagatg ttcagccttg agcgataaga agcgattttg aaaaatcgct tcccatattt
    38761 tacaaaatcg tgccttattg ccgataggct atctctggca caccgtttat tcagaaaaag
    38821 gagctgcgac aaggcttttg tcacaactcc gttcataaat atttcctgtc aatccagcat
    38881 aatcggctga ataaaatcgg cttgccatct tttttctttc tcagaaaaat caaaatacca
    38941 tatctgagaa aaatactgtc gttgtgtctt acttcctgag atcaatcgcc catcttttcg
    39001 atcgactgaa taatcacagc atctgaaatc aattcggatg gcaaaactat tttcgtggat
    39061 ctgtcgataa tttcctactt cctgaatagt tattttttta gtatgatttc ttacaccgtc
    39121 tgctttgttt ttttgcagaa ctttctgatg ttcggcaaac agcttgtctg tataacagct
    39181 tctggctttt tcaggagttt cttcttccca agcggattgg atcttcatga atatcttttg
    39241 gatttccaga aactgtgctt tcttttcttt agccgttcct gacatgcggg acaatatctc
    39301 cgctttcagc cttttctttt gtcttttatt cttgacgata gaaaaagcag aaacccctcc
    39361 tactgacaaa acagctaatg caagaaatcc cgtttgctca taactagaag gacctgtacc
    39421 tggaccataa tacccataag aatctctgcc gtaagaacga ctgccaaaat aactgccccc
    39481 atatgaacga ccaccaaatg aacctctgcc cgaacttcga ccgctagatg tacctccacc
    39541 atgaccaccc gcgacagcga atccttgggt cggcagagca aacaaacata ggcccactaa
    39601 caaaatgatt gctaaataat tgattttttt cattgtcttc ctcgttatct tttattacaa
    39661 aaaactattt ttatgatagc cttgctaaaa ggaagagtca ataaccagat gcataaactg
    39721 tttttttagc aattttgtct tatttagtca ttgagtaaca tcggacaaat gtatgtgtcg
    39781 gcagtccata attcctctat cttcagcatg aacaagcttg cagacaagag atctgcgctt
    39841 cctccaggag agatttggtt ttcctgacaa aagtgcaaca gtgctgtaaa tggacgattt
    39901 ggtaaagcac tttgactagc agcatgagca agtttttgca tttccactaa cgttttctga
    39961 tcactgcgat gcaatacgca tgtgtcatct agcgaactca tcaaaactaa caacatatgc
    40021 atttgtttct gtacatatga atcattatct agctccttag ctgcttgaat tgcaagcctg
    40081 atatgcggat accctaatat cgcttcttca tatgcaccat ttacgccata tttttgcttc
    40141 accctatgac catgagtggt ttttttatga cgatattttg tatcaggaaa agcagcaagc
    40201 ttgctgacat catcaagtat tttcgataaa gaaaaaggct gttccatact gattttttgt
    40261 gcaatgacac tgatcaatag ccccattgcc caaatcgctc ctttatgggt attgatgcca
    40321 tttgtagcaa tcagcattgc cttttccgct tttcgcccaa tctcagcaat tctttctctt
    40381 aactcctgat caatagcatg atgccatgct atttgagcca tttcttcaaa aaaaggagtt
    40441 agcgtcttag cagacttaag aaataaagca tagtccatat cggaatgtgc acccgcatcc
    40501 agtgcatcca ctaatccagg ttttggactt aatgttactt ctgcgatcaa tgcttcctct
    40561 accaacgcag cgagttgctg agtcactgct ttttttcgtt cgtcatttat catgacactc
    40621 actccttctt cctactatta cttgctgaaa ccttttttga tagctaccca aatgatatga
    40681 agtaaccagc ttaaagcaaa tgcacaactt gccgtcatta gataagctac aagaatcatg
    40741 actcctgaag gtaactgcag ccaactatct ttaaacaata ataacagtac ttggaaaaca
    40801 aatacattgg ctaaatacgt acgataagca taaacagaca accatttgaa caatggcaat
    40861 tttggcgaat cgtttacaat cattttggaa gcgcctatga agacagcaaa gatgatgact
    40921 aaactgtata aactttggat cgtattcaag taaggtgcat tcgcaaagct caagtctcct
    40981 ggatgtgcga gcaatgaacg gacagaaaag aacgcgataa ctaaggcaac aggtaagaaa
    41041 agataacgta ctctgtccaa atattgatag actttttcgt gataaacaaa tgcggctacc
    41101 ccataaatca tgaaactagc aacaaaccga tctaataagt accagctgtc atgataaggc
    41161 ccagtcaata cttgtgtttg atagaacaga taccatgcga catataaaat cgttgaacca
    41221 atcaatactg gccatacata ttttttatta gcaaatactt tgtaaccgag ccaaacaaaa
    41281 aacggcatga acaattggat ctgcagcatc ataacggtat accataaatg aggcgctcca
    41341 tcacctgtga catatttcag taaaaagctt gcagtatccg tatacggagt ttgttgttgg
    41401 actgctggaa atagccaaag ataagccgtc gtccatagaa gatacggaac gactagttca
    41461 aaaaactttt ctttcaaaaa ttcccaataa gacaaatgct gacttgtttt taccatatta
    41521 taaacaattg caaaaataaa cattggtgct gtgtatttaa cgatgacgta aaaggtacca
    41581 agaaaagctg tatttgttgc gctgtggctg tttgccaaag caaagctcaa tatcgtttgc
    41641 atcataacag ccgttacagc tgatactttc tggaagtcac ttacgttgat tttgattttt
    41701 ttgttttcaa acatctcttt ctctctcttt ttctttatta ccaaagttct ttggttaatt
    41761 taggtccttc gactgttttc aatagaattt ttttctctgg ctctctcaaa tactctttta
    41821 gtgaaaaacc gccttgccga gtcactactt gggtatcgaa ttgctcaaaa aaagcaggat
    41881 gcgattgaat tacctgaatt ggcaattcaa tcggtgaatt tgcgtacagc agcaaatcaa
    41941 aatcactggt ttcttttact gccggaatcc cagtcgataa ttcaaatcct aagctgccgc
    42001 cgattcccca tttacatcct gataatatgt ttctagcagc atgaaattgc tgataaacag
    42061 gataatccat gattttctct tgtctatacg attcttgttc gatgatgtcc cacggatgaa
    42121 tgacttgttt gacggcatgt tttgagattt ctgttgacca tctctgattg cgggcaggtc
    42181 cacgtaaacc aatcggtagt atttctgcgt gatccgtcga cgcacgacga actgttccga
    42241 acatcttttc agttagaacg acccattcag gcaaggtgaa cccttctatt tcatgtttat
    42301 caaaaaggac aatatcatgt gcttgaatca ttttttatgc atcccattct tcgtccattt
    42361 tggcacggac tttatttgtt tcgacacgtc cgaatgtttt ggctgtttcg tttgtgtatc
    42421 gatttgtcag catcgtgtca tttgtattgc ggacatcttg aatggcttca ttgattgctt
    42481 cgatgacttt gctgacattt tgttctgaag cagcttggtc ggtgatatct tctaggaaat
    42541 gatagatcgc tcctagtttt gtataattat tgatatcgta agcgatagct ggaacttttt
    42601 cagcagctgc ttcgatttca gcaaccgaac gttttgtcac acgtgcagca ctttctttag
    42661 acatcgcttg gacggtaatt tctttattgt ttaaagcaat caagcggctt gattgtaatc
    42721 catgtgctaa aaatgcacct gaaatagcat ttcctgcaat caatccaata actggatgtc
    42781 cagcttgacg gagttttgca taagcagcag cactattagc caaagccaca tggataccga
    42841 tcaattcttc gttatagccg tatgcttggc ttggtacatc gatcacaacg atgattggcc
    42901 gtttcacttt tttgtcttta tcttcttcgt aaacgtgatc caaaatttgt cccatgcgga
    42961 aaccttcaac taaaccaact tcaccgtttc gtacacggta catcgggttt ttaggatcag
    43021 gtacgattga tgtcacgatg gcttcttcta tgaatttact tgatttacca taatacacag
    43081 tactaataga agaagttgga tttttcatgc cagttagtgc cgcaaaccaa tcgtaaccaa
    43141 cacttgctgc agctggttca tttccttctg ctacttctgg taagtcaatt gattttgctt
    43201 gatggttagc aattgcttca ttgtaatcgt caatggccat tggttttgaa agatctaaag
    43261 aatcaagtaa tgataaataa aatgctgagc tttcactgcg atgcgtgtct tttcgttcgt
    43321 ccattgctgc gatgacagca gctttgattg cttctacact atcagtcact aattcatcaa
    43381 tgatttttga ttctacccgt tgacgagatc ctaatgtatt ccaaatcaag tctttgtcac
    43441 tagaatcaaa ttctcgaacg cctgcttctt gttcaataac ttctggtcca ttcaaaccga
    43501 ctctcgcttt ttttgttgcg attaaataac tcattaatgc tgaagtaatc gacataccgc
    43561 caaatgatcc tacacgtcct ggaatcaaac cgatgactgg tacatattgt tttagagcaa
    43621 tgattacatt tccgatttct gaaatagata acagtccgta gtttgcttct tgcaaacgaa
    43681 caccacctgt atctagtaca atgactggaa agatctcatt tcctttttta ttttcttcta
    43741 acacatgttc aagtgcagca acgatttttg caccggaaac ttcaccgata ccgccacctt
    43801 ggaattttcc ttccatagcg attactactg cttgtttgcc attgatcgtg ccacggctga
    43861 caacgatccc gtcatcactt tcagggacga ttccttgtgc tggtaaactt ggcgcgatga
    43921 tttgatcgaa tggatcaatc aattcacgtc cattgtcaag tagagcgttc actcgttctc
    43981 tggcgtttaa ttctacaaaa ctatttttca tctgaaagtt cctccattgc ttgcgtcaat
    44041 cgtaggtaca caactcctgg tgtagcaccg aagtcattga tcacgatatc tgctgaaatt
    44101 ggataacgat caaaaaatct cgttaataca ttgttccata cttcgccgaa gccatcgctt
    44161 cctgtacaaa tttttacagt agattctgtt ttttctgttg gaaacatcaa gatttccaaa
    44221 tctcctgaac cgaccactcc tacatggatt ttcttattga tcggctgttt cgttggatat
    44281 ttataagcta attgttccat ggatctctcc cctttttgta aaacagagca tacacgttct
    44341 gcttattcgt ctttcttctt ccatctgggt aaatggcgac aaaaggtttt tctcgccaat
    44401 tttatgacca agttctgaat ttcattggtg gttcatacag gccatctgac cattcgatca
    44461 aatcatcgat ggtttgtgca gctaataatg aacgtttcgc ttcactacgt ttgatgccta
    44521 gatcttctgg taatttcacg atgccggctg cacgcaagct atctagtgat tctttcgtgc
    44581 tagtcattcc aagaggtgta acaccgccaa ttgctgcaat tgctgcttgt cgttcttctt
    44641 ttgtttttgc tttgtacaaa taagcaattc cttcttctgt cacgatatgt gtagtatctt
    44701 cgctataaat catcactggt gcattggcta agcctgcttg tttttgaaca gctagtgcat
    44761 ctaattcttc gacaaagact ggttttttat ttgaaccata tgtttcaacc atttgaacaa
    44821 ctaatttttg gcctttccct aatggatcat cattgtcgcg aagtgattgc catgctggtg
    44881 tagaatgacg acgaccgcca ggattatgtc ccatgttagg cgcaccgcca aaaccagata
    44941 aacgtccttt tgttacggta gaagagtttc cttcgtaatc taattgcaag gttgaaccga
    45001 taaacatatc gatggcatat tgtcctgcag cttgtgataa tgttcggtta ctgcgcatcg
    45061 tgccgtcttt accgacaaaa aagacatctg ggcgagcagc aatatatttt tccataccaa
    45121 cttcgccacc aaaactatgg atgctttcaa cccaacctga ttcgatggct ggaatcatcg
    45181 ttggatgtgg gttcaatacc cagttcttcg cgattttccc ttttaaccct agtgattcac
    45241 cataagttgg cagtaacaat tcgatagctg ctgtattgaa tccaataccg tgattcaaag
    45301 attgtacgcc gtgttctgcg tagattcctt tgattgccat cattgccatt agaatttgca
    45361 attctgtgat gttttgagga tctcgtgtga ataaagcttc taattgataa ggtttatctg
    45421 ctttcacgac aacgtctacc cagtcaccag ggatatctac acgtggtaaa gaatcgacaa
    45481 cttcgttaac ttgaacgatc acgataccat ctttgaaagc tgcagcttcg atgattgttg
    45541 gtgtttcttc cgtattgaaa cctgtgtaca agttgccgtc tttatctgct ttatctgcag
    45601 ctactaaaac aacatttgga atcaaatcga tgaataagcg tccataaagt tccaaataag
    45661 tatggatatc acctaatttc attgtgccgt cttcaatcat ttgggcgaca cgcaagcttt
    45721 gtgcaccagc ataagagaaa tcgatcttgc ttgcgattcc tttttcaaaa atattcaaat
    45781 gttctggtcg tgagatacta gacatgatca aatgcagatc attcactttt tctgcatcta
    45841 ctttttcaag actttctgaa agaaaacttg cttgtttttg attgtcgcct tctaatacaa
    45901 ctttgtcgcc gggagcaatc agtttttcca ttacttctac gattttttca gtttctacat
    45961 acttgccatt gagcaagttg ctgatttttt ccaatcgctg cgcttttttt tcgcgtttag
    46021 aagcccagtt gcggtttggt ttttccataa ttagtcatct ccatttttga tatagaaacg
    46081 tggcgtcatc aataccatgt tggtctagat tgatcgtacg gatcccttta tctacaccaa
    46141 attttgtatg aatcagcttt gtcaaagtat tgccgggggg aaattcaatc gtcagatcca
    46201 ttcctaattc ttttgccaag tccatcattt ggttccactg cacagggaaa gctaggtttt
    46261 ccaacaaatc tttacgaatc tcttctgcgt cctgagtggc tcttccatcc gtatttttta
    46321 tatacaaaca tctagcatca gatagatgga cagactgcat atacggcttg aatttcttga
    46381 ccgtatcatt catcaagaga cagtgagatg gcacagggac tttcagcagc ttcgctgttt
    46441 gcgcttggtg ccgtttggct tctgccaacg taacggataa accttcgata ctcccagata
    46501 acgtatgttg catcggacaa ttttcatttg acagataaac tggatggtca ggatcaaatg
    46561 tttttgctac aatttcctca gcttcgcttc tcgtcacacc tactactacg cccattgcat
    46621 aaccgcttgg ataagcttct ttcattaaga ctgcgcggtg atagactagt tccgctgcat
    46681 tctcaaatct caaagatcga caagcaacag ctgcacaaaa agcaccaatc gaatgtcctg
    46741 ctgcaatatc aggctgaata ccgttttttt ccatttcatc taaataaaat actgcttttg
    46801 tcagtaatgc tagctggata aaaaccgtat cttgatagtt ttcttcttta tcaactaacc
    46861 gataccccgt cacattttct aaacgttcca tgtacatttc agggatatcc gctaacatcc
    46921 ctaacttctg actgccttgt ccaggaaata agaaacctgt actcatgagc ctcgcctcct
    46981 cagcacttac tttttccact gctatcttag tcaatttctg ctataataaa aaatgccaaa
    47041 aaaagaaaaa accataacaa aaaggtatgg atgggatgga taattatgaa attgcttcat
    47101 ctgcagtatt ttaaaaaagt attcgaaaca aaaaatgtta cccaagcagc caaagaatta
    47161 tttatttctc aacctgcctt gagccgtgcg atcaaacatt tggaaaacga attaggtgtc
    47221 cctttgtttt accatagcgg cagaaacatt gagacgaccg tttatgcaga agaattttat
    47281 ccatatgcag tcaagacatt agacacatta gaagaaggaa tcaaattatt gtcttcggtc
    47341 aatgagaaga tcgttacttc cgtcatattg tatttagagg tagcctctgt ttctattccg
    47401 aacttggtcc gaatttttat ggaaaagcat cctgatatcc aattaacgat catgcaacat
    47461 catttaccag atgatattac cgatcctgta ctgtacatca cttcggagat gaagcctggc
    47521 atgaccaata ttcctatcat gaaagaacct gtttatgtcg ccattcctaa gaaacatcct
    47581 cttgctaaaa aagaacatct gcaattagaa gatatccaac gcacccccat cttgatgctg
    47641 tcaaagagca acgccttccg tcatacactg gatgcagcac ttgaagcgaa aagtatcgaa
    47701 ttgacgatca gttcgacgac agatgatcct gcgacattac gttctattgt caagcaagga
    47761 ttagctgtta gctttttccc aaaagtttct tggtcttacg ataaaaatga tcctttcgtc
    47821 ttgcgggaaa tcaaagattt gcccttgaca cgaacaattt atttatcttc tagcttcaca
    47881 gaagatcatc ctttgatcaa aatgattgca aaaacgatgc gggaatttta tttaggaaaa
    47941 taaaaaaaaa agagctggga caaaattctt gtcgcagctc ttttttcgaa caaacggtgt
    48001 tccagaagta atttcttaga aaataagccg aaatttccca aaaatttgag aagcaatttt
    48061 cgtaaattcc ttcttatttc ttgaagctaa acatttctgt cacaacctct tctctattgt
    48121 cctagacatt cattgcgttg atttaaaact tccatcaatc aaatctgcta gttcatctag
    48181 cttttctatt ttacgtagat caatagagat ccaatgttct ttattcatgt gataggctgg
    48241 aaaatacccc tcttttcctc gcaaaattcc gccaagttca ggatcgacct tcaaatcaag
    48301 aatattgatg atcctatggt cacttgcatc atcatagatt ttttcttctg gaacagacat
    48361 caggacccca aaccattttt tgcttttttg atgtctgaat acgcaataat caggaaattt
    48421 tttaaaaata tattctggag acaaattgta tgtttcattg atgtgatcga ttagttcttt
    48481 tttcgttagc atctgcttcc atctctttct tattgattcg ctttattcaa agataccacg
    48541 taagaataga aaaatgaata caagtagttg ctaatcaaat acttcgatat ttttcttttt
    48601 tatcaactct taaatgttca atccgcctgt gttggtcttg ctaccatcta ctattaaaat
    48661 gtttattatt gtttgcccac ctattttttg attttagtgg tatcattttt caagttcatg
    48721 atgaaattct tatcatcagt aaatgctcca gaaaaataaa caatgattga aaaatcagtt
    48781 gaaacttgac caccgtttat tttctccgta ttcttagaat agaagggagt ctgattgatg
    48841 tattcactaa tgaaaaaaat cattaccgaa aaagatattc gacgtcatgt ttctttagta
    48901 gaacaattgc tgaatcatac aaagataacc gtaaatgaat tagctgaaat catagggaca
    48961 accgaacgaa cgattttttc tgaccttcaa tctattcgct ctcagctgcc cgaaggctgg
    49021 gacatcatca gcgatcaagc aggaatcagt ttgcaaaacc agcaaaattt attaacaaat
    49081 gacctttggg agattttttt caaacaatca gtcagtgtcg aactgctgaa aaatctgctt
    49141 tttacaaaaa aagttgctgt ccctgatttt ctagccgacc atgggctttc ttatgggaca
    49201 ttgaaaagac atgtgactaa aatcaatcag cgtttagcaa gttacgactt gcagatcgat
    49261 ttgacgaaat atacagcttg tattcttgga aaagagcgtg cgattcgtac tttttatcat
    49321 cgattgctga ttcctttcac tcataacaac tattttttcg aggattattc gatccatgaa
    49381 tcccattatt ttcaattttt aagaaacctc agtcaaactg aactagcggt tgaaacagaa
    49441 gagattttcg gaacatgttg gttctttatc aatacgatcc gtataaaagc gaattgccga
    49501 ttagattctt ctatccatac caacagcaca ctctcctccc tgtatgactc tgcattgaaa
    49561 aaattgtatt taacggaagg tatttatctt aaagacactg agctttcttt tgcttctttc
    49621 tgctttctgg aaagttggaa ttacaacaat aactatggac aagaaaccgc tcgctgcctg
    49681 catcattctc catttttaga ggtcctcgaa acgtttgtag aggaactagc ttcagagctg
    49741 tctcttgatc aactaaaaaa aacatctctg actgataact tggctctcct catattaaaa
    49801 tatcatgaat cgccgatatt gattgaagca ttggaccgtc aataccatcg ttttttagaa
    49861 acatatgatc agcaatatgc acacttgtat caacagaaag agaatttact gaacgatcta
    49921 aaaaaagaaa tagaaatcaa tgaaccaaat tactttctcc aactcttgtc tctactgatc
    49981 caacaaacga ttttttctat caaaccgaat ttgttcaatg tctattttat tttccaagga
    50041 gaaccttcat ggaaggcgtt cttgcagcag gaattaaaag attacttagg aaaacgtgtc
    50101 tgcttcttac ctatcgaact aaccgatctt tccactattt cttttgaaaa aacagatatc
    50161 ttgatttcca atttccctct agattctcta gatatcccta ttgtatacat ttcttctatt
    50221 ccaacgaaaa atgagctcaa tcgtttgact gaactcactt tcaaaacttt tttatagtaa
    50281 cggctagcga ctgtattctc tagctgtttt ttcttttttg cgaaacagtt tgttcatgat
    50341 ccctttttct atttctacaa ctaagaatag aagaatcaca tttgctccaa tcaataactg
    50401 ttgtgtcatc gttaaactta ctgtaccgat cagctgctgg ccgactggta gaaaaataac
    50461 catcccttgc aataaagcaa ggatacctaa tgaaagaaaa agcgctttgt tttgcaaaag
    50521 accttggttc aatgacggct tggacaactc tctgcaattg atcatgtaaa cagcttgagc
    50581 taagacgata ttttgcagaa gaatggtttg ctgtaagctt tgcccttcaa actgcatagc
    50641 caataaatag gcaggaacca tgatcagtag ggagacatag atgatccgaa acaaatgata
    50701 accagatagg attccttgct ttggatctct tggtgggcgc ttcatgattt ctggatctgg
    50761 cgactcgaac cctagtgcat aagataaagt gattgtcgtt accatattga cccataaaat
    50821 ctgtactggg gacaaaggta gcgggcgatt cagcataagt gcccaaatca agatcaatcc
    50881 ttgagctaat gcagttggca agaagaaatt gatggttttt tgcaaattat ccaaaatccg
    50941 ccggccctct tttacggctt ttgcaatcgt atggaaatta tcatctccta aaaccatatc
    51001 agctgcctgt ttgcttactt cactaccttt gattcccata gcaattccta catcggatct
    51061 tttcaaagca ggtgcatcat ttacgccgtc tccggtcatt ccgacgattt ctccattttt
    51121 ctgcaaagct ttaacaattc gcagtttatg ttctggtgtc gttcgagcaa agacatcgac
    51181 tattggcact tgctgaatca actcttcatc agacataaga tccaaatcga tcccttctaa
    51241 aactttggca gtatgtttta agccaatttg ttccgcaatc gcttttgctg tgtctttgtg
    51301 atcccctgta atcattttca ctgagatccc tgcttgttgg cattccttta cagctttgac
    51361 tgcactttct tttggcggat cgatcaatcc ggcgatccct gcaaaagtta attgggttaa
    51421 agtctcatgc gtgagttcct gtttcgaatc tactttttta taagcaaatc ctaaaacacg
    51481 ctgacctttt ctcgcaaatt ctgcagctgt ctgactccat gcttcttgtt ctgcagaaga
    51541 aagagttgat ttagcaaata atacttctgg tgcacctttg acgtaaatca ccgctccttt
    51601 ttcctccgca tgcatcgttg ccatatattt gtattcagaa ctgaacggaa tctttgcttc
    51661 tatttttttc aaaggtagat tggctgtttc tgtgtgtcga atcagcgcaa cttctgtcgg
    51721 attgccactt aaattttctg ttttctgttc ttcttttgtt tttaattcct gacagttttt
    51781 cataatggac aacacgcagg cttcttcttt tgcagctaca tccacaactg tcatttcatt
    51841 ttttgtcaat gttcctgtct tatctgaaca gatcactgtc atagaaccta atgtttctac
    51901 cgaaggaagt cctttgatga tcgccttttc ttttgccatt tcatgtactc caacggatag
    51961 aatcatggtc aaaacagctg gcaatccttc gggtaccatt gacaccacca aagcaatcgt
    52021 agccgaaaga agaatatgcc aatccatacc atatcgaaat gtcgtaaaaa taactaagaa
    52081 taggctcaaa caaagaatgc cttgaaaaat ttgtttgttt aatcggttga tttttttaat
    52141 cagaggcgtc gtttgttgtt cgaccgattg caatgcttga ttgattttac cgatttctgt
    52201 cgtgtttcct gtttctacaa cgacaccgac tgcagaacca gattgtacaa gcgttcctga
    52261 aaaacccata tttttctggt cgccgatcga ttcttcttct gtcaaaacgg catgactttt
    52321 ttcagatgct tctgattctc ccgtcaaaat cgattcttcc actaataaat catgtgcttc
    52381 gattaatcgg atatctgctg gaacgacatc tccggcacgt aagacaatga catctccttt
    52441 taccagttct ttcgcaggga ttttttcttg catcccgttt gatagtacta tcgcttcttg
    52501 tcccatcagc tgcttcaaac cattcaatga ttcttccgct tttctttctt gccagtaact
    52561 aacgagtcca ttgacgatca ctacgaataa aataatactt ccttcaatat attcactaga
    52621 agcaaatttc aaaaaagagg caatgatcaa cacgatcatc agcagatcag taaaatgctt
    52681 tgctattttt ttccatcgtt ttgtctgctg ccttgctttt atttcattat atccttgatc
    52741 agtcaggcgt ttctgtcgtt cttcttgcga caagccttct gttgatgttt gatagttttt
    52801 caatacatct tctaccgtca atctgtacca gttcatccta tcccctcctg tttaattgat
    52861 actgttatta tacgcaggga agttttttca ggcgtatcga ttatttcagg ggggtctgaa
    52921 ataattcgtt ttgcaaaatg tatctgggcc taactgatat ttctattgct tattctttta
    52981 tatacaaaat ttaagaatac aaaccagata accaataaaa aaggaataaa gcgtgtcgtg
    53041 ctttcgaata acaagctgaa agcaattgaa gtaaaaaaca ccaacaaagc aagatcttta
    53101 tatctttgtg tagtgttccg tttcttttct ttaataaatt gaacatgtgc acacaagatc
    53161 gaagaccaca caaatagaaa acaactcgtt gtcatgcctg ccaaaagctg aaaaaacaat
    53221 cgactatcag ctacaaaaaa atgtagacaa agaccggcaa aaaataacat tcctgtaatt
    53281 aaaataccgt gtaaaggtac gcctttctta gaaagcgcac aaaaccaatg gggcaaactt
    53341 ttttcttttg ctgtttgata taaaatcctg ctagtactgt agactgcact atttgctgag
    53401 gacaaagaag caaccaaaat cattagattg acaattgctg ctccgccttg gcaatggatc
    53461 acttgcagca tagtcactaa aggactttct tttaaatcta aacaatgcca tggaacaaca
    53521 aataaaatcg acaaaatcgt tcctatatag aaaaagagaa tacgccaagg cagacagttg
    53581 attgcttttt tcaaattctt ttgcggatca cttgtctcgc caacggttaa gccgatcatt
    53641 tcaattccag caaaactgaa taaaaccata ggaaatgaga ctaccattcc agcaaagcca
    53701 aacggtagta attcatcgat ctgtccaaaa ttttctttga ttccgataga ctgggtatga
    53761 aaatctgaga cactcaatcc tatacccaat aagataaaaa ggaaaatccc caagatcttg
    53821 atgattgaga aaaaagattc caattcacca aaccacttga ctgcaacaag gttgactgcc
    53881 attaagatca ttagtgcgct acctccgctt atcaaagctg gtacatgtac aaaccagaaa
    53941 tggatataca atcctattgc tgttaattcc gcaagtccag ctccaagcca gcaaagccaa
    54001 taagtccaat tgacaaaaaa tgcccacttt ttgcctaaat aatagtcaac gaaatcactg
    54061 atagagttaa atgtactatt tgctaaaaat aaatcaccca tggcccgcat caaaccataa
    54121 atagccaaac cgcatatcaa ataaacgaga ataacagctg gccctgctga tgcaattgcc
    54181 tttgctgaac ctaaaaataa tcctgttcca attgcgccac ctaatgcgat taactggata
    54241 tttcgattag ttagagtccg tttcattgcc ggtttttcca tcaagttcac ctttttcttt
    54301 ttcaagcagc atggcgactt cctgttccca agaaggtttc tttatttttt caatacagag
    54361 tggtactaca aacaaaatga cactgatggc tgtgactgca attagattga tccatgttcc
    54421 agctttcatc gtcagtccga cagaaaatcc gattgccgca aataaaacaa taacgacagt
    54481 ccaaactcca agattgctct ttttctcttt ttttccaatt ctaaatggtc gattcaactt
    54541 tgcatgtgta taacgcaatc tcaaaactgc gatccccatg atgacataga cgatacagta
    54601 gataacagta gttgaattta cgagcatcaa aaatgcttga ttgacgccag gaatcagcaa
    54661 ataaaaaagt gcaaagattg agataatgac agactgagtc aaaataacgg atttggatac
    54721 gtcaaattga ttcgtcttcc aaaaattgaa ttttggtgga tacgcacctt ttctagcact
    54781 ttctgtcact gtctttgctg gtcctgaggc ccaagcagat aattggactg ctacaccaat
    54841 gaagacaagt aaactaaaca gattcacaat aagatgtggc aaaccaagaa tttggcaata
    54901 aatcgaaata gattgcgcga tattattcaa ttccatttgt ccttttggta cgacatttgc
    54961 tacaactaaa gcattcaaaa tattgacgaa aaatataaaa attaacgcgg caaatactcc
    55021 gcgaatatac gttttaactg gattttccaa tcgagtgata tacacagagg acatttcgat
    55081 accagtaaaa ataaacatga tcggcgcaaa ataaacaaat gaggatgcag tcgtagtatc
    55141 tggtattaat ttgtcccatg aaaaactgcc taatgttccg gttggtacga tcccaacttt
    55201 gatccacgca gcaaacccta ataagagcat catcgtcaaa ggcacgtaca atcctaacca
    55261 aacaccgact tttccgccga tttttgccat atcaaatttc aaattcaaaa aagtgatgat
    55321 ccaataaacg actaaaatga caactaatgt aaatttgctg ttcaaaccaa gcggcacatt
    55381 atcgataata ttaccaaaca acggagcgag tgctgaagcg accatcacca tcccaggaaa
    55441 catttggacc cataacagcc atgagacaac gaacccccat ttttttccta gagcattcga
    55501 tacccaaagt tctggaccac ctttttgggg aaacattcca gcaaattcac cagagatcaa
    55561 tgagattgga aaagcgtaca ataatactgc aaccagcatg taaaaaatca tcgtccagct
    55621 cgttgctgct acatctggaa tatttcgtac acttgctaca agggcgcagg tcattccgat
    55681 aaaggtcatg gtcgtgattt gctttgatga accagtatct ttcatcttta ttccttcttt
    55741 caatagcgac atatgttttt gttttctttt atttttgttc aagaacagaa atgacaaggt
    55801 ttcatcgatt cagtacaaaa cccagtatca ccgaaacatc cattgaacga tcttagtgaa
    55861 ctgggtttga tacatgaaac gaacgatcca acttatagaa cgttttataa aaaagaatat
    55921 cttggcgagg aatatatgaa aaacaggggg aaatacaatt gttttgatga agcaaataat
    55981 tgtctgttct ccatatgtct cttgttattc tttcacacaa aaatcagttc tattggatga
    56041 tttcgtttag tttcttttcc attgctttgg cgattttttt tgtataaaaa ttgaaaattc
    56101 gatcatcatt caaataagga gtcatgatag ccgcacgtag cagagtgatt ttctgttctt
    56161 ttttccattc ttctttcgtt agacccattc tttcaacaaa acgaatcgga gaatcaccgt
    56221 aatcttcttg tgtaaatgta gtatgagaag taataaaccg ttcaccataa acatcgccat
    56281 ccatataaga agaccgatcg aacatttttt catttaattc attgatagcg ttcaaatctg
    56341 tacagccttg ttctttgaat acccaattga ccatattaaa atcaggatga ttcaatggat
    56401 agacttcgat tgtttttcct ttaacagtaa aagtcagatg atcgagaaat tctctgaatc
    56461 tttgagctgc ctcgattgaa gccccaatca attgaccata tccggtcaca ttcaatggca
    56521 atacacgatg tgctgtccag actgcggcgg cggttgctcc agcttttgat ccttccaaaa
    56581 tataagctcc taacatatct ggagccttta ctgatttttc aaacacatat ggcgcgaaat
    56641 aagaaatgat atttctcata tttttatgtt tgattacgat tcctccagca gcataaggga
    56701 catagcccat cttatgagga tctatcgtga cagaatccgc ttctgaaata gctctgaacc
    56761 cttcatatac ctctttgtca atcgttacgc agtggtggaa aacatgatgt tcttcaaaga
    56821 attcagctaa ggaagcatac ggcacaaatt ctcctgcttc gtttagaaac agtgaacgcg
    56881 catagccgcc atatgcggca tcaacatgta aatagaaata gatcccttca tcttttaacc
    56941 tttctcttaa ttggacgatt ttatctacac tgtctacttg accttcttct gtcgttccta
    57001 cgacagcaac cacacctaga attgggattt tttgtccagc taattcacga attgtttttt
    57061 ccaaagcatt aatatccatt cgataatcct cttgaactgg gatagcaacc atctgatcta
    57121 agccgactcc gcaaatatct aacgccttca tccaagaata gtgttttgtt tgagggacca
    57181 gccatttccc taatctttgg atattttttc cgctacggga agaagctgct ttgacctcat
    57241 ccatttcttc gtccgtaaag ctttcggtca tttccaaaat ttcttcaaca gataaattca
    57301 aaagttccca ctcagacatt tttttcactt tttcaggcag cacttccttg acagctaaag
    57361 gaatcgattt gatgcaacgg gcgtaccata atccttcaag attagcaata gaaccatctg
    57421 ctgcaatgtg tccccatccg tctgtcatat tgaataatga agcaaaatcc tgtcctactt
    57481 ctgcttccat ttgcgaagtt gccatagaag attccaatgc aacattattt gggttccaca
    57541 gcatcgcata gttgtaagct aataaagcag gcatcaatgt ttcagcattc atttgtcccc
    57601 agtaacggcc tgctgaatgc catgggatcg atcctgcgcg taatcgctga ctgacttcat
    57661 ccaagacctc tatcatatgg tcgcgggtgg ctagataatc tggagtgagc ttatctcctt
    57721 cgctaattgc aggcatatct gaaggaatat aattttctct ccatccaaga tgttcatcta
    57781 ccatcttgtt caacaacatt ttataaactg gtccattttc agctttgtcg cctataaaga
    57841 cggccttgat atccatatct ttcatttttc ttccctccat attttgttgg tcaatgtctt
    57901 gcagatacat gtgtttatct gtaacacctc ttcactatag cgccaaaaat gagaattttt
    57961 tttttataac atcaaatcca cgtagatttt tacaaacaaa aataaataaa gtcggatttt
    58021 tctgataatt caacgcaaaa aagcgaacaa tttttcaata aatcagtctt ctaaaataga
    58081 taacctaaaa aaagcgaaca aacaaataaa atgactgtcc ttcattcact aaacatattt
    58141 ttattttttt atattgttaa aaattcgcaa tttatttttt aatagaatta tctgttttcc
    58201 aaattttata acataaaaaa ccttttttaa cggcatttat atgctttttc agaaattaac
    58261 tgatgatttc aaaaagaaaa catgtcataa tatttcccat attgtgcaaa aaaatacaag
    58321 gcggaggctc tactatgatt gaagaatata ttgagaaaaa tattttaaga cagctgtttt
    58381 tatgtgggca attctatgta aataaagaag tcaatctaga aaagctctcc aatctcctgc
    58441 atgtttgcaa aaccacttta ctcaatgata tcaataacat aaaaaaagaa tttgaagaac
    58501 agatcgctta tacacatcgg gaaaaggacc gttacacttt atatttttca gaacatatac
    58561 ctcgatgcaa gatcatgcag caattgtctc aaaattcgtt gtttttaaaa acttgtctgc
    58621 tttatttgga agaagatgaa cctgattatc ttcaattaac tgaatgtgaa ttcatctctg
    58681 tcagcaaagc ttattcatta aaaaaacaag tattagctta ttttaatgac tgcgggatcg
    58741 aaatcgaccg ctactcccct cgattcactg aaatggaaag acgtctgctg cttcttaatg
    58801 tgtcgtatcg tttaggcggt tttaattctt gggagctacc tgaatcgttt tttgaacgtg
    58861 ccgatcgttt cattgaatcc gtaacggaaa atagtggcag attttatgat aaagaaaata
    58921 aagaaatctt atcgattggt tttgctatca gtttcctacg ccagcaagtg tgtgctgtga
    58981 caatagattc aaaatttatc gaagaaatca aaaaacgtcc tatttacaat tatgtcgaat
    59041 cagcatggga aaacactgat ttccaaacct attataaaaa agaagaattc gcctttattt
    59101 tgacactatt caatctttgt aattatggtt tccattctta tcagttgatt gcggaagact
    59161 ttcaacagct acaccaagtg tttattgaca atactcccga aataaaagaa ctagttgcta
    59221 cctttgaatc tcacttcaat caagaattat tcggaaacca accgttcgaa cgtgcgctga
    59281 ttcatctgat gcgttcggct tgggataact atcaattatt catgccagaa aaattttatc
    59341 ttttaaatga ggaacagaca aatttatata aagaagtcca gacaattttt tccagctggt
    59401 ccagccagtt accttatgat ctacggttga atcctaattg catgcgggct tttgtgatcg
    59461 aattgagcgg aattctccgt ctgacaaaag aacatctgac tatctatatc gtcacaaatt
    59521 cggatgttca ttatctgatt tatcgggaag ccttggaagc tgtaactact ttcgattttc
    59581 aagttgcacc aacaatttat tcaagtatat ctgatataaa gaagtatgcg cagcagtcct
    59641 caaaccgggt attatgtgaa cgtacattat atacaccaga tgcggtccaa tatgaaaata
    59701 ttattcctat ttcgatcaat acgatcgatc gagctatcat ttcagctgtg caaaacaaat
    59761 aaggggctgt gacaaaaatc atgtcacagc ctcttatttg ttgaagatgc ccatttctgt
    59821 aacaatctct tgatacacgt caggctcaca acctcactta ttttggacat ctacgggtcc
    59881 gatctcttta tttaaaaaat aagaaatgat ggttcggata actaccaacg ccgctagttg
    59941 gaaaatatcc tgcaaggtag gtttgataat cgattcgatg atcccagctg aaacaagaat
    60001 ttccaaactt agaagtatat agcctcccaa catcttttta atagcattgt tctcgctgac
    60061 tcggtcgctt tgcacttttg tatggacaaa taaatatttc aaaaaatcct tgattgatag
    60121 acaaacaccc caaaccaata aacagatagc aaagatatca agtcccagta caagtttttc
    60181 gaaatatgga agaagaaact gcatcaactc tgtcgtcatc ctacctctcc tcttctttgt
    60241 ttttctttgt cttctatttc ctgattcaag aaataagaaa tgactgttcg aatgataata
    60301 ataagtgcaa gcttcaaaat atctgtccaa gtcggcttga taactgactc gatgatatca
    60361 gcaacgacta gtacttccaa gcttaacaaa atataacttg ctagcagttt tcttgtatct
    60421 gcattacgag tattacgttc tgcatagttt ttcttgacat gagaccaatc aaaaagtttg
    60481 aatagaacaa gaacgatccc gacaattaag ataccgatag aacaaatatt taaaatagca
    60541 atgatccatt ctagaaattc aattaaattt gagcgaaaca tatacgctac ctactttctt
    60601 ttaatttgtt cctattcttt tattgtaaaa gaaagttacc ttgttcgtct atttaaaagt
    60661 tgttctaatg ataacggttc gcttaaattt ttctttttca ctctcccatt tttctccctc
    60721 catccataaa tcgtggaagt atccaaaaca acgtagcaag ttaaaataag gcttagtccg
    60781 tcatcagctt ttcaaagaag cactgtctcg gtgctttttt tgtacccaaa tttctaaaaa
    60841 tagaaccata cacctcctca aatcttttct tcttacctac cctattttta tttacaggaa
    60901 aatcagacac ttcttctttt ttgtcaaaat ttcctttttc ttctcgtcct atcatttggc
    60961 attctaataa aaacgaacta tccttggata tagaaagaga aaacaaggag gcgtttttca
    61021 tgagtaaaaa attaatcaaa gtcggcatcg gtttaggttt gcttgccctt ggcgctgcat
    61081 atctaggaaa aaagacagga ctattcgaag atgacagtca tttatatgat gaattcgaat
    61141 caatctagca tcctatttag ttgaatcact acggacatac ttggaagaca ttggaggaat
    61201 cacaatgaga aaaagtaaag caataatgat tggtgccggt attgccaata tggcagcggc
    61261 tgtttatttg attcaagaag gcaaatggaa aggggatcag atcacctttt attcattgga
    61321 tgatcacggt tcaaatgatg gtgcaccgac cgacactgta gtggatgaat attggaataa
    61381 aaaccatcca ttagaaaacc aaaaaggcta tattgctcga ggcggtcgca tgcttaatta
    61441 ccgtacctat gtagatttga tggatctgtt aagtcgaata ccttctgtta ctgagccagg
    61501 gatgactgct gaagaagata cgagagattt tgatgcaaaa caccgaacct ttgacaaagc
    61561 acgtttgatg gaaggtggca aaggaatcat tgatggcgga aaactgggat tcaataataa
    61621 agaccgtatt cttctgacta aactgattgc tatgcctgat tcagaagaag aaaaactaga
    61681 caatatcact atcgaagaat atttcaaaga tgatccacac ttttttgaaa caaacttctg
    61741 gtttatgtgg gaaacaacat ttgctttcag aacacgtagt tctgctcaag aattgcgtcg
    61801 ctatatgcat caaatgattt atgaattcac tcaaatcgaa catctagtgg gcgtcaatcg
    61861 aacacgttac aatcaatacg aaagtattat gcttcctttg atcgagtact tgaaagaaca
    61921 aggatgcaaa atcattttga accgccgtgt cactgactgg gaattcaaag aaacaccgat
    61981 gcaagatgaa atcactgtga ctggtttgaa aattaccaat acactgactc aagaagaaga
    62041 atacgttgtg gtcgatgaag atacagcagt tattttcact aatgggtcca ttacagattc
    62101 agctacttta ggagattacg aaacaccagc tgtagaaaat atggattatg gtgcagcttc
    62161 tagtctctgg aaaaaagcca gtgaacgttt ctacaacttg ggaaatcctg acaaattctt
    62221 tgctgatcga gatgcaagcg aatgggtcag ctttaccctg acgacgaaaa accatttgtt
    62281 gttgaatgaa atcacccgta tcacgactca agaaccagga aatgccttga attcatttat
    62341 ttcaaccaca ccgatcacgc cgttaggcca aaaagatgtc aatatgtcta tcgtcgtgca
    62401 tcatcaaccg cattttacgt ctcagaaacc aaatgaaaca gttatttggg gttatttcct
    62461 ttatccaaga cgacgtggcg aatttgtgga taaacagtat attaaaatga atggaaaaga
    62521 aatgctagaa gaactgattg gacaactttc aaaagtagat cctggaccag tgaatattcg
    62581 tgaaaaagaa acagaaattt tcgacagcgt aataaataat atccctgtct atatgcctta
    62641 tgcttccgcg ttgttcaata atcgtgccaa aagcgatcga ccaaaagtca ttcctaaaca
    62701 ttcgaccaat ctggccttta caggagaatt tgtcgagcag ccttatcaga tgatctttac
    62761 tgaacaaagt gctgtacgtt ctggagaaat cgctgctttc cattttgcgg gtattcctat
    62821 gtcccgtctt gtcaaaacac cgcgttacga caaagatatt cctactctag ctcgtgccgc
    62881 aaaaaaaatg tttgaataat caagaggttg tgaaaaagct gccctgcatc aagtaataag
    62941 aacaaccagg ctaaaacagc ttcttatgtt tttgatttgg ttggacttat taccgcagat
    63001 gcaagctttt gaacaccgtt taccaagagg ttgtgaaaaa gctgccctgc atcaagtaat
    63061 aagaacaccc aagctaaaac tgcttcttat gtttttgact tggttggact tattaccgca
    63121 gatgcaagct tttgaacacc atttaccaag aggttatgaa aaagctgccc tgcatcaagt
    63181 aataagagca gccaagctaa aacagcttct tatgtttttg acttggttag acttattacc
    63241 gcagatgcaa gcttttgaac accgtttacc aagaggttat gaaaaaggcg tttagtttcg
    63301 agtatgaaga aaaattttgt gaaaatggtt cctcacgttt ttgcataaat ttgacttaat
    63361 accgagaaac tgatcccttc tgtcataacc tctttttatt tatgtctgtt tctttttgaa
    63421 aacaactatt ttttcaacgt ttactctctt gccaatccaa catcatctaa cggatacaac
    63481 tatttcaatg attaccatta cactaaaaaa tcggaaacac acctctccga acacaaatac
    63541 ataagactat agaatgtttc atttaagaaa aaaagcgttt cattatcaaa aaggtaagat
    63601 ctcctttaaa atgaaattat ctgtagtact aataatgcag acaattttat gaatctgaaa
    63661 ggagcatctc caatgaaagc agtcacttgg caaggaaaac agaaaatgga aatcagaaac
    63721 gtagatgatc caaaaatatt agaaccaaca gatgcaatca tccgtatcac agcaacagcc
    63781 atttgcggct ccgatctgca tctttaccat catggtgaag cagttttgga aaaagggtat
    63841 gttgtaggac acgaaccaat gggaatcgtt gaagaagtgg gatctcaagt tcaaacattg
    63901 aaaaaagggc aacgtgtggt tatccctttt aatattagtt gtggtcattg tcatttctgc
    63961 ctgaatcaca tggaaagcca atgtgatgaa tcaaatccag atcagttata tggcgggctt
    64021 ttcggatttg gcaagttgaa cggtaatcat tggggtggtc aagcggaata tctaagagtt
    64081 ccttatgcag actctacttc atttgttgta ccagataatg atcttcctga tgaaaaagtt
    64141 ttatttctat cagatatttt gcccacagct tattggagcg ttgaaaacgc aggagtaaaa
    64201 aaaggcgata cagttgtgat tctaggttct ggtccagtcg gtctattcgc tcaaaaattc
    64261 gctgttatgg ctggagcaga gcgcgtaatc gcagtagatc cagtacagca ccgtctagat
    64321 aaagcggcta attacaatgg ggttgaaact tatttcttag aagacacggc acaagctgga
    64381 acagaattgt atgaactggc taaaggtggc gcagatgtca ttatcgattg tgtaggaatg
    64441 gacggattag agcctgtcaa agaaaaagcg aaaaatttag taagcttaca aagcggcaca
    64501 atctctccat tacagatggc atcgcaagct gtcaaaaaat ttggaacagt ccaagtaact
    64561 ggtgtttata tgactccagc ttcttcttac ccgctgcaag aattttttat gcgggatatc
    64621 gctgtcaagc atggacaggc accaattatc catctaatgc caaaaattta cgcaatgatt
    64681 gcagaaggac tattcgatcc tacacaaatc attactcatt cgctgccact atcagaagca
    64741 gcacaagcat atgagatctt tgacaaaaaa gaagataaaa atataaaagt tgttttgaaa
    64801 ccttgaattc agtaaaaaat acaggtgatt ttctttatgc ccaaaatcaa acgaaatacc
    64861 catgagatcg aaataggaaa agaagaagat atcgaaatac gaggacgtcg cttccgcttc
    64921 tatttccaaa atcgttacac attgatctca ctggctgtcg atttattaac cgggattttc
    64981 tatatttttg gaagccttgc ttccttaact aaaatccccg atcgatatgg cacctatttt
    65041 tatttggctg gtgctatttt cttgacgatt cgtcctattc tcagaatcgt aaggaacatt
    65101 tttatttacg acgaaaaaaa agcaatgaag agaacaagca aaaaaaaaga ggcatgagaa
    65161 tttttcaaat ctcatgcctc ttttttcacc ctatcgtatc actttgatac agacgagcgg
    65221 tcgtcccact ttcttccttg accattgtca aaaatgtcca ctcgtatcgt tcataaaacg
    65281 tggtatgatc tgtaattaag taaagttttt cgtacccaag ttgatgcatt tcttttctga
    65341 tttccgctaa tatccgcttg gctatcccct gcttacgctt ttccggttca acaaacaggg
    65401 cacaaagatt tggtgtcaga tcagggcggt tatggaagtc gttttcaatg acgcccgctc
    65461 ctccgacgat ggtttctttt tcatctaaga ccacatacca ttgaggaata ctttccttat
    65521 tagcgattcc agtacgaata ctttcctcat acacaacagc aggaactccc cattttgatg
    65581 aaaaccaatt cgcgctttgt tttactaatt ctgggtgttc tcttaatttg atccagttat
    65641 atgtaaccaa tgtttaaacc tccgactaaa ataaaacgtt tacaaaaatt atacaagtct
    65701 ttatgaaaat tagcaatgac aacaatagtg atgtaaaaaa aaaacggaaa acaatcactt
    65761 gttctccgtt ttttgattaa tcaagcatct aaagcttctt ttcttctttc ttggatcgta
    65821 gctaccttga cgaacggtag atagatcaaa atagaaagaa ccaaattgac agcggctagt
    65881 acaccacctg caatactttt tgttgccaat acaccgccaa taattggtgg agttacccat
    65941 ggaggcataa cggtagctgc tggcactaaa cctgtagaag tcgcaaagta agcaacacta
    66001 actaagacca ttggtgtcaa aataaatgga atgaacatga tcgggttcaa cacgataggt
    66061 aacccaaaca tcgttggttc attaatattg aagacacctg gcgcaatcga caagtttgtt
    66121 acaaccatat atggtttgtt tttacgtcct actaaataaa tagctaacag taaacctaaa
    66181 gttgcacctg ttcctcctaa gttgacaaag ctgtcaaaga aaggtttgtt cacgataaac
    66241 ggtgcgctat gcccagctgc gattgcatta acgtttgctt caatggctgg cgcattgatt
    66301 gtttgcatca aaggatcgac catattcgct ccgtgtaaac caaagaacca taagaatggt
    66361 gtgataaatg caagcagtaa ggcagatgga taagagtttg caagtcccat aaatggttct
    66421 tggaccactg tatagaaaga acctacgata tcatcaacac cgaatgcagc aaaaattgca
    66481 gcaactaaag caaacgcaga gatagtgatc attgctggta gtaatgaagc aaatgctttt
    66541 gcaactgccg gtggcacacc atcaggcatt ttgatgatca atttttcatt tccgcttaaa
    66601 cgtacaaaga tttctgttga aataatccca acaataatag caataaacaa accgtttgag
    66661 ctcataccta atgctccgcc taaagcgaag aaagagccta aagaaatcac acctgcggaa
    66721 acaccgtctt ttcggtagcc gttagctaaa tgataagcaa gcaagaaagc aatcaagaca
    66781 gaaagaatgg caaatgtacc gttccaagca gcagccccga atcctttcca tgattcacca
    66841 ccaaaaattg agttcatcaa ttcttggaac ccgggaatcg gtaagttatt gatcattact
    66901 gctaatgctc ctaagatcat taacggcata ctcaccataa atgagtcccg aatcgcaact
    66961 aaatgccgtt gtgcaccaat ttttgatgct acaggtataa aatgtttctc cataaatgca
    67021 acaaatttat ccataaatct tccctctttt ctttactgta gattacgcgt tcaatcgacg
    67081 atacagatca atgatctctt ttgctaaatc tgtaaaagct atagatgtca tcagatgatc
    67141 ttgactgtgg accgtcaaaa gcgtgacttc aacgtgattt ccttgtgctt cttgtgtcag
    67201 catctctgtt tgagagtgat gtgcttggac taaagattcc tctgcatctt tgattttttc
    67261 atctgctaaa gtgaaatcac cttttttcgc agcagcaatc gcttccattg catcgctttt
    67321 tgcatttccg ccaaacatga tcagacccat gatggcttct agattttttt gatcttccat
    67381 ttattgtatc ctccgataat ttttattatt tgtttattag tttttctgct tggtcgagta
    67441 ctttttcacc attcatcatg ccatagtcag ccatattgat tacatctaaa ggaatgcctt
    67501 taggtgctag cttttcagca aattgatttt gcataaagcg tacttgcggt cctaaaagta
    67561 aaacgtctac atttttagat tctagttgat tatccgcatc tgaagcagat acagcaaaga
    67621 tgtctgcttc cattcctttt gcttctgctg ccttttgcat ttttgtgact aggagacttg
    67681 tactcattcc agctgaacat acaagcatga ttgttttctt ttccatttta aacacgttcc
    67741 tttctatact tacacttgta tataagcaag tagcgtgcca actttaaaag cgctttaaaa
    67801 agttgatatc atcacattta aggtctatac caagttgcat acacactaaa aaagaaagcg
    67861 cacactaaac acacaaatta atttttatta ccttttttct tttaacgtgc acaaaaaaag
    67921 ttgtgacaca aaacttgtca caactttttt caaataaacg gtattcaaaa gcttgcatct
    67981 gcggtaataa gtccaaccaa gttaaaaaca taagatgttg tttttacttt gctattctta
    68041 ttacttgatg caggacagct ttttcacaac ctctcaataa acggtgttca atcagctgac
    68101 cctgggtatt agctcaaaac gctggattca caacctcttt tatttcaaat aaccagtaaa
    68161 tacaatgaac atctacaaaa aacttctatt tatttataga tttcgtcagg caaatccaat
    68221 tctctcttat caatcaaagt ctgataccac gaagcagatt ttttcaatgt tctgcttcgt
    68281 tcatcgttca attcgattcg aactaatcca tatcgattct taaatgcatt cattggtgac
    68341 acacagtcag tgaatgccca taacatatag ccttcgcaat ttgcgccttc ttctgttgct
    68401 ttgatcaagt aatgcaaatg ctgtccgata aattcgatac ggtaatcatc ttgcacgatt
    68461 cctttctcat ccatatactg ttcttcatat tctcttccca taccgttttc tgttatcagc
    68521 caagggatat tatgataatt ttcttttaga tacatggcta tatcatacat gattttcgga
    68581 tagatttccc atcccctgga attattcatt ttcttcccag gtaaatcaaa gacttcataa
    68641 tatcgttcag gatggaaagg tgtctcttca ttccattgat aacgaggggc gcgaacgcgt
    68701 ttaggataat attgattgat tccaaggaaa tctactgtat gatgctgaat cgtttctaaa
    68761 tcctctgttg caggatcgaa ataaatcgat tgtttttgac acaactccag gaactcttct
    68821 gtgtagtatc cttttaccat cggatcaaaa aatactcgat tataaaacaa atcatacata
    68881 taagcagctt tttggtcttc tggagaattg gatcgagcat agaccatttc aggatttaaa
    68941 atacagccaa tccttccacc ataatttccg ctgcggtaaa tctctactgc tttagccgtt
    69001 gctaaaactt tatgataatt ccacatcatc cacttttttg tgttttgttc atgcggccag
    69061 cgaacagcat ccaaatagca acgcgtttgg ggaacgattg gttcgttgaa tgtaaaccag
    69121 ttttttaccc tatcaccgta acgatcaaag gcaatttgag catacttagc ataaaaatca
    69181 actacttttc ttgaagacca gccatcatat ttttccaaaa gaaaagctgg gacttcataa
    69241 tgttccaaac aaatcatcgg ttctacgtct gcttcgatca aagagtcgat catttcactt
    69301 atatgctgag catattcttc atctactata cagttctcat aatcagtaaa aaaacgagcc
    69361 caattgatag aagtccgata atgtgtcaga tggatggatt tcatcagatc cacatcctgc
    69421 tggtattgtt ccataaaatt agttgctacg gctgggccat acccattatg ccaaacaaaa
    69481 tgttcatttt tataccagct atctataaac gaatcctgtc cttctttttt tcctttccaa
    69541 ccttccgttt gccaagcaga agatgcagca ccaagaataa aattttttgg aatagtaatt
    69601 ttcatgattt cctcctgttt tttagatccc atcattttcc acacgatttg ctacttttac
    69661 aaatggcaga tagatcaaaa tagaaacaat aatacaaaca agttgcgtaa taactgcacc
    69721 gatatttcct gctgttgcca gataagcatt gacgatcggc ggcattggcc aagggaccat
    69781 tacaactgct ttcgccgcaa atcctaaagc ggttgcaaaa taaccaatcg ttccagtgat
    69841 aagaggcgtt aagataaacg gaatagctaa aattggattc agcatgatcg gcataccaaa
    69901 aataactggt tcattgatgt tgaagatccc aggagcaagg gataacttgg tgatttgttt
    69961 catatcttcc cgttttccaa ctaacaatac tgcaatcagt aaaccgatcg tgactccaga
    70021 cccgcccata ctcatataca tatcccaaaa tggcatagta ataatgttcg gtacttcttt
    70081 tccagcttca aaagcttccg tatttacagc aattgccgct aaaagcaacg gttcccgtat
    70141 cggcttcacc atttgatttc catggatacc aatcacccaa aagacttgcg caataaacat
    70201 caatagcaaa atacccggta acccttgtac gacaccttct aatgggcgtt gtacgacatt
    70261 gtaaatgata tcataaaggt acattcctgt aagttctttg atgataaatc ccgcagccgc
    70321 gatacccgat acagtcagaa tcgtcgggaa taaagcagaa aaactagcag aaacattcgt
    70381 tggcacggta tcaggcattc tcagctgtag tttcttctgt ttcctcaacc agcaataaag
    70441 ttcaatagaa aggatggaga ccaacattcc caaaaataac cctttcgtat ctgtatattg
    70501 tttagccaat acgttttcta ctataacagt ctgattttca ttcactaatt cataaacagt
    70561 tggattaaca gataaataag acatcactgc gatgatacca gggaatacac catccacttt
    70621 attcagcttg gctaattcga tccctatcag aaaaacagca tagatggtca agaaacttag
    70681 tgtgacatag ctgatggcag atgcgatagg ctttaattct tctaaaaaac gcaagaaact
    70741 tatctgtgct aagccatttt ccgagtcaaa gaccattgct gaaaacaatg tgccaaaagc
    70801 acccgtaata attaccggaa tcaatgcagc aaatgcgttt tttatcacca tgatatacct
    70861 taaattattg attctcgttg ccacgttccc taaaacattg gctaatttat ccataaaact
    70921 cattccagat cccctcattc ctgcttcttc tccttgacgt catctctttt tgtctattag
    70981 tcagcgctta catttcgatg aacagaaact atttactcct cttttttacc aaatataaaa
    71041 caaaaattca tctgatgtat ttatcataaa atacatcaga tgaactgtca attagtttct
    71101 ttttctccta ttattttctg taattctctc cgatttattg ccatatggac agtcattgca
    71161 tcaaacgcag caagtgcatt ccgcctttcg atggcctgaa cgatctctgt atgaatatcg
    71221 atcgtctcga ttttcagatg ctggatatca taatttttat taaacaaagc aattgattca
    71281 ttaatgattg ggataatatg cagcaaggct acgtttccgc tagcttctgc aatcatcgta
    71341 tgaaaatcga tgtctaattg aacatgttct tgtgtgcctt ctcgaaaaga agtttcaatc
    71401 ttttgcgtta attttttcat ttggacgatt tgattcttcg ttgcatattc cgctgccaaa
    71461 cctgccatct taggctccaa taaatatctc agttcaaata agtctcgtat catccgatcc
    71521 tgatcttcaa tcaaagaaaa accgagtggg tcattggcaa tccctcgctt atcactgaca
    71581 aatgtccccg ctccttgccg aacttcaagg atattcctgg aagctagagc ccgcacagct
    71641 tctcgcaccg tgcttcgccc cacctctaaa taatcggaca attcatattc attcggcagt
    71701 ttatctccta cttgcaactg catttccttt aaatatctaa ggatcttgtc agtagttact
    71761 tctactaggg ttttattttc ttccaaacca catacctcct tttcatctga tgtatttttt
    71821 cgtaattatt ataacacgtt tgaatcatct gatgattttt tgtatacaaa attgattaat
    71881 ccgttcatag acatacaaac gaagaagata tttaccataa aaaagactag gataaa
//
LOCUS       DAYYEF010000007        65358 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000007 DAYYEF010000000
VERSION     DAYYEF010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.007"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            476..1339
                     /locus_tag="ACHA1B_000584"
     CDS             476..1339
                     /locus_tag="ACHA1B_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFM8701375.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="ACHA1B_000585"
     CDS             complement(1468..3090)
                     /locus_tag="ACHA1B_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFM8701376.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="ACHA1B_000586"
     CDS             3339..3860
                     /locus_tag="ACHA1B_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFM8701377.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACHA1B_000587"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="ACHA1B_000587"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047112 - pyruvate oxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HFM8701378.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="ACHA1B_000588"
     CDS             5941..6759
                     /locus_tag="ACHA1B_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HFM8701379.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="ACHA1B_000589"
     CDS             complement(6862..7059)
                     /locus_tag="ACHA1B_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701380.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="ACHA1B_000590"
     CDS             7228..7806
                     /locus_tag="ACHA1B_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFM8701381.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="ACHA1B_000591"
     CDS             7901..8038
                     /locus_tag="ACHA1B_000591"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701382.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="ACHA1B_000592"
     CDS             complement(8851..9354)
                     /locus_tag="ACHA1B_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFM8701383.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="ACHA1B_000593"
     CDS             9713..10738
                     /locus_tag="ACHA1B_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFM8701384.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11061..11939
                     /locus_tag="ACHA1B_000594"
     CDS             11061..11939
                     /locus_tag="ACHA1B_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase domain-containing protein"
                     /protein_id="HFM8701385.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12415..12531
                     /locus_tag="ACHA1B_000595"
     CDS             12415..12531
                     /locus_tag="ACHA1B_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFM8701386.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13459..13797
                     /locus_tag="ACHA1B_000596"
     CDS             13459..13797
                     /locus_tag="ACHA1B_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701387.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13891..14121
                     /locus_tag="ACHA1B_000597"
     CDS             13891..14121
                     /locus_tag="ACHA1B_000597"
                     /inference="COORDINATES: protein motif:HMM:NF042636.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6568 family protein"
                     /protein_id="HFM8701388.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14521..14892
                     /locus_tag="ACHA1B_000598"
     CDS             14521..14892
                     /locus_tag="ACHA1B_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HFM8701389.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15166..15858)
                     /locus_tag="ACHA1B_000599"
     CDS             complement(15166..15858)
                     /locus_tag="ACHA1B_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM8701390.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15861..16646)
                     /locus_tag="ACHA1B_000600"
     CDS             complement(15861..16646)
                     /locus_tag="ACHA1B_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFM8701391.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16883..18283
                     /gene="lacG"
                     /locus_tag="ACHA1B_000601"
     CDS             16883..18283
                     /gene="lacG"
                     /locus_tag="ACHA1B_000601"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033920 - 6-phospho-beta-galactosidase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HFM8701392.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18308..18625
                     /locus_tag="ACHA1B_000602"
     CDS             18308..18625
                     /locus_tag="ACHA1B_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HFM8701393.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18638..20311
                     /locus_tag="ACHA1B_000603"
     CDS             18638..20311
                     /locus_tag="ACHA1B_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HFM8701394.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20325..21956
                     /locus_tag="ACHA1B_000604"
     CDS             20325..21956
                     /locus_tag="ACHA1B_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-beta-1,4-galactanase"
                     /protein_id="HFM8701395.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="ACHA1B_000605"
     CDS             complement(22447..24012)
                     /gene="guaA"
                     /locus_tag="ACHA1B_000605"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016462 - pyrophosphatase activity
                     [Evidence IEA];
                     GO_process: GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HFM8701396.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(24071..24994)
                     /gene="coaA"
                     /locus_tag="ACHA1B_000606"
     CDS             complement(24071..24994)
                     /gene="coaA"
                     /locus_tag="ACHA1B_000606"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004594 - pantothenate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HFM8701397.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            25190..25795
                     /locus_tag="ACHA1B_000607"
     CDS             25190..25795
                     /locus_tag="ACHA1B_000607"
                     /EC_number="2.1.1.172"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0052916 - 23S rRNA
                     (guanine(1835)-N(2))-methyltransferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM8701398.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            26103..27119
                     /locus_tag="ACHA1B_000608"
     CDS             26103..27119
                     /locus_tag="ACHA1B_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8701399.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            27260..28561
                     /locus_tag="ACHA1B_000609"
     CDS             27260..28561
                     /locus_tag="ACHA1B_000609"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016154 - pyrimidine-nucleoside
                     phosphorylase activity [Evidence IEA];
                     GO_process: GO:0006213 - pyrimidine nucleoside metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HFM8701400.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            28607..29269
                     /gene="deoC"
                     /locus_tag="ACHA1B_000610"
     CDS             28607..29269
                     /gene="deoC"
                     /locus_tag="ACHA1B_000610"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004139 - deoxyribose-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0009264 - deoxyribonucleotide catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HFM8701401.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            29290..29688
                     /locus_tag="ACHA1B_000611"
     CDS             29290..29688
                     /locus_tag="ACHA1B_000611"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004126 - cytidine deaminase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009972 - cytidine deamination [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HFM8701402.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            29754..30836
                     /locus_tag="ACHA1B_000612"
     CDS             29754..30836
                     /locus_tag="ACHA1B_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM8701403.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            31048..32610
                     /locus_tag="ACHA1B_000613"
     CDS             31048..32610
                     /locus_tag="ACHA1B_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701404.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            32603..33736
                     /locus_tag="ACHA1B_000614"
     CDS             32603..33736
                     /locus_tag="ACHA1B_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8701405.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            33736..34692
                     /locus_tag="ACHA1B_000615"
     CDS             33736..34692
                     /locus_tag="ACHA1B_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8701406.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            34791..35957
                     /gene="deoB"
                     /locus_tag="ACHA1B_000616"
     CDS             34791..35957
                     /gene="deoB"
                     /locus_tag="ACHA1B_000616"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008973 - phosphopentomutase activity
                     [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA];
                     GO_process: GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HFM8701407.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            35981..36799
                     /locus_tag="ACHA1B_000617"
     CDS             35981..36799
                     /locus_tag="ACHA1B_000617"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFM8701408.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            36816..37523
                     /gene="deoD"
                     /locus_tag="ACHA1B_000618"
     CDS             36816..37523
                     /gene="deoD"
                     /locus_tag="ACHA1B_000618"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HFM8701409.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="ACHA1B_000619"
     CDS             complement(37821..38507)
                     /gene="gpmA"
                     /locus_tag="ACHA1B_000619"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFM8701410.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(38679..39260)
                     /locus_tag="ACHA1B_000620"
     CDS             complement(38679..39260)
                     /locus_tag="ACHA1B_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8701411.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="ACHA1B_000621"
     CDS             complement(39393..40076)
                     /gene="rpiA"
                     /locus_tag="ACHA1B_000621"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HFM8701412.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            40395..40808
                     /gene="rpsL"
                     /locus_tag="ACHA1B_000622"
     CDS             40395..40808
                     /gene="rpsL"
                     /locus_tag="ACHA1B_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HFM8701413.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            40892..41362
                     /gene="rpsG"
                     /locus_tag="ACHA1B_000623"
     CDS             40892..41362
                     /gene="rpsG"
                     /locus_tag="ACHA1B_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HFM8701414.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            41456..43543
                     /gene="fusA"
                     /locus_tag="ACHA1B_000624"
     CDS             41456..43543
                     /gene="fusA"
                     /locus_tag="ACHA1B_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HFM8701415.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            43715..44902
                     /gene="tuf"
                     /locus_tag="ACHA1B_000625"
     CDS             43715..44902
                     /gene="tuf"
                     /locus_tag="ACHA1B_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HFM8701416.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            45309..45617
                     /gene="rpsJ"
                     /locus_tag="ACHA1B_000626"
     CDS             45309..45617
                     /gene="rpsJ"
                     /locus_tag="ACHA1B_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HFM8701417.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            45648..46277
                     /gene="rplC"
                     /locus_tag="ACHA1B_000627"
     CDS             45648..46277
                     /gene="rplC"
                     /locus_tag="ACHA1B_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HFM8701418.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            46305..46928
                     /gene="rplD"
                     /locus_tag="ACHA1B_000628"
     CDS             46305..46928
                     /gene="rplD"
                     /locus_tag="ACHA1B_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HFM8701419.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            46928..47218
                     /gene="rplW"
                     /locus_tag="ACHA1B_000629"
     CDS             46928..47218
                     /gene="rplW"
                     /locus_tag="ACHA1B_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HFM8701420.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            47257..48090
                     /gene="rplB"
                     /locus_tag="ACHA1B_000630"
     CDS             47257..48090
                     /gene="rplB"
                     /locus_tag="ACHA1B_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HFM8701421.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            48133..48411
                     /gene="rpsS"
                     /locus_tag="ACHA1B_000631"
     CDS             48133..48411
                     /gene="rpsS"
                     /locus_tag="ACHA1B_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HFM8701422.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            48434..48781
                     /gene="rplV"
                     /locus_tag="ACHA1B_000632"
     CDS             48434..48781
                     /gene="rplV"
                     /locus_tag="ACHA1B_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HFM8701423.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            48795..49451
                     /gene="rpsC"
                     /locus_tag="ACHA1B_000633"
     CDS             48795..49451
                     /gene="rpsC"
                     /locus_tag="ACHA1B_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HFM8701424.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            49454..49888
                     /gene="rplP"
                     /locus_tag="ACHA1B_000634"
     CDS             49454..49888
                     /gene="rplP"
                     /locus_tag="ACHA1B_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011375443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HFM8701425.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            49878..50066
                     /gene="rpmC"
                     /locus_tag="ACHA1B_000635"
     CDS             49878..50066
                     /gene="rpmC"
                     /locus_tag="ACHA1B_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HFM8701426.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            50091..50357
                     /gene="rpsQ"
                     /locus_tag="ACHA1B_000636"
     CDS             50091..50357
                     /gene="rpsQ"
                     /locus_tag="ACHA1B_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HFM8701427.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            50415..50783
                     /gene="rplN"
                     /locus_tag="ACHA1B_000637"
     CDS             50415..50783
                     /gene="rplN"
                     /locus_tag="ACHA1B_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HFM8701428.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            50820..51128
                     /gene="rplX"
                     /locus_tag="ACHA1B_000638"
     CDS             50820..51128
                     /gene="rplX"
                     /locus_tag="ACHA1B_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HFM8701429.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            51156..51695
                     /gene="rplE"
                     /locus_tag="ACHA1B_000639"
     CDS             51156..51695
                     /gene="rplE"
                     /locus_tag="ACHA1B_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HFM8701430.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            51714..51899
                     /locus_tag="ACHA1B_000640"
     CDS             51714..51899
                     /locus_tag="ACHA1B_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HFM8701431.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            51935..52333
                     /gene="rpsH"
                     /locus_tag="ACHA1B_000641"
     CDS             51935..52333
                     /gene="rpsH"
                     /locus_tag="ACHA1B_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HFM8701432.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            52365..52901
                     /gene="rplF"
                     /locus_tag="ACHA1B_000642"
     CDS             52365..52901
                     /gene="rplF"
                     /locus_tag="ACHA1B_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HFM8701433.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            53062..53418
                     /gene="rplR"
                     /locus_tag="ACHA1B_000643"
     CDS             53062..53418
                     /gene="rplR"
                     /locus_tag="ACHA1B_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HFM8701434.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            53439..53939
                     /gene="rpsE"
                     /locus_tag="ACHA1B_000644"
     CDS             53439..53939
                     /gene="rpsE"
                     /locus_tag="ACHA1B_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HFM8701435.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            53954..54133
                     /gene="rpmD"
                     /locus_tag="ACHA1B_000645"
     CDS             53954..54133
                     /gene="rpmD"
                     /locus_tag="ACHA1B_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HFM8701436.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            54177..54617
                     /gene="rplO"
                     /locus_tag="ACHA1B_000646"
     CDS             54177..54617
                     /gene="rplO"
                     /locus_tag="ACHA1B_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HFM8701437.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            54617..55912
                     /gene="secY"
                     /locus_tag="ACHA1B_000647"
     CDS             54617..55912
                     /gene="secY"
                     /locus_tag="ACHA1B_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HFM8701438.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            55974..56621
                     /locus_tag="ACHA1B_000648"
     CDS             55974..56621
                     /locus_tag="ACHA1B_000648"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA];
                     GO_function: GO:0019205 - nucleobase-containing compound
                     kinase activity [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HFM8701439.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            56812..57030
                     /gene="infA"
                     /locus_tag="ACHA1B_000649"
     CDS             56812..57030
                     /gene="infA"
                     /locus_tag="ACHA1B_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HFM8701440.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            57063..57179
                     /gene="rpmJ"
                     /locus_tag="ACHA1B_000650"
     CDS             57063..57179
                     /gene="rpmJ"
                     /locus_tag="ACHA1B_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HFM8701441.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            57197..57562
                     /gene="rpsM"
                     /locus_tag="ACHA1B_000651"
     CDS             57197..57562
                     /gene="rpsM"
                     /locus_tag="ACHA1B_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HFM8701442.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            57590..57979
                     /gene="rpsK"
                     /locus_tag="ACHA1B_000652"
     CDS             57590..57979
                     /gene="rpsK"
                     /locus_tag="ACHA1B_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HFM8701443.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            58059..58997
                     /locus_tag="ACHA1B_000653"
     CDS             58059..58997
                     /locus_tag="ACHA1B_000653"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HFM8701444.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            59025..59405
                     /gene="rplQ"
                     /locus_tag="ACHA1B_000654"
     CDS             59025..59405
                     /gene="rplQ"
                     /locus_tag="ACHA1B_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HFM8701445.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            59677..60516
                     /locus_tag="ACHA1B_000655"
     CDS             59677..60516
                     /locus_tag="ACHA1B_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFM8701446.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            60492..61361
                     /locus_tag="ACHA1B_000656"
     CDS             60492..61361
                     /locus_tag="ACHA1B_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HFM8701447.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            61351..62148
                     /locus_tag="ACHA1B_000657"
     CDS             61351..62148
                     /locus_tag="ACHA1B_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HFM8701448.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            62351..63097
                     /gene="truA"
                     /locus_tag="ACHA1B_000658"
     CDS             62351..63097
                     /gene="truA"
                     /locus_tag="ACHA1B_000658"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFM8701449.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            63761..63955
                     /locus_tag="ACHA1B_000659"
                     /pseudo
     CDS             63761..63955
                     /locus_tag="ACHA1B_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(64143..64919)
                     /locus_tag="ACHA1B_000660"
     CDS             complement(64143..64919)
                     /locus_tag="ACHA1B_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFM8701450.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            65042..>65358
                     /locus_tag="ACHA1B_000661"
     CDS             65042..>65358
                     /locus_tag="ACHA1B_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HFM8701451.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLL"
BASE COUNT        20740 a        11667 c        13804 g        19147 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacat cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacactt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt gtttatgatg gtaactgaat
    10921 aaactttcct gagatggtca atgctttcct tgaaagtctt acagatattc tttcttcata
    10981 gaaagtttaa gttttatagt tagtgtacaa taaaagtatg tttataccat atggtgtccg
    11041 gataatcagt catttaaaca atgaggttca aagatatgaa aaggggaaat ttgatgaaga
    11101 aaataagcaa tgaaatccaa attctggcag aaactttaac tcttcccaaa gtcgttatag
    11161 agcaaatgat tgtacaagca aaaaacatcc ttgatgaggt gtttgagcaa tatagtcatg
    11221 aactaatgga tcctaataaa gcaaaggcga ctgcaaagaa aatagacaaa gtctatgaag
    11281 aggaaccttt tgcagcatta gctatttatc tatatgcagc ttctcaaagt tggaaaaaaa
    11341 tttatcaacc attgaagatt ccaagaacta tctatttggc aacaatgaat gcttttacta
    11401 gatttattca tgaacatttc caagtaacag gaagctatcg ctttgaccgt ggtttttgga
    11461 tttggcatta cactagtggc ttgatctttc ggattggtga attggagtac gaaatgacat
    11521 attttccgaa agggtacacg gatctaagat tagaaggaaa gcagtgcctt tctcttcata
    11581 ttccttccga tgcagattta tctcagaata agataagaga tagttacgaa agtgccattc
    11641 gtttttttga actttatttt cctgattacc attaccaagt gatgtacaca gatacttggt
    11701 tactatcacc caatcttact aaatggttga aaaaagagtc aaaaatctgt ctttttgcag
    11761 ccgattatcg attattatca gttgatgaac aggacgatag tggagtccct tggatctttg
    11821 gacgagtaga tgcccaaata catgattatc cagaaagtac gagtttacag cgacaagcaa
    11881 aagagcaatt gcttgcaggc gagcacattg gctctggctt aggtattctt acttcataag
    11941 tttagtactt cgaaatagtt taaaagagcg tgagacaaaa gtaaagaaca cttttgtctc
    12001 acgctctaaa cacgtataaa cggcggaagc agaagcaact ccttcggaaa taagctgaaa
    12061 ttcacaaaaa tttgaaaagc aattttcgtg aatttcttct tatttcttgg agttaaacgc
    12121 ttctgtccca gcctcttttt tagtgttcta tcgaacacac agtacgttca ataggtaaac
    12181 tagctataac aatagatatt aaagttaacg gacaagaggg ccttttttag gtagctaaaa
    12241 cgtaataatg aaaatttatt tccagagata ggagtcaatc agctagtctg atcgactgtt
    12301 ttaacaagtt gactttcatt ttaacttttg ataccattta aaacacaaat cgtaattgtt
    12361 tcgatttgtg ttttttagca tgactacaat caaagaagaa agtgggtcgt ccatatggaa
    12421 aaaacagata tctcaagtgc ataccgccgc ttgaaaagcc caaatatcaa aacacgaaaa
    12481 cgtgcgctga agatcatcaa agatgtgaaa cggaatagtg ggaaaaggta agaagaagga
    12541 aacttaatta aaaaaatagc cgaaaaacgt ttttcggcta ttttcaataa tcggtttttg
    12601 tgtaaggttt ccgaaagaac tgctgttgat tttccatttt taacatatga taaattggta
    12661 gaatctttct tttcaaattg ataccattcc ctaattccag ttatatagtt aactacagaa
    12721 ccacaaagca cgtacgttta taaaagtatt atctgtagtt atttttcaat tccctttcaa
    12781 cctcttattt tgaccagtag tattgatcac tttacctttt aacacctttg ttcgtttttg
    12841 aaacattttt agtcaagaat ggaaacgtaa ctacataatc aaaggttttg cgaaatattt
    12901 catgaaatat ttcatgtaga agcgagcaat acggttgcaa ataaccatta tcgtttaata
    12961 agcagttacg aaagctccca atatctctaa cgttcagctc actccatttc ttttcttcaa
    13021 aaaaatcagc gattcgtatc tctttctatt tgtcgaaaaa gttaacttta aaaagtaacg
    13081 ccgaaaaaat atgcaaaaaa ataaaaaagc agttactatt gctagaataa catcaaggaa
    13141 taataagttt tggttttcag ataatagtcg ataagttgtg tattggaatt ttagatacag
    13201 taataaagta tttttcatga aattttgtga gaatcactat tacaagtatc tttaataaaa
    13261 ttaatggtta aggaggaact taaagtagaa tgtaaatgaa tagttgtagt cagtcgattg
    13321 tgatactaga ctcaaagttg caggaataag tttttcaatt tgtgattgga agataaaaaa
    13381 tgaaaaagaa gggctttttt ttatactttg ttgattgtag tgtttatttt ccctctgttt
    13441 agccaagtaa cattttctat gactcaacca gtttcaagtg aggaacatga taaccttttt
    13501 cgtgctacag aagagtttaa gaaatatcag gaaaatattg ttccggagac tccattagct
    13561 agtgagccaa ttactgatat tgatggaaac caaataggat ggtatataca gtacgaagtt
    13621 atggtggtaa ataatgactc aatagtaaaa aatacagtag gcttagagct aacaccgatt
    13681 gaaaaggtga gttcattgtt aacgtatatt tatactgatg aaagtgacga gactgagatc
    13741 attttaacgg attactcaaa aattgctact gataaaaagt atatattgtg gatgtagaca
    13801 ctagtgaaat actttatgat atagaaattg atgaaaattt actagatgta gcacaagaaa
    13861 tcgatcatca aaagcaggaa gctattcgat atgctggtag aaaagggaaa agaaaatatt
    13921 tattacgtga atgtagcaaa agttagagaa gatgaaaatg agtggaaaga attcaagagt
    13981 cgctactcaa ttaactcgac tccgacattt acagtttaca gagaaggatc gatagaaaaa
    14041 actgtttttt ggactaaaga aagtggaatg tctttagctg aagtagaaga gtttttggat
    14101 tatgttagta tgcaacagta agggagttct tattatgaaa aattttgaca catattatgt
    14161 tattgttttt tcgatatctt tgctgttaat attactaact ttaatgcagt ataaagagta
    14221 tccagagtat tttattttaa cttttgtata tttagtaagt agctacacac ttctatataa
    14281 attcagaagt tcttctagag tttctaaagt ttgtttctta attagcttat tgattctata
    14341 atatttttga tttatatagg aaattaaaaa tattatagaa tcaacactca gagaacgggt
    14401 tggtttttaa tagatttaat aagtactgat aatgaaattt ctcctggttg ggaaaacgaa
    14461 gttggttacc ctgtagaaga attttttcaa gattactttg cggagtatgc cgataggata
    14521 atgagagatt acgtaacaga taaaactcaa gaagtcatca atcaatccca gtcattaaat
    14581 gaattatctg ataaggcgaa agaagaagca gttgccatta tttcttcagg gattagtgac
    14641 tatattgata tgagtggtga aatcaattat ggcgataaag acaaaattgt acgcatgata
    14701 aaagctttta tcaaaacttt tgatgtgaag gcagatctta agtttaatga tacttaccta
    14761 gtaggaaaat taattaatat ccttgggaca gagaaagata cggaaacgtt tatttcctct
    14821 ttgtctatgt tgtttacaga taagcatttt tcaactcagc ttggtggaga ggaactagtg
    14881 gaaatctttt aaccattacg cccagcatta ataaaagtat atcaaaaaag tactcctgat
    14941 gatttttaag attggtttga gaaataatgt gaaaacacta tttttaatgt taattataga
    15001 tagagatgaa cgcgtcatat ggttaaaaga atgaaaaagt caaagataca ctgctatatt
    15061 tcactaagga tatagcagtg tatctttcat gtcgtttcac tggcagtttt ttataaaagg
    15121 aggtgtgcat ttcagttgct tttctttggt agttagttga atcgtttaag aattaacgga
    15181 tgtggcagac aggtgctctg tccaaaaacc agtaaaatct ttgatggttc catctttatt
    15241 tagctgtgcc tgttcaaata ctgttttgtt tttaccgaat ggatcaattg caataattgt
    15301 tccgatcccc gcacgtttgg cagcaagtaa tcctgagtaa gcatcttcga taacaagaca
    15361 atcagccgga gctaagctca gtttgtctgc cgctttaaga aaaatatccg gttgcggttt
    15421 cccagggaaa gagccgtcgt catagacaat cttgtcccag tcaaaccagc gggctaaatc
    15481 gaaaatatca aaataaaaag caacattctc tttgacagta gccgtggcaa tcgttaatgg
    15541 aatctgttgg tcagtcagct ggtcaagagt cgcttcaagc ccttttgtca actgaagctc
    15601 gttttcattt tgcaagcaaa gcatacgata atagctttct ttttcttctg acaatacggc
    15661 gatctcagag gcggtcaaat gctctgaaat gaaatgtttc aaaatctccg tattcgtccg
    15721 accatgaata ttttttaaaa tatcctcgtc tgataaacca tcttttgtat gatcatgtat
    15781 catatgcagc caagcagctt catgcagatg agagtccaaa aacattgttc cgttgaaatc
    15841 aaatataatc cctttcatag ttacgctcct atagtggtat tttcggttga atcagcaatt
    15901 tgcagatcga catattgtgc atagtgctct tgaacctccc gcgagatctg gcgatccgta
    15961 atgagcagat cgaaatcatg caaattataa aacacataaa aatcatctcg attgaatttt
    16021 ttattatcaa cgagtagata tttcttacgg gaattattta gagcgatctg ctgtgcttct
    16081 ccttcttcgg tactgtaagt agagatcgct tcgttgtgaa cgccatttga actgataaat
    16141 gcttttgtaa actttagtct tcttaaattg tcgttggtga tcggtccgac aaatgcgccg
    16201 gtatttttcc ggaaatcacc gccaatcagt agaatttctg gtccatctgc ttgagcaaga
    16261 atatcaaaaa ctggataatt atttgtaatg atccgaattt tcttgttcag taaatgcgtc
    16321 gccaatagtt cgattgttgt acctggtcct aagaaaatcg tttctccctc gtgaatcaag
    16381 gaggctgctg tggcagcaat ttcttttttt tcttgaatct gcagagtggc tttttcagtg
    16441 tgagaaagtt cttgatctaa agtgtaggaa agactttgag cccctccatg gacacgcagc
    16501 agcttgcccg atttttctaa ttcatctaaa tctctgcgaa cggtcatatc agaaacatct
    16561 aattgattga tgatttcatt aacggtaagg attccttttt tattgaccat ttctacgata
    16621 gtaagcaatc tttctttttt caacattgtc ttcacctcta atttaaggat aatctatcat
    16681 ataaacggac aacagtcaat ctaattcgaa caaaagtaaa catttagggt ggtttttatg
    16741 tttgttacaa tagattttat tgctgttttc tggtttttat gattatttgt gtttgttttt
    16801 gttgacaaat gttttggatg cgtttacaat gcaatcagtt agaaagagcg aaaactgatt
    16861 atagatttga ggagagatgt acatgcttaa attaccagaa gattttattt ttggcggagc
    16921 cacagcagcc tatcaggttg aaggagccac taaggaaggt ggcaaaggcg ctgttgcttg
    16981 ggatgacttt ttagaggaac aagggcgatt cagtcccgat ccggcaagtg atttttatca
    17041 tcaatatgca aaggacattg aattgtgtga acgttttggt gtaaatggtc taagattatc
    17101 cattgcttgg agccgcattt ttcctgatgg agctgggaaa ccaaatccag aaggaatcgc
    17161 tttttatcat cgtgtgttcg aagaatgtaa gaaaagaaac gtaacgccgt ttgtgacgtt
    17221 gcatcatttt gataccccta aacgtttgtt tgaccatgga gattttttga atcgagaaac
    17281 aatagaagca tttgtttcct atgccatttt ttgttttcat gaattcaaag aagtcaaggt
    17341 gtggagtacc tttaatgaaa tctatccagt tgcaaccaat caatatttgt taggtgtttt
    17401 cccaccagga atcaaatatg attttacaaa gatcgtcgcc tgtcttcata atatgatggt
    17461 tgctcatgcc cgtgtagtga actatttcaa agaaaacgaa cttccgggtg aaattggtgt
    17521 agttcactca ttagagacga aatatgcggc aacagacgcg ccggaagata agcatgctgc
    17581 ctttttagac gatgcattgt cgatccgttt cttattagat gctacctatt taggctatta
    17641 ttcaactgaa accttgactg ctcttgatga gatatgtgaa gcaaatcagg ccagctatca
    17701 ttttcctgaa gaagatttcg ttgaattgaa aaaagcatcc acgcgtaatg actacttagg
    17761 gatcaatcac taccaatgcc attttgtcaa agcttacgat ggagaaaatg caatccatca
    17821 taacggtacg ggtgaaaaag ggacctctgt ttataaagtg aagggaatcg gagaacgtat
    17881 ttataaagaa ggaattcctc gaactgattg ggactggctg atttatccag aaggtctata
    17941 tgacttgttg ctgcgaatta aaagcgatta cccacattac aacaaaatct atatcactga
    18001 gaacgggatg gggtataaag atcagtttga agatggcatt attatggatc agccgagaat
    18061 cgactatttg agagtctatt tggaatcctt aagcaaggcg ataacagccg gggtaaatgt
    18121 gaaggggtat tttttgtggt cgcttatgga tcttttctca tggacaaatg ggtataacaa
    18181 aaggtatggc ttgttttatg ttgattttga aacccagaag cgttacccaa aagaatcagc
    18241 ttactggtac aagttggtca gtgaaaccaa aacgattatt taataagtga taatggagga
    18301 agaaaagatg aataaagagg aattacaaat gcttggtttt gagatcgttg catattcagg
    18361 cgacgctcgc agtacattat tgaaattatt gaaagaagta agacaaggaa actttgaaca
    18421 tgttgattcg gcgttgaaag aagccgacga aaatttaacc cttgcacata attcgcaaac
    18481 aaaaatttta gcggaagaag catctgggaa agagatggag atgggattca tttttatcca
    18541 tgggcaggat catttaatga ccactttatt gctgagagat ctgattcaag actttattgt
    18601 actgtacaga cagaatcaag gataggagaa gaacgctatg gatggaatca ttaaacaaat
    18661 cgaaaaaggg aaaccatttt ttgaaaaaat ctcacgtaat agttatttag gagccgttcg
    18721 tgacggattt ttaacagcga tgccagctat tttattttca agcattttca ttttgattgc
    18781 tgcggttcct gagatttttg gttaccaatg gcctgaatct gtctccacat ggctatggaa
    18841 agtctataat tattcgatgg gtgttgtagg gttactcgtt tcagcaacca ctgctcgctg
    18901 cttggctgat tcgatgaatc gtcgcttacc gaaaaacaaa gtaatcaaca ccacctctgt
    18961 gatgctggcc tctgtggtaa gtttcctgtt gttaagcgtc tctccgattg aaggtggatt
    19021 ttcaacggaa tatatgggga caaagggact actggcttcc tttgtcgctg catttttaac
    19081 agttaattta tataagtttt gtgtgctgaa agatattacc attaaaatgc ctaaagaagt
    19141 tcctggaacg atttcgcaaa ccttccgaga tatttttcct ttctcttttt cagtatttgc
    19201 ggccgtttta attgatttag gcattcgaca aatcttccaa atctcatttg cagaagcaat
    19261 cattacggtg ctgcagccgc tatttacagc agctgacggg tacttaggaa tcgctattat
    19321 ctggggagcg atggcgctgt tttggtttgt cggtgttcat ggaccgtcga tcgtggagcc
    19381 ggcaattgcg gcaattatct atgccaatgt ggaaaccaat ctgcaattgt tcaattccgg
    19441 tgaacaagct tctaaagtac tgacggtggg tttagggaat tttgtaggaa ctatgggagg
    19501 aactggggca acattggttg ttccttttat cttcctactc tttgctaagt ctaagcagtt
    19561 gaaggcagtt gggaaagctt cctttattcc agtaagtttc gctgtcaacg aaccattgct
    19621 atttgcggca cccatgattt tgaaccctta tttttttatt ccatttttgt taacacctgt
    19681 tgtaaacgtt tgcctgttca agttttttgt cgatgtattg ggcatgaaca gctttatgta
    19741 cgttttgcct tgggcaactc cagcaccgat cggtttggtt ctaggaacgg gcatgggtat
    19801 cttagctttt gttctagcag cggttctaat cgtcgttgac ttcctgatct atctaccatt
    19861 ttgcaaagca tacgatgctg tcttagtaga gaaagaagca caaaaagcag aggtgatcgc
    19921 aaccgaggaa ggtgcttctg ccgatgtacg tgaggaagta cctgtggcag cgagtcaagt
    19981 tatcagcgat gcaaataaag aaatcaatgt gttggtactt tgtgctggcg cagggacaag
    20041 tgcgatgtta gctaatgctt taaaaaaagg tgcatctgaa tcgaaagcac cgatcagtgc
    20101 aatggcgggt gcttatggtt ctcattacga aatgctgcag gattttgata tggtggtctt
    20161 agcaccgcaa gtcaattctt actatgatga tatcaaagaa gacaccgatc gcttaggaat
    20221 caagctggtt gcgacaaaag gagcagaata tatcggatta acgagagatc ctgaaaaagc
    20281 tgttcagttt attctgaacc aatttcaata aaggaggagc cataatgaaa atgggaattt
    20341 ggttgcgtaa agctgtttta tttgcagctg tgttaggggc tttgggggct gtttcaaaaa
    20401 ctgttgaagc atctgccagc gaatttattc gcggagcaga tatttcgatc ctgtcagata
    20461 tggaaaaatc tggtgcaaaa tattatgaag acgatatttc aaaagatgcc ttagagattt
    20521 taaaaaataa tggtgtcaac tatgttcgac tgcgtttgtg gcaggatcct tataatagta
    20581 atggagaaag ttatggagca gggacaaatg atctggaaac gacgattgac cttgcaaaac
    20641 gagcaaaaaa tctgggactt aaggtgctgc tggattttca ctacagtgat ttttgggttg
    20701 atcctgggaa acagaatctt cctaaagcat ggcaaggtct gacctttgaa gaaatgaata
    20761 cggcattgta cgactataca aagaacgttc tgtcggaaat gaagcagctg gacgtttatc
    20821 ctgatatggt tcagatcggc aatgaactga atagcggaat gctctggcct tatggcaagt
    20881 cttggggaga aggcggggga gaatttgatc gattggctgc ttttttgaag tctggtatcc
    20941 aagctgttcg agacactcaa cctaaaacaa ctccagtaat gctccactta gctgatggtg
    21001 gcgatacagg agcatttact tggtggtttg atgaaatcac gagtcgaggt gtgtcatttg
    21061 atttaattgg agtgtcgtat tatccgtatt ggcacggttc aatgaatgaa cttcaaacca
    21121 atatgaatgc gatcagccaa cggtatggta aagaagtgat cgtagttgaa acagcttatg
    21181 ggcatacaac agcgaatgcc gatactatgc caaatgcttt tggtgaagcc gaagcagctg
    21241 cggggggata tgaaccaaca ccgacaggac aagcagagta tttgctggat cttgccgatc
    21301 ggattcaggc agtaccgaat aatcgcgggg cgggcttctt ctattgggaa cctctttggt
    21361 acaacggaaa tgtgagttgg gcaacacaag caggtatgaa ttatctcagt gttcaatcca
    21421 ctatgggaaa cgaatgggac aaccaagcga tgtttgattt tgctggaaac gccttgccaa
    21481 gcttgcgtgc gtttaaacaa gcaggggcgc aaataaatct agttaaaaat gcaagtttcg
    21541 aaagcgatgg accaacgacc agtccttcca attggcaaac ctggtttcaa caaggaaccg
    21601 ctaagggtac gatcaaaacg gaagcgggca ctttttttgg ggactacaaa ctaacttttt
    21661 ggcaggatca agcatacgag gcatcagctt atcaaaatgt tagtggcata agcaaaggaa
    21721 cttacacatt gagtgcctat gtaatgtctg ggggagagtt tgatactaat cagttatata
    21781 tcaaaaatta tggtggagcg gaactaaata ctgcggttgt taaaacaagt gaatggacaa
    21841 aaattacaat caaagacatt ccaattacaa caggtgtttg tgaaattggg gtttatagca
    21901 aggcttcagg aaatgcttgg acgaacgttg attttgtttc attggtgaaa caatagactg
    21961 cggatcgttt cgattcaaga tcggaggttc ccttcagcca catcgttagc gtagaaggca
    22021 ggaatcgaac ctgcacctcg cctttgccaa aaataaccag aaacgatttc cagtcatttt
    22081 taccaaaacg agtaaagcac cagacttcat ctacactttg tattatgcta aagagagttc
    22141 aacgatttcg taagaagcaa tgaaaaaatt gcaaaaagtt gtgcagataa cataaagttt
    22201 gtttaagaaa gggtaacctt agaattccgt cgtgaatatg atttgagcac ttagatggat
    22261 agaaaaaagt tctcggaaaa cagttcgttt ttcgagaact tctttttatg ataagaatga
    22321 aacaaattaa cttatattat agtctctttt ggtagggaac catcttattt ttaatgaaaa
    22381 tcaagcattt tagctattga agaatgttga tttataggga ttccccctcc atattatgtt
    22441 ggctctttat tcccactcca ctgttgctgg tggtttagaa gtgatgtcat acacgatacg
    22501 gttgacgtgg gctacttcgt ttacgatacg tacagagatt ttttgcaaga cttcccatgg
    22561 gatacgggca aagtcagcgg tcattccgtc gattgaagtt acagcacgga taccgactgt
    22621 gtagtcgtaa gtacgtccgt cacccataac accgacagag cggatccctg gaagaacagt
    22681 gaaatattgc cagatatcac ggtcaagtcc agcagctgcg atttcttcac gcaagatagc
    22741 atcagattcg cgtacgattt ctagcttgtc ttcagtgatt tcgccaagaa cacgaatacc
    22801 aagaccagga ccagggaatg gctgacgcca aacgattgaa tcaggcatgc ctaactgagt
    22861 ccctaattca cggacttcgt ctttgaataa tgtgtttaat ggttcgatca attcaaattg
    22921 catatcttct ggcagtccac ctacattatg gtgagatttg atcgtctgtg ctgtttctgt
    22981 accagattcg ataacgtcag tatacaacgt tccttgtgct aggaaagaga cgccttcttc
    23041 accagcaagt tttgttgctt cgtcatcaaa aacatatacg aattcattcc caatgatttt
    23101 acgtttttgt tctgggtcag atacaccttt caacttgtct aagaagcgat ctcttgcatt
    23161 gactttgatg atgttcaagc cgaattttcc gcctagactt tccattactt gttccgcttc
    23221 gcctttgcgt agcagaccgt ggtcaacaaa gatagatgtc aattggtcac cgatcgcttt
    23281 ttgtaaaaga accccaacga cactagaatc aacgccacct gaaagaccaa gcaagacttt
    23341 tttgtcacca acttgttcac ggattttttc tacttgcata tcgataaagt tatccattgt
    23401 ccagttacct tcacagtgac aaacatcaaa ggcaaagtgg cgcagcaatt cgattccgta
    23461 ttcggaatga cgtacttctg catggaattg gataccataa aaattacgtg ttgtgtcttg
    23521 gatagaagca atcggacaat ctttgcttgt tccgactgtt tcaaagcctt caggaacttt
    23581 agttaccaag tcaccatggc tcatccatac tgtttgttgt tttggtgttt ctttaaacaa
    23641 gacagcttga tcgcttgtta cttctaacaa ggctttccca tattcgcggt ttttagcagg
    23701 ctctacggaa ccgccaagtt tgtacgtgat caattgcata ccatagcaaa tccctaatac
    23761 aggaatacct aaattgaaga tctcaggatc gatcccaaat gcattctcat catatacact
    23821 gtttggtccg ccagaaagaa tgattccctt tggattcatc gcttttactt cttctgcagt
    23881 aatgcggtgg ctcaataatt cggaaaagac tccaagatca cgaatacgtc ttgtgatcaa
    23941 ttggttatac tgactaccgt agtctaatac gataatcttt tcaacgttcg tcatatcggc
    24001 aacgtttgtc aaatttatta cccctatccc tttaaatttt atctcaaaat agtcaaacta
    24061 ttttaaaatg ctaatatttt cgcatgaaaa tcgaatcgat gatatgattt tcagttttat
    24121 ggagaattat atcggctctt cctcgtgtag gcaagatata ttcctgtaaa tttttcaaat
    24181 tcacattttt ccatacatct tttgccattt taaaggcttc ttcacgatct ccgatagcaa
    24241 aacgataata ataattctct ggattttgga aagccgtatc cagtaacgca ccaaaacgat
    24301 ccaaatacca tttttcgatc agcacgggat cggcatcgac atagacagaa aaatcaaaaa
    24361 agtcgctgac gtagatttgc tgattcgcag gtaattgaag cgtattgatc ccctcaacga
    24421 tcaagatatc aggctgctgg atcaattcgt acttgtctgg aatgatatca tacacatcat
    24481 gtgagtaaac aggtactttt atctcttcct gaccagattt tacacggttc aagaaatcga
    24541 tcagcatctc catatcataa ctttcaggaa atcctttacg gtccatgatt ccacgctctt
    24601 ttaatatacg atttggataa agaaatccgt cagtcgtgat cagctgaacg tttcttcgtt
    24661 tgaaggtacg agacaaaatc gtctgcagca gtctggctgt tgtacttttt ccaacggcta
    24721 cacttccggc gatcccgata ataaaaggcg gtacttctac gtatttatga agaaataaac
    24781 ctttactcaa gaacaaagat tcaaattctt tcatataaag ataaatcaga tgagcaagag
    24841 gtacatagat atctcgaaca tcctgcatgg aaatgcggtc attcaaactt ttgatattat
    24901 ctagttcatc ttgtgtcaaa ggtgcttgcc cattacgata aaattctcgc cattcttctc
    24961 ttgccacacg gtagtagttc attggatcat tcatattagc ctcctgcgtt ctcccatcaa
    25021 tggaactatt ttaacacaaa ataaacgcaa accccaccac ttaagagaga ttgccgatct
    25081 ttttgtataa tctttataat agaaagaaac ggagtcttat tcttgacttg cgcacggata
    25141 cataaaagga tagactgttg tcatgaaaga aatgagaagg atggaagaca tgacaaatca
    25201 ttactattct gaacgcccag atacggcgca cgattttgaa caatgggctt ttgagttaaa
    25261 aggcagaacc tttcaatttg taacagattc tggtgtattt tcacgtgaaa cagtggatta
    25321 tggttcacgt gtcctgattg atgctttcga ttgggaagag ttacctgatg aaggaaagat
    25381 cttagatgtg ggatgcgggt atggaccgat tgggttagct ttggcatttg cgacacagcg
    25441 gtttgttgaa atggtcgaca ttaatgaacg agcggtaagt ctagcgcaag gaaacgcaaa
    25501 gcgtaaccaa atcgaacatg ttgatatcca tcaatcgaat atctatgaag cagttcatga
    25561 agaaacctat gcagctatcg taagcaatcc gccgatccgt gctggaaaaa aagttgtaca
    25621 tgaaattttg acaggcgcat atcctcggtt gaagaagggc ggtacactga caattgtgat
    25681 ccagaagaaa caaggagcgc cgagtgcgca aaagaaaatg gaagaaacat ttggtaatgc
    25741 agaaatcgtc acaaaagata aaggatatta tatcatcaaa agtgtgaaag aataactagc
    25801 tgaaaaatag tggagcgacg aaagagtgga actgggcgtg catgtacggg tacgtatcag
    25861 ttcttttttt gttgagaagt ttttaaaaac aaagaactat tttttcttca aaaagaaata
    25921 gtaggaacag agtcgttgtt ttttacgata aaataaataa gatacagaac ttgtatagaa
    25981 ggctgccaag tcggtagata aaggaggttt ttatcaaaaa acatactttc cttttttctc
    26041 tattcttttc ttgggggttt tggtacactg atagggaatt tagatagaag ggagccaata
    26101 ggatgaagct gaccatcaga gatatcgcag aaatggcagg cgtatcagta acaactgtct
    26161 cacagatttt gaataacaaa ggaagcagat ttagtgataa gacaagaaaa aaagtgttgt
    26221 cgatcgtgaa tgaacatcat tataagcccg attatttcgc ttcaaatgtg atcaatcgac
    26281 attcaaagac catcggaatg atcgtccctg atgtcactga tttcttcttc tccaaactga
    26341 tcgaaggtgt agagagctat ttgaatcctt tgggctatgt gatcatgtta tgcaattctc
    26401 gtcatagcca agaaaatgag atcaagtatt tacaagagct ttcccaccgc tcagtggacg
    26461 gaatcttgct ggccacacca aatattttac ctgagaaata tgcattagac agcggttttt
    26521 atcaaaaaat gccaatcatt ttaatcgatc gcggattgaa tcgtcgggat aacggacggc
    26581 ttatcgtaaa ggaatatgag ggcgcctatc aagctgtttc gctgtttatt gaaaatggcc
    26641 atacgaagat cggcatgctg aaggaaacca ctggatacta tcaattagaa gaacgtttca
    26701 acggatatcg tcatgcgctg aaagatcatg gcctgccttt taatgggaaa tttgttgaac
    26761 atggagagtt gactgtccaa ggtggatata ctgcatcaaa aaaattactc aaacataaag
    26821 atatcacggc tattttttgc gggaatgatg ccatggcgat cggatgctat caggcgatcg
    26881 atgaattggg caaaaaaatc ccagaagata tctcagtcat aggattcgat ggattaaagc
    26941 tgtcagaata catgattccg caattgacga cagtgcagca gccaagtttt gatattggat
    27001 tttatgctgc acgtttcctg atcgatacga tcgaatttcc tcaaagaaaa gttccgaaca
    27061 aagtgttcga aacaaaatta attattcgtg agagcgtaaa agtattgaca aagggctaac
    27121 tcggcggtat attgcttatg taagcattta caaaggctag ttagtgcttt ttttattttt
    27181 agtaaaccag tttactaaag tggtttacct ttcctaaaaa taatgtataa taccgaatga
    27241 agacaaggag gatcaggcaa tgcgaatggt ggatctgatt gaaaaaaaga gggatggaaa
    27301 cgagctgtcg aaagaggaaa tcgagtacat cgtcacgaac tatacgaatg gaaagattcc
    27361 agattatcaa gtcagtgcat tattgatggc aattttttat caagacatga caaatgaaga
    27421 aatcacgaac ttaacattgg cgattgctaa ttctggtgat gtcatcgatt tgagttctct
    27481 tgaaggaata aaggtagata agcattcgac aggtggcgtt ggtgacacga ccacattgat
    27541 tttagccccc ctagtagcta gtgtcggagt gacagtggct aaaatgtctg gacgcggtct
    27601 aggttacaca ggtggtacac tagacaagct agaagcaatt cccggatttc agatcgagct
    27661 ttcggatgaa gaatttgtac gcattgttaa tgaaagtaaa gtagcggtaa ttggtcaatc
    27721 aggaaacttg gcaccggcgg acaaaaaatt gtatgccttg cgtgacgtca cagcgaccgt
    27781 tgattctctt ccgctgattg ccagttcgat tatgagtaaa aaaatcgcgg caggagcaga
    27841 tgcaatcgtt ttggatgtga ccactggaga cggtgctttc atgaagaaca tcgaagatgc
    27901 aagacgtctg gcaaagacca tgacgagcat tgggaaactg gctaaccgag aaacagtggc
    27961 ggttatctca gatatgtcag aacctcttgg cgaagctatc ggaaatagtc tagaagttgt
    28021 cgaggcaatc gaaacattac aaggaaatgg tccagaagat ctagtagaaa tgtgctacgc
    28081 cttaggaagc caaatggttg ttcttgctgg caaagctaag acaaccgatg aagcaagaac
    28141 gttgcttcaa gaagctctgg aatcaggtaa agcgttagca aaattcaaag aaatgatcca
    28201 aaatcaaggg ggagacccag cgatcgtgga acatccagaa cgaattttga ctgcacgcta
    28261 cacaatggag cttcctgcta aacaaagcgg agttgtgtca aaaatcgtgg caaatgaatt
    28321 aggaattgct gcaatgatgc taggtgctgg gcgtaaaacc aaagaagaag atattgatca
    28381 cgctgttgga ttgaaactgc ataaaaaaat tggtgacact gtgacaaaag gtgagtcact
    28441 attgacgatc tatagtaacg acgaagaaat cacttctgtc attgaattat tatataaaaa
    28501 tattgaaatt ggtgaatcgg caatgaagcc aacgttgatt catgacatca tcacagaata
    28561 aaggaaaaaa gcggacttta ccgttttaaa gaaaagggga aaagaaatgg aactaaaccg
    28621 aatgatcgac catactattt tgaaagcaga cgcatctaaa gaagctgtga tgcaaattat
    28681 cgaagaagca aaaaaatacc atttttattc tgtctgcatc aatccagcat gggttgcgct
    28741 agcgaaagaa caattacaag gtgagccagt agccgtatgt acagtaatcg ggtttcctct
    28801 aggagcaaac acacccgaga caaaagcatt tgaaacaaca gatgccatca ataacggtgc
    28861 agatgaagtc gatatggtca tcaatatcgg tgctttgaaa tcaaaggatg atcaacaagt
    28921 ccaaaaagat atcgaagcag ttgttgaagc agcaaaagat cgtgcgcttg tcaaagttat
    28981 tattgaaaca tcgttattag atagagaaga aatcatccga gcttgcgaaa tagcaaaagc
    29041 tgcaggcgct gattttgtca aaacatcaac tggtttctca acaggcggag caaaggtaga
    29101 ggatgtccgt ttgatgcgtg aaactgtagg accagaaatg ggtgtcaaag cttccggcgg
    29161 tatccataac gaagaagaag caatggcaat gatcgaagct ggtgctacaa gaatcggaac
    29221 aagcgcagga gtagcaatcg tatctggttc aactggtgaa ggctattaat tttttcaaag
    29281 gagaagctca tggcagaact caaacaagaa tggatcaaca cagctattga agcgttagat
    29341 aaagcctatg ttccttattc ccattttccg gtaggcgctt gtctcgtaac ggaatcaggc
    29401 aagatttatc aaggcatcaa cattgagaat gcatcatttg gattaacgaa ttgtgccgag
    29461 cgcacagctt ttttcaaagc agtatctgaa ggagaaaaaa catttacgca tctagtcgta
    29521 gcggggcaca cccccgatcc tatctctcct tgtggtgcat gtcgacaagt aatggcagaa
    29581 ttctgttccc ctgatatgcc ggttacgcta gtaggagaca atggtgtgac gaaggcaacg
    29641 accgttcgtg cactgctgcc ttatgcattt actgaaaaag atctataact catgttcatt
    29701 cagtcagctg actgttgaaa aataaaacaa ttattttagg aggctttaca gaaatgaaaa
    29761 aagcaaaatt atttggttta ggtgctgtcg cactagcagc agggttattt ttaggtgcat
    29821 gcggcaacaa cggctctact gattcatccg gtggcaaaag ctcatcagac acaacaactg
    29881 cagcattgat cacagacaca ggtggtgtag acgaccgttc attcaaccag tcagcttggg
    29941 aaggactaga aaaatggggg aaagatcaag gactttcacg aggaaatgat ggcttccaat
    30001 atttccaatc ttcaaatgaa tcagattaca tcccaaatat tgaccaagca ttgaatgctg
    30061 gattcaaaac gatttttggt attggttata aactaaaacc agcgatccaa gaacaagcaa
    30121 caaacaatac aggtacgaac tttgttatta tcgatgatgt catcgatgga ttagataacg
    30181 ttgtatctgc aactttcaaa gacaacgaag cttcttatct tgcaggtgtt gcagcagctt
    30241 atacgactga aacaaacgta gtcggcttta tcggcggtgt aaaaggtgaa gtaatcgatc
    30301 gttttgatgc tggattcaaa gccggtgttg atgcaggtgc gaaagaatta ggaaaagaaa
    30361 tcaaagtatt gaatcaatat gctggtgact tctctgctcc agataaagga cgttcaattg
    30421 ctcaaggtat gtatgcacaa aacgcagata tcatcttcca tgcttcaggc ggtacaggta
    30481 acggtgtatt ccaagaagca aaatcattga acgaatcagg cgacaaaaaa gtttgggtta
    30541 tcggtgttga ccgcgaccaa tcagacgaag gcgaatacac attaaacggc gaaaagaaaa
    30601 acttcacatt gacatctaca ctgaaagcag ttggaacagt agtagaagat ttggcacaaa
    30661 aatcagcgga cggtaaattc cctggcggcg aacacactgt ttatggattg aaagaagacg
    30721 gtgttggtct aacagaagga caactttctg acgaagcgaa aaaagcagtt gatgaagcaa
    30781 aagaaaaaat catttcaggt gacgtaaaag ttccagaaac tcctgaagaa aactaaaacc
    30841 atttctatag ccttgttaga cacatgtttg acaaggctat ggtttgatta gaacaagaat
    30901 tgttcattta tccaagctgc cttgtgacag tttggataag ggaacaactc cctgaagtaa
    30961 tgtttgtttc aaaagaagaa cgctcactaa gcgtgaatct tagtcaatcg ttgccctaga
    31021 tagaaatcgt taggatgtga aaaaaaggtg gttcaagaaa atattgtcat agaaatgcag
    31081 aatattacca aagaatttgg aacattcaag gcaaatgaca acatcaattt acaagtaaag
    31141 gcaggagaaa ttcatgcgtt gcttggagaa aacggtgctg gcaaatctac attgatgaac
    31201 gtgctttccg gattattaga gccgacatca gggaaaattt tgatgcgtgg gaaagaagta
    31261 aagatcacaa gtccgaccaa agccaaccaa ttagggattg ggatggtcca tcagcacttt
    31321 atgcttgttg atgcctttac tgtaacagaa aacatcgtgt tgggaagcga gcctagtcgc
    31381 gcagggatgc ttgaccataa aaaagcacga aaagagatcc aaaaagtttc tgaacagtat
    31441 ggattgtcag tcaacccaga tgcttacgtt cgtgatattt cagttggaat ggaacaacgg
    31501 gtagaaattt taaaaacact ttaccgagga gcagatgtac tgatttttga tgagccgaca
    31561 gctgtattga cccctcaaga aattgatgaa ttaatcgtga tcatgaagga attagtcaaa
    31621 gaaggcaagt cgatcatttt gattacgcat aagttagatg aaatcaaagc agtagctgac
    31681 cgctgtacag ttatccgccg tggaaaagga atcggtacag tcaacgttaa agacgtaacc
    31741 tcacaacaat tagccgatat gatggttgga agaacggttt cattcaaaac gatgaaaaaa
    31801 gaagcgaagc ctcaagaagt cgttttgtct attgaaaatc tagtggtgaa agaaaatcgt
    31861 ggattagaag ccgtgaaaaa cttgaactta gaggttcgtg ctggcgaagt acttggtatc
    31921 gctggaatcg atggaaacgg gcagtcggag ttgatccaag ctttgactgg tttgcgaaag
    31981 gcagaaagcg gacatatcaa gctaaaaggg gaagacatca ctaataaaaa accccgaaaa
    32041 atcactgaac atggtgtagg acacgtgcca gaagaccgtc ataaatacgg gttagtccta
    32101 gatatgacat tatctgaaaa tatcgcacta caaacctatc atcaaaaacc ttacagtaaa
    32161 aacggcatgc tgaattattc agtaatgaat gaacatgcca gagaattgat cgaagaatat
    32221 gatgttcgaa caacgaatga acttgttccc gcaaaagctt tatcaggcgg aaatcagcaa
    32281 aaagcaatta tcgctcgtga agtcgaccga gatcctgatc tgttgattgt tgcaaatcca
    32341 actcgtggac tggatgtagg tgcgatcgaa tttattcata aacgtctgat cgaacaaagg
    32401 gacaaataca aagcagtgtt actgatcagt ttcgaattag aagaaatttt aaatgtttcg
    32461 gatcgtattg ctgttatcca tgaaggagaa attgtcggta tcgttgatcc gaaagaaaca
    32521 tctgaaaatg aattaggtct attgatggcg ggctatacct tagaagaagc acgaaaagag
    32581 ttagaaaagg gggctggcgc acatgaatga tcgcagcgaa aaattccgta atttattagt
    32641 gcctgtactt tcagttgttt tagggttgat cttaggcgcg atattgatgg ctgcttttgg
    32701 ttttcagccc atccaaggtt attcttctat gctagatgca gcccttggtt cgcaaagagg
    32761 gataggtgaa acgttaaggc aagcaacgcc gttgattttt acagcattag gtttttctgt
    32821 agctaactca gctgggtttt tcaatattgg gctttctgga caagcacttt gcgggtggat
    32881 cgtcagtgtc tgggtggcac ttgcgtttcc agatctgcca aaagttgttt tgcttccgtt
    32941 atgcgtgatc ttaggtgcct tagctggtgc gatggcagcg gctgttccag gtttacttcg
    33001 agcatttttt ggaacaagtg aagtgatcgt aacaatcatg atgaactata tcttattata
    33061 cgtaagcaca tttgctttac atgaagtgat gcctgaaagc tatcgctcaa gtttggactc
    33121 ttccaatatg atcagtcaaa atgcctcact gcggttacca tggttaacac aagcttttgg
    33181 cggctctcgc gtaaactcag gattattttt agcaatcatc gcgcttattt tcgtttggct
    33241 gctgatgaag aaaacgactt taggatttga aatccgttct gttggattga atccttttgc
    33301 ttctgagtat gcaggaatga gtagtaaacg tacgatcgtt ttgtcgatgg tcatttctgg
    33361 cgctttggca gggcttggcg gtgtggttga aggattagga acgtatcaaa acttctttgt
    33421 tcaaacgact tcgctatcta ttggatttga cggaatggct gtttccttgc ttggttctgg
    33481 atcagcaatc ggtattcttt tatcagcgat cttgttcagt attttgaaga tcggtggact
    33541 tggcatgcag acaggagcag gtgttccgtt tgagatcgtc aatgtatcga ttgctttgat
    33601 tatcttcttt gtcgggatca acttcctgat tcgtttcgtc atggctaaag tcttccaagg
    33661 gaaaaaacaa gaagagatcg ttgcgacaat agaatcgaaa ccaacgaatc aaaaccatga
    33721 agggggcgaa ctataatgtc gactatcgaa ttaattgcct tgatccttac ttctacactg
    33781 gtttattcaa caccgctaat tctaacgtca ctaggcggaa ctttttctga acgaagcggg
    33841 atcgtaaacg tagggctaga gggaatcatg gtcatgggtg cttttagttc catcgttttc
    33901 aacttgacga tgagtccatc acttggttct atgacaccat ggatcgctat tttagtgggt
    33961 ggcgtcgtag gtatcctatt ttctctgatt cacgcagtag caacagtcag tttgcgtgct
    34021 gaccatatta tcagcgggac agtaattaat ctgatggcac ctgctttagg tgttttcttg
    34081 atcaaagcat ggtatggtaa aggtcaaact gataacatca cgcagaatct ggggtatttt
    34141 tctttcccag gattagcaga tattccggtc attggaccaa ttttctttaa aaatacattc
    34201 ttacctgctt attgtgctat tttgattgct gtcctagctt gggtgatcat cttcaagacg
    34261 aaattcggct tgcgcctccg ttcagttggt gaaaatcctc aagctgccga cacattaggt
    34321 atcaatgtat atgctatgcg ttattcaggc gtactgattt ctggcttgtt aggcggtatg
    34381 ggcggtgctg tttttgctca gtcgatttcc ggtaactttt cagctggtac gatcgttgga
    34441 caagggttca tctccatggc tgctatgatc tttggtaagt ggaatccttt aggggcaatg
    34501 ggtgcctcat tgttctttgg ttttgctcaa agcttgagta tcattggcgc acaattacca
    34561 gttatttctt cgattccgcc agtattgctg caaattgctc catatttgct gacaatcatt
    34621 gtgctggttg ttttcttagg gaaagcttct ggtccaaaag caaacgggaa gaactatatc
    34681 aaatcaaaat aatcttttag cgaataaaaa gggtgggtta cgggaagtgt ttttcgtctc
    34741 gccctttttg ttttaaaggc aataaaaata aaaagaaaga aggaataatc atgtttaaac
    34801 gcgtacatct gatcgtcatg gattcagtag gaattggaga agcaccagat gccgataagt
    34861 tcggtgatgt tggttctgat acattaggac acattgcgaa agaagcagga ttgaacgttc
    34921 cacatttaga gcagcttggt ttaggaacga tccgtcctct tgaaggtgtg gaatcagtga
    34981 aagatcatca aggctatgcg acgaaattag aagaagtttc tgtagggaaa gatacgatga
    35041 caggccactg ggaaatcatg ggattgaata tcaaaactcc atttcgtgtg tttcctaatg
    35101 gattccctga tgatctgatc aaacaaatcg aagaattttc tggccgtaaa gtcgtatgta
    35161 acaaacctta tagcggaaca gctgttattg acgattacgg tgaacaccaa atgaaaacag
    35221 gcgatttaat tgtatatact tctgccgatc ctgtccttca gatcgcggca catgaagaaa
    35281 tcattccttt agaagaatta tatcggattt gccaattcgt tcgtgatata acaaaagatg
    35341 atccgtatat gattggccga atcattgcac gtccgtacgt gggtgaacca ggagacttca
    35401 cacgaacaag caatcgccat gattatgcgt tgaatccatt cggacacaca gtccttgatt
    35461 ctttgaaaga agcaggaaag gacgtgattg ctgttggaaa gatcaacgat attttcaacg
    35521 gacaaggaat cactgaatct gtccgcacga aaagcaatat ggatggcgtt gaccagctgc
    35581 tgaaagttat gaaaaacgat ttttcaggaa tcagctttac caatttagta gattttgatg
    35641 cattatacgg tcatcgtcgg gatgtagtcg gctatgcgca tgcgattgaa gaatttgact
    35701 tacgaattcc agaattgctt gaagcgatgg aagaagacga cttgctaatg attacagccg
    35761 atcacggaaa cgatccgacg tttactggta ccgatcatac gcgagaatat gtaccgttat
    35821 tggtttacag taaaaaaatg aaagaacaag gggcattgcc tcaaggatat tattcagata
    35881 tttcagcaac gattgctgag aactttagtg tttcttcgac tgaaaatggc gaaagcttct
    35941 tgaaattatt aaaataatct ttttaaatag gagaaagcaa atgaccaagt taagcgagat
    36001 gttacaagaa acgacccagt ttatccttga taaaggagta aaagaaattg attttggttt
    36061 gattctaggt tcaggattag gtgaattagc agatgaaatc gaagatgctg taatgatttc
    36121 ttatgatgag atcccgttct ttcctgtttc gacagtagtt gggcatgcag gaaagctagt
    36181 ttatgggtct ctggcaggca agaaagtgtt agccatgcaa gggagattcc actactatga
    36241 aggtcattcc atgcaaacag tgacctatcc agtacgtgtg atggccggac taggggccca
    36301 ttcagtcatt gtgactaatg catgtggtgg tgtcaacgaa tcatttgtac caggagattt
    36361 gatgctgatt accgatcata tcaattttac tggtgaaaat cctttgatcg gtccgaatga
    36421 agatgcaatg ggccctagat ttccagatat gagtcaagct tatacgcctg actatcaagc
    36481 aacagcaaaa gcagcagcag aaaaactagg tttggatctt aaagaaggcg tatatatggg
    36541 ctattctgga ccaacttatg aaacgcctgc ggagatccga atgtctcgga caataggagc
    36601 cgatgcagta gggatgtcga ctgttccaga agtcatcgta gcagctcaca gcggattaaa
    36661 agtgttagga atctcttgta ttaccaactt agcagcaggt atgcaagcga atctgagcca
    36721 tgaagaagtt gtagaaacaa ctcagagagt caaacaatct tttaaagcat tggttaaaga
    36781 aacattgaca ttattgtaat aggaggaaca ataaaatgag tgtgcatatt gaagcgaaag
    36841 aaggcgagat cgccgataag attttacttc cgggagatcc tttgcgagct aaatatattg
    36901 cggagacttt tttggaagat ccagtttgtt acaatcaggt acgcggtatg ttaggcttta
    36961 ccggcaaata taaaggagaa cgtatttctg ttcaaggaac aggaatggga atgccatcag
    37021 ccaccatcta tgcccatgaa ttgatccagt cgtatggtgt aaagaaattg attcgagtag
    37081 gtacatgcgg tgcattgtca aaagacgtcc atgttcgtga tttagtacta gcacaaggtg
    37141 cagcgaccag ttcttcgatg atcgaaaaaa atttccaagc ctttcatttt cctccaatca
    37201 gtgatttcaa tctattactg aaagcatatg agatagctaa agaaaagggc tatacggttc
    37261 atgtaggaaa tgttctttcg gaagattctt tctacaaaga tgatttgaca gagacgttcc
    37321 aattagctga acttggcgtt ttaggagtgg aaatggaagc agcggctctt tattacttag
    37381 gcgcgaaata ccatgtgcag acattaagtt tgatgaccgt tagcgaccat ttgatcaccg
    37441 gtgaagaaac aacagctgca gaacgtcaat ctacgttcaa tgaaatgatc gaagtaggat
    37501 tggaaacagc gatagcagaa taagaaggaa atgaaaaagc tgccctgcat taagtaataa
    37561 gaacatccaa gcaaaaatag ctcctcatgt ttttgacttg gctggactta ttattgcaaa
    37621 tgtaagcttt tgaacaccgt ttaccaagag gttgtgaatc tgccgtttaa ctctgagtca
    37681 caaggaacaa tttcaaaaaa cagcttttca tgtttgatga atattgtgac ttgtgaccga
    37741 gaagttggca ggagaaaacc gtttatacga aaaaagggac tgtgacaaat cgtgtcacag
    37801 tccctttttt atagtgtttt ttataggtag tattttttag caactgttaa gtcatcattt
    37861 aattcataaa caagtggttg acctgttgga atttcaagat ccatgatgtc ttcgtcagag
    37921 ataccttcga tatgtttagc tagggcgcgt aatgagttac catgtgcagc tactaaaaca
    37981 gttttgttgt ctagtaatgc tggagcaatt tcatcttgcc agaatggcaa agcgcgttct
    38041 aatgtcactt tcaagttttc tccaccagga atatcgcgtt tgtctaacat tgcgtaacga
    38101 cggtcatttg ctgcagaacc ttcgtcagtt tcttccatta atggaggaag agtatcgtaa
    38161 gaacgacgcc agatgtgcac ttgttcgtcg ccgtattttt cagctgtttc ttttttgttc
    38221 aaaccttgta atttaccata gtgacgttcg tttaagcgcc atgatttgat ttgtggtacc
    38281 caaagttgat ctgaatattc taagatcaag ttacatgttt tgattgcacg agttaaaaca
    38341 gaagtgtaag caacatcaaa ttcgattcca gcttctttga ttttgcgtcc gccttctttt
    38401 gcttcttcga ttccttctgg tgctagattt acatcagccc aaccagtaaa ttggttcaat
    38461 gcattccatt cactaagacc gtgacgagaa aaaactaatt ttggcatgtt tagctctcct
    38521 tttaagatag gtttatattt ctgaaatttt cagttctgtt ttattgtaca attttttgga
    38581 agagatttcc atcgaaaaat tagataagat tctatgagaa aacaagtaga gaatataaaa
    38641 aaacgaacag tgcccacgca actgttcgtt tttaggtatt agatgcataa ttgctcgatt
    38701 tctttttcag gtaaattgat atatttataa catgttccaa ctgaaacacc gcattttgaa
    38761 gaaataaatt ggatcgtttc ttttttttca taatagagac gtcggatttt tttgatcgtt
    38821 tttgcatcga tttttggtct tccgccgatt tttccttttt tacgagcttc atctaatcca
    38881 actaatgtac gttctttgat caatgcgcac tccatgtttg ctaggttttc cattaattgg
    38941 aaatagattt ttcccatttc gcgcgtatcg attccttcat caagactaat caagtgcagc
    39001 ccgcgatctt tgaataattg cgtgagttct gttaattgcc gcgtagattt gcctaatcga
    39061 tgaagttggc aaatgactag tgcatcgcct tgttgcatgt cagcgatcac tgactccaaa
    39121 tgaacagcag tagaatcatt ttgttccact tcatatgtct catggaaaat ttcttgacaa
    39181 ccaaagtcag ataattgatc aacctgagtt gttaaatcaa cgtcatttat ggttgtgcgt
    39241 gcataaccaa taattttcat ggtgattcct ttctagcagt gattttctaa ctggatataa
    39301 cagtaaaaat gtagcataaa gtacgtcaaa aagatagttt tttcgcaaat tttccgctgt
    39361 ctttttttat tggatgatca agcagttttt ctttatttac gacggattgc gtcaagaatc
    39421 tcaacgcctt tttctgagcc gacaactact ttagaaacca tgtttaggaa aagcccatgt
    39481 tctactaccc caacaagttc atctaaatag gtagctaagc tttctggctg ttcgatgact
    39541 tctagatgca gatcaatgat gtaatgacca ccatctgtgg ttaagacttc tccgttttcg
    39601 tctgtacgca agacgggttg gaatcttttt tcttcaaaaa tatgaagtag ctgttgggag
    39661 ccataaggga tcacttcaac tgggagtggg aacttcccaa gtttatcgac taatttagaa
    39721 gaatcaacga tccaaatcgt ttcttttgag tacgtagcga ctattttctc gaaaagcaaa
    39781 gcagcgccgc cgcctttgat cccttgaaaa tcagcactga tttcatcagc accgtctatt
    39841 gtcaaatcga ctacggggac ttcatcaata ctctttaacg gtattcctaa tttttccgct
    39901 tgttcttttg tcgcatttga agtagtaact cctgtgatac gtaaaccttc ttcacgcata
    39961 cggcgaccaa tctcttctac catataatag gcggttgaac cggtcccgag acctacgatc
    40021 atcccgtcct ttacgaattt cgcggcttca atgccagcta attgttttaa attcatcttt
    40081 gcgtccacct ttttttagtt tgagcatcgt gctttcctca ctattttagc gtgatttacg
    40141 gtaaaaagat accattcttt tttattccaa taaagctttt tcaaaaaaaa ttgcatctct
    40201 tgttgacatg ttttttcatt cgtgatattc taacaaaggt gctttatcta caggtttctg
    40261 tgaagaaacg tgctgactgt ttatcaaagc atatttgata aggatgcaga cattgcattt
    40321 attttttatc acaaaaaaag aaccacctgg atgtgtggaa ctagacgcaa atcgtgggaa
    40381 ggaggaaaca aggaatgcct acaattaacc aattagtacg taaacctcgt aaatcaaagg
    40441 tggaaaaatc taattcacct gctttgaaca aaggatataa cagctttaag aaaactcaaa
    40501 ctaacgtaaa ctcacctcaa aaacgtgggg tagcaactcg tgtgggtaca atgacaccta
    40561 aaaaaccgaa ctcagcttta cgtaaatatg cacgtgttcg tttgtcaaac ttaattgaag
    40621 ttactgctta tatcccaggg attggtcata acttacaaga acacagtgtt gtattattac
    40681 gcggtggtcg tgtaaaagac ttaccagggg tacgttacca tatcgttcgc ggtgctttag
    40741 atactgctgg tgttaacgac cgtaaacaaa gccgttctaa atacggaact aaaaaaccta
    40801 aagcttaatt ttaattatta aacaaatgaa acttgcttct actatataga agtaattact
    40861 atgaacaata tttcggaagg aggagttacg gatgccacgt aaaggtcctg ttgcaaaacg
    40921 tgatgtttta ccagatccta tttataactc aaaattagta actcgcttga tcaaccgtgt
    40981 aatggttgac ggaaaacgcg ggattgcagc taacattatc tataatgcct ttgacttgat
    41041 caaagaatct acaggtaacg atccattaga agtgtttgaa caagcaatga aaaacgttca
    41101 acctgttctt gaagttaaag cacgtcgtgt tgggggttca aactaccaag taccagttga
    41161 agttcgccct gaacgccgcg ttactctagg tcttcgttgg gtagtaaact acgctcgctt
    41221 gcgcggtgaa cacacaatgg aagaacgctt agcaaaagaa atcatggatg ctgcaaacaa
    41281 cacaggtgct tctgttaaaa aacgtgaaga cactcataaa atggctgatg ccaaccgtgc
    41341 gtttgctcac tatcgctggt aagattctct ctgtttggtc ggcttttata agtcgacctc
    41401 agatagtgtc cttattttta gcaactagat agtaaagaga ggagaaacaa ggagaatgac
    41461 cagagaattt tctttacaaa acactcgtaa tatcggtatc atggcccaca tcgatgctgg
    41521 taaaacgact gctactgaac gtatcttgta ctatactggt aaaatccata aaattggtga
    41581 aactcatgaa ggagcttcac aaatggactg gatggaacaa gaacaagaac gtggtattac
    41641 gatcacttct gctgctacta cagcacaatg gaagggtcac cgaatcaaca tcatcgacac
    41701 accaggacac gtagacttca cagttgaagt tgaacgttca ttgcgtgtac ttgatggtgc
    41761 tgtaactgtt cttgatgcac aatcaggtgt tgaacctcaa actgaaacag tttggcgtca
    41821 agcaacaact tatggtgtac ctcgtatcgt atttgcaaac aaaatggaca agatcggtgc
    41881 tgacttctta tattcagtat caactttaca tgaccgtttg caagcaaacg ctcacccaat
    41941 ccaattacca attggtgcgg aagacgactt cacaggaatt atcgaccttg taacaatgaa
    42001 ggctgaaatg tatacaaacg atcttggaac agagatcgaa gaaacagaaa ttcctgaaga
    42061 ataccgcgaa ttagctgaag aatggcgcga aaaattggtt gaagctgtag ctgaaactga
    42121 tgaagaactt actttgaaat acttagaagg tgaagaaatc actgaagctg agttaaaaga
    42181 aggtatccgc cgcgcaacag ttaacgtaga attctaccca gtactatgtg gttcagcatt
    42241 taagaacaaa ggggttcaat tactattgga cgctgttctt gattacttgc catcaccgtt
    42301 agatatccca gctatcaaag ggattgaccc taaaactgat gaagaagtag aacgtcctgc
    42361 agacgacagc gctcctttct cagctttagc atttaaagtt atgactgacc cattcgtagg
    42421 tcgtttaact ttcttccgtg tgtactctgg tgttttacaa tcaggttcat acgtacaaaa
    42481 cgcaacaaaa ggcaaacgtg aacgtgttgg tcgtatccta cagatgcatg ccaactctcg
    42541 ttcagaaatc tctgaagttt acgctggaga tatcgctgct gctgttggtt tgaaagacac
    42601 aactactggg gacacactat gtgatgaaaa gagtctagtt attcttgaat ccatggaatt
    42661 cccagaacca gttatccaag tcgctattga acctaaatca aaagctgacc aagataaaat
    42721 gggtgtggct ttacaaaaac tatctgaaga agatcctact ttccgtgctg aaacaaacgt
    42781 ggaaacaggc gaaacaatca tcgctggtat gggtgaactt cacttagata tcatcgttga
    42841 ccgtatgcgt cgtgaattca aagttgaagc taacgtaggt gcgcctcaag tatcttaccg
    42901 tgaaactttc cgtgctggca ctcaagccga aggtaagttt gtacgtcagt ctggtggtaa
    42961 aggtcaatac ggtcacgtat ggattgaatt tacaccaaat gaagaaggtg ctggtttcga
    43021 atttgaaaat gcgatcgtcg gtggggttgt tcctcgtgaa tacattccag ctgttgaaac
    43081 tggtttgaaa gatgctatgg aaaatggtgt cttagctggc tatccattag tagatatcaa
    43141 agctaaactt tacgatggtt cataccatga tgtcgattca aatgaaactg ccttccgtgt
    43201 tgctgcttct atggcattac gtgcagcagc taagaaagct aatccagtaa tccttgaacc
    43261 aatcatggct gtagaagttg ttatccctga agattattta ggtgatgtta tgggtcacgt
    43321 aactgctcgt cgtggacgtg ttgaaggtat ggaagctcgc gctggcggcc aacaagttgt
    43381 tcgtgcgatg gttccacttg ctgaaatgtt tggttatgct acaactcttc gttctgctac
    43441 tcaaggtcgt ggtacattta caatgacatt tgaccactac gaagatgtac caaaatcagt
    43501 acaagaagaa atcattaaga aaaacggcgg aaaagctgaa taatttctta aaaccggata
    43561 gtcctgcaaa gagattatcc aaagagacta tatttttaat atagtttcgt gtaaaataat
    43621 tatcgatgat atgggcatgt ggtgtacctt gtgtacatca tatacctatc agacaaataa
    43681 aaaatatatt gtatttttag gaggacattt taaaatggca aaagaaaaat ttgaccgttc
    43741 taaaccacac gttaacattg gtactatcgg acacgttgac catggtaaaa ctacattaac
    43801 agctgcaatc acaactgtac tatctaagaa aaacggcggc caagctatgg cttacgatca
    43861 aatcgatggt gctccagaag aacgcgaacg cggaatcaca atctcaacag ctcacgttga
    43921 gtatgaaaca gatacacgcc actacgctca cgttgactgc ccaggacacg cggattacgt
    43981 taaaaacatg atcactggtg ctgctcaaat ggacggagct atcttggtag tttctgctgc
    44041 tgacggccca atgcctcaaa ctcgtgaaca catcctattg tctcgtcaag ttggtgttcc
    44101 ttacatcgtt gtattcttga acaaagtaga catggttgat gacgaagaat tactagaatt
    44161 agttgaaatg gaagttcgtg acctattaac agaatacgaa ttccctggtg acgatgttcc
    44221 tgtagttgct ggatcagctt tgaaagctct agaaggcgac gcttcatacg aagaaaaaat
    44281 tcttgaatta atggctgcag ttgacgaata catcccaact ccagaacgtg acaacgacaa
    44341 accattcatg atgccagttg aagacgtgtt ctcaattact ggacgtggta ctgttgctac
    44401 aggtcgtgtt gaacgtggac aagttcgcgt tggtgacgaa gttgaagttg ttggtattgc
    44461 tgaagaaact tcaaaaacaa cagttactgg tgttgaaatg ttccgtaaat tgttagacta
    44521 cgctgaagct ggagacaaca ttggtgcttt actacgtggt gttgcacgtg aagacatcca
    44581 acgtggacaa gttttagcta aaccaggtac aatcacacct catacaaaat tctctgcaga
    44641 agtatacgtg ttgacaaaag aagaaggtgg acgtcatact ccattcttca ctaactaccg
    44701 tccacaattc tacttccgta caactgacgt aacaggtgtt gttgaattac cagaaggaac
    44761 tgaaatggtt atgcctggcg acaacgtaac aatggaagtt gaattaatcc acccaatcgc
    44821 tatcgaaaac ggtactaaat tctcaatccg tgaaggcgga cgtacagttg gtgccggtgt
    44881 cgttacagaa atcaaagctt aattcactta agttttaaag taaagcaaca tttattcgga
    44941 cgtaatcgct cggaacgaag gtcttaggat ctttgttccg agctttttta tttattgcag
    45001 gatcaggaaa aaagacagga gtattataaa tagaagaaac acgaaataaa agagtcagta
    45061 ttttctaaat gaaactttat gaaaacaaaa tgttttttac aagaaaaagc cttgctttgt
    45121 gagtttatat atattataat gacaaaggtg cgtttacttt agtgaattgc acagacgtaa
    45181 tcagaatgat ttcgtcggct aagaaacgag aggttgcgac acgcccggac gctttgccac
    45241 gaacgagcgt gacggaaatt ttcgtggagc tatgtctact tttcaaaata ggcgaaggag
    45301 ggaacaagat ggcaaaacaa aaaattcgta tccgtttaaa agcgtatgaa caccgtattt
    45361 tagatcaatc agcggataaa atcgtggaaa ctgcaaaaag aactggagct agcgtgtctg
    45421 gtccaattcc attaccaact gaacgcagtc tttacacaat catccgtgcg actcataaat
    45481 acaaagattc acgcgaacaa ttcgaaatgc gtacacacaa acgtcttatc gacattgtga
    45541 acccaacacc aaaaactgtt gatgctttga tgaagctaga cttaccatct ggtgtaaaca
    45601 tcgaaatcaa attataaaac taaaacaaaa ataatggagg tgtactcatg accaaaggaa
    45661 tcttagggaa aaaagtggga atgacacaaa tcttcactga atctggtgaa ttaattccag
    45721 taactgttgt agaagctact ccaaacgtag tactacaagt gaaaacaatg gaaacggatg
    45781 gctacgaagc tattcaagtt ggttaccaag atatgcgtga agttttatca aacaaacctg
    45841 cgaaaggtca tgttgcaaaa gcaaacacgg ctcctaagcg cttcattcgt gaattcaaaa
    45901 atgttgagct aggagaatat gaagtaggaa aagaaattac agtagatgtt ttccaagcag
    45961 gagacattat tgatgtaaca ggtactacga aaggtaaagg attccaaggg gttatcaaac
    46021 gccacggaca aagccgcgga ccaatggctc acggttctcg ttaccatcgt cgtcctgggt
    46081 caatgggtcc agttgcacct aaccgtgtat ttaaaaacaa acgtcttgct ggccgtatgg
    46141 gtggcaaccg cgtaactatc caaaacttgg aagttgtacg tgtcgatgca gaaagaaatg
    46201 ttatcttgat caaaggtaat gttcctggag ctaaaaaatc tttaattact atcaaatcag
    46261 ctgtgaaagc taaataattg taggaagaaa ggaggaacta aggaatgccg aatgtagcat
    46321 tattcaaaca agatggaagc caaaacggtg aaatcacact taacgaagaa atcttcggaa
    46381 ttgaacctaa tgaaagtgtt gtttacgatg caatcgtaat gcaacgtgcg tcattaagac
    46441 aaggaacaca cgcggttaaa aaccgtagcg ctgttcgcgg cggcggacgt aaaccatggc
    46501 gtcaaaaagg aacaggtcgt gcacgtcaag gatctatccg ctcaccacaa tggcgtggag
    46561 gtggcgtagt ctttggacca acaccacgtt cttacagcta caaacttcct aaaaaagttc
    46621 gtcgtttagc aatgaaatct gtattgtcag aaaaagttgc tgaaaacaac ttggtagcaa
    46681 tcgaaggctt gaacttcgac gcaccaaaaa caaaagaatt caaacaagtt cttgctaact
    46741 tatctatcga ctctaaagta ttggttgttc tagaaaaagg taacgacttt gctgctttat
    46801 cagcacgtaa cttaccaaac gtttctgtag taacttctga taatgtgagt gtgctagacg
    46861 ttgtatcaaa tacaaaagtg ttagcaacac aaactgctct tactcaaatt gaggaggtgc
    46921 ttgcataatg aacttactag acgtaatcaa acgcccagtg atcactgaaa aatcaatgct
    46981 tgccatggat gacaagaaat acacttttga agtggacact cgcgcaaaca aaactttagt
    47041 aaaacaagcg gtagaagctg cttttgacgt taaagtcaaa aacgtgaaca tcgtgaacgt
    47101 acgtgcgaaa ttcaaacgta tgggcaaata tgcaggatat acaaaaaaac gtcgcaaagc
    47161 gatcgttaca ttgactgaag attcaaaaga aatccaatta ttcgaagctg ctgaataagc
    47221 actaatagat aactcattaa attaggaggg aaaaacgtgg cgattaaaaa gtacaaacct
    47281 acctcaaatg gtcgtcgtaa catgacaggt tctgattttg ctgaaatcac aacatcaaca
    47341 cctgaaaaat cattgttaca accattgaaa aaccatgctg gacgtaacaa caacggccgc
    47401 atcactgtac gtcatcaagg tggcggacac aaacgccaat atcgcgtgat cgacttcaaa
    47461 cgtaacaaag ataacgttgt tgcaactgtt caaacgatcg aatatgatcc aaaccgttca
    47521 gctaacatcg cgttagtaca ctatgaagat ggagtgaaag cttacatctt agcacctaaa
    47581 ggactagaag tgggtatgaa acttgtttca ggtccagaag cagatatcaa agtcggaaat
    47641 gctcttccat tagaaaacat tccagttggt actgttatcc acaacattga aatgaaacct
    47701 ggtaaaggtg gacaattgat ccgttctgct ggtacaagtg ctcaagtact tggtaaagaa
    47761 ggcaaatacg tattgatccg cttgaactct ggtgaagttc gtatgatctt agctgcatgc
    47821 cgtgctacaa tcggttctgt aggtaacgaa caacacgaat taatcaacat cggtaaagct
    47881 ggacgctctc gttggatgcg taaacgccca actgtacgtg gtagcgtaat gaaccctaat
    47941 gatcacccac acggtggtgg tgaaggtaaa gctcctatcg gacgtaaagc accagtttct
    48001 ccttggggtc aaccagctct tggttacaaa actcgtaaca aaaaagctaa atcagacaaa
    48061 cttattgttc gtcgtcgcaa aaataaataa ttactttgac catgtgtcgc acattttgag
    48121 aggaggttca ccatgggtcg tagtttaaag aaaggacctt ttgtcgatga gcatttaatg
    48181 aaaaaagttg aagctcaagc aggggttgaa aagaaaaaag ttatcaaaac ttggtcacgc
    48241 cgttcaacag ttttcccaag ttttgttgga tataccatcg cagtttatga tggacgtaaa
    48301 catgtaccag tttacatcca agaagacatg gtaggacaca aattaggtga atttgcacct
    48361 acaagaactt atcgtggaca tgctgctgac gataagaaaa cgaaacgcta atttgagggg
    48421 aggataaatc caaatggcag aacaaatcac atcagctaaa gcaactgcaa aaacagttcg
    48481 cacttcacct cgaaaagccc gtttagtaat tgaccttatc agaggtaaaa gtgtcgcaga
    48541 tgcaatttca atcttgaaat tcacaccaaa caaatctgct ggaatcattg aaaaagtatt
    48601 gatgtcagca gttgcgaatg cagaaaataa ctttgactta gatgttgaaa acttggtagt
    48661 aagcgaagct tttgttaacg aaggacctac aatgaaacgt ttccgtcctc gtgcaaaagg
    48721 atcagcttct ccaatcaaca aacgtacaag tcatatcacg gtagtcgtat cagaaaaata
    48781 aggagggata atcagtgggt caaaaagtac atccaattgg aatgcgtgta ggcatcatcc
    48841 gcgactggga tgctaaatgg tatgctgaaa aagagtatgc tgagttctta cacgaagatt
    48901 taagaatccg taaatttatt tcaactaaac ttgctgatgc tgctgtatca acagttgaaa
    48961 tcgaacgcgc aacaggtcgc gtaaacattt caattcacac agctaaacca ggtatggtta
    49021 ttggtaaagg cggttctgaa gtcgaaagcc taagaaaaga attaaacaaa ttaactggta
    49081 aaagaatcca tatcaatatc gtggaaatca aaaaaccaga tctagatgca aaattagtag
    49141 gtgaaggaat cgcacgtcaa ttagaaaacc gtgttgcttt ccgtcgcgct caaaaacaag
    49201 ccatccaacg ctcaatgcgt gctggcgctc aagggatcaa aactcaagta tctggtcgtc
    49261 taaacggagc agatatcgct cgttcagaag gatactcaga aggaactgtt cctcttcata
    49321 ctttacgtgc ggacattgat tacgcatggg aagaagcaga tacaacatac ggaaaactag
    49381 gagttaaagt gtggatctat cgtggagaaa ttcttccaac taaaaaaaac actgagaaag
    49441 gagggaaata atcatgttag tacctaaacg tgtaaaacac cgtcgtgaat tccgcggaaa
    49501 aatgcgcggg gaagctaaag gcggaaaaga agtagcattc ggtgaatacg gtttgcaagc
    49561 tgttgattca cattggatca caaaccgcca aatcgaagct gctcgtatcg caatgactcg
    49621 ttacatgaaa cgtggtggga aagtatggat taaaattttc cctcacaaat cttatactgc
    49681 caaagcaatt ggggtacgta tgggttctgg taaaggggca cctgaaggat gggttgcacc
    49741 agtaaaacgt ggtaaaatca tgtttgaaat cgcaggcgtt cctgaagaag tagctcgtga
    49801 agcgttacgt ctagcttctc acaaattacc aatgaaaact aagatcgtaa aacgtgagga
    49861 aatgggtggt gaatcgaatg aaggttaaag aaatcagaga attaaccact gccgaaatgc
    49921 ttgatcaaga aaaacaatta aaagaagaat tgtttaatct tagattccaa ttagcaacag
    49981 gtcaattaga aaacactgca cgtattaaag aagtacgtaa atcgattgca cgcatcaaaa
    50041 ctgtgttgcg tgaacaagct aagtaattat ggaaggaggc cattaagcgt atgactgaag
    50101 gaagaaatca acgcaaagtt tatcaaggtc gcgtggtttc agacaaaatg gataaaacaa
    50161 ttaccgttgc tgtcgaaaca aagaaaaacc accctatcta tggcaaacgc atgaactatt
    50221 ctaagaaata caaagtgcat gatgaaaaca acacagcaaa agttggcgac atcgtgagaa
    50281 ttatggaaac tcgtccatta tcagctacaa aacgtttccg tttgttggaa gtagtcgaag
    50341 aagcagttat tatctaataa cacgagattt tcctatatag attgaatgca aaatctgaaa
    50401 ggaggataca caacgtgatc caagcagaaa gtcgtttaaa agtcgctgat aactcaggcg
    50461 cacgtgaaat tttgacgatc aaagtccttg gtggatctgg tcgtaaaact gctaacatcg
    50521 gtgatgtgat cgttgctacg gttaaacaag caacgccagg tggggttgtc aaaaaaggtg
    50581 acgtcgttaa agccgttatc gttcgaacaa aatcaggagc tcgtcgtaca gacggttcat
    50641 atattaaatt tgatgaaaat gctgcagtga ttattcgtga tgataaaagc cctcgtggaa
    50701 cacgtatctt tgggccagtt gcacgtgaac tacgtgaaaa caacttcatg aagatcgttt
    50761 cactagcacc agaagtttta taatcttgag acacttatca aaggaggtgc gaaacagtta
    50821 tgtttgttaa aaaaggcgat aaagttaaag ttatcactgg aaaagacaaa aacaaagaag
    50881 gcgttgtact agcagcgttc ccgaaaaaag ataaagttat tgtcgaaggt gtaaatgtcg
    50941 ttaaaaaaca ccaaaaacct tctcaagctg ctcctcaagg tggaattgtt gagatggaag
    51001 cgccaattca tgtttctaac gtgatggtgg ttgactctac tggtgtagct ggccgagttg
    51061 gctacaaaga agtagacggc aaaaaagtcc gtgtttctaa aaaaaccggt gaagttttag
    51121 ataaataaaa gtttaaggaa ggagggtctt actgaatgaa ccgcctaaaa gaaaaatatc
    51181 ttaaagaagt aactccatca ttgatggaaa aatttaacta tagctctgtt atgcaaacac
    51241 ctaaagttga aaaaatcgtc atcaacatgg gtgttggtga tgcggtatca aacgctaaaa
    51301 acttagataa agcagttgaa gaattaactt tgatcactgg tcaaaaacca atgattacaa
    51361 aagctaaaaa atcaatcgct ggattccgtt tacgtgaagg aatgccaatt ggtgcaaaag
    51421 ttacattgcg cggagaaaga atgtacgaat tcttagacaa attggtttct gtttcactac
    51481 cacgtgtacg tgacttccat ggtgtaagta aaaaagcctt tgacggtcgt ggaaactata
    51541 ctttaggtat taaagaacaa ttgatcttcc cagaagtaga ttatgattta gtagataaag
    51601 tacgtggtat ggacatcgtt attgtaacaa cagcaaactc tgatgaagaa tctcgtgagt
    51661 tgttgacaca attaggcatg ccattccaaa aataattaaa ggaggcgaac tacgtggcta
    51721 aaaaatcaat gattgctaaa aacaaacgtc ctgcaaaatt ttcaacacaa gcttatactc
    51781 gttgcgaacg ttgcggacgt ccacattcag tttatcgtaa gttccatctt tgccgtattt
    51841 gcttccgcga acttgcctat aaaggtcaaa ttcccggcgt gaagaaagct agctggtaaa
    51901 aagtaaattc gcataagaag gaggtaaaag atcaatggtc atgacagatc caattgcaga
    51961 ttttctaact cgtatccgta acgcaaacat ggttaaacat gagtctttag aagtacctgc
    52021 atcaaaaatt aaacgtgaca tcgctgaaat cttgaaacgt gaaggtttcg ttcgtgatgt
    52081 tgaatacatc gaagatgaca aacaaggcgt gatccgtgtt ttcctaaaat ttggtaaaaa
    52141 cggcgaacgt gttatcacaa acttaaaacg tatctctaaa ccaggtttgc gtgcttatgt
    52201 caaagctgac gaagtaccaa aagtattgaa cggtttaggt atcgcaatca tttcgacttc
    52261 tgaaggtgtt gtcactgata aagaagctcg tgaaaaaaat atcggcggcg aagttatcgc
    52321 ttacgtatgg taatcaagta gaatctacaa ggaggtgtct ttaagtgagc cgtatcggaa
    52381 ataaagtcgt tgttatccct gaaggagtaa cagttactca agacggaaac aacgttacag
    52441 ttaaaggacc aaaaggtgaa ttgactcgta ctttttcagc agatatcaaa atgaatatcg
    52501 aaggaaacga agtaactttc actcgtccaa acgacagtaa agaaatgaaa acaattcatg
    52561 gaacaactcg tgcgaacttc aacaacatgg ttgtaggtgt cagcgaaggt ttccaaaaag
    52621 cgttagaact aatcggggtt gggtaccgtg cacaattaca aggatcaaaa cttgtattga
    52681 acgttggtta ctcacatcca gtagaaatca caccaccagc tggagtaact gttgaagtac
    52741 cagctaacac acaagtaatt gttaaaggtg cgaacaaaga agaagttggc gaattagctg
    52801 caaacattcg tggaactcgt cctccagaac cttataaagg taaaggtatt cgttatgttg
    52861 gcgaatatgt acgccgtaaa gaaggtaaaa ctggtaaata atcgtttaga aaaattgcat
    52921 agaagccagc agcaggaaaa aggcatttgg ctgaagttta ccttcaaaaa aatacatttt
    52981 tacttgtgcc gcagcttcta tttttcgaaa cgtatttact gcttgaaata gtagtacaat
    53041 aaaaataaag aggtgacaat tgtgattaca aaaccagata agaacaaaac acgtcaaaag
    53101 agacatcgtc gtgtacgtaa caatatctct ggtactgctg agcgcccacg cttgaacgtt
    53161 tttcgttcta acaaaaacat ctacgctcaa attattgatg acgtagcggg tgtaacgcta
    53221 gcaagtgcct ctaccttgga taaagaaatt tcaggtggaa caaaaacaga agcagcacaa
    53281 gctgtcggta aactagttgc tgaacgtgca gctgaaaaag gcattaaagt agtagtcttt
    53341 gaccgtggtg gataccttta ccatggccgt gtgcaagctt tagctgaagc tgctcgcgaa
    53401 aatggactag aattttagaa gaaggaggaa taccattcat ggtttatatc gatccaaaac
    53461 atttggaatt agaagaccgc gttgttgcaa ttaaccgtgt aacaaaagtt gttaaaggtg
    53521 gacgtcgtct acgttttgct gctttagttg ttgtcggtga caaaaacgga cacgtagggt
    53581 ttggtacagg taaagctcaa gaagttcctg aagcaatccg taaagcaatt gaagatgcga
    53641 agaaaaactt agttgaagta cctatggttg gttcaacaat cccacacgaa gtaatcggtg
    53701 cttttagtgg tggtagaatc ctaatgaaac ctgctgtaga aggttctggg gttgctgctg
    53761 gtggaccagt tcgtgccgta ttagaattag ctggggtagc agatatcact tctaaatctt
    53821 taggctcaaa tacaccaatc aacgttgttc gcgcaacagt tgaaggtttg aaacaattga
    53881 aacgtgcaga agaagttgca gaacttcgcg gcaaatcagt tgaagaatta atcggataag
    53941 gaggacaaca ataatggctg aattaaaagt tactttaaaa cgcagtatta tcggacgtcc
    54001 tcaaaaccaa cgcgatacag ttaaagcgtt aggtcttaca aagattaaca gttcagtggt
    54061 taagccttct aatgaagcaa ttaaaggcat gatcaatact gtttctcacc tagtggacgt
    54121 tgaagaaatt taatttagaa aaatcataac tagaacatta aggaggtgcc aaacctatga
    54181 aacttcatga attaaaacct gctgaaggtt cacgccaagt acgtaaccgt gttggtcgtg
    54241 gtacttcatc tggtaacgga aaaactgccg gacgcggaca aaaaggacaa aaagctcgtt
    54301 caggcggcgg tgtgcgttta ggatttgaag ggggacaaac accattgttc cgtcgtttac
    54361 caaaacgagg attcacaaac gtgaaccgta aagactatgc agtcattaat cttgatgtat
    54421 tgaaccgctt tgaagacgga gctgaagtaa ctcctgttgc tttagttgaa gctggaatcg
    54481 tgaaaaacga aaaagctgga atcaaagtat tagctaatgg ggaactaaac aagaaattaa
    54541 ctgtgaaagc agcaaaattc tctaaagcag ctcaagaagc aattgaagcg gctggtggat
    54601 caatcgaggt gatctaatgt ttagactatt aaaagatgct tttaaagtaa aagacattag
    54661 atcgaaaatc ctatttactg tatttgtgtt gtttgtattt cgcctaggtg cacatattac
    54721 tgtaccaggc gtaaatgctg cttcattgca aaacctttct tctttgccat ttttcaacat
    54781 gttgaacttg gtaagtggta gtgcgatgca aaacttttcc attttctcaa tgggggtttc
    54841 accatacatt actgcttcta tcgtcattca gcttcttcaa atggacatcg tgcctcgatt
    54901 tgttgaatgg tcgaaacaag gggaagttgg tcgtaaaaaa ctgaatcaag cgactcgata
    54961 tctgacatta gtattggcat ttatccaatc tgtcggtatc actgctggat tcaatcaata
    55021 cgctcaatta ggtttcgtga ataatcctaa cgtagcaact tacgtaacga tcggtttgat
    55081 tctaacagcc ggtacgatgt ttgttacttg gctaggagaa cagatcacag aaaaaggtat
    55141 cggaaatggc gtatcaatga tcatttttgc aggtatcatt tctagattgc ctgaaagtat
    55201 cagagaaatt tatgaagatt actttataaa tattgatcct tcagacatat ggaaatctgc
    55261 tatttttgtg gccattttac tagtagcggt cttgttgatc gtgacattcg taacattttt
    55321 ccaacaagct gaacgcaaga tcccgatcca atatacgaaa cgcgtagctg gcgcgcctac
    55381 aagcagctat ctgccgttga aagtaaatgc agctggagtt attccagtta tctttgctag
    55441 ttcgtttatt gctacgccaa atgctgtttt acaagcattg agcggtagat tcggttctga
    55501 aaactggtac aaagtgatga tggagatctt taactataat acagcacctg gtgctacgat
    55561 ttatacgatt ctgatcgttg ccttcacttt cttctacgcc tttgttcaag taaaccctga
    55621 gaaattagcg gaaaacttgc aaaagcaagg aagttatata ccaagcgtac gccctggtaa
    55681 ggggactgaa gagtatgtct caagattact gatgcgttta agtacagttg gtgcagtctt
    55741 ccttggttta gtggcattgc ttccaatcat tgctcaaatg gtttgggatc ttccacaatc
    55801 aatcggatta ggcggtacaa gcttactgat cgttatcggt gtagctttag aaactgcgaa
    55861 acagttagaa ggcttaatgc tgaaacgtaa atatgttgga ttcattgagt aagaaagcgt
    55921 gttgaggttt cccctcaaca cacgttctca cacatttatt aggagggaaa acaatgaacc
    55981 tcattttaat ggggctgcca ggcgcaggta aaggaacaca agctgaaaaa atcattgatg
    56041 cttatggtat tccgcacatc tcaacaggag atatgttccg cgcagcgatg caaaacgaaa
    56101 cagctcttgg cctggaagca aagtcttata tggataaagg tgcattagtt cctgatgaag
    56161 taacaaatgg aatcgtgaaa gagcgactag ctgaaccaga tacagagaaa ggcttcttat
    56221 tagatggctt tccacgtacg ctagatcaag caaaagctct ggacgcaatg ctaaaagatt
    56281 tgaataaaaa aattgatgct gtcatcgata tccatgttgg tgaagaaatc ttggtcgaac
    56341 gtctagccgg ccgatttatc tgcagcaatt gtggagcaac ttaccataaa attttcaacc
    56401 ctacaaaagt tgaagacaca tgtgatcgtt gcggtgggca tgaattctat caaagagaag
    56461 atgataaacc tgagacggtt aaaaatcgtc tggctatcaa catcaaaaat agtgaaccaa
    56521 tcttggctta ttataaagaa caaggtttgc taaacactat tgatggtgct cgtgaaatcg
    56581 atgctgtatt tgcagatgta caaaaaatca ttgaaaaata gcacgattgc ccgtagccga
    56641 cttgcattat gcagttactc ttgtcaagtt caataaatta tgatagaata tgtcagtccg
    56701 acttctagag aatcctctag atgatccatt ttgagaattt tgaggtggga actgcagttt
    56761 ccgccatttt atcgtgtgaa aatgcgaaac aagtacaagg aggtactgtg cgtggcaaaa
    56821 gaagatatga ttgaagtcga aggtacagtc gtcgaaactt tgccgaatgc aatgtttaaa
    56881 gttgaactag aaaacggaca ccaagttctt gctactgttt caggtaaaat tcgtatgcat
    56941 tacatccgta tcttacctgg tgacaaagta acggttgaat tgtctccata cgatcttaac
    57001 cgtggccgta ttacttatcg ctttaaataa ttgtactccg taaaactaca ggaggtatta
    57061 tcatgaaagt aagaccatca gtaaaaccaa tgtgcgaaca ttgtaaagta attcgtcgta
    57121 aaggacgcgt tatggtgatt tgcccagcaa atccaaaaca taaacaacgt caaggataat
    57181 tggaggtgct ataaatatgg ctcgtattgc aggagtagat attcctcgtg ataaacgtgt
    57241 agtagtttca cttacttata tctatggtat tggtaacact actgctaaaa agatcttagc
    57301 tgatgctggt gtatctgaag atgttcgcgt tcgtgaatta acgaatgaac aaacagatgc
    57361 tatccgtgca gaagtagata aattaaaagt tgaaggggat cttcgtcgtg aagtgaactt
    57421 gaacatcaaa cgtttgatgg aaatcggttc ttaccgtgga atccgtcatc gccgtggatt
    57481 gcctgttcgt ggacaaaaca cgaaaaacaa tgcacgtact cgtaaaggcc cagctcgcgc
    57541 tatcgctggc aagaaaaaat aattcttaag tgaaggaggt taaaacttca tggcagcaaa
    57601 aaaagtgaat cgtaaacgcc gtgtgaagaa gaatatagaa gcaggtattg cacatatcca
    57661 ttctacattc aataacacta tcatcatgat cactgatact cacggaaatg cattagcgtg
    57721 gtcatcagct ggttcattag gtttcaaagg aagcaaaaaa tcaactcctt ttgccgctca
    57781 aatggcagca gaaactgcta caaaagcagc aatggaacac ggattaaaga ctgttgaagt
    57841 aacagttaaa ggacctggtt ctggacgtga agcagcaatt cgttcattac aagctacagg
    57901 tttagaagtg actgcaattc gtgacgtgac tccagttcct cataatggtg cccgccctcc
    57961 aaaacgccgt cgtgtttaat gagtgccgct cattttgagt tttatcagta acgtcattga
    58021 acaagacact tttcgttttg aaaggggtaa agataagaat gattgagttc gaaaaaccaa
    58081 gaatcgcaaa aattgatgaa gaaaaagatt atggcaagtt catcgttgaa cctcttgaaa
    58141 gagggtatgg gactacttta gggaattccc tacgtcgtat tttattatct tctttgccag
    58201 gtgctgccat cactaatatt caaatcgatg gtgtactgca tgaattctct accatcaaag
    58261 gtgttagaga agacgtcact caaatcatct tgaacattaa aggcttagcg ctgaaaatgt
    58321 atggccaaga agaaaaaacc cttgaaatcg atattaccgg acctgctaca gtaactgctg
    58381 gcgatattat cgttgatagt gatgtagaaa ttcttaacaa agatatgtac atctgtagtg
    58441 tctctgaagg agctacgttc catgctcgct taacagtgaa acctggacgt ggttatgttc
    58501 aagcagatga aaataaaaaa gaagatatgc caattggcgt tcttccagtc gattcaatct
    58561 acacacctgt tcgtcgtgtg aactatcaag ttgagaacac acgtgttgga caccgtgaag
    58621 attttgataa attgacgatg gagatttgga cagatggttc aattgaaccg ttggaagcaa
    58681 tgagtttgtc tgcgaaaatc atgactgaac atttggatat ttttgtgaac ttaactgatg
    58741 aagcaaaaaa tgctgaaatc atggtcgaaa aagaagaaac acaaaaagaa aaaatgttgg
    58801 aaatgacgat cgaagagtta gacttgtctg ttcgctctta caattgtttg aaacgtgcag
    58861 gaatcaatac tgtacaagaa cttacaaata aatctgagcc tgaaatgatc aaagtccgta
    58921 acttaggacg taaatcatta gaagaagtta aagcaaaatt gcacgactta ggtttaggtt
    58981 tacgtaaaga agattaaaac cttttacgaa ggagggaaac caacgtgagt tatcgtaaac
    59041 taggacgcac atctagccaa cgtaaagcga tgttgcgtga tttaacaact gatttattaa
    59101 tcaacgaacg tattgtgact actgaagctc gtgcgaaaga agttcgctca actgcagaaa
    59161 aaatgatcac tttaggtaaa cgcggagatt tgcatgcacg tcgtcaagct gcggctttcg
    59221 tacgtaatga agttgccagc gtgcgtgaag aaaatgagga catcgtcatt gaatcagctt
    59281 tacaaaaact gttcaacgat attgcacctc gttacgcaga acgtcaaggc ggatacacac
    59341 gcattttgaa gacagaacca agacgcggtg atggtgcacc aatggttgtc ttagaacttg
    59401 tctaaaatca cactaataac atcactttat agatgattct tttagagtgt tatgatgttg
    59461 gaagatattt ttccgagtct agctcagcgc tgctcctcaa gcgaatatcg cttggggagt
    59521 aagcactcat cataaagtgt ttttttatac cttcaattac ctgtcatgac agatatgttt
    59581 gaaggcataa aaaaacattt taagcgagaa ataattgaaa attttgtctt tttttgatag
    59641 tgttagtagg aactttagga tgaagaagga gtaatcatgg agccaattat tgaattagaa
    59701 aagataaatt ataaatacca gccagatgat cttcgccccg cattgaaaga tgtctccttt
    59761 acaattgata aaggtgagtg gatcgctatt attggacaca atggttcagg aaaatcgaca
    59821 cttgccaaaa cgatcaatgg attgcttctg ccagaatcag ggatcgtgaa agtgggaaat
    59881 caaatattgg atgaagaaaa tatttggacg atccgacaga tggttggaat ggtttttcaa
    59941 aatccagaca atcagtttgt tggttcgaca gtagaagatg acgttgcttt tggtcttgaa
    60001 aatcaaggga ttcccagaga agaaatgcta gtgcgtgtga aagatgcact tgagaaagtt
    60061 agaatggctg agtttgcttc acgcgagcct gctcgtttat caggagggca aaaacaacgt
    60121 gttgccattg ccggcgtggt tgccttacga cctgatatca ttattttaga tgaagcaacc
    60181 agtatgctag atccagaagg tcgtgaagaa gtgatctcta cgatcaagaa gatcaaagaa
    60241 gaaagtcaat tgaccgttat atctatcact catgatattg atgaagcagc taatgccaat
    60301 cggatactag tgatgagaca aggcgaactt gtccgtgaag gtacaccaaa agaaattttt
    60361 tctgctggtc ctgaactgat cgacttaggt ctagatctac catttcctga aaaactgaag
    60421 agcgcactga aagaacgtgg ggttgatgtg cccagtgaat atatgacaga agaaaggatg
    60481 gtggattggt tatggacatc cgttttgaac aagtagactt cacttatcag ccgaatacac
    60541 catttgaaca aagagcctta tttgacatca atatgacgat caaagaaaac agttatactg
    60601 cattagtagg gcataccgga agcgggaaat caaccttact tcagcatttg aatgcgcttg
    60661 ttaagccaac aagcggtaca gtccatattg gagaacgaga tattcagccg gatacggata
    60721 ataagaattt aaagcccatc cgaaaaaaag ttggcatcgt ctttcagttt ccagaagcac
    60781 agctattcga agaaacggta gcaaaagaca ttgctttcgg tcctaaaaac tttggtgtca
    60841 gcgaagaaga agcactagtc ctagcaaaag aaacattaga acaagttggg ctggatgaaa
    60901 gctatttgga acgttcgcca tttgaacttt caggagggca aatgcgtaga gtagcaatcg
    60961 ctggtgtgct tgccatgagg ccggaagtac ttgtattgga tgaaccaacg gcaggacttg
    61021 atccccaggg tagaaaagaa atgatggaga tgttttggcg tcttcataag gaacagcaga
    61081 tcactattgt attagttacg catttaatgg atgatgtagc caattttgca gattatgtct
    61141 atgtgttgga aaagggacga atcgttaata gcggggagcc gcaagaggtc tttcaaaaca
    61201 ttgaatggct aaaagaaaaa caactaggcg tacctactgc caccgagttt gcagaagaat
    61261 taatggctaa agggatgaac tttgctacct tgcctttgac agctgaagaa ttagcagacg
    61321 ctatcgtcca ttatgctgga ggaaatgccc atgatgaata aattgatatt tggtcgttat
    61381 atgcctggag attccttgat ccatcgattg gatccccgag ctaaattatt agccagtttt
    61441 tattttatcg gaatcatttt tttagcaaat aattgggaaa cgtacctttt gttggcattt
    61501 ttcacattac tttctgtctt cttgtcaaaa gtagatttga aattttttat ccgaggcatt
    61561 cgcccattga tctggctaat cctcttcact gtagctttgc aggtcttgtt tacaagtggc
    61621 ggagaaactt attggagttg gggtgttttc catatcactg aatttggtgt gatgaacggc
    61681 ctctttattt tctgtcgatt cgtgttgatc atttttatgt cgactctact cacgcttact
    61741 acaccgcctt tggaattatc ggatgcgatt gagtacttgc ttcgtccatt gaaagccgta
    61801 cggttcccag tccacgaaat ttcattgatg ctgtcgattg ctcttcgttt tgtgcctaca
    61861 ttgatggacg aaacagaaaa gatcatgaac gctcagcgcg ctcgcggtgt tgattttggt
    61921 gaaggaaacc tagttcagaa aatgaaagca gtcattcctt tgctgattcc tttatttgtc
    61981 agcagcttca accgtgcgga agatcttgcg actgctatgg aagcaagagg ctacaaaggt
    62041 ggggaaggaa gaacgaaata tcgtgtattg cattggcata atagagacac gatggttatc
    62101 attgcttttg tattattaac tgtgctactg atctttttga gaggataaac gttcagtggg
    62161 ccgctatcta ttcttttctt gctgatctgt ttgcaagaaa ggatgcgagc agtgtatgac
    62221 aagaaatatt agggtctgtg gcagactaag gtcacaggcc tctttctttt atctgaaaag
    62281 aaagaacgaa aaaattttat aaaaaaatca ttattccaga taacctttta ggaacaaagg
    62341 agagaaaaac atggtacgtt acaaagcaat cattgcatac gacggaacaa attttaatgg
    62401 attccaaaaa cagccaaatg ggcgtactgt tcaagaagaa gtagaaaaaa cattacaaaa
    62461 aatggcaaat ggaaaagaaa tcacggtctt tggttcggga aggacagatg ccggagtaca
    62521 tgcgattggg caagtaatcc attttgatta tccagaggag cgtccgttag aacgaatgcg
    62581 tttcgcgcta gatacccagt caccagagga tattgctgta agacaagtag aaattgtttc
    62641 agaagacttc cacgcaagat atttggtcaa agaaaagacg tatcaatttc gagtggatat
    62701 agggaaacca cgcagtcctt ttcgacgcca ttatgcaagt tattttcctt accctcttga
    62761 tttggaaaaa attcagcggg cgcttcctga tttattaggg actcacgatt tcacctcttt
    62821 ttgtgcatca ggaagctcga tagaggataa agtacgtacg atctacgagg ctaagatgga
    62881 ggtaaatgaa acaaaagacg aattgttgtt tacatttagg ggaaatggct tcttgtataa
    62941 gatgatacgg atcttagtag gaacgctttt gaaaattggc aatggccgat tgcctgaaga
    63001 tagtatccca gatattattg cgaaaaaaga tcgtaatgca gcaggaccta cagcacatcc
    63061 tgaaggactt tatttgtatg aagtgaaata tgaataagag gttgtgacag aagtggtcag
    63121 cttcaagaaa taagaaggaa tttacgaaaa ttacttctca aaattttgca aaatttcggc
    63181 ttattttcga aggagctact tctggaacac cgtgaatcag aggttgtgaa aaagctgccc
    63241 tgcatcaagt aataagaaca accaaacaaa aatagctcgt catatttttc gtttggttgg
    63301 gcttattacc gcagatgcaa gcttttgaac accgtttaag gaagaggttg tgaaatcagc
    63361 gttttgacct gagtattaga gaaacaaacg gaaaaatagt tcctcatatt ttgccgtttg
    63421 ttgagctaat accgaaggtc agctgattga acaccgttta agaaagaggt cgtgagcctg
    63481 tcatttaact ctgagtcaca agtaacaatt tcaaaaaaca gcttctcatc tttgatgaat
    63541 atcgtgactt gtggacgagg cgttgataag tgaatcatct ttttgttacc tattttttct
    63601 gtaaccaaaa aacgatggaa cgttgttttg attgccctta atgaggacag tcggaacagg
    63661 tttgtcattt ttatatttaa atggcacaaa tttttctaat tatttgtcat ttagcgctga
    63721 aaatttttgc tatttatcta aaaaagtgat aactacttaa gatgaagcag aatatttacg
    63781 ccatacggca tacaaccgcg aaaaatataa aaaaaagaaa acgattgaac gcgtttttgc
    63841 agtcgcaaag gaaaagcatg gaatgcgcta catcaagtat cgagacttgg aaaacaatca
    63901 ggtgtatacg ctgattgttt ttgctgcaat gaatctgaaa aagttgtcca cttggcagtt
    63961 ggaacatatg tcttcatatc ttttattata caaaaatagc aaaagcacca gtctacactc
    64021 ttagtaaaga ggaaactgat ccttttgtct acattcttaa agtacttaaa ctaagtactt
    64081 tattttactc tttaggattg atacagtagc atctatccct ttattaataa tcttttattt
    64141 ttttaaataa agatgttgtc tccatcttca ggcactaaaa ctttttcgga aattcctttt
    64201 tctttattga aagactttaa ttcttctctt gacagtcccc aatggtttac agcttccata
    64261 tgaacggcaa taattgtgga atctggtatt gctttatgca attcatataa atcgtctttc
    64321 cccataataa gagattctcc aactaaaaaa tgattatctc cagcatttgc tactatgatt
    64381 tctggattat actgatcaat agtttgttta acagcttcat accaaactgt atctcctgta
    64441 aagtatagtg tcttctcagt cgaatgtttg aaaacaatac cgcaaacatt acctacataa
    64501 ttcaagattt ctcctctgcc atgtttgcct tttgttttaa ccaattgtat agattcaaaa
    64561 actgtgtctt ctcgtagtac ctccacattt ttaaaaccat atagtcgaat ttcattcgca
    64621 tcattttcat cttgcacaaa taattttatt tctttaggta ggacctcttt cgctatatcg
    64681 tcccaatgat ctagatgtaa atgtgttaca ataacagcat caataccgtt gataatatct
    64741 tcgactggca ttggcaaatc aactagagga ttcatttgat cttttcttgg tgatggaaaa
    64801 ggacctttcg aaataaatgg tggaagtgtt cctttttccg ctaacattgg atcaattaaa
    64861 aattttttac ctccatagtc taagatagct gttgcattac gaatgtgatg tatattcata
    64921 aacgttgtct cctttttgtt gatatgaaat atttttagta taattcaatt ccatacaata
    64981 aataaaccga acaaaaaaag tcttttacta tttttactta atttatgaaa ggttgtttac
    65041 catgttagac caaacagata taaatatcat tgaggaacta tcaaaaaata gtcgaatcac
    65101 aatgaaagaa cttggagaaa aagtacattt gactggaccc gctgtctcgg cgagagtgac
    65161 aaaactagag gaaagtggag ttattgaaaa ttatacagta aaattaaata tggaaaagct
    65221 agggttttcg attcacgctt ttttaattat aattacgcaa aatttaaatc ataaacccta
    65281 tttatcattt attaaaaatc atgaaaaatt cttgattaga aattataaga ttagtggagg
    65341 gggctgttat cttttgga
//
LOCUS       DAYYEF010000008        61712 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000008 DAYYEF010000000
VERSION     DAYYEF010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61712
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.008"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(132..509)
                     /locus_tag="ACHA1B_000662"
     CDS             complement(132..509)
                     /locus_tag="ACHA1B_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701452.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            765..1493
                     /gene="purC"
                     /locus_tag="ACHA1B_000663"
     CDS             765..1493
                     /gene="purC"
                     /locus_tag="ACHA1B_000663"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004639 -
                     phosphoribosylaminoimidazolesuccinocarboxamide synthase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HFM8701453.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1493..1747
                     /gene="purS"
                     /locus_tag="ACHA1B_000664"
     CDS             1493..1747
                     /gene="purS"
                     /locus_tag="ACHA1B_000664"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HFM8701454.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1749..2420
                     /gene="purQ"
                     /locus_tag="ACHA1B_000665"
     CDS             1749..2420
                     /gene="purQ"
                     /locus_tag="ACHA1B_000665"
                     /EC_number="3.5.1.2"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HFM8701455.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2421..4643
                     /gene="purL"
                     /locus_tag="ACHA1B_000666"
     CDS             2421..4643
                     /gene="purL"
                     /locus_tag="ACHA1B_000666"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004642 -
                     phosphoribosylformylglycinamidine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HFM8701456.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4628..6067
                     /gene="purF"
                     /locus_tag="ACHA1B_000667"
     CDS             4628..6067
                     /gene="purF"
                     /locus_tag="ACHA1B_000667"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004044 - amidophosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HFM8701457.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6090..7142
                     /gene="purM"
                     /locus_tag="ACHA1B_000668"
     CDS             6090..7142
                     /gene="purM"
                     /locus_tag="ACHA1B_000668"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004641 -
                     phosphoribosylformylglycinamidine cyclo-ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HFM8701458.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVQESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            7139..7717
                     /gene="purN"
                     /locus_tag="ACHA1B_000669"
     CDS             7139..7717
                     /gene="purN"
                     /locus_tag="ACHA1B_000669"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004644 - phosphoribosylglycinamide
                     formyltransferase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HFM8701459.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7714..9249
                     /gene="purH"
                     /locus_tag="ACHA1B_000670"
     CDS             7714..9249
                     /gene="purH"
                     /locus_tag="ACHA1B_000670"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0003937 - IMP cyclohydrolase activity
                     [Evidence IEA];
                     GO_function: GO:0004643 -
                     phosphoribosylaminoimidazolecarboxamide formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HFM8701460.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9265..10539
                     /gene="purD"
                     /locus_tag="ACHA1B_000671"
     CDS             9265..10539
                     /gene="purD"
                     /locus_tag="ACHA1B_000671"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004637 - phosphoribosylamine-glycine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009113 - purine nucleobase biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HFM8701461.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10661..11575
                     /locus_tag="ACHA1B_000672"
     CDS             10661..11575
                     /locus_tag="ACHA1B_000672"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HFM8701462.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11708..13273)
                     /locus_tag="ACHA1B_000673"
     CDS             complement(11708..13273)
                     /locus_tag="ACHA1B_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8701463.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13266..14717)
                     /locus_tag="ACHA1B_000674"
     CDS             complement(13266..14717)
                     /locus_tag="ACHA1B_000674"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFM8701464.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14731..15747)
                     /locus_tag="ACHA1B_000675"
     CDS             complement(14731..15747)
                     /locus_tag="ACHA1B_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8701465.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15967..17055
                     /gene="chvE"
                     /locus_tag="ACHA1B_000676"
     CDS             15967..17055
                     /gene="chvE"
                     /locus_tag="ACHA1B_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     substrate-binding protein"
                     /protein_id="HFM8701466.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17109..18635
                     /gene="mmsA"
                     /locus_tag="ACHA1B_000677"
     CDS             17109..18635
                     /gene="mmsA"
                     /locus_tag="ACHA1B_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     ATP-binding protein"
                     /protein_id="HFM8701467.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18637..19842
                     /gene="mmsB"
                     /locus_tag="ACHA1B_000678"
     CDS             18637..19842
                     /gene="mmsB"
                     /locus_tag="ACHA1B_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multiple monosaccharide ABC transporter
                     permease"
                     /protein_id="HFM8701468.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20099..21076
                     /gene="guaC"
                     /locus_tag="ACHA1B_000679"
     CDS             20099..21076
                     /gene="guaC"
                     /locus_tag="ACHA1B_000679"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902560 - GMP reductase complex [Evidence
                     IEA];
                     GO_function: GO:0003920 - GMP reductase activity [Evidence
                     IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HFM8701469.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21340..22764
                     /locus_tag="ACHA1B_000680"
     CDS             21340..22764
                     /locus_tag="ACHA1B_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HFM8701470.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            complement(22806..23063)
                     /locus_tag="ACHA1B_000681"
     CDS             complement(22806..23063)
                     /locus_tag="ACHA1B_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701471.1"
                     /translation="MPIRILTALVNKITIRKAFYISSAFFLFSNQTYNHLFLFKNVGV
                     IQFCCKHLFYLHIVNGRTNNGFFLVSLYRILFPKKKKQLEI"
     gene            23225..24334
                     /gene="pdhA"
                     /locus_tag="ACHA1B_000682"
     CDS             23225..24334
                     /gene="pdhA"
                     /locus_tag="ACHA1B_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA];
                     GO_function: GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HFM8701472.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24337..25314
                     /locus_tag="ACHA1B_000683"
     CDS             24337..25314
                     /locus_tag="ACHA1B_000683"
                     /EC_number="1.2.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HFM8701473.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25339..26982
                     /locus_tag="ACHA1B_000684"
     CDS             25339..26982
                     /locus_tag="ACHA1B_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HFM8701474.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26990..28396
                     /gene="lpdA"
                     /locus_tag="ACHA1B_000685"
     CDS             26990..28396
                     /gene="lpdA"
                     /locus_tag="ACHA1B_000685"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HFM8701475.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28558..28833
                     /locus_tag="ACHA1B_000686"
     CDS             28558..28833
                     /locus_tag="ACHA1B_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HFM8701476.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28839..29606
                     /locus_tag="ACHA1B_000687"
     CDS             28839..29606
                     /locus_tag="ACHA1B_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HFM8701477.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29774..31603
                     /gene="typA"
                     /locus_tag="ACHA1B_000688"
     CDS             29774..31603
                     /gene="typA"
                     /locus_tag="ACHA1B_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HFM8701478.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31864..33636
                     /gene="recQ"
                     /locus_tag="ACHA1B_000689"
     CDS             31864..33636
                     /gene="recQ"
                     /locus_tag="ACHA1B_000689"
                     /EC_number="5.6.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HFM8701479.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33750..34052
                     /locus_tag="ACHA1B_000690"
     CDS             33750..34052
                     /locus_tag="ACHA1B_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HFM8701480.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34055..35218
                     /locus_tag="ACHA1B_000691"
     CDS             34055..35218
                     /locus_tag="ACHA1B_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFM8701481.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35244..38672
                     /locus_tag="ACHA1B_000692"
     CDS             35244..38672
                     /locus_tag="ACHA1B_000692"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004736 - pyruvate carboxylase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009374 - biotin binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006090 - pyruvate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HFM8701482.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38693..39817
                     /locus_tag="ACHA1B_000693"
     CDS             38693..39817
                     /locus_tag="ACHA1B_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP-associated domain-containing protein"
                     /protein_id="HFM8701483.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39798..40244
                     /locus_tag="ACHA1B_000694"
     CDS             39798..40244
                     /locus_tag="ACHA1B_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFM8701484.1"
                     /translation="MIAVIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESA
                     KVCQLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQ
                     LQSLLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40228..40566
                     /locus_tag="ACHA1B_000695"
     CDS             40228..40566
                     /locus_tag="ACHA1B_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HFM8701485.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40685..41245
                     /gene="rsmD"
                     /locus_tag="ACHA1B_000696"
     CDS             40685..41245
                     /gene="rsmD"
                     /locus_tag="ACHA1B_000696"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052913 - 16S rRNA
                     (guanine(966)-N(2))-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HFM8701486.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41242..41733
                     /gene="coaD"
                     /locus_tag="ACHA1B_000697"
     CDS             41242..41733
                     /gene="coaD"
                     /locus_tag="ACHA1B_000697"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004595 - pantetheine-phosphate
                     adenylyltransferase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HFM8701487.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41723..42766
                     /locus_tag="ACHA1B_000698"
     CDS             41723..42766
                     /locus_tag="ACHA1B_000698"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SepM family pheromone-processing serine
                     protease"
                     /protein_id="HFM8701488.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            42925..43653
                     /locus_tag="ACHA1B_000699"
     CDS             42925..43653
                     /locus_tag="ACHA1B_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HFM8701489.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            43769..44014
                     /locus_tag="ACHA1B_000700"
     CDS             43769..44014
                     /locus_tag="ACHA1B_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFM8701490.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            44011..44229
                     /locus_tag="ACHA1B_000701"
     CDS             44011..44229
                     /locus_tag="ACHA1B_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HFM8701491.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            44365..44904
                     /locus_tag="ACHA1B_000702"
     CDS             44365..44904
                     /locus_tag="ACHA1B_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HFM8701492.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            44897..47170
                     /locus_tag="ACHA1B_000703"
     CDS             44897..47170
                     /locus_tag="ACHA1B_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0009290 - DNA import into cell involved in
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HFM8701493.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            47208..48254
                     /gene="holA"
                     /locus_tag="ACHA1B_000704"
     CDS             47208..48254
                     /gene="holA"
                     /locus_tag="ACHA1B_000704"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HFM8701494.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(48343..48597)
                     /gene="rpsT"
                     /locus_tag="ACHA1B_000705"
     CDS             complement(48343..48597)
                     /gene="rpsT"
                     /locus_tag="ACHA1B_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HFM8701495.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(48997..49266)
                     /locus_tag="ACHA1B_000706"
     CDS             complement(48997..49266)
                     /locus_tag="ACHA1B_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701496.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(49528..49656)
                     /locus_tag="ACHA1B_000707"
     CDS             complement(49528..49656)
                     /locus_tag="ACHA1B_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701497.1"
                     /translation="MFEKLKYFIGTIGWFLLAVLLILGLAYLLFPDLIQNVFDTAF"
     gene            complement(49736..50191)
                     /locus_tag="ACHA1B_000708"
     CDS             complement(49736..50191)
                     /locus_tag="ACHA1B_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HFM8701498.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(50329..52257)
                     /locus_tag="ACHA1B_000709"
     CDS             complement(50329..52257)
                     /locus_tag="ACHA1B_000709"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFM8701499.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(52454..53287)
                     /locus_tag="ACHA1B_000710"
     CDS             complement(52454..53287)
                     /locus_tag="ACHA1B_000710"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0050380 - undecaprenyl-diphosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0016311 - dephosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HFM8701500.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(53479..54183)
                     /locus_tag="ACHA1B_000711"
     CDS             complement(53479..54183)
                     /locus_tag="ACHA1B_000711"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFM8701501.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(54206..54832)
                     /locus_tag="ACHA1B_000712"
     CDS             complement(54206..54832)
                     /locus_tag="ACHA1B_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFM8701502.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            55158..57533
                     /locus_tag="ACHA1B_000713"
     CDS             55158..57533
                     /locus_tag="ACHA1B_000713"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HFM8701503.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(57557..58048)
                     /locus_tag="ACHA1B_000714"
     CDS             complement(57557..58048)
                     /locus_tag="ACHA1B_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HFM8701504.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            58235..59155
                     /locus_tag="ACHA1B_000715"
     CDS             58235..59155
                     /locus_tag="ACHA1B_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFM8701505.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            59309..59653
                     /locus_tag="ACHA1B_000716"
     CDS             59309..59653
                     /locus_tag="ACHA1B_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HFM8701506.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(59843..60343)
                     /locus_tag="ACHA1B_000717"
     CDS             complement(59843..60343)
                     /locus_tag="ACHA1B_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8701507.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            60871..60954
                     /locus_tag="ACHA1B_000718"
     tRNA            60871..60954
                     /locus_tag="ACHA1B_000718"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:60905..60907,aa:Leu,seq:cag)
     gene            complement(61278..>61712)
                     /locus_tag="ACHA1B_000719"
     CDS             complement(61278..>61712)
                     /locus_tag="ACHA1B_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HFM8701508.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        20241 a        10663 c        13217 g        17591 t
ORIGIN      
        1 caaaaaagaa gcagatccgt tagcggttct gcttctttta gtttattata ttttcttatc
       61 aataatagga acctgatttt aaaagcggct acctctttac cgtgcctctt tacatacaaa
      121 aaatagagga attaagcgta aatggcttgg ctattataac taaaatgctg gttatggaga
      181 tgttgcagca agttttcgag aaaagcgtat tccatctctt gtccattgaa taagatctgg
      241 atacgataat gatttttgaa acgcttctgt tcatgaatct gactgattga aagttcgcct
      301 ttgtgttctg tctgataaag aaaagtcctt ttacggcatt cagcacagcg cttggttgct
      361 cggcggattt ttcggaatgt ataaaaacta gtatctttat tgcataaata aacgtctttg
      421 atcgacagca aatcattata tagacaggaa cgttcttcag ctgttaattc tgataaaaaa
      481 agctgacctt gttttattgc atcttccatc ggcaagtgcc tcctcgaacc cattatccaa
      541 atttttagtt aattctaata taccatcatt aagtataaat gtaaacgctt gttgatggta
      601 taagattttc gtttctgata aaacacgaac attaaaagaa tctaatgcct taaatgtaca
      661 tatttttgtt gatttataaa aagatgattg ctaaaattta aagtgaaaaa acgaacaaaa
      721 aacgatgtat ttgcttttaa tgtaaataaa aaggagagac gtacatggag aagaaagaac
      781 ttttgtatga aggaaaagcc aaaaaaatat atcttacttc tgatgagaac ttgatttgga
      841 tagaatattt agatcaagca actgcgttga atggcgcgag gaaagaccag ataagtggaa
      901 aaggagaatt gaataatcaa atcacaagtg caattttccg ttatctgact caaagaggaa
      961 taaaaaatca ttttattgaa caattgtcta aaaccgaaca attagcaaaa aaagtacaaa
     1021 ttatccctct ggaagtggtt atccgaaata ttgcagcagg aagtttctca aaacgtctag
     1081 gtgttcccga aggtaaagaa ttcatcaaac caatcattga attctactat aaggatgacc
     1141 agttggatga tccatttatc aatgaagagc atatctattt cttacaactt gcaaagccgg
     1201 aagaaatcag tgagctgaaa gcccaagcgt tggctattaa tgaaattttg accgaattat
     1261 ttgctaaggt cggtttggtt ttagtagatt tcaagctaga atttggccgg tcgaatggac
     1321 aaattttgct tgcggatgaa gtaacaccgg atacttgccg attatgggat gaacgtacga
     1381 atgaacatat ggacaaagac gtttaccgca gagatctagg tgatttgatc ccagtctatc
     1441 aagaagtata taaccgtcta tcggaactaa ctgaagaaaa ggagcgagta tgatgtattt
     1501 cgtaaaagta tatgtaacct ataaagattc agtgttagat cctcaagggg aggcagtaaa
     1561 aaaagcagtc catcgtatgg gatatgaaac aatcgaagat atccgaatag gaaaatactt
     1621 tgagatacaa cttgctgatg cagaagaacc aatcgataca gtgattgaaa cgatttgtga
     1681 caagctgctt gcaaatgtaa atatggaaac ataccgatat gaaatcaaaa aaatggagga
     1741 agtataacat gaaatttgcg gtcatcgttt ttccaggttc aaattgtgac gcagatatgt
     1801 tatgggcagt tcgcgagatc atgggcgctg atgccgaatt tgtacggcat gatgagtcct
     1861 ctttagaagg atttgatggg gttttactgc cgggaggatt ctcctatggt gactatttga
     1921 gatgcggtgc gattgctcgg ttttctacaa tcatggaaga agtgattcgt tttgctgaag
     1981 aagggaaacc agtattcggt acatgcaatg gattccagat attgacagaa gcaggacttt
     2041 tgccaggtgt actgagacga aatgagtctt tgcattttat ttgcaaaact gtaccattga
     2101 aagtcaaccc caagacggcc tttacttcag agtatgaagc cgacgaaata atctatcttc
     2161 cagttgctca tggggaagga aattatttct gtgacgaaga aacacttcaa gaactaaaaa
     2221 aaaataatca gattgccttt acttataatg acaacatcaa cggcagcgtg gaaaacattg
     2281 cagggattac gaacaaagca gggaatgtgt taggaatgat gcctcatcca gaacgtgcag
     2341 tagaagactt gctaggatca gaagatggga aacggttctt tgcttccatt ttaaaaaact
     2401 tcggaaaggt gaccgtatag atgaaaacat tgaaagaacc gacagctgaa gagatcaaga
     2461 aaaaaagaat ctatgccgaa tggggattga ctgatgaaga atatcgaatg atcgaagaag
     2521 atatcttagg aagaatgcct aattatacgg aaactggact gttttctgtt atgtggagcg
     2581 aacattgttc ctataaaaat tctaaaccgg ttctacgcaa atttcctact agtggacctc
     2641 atgtgttgca aggccctgga gaaggcgcag gcatcgtcga catcggtgat ggactagcag
     2701 ttgtcttcaa agcagaaagt cacaatcatc cttcagccgt ggagccttat gaaggagctg
     2761 cgacaggagt tggcggaatc atcagagata ttttcagcat gggggctcgt ccaattgcgt
     2821 tgctagattc attgaggttc ggcgaattag ataatccaag aacgaaatat ttactagaag
     2881 aagtagttgc aggtatcggc ggatacggca attgtatcgg cataccgact gtaggcggcg
     2941 aaattgcatt tgatccttgt tatgaaggaa acccattagt caatgcaatg tgcgtaggtt
     3001 tgattgaaca caaacatatc cagaaagggc aagccgctgg cgtcggtaat tcgatcatgt
     3061 atgtaggtgc aaaaacaggt cgcgacggta tccacggagc aacttttgcc tcagaagaat
     3121 ttaatcaaga agaagaacag caacgttctg ctgtacaagt aggcgatcct tttatggaaa
     3181 agctgctgct tgaagcgtgt ttggaattaa tcttgcatca ttcggattct ctaataggta
     3241 tacaggatat gggagcagca ggacttgttt catctagtgc ggaaatggct tcaaaagctg
     3301 gctcaggact tatattgaca ttagatgaag tcccacaaag agaaactggg atgacacctt
     3361 atgaaatgat gttatcggaa tcacaagaac ggatgttgat ttgtgttaaa tcaggagagg
     3421 aagaaaaaat ccaagaacta tttcagaagt atgatctaga tgcagtcact atcggtaaag
     3481 taacagacga cgggcaatat cggctatatc atcaaggaga agaagtagca aatctgccag
     3541 tcgatgcatt agctgaagat gcaccagttt atcataaaga aatgaaagaa ccagctcgaa
     3601 tcgtagaatt tcagcagtta gctccttatc agccagttat cgaagaacct ggacaagtat
     3661 tgcttgatct gctgcagcaa ccgacgattg cttcaaaacg ttcaatctac gaaacttatg
     3721 attcacaagt acaaaccaat acagttgtcc gtccaggaag cgatgctgct gtgatgaggg
     3781 ttagagggac gaataaagcg ttagctatga ccacagactg caacgcgcgc tatctgtatt
     3841 tggatccaaa aatcggagga caaatagcag tggcagaagc tgctagaaat attattgcta
     3901 gcggtggtaa gcccttggcg atcaccgact gcctgaacta tggttctcct gataaaccag
     3961 aagttttttg ggaattatcg acttcagctg acggaattgc tgctgcgtgt gaaacgttag
     4021 gaactcctgt tatttcagga aatgtctctt tatataatga aacggatggt caagcaatct
     4081 atccaacacc aatgattggt atggtcggat tgattgagga tcataaacat atcactactc
     4141 aggaattcaa aaaatcaggg gatctaatct atatattagg taagacgttt gcagattttg
     4201 atggcagtga attacaaaag atgcagcttg gaagaatcga aggtgtgatc cgaaactttg
     4261 atctatccat tgaaaagaga aaccaagagt tagtattgac agccatccaa aacggattga
     4321 ttgaaagtgc tcatgactgt tcagaaggtg gcttggcaat tgcactggca gaatcagctt
     4381 tcaaacatca gctagggata tctgtacagt ttgaattgtc ctctgctcaa ttatttgcag
     4441 aaactcaatc aagatttgtg ttgacagtcg caccggaaaa taagacacga ttcgaagaaa
     4501 tgatgggaga tgctgctgtt ttagcaggta aggtgacgga tgaagcgata atcgaaattt
     4561 cagcaactga cggtcagatc aaaatagaaa ctgcagtagc aagaaagtgc tgggaggatg
     4621 caatcgtatg tcttatgaag tgaagagttt aaatgaagaa tgcgggatct tcggtgtttg
     4681 gggtcatcca gacgccgcta gtgtggcata cttcgggctc catagtcttc agcatcgagg
     4741 acaagaaggt gcaggtatcg tgtccaatga tcgaggaaag cttaaggggc atcgagattt
     4801 ggggctgctt tctgaggtat tcaaagatca aagaaaattg cagcagttaa caggagaagc
     4861 tgcaatcgga catgtacgtt atgcaacagc aggcaatgga agtgtggaca atattcagcc
     4921 ttttctattc aaatttcatg atcagtcgat cggcttagcg cataatggta acttgatcaa
     4981 tgctcgttcc cttagaaaag agttagagga aaatggggcg atcttccatt ctaactccga
     5041 tacggagata ttgatgcatt tgatccgacg aagtgaagaa acagattttt taaataaatt
     5101 aaaaagtgct ttgaatgaag tcaaaggtgg ctttgcctat ttattaatga cagaaacggc
     5161 aatgattgcc gctttggacc caaatggttt tcgtccatta gcaatcggac aaatgaaaaa
     5221 cggagcatac gtgattgcct cggaaacttg tgcattagaa gttattgggg cacgttttat
     5281 aagagatgtc cagcctggtg agatagtgat catcaatgac gaaggaatcc agattgattg
     5341 ctttacgaag gacacgcagc tttctatttg ttcgatggaa tatatctatt ttgccagacc
     5401 agattcaaac atcgcaggga tcaatgtgca tactgcacgg aaaaatatgg gacggaattt
     5461 agcgaaagaa tcgccagtaa aagcagatat ggtcgttggc gtacctaatt cttctttgtc
     5521 agccgcaagc ggttatgcgg aagctagtgg aatcccttat gaaatcggat tagtaaaaaa
     5581 tcaatacatt gcccgaacat ttatccagcc aacgcctgag ctaagagagc aaggtgttcg
     5641 aatgaaatta tctgctgtac gaggagtagt ggaaggtaaa aaggtgatta tggtcgatga
     5701 ttcaattgtt cggggtacga caagcagacg gatcgtccat cttttgaaag aagcaggggc
     5761 aaaagaagtc catgtgagga ttgcttctcc tcctttgaaa tatccatgtt tttacgggat
     5821 tgatattcaa acgcgtaaag aactcattgc ggcaaatcac acgattgatg aaatcaaaga
     5881 atgtatcggt gcagattctt taggtttttt aagtgaagag ggtctgatcg aatcgatcgg
     5941 tctggaaaaa gatgctccgt attcaggatt gtgtatggct tatttcaacg gagattatcc
     6001 gacgccgtta tatgactatg aagaaaaata tcaggaatca ctaaaagaaa aagtatcgtt
     6061 cttttaaaag cagaccaaga agggagtata tgaattcaat ggcaaatgca tacgcaaaag
     6121 ctggcgtaga tgtcgaagct ggatatgaag tagtagaacg gatcaagaag catgtcaaaa
     6181 aaacggaacg tttaggtatg atgggcgcta taggaggatt cggcggttgt tttgatttat
     6241 cggtctttca attaaaagag ccagtccttg tctcggggac cgatggcgtg gggacgaaat
     6301 tagcagtggc aatcgaagca gacaaacacg atacaatcgg gatcgactgc gtagcgatgt
     6361 gtgtcaatga tatcttagca caaggcgcag agccgttata tttcttagac tacttagcaa
     6421 cggggaaaaa tgatccgtta cgtttggaaa atgtagtaaa aggtgtagca gatggatgtg
     6481 ttcaaggaaa tatggcgctg attggcggag aaacagctga aatgcctggt atgtactcag
     6541 gtaatgatta tgatctagcc ggatttgctg tagggatagc tgaaaaatct caattattga
     6601 caggagaaac gatcaaccca ggagatgtgt tgcttggaat agcatctagc gggattcatt
     6661 caaatgggta ctctcttgtt cgcaaaattt tctttgagca gcagcagttt tctttatcat
     6721 caaaactgcc agaattgaaa aaaacacttg gcgaagaatt gcttgagcca acgaaaatct
     6781 atgtttcttc cttgcttccg ctgatcaaag aaaagaaaat aaaaggagct gcacatatca
     6841 ctggtggagg gtttgtagaa aatatcccgc gaatgttacc agaatctatg gctgcacaaa
     6901 tcaaacttgg ctcatggccg attcttccaa tattcggctg tttacaaaaa tatggtgaaa
     6961 ttcctgagat ggagatgtat gaaatcttca atatgggcat cggtatggtc ctggcagtcc
     7021 aagaatcgaa agtaaaagaa atagtacacg aaattgagca agctggcgaa aaagtttatg
     7081 aaatcgggaa agtgatcgcc aaagaaaaac atcgtgtggt gtttatagga gaagaacgat
     7141 gagaatcgct gtttttgctt ctggaaacgg aagcaacttt caagcgctag ccgattatct
     7201 atcgaaaaaa ggattggaat cttcgattga ctggttgttt tgtgatcagc ctgaagcata
     7261 tgttttgaaa cgtgcaactg cgttgagtgt accggcagat tgtttttcac ctaaagaatt
     7321 tgattcaaaa aaagagtatg aagaagcaat tttgcataaa ttgaaagaaa aaaagatcga
     7381 tttgatcgta ttagctggat atatgcgaat cattggaccg gtattgctga aaaattatga
     7441 taaaagaatc atcaatatcc atccgtctct tttacctgcc ttccctggtt tgcatggcat
     7501 acgtgatgcc tttgaagctg gagtaaaaga aacgggtgtc acaattcatt atatcgacca
     7561 aggtgtagat actggaccaa tcatccggca ggaaaaagtg agaattgaac aggaggacac
     7621 gttcgattct ttagaagaaa aaatccatag agtagagcat cgaatctatc cagaagtgat
     7681 tagtgaaatt attgaaaatg gaggctatct gaaatgacaa gagcattgat cagtgtatca
     7741 gataaaactg ggattgtagc attcgcccaa ggtttgattg aacaaggagt agaaatcatt
     7801 tcaacaggag gaacaaagca tgcgttggat aaagctggga tcaaaacgct ttcgatcgaa
     7861 gaagtgacag ggtttcctga aatgatggat ggccgtgtca aaacacttca tcctaaaatc
     7921 catggtggtc ttttaggaag acgcgatctc cctagccata tggaggcaat ggaaacggaa
     7981 aatatccaac caatcgactt tgtttgtgtc aatttatatc ctttcaaaga aacgattatg
     8041 aaaccagatg tcgaaatagc agaagctatt gaaaacattg atatcggtgg tcctagtatg
     8101 ctccgtagtg cagcaaaaaa ccatgaattt gtcacctctg ttgttgatcc atctgactat
     8161 gaagaagtac tttcagaatt acgtcagtat gggcatactt cactttcttt cagacaaaaa
     8221 ctagcggcaa aagtctttcg tcatactgcg gcatatgatg cactgatcgc tcaatactta
     8281 acggattggg tggaagaaaa agaaccggaa aaattgacac ttacgtatga acgaaaacaa
     8341 acgcttcgtt acggtgaaaa tagccatcaa gccgctgcct tttatcagtc cgctcttctg
     8401 gaaaaatatt cgatcgcagc agcaaaacaa ctccatggga aagaactttc ttataataat
     8461 atccgagatg cagatgctgc gctacggatc atgaaggaat atgacgagcc aacggtagtc
     8521 gccttgaaac acatgaatcc ttgtggtatt gggacagcat ctacgatttt agaagcgtgg
     8581 gaagcagcgt atgaagcaga tcctgtttca atctttggtg ggatcatcgt tttgaatcga
     8641 gaagtagatc tgccaacagc agaacagatg cataagctgt ttctagaaat catcattgcc
     8701 ccttcttata cacaagaagc tttggaatta ctgcaaaaaa agaaaaacat ccgattactg
     8761 acagtagact ttgcgcagga agaaaatcaa aatcgagaag aaacggtctc agtcttaggt
     8821 ggacttcttg tacaagatca agatctggca atagaaaatg aagaagagtg gaaagtcgtg
     8881 acaaaacgta agccgactcc agcagaagca aaagcattag cgtttgcttg gagagctgtc
     8941 aaacatgtga aatctaatgc gatcgtactg gcaaacgaac gtcagacagt aggaatcgga
     9001 gccgggcaga tgaatcgagt cggttcagta aaaattgcga ttgaacaagc gcaagagaaa
     9061 atggaaggtg cagttttagc tagcgatgct tattttccaa tggatgattc ggttgaatat
     9121 gcagccaaac atggtataaa agcaatcatt cagccaggag gaagcatcaa agaccaagat
     9181 tctattgata tggcgaataa atacgatcta gcaatggtct ttactgatgt tcggcatttt
     9241 agacattaga gaggagtcgg ataaatgaac attttggtga tcggtgcagg tggtcgtgaa
     9301 catgcaataa gtaaaaaact tttagccagt ccgaaggtgg atacggtgta ttgtgcgcca
     9361 ggaaatccgg ggatgacaaa agatggtatc aattgtgtcg ctatcagtga gcgagatcat
     9421 tcagcgttaa tccattttgt taagaaagag gctattgatt ggagtatcgt tggtcctgaa
     9481 gttcctttgt taaatgggat cgtcgatgat tttatggcgg aaggattgaa aatcttcggt
     9541 ccgacaaaag cagcagctct gatcgaaggt tcgaaaagtt ttgctaaaca attaatggat
     9601 acttatcaaa tcccgacagc taaatccaga agttttgaat gttacgaaaa agcagcagcg
     9661 tatatcaaag aaaatggtgc gccaatcgta gtgaaagcgg acggcttagc agctgggaaa
     9721 ggtgtagtcg tggctaccac agtgaaggaa gcgctggatg cggcagaaca aatgttgaac
     9781 cagcatcgat ttggggatag tagcaaaaaa atcgtcgtag aagagttttt ggcaggagaa
     9841 gaattctccc ttttggcgtt tgtccgtaat accaaggtgt atccgatggt catttcgcaa
     9901 gatcataagc gggcatttga taacgataaa gggccaaata caggcggaat gggtgcttat
     9961 tcaccagtac cgcaaatttc aaaaaagatg attgaaaaag ctgtggaaga agttttaaaa
    10021 ccagcggctt tgggaatgaa agaactagga cgctctttca cgggtgtttt atatgcgggt
    10081 ttgattgcta cgaaggaagg accaaaagtg atcgaattca atgcgcgttt cggtgatcct
    10141 gaaacgcaag tcgttctttc tcggttgaag agtgactttg cgcaagtaat cgatgattta
    10201 ttagagaatc gtacagtaga gttaaagtgg cagcaagaag gatacaatgt aggcgttgtg
    10261 gttgcagctg ccggttaccc cgaagaatat gagacaggaa tggttctacc agattttctg
    10321 gaagaagagc tttctgttta ctatgctgga gtttcctcaa ataacggcaa actagttgga
    10381 gcaggaggac gtctttattt agtagaagca tacggtgaga cgatcaaaga agcacagaaa
    10441 aaaatttaca ccgcgttaat ggataaaacg acagatggaa cattttatcg tacagatatt
    10501 ggagaaaaag ctgccaatag cgaactgatc gtgaagtaaa tcagctgctt ccatttataa
    10561 aaaatacaac aaacataatc ggaagcgccg attttagtga agccttttca taaagagtgt
    10621 ggtacacttt tgttgtgtat ataaataagg aggagttcag atgaaaaaaa ttcaattagg
    10681 tacttctgat cagaaagcag ctgcagtgat cttaggctgt atgcgtatca acaatgcgga
    10741 agatccagta aaagtgattg agacagctta tgaaaacggc attgattttt ttgaccatgc
    10801 agatatttat ggaaacggtg aatgtgaaga aatctttgca gatgctctag caaaaacatc
    10861 aatcaaacga gaagatcttt ttattcaaac aaaatgtgga atcgttccag gtgtgatgtt
    10921 tgatttttct aaaaaacata tcattgaatc tgtagaaaaa agtttgaccc gtctgaaaat
    10981 ggattatgtg gatgctttac ttcttcatcg tccagataca ttggtagaac cagaggaagt
    11041 agctgaagcg tttgatgaat tggaacggtc aggaaaagtt cgttattttg gcgtcagcaa
    11101 tcaaaaacca atgcaaatcg aattgctgaa aaaatatgtt cgtcaaccat tagtagctaa
    11161 tcagctgcaa tttggcttga aacatactgg aatgatcgat caagggattc atgtcaatat
    11221 gacagatgaa gcaagtatcg atcatgacgg tagtgtactt gattattccc gattgcatga
    11281 tatgacgatc caagcatggt caccatacca gtatggattt tttgaaggtg tatttatcgg
    11341 gaacgaaaaa ttccctgaat taaaccaaac attagaagaa ctagcagcta aatatcaaac
    11401 gacaccaact ggcttggctt ctgcttggat tttacgccat ccagccaata tgcaagtgat
    11461 cgccggtacg atgaacgtag ggcgaatcaa ggaaatcgct caagcttcag aaattaatat
    11521 gtctcgggaa gattggtacg aattgtaccg tgctgctgga aacattttac cttaaagatt
    11581 gtcataagca ggtcaaaagg gctataaatt aaaaagacag aataacttga aagctgtttt
    11641 cagcttcgag atattctgtc tttttttatt gcaaatggaa agagtatcat tgtacggatt
    11701 tcgtttatta gttatttttg tttttaagga aaagctgtgt ccgatattct tttggagaaa
    11761 tcccttgttt tttcttaaat aaataactga aatagttagg gtcattataa ccaatttcaa
    11821 aagcaatatc tgaaatacga tagtctgatt gctgcaataa tttttttgct aattcgattc
    11881 tttgttctgt cagataatcg atgaatgttt ggttaaacga ttgagaaaaa atcgtactga
    11941 aatgagaggg acttaatgca acttgttgag cgacccaagt taaggacata tctggatcgg
    12001 taaaattttc tttgataaaa tccaatgcat ggttcaaaat tggctgatat ttgttccttg
    12061 aaggctgtga gggcagagca gttaagaaag aaatgaacat ataaactgtc gaacggtaaa
    12121 gcgagtcgtc ggcgctgatt gctaagcgtt gactggtgga tgtgcaatga accatttctt
    12181 gcgggatttt cttttctttc aggcagacat gctggagtag cttagtcaag acaaataaac
    12241 gatataatcg tgttcgagtt ggtgtgcctt gtggtttcgt caagtgttcg atgtacttag
    12301 atacttcgtt tttcgataat gaagacaaat caagtgagag gtcaaagtaa aagacagaat
    12361 caactggaag tttcgcttct tgaatcaaat cctcatagct gataatttgt tctttaaggg
    12421 aactggcggt ttcaagtatc atctgcgtga tctcaaaaga tgcaggtaat tcgctgattc
    12481 tttctgcgac aggaccaatg gcgacagaaa aattattttt ttgtcccttt tctaattcat
    12541 ggaccaacgt ttgggctacc tgataactgg tctcgatcac attttcttca agagaatcaa
    12601 ctattaaaaa tttgatgaat cgagaggaaa cagcagagaa gatcacttgt tgattctccc
    12661 taaataaaaa cttcaaataa tcactgagat gagcgtaatc ttcaaagtct gtactgactt
    12721 ggtttgctgc taataatacg gtcatttttt tccctgctaa agagcgattg aaagattcag
    12781 caagtttcaa tgtttcactg atcgtaagtg agcctttgaa caaaccgttc aagaaatgat
    12841 tttttttcaa ttcgaaaaca agatcagaag aagtgtgcgt ttctttttgc tgcaaatcta
    12901 aagcagttac tgctttttct attgcttgtt tcaattcgct acttttaatc ggtttaagca
    12961 gataatcatc tgcctgtacc tggattgctc ctttcatata atcgaaatcg tcgaatccac
    13021 taataaatat gagacgagtc caaggaagta gtttccttgc ttcttttgaa aaagtcaacc
    13081 cgtccatgaa aggcatttgg atatcagtca gaatgatgtc gggctgtaag tcgataattg
    13141 aagacagtgc catctcacca tctccagctt cgccgacata agtgattgga taataagaac
    13201 caaggacagt tatttgttcc cgcaagttat tgcgaatgag gtattcgtct tcgatgataa
    13261 aaactttata catgtttgtt tcctccaatt gttttgggag atagagggat catcagtgtg
    13321 acagttgttc cttctcggta tttgctgtca atcgtgatag gtttttgatc atttccgtaa
    13381 taaagaagga gacgcttgtt tacgttgtaa agtccgtagc cgatactgaa atctgaatcg
    13441 atccctttgg ctaactcttt acgtatttct gccagttttt ctgcagggat gccaatcccg
    13501 ttgtctataa ctttgaattg gatcatctca tcaattttgc atgtggtaat acgaataaat
    13561 cctttgtgac ggacgtactt cgttccatgg tatacagcat tttcaatcaa tggctgcaag
    13621 atcattttta aaatagaaac aggaaaaagt gtttctggta tatcgatctt atagtcaagc
    13681 atatggccgt atcttatttt taagatgact agataatcat tgatatggct aatttctttt
    13741 tcaagaggaa tccagtcttg tcctttgctt aaagacgtac gaaaaaagcc ggaaagtgca
    13801 tgggtcatag tcagagcttc ttcaaagcag tcttgttcga tcaaagaaat aatggcatcc
    13861 aaactgttat aaataaaatg gggagtaatc tgagcttgca atacacgaac ttcactttgt
    13921 gctaaatggt attgtttcaa agcgttctcc cgtaaagact ggtttagatc ttccgccatt
    13981 ttattcatgc tagcggtaag tgtttgtaat tccagtgttt ccggcagggt taaacgaaag
    14041 ccaaggttcc ctgaagaaag ttgttctgac atctcgatca gctgattgat cggttcttgg
    14101 acctttctct ctaaaaagcg acgattcttt ttcgcataga aaaaaatggt actaagaact
    14161 ccaagttcca ctattgttaa tagaatgagc gagcggacaa gtgtcgtatt ttttttgctt
    14221 gctaagtcga tctccacacg aacaaaatct tgtaagatat ctgacagcag ttgagtgaca
    14281 gaatctacct gattgatgat ctcttcattg gtatccataa aatcttttgc caagatatta
    14341 ttgatcagct cgttttgata atcttccagt gtatcgatcg tacgtagcga tacatctaac
    14401 gtactaattt ctttaagtgt atttgtatta tttttgatct ctcgaatatc attcctaagt
    14461 tcttctagga tattttcctc attgaactca tctacggtta cttggccaga aatcaagtcc
    14521 cacatacttt ccaaaacttt ttgatcaacc ttcaaagcaa ttgcatctgc tttttggata
    14581 tttgcgatcg tctgttgata aatcaaaagc tgttgcgaat ataacagtat gctcagtagc
    14641 aaagggataa cagcaaatag aagcatggct ttgtttgctt gggcaaaaat ctgttttatg
    14701 cttaaatttt ttgtcatgat acttctccag tcaataattt ctggttggga tgttagctat
    14761 attctgctgg gaaaagacag tctcggaaat aaaaatatct ttaggtaatg tttttcctgt
    14821 ttgaatattt ccaaaataac gagtaacggt attggctaca taccagccga catcaggttt
    14881 acactcgact acacaattga cgattcctga gcgtagcttc tcgatcatat cttcttgtcc
    14941 atcaatagtt acaatgatca aatcttctcc aggtttgatt gatgtttctt ttatcgcagc
    15001 taaagcaccg tgagtcattt catcactatg gctgtataat acatcgattt cggataaatc
    15061 atttgtttct aaatatcgtt tcatctggtc ttttcctttc atccgaataa aatcaccgac
    15121 aattcggtga acaatagtca tcggaggttt atggtcgatg gttccatctt tttttagggt
    15181 tggtttacga ttgattgatt ccaaaaatcc ttcggagcgt agcttggtcg gtgtggagtt
    15241 ctctgaacca gcaagttcta ggattctgat ttcctgtttc tttgaatttg tgaagtgatt
    15301 gctgacaaat aaacccgccc gatttccttc tgctttgaaa ctggggccaa tgtgggtgac
    15361 gaaaagctcg ggatcattcg tttgaatatg tctgtcgaca agtatgacag ggatccctgc
    15421 tcgctttgct tcttttaata cagagtccca cccggattct tgcaaaggag taaaaatgat
    15481 catatccact ttataggcaa tgaacgtccg tatatcttgg atttgccgtt cctgattcat
    15541 gtagccattt cggtagagaa cttggtaatc ttctttttca agcgcagtga taattgattc
    15601 agtatgcttt ttccgccagc tactctccgt tcctgattgc gaaaaaccaa cgactagtgg
    15661 gtcaggtgct tcctttgtat taggtgtaca ccccatcatt tggtaagcga ttacaacaag
    15721 ggctaaaaaa aataaaacac gtttcacttt aaatcactcc atctggattt gttagtacta
    15781 tcttatcaga taaaagggaa aatcaaagtc aaaaggaatc aatcgaaaaa aatccaagaa
    15841 acttaaaaaa atccaagaca aaaaaagtac acctaaaaaa tttaaagtaa atcccataaa
    15901 aaaatcaatg ttaacgcttt ctttattagc tatactcggt gtatcaattg aaatggggga
    15961 taaaaaatga aaaacaaatt tagaaagatt gttgggacta tcgctatttt gaccgcaagc
    16021 attctattaa gtgcgtgtgg caattcagga tctgcagatg atagtacggg gtatgtagga
    16081 atcgctatgc cgaccaaatc agcagaaaga tggatcgctg atgggaacaa catggtctcg
    16141 gaattagaaa aactgggtta taaaacagat cttcaatatg gagaagataa agtagaaaat
    16201 caagtagcac aaatagaaaa tatgattaca aaaggggtag atacacttgt gattgcttct
    16261 atcgatggtt cggctttaac tgatgtgtta gctaaagcaa aagaagcaga tatcaaggtg
    16321 atcgcctatg atcgtttact gatgaattca gaaaatgtcg attattacgc gacttttgat
    16381 aattttggag taggtgtatc gcaagcagct tatattgaag agcacttagg attgaaagaa
    16441 ggaaaaggac cattcacgat tgaattattt ggtggctcgc ctgacgacaa caacgcacta
    16501 atcaattaca acggagtgat gtctgtttta caaccatata tggacaacgg tcagttggtc
    16561 gtgccatctg gacagacgag tttcagtcaa atcgctacgc ttcgctggga tggttctacg
    16621 gcgcaagcaa ggatggataa tctgttaagc gcaaattata ctgaccaaac attggatgct
    16681 gttttgtcgc catatgatcc aataagttta ggaatcattt cgtcattaaa aggcgtgggg
    16741 tatgggagtg aaagtaaacc tttacctgtg attactggac aagatgcgac agttgctggc
    16801 gttaaatcga tcattgccgg ggaacaaaca caaacgatct ttaaagacac acgtatctta
    16861 gcaaaaaata cgattgaaat gatcaaagca atcagtgatg gagaagaggt tccggtcaat
    16921 gatactgaaa cttatgataa tggggtgaaa actgtcccta cgtatttagc aaatacagta
    16981 tctgtcgata aagataatta tcaagcagag ctgatcgaca ccgattatta taaagaatcc
    17041 gatctgaaaa attaagagga accaaacaag gaactaaaga gatctaagtc agagagagga
    17101 taagaattat ggcggattgt attttaaaaa tggcagatat caccaaaaaa ttttctggaa
    17161 tccgagcgtt agattgcgtg aatctgatga ttgaacgtgg ggaaatccat gcattgtgcg
    17221 gagaaaacgg agcgggaaaa tcaacattga tgaatgtctt gagcggcttg tatccatatg
    17281 gctcctatga cggggaaatc ttttatgatg gaaagctgtg tcaatttaaa gatttgaaag
    17341 atagtgaaga aaaaggcatc gtcatcattc atcaagaatt agcactaagt ccttatcttt
    17401 caataaaaga gaatattttt ctcggaaatg aacaagcaga aagaggcgtg attgattggg
    17461 aactgacaga aaagaaaaca tatgaactgc tgaataaagt cggtttgtct atcgacccga
    17521 atcttctagt atcccagatt ggcgtagggc aacagcaact agttgaaata gctaaagcat
    17581 tatcaaaatc cgtccgtctg ttgattttgg atgagcctac cgctgcattg aatgaagaag
    17641 aaagcgcgaa tttgctgaga ttgatccgag agttgaaaga gcaaggtgta acctccatca
    17701 ttatttcaca taagctgaat gaaatcgtgg atatcgcaga tcgaatcacc attttacggg
    17761 atggacagac gattgagaca ctagaaaatg aaatgatcag cgaagagcat attattcgcg
    17821 gaatggtggg cagagattta gttgatcgtt atcctgaaag aaaaccggat attggagaag
    17881 tttattttaa agtagaagac tggacggtct atcaccctct tgatcacgag cgaatcataa
    17941 acgaccacat caacttgcat ttgaaaaaag gagagattgt aggaatagct ggactgatgg
    18001 gagcgggcag aactgaattc gctatgagtc tatttggaca ttcttatgga agcaagatat
    18061 ccggacgtat attaaaggaa ggggcagaga tatcagttaa gaccgttcct tcagccattg
    18121 caaacggact cgcttatgtc tcggaggacc gaaaatcttt aggactgaat ctgctgatgg
    18181 atattcggga aaacgtgacg ctgagcagtt tggataaaat aagtcaaaaa ggagtattag
    18241 ataaagaaaa agaagtaact gaggcagaaa atttccggaa aaagatgcgt ataaaaacaa
    18301 actccatcca tcaaattgtc agtagtctta gtggtgggaa tcaacaaaaa gtcgttttat
    18361 ccaagtggct gatgacacaa cccgatattc tttttttgga tgagccaacc cgtgggatag
    18421 atgttggggc aaaatatgag atctacacga ttatcgaaga aatggcagca aatggcaaag
    18481 ctgtctgtct tatctcttct gaacttcctg aaatattagg gatgtgtgat cgaatctata
    18541 cgatgaacga aggacgtatt acaggagaag tctcgcgaga agatgcagat caggaagtct
    18601 tgatgaaatt aatgacgaaa gaagaggtgg gttaagttgg aacaggcaaa aaatcttacg
    18661 gataaaaaag agaaaaaact aaatttgaaa agtagagcag ctgatctttt tggtcgctac
    18721 agcatggtga tcattttagc gggactactt attgcgtttc aattgatgac ggatggtatt
    18781 ttctggcgtc cattgaatat aactaacctt gttctgcaaa atagccatat attagtacta
    18841 gctgcaggga tgttattagt tgtgctctta ggtcatgtgg atttgtcggt agggtcagtg
    18901 atggcgtttg ttggtgcaat tgcgggcatg atgatggtca atcgccaaat gaacccgtgg
    18961 atgacagtta tcgcatgtct tgcagtaggc gggctgatcg gcgcatggca aggtttttgg
    19021 gtagcttatg cagggatacc ggcgtttatc gtgactttag caggattgct gatgtttcgt
    19081 ggactgacac aagttgttct aggaggccaa tctctagcac cttttccagc tgttttccaa
    19141 aaaatgtcta cgggttattt accagactta agcgaaggaa gcagccttca cttcttgaca
    19201 ttgattttag gaatgatcat cacgatcgtg ttagttgttg gtcaatggcg aacaagaaat
    19261 cgtcggaaaa atcatttatt tgaagtggaa tctccaacag ctttcttggt aaaggcggta
    19321 tttacagcag tcgttgtact aggaataact tatatctttg cctcttatca agggtatccg
    19381 attattttga tcattcttgg tttgatcgtt gcagcatatg ggtttttgac aaataaaaca
    19441 gtagcaggtc gacagattta tgcgacgggc ggaaatcgaa aagcggctga actatcaggg
    19501 atcaaaacaa agcgaatcac gttctgggta ttcgtcaaca tgggagtcat ggcagcttta
    19561 gctggattag ttttagctgc tcgattgaat gcggcaacac ctcaagcagg tacatcgatg
    19621 gaactggatg caatggcggc agtatatttt ggtggtgctt cgacttccgg cggcattgga
    19681 acaatcatgg gtgcgattgt cggtggcttg gtcatgggtg tattgaacaa tggcatgtcg
    19741 attttaggcg tcggggtaga ctggcagcag gcaatcaaag gattgatctt gcttttagcc
    19801 gttgtgctag acttgtataa taagaaaaaa cgaacaacgt aggagaacgc cggttattca
    19861 gaaaaaagac tgtgacaaga catttgtcac agtctttttt tcgctaaaag cgaacattca
    19921 ttgtttcgtt tgtatagact aaaaataata tatgtttttt taccattcgt ataaattctc
    19981 tttttgctct tgattttttt gcttaattga gttaaattac atagggcgct aaaaaaagcc
    20041 ttgattaaat taataatgtt cgtgttttgc tggatgtgaa catcaggagg ataatgtaat
    20101 gaaagtattt gattacgaag atattcaatt aattcctaat aaatgtatcg taaatagccg
    20161 ttctgaatgt gatacaacgg tcacattagg taaacataca ttcaaaatgc cagtagtgcc
    20221 tgccaacatg cagacgatta ttgatgaaac aatcgcagaa ttcttagcgg aaaatggtta
    20281 tttctatatc atgcatcggt ttgatgaagc agctcgaatt ccgtttatca aaaaaatgaa
    20341 aaagcgtgga ttgattacct cgatcagtgt tggcgtcaag aaagaggaat attcctttat
    20401 agagaagttg gcagaagaat cgctaaatcc tgattatatc actatcgaca tcgcgcatgg
    20461 acatgctaac tcagttattg atatgattca gcatattaaa aaatatttgc ctgaaacttt
    20521 tgtgattgcc ggtaatgttg gtacaccgga agccgtccgt gaattggaaa atgcgggcgc
    20581 agatgcaaca aaagtcggga ttggtccagg aaaagtatgt attacaaaaa tcaagacagg
    20641 ctttgggact ggaggctggc aactggcagc tcttagatgg tgtgcgaaag cagctcgcaa
    20701 gccgatcatc gctgacggtg ggatcagaac acatggcgat attgcaaaat ctgtccgttt
    20761 tggtgcgaca atggtcatga ttggttcatt gtttgccggt cacgaggaat ctcctggcga
    20821 aacaaaagtc gaaaatggaa tcgtgtataa agaatacttt ggttctgctt cagaattcca
    20881 aaaaggcgaa aaacgaaatg ttgaaggaaa gaaaatctgg atccaacaca aaggatcttt
    20941 gaaagataca ctagtggaaa tgcaacaaga ccttcaatca tctatttctt atgctggagg
    21001 aagagatctg gaagccattc gaaaagttga ctatgtcatc gtgaaaaatt cgatttttaa
    21061 tggagacaca atctaaaaaa taaataaaat attaggatgt tgtgaaaaag ttgtcctgca
    21121 ttaagtaata agaacagcca aacaaaaata gttctttata tgttttgttt ggctggaatt
    21181 attatcgcag atacaagctt ttgaacatca ttattcagaa taagggactg tgataagatt
    21241 tttgtcacag tcccttatgt tttgcaaaaa aagtttttct tttttctcgt aaattcggta
    21301 aaatcaaaag aaaaaataga caatagaaaa gagaagctta tgtgggaaaa agtagagaaa
    21361 aaacaaggac cgatttatcg tcaaattatg gaacagatta tgagagaaat cgaaaacgga
    21421 aggatcaatc ctggaagtca acttgaatca gaacgaaaac tagggcaact ttttggtgtg
    21481 aatcgttcca ccgttgtcca tgcattggaa gagcttaggg agcttggggt actaacgagc
    21541 aaacgtggca gcggatggtt tgttaatcag actgaatggg ggaaattcgc tgttccaaga
    21601 atcgattggc ggcaaatgat ctctcctcgt tatgagcaga cggactggta tgagcaaaaa
    21661 ataagagaag caaagcagat ccaaaaaaca tcgtttcttg atttatacgc tagcgagatg
    21721 ccagatgagc ttttgccgaa ttttgagttt ccttcttatt ctcttgaaga aatcttagcg
    21781 gaagaaaaag aaatggatct tttaggctat actccgttac gtaacaaaat caaacggtat
    21841 ttggaaagta aatttgaatt ggcattttcc cccaaccagc ttcttgtgac tggtggcggt
    21901 cagcaagcaa tctttttgat tttacaaacg attctttcag ctggagaggg gatagctgta
    21961 gagtcacctt ctttttttta ccgattacct cttttcaaag cttcaggaac gcgtttattt
    22021 gggataccga tggatgaaga agggatcgac ttagaaaaac tgaaagaatc gatccataaa
    22081 aataaattga aagcagtgct tatcaacccg aattttcaaa accctacagg aaaagtgatg
    22141 agtcaaaaac gacgagaaaa gctagtagaa ttgtgtcgac agtatcggct tccaattatt
    22201 gaagacgatg tatttacgga tctttcattt ctaaaccaag aagaagtcct tcctatacga
    22261 acgattgatc cggataatgt gttatacgtc ggttcgttat ctagggtttt aggaaaaaca
    22321 acgaaaatcg gttgggtgat aggacctgag acttttatct cgcaactagc tcaagcgcaa
    22381 gaaatgatgg agttttcgat gaatatcctt acacaaatca cagtggctaa tgtatttaat
    22441 gaagcaattg atttgaaaat gcaagatgta agaaaaaagt tgaaagaaaa aagccgactg
    22501 ataagcgctt ggggagattc acaatcgttt ttcaagcttc attcaatttt aggtggttac
    22561 tatgcctgga ttacttggga tgggaaaaaa ctagaccccg aactagcaga aaaagtagta
    22621 gatatgggtc ttggaattgc accaagtcta ctttttgggc aagatataaa tggaatcaga
    22681 atcaattaca gtaggctgga tgaaaaccaa ataccgttgt tttattcaaa gatgaaaatt
    22741 ctagaaaagt ggttaacaga ataatttcac aaagtaaata gattaaagaa tataacagct
    22801 tggatttaaa tttcaagctg tttctttttt ttcggaaaaa gaatacgata taaagaaact
    22861 aagaaaaaac cattatttgt acgtccgttc acgatgtgta aataaaataa atgtttgcaa
    22921 caaaactgta taacaccaac gtttttaaat agaaacagat ggttgtaagt ttgattagaa
    22981 aatagaaaaa atgcagatga aatataaaac gctttcctta ttgtgatttt attcactaat
    23041 gctgttaata tgcggattgg cataatttcc tttcatcgtg aaaatttgtg cttttagctt
    23101 gtatttctca taaatccatg ataatttatt aatgaagacg gttaaatagt gatacagttt
    23161 tattcactgt ttcaatcgca gaatgaagag attttcttat agatgagaga ggaatgtgtg
    23221 acaaatggca aacaaaaaag caccgatcga cttccaagca ctgctagatg aagtcaatgc
    23281 agatttccca gtatatcaag cacttgatca agatggaaac gtagttaaca aagatttagt
    23341 acctgattta tccgatgatg aactcgttga attaatgact catatggtat ggtctcgtgt
    23401 attagaccaa cgttcaacag cgctgaaccg ccaaggacgc ctaggctttt ttgcaccaac
    23461 tgctggacaa gaggcaagtc agctggctag tgcttacgca tttgataaag aagatgttct
    23521 tcttccaggt tatcgggatg tacctcaact agtaaaacat ggtttacctt tatctcaagc
    23581 ttttttatgg tctcgaggac atgctgcagg taattcttat ccggaagaat tgaaagctct
    23641 accaccacaa attatcatcg gtgcacaata tgtacaagca gccggtgttg cattaggttt
    23701 gaagaaacga aacaagaaaa atgtcgtctt cacttatact ggtgatggcg gttcatcaca
    23761 aggtgatttt tacgaagcaa tcaatttcgc tggcgcttac catgcaaatg ccgtatttta
    23821 tatccaaaac aacgggtatg cgatctctac acctcgtgaa aaacaaactg cagcaaaaac
    23881 acttgcacaa aaagctgtcg cagctgggat tcctggtatt caagtcgatg gaatggatcc
    23941 gcttgcagta tatactgtat ctaaaatggc acgggaatgg gcgatcagtg gaaatggacc
    24001 agtcctaatc gaaacactga cttatcgtta tggaccacat acactatctg gtgacgatcc
    24061 aacccgctac cgtacaaaag acacagatga cgattggcag aaaaaagatc cattgatccg
    24121 cttccgtaaa tatttgacgg aaaaaggact ttggtctgaa gaaaaagaag aacaagtcat
    24181 cgaagcaact aaagaagaaa tcaaagcagc tattgctgaa gccgacaaag taccaaaaca
    24241 aaaggtttca gatttcttga aaaacatgtt cgaagtatct ccacaatcaa tcaaagaaca
    24301 aattgcaatt tatgaagcga aggagtcgaa ataatcatgg cacaaaaaac aatgatccaa
    24361 gcaatcacag atgccttagc acttgaacta gaaaatgacg agaatgtcgt tgtttttggt
    24421 gaagatgttg ggaaaaacgg aggagttttc cgggcaactg aaggattgca ggaaaagttc
    24481 ggagaagacc gagtattcga tactccttta gctgaatctg gaatcgcagg attgagtttc
    24541 ggtcttgcgt tagaaggatt tcgtccagtt cctgaaatcc aattctttgg ttttattttc
    24601 gaagcaatgg acgaagtagt agctcaaatg gctcgtacaa gatatcgaat gagcggcact
    24661 agaaatctac ccatcacaat tcgttcgcca tttggtggcg gtgttcatac accagaattg
    24721 cattcggata atttagaagg tttgatcgct cagtctcctg gtattcgagt agtgattcct
    24781 tccaaccctt atgatgcaaa aggactattg atttcttcta ttagaagtaa cgatccggtt
    24841 gttttcctag aacacatgaa actatatcgc tcattccgag aagaagtgcc ggatgaagct
    24901 tacgaagttc ctttggataa agcagcagtt actcgtgagg gaacagatgt atctattatc
    24961 acatacggag caatggtgcg tgaagcaatc aaagcagcag acaatcttgc aaaagaaaat
    25021 atatctgttg aaatcattga tcttcgtaca gttgcgccat tagatgtaga aacgatcatt
    25081 caatccgtgg aaaaaactgg tcgcgtagtt gttgtccaag aagcacaacg acaagcgggc
    25141 gttgccgcgc aagtagtttc tgagatctca gaacgcgcta tcctttcatt agaagcccca
    25201 atcggacgag tttctgcacc tgatacagtc ttcccatttg gacaagcaga aaatgtctgg
    25261 ttgccaaatg caaaagatat cgaagacaaa gtaaaagaaa tcgcggaatt ttaagaaaag
    25321 aagggacgaa acaaagtcat ggcttatcaa tttaaattgc cggatatcgg tgaaggaatc
    25381 gcagaaggtg aaatcgtcaa atggttcgtc aaaccaggag atacgatcaa tgaagatgat
    25441 acattactag aagttcaaaa tgacaaatca gtagaagaaa tcccgtcacc tgttacagga
    25501 acggttaaaa atgtgattgt tccagaaggt accgtagcaa atgttgggga tgtattagta
    25561 gaaatcgatg caccaggaca cgaagacaat gaaggggaca gtggtgtagc cgcagaatcc
    25621 caaactccag ctaaaccggc tgctgaaccc actgttgata cagaatcagc tggatcgtca
    25681 agcgaaggag tcttccaatt taagttaccg gatatcggtg aaggaatcgc agaaggtgaa
    25741 atcgtcaaat ggttcgtcaa accaggagat acgatcaatg aagatgatac attactagaa
    25801 gttcaaaatg acaaatcagt agaagaaatt ccgtcacctg tcacagggac agttaaaaac
    25861 gtgattgttc cagaaggcac tgtagcaaat gttggggatg tattagtaga aatcgatgct
    25921 cctggacaca atagtgcacc gtcaactagt gcgccatcag ctgaagcacc aaaagaaaaa
    25981 gtggaaacat caggttcagc aagtgtcgtt gaagctgccg atccaaataa acgtgtattg
    26041 gctatgccat ctgttcgtca atttgcccgt gaaaaagatg tagatatctc acaagtaact
    26101 gcaactggaa aaggtggcag agtaacaaaa gaggacatcg aaaacttctt ggcaggtggt
    26161 ccaagcagtg caccagcgaa atcagaagcg ccagaagcgg cagcaccgaa agaagcagct
    26221 cctgcagcag aaagcaaacc agctgcacca gcaaaaccat tcaagtccaa cttaggagac
    26281 ttggaagaac gtgtagcaat gacgccaaca cgtaaagcta tcgctaaagc aatggtcaac
    26341 agtaagcata cagctccaca cgtgacattg catgatgaag tagaagtgtc taaactatgg
    26401 gataatcgga aacgatttaa agaagttgct gctgcaaatg gtacgaaact tactttcttg
    26461 ccatatgtcg tgaaagcttt aacagcgact gttaagaaat acccagtatt gaatgcatct
    26521 atcgacgatg caaaccaaga aatcgtttat aaacattact acaatatcgg tattgcaact
    26581 gatacggatc acggactata tgtaccaaat gtgaaagatg cagaccgcaa aggaatgttt
    26641 gctattgcag acgaaatcaa tgagaaagca aaattagctc atgacggcaa actatctgca
    26701 gaagatatgc gcaatggaac aattacgatc agcaatatcg gatctgtagg tggcggttgg
    26761 tttacaccag tcatcaacta tccagaagta gctattttag gtgtaggaac gattgcacaa
    26821 caaccaatcg taaatgctga aggcgaaatc gttgtcggtc gtgtgatgaa actgtcatta
    26881 agtttcgatc accgtatcgt agatggagca actgcgcaac aagcaatgaa taatatcaaa
    26941 cgtcttttag ctgatccaga gctattaatg atggaaggat gataaacaaa tggtagttgg
    27001 agattttgct gtagaattag atacagttgt aattggtgcg ggacctggtg gctatgtagc
    27061 tgccatccgc gctgctgaaa tgggacaaaa agtagcaatc attgaaagag agtatattgg
    27121 cggtgtttgt ttgaatgtcg gctgtattcc ttcaaaagca ctgatagctg caggacacca
    27181 ttatcaagag tcactagatt ctgaaatgtt tggagtaact agtgaaaacg tcaaactaga
    27241 ttttgcaaaa acacaagaat ggaaagaaaa caaagttgtc catacgttga cttctggtgt
    27301 tggtttccta ttaaaaaaac ataaggttga aacaatcgaa ggagaagcgt tcttcgtaga
    27361 tgatcacaca ctacgcgtca ttcatccaga ttcagctcaa acttattcgt tcaataacgc
    27421 aatcatcgca acaggttccc gtccaatcga gattccagga tttaaattcg gaggacgtgt
    27481 gttagattct actggcggat tagcattgaa agaagtacct aagaaatttg tgatcatcgg
    27541 tggcggtgtg attggtgccg aattgggcgg agcgtacgca aacttaggag cagaagtaac
    27601 gattcttgaa ggctcaccac aaattttacc aacttacgaa aaagatctag taaaattagt
    27661 agaagatgat ttcaagaaaa aaggcgtaac agtcgtaacg aatgcaatgg cgaaagaagc
    27721 agtcgataac ggtgacagcg tgacagtgaa atatgcagtg gacgggaaag aagaatccgt
    27781 tactgctgat tatgtgatgg tcactgtagg tcgtcgtccg aatacagatg atatgggctt
    27841 agaacaagcg ggtgtcgaag taggagaacg aggattgatc acggtggata aacaaggacg
    27901 tacgaacgta cctaacatct atgccatcgg tgatatcgtt ccaggggcgg cattagcaca
    27961 caaagccagt tatgaagcaa aaatcgctgc tgaagcaatc tctggcaaaa aagtagctgt
    28021 agattataaa gcaatgccgg cagtagcctt cactgatcct gaattggctt ctgtaggtat
    28081 gacgatcaaa gaagcaaaag atgctggtat cgaagcaaaa gcatataaat tcccattttc
    28141 agggaacggt cgggcattat cgcttggtaa aacagaagga ttcatccgtc tagttacgac
    28201 gatcgaagat aacgtgctta ttggcgcgca aatcggtgga gtcggcgcaa gtgatatggt
    28261 ctctgaatta gctttagcaa tcgaatcagg aatgaatgct gaagatatcg ccttgacgat
    28321 tcatcctcat ccatctcttg gcgaaatcgt catggatgct tcggaattag cattaggttt
    28381 accaatccat atttgatttg aataatacag gcgaaacgca actgaaaaat cagttgcgtt
    28441 ttgtttttta gaattatcaa taatattatt atgtaaactt aaaaatatga caacttcttg
    28501 gtttattacc acttcctatg ctacactgaa gaggaatatg aaataggaga gttgaagatg
    28561 caagaatatc agtatccact tgatttagat tggacaacag acgaaatggt cattgtaatg
    28621 aagatgtggg aagatctgga acgtgcgaat gaaaaaggga taaacaatga agcttttttg
    28681 aagacttatc agcagtttaa aactgttgtc aaatccattg gtgaggaaaa acgattggga
    28741 cgggaatttg aaaaagcttc cggttattct ttatatcgta cagtgcagca agcaaaaaaa
    28801 aatccaaaca aaactttgag aatgaacggg tgagataaat ggaacagatg attgatcata
    28861 tcaagtcctg gcttgaagaa gctggtgaga aaatcaaatc ttctcaacaa acattaacaa
    28921 tctcgcaaaa atcaaatcga acggatctag taacaaatgt cgatcgaaac atccagaatt
    28981 ttctaatcga aaaaatccat tcctttgatc cagaggcgaa aatattggca gaagaagaag
    29041 ggtgtaatca attatcggat ctcgatggaa gagtctttat catcgatcct attgatggca
    29101 ccttgaattt tgtgattgaa ggggaaaatt tttgtattat gctcgctgtt tatgaatccg
    29161 gcgttggaaa gcttggtttc atttatgacg tgatgagaaa tgaacttttt tggggtggaa
    29221 aaggaatagg cgtgtataaa aatgatgagc cattgcctag accagcaaat aaatccttat
    29281 cggaaggctt acttggtgtg aatagttatc ttttcggtca taataaatat ggaatccgag
    29341 aaattgcgga aagcagcatg gggacacgta tgtacggatg cgctggtctt gaactagtgg
    29401 caatcttgaa aggaaaccac attgcttata tttcaaacct tagcccttgg gattatgcag
    29461 cgggaaatgt cttattggaa gagtttggta tggtaacaag cggtcttttt ggtactcctt
    29521 tgacatttga aaaaagggaa tactatttag cagggacttc ttgtgcatat gcagaaatcg
    29581 cagacctttt gaaaaaagaa ggctgaaaaa aaggtagaaa tcattcacaa aaatgataaa
    29641 aacgagcaaa agattaattt tctcgaaaaa atgaaaacat tttactatat ttcatgaaaa
    29701 aagtctgcta taattagcag tcgagtaaaa tttgccctgt cataaagaac caataaaaaa
    29761 ggagttagtt acattgaatt atagaaacga tatccgtaac gtcgcaatta ttgcccacgt
    29821 tgaccacgga aaaacaacat tagttgatga actattaaaa caatcagata cattagacgc
    29881 acatacgcaa ttgcaagaac gtgcgatgga ctcaaatgcg ctagaaaaag aacgtggtat
    29941 cacgatttta gccaaaaaca cagctgtaga ctataaaggt attcgcgtaa acatcatgga
    30001 tactccagga cacgcggact tcggtggcga agtagaacgg atcatgaaaa tggttgacgg
    30061 cgttgtgttg gtcgtagatg cgtatgaagg aacaatgcct caaacacgtt ttgtattgaa
    30121 aaaagcactg gaacaacata tcacaccaat cgttgtcgta aacaagattg acaaaccttc
    30181 tgctcgtcct gagcatgtcg tagatgaagt tcttgaacta ttcatcgaat taggagcaga
    30241 tgatgatcag ttagactttc ctgtgattta tgcatctgca ctaaatggta cgtcaagctt
    30301 gtcagatgat ccagcagatc aagaaccaac catggcacct atttttgata caattattga
    30361 aaaaatccct gctcctgtcg ataacagcga cgaaccatta caattccaag tttcattact
    30421 tgactacaac gattatgtag gtcgtatcgg aatcggacgt gtatttagag gaacaatcaa
    30481 agtaggagac caagtagcat taattaaatt agacggaaca gttaagaaat tccgtgtaac
    30541 gaaattattt ggtttctttg gactaaaacg tctagagatt caagaagcaa aagctggaga
    30601 cttgattgct gtctcaggta tggaagatat ctttgtcggt gaaacagtta ctcctgtgga
    30661 tcatcaagat gcgttaccta tccttcacat tgacgaacca acattgcaaa tgactttctt
    30721 agttaataat tcaccatttg ccggtcgaga aggtaaattc gtaaccgctc gtaagattga
    30781 agaacgtttg atggcagaac ttcaaacaga tgtatcctta cgagttgaac caacaaactc
    30841 tccagatgca tggacagttt ctggtcgtgg agaattgcat ttgtctatct tgattgaaaa
    30901 catgcgccgt gagggatacg aattgcaagt atctcgtcca gaagttattg aaaaagaaat
    30961 cgacggtgta aaatgcgaac cgtttgaacg cgtgcaaatc gatacaccag aagaatatat
    31021 gggtagtgtt atcgagtcct tgagcttacg taaaggtgaa atgcaagata tggtccatac
    31081 aggaaacgga caaatccgtt tgacattctt aacacctgcc cgcggtttga ttggttattc
    31141 aactgaattc ctttcaatga cacgtggtta cggaatcatg aaccatactt ttgaccaata
    31201 tctgccaatg cttcctggtc aaattggcgg acgtcaccaa ggggcgcttg tttcgatcga
    31261 tacaggaaaa gcaacgactt attctatcat gagtatcgaa gaacgcggta cagtcttcgt
    31321 agaaccaggt acagaagtat atgaaggaat gattatcggg gaaaacagcc gtgataatga
    31381 tttgactgtc aacatcacga aagcaaaaca aatgacaaac gtacggtctg ctactaaaga
    31441 ccaaacatct gtcatcaaaa aaccaaaaca attgacgttg gaagaatctt tggaattctt
    31501 gaatgatgat gaatattgcg aagtaacacc agaaagcatt cgcttgagaa aacaaatttt
    31561 agagaaaaat gctcgtgaaa aagcatctaa aaagaaaaaa taatctgtaa aaggatgaag
    31621 agagaaacca gcttgttata aaaaatagct ggtttctttt tttgtccaac tcttttctgt
    31681 ggagaagtca tctttgtcaa tggacataaa ttcagaaaat acgccgaaag acgtttaaaa
    31741 gacttttaaa aaacttattt ctagagagtt tttgtttcat aataagataa tgtttcacga
    31801 aaggagatca acttgtcctt cgaagaaaat cgaagtaaaa tggcaagaga aaggagcggg
    31861 aagatgaacg acttattaaa acaatacttt ggctatgatg agtttagacc tggtcaaaaa
    31921 gaaattatcc agaaagtcat tgatcaggaa aatgtattag gaatcatgcc taccggaagt
    31981 gggaaatcaa tctgttacca gcttccagct ttactattag atgggcttac tgtggttgtg
    32041 tcccctttaa tctctttgat gaaggatcag gtggacgcgg cgaatcaatt aggtataccc
    32101 gccactttta tcaatagctc gttagatggt tacgaaacag ctagacgctt ccaagaaatc
    32161 gatagacagc agtaccgttt actttatatc gctcctgaac gttttatcat gccggatttt
    32221 atccaagcaa tgaagcgatg gaacgtccgt atgatcgcta ttgacgaggc acattgtatc
    32281 tctcagtggg ggcatgattt ccgcccaagt tatttacaga tggcgaacca gctagatcaa
    32341 ctgccaaatc gtcctgtaat tgttgctttg acagctacag cgactgtgca agtagctgct
    32401 gacataaaaa gacttttaaa aattccagaa aacaaccata ttcagactgg ttttgaacga
    32461 gaaaatctac gatttcaagt aattaaagat caaaaaaaag aacaatatct aatcgaatat
    32521 ttaaagatca acaaaaatca atctggtatc atttatgcag caacgagaaa agaagtagac
    32581 cgtctctatc atttgcttaa aaaattcgat ttttccgtgg gtagatatca tggtggtcta
    32641 aatgagaatg agcgaacaga aatgcaagaa gcctttttat acgatcgctt gcagctgatt
    32701 gtagcgacaa atgcatttgg tatgggtata aataaaagca atgtccgttt tgttatccat
    32761 tatcaaattc ctggctctct agaagcatac tatcaggaag ctggtcgggc gggaagagat
    32821 ggtctttcca gtgaagccat cctgcttttc tctcctcaag atatccaagt ccaaaagttt
    32881 tttatccagc agtcccaaag agaagaaggg caaaagcaaa aagaatatga aaaattaaaa
    32941 gcgatgacag aatacgtgta tattgagtcc tgtcttcagc aatacatcct aaactatttt
    33001 ggcgagacaa gcagtccgtg caaccgttgt ggtaactgtt tagatgacag agaaatagta
    33061 gaagtaacga cagaagcaca gatggttctt tcttgcttaa aacgtatggg tgagaactat
    33121 ggtaaacaaa tgctgatgaa agtcttagca ggatcgaaag aacaaaagct gcaagcttta
    33181 ggttttggac atttatctac ctatggactg atgaaaaacc aatcgcaaaa agaaacgatg
    33241 cagttaattg aatatttgat atcgaatggc tatcttctga ccatcaatgg tgagtatcct
    33301 gttttgaaag taacagaaag agggatacaa gtattgaaag gacaagaatc tgtttatcga
    33361 aaggaaccca agaaagtcca gcagctatcg gatgaagaaa ccgatacact atttgaagtg
    33421 ctgcgggaac tgcgaacgga tctagcatca gaagcaggcg ttcccccgta tgtcgtattt
    33481 tcagattcca cattgaaaga aatgagccga atacgtccat caagcagatt ggagatgctt
    33541 cagataaaag gagttggcca aagcaagctt gataaatatg gcgaagcctt tttatctcgg
    33601 ataaaaaatg cggactctaa cgttctggat aagtagaaag aacgaatacg taaaaatgaa
    33661 taaaaacaac tggttaaatc tgtttttttt gctccttatg aaaatcaaat atgttataat
    33721 taaggaatta gaatgggagg taagcacaga tggattcttt gtcgaaaaaa cttgcgatcc
    33781 aagtattaaa tgatgaagca gaacggatca aacgattaat ccgaaatcaa aacaacagtc
    33841 tctgtatctc acaatgcaaa gccttcgaag aagtggtaga tacacagatg tacggctttt
    33901 cccggcaagt cggttttgct gtccgtatag gagtaatcgg aaagaacgag ggccagctga
    33961 tgttaagtga gctagaacga gaattgaatc agttatatag tgaggtttac caagaaattt
    34021 atgataaaaa agaagttggc aaggaggaat agacttgcct aagaaagtga aaaaaaggca
    34081 tctattagac tatagcatct tgattcccta tttaatttta tgtgtattgg gattgatcat
    34141 ggtatatagt tctacgtcgt atctattatt agaaaacgga caaaatccgt ccgcatcagt
    34201 cattaaccag agtatttttt gggtgcttag cttgattgct atcgcactac tttataaaat
    34261 gaaaacagat gttttgaaaa accagcgttt gatcatggca gccatcgcag ttttgacgat
    34321 tttgctgctg attgttgtgt tttttggtaa ggagatcaat ggggcgaaag gttggctgca
    34381 aattgcagga ttctcgatcc aacctgccga atacctaaaa atcatttcta tctggtacct
    34441 gtctctgact ttatctaaaa gacaaaacag tgtacaaaaa gattttcttg ggactgtgaa
    34501 acgtccactt gcaatggtta tcggacttac tgcattagtc gctattcttc ccgattttgg
    34561 taatgcggca gttatctttt tgattatttt ggttctgctt ttagccagcg gagtcaatta
    34621 tgtgtatact ttgattgtag gagtaggagg cttttgtcta agtactttta cgatctggct
    34681 gatcaatatc acaaacggaa agatcttacc cggacgttta cagtatatct ataatcgatt
    34741 tgctatttac caaaatcctt tctcagacga attaaataaa gggcatcaac tagtcaacgg
    34801 ctactatgcc atgttcaacg gaggactatt tggcagggga ttaggtaaca gtatccagaa
    34861 aaaaggattt ttacaagaag cacaaaccga ttttatttat gcaatcgtag tggaagaact
    34921 gggagtgatt atggggattt tgatattagc gttgctattc tttatgattg tgcgcattgt
    34981 ccttgtaggt atccgttcaa aagatccgtt caattcgctt ttgtgcattg ggatcggcgc
    35041 aatgtttttg atccaagtat ttgtcaatct tggaggaatt actggcgtta ttcctttgac
    35101 agggatcacg ttcccatttt taagtcaagg aggctccagt ttgctgatgc tttcgatttg
    35161 tgtcggcttt gtcctcaaca tcagtgcgga tgaaaaacgc aagagcttag gtttataata
    35221 aaaaaagatg taggagtggt tcgatgaaaa aagttttagt tgctaacagg ggtgaaatcg
    35281 ctgtacgtgt atttcgtgct tgtacagaat taggaattaa aactgttgga atctatgcag
    35341 aagaagatga atattccgta caccgtttca aagcggatga agcatattta gtaggacaag
    35401 gaaaaaaacc gattgatgcg tatctagata ttgaagggat catttctatc gcgaaagaat
    35461 gcggagctga cgctattcat ccgggttacg gtcttttgtc ggaaaacttg aattttgcgc
    35521 aacggtgcga agaagaaggc atcatttttg ttggacccaa actgcatcat ttagatattt
    35581 ttggagataa aatcaaagca aaagctgcag ctatcgaagc ggggattgct tcgattccag
    35641 gcacagatgg accaatcgct tctatagacg atgccttgga gtttgcgaaa caatacggtt
    35701 atccgattat gatcaaggca gctctaggcg gcggcggacg cggcatgcgt gtagctcacg
    35761 atgaaaagag tgcaagagag ggctacgaac gtgcgaaaag cgaagcaaaa gcagcctttg
    35821 gtagtgatga agtgtatgtt gaaaaataca tcgctaatcc taagcatatc gaagtacaga
    35881 ttctcgggga tacgcatgga aacgtcatcc atctttttga aagagattgt tctgttcagc
    35941 gccgtcacca aaaagtagta gaagtagcgc cttgtgtctc tatgaatgaa cagcaacgtc
    36001 aaaaaatctg ccaggcagct gtccaattga tgaaatatgt cgggtatgtc aacgcaggta
    36061 cagtagaatt tcttgttgaa ggagatgatt tttactttat cgaagtcaac cctcgcgtcc
    36121 aagtggaaca tacgatcaca gaaatgatta cagatattga tatcgtaaca acgcaactgt
    36181 tgattgctca aggtttggat ctgcataaag aaatcggatt gcctcagcaa gaaggaatta
    36241 aattaaatgg ttcagccatt caatgccgaa tcactacaga agacccgttg aataactttt
    36301 taccagacac agggaaaatc gatacgtatc gttcacctgg tggttttggc gtacgtctgg
    36361 atgtcggaaa tgcttacgcg ggctatgtag tgacaccgta ttttgattca ttgctagtaa
    36421 aagtatgtac gcatggtgct acctttgaaa cagccattca gaaaatggaa cgttgcttga
    36481 aagaatttag aatccgtgga gtgaaaacaa acattccatt tatgctcaat gtcatcacac
    36541 atcctgaatt ccaatcagga aatgcaaaaa caaccttcat tgatagtaca gcaacattat
    36601 ttgaatttcc tcgactacga gaccgcggaa acaaaacgat gaaatatatc ggtgaaatta
    36661 ctgtgaatgg ttttccaggt atcgaaagtg gcgaaaaacc attttatgaa gaaccacgta
    36721 tgcctaaaga tctaatcaca agaactgatt acgtaacggc taagaatgta ttagatgcga
    36781 agggtgccga tgctttggtc gaatggatca aaggacagga aaatttgttg ttgacggata
    36841 cgacatttag agacgcccat caaagtctgc tagcaactcg tgttcggaca aaggatttca
    36901 agcagattgc acgtttgact ggagaaggtc ttcctgaact cttttcaagt gagatgtggg
    36961 ggggagcaac atttgatgtg gcttaccgct ttttgaatga agatccttgg caacggttga
    37021 gaaaaattcg ttctttaatg cctaatacgt tgctgcaaat gcttttcaga ggttcaaatg
    37081 ccgttgggta ttctaattat cctgacaatg tattggtgga atttgtcaaa gaagcagcag
    37141 cgcaaggaat cgatgtattt cgaatctttg atagtttgaa ctggactcca caaatggaaa
    37201 aaagtatcca agctgtacgg gatactggta aaatcgcaga ggcagctatt tgctatactg
    37261 gcgatatcaa cgatccaagt cgggcaaaat acaatgttca gtattataaa gacatggcaa
    37321 aggaactaga acaactgggt gcgcatatca ttgcaatcaa agatatggct gggctgctta
    37381 aaccgcaggc agcttatcgt ttgattagtg aattgaaaga aacgacagat ctgccaatcc
    37441 atctgcatac tcatgatacc agcgggaatg gaatcatcac ttattctgct gcttcaaaag
    37501 caggagtaga catcgttgac gtggcaatga gtgcaatgag tgggaatact agtcagccta
    37561 gcatgagcag cttgtattat gcactggtca atggtccacg gctgccagaa atcacgattg
    37621 aaaatgcaca gaaattaaac cattattggg aagatgtgcg catgtattac aaaccgtttg
    37681 aaaacggctt gaatgctcct gaaacagaag tatatatgca tgaaatgcca ggaggacagt
    37741 attcgaatct acagcaacag gcaaaagctg tcggattagg tcatcgctgg gatgaaatca
    37801 aacaaatgta tcatactgtc aacttgatgt ttggcgatat cgttaaagta actccatcat
    37861 ctaaagtagt tggagatatg gcactattta tggtccaaaa tgatcttaca gaagaagata
    37921 tttatgaaaa aggcgaaaca ctaagtttcc ctgaatctgt tgtgactttc ttccaaggag
    37981 aactagggca acccgttggc ggatttccta aaaaattgca aaagattatt cttaaaggca
    38041 gacctgcatt gaatgaacgt ccaggtcttt tggctgaatc agtcgacttc aacgaagtaa
    38101 aaaaagaatt ggcagaaaaa attggctatg aaccaaaaca agacgaagta ttaagctatt
    38161 tgatgtatcc gcaagtcttt ttggactatc aaaaagcata taatcaattt ggcgatgtta
    38221 cattactgga cacaccaaca tttttccaag gtatacgttt gggtgaaaca atcaatgtac
    38281 aaatcgaacg cggaaaaacg cttatcattc gtttagatga aatcggagaa cccgatatcg
    38341 aagggaatcg cgtactgttc ttcaatttga atggacaaag acgtgaaatc actatcaaag
    38401 ataattcgat catcagtacg gtccaaaccc gattgaaagc tgaaccgaca aaccgagaac
    38461 aaattggagc aacgatgtct ggttctgttt tggatgtatt agtgaaaaaa ggcgataacg
    38521 ttaaaaaagg tgatacgttg atgattactg aagcgatgaa aatggaaacg gccatcgaag
    38581 cacgttttga cggagaagtc gcacatgtat atgtgtcttc aggagacact atttcgtctg
    38641 gtgacctttt gattgaagtg actgagaaat aataagcgaa aggtggggaa acatgaaaag
    38701 actgggtttg ttttggctga ttctgctatt agttattgtg gcattctaca tggaaccagt
    38761 cttgtttccg ccaaaacttg aagtgaagga aaactctgat caacaaatat caaaccaaat
    38821 gacaacgtgg aaataccagg agcttaaagc aactggtttt tctacttata tcggaaaacc
    38881 gatcgatcag ctggaaaagg attttggcca agcctatgat cgattaacta gcggatttgg
    38941 ttttgaaaca agatattatg aaaataaagc tagtcatctc acatttgaag cgaacatcca
    39001 agacagcaga gtcacaactg ttaaagtact gcaaacaggg cctgctgata tcgcgccgtt
    39061 ttatttaggg atgacgatgc aagatcttac gaaaatcact actatctata ctaatttcac
    39121 ttttgagtac catgatacag aagttggaat cgaactaatg gaagaggata tgaattatcg
    39181 tccgctaatt gcttttgata acgacacttt tgctatttta ttttttgatc aaacaacaaa
    39241 cggcctattt tcagttgtgt atttagataa agatagtctt ttgaaactat tgccatatca
    39301 agtgtttggt gaaggccttc cacattatca agcagataaa tcggctgatt gggaatcaat
    39361 caatcgcgtt aaagaacgaa aaagtacgac tttattaaat atgcttagaa gagaagacga
    39421 acttcccata tacaatcaaa cacttgcctt tcaaaaccac agtcagctgc tactacatga
    39481 ttttttgaca aggcctgagg aaatattgtc agaggaacgt atggctgatt ggcaaaaatc
    39541 gctaggcagt gctcaaacga cagtgaaatt ctcactgacg aatgatgaat tggagaagtt
    39601 aatcagtaaa caaaaattag aaaatactag tgggctattt attcatccgg cgattgacgc
    39661 tactttttcg tttttatatt ggtacagcga tccttacaac catgaccgtt tcatggaccc
    39721 gggaacggat tctgtaggca ttgctttttc taaagaaaat atgttagtct tattgcaaga
    39781 agaaaacgga gaaagtagtg atagcagtga tcgttaacga agagctgttt caactggagg
    39841 atcaatgcct ccaagtcgct gaaatgataa aaaagagtaa aacgatggct tcttatcttg
    39901 aacataaaca gtcaatggaa gaatctgcaa aagtttgcca gttgaaagaa gcgttcttgt
    39961 ctaagaaaga agcatttgaa aatgtagcgg catatggtga gtatgcacct gattatcgtg
    40021 aaaaaaaacg agctgttcga aaagcaaaaa gacagcttga tatggatgag catgttgcag
    40081 ctttccgata tagtgaaaca cagctgcaaa gtctgttgga tcaaattgtc caagtacttg
    40141 ccgaagaagt ttctaatgaa atcaaagtag atgcaggtag cccgtttttt gaaacgaaaa
    40201 aacactttgg atgcggaggt aattgtcatg caattagaca atagtgaatt tgaaataaca
    40261 aaacgacgcg ggctgatcgt atgggtctac agcttaaaac aattaaagaa tctgaaaaag
    40321 ttcggcttgt tgcattatgt ctcaagaaga atgaaatatg tcgtgcttta cttaaatgaa
    40381 gagacattgg aagaaacaga agaacgaatc cgtaaattac attttgttcg aaacgtagaa
    40441 cgttcttacc gaccggatat cgaaatgaat tttgccgaaa aaataggaaa caaaacagta
    40501 ttaaaagacg aaggtttcga aattgaagag ctaaatacag aaatccgatt agctgaacat
    40561 ctttaaaaat ctcttatgag cagtttttaa ataaaaaata acttggataa cgatcgattt
    40621 ttgatcattg tccaagtatt tttttggtat actagtacca gtaccatttc taaggagtga
    40681 gtagatgcgg ataatatcag gaaattatgg cgggcgccgt ttaaaaagtt tagcaggggc
    40741 gaacaccaga ccaactacag ataaagtaaa agaatccata ttcaatatga ttggaccata
    40801 ttttgatgga gagacagtat tggatctgtt tgcaggaagc ggtggtttag ctatcgaagc
    40861 agtatctaga ggctgcagtc atgcggtatg cgtagacaaa aattaccaag cgctaaaaat
    40921 catcaaagaa aacatcgaaa ttacgaaaga accagagaaa tttaccacaa taaaacttga
    40981 tgcggacaaa gcaatcgaac ggctagcagc ggagaaacaa caattcgact acttgtttct
    41041 tgatccgcca tatgcaaaac aaaaaataat cgatcaaatc cataaaatgg aagaactggg
    41101 acttttttct aaaaccgcag ttatcgtatg cgaaacggat aaaacagtcg aattgccaga
    41161 aactgtggct ggattccatc aaataagaaa acagatttat ggcataacgg ccgtaactat
    41221 ctatagaaaa gagggaaatc aatgaaacgt gcattattcc caggaagttt tgatcctttt
    41281 acaaaaggtc acttagatac ggtggaacgt gcggctaaat tattcgatga ggtagtaatt
    41341 ggtgttttta tcaatacttc aaagaaaagt ttgtttcccc cagaagaaag aatgacattg
    41401 atcacaaaag ctgtttctca tcttcctaat gtaaaagtca tgcatcaaga aaatcaattg
    41461 acggtagaaa cagcaaaaga gattggtgca gatgcgttga tcagaggcat acgaagtatc
    41521 aaagactttg aatatgaacg agagattgct cagatgaatc atcatctata tgatgaattg
    41581 gaaactgtct tcttattagc aaaaccagaa tatagtcacg tgagttccag tattttaaaa
    41641 gaagtactgc actttggcgg agatgtgagc agctacttac cgccagtgat caacgaagct
    41701 ttagctggaa agcgtgaatc aaatgaaagc taaacaatgg ttgaaaacag tactgattat
    41761 catatttgga atgttgatca ttggatttgt agtagttccc ttgccgtatt atgtagaatc
    41821 accgggagcc acgatcgatc tgaaagaact aattacggtc aatgataagg aagataaagg
    41881 ttctgggtct ttctctctta cctctgttgg tatcaggcaa gctacaggtt tcttagcttt
    41941 aaaagctaaa atgacccctt ttgaagaatt gatcagtgaa gaagaattga ctggtggggc
    42001 gacaaatgaa gaatataatc aaatgcaaca gtattatatg gattcttccc aaaatgcagc
    42061 aatcgaacaa gcgttaaaac ttgcagacaa gccttataaa atggaattca aaggcgtata
    42121 tgtcatgagt gtagagaaaa catcgaattt ctttggcaag ctttcagttg gagatacagt
    42181 aacaaaagta gacgggaaaa gctttcaaag tacagaagca tttatggatt atgtaaaaag
    42241 ccaaaaagtt ggacaaacaa tcgaaatcag ttatttgcat aatggtgaag aaaaaacagc
    42301 ttctggtgat ctgatcgagt taccaacaga taaaaaggca ggaataggta tcacgcttac
    42361 tgaccatacc gagatcgaat cagatacaga tgttcgtatt aattctggct ctatcggtgg
    42421 gccatcagcg ggattgatgt tcactttaga aatctatgaa caagtcactg gtaaaaactt
    42481 gcgacatggt aagcaaattg caggaactgg aacgatcaac agtgaaggag aagttggccg
    42541 aatcggagga atcgataaaa aagtggcaag tgcggataaa gctggcgtag agattttctt
    42601 tgcaccagat gatacgattt cagacgatgt taagaaagaa tatcctgaaa taaaaaccaa
    42661 ctacgaagaa gcaaaagctg ccgctaaaaa attgaattcc tcaatgaaaa tcgtaccagt
    42721 aaaaacagta caagaagcgc ttgactatct agagaaaatg aaatgaaact aaataattaa
    42781 agaggggttg tgacacgagt tctgtcacaa cccctctttt tcgtcaaaaa tcttcacgat
    42841 aaaaataaaa acaaaagaaa aaattgacgt aattagatgt tgaagggacg attttgccag
    42901 agctcactgt ttcttcaatt ttaaatgaaa ggagtaatga atgattttta ctggtcattc
    42961 tttgaaaaaa gaacaatgat agaaaaaatc agcaagaaaa tactagcttc acccaaattg
    43021 atcatttgga tgtctatgat agttcttatc ttttgtatcg caagtggttt tttattatca
    43081 aatttgctat tttatagaga aacagaagag actgctgcaa aagaaatact ttcttcgttt
    43141 agttccagtg gagaagatcc atcagctgaa ggaaacgatg tagaagagga tgctcgtcca
    43201 aaggtcatgt acaccgatat caaaggaagt gtgaaggagc ctggtatcta ttccttttct
    43261 tcagaagaac gggtctatga tgtactaaag cgtgcaggtg gattattaga agaagcggat
    43321 agcgatcgaa tcaacttttc tgcgaagata gaagatcagc aagtcctata tatccctgct
    43381 gtaggtgaag agctgccaga acatcttgat cagttggcat cctcggaagg aaaacagcct
    43441 acagcagatt ccgagcctcc caaaataaat atcaatacag ccactccatc agaacttcag
    43501 cagattcctg ggatcggatc agtcaaagcg caagaaatca ttcgatttag agaagaaaac
    43561 ggatccttcc agaaagtgga agacctgcag gagatttctg gtatcggtga aaagacagtt
    43621 gaaaaactaa aaaacttcgt tacaattaaa tagaatgatt caaaatcgac tggcacgagc
    43681 aataaatgga cgctaatgga tactaagaat aatccaattc taagagcttg gcaggacgag
    43741 gaggtagtat ttttggatag gaaatagctt gattgttcgc aaagaaacat taaaaaaacc
    43801 aatgctgaat gtctatctcc aaaataaaat atctgggatt catattatga atacggctgt
    43861 cagcggcaat aacagtcaag ctctacgaga acgctttgcc aaagatgtac ttagctatac
    43921 agcagataaa gtatttattc tcattgggac gaatgatcta gcagagcata aacaactttc
    43981 taaagaaacg taccaaaaaa tctgcagtgg atgatagttc agctgaaaaa agactatagt
    44041 tctgatcatg ctttctttat cacgccacca gcagtcgatg agacaaaaca aaaatatcgg
    44101 aataacaagt tgatcaaaga atatatctct gttctcacag aagtagcaaa acgccatgat
    44161 tgtgaagtat cgatttttat acggaatttc ttgaacaaat ggattcgaag aatttttata
    44221 atgggctaat ggatgacgga cttcatttcg gcagtgaagg gtaggatctt ttgtcagaca
    44281 ggatgattcg ttatatttaa agaatatttt gtttaagcaa tgagtacttt ttaatcaact
    44341 tgaaaaaacg gaggaatata aaacatgtta gaaaaatctt caaaagcatg cgatacgaat
    44401 aaagaaaaag ttactgataa gtcacataat gaacgcattc cttgggacca gtactttatg
    44461 gctcaggcag tactgttatc tttacgtagt acgtgtacac gtttagaagt aggagcgaca
    44521 ctcgttcgag aaaaaaggat cattgctggc ggctataatg gagcagtcag tggagatgtc
    44581 cactgcatag atgaagggtg ttacgtcgtg gatggacact gcttgcgaac gatccatgca
    44641 gagatgaatg cactcctaca gtgtgcaaaa cttggtatcc cgacggaagg ttcagaaatc
    44701 tatgtcacac attttccatg tttggcctgt acaaaggctt tgttgcaagc tggtgtgaaa
    44761 gggatcaatt atctccatga ctatcgaaat gatccttatg cccaagcgtt gatcgaacaa
    44821 ttaggtgtat ctgtacacca agttgcttta gactcacagc atttttcaaa acttcaaaat
    44881 gaattaacag gaaaacatgt ctagcgtttt agaaaggcat gttcgaaatc ggttgatttt
    44941 tccggcaatt acgtcgatga ttatctgttt gttgtattac actgacaatt ggggttatcg
    45001 tttgcttctt gccggaattt ttttatggtt ttcgctaaaa gaaggacgtt ttatcgcgta
    45061 cttgtgtatt ttgtgtagca taacggtatc catttcttat aggctacaag agtattcatt
    45121 tttagaggaa aaaacaacat ctgcgcaaat tactgtattt acagatacga ttcgtgcaaa
    45181 tggtaatttt ttgacaatgg aaggaaggtt atcagagaat aaacaaaagc tccagctttc
    45241 ttatcaagta aacacagaag cagaattgaa aacatggctt aacttccgag gaaagggaat
    45301 agaattgact gctgaaggcg agttcatctc tccagcaaaa aagcggaatc tttataattt
    45361 tgaccaagaa gcttacttca ggaaccatag aatttctgga cggttccaaa ttcaaaagat
    45421 tgaacagatc accatgcaaa atcactggcg aaactggctt cagagaaaaa gaggatcttt
    45481 tatctccttt gtccaatctg aatttccgca aaaaacaagt gtatatatta attctttatt
    45541 atggggctat aaagatgcag gattcagaga accagaagaa atttttaggg agagtggttt
    45601 gctgcatctg ttcagtctat cgggtctaca catccaattt tatttagggt ggctgtatta
    45661 tttgtttcga cgtatcggat ggccactaca cgtcagtatt attccgttga gtctactaac
    45721 tatctgttat gtttctattg caggaagttc tatttctgtt ttgcgtgcta gtttgctgtt
    45781 tttattgcga ttgctagtca aattgctgaa taagcattat tccaccatgg acttatttgc
    45841 agttgtcttt tggcttcttt tactatttga tcctcgattt ctttttcatg cgggtggaca
    45901 gcttagtttt ttcatgagtt ttttgtttat cctgatttct tttgatggag attggttgaa
    45961 aaaaacggcc tctcacgtcc tgtttactat gatcacgatg ccgttgattg tatggcattt
    46021 ttatgagtgg cctattttag gtagtctttt tacattactg attgcaccgg tattcaagtt
    46081 tctttttctt cctggtgtgt tatttctcac actcttcaat cgctggctgc cggaaacttt
    46141 acttttgctg atagaagagg gattaatctt atttgagcga ataatcgatt tttcttcagg
    46201 gtcgtctctc attataggac gtttgcccct tgtgctatct gggatgtata ttttcggatt
    46261 actgatttgt atggataggt tgaaagaaca acctgtgaaa cacttgtttt atgttggtct
    46321 tttttctttt atttttttga ctttgccatt tttacgcttt tcttcaacga tcgcttttat
    46381 cgatgtcggt caaggagaca gtatcttttt gcaaagtcct tttcgaaaag aaacgatttt
    46441 gatcgatact ggaggtcagt tacactttga aagagaaaag tgggcgcaag gtatgatacg
    46501 tcctcctgct gaaagaaata tcgttccata tctaaaaggt caggggataa gtgtaatcga
    46561 taaactcatc ttgacacacg acgatacgga tcatgtggga gaattaccca cgttatctca
    46621 gcattttact atcaaaaaaa tttatatcgg ttggggcgct ggacgaaatg agccattaca
    46681 aaggcattta tctgaagctc aaaaaaatgg tactgagatc attgaaatca aacatgggga
    46741 caggatcagc ggttattatg atctttatgt attgactcct tttgaaaagg gagagggaag
    46801 aaatgaagat tcgattggtc tatggatgga atataacaat aggcgctttt tatttttagg
    46861 agatttgaat caagcaatgg aaaaacaatt gcttttgatt tatcctaatc tgaaagccga
    46921 tgtagtcaaa ttaggtcatc acggtagccg tacgtcaagt aacacagatt ttctttccca
    46981 tattgaagca aaacatggga ttatatcctg cggcgtaaat aatcgttatg gtcacccgca
    47041 cagcgaagta ttggagacac tagaagaaaa tcagataaaa acatggcgaa cggatcaaca
    47101 aggaatgatc acctatcgct ggcatccagt ttttcatcct catgggctag tggaaacaat
    47161 gatagactag taattctcat ctgctcatgg taggataatt tttgaaagtg gtgagtaatt
    47221 tgagtataca agcagagtta caaaaaatac gtaaagaaaa acttgcatct tgttacttga
    47281 ttttaggaac agaaaagttt ctccaagatc aagttcggac agaaattgtc aaaaaaatcc
    47341 aattagaggg cgaagatgac ttaaattttt taagttttga catggaaaat gcaagtttag
    47401 atgaggtagt agctgaagca gagacgttgc cgtttttcgg agatcaacgg ttagtattcg
    47461 tagagaatcc ttatttttta acaggtgaaa aagtaaacaa tggaatcgaa caaaatactg
    47521 atttattgac ggcttatttg aaagaaccat tagaatcgac tgtattagta ttctttgcgc
    47581 catatgaaaa gttggatgaa cggaaaaaag taacgaaaca attgaaaaaa acagcaatta
    47641 tcatcaatgt ccaacagttg aatgaaaaag aagtacgtca atatctgatg aataccttag
    47701 agaattcctc aatcaaaatg gaacgaagtg caattgattt attcttgagg ttgaccgact
    47761 tagatttatc caaaatgatg agagagttac agaaattggt cctttatgga caaaatcaac
    47821 agcaaatcac ggtaagagaa gtagaagaat tagttcctaa aacgttagaa cataatattt
    47881 ttgacatgac ccaatatatt ttaaaaggga agacggaaca agctttgcgt ttatacgaag
    47941 atttagttat gcaaggggaa gaaacaatca aaattaatgc gattttgctt tctcaattac
    48001 gtttattttt acagacaaaa tttcttgtaa agattggtta tcagcaggca aatattgctg
    48061 aaacattgaa aatccatcca tatcgtgtaa aacttgccat gcaggaagta aaaaaattcg
    48121 atgaacattt gctggtacag ttgtttgatc aattagttga gatggattat caaatcaaaa
    48181 cgggacaaat cgaaaaagaa ttaagttttc aactattcgt tttgcgcaca gggcagttgt
    48241 taagaaatcg ataagaagaa agacgagggc aaagcatgcg ggaaggtcgt ttgtttttgt
    48301 cctttttttg acaaataaaa aaatcggccg aagccgattc ttttatttag cgattttttt
    48361 gcttaaacga gatttgtcgc ggttagcttt gtttttgtgg attagacctt ttgattcagc
    48421 catatcaata gctttaacag cttctttata taacgcatct acgttgtcag cacctgaagc
    48481 tacagcatct tcaaattttt tgattgcagt acgcatagcg cttgtttgag atgaattttt
    48541 cacattagcg ttttcgcttg tacgaacacg tttgattgca gattcaatgt ttggcattag
    48601 tttcacctcc gataacttaa gttcttacgc gtgttaccgc ataattcaac attcattatt
    48661 atacctaaag gcagcgtgct ttgcaatatg aacatgacaa gtttttttcc ttaacagtct
    48721 tttattagga ttttttttca gtaaaaacgg atagtacaag ctgaaaaaaa tcaaaaagac
    48781 gctattgtgg gaggcaatag cgtcaaacca aactagattt ttatttatct atttaaacaa
    48841 agtttgaatg ggaatgtttg gtactaagtt attatataac aaagagaacc gtttgcaaag
    48901 ttttttttga aaagggatac gattccctgt tgttctttgt ttttctatta agaaactgca
    48961 gttattttat aaccagtatc ctttgatcag taaaggctat tctggtgtac cgattatttt
    49021 aatgtattca tcgatatttt ttatcaacat tttttttatg accaactggt tccgacggtt
    49081 ccatttgcca cttacttcca gcacatattt atttaggggc aaacgtaaga tatattttgc
    49141 caaatagcga tctttaagca ggccattgat cacacggtcc tcaagctgca agttgatccc
    49201 agtcagcatc attggctgtt cttgtaaaac gtacgtatca attaaaagac cttcaaaagt
    49261 ttccacaagc gtcttccttt cttttcaaag taacctgaaa acaggcacta attcttccat
    49321 tttgatattc gttgaagtgg atgcgatcat tctttctttt gtccactgta atctagtata
    49381 acaaaaaaga gcagaagagc caaaaagaaa aaagagcatc gaattctata ggaagtctca
    49441 ttggcacggc ctaaattatt acaaaacatt gattaaaaaa agcccctgca tcgcaggagc
    49501 atcccctata tcgttttaat aggtcaatca aaaagcagta tcaaacacat tttgtatcaa
    49561 atcaggaaat aatagataag ctaagcccag aatcaaaagt accgctagaa gaaaccagcc
    49621 gattgttcct atgaaatact ttaatttttc gaacattgta tcacctcgtt gtcagtatat
    49681 cacggatcag taaattgggg gtgttaagaa tctcctaaaa tagacaaaat ttgttctatt
    49741 ttcctaaagc aaatacttgt aagatacagt aagtgatacc agaagcaatg accggtccgg
    49801 cggcgattcc tcttaagaag acaacaccta aaatcgtgcc gaaaacaagt gcaacagtga
    49861 tttgtggatc agaagcaatc aatcctacac ccttggaaga taagacagcc actagcccac
    49921 cgcaaaaaac agctacccag ccaatagggg atttaaaggc ttctaataga tcacgtagac
    49981 cgatttctcc tgttgcgata gggattagaa tagccgctgt gatgatcgtc accccaatat
    50041 tgattccttt gccttgaagc caagggaaaa aggaacggga ggctggtatg agcttcataa
    50101 tcaaaacaaa agctgccgct atcatcagac tttgattttt agctaaaatt gctacaagta
    50161 aaataattcc taaaaaaagc caactttcca tgaaatatat tcctcacttt cttcgaaaca
    50221 atcataacat gtttttagaa agttacaaaa gtaggaattc atccttcaag acctattcat
    50281 aagctgtttt tttcataaaa taaacaaaat cataaaaaaa cactttgctt atttgacaga
    50341 agacagccgc gctttgtata gtggacaaga cttacatttt tttgaagaat cagaaagatc
    50401 aggtaaaggt cttagtaaac gcaagccatt cagaataacc aatattgtgc ttccttcgtg
    50461 tcctacaact ccaagaggta gatttaaaaa ttgcaggaag ttagaagcaa tcaacaagag
    50521 aataacaaga atcgaaaaaa taatattttg tttgatgatc cgccgcattt ttaaagatag
    50581 ccgatgactg tagacaaatt tatttaagtc gcttttcatt aagacgatgt ctgcgatatc
    50641 catagcggca tctgtccctt gccccatagc gacacctaaa gaagcggctg ctaaagcagg
    50701 cgcatcattg actccatcac caaccatcgc atttacttgg taaagttcat tctctttttt
    50761 gactagttgt gttttttctt ccggagtaca gcttgcatag taatgttcaa tccctacttg
    50821 ttcagcaatg gcctttgctg tgccagaatg gtcgccggtt atcatacttg tatggatgtt
    50881 ttgggattta aagtaggaaa ttacttgttg ggtatttgct tttggaatat ctagcagacc
    50941 taaaacagca attaactgct gatctttaga aagataaatc acggttttgc cttgattttc
    51001 caaacgttcg atcatttccg caatctcttt gctgattatc atcgtctcag gatcatatgc
    51061 gtgcttgcca actttccatt gcgcacctaa ataggtagtt tgtaatccaa aaccagtaat
    51121 ttcttctatt ggtaagtatt ggatttcttc aggtattgtg caatcgaaat attgcaaaat
    51181 cgcatgagca agtggatgcg tcgttttttg ttccatagca acaagaagtt gttgtgccaa
    51241 atccttttca tcaaagaaaa agctgtcagt tacaactggt tttcctttag tgagcgttcc
    51301 tgttttatca aaggcaatcg cttttaattc agaaagcttt tctaaatgga taccgccttt
    51361 gattaaaatc ccattttttg cagaatttga aagagcagct agagaagctg gtgtagcaga
    51421 tgcgacaagc gcacaaggag aagccacaac taataatacc attcctcgat aaaagctttc
    51481 atcccaactc caacctagga aaaagtgggg gagaaggatc attagaggaa cagcaagcaa
    51541 aatcaatttt acataattat tttcgattcg ttcgataaat gaagctgttt gagttggcgt
    51601 attctgcgct tcttctacta attggataat cttagcaaag acagtttcgg aactcgtttt
    51661 tgttactcga atcgtgatgg gatttccttg attcagcgtt cctgcataca tctcatcgcc
    51721 taaatatttt tctacaggca cagattcacc gcttaatgca gactcatcga tcgttgcctg
    51781 tgtgctttct aaaaagccat ctatcggaac agctgctcct ttagcgacaa ataccaagtt
    51841 atccaccttt agttgagaaa catctacttc ttgcatttgt ccattttctt ttaataattg
    51901 ggctttttgt ggttgaagat tcatcaaagc agtaatttct ttttgacttt tattagttgt
    51961 gtattcctct aatgcaccgc ttaaacaaaa gatgaatgtc aacattgctc cttcaaagta
    52021 attaccgatc aaacaggcac caatagcagc taaagccatc aataaatcca cattcagtgt
    52081 ccgatcattc cacaattctt tcaagccttc cgatgtttgt ttatatccac cgatgataat
    52141 ggcactgata taaaaaagtg gggtgatggt aagagagaat cggtcgaaga taaaaccgaa
    52201 gatcataaat aaaaggcagc cgattgttgc tgcaaaagct tttttctgat tagtcatcgt
    52261 tattagacct ccttgtcaaa acaaggatag cataataaaa atgtaattga taataataac
    52321 agctaaatga gaacgataat ggttatcatt tggtgattaa gcttgatgtt gtttttatta
    52381 tttataatga ttattattaa agaaaataaa aaaccagaac atttctcaaa taagagaagt
    52441 gttctggttt tttctacatt gcaataaacc aataaccaat caaaatgata ccaaggataa
    52501 tacgatacca gccaaaagcg gtaaagtcgt ttttcttcaa atagcttagt aagaatttga
    52561 tagctaagac ggaaaccaca aaagatacga atgttcctac aagaagaaca acagtttctt
    52621 ccattttgaa tgaattccct tcagctaaat atttgacgat cttcaagccg cttgcgccaa
    52681 acatgacagg aatccctaag aaaaatgaaa actctgtagc gacaaaacgc gaagcaccaa
    52741 tcaagataga tcctaggatc gttgcgccag aacgggatgt tccgggaaca agtgccaaga
    52801 cttggaataa cccaacaaga agagctgctt ggtacgtaaa gtcattcaga gaagtccaac
    52861 gaggtgtttt gtttttgttg cgtttttcga caataataaa ggcaataccg taaacgatca
    52921 aaacaatggc aactggtaag aacttgtgga aatttgcttc taaccaatca tccaaaggca
    52981 aaccaatgat gatggctggt atgcaagcaa cgatcacttt aaaccaaagt gtccacgtat
    53041 cttttttttc taccgttgat ttacttggag aaaatgggtt taacttgtga aaataaagaa
    53101 cgacgacagc caagatcgcc cctaattgga taacgacatt gaacatcgac ataaattgtg
    53161 aactggcatc cagtttgatg aattcatctg ctaggatcaa atgaccagta ctactgatgg
    53221 gcagccattc cgttattcct tcaataatac cgagaatcac tgctttgata atatttgcaa
    53281 aaaacataaa ttccttcctt cccaattaag atacatctta tagtataccg ttattttttg
    53341 agaaacccaa tctgtttttt aatattaaga aaaacttgag aaataaagca gataagtaca
    53401 cgaagagaaa aaagaagaca aagccctcgt tcagactttg ccttttatga ttctctggta
    53461 aaaattaaaa tatccccatt atagaaacga gtcgcgacta tgtgttttcc cgttatcgat
    53521 ataagacgta tcattgatgc cgtggataga aaatcgaccg tttgcataag tgacctttgt
    53581 tacgctgcca tttaaaagcc cagcacgaac aggctgttta ggatcgatca gattaagcaa
    53641 aaaggcgatc gtcaaaccat gagatacgac taaaacattt ccaccaccat ttttttcgca
    53701 gtgatgggcg atatcttcaa atcctgtcca tacacggtct cgcaatgttt cataagtttc
    53761 cgcccaccca gcggtatcta agttgtatac agcattagca atttgttcaa aagaaacttc
    53821 tgtggtaaac atttcatcat atgttttaaa attcaataca cgagggatca caccccacat
    53881 ttccatgtca tatccacctt caagagaccc gaaacaccat tctctaatcc ttttttcaat
    53941 aaaataagga atttcttttc ccttagaatg ttctcctaga ataatacggg cagtttcgat
    54001 tgcacgacca ctgtcactag aataagcaaa tgaaaagtcg acatttttta acccgcgacc
    54061 taaataatga atgccttctt gtccttgctt tgtgaggggt gtatcacacc agccttgtac
    54121 tcgttcaatt gtattgaaca tcgtttttcc gtgtcgtacg atataaagtg tagtttctgt
    54181 cattttattc tcctcctaag tcgttttaac gattgaaaaa aggatttgtc cttttttcct
    54241 gttcaatcgt cgttgcatcg ccatgtcctg gatagactgc aaattcatca ggtaatacaa
    54301 acagctgggt ccgaatacta tgaagtaatt gttctaaatt ccctgtatac agatcggttc
    54361 taccgatact tcctctaaac agggcgtcgc cagaaacgac aaaatcatca aaaataaagc
    54421 tgacgcttcc tatagaatgc cctggggtag ggacgacgcg aaaagacatg tttcctaaag
    54481 tataagtttt catttcaaat tcatattctg caggcgagac aataacatca gcaatatcat
    54541 catgtctacc gagtccagaa agattcaaaa tcggatcacc tagccatttt tgctctagtg
    54601 ggctgacata aactgggatt tgataatacg cgcgtaaagg ttccactgca ccgatatgat
    54661 cgtagtgagt atgggtaagc aaaatcgcta ccggctgttg gtttgttttt ttgatttctt
    54721 gtttgattcg ttccgcatct tctccagggt caatgatcaa aagtgcttct tcgttgtaga
    54781 ccaaataaca gttttcttca atcattcctg tttttaatct ttcgatatgc atgtgcattc
    54841 ctccttgata gccaaaactt ctttcatcca ttagtataac gcattcattg ctaggaaaca
    54901 aaaacaggta cttatttctc tttacttatc tgaattatca gactatatga aaagtatttg
    54961 gatattctaa agagaaggaa agtaagtttt catagcattt taatatgtcc ttgttacatt
    55021 agattcatcc aaaaatccaa attctatatc ctatatccct gcctaatcag cagggtgttt
    55081 ttttatgttt ggaaagagag ctctttttgc taaactaggt tttttcaggt aatcttagag
    55141 agaaagaggt ggtggaaatg atcaaacagt caaaaatatc tgtgcggcac ttagtagaat
    55201 ttattttgcg acgtggaagt atcgacaatc gtaaaaaaag taaccatact gcattagaag
    55261 gagcgagaat ccaccgcaag ctccaaaaag atgcgggaga aaactatgaa aaagaagtct
    55321 ttttaaaaac aacagttcaa ttagatgaat attacctgat cgttgaaggc cgtgcagacg
    55381 gtattttcaa aagagacggt atttattata tagatgaaat caaaacctcc gaaccacgat
    55441 ttgaagattt agaaccagaa caagtggaac ttttctttca tcaagcaagg gtgtatgcct
    55501 atatctatag tcaagaacat gatttacaag aaataaatct gcaattgact tacttccaga
    55561 cggcagaaga agtgatcacg agaaaggttg aacatcagac aagagagcag ttagaaactt
    55621 tttttaaaaa gctgactgaa gattataaag aatggcttgt ttttcaagaa aactggcgca
    55681 ctgtacgcaa tgcctctttg atggctttga aattccccca tgatgagtat aggaaaggtc
    55741 agcgtgaact agcggtagct gcttataaaa cgatccgtac gaaacagaaa ttgtttgtag
    55801 aagcacctac cggaacagga aaaacaatct ctacgttatt ccccgctttg aaagctgtag
    55861 gggaagaaga gggagaaaag atcttttatc taacggctaa aacaataact agacaagtag
    55921 ctgaagatgc tatgacagca ttaaaagata caggagctga agtaaaaagt gtcactttga
    55981 cggcgaaaga caagatctgc tttttagatg agacgacctg taatccagat cagtgcccat
    56041 atgccaatgg ttattacaat cggattaatg aaggtttatg ggatcttttg aatcatgaga
    56101 atcagatcac tcgtgaagtc atcgaaactt atgcaagaaa gcatacactt tgtcctttcg
    56161 aactatcatt agatgtcagt atctggtgtg acgtaatcat tggggattac aattatttat
    56221 ttgatccaac tgtttattta agacgttttt ttgaagatga aaaaaacgag gactatctgt
    56281 ttttgattga cgaagcacat aatttggtga atcgttcccg agagatgtat tcggcagaac
    56341 tatcttatga aaaaacgaaa cgaagtaagg aagctatacc aaaggaattc aaaaaacttc
    56401 atcgccgttt caacaaacta ttaaaagaat ttgattcgat ccgagaaata gcaaaagaag
    56461 atcattggga ttatcatcat caaaaagcac cggctgaatc tttagtaaag gcaggttatc
    56521 aattaagcga aaaaattaaa gaatggctgg cagaatttcc tgagcaccca tcacaagaac
    56581 aattgcttcc ttattatttt gatttgcttc attttttgaa ggtcagtgaa ttttatgatg
    56641 atcactacga aacaacagtc gaaaaaacgt atcgcgatct gatagtaaaa gagttttgta
    56701 ttgatccaag cttgtttctt gagcagtcgt tggataaagg aaaaagcagt attctttttt
    56761 ctgctagttt ttcaccactc tcttattatc aggaaacact ggggggacaa aaaagtctgg
    56821 cttacaaact gccgagtcct ttcccagaag gaaaccagca agttttcatc gcaaattacc
    56881 tagagacgac ttatcgaaaa agggaacaca gtctggcaaa attagtagag acgattcatg
    56941 cttttgctga tggaaaggtc gggaattatt tcgttttctt tccttcttat caatatttag
    57001 atcttgcggt ggaagcattc agacagcaat atcccgacag caatgtgcta atccaagaaa
    57061 cggacatgaa tgaggaagaa cgcgaacgat ttttaacaaa atttcaaaca aatcccgctg
    57121 aaacattgat tggattttgc gtacttggcg ggattttttc agaaggaatc gatttgagag
    57181 gggaccgatt gatcggcagt atgatcgtag gtgtaggttt gccgcagatg aatcatgagc
    57241 aggaactgat caaatcatat tatgatgaga aggaacacct tggatttgct tacgcttatc
    57301 agcttcctgg aatgaacaaa gtcttgcaag ctggtggtcg agtgattcgt ggcatggcgg
    57361 atcaaggaat cgttgtattg gcagatcaac gattttctag tttttcttat cgacgtttat
    57421 tcccacaaca ttggcaaaca gcaagagaag tacgaagtgt tggggaattg gaagaaggaa
    57481 tacagcgttt ttggttatca aaagaagcag taaatcaaaa aaacgaggaa tgacagacgt
    57541 cagcctcgtt ttttgattaa cgatagttag tgaattgcaa ctcgattggt aagtcaagtt
    57601 tacgtaataa agcaatcaca gcttgtagat catcacggtt cttacctgtc actctaatct
    57661 gatcttcttg gatttgtgct tttactttca gtttttcatt tttgatagct gtagtgattt
    57721 tcttcgcgtt ttcacgatcg attccgttga ccaaatcggc agtttgtcga gctttgccac
    57781 ctagagcgtg ttctgattcg gaaaaatgga tatttttgat tggcacattt cttttgatca
    57841 gcttaccaaa taatacatct ttgatctgtt cgattttgaa atcatcatcg ctcaatacaa
    57901 ctagattgct gttctctaat ttgatttcta ctgtagaatc cttgaagtca aagcgattgg
    57961 acaattcttt tgttgtttgc tgaatcgcat tttttacttc ttctgtattg acttctgata
    58021 caatgtcgaa gctagcatct tttgccatag gaaccctcct gatatacata taaatattta
    58081 ccatacatct atcttatcat aggattaggg cagattctta cctgtttgct aaaattcttc
    58141 tcatttgagt tcgaagtatt ttattttaat agataaactg ttattcttac atttggaata
    58201 ccaaagtagg ggagaggtgc ttgtgagtaa aattatgact gcgtatcata aaaatgaaag
    58261 attaaagaaa atagtggtta ttttgataac cggattgacc gctgcggtcg ctttaaatta
    58321 ttttttgatt ccagccaatg tcttttctgc agggatgaat gggatcgctc aaatcatttc
    58381 ctcgctttta tatgaatggt ttcatatcaa gatagacaca ggaacattta tttttctttt
    58441 gaatatccct gtgtttgtat tagggtttct caaagtagga aaacgagcaa cgatccttag
    58501 ttttgtgaat gttgtatgtg tatcggtgat gacgatgctg cttccagtcg gacagatcac
    58561 tgataatatt ttgatgaatg ccctagtagg cggtgtttta ttaggtcttg gcgtaggatt
    58621 atctttaaaa atgggcttta caactggtgg gatggatatc atctctcttg tactttcaca
    58681 aacaactgga aaaacagtcg gaaactacat gctgattcta aatggtatca ttgtagtcat
    58741 cgcaggcttc ttctttaact gggaaagtgc cttgtatacg attatttcca tttatgcaat
    58801 gactcaagta attgatgcca tccacacgag tcatcaaaaa gtaacagcaa tgatcgttac
    58861 cgtcaagcca gaagaggtaa cagaagaact agcaaaacgg atggtacgtg gaatgacatt
    58921 actgccgtct gtcggtggct attcaaaaaa acaagggaac atgatcatga tggtcatcac
    58981 ccgctacgaa atgtatgatc ttgatcagat cgttcatgaa atcgacgacg atgcatttat
    59041 caatatttta ccaactcatt cagtatttgg ccggtttgca aatgaaaacg aacaaaaaat
    59101 gtatcgaaca actggcgtat tgccagaaat aaaaaatcgt tcacaaaaaa aatgaggaat
    59161 caggtttatt ttagaataaa tttaatctat tacatctaat aagaacattt ttataaattt
    59221 aaacgagaat cttacttcta aattctcatt tacaagcagc taaaaaaaga gtatgataaa
    59281 taaaaatcgt gttaaggagt gtcgtacgat gagcgaagca aaccaagaac ggtctggaca
    59341 agaaatagaa ctaatcaaag aacgtattct tgctgccttg gaaatggtga ttgatcctga
    59401 attaggaatc gacatcgtca atttaggctt gatttatgat atagaattca atcctgaaaa
    59461 tggagaaaca gtcattaaga tgactctaac aactatgggc tgtccattag cagatatttt
    59521 aacagaatct atccatgacg cattaaaaga agtgccagaa gtaacgaaag cagaagtcaa
    59581 actagtctgg tatccagcat ggacgacaga taagatgagc cgttatgcac ggattgcgtt
    59641 ggggatacga tagaaatctt ggctgactag ctatgagaag caaataggaa aaacaaaaaa
    59701 gccttttatc ctttctagaa gaaaagagat aaaaggtttc tttgtttata aaattttgtc
    59761 tgctatatta taagttaatt aaataaatgt gttctattga taaaggacat tcaaatccct
    59821 ttccttttgg aatccttctt ttttacatca gtttgatttt cgtatagtat tctttctcat
    59881 cttcacgata aatcgcagcc ccattttttt gttgtgcttt aagactgcca agattttttt
    59941 tatttacaga caaaagtgcc tcatcaatgc cgattttttt tgcctcttgt agtactaatg
    60001 ctaatccttg tgtggcatat ccttttttac gataattagg ggagatgccg taaccaatat
    60061 ggccagcgcc gtttcttaat gtttcgttca gtttatggcg caaattaaaa attcctacat
    60121 actcatgttc atcactttct aaaataaaga cggttgcggg aacgtaactc tcaggaagat
    60181 cgattcctaa agacgttttt tcgcattttt ttacataatc taaaaattca gcaaatgtat
    60241 agccataagc attgttgata aatccactct catttggtcc aaagctagtt tgtagctgat
    60301 aagctttctt taaatctgct tcccatagtt tgatcagttt catcgtattc acctctttaa
    60361 gtaaccttat tcatttgttt tctactatag cactattgtt gtaaatagcc atgcctattt
    60421 ttatttattg tgtcatatcg tattaagaat catcgaacaa tacaaatatg aattacaata
    60481 aaaaaattat ttgaagttcg ttcattcgtt acttatgatc tctagaagaa agaaaacgtg
    60541 aattacttca gcgtctagaa ttccagaagg atagtaatca acagaagaaa taatcaatat
    60601 ccaaatgaaa gaagatagct gaatcgagaa aaagaggaaa aaagaaatga agaaaaaaat
    60661 aaaatagtta ctaatcccag agtcgttcgt ttaacattga aatcgatcat atggataaaa
    60721 cagatttttt caccaaccct caatagatga tggagttgct cggatgaatt atttgtgtag
    60781 atggcataag ggagggcgta cagaaatgaa aaagaacaaa aatatgttct tgacaaaaaa
    60841 cacatgtaat cctaaactaa aagatgtgat gcggctatgg cggaattggc agacgcgcta
    60901 gcttcaggcg ctagtgaggg tgacctcgtg gaagttcgag tcttcttagc cgcataattt
    60961 gtttttttat aaagagaagg tacacctgga gcgatgagaa agaaaataac atattatcta
    61021 aaagaatata ggaaaaattt taaacaacgg aaccagattc aaataaatca aaaaaaattt
    61081 gtgtgaaggt gggacagttt aaaacctaat agattgattc aaatagtaga tttatagatt
    61141 ctgatacaag aaatactggc aaacgatagt taaggaataa agactaaact taaactcaaa
    61201 aagaggtcat gcgaaagaat aaatcgcatg acctcttact atattttgaa tgtgtttaaa
    61261 cgttcaaata atgaatctta gtaccaaccg tttgcttccc agaatgcttt cgccgcttcc
    61321 caagaaccat aacgtgaagt aacatattgt tctgctactc tttcttggtt tgcagcagag
    61381 tagtcaccat ttaagtaaga agaatctaat tggtaacggc cgatgtaacg tccgttcgtt
    61441 gctgtgtaag aaccgcttga ttctttttgt gcgatccatt cttttgcaga gcttgtactt
    61501 gctggagtag cagcagtttc tgttacagca ggagcaggtt gtgtttcagc aacaggcgct
    61561 gcttgtgttt ccgtttgaac cgtttcttgt acaacaggtt gttcagcttg aacaggttca
    61621 gcttggactg gtgcttcttg aacggctgct tgaggttcag cagctgcttg tgcagagcct
    61681 tctgttggga ttgttaattg ttgtcctgag ta
//
LOCUS       DAYYEF010000009        61534 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000009 DAYYEF010000000
VERSION     DAYYEF010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 61534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.009"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(59..187)
                     /locus_tag="ACHA1B_000720"
     CDS             complement(59..187)
                     /locus_tag="ACHA1B_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFM8701509.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACHA1B_000721"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="ACHA1B_000721"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFM8701510.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="ACHA1B_000722"
     CDS             complement(1674..2729)
                     /locus_tag="ACHA1B_000722"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFM8701511.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACHA1B_000723"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="ACHA1B_000723"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016884 - carbon-nitrogen ligase activity,
                     with glutamine as amido-N-donor [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HFM8701512.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACHA1B_000724"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="ACHA1B_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HFM8701513.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACHA1B_000725"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="ACHA1B_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0030956 - glutamyl-tRNA(Gln)
                     amidotransferase complex [Evidence IEA];
                     GO_function: GO:0050567 - glutaminyl-tRNA synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA];
                     GO_process: GO:0006450 - regulation of translational
                     fidelity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HFM8701514.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACHA1B_000726"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="ACHA1B_000726"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003911 - DNA ligase (NAD+) activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HFM8701515.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACHA1B_000727"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="ACHA1B_000727"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006268 - DNA unwinding involved in DNA
                     replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HFM8701516.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="ACHA1B_000728"
     CDS             10491..12050
                     /locus_tag="ACHA1B_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HFM8701517.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="ACHA1B_000729"
     CDS             complement(12161..14092)
                     /locus_tag="ACHA1B_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022877 -
                     protein-N(PI)-phosphohistidine-fructose phosphotransferase
                     system transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-specific PTS transporter subunit EIIC"
                     /protein_id="HFM8701518.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACHA1B_000730"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="ACHA1B_000730"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008662 - 1-phosphofructokinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HFM8701519.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="ACHA1B_000731"
     CDS             complement(15021..15773)
                     /locus_tag="ACHA1B_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFM8701520.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="ACHA1B_000732"
     CDS             complement(15932..16141)
                     /locus_tag="ACHA1B_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701521.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="ACHA1B_000733"
     CDS             complement(16152..17480)
                     /locus_tag="ACHA1B_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701522.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="ACHA1B_000734"
     CDS             17616..17771
                     /locus_tag="ACHA1B_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPJ_0845 family protein"
                     /protein_id="HFM8701523.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACHA1B_000735"
     CDS             complement(17845..18432)
                     /gene="yihA"
                     /locus_tag="ACHA1B_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="HFM8701524.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACHA1B_000736"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="ACHA1B_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HFM8701525.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACHA1B_000737"
     CDS             complement(20012..21301)
                     /gene="tig"
                     /locus_tag="ACHA1B_000737"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005854 - nascent polypeptide-associated
                     complex [Evidence IEA];
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0015031 - protein transport [Evidence IEA];
                     GO_process: GO:0051083 - 'de novo' cotranslational protein
                     folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HFM8701526.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="ACHA1B_000738"
     CDS             complement(21455..22387)
                     /locus_tag="ACHA1B_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701527.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="ACHA1B_000739"
     CDS             complement(22544..23203)
                     /locus_tag="ACHA1B_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HFM8701528.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACHA1B_000740"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="ACHA1B_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HFM8701529.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="ACHA1B_000741"
     CDS             complement(24244..24534)
                     /locus_tag="ACHA1B_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701530.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="ACHA1B_000742"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="ACHA1B_000742"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004360 - glutamine-fructose-6-phosphate
                     transaminase (isomerizing) activity [Evidence IEA];
                     GO_process: GO:1901137 - carbohydrate derivative
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HFM8701531.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACHA1B_000743"
     CDS             complement(26821..28176)
                     /gene="glmM"
                     /locus_tag="ACHA1B_000743"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008966 - phosphoglucosamine mutase
                     activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HFM8701532.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="ACHA1B_000744"
     CDS             complement(28200..29369)
                     /locus_tag="ACHA1B_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdaR family protein"
                     /protein_id="HFM8701533.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACHA1B_000745"
     CDS             complement(29366..30253)
                     /gene="cdaA"
                     /locus_tag="ACHA1B_000745"
                     /EC_number="2.7.7.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004016 - adenylate cyclase activity
                     [Evidence IEA];
                     GO_process: GO:0006171 - cAMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diadenylate cyclase CdaA"
                     /protein_id="HFM8701534.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACHA1B_000746"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="ACHA1B_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016903 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HFM8701535.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="ACHA1B_000747"
     CDS             34320..34841
                     /locus_tag="ACHA1B_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HFM8701536.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="ACHA1B_000748"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="ACHA1B_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="ACHA1B_000749"
     CDS             complement(36284..36940)
                     /locus_tag="ACHA1B_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701537.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACHA1B_000750"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="ACHA1B_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0043937 - regulation of sporulation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HFM8701538.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACHA1B_000751"
     CDS             complement(38477..39475)
                     /gene="yvcK"
                     /locus_tag="ACHA1B_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HFM8701539.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACHA1B_000752"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="ACHA1B_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HFM8701540.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="ACHA1B_000753"
     CDS             complement(40491..41222)
                     /locus_tag="ACHA1B_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HFM8701541.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="ACHA1B_000754"
     CDS             complement(41226..42491)
                     /locus_tag="ACHA1B_000754"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HFM8701542.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACHA1B_000755"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="ACHA1B_000755"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HFM8701543.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACHA1B_000756"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="ACHA1B_000756"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009380 - excinuclease repair complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006289 - nucleotide-excision repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HFM8701544.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="ACHA1B_000757"
     CDS             47833..49335
                     /locus_tag="ACHA1B_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HFM8701545.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="ACHA1B_000758"
     CDS             49337..50074
                     /locus_tag="ACHA1B_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFM8701546.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACHA1B_000759"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="ACHA1B_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HFM8701547.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACHA1B_000760"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="ACHA1B_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HFM8701548.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACHA1B_000761"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="ACHA1B_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HFM8701549.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACHA1B_000762"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="ACHA1B_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HFM8701550.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACHA1B_000763"
     CDS             complement(55574..56740)
                     /gene="hemW"
                     /locus_tag="ACHA1B_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HFM8701551.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="ACHA1B_000764"
     CDS             complement(56756..56983)
                     /locus_tag="ACHA1B_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HFM8701552.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57303..57626)
                     /gene="relB"
                     /locus_tag="ACHA1B_000765"
     CDS             complement(57303..57626)
                     /gene="relB"
                     /locus_tag="ACHA1B_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB family
                     antitoxin"
                     /protein_id="HFM8701553.1"
                     /translation="MRFFKRGNYRAMITVRVSDAKKEWLSYMAEFYGITLSELLKNYS
                     MEQLEDEYNRQTAEIAHKHWIRSGKTTVFMEESLMNLVGWNDLPFKIHARNSEAALIG
                     KYVYW"
     gene            complement(57969..58415)
                     /locus_tag="ACHA1B_000766"
     CDS             complement(57969..58415)
                     /locus_tag="ACHA1B_000766"
                     /inference="COORDINATES: protein motif:HMM:NF013964.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HFM8701554.1"
                     /translation="MKIKIYNQEENQTRHIRNLSNAKLEEEARKVSNYNKKMAAKYVN
                     EEEFCFSKTKIYKRNPFVSEYVKRLAKGICQLCQEKGPFIKDGVPYLHCHHIEYLSQG
                     GKDVIENCIALCPNCHARIHELELPDDKEKLLKIVEKRENSFSKIP"
     gene            complement(58396..58992)
                     /locus_tag="ACHA1B_000767"
     CDS             complement(58396..58992)
                     /locus_tag="ACHA1B_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HFM8701555.1"
                     /translation="MNPTLITKKELLKKLDISTGVLANLIRNGMPKEGEMFNLDKIIT
                     WRENWSKNILGELEVGRVYTNKEISEKFKCSKQGGMRRSHQTNTLVLFSDQTGSNVYK
                     DKWLNGILQYTGMGLKGDQVLDKNQNKVLANSKSNFVKIHLFETFKPKEHTYLGEVYL
                     AGQIYTVNEKDSSGNSRKVYKFPLALINQEQLIEDKDI"
     gene            complement(59476..59637)
                     /locus_tag="ACHA1B_000768"
     CDS             complement(59476..59637)
                     /locus_tag="ACHA1B_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701556.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            complement(59630..60304)
                     /locus_tag="ACHA1B_000769"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="ACHA1B_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            60827..61434
                     /locus_tag="ACHA1B_000770"
                     /pseudo
     CDS             60827..61434
                     /locus_tag="ACHA1B_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313657.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_function: GO:0019172 - glyoxalase III activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase family
                     protein"
BASE COUNT        17077 a        13212 c        10646 g        20599 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccacacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 cttatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt cata
//
LOCUS       DAYYEF010000010        60440 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000010 DAYYEF010000000
VERSION     DAYYEF010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 60440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60440
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.010"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(21..251)
                     /locus_tag="ACHA1B_000771"
     CDS             complement(21..251)
                     /locus_tag="ACHA1B_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701557.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="ACHA1B_000772"
     CDS             complement(687..1253)
                     /locus_tag="ACHA1B_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM8701558.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="ACHA1B_000773"
     CDS             complement(1253..2209)
                     /locus_tag="ACHA1B_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HFM8701559.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="ACHA1B_000774"
     CDS             complement(2209..2865)
                     /locus_tag="ACHA1B_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HFM8701560.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="ACHA1B_000775"
     CDS             3235..5253
                     /locus_tag="ACHA1B_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFM8701561.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /gene="leuS"
                     /locus_tag="ACHA1B_000776"
     CDS             5680..8094
                     /gene="leuS"
                     /locus_tag="ACHA1B_000776"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HFM8701562.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="ACHA1B_000777"
     CDS             8442..9995
                     /locus_tag="ACHA1B_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WD40/YVTN/BNR-like repeat-containing protein"
                     /protein_id="HFM8701563.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="ACHA1B_000778"
     CDS             complement(10376..12160)
                     /locus_tag="ACHA1B_000778"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701564.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="ACHA1B_000779"
     CDS             complement(12175..13896)
                     /locus_tag="ACHA1B_000779"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701565.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="ACHA1B_000780"
     CDS             13996..14757
                     /locus_tag="ACHA1B_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFM8701566.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="ACHA1B_000781"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="ACHA1B_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..20065
                     /locus_tag="ACHA1B_000782"
     CDS             16664..20065
                     /locus_tag="ACHA1B_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFM8701567.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATPIEFEIERSQTAVVELTKE
                     NRLTPGGVVLTKIDDQSGEILQGAVFELQNREGETLQTGLTTGEDGKLAIDGLAPGAY
                     QLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGVVLTKIDDQSGEVLQG
                     AVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIE
                     RSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADG
                     KLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIR
                     GNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(20418..21266)
                     /locus_tag="ACHA1B_000783"
                     /pseudo
     CDS             complement(20418..21266)
                     /locus_tag="ACHA1B_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            21419..22531
                     /locus_tag="ACHA1B_000784"
     CDS             21419..22531
                     /locus_tag="ACHA1B_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFM8701568.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(22609..22902)
                     /locus_tag="ACHA1B_000785"
     CDS             complement(22609..22902)
                     /locus_tag="ACHA1B_000785"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_process: GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="HFM8701569.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            23070..23384
                     /locus_tag="ACHA1B_000786"
     CDS             23070..23384
                     /locus_tag="ACHA1B_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HFM8701570.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            23405..25384
                     /locus_tag="ACHA1B_000787"
     CDS             23405..25384
                     /locus_tag="ACHA1B_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFM8701571.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            25397..25723
                     /locus_tag="ACHA1B_000788"
     CDS             25397..25723
                     /locus_tag="ACHA1B_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HFM8701572.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            25739..26257
                     /locus_tag="ACHA1B_000789"
     CDS             25739..26257
                     /locus_tag="ACHA1B_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701573.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            26257..27609
                     /gene="celB"
                     /locus_tag="ACHA1B_000790"
     CDS             26257..27609
                     /gene="celB"
                     /locus_tag="ACHA1B_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFM8701574.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(27693..29198)
                     /locus_tag="ACHA1B_000791"
     CDS             complement(27693..29198)
                     /locus_tag="ACHA1B_000791"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HFM8701575.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(29290..29880)
                     /locus_tag="ACHA1B_000792"
     CDS             complement(29290..29880)
                     /locus_tag="ACHA1B_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFM8701576.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            30059..31705
                     /locus_tag="ACHA1B_000793"
     CDS             30059..31705
                     /locus_tag="ACHA1B_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis C-terminal
                     domain-containing protein"
                     /protein_id="HFM8701577.1"
                     /translation="MDNQRKPSLDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            31754..32473
                     /locus_tag="ACHA1B_000794"
     CDS             31754..32473
                     /locus_tag="ACHA1B_000794"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HFM8701578.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            32952..33899
                     /locus_tag="ACHA1B_000795"
     CDS             32952..33899
                     /locus_tag="ACHA1B_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8701579.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            33911..34831
                     /locus_tag="ACHA1B_000796"
     CDS             33911..34831
                     /locus_tag="ACHA1B_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8701580.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            34872..36329
                     /locus_tag="ACHA1B_000797"
     CDS             34872..36329
                     /locus_tag="ACHA1B_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8701581.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            36674..37288
                     /locus_tag="ACHA1B_000798"
     CDS             36674..37288
                     /locus_tag="ACHA1B_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFM8701582.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            37281..39005
                     /locus_tag="ACHA1B_000799"
     CDS             37281..39005
                     /locus_tag="ACHA1B_000799"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFM8701583.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            39002..40453
                     /locus_tag="ACHA1B_000800"
     CDS             39002..40453
                     /locus_tag="ACHA1B_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFM8701584.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(40926..43079)
                     /locus_tag="ACHA1B_000801"
     CDS             complement(40926..43079)
                     /locus_tag="ACHA1B_000801"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HFM8701585.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDSSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(43081..44127)
                     /locus_tag="ACHA1B_000802"
     CDS             complement(43081..44127)
                     /locus_tag="ACHA1B_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM8701586.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            44277..45566
                     /locus_tag="ACHA1B_000803"
     CDS             44277..45566
                     /locus_tag="ACHA1B_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HFM8701587.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            45579..48281
                     /locus_tag="ACHA1B_000804"
     CDS             45579..48281
                     /locus_tag="ACHA1B_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HFM8701588.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            48266..49123
                     /locus_tag="ACHA1B_000805"
     CDS             48266..49123
                     /locus_tag="ACHA1B_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFM8701589.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(49194..50051)
                     /locus_tag="ACHA1B_000806"
     CDS             complement(49194..50051)
                     /locus_tag="ACHA1B_000806"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFM8701590.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            50262..52433
                     /locus_tag="ACHA1B_000807"
     CDS             50262..52433
                     /locus_tag="ACHA1B_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFM8701591.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            52501..52842
                     /locus_tag="ACHA1B_000808"
     CDS             52501..52842
                     /locus_tag="ACHA1B_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFM8701592.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(53118..54872)
                     /locus_tag="ACHA1B_000809"
     CDS             complement(53118..54872)
                     /locus_tag="ACHA1B_000809"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701593.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(54883..55719)
                     /locus_tag="ACHA1B_000810"
     CDS             complement(54883..55719)
                     /locus_tag="ACHA1B_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFM8701594.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(55721..56404)
                     /locus_tag="ACHA1B_000811"
     CDS             complement(55721..56404)
                     /locus_tag="ACHA1B_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HFM8701595.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            complement(56563..57957)
                     /gene="uxaC"
                     /locus_tag="ACHA1B_000812"
     CDS             complement(56563..57957)
                     /gene="uxaC"
                     /locus_tag="ACHA1B_000812"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFM8701596.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            complement(57996..59495)
                     /locus_tag="ACHA1B_000813"
     CDS             complement(57996..59495)
                     /locus_tag="ACHA1B_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HFM8701597.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            complement(59488..>60440)
                     /locus_tag="ACHA1B_000814"
     CDS             complement(59488..>60440)
                     /locus_tag="ACHA1B_000814"
                     /EC_number="1.1.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFM8701598.1"
                     /translation="AGFTIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENV
                     FCCSLVDRIVPGYPREDAGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQA
                     GLNVIITDDMTPYRERKVHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFN
                     LELIPMLSLPKDELAIYADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIE
                     EQNQVPPLITVSLAALLLMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALW
                     GEDLSQIPNVTDTVQEIAAKIDQKGVRSVLQEMKGTMVHA"
BASE COUNT        19452 a        10807 c        12249 g        17932 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggtttaac
    18901 tacaggagaa gatggaaaac tggcaattga cggtttagca ccaggagcat atcagctggt
    18961 agaaactcaa gcgccaatag ggtatgaatt agatgcgaca ccaatcgagt ttgagatcga
    19021 aagaagtcag acagcggtgg tagaattgac gaaagaaaac cgacttacac caggcggtgt
    19081 cgtgttgaca aagatcgatg accaaagcgg ggaaatcctg caaggagctg tttttgagtt
    19141 acagaaccga gaaggagaaa cgctacaaac cggtctaact acaggagaag atggaaaact
    19201 ggcaattgac ggtttagcac caggagcata tcagctggta gaaactcaag cgccaacggg
    19261 gtatgaatta gatgcgacac cgatcgagtt tgagatcgaa agaagtcaga cagcggtggt
    19321 agaattgacg aaagcaaacc gacttacacc aggcggtgtc gtgttgacaa agatcgatga
    19381 ccaaagcggg gaagtcctgc aaggagctgt ttttgagtta caagatgcca atggaaccgt
    19441 tctgcagtca ggtctaacca caggagcaga tggaaaactg gcgattgacg gcttagcacc
    19501 aggagtgtat cagctggtag aaacccaagc gccaacgggg tatgaattgg atgcgacacc
    19561 aatcgagttt gagatcgaaa gaagtcagac agcggtggta gaattgacga aagaaaatcg
    19621 acttacacca ggcggtgtcg tgttgacaaa gatcgatgac caaagcggag aagtcctgca
    19681 aggagctgtt tttgagttac aagatgccaa tggaaccgtt ctgcagtcag gtctaaccac
    19741 aggagcagat ggaaaactgg cgatagatgg cttagcacca ggagcatatc agctggtaga
    19801 aactcaagcg ccaacggggt atgaattgga tgcgacacca gtaactttca agatcgaaaa
    19861 agaacaagaa gtggcgatct ttttaacaaa agagaataga aaagttgctg atagctcaga
    19921 tataagagga aacaatccaa caagcagtgg aaataagcat cttccaaaaa ctggagaaac
    19981 catcattagc cagtttatat tgtcaatatt gggtgtgcta cttgttttca tcagtataaa
    20041 atttagaaag aaacgaaata tatgagctaa aataaaaaat tgaataagca tagtttttaa
    20101 aatcaactag tacccatcaa ttgaatggaa actaccgatt ttagaagggg tatacaaaca
    20161 aatattagta tcggagtaga gaaggttgaa cccaaccagt aaataagtaa agacaatttt
    20221 gtgctgcgtt gagaagtgaa aaataaacct ttgtagtaat actagttaat aaaaaatata
    20281 caaaaacact gcgaaaatca ttcttgagtt tcgcagtgtt ttttgcctaa tgactcaagt
    20341 ttattgggta atactttgat tttctttcta caaataatca gcgatcagtt gtaatttttt
    20401 ctctagtttt aatggctctt tgtcaataag gagaaaaaca agtcgggtct tttgtctcgg
    20461 aaagcttcaa ccaactcgtg aataaaggtt acgcctcctt gaaaggcgtg gaaaaaccaa
    20521 gtaatcgatc aatcaccaat ttcgcatttg gtagaacatg tttggtgagc tgaaagtagg
    20581 tggcgttcat gtctgtaact aagaattcta tttctttagg attagtgcag ctaaggaaat
    20641 agtttgttaa tcgaggaatt ttttgtgtag gtaaattttc tcgattaatt tttctgtctc
    20701 gccatccgcg gaaataaaac tcagtttatc ctcaacggaa acgtgagaac gaaattcaca
    20761 accctcaaca ctcaagacag aattcttttg gaagactttg gtaaatagct tctcaactct
    20821 ttcaatgtgc gaataacggt tgtcaaagat acctaacaac ttttcgaaat aaaaaataac
    20881 gacacttttt cagtcagtaa agaagtgatt ttatgtctga catgatttga aatcgagtgc
    20941 cttggacgga taaaataact ttgagcgttc caatggcttc gacagttttt acaggtatag
    21001 cgctgctttt ttaggcgtat aaccattggc atatgattat attattcaaa gtggacaatg
    21061 gtttccttct tcttgttttt caccaccatt aatttcctat ttccatctac cacagcagaa
    21121 ccacaatttc tacagacaca tggagcaggg aagagaactg cagcaacgat caatgttttt
    21181 ttcttctgta aggtttcgta agagacctct gtaatcatca aatttttgtc tattgatctc
    21241 agaatttttt tgatagaacc attcataaag catatcgttc tctcagttgt ttattttgtg
    21301 gtgatttaat catacaagaa aacgatatgt ttttttataa aaacatgaat aggaaaaata
    21361 gttgacaaga aaatgacaac gccatatgat gttccatagt atttacaacc tgtcatagat
    21421 gactgtaaaa aataaaagta aaaagaaagg acgacaacag gtggattttt atcagtctct
    21481 acaactagat ccgtttattt taaaacaaaa aatacgagaa gcagcttcta aaaaagaaaa
    21541 gtgcatgtat atttgttcat tgtttttacg atcattattc atcgtattgt ttgccatttg
    21601 ttttatcatt ataattacaa cattatttga atcgaagcat aaaccatacg ctgtggtttt
    21661 attctgtatg ttgatgagta ttcgttttgt tgactttggt tataagattt cccattcgat
    21721 cataggttta gcaatcgtca tgttctcact attagtagca ccgtatgtcc agctgatcaa
    21781 atggtcagtt atgggcatgt tgattcattt tattttacta agcagcatat taatggcaac
    21841 cgctagtgat cccaaaatgg ggaatgcttc tttgtacggc ttttcatatc tctttattgt
    21901 ttattcgtta cctaaagatt cgttgaacaa gaatttcttt acacaaacaa gtagcttatt
    21961 atttttgttt ttttgttggt tttcagttct cctttacaga aaacatcgag aaaagaacaa
    22021 agacaaaagc ttgtttaaag agattttttt gaaaggcatg tattcgcagg aaaaaatttg
    22081 gatgctcatc tatgcatttg gcattagtct tttgatcgtt gcaggagagt atgtcccttt
    22141 tcagcgattg atgtgggcag ggtttgcatt ttcttctatt gtatctagct atggattgat
    22201 gtcgattggt ttcaaagaac gagcagtaga ccgaatcatt ggctcattga ttggatgtgt
    22261 tttatttatt ggtatcagcc aatttattcc ttttaactgg gtcggtatat taggtggtct
    22321 agctttaggt gtttgttcta cctatagata taaaacagtt tttaattctt ttggtgcttt
    22381 ggcaatcact gccagtttat tcggggttcc aggagcagta acgatccgca tttttgagaa
    22441 tatccttggg gtatgtttag gaatcatgta tattggggtg actgaaatac ttatccgaaa
    22501 aataagagaa aaacacggtt tgaatcatta gatgagatcg aataaaaaat aaggaaaaag
    22561 tgaagataca catggatgat aaattgctat cattccatgt gtatcttttt acggtaaatc
    22621 agtgaaacgt tcgactttca tttttaattt atacttttta cggagttcgt ttatttgagc
    22681 catcatttcg gatttgtgat gcttttcgat tgcttcttca tctttccaac ggtcgatcag
    22741 taaaagagat tctggatctt ctagtggaaa gtaatagtca tatttctcgt ttccttcttc
    22801 tgcacgaatc gctttgacaa tgtttctttc gaccatttct tctgcaaatt ttctggcttg
    22861 tccatttgta cttgtataca aaatattcac tgtgatactc actaaatccc ctcctgaaaa
    22921 aattctatca ctagtatatc acggtgccag aaattattat tcaagatatg atacacattt
    22981 tttccgcaat gctacggaaa tatatatttt gaatagaaaa cgcttacaag atatgcttgg
    23041 tttataaaaa taaaaggagt gattgattta tgaaaaaagc attgattatt tgtgcggcag
    23101 gaatgtcatc ctcgatgatg gcctcaaaga caacggattt ctttaagcaa aaaagagaag
    23161 aggtactcgt agatgcagtt tcagctacag aaggcgataa tatgattaag aatagtgatt
    23221 ttgatttatt tctgatcagc ccgcaaacga cgatgttttt ggataaattc aaaaaattag
    23281 gagaatctgt tggaaagcct gttgttagta tccctttcca agcgtatgtc ccaatcccta
    23341 caggcatcca gaagttagca gaggtgatcg aagagaacat atgatggaat aggagtggat
    23401 gataatgaaa cagaaggaaa aattgctgtt gagatatttg attgatcaca agaaggagta
    23461 tgtcaccagt caacgtttag cttctgaatt gttattatct gatcggacaa tccgtaatta
    23521 cttgcagcgg atcaaagagt tagtagaaaa aaacggaggt aagatcattg ctaaaccagg
    23581 ttatggctac caactgcata ttttacaaag actgacattt gacttgtttt tgagtcggca
    23641 agaaatagta cctggatatg ctagagaacc gcaaggattt tatgagtccg aagatcgaca
    23701 aaagtatata ttgaaccaat tgcttttgga agatgccatt ctttttatgg atgatttggc
    23761 agaagagctt tatatcagtc gttccagttt gacaaaggac atgcaagaaa tcaaggagcg
    23821 attgattcca tattcactaa aaatcgtttc taagcatggt caagggacat ggatcgaagg
    23881 ggaagaaaga aatcgacggc attttatcat ggatactttt tttggaaacc attatggaaa
    23941 ttcattgaaa gaatatttag ggcaaagccg ttttttccca gacatcagtt ttgaagagct
    24001 agtcattatc attctcgatg aaacaagaga agctaagtta aaagtttcgg attttatcat
    24061 acagaatctg actttacact tggctttggg gatcaaacgg ctccgagaag ggtttgaaat
    24121 caaggaatta ggcatcgaac aagaagtttc taagcgagta gagtatcaag tggcgcagcg
    24181 gatcgttcaa cgtattgagg taatcgcagg tgtatcgttt cccgaagaag aaattgctta
    24241 tttgacatta catctcatgg ctaagtcgaa tcacaaagaa aatcaaaatg atcaggaact
    24301 atcaaaggaa ttagcgaaag ttctgaaaag attgtctcag gaatttcatt tttcattagt
    24361 agaggatctc cagcttttca atggactact cgatcatttg tcaccgatga tgattcgatt
    24421 gagccgaggt attcgcattg agaacccatt gactgaggag ataaagaaag aaaatcccaa
    24481 agtctttgac gcagtaaaaa ggcatttcag caacatgccg gctttgaaaa actataccat
    24541 caatgaagat gaatgggcct atttggcttt gcatctcatg gcggcattgg aaaaagaaag
    24601 agctgcgcat aaactacatg cattgattat ctgtgcaacg ggttacggca gtgcccaact
    24661 attaaagaat cgcgtagtca gtgaattcgg taaaaatatt acagtggtaa gtgtaaaagg
    24721 ctattatgag atcaatgaaa caactttaaa aggaatcgac ctgattattt cttctattga
    24781 tctttcgaca atgtttttca aaattccagt tttacatgtc agtatttttt tgaatgaaga
    24841 tgatgttcgt aaaatacgaa aggtagttgg agaatctata ccctatcatt cctcagatag
    24901 accgatacca gcattttctc tacagcaaaa aaagcagatt tacaccgaac agttgtctga
    24961 aaaatttttc aagacttata cgtacgaacc gaaaaaggaa gaaattcttc atgatttgct
    25021 gcaaaagctg agcataaatg aagaagaagg atatataaga gaaatgcgaa agcagatcca
    25081 gcaacgtgaa aatatgggac aaatcatatt cagtgataca gtggcagtcc cacatcccgc
    25141 tgttccagtt ggaatcgaaa caaaggtagc cgttgcattg attccttctg ggatgcagtg
    25201 ggatcaatat caagaaattc attttgtttt tttagtttcg ccttcttatg tcgaaaatga
    25261 aggaattacg gtcgtgacta aagcaatcgt taggttagtt gaccagctaa aagtacagca
    25321 ggaaatctta gctgaaccta tttttgagaa tttcagcagt aaatttatca aactgatcga
    25381 ataaggagga aaacagatgg ctgaaaaaat aaacagtgaa acactacaag tgacttcttt
    25441 tgatatcatt ttccatagcg gaaatgcacg gacactgata catgaagcat ttcgctcgat
    25501 gcgtaaagag atgtttgaag aagtagaaga gaagttgcga caagcaaatg aagagattct
    25561 tcatgcgcat cagtcacaaa ctcaacttct gaaagaatat gccagcggga caaaaataga
    25621 aatggaaatt atcatggtcc atgcacaaga tcatctgatg acgacgatga cattattgga
    25681 agttgcacag gaaatgaatt atttgtatca aaaaaataaa tagaaaggaa ggatcattgt
    25741 gcaggataca gtaaaaagga aaatcgaatt agaaaaaaag caacttagtt tgaaaaacat
    25801 gtatttcaat cgttatctaa tcgtacgtta cctgactgcc tttttctttt tcatgaacat
    25861 gcaatggatg attctgcttc tatcagctaa aagtttagga agtagtttac cgatgattct
    25921 gattttagct attttgcctg cagtaggaga acaagtaaag ctttatcgaa aacaccaaac
    25981 gaacgttcca tggacaaagt ggtatttttt gttccagagt gtctttaatt tattagtgat
    26041 tccagtgttg tttacctcag gatttacatt cttgtatcct tttatggcaa ataacaatgg
    26101 aggacagtta tttgttttca ttcttgttgt aagcggtatt tttgccagtg catttataca
    26161 gtatcgttta aagaaaattt cactcaacca agaccaacag tatatccgta ttaaacaata
    26221 tgaaaaagcg ttatatttag gaaaggagaa taactaatgt ttgatttttt gcagaaatac
    26281 ctgatgggac ctatggggaa aattgcgcaa cttaaaatcg ttcgggctgt catggcagcg
    26341 gggatggctt ctattccttt cacgattgta ggctcgatgt ttttggtttt aaatattttg
    26401 ccattaccgt tcccattttt agaaggattt tttaatgcaa cttttttcaa agttagtgac
    26461 ttgtacatga tcgtcaatac aatgacgatg gggattttat ctatttactt tgccattgtg
    26521 tttgcttatg aattaacgtc aattgaacga gatgaacaaa aattaaatgt taatccgctc
    26581 acgggggcat tactatctgt ttttgcattc tttatgtgta tccctgaatt gatcatgact
    26641 gatggtaaaa tcagcttgat tgcttctatc aatgagacag aaactgtagt aaatggtatt
    26701 aggatgggct cttttgtcga acgtttagga acttcaggaa tctttacagc tattattatg
    26761 tcgattattg cggtcgaatt gtattgtatg tgtgtcaaga gaaattgggt cataaaaatg
    26821 ccagatgttg ttccgccagg agtttctcgt tctttcactg ctctgatccc aacatttgtc
    26881 attgcgtttg tggtgatgat catcaatgga ttattagttg cactaggaac ggatatcttc
    26941 aaaatgattg ctatcccatt tgggtttgtt acgcagttga cgaatacatg gcttggtgtc
    27001 atggtgattt atttcttgat ccatgcattg tggatcgtag ggatccatgg agcgaatatc
    27061 atcacttctt tcttgacccc gatcgtatta gctaatatgg cagctaacgc acaaggcgca
    27121 aattatccgt tggcaggaga attcaacaat tcttatgtaa ccgttggtgg atcaggtgcg
    27181 actttaggat tgatcatctt tattgcattc ctcgcgaaat ctgatcagct gaaagtgtta
    27241 ggaaaagcct cacttgtacc aggattattc aatatcaatg aaccaatcat tttcgggatg
    27301 ccaatcgtct acaatcccta tttagcggtt ccgtttttct tagctccgat ggcttctgct
    27361 acactcgctt attttgccat tcggctggaa atcgtcaaac cgatgcttgc acagatgccg
    27421 tggccttcac cagtcgggat cggagcattt gttggtagtg gtggtgattg gaaagctgct
    27481 gtgttagcag tcatttgtgc aatcatcgca ttcattatct ggttcccatt tatcaaattc
    27541 tatgataata aattattaaa tgaagaaaga gaaaaggcag cagaattagc tagtgaaaag
    27601 ttaaaatgat ttctaagaaa aaaggaactg tgacaaaaaa tcacagtccc tttttttctt
    27661 agaaatggga aaccactagt atataaatac cattattctt caatcaaccg cttcacgatt
    27721 gcataatccc cttcataagg ttcatctaca ccattgattt tttgataggg atccacgcct
    27781 tttcccgcaa taacgactga atcttgcgga gcgctttctg ctaaagcgcg tcgaatcgct
    27841 tcaggacgat ccatttcata atgaacgatc aaatctggat tagtaattgc ttcattgatt
    27901 tcttccgcga tttttttcgg atcttcaaat gctgggtcat ctgccgtcaa aaaggcgatg
    27961 tcagctgttt ctgatagcac ttttccaaaa tcatgtcgac gggagattgc tttgtttcct
    28021 gggctgccta atacaacaat tacacggcca tctggatgtt catttttggc aaatttcagc
    28081 aatgttttca agcttagata attatgtgca tagtccacat agacatgcgc tccattggat
    28141 tggatcaatt gatccattcg gcctggtaca cgagcttctt ttaatccgtc ttgtgcatct
    28201 tgactggagg cacctgttag tgctgcggca atgatcgcac tggctgcatt ttcttggttg
    28261 aatcctccag ccagcaaaat atcataagca gtatcgcaga tagctaagcg atcttcatga
    28321 gaagataaag taaaaccgtg agtaccttta tctgaacgga tcacttgata attgctttct
    28381 tccgaacgac cataagtgat cgttggaatc tggaatagat cggctgtttc cctaagtaaa
    28441 tcaaaatagt cactttcatg atttaaaaca actgtttttg aattcaagat caattgtcgc
    28501 ttgcaataga aatagtcatc aaatgtcgga tgttcgatcg gactgatatg gtcaggcgag
    28561 atattcaaga agattccgac atctaaagtc aagccgtata cgcgttgtgt tttgtaagct
    28621 tgtgaagaaa cttccatcac tagatgagtc ataccatttt caactgcttc tgacatcata
    28681 cgatataaat ctaatgactc aggcgttgtc aaatgggatt tgaaatatgt tttgccatct
    28741 aacgttgtat tcatagtaga aagcaatgct gtttttttat ttgttgtgtg atccaagatt
    28801 gcttttgtaa agtacgcagc agttgtttta ccttttgttc cagtgaatcc gatcactttc
    28861 aatttatttt gcggatagtc gtaaaaagcc atagcaagaa gcgccattgc tttacggata
    28921 tccgttacga tgattcctac tgctgaattt tcgtatggtt gttctgatac ataatattga
    28981 ataccctgtt cgattgctga atccaaatat tcttctttga aattcattcc tttacagaaa
    29041 aacaaagtag aagcatcagc ttttcttgaa tcataactta actgaagaaa ttcagctttt
    29101 tctggtacat caagatgcca gcctcttgtt gaaacaaatt cttttaatag attttctttt
    29161 aatagtaaat gacggatgtc ttctaaagag aagctcattg attgatccct cgctttattc
    29221 aatttcttgg tttattatag cacactcttt ttaatatatc gtttgtttcc gctatgacaa
    29281 aatccagctt tattcaaatt ttcttgacac aggggacaag cggatgagta ttttcataaa
    29341 caatgaactg actgtaatag ataggagaac gaatagtgtc tccaacaatc caaaaacata
    29401 ataattcaaa aagacgataa gactattggt aagtaaaagt ccttgcggca ttggaagccg
    29461 aaaaaatttg tggaaaataa tcggcggtat cgttataccg ccatttgagg ccccgactgt
    29521 gtacaatgtg taaaccccaa gactgaacaa aagacttcct gaaatcagtg aaaagaaatg
    29581 tgaggagatc atttccactt ttggaacaat ctctaaaaca acaggaaaaa gcagacttcc
    29641 cgctacagtc ttaaaaaata ctgattttcc taataggaca gcggctagaa gcagcatcat
    29701 aagattgatg ctccaaacag taactgagcg ttggatagaa aaggccgttt caactaaatg
    29761 tccgatggcg cccactccgg cggaagctat atcgtgaggg agcaagaacc aattcaatcc
    29821 aactgtgata aagaaaagac ctaaaaatat aacgggtagt ttttttattt cttgtgtcat
    29881 tgatatctcc tataaatgtt agccataaaa ggctgtatat ttctttactt taccaaaaaa
    29941 acgaaaccga attcaaaaaa acaattgttc ttataaaagt tatataaaat cgattgccag
    30001 tttctgtttt accaattaaa atgatagtaa tgttttgtag aaagttggaa tctgaccgat
    30061 ggataatcaa agaaaaccat cattagatca attaacaccg caagaaaaaa tggcacgagg
    30121 ctctgcttgg atgaccgcca gtaatatcat ttcaagattg ctaggcgctg tctatatcat
    30181 tccctggtat gcttggatgg gcgaaaatgc taaggctgcc aatggattat tcaatatggg
    30241 atacaatata tatgcattgt ttctactgat ctctacagca ggaatacctg ctgcgattgc
    30301 aaaacaaact gcacgctata attcattgaa tgaatatggc acttcacgac gattatttat
    30361 ccgtgcatta cagatgatgg gcgggttagg cctgttgttt gctttgttca tgtacatcgc
    30421 ctctccttgg ctagctcatg cttctggtgg cggagaagaa ctgattccaa cgatgcgttc
    30481 tttgagtatc gctgtattgg tttttccttg tatgagtgtg atacgagggt atttgcaagg
    30541 caatcaagaa atgatgcctt atgcgctgtc gcagattgta gaacaggtgg cacgtatttt
    30601 ttatatgcta ttggctacat tcatcatcat gaaagtcatg gatggtgact atgtgacggc
    30661 ggtcacgcaa tcaactttcg cggcatttat cggtatgcta gcaagtattc ttgtcctttt
    30721 gtattttttg aagaaacatc aagcgtatac atcggcgttt attcactaca gcgaaaacaa
    30781 aataaatatt gcaacgaagg aattgttgtt agataccgtt aaagaagcga ttccgtttat
    30841 tattgtgggt tcaggggtaa cgatcttcaa attagtcgat cagttcactt ttatgaagat
    30901 catgtctgca tccaccgagt attccaatgc acagttactg gatctttttt cgatttttag
    30961 tgccaatcca gataagttga cgatggtagt tattgcattg gcaacatcga tcgcgtctac
    31021 tgggttaccg ttgattacag aagctgttac gttgaaagat cgagtaggtc tggcaaaatt
    31081 gacaagcgga aatttacagt tgttttcatt ttttatgttt ccggcgacat ttggtgttat
    31141 gttacttgcc tatccgctaa atacattatt ttatacaccg gattctctag gaagtaatgt
    31201 actgatccaa gcaagttttg taggactctt cctaggacta tatatgctag tttccaacat
    31261 gctgcaagga atgtttgaaa acaaggcggc aattaattat ttggttattg ggtttctagt
    31321 gaaactcctt cttcaatacc cagccattcg tttatttgaa gtatacggcc ctttattggc
    31381 gacaatgatc ggatttgctg tgtcttgtac cttgatctta aagagaatcc atgaagtagc
    31441 ccgctttaaa ccaagttttg tctggcgcag gacattgctg atctttattc ttaccttgat
    31501 tatgcttttg gcttcgtgga tcacaaagat gatttttggt gcttttttaa acgaagatag
    31561 caaattccag tctctattgt tgattcttgt agtagcaggt ataggggctt tagtgtatgg
    31621 ttatttagct ttgaaaatcc gcttggcaga aagactacta ggaccaggaa tagcgcgttt
    31681 acgacataaa ttaaaaataa aataagtgaa tcagaagagc tagattgatg ctcttttgaa
    31741 atgggggaaa cgcatgcgtt tagataagtt tttagcagat atgggacttg gcagccgcaa
    31801 agaagtcaaa ggattaatca aaaaaggaac gatcgaagtc aatggacaag tggtgaaaag
    31861 cgataaagcg caagtaaatg aattcgaaga tgcggttact tatttaggag aaatcattac
    31921 gtatcaaaaa gatttttact acattttgca taaacctgca ggagtcattt ctgctactca
    31981 ggataatcat gatcaaaccg taatcgattt attggaagac caggattatc gggaagatct
    32041 ttttccagtc ggccgattag ataaagacac agagggcctc ttgattttaa cgaatgacgg
    32101 ggtgtttgcc catcagttac tatcacctaa aaaacatgtg gagaaagaat atctagctga
    32161 ggttagcggt ataatgacag aagaagatat ccgtttattt gcagaaggac tgattattga
    32221 tggcgatgag cagacattgc cggcaaaact ccaaattgat caagtagatc aagagacaga
    32281 aacttcaatt atccgtctga ttttgcatga aggaaagttt caccaagtta agcgaatggt
    32341 caaagcagta ggaaaagaag tcttatattt aaaaagaatc cgtatgggaa aattttggct
    32401 gcctaaagat ttgaataaag ggcaatatcg acccatgacc aaagaagagc tagaacaagt
    32461 gagagaaaaa taattgaatg gatagctaaa agaataagca gagtagttgt agcgccatct
    32521 gaaaagcaga cttgtccgtc tgactttcgg atggcttttt tgtgaaattt cggcttattt
    32581 ccgtagaagc tacttctgga acaccgtttg ttcggaataa gggactgtga caagactttt
    32641 gttacagtcc ccattgttcc ttgtgactca gagttagata gtaaggacac gatctcccta
    32701 atactcaggc caaaacgctg aattcacaac ctctgataaa cggtgttcaa tcagctgacc
    32761 ctcggtatta gctcaaaaaa cggcaaaata tgaggaacta ttttcccgtt tttttctcta
    32821 atactcaggc caaaacgctg atttcacaac ctctcctata ctttgtttca ttttccctat
    32881 actttgttta tttattctca ttattgaaag cgctataatt acgttgcgaa tgaatcgaaa
    32941 ggggttttta gatgaaaaaa cgaaaggggt tcaatcattt ttttatgaat ctatggcgtt
    33001 ataaagcact tgtcctgatg gctgtaccgg gtatgctttg gatgattttt ttcttttaca
    33061 tacctgtaat ggcgaatgtc gtagcattca aaaattttca tatttcagca gatgggttct
    33121 tggctagctt gagggaaagt ccttgggtgg gttgggaaaa tttcaaattt ttattttctt
    33181 cggatcaagc atttctcatc actaaaaata caattttata taatgtagca tttatccttt
    33241 tgaatctgct gatctcagtc gtatttgcaa tcattatgag cgagttgaga aataaacgac
    33301 tcgttaaagt ttatcaaacg atgtccttac taccttattt tctatcttgg gtcattatca
    33361 gttactttgt ttacgctttt ttaagtcctg acaaaggaat attcaatcag tggatcactg
    33421 gacatggagg agaagctgtc aattggtata atgaaccgaa atattggccg tttatcttgg
    33481 tgttcattgg tacatggaaa gggattggtt ataacagcat tatttacttt gcatctgtta
    33541 tgggaatcga tccgacttat tatgaagctg ctatggttga tggagctagc aaatggcagc
    33601 agatcaaaca tgtgacgata ccacaactta ttccactaat gacgatttta acgattttag
    33661 ccgtaggaaa cattttccga gctgattttg gcctgtttta taacattcct aggaattccg
    33721 gtgcattata tgatgtgact caagttttgg atacgtatat ctacaatggc ctgacatcca
    33781 caggagattt tggtatgacg gctgctgcag gactttacca atcagttgtc ggctttgtct
    33841 tgttgatgat cacaaatacg atcgcccgac gttttgatag cgattctgca ttattctaag
    33901 gaggaaaaaa atgaaaaaaa agaaagtgga gagagtccaa gtccgctctt tcaataagac
    33961 ggctaatttt ttctctaata taatgattgc actctttgct atttcctgta ttttgccatt
    34021 tatatttgtt atcgccatct cttttaccga tgagtccata ttgtcgactc acgggtacag
    34081 tttttggcca gaaaagttca gtatatttgg ttatacgtac ttgttcgacc agatgcagga
    34141 taaaattttc caagcgcttt tcgtcactgt acttgttact gttttaggta cactgatcaa
    34201 tagcacggct acttctttat atgcttatgc gatttcacgg tcaaactttc cattccgtcg
    34261 tttttttacc gttttttgtt tgattacgat gttgttctca ccagggatgg tggccaatta
    34321 tcttgttatg acaaatcttc ttcagttaaa agatacgatt tgggcattga tcttgccaat
    34381 ggctgtcagt cccttcaata ttattgtgat gcgcacattc tttaaacgtt cggtctctga
    34441 ttcgattatt gaatcggcac ggatcgatgg agctagcgaa ctgcgaatat ttgttcagat
    34501 cgttttaccg ttagctgttc caggtattgc gacaatcagt ttatttgccg cattgggtta
    34561 ctggaatgac tggttcaatg ctttactata catccaagat gataagctag ttccactaca
    34621 gtatcttttg atgaaaatcc aaagtaatat tcaatatctg acacaaaatt caggagcagg
    34681 aagccaattg acaggcggat tagcctcagt tccaggagaa tctgccagaa tggcgatcgt
    34741 agtcatctcg acgttgccta ttgcgatcag ctatccattt ttccagaagc attttgtcaa
    34801 aggtctaaca atcggcggag taaaagaata aagaaacaaa aatataaatc ataaaattag
    34861 gaggaagaaa aatgaagtta tggaagaaac tagcctttac aggtgtttca gcgttgttgt
    34921 tgggaacatt agcagcatgc ggaggttctg gttctaaaga ccaggcagaa gctagcaatt
    34981 cggacacttt gcagatgtat caaatcggag ataaaccaga taatttcgat caattgatgg
    35041 aagtagcaaa caaacgaatc gaaaaagaga tcggtgtaaa agtcaatatc aattacattg
    35101 gctggggcga ttacgaaaag aaaatgaacg tcatcatttc ttccggggaa aattatgata
    35161 tcgcctttgc gaacaactat gtttccaatg cccaaaaagg agcctttgct gatttgactg
    35221 aattagcgcc taagtacgct gaaaaagctt ataatgattt agatgaagca tatattaaag
    35281 gaaatctggt caatggaaaa ttatatgctt tcccagtcaa tggaaatgtc tttgctcaac
    35341 aagtacttac ttttaacaaa gctttactag ataaatacga tctttcaatt gatggaatcc
    35401 aatcttacgc tgatgcagaa aaagtcttga aggaattcca tgaaaaagaa ccaaacacgg
    35461 cagcttttgc cattggacaa ggcttcaaag tccaagggaa ctttgattat cctttaggga
    35521 atacgttacc atttgctatt gatctggatg gagatgattc gaaaatcatc aaccaatacg
    35581 ataatgaaac gtatatcgga ctgttacgta caatgcatag ctggtacaaa caaggactca
    35641 ttccaagtga cgctgcaacg agcaataagg attatccact agaaggaaat acttggctaa
    35701 tgcgtggaga aacacaagga ccgtatgatt atggcgatac aattttgaca aatgcagcaa
    35761 aacaagaact tgtctcaaaa gcaattactg ttccactaaa atctacagct caagcacaaa
    35821 tggcaaattt tgtcgtatca aatacttcaa aaaataaaga aaaatcagta gaacttctag
    35881 ggctgcttaa cagtgatcca gaattattga atgggcttgt ttgggggatc gagggagaag
    35941 catgggaaaa agtcgatggt tcagatgata aaatcaaatt gctagatggt tatcagccaa
    36001 atacacatat gtctgcttgg aatacaggaa acaacaagat tctatataca caagagtcta
    36061 ttacggatga catgattgcc aaacgtgatc aatcgattgc tgatgcagaa acttcaccga
    36121 ttttaggatt cagcttcaac actgacagtg tcaaaacaga attaagtaat atttctaatg
    36181 tcatgaatca atatttagat ggattgaata cagggactgt tgatccagat gaaacattac
    36241 cgaaattgaa agacgctttg gacaaggctg gctatgataa ggtattgaaa gaaatgcaaa
    36301 aacaatatga tgagttccga caagaataat aatgaataaa gacaaagggg ttgtgacaaa
    36361 agacgtgtca caacctcttg ttccgaataa acggtgttca aaagccagtt tctcggtatt
    36421 aagctaaata tatgtaaaaa tgtggaaagc catattcaca aaatttttct tactactcga
    36481 aactaagcgg ctatttcaca aactcttggt aaacggtgtt caatcagcta accctcggta
    36541 ttcgctcaca aaacgacaaa atatgaggaa ctatttttcc gtttgtttct ctaataatca
    36601 ggtcaaggtg ctgattgccc aacctttttt tgtataatga gaaagtataa acttaatgtt
    36661 tggaggagaa gatatgttag ggaaggtttt ggaagagtta tttatccgga tctgggtcat
    36721 tataaaacta accttgtatt tctggatata tacatttgcc ggcgggatca tctttggatt
    36781 aggtgcggca tggaaaacag tcaatgaact attttatttg tacggattcg agtataaaga
    36841 aatcacaata aaaagaggct ggaatatata taaaagaaat tttttaagag gcaatctgct
    36901 atttagttta tttttatctg gtactgcttt attgagttac aatttatatt tatctgttca
    36961 aatcaaaggg ctcatttttt tagctattga ttttatttta ctttttgcct tgctctgcct
    37021 atttgctact tatcaataca gtatgatttt agatagtgaa tatacgatct ctgttcctaa
    37081 tctgctaaag ctaagtttta tttcggtttt ttccagcttt tcgtcttttc taaaaataat
    37141 tattggtagc ggtataattt taggcgtgac ttggcaattc aaaggattga tcctgtttgg
    37201 tgtcattggt cttttgacgg tttggaatgg tacgatgaca acacattggc gtgaagaatt
    37261 agataaacag ttggaaagtt atgaataagt ttcggattct attttcaaaa ggaaccttac
    37321 taaatcgtct gttgcggaaa tacgcggtta tcatgatcgg tgtaacgatg actgctaccg
    37381 ttatttttag tatccatact tgggaacaaa atcaaaaaca ggcagaaaac atgacaagtg
    37441 atgccgttca aagcacaagc agaatgctga atgataaaac aaccttgagt aggatcatca
    37501 aaaaccagct tgtagggaat tccgaaaaga tcgaaaatgt gacgacctac ttaacaaaac
    37561 ccatagatca gtatctgatg tatgtatacg aacagcaaaa cagtaccgat gaattagttt
    37621 ctttcccaaa tcaaatcaaa gatctctacg caaattatga agaactaagt gcgatatata
    37681 tcgtgttgaa tcaactaccg gagtattatg aatcttctag agaaaacaaa ggtggggaaa
    37741 taaaaaaggg gacaccaaaa ttactagacg ccttttatat caagttgcct atcacacaag
    37801 gaggagctga gtcaggaagt atttttattg gttttcaaaa gaaagaacta gatatgattt
    37861 tagaaaatct aacgtcattc aatggactct ctttatacat gatttctgga acgacaaatc
    37921 gactatacac attccatgat aataaaatag ctaaagaaac gtttgaaaga caagaaatga
    37981 tcatcacaga gagtctgaag aaaaattcac aattgccgat tgacgatctg gaaaaaaaca
    38041 attttgttca acaccaagaa ctgtctgatg attatcgtat attagctgta ctagataaaa
    38101 aaagtgtaaa aatcgaaacg ggaaaaaatc ttgccccgct gatcattggt atcattattt
    38161 tagacaatat actgcttatc tttctttata aaacattcaa acgatattca cagcaagtat
    38221 ctatcgtcat gcaggccatg gatcaaacag cagcagggaa tttagagacg cggatcgaca
    38281 taacaaacac ggaatatgaa ctgaaggaac tttcaatcgg tatcaacgaa atgttggata
    38341 gcatcaatca gtttgtagaa gacatctaca aattagaaat caaacagcaa gacgcacata
    38401 tgcgggcgct tcaagcacag atcaatccac actttttata taatacatta gaatatatcc
    38461 gaatgtatgc aatcagcgaa ggaagtgaag aattagcaga tgttgtgtat gcgttttccg
    38521 ctttgcttcg aaacaatacg aatcaagaga aaacgatcac tttaaaagaa gaactggact
    38581 tttgcgaaaa atatgtctat ttgtatcaaa tgcgttatcc taatcgagta gcctatcatt
    38641 ttatgatcga tcctgatttg gaaaagatcg aagtacctaa atttgtgatc cagccattag
    38701 ttgaaaatta ttttaaacac ggtattgatt ttactcgatt cgataatgcg ctaagtgtca
    38761 aagtcttgca ggaaggcaaa cgggtaagga tcatcatcaa agataatgga aaagggatga
    38821 ctgaaaaacg gctaaaacag attgaagaaa aactgtctca tcctaaagtg gaacttcacg
    38881 gttctatcgg tctgcaaaac gtgaatgaac gtttacgtgc cagcttcggc agcagttatt
    38941 atatgtcgct tgagaataat gagacaggtg gactgaccgt ttctattaca ttcaaggagg
    39001 gatgagcgtg tatcaagtgt tattggtaga tgatgaatac atgattttga atgggttaaa
    39061 aaagataatt gattggcaaa gtttaggctt tcaaatagta gcaacagcag agaatgccaa
    39121 agaaggacta gctgtacttg aacagcgaca gattgattta gtagtaacgg atgtgacaat
    39181 gccagaaata aatggactgg aatttattga agcggctcaa aaagaacgtc ataattttga
    39241 atttatgatt ttatcaggat accaagaatt cgattatttg aaaggaggta tgcaattagg
    39301 cgccgtgaat tatttgatga aacccgtgaa taagttcgaa ttggttgaaa gcctcaagaa
    39361 aatcaaaaca cggttagatc agcaaaatga acaaaaaaat caacaagaaa tctatcaaga
    39421 actgttattc agtcaatggt tgaatgaaga attggatgaa ataagtgaag aagaaataat
    39481 aggacaaata agtgagaagc agcataggat agtattgatt caactggcaa gaactcatga
    39541 tactcttatc aatagatggt tgcaagaacg gcaacaaatc ttttactatc aacgaaatta
    39601 cggagaccgt gtattgatca cgttgttgtt ggaggcagat gaagttgatg gcttctgttg
    39661 ttttgttcaa gaaaactttc ctgatcagga atggctgatc agtatcgggg aagagacaga
    39721 ttctttggac aaaatccctg aaacattcca acaagcgaaa gacaatctac agttgcatca
    39781 attttatgga gataaagacg agcatgtttt ttacgcagta caagcagaaa caaaagatca
    39841 aaccatcgat ttttcaagtt tcagacgcgt gctgcaaaat aaacaattgg aagtcgctca
    39901 aaaaatgatc actgattttt ttgaacagtt tcagttagca gccatgatgc cggaagatat
    39961 acgatattcc agttttttac tgtttatgga gattcaacgg gaattgattg atctggaaga
    40021 tgaggaatat ttacaaggaa tcgaaaaaat ccatcaggca aaaacggtgc aagaacttca
    40081 gcagctactt ctgtcattca tcaaaaagca tcagagacag aaaaagtaca gtgacaatgt
    40141 ggaaaaagta atcgtaatcc tgcaccagca ttatcaagaa ccacttacac tcaaagaagt
    40201 gtcagaaaac ctgcatttaa atgtcatgta tctaggacag ctgttcaaaa aagaaacgaa
    40261 aaaaagtttt tcagcttatt tgaaccattt acgtatggaa aaagcgaaac aactgctttt
    40321 gcacagtaat caaaacatca atgagatagc aagtgagatt ggctacaaca acaccacgta
    40381 tttctctaaa ttattcaaga aaatcgtcgg cagatcccct aaagagtacc gagaaaacag
    40441 tggagaatca taaaagaaaa agccaatgta atgaaataac ttataaaaaa ttgtctagaa
    40501 atctaatttt gggctgttct tattacttga ggcaaggcag ctttttcatg acctctcgat
    40561 aaacggagtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtggaaa
    40621 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca cgacctctcc
    40681 actaaacggt gttcaatcag ctgaccctcg gtattagctc aaaaaatggc aaaatatgag
    40741 gaactatttt gccatttgtc tctctaatac tcaggtcaga acgctgattt cacaacctct
    40801 caataaacgg tgttcaaaag cttgcatctg cggtaataag accaaccaaa cgaaaaatat
    40861 gaggatctat ttttgcttgg ctgttcttat tacttgatgc aggacagctt tttcacaacc
    40921 tcttgttaat tatagtttga taaggaaaaa ggcaaatctt ttgcttgata tttcttaggg
    40981 tgagggatga tccctaattg gtaagagatc gtgccgcctt tcagcaaatc ttgatgggta
    41041 aaatataatt tcgtatattc tttgtccatc cgtttgattt tatggataaa ttgttgctgc
    41101 ggccgattag gcgttgcttc aatcgtcaat tcctttccat ttgacaaaag caaaacagcc
    41161 ttgtcaatta atggcatacc gataacatat tcaccggttc caggcgtgac aggataaaat
    41221 cccagactat tgaagatata ccaagcggcc atacttccat tgtcctcatc tccagggtaa
    41281 cccattggag aatcgtcgaa ggtctgagtc atcaactgtt taagcagtgg ctgtgccatt
    41341 tcaggttgtc ctatataact gaacaagtaa ggatagtgaa aacttggctg gtttgaaata
    41401 gctaattgtc caaattctat cgcggccatc tcactcattt cgtggatctc aaaaccatat
    41461 cctcctgggt caaacgttgg gggctgattg cacagctcaa tgagtttttc tttatatctc
    41521 tcactgccac catattttcc gatcagtcct gaaaaatcgt gataaacagc aaagctgctt
    41581 tgccaagcac ttccttctgc ataatcttgt ccccaacgat tagctgaaaa tggttctctg
    41641 aacttgccat ctttatcttt tgaacgcata aatcctgact catagtcaaa gatattttga
    41701 tagttcaatg attgctgctg atatttcttc gtcatttcct cttcttctag taccttggca
    41761 acttggctaa tacaaaaatc gctataagca tagtctaatg tgtgattgac tgattcgtgg
    41821 tagtgattag gaacatagcc atatgtcaag taatcttctg ttccttggcg tccataattt
    41881 ggatgtttgc tttgaaccgt agcacctttt tccattgccg ttagaaattc aggcatcaag
    41941 tctcgtcgga tatcttttac agcagcatct gcaatgaccg catcgatcaa tgtcccaggc
    42001 ataagtccac gttcatcagg agacagccat tttggcaaat agccactttc tctatagctg
    42061 ttcaaaaaac cttccagcat ttcttcgtat ttttctacag caatcaaaga ataaagagga
    42121 taaaccgttt tatacgtatc ccaaaaccca ttatttgtat agagaacacc aggttttata
    42181 gatcgactag tcgtatcata gtggattttt tgcccactag gatcaatttc ataaaatgtt
    42241 tgtggaaata aaaacacccg atataaatta tgataaaacg tccgcaattg ttgttgatca
    42301 tggtgtgtga gctgtatacg atcaaaatag gactgccatt gttcttgact gtgagcaagg
    42361 taagtctctt tgctttggtt ttgttctagt tccaggttat aagctgcttg ttccgagctg
    42421 ataaaagatg tcccaaatcg gatagtttgt ttttttgtct gttcaaaata caacgggatc
    42481 gagtcgctat ttttgttgga aacagctaac tcatcaattg ttaaaggata ttcaaatctc
    42541 aatataaaat aaaaagaaaa atcaggatct tctgaaccag caaaatgtgt gatttttcct
    42601 tccactgtgt aaggatctat aacaaagagc tgatggcgtc ccggaaagga taaaagtaaa
    42661 ccgctgtcat ttttgctgta atcaatagat aagattccgc catacatgct aggtatcaat
    42721 gtagaacaga tgccataacg taattgacag atcgacagat gagtcgggca aaatatactt
    42781 tcttctgggc ggtaagaact ttgagcatgg aaaagggtgt tctcctgtag ttttccattg
    42841 atcggcgtaa acagcatatg actggaatca cccatccaag gacttggttg atgggtaaga
    42901 cggtagcctt gaaaaacgcg gtcatcagga tgaaaccacc agctgccgtt ttgatccgta
    42961 gtttgcggtg caaaataatt catcccaaaa ggaacgccag tataaggctg gcagttccca
    43021 ttagagaaat ttggctgatt cgctgttgca tgtctagtat ctatttgacc gatattcatt
    43081 ttatttctcc tttgttgatt gtcttttgat gaatgaaact ggaaatttac tatcggatgg
    43141 tcgatctttt gtctctaacc aagtgaccaa agcatctccc gcaagcttac ctaactgttc
    43201 aaaatcttgt gcgatggttg tcagtggcgg gtcaacaaga gctgctgctt ggatatcatc
    43261 aaatccgata attgaaaaat cttcagggat atgataacca tgctgtctca agagattcat
    43321 ggtctggata gcgacaacat cgttttcaca aacaaaagca gttacttcat acttagtgat
    43381 ataagaaagc aattcatcta atgtcgcgct tttgtcatcc agtgaagtgt ggaaagtcaa
    43441 accagctttg tccaatgctt caaggtaacc aaggtaacgc tgtcgaacgg attgtggatg
    43501 agtctgcgta ccaaacaaat aagcgatttt tgaatgtccc tgttcgatca aataagaggc
    43561 agcaagcgca ccgccttgga aattatcgga aagaacggta ggaaaaggta actcatagat
    43621 ttttttatct aatatgacga cagggaattc tttcaatgaa agctcaaaaa gtaagtcaag
    43681 atgttgttct gtatcaagag cataataaat caatccgtca aattcattga ttagctcttt
    43741 tgctgtttta ttttgtagaa agtcaagcgt cgtcatcatg acatcaatct gtttatcttg
    43801 catcacaggg ttcaatccct tgctaaaatc accaacagac aaatcagcga catatggaag
    43861 aagaaacaga atccgtcgtg tttttgtagg agaagcaaga atctgttccg gagaagcgga
    43921 tttaacgaaa ctgcctttcc cgcgaacgcg ataaataagt cctaattgct ctaattcagt
    43981 caatgcacgt ttggaagtga ttctgcttac tttataggta cgtgaaagtt ctttttcagt
    44041 tggtagttgg ctgtctacag gtaattcacc agttaaaata gccgtttgca aatcattaaa
    44101 tattgtctgg tacaatggtt gattcatata aacacctctt aatgatatat catattcaaa
    44161 taataccata atggatgaaa aagtaaataa aaagatattt tttgaaagcg tagacataat
    44221 tggctgtatg aagtataatc tttaaagata tatcaaatag aaagaaggtt ttattagtgg
    44281 cttataaaga tataccaaaa tcggtgcaga aatttatgga agatatcaca caaaaatgtg
    44341 gggatatcca tgcggactgg gcaaagaatt ttacagcagc atttgccaat actctgttga
    44401 caacagtcaa aaagcaaaat gacggaacca cctttttatt gacgggagac attccagcga
    44461 tgtggttaag agactctact gcacaagttc gtccttattt agtgattgca aaagaagatg
    44521 aggaattagc tgacatgatc agcgggttag tcaaaaagca atttttttat atcaatatcg
    44581 atccatatgc gaatgccttc aacgaagaag ctaacggtgc tggccaccaa acagatcata
    44641 caaaaatgaa cgattggatc tgggaaagaa aatatgaaat tgattcttta tgctacccaa
    44701 tacagttggc ctatcttctt tacaaaaata caggaaaaac tgatcaattc aatcaatctt
    44761 ttattgaagg tatcaaaaaa atcttggacg tgttcaaaac agagcaagat catgaacact
    44821 ctccttatac atttgtacga gacacgacaa gaaaagaaga tacgctgatc aatgacgggc
    44881 gaggtgcaaa aacagctttt acaggaatga catggtctgg tttccgtcct agcgatgata
    44941 cttgccgtta tggatatctg gtaccatcca atatgtttgc ggtggtcgtg ttaggttatg
    45001 tggaagaaat ttttcaaacg atactcgatg ataaagaaat tgtacagcaa acacagaaat
    45061 tgaagaaaga gatccaagag gggattcaga atcacggacg aacggttaat caaaaagggc
    45121 aaacgattta tgcatatgaa gtagatggaa tgggaaacgc cacagtcatg gatgacagta
    45181 atgtgcccaa tctgatcgcc gcaccttact tgggatattg ttctgaacaa gaggaagatt
    45241 atctgcaaac aagaagaaca ttgttgagta aagaaaatcc atatttctat gaaggaaagt
    45301 acgcaaaagg aattggatcc tcccatacgc cagaaaaata cgtttggccg attgcattag
    45361 ctatggaagg aatgacaacg tcagacaaat ctgaaaaaga gcggatattg aatttacttg
    45421 tagcaactga cgcaggaaca caccttatgc acgaaggatt cgatgtgaac aatcctgaaa
    45481 attatacgag agaatggttt tcttgggcaa atatgatgtt ttgcgaatta gtcatggatt
    45541 actttgatat tagagtagaa aagtaggagg tatcgtaaat gaaaaagaaa gtatatatca
    45601 tttctcatag ccactgggat cgtgaatggt acatggctta cgaacagcat cacatgcgac
    45661 tgattgaatt gatagacgat ctactagagc tatttgaagt tgatccgtcc ttcaacagtt
    45721 ttcatttgga tgggcaaacg attattttag atgactatct tcaagtaagg ccagaaaaaa
    45781 gacaggcaat ccaacaagca atcaatgaag gaaaattgag aattggacca ttttatatct
    45841 tgcaagatga ttttcttatc agctcggaat cgaacgtgag aaatatgctg attggcatgg
    45901 aagaaagccg taaatgggga acccctgtca tgttaggcta ttttcccgat acatttggaa
    45961 atatgggaca gacgcctcaa ttaatgaaac aagctggtat ttcagcagca gcgtttggcc
    46021 gtggtgtaaa accaattggc tttgataatc aagttttgga agcagaaaac tattcttccc
    46081 aatactcaga gatgtggtgg aaaggacctg atcaaacagc aatctttggt ctgctatttg
    46141 ccaattggta tagcaacggg aatgagattc cagtagaaaa agaagcagct cttgcctttt
    46201 ggaagcaaaa attagcggat gcagaacaat atgcctctac gaaccactta ttgatgatga
    46261 atggtgttga tcatcaaccg gtacaaaaag atatatcaaa agcaatccat ctcgcaaatg
    46321 aactgtttcc agattacgag tttattcatt ctaattttac tgactatctg gaagcagttc
    46381 aaaaagatgt gccagaagac ttaggctcag tagaaggaga attgacaagt caagaaacgg
    46441 atggctggta tactttagcc aatacagcat ctgctcgggt ttacttaaaa caatggaata
    46501 ccaaggtcca gcgacagcta gaaaatatta cagaaccact tgcgacgatg gcttatgaag
    46561 ttagtggaaa ctatccccat gatcaattag attatgcttg gaagacatta atgcaaaatc
    46621 atcctcacga cagtatttgc ggttgttcag tcgattctgt ccatcgggaa atgatacctc
    46681 gttttgaaaa agcagatgaa gttggaaagt atcttgcaca agattcctta gaacagctga
    46741 ccgcagcaat cgatacgacc ggattcccaa aagacagctt tccatttgtc attgtaaata
    46801 ctgcaggaat ggataaaact ggtgaagcag aaataaccat cgaattagaa agaaaaagat
    46861 tcgctgaagg aatacctgaa caactatatc aagagttaga aaatttgcct aaacgtaagt
    46921 atcatgtaga aacaaaaagt ggggccacta taccagctat tttatctgaa gaaactgtcc
    46981 aatttggtta tgatttgccg aaagaccgtt tccgtgtgcc atatatggca agaatgatca
    47041 aagtgacttt accattagaa aacatgccag cattttcttg ggaaacattc gcgcttgtag
    47101 aaggggaagc gaaagcagaa gaaaaggaaa caatgattca tcagagtgga cgaatcatcg
    47161 aaaacggccc tctacatttg acgattgaaa aaaatggtac cattacaatg gaagatcgca
    47221 aaaacaaacg aaagttgaat aatctgcata tttttgaaga tatcggcgat ataggaaatg
    47281 agtatatctt taaacaacct ttctgtgatc agccaatcct atccagtaac aaagaaaact
    47341 ctgaagtaaa agtattagta gatacaccgg aaatagcaaa aataagtatt ctacaggaaa
    47401 tggaaatccc tgtttctgca gacgagcgtt tagaaaaaga acagcagatg gttgtggaat
    47461 ttcgttatcg aaaagcagaa cgatccaaag aaaaacgaat ccttcaaata aaaacaatca
    47521 tgacaatcag aaaagatagt aaaaaaatcg actttgaaac gactctcgac aatcagatga
    47581 aagatcatcg cttacgtgtc ttgtttccta caaagttaca tgtggaacat cacgaagcag
    47641 atagtatttt tgaagtggtg aagcgcccaa accatgtgtc taaaagttgg gaaaacccca
    47701 cgaatccgca acatcagcaa gcatttgtca atattcatga tgaagagtac ggtgtaacag
    47761 tcggaaactt tggtttgaat gaatatgaag taacagaaga cggacaaatc gcagtgacgc
    47821 tacttcgcag tgtgggagaa ctaggcgatt ggggatattt tccaacacca gaagcacagt
    47881 gtctaggtga gcatcggttc aattacagca ttgaactaca tggaccagaa gaaaaattct
    47941 ctacttattt gcatgcatac gcagcacaga ttcctttttc cactcaacaa atcaaacatc
    48001 atgaaggaac attgatttca aaacaacaat atttaacgat aaaaagtgaa acgtttgcaa
    48061 ttacagcttt gaaacgcagc aagtttagtg ataaagtagt agtaagaggt ttcaatatgt
    48121 ctagtcattt agaaaaattg gaaataacta aagacaatgg aaaaactgtc atattgaatc
    48181 tgcttgaaga accaacgaag caagcggttg tcccaataat ccaaccttat gagattcgga
    48241 caatcggatt cgaggaggaa aacgaatgta tggcggaata gaagcaggcg gaacaaaatt
    48301 tgtgtgtgcg gtttcagatg gtggagaaat tttagaaaaa ttaagtatcc ctaccacaac
    48361 accagaagaa acattggatc aggtatttga attttttgat cgttatgaat tgaagggaat
    48421 cgggattggc tcattcggcc cgattggtat cgacaaaaca aaagataatt acggatacgt
    48481 tttggcaact cccaaaaaag ggtgggcaca attcgatttt cttggcacaa tcaaggaacg
    48541 ctacaatatt cctgctgctt ggacaacgga tgtcaatgct gctgcatatg gggaattgaa
    48601 gcaaggagca gcacaaggaa aaaatagttg tatttacctt accgtgggaa caggaatcgg
    48661 tgcaggtgtc gtgatcaatg aagaaatttt ttcagggatc gcacatcctg aaatgggaca
    48721 tatttgggtg aaacgccatc cagatgacca ttatgaaggt acttgtcctt atcataaaga
    48781 ttgtttagaa ggattagcag caggaccgtc tattgaggca cgcacaggga tcaaagggca
    48841 agatctgccg caagatcatc ctgtttgggc tattcaggct tattatattg ctcaagcact
    48901 gatcaactat acgttgacgt tagcacctga aaagattatt ttaggcggtg gggtaatgaa
    48961 tcaggatcat ctccttcaaa aaatccgtca gcaatttgtt gaattgatgg gtggttatat
    49021 ggaaacacct caagtaagtg aatatatcgt tcgttgggga ctgccgaatg aaagtgggat
    49081 tatcggtagt ttgctgttag cagaacacga acatcaaaag taagcagaca aattacacaa
    49141 aaagaacaga gtcttatcat tatctgctga taagactctg ttctttttta tttctattcc
    49201 cataatccag gtaaagcttt accgactatt ttttcttgag taaatggatg gatcatgtgc
    49261 agttctaatg catggagcat cagtcgttca gctgttctat tttggtagag agggtctcca
    49321 acgatcggat gtcccttatg agctaaatga actctgatct ggtgtgtacg tccggtttcc
    49381 aaaacacaat agacttgtgt ttgttcagaa agtactttgt tgacagtgac atgtgtcaag
    49441 gcgctctgac catttttatc atctacgacc ctttttctcc gatcatggcg atctcgtcca
    49501 attttattgg tgatggtcat atctttggca atttctcccc atacgatggc ttgatatctc
    49561 cgatagatca ttttttgttc caacattctt ccaagtatcg gcaagacaaa tggatttttt
    49621 gcaaataaaa cggcaccgct tgtttctttg tccaagcggt ggacaacgta aggtcgttgc
    49681 tgtttagtgt cgagataagc agctaaatga ttgagtaagg tactgttttc tgtcggttca
    49741 tttggatgag tcttcattcc tgcaggctta tccactataa tcaaatgctc atcttcatat
    49801 aaaacacgga tgtgcttcgc atctcctaat tgaacttctt gataattata atctgtttct
    49861 tcgaataaca atgtgatctg gtcattgccc tttacttcat gatggaacaa agcaggttgt
    49921 tgattgatcc aaacgttttt acgtatacgc aaaaagtgtc gaacctttct aggaactaac
    49981 cattcctttt caagcaagtc gcgaattgtt gtttcaggat ggttcatagg taaagtgatc
    50041 gtgattttca caagtgtact cctttcagtg caatcgcaga ctaattgtac catttttaaa
    50101 acatatttaa gaaaaaactt acatttttct gttcattctt atgttactct acttgcacta
    50161 acgtaaaaaa acatattgaa ctacaactta agcaggaaga aaacactctt tcactatggt
    50221 aaaataagac gattgaatca aatagacagg agaagaagca aatggatttt caaagcattt
    50281 tagaaaagat aaaagctgct ttgatcagtt tttggcgttg gatcagacca tatctcggac
    50341 aattccatcg atggcgaaag cgcatctgga aaaaatatca tgtgaacaaa ttgattttgc
    50401 tgattggttt gatctgtgtc ttagtgacaa gtatctacct ctttatttta gcaaaacaag
    50461 caaatgtcga aacgttaaaa tcaggattaa gccaatcgac agtcatttat gataagaaaa
    50521 acgaagaagc tggcacactg tacgcccaaa aaggaacata tgtagaatta aacgcgattt
    50581 ctccctatat ccaagatgca gtaatctcga cagaagatag gaatttttac gagcatcacg
    50641 ggtttgatat caaagggatt gcccgtgcag cagtccgaat ggtcttgtct ggcggaacat
    50701 cagggggcgg aggaagtacg atcactcagc agcttgccaa aaatgcgtat ctgacattag
    50761 accaaacgtt tgatcgaaaa gcgaaggaat tatttttggc aatcgagatc gaaaagaagt
    50821 acagcaaaga agaaatcttg accatgtatc ttaacaatgc ctattttggc aacggggtat
    50881 ggggtgtcca agacgcttcc agaaagtatt ttggagtaga tgcaacgaat gttacgctgt
    50941 ctgaggctgc tactttggca ggaatgctga aaggtcctgg tatttataat ccgatcgatc
    51001 acccaaaaaa tgcgaatgat cggaaaaaca cagtactaag tgtaatggaa gaaaacggaa
    51061 aaatcacaaa agaacaagaa caagcagaaa gccagacaga tatcagcgcg tatcttaatg
    51121 acacatacga taattcagat tctggttatc gttatcctta ttattttgat gcagtgatcg
    51181 atgaagcagt taacgagtat ggtcttgatg aagaagatgt catgaataaa ggctataaaa
    51241 tctatacagc tttagatcag gattatcaaa agcaattaga agctacttat caaaacagtg
    51301 cattattccc agcaaatgct tcagatggtg ccatggtcca atctgcttca gtagctttag
    51361 atccgaatac aggtggtgta caagcactag taggacgaag aggagatcat gtctttagag
    51421 gattcagctt tgctacacag atgcgtcgtt caccaggatc aacgatcaaa ccattaagcg
    51481 tatatacacc agcactggaa gctggataca agccttccag tatcttgaaa gacgaaccgc
    51541 aaagttatta cgatgcgcat aattttgacg ggacatacca aggagaagta ccgatgtatc
    51601 aagctgttgc acaaagtttg aatttgccta ctgtatggct tttgcatgag atcggtttac
    51661 aaaaaggata tgataaagca gaagaattcg gcctgccttt agcaaaatct gataagtatt
    51721 atggcttagc ccttggtgga ctggaaaaag gagtatctcc attgatcatg gcgggtgctt
    51781 acagtgcatt tgccaatgat ggtcagatgt atacgccgca tcttatcacg aaaatcgttg
    51841 attcgactgg agcggtgatc gtcgataaca caaacaaaaa accaaaacag gtcatatcaa
    51901 aggaaacagc cgatgaaatg accagcatgc ttcttggtac attttcaaat ggaacagcgg
    51961 ctgctgcgaa tcctgcaggt tatacgatag cagggaaaac aggaaccaca gaaactaatt
    52021 tcgatgccac aaaagcaaat gaccaatgga tgatcggtta cacgccagac gtagtgattt
    52081 cgacatggat gggttacgaa gaatccagca agctgcacta tttggaaggg acaagtggaa
    52141 atgttgtcgg gaaagtcttc aaatcagcgg cagaaggcat ccttccgtat acttcaaaaa
    52201 caggatttag tgtagcagat gcctatgcca caggaggaca agtggtagct gcagatcaag
    52261 ttggaaacac aggaaattct aatggagagt ctggaaattg gcaagataac ttgaatcaat
    52321 atggtgaaca agcaaaagaa gggctgaaaa acttcggcga tatggtgaaa gaaggcgttc
    52381 agggaattgg tgaagcggct aaagacctct ggcggaaata tcaaggagag tagccccttt
    52441 gaaaacgaat aaccccatgt tacaatagag agtaactact aaaagaaaag agggcataac
    52501 atgtcaaaca tctacgatag cgcgaatcaa atcgaacgtg agatccgtga attaccagaa
    52561 ttcaaagcgt tgaaagaagc gtacgagaaa gtacaagcaa acgaagaagc acacaaactg
    52621 ttcaaagact tccaagcgat gcaaatcgaa ttacaagaaa aacaaatgag tggacaagag
    52681 ttcagcgacg aagatgcaat gaaagcacaa gaaatggctg tgaaaatcca atcagaagaa
    52741 gtaatcaatg acttgatgca aaaagagcaa ggcttcagta caatcatcaa tgacttgaac
    52801 cgtatcatca tgacaccagt tcgcgacctt tacagcgaat aaaactattt tatgaaacaa
    52861 cagagggtgt gaaagagacg ttcggccttg agcgatgaca aaattgcttc ttattgccga
    52921 taggctgtct cttgaacacc atttaccaag aggtcgtgag cctaccgttt aactctgagt
    52981 tacaaggaac aatttcaaaa aacagcttct catgtttgat gactattgtg acttgtgacc
    53041 gaggagttgg caggagaaca ccgtttattc agaaatagga gctacgacaa aagtcttgtc
    53101 atagctccta ttttttgtca ttcatttttc aagcggtaga aatagccttt ttgagctaac
    53161 agtttttcgt aagtacctat ttcaacgatt tttccttcat cgatcacaac gattttatct
    53221 gcctctttga tcgttgaaag ccgatgagcc acaataaaag tagtgggtgt ttctgtcagg
    53281 taattcaggg cttgctggat ttttttctct gactggttat ctaaagctga ggttgcttca
    53341 tctagcaaaa tgatttttgg ctgacgtatc aacgctcgtg caatggagat acgttgcttt
    53401 tggccaccag acagcttgtt gccatgttcg cctactaagg tatccagacc atcaggaagc
    53461 tggtcaatca gtgaagaaag ttgcgcagct tcgatgactt catctaaacg ttcttttgat
    53521 acgtttttca agccataagt gatgttctct ttgatcgaag cggagaacaa caaagtggtt
    53581 tgaggaacaa cggctaaata atttcgcaca cttcgcatat ccagttcatc caaaggctga
    53641 tcatctagaa aaatttttcc tgaagtcggc tggataaatc caatcaataa gttaaggagt
    53701 gtagattttc cagagccaga tggcccaaca aaagcaattg tttctccagc tttcacctct
    53761 agagaaaaat gatcgataat cggtttgagt gagtccggat aaagaaaaga aacatcctca
    53821 aaacgaaaat ttccatccaa atgttggatt tttttcttac cgtgataagt ttctacatcg
    53881 ccagcaatca acagttcgcc aatagaagtg atagattcca tgccttttga aatcgtagga
    53941 atcagcgtga tcattccaga aacggaattg acgatcgtcg tgaaatacgt ctgatacatc
    54001 acgacatcgc cgggttggat gcgcccttgt aaagctaata tcccagtgaa aatcaaacaa
    54061 atcagctgaa atatctgaaa actagcccag ctgactgatc cgaaaacaga ttgcaggata
    54121 tctaagtgga atcctttttc atagatttga gtaaaatgct tatttaagcg agttgtttcg
    54181 tgtttttcta acccatgagc tcgagcaatc ggtgctaatt cgatcacttc gatcactttt
    54241 gcagaagtct cttccatttc ttgcctgaag tctgagttgg actgtctgat ccttttacgg
    54301 aaaaagagag taacgaatgc ggcgagagga acagtcaata agaaaaacat gaaaacaaca
    54361 ggacttttat aaagcgtgat acctaaagct acgaataaat tgacagcgat atttaatccg
    54421 ctgacaaata cttgagagga caacgtttgg atagcttcta catcacggat gatctttgac
    54481 tggattcgtc cagattgcaa ttctttttga taaggaatag atagttcttg gattttcttg
    54541 ataagggtcg ctcttagtcc agcttctact tgacggatcg aagtgctatg gtattttaca
    54601 tgaaaataat tcgtcaatat attttgacca atcagacaag ccatcaaaaa agcgttgaaa
    54661 taaatggcct gcaactgaga agaatctttc gatgaagctg cattgattac attggcaata
    54721 gcgatcggca ttaaccaaga tggaagatgt ttgataataa aaaagagtcc tgacatggca
    54781 aaacgccaat aatttccctg ataaagatgc agcaatgtct gaaaagcatt tgcatgatat
    54841 ttttgataac ttttctgtat tcgttcctcc ataatcttct ccttaacaat cttggtaaat
    54901 aaactgcaag tgttctattg cttcaggaac ataaatctca ggagtagctt caagagtggc
    54961 gtacattaga ggacgctcat atttgatata atgcagtacc gggcggaaat ctaaacagcc
    55021 cttgccaaca ggtaccatgc ggatctttcc attttccatg atatagtctt tgagatgaag
    55081 cgctgtaata taaccatgta aattgtccaa ggcacctcgg atcacttttt cctgatcagc
    55141 atgattttct ttatgcatca aattcgcaca atctaaaatg atttttaaat ttggtgaagc
    55201 tacttcatcg attaaacgtt tagctaactg atagttatag attggatgat tgatccctgc
    55261 ttcaacagca acagttacgc caaaattttc tgcatgagcg actaattcaa tgatagaatt
    55321 tctggcgatc tgataagctt cttcagtaaa attttctttt gtgtaaccga cagagacact
    55381 accggtttcc gtagcaatca tcttggcttg ataggcagag cacagagcaa tttgctgttt
    55441 gaaagttgcc aatgcttgtg cacgaacttc ttgatttttg ctggataggt tgatatagca
    55501 tcctaaaatg gaaagttcga tattgttttt ttggaagtat tcaccaaaat aggcagcact
    55561 cccaagtgtc atgtcagtta atttaagttg ttcaggaaat gctttttgtg gtgcaaattg
    55621 gatatgggac aagtgaagct gtgatacttt ttgaacgatt tcttcacgat ttcgaacatc
    55681 taaatcgtgg gcacggatgc ctaaatttaa tggaaacatc tcaaactcct ttttgtaaat
    55741 aattagcaag aggcagacgg gattctttta tcaattcaac aattattcgg gcaactttat
    55801 cagcgccttc tggactaaag tgggtattgt cttttagtcc ttctgggtaa tttttacaag
    55861 tatcaggtat aagatgcagg tagaattttt ttgtctcttc ttttgagaag gtctggaaca
    55921 attcttgtga tcttgagaac acatctaaaa gaggaatatg gtgtttctca gcaaatgcac
    55981 gcatcgcttt tggatagtct ccaagtatat ctggattcaa tgttccgttt tctaagtaat
    56041 ctcgtcgcgt cacagatgtc agtaagacca tttggacgtt cgcttttttt gcgcattcaa
    56101 aaaatatctg cagatttttt aaatagctac cgaagggaag cgtacctctt tcttcttgga
    56161 ttttctggtc gttatgtcca aattgtacaa ataagaaatc attcggctga aactgtgaag
    56221 ctagacgggc taaccttcct tcctggataa atgatttggt gctgcgtcca ttctttgctt
    56281 ggttattgat ctggatctcg ggtgaaaaat aagcagagat tttttctccc caacctgtct
    56341 cgggacgctt gttttcatct ttttctgccg cagtagaatc accggcaata tggatagtag
    56401 gcatgttatc tcttctttca taaaggttta taggcaatga agcagaacag caagagaaga
    56461 agacggagca aatttggtcc gtcttcttct ctaaaacgtg gataaacgga ttccgttatt
    56521 tcactatcct gtttttgatt cgttactgtt actattaatc aattaggcaa aaaagccaaa
    56581 gtaattttta gcatttgtat aactaatcgc ttgaactaga cttcctaaaa gttgttcatc
    56641 ttcaggtgct tctcctcgca tgaccatttc gcctaaaaat tcacaaagaa cacgacggaa
    56701 atattcatgt ctagtgtagg acaggaaact tcttgaatct gtcagcatgc cgacaaaatt
    56761 ccccaaagca ctaccatcag caaattgtgt caattgatcg cgcataccag ctcgagtatc
    56821 gttgtaccac catccagaac ctaactgcag ttttccattc tgttcttttt ggaaacagcc
    56881 catcaaagct aaaatcgcag gatagtcatt cggattcaat gaataaagga tcgtctttgg
    56941 caactgatcc gtttcttctg cacggttcaa taatttttgc agaggaatag tcaaagaaag
    57001 atcattcatt ccatcatagc cggtatcggg ccctaatttt tccaacattt gtgtattaca
    57061 gttacgataa gcatggatgt gcagctgcat cgtccaatta tgagaatgat agaagtgggt
    57121 caaatgtatc agtgtttctg tacgataagc atcgatttca tctgaagata atagtttgtt
    57181 agctcgtgct ttttgaaaaa tctcttctaa tactgtttca tccgcttctt tatagcgtaa
    57241 gatgtctaaa gcgtggtcgg aaacacgaca tccatgttga tggaagtatt ctatccgctg
    57301 ccctaagact tctatcagtt cttgataggt ggtgatcgtt tggtcagctg cttcttccag
    57361 tagtgtgacc catgcattaa atccttcttt ttcaatattg agtgctttat ctggacggaa
    57421 tgaaggtaga accttcaaat ctggttcttc atgagcaagc aactgatgat agtgcaagtc
    57481 gtctgcggga tcatctgttg tacaaatcac ttctacattc gatttttttg cgatttcccg
    57541 acggcgaaaa tcaggagctg ccaaaatttc atttgcttgt gtccaaattt tctctgcatt
    57601 ttcttcattt atcaacaagt caataccgaa gaaacgcttc aattcaagat gtgaccaact
    57661 gtaaagcgga tttccgataa tttttggtac ggtttgacac caagctaaaa atttttcaaa
    57721 atcagaagca tttcctgtga ttttttcttc aggcacgccg caagctcgca tcaagcgcca
    57781 tttgtaatga tcgcctccta accaagcttc tgtcagattg ctgaaattgt tgttttcgta
    57841 aatttctttt ggatctaagt gacagtgata atcaataatg ggcatgtttt ttgcgtagga
    57901 atggtaaagc tttttcgccc aatcgtcttt taataaaaaa tcatcagata aaaacataaa
    57961 tcttccttct ttctttttat actgttttat gaaaatcaaa gtgttactcc gtttttaaaa
    58021 atggcaattt ctcgaacgtc attttgttca tttttcgttt cttctccact agctacagcg
    58081 atgatttttt gaacaaacga ttctaagatt acttccattg gttgttctaa taagacgcct
    58141 gcattaaaat ccatccaatg acctttgcgt tcaaaaagag ttgtattcgt agataccttg
    58201 accgttggga catatgagcc aaacggagtc cctcttcctg tggtaaacaa gaccaactgg
    58261 caatcggatg aagcaagagc agaggcagct acaagatcat tcccgggagc ttgcaataaa
    58321 ctaagccctg gttttctgat tttttcgcca tattgtagca catcaacgac aggagagctt
    58381 cctgattttt gcgtgcagcc taaagactta tcttctaatg tagtgatccc acctgcttta
    58441 ttaccaggag atgggttttc gtaaactggt tccccgtaag acaagaaata ctgtttgaag
    58501 tcattgatca agtcaacgat tgagtcaaaa acttcttcat tttccgctcg tgccatcaat
    58561 acttgttctg cgccaaacat ttctggcact tctgttaaga tcgtgctgcc tccttgagca
    58621 atcaagtagt cagaaaatgc accaagtaaa ggattagcag ttattcccga tagaccatca
    58681 gaaccgccgc atttcaaacc gacattcaac ttagagagcg ggactgatat gcgctggtca
    58741 ttttccgccg ctgttaaaag ctcttctaat agagccacac cttgttcgat ctcatcgtaa
    58801 acatcttgag ccactagaaa tttcactcgt tcttcatcat attcacctaa aatttttttg
    58861 aattcaggaa ctgtattgtt ctcacaacct aatccaaata ctaaaactcc tccggcattg
    58921 ggatgattta ctgcgtccgc taaaatttct cgagtatttt gatgatcttt tccaagctgc
    58981 gaacagccat aaggatgctt taaaatcgta atatggtcaa actgtcccag atctggatgt
    59041 ttttccttga actgtttgac gatcagttca gcaatgccat tcacacaccc aacggtaggt
    59101 actaaaaaca aatcattacg aatccctact tttccatttt ttcgcaagta accttgaaat
    59161 gttcggttct caaaaaggta atgacttgga tggacatctt tttcatatcg ataatccaat
    59221 tcaccagaaa gattggtttt tacattatga gtgtgcagcc attgaccggc agttacgtct
    59281 gtcgtcacat gaccgattgg atagccatat ttgatcacgt tgtctccagc tttcaaatca
    59341 cccaatgcaa tcttatgacc ttgcgggata tcttcaagag tggtgatcgt ttgctgatca
    59401 atcgtcagtt gtgtttgttt tggaataggg gttaatgcga cgaccacact gtctcgtcga
    59461 tttaatttca ttgttggttg cagggtttca agcatggacc atcgttcctt tcatttcttg
    59521 taatactgac cggacacctt tttgatcgat ctttgcagct atttcttgaa ctgtatctgt
    59581 cacattcggt atttgagaca aatcttctcc ccaaagcgca gcgttttgca ataatcgagg
    59641 aatagctgtt ccattatcag accaagcatc agtaaattcg cttatcgtct tttcatcatc
    59701 atgtggcttt acttgatcgc ctcgatacat aagaagtagc gcagctagtg aaacagtgat
    59761 taacggtggt acctgatttt gttcttcgat atacttcttg aacactggaa gcagacgggt
    59821 gctgaacttt gaaacactat ttaatgaaat cgcttctaat ttgtgatggg caaaaggatt
    59881 caagaaacgt tctttgattt ggtcagcata aatggctaat tcatctttag gtaaagaaag
    59941 cataggaatc aattctagat tgaataactg atcaacatat gcggagaata aaggatcttt
    60001 cattacttct tctacagttt ccaattccgc caacaaagca agagggacca tcgctgtatg
    60061 cggtccatta agcaaatgca ccttacgttc acgataagga gtcatatcat ctgtgatgat
    60121 gacattcaag ccagcctgtt tgaatggtag ttgattctcc aattctttag gcccttcgat
    60181 cacccaaagc atgaatggtt ctgctttgac catcaattga tcttcatagt tatgccgttg
    60241 attgaaaaca cctgcatctt cgcgaggata acctgggacg atgcgatcaa ctaaactaca
    60301 acagaaaaca ttttcttttt ctaaccactc aacaaaagca ggttctaaat cccatttttc
    60361 tgcgtagcgt aaaatgattt cttttagacg ttcgccgttt ctgtcaatca gttcgcaagg
    60421 aatgatggta aagccagctt
//
LOCUS       DAYYEF010000011        57517 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000011 DAYYEF010000000
VERSION     DAYYEF010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 57517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57517
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.011"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(61..2424)
                     /locus_tag="ACHA1B_000815"
     CDS             complement(61..2424)
                     /locus_tag="ACHA1B_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase"
                     /protein_id="HFM8701599.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2589..3093
                     /locus_tag="ACHA1B_000816"
                     /pseudo
     CDS             2589..3093
                     /locus_tag="ACHA1B_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035543.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="ACHA1B_000817"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="ACHA1B_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HFM8701600.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="ACHA1B_000818"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="ACHA1B_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HFM8701601.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="ACHA1B_000819"
     CDS             complement(5894..6205)
                     /locus_tag="ACHA1B_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HFM8701602.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="ACHA1B_000820"
     CDS             complement(6202..6495)
                     /locus_tag="ACHA1B_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HFM8701603.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="ACHA1B_000821"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="ACHA1B_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusA"
                     /protein_id="HFM8701604.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="ACHA1B_000822"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="ACHA1B_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0042274 - ribosomal small subunit
                     biogenesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HFM8701605.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="ACHA1B_000823"
     CDS             complement(8333..12685)
                     /locus_tag="ACHA1B_000823"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HFM8701606.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="ACHA1B_000824"
     CDS             complement(12897..14606)
                     /locus_tag="ACHA1B_000824"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004827 - proline-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA];
                     GO_process: GO:0006433 - prolyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HFM8701607.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="ACHA1B_000825"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="ACHA1B_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HFM8701608.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="ACHA1B_000826"
     CDS             complement(16103..16903)
                     /locus_tag="ACHA1B_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HFM8701609.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="ACHA1B_000827"
     CDS             complement(16900..17712)
                     /locus_tag="ACHA1B_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HFM8701610.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="ACHA1B_000828"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="ACHA1B_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008135 - translation factor activity, RNA
                     binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HFM8701611.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /gene="pyrH"
                     /locus_tag="ACHA1B_000829"
     CDS             complement(18467..19189)
                     /gene="pyrH"
                     /locus_tag="ACHA1B_000829"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0033862 - UMP kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HFM8701612.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /gene="tsf"
                     /locus_tag="ACHA1B_000830"
     CDS             complement(19325..20206)
                     /gene="tsf"
                     /locus_tag="ACHA1B_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003746 - translation elongation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor Ts"
                     /protein_id="HFM8701613.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="ACHA1B_000831"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="ACHA1B_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HFM8701614.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="ACHA1B_000832"
     CDS             21446..21925
                     /locus_tag="ACHA1B_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HFM8701615.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="ACHA1B_000833"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="ACHA1B_000833"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047304 - 2-aminoethylphosphonate-pyruvate
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HFM8701616.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /gene="phnX"
                     /locus_tag="ACHA1B_000834"
     CDS             23226..24011
                     /gene="phnX"
                     /locus_tag="ACHA1B_000834"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050194 - phosphonoacetaldehyde hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HFM8701617.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /gene="argS"
                     /locus_tag="ACHA1B_000835"
     CDS             complement(24357..26048)
                     /gene="argS"
                     /locus_tag="ACHA1B_000835"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HFM8701618.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="ACHA1B_000836"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="ACHA1B_000836"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008804 - carbamate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HFM8701619.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="ACHA1B_000837"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="ACHA1B_000837"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004585 - ornithine carbamoyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0042450 - arginine biosynthetic process via
                     ornithine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HFM8701620.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="ACHA1B_000838"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="ACHA1B_000838"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016990 - arginine deiminase activity
                     [Evidence IEA];
                     GO_process: GO:0019546 - arginine deiminase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HFM8701621.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            30332..31033
                     /locus_tag="ACHA1B_000839"
     CDS             30332..31033
                     /locus_tag="ACHA1B_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFM8701622.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="ACHA1B_000840"
     CDS             complement(31605..32621)
                     /gene="tsaD"
                     /locus_tag="ACHA1B_000840"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HFM8701623.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="ACHA1B_000841"
     CDS             complement(32618..33082)
                     /gene="rimI"
                     /locus_tag="ACHA1B_000841"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFM8701624.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="ACHA1B_000842"
     CDS             complement(33089..33631)
                     /gene="rimI"
                     /locus_tag="ACHA1B_000842"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008999 -
                     peptide-alanine-alpha-N-acetyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HFM8701625.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="ACHA1B_000843"
     CDS             complement(33615..34337)
                     /gene="tsaB"
                     /locus_tag="ACHA1B_000843"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HFM8701626.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDKIIVPMFDARRKNVYAGAYRWKENRLEIVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFYEIKEILPSAMINTVPAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(34528..35508)
                     /locus_tag="ACHA1B_000844"
     CDS             complement(34528..35508)
                     /locus_tag="ACHA1B_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8701627.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(35532..37016)
                     /gene="galT"
                     /locus_tag="ACHA1B_000845"
     CDS             complement(35532..37016)
                     /gene="galT"
                     /locus_tag="ACHA1B_000845"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0017103 - UTP:galactose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019388 - galactose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HFM8701628.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(37028..38017)
                     /gene="galE"
                     /locus_tag="ACHA1B_000846"
     CDS             complement(37028..38017)
                     /gene="galE"
                     /locus_tag="ACHA1B_000846"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA];
                     GO_process: GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HFM8701629.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            38266..38433
                     /locus_tag="ACHA1B_000847"
     CDS             38266..38433
                     /locus_tag="ACHA1B_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HFM8701630.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(38495..40306)
                     /locus_tag="ACHA1B_000848"
     CDS             complement(38495..40306)
                     /locus_tag="ACHA1B_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HFM8701631.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(40303..40668)
                     /locus_tag="ACHA1B_000849"
     CDS             complement(40303..40668)
                     /locus_tag="ACHA1B_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HFM8701632.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(40831..41226)
                     /locus_tag="ACHA1B_000850"
     CDS             complement(40831..41226)
                     /locus_tag="ACHA1B_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFM8701633.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(41244..42206)
                     /locus_tag="ACHA1B_000851"
     CDS             complement(41244..42206)
                     /locus_tag="ACHA1B_000851"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004340 - glucokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA];
                     GO_process: GO:0051156 - glucose 6-phosphate metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HFM8701634.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(42206..42418)
                     /locus_tag="ACHA1B_000852"
     CDS             complement(42206..42418)
                     /locus_tag="ACHA1B_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HFM8701635.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(42439..43137)
                     /locus_tag="ACHA1B_000853"
     CDS             complement(42439..43137)
                     /locus_tag="ACHA1B_000853"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HFM8701636.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(43157..43699)
                     /locus_tag="ACHA1B_000854"
     CDS             complement(43157..43699)
                     /locus_tag="ACHA1B_000854"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030272 - 5-formyltetrahydrofolate
                     cyclo-ligase activity [Evidence IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HFM8701637.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(43831..44835)
                     /locus_tag="ACHA1B_000855"
     CDS             complement(43831..44835)
                     /locus_tag="ACHA1B_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFM8701638.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(44832..45821)
                     /locus_tag="ACHA1B_000856"
     CDS             complement(44832..45821)
                     /locus_tag="ACHA1B_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FecCD family ABC transporter permease"
                     /protein_id="HFM8701639.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(45818..46624)
                     /locus_tag="ACHA1B_000857"
     CDS             complement(45818..46624)
                     /locus_tag="ACHA1B_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701640.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            46790..47746
                     /locus_tag="ACHA1B_000858"
     CDS             46790..47746
                     /locus_tag="ACHA1B_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8701641.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(47823..48341)
                     /locus_tag="ACHA1B_000859"
     CDS             complement(47823..48341)
                     /locus_tag="ACHA1B_000859"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA];
                     GO_function: GO:0005542 - folic acid binding [Evidence
                     IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HFM8701642.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(48429..48578)
                     /gene="rpmG"
                     /locus_tag="ACHA1B_000860"
     CDS             complement(48429..48578)
                     /gene="rpmG"
                     /locus_tag="ACHA1B_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFM8701643.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            48806..49252
                     /locus_tag="ACHA1B_000861"
     CDS             48806..49252
                     /locus_tag="ACHA1B_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HFM8701644.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(49447..51342)
                     /gene="asnB"
                     /locus_tag="ACHA1B_000862"
     CDS             complement(49447..51342)
                     /gene="asnB"
                     /locus_tag="ACHA1B_000862"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HFM8701645.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(51667..52641)
                     /gene="bsh"
                     /locus_tag="ACHA1B_000863"
     CDS             complement(51667..52641)
                     /gene="bsh"
                     /locus_tag="ACHA1B_000863"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFM8701646.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(52977..53064)
                     /locus_tag="ACHA1B_000864"
     tRNA            complement(52977..53064)
                     /locus_tag="ACHA1B_000864"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(53030..53032),aa:Ser,seq:cga)
     gene            complement(53209..53775)
                     /locus_tag="ACHA1B_000865"
     CDS             complement(53209..53775)
                     /locus_tag="ACHA1B_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8701647.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            54030..55361
                     /locus_tag="ACHA1B_000866"
     CDS             54030..55361
                     /locus_tag="ACHA1B_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HFM8701648.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            55327..55677
                     /locus_tag="ACHA1B_000867"
     CDS             55327..55677
                     /locus_tag="ACHA1B_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701649.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(55769..56188)
                     /locus_tag="ACHA1B_000868"
     CDS             complement(55769..56188)
                     /locus_tag="ACHA1B_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HFM8701650.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(56189..56533)
                     /locus_tag="ACHA1B_000869"
     CDS             complement(56189..56533)
                     /locus_tag="ACHA1B_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HFM8701651.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            56883..57479
                     /locus_tag="ACHA1B_000870"
     CDS             56883..57479
                     /locus_tag="ACHA1B_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFM8701652.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT        16181 a        12116 c        10052 g        19168 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagc actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcat tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagattgcat taccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattcca tcaaacatac gacctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agaccgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacggcctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg tttggaattt tgattgctaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcgta
    29461 tagactgcta gaacgtactt caatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 ctttgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc ttttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcgtaa tttattcatt ttttattctg tatacacttt caaaaaaata
    30061 tttattcatt gaaaaaaatt ttttgaataa attaaaaaaa taaattatat tagcgttgtt
    30121 agcgtttact atatgtatta ttgttgtttt ttatacacaa atcattcgct tcaaaacaaa
    30181 ttattcaata ccattgtata ttttttacat aataacaaat tatatttgta aagtattaaa
    30241 acttgtttct aatgttggta tgttaaaact ttacaaattc tttaaaaaaa gtgacaataa
    30301 atatagtgaa caataaggag aggacttttt aatgcgtgtt aataaaatcg attttcactt
    30361 ttcaaaactc agatatcaac ctgattttga acatttctcg gatgaagagt tccaacagat
    30421 caaggaacat actgttcttc gttcttataa aaaaggacag atccttttcg acgatggtga
    30481 tcccagacaa cggttgtata tcttgaccaa aggactcgtt cgtttagaac gttatgatga
    30541 aagtgcaact tattactact atgactatgt gaatacaaat aacctttttc ctatgtcagg
    30601 aatgtttgga gaagagacct acacttatac agctcaagcg atgactgata ttgaaacatt
    30661 ctaccttcct gtttcctact atgaaaaatt agcacgaaaa aatcccgaac agttgatcta
    30721 tatgatacaa aaaatttcta aagtagttga aatacatgaa ttgcgtatcc aaatcggatt
    30781 gacctctagc gcctttgacc gggtaaaaca aaatttattc attttgaaag aagaattggg
    30841 cgtaccaaca aaagatggtc atatcaccat tccttatccg atcaccttaa aagaattagc
    30901 agtgaatagc ggcacgacac gtgaaactgc tggacaagta atcaaacaac tacgtgattc
    30961 cggactgtta gattatgaca aaaagcgttt tactttctgt aagacagcta ctactccagc
    31021 tatgagagaa taacgcgaac aaaaataagc agtgaccctg atatttatca gggtcactgc
    31081 ttattttcct ccctaaaact tctgaaagat ccggcagttt tagatcactg ggcaagactc
    31141 aaagattttc tatgtgtgtt tcagttatgt aatattcact gtttgcaaaa aatactgata
    31201 gattaactag aggaagcgtc ttgtcctcat ccgacctaga ttattcgata ttcctcgaca
    31261 ataaacgatt aatcagtgag ggcaatcaga ggaacggata atgatgaata agctgtaaaa
    31321 aatagggctt tgacaaaagc gtgtcacagc ccttatttcg attaaacggt gtgtacctgt
    31381 caactcttcg gtcacaagtc ataatgttca taaacatgag gagctgtttt ttgaaattgt
    31441 tccttgtgaa tcagagttaa acgacaggct tacgaactct tgattaaacg gcgttcaaaa
    31501 gcttgcatac gcggtaataa gaacagccag gtcaaaaaca tgagaagccg tttttcctgg
    31561 gctgttctta ttacttgatg cagggcagat ttttcacaac ctctttattc agataaaacc
    31621 aagcttggat cagcattcaa ctgatagcta gcaaaatttc ttttttgcat ttccacatgt
    31681 gctgctgctc caatcattgc agcattatct ccacaaagtc gaagaggggg aatcactagt
    31741 tctacctcag ggagtttagt tgccaaagca tcctgcaatc cttcacgcaa cccttgattg
    31801 gccgctacac ctccagctac aatcagttgc ttgactggat aattttgaca agctcgaagt
    31861 gttttagtaa tcaatacatc gatcacactt gcttgaaagc tagctgctaa atcatttttg
    31921 tctagatctt ctccacgctg ttgtgcatta tgcaccaaat tgataaatgc actttttaat
    31981 ccgctaaaac tgaaatcata attatcttca tggatcatcg ctcgtggaaa atggtaatta
    32041 tcttttccct gatgagctag ctgatcgatt tcttttccgc ttgggtaaga aagacctaat
    32101 actcttccaa ctttgtcata agcttctcct gctgcgtcat ctcttgtctc cccaatgatt
    32161 tcatatgatc catcttcttg catatagact aattctgtat gtcctccgct aacaagaagt
    32221 gccatcaatg gaaactggaa tggtttaacc agacgggctg catagatatg ccctgccata
    32281 tggtttacag gaataagcgg caattggtgt gcccaagcaa aagccttagc tgcagaaata
    32341 ccaatcagca acgagccgac aagtcctggt ccataagtga cagcgactgc cgataaatct
    32401 tctgccgaca caccagcttc taccagtgca tcttccaagc ataaggtgat ttgttctacg
    32461 tgatggcggc tagctacttc aggaactacg ccaccaaaac gtttatgact gtttatttga
    32521 gaagcaacga tgttagataa gatctctgtt ccatttctaa cgaccgctac actcgtttca
    32581 tcacaacttg attcaatcgc cagaatcaat tcttcattca tttcatcgtc tccgttttta
    32641 actttctgct cataatgatc gcatcttccg tcggattgcg ataatatgat ttccgtttac
    32701 ctaatatacg aaacttttct gattcataaa gttttcttgc tgcttcatta gatagacgta
    32761 cttctaaaaa aacatgcagc gaatctttta tttgttccgt aatcagtaat tgtaacaaat
    32821 gccgtgcatg cccttttcct tgttctgaaa ctgcaacagc aatatttgtg atctcgactt
    32881 catctattac tttcgagtat ccaataaagc cacagatctg gttatcttca actaaaagca
    32941 gataatcaga gtgaggctgt tggatgtctg ccaaaaactg cattttcgtc caaggtgaac
    33001 catgtggata agcattttcg ctaatcatcc atacgcattc tgccaagtac gcttcatcaa
    33061 aatctttttt tctgcaaatc aactaatctc actcattttc taaaagtttt atcatatcca
    33121 acgcatcttc ttttgtttca gtgtaatatc tttttttgat cgttgttgct tgaaaaccta
    33181 acttccgata aagtctttgt gcatcttgat tactcatacg cacttctaat gacatcgtct
    33241 cacagcgatt cattatagca aagttctcga tttcgtcaat aagcagcgaa ccgattcgtt
    33301 tacgctgata tgccggtcga acggcaatat tcgtgatatg gcaatctaaa ccgaacgctc
    33361 ttgaaccgat aaaaccaatc attcttccat tatcaaagat acctagatat agatgaggaa
    33421 gcggtgactt caattctgat ataaaggcac tttttgtcca tggcaattcg ccattataga
    33481 cttctcgttc gacatccagc agctctttga tatcttctgt agtcaattct cttagtacgt
    33541 aacgacgatc gatttgttcg attgtttttt ctgtataaat cattttatct tgaaaaaagc
    33601 ttctggcata cgctctaaat tttttcaaca taactttcgt ctccaggtgt gtgcgtctcc
    33661 aaccattttt cttctgcttc tacccgtttt aaatagcgag gaagaaaagc ttgtttctct
    33721 gcaactggtt cagctaaagc acctaattga gccacagtta caccacttgg aatatcccat
    33781 gctggaactg tattaatcat cgcactaggc aatatttcct ttatttcata gaagaatttg
    33841 tgacaatcac tcccgacgaa ataaatagct tcattcagct tttgtagttg tgtgaacaaa
    33901 tcagaagcag aaatatgtac atcttcaagt acaatttcta atctattttc tttccagcgg
    33961 tatgccccag cgtatacatt ttttcttcga gcatcaaaca tgggcacaat aattttatcc
    34021 acaccgatgc aattagccgc gatggttttc agactagata ctcctactag ctctttatct
    34081 aatgtataag caatcgtttt tgctgtcgtt acacctatac gaagccctgt ataagaaccg
    34141 ggaccatcag aaaccgcgat tcggtcaatg tcttttggac ttatttgaag atctgcaaac
    34201 aattggtcga ttgcaggcat cagtgttaca ctgtggttgc gtttgatatt tgtttgtatt
    34261 tgtccaagaa tttgttcgtc ttctaccaca ccgatcgcca aagtttggtt tgcagtatct
    34321 attcctaatg taatcatata tttgatcctt tctgctatga cattctcgcc ttccattgta
    34381 gcatactttt ttattctgag gatgaaaata ccaaaggcaa aactagtaca atgatacatg
    34441 attatctgct ggcgggcaaa ttttgcccct tcctgaaaca caaaaaagct gcggtatcac
    34501 ttcatttccc cacagctttt ccatctttta tttcgttgat tctcgaataa tcaactctgt
    34561 ttccacaata atctttcttg aaaccggtgc tttggaatta cttaattgaa gaatcgtctc
    34621 cactgctagc tctcccatcc attcggtata aacttttaca gtagaaagag agggcgttac
    34681 atatttcgct acactgacat cattgaaacc catcacagaa atatcttctg gtaccactaa
    34741 acctttttct tgaatcgctt tcagtgcgcc aatcgctaat gcatcattag ctgcaaaaag
    34801 cgcatcagga acatgcggat tcgtttttaa atactgcttc actgcttgat atcctgactc
    34861 gacagaaaaa tctgcttcga taattggacc ttcgtcgtag cctttttctg ccaaaacttg
    34921 ttgaaatgcc ataattctgg gatcttttag ccgctgatgg tttttcttcg tatattctgt
    34981 tccagcaagc atagcgatat gttgcgcttt atgggagaca aaatgttcaa tgactttttg
    35041 aacacttgac ttaaagtcga caactagaga gtcgattcct tgagaagtgc cgtcagaatc
    35101 taccaaaagc aaggcatttt gggatccttt catttctaat aactgagctt cgtcgaattt
    35161 tcctagtgcg atcgttccat ctgtcggaag atcactaatg gaatcccacg tttctttcaa
    35221 taaagtaacg tttgcttctt ctgccttttt ttcgattcct agacgaatag ataaataata
    35281 aagatcttca agctcttccg tatcgtcgta ccactggatc aggcgaagcg tttgcttagt
    35341 atttgctgca tttttacgat gtttcgtata atttaagcgt tctgctgctt caaaaatttt
    35401 ttgctttgtg gctaagccaa cggaaagatc aggatcatag ttgagaactc ttgaaacagt
    35461 agcaggagaa actcctgcca actgcgcaat gtctttaatt gttgccattt gtctctcctc
    35521 cttttttacg tttataaaat tgcagtaaat cgttcaaacg ctgcctgtcc tttttcatct
    35581 cgcttgaata ctccagcgtc ttccagtaca cgtgcaaaaa cctgacctac agatttttgt
    35641 acgacatcgg tgaccgtatc tttcgtcaaa tcaggatgtt ctttttttaa ttgttctgcc
    35701 cacggacgat gatattcagc catctggttt tcttctccta ataagaaatg ctctacttct
    35761 actagttctg gtttcaaacg aggtggtaaa acagcaagcc ccattacttc gatcaaccca
    35821 atgttctcct ttttgatatg ttggacatct ttatgtggat gaaaaatccc atcaggatgt
    35881 tcttctgaaa cattgttgtc tcgaaggaca aggtccaact caaagtaatt gtcccttctt
    35941 cgtgcaattg gcgtaatcgt atggtgtggt gtaccatctg ctgaaaaagc tctgatagat
    36001 actgtttcat ccgaatatgc tttccacttt tccaatactg agttagctgc ttcaatcaac
    36061 aattttttct ctgttgattg caaacggatc acagacatcg gccatttcac gactcctgcg
    36121 atgacttgcg gataatctgc tagtttgata agtttttcta tcggtgcttt tgccatagga
    36181 aattcatgac gtcctgcctg ataatgatca tgagaaagaa tcgatcctcc aacaatcggc
    36241 aagtcagcat tcgaaccaac aaagtaatga ggcaagactt cagtaatccg aagcagtcta
    36301 gcaaatgttt cctttgtgat tttcatcggg cggtgttgtt ctgataaaat gatcgaatgt
    36361 tcattgtaat aagcataagg agaatattgg aatccccagc tttcaccgtc tagattcatt
    36421 cgaataatcc ggtgattggt gcgggctgga tagttcaagc gacctctata tccttcgttt
    36481 tccatgcaaa gcatgcaggt aggatagtct acttttaccg cctcgcgttc tgctgcgatt
    36541 tgttttggat ctttttctgg cttagataaa ttgattgtga tttccagttc accatactcc
    36601 gactctgccg gaaatttgat gttttttgcg atggctcttg ttttgatgta gtcatttttc
    36661 ttacttaaat taaagaaata ctcagttgct tcctctgggc ttttcgaata gtgctgtgca
    36721 aagaatgcat tgacgactga aggtggcggt gtgagaaaat ccattaattg cgcttcaaaa
    36781 atctcttgtt ctgctggcaa ttctgaaaga acaccatttt ctcttgcctt agcgacaagc
    36841 tgatccaata agtctacaga ttcttcctta actggtctta cttcaatgct ttctagagca
    36901 tcttctccta ccatccctaa aagacgattc tgtaaatata agcggtccat ttccatccat
    36961 ccgccagctt cgatcgcaag tgtggcaaaa tcacaaatcg tttgactgat tgacatatct
    37021 cattccccta ttcttcataa ccatttggat ggctgacatg ccaatcccat gctgttttga
    37081 taattgcttt gatatctgtg tattcaggtt tccaacccag aacctctctc gctttttcac
    37141 ttgaagcgac taatcggcta ggatctccag ctcttcttgg tgctatttct gctggaattt
    37201 cttttcctgt cacttctcta gctgcttcta gcatttcctt gactgagtat cctttgctgc
    37261 tgcctaaatt gaagaagttg ctttcatttc cttctttcaa gtattccaaa gctaaaatat
    37321 gtgcagcaat caaatcttct acttgaacat aatctctgat acatgttcca tctggtgtat
    37381 cataatcgtc tccataaaca gccaatgctt ttctttgacc aagagctact tgtaaaatga
    37441 ttgggacaag atgcgtttct ggtgtatgat cttctccgat agatgcatct gcttttgctc
    37501 cggctacatt gaagtagcgc aaagcgacat agcgcatgcc atatgcttgg tcacaccact
    37561 tcatcatttt ttccatcatc aatttacttt caccatacgg atttttagga ttagctggtg
    37621 tatcttctgt gattggagac tcttttggtt ctccgtaagt tgctgcagta gaagagaaca
    37681 cgattttatt cacattgaac tcgtgcatga cttcaagtaa gatttgcata ccgtatacgt
    37741 tgttgttgaa atacatcaat ggtttttcga cagattctcc tactaaagag cttgcagcaa
    37801 aatggattac tccttcaatc ggttcctttt caaatacgga acgtagaaat tctttatccc
    37861 ggatgtctcc ttcataaaaa tgagcatctg gatgtactgc ttgtttgtga cctgtgagca
    37921 aattatctac cacagctact tgatacccct tttgaactag ctggtctaca gcgtgcgaac
    37981 cgatataacc ggctccgcct agtactaaaa ttgtcataaa aaacactcct ttgattagta
    38041 aaattgtgtt tgttgattat atataattta aaaaaacgaa gtttactttt atggtgaaaa
    38101 caaacaaagt aaaatttcgt aaattcatat ggtaaattta taataaaaca tttagtaaac
    38161 attttcaagg attttttgca aaggtttaca aacaaacgta aaactagcct ttttttctct
    38221 tttgttccat aatagatata acaaataata aatgaggtgg attcaatgaa aaaatttgta
    38281 tctggaatat tagtaggaag tctggcaaca gccgctgccg ttgctggttt ggtcgcttct
    38341 gtgaaaaaaa cagtgatcga tccaattgac gaaaaagaag caatgatcga agaaaaccgt
    38401 aaaaaagcaa tgcgcaaacg cgtttctcgt taataattat ttaaaaacac gcatgaagac
    38461 ttgtgaaaga acagataagt catcatgcgt atttttattt gtcagtcaat ataagttgtg
    38521 ctattttatc tgcctgtctc agattccatg gatctgtata aggtctagct actgctgcag
    38581 ttagccaatc cacaccttca acaggtattc catagcaata aaagtcagac tggatttccc
    38641 ctgaagcatc aatcacgcga ttcgtacctc gctcaacatc tatagcttct gaatgataac
    38701 ttcctgtatt atctgaaaat gaaaaagggc gaacaagttt gttttccttc aaatttttta
    38761 tgacaggatt acttgaacga gaaaagcttg tttgtggcaa tcgagcttca atcaaatagc
    38821 gactgctgat ttctttatct tgtagagaaa taacatagcg gttgtgcttt tgctgaatat
    38881 caaatggcgg ttcgaacaaa tgaaaaatac ccgcatctat cagtgctgct aattctttcg
    38941 tccgaatgac tggcggaccg atcgttaaaa agctatttag atgagtaaac catccccata
    39001 gtatttcttt gtattccttt gcagaaaaaa cgtgccattc aatagcctgc cggattggat
    39061 cacgccagtc ttttaatgca tcaaatgttg aagcaaatgc tcctgtgcaa ttgccttttt
    39121 ccgcttcttt tatctgccct tcaataaatg ctcggctagc ttctgcaaag gactcatcct
    39181 gataggtaag aggaatttct aaatacgacc aatcccatct ataagggatt agtgctggat
    39241 gctttccgag acactcctct gaagagaggg agagaaaatc atgctcaaaa tttttctttg
    39301 gaatcggcaa atgatattct tcgatgattt tcttgtaata aaacaactca acgtcttttt
    39361 tcagatagtc aaaaaatgtt tcgccagtca aaaatcccga ctgatgccat tgctccaggt
    39421 tttcttttgt tagtaaccgt ggccatgcca ttgatccgcc ttgcttttgg tttcttcctc
    39481 gagggtaata agggagcccc cttcttgatc cactgtatac aatcggttcc ttgcctgatg
    39541 gatgatagac aagttttcct ttttcgttct cgaagcgccc ttctcttgat actgtaaaca
    39601 atccgacata atcaaaaaaa cttaagccta gacctcttaa aaagacattt tctttaggcg
    39661 gtatcttcga aagatcgaca tctgcaggat tagaaggaag ctgatacagt aaatcatttt
    39721 tctttgcgta gtctacccac actctttctt cttctgtctc atcattttcc cagtgaccgc
    39781 ttgctaaaac aagctgatcg atagaatagc tttgctgatc tgtctgtaaa agataaccat
    39841 cttttctttt gctgactttt tttactaaag aataaacaaa ctgaatagaa gctggaaatt
    39901 cttcttgcaa ctttgagaaa aaccagcgtt gatagagtcc gtataaacat cgagtagatt
    39961 gctgatcttt ttccagacga ttgatttctt ctataattag ttgcttattt ttggttaccg
    40021 tctgttcgat ataatctgta gcaggtcctt tactccattg aaacaagttg ggtccctgtg
    40081 ttaccaatcc tccactggac aatgtttcat ctgtaaaaag cgtcacttgt tgagaaacag
    40141 aattcattaa taactccggt ggctgattca accgccaaac tcgacctcca ggaccattgg
    40201 gatcgaaaag aaaaagttca agagaatgtc tgtcctgatt attatggaga atcctttctg
    40261 ctatacttaa tcctctaggt ccggcaccaa tgatccctat tttcatttgc atgcctccat
    40321 ttcgataaat tttttcaata aaacagcatg gttctgatgt tcattttttg caccataaac
    40381 aaaagtaatg actggatgtt ctttcataag ttgactgagt ttaaaaatag cttgcttctt
    40441 ttcttcttcg aaaatcaatt cttgctggta tttctttgca aatgaagcaa atcgttctgg
    40501 tacatggtca aaagttttgc gtgcttcatt actaggtgca atttctttca accacagatc
    40561 taactgcgct ttttcttttg aaattcctcg tggccagaac ctatccacga gtattctata
    40621 gccatcctct ttttcagcat caaggtaaac acgttttaat ttgatcatag ttgtttcctt
    40681 ctttctgcct tttcgcttag cttatatatg tagataatag cacaaaataa aaaaaatgaa
    40741 cggcacaact atccattgcg ccgttcatgt gatcttggtc aaaatctaat gattgattcg
    40801 gtttttaaag ctgtcataca atcatctgtt ttatactttt ttacttttga tttttccaga
    40861 ccatccgtca tatccaccct taagtaaata aatctcttga taacctgctt tacgtaattt
    40921 atttgctgta cggatgctca agcttttctt ttgatcgtaa atatagacag gctggtcttt
    40981 tcgaatagat cctaatgaat ctttcaaaac agtgtaaggg atgtttcttg cacctaaaat
    41041 atgcccagca tcaaacacat ctttttcgcg aacatcgatt acttgtgctt ttctcattcc
    41101 ttctcgaaat tcttcttctg tcaaagtcgt tgctgaacgc ttggccatta ctcgtagata
    41161 gacttcccaa aagatgattg caagcacaat caatagcaaa atgatattaa ttacccataa
    41221 aaccatgtaa tgcctccgtt tttttaagca aatttcaagg ctaatgaggc agcaccaatg
    41281 acaccagctt cattaccaag ctctgctaat ttgatttttg ttgattctct tacttgcggg
    41341 aaagtaaatt ctttaaaata tttctctaca cggctacgta aaaattctcc tgctgccgat
    41401 actcctccac ctaacacaat acttgacgga ttcaatgtat tccccaagtt ggcgcaagct
    41461 aaacctaagt agaagcatac gcgatcaaca accatcaatg caaacggatc gtcttcttga
    41521 gccatttcaa agatatcttt acttgttact tcttcaccgt tgtctaacat tgctttcagt
    41581 tttgaatctc ctgcgtattc ttctgccaag taacgaccta gacgtaccac accagtagcg
    41641 ctagacacag tttctaaaca tccgcgttta ccgcaagtac attcgaaccc ttcaggatcc
    41701 acagtgatat ggccgatctc tccgcctgct ccgctcacgc cgtgaatcaa atttccgcca
    41761 gcaacgatac caccgccaac acctgttcct agagtaacga atacaacgtc tggatcgttt
    41821 tctccagcac ctttccatcg ttcacctaaa gcagcaacat tcgcatcatt atcgatagcg
    41881 aatttgattc ctgttcctgc ctcgatcagt tttttcacaa attgaacttc tgtccagttt
    41941 aagttatacg caccaataac cgttccagct tcgctgtcca cgcttcctgg ggtacccatg
    42001 ccgattccga taaagtcttc ggctttcata ttatataaat tcaaacgatg gttgattgat
    42061 tcaatgattt caggaacgat atgcttacca tcatccaaaa tattggtatc gatgctccat
    42121 ttttgttgaa tctctccttc tggtgttaaa attgcaaatt ttgctgttgt tccacctaaa
    42181 tcaatcccaa taatcttctt gtccattaca aatttccttt ctttcggctt tcttcaattc
    42241 ggtgctctct ttttaatatg cgccacgctg tcatgtatgt atcatgatca atcaaacggc
    42301 tatcatacag attacgcaat tcgatagtca ttaattcaat gtcatagatg cgtgcaccca
    42361 catagataaa gatgccaaat tttttgaaca gctgctgtac atcatataag ctctccatct
    42421 ttaagcactt ccttcatatt atacaagtaa accatatttt tttaaaccca gtaaaataca
    42481 tattacaaaa agaaatacaa aaactagtgt agaaagaatc ctttggtgta tcgaatagct
    42541 tgtctgttgt ttcggtagac ccaaaacatt ccctaacact aatccgccaa ttagcccacc
    42601 gacatgtccc caaacatcta cagaggtatc cagaagacca aaaacaaatg tcaacacaat
    42661 aaataaaaga aaatgtctga ctagctgctg gatcgctggg ttatgtttaa aatgaaaccc
    42721 taagataaac aacgcaccga acaaaccgaa tatcgaagta ctcgcaccac cagacagaac
    42781 attcgcttcg ttaaaagcaa agcttgctgt atttcccatt atcccgctga acatataaat
    42841 caagaaaaaa cgccaatggc catagattgc ctcgatttgc tgccccataa aatacagtat
    42901 cagtgagttc attacgaaat gcatcagtcc aaaatggatg aagattggtg tcactaaacg
    42961 ccaccattca ttgaagtgaa caagataagg accatacatt ccggcataat aagggatctc
    43021 aagtcgcgga aataattcca tcatgaggaa gaccgctgtc tgtatcccta aaaaagcata
    43081 ggtccataac ggtcgtctta accatgcacg caattttatt tgctgttgat aattcatgaa
    43141 aacctcccat ttcattttag tcaataaaca attgttggat cttctgatca aagctctccg
    43201 gttgccattg ttcattcaat tgttcacgaa aaacaaggct acatgttttt ttatgaaaat
    43261 tatttaaata ccggtcgtaa taaccaccgc caaaaccgat tcgataaccg gctctattgt
    43321 agataatacc tggtacaatg aggagatcga tcatctccgg caaatagagc ttctctgatt
    43381 gtggctcaag aacaccaaaa ctcgaacgta caagaacgga ctgttcatcc atttcataaa
    43441 acgccatctg acgtttcggc aaagttttag gtacaactat tttcttttgt tctttttctg
    43501 ctcgttggat aaccggctgt gtatccagtt caaattcatt cgataaagtc gtccctatca
    43561 cttttgctga cttccagtac tcgctggcga atagctgttt atagattcgc tgttcttttt
    43621 cctttttctt gccacttttg gccagatttt tcagcttttc gattcctttc cggcgtaatc
    43681 ttactttcaa ttggtccaaa aactcaccct tccttctctc ataaaatggt ataggaaaaa
    43741 aagaaaaata gcaatcgaac tttcaaataa atgcataaat agaataaaaa gaagacctag
    43801 aaatgattgg ccttcctttt ttaataaatt tcaactgttc agcgcgtgtt tttgtctgat
    43861 aaaaagtgca tacagaaaat atggcgcacc aaaaagggca atcaaaattc ctgtaggtac
    43921 ttccccactt ggtagaatca ctctagcaac catatctgca ctaagcagaa aaatggaacc
    43981 gaacaaaccg ctcagaacaa aggtccagtt attttcttta cgtacgacta gcttcgcagc
    44041 atgaggagct agtagtccta caaaagataa actacctgtc accgctacac taccgcttgc
    44101 caaagcaaca gctaacaaca aaaggatttt ttgactttta gccacgttaa ggcctaatcc
    44161 ttgcgcgcgt tcttgaccaa atgatagcaa tccaatcctc tgtgcataaa gtcctcctag
    44221 cggaattaag ataaccgccc atggaagcaa tgcccaaaca taaggccagc tcgcacccca
    44281 gattgatccc gctaaccatg cattcacaaa tccataattt tccttagata attggatcgt
    44341 gcatagcaat gttaatgcag aaaggccggc attaacggca ataccggaca ataagattcg
    44401 attcataccc aaaaagccat ttcgatcata ggccgcaaga tagacacagc aagcagctaa
    44461 aacaccacct agaaaggcta caactagcaa tagaaacggc agcgaatagt gcgaaaagaa
    44521 acctaaataa agcatcacta aaaatcctgc tccggcatta atgcccaata tactagaatc
    44581 tgccaattca tttcttgtta ctccttgcaa gatataacca gaaacgccaa gacaagctcc
    44641 tgctaataaa ctgatcagta atcgaggaac tcgaaattct ctaacaatca gcgccaaaga
    44701 agatgattct ttccctatga acgtggcaaa aagctgatcc aggtaaataa aaggcgtacc
    44761 aatcattaaa ctacctatag acaggatgac aagtacaaaa agcaagaaat agaacgtcca
    44821 atatattttt ttcaccgttg ttccctcctt acttgtatca gtaaaaacgg aacgccaatc
    44881 aatgcaatga ctaatccaaa aggtgtttca aaagggggat tgatcatcct cgctgtaaaa
    44941 tccgccaaca taaccaatcc accgccaact aaaaaagaga caggtagaac ataacgatag
    45001 tccgttccaa ccattccgcg aacaactggc ggaaccaaca gcccaataaa tgaaacaggt
    45061 ccgactaacg aaacggcaat ggctgctaac actgcaacta gacagaaaac aatcaaccgc
    45121 gttcgtttag gatgacttcc aagagctaat gcatgtgttt cactcaaatg aatcaaagat
    45181 attgcttttc ctaatgaaaa agaaaccaaa acagcaagta tatataaagg aaacaatact
    45241 gctaattgtt tccatgtgat attggcagct ccgcctacaa accaaaaagc aagatcctgc
    45301 tgcagattaa agaattgggt aagtgcttgg ctgatagcag taaaaaaaga actaatagct
    45361 acgccagcta aaatcagctg taaaggattc atgcccattt tcgaaaactg caaaaaacca
    45421 aatacgagca aagttacagc aaaagaacct gccaatgaca ttagaaacac agaaaaatca
    45481 gaagctttag gccaaaaagc aaaactaagg gccattgcca acgaagcacc cgcgttgatt
    45541 cctagtaagc ctgaatctgc taaaggattt cttgtcactc cttgcatcaa tgcaccgctc
    45601 aatgcaaaac aactccctac aagaaatgct cccgccacac gaggcaaacg aatatttcgt
    45661 atgatttggt gactttgttt tgatctatca aaatcaaaca acgcctgcca aaaatctgct
    45721 tttcccacag tcgctgcgcc atttgaaaga gcaacaaaaa aaataatcaa aagaacaaaa
    45781 cagaccaaaa gcaggagtct atttttcttc atagtcctca taattgatcc tcctgctctt
    45841 ttggcaacaa atcataggtt agaaaaactg gtttatttgt tcttggaagc gtgacaatcg
    45901 ttgcatcaat ctcaaatatt tttttcatac actcttttgt gatcacttct tcaggtgtac
    45961 cttctgtgat caacttaccg tttttcattg ctaataaata atctgaaaaa cgtgaagcat
    46021 gattaatgtc atgaatcgac atcaagatcg ttgtttgttt catttgattg atttcagtca
    46081 ataactgtag gatctctaat tggtgtgccg gatctaaaaa tgttgtcggt tcatccaaga
    46141 tcaagatatc tgtttcctga gcaagcgcca tagcgatcca gacacgctgg gtttgtccac
    46201 cagacagcgt tgcgatatcc cgcatacgaa atccagctag acctgtagca tccaacgccc
    46261 actcgattgc ttcatgatct tgcgtgtcca tgccactgaa cagtttttga taagggtatc
    46321 gtccgtaaga tactacttct tctactgtca tacctgtagg gtgttcacta gtttgtgcta
    46381 ataatgtaat tttttttgca agttcttttg aactgtatgt agagatatca gagttattga
    46441 caatgatctt tcctgatttc acaggtagta tacgggtaaa acttttcaat aaagtagatt
    46501 ttccacttcc atttggccca atcaaactag tgattttccc ttcaggaatc gtaacagaca
    46561 tgttttcaat gatttttttg ttttcgtagc cggctgcaat gtcagctgct cttaatctcg
    46621 tcatttcacc catcctttcg ctgaaaatca ttctcaatta tgacgctgtt tcaacatttc
    46681 gtcaagcgct actttcatat ctatagccaa atgaagcggt tgacagcgtt cgaaatatca
    46741 ggaataataa ccaatgagaa agattctcaa ttatgttagg aggaaagaaa tgaaattaaa
    46801 aacaaaagta ttcacattat ctagcatatt gctgctggct ggagtactga gcgcttgctc
    46861 cccctcttca gataaagaaa cagctacaac tgccaattcg acgacttcat ccaatagtac
    46921 tcatacagtc acagatacac ttggacataa agtagagatt ccaaacgcgc ccaaacggat
    46981 catcggcagt tacttagaag actatctgat tgcactaggg gaaaaaccta tcgcccagtg
    47041 gactgttggc agtggttcca ttcaagatta tctgcaagat gatttaaagg atgtcccaac
    47101 gatttcttat gaccttcctt atgagaaagt gttaagcttt gagcctgatt tgctgttgat
    47161 ttcttcttcc gctactgtcg aaggcgggaa atacgaacaa tatagcaaaa tcgcgccaac
    47221 ttatgttgta aaaaacggaa cagatgtcac atgggaagaa caactaaaag atgtcggcaa
    47281 agctttggca aaagaaaaag aggcagaaaa aatcatttcc gattatcaaa aatccatcaa
    47341 gaaaactcga gaagaactag cagataaaat cgagaacaag acagctgcag tgttgtgggt
    47401 gaccaacaac tcagccttta tggtcagcaa aaatcggtca agtggaagaa tcgtatacga
    47461 cgatctggaa tttggtgttc ctgatctagt ggaagaggtc tccaaaaaag ccacttctga
    47521 ctggtctgct gtttcctctg aaaagctagc tgaattagat gctgactaca tcatccttgt
    47581 gaacagtgac aaagatgctg ccatgttcaa tgaaccaagc tggaagaatc ttaaagcagt
    47641 gacagacaat catgtactgc aattcggacc tgaatctagt tggctatata acggacctat
    47701 tgccagtcag gaaatggtca atgatatcaa agaaaaacta aattgatttt aactaaaaaa
    47761 agaatcttca cgattagtcg tgagatgctt tttttcttat taacaaacta gacgcataga
    47821 ttttattctt cttttgaagc aaccctattt tttactcttt cccatttttg aaaacgatgg
    47881 gcatatagat tttcttgatc cgttatcccc tcatactcct ctataagggc gaagtctgaa
    47941 aaatcaatat tcccaatata cgtatcgcct tcaaacgtgc tatcgatcaa tgttcgccag
    48001 atccgaccag tgtaaggaag aagttcttga aaaatccgac taccacccga aacatagata
    48061 tcttctgaga tcgtttgact atacgacaaa agttcatcga tcgaatgcat tacttccgca
    48121 ttttctttcg tgcgaaaatt tggttgcgtt gtcaacacga tgatatggcg ataaggaagt
    48181 gaaagatccc ccattccttc ataggtcttt cttcccatca ctaaaattcg atccattgta
    48241 tgttcgcgaa agaaacgcat atcatttggc aatcgccatg gtaacaaacc atttttgccg
    48301 atcagaccat ttttatcttg tgcccacatg gaaataaaca tattatccgc tccttatgat
    48361 tttagatgtt ttgagataaa aaaagtctca attctttgac cagcaaggaa ttgagaactt
    48421 taaaaacatt attttgtttc acggtgcaaa gtaactttgc gttcgcgtgg gcaatatttt
    48481 tgtttttcca aacgatcagg attgttacgt ttgtttttgc ttgttagata gttacgttct
    48541 ttacaagaag tacactctaa agtgatgttt acgcgcatgt ttttccctcc catttttaca
    48601 agaatcctct aagatgactc tcagacttga ttatcttacc atgatttttt ctagattgct
    48661 agtgtttttc acgattttgt taagtaaaac tacttgacga taaatacaac ggttttactt
    48721 ctcaaacaaa atctttttct ttttgtataa atacccttac acttgtttat atagattatg
    48781 ttttttaata aagggggata ctaatatgcc atggaacatg aaggactttc ctgcatcaat
    48841 gaaaaactta gataaattga caagaaaaaa agcaatcgac atcgcaaatg cattattaga
    48901 tgaagggtac cctgataacc gtgcgatccc aattgccatt gatcaagcaa aaaaatggta
    48961 tgaagatgct agtgaatcag aaaaacgaac tttcgaaaaa gaaaaaaatc caagcaagac
    49021 ggatgaacac gatacgaatc ctcgtgctgg aaaactgctt gattcagatg tgatcgtaga
    49081 atatgaggaa gaacaatgga tcgtgaaatc taaaggggca aaaaaggcaa gcaaccattt
    49141 tgatacaaaa aaagaagcaa tcgaaaaagg aaagcaagta gcacaaaaca aagaatcaac
    49201 tttgttcatt tataaaaaag atgggacaaa agaaaaagaa atcgattatt gaacatatgt
    49261 aaaggggttg tgacgaaaat cgtgtcacaa cccccttatg ttcgaaacaa tggtgttcct
    49321 ctgccaactc cgaaccataa gtcataatat ctataaaacg ggaagagctg ttttttgaaa
    49381 ttgtttctta tcactcagtg ttaaacggta ggagaaaacc tcttttttat tgatatttga
    49441 ttttcatcaa acagtcacat agtcgattgc ttctgcttgc ggaatcgttt catctacaaa
    49501 gtagacttta taccatgtca agaaactgaa gattgtccag atttttcttt gctcttcttt
    49561 acgtccttcg tgatggtcat ctagcaactt catgattttt tcttgatcaa aaaattcttt
    49621 tgcaaaatct gcttcgaata atgctttgac ttgttcgtag ccgtgttctt ctttcaacca
    49681 agctttgatt ggcacaggga atcctaattt cacacgattc gaccattctt ccggaagatg
    49741 tttgttcgca gcttgtctga aaatatcttt tgtgttgttt tgattcaata aaaacttact
    49801 tggtatttgt tgagccaatt tcatgacttc gatatccaat aaaggtactc ggacttccaa
    49861 agaacttgcc atagaaagtt tatctgcctt taacaagata tcttttggca tccattgatg
    49921 aagatcgaca tattgcatct tattgacttc atctttgatt ccttctgttt tctcgtaatg
    49981 aacagtcatg atttcatcca cagatggtgc tgtttgatat tttggtgtta acacttctga
    50041 tgcttctgat tcttcgaaca ctcgagcatg accgataaaa tattcttttg caggagcaag
    50101 tgattcatat aaatggatcc gtccatggaa atttttcatt tttccgattt tacgtcctaa
    50161 attatagcgt gttccttttg gtaatttttt caatccttga gcaatcacac ggatgaattt
    50221 tgaattcgta tggaatccat acgtttggta tcccgcaaac agttcatccg ccccttctcc
    50281 agattggact acccgcacac tttgtgaagc aagatttgct aaaaagtaca aaggtacgca
    50341 agaaggattt gaatcaggtt catctaagtg atactggatc aaagggaatg ctttgaacga
    50401 catgtctccg tcgatcactg ctgctgtatt atctaagtcc aatagttcgg ttagttttct
    50461 ggcttcaatc gcttcattat aggttttatc atcaaacccg attgagaaag aatgatctgg
    50521 tttcaataca gaggttacat aactggaatc aaccccgctg gataagaaag aaccaacttc
    50581 tacatcactg accgtatgtg cttcaataga agcttgaacg gtttcgtcga ttttttcgat
    50641 ccattcttgt cgggaatgcg tttcttttgt ttcaaaatct gcatcccaat attgctgaat
    50701 gtctagtttt ccatctttat acgtataata atggccttca ggcaaacgat agacatcttt
    50761 gaagaatgtt tcgccgttta atggagaata ttggaaagtc atataaggtt tcaacgcttc
    50821 tttgttcaat tctttgttaa aatcaggatg aggcagaaaa cttttgattt ctgaaccaaa
    50881 cataaatgtt ccgttcattt ctgcataata atatggtttg atcccaaagt ggtctcttgc
    50941 accgaataac tcattctttt cattatccca aatagcaaaa gcaaacattc cgcggatctt
    51001 ttgcaataat tctgttcccc attcttcgta accatgcaaa aggacttctg tatctgcatg
    51061 tgtttgaaaa acgtggccag ctgcaatcaa ttcttctctc aaaggctggt aattatagat
    51121 ttcgccatta aaaataatga tctttgtccg atcttcattg taaataggct gagtaccgcc
    51181 ctctaagtca ataatactta atcttctgaa tcctaaagca acatgtttat cgatatattc
    51241 tcctgaacta ttaggtccac ggtgaacgat tcgatccatc attgtattaa taattgtttt
    51301 tttgttgtcc ttgtcgttaa caaaacctac aataccgcac atttaacttt cacatcctaa
    51361 tataaaatta ctgtttattt cattcatatg catcttatca tagaataaat agcggacgaa
    51421 tattttctct cttacaattt cgtcacgtga aaacaaaaga tgaaagtttc tgtttttaca
    51481 gaaaataaag tcccaatatc taatttacca tgttttcttt tttgaggcta ccttattctc
    51541 ttcgtgttaa aaaaatatta gtggatgcta tttccaaaaa aaacagcaaa aaaagacacg
    51601 acctaaagat cgtgtctaat tatgactgta tcagaaaata tgataccaaa cggatctatt
    51661 cattaattaa ttgacatagt ttatctgttg ctcttttatg actggataac tgaccaattc
    51721 atgacgatcc aagtcttctt tatttatatt tacagcagta atttgactgt cttcatacgt
    51781 acgataataa taaatccctt tatcaacgtt acagcaagaa gaataaatcg tatattcgta
    51841 ttttccttct ccagtatcgc atactccttt ttgttgctcg actgagccta gtatatgaaa
    51901 aaattgactg atactttcag attctgaatc acctgatgca gcattcattt tagtaaatgt
    51961 ggcttttaca aatcgagaaa cagaagagag atctccaggt aagcccaatc ctcccatccc
    52021 acgactataa acattcaagc tgatctggtt tgaaaaatga ttttctggtg ttccatttga
    52081 tagcgagcga taattgttca gattaaataa ttgataatca aatggcggat tatttgtcaa
    52141 cacaccgaca ggattatcat ataaatgaag tccatctttc atactttcaa ttactatcga
    52201 tttttcttta tcagctaata accagtgtaa aggtgacaag ggtagttttt cactaaaatc
    52261 gatattgact agattgatag tagccaataa ttctttagct tcgtctatgg ttgagcattg
    52321 ccctagtatc catggaataa actcaaatgg tgcaacgtta tcttttcctt cttgtaattc
    52381 tttataatca gcattgccag gaaaattcag tcctgccata ctcaaccctt tttcatttgt
    52441 agcctcataa tagagtggat agttggatac cccagctgct attcctatca ttgcataatg
    52501 tttatctaaa ttttttacct ttctaaaatc gaaacgataa tttcttggag taatagtgac
    52561 tacttcatta taagacatct cataatcaaa attccttcca aaataatggt ctttcgttgc
    52621 ataagtgatt gcggtacaca tcgttttccc tcctaaaaca aatcgttttt acacttttat
    52681 cttacatcta gtattttttt ttatcaaaaa aaaggccaaa gaagattgat ttactagcat
    52741 ttataaaaaa tagtactcag ggggaatcaa aaaatattgt aggttaaaag tacaacaata
    52801 aggggctgtg acaaaagtct tgtcacagcc ccttattccg aacaaacggt gttcaaaagc
    52861 ttgcatctgc ggtaataagc ccaaccaaac gaaaaaatag gaaaagctat ttttgtttgg
    52921 ccgttcttat tacttgatgc aggacagctt cttcacaacc tctaatcgtt gatataagga
    52981 aggtacagga tttgaacctg cgcgccggta ttagccggtt cgccggattt cgagtccggt
    53041 gcattaccac tctgccaacc ttccgtaagt actattttta aacttttttc acgaaatgtc
    53101 aagcctattt ctaatagata aataacagaa atcgcttttt ttagcaaaaa agtccattga
    53161 cagtttgcag ccaacggact taccgatcaa attcatactg atagaacact atctgattat
    53221 ttcaggatta tctaatgcta aaatcgagtc aattgtccgt ttgatcagtg caatgatttg
    53281 ttcttctgtt ggatgcatga tgtttgatga catcaatgac gctaagccag tcactgctac
    53341 ccatgtacca gtatgcagag catcgacata ttcatccgat aattgattgt atctttcatc
    53401 ttctttaact atttcacgga aataattgta tgaaaaatca tgcattttct ttccgtcccc
    53461 atgttcatca atgtacaatg ccatgtaaag actatgatgc ttttttgcaa agtagatata
    53521 gttcaaaccg agatcaatga ttttatcacc agtacgttca atagggaaaa catcttcttt
    53581 tagttgttca aagatagaat ccagcaacgt attttttaaa tcttccatgt ttttgaattc
    53641 cagataaatc ggctgtgtcg aaatccccat ctttttagca atatttctcg cagtaaatcc
    53701 tttaaaccct tcctttgcaa caacatcata agcagctttt agaatttgat ccttggtata
    53761 gacttttctt ctcattaaaa ctcccccact tctttactgc agtatatgtt gttttattgt
    53821 accctatttt tagcattttt tgcaaacatt ttactcaaaa cgttatattt taaatttttt
    53881 tcagtcttct ttaacttttt tttgcaaaat taaaaaaatt tggttaaatt caatgggttc
    53941 ccttacattt ttagttttga cctaaatgat agttgtccaa atctttcatt tcaagttata
    54001 gttaaagaaa atgaaaaaga aggtgtgtaa tggaaaacga aactgacgtt atttatattc
    54061 atcctcaaaa acgaatcgtt tcacagaaaa gaaagtattt ttatcttggt tttacaggtg
    54121 ttttttttct ttttattggc ttgctttcta atactcctac tgataattgg agtggattgc
    54181 taactattct tacctcgcca agcaatcttt tgacagatta ttttgcttta ggtgttttcg
    54241 gaagcgcatt cataaatgta gggattttga ccttactttc tgtgctttta gcttatcggc
    54301 acaaggtgat tttaaacggt cccttatttg cttcgattct aacagttacc ggtttctctt
    54361 tttttggcaa aaacctttat aattctatct caatcatttt aggtgtgtat ctatacgctg
    54421 tatttgtcaa taaacctttt tctcagtaca tcatgatcgg actgtttggt agcgtattat
    54481 caccggtcgt tagttatatc acttttggta tgcgttttcc tttactgata ggtattttat
    54541 tggggaattt agctggcata gcaattggta tacttcttcc gcccttagct gctcaaactt
    54601 tagttttcca tcgtggattc acactttata atattggatt cacctctggg ttgattgcga
    54661 tgacttttac tgctgttttg aggttattca gctattcaat cgtcgaaaat acattggttt
    54721 tcaatgaata tcactttcct ctcatttgga ttatttttgg ctttttttcg ctgacagtcg
    54781 gaattggttt ctattataat tcctttcggc tttcggggat tcgagaaatt ttcgattcat
    54841 ctggaaaatt gacaactgat ttcattgcta attctggtat tggtgctact ttgatcaaca
    54901 tgggcttagt tggtctgatg ctgtcttctt atgttttgct ggttggcggt cagttaaatg
    54961 gacctgtcat cggtgctatt ttatctgcgg tgggtttcag tgcttttggt tgtcatttaa
    55021 aaaacagttt tccgatacta gtcggaatat ttattgcttc tttgtttgga acttttcatg
    55081 agatcaccag tactggcatg cttgttgcag ctgtgtttgg gacaggtctt gcgcccataa
    55141 gcggttttta cggcagtttt tacggtgtaa tagctggtgt gctacatatt gctcttgtcc
    55201 ataacgtcag cactttgcac ggaggactaa atctatataa cagtggtttt tcaactggtt
    55261 tcgttgcagg tatccttgta ccgatactag ataactttac cgctgtcaga aaggaaaaaa
    55321 agacacttgg aaaaagaatt atcaaaaaga atcatcgatg agcttcttac ttatttatat
    55381 tcccatgaaa taactgaaat acgtattgga gtagaatttg ctgaggaagg gcttttcata
    55441 gagatacagg gtacggcaga aactcagcca gaagatttag atgtacttgc tgatttgctg
    55501 aacaatcctc gggaccctag tatggaaatc tactatcaag aactattagg taatccccga
    55561 catgatcggg aagattatca tctgttaggt agtttgattg atgacgtgga aatcatgtat
    55621 gcccagccga ttatcaatat taagatcttt cgacgtgctt ctcattccta ttattaaccc
    55681 tattttctat ttataaaaga ctgaatcaaa aaagcagctc ctgaaagttc gattaaaatc
    55741 tactttcagg agctgttcaa gcttgacatt attgattttc caatccttca tacacttcat
    55801 ctgttacagg ttctaaaaac tctgaattac cagcagtgat cgccaaatgt tcaaaccaac
    55861 tgtcttttgt cgcaccatgc caatgtttaa tccctttgtg cgttacgacg acatctccag
    55921 ccattaatcg tcttgctggc tttccttctt cctgatacca gccttctcct ccggtcacaa
    55981 gtaagatttg atagccgtct gtatggacat gccagtgatt gcgacaacct ggttcaaaag
    56041 ttacattacc tacaccaaca gaaacttcgg gatcattcac taacatattc agatagcttt
    56101 gcccggtaaa tacttgagcg taagcttcgt ttttttcacc tgctggaaaa atcacgccat
    56161 tgtgtatttc ttcgtgtttt gtcatcattt acgcctcttt cttatcttcg ctattttctt
    56221 ctaaatagat ttcttttgct aaactaaaag ctgaccaagc ttttggccat tctacataaa
    56281 aagctaaatg ggtaatgatt tctgctattt cttcactagt aatgccattt tgcttgccaa
    56341 tcttcagatg agctggcaat tgttcaaaat ttcctcctga aattaatgca gatatggtga
    56401 tgatactacg ctgatgagca gataattctt ctctggacca tacttgtcca aataaaacat
    56461 catcatttaa ttctgcaaat tttggtgcaa aatctcctaa ttgatctcgt cctgcggttt
    56521 gtttttctgc catttctctt attctccctt cacgactgtt aggtgattca actatggttc
    56581 taaggcaact ttattttcta ttgtttcttc gcatttcatt ttaaatgtag tctttcagcc
    56641 tgtccaatgc ttagtttatt cagtcgatat gctttttaag catagttgct aacgcttttt
    56701 ttattttaaa aaaaacaagt tattaaataa gtctttagtt ggatgttttt ttgagatcaa
    56761 tcttttatac ttatgatgaa cttacaaaat tgtttgtttt ctgtcatatc aaaaaatggc
    56821 gcagttagtt gcttttctag taaagtatag ttaacaaaga acctctaagg agttgatgaa
    56881 taatgaatat tgctgcctct cgaaaactga taaatttcat atccattatc ggattaggcc
    56941 tatcaatcgc gctgacgatt tattttatta atttaggtgt tttcaaagat ttgaatgcgt
    57001 taagaggatt agtaggtgat tccatcattt taggaccgat tatttttgtc ttcatccaaa
    57061 tcctgcaagt agttattcca atcattcctg gagggatcag tactgcagct ggtgtcctga
    57121 tatttggccc ttatgctgga tttatctata actatattgg aatctgcatt ggttcgatta
    57181 tcatttttct gctagggcgt cgttatggaa agccattcat actttccatg attagcgata
    57241 agacatataa caaatatatt ggctggctgg ataatcaaaa ccgttttgag aagctgtttg
    57301 ctctagctat ttttcttcca gttgctcctg acgatgcgtt atgtttgatg gctggattga
    57361 caaacatgtc agtgaaacga tatacactaa tcattttgat tgctaaacca ctgtcgattt
    57421 tcttatatag tatggccttg atttatggag gtcaatatct aagtggtctt cttggataat
    57481 atttattttg taaaattagt cattgattga caatgtt
//
LOCUS       DAYYEF010000012        56215 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000012 DAYYEF010000000
VERSION     DAYYEF010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.012"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            157..1002
                     /locus_tag="ACHA1B_000871"
     CDS             157..1002
                     /locus_tag="ACHA1B_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM8701653.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1283..2503
                     /locus_tag="ACHA1B_000872"
     CDS             1283..2503
                     /locus_tag="ACHA1B_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFM8701654.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2500..5220
                     /locus_tag="ACHA1B_000873"
     CDS             2500..5220
                     /locus_tag="ACHA1B_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM8701655.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5204..6148
                     /locus_tag="ACHA1B_000874"
     CDS             5204..6148
                     /locus_tag="ACHA1B_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFM8701656.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6217..7227)
                     /locus_tag="ACHA1B_000875"
     CDS             complement(6217..7227)
                     /locus_tag="ACHA1B_000875"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFM8701657.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7407..7751)
                     /locus_tag="ACHA1B_000876"
     CDS             complement(7407..7751)
                     /locus_tag="ACHA1B_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HFM8701658.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7744..8178)
                     /locus_tag="ACHA1B_000877"
     CDS             complement(7744..8178)
                     /locus_tag="ACHA1B_000877"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HFM8701659.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8316..9053
                     /locus_tag="ACHA1B_000878"
     CDS             8316..9053
                     /locus_tag="ACHA1B_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701660.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9046..10257
                     /locus_tag="ACHA1B_000879"
     CDS             9046..10257
                     /locus_tag="ACHA1B_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8701661.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10461..11243
                     /locus_tag="ACHA1B_000880"
     CDS             10461..11243
                     /locus_tag="ACHA1B_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HFM8701662.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11313..11975
                     /gene="trmB"
                     /locus_tag="ACHA1B_000881"
     CDS             11313..11975
                     /gene="trmB"
                     /locus_tag="ACHA1B_000881"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008176 - tRNA
                     (guanine(46)-N7)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HFM8701663.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12073..13827)
                     /gene="ade"
                     /locus_tag="ACHA1B_000882"
     CDS             complement(12073..13827)
                     /gene="ade"
                     /locus_tag="ACHA1B_000882"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000034 - adenine deaminase activity
                     [Evidence IEA];
                     GO_process: GO:0006146 - adenine catabolic process
                     [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HFM8701664.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            13959..14888
                     /gene="comGA"
                     /locus_tag="ACHA1B_000883"
     CDS             13959..14888
                     /gene="comGA"
                     /locus_tag="ACHA1B_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus ATPase ComGA"
                     /protein_id="HFM8701665.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            14845..15894
                     /gene="comGB"
                     /locus_tag="ACHA1B_000884"
     CDS             14845..15894
                     /gene="comGB"
                     /locus_tag="ACHA1B_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus assembly protein ComGB"
                     /protein_id="HFM8701666.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            15891..16169
                     /gene="comGC"
                     /locus_tag="ACHA1B_000885"
     CDS             15891..16169
                     /gene="comGC"
                     /locus_tag="ACHA1B_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030420 - establishment of competence for
                     transformation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus major pilin ComGC"
                     /protein_id="HFM8701667.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16144..16614
                     /gene="comGD"
                     /locus_tag="ACHA1B_000886"
     CDS             16144..16614
                     /gene="comGD"
                     /locus_tag="ACHA1B_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGD"
                     /protein_id="HFM8701668.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16586..16933
                     /locus_tag="ACHA1B_000887"
     CDS             16586..16933
                     /locus_tag="ACHA1B_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701669.1"
                     /translation="MVAIQKELNKTGFVLLESLTALMIASVCVYLVSFGQLFLLQAEK
                     KSGEELLFIRMIYEDIKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAI
                     SIEKTSNSSIYAD"
     gene            16896..17321
                     /gene="comGF"
                     /locus_tag="ACHA1B_000888"
     CDS             16896..17321
                     /gene="comGF"
                     /locus_tag="ACHA1B_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGF"
                     /protein_id="HFM8701670.1"
                     /translation="MKKQVIPAFTLIECLIGLMILSSLLLTFNLLIQQTIQVSEFLQR
                     KDQKEWLIFLAQLEEELKSSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQ
                     PMLTSITELQLLEKEHTISFYVHFENGEDGYAIWTKNDQ"
     gene            17293..17652
                     /gene="comGG"
                     /locus_tag="ACHA1B_000889"
     CDS             17293..17652
                     /gene="comGG"
                     /locus_tag="ACHA1B_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence type IV pilus minor pilin ComGG"
                     /protein_id="HFM8701671.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17824..18831
                     /locus_tag="ACHA1B_000890"
     CDS             17824..18831
                     /locus_tag="ACHA1B_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM8701672.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            18856..20040
                     /locus_tag="ACHA1B_000891"
     CDS             18856..20040
                     /locus_tag="ACHA1B_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate/propionate family kinase"
                     /protein_id="HFM8701673.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20477..22060)
                     /gene="abc-f"
                     /locus_tag="ACHA1B_000892"
     CDS             complement(20477..22060)
                     /gene="abc-f"
                     /locus_tag="ACHA1B_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="HFM8701674.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22165..22293)
                     /locus_tag="ACHA1B_000893"
     CDS             complement(22165..22293)
                     /locus_tag="ACHA1B_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701675.1"
                     /translation="MMRMTKITSNENYQRYHIAFSHAIGFTVAVDGTSLSKTVEFT"
     gene            complement(22638..22781)
                     /locus_tag="ACHA1B_000894"
     CDS             complement(22638..22781)
                     /locus_tag="ACHA1B_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HFM8701676.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23004..23483)
                     /locus_tag="ACHA1B_000895"
     CDS             complement(23004..23483)
                     /locus_tag="ACHA1B_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFM8701677.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23556..23840)
                     /locus_tag="ACHA1B_000896"
     CDS             complement(23556..23840)
                     /locus_tag="ACHA1B_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701678.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(23918..24112)
                     /gene="ssrS"
                     /locus_tag="ACHA1B_000897"
     ncRNA           complement(23918..24112)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ACHA1B_000897"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24184..25470)
                     /locus_tag="ACHA1B_000898"
     CDS             complement(24184..25470)
                     /locus_tag="ACHA1B_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HFM8701679.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25608..26279
                     /locus_tag="ACHA1B_000899"
     CDS             25608..26279
                     /locus_tag="ACHA1B_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HFM8701680.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26245..26733
                     /locus_tag="ACHA1B_000900"
     CDS             26245..26733
                     /locus_tag="ACHA1B_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HFM8701681.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26746..27693
                     /gene="prmA"
                     /locus_tag="ACHA1B_000901"
     CDS             26746..27693
                     /gene="prmA"
                     /locus_tag="ACHA1B_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HFM8701682.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27694..28458
                     /locus_tag="ACHA1B_000902"
     CDS             27694..28458
                     /locus_tag="ACHA1B_000902"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HFM8701683.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28691..30904
                     /locus_tag="ACHA1B_000903"
     CDS             28691..30904
                     /locus_tag="ACHA1B_000903"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HFM8701684.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            30915..31361
                     /gene="dtd"
                     /locus_tag="ACHA1B_000904"
     CDS             30915..31361
                     /gene="dtd"
                     /locus_tag="ACHA1B_000904"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HFM8701685.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31532..32791
                     /locus_tag="ACHA1B_000905"
     CDS             31532..32791
                     /locus_tag="ACHA1B_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004497 - monooxygenase activity [Evidence
                     IEA];
                     GO_function: GO:0005506 - iron ion binding [Evidence IEA];
                     GO_function: GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA];
                     GO_function: GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HFM8701686.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(32880..33827)
                     /locus_tag="ACHA1B_000906"
     CDS             complement(32880..33827)
                     /locus_tag="ACHA1B_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFM8701687.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34221..35513
                     /gene="hisS"
                     /locus_tag="ACHA1B_000907"
     CDS             34221..35513
                     /gene="hisS"
                     /locus_tag="ACHA1B_000907"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004821 - histidine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006427 - histidyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HFM8701688.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35528..37297
                     /gene="aspS"
                     /locus_tag="ACHA1B_000908"
     CDS             35528..37297
                     /gene="aspS"
                     /locus_tag="ACHA1B_000908"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA];
                     GO_process: GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HFM8701689.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37406..38281
                     /locus_tag="ACHA1B_000909"
     CDS             37406..38281
                     /locus_tag="ACHA1B_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFM8701690.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38547..40430
                     /locus_tag="ACHA1B_000910"
     CDS             38547..40430
                     /locus_tag="ACHA1B_000910"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HFM8701691.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40505..40789)
                     /locus_tag="ACHA1B_000911"
     CDS             complement(40505..40789)
                     /locus_tag="ACHA1B_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFM8701692.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40779..41513)
                     /locus_tag="ACHA1B_000912"
     CDS             complement(40779..41513)
                     /locus_tag="ACHA1B_000912"
                     /EC_number="2.1.1.223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016430 - tRNA
                     (adenine-N6)-methyltransferase activity [Evidence IEA];
                     GO_function: GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HFM8701693.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41642..42265
                     /locus_tag="ACHA1B_000913"
     CDS             41642..42265
                     /locus_tag="ACHA1B_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="HFM8701694.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42457..43578
                     /locus_tag="ACHA1B_000914"
     CDS             42457..43578
                     /locus_tag="ACHA1B_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HFM8701695.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43585..46713
                     /locus_tag="ACHA1B_000915"
     CDS             43585..46713
                     /locus_tag="ACHA1B_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM8701696.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46732..49926
                     /locus_tag="ACHA1B_000916"
     CDS             46732..49926
                     /locus_tag="ACHA1B_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HFM8701697.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50072..50779)
                     /locus_tag="ACHA1B_000917"
     CDS             complement(50072..50779)
                     /locus_tag="ACHA1B_000917"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM8701698.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51544..51942
                     /gene="spxA"
                     /locus_tag="ACHA1B_000918"
     CDS             51544..51942
                     /gene="spxA"
                     /locus_tag="ACHA1B_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SpxA"
                     /protein_id="HFM8701699.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52274..52927
                     /locus_tag="ACHA1B_000919"
     CDS             52274..52927
                     /locus_tag="ACHA1B_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HFM8701700.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53153..54151
                     /locus_tag="ACHA1B_000920"
     CDS             53153..54151
                     /locus_tag="ACHA1B_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA family protein"
                     /protein_id="HFM8701701.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54327..56135
                     /gene="pepF"
                     /locus_tag="ACHA1B_000921"
     CDS             54327..56135
                     /gene="pepF"
                     /locus_tag="ACHA1B_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HFM8701702.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18496 a         9711 c        11662 g        16346 t
ORIGIN      
        1 tttataaatc aaaaatacag agaatagtat ataaatgtcc tttcctattc ttaaaatgat
       61 gtttgtactt acttaaatta ggtataatta gtatatgttt tgtgagaaat ttagacttac
      121 aataagcagt gaatttataa tcaacgtata ggagacatgg atgaaatgaa actaattggt
      181 atagatttag acggtactct tttgaattct gaccagagca ttagtcaaaa aaatgcaaga
      241 acaatgaaac atttaccgga agactgtttt ccattcattt gttctggaag agaagtagaa
      301 gacattaata atattctcaa aaaatctggt ttaaggatac cagcagtagg gttaaatggt
      361 tctgttggat ttgatggaga aaaaaagata tttgagtctt ccttcgataa aaatgatgta
      421 aaaaaaattg attctgtcct atcgaaattt ccaaccaaaa tatatacaaa tctcggaagt
      481 tatgaatctc agaattataa aaataaaatg aaaaaaattt ttcacgaggt agggagtgaa
      541 ttttctatca aagagctaaa ctatgagctt gagtatgaaa aatctatttg ttcaatccct
      601 tataataata ttgaggaaat tatagaaaag gatgctatca gcatttacaa attttttatt
      661 tttattccta atcgtcaatt gaaagctaat atatttaacc atttgaaaaa gatgctaaat
      721 gtgtctgtta ctgaatcggc acctgtaaat attgaaatcg tacctcaaaa tgtatctaaa
      781 ggtgtggtgt ttgatcgttt ggaatcaatc tacaatttaa agaaaccttt gagaatcgcg
      841 atcggagata gtttaaatga cttatctatg tttgaaagtg cagatattag ttttgcaatg
      901 ggaaatagtc atcaagaaat catgaaaaaa gctgattatg tcactgtttc aaatgataaa
      961 gacggagtat ctcaagcatt tgaaagaatt cttaccatat aaactaatta aggtagtata
     1021 gaacatagaa ttctaaatac ggaaaaatgg agcataaatt ccagtacaaa tagtacttct
     1081 tcagtgtcaa acgaagcgaa tataacatag atatttagga ttgtgacaaa aatcatgtca
     1141 caatcttttt ttcgaataaa cttatttttt gaagtcggcc atttatcgta atttctttgc
     1201 ataatacgaa caaattttcg gttattgatg aaaaaaaaca ttgaaaatgg tatgataaaa
     1261 gaaaaaaagg aggaaatttt taatggtgaa atttatccat gcggcagatt tacatatgga
     1321 tcggtcattt gaaggactga caactcttga taaaactgta caggaaaaac tattgaagac
     1381 gaatctgacc gttttatcaa atatcattga acaggcaata ataaataacg ttgattttgt
     1441 tttacttgca ggagataatt ttcatcaaaa tcgtccttca ttaaaaatac agaaacattt
     1501 ttcagaacag atgaaacggt tagaaaagaa ccatatacct gtatttataa tattcggaaa
     1561 tcatgatttc tatcaaaaag agcggtattg gttctccttt cctaaaaatg tccatttatt
     1621 tacatccgaa acggtagaga caaaaaaaat aacgataaaa agtggagaaa ctgtctctct
     1681 cagtggattt agttatcgtc aaccgtggat tcaaaaagac aaagtgatgg aatttccttc
     1741 tagagaactc acagattacc atattgggtt gtaccacggg gaacctggcg tctctcaaaa
     1801 aggaaactat gctcctttcc aaccctcaaa gatgcaagaa aagggatacg attattgggc
     1861 tttagggcat atccatgtgc caacggtctt aaatgaaaag caaacaattg tttatccagg
     1921 tgcgcctcaa ggtcatacta aaaaggaaca agcttctaca tctattctac tagttgaatt
     1981 aagtaaagga agttgccaaa tacatccgat taaagtagca gaggtctatt ggaagacaaa
     2041 ggaaatatca ttgaggaaag caagaacgac aaaagaggtc attgttcaca ttcgtcagca
     2101 gctttcaaaa gtagaggatg gatttagttt aattgagata aaattaaaag attatgacca
     2161 tctcaataca gatgttttgg aacggataca atcaggagag ctattagact atttgttaga
     2221 ggaattctca gataggataa atgatttctt tatttggcgt atttctctca tagagaatac
     2281 tttttatacg aagaccccac ttgctgcttc tgctaaattg atggaacagt tatttcaata
     2341 ctatcagaca cctcaagatt tccaacaaat tttaaatgaa gtatatagtc atcaagaagc
     2401 ggctagaata ttgagcgaac tgccggaata tcaagaagaa acacttgaaa aagccaagca
     2461 gctgcttaat caagattttt tatttgagga ggatcaggaa tgaagatttt aaggatcgag
     2521 attgctgctt ttggaaaatg gcgtcaaaaa agttttgact tttattcagg caatcagctg
     2581 atctatgggg gaaacgaagc aggaaaatca acgatttatc aatttattca agcaatatta
     2641 tttggtttcc cttcaaaagg ccgtaaaaaa aaggattata caccaaaaga cggctcagcc
     2701 tatggcggca aaatatggct taaacatcct gtatatggtg aatttgctgt cgagcgctac
     2761 aagcagcaaa atcgcggaaa atcgaaggtg tggctggggg atcaagtggg aagtgatgag
     2821 ttactagaaa aactgatcgc acctttgacg aaagagttat tccagcaggt atttactttc
     2881 cagcaagagc agttgatgga actagatcat ttgagagaaa aagagctaca tgatgcgctg
     2941 atttctttag gcatcacggg cagttctcaa gtattccaaa agcggcaaga atattatcag
     3001 aaagcacaac aattattcaa gaaaaaaggc caaaaattac taatcaatca aaaattaaat
     3061 gaatggaaag agctgcaaga aaaaattcat caaaaacaag aacaggaagc ttattttggc
     3121 aagttgatcc aacaagaaca ggaatacgag tcgcaacagc agcagttatt ggcacaatta
     3181 aaagaggcga acaaacaatt ttcattagcc agacagcaag aacttaattt ttctttatat
     3241 gaagaatggc aatctctcaa aaaaaacagc actacaggtc ttcctgatga gcaacttctt
     3301 ttagatctgg agtctttctc caaacggtat cagcaaacaa atgagcgttt ggaagaatta
     3361 gaagcaacac tggaaaagca tagcgggatg gatcagcagt cagccagata ttatttttat
     3421 ttagagcagg agcaggaact aaaagatctc cagcaacttc aatttacagc ggaacaatta
     3481 aacgaagaat ggcaaagatt acaaattgag actagagaaa caaattcaga attgaagatt
     3541 ttggaacaaa ggtggcattg gcagaaaaat ccgttaccgg aagaattttt atatgaagaa
     3601 gaatggaagc atcttctggc tgaagaaaga aggattgctg atctagaaag ccagatttct
     3661 gtgcgtctcc aaatagctaa agaacagcaa gagatgattg aagcagaagt gaatgacttg
     3721 gaagagacct atccagcatt attacaaaat cagtcagaga tagcaccagt ctcttcatct
     3781 aaaccgtata tgctgatggc tggcggagca ataatcattg caggtatatt tgtaccaatg
     3841 cccttgaaag tgatcctttt actaattggt gcaggcatga ttggctattt cttctacaaa
     3901 aggcaaccaa aaattaaaac taaaaatgat ttctctgaga taaaaggaat gtggcaagaa
     3961 aaactaggac aacttgatct agccttagct caattagctg aagcagaaga aaaacaaaag
     4021 agaactggag aagaaaaaca gattcttcag caagaagtat atcgttttgc ggatcatcgg
     4081 cacttaggaa agatggatac gctcaaactc atgaaagaat atggacagga agtcatagat
     4141 tatcagaaat tatatggcgt atttgagcgg aaacataaaa gagaacagga aatacaagaa
     4201 aaactacgac aaatcgacca aaaatttgag tttgttaaag aatggttacc gatacaagat
     4261 aagacaattt cagaaaaaat ggtattgctt tcccgtttta tacaagagat ggaacagatg
     4321 aaatttgcca gaagctatca gcaaaatact ttattgaagc aagaaatcaa tcaattgaaa
     4381 aagaaacaaa aagtatggat acaagaatac agcgaacaat tgactcaagc aggcttatct
     4441 tatccttcgg aagtacctgt ctttttacaa aaagccaaac aagccgaaca gcagatgaaa
     4501 agatacaatg aattatcgga aatgcttact ccactatttc ctgaagagct gacaaaagag
     4561 aaattatctg taagactgcg ccaactgaaa gaaaagcaat cccaactcca gcaagaagaa
     4621 aaagaagcaa gtgaaaatcg gcaacgactc caacttcaag tagaagagtt gcaaagagac
     4681 ggcacattgg acgaacttta tcaacaagct agccggcaaa aagcaaaatt acaggaatta
     4741 ctggaggaat ggggagcact tgaaatcgcc gggacattct taggtgatct ttcaacagag
     4801 atgagtgaaa gacaattacc ccagttgtta agagcagcag gtgattattt aggtatttta
     4861 acaaaaggaa attatcagaa gatattactg aaaaatgata cactgacttt aacagacgga
     4921 tatacagaat ttcccatcta tgagttatct acaggtacga aagatcagct gattatggcg
     4981 atgagatttg cttacctctc attagaagct aaccgttcga tatgcccgat catcattgat
     5041 gatggctggc ttcattatga tcatcagcga aagtatcaat tagctgaact tttagctaaa
     5101 tttggagaaa agtatcaaat aatttgtttt tcttctgata aagaaatggt aagctattac
     5161 catgagatga accaaatcgt aaaacaatta gaaggagcaa ataatgaaaa aaattcgtga
     5221 tttagtaatc gatgagcagt ttgaacaatt tgtcctgatc aaaagtgcag atgtaagaat
     5281 cgctaaaaac ggaaaaaaat ttattgcttt tactttccaa gatacttcag gtactatcga
     5341 tggtaaatac tgggatgctt cggaggagga aatcaataaa tttacagccg gcacagtcgt
     5401 ttttctaaac ggtaaaagag aggtttatca aggaaaccct caagtaaaga ttcttcatat
     5461 gcgcttaaca agggtagatg agccaggaga gcctagttta tacatggaaa gagccccttt
     5521 gaagaaagaa gaaatggaag aagaaatcaa tcaattgttg tttgagatca ccaatgcgca
     5581 ttggaatcgt attgttcgct atctacttaa taaatatcaa aaacaatttt ttgagtttcc
     5641 ggcagcaaaa agaaaccatc atgcatttgc cagtggatta gcttatcata ctttgacaat
     5701 gcttcactta gggaaatcaa tcgccgatga atatcctgag ctgaatcgag cattgttgta
     5761 tgctggtatc attttgcatg atttaggaaa ggtgattgaa ctttccggtc ctatgtcgac
     5821 agaatatacg cttgcaggaa atttgatcgg tcatctggta ttgattgacg aagaaataac
     5881 taaagcctgt cttgcgttga aaatcagcga agctgacgaa gatgttctcg tattacgtca
     5941 tatggtttta gcacaccatg gcttattaga atatggctca cctgtacgtc caagaataat
     6001 ggaagcagaa atattacatc aaatcgacaa tatcgatgct tcgatgcaga tgatgttgac
     6061 ttcgattcgt caaacagaac caggaaaata caccgatcgg attttcggta tggacaaccg
     6121 aagtttctat gtaccaaaag atttatagca aaaatttatt tttttcattc aaaacaaaaa
     6181 aagcgagaca taagtcttcg ctttttttgt tttcttttat tttgatgaat cagttgtttc
     6241 ttcagttgaa gattcttttg ttgaatcagt tgattttgtg tcagaactct ttgttgaagc
     6301 tgtagtttca cttgagtctt tcgtacttga tgaagttgtt gtgaatgcac tcaacacatt
     6361 ttcaaaggca tcatctttga tttttacatt tgcatctttt aattcttcac cgattacttt
     6421 agttgtgaat gcattgtcac ttagtttagt ttcagtagcg atatctttta gttgatcttt
     6481 gtatttatcc atgtcattgc ctttattttg gtttttcacc attttgacaa cgtagtattc
     6541 tgtcgcataa gaagtaggat ttgttgtagt aataacatcg gagatctcac cgtctttcaa
     6601 tttgaaagct gcttctttta cttctgcagg aatagttgtt gtcgttgagt cgaatttaac
     6661 tttaccgcca tcttcttttg tctctgtatc agttgatttg tctttggcta atttagagaa
     6721 atcatctcca tcatccgctg attttttcac atcttttgct tcatcttcac ttgataattt
     6781 gatgatttgt gcttctactt ctggatggaa agatttccaa gcagttttca aatcgtcatc
     6841 tgtaatatct acgtgagctt tcaagccagc ttcaaaagct aaattgttac gaatatattc
     6901 tttataagta tctttcgtat atccagcagc ttctaattgt gattcaaaag tatcacctaa
     6961 tgatttcgct tgtttgtcgt attctgcatc cacttgctta tcggttactt tatcgccata
     7021 tttgttattg aatactttat aaatgatcat ccgttgtact aaggattggt tcgatgattc
     7081 aagttttgct tcatcataga aatcagatac agtgatcgtt ccgcctttca tcgttgcgat
     7141 atctttatta gtatcgcctg aacaagctgc tagagttaaa acagccaacg cactagtagc
     7201 tgccaaaata attgattttt ttttcattaa aatttgcact cctgtaatta gttattattt
     7261 ttatatatta actataccat atcccatttc ctttaaaaac gttgtcgtgg tagtttcaaa
     7321 caaaattcaa aatttcatca cattcctagg aaatacgcaa acttttctca cttatatagt
     7381 taaatctgtt gagaaaataa tcattattat atttgttcag gatactctgg cagatcagct
     7441 tttagttttt ctacttgttc attgatttgt gtgatacgtg gttcggcttg gaatttaaaa
     7501 tcttcgatat cttttttgat tgcttcttgg aaagcaggaa tcacagattc agctgtttct
     7561 tttgtttcga tcaatgcgct tttaaaatga ttcaggctgt tatttaaatc atttgtcaga
     7621 gttgttgctt cttccaattc ttcgatcagt ttctttcttg tttcattccc gctcctgggc
     7681 gccaataaca gacctccgac agtgccagca gcagctccaa ataacagtcc tttgaaaaag
     7741 tttttaatca tcgcaggaca cctgctttac gattgtttct tgaatagctt ttagttcttc
     7801 cgatccataa ctatcttgat gattgacaaa gtgaatagaa aaatcatcct ctttgctgta
     7861 gcgagggact aaatggatat gtgaatgaaa aacagattga taggctagtt cacggttgtt
     7921 attcaagata ttaagacctt tcatttctgg aaaagctttt tccaatgctt gagcaatctt
     7981 aggcacacgc gaaaaaacct ctcctgcaag ttcgggatca tattcaaaaa tatctgctac
     8041 atgacgttta ggcacaacta atgtgtgtcc tttcgttgct tgagagatgt ctaaaaaagc
     8101 atagaccttg tcgtcttcat atattttata gcttgggatt tcttgattga tgattttgca
     8161 aaaaatacag ttttccatat aaaacatcct ttctataaag aataaatact tcagcttaac
     8221 tttaccataa gttaaagcta ttgtaaggaa aaaaacaaaa taccgtcatt ttcttcgtgg
     8281 tataataaat aaaaataaat ggcggaggaa aaagaatgag tttaattatc gatcatgtca
     8341 caggggggta cggacatctc cctgtgttaa aagatatcag tttcgatgta cagcctggag
     8401 agatagtagg gttgattgga ctgaacggag cagggaaaag tacgaccatc aagcacatta
     8461 tcggtctgct ggaagcttca aaaggaacga tagaaatcaa tcatctatcc ttaaagaaaa
     8521 atacggaaga atatcgcaaa caaattgggt atattccaga gactccttct ttatatgaag
     8581 aattgacatt gagagaacat atcgaagtca ctgcgatggc ctacgatata cctatggata
     8641 tagcaatgaa aagagcagaa aagttgttgg agacttttcg gttatctaat cgtcttgact
     8701 ggttcccagc taatttttca aagggaatga aacagaaagt gatgatctta tgcgcctttt
     8761 tgatcgagcc ttctttatat atcatcgacg aaccattttt aggcttggat ccactagcta
     8821 tcaatgcatt gcttgaattg atggtagaaa tgaaaaaaga aggagccggt attttgatgt
     8881 ctacgcatat tttagctact gcagaaaaat attgtgatcg ttttgtggtc ttacataacg
     8941 gagagatacg agcagacggt tctcttgaga tgttgagaaa agaatttcag ctgccggatt
     9001 cttctttgga cgaaatctat attgctttaa caaaggagca ggcacatgag tagttttttt
     9061 caaaaacgtt tagcaagaca tcaaaagaaa atgatgaaat atatgcgtta tgtattgaac
     9121 gatcattttg ttttagtttg tcttttcttg attggcggtg tgggattata ttattctaat
     9181 tggttgaaaa ccctgcagcc accgtttgca attggagggc tcataatctc tgtattttgg
     9241 atgctctgtt tattcgtggg taagatggct acttttgcag aggcagcaga tattgttttt
     9301 ttacttccta aagaaaaaga aatgcaaacc tatttggaac gagcttttcg ctattcttgc
     9361 atttttccgt tgatcttttt gatattggca tgcggattgg ccatgccatt agtggtggtt
     9421 agtacggagc aatccttttc gatgtttttc gtctatctga tcatattatg gagtttgaaa
     9481 ttcagtcatc tgcaaatcaa gagagcagaa ttgtttcgac tagatcaaca agttattcgt
     9541 tattggaaat taggctggtt tttttcttct ctgatctttt tgtttctatc attttattgg
     9601 ctaatatggg caggaatagc aggtgcatta gtacaggcaa gtctatatta ctggtttttg
     9661 tggaagcaac aagaaaaagg attggattgg gagaaaatgg tgcatgtaga agaacatagg
     9721 ttgcatcaga tctatcaatt tatcaattta ttcacagatg ttcctgaaat tacggcaaag
     9781 atcaaaagaa gacgctattt ggatcctata ttgactcata ttaaaagaga atcaaaaaac
     9841 acttatcttt acttgtttgc aagaagattg gcaagaggtt ctgattttag tggtctttat
     9901 ttccgattag taattatagg tgggttattg attgccggag tagtcgactt ttattttagt
     9961 ctgattatcg gtttcttatt tttatatttg atcggtttcc aactgttacc tttagcgaac
    10021 cagttccgct atatggttct cgttcagctt tatccaatcc ataagaatca gaagaagcag
    10081 gcgattcagt atctactcac atgggtatta attatcgcgt cggttatttt tggtttgatt
    10141 gctgcagtcg tattagatgg gcagcagcga tgggttccgc tagcggctta tttgattgtt
    10201 actatgctct ttgttaaact atatgtacca actcgtttga agaagatgtc agactgaaaa
    10261 caaagctgtg tagggtaaaa atgagaatga aaaatagagc gttgacagta agaatgctgt
    10321 tcgttctatt ttttttgaga aaagctggtt ttttgaatgg caattaaatg aaaaagaacg
    10381 tatatgtgct tgacgtgtag tgttcaggcg actagaataa taagtactgc aaaacaaaga
    10441 gtaagaggac gggagaatgc atgatggagt ttcagttaga ccaagagtgg cggttacgtc
    10501 ccatcaaagg cgacacagga aaaacataca taggcatgcg tgatgaggac aaagtcttta
    10561 ttaaacgaaa cacgactccg atgttggctg ctctttcaag ggaaggaatt acaccaaaac
    10621 ttgtttggac aaaacgaacg gggaatggcg atactttgac agcacaagag tggctggaag
    10681 gtcgcttgct gactcctaat gagattggtc aaagaaacga cgtgattgat gttttgtacc
    10741 atttacatca ttcaaattct cttaaaacca tgctgacccg tatcggtggt cgtgtcatga
    10801 cgccggagaa gatgctgcaa aaatatgaaa aagaattacc ggaagaactc cagaaaaatc
    10861 aatttctgca aattgtccat cgttttcttc gtgagcagat cccgtcaata gataaggaaa
    10921 acttatcagt agtacacgga gatgtaaacc atcgtaattg gttagtatgt aaaaattatt
    10981 tatatctagt cgattgggat tcaatcatgt ttgcagaccc tgcggtggat attgcaacga
    11041 ttttaggaaa ttatgtgcca ctgtctagct ggaatcagtg gctgatcagt tatggcatac
    11101 gcccgactga cgaaatgctt gaaaaatttc attggtatgc ggccatgaat ttgctccaag
    11161 aaatcaccag atattgcaaa cgtgaagatc atcgacggat gaacgaagaa attttacaat
    11221 taaaacgaat tttcagtggc tgaggtttgg cccaaactct gcggagattt ggccagacct
    11281 ttttaattag aggaaaggaa tggagataaa taatgcgtgt ccgaaatcgt ccgggagcag
    11341 cggaaatgtt agcggctcac ccgaattttg taattagtga tccaacattg tggaagggaa
    11401 aatggaatga attgtttgaa aacgatcatc caatccacat tgagattggt atggggaaag
    11461 gccagttcat cactggaatg gcaaaagccc atcctgaaat caattatatt ggagtagaaa
    11521 tgcaggtcag tgttgtttcg attgcactag acaagttgat cgaacaaccg cttcctaacc
    11581 tgaaacttct acatgtggat ggatcagcgt tgacagagta tttcgctgac agcgaagtag
    11641 atcaaatcta tctgaatttt tccgatccat ggccaaaaaa acgtcatgaa aaacggcgat
    11701 tgacatataa gacttttctt gctgtagatg aacagattct tcgtccaaat ggagaaatcc
    11761 atttcaaaac agataatcaa ggattgtttg agtattctct ggcaagtttt tctcaatatg
    11821 gcatgatcct caaacaggta tggttagatt tacatcaaag tcaatttgaa ggcaatatta
    11881 tgacggagta tgaagaaaaa ttttcttcaa aaggtcaacg tatttatcga gtagaagctc
    11941 aatttcaaga taagaccaaa aagaaaagtc tgtgaaacta actttctgct ttcataaaaa
    12001 cattaatatc cataaataaa tcccagaaaa tgaacattac agatgtaatg tattttctgg
    12061 gatttatttg atttaaaatg tatttatttc atcggttttt ccacaaggtg gaatcaattg
    12121 gaagcgagaa aatgaaaata atcctttgtc ggtgatcttc aattcgggta tgacagataa
    12181 tgttaagaaa gaaagtgtca aaaaaggatc aaaggtttta gctgctccta gttgatgtgc
    12241 tttagttatt aattcattca actgttcata gacgatcgaa aaaggttcct gtgtcatgat
    12301 tccgcctata ggaagagaaa cacaagctat ttcctgctgt ttgttgacaa cggtcatccc
    12361 gccacctttt tgaatcaaaa gattagcagc atacagcata tcctcgtcgt ttgtcccaac
    12421 gacaactaga ttatgcgagt catgggcaat cgttgtcgct atcgctcctt gtttcagctg
    12481 aaatcctttc actatgccta atccaatgtt tcccgtttga tggtgacgct cgatcaccgc
    12541 aatctttaat tggtcttttt cgattgaagg aatgaatcgt tcgccttgtc ggtccacttt
    12601 ttctaccaaa tctttagtca ctagactatt cgggataatt tcgatcacat gggcttgtga
    12661 agaagaaaga agcagctcta acgaatgtgg atttaatggt tgagcgttta gttttggcag
    12721 acaacacgta tatgaatttg aatgatcagc aaataaatgg tcttggagtt gcccagattg
    12781 aacaactaat gttcccttat agaaaacttc atgaattggc agcttggtaa gatcgtctgt
    12841 taagaagaaa tcagcttgat acccaggggc aatcgcacct agtgttttca aatcaaaaca
    12901 ttctgctgca ttcaatgttg ccatctgaat ggcttgtaat ggatcgattc caagtgcaat
    12961 agcttgacgg acgatatgat cgattgatcc ttcttttact aaatcattga tcagtttatc
    13021 atcggtgaca aagaagcatc ttcttgaatt ttcaggtgtg atcgccggta gtagcgatgc
    13081 cagatctttt gcaacggtcc cttctcgaac cattaaatac ataccaagat ccaaacgttc
    13141 tttagcttct tttgcagttg tagcttcatg atccgtccga atacctgctg caggataaac
    13201 atttaactct tccatgccga taccagctgc atgcccgtca atttttttct tatgctggtg
    13261 catcaattgg atcttttcta ggatgtctgt ttcattattt gctactgctt gatagttcat
    13321 gacttcagct aagcctaaaa cttcgggttt ttgtaaaaaa ggggctaatt tttttgcatt
    13381 taaatttgca ccattggtct caaaaggggt tacaggtaca caagaaggta gcataaaaaa
    13441 gatattcatg agtgtttgtc ttgcatcttc tatcataaac tcaagacctg tactcccagc
    13501 aatgtttcct atttcatggg gatctgtcac tacagtagta actccatgaa gcaaggatac
    13561 ttttgaaaat tcgcttggtg ataaaagtga gctttcgata tgcacatggc catcgatgaa
    13621 tcctggcact agatattgcc cattagcatt atgtacgctt tttccttcgt attcaccgat
    13681 tcctacgatc attccttcgc agattgctac atctttttcc atgatttctt tcgtaaagac
    13741 gttgacgatc ttagcatgct tgatcactag gtcagcaggc ttttttttac ttgctacttc
    13801 gatatatttc cttaatgttg tttccaatgg agtgcctccc aagataaatt tttataagta
    13861 taacataaat tcggtttttg ccaatatttt tttgtaaatt cattttattt gaaacaaaaa
    13921 gatcaaaaag acgtatgttt tttgtggagg ggagaataat ggaaataaaa cgattatcgg
    13981 atcaaatgat aagtgaaagt tttgccaaac atgcccaaga cgtatatata ttgccagctt
    14041 cagaagtatt ttacatctat tttcgctatg gaaaaaaacg aacattctgg aagaaagtct
    14101 cttcggcaga tggacagcaa ctgatctcaa gatttaagta tttgggacag atggatatcg
    14161 gagaaaaaag aaaagctcag ttaggtgcat ttacttattc tttagaaaaa caggaagttc
    14221 gtctgcggtt gtcttctgta ggagattacc ttcaacgaga gagtttagtg attcggctat
    14281 tatacggtac ttttgaaaca ccccatcgtt gctttagttc tcgagatttt gcaactattt
    14341 tacagaaaac cgtcagacgt ggattatacc ttttcagcgg accagtcgga tcaggcaaga
    14401 cttctctaat gtatcggttg gctttggaag aaaaattgca agtgattact atcgaagatc
    14461 ctgtagagat agaagaaccg ttttttctgc agctacagat caatccgaaa atagcacaga
    14521 cttatgatac acttttgaga ctcgcattac ggcatcgtcc agacttgcta atcattggcg
    14581 agataagaga tgaatcaact gcacatgctg cggtaagagc agcactaaca gggcaccggg
    14641 tttttgcaac cgtacatgca cgcaatcttg aaggtacatt ggtcagaatc catgaactga
    14701 caaagaaaaa agaagagcta tctgaatgtt tagctggtgt catttatcaa gaacttttgg
    14761 aagatgccaa tcaccatcct tctgttttat ggagttatca atttatggag gaagaatcag
    14821 taaaaaaatc atgggaggaa agttatgaag aagctcagga aaatatttgg cagtcagaac
    14881 tattctaaag gattaacaag aagccagcaa aaccagtttg cacaaaccat gggagaactg
    14941 cttttatctg gttttagtct gcaagaatcc ctttatttat tactcacgat ccgttcgttt
    15001 ccacctgtta ttttggcaaa tatccaacat cagctaaagg aagggcaagc gtttagtgag
    15061 gtactttcgc aaataggata tggagcagag caactggtac agatcgagtt agctgaacgt
    15121 catgggaatc tgccgacaac tttgttggaa attgccaaac agtttcggct tgttgaagga
    15181 tttcgcaatg atttgaaaaa gctgcttgca tatccgatgc tattgctcac ctttttgcta
    15241 ggtatcttgt ttagtatgcg gttgttcgtt ttgcctcagc ttattggttc aggaatggtc
    15301 atgcaagagc attggggtat tcagctgata caagtctttc attggtatgt tctactattc
    15361 atcctagcgg ttactctatt ggctttacta gtaaggtatc gtctgatgaa gttgtctcct
    15421 gttgatcaga gtgaatggat aagcagacaa ttattgattg gaccgatata ttccttgtat
    15481 caatcggctt atttgtcact agagattgga aagctttttc atgaaggttt cgaattaagg
    15541 caaatcatag tctgcttaaa ggaaacgaaa caagaaagtc tgattcagca tcttgcctct
    15601 aagttgattc aaggattgga ggcaggtatg tcattggctg agcagttcca gaattatcgt
    15661 tttctatcag aagaattcag taaaattgtt ttacagggag aggcaaaggg aagtttaggt
    15721 aaagaactga ttttttacag cgaatggaca agaaaacagc ttttcaaacg tcttcatcac
    15781 tggatgcatt ttattcagcc aatcattttt ttgggcgtag cggctttgat tttattagtt
    15841 tatgccgctg ttttattacc tgtttacgga agcatagagg aggttttgcc atgaaaaaga
    15901 gaaaaatatc ttattatagc ggttttacat tgatcgaaat gctaatcgtc ttactgatca
    15961 tcagtgtatt agtgttgttg ttcgtcccta atttgtcgcg ttataggaat catgtagacc
    16021 aagaaagtcg tgaagcgatc atccagttgg tagacacaca aaaagagctc tatgcgcttc
    16081 aaaataatgg aagagttcct actgtggagg aattgttgaa tgaaggctat atcaaacgag
    16141 aacatgcaga aatctatcag cggccttgaa ggtaaggttt tagcatcagg atatacgttg
    16201 tttgaatcac tcttactgat tttattactt acaacgatcc tttcttttcc agttctcgca
    16261 ttttctgcat ggaagaatga attggcagtc tatcaatttt tcggccaatt tgaaaaacga
    16321 atctattcta cgcaaaaaat cgctattgtg aatcagatcc aaacaggctt ttattggaat
    16381 agtgaagaga atcaaatcat ttttcatgtt ccgaatccag ataaaataaa ttgggaagta
    16441 ttagatattc ctgatgagat taccttgaaa cgccatgctt ctattacttt tgctgctaga
    16501 accgggaatg aaagttcact aaaagcttat caattttatt gggaagaaaa agagcggacg
    16561 attacgtatc aattccagat agggagtggt cgctatacaa aaagaattga ataaaacagg
    16621 atttgttttg ttggagtccc ttacagcgct tatgatcgct tctgtctgtg tctacttagt
    16681 gagctttggc cagctgtttt tgcttcaggc agaaaagaaa agtggggagg aactgctatt
    16741 tattcgaatg atttatgaag atatcaagac gcagcggatg tatcacaaaa gaccagagcg
    16801 aagggaagaa atgatcccat acgatatcca aattgtcgat aataatggag taatcgaaaa
    16861 agtgtttgtc aatatggaga aagaagcgat cagtattgaa aaaacaagta attccagcat
    16921 ttacgctgat tgaatgtcta attggactga tgatattgag cagtctattg ctcacattca
    16981 atcttttgat tcagcaaacc atccaagtaa gtgaattttt gcagcgtaaa gatcaaaaag
    17041 agtggctaat atttttagca caattagaag aagaactcaa gagcagtcac aatgtctctg
    17101 tgaaaaatca gcaactgcac tacacgatcg aggataaaca gtatatcatc gaaagatatc
    17161 aggcaatgat acgtaaaaga agaacttccg gcggacatca acctatgtta acaagtatca
    17221 ctgagcttca attattggaa aaagaacaca caatttcttt ttatgtacac tttgaaaatg
    17281 gagaagatgg atatgccata tggacaaaaa acgatcagta gaaaatgtta taagggctct
    17341 attttatttt ctgtcttgct tttatttctt ttatgtacgt ttttattgat ggcagcatta
    17401 gaaagctacc gtttgtcaat ggatcttaat atacgaatca aaaattatta tatagcaaaa
    17461 ataatgaagc agatggcttt atcggaacag tctacgcttg ccgaaagttc ggaaggagtt
    17521 ttttactaca caactggatc tgtaacatat cagtgggtac aacagtccct attcttagag
    17581 gtggaagtct caccgtttat ctttcggttc acagaagaag taaaaaatga tacagatact
    17641 agtacagaat gatggaatgt tcgtgaaaac gccctctttt ctgttataac actgttttta
    17701 ataaaaaaat gtttgccgtt tcacaaataa aaaacagtga aaacgattga aattttgtca
    17761 attgttcgat agaattaaac aggtgaaaaa attgttataa tatatctaga aatgaggtgc
    17821 accatgttac cagaaaaaat ggaacaaggg tttaatcaaa acctggaagc tattcagctt
    17881 ttacagaatg cattgggaac ttccttttta gaagcctatg tcgaaaatgc agaaaattta
    17941 atagatgatt atcaagtacg tgtggtggat ggagtgccga caaaagagac aacgcaacgg
    18001 atcacagctc tttatgaaga gttgaagaaa ctttctttcg agccagaaga atggcgcaga
    18061 ctgtctcaat tacttttatt gaagggcagc cagacagaac atttgcaggc gaaccatcaa
    18121 ctcactcctg atagtatcgg ttttttattt gtttttctta ttgaacaact atacacaaat
    18181 aaaaaagcac cggttaagat tctggatatt gcggcaggaa tgggcaactt gttattaaca
    18241 gttcttttaa acctatcgaa tgcggggtac caaacagaag gaattggtgt ggatattgat
    18301 gatacattgt tggctgtcgc agcttctaca agtgatttga cacaagcaaa tgttcaatac
    18361 tttcatcaag acgggttgca ggaattatta atagatcctg tcgattttgc aatcagcgat
    18421 ttgccaatcg gttattatcc gaatgacgaa aaagcaaaag agtttttaac aagtaccgaa
    18481 gaaggccata gttatgcaca tcatttattg ctagagcaat caatgaaata tgtgaagccg
    18541 gatggttttg gtttgttttt gatgccgagt ggatttttag aaacggatca aagtgaagaa
    18601 atcaaaaaat ggtttaaaga agaaggttat cttcaaggaa tgattcaatt gccagatgaa
    18661 ttgttccgta ataaacaatc gcaaaaaagt attttgatct tacagaaaaa aggaccacaa
    18721 gcacaacaag taaaagaagt cttgcttgtg aaacttgctt cattaaaaga accagagaag
    18781 gtgacggaat ttttcaacga gtttaaaaac tggaaatcat ctgctctgta atcattcaac
    18841 gagaaggaga gtcatatgtc taaaacaatt gcaatcaatg ctgggagttc aagtttgaaa
    18901 tggcaattat atcaaatgcc agaagaaacc gtagttgcga aagggatcgt cgaacgtatc
    18961 ggtttacaag attctatttt taccatcaag tacggcgata atcaaaaatt cgaacaaatc
    19021 atggatatcg aaaaccacga agtagcagta aaaatgctgt tagatcagtt gattgaactg
    19081 caaattttaa gctcttatga tgaaatcacc ggagtagggc accgtgttgt tcacggagga
    19141 gaaacttatg gggattcagt agtgatcgat gagaaagtaa tggaccgcat tgctgaatta
    19201 gcagaatttg ctcctttgca taatcctgca aacttaatgg ggatcaaagc gtttaaaaag
    19261 attttacctg acattttgag tgtggctgta ttcgatacat ctttccactc aacaatgcca
    19321 aagcaaaatt atttatatag cttaccggtg tcttattatg aagatttcaa agtaagaaaa
    19381 tatggcttcc atggcacaag tcatcgttat gtgtcggaac gtgcggcaaa attattgaac
    19441 aaaccgatcg aagaactaaa aatcatcact tgccacttag gaaatggtgt atcgatcaca
    19501 gcagtcgatg gaggtaaatc catggatact tctatgggat tcacaccatt agctggggtg
    19561 acaatgggta cacgttcagg tgatatcgat ccagctgttc tcccatattt aatggaaaaa
    19621 ttagagattg atattgatga aatgatcaat gttttgaaca agaaatctgg tctgctaggc
    19681 ctaacaggat tgtctagtga tatgcgtgat cttgaaaaga actatgaaaa agaacatatt
    19741 cgtttagctt atgacatttt cgtggaccgc atccgaaaat acatcggcgg ttatgtgaca
    19801 acgatgaatg gtgttgatgc aattgtcttt actgctggta tcggcgagaa tgacggacat
    19861 gtacgtagtg aaatcatcaa aggtatgtct tggtttggtt gtgaaatcga tccagcgttg
    19921 aatgaattgc gtggtgaaga agtagatatc tctacaaaag aatcaaaagt aagagtatta
    19981 gtgatcccaa cagatgagga actaatgatt gcccgtgatg tggagcgtct gcgcggctaa
    20041 gccaaagcat tcgttaggat aaaagatgaa acgcatgcaa gagggaattc ttgcatgtgt
    20101 tttttttgcg gagaagaccg caaaatggta atttaacttc aatttccctt cttttttaca
    20161 ggatcttctt agggaatttt gcttggaaaa gtggtcaaaa gggaaaagac tggcatttta
    20221 tttattgatt ttcaggaaaa tcccaatatt ttattttcat tcatctttat aagggacatt
    20281 acatatgtaa aaagaaaaaa catttttaga tcagcctcgt gggctgtcga ctttattctt
    20341 cgctttatgt ttagctagaa aaccgatccg aaacattcat tgatcgaata ataaaaactt
    20401 gattttccac ctgtactttg cctgaatcgt gaaagcacag gtatgaaaat caagtttttt
    20461 gttgcgaaaa aacgtcctag tcaatcagtt ggccgagcgg ctggcggctg atctgctcct
    20521 gatcaataac gagtgcttct tggaagtgtt gctgcaaaaa gtagcggtca tggctgactg
    20581 ctaggagcgt tccttgatag tcttgcagca tttcttcaat ttcttctcga gcatagctgt
    20641 cgaggtgatt ggttggttca tccaaaatca ggacgttgat tttttctaaa aagagtttca
    20701 gcaacgccaa acggattttt tcaccgccgg ataaatcttt gatccgttta cccacatcgc
    20761 tttgataaaa gccacttttg gctaattgcc gtcgagcgac ttcttcgttt ccagtcaatg
    20821 tgatggcgta agccagcaaa cggctatcgg gatcggcaaa ctgcagctgc tgcggcaaat
    20881 aaccgatttg caagctacta cctaatttga tggtgccacc gtaaggcttt tcctcaccga
    20941 gtaataattt gagtaaggtt gattttcctg caccattgtc gccgatgatg gctaaatgat
    21001 ctccacgata gactgcaaaa ctgctgtctt tgaatagtac ttgatcagcg tactgctggt
    21061 gcaagttttg aatgatgaaa acttctttgc cagattttcc accattagac aagctttgca
    21121 gccgattttt cgggggaggt ggcggtttga cgagtgtcag tttcgccagg cggcgttcca
    21181 gttctttggc ttttttgaag aaggactcat tgtctccttc atgtgcccac tgacgaaaac
    21241 gacgaatcat gactttcaac cgctggactt ctttttgctg cagttcgtaa ttttttgtca
    21301 gctcagccaa gcgagcttct ttcaagactc gaaaacggct gtagtttccg ggatactcaa
    21361 tcaatgcacc ttcttccagt tcccatgttt ttgtggtgac ttgatcgaga aattgccgat
    21421 catgagaaac gaccagaacc gatttttttg tattctgtaa atagttttcc aaccagcgaa
    21481 tactgttaag atctaaatga ttggtcggtt catcgagtaa aagtaaatcg gcatcggctg
    21541 ctaaaatttt ggctaaagcg actttaactc gttcgcctcc gctaagttct gttaaccgtg
    21601 cttcctgacg gtgtggaatc cctaagcctt gcaagatcgc tgcaatccgg tcttctaata
    21661 cgtaaccgcc tagttcttca aagcgatgct gcagctcacc gtaacgggcc agacacttct
    21721 ctaagtttgt atctggttct gtcatcaatg cttcgtagcg actcatttgc tgtttgaggt
    21781 cctgtatctc agcggcagaa tggagcaagt agtggttgac ggtcgcttcg gaaactgtaa
    21841 gttcttgttc gaccgtcccg atctttaagc cttttttgcg actgataaca ccgctgtcga
    21901 caccttctct gccggtcaag atttgtaaaa aggttgattt gccagttccg ttgataccga
    21961 ctaaggcaat tttttcacca gcttcaattt gacaggataa atcctcaaat aatggattcc
    22021 cgccgattgt ttttttaata gaaattgctt gtatgatcat gatctctctc cttgagacca
    22081 ctcaaaaagg ccatggttat ccatggcctg tgttatttaa actcagatta tcatgagaaa
    22141 aataccttga gatggccatt gattttacgt gaattcaact gttttggaca aacttgtccc
    22201 gtcaacagca actgtaaaac caattgcatg gctaaatgcg atatggtatc gttggtaatt
    22261 ttcattactt gttattttag tcatgcgcat catagtattt tccctccttc gtgtagttgt
    22321 cttttccagt gtacctgaaa gtgtcagaaa gttcaactag cgctgacatt tacttaatat
    22381 ttatcgatgt gtaattctgt cagagagctt tttttatctg actgagggta atgtctcgtg
    22441 gaccacatca ttgtattctg agctaaacca gcgttcaggc gaaatcatat ggtgtttgat
    22501 aaaaaacttt gtctacatga cttccttttg ccatttgctt aataccgttg cattaaacag
    22561 ctcttctctt tggaaatctc accaacatcg cgttcaggag tatcgttgtg gttgcaatgg
    22621 caagcggtag cctttcatca attcttgaat gatttaccga atgtagcact tgccttctcg
    22681 cggtacccga acccgaaata aaattttagt ttggcgataa aatcggtatc cgccatcgat
    22741 acttcatatt ttttcgtatc agattcatcg gaaacttcca cattgacgaa ccaataagct
    22801 ttggcatgct taggtcgttt taaaccacac cagggcgact aatcgccctg gtgttcactt
    22861 ttttttattt tacttgaact cattgactgt tttcccttta ttttaaacat tataaagacc
    22921 gatgagtgct tgccgcgtct tttgttttta tcacggtttt ttgtgcaaaa aaacctgccg
    22981 atagttggca ggtcgtctac gtgttaagct ttggtgtggt ctttagctgg caattggttt
    23041 tctaaatcag ttcggacaac aagcacatcg caagctgcgt ttctaataac atattcagaa
    23101 acagaaccaa taaataaacg ttctacagca ttcaatcctg tggctcctaa cataatcaaa
    23161 tctacttgat tatcttctgg gatttctctg gcaataattt gttttggtga gccatattct
    23221 acgacagagg ttacattatt caagccagct ttcttcgcat tgctttcata atctgccaat
    23281 gtttgctttg ccatttcagt agcttgttct gcaagcattc catcaaagga tgaaacggtt
    23341 tggaaagaac gtgtgtcaat gacatgtgct aatagaagtt ctccgttatt tcggatagct
    23401 acattgaccg cctttttaaa agctaattca gcttcatcag aaccatctac ggcaaccatg
    23461 atttttttgt attgttgtaa cataagcatt cactcctcaa gtcaatcgta ttgtactctt
    23521 ttattgtaga acactttagg gaaaaagaga attatttact gctttggttc agcaattttt
    23581 tttgcaaatc ggatactgaa ggtggcagaa acaataatta cgatcagtaa aaagaccaag
    23641 gcaataaagc gttgattgaa aaaagctgtt aaaataccca ttacgcctaa aacagcatat
    23701 gcagctccgt aaaattgtag gaatccttga tttttatcat ttttgttgat caatacaaaa
    23761 aagatatcct gtttattaaa taaataatag ctaacgaata ataatactaa agtggcgata
    23821 atcattaaaa tcctaatcat gaacaaatcc tccaaaataa gcaacaaata gaaaaagcaa
    23881 tttgccaaga gcaaattgct ttattcttta aaagatggta atctccgtta atgccgttgt
    23941 ttgtcctgta gtattgatcc cgcgaattca agcaggtggg tcccatggtc gtagcttcga
    24001 actaccaaat gataaggcat gttaccagca gtgacacaag acgggtccca agatatcaat
    24061 aaaaatgttc ggtcaacaca caaagaggac aattcgaaca tcacagattt cccacctcta
    24121 tagtagcata tgaatttaaa aagagcaatg agagagctcg cagaaacaga accgttttct
    24181 tgtctagttt tttggaggat gctttttcca ctcttttata cggtaatact gttgacccag
    24241 agcctgttca tatttccctg tatcttttgg ctgataatac tgagcattct tcagtttatc
    24301 tggtaaatat tgctgattga cccaagcctg atcaaaatga tgaggatact gataacccac
    24361 gccacggttg agtgatttcg cacctttgta atggctatct ctcaaatgat caggaacatc
    24421 tccagctttg ccctctcgaa tatcagcaag tgctgcatct aatgccatgt aggcagaatt
    24481 ggattttggc gacaagcaaa gatcgacgac gacgtctgct agtgggatac gtgcctcagg
    24541 caatcccaat ttttcagcag ctaatacagc gttcactgta cgagccgcag cagcaggatt
    24601 acctaaacct atatcttcat aaccgataac catcagacgc cggcaaatac ttgccagatc
    24661 acctgcctca actaaacggg cgagataatg aagtgcagca tccacatcac ttccacgaat
    24721 cgatttttga aaagccgaaa taacgtcata atgagcatct ccatttttgt catgggtaag
    24781 agcttttctt tggacacatt cttcaatgat cgacagtgta agatgaatcc ttccttcttt
    24841 atctgaagga gtcgatagtg tagccagttc cagcccattc aatgcactcc gcaaatcgcc
    24901 gttcgttgca cgcgaaaggt gaagaagagc atcttcgtct aactggattg cttgttgtcc
    24961 aaggccgcgt tctttatccc ttaaagcatg ttcgactgcc aactggatgt cttgttctgt
    25021 taatggtttg acttcaaaga tctgtgtacg gctgcggatc gctggattga tggtaatata
    25081 aggattctca gtagtcgctc cgatcaagat gattcggcca ctttctaaat gaggaagcag
    25141 aaaatcctgt tttgttttat ctaatcggtg tacttcatcc aataagagga tcactgtacc
    25201 actcattttt gcttcttccg ctacaacttg tagatccttt tttgaatctg tagcggcgtt
    25261 tagcatgcga aatgcataat tagtagagcc ggcgatcgca cttgcgatac tcgtttttcc
    25321 agtaccagga ggtccatata gaatcatgga agagagcatg cgagcatcga ccatgcggcg
    25381 tatgattttt ccttccccga ctagatgctg ctgaccaacg acttcatcga tcgttcgagg
    25441 tctcatgcga taagccaatg gctgttgcat aggattttcc tccttcttgt ttttacgtcc
    25501 cttaattata tcatatttag caagatgcct agaaagaaca gccttctgtt gttttgtttt
    25561 catagcttat ccaactaata ttgtgtatga taaagtaggt gagaaaaatg acggataaac
    25621 aaaagataga tgaatttttt tggaataaaa cgacgccaga agtggcacgg gatttattgg
    25681 ggatgtattt ggagcatgac acaccagaag gaagattagc tggatatatt gtagacgcgg
    25741 aagcatacct aggtccagaa gacgaggccg cccatagcta tggtttaaga agaacaccgc
    25801 gtgtgcgggc aatgtatgaa aaaccaggta cgatctacct ttacacgatg catactcatc
    25861 ggattttgaa catcattact cagccagaag ggattcctca aggagtaatg atacgtgcaa
    25921 tcgaacccgc cgcaatgatt gatcaaatga gtaaaaatcg tggcggaaaa actggtccag
    25981 atatcagcaa cggtccggga aaattagtgg aagcattagc aattcctcaa gaactttatg
    26041 gtcagtctat agcagatagt tcgttacgct tagtttttga gaaaaaaaag acaccaaaaa
    26101 agatcaatgc tttgcctaga atcggtatcc caaacaaagg tgtatggaca gaaaagccgt
    26161 tgcgttttgt tgtgtcggga aatccttata tctctttaca aagaaaaaac caaatcgaga
    26221 aagattgggg ttggaggaaa gaaaatgaaa aagaaggatc tattaacata tttagatgaa
    26281 ataattgaaa aacaagtgac agactatgat gtagctttag attgggatac aaaaaatcat
    26341 acgatcgaga tcgttgttcg cttgtttgca gaaaataaag cacaatttga gattgatgat
    26401 gcagaaggga tcgtttcgca agaaccaatt atcgaatttg aagacggcgt acttcttttt
    26461 aatcctcaga aatctgtttt tgatgaacgc aattatctag cagtaatccc ttatgaagga
    26521 aaaaaagggt tggcaaaatc agtagctgat tctttagtgg aatatctaaa tgaagtatta
    26581 gctcaagggc aaagcgattt gcttgatttt ttggatgaag acgatgacga agctgtattc
    26641 gagcttcact gggataatca gcaactagca gaattagtag aagtaaaaca gcaaaatgaa
    26701 gcagatactt atttaccgta cccaagttat taaggagtga cagatatgaa atggaatgaa
    26761 gtaaaagtag aaactgaaag tgaagcagtc gaagcagttg ctaatatttt gatggaggca
    26821 ggggcgagtg gtgtcgcgat tgaagattct ttagatgttg aacattttca gtcggatcaa
    26881 tatggtgaga ttttagataa aaatgatttt acatcgctga aagaaggcgc actagtcatg
    26941 gcttattttc cggaaacgac tttcttaccg gaaatcttgc cttttatcaa agatcgtatc
    27001 acacaattac ctgagtttgg tctagctatt ggaaaaaata aagtaacagt tagtgaagta
    27061 gaggaaagca actgggcaac agcctggaag aaatactatc atccggtgcg tattacgcga
    27121 atgctgacgg ttgcgccaag ctgggaaaac taccagacag aagatcctct agaaaaaatt
    27181 atcacactag atcctggtat ggcatttggc acaggcactc atcccacgac ttccttgaca
    27241 ttgacagcac tagaaacagt cttgcgtggt ggtgaaacat tgctagatgt gggaactggg
    27301 tcgggcgtgc taagtattgc agcaaaatat cttggtgcaa aagatgtcta tgcctttgat
    27361 ttagacgaag tagccgttcg ttcggcgaaa gaaaatatgg atatgaatga aatagccaaa
    27421 gatgtccatg tatcagctaa cgatcttttg acaggaatcg agattgaaag tgatgtaatc
    27481 gttgcgaaca ttttagcaga tatcatctta ttgatgatcc cagatgcttg gcgtttactg
    27541 aagcaaacag gcacgctgat cgtttcagga atcattgaag agaagaagca aatggttctg
    27601 gatgccatgt tagaacaagg gtttatcgtg gatcaaattt tccagcaaaa agactggtat
    27661 gcaattattt tgaaaaaacc agaggtggaa tagatgcagc ggtatttttt aaaagaatca
    27721 tatgaatcaa aagactattt tgttttagaa ggggaaaact atcaccacat tgtacgggtt
    27781 atgaggatgg aacccgagga tgaagttttt ttggcattca atgatcaaat agccattgtt
    27841 gcagaaatca cggagattac tgaagaggct gtttatctga aagaaattaa aaaagaagaa
    27901 aatcaaaagg aactgccaag ttcgattacc atagcgagtg gctatcctaa aggggaaaag
    27961 ctggattgga tcgttcagaa atccactgaa ttaggagcgc aagcttttct tggtttcccg
    28021 gcatcagcct ctgtcgttaa atgggatgca aaaaaacgta tgaaacgaca acaacggctt
    28081 gaaaagattg ctcaagaggc agcggaacaa tcccatcggc agatcgtgcc atcagtagag
    28141 ttattggaaa cgaaacaaga tttatttgag cggctagatg attatgacgt ggtcttggtt
    28201 gcttatgagg aatcagcaaa gcaaggcgaa aaatcaaatg cagccaaaat tcttagtgaa
    28261 acaaaaccag atagtcgaat cttagctgtc tttggaccag aaggtggatt atcccgcgat
    28321 gaagtcgatt attttgtaga acacaaaggg atactttgtg gattaggacc aagaatcctt
    28381 cgtacagaaa cagcacctct ttatttatta agtgctgcta gctatcaatg ggaattaatg
    28441 aatccttctt tcagctaacg ttcttcatta ataaaagagt atcgacagaa agaattgaaa
    28501 aaatagtcaa caatttgtat aatagaaaca attatttata caatggatac gaaaaatcgt
    28561 ttgaaaaagc ttttaaaaag cgaacatttc cgtaaaaaaa cgtataactg cacggatttt
    28621 gggacaatta tcaaacagat atttgtcccg attcccgttt taccgaaaaa agaaaggggg
    28681 atcgattcct gtgacaaaag aagaaatttt aacgggaccc ggtgtcataa agctcgttag
    28741 tcaatacatg ggtcccgaac atgtagcatt tgttgagaaa gcatgcgaat acgcgactgc
    28801 tgcacatgac ggacagttta gaaaatcagg cgaaccctac attattcatc ctatccaagt
    28861 cgcaggtata ttagcagatt taaaaatgga tccccataca gtggctacag gcttcttaca
    28921 tgatgttgtt gaagatacag aaatcacttt agaagatctg agagaagaat ttggcgatga
    28981 cgttgctatg ttagtggacg gcgtaaccaa attagggaaa ataaaatata aatcccacga
    29041 agagcagcta gcagaaaacc accgaaagat gctgctagca atggctcaag atttacgagt
    29101 tatcatggtc aaattagctg atagactaca taacatgcgt acgttgaagc acctgcgaga
    29161 agataagcaa agaaggatcg ctcaggaaac tttagaaatc tatgcgcctc ttgcacatcg
    29221 tctagggatc agccggatca aatgggaatt agaagataca gcacttcgtt atctaaatcc
    29281 aaaacagtat taccgtatcg tccacttgat gcagacgaag agagaagaac gtgaaaaata
    29341 cgtaagtggt actgttgaag atattcgaat agcgacagaa gagctgggga tttttgcaga
    29401 aatctatgga cggccaaaac acatttattc aatctatcgt aaaatgaaag atcagaaaaa
    29461 gcagttcaac gaaatttatg acttgctagc tattcgagtg atcgtagatt caatcaagga
    29521 ttgttatgct gtattaggag caatccacac aaaatggaaa ccaatgcccg gcagatttaa
    29581 ggattatatt gccatgccaa aagctaatat gtaccaatct ttgcatacta ccgtgatcgg
    29641 tccggcagga aatccggtag aaattcaaat ccgaacacag gaaatgcatg aaatcgctga
    29701 attcggggtt gctgcacact gggcctataa agaaggaaaa aatgaaaaag tagaaccaga
    29761 tggtatgacg aaacaattaa gctggttcca tgagatactc gaacttcaag acgaaagcta
    29821 tgatgcttct gaatttatgg aaggcgtaaa aggagatatc tttagtgata aagtctacgt
    29881 cttcacacca aaaggagacg ttactgagtt accaaaagga tccggaccat tggactttgc
    29941 atacagtatc catacagata tcggtaacaa aaccactggt gcaaaagtaa atggcaaaat
    30001 ggtgcagctt gattacaaat tgaaaaacgg agatatcatt gagatcatga cttctccaaa
    30061 ttcatttggc ccaagtcgcg actggttgaa attagttgct actagcaaag caagaaataa
    30121 gatcaaacgt ttcttcaaag cccaagatcg agaagaaaat gtgatcaaag gccacgaatc
    30181 cgtggtcaaa tgtattacag atctaggatt tacgcctaaa gatattttga cgaagaacaa
    30241 actgcaagaa gcactcgatc gttttaatta tcaaacagaa gatgatctct atgcagctgt
    30301 agggtatgga gaagttagcc ccttgacgat ggccaatcgt ctgactgaaa aagaacgtaa
    30361 agaacaaaaa atcgagcagc aaaagcaaga agcagaagaa atcatgaatc agccgaaaaa
    30421 agaacctgac aaaatgaaag tacgtcatga aggtggcgtt gtcattcaag gggtagaaaa
    30481 cttactaatt cgtatcagtc gctgctgtaa tccgattcct ggtgatgata tcgttggtta
    30541 tatcactaaa ggcagaggga tatccattca tcgtcgagat tgtccgaatg ttcagcctga
    30601 caaaccaaat gtagcagaac gtttgattga agtcgaatgg gaagatacat cgaatacacg
    30661 aaaagagtat gatgcagatt tggaaattta cggctataat cgttcaggct tattgaatga
    30721 tgtacttcaa acagtcaatg cgctaacgaa aaatctcaac agcgttgaag cacggacgaa
    30781 taaagataaa atggcgacga tccatttgac ggttggtatc cagaatttat cccacctaaa
    30841 gagtatcgtg gataaaatca aagcagtacc tgatgtctac agtgtacgcc ggacgaatgg
    30901 ataggaggac agatatgaga gcagttgttc aacgggtaag taaagctgct gtgtcagtcg
    30961 atcagcaaga aattggaaaa attggctacg gcctacttgt tttattaggc attcatgaaa
    31021 ccgatacgca aaaagatgtg gactatctgg taaaaaaaat tgcacaaatg cgtatttttg
    31081 aagatgaaca aggaaaaatg aatattagtg tagaagatgt gggaggacaa attttaagta
    31141 tctctcaatt cacactgttt gcggatacga aaaaaggaaa tcgaccaagc tttgtggaag
    31201 ccgcacgacc agaaacagct attcctttat acgaatcatt caatgaagga atcagaagtc
    31261 gcggcatcac agtcgctacc ggacaattcg gagcagatat gtcggtttct ctcgtcaatg
    31321 atggacctgt aacgatcatt attgattcta aaaacaaata aagtaatctg gttttcacta
    31381 gtaaaaacta tgaaacacgt cgcttaagtt agactgataa actctaactt aagtggcttt
    31441 tttgtctgca aaaagcgctt cttttgtcag cagtcggaaa aaaagttaag cttaaattat
    31501 acaagttatt ttttatagga ggttgctgaa gatgaaagaa gtaccagtag tagatatcaa
    31561 aatcacagat ttaaaaaaat tgtatcaaaa aggatacaac atgttggagg agttacgcca
    31621 tgaagcggac gctcccgtcg tcaaagcaaa gattttcaat aaagaagcta tcacgatcta
    31681 cggatcatca gcagcaaaag tattttatga tccaaggaat ttcaaacgaa aaggtgctat
    31741 gccaaaatta gtattgaaga cactttttgg tcaaggtgga gtacagactt tggatggagc
    31801 tgctcatcac catcggaaaa atatttttat ggatctaatg acaccggaaa gaatggaaga
    31861 ttatcatcgt atcttagata agaatctgac acaagcactt gaagcacagc atggtcaatt
    31921 tgaactattt gatttaagta agatggtttt ctttacatct atttgcgagt gggcaggtat
    31981 caatttatca gcgatttcta aagatgaggt cgaaaaatta gcagaatatc aaatctctat
    32041 gatcagcgga acgtttactt ctccgattga tcacataaaa ggtgtcgaaa atcgcaaaaa
    32101 atcagaaaaa tgggcgcaag gcttgattga agaagctcga caaaatcctg tggctggaaa
    32161 agaaaatgtg gcattatatg cttttgccaa tgccacagat ttagatggtc agcttttacc
    32221 tctggaagtg gcagctgttg aattattgaa catcatccgt ccaacggttg ctctaactgt
    32281 gtgggcggca ttgatgggac atgcactttt cagtagacca gatttgtatc agcaattaaa
    32341 aaatgacttt tcgacgttac aagatccgtt tattcaagaa atgagacgct attatccttt
    32401 cttcccaatg ctacctgcga tttcgctgaa agaagtagaa gtagatggtt atcgtatacc
    32461 agaaggcagt tgggttattt tagatttata tggaacagac catgatgaac gaacagttga
    32521 agcgccagat tcctttatga tcaaacggta tgtagggaaa gcaaaagata tttcctataa
    32581 agaagaatat gagatgattg cacaaggcgg gggaaatttt cgacaaatgc atcgctgtgc
    32641 aggagaatgg atcactcttc atagtctacg tgtgttttcc gatcagctag taaataagtt
    32701 tgagttctct gtacctgaac aagattggac gattccattc aatcagtttc cgacttatcc
    32761 gaatagccga gcgctacttt acaagaatta gattagcata aacttatcga aaaaaaggaa
    32821 gatcaaacag tgctgatctt ccttttttca tattactata aattgataag gtcaattgat
    32881 caaaatccac gaaatgcttc atcaatggtt tgataatctt cattggataa atgcaaatct
    32941 aaagcttgga cattgtcaga tacttgctct ggacgcttag ctccaggtat aactacagac
    33001 actcgtggat tcttcatgta ccaagctaaa acaagttgcg caggagtggc ttggtatctt
    33061 ttagcaatgg ggcgaagtac atcgacagcg gttaaaattt ctctgaaacg ttctccttgg
    33121 aaatctggat ttctttttcg aggatctcct tcaccaaatt gtttttcctc accaagttca
    33181 tattttcctg tcagcaaacc ggaagcaaga ggaaaatagg gaacaaaact gattttgttt
    33241 ttttcaagat aagggaataa ttctttttca gcctgccgat ggatcaaact gtatttatct
    33301 tctactacat cgacatatcc atctgcattc gcttctttca attgttctaa cgtgaagttt
    33361 gacacaccga ctgctcggat ttttcctgct tcttttaatt cgtgcaatgt agcaactgat
    33421 tcattttttg gtgtgctttc atccggaaag tggatataaa aaatgtcgat gtaatcagtt
    33481 tgcagacgtt ttagtgcatc ttccaccgat tgtttgagaa actcaggaga attatcaaat
    33541 gttcgccctt tatttggtac atgagcagct tttgtagcga tgacgacacg tgagcgatca
    33601 tattcttttt ccttcagtac ctcgccaatc agttcttcgg aacggccgtt tccgtaagca
    33661 taagcggtat cgatcaaatt gatcccgcta ttcaaagctg tacgaactac ttgttttcct
    33721 gtctcatctt ccaaaccgtc aaaaagatta tgtcctccaa cggcatttgc tcctaatcca
    33781 agctgttctg cgtagacttg tgaatgtccg attcttattt ctgccatagc tgattcctcc
    33841 tttttgtcta gtctaaaaca aaataccaaa aagctgaact aaaacgtttt tgtgagggga
    33901 aatagtcaga tatctcttga ctttgagact ggtttttagt aggttataag taatatcgaa
    33961 tgtcaatgaa agagcgagta agtttttgaa actttacaag agaggatcat cgaggctgaa
    34021 aatgatctaa agtttcatta gcctaaagac actctggaga tggacgagtg aaaagccgtc
    34081 ccgcgtacga gcgttattcg taagaggaaa gagaaatctt tcaaaattag gtggtaccgt
    34141 gtatgaattt cattcaccct tgttcatgat gaacaagggt gattttttta tttacatagc
    34201 taagaaaggg agagaaaact atgagtttcc aaagaccaaa aggaacaaat gatattttgc
    34261 caggcgaatc agaaaaatgg cagtttgtcg aagaaacagc acgtttatta ttcagagatt
    34321 atcagtataa tgaaatgcgt acaccgattt ttgaacacta tgaagtgata tcccgaagtg
    34381 taggggatac aacggatatc gtttcaaaag agatgtatga tttttatgac aaaggggaac
    34441 gccatgtgac gcttcgacca gaaggtacag caccaatcgt tcgttctttt gttgagcata
    34501 aattgttcgg cccagagtat gcgaaaccgt tcaaaacttt ttatatggga ccaatgtttc
    34561 gctacgaacg ccctcaaaaa ggacggttac gtcaattcca tcaaatcgga gtagaagcat
    34621 ttggatcaga aaaccctgca actgatgtgg agagcatggt gatggcactt gatttcttca
    34681 aacagttggg gatcacgcaa atccggctag tcatcaattc attaggtgat aaagaaacgc
    34741 gtcaagccta tcgtcaagca ttgatcgact atcttttacc ttttgaatca gagctgagtg
    34801 aagactctaa acgccgcctt catgaaaatc cattacgcgt attggacagt aaagacaaac
    34861 gagatcaaaa atttgtggca gaagctccat ctatcttaga ttatctaagc gagcctgctc
    34921 aaaaacattt tgataccgtt gtttccatgc tggatgcatt ggctgttcct tatgaaatcg
    34981 acagtaatat ggttcgcgga ctagattatt acacacatac gatttttgaa atcatgagtg
    35041 acgcaccaaa aatgggggca caagcaacga tttgcgcagg cggacgttat gacaatctag
    35101 tggaagaact aggtggtcct tcaacacctg gcttcggatt tgcaatgggt atcgagcgat
    35161 tactcttgac tatggaggca gaggaagtag ttatccctgc atttaatgag ttggatgctt
    35221 acgtggtcgc actcggagac gaaacaaata tcgaagcatt gaaagtggtc caagcgattc
    35281 gaaactttgg tttttcagct gaccgcgact tcatgaaccg taaagcaaaa gcgcaattta
    35341 agacagcaga taaagcgaat gccaaattag tattggtgat cggtgaagat gagcttgcta
    35401 gtcaaacgat taatgtcaaa gcaatggcaa gccgaaaaga aaaaagtttt ccattagaag
    35461 agatatatga acattttgat gaagtctatg atgaaatgac tttattcgag taggaggaaa
    35521 aaaataaatg gcacaaagaa cgatctattg cggattagtt tccgaacaac aattagaaca
    35581 aacagttaca ttaaaaggat gggtacaaaa aagacgagac cttgggggag taatctttat
    35641 cgacctacgt gatcgtgaag gaatcgttca aatcgtcttt aatcctgaaa tcaacaaaga
    35701 agcatgggaa atcgcggata aatgtcgcag tgaatacgtg atcgaagtga ctggggaagt
    35761 tagaagacgc ggagaaaatg cagtaaatcc taaaatggcc actggtgaat tcgaagtgat
    35821 tgcaagtgaa atcgtgattt tgaatcaagc aaaaaccccg ccatttcaaa ttgaagatga
    35881 tcaagcaatc agtgacgaaa tacgtttgaa atatcgttat ttggatctgc gtcgtccaaa
    35941 aatgactaaa aacatcaaat taagaaatgc gacaacaaaa gcgattcgtc attatttaga
    36001 tgataatgac tttctcgata tcgaaacacc ttacctaggg aaatctacac cagaaggcgc
    36061 aagagactac ctagttcctt cacgtgtcca tgctggacat ttctatgcgt tgccgcaatc
    36121 tcctcaattg tttaaacaat tgctgatgaa tgctggattc gaccgttatt atcaaatcgt
    36181 tcgttgtttc cgcgatgaag atttacgtgg agaccgtcag cctgaattta cgcaagtaga
    36241 tattgaaaca acgttcttaa cagcagaaga aatccaaact tacacagagg gattgattgc
    36301 gaaggtaatg aaagaagttc gcggtatcga agtcacattg ccatttcctc gtatgaccta
    36361 tgatgaagca atggctcgct acggcagcga caaaccggat acacgttttg atatggaatt
    36421 gatcgatcta agcgatacag tcaaagaagt agaattcaaa gtcttccaaa tggctcttga
    36481 aaacggcggt gtcgtgaaag cattgaatgc taaaggcgct gcagatcgct actcacgaaa
    36541 agacatggat cagttaggtc aatatgtagg acaattcgga gctaaggggc ttgcatggct
    36601 gaaagtagaa gaagacggat tgaaaggtcc aattgctaaa ttcatgggag aagcaacaga
    36661 agcaatcatt aaagcaacag atgcaaaacc aggtgacttg ctgatgtttg gcgcagataa
    36721 aagtgaaatc gtcgctgctg cattaggtgc tatccggaca cgtttaggaa aagaattagg
    36781 actaattgat gaatcgaaat tcaatttctt atgggtaact gattggccac aatttgaatt
    36841 ttcagaagaa gaaggtcgat atgtctctgc tcaccatcca ttcacgatgc caaaagaaga
    36901 agatatcccg ttattggctg aagaccctgc aaaagtctat gcagaagctt atgatatcgt
    36961 cttgaacggt tatgaactag gcggaggttc tatccgtatt catactcgtg agcttcaaga
    37021 aaaagtacta gaaactctag gctttacaaa agaacaaatg gaagaacaat ttggtttctt
    37081 gttaacagct ttagattacg gattccctcc acatggcggt attgcattag gattggaccg
    37141 ttttgcaatg ttattagccg gagaagataa tattcgtgaa gtcattgcct ttcctaaaaa
    37201 cggaaaagca gcagatgtga tgagtgatgc accaagtatg gtttcgcctt tacaattgtt
    37261 cgaattgaat attgatgtaa cgaatataga agaatagccg ataaaaaggt aaaaaggatt
    37321 tgtcgaatac gcttcttttg acaaccttga tttaattgaa aaacacttta taatgaagcc
    37381 ataacatata aagcggggct tttccatgaa aaaaacattc gaaaattggg cttatcatga
    37441 ttacacgacc aagctttcgg tatctatcgt ttatgcgttg atcgcatcag tcgcattgaa
    37501 tttcttttat cagccaggac atatttattc aagtggtatt actggtctag ctcagatttt
    37561 gacgactttg tcaaaatcac tgataggatt cgaagtaccg gtatcaacaa ctttgtattt
    37621 actgaatata cctttgtttg tattggcgtg gttaaaaatc gggaagaagt ttacaatttt
    37681 cacttttatc acagtcactt tgacctccct ttgtatccat attttaccgg aaacagtcct
    37741 atctaccgat ccaatcatct gtgcgttgtt tgggggggct gtgatgggac taggtattgg
    37801 gctagcgttg agaaacggcc tatcatcggg cggtctagat atcgtgagta tcacgattcg
    37861 taaaaaaaca ggaaagtcga ttggttctat ttcgatctac ttcaatgcat tgatcgtttt
    37921 tgttgccgga attctatttg gctggcaata tatgttttac agtacgttgt ctattttcgt
    37981 cagtggaaaa gtaactgatg tcgtttatac taaacaaaag aagatgcagg taatgatcgt
    38041 aacgaaacat ccagaaaaag tagtaaatga aatccaaaac tgtatgcgta gagggatcac
    38101 gatcatcaat gaagcagaag gtgcttataa gcatgataag cagacagtat tgatgacgat
    38161 cgttacacga tacgaactgc ctctacttag agaagcaatg aaagcttctg atccacaagc
    38221 ttttgtaagt attgcagaaa acgtccagat acttggtcgt ttctatgagg atggcattta
    38281 gatcgagttt gacaaaaatt catgaaatac tgctgtagac agacgttcgt ttgtctgcag
    38341 tttttttcta ccatagtaga atcagcaaag aaaaactgct tttttatttg aaattttctt
    38401 aaagttgaaa aaaagcatgt ttattttttt aaatttatgg gatgatagaa aaaaatagta
    38461 gagaaaggac acgattctac ttgctatttt cacttaatac ccgtatatta cgaatgaaaa
    38521 aagtttatga aaagttggaa tattgaatgg aaaaacaaaa aaggttaaaa aacagccgct
    38581 acatcactgg gtttgatggg ctccgttcat tagctgtggt gggtgttatc ttctatcacc
    38641 ttctgccaac tagtatgaaa ggcggctatt tgggcgttcc gatttttttc gtcgtatctg
    38701 gttatttgat cacggatctg ctgcggcagg aatgggaaca aaatggaaaa atcaatattt
    38761 ggcaatttta tgtcagaaga atgaagagac tctatccggc acttgttttt atgcttgtga
    38821 cagcttcggc ttatatcact ttgtttcagc gagggctgtt aaacaatctt cgaggagttg
    38881 tggtcagcag cttactgtat gtcaacaact ggtggcaaat caataacggt ttatcttatt
    38941 tcgatcgatt tgctaatgag tcaccgttta cgcatatctg gtctttagca gtagaaggtc
    39001 aaaactattt ggtttggccg atcttgtttg tattgttgat ggtatttgtt cgtaaaagaa
    39061 aatggatctt ttatactgtg ttaggtacat ccttcctctc cgccatcttg atgatgatct
    39121 tgtatacacc aggaggcgat ccaacccgtg tttattacgg taccgacact cgtctgtttt
    39181 ctatatggtt gggaagtgcg cttgcgtttg tttggccaag tacgcgttta aagaaaaaca
    39241 tcccgaaaca agcgaaaaat attctgaata tcgctggagg aatctcgctt ttggcactga
    39301 ttctttgctt cttcttttta gatgatcatt acaatttcat ctattacgga ggaatgctcc
    39361 tagtgagtct gttatgcgta gtgctagttg cagtgacagc acaccccgga gcaagtttga
    39421 atcgatggct gacaaatcca gtatttactt ggattggcaa acgaagctat ggcatttatc
    39481 tgtatcagtt tccagttatg attttttatg aagcaaaggt gactgatatt gccgatcatg
    39541 ttttgttgca tactttagtg gaaatcacat tgattctaat catcagtgaa ctttcttatc
    39601 gatatgtgga gcgtccgcta gcacgttttg attatggtcg tacattccaa gtgatgaaag
    39661 gatggttcag caaaccgatc atcagtaaga gcaaaccatg ggttgttcca ggcacattac
    39721 ttgtagcaat tgcactcgtt ggtttcgtta cggcaccgaa aaacgctgta acagccgatc
    39781 aaaaacaact gcaggcaaaa atcgctgaaa gtaaaaaatt agcagaagaa accagaaaca
    39841 attcagaaaa caccactagt tcggttgacc aagcgatcct tgataagtac gagttgtcca
    39901 aggcacaagg gaataaggca caaaaattag aactaacggc atttggtgat tcagttatgt
    39961 tggatgctgc aacggatcta caagaacttt atccaaaagt agtggtagat ggagatgtcg
    40021 gacgacaatt atatgccagt gtaccgtaca ttgaaaaatt aaaggaacaa gatttgttga
    40081 aagacactgt tctgatcgga ctaggaacga atggctcatt ctcggaagct cagtttgata
    40141 gtgtgatgga tgcaatcggt gatcgaaaag tatactgggt caatgtccga gtaccgacga
    40201 agcgctggca aaatgacgtg aatgcgatgc ttgaacagat gacgaaaaaa tacgacaata
    40261 tgacgctgat tgattggtac agctacagta atgaccatag tgactggttt tatgatgatc
    40321 aagtccatcc aaatcctgaa gggatgacac attacattca cttagtcagc gaagccttgc
    40381 taggaggaag ttcaagtacg aacagcagtg agacaaacgt gacagaatga tagctacaaa
    40441 aaacttcagg caaaaacatt tgtttttgcc tgaagttttt ttatatttac cgtgttttta
    40501 acattcatat agattcagga agcaaaacgg ttgagtgtgt ctgtaaataa cgttcttttt
    40561 gttttcgggt gagttttttg aatgcagctt ctgcttttgt tgcttcgctt cttgaagaaa
    40621 atacttctgc atggatcatc ttaacaggtc ttcttttttg aagacgagta tatttagcac
    40681 cagtaccatt gttatgttcc tctaatcgtc tagaaagatc ggttgtatat ccaccataaa
    40741 atgtctgatc tttacagaat aatacgtaaa aataatgttc atttgccata gagcatctca
    40801 cgaatctctg cagtgtattc tccatccata ttgtaagtga tcaatggtgg agcgactttg
    40861 aatccgtcta atttgccttc tttgattcct tcaactaaca aaatatttgc ctcttttcca
    40921 ggttttgggt aaacaaattg gatcctttta ggtgcaattc gatagtcttc catgacctga
    40981 atgatttcta agaaccgatc aggacgatgg accatagtaa agcgtccatt tgtttttagt
    41041 agcttacttg aaatatcgat cacttcttct aacgtcgtat gaatctcatg acgggcgatt
    41101 gccaggtgtt tattagggtt cgttttattt gttggcagcc ctttgaaata aggtggatta
    41161 cagacgacta agtcacaaga attatgtcga acgacagata agctgtcttt cagatcgatg
    41221 gtgtggacag tcatttgttc atttaaatgg ttaagcgcga tactacgtct tgccatgtct
    41281 gctagacgag gttgaagttc gatagcgtcg atagccgcct gggttcgttt acttaaaaaa
    41341 agtccaactg cgccatttcc tgcacaaagg tcaacaatct tccctttttt aggtacacgg
    41401 gaaaagtgag caagcagcac agcatctaaa gaaaaagaaa acactttgga actttggata
    41461 atcttgatat cttctgcgta taattggtcg attcgttcgt cttcgtgaag catggattcc
    41521 ctccaaaatg aaaaaaatag tcgtctgtat tatactattt ttattaaaaa gaaccaaggt
    41581 ggcttgtcaa acctctattt tttatgcata ctatgaccat aagaagggaa aggaagagac
    41641 tatgttttat cgatttatgc gcggggtagt tcgagtacta ttagccttag ttaatggaaa
    41701 tgcccgctat gagaataaag aagttttacc gcaagatgag aattacatac tagttgctcc
    41761 ccatcgtact tggtgggacc cattatatct ggcggtagct gcagcaccca aggaattcag
    41821 ctttatggca aaagaagaac tgttcaaaaa tccagttctg cgatttatat taactcgatc
    41881 caatgctttt ccagttaaaa gagaaaatcc aggaccaagc gtcattaaaa cacctgtaaa
    41941 gattttgaaa tcgacaaatt tgagtttgat catgtttccc agtgggacaa gacatgctac
    42001 agaacttaaa ggcggaatgg cattgatttc cagaatgtct aaagcgaaaa tcgtgccagc
    42061 tgtatatcaa ggtccgttga cacttgggga tctgttcaag cgtcagagag tgacagtgcg
    42121 tttcggcgaa ccaatcgact tatcagatat caagaaaacg gataaagaag gtatggcgga
    42181 gatcgaacga cgaacacaag cagcttttga caaattggac aaagaagtga accctgattt
    42241 caaatatgaa gtcaaaaaaa aataaaatga taagtttatg cgtgggcggt cttttgaatc
    42301 tactgtcctg ttcagttcag actttttcaa tgaaaacgag ggagagacgt caagtctgcc
    42361 ctctttttgc gttccaatat gtaaaataga agacaggtgt catgtaatgg atcaaagtgt
    42421 tataataatt agaaggacat tttttgaggt gattgaatgc gttttttaca tacagccgat
    42481 tggcatatcg gaaaaaaact acaaggttat gacttgattg aagaccagcg tcatgtacta
    42541 tcttctatac tagatatcgc gaaagaagaa aaagtagagg caatcgtgat tgccggagac
    42601 ttatatgata ggagtgtccc agctgttgat gccgtagaat tatacaatga attgatggtc
    42661 gattggaatt taaaggaaaa gatcccgatt tttgctatat caggaaatca cgatagcagt
    42721 acgagacttt cagcgggtac gccatggttc agttattcga actatttttt gcgaacacag
    42781 ctagcagaag catttgaacc agtcgagttt aaaaacgtac aatttttctt tcttccttac
    42841 tttgaaccaa ttgcagcgag attatatttt gaagatgaca atatccgaac gatcaagcaa
    42901 gcggtagcca aggtgataga taaaatgcag gagctatttg attcagaaaa aaaacaagta
    42961 ttgattagcc atttttttgt aatgggaagt gtaaaatctg attcggaaac gaaaatcgaa
    43021 gtaggcgggt tggattcgat ccctggtgaa ctacttacac cgtttgatta tgtagcacta
    43081 ggacatttgc ataatcaagc tgctttgaga caggataatg ctcgctatag cggttcccca
    43141 ttgaaattct ctttatctga gatcaaccaa aaaaaaggcg tatggatcgt tgacctgaca
    43201 acaggcctgg agttgaattt tagggagatc gaacccctgc atgatattga agaaataaca
    43261 gcgagtttca aagaattgct ggatcctgcc ttttatcagt ccgtcaatcg ggagaattac
    43321 atctatatct atctcactga tagaacgatc atcccgaata tgatgaacca gcttcggcaa
    43381 atatatcctc gtattttggg gattgaacgg gcaaacggtc gagcagaaca aacaaagcgc
    43441 aaacgaaaag tactagaaat gaaagatcct caaaaattag cagaagcatt ttttagtgaa
    43501 atgacggaag agcagctaac tgcaaaccaa gaaaaatggc tcggagaaac gttgcaagaa
    43561 atcatggaaa tggaatgatc aagaatgaaa ccgaaaaaat tacaacttaa aaattttggt
    43621 ccttttatca atgagaccgt agatttttca cgtttgacag aagcaccgct ttttttgatc
    43681 agcgggaaga caggagctgg caaaacgacg atttttgatg ggatcacctt cgcacttttt
    43741 ggtgaaactt ccggaagact tcgctctgga aaagagatgc gttctttgtt tgctacacca
    43801 gacgaagaaa caagcgtgac tttttctttt gaacatcagc agatgagcta tgaaatcgaa
    43861 cgaaaaccag aacaagtttt agcaaaacga aaaggaaacg gaacaaaaaa acaggcagcc
    43921 aaagtaacgt tgaccatttt tgatgggaaa ggaaaagaaa taaaacaaat cacaaaacgt
    43981 acagaagcag atcagttgat cagagaactg atgaatctcg atgcgaaaca gttttctcaa
    44041 atcgttttac taccccaagg agaattccgt aattttttgg tttcatcaag cagtgataaa
    44101 gagactgttt tacgtcattt attcggtact caatttttcc aacagttcaa tgagcgatta
    44161 aaagaaaaag caaaacaaca gcaacaaaaa ttggatcatt tagagcaaga gctgcatctt
    44221 ctgcaaaaaa ggtttgtttt agtcaaagaa gaggaaccag cagcagggtt tgaagccgtt
    44281 ttagcccaat ggacaaacca tcaggcaata ctcgaaaaac aaatcacgga agaaaaagaa
    44341 gctctaacgg aacttcagga aaaacaaaag caactagaaa attcctacta tcgttttgaa
    44401 agcttgaaaa aaagttatga agaaaaaacg atattaataa acaagcaaaa ggaattagct
    44461 gctcaaaaag acgaaataga ggaaaagaaa cgatggattg ggtattatga atttacgcaa
    44521 cgattagtcg aaccaatcca gcgcctacaa gaaataaaag ttgaaaaaat agaactgtca
    44581 caaaaaagta gtgagcaaac aaagaaacta gcgatgacta cgcagaatta tgaagagtgg
    44641 caaaaaaatg aagcaaaccg cgtacgccga caaacaaaaa tcaaagaagc tgctcaaaaa
    44701 ctgcaaaaca aacagatgat ggtgccaatt gtcgaatcct tacgtagtaa aaaacaagac
    44761 gcagaacaat taacaatttc attggataaa gaagaattga atgccgagaa gctgtatcaa
    44821 aatctcgcta tctatcagga aagaactcga attcttcaag aaaatttact ggatcaggaa
    44881 aaactgcaag aagatcgtct tgcttttgga cagttaaaat atctagatga aaagcagcaa
    44941 gaaatagaaa aacaaaaagc aaaagacact gggtcgctcg cacagataag agaagaactc
    45001 aaaaaagcaa ctgaagaaat aacaaaaaat agtcagctat tgaaagaaca gacagaacaa
    45061 gcagaacagc tgaaaagcca atgggcaaag cagcaaattg ctcgtcttca gctttttttg
    45121 cgtccagggg agccatgtct tgtttgtgga tcaacggaac accccataca acaattaaaa
    45181 cacgaacagc caaataagga agatatctta aaagtagaac aacaactggc agaagctgag
    45241 tctgctgtag aaagaactca gcaaatcatt gccaaaagtg aagcacatga aaataatctt
    45301 caacaacaat tatcagattt agaacaaaaa atcatggcaa cgaatataca attggctgaa
    45361 caagaagaac acttgcaaca ggctttgaaa aaggcatttc ctgagataac agaacaaaaa
    45421 acaaaaacaa ctcttgtagt aatcgaacaa tctttagata gacgaaaaag caagatggcc
    45481 aatgcaagaa tagagctgga agaaataaga caacaagcag aaaagctcga acaacaatta
    45541 gctgtctaca aacagcagca gacagaaaaa aataatcagc tccagcaact gcaaggagaa
    45601 atcaaaagtt tagaacaaca attgcaagat acggatagta actgtttaga agaggagata
    45661 cgacgacttg aaaaacagtt agaagaagac tcgaatcaac tagctgttga gcagaaagca
    45721 ggagtgcaat tgttgcaaga tcttcatacg cttcggacac agcttgatct tcaacatgaa
    45781 caaatagaaa aaatagatga aaaaatagaa aaggaacaag aaagaatagc taaaaagtta
    45841 gaaagccagt cgtatttttc aacaattgaa gaaatctgtg catttgcaca acagcaagca
    45901 caatataaag aaaaccaacg tacagttact tcttatcatg aagagcaatt agtgacagct
    45961 gaccggctgc gtcaattaga aaatatccag ctaactgaga cattcccaga tacagaagag
    46021 atcagccaac agttagaaga aataagacgt atgatcgaaa taaagcaaga aaagatatac
    46081 ggtttacaag aacaaaaaat tagtaatcaa aaaatctacg atgaatgtct ttcgatttat
    46141 cacacaagcc agacgaaatt agatgagctt acgcaattac agcagctttc gcaaacattc
    46201 aacggagaaa atcctaagaa gactagtttg gaacggtatg tgcttcaggt ttatcttcaa
    46261 gaagtgttac aagtagcaaa tgatcatctc caacgtttaa cgaaaaatcg ttatcaattt
    46321 gagctagcgg ataccattgg cagttatcga gggaaaaccg gattagaaat caatatctat
    46381 gatgatcagg caggtatgtc tcgaagtgcg cataccctgt ctggcggtga gagttttatt
    46441 gcagcacttt ctttagcatt agctcttgcc gatgtgatcc agacacaagc tggtggtgta
    46501 gcaatcgatg cattgtttat tgatgaagga tttgggtcat tagatgaaga agctttggaa
    46561 atggcaatgg aagctttaga aacgatcgaa agtgaaggaa gaatgatcgg catcattagt
    46621 catgtaagag aattgaaaga acgagtatta caacaaataa gaattgatac agaaggtagc
    46681 ggacaaagca aaatacgcta tcaacttgga taaaaaggga gattggtaac tatgaaatgg
    46741 agtattccag aaaaagtcat tgcacgtgga cgtcaatact tgcaagaagg ccgagtgtta
    46801 tcggttgtcc ctgaccaaga agaaaacgtg tggcatgcag aagtcttggg cagtgaattg
    46861 tatatggttg atttggatgg tacagcaaaa gagatagatt actgccaatg tccctattgg
    46921 gaggaacata aatattgtaa gcatacagtt gctgtggaac tttatttacg gtcgaaaaat
    46981 ctatctcgta tcatgaaaaa agaccagcca atgctagaac cggtaaaagc aacaagtgag
    47041 ggagaaatca ttgcaaaagg tttttctcgt ctaaaaacac aaaacaatcc tcaagcggtg
    47101 caacctttga ttattgaata ccaagtagaa acgattgaga ctaatcagta tcacccagag
    47161 ctttctattt tggcacttta cttgcgtatc ggttcattgg catcaccgaa aaaaacatat
    47221 atcgtaaaaa acatctatga ttttttacaa gcttacacag aaaaagaaac ttacactgtt
    47281 aataaacagt accagtttcg tctagataaa cgggcgtttc aaaaagaaga tcaaaaaata
    47341 ctcacgcatc ttgcaggaag tgctcagacg catcaattat taggtacgaa cggcttacaa
    47401 gtcaaaggaa aactagataa aagatatctg cttctcccag tagaacaagc ccgcttcctg
    47461 ttagagcaga tgaatcagac tacacgtttg catctgcaga taaatgaaca aaacgatcaa
    47521 ggaatacaat tttccgatca aaacaaacct ttatcattca aagtggaaaa atttggagaa
    47581 gattatttgc tgcaagcatt gaatgatttt gattttttct ttatgcatta tcagtgggga
    47641 gttatccaag ggacatttta ttctctgacg aaatatcaac aaacggttta tcaaacttgg
    47701 aaacaattga ttcgccgatt ggagaaacca gaagtagtgt tcaagaaaaa agaattaccg
    47761 tctttgttta aagagattat ccctctgctg tcagagatcg gcgacgtagc tattgcccct
    47821 gcagtagaag aggaagtagc agatatcccc gtcgaattta ttttcttttt ccgaaaagca
    47881 aaaggaaaaa tccaagctcg agtcgatttc gtctatggcg aagtcatcta ttcgactgac
    47941 ccgaagcatg aggtctcgac agaacaggct tttcaggtgt tacgtgacac agtagaagag
    48001 aaacgagtac ttgatctatt cagaatgtat cgctaccaga aaaatgaaac tggttatgaa
    48061 cgtccattgc caagcgggga agaactatat gcctttttcc gcacagaact atctgtcttc
    48121 cgtcagtttg gtgaagtcag acttggaaga aaattgcgag agttgtattt agatgcgcat
    48181 aaacatcaac cgaaaatcga agtaaccgag accggttcat ggctcgatat tcgattcgat
    48241 gtgacaggga tagaggagca agaaatcgat catgtcctgc aaagcttgct gagaaatgat
    48301 gctttttata cattagaaaa tggtcaggtt ctttcttttg attcagaaga atttcaacaa
    48361 acaagccaag tgttgcaaca attacgggaa tcgatacgta cagaagaagg aacgatccat
    48421 gtacctaaaa atcaaggatt gatcattcaa aatcaattgg aaaaaagcaa tgctactttt
    48481 agtgaatcgt tccaaacgat ggtacaagat ctcattcatc cagaaagata ccaggcacag
    48541 cttcccaaag gattgaatgc aacgatgaga gattatcaaa agcaaggttt tcgatggttg
    48601 aagatgttag gtcattatca gtttggcggt attttagccg atgaaatggg acttgggaaa
    48661 acactacaga caattgcctt tttactttcg gaaaaagaag aacggaaaag cttctctgct
    48721 ttgatcgtag cgcctgcgag cttaatttac aactggcagg cagaggtgag aaaattcgcc
    48781 ccttctttaa gtatccaagt aatcaatggg aataaaaaag aacgtgaaga attactggct
    48841 aaagacacag atatccgagt gacttcttat gccagcttaa gacaggatct agctaattat
    48901 cagtcgcaaa aaattgatta tttgattctt gatgaggcac aaatggtcaa aaatagcagt
    48961 acgaaaactg cacaagcatt gagagaatta gctgtacctc agcggtttgc actgagtggg
    49021 acaccaatcg agaataattt agaagaattg tggtcattgt ttgcaacgat tatgccagga
    49081 tttttcccga ctaaaacaaa attcagggaa cttgccgcag aagaaattgc gcaaatgatt
    49141 cgaccgttta ttttacggcg agataaacaa actgtgttga aagacttgcc ggaaaaaaca
    49201 gagatgaatc tatattctgc acttacagaa gaacaaaaaa ctgtttattt agcttacttg
    49261 cgtcaaatgc gtgaagaaat cacatcaatg gattctgaag cattcaagaa aaaccggatc
    49321 gggatacttg ctggtctgac aagactgcga caaatttgct gcgatcctcg tctgtttatt
    49381 gaagattacc aaggcggttc cggcaagctc gaacaagtaa aagatctact ggtagctgcc
    49441 aaagagaaca aacgaagagt tttgctgttt tctcaattta cagggatgct gactatcttg
    49501 caagaagagt tagccgagct agggatctcg acattttatt taagaggcag tacgaaacca
    49561 caagatcggt taagtatggt agacgcattt aatgctggcg aaaaagatgt ttttctgatt
    49621 tccttaaagg ctgggggaac tggattgaat ctcacgggag cagatacggt catcttgtat
    49681 gacctttggt ggaatcctgc cattgaagaa caagctgctg gacgtgcaca tcggatcgga
    49741 caaaaaaatg tggtagaagt gtggcgtatg atctctgaag gaacgattga ggaacgcatg
    49801 gattcactcc agcaagaaaa acgcgaactg ttccaaaaag tgatccaagg taatgaagaa
    49861 cagttgacga aactgactga agaagacatc cgcatgattt taagtgtagg agaaatcgag
    49921 gagtaagaga ctcgaaaaag cgttcagtaa tgggtaagaa agcctttcta aagaagcgat
    49981 tgtttatttg atttaaaaaa tagcaaggag gctgggattc cattttatcc cagcttcctt
    50041 gctatcattt ttttatttct atttttaaag gttatacaaa gattgtcttc attgtctcta
    50101 acagctgatc aaaagaagaa atctcgatat cgcaaattgg agtctgttca attttgcgtt
    50161 ctcgatggtt gaaccaaagc gcttgccagt tagcactttt tgcacctaga acatcattgt
    50221 cgtaattatc gccaacgtat aaggtctctt ctggaagcat atgaaattct ttctcagcta
    50281 gctgaaaaat ctctttttct ggtttttgga aacctgttgc ttgagaaatg agcatattgc
    50341 gggaaggaat ccaattgttc aattgaagtt gcttcagttt ttttgtctga tggtcagtcg
    50401 gcccatttgt gataattcct aatgggacat tcttttcctt caagaaatcg agggtttttt
    50461 tgacctcctc atgcaagcag atattatcaa gttcttcctc gtaaattttt tgaaataaga
    50521 ggccatcttc ttccgtaata tgagggtagt ctaaatcttt tagtgattgg ctgatccgat
    50581 gtgctcgcat atattctagt gtccaatctc ctgccattac ttttgggaag ttttcatcac
    50641 tatgatggcg gaaccggata tatagtggat gcatatctgc atctgaaaca agcggaacga
    50701 ctcttttgac cgcgtttcga aatggctgct gctgatcata catcgtatca tcaacatcaa
    50761 acacaactga tttaatcaaa attttacacg cctttcggtt ttcattgatt ttttcacaaa
    50821 tccttgacta ttgtaacaga aaaaattgtc taaaaaagct gataaataaa ggtttttctt
    50881 actatatttc tatttccttg acagaataag gtttttatat ttcagttttt ttcactaaaa
    50941 atcgtgaaac acgtcaataa gtttgatgaa caaattaatc attatggtag aagtcgattg
    51001 atttatttta atgcaatctc tgtggaattt tcgaaagatt tattttttta atacagtctc
    51061 aatataacta ttcaaacata aaataacgtt atttgattta tttgtttata gtaaatttta
    51121 tttagtaatc attgctttaa aatactacgc ttatataaca gagaaaataa gcgttataat
    51181 aaagaacagt attatttaaa atgacagaaa acattactat taaagaaata aaaaacataa
    51241 aaaatcttaa gaaatcggtt tcatttagct tttgagataa aataatagta cagttttata
    51301 cgctgtttca tatgtttaga aaatttgaat tagatttgaa aactctaatt tttaaatgat
    51361 aaaaaaagcg agaatgctgg ttttactgta tattaacctt agataacttt cattttttta
    51421 aaaaaattat gaaaaaaagg tagctattta aaagttgatt atgtataata gaaacagatg
    51481 ggagattatt atgatcttct gttacaaaaa agtgattctt atcacgaaaa ggagtggtgc
    51541 acgttgttaa cattatatac ttccccaagt tgtacttcct gcagaaaggc tcgtgcgtgg
    51601 ttgcaagaac atcagattcc atttgttgaa cgtaatattt tttcagaacc attgaacagt
    51661 tctgaattaa aagcgatttt acaaatgaca gaagacggaa cagaagaaat catctcgaca
    51721 cgttccaaag tattccaaaa actgaacatg gatttagatg atctgccgtt acaagaatta
    51781 ttggaacttg tgcaaaacaa tcctggattg cttcgccgtc caatcatgat tgatgataaa
    51841 cgtctgcaag ttggttttaa tgaagatgaa attcgtcggt tcctaccgcg cgatgtacga
    51901 caattagaat tacgtcaagc acaattgatg gctggattat agaaggataa tacgaaactt
    51961 ggaaaagact attacaaaga tagtttttcc aagttttttt gtttttacaa aaagtattct
    52021 tgattagatg tataaaaagg tagtagaaga tgatgattgc acgaaaaata gagagggaaa
    52081 attagctgaa aagtcggcta tatagtattc gtctgccaaa aatgttatag ttaaataaga
    52141 tagcttgaaa ggttgaaaaa tccgctggtt ttattaaatt cgcttaacag cgagattttt
    52201 tttctttaca tttaagctga tttcgctaca atgaatctat attaaacatt gtggcaaagt
    52261 gaggtgtagc aaaatggaaa tggaacatat taatgaaaat acgatccgtg tactaattgg
    52321 tcatgaagat ttagaggaac ggggcgtttc atttttggat ttacttggca atcacaaaga
    52381 aatcgaaaat ttcttttata gtattttgga agaagttgat atcgaagagg agttccgagg
    52441 aagcgaagct gtcactttcc aagttttgcc aaaaggagac ggattagaac tgtttatcag
    52501 taaaaatctt ccggatgaag aaatttctca atcagaagat tctactgttg attcagaaga
    52561 tgtgagtgac tttcttcgtc agcagattat tggcagcgat ccggaggaag aattatctgg
    52621 aagcgcccta gaagaacagg aaagacaagc aacttttgct tttgaagatt ttgaacaagt
    52681 gatccaactt gcaacagatg tcgaactaga gtctgcttgg actgatttgt atttattcga
    52741 agagcgctat tacctagtcg ttcacttctg gatggaaaat ctcaaccaag cggatgtaga
    52801 gaatcagatt gctcgaattt tggagtttgc tgaaaagagc gatcgtacac cagaaacatt
    52861 gaatgaatat ggacaatgtc tgatggcgcg taatgctatc gagcgaacga aattttattt
    52921 tgtataaatc agcattatag taagagactg tgacaaaaat tgtgtcgcag tctttttttc
    52981 gtataaatgt gttcaaaagc ttgcatctgc ggtaacaagc ccaaccaaac gaaaaatatt
    53041 gggaactatt tttgtttagc tgttcttatt acttgatgca gaatagcttt ttcacgccct
    53101 cttttttcgt gtaaataaat tcttagacgt aaataagttc agagggagaa aaatgctgct
    53161 tgcaatgaat gaatataata agtgctgttt tgctaaacat gcagaaaaag gaaagaaata
    53221 ttattgtcgt ggctgtcgaa aaagagtgat tttgaaaaag ggaaagaaaa aatgtgctca
    53281 ttttgcccat caaaaatcag ataactgttc ggtctttagt gaaagagaat caaaagagca
    53341 cttacagtta aaggaatgct tcatggattg gctgggacag tcagtagaac cagtattttt
    53401 ggaagcctat ttgccgaggt tgcggcaaag gccggatatt ttgttggcga atctagcaat
    53461 agaaatccaa tgttctagac tgtctcacca gagatttatt gaaagaaccc aaaattattt
    53521 gaataacagt taccaagtat ggtggatact tggtaattct tttcttggac aatcgcaatt
    53581 ctcattgata gaaaaaagtt gctgctacta taatagaaaa agaggagtgc attgctggaa
    53641 agctgatctc aagaaacaaa agctttattt gtatcatcat attacagaga ctgtatcagg
    53701 gcatatttcc ttttgcagta gctgctggac tttttctagt agggacctta aagaaatatt
    53761 cactagtaac gaaattaaaa tgaaccaaat gaaaaaaata gaaaaagtga gtgaagatgg
    53821 gaagaaatgg ctgacacgcc aacttattca caagcaaaag aatacagtat ccatacaaga
    53881 acaatgctac ttgcgtcata aacatctttt gcatctatca tcgtggatct atcaaaaaag
    53941 tcggtttttc ttttatttac aagaacaggt ttttctttat cgaatgttgt acgaagaagc
    54001 cttggaaaac cagaaagttc ctgatttcaa ctcatggctt tgccaaataa aagaacataa
    54061 aagggaatgg ctttttccta tgattgatga agagatggtc tatcagcagt tttttaacga
    54121 atgcatacac ttgtcttctt tgaaaaaata gtaagtataa aaataggcta ggaatcggtt
    54181 ttctatgtaa aacaagattt agttatgcta aaattgatgg aagcagacac atgaatgagt
    54241 agaaaagtta gatgctgtga catgtggatg ttagactatg atctattttg atagatagag
    54301 ctaagggaag aaaaggagtg gatttcatgg aagtaaagca gttgccaaaa cgagaagaat
    54361 tgcctgaaaa tttaacttgg gacttgacca agatcttttc aagcgaccaa gagtttgatg
    54421 agaaatattt ggaattatca gaagagttaa aacaatctga aaaacacaaa ggaacacttg
    54481 atcaaggcgc ttctcaattt ttaaatgcga ttgaattcgt attgagggtt tatcgccaaa
    54541 ctgaagtcat ttatgtatat gcgcacctta aaaacgatca agacactgga aatacagatt
    54601 accaagcgct ttatgcaaga gcaagcagtc tgttttcgaa agttagtgaa gccgtttcct
    54661 ggtttgaacc agaaatattg caattgtcag atgaccagat ttggcaatat ttcaaagaag
    54721 aaccaaaatt ggaagtctat cgccattata tccagcaaat agtagataat cgagcccatg
    54781 tcttatctgc tgagcaggaa tctcttcttg ctggagcagg tgaaatcttt gatgcttcaa
    54841 gtgatacatt tgctgttttg aataatgcag atctagtttt tccaacgatt gaaggagaaa
    54901 atggtgaaat agtccaatta tctcatggcg tgtatggtca gttgctagaa agcacggatc
    54961 gaagggtgcg cgaagcagca tttaaggggt tgtacagtgt ttacgaacaa tttagaaata
    55021 catttgcttc tactttaggc acacatataa aaggacataa ttttaaagcg aaagtccgta
    55081 attacagctc tgccagagaa gcgtctttga gcaataatca tattcctgaa agtgtatacg
    55141 atactttggt agacgtggta aacaagcatt tgcctttgtt acatcgatac atggaattac
    55201 ggaaacgttt attagaagtg gaaaaactgc acatgtatga tctttataca ccggtcttag
    55261 gggaagctcc aattaccttt acgtacgaag aagcaaaaga aaaagcttta gaagcactga
    55321 aaccaatggg tgaagaatac atggccatcg tagaaaaagc attctctgaa cgttggatcg
    55381 atgttgtcga aaataaaggg aaacgaagcg gtgcttattc ttcgggaagc tatgacacaa
    55441 atccatatat tttattgaat tggcatgata cgctggatca gctatttacg cttgtccacg
    55501 aaatgggaca tagtgttcat agttatttca ctcgttcgaa ccagccttat gtgtacggcg
    55561 actactccat ctttttagca gaaattgctt cgacaacgaa tgaaaatatc ctaacggagt
    55621 atttattgga aacagaaaaa gaccctcgtg tacgggctta tgtactcaac cattacttgg
    55681 atgggtttaa aggaacagtt ttccgccaga cacaattcgc tgaattcgag catttcatgc
    55741 atacggaaga tgaaaaaggt gtgccattga ctagtgaata cctaagtgat agttatggta
    55801 aattgaatgc aaaatattat ggtccagcag tcgaagaaga cccagaaatt aaattcgaat
    55861 ggtcacggat accgcatttt tattataatt actatgtttt ccaatactcg actggctttt
    55921 ctgctgcttc agcactggcg aagaaaatac taaaccagga accagaggca ctagagaact
    55981 acttggctta cctaaaagca ggtaacagcg attatcctgt ggaagtaatg aaaaaagcag
    56041 gagttgatat gacacaggct gcatatattg aagatgcaat gtcgatgttt gaacaacgtc
    56101 taaatgaatt agaagaattg atcgatcgtt tataaggctt tctatttttg attttctcga
    56161 atagaaacga aaaaaatacg tcggctctct tgtaagggag tcgacgtatt ttttt
//
LOCUS       DAYYEF010000013        54448 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000013 DAYYEF010000000
VERSION     DAYYEF010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 54448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54448
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.013"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(24..959)
                     /gene="murB"
                     /locus_tag="ACHA1B_000922"
     CDS             complement(24..959)
                     /gene="murB"
                     /locus_tag="ACHA1B_000922"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HFM8701703.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1032..1952)
                     /locus_tag="ACHA1B_000923"
     CDS             complement(1032..1952)
                     /locus_tag="ACHA1B_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFM8701704.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2065..2817
                     /locus_tag="ACHA1B_000924"
     CDS             2065..2817
                     /locus_tag="ACHA1B_000924"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HFM8701705.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3681..4214
                     /locus_tag="ACHA1B_000925"
     CDS             3681..4214
                     /locus_tag="ACHA1B_000925"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HFM8701706.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(4704..5228)
                     /locus_tag="ACHA1B_000926"
     CDS             complement(4704..5228)
                     /locus_tag="ACHA1B_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase family protein"
                     /protein_id="HFM8701707.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(5221..5694)
                     /gene="tsaE"
                     /locus_tag="ACHA1B_000927"
     CDS             complement(5221..5694)
                     /gene="tsaE"
                     /locus_tag="ACHA1B_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002949 - tRNA threonylcarbamoyladenosine
                     modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HFM8701708.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(5817..6797)
                     /gene="pta"
                     /locus_tag="ACHA1B_000928"
     CDS             complement(5817..6797)
                     /gene="pta"
                     /locus_tag="ACHA1B_000928"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008959 - phosphate acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HFM8701709.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(6950..7630)
                     /locus_tag="ACHA1B_000929"
     CDS             complement(6950..7630)
                     /locus_tag="ACHA1B_000929"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HFM8701710.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            7756..8625
                     /locus_tag="ACHA1B_000930"
     CDS             7756..8625
                     /locus_tag="ACHA1B_000930"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM8701711.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            8651..9166
                     /locus_tag="ACHA1B_000931"
     CDS             8651..9166
                     /locus_tag="ACHA1B_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related/scramblase family protein"
                     /protein_id="HFM8701712.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(9213..9776)
                     /locus_tag="ACHA1B_000932"
     CDS             complement(9213..9776)
                     /locus_tag="ACHA1B_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8701713.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(9831..10010)
                     /locus_tag="ACHA1B_000933"
     CDS             complement(9831..10010)
                     /locus_tag="ACHA1B_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701714.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(10087..10596)
                     /locus_tag="ACHA1B_000934"
     CDS             complement(10087..10596)
                     /locus_tag="ACHA1B_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701715.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(10692..11072)
                     /locus_tag="ACHA1B_000935"
     CDS             complement(10692..11072)
                     /locus_tag="ACHA1B_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM8701716.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            11402..12151
                     /gene="pnuC"
                     /locus_tag="ACHA1B_000936"
     CDS             11402..12151
                     /gene="pnuC"
                     /locus_tag="ACHA1B_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015663 - nicotinamide mononucleotide
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015890 - nicotinamide mononucleotide
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HFM8701717.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(12472..13689)
                     /locus_tag="ACHA1B_000937"
     CDS             complement(12472..13689)
                     /locus_tag="ACHA1B_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFM8701718.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(13947..15224)
                     /locus_tag="ACHA1B_000938"
     CDS             complement(13947..15224)
                     /locus_tag="ACHA1B_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701719.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15303..15947)
                     /gene="pcp"
                     /locus_tag="ACHA1B_000939"
     CDS             complement(15303..15947)
                     /gene="pcp"
                     /locus_tag="ACHA1B_000939"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFM8701720.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16146..17090)
                     /locus_tag="ACHA1B_000940"
     CDS             complement(16146..17090)
                     /locus_tag="ACHA1B_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFM8701721.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17092..17778)
                     /locus_tag="ACHA1B_000941"
     CDS             complement(17092..17778)
                     /locus_tag="ACHA1B_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFM8701722.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            18252..18572
                     /locus_tag="ACHA1B_000942"
     CDS             18252..18572
                     /locus_tag="ACHA1B_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFM8701723.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            18726..19631
                     /locus_tag="ACHA1B_000943"
     CDS             18726..19631
                     /locus_tag="ACHA1B_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701724.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            19628..20401
                     /locus_tag="ACHA1B_000944"
     CDS             19628..20401
                     /locus_tag="ACHA1B_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFM8701725.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(20582..22006)
                     /locus_tag="ACHA1B_000945"
     CDS             complement(20582..22006)
                     /locus_tag="ACHA1B_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFM8701726.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            22217..22663
                     /gene="nrdI"
                     /locus_tag="ACHA1B_000946"
     CDS             22217..22663
                     /gene="nrdI"
                     /locus_tag="ACHA1B_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFM8701727.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(22728..24710)
                     /locus_tag="ACHA1B_000947"
     CDS             complement(22728..24710)
                     /locus_tag="ACHA1B_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFM8701728.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(24724..25620)
                     /gene="murQ"
                     /locus_tag="ACHA1B_000948"
     CDS             complement(24724..25620)
                     /gene="murQ"
                     /locus_tag="ACHA1B_000948"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFM8701729.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(25623..26684)
                     /locus_tag="ACHA1B_000949"
     CDS             complement(25623..26684)
                     /locus_tag="ACHA1B_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFM8701730.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(26895..27422)
                     /locus_tag="ACHA1B_000950"
     CDS             complement(26895..27422)
                     /locus_tag="ACHA1B_000950"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFM8701731.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(27489..28991)
                     /gene="eat(A)"
                     /locus_tag="ACHA1B_000951"
     CDS             complement(27489..28991)
                     /gene="eat(A)"
                     /locus_tag="ACHA1B_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFM8701732.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(29249..30370)
                     /locus_tag="ACHA1B_000952"
     CDS             complement(29249..30370)
                     /locus_tag="ACHA1B_000952"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFM8701733.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            30496..31437
                     /locus_tag="ACHA1B_000953"
     CDS             30496..31437
                     /locus_tag="ACHA1B_000953"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFM8701734.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(31587..32483)
                     /locus_tag="ACHA1B_000954"
     CDS             complement(31587..32483)
                     /locus_tag="ACHA1B_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFM8701735.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            32752..34092
                     /locus_tag="ACHA1B_000955"
     CDS             32752..34092
                     /locus_tag="ACHA1B_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFM8701736.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            34310..34753
                     /locus_tag="ACHA1B_000956"
     CDS             34310..34753
                     /locus_tag="ACHA1B_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFM8701737.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(35257..36675)
                     /gene="nhaC"
                     /locus_tag="ACHA1B_000957"
     CDS             complement(35257..36675)
                     /gene="nhaC"
                     /locus_tag="ACHA1B_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFM8701738.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(37078..38301)
                     /locus_tag="ACHA1B_000958"
     CDS             complement(37078..38301)
                     /locus_tag="ACHA1B_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HFM8701739.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(38332..39171)
                     /locus_tag="ACHA1B_000959"
     CDS             complement(38332..39171)
                     /locus_tag="ACHA1B_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HFM8701740.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(39188..39868)
                     /locus_tag="ACHA1B_000960"
     CDS             complement(39188..39868)
                     /locus_tag="ACHA1B_000960"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease"
                     /protein_id="HFM8701741.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(39870..40943)
                     /locus_tag="ACHA1B_000961"
     CDS             complement(39870..40943)
                     /locus_tag="ACHA1B_000961"
                     /EC_number="7.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0033232 - ABC-type D-methionine
                     transporter activity [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0048473 - D-methionine transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HFM8701742.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(40999..41237)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(41280..41513)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(41590..42261)
                     /locus_tag="ACHA1B_000962"
     CDS             complement(41590..42261)
                     /locus_tag="ACHA1B_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM8701743.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(42348..44996)
                     /gene="mgtA"
                     /locus_tag="ACHA1B_000963"
     CDS             complement(42348..44996)
                     /gene="mgtA"
                     /locus_tag="ACHA1B_000963"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015444 - P-type magnesium transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HFM8701744.1"
                     /translation="MEKKKDTQKIYAAFAGKTKQELFELFHASANGLTEEQIERSREN
                     YGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPGDKDLFGVAII
                     FTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEEIVCGDLVRLS
                     AGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSYENLVFMGSNV
                     ISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKFMSLMAPAVIV
                     INGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGTVIKNLNAIQN
                     FGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQTGLKNLLDVAI
                     IDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGAIEEMLNISKF
                     IDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFSVKDESDMVLI
                     GYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLEINELVTGEKI
                     SEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGINDAPAMKVADI
                     GISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKATASSNFGNMFS
                     VLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKWNASSIGEFMV
                     YFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAGWFVESLWTQT
                     LVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLMPLPGNYWLWL
                     FATVIAYLALVTAVKKIYIRRFQELL"
     regulatory      complement(45338..45512)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            45685..46122
                     /gene="ndk"
                     /locus_tag="ACHA1B_000964"
     CDS             45685..46122
                     /gene="ndk"
                     /locus_tag="ACHA1B_000964"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HFM8701745.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(46144..47010)
                     /locus_tag="ACHA1B_000965"
     CDS             complement(46144..47010)
                     /locus_tag="ACHA1B_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFM8701746.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(47170..49263)
                     /locus_tag="ACHA1B_000966"
     CDS             complement(47170..49263)
                     /locus_tag="ACHA1B_000966"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFM8701747.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(50012..50635)
                     /locus_tag="ACHA1B_000967"
     CDS             complement(50012..50635)
                     /locus_tag="ACHA1B_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701748.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(50794..52191)
                     /locus_tag="ACHA1B_000968"
     CDS             complement(50794..52191)
                     /locus_tag="ACHA1B_000968"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFM8701749.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(52223..53194)
                     /locus_tag="ACHA1B_000969"
     CDS             complement(52223..53194)
                     /locus_tag="ACHA1B_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8701750.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            53568..53993
                     /locus_tag="ACHA1B_000970"
     CDS             53568..53993
                     /locus_tag="ACHA1B_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701751.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT        15717 a        11284 c         9619 g        17828 t
ORIGIN      
        1 cttattttaa gttccattac ttattaattg gctaaacttc tgcttgtttc tgatattgct
       61 tgtttttctc caatgatccg cacttctgtt tctaaagaca catcaaattt ttctttgatt
      121 acttcttgga tgtgcgcaat caattcaata taatctgtcg ctgtcgcatg atcgatattg
      181 acgatgaatc cagcatgttt ttcagagact tgtgcaccgc cccatttcag gccttgcaat
      241 cctgcttgtt ggatcagctg acctgtatag tgtcctactg ggcgcttaaa gacacttccg
      301 catgaagggt attctaatgg ctgttttgat tgacgcaatt cggtcaactc atccattctt
      361 gctttgattg cttcataatc ccctgtttgc aaactgaatc gagcttccaa tacgatagca
      421 cgtaattctt ggactttact gtgacgataa gaaaatacca tttcgtcttt tgtcaaagtt
      481 ttcaatgttc catcttcaag caaaagatcc acttcagcaa aaacatcttt gatctctccg
      541 ccatacgcac ctgcattcat ataaaccgct ccaccgacac ttcccgggat gccgcaagca
      601 aattcaaatc cagtcaatga ttctgccaaa gctgcataag tcgtatcaat cagtgaggca
      661 cctgcttccg caatgaccat cgttcctttg acatgaatct gtttcatttc agtcagcatg
      721 atgactacac cgcgaatccc gccatcttga acgatcagat tgcttgcatt tcctaatacc
      781 atccaaggta tatcatggat tcggcaataa tcgatgattt gctttacttc ttcttgtttt
      841 ttcgggaatg caaggacatc agctggtcca cctgttttcg taaacgtata gttcatcaat
      901 ggttcatcaa acaatatagt aatcgtggct aagctttcaa ctatttcttc tttattcact
      961 gaggattttc ctttcttttc tcaaacgtcc tcattattct atcacgctta atacaatctt
     1021 gccagtcttg ttcaaagttg atgacggtag tgatctttaa gcacttcctc acataattca
     1081 tgacttctta caacttcttt ttgtttaagc aattctgttt ccgatttacc taaacggatc
     1141 tgagaaaaga aggcctctac cattggctca aacccgcgtt tgactagcgt gtttgtccag
     1201 tcgccaaatt ctttcacttt ttttccatca gcatcttgaa tgacaagctg ggtcagatcg
     1261 tttacttcat aagtaccatt tttacttgtt acttgatatt tttctatatt agcgccactt
     1321 gctaaatcca tcgttaaaat agccgtttga ttttgtgttt ctaattgtaa aatggcatat
     1381 tccaaaaatt cctttgtttc tcttatctgg tattttgttc tcaaaatggg ttcatctaat
     1441 aaatacacag ctgtatcaat aagatgtaaa aacaaatcat aaaggacgaa ctctgtcgtt
     1501 tcttttgccg ctattcgatt tttttgcagg tggatcaacc gcttatctgg gatacgtttc
     1561 aattcttcta ccataggagc aaagcgccgg ttgaaaccga tcatcaaaat tatttggttc
     1621 ttatcagcta attcttgcaa ttcacgaact tcatttagat ggacactcag tggtttgtca
     1681 atataaacat ggataccatt ttctagacat tttttggcta attcataatg tacttttgtt
     1741 gctgcgtgga tcatacatgc ttcgattttt tcttctaaaa gctcatcgat cgtttcatat
     1801 agatgttgga acccgtactc tttttgaatt ctttcttttg tttctttatt tcttgttgca
     1861 aaataaaaat caagtgttcc ttgttttttc gcataagttg gtaaatatgc tttttctgcg
     1921 atattcccta caccgattac accaatcttc atctactttc ctcctggatc atttagttac
     1981 tttcatctta caccattttt tactaaaatg aggtacaata gtatcgcaaa ggtaaggaaa
     2041 ttaattcgaa ggagtgtgct tttattgaaa tttatctctt ggaacgtaaa cgggcttcgt
     2101 gccatcgtaa ataaaaattt tttagaagtt tttcatgagt tagacgccga ttttttctgt
     2161 ctgcaggaaa cgaaactcca agcaggacaa attgatttag atcttccagg ttattatcaa
     2221 tattggaatt acgcggaacg aaaaggctat tccggcacag cgatttttgc taaaaaacca
     2281 gcattgaatg ccacttacgg aatgggtatc gatatccatg atacagaagg ccgtctgatt
     2341 actttggaat attccgattt ctttcttgta acctgttaca cgccaaattc tcaaagcgaa
     2401 ttaaaacgtt tagattaccg attagaatgg gaagaagcct tttataatta tttggaaaat
     2461 ctaaaaaaac aaaaaccagt catcgtgtgt ggggatctaa atgtcgctca tcaaaagatt
     2521 gatttgaaaa actggaaaac gaatcaaaaa aatgctggat tcactccaga agaaagagcg
     2581 gctctttctc gactgttgga taacgggttt atcgatacat tccgttattt ttatccaacc
     2641 caggaaggtg tctactcttg gtggaactac cgattcaatt caaggaaaaa caatgctggt
     2701 tggcggatcg attacttttt gacgagcaaa gatttagagc caggactagc tgatgcaaag
     2761 atccatacgg acattatggg cagtgatcat tgtccagtag aattagattt gaaataaaga
     2821 ggttgtgaaa aagtcgttta gtttcgagta ttaagaaaaa ttttgtgaaa atggctttcc
     2881 acattttgca taaatttggc ataataccga gaaactggct tttgaacact gtttatcgag
     2941 agattgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaaacaaa aatagttcct
     3001 catatttttc gtttggttgg gcttattacc gcagatacaa gcttttgaac accgtttatt
     3061 aagaggttgt gaaaaagctg cactgcatca agtaataaga acagccaaac aaaaatagtt
     3121 cctcatattt ttcgtttggt tgggcttatt accgcagatg caagcttttg aacaccgttt
     3181 attaagaggt tgtgaaaaag ctgcactgca tcaagtaata agaacagcca aacaaaaata
     3241 gttcctcata tttttcgttt ggttggactt attaccgcag atgcaagctt ttgaacaccg
     3301 tttattgaga agttgtgaaa tcagcgtcct gacctgagta ttagagaaac aaatggcaaa
     3361 atagttcctc atattttgct attttttgag ctaataccga gggtcagctg attgaacacc
     3421 gtttagtgga gaagttgtga aaaagtcgcc tactttcgag tcgtaagaaa tttttttgaa
     3481 aatggttcct cacaactttg cataaatttg acttaatacc gagaagtcat gatccccatc
     3541 taactccaaa tcacaaggaa tgagttcaaa aactagcttt tctcaacaaa tattacataa
     3601 aaaattctat gttttttgtt aaatttattt gcttttttca aaagtatgtt acagtaattt
     3661 cccaaggagg ttttacagaa atgaattttg ttgccatgga ttttgaaact gccaatcatc
     3721 agccttatag tgcttgttct cttgcgctag tcatggtaaa aaatagccag atcgttgatg
     3781 aattctatac attgatacag cctgagactc cttttttctg gcgaaatgtc caaattcacg
     3841 gaatccatca agaagacgta cgcaatgcgc cgaaattccc agaagtctgg caaactatcc
     3901 aaccatattt tcaaaaaaat cgtttagtcg ttgcacataa tgctgctttt gatacaaagg
     3961 tcttagcggg atgcttagat tattatcatc ttgaacagcc taattatctt tctttatgta
     4021 cagtgaaaag tagccgtcgc ctgtttcctg aatttccaaa tcatcgattg aacactgtgt
     4081 gcgaaaattt gaacatccaa ttagatcatc accatgatgc attggaagat agtcgtgcat
     4141 gtgcggaaat cctgctttat caagaaaaaa aattcgggac agatccattg aaaaaacttg
     4201 tgactataaa gtaaaagaat acttatgaaa cacacaaaga ggtcgtgagc ctgccgtttc
     4261 actccgagtc acaaggagca atttcaaaaa atagcttctc atgtttatta aatattgtga
     4321 ctggtgaccg aggagctggc aggagaacac cgtttattgg agaggttgtg aaaaagctgt
     4381 tctgcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt tcatttggtt
     4441 ggacttatta ccgcagatgc aagcttttgg acaccgttta ccaagaggtt gtgaaatcag
     4501 cgttttgacc tgagtattag agaaacaaac ggcaaaatag ttcctcatat tttgccgttt
     4561 tttgagctaa taccgaaggt cagctgattg aacaccgttt attcaaaaaa aatggactgc
     4621 gacacgactt ttgtcacagt cccttcgtgt gtttttctgc cttctcaaaa ggatgacagt
     4681 ttctcactct tttcctattt cttctattca atcaaataac tcattttata tacatctaaa
     4741 aattcaccta gatctgttct tgcccctcta ggcatgaccg cttcgatttg gaagcccatt
     4801 tttcggtaaa ggtgtacggc tctttcatta cgaacttgaa cgtcaagctc caatcgaaaa
     4861 agtacaccca tttccttcgc ccaactgatg atttcttcta gcataagagt gcctagtccc
     4921 attccccaat attcctgcag aatactgata ccgacttctc ccacgtgaga caaacgaaat
     4981 tgactgtctg ccttgacaga tgctgttcca ataatcgtcc cttcatagat tgcaagcagc
     5041 aataaattat tattgctttc gtatatataa tccaactctt cttctaaggt ttctggtggt
     5101 aacaggagtt ctgcttcatc caaaactaaa aattctgtct ccttattaac ttgtcccatc
     5161 atcaaaagaa tgtcttttgc atctcctggc actgcttccc gcaagatgat cccaacttct
     5221 tcactcatga ttttcagccc atttttctag aattcgctgt ttgaaggttt cactttgctc
     5281 cccgtatgag attagtttca cataccgctt ttctaaatct gtatcacttt tttctaaaat
     5341 cagttccaaa taatcctccg gcagtgcttc ttctaataga tttccccatt caacaacgga
     5401 aagcccatca ccttcaaaat attcatctaa ccctaaatct gctccgctag ctgctacccg
     5461 ataaatatcc atatgataca acggaatccg accttgacta tattctctaa taatcgtgta
     5521 tgtcggactt ttgatcattt gcgttatccc taatccttgg gcaattcctt tcgtcaacgt
     5581 tgttttaccc gcacctagat caccagtcaa tatcagattg tcacctggca ttgcggaatg
     5641 accaattgcc tctgcgaatt gttctgtcat tgttaatcct gatagttcga tcatttttca
     5701 tcttctcccg ctcttctttc tttttgccag tatatcgcgt aatgaagttt ttttaaagaa
     5761 aaaatgaact agtcaagaac agcagctgct gtttttggct agttcgcgtg tatttgttaa
     5821 tcaatcaatg tttgtgctgc tgtgataatc gataatttat atacatcttc ttcatttgct
     5881 ccacgagaca aatcagaaac cggtttgttc aagccttgta gaattggtcc gattgcttca
     5941 aagttaccga aacgctgagc aattttatag ccgatatttc ctgactgcaa ttctggaaat
     6001 acaaagactg ttgcttgacc agctacttct gaatctggcg ctttcagttg tgcaactgaa
     6061 ggaacataag aagcatcaaa ttgcaattcg ccgtcgatca tgtattgtgg cgctagtttt
     6121 ttagcgattt tagttgcttc aactactttg tctacttctg gcgatttcgc tgagcctttt
     6181 gtcgagaagc tcatcattgc tacttttggt tcgatatcga acaattctgc tgtttttgca
     6241 gaatctacgg cgatttcagc caattcttgc gcagttggat tcacgttgat cgcacaatcc
     6301 gaaaagacat atttttcttg atctcttcca cgtaccatga tcatcgctcc gcttgtccga
     6361 ctgatgccag gctttgtttt gatgatctga agtgctgggc gaacagtgtc gccagtcgaa
     6421 tggatcgctc cagagaccat tccgtctgca atccccatat acgtaagcat cgtaccaaag
     6481 taattcacat cttttaaaat cttttctgct tgttctttgg atgcctttcc atttctacgt
     6541 tcaacaaaag tatccaccat ttcatcccac ttatcgtaat tatcagggct gatgatcgta
     6601 aagctagatg ttttgattcc tctggcatgc gctgcatttc ttatttcttc ttcgttccct
     6661 actaaaatgg gttccacaag ttcttctgct ttcaaccggg cagctgcgcc taaaatacga
     6721 gcatcagtag cttccgggaa aacgattttg atcccacggc gaacaatttt aaatcttaaa
     6781 ctatcaaaca attccacaag atgacctcca gacgttttta tatgtattat catacactat
     6841 tccagaaaaa aagaacagtt tattttatct gtatcagtca aaaatgctgg aaaaattaag
     6901 tttttcacat acaaagcgaa ctgcactata acaggaaagc gctgttttat tacactgttt
     6961 caggcagttg ccaatcaatc ggttcttctc ctaacgcaag gagcgcatca ttcgttttcg
     7021 agaagggttt ggaaccaaaa aagccacgac ttgcagataa cggactggga tgtggagatg
     7081 ttatgatgat atggcgactc ttatcgatca ttttgatttt ttcttgtgcc ggttttcccc
     7141 acaagataaa cacgattggt ttttcccgtt catttaattt ttcaatgatc gtgtctgtta
     7201 atctttccca acctttcccg cgatgagaat acgcttgccc ttcccgaacg gtaagaacgg
     7261 tgttgagtaa aaggactccc tgtttagccc atgacactag atttccatgt tgaacaggtg
     7321 cgattccaag atcatcataa agctctttat agatatttct taacgatggc gggatcttta
     7381 cgccaggttg cacagaaaaa gataagccat gagcttgatt ttctccatga taaggatctt
     7441 gtcctaaaat caccacttta acttcttcat aaggagtcaa ttccaatgct tcatagatat
     7501 gatacatatc tggatggatc ttttgggacg catattcttt ttttaaaaat tctcttagat
     7561 gcagataata atcttttgaa aattctgagg acaaaacttc ttgccaactg ttatgaatga
     7621 tttctttcaa aaactccacc tcctaataaa aagaataact cacattttct tcaatcacaa
     7681 gggacaatct tcaccctcag cacttgatta atatggtaaa ctaggaacaa gaagcagaaa
     7741 ggaacgataa tcattatgat caaattaatt gcatcagata tggacggcac attattagat
     7801 gcccatatga gtgtttctcc tgaaaatgcc gaggcgatac gttttgcaaa tgatgccggt
     7861 gttgagttca tggtcgctac tggtcgaaac tatcaagaag ctcgcgcagc tttagatgag
     7921 gtaggaatcg attgtgcgat gatcactttg aacggggcac aggtatttga taaagaagga
     7981 aattcattgt ttaccgtgtc gattccaaat aatcaagcaa tctctgtttt agatattcta
     8041 gatgctaacg gtatttacta tgaagtagca accaacgatg gtctttattc tgaaaatcaa
     8101 gcgaaacgaa ttgaaagttt tgcttccatg gtggctaccc atttacctca ccttacgtat
     8161 aaaatggcga ttgccatggc ctcagctaag ctggagttat tgcacatcac atacgtggac
     8221 agtattcgtg ctattttgga agaaaagaat ctggaagttt taaaaattat ttgttttcat
     8281 acagaagggc cagctgtatt aggtccagtt ggaaagcaga tttctctttt aggcgatcta
     8341 gccgttactt cctctggtca aaacaatatc gaagtgaacc ataaaaacgc tcaaaaagga
     8401 attgctgttg cccatgtcgc tcacgagcgt gggatttctt tagaagaagt catgacgatt
     8461 ggcgataact tcaatgatgt cagcatgctg caagtagcag gagtcagttt cgcaatggga
     8521 aatgcagaaa tcgaagtaaa agattatgcc aaatatacaa cggacacaaa ccttgaatct
     8581 ggcgtaggaa aagccatatt gcgcgcgatt gcagaagact tgtagtttta tctagaaaag
     8641 agggatatag atgtcagaat ttttcattca ggaaaagcag cttggacgtg caactcggac
     8701 aattgtcaaa aacgaaaaag gacattccct gtttttgatg gttggtcgct ggggaacaaa
     8761 gggcgatgca ttgtctcttt atgccatgaa tggcgatctc gttgctcaca tcaagcagat
     8821 aagcctgaca ttcggtacgc gttttgagct gtataaagag ttcgaaaagg tgggaaccat
     8881 gcagaaaata ttcaattggc ccggtgactt ttattatatt cgtagacttc actggacagt
     8941 ccaaggtgat atctataatc atcaatatca aatccatcat ttcaatcagc aaatcatgaa
     9001 aatggataaa gcaacacttt tttcaggaga ttactatgta ttggatgtct caaatgatga
     9061 agatgctcca gtttgtattt gtattgctgc ggttttagat tactggctct accgtaaaga
     9121 caaaagtcgc gataagcctg tttcttaccg acttaactta agttaaaaag atgtacctga
     9181 aatgcggaaa tacgcatttc aggtacatct ttttagatat tcttttgcat atgatcataa
     9241 agatgaccac tgatcatccg ctgaccgaca actttgaagt catggcgttc gtataatttt
     9301 ttagcctttg gatttttttc atccacactt agaccgatga cggagcgatt agctttcttc
     9361 gccaatttag gtaatgcttc taataatcgc gaaccgatgc cttgtcctct aaaatcttct
     9421 gatacactga tagagtccaa ataccattcg ttgggaaacg tttctttatc aatgaacaaa
     9481 cgtgtagacg catctagctg atatttctct aagataggta ccagtggctg atcgatgatt
     9541 gattcttctt catctgtata accgtaagca actcctgcaa ctttaccgtc tatttcttct
     9601 acgatacctc gtgaataact gtaacgataa tttggatcag tgattgcttc ttctaaaatc
     9661 tctaaagtct tttgttcccc tgtctgcttc aaaaatggca gttccatatc ttttagaatc
     9721 actaagatca atggggcgat ttctggagca tcttcttttc tcgcaaaacg aatcatagtt
     9781 tcctctcctt ttctccattc taacatgcag aaaaagaaat cgcaaaatcg ttattttaaa
     9841 aaatcttcaa tcttttcagt aatgaaataa ccatgagtaa cgattcttgc cgcttcagtt
     9901 cggcaataag ggcagacgac tggcatttct ttatcattat gttcgactac attattgact
     9961 tcttcgtatg caaatttttt tccgcaatta gggcatttca ttttttccat gttatctcaa
    10021 cttcctttca tctttactct cttagcttac tcttatattg taaaaaagag aagcaatatc
    10081 cttcttctat gcagatatcc atacctgacg gtcctgttct ccatctatta atcggacttt
    10141 ataataagga cgttcatctt tgactagaag tgtccactct ttcacttttg cttttttccc
    10201 gtagtagctg actgcttcct tcatcgctgc ttgcggttgt ttgaactctt ccgttttttc
    10261 tatatcaaaa agatgttctg cggccttttc cgtgtcattt cgtacggttg ttttcccagt
    10321 ggatggattg actgctatga cttgtccttc acaaaaaaac tggtattcat atgttgcatt
    10381 cgtaggattc tccaaatctt tttcaactgc aaaatgaata gcagatatgt tatgttcttt
    10441 tgtttcgttt tttacgattg ctgctgcttt tttcaatgag atccgatatt cctggtcact
    10501 aatatcatcc atgtgaaaag cggcattgag cagtcccgtc ataccggtaa tccctattac
    10561 gatgagggca gcaacaccaa acatcatttt tttcattctt cattctcctg tttctttttt
    10621 ttaaagaata tcaagaaatg aacgaatgaa aaatcgaatg aaacgaaaaa aaagtgacaa
    10681 ttttgttatc tttattcgtg cagttctaat ggcaatccgt ctggatcaaa gaaaaacgtc
    10741 attttttttc ctgtaaaggt atcttctcta atcggttctg attcgatccc taaggactgc
    10801 aattctgcaa ttgtttcttc aatatcgtct actttgaaag caagatgacg caagccacaa
    10861 gcttctggat agtttggtcg ttgtggcgca ttagcaattc caaaaatctc caattcagca
    10921 cttcctagtt tcagatctaa tttatagtca tctcgttctt tgcggtaatt ttctctgatt
    10981 acttcaaatc ctaatttatt aacataaaaa tcacgtgatt tctgataatc tgaaacaatg
    11041 atggctatat gatggatcgt tgtaaggttc atatgagcac tcctattctt cgtttaagct
    11101 cggatctata ttaatctcca gttccattgt aaatgtgtca gattgaaaaa aatagctgtt
    11161 tttccttttt ataagaaaaa aggcaaaaaa aacagaaagt aggtcctcca agacactctt
    11221 cctgttccca atataataaa tgaaagtaag aaattatatt ttcaagaaaa caaacagaaa
    11281 attatcataa cacaaattat ttataattga aagactagtt ttttttcaag aaaagcatac
    11341 aatagattgt gttagtaaat acagaacaca ctacatttag tgtcttaagg agtcctcata
    11401 catgaagtca tattttcagt ttttagctca tcagctaaaa ggctggccgc aacaaaatta
    11461 ttatcttttc tttttcagtc ttggctgcca ggtcatgact cttgtcaata gtcccatcac
    11521 ttggctgtcc gttattacat ttatcggtac cacgcttggt gtattgtgta ttttatccat
    11581 caatgcggca aaatcagtca acggtatttt aggtattttg tctgcgattt gttttattat
    11641 cgttgggttt tcagcaaaga actatttaag tatcggtgaa cagattgctt atatgatcac
    11701 attggatatc cccgtattgt taagtaaaga atggaatcat aatatggctt caaaaatccg
    11761 aaaattcact ggaaaaagct ggtttatcgc aatcatcagt actttccttg tctatcttgt
    11821 ttcaggattc ctgattggtc gttatacaga tgatcctcgg ccgtgggtag atgccattgc
    11881 tttttctatt agcttgactg ctggtatcat cagtttcttg cgttacaaca accaatatta
    11941 ctggtggtta gcttcagggc ttgctcaaat ggtcctttgg tatatttcat ttacgcatgg
    12001 atctgcaagt ttggcgatgt tcgtgaacag ctctgtttac ttgctgaatg atgtccttgc
    12061 atttaccgtt tcaccttggt ataaccaaaa agaacgtgaa cgtatgcaaa aaatggaaga
    12121 agaatactac aacgcacaac aacacgcata aaaaaactga gcgtgggaca aaagtaaaga
    12181 acacttttgt ctcacgctct aaacacgtat aaacggcgga atcagaagca actccttcgg
    12241 aaataagctg aaattcacaa aaatttgaaa agcaattttc gtgaatttct tcttatttct
    12301 tggagttaaa cgcttctgtc ccagcctcta tttcctacga ttagtcaagt aaaaggtgca
    12361 agaaaaatag ctcgtaaacg aaagcgacaa aatcaaagca caccaaataa agccccgttc
    12421 gtaaaaaatt ttcgatctgg gcaaagaagt ggtatactgt aagtggttta gttaatggtc
    12481 cactgagacc gcgtacgcat agtcgtactc tgtatgtgcc ctaaccatag cgtgcataca
    12541 tttcagaagc ttgttcatac aagcaactgt ggcaacctta tctttcttag ggataggttg
    12601 cttttttaat ttgtagtaat aatcgacaat atgattagga gctgcgcgtt gctggcgaat
    12661 catatttcga atggtgaaga aaataatttt ccgtgctttg ggattaccac gcttattgat
    12721 gcggtcttgg ccagtatact tacctgaatg ataccgtcgg atgtcgattc cgacaaaggc
    12781 attcaattgt ttatgggttt taaatcgtgt gatatctcct aattcaccga gcaataaagc
    12841 ggctgtgagt gcgccaatcc cagggaacgt ttggtacaac aaaaagcaag gagagccttc
    12901 ggcttttttg atcatttgtg tcgccagtgc ttttttttgt tcgagtaaat cttggagaag
    12961 ttcggcgtaa tagatcgttt tttgacagtg gatactgtct ttttcaacag ctggataggc
    13021 acactgtgca tagtggatga tttgatctgc cttttgctcg gcacgattcg cggagatttt
    13081 tttccgtgtt tcgttgatca gtttattttt tatttttgtc cgagtagatg ccaatacaaa
    13141 atctggatgg ggaaaaagac ggatcaatgt caatgcgtaa ggggtcagcc tgtttgaaaa
    13201 gaactgttca agctctggaa aagtcaattg aaggcagttg tgtaaatcca tgcgcagacg
    13261 agtgattttc ttctcaattt cttgataaaa acgggctaaa tcgcgcatct ctaagtaaaa
    13321 attgctttgt acttcttttg gctgacgttg atttttaaga tgagtctgtg cgagccggtg
    13381 ggcatccgat ttatctgttt tccaactgcg taaggtgctt tcttccatct gttttttcgc
    13441 ctctaacggg tttaacaaac agtaagaaaa gtgatgatct tgaaagaact tttcgactgg
    13501 tctggaataa atccccgttg cttcaaaaac aatcaatgga cgctcaggca agtgctggat
    13561 ctcttcgagt aatgcatgaa atcctctttg agtgtgttca atctcgtctt caaataagca
    13621 ggtgtcgtct ttgtatagga cactgtagct gtgtcccatt gaaacatcta atgcaagaat
    13681 gtaaggcatt tgttttcctc ctttttaagt tttgaaagaa ctttactgct tcatttcgat
    13741 tccaatttcc tatacacggg ctcatggccc caacatacgt aaacctgatt ctaaaatgac
    13801 agtaaagaag ttcggttttt gatagggact cgtagtcctc aaggctttgt tcgaactttc
    13861 tttcactctt cactataatc taaaaataga aaatagagga gaacatcatt cgtcaatgat
    13921 gttcccctct aatcttagta tgttttttat agtaattcct tcagatactt tcttgcctca
    13981 tcattgaaac gcagtgattc ttctaacttc tgataatatt ccaacgcttg tttctgagct
    14041 tcagtaaaac gataatgttt tcctttccat ttgtcgattg tctcttgcac atttccagat
    14101 tggatatctt tcactactag ttgccatttt tcttttgaga ctgtacggtc tttcttatca
    14161 gcagattgta tagcttctcg ttctttacgc aatactttta aaaaaccatt tctgactatc
    14221 cgaggaatgc tgtcgaagaa cccttctgta aaaccatagc gacaatattg cttccaaata
    14281 aatagataga tttttggttg gatgaatcgt tggtttttcg caaaatattc catctgagca
    14341 gtgacttctg gtgttcgttg acgttttgtc tttctcaaca cggaaataaa tgtttcaaaa
    14401 taagcattag gatgtactgg cacttcttca tatacgatgg attgccaatc tttacgtaaa
    14461 aatgcgcgat agttgatcaa gaattcttct acatccttta ctaattcttc tgcaaagtcg
    14521 tcaaatagtt ctttttttat ctgtcgcttt tttgactgcc cattgatgtg ttcacttatt
    14581 ttcttgattt cattttccaa tgcttgataa tccgctatgt aaatcggcat ttctacttgg
    14641 cgaaattctg cgagccgctg agctaatttt atatccggta aatatggctg tttcatccga
    14701 cgattttggt acaagacaaa acagtatttt tgccatagtc cttcaggaaa atcgatattc
    14761 ttctgcttaa gccataataa ttcgtctaag gccagatcaa cttttgtcat tccctgatgg
    14821 atcgaagctg ccactgtcgg agagacatgc aggtgatcgg caaagtggtt gatgcctagt
    14881 tttaggatct ttccggtttt tggcgattta acgatgtatt gcacttttaa ttctctacca
    14941 cactcacaat acaatttttg ctggcttcgt tttgttcgaa aaaacggatt gatcttgaag
    15001 tcagaaaaca cccaatctgt tgcagctaaa taatgttctt ccataaaacg agagctgatt
    15061 agatatcggc ggtgcttatc gactagttcc cgctgttttt tcgttaattt tgcatagatc
    15121 tcccaacgtt gactgcttgt gtattgttta gaaattttga tgggatagct tttgctgatt
    15181 tcttttggaa accattcttc aaagacggat tgccattctt ccacggctgt ttctttcctt
    15241 tctaattaca aaaagctggc tactaacata acgttagcaa ccagccagtg tttcttgcta
    15301 aattagtgag ttgttccggc atttccggaa atatcttctt tattttctac tgctgcttca
    15361 actgcataag tcaaagaaga agcaatgtct tctaaagaca tagaaggcgt acccactgga
    15421 cgatcgatca cttgatcggg tgagaatggc acgtggatga acccacctcg aattgccggg
    15481 aattgtgttt cgatcaaatg aagcaaacga tacatgatat cattgcagac aaatgttcct
    15541 gctgtataag agatgtacgc tggtagacca tgatcttgta cattttttgt cattgctttg
    15601 attggcaatg aggtaaagta agcggctgga ccgttttctt ctaaagccgt atcgaatggc
    15661 tgatttcctt cattatcagg gattcttgct tctgctagat tgattgcgac acgttcgaac
    15721 gagactgctg accgcccacc tgcttgtccg acacagatca cgacatctgg ttggtgctgt
    15781 tggatggctt ctttgactac ttgactgctt ttttcgaata cggtcggtac ttccactttg
    15841 atgatttcag caccgctgat ttcatctggc atttttttta ctgcttcata ggctggattc
    15901 actttgtccc caccaaatgg atcaaaacct gttactagta ctttcatctg ttgttcctcc
    15961 gtccgattga tttaacatat ggttatcttt tatcatacca ttttccttga acagcgtaaa
    16021 taaaggaaac aatagtttaa ataacataac agatcaaact taatatattc ttataaaaaa
    16081 atagtgttcc actacaatgt tagaagaggt tgcgacaatt attctgtcac aacccctctc
    16141 ttctattatt taaatagaat catataagca atttggaaaa ctagcataaa taacgcaata
    16201 aacaactggt ttttgatcac tccgtatttg tctttcatct ccagcatcgc tacaggcacg
    16261 atattgaagt tagcagccat cggtgtcagc agggtcccac aaaaaccgca agtcaatgca
    16321 accattccta ttaacgctgg attcgctcca tgactaaata cgaatggtgc accgatccca
    16381 accgtcatca cggtgatggc cgcaaatgca ttccccatga ttaccgtaaa tatcaccatg
    16441 ccaagagcgt aaatgatgat gccgatgttc acatttcctt ctggaacgat cgtacctact
    16501 gcattggaaa tcactgtccc aactccagcg cttgtaaata ccgcacctag agaagctaaa
    16561 agcattggca acatgcttaa cggccctact gtgcccagca tatctgctgc atcatctaaa
    16621 aatgtacttg gtcgattatc tcgagaaaag aacatcaaga ttagcatggc tgcaaaaaca
    16681 ccgacgccca cgccgactaa agcacctaaa ttggtaaata gagcaaacaa gatcgcaaag
    16741 acaccgatac tcaaagctgg aataaaaatt ttcattccta gtttgtctga cattttttcc
    16801 atatattctt ttgatggaag ccggctttct cctttgctga ctttcttagc aattgctggt
    16861 atggtcatcg caaagatcaa gccaccgttc acgattgccg gaagccatct tcctcctgca
    16921 ataactaccc ctaagaccgt ccagaaaaag gctgacccat aacgatgagg attggtttta
    16981 tctgttaaat ttcttactcc agtgtaaatc aatacgagtc ccatcacgat ataaaggatc
    17041 tccagtaatt tatcgcctaa taaaatatca ggatttgtaa aaaagtccat cttattgccc
    17101 ctttcctgga taatatttct tcgctaattt cttttcttta agatagaagt agacacttgc
    17161 cacaactaaa gccgtgatag ccactggaac ttccactaaa gcaagctgtc ccaatgttac
    17221 gtcatatcct agatctttca gtgttgattg gactagcaac gcccctgctc ctccgatgaa
    17281 tagtacttgg ccaaagaacc agcagacatt ttccatagct gaagccatac cttttagttc
    17341 ttcttcatgc ttaggatgga cttctaaccc ttttgattcg atggtcccca atgccatcgg
    17401 taaaatgatt ggacgaacaa atccagcaac tccaccaaaa ctcacgttaa aagccgcaaa
    17461 gatcattcga aagatcccat aaatatctac aatcatacca gcagatactt tcttgaatcg
    17521 cttgatcaag gaagccgctg attctttcag accatttctt tcaagcgttc ctgttgccaa
    17581 cataatgatg ataaaaatcg ccatcccgcg attgtttaca aaacttgtac ctaaaagttc
    17641 taacattcct tgaatgccaa gaccgccagt caaagctgta acaactaaag caaccattac
    17701 gatcaatatc gagtctaatt taaatgcaaa cccgagaata acaatcaaga cgcctaaaag
    17761 gctaagataa ttttccatat attttcctcc ataaaatgac aatatttttt taattataaa
    17821 gcaaaacaca taaaaaatat agttgttttc tcacgaaata gacactattt ttaaatattt
    17881 ttcgttattt ttttatcaca aaaattatct tacttattgt aaggtaaagc tttttttaat
    17941 ttattgcccg ataatatata gaaataaggt ctagttactg ttttttttaa atgattaata
    18001 aataacaact tctttctatg aaattgcaaa gcattcatct tcttttccgc taacgatata
    18061 tccgtcagtg cttggtacac tttactaaaa agtatgagat tgccgatatc tggataggtg
    18121 tgctatacta cagaaaaaga tatacaatct gccaccgggt aggataaaga ggatgatcat
    18181 tccattaggt ctttgaaggg atgattttcc tctttttgtg tattttttta tagttaagga
    18241 ggaatgtaag tatggcatgg atggaattaa tcatagcagg aattttggaa gtattctggt
    18301 caacgatgat gaaatggagt gatggttttt ctaaaatcaa ttattctttt tacacagtga
    18361 ttggcatgat tgctagtttt tactttttgt caaaggcaat caaaagtttg ccgatgagtc
    18421 tctcttatcc tatctggaca gggattggcg cagttggttc ggtcataatt ggtgtggtct
    18481 tgtttcatga taagctgaat ctttccactt ggttctttgt ggggatgcta ctcatcagta
    18541 tcattggcat caagattact agcggccact agacacttgg aataagtact gatcagaaaa
    18601 aataagcctt tttatttaat attcaatttt tttatgaaaa aataagaaat aagtccaatg
    18661 acctagcgac ttctccactc atcaggtgta tgcttgtact atctatagaa aaggagtgaa
    18721 tatttttgaa aagtctttcg gtccaagaat tatccaagaa ctttggtcac aaacaagccc
    18781 tcagcgatgt cagttttagc ttatcccctg gcaaaatcgt tggattagta ggtcctaatg
    18841 gcgctggaaa aacaacgatc atgaaagcta ttttaggact gatccattac tcagatggaa
    18901 caatctgtat tggtgaaaat gagatttctc cctctagtca taaagggttg gaacaagtag
    18961 gagcattgat cgaatacccg ggtatctatc cattcttaac aggctatgat catctgaagt
    19021 tattctctga aaccaacgat gtatctgcta tcgacactat cgtgaatcag ctcaagatgg
    19081 aaaagtacat tcacaaaaaa gcgaaatcct actcgttggg aatgaaacaa aaattgggaa
    19141 ttgctcttgc cttactgaac catccgtcta tcgttatttt agatgagccg atgaacggtt
    19201 tggatccaca agcaacaaga gatgtgcgaa aaatcattac cgacttggct actcagggca
    19261 cctctttctt gatctccagt cacttactca gcgagcttga aaaaatggtc gatgagctga
    19321 tcctgatcaa tcaaggaaag atcatcaaac aatgtacaat ggctgaattg aaccaaacag
    19381 cgcaagattt catcgttatc tctacaacaa atgatctagc tgctcgaacg atcttgacag
    19441 aagctggata tactttggaa gatcctgata aaatcaagct tttaaaagaa aacgaagaat
    19501 tattaggaac cgtgatccag ctattgtctg cacaaaatat ccatgtgaca gacgtccagc
    19561 atctgacgaa tgatttggaa tcttctctat tggaaattct ggattcagta aagggggaag
    19621 aagaaaaatg acattgcttg taaaacaaga attatttaaa ttgatcaaga aaaagtcaac
    19681 tgctgtttta tctgttctat tagttgtttt gctcatagga acagcacttc tagccaaaaa
    19741 atacacgacg atcattgatc cagttgaaat gactgctcag ctttttagtg ccacatcttg
    19801 gattgtcttt atcatgattg cagctgcaag cacgatcatt tcgatggaag cacaatatgg
    19861 tacattgaaa aatctccttt atcgaaagta ttctcgagga gaaatattag taagcaaatg
    19921 gatcacatta gttatttatt ctgtttattt atacctttta gctattattg tcactgtgtt
    19981 gatgaaactg attcttttcc cttcgatttc cttcacggag aaggtttcta ctggtcaaac
    20041 actgatccaa agcttgttca cttatacttt gggtagttat atcggtttat ggctgatttt
    20101 aagtttagtg ttgatgattg cttgctttat caatagttcc ggcgcatcca tctcagcagg
    20161 aatcgtcttt tattttgctt cgtcaatcat atctggtatc cttattgcac tcatccaaaa
    20221 atgggagtgg atcaaatgga atccgatcag tatgttgaat ctgcaaaacc aaattggaaa
    20281 cgaagagatc atgaagcaat tgactcatct ttctactaat caaatgctat tcggtaattt
    20341 agcttacatc gttttgttct tagcattagg atatctcgta tttaagcgaa aaaatgtatg
    20401 atgactcatc aaaaaagagg ctgtgaaaga gacgttcagc cttattgccg attggctgtc
    20461 tcttaaacac cgtttattct gaaaaaggag ctgtgacaac atttgtgtca cagctccttt
    20521 cctagtatgt ttttgaataa acgacaggct cacaacctct ctttatactt cttttatact
    20581 tctatacgtg aagcatccca gtggcaaata aaaccattgc aatcactccg accatcgtca
    20641 cacctataag taaaatctta tctaagtgga tatgttgtac aggctcgttt tgctccttac
    20701 gtgctttgag gtaaaaataa atgcctggca agaaaagaac aagaacaagc attacttcat
    20761 taaaggctac gactagcata gcccatactt gaaaggcact tgctaaaagc cctactaaaa
    20821 attggaccca ttctttccgc tgataagaaa gtttcatttg gtacaatcct aagaaaagcc
    20881 acgtgaagaa aatagctgct gtaccaagtg tgtaagcaaa gttataagca ctgtcagtga
    20941 ataataatga aagtaaaaag acattcgtac ataacgtcgt caatacgata gcataagttg
    21001 gtgccccatt tttgttgagt tttccccatg ctttaggcaa aagtccgtct tcagccatgt
    21061 ttcccattgt ttcaatcggt aagatcgtcc atgagagcca aacaccaact aaagaaatga
    21121 tcaaaccgcc gttgatcacg actgctcccc atttaccaac catcatttca aacacatagc
    21181 ccatagcagg ctgcgccttg atcgtttgca gctgattcat cgtcattgtc ccatatggaa
    21241 gcatggaaac caagacgtaa ataataatca agccgaatat ccctagaatc gttgctttcc
    21301 caacatctga ttgttttttt gctcgtgaac ctacgacaga ggctccttca ataccaacaa
    21361 atacccaaag catcaccatg atgcaactca atacttgact ggaaaacggg atcggctgtc
    21421 cattcgcatt caatataatg tcgctagaaa agttatcaat gaattgttgg atcgaaaacg
    21481 tgctgatagc tactacaata aataaaaata atggcactaa tttacagaat gtgacgatag
    21541 cattgacgaa actagcattt tcgactcccc gattcactag ccatgcatat ccccataaaa
    21601 agactgtact catcacgatc gatgccagat tttgcccacc ttcaaatact gggaagaaat
    21661 atcctaatgc gctcatcaac aatgttgcaa aagctacgtt gcctaaccag catgtgagcc
    21721 agtaacccca accgctgata aaaccagcga aacggccaaa accttcttct gcgtaactaa
    21781 agatcccgcc ttttaaatct ggacgttttt tattgatatt attgatcgac aaggagagca
    21841 tcaacattgc tgttcctacg agtacccaac tgaaaatagc tgggccgcca gccgatccgg
    21901 agatgtccgt cataatacca aatacgccac ctccaatcgc tgaaccaatt actaaggcag
    21961 caagtggaat taaaccaatt ccttttttct gttgctctgt atccatgtaa gcatcctcca
    22021 aaataaaacc gcttttatca aaaagtataa caaacctttt ttatttttac ttaattaata
    22081 aaaactttaa tagaaatata attctaccgg cttttttctc attatacaag caaagcgcct
    22141 agtccctttc caaattacac caccaaaaaa cttaaaaaag atgctatact aaaaggaaag
    22201 aattggagga tgatccatga acattttata tatatcgatt tcaggaaata cgcgtgcctt
    22261 tgccaaacat ctagcagaat atgctgaaaa aatgcatgca gaagatcctg tcaatcctga
    22321 agttacttta aaagaaatcc atgaaaatag tgattttacg aaagaaacag aaccattttt
    22381 tactttcgtt cctacttatt tagacggcgg aaatggttta gataacggtg atacagaaat
    22441 cttgaccgaa acgatgcgtg aatatctgga acatgaagac aatcataaac tttgtcttgg
    22501 tgtagtcggt agcggaaata aaaacttcaa taatcagtat tgtctaacag ccaaacaata
    22561 tgcacaaaca tttggctttc ctttcttggc agattatgaa ttacggggaa caccatctga
    22621 tgtgacacga atttatcaga ttttagcaga aaacaataaa taataaaaaa gaagaagctg
    22681 aaaaatagat ttcagtttct tctttcgttt ctattgtttc tatcatatta agctttgaca
    22741 tccatcacag gtgcttttgc ttttgcttta cctgtttttt ccaagacaaa gttttttaca
    22801 cgatccatat tggttaccaa gacgatcatg gatgtttctt tgcctgctgc tttgatcgct
    22861 tctaagtcag cttctgctac aagcgtatca ggtgtcactt gctgcccttc tgttactttc
    22921 acatcaaatg gcgtaccgcc taagtcaact gtgttgattc ccatatgaag caagatttct
    22981 aaaccatttg gcgttgtgat cccaatagcg tgtttcgttg ggaagacaga gctgactacc
    23041 ccagtaactg gagaatagat atgtccgttt tctggttcta caaagtagcc ttcacccatc
    23101 atcttttgtg caaaaactgg atcacttgct ttatctaaag aaacaactgt tccgtcagca
    23161 actgatgaga ggatagtcac actttcagct gaagtttgag gtactacttt ttcaggcact
    23221 tcatttactg tggctgtttc agtcgctaat tcttcttttt ctaaacggtc tttaggaata
    23281 ccgaagaaga atgtagcaac gaagccacca gcataagctg ccaataatcc aaggatgtag
    23341 cctaaccatt taccgtcaga gatcaatggg atcaaagcgg ctcctgaagg tccaatagcg
    23401 atagccccga catttccgat cattccgatc actgccccgc cgatacctcc accgatacaa
    23461 gcagtaataa atgggcgtcc tagaggtaat gttactccgt aaatcaatgg ttcgccgatt
    23521 cctaggatcc cgactggtaa agctcctttg atcatttctg ttaattcttt atcttttttg
    23581 cagcgaatcc ataatgccaa tgctgcaccc acttgtcctg caccagccat cgcaagaatt
    23641 ggaagcaata gcgtacgacc agtttcatca atcatttgca catggattgg agtcaaaatt
    23701 tgatgcagtc cgaacataac catcggcaag aataatgtgc ctagaacgaa gccggcaaat
    23761 gctccaccaa cgccaagtac ccagttgatc ccaccgacca tgccatcaga aatgaaacct
    23821 gctaaaggca tgatgaagaa aatttcaatc agaccgatgg caatcaatga aagagttggt
    23881 gtaacgatga tatctaccgc atcaggtact actttatgca gttttttctc aacgattgac
    23941 aatagccaaa cagcgaagat gacacctagg atcccacctt gtccagctgc aagagcttca
    24001 ccagtaaata agtttttcag tggtgcttcc ggattcatcc ctgtcagcat cacaacggcc
    24061 ccgataactc caccaagagt tggtgttgca ccaaaaactt gtgcagcatt gatacctgta
    24121 tagataacta ggtagctaaa catcccgttt ttcaagatgt tcatcacatc gatatattgt
    24181 tgccatgttg ctgcatcaag tgttccggct gtgactaagt ttgctaaaac tgcggcaatc
    24241 cctgccacga tcccagtacc gacaaatgca ggaatcattg gcacaaagat attagaaatg
    24301 tcttttaata ccgatttgat tttagatggt ttttgtttcg atttttgtgc cgctttcatt
    24361 tcttgtgccc gttcgtttac acggtctttt ccagatgctg atgaatttgc tgtagctgta
    24421 cttacagaag aaagtttttc tcctaatttc acgcctgcca aatcaaccat ttgctgtgct
    24481 actttgttca ctttcccagg tccgatgatg acttgaagct gttcatcttc tactacacca
    24541 agcactcctg gaatcgcttt taattcagag acatttacaa gatcatcatt gatgatcttc
    24601 atacgcacac gagtcatgca gtggacaatg ctttctacat tgcccatgcc gcctgcccct
    24661 ttataaattt gttttgccag ttcttccaaa gtcagttcgt tttttgccat ggtcttttcc
    24721 ccctcataag gtccctttta caaatccgtt tgcttcagct aattttgctt gagcttcctc
    24781 tttatcacta tttgtcaaaa tcatgacgat agccagctta acattttgat ctgcttcttc
    24841 aaagtacttt tcagctgttt cgtaatcagc ttctgtcgct tgcatgatga ttcgttttga
    24901 gcgttcgatt agtttttcat ttgttggttt gacatcgacc atcaagttat tgaatacttt
    24961 acctatacca atcatactga tagtagaaat catattcaag ataagttttt gtgctgttcc
    25021 tgacttcaat cgagtagagc ctgtcaaaaa ttctggacct gcatcgactt cgattgggaa
    25081 atccgcgtgt ttactgattt cggcttgttt attgcaagaa atcgttcctg tgacagcacc
    25141 gatcgatttt gcgtaatcta atccaccgat cacatatggt gtacgaccgc tagctgcgat
    25201 accaataact atatcatttt ttgtcaaatt cagcttgatt agatcttctt gccctagctc
    25261 ataagaatct tcggcccctt cgacagctac agtcattgct tcttctccac cagcaattag
    25321 acctatgacc atttccggtt ctacaccgaa tgtcggtacg cattcagcag catctaacac
    25381 acctagtctt ccacttgttc cggctcccat ataaatcaga cgtccacctt ttttaaagga
    25441 ctcaatcgtg ttagcaatca ctggttcgat acttgtcagt tctttttcaa ccgcagcggc
    25501 cactttctga tcttctttgt tcattagttg aacggcttga gaaatactca tctcatctaa
    25561 tccaaaagtt tcttggtttc tgcgttccgt tgttaggttc tctaaattga ttttgctcat
    25621 ttttatcttc cttcttttct tataaattga tagttcatac cagctttgat ttggttgatc
    25681 aatggtagct cttctttgat aactttagct actacattca ctttttcatc cgctggcaaa
    25741 tcatatttgg ttaattggat ctcacccata tagcgcaaat acttttcgtt atctaaagta
    25801 atagaccctt tcatacgcgt agctgtattt cttgctggga taggcggaat ctctcgaaaa
    25861 cgtgcatcta cgcttcgtat gacatctctt gcatcgtctt gccgattcgt atgcttccct
    25921 aatatatatt cgtaaaattc ttcatctaca ggttccgtat ggagcaagac tgtctgttct
    25981 ttttggaaag aagcaaattg ctcctgaacg ttttctgaca gacctgcatc tccgatgtaa
    26041 acaatatccg tgttacttgc taatagatct agagcgcctg caagaggatg gatccctcga
    26101 tgttcttcca aagttggcaa tccttgatat agtgggcctc tcaactctgt atctcctggt
    26161 acaaaacctt ggacaaggag accttgaatt ttgagccatt gatttttttt ctgataccat
    26221 tctttgtcca gccctgtttc gggacgtgga taataattat gccaagcttc aatctgtgag
    26281 aaatcagctt ctgcttcttt caattcatcg atatctttag gcgtgatcgt gctagcattc
    26341 aaactgattt tcaattgatg tgaccagtcg gcaatctgct gattggaaat atgataatcc
    26401 attcttaaac ctgttacacc aattgctttc aaaggcgtta gatcttctaa tgaaaaaccc
    26461 gctcgttcca atgcctctcc tgaaatatcg accatcaatt ctagtttatt ctttttcgct
    26521 tcgcttccta gttcgatcaa tcgcttttga tatgccgaaa catcatcttc tggtatatgc
    26581 atggaagtga aaataccgac aaagccattg gatgccattt ggcggatata ctgtttcttc
    26641 tcttctgaca aagaatcgtt cataaatatt gaaaagccaa acatattatc cctctttttc
    26701 tgtatccgtc ttcatttcta tgactagagt atatatctaa agaaacaaaa tttcaatact
    26761 tttattaaaa taattaaatt tcatttctaa aggttgagtt tatattatca aaagaattgt
    26821 cataacctaa aaaaggcact gctaagcaaa agcagtgcct tgaaatattt tatttaaata
    26881 acacaaaaac ataattactc ataagaaacc aattctgtat tatctaccat gaatgtaaag
    26941 aacccctcat taggcatcgg atgaaaataa gcattgatca ctcttatcaa ggcattatgg
    27001 caaactaaca gatagacatt ttcttcgtct tcgatgcatt ctttcaataa aggaacgatc
    27061 cgtgcataca catctaagac tgactcccca tttgggaatc gtacagcgaa cgctaaacgt
    27121 gctttttgaa agttctcatc tttgcttggc agtccatcat aatccccaaa atccatttct
    27181 accaatcgtt catcaacggt cagcggcaag ctgagacgat cagcaactgc ttgtgctgta
    27241 tctcttgctc gttgaagagg ggaatggatg attttcgtga ttggaacagg caaatctact
    27301 accttttctg ctagtttctg tgcctgcatc tgtccttttt cagtcagcgg cacatctgcc
    27361 cgtccgcaaa ctaatccttg tgcgttccaa gttgtttctc cgtgtctcgt tacataaagc
    27421 atgtgattct ctccttcgtt ggcaaagttc cccttaacca taccttgttg ttcttgagat
    27481 tacaagggtt agattctctc aagagaaata atctcagtag atactttatc caggaaggtt
    27541 tgatcatgtt ccactagtaa catggcaggt ttcacgttca agatcagttg ttctaattgt
    27601 tcttgattga agacatccaa ataattcaat ggttcatccc atgtatatag ttcagctggc
    27661 tgtgataaag atttagccaa ttccactttt ttccgttggc ccatactcat ctgctcgatc
    27721 ttgttatgaa aaacatctct ttccatccca agctttcgga ggttgttcaa aaatgcttgg
    27781 tagtctactt ggtttttctc tgcaaattcc gccaacgttc ctcgattgtc ttcataattt
    27841 tggcttgcat aactaatgct cagatgtttt ggctggtatt tttctcctat aaccttgccg
    27901 ttgaatgccc ccagaagata atggataatg gatgactttc ctgcaccgtt aggacctgaa
    27961 atcgccaccc gctgatgagg ctcgattgta aaatgaattg gctcgaataa cagattttca
    28021 taccctaatt gaagatcttc tacgcttaaa agtcgcttat ggtgagacgc ttggctattc
    28081 atcgtcaaag aatcgatata ttcgatatct tttaatagtt tttctttctc gctgatctgg
    28141 gtctccatcc gattcacgat tgctttggat cgtttcatcg tccgtgcagc atcagcaccc
    28201 actgctcctt tattcactcg tctagattca gtatcgatga atccgacttg tttctttgtt
    28261 ttatctcctt ctcgggaacg agaccattcg gctttttcag ctgctgtttt ctttagccta
    28321 ctgacttctt ttttcaattt ttcattttga gccatttcaa attcatcacg aagttttttc
    28381 tgttcttcat agatagagaa attcccttga taaagttcca gttgactttt ttcgattgct
    28441 aaaacatggt ccactacttc atcgataaat ccccggtcat ggctgaccac gatgaagcct
    28501 tgttttttct ttttcaaata agccgctact tgttttctac cagagatatc caaatgattc
    28561 gttggttcat cgattaacgg gaaatgagtg tcatccacaa ataaaagtgc cagtaggact
    28621 tttgtcttct ctccccccga tagtgtgctg aattctctcc ataagatttc aggatctgtt
    28681 tgcatcaatt ggagctctct ttcgatttcc catatctcaa aatccgtaat atcatttaac
    28741 acgtaatagg ttaaacgttc tttatctttt gtctgttgcg ggaaataggc aaattcttgc
    28801 tgatggatta cttgcccttg ataaggtagt ttgttttgta gaatattcag taaagttgtc
    28861 tttcctcgac cgtttcgtcc gataagtcct agtttccatt gtgtgtcaaa atttagattt
    28921 gcttgttcaa ataataatgt gccttggctg tcgtagccga atgtcagatt ttttatttcg
    28981 attttagaca ttttccatca cctcgtaaaa aaagaccagt cctattttca gaactggcta
    29041 aagaggatgc aagggttgga tacacacaaa aagacccata catcgaaaaa accaagccaa
    29101 tcccgaaaat ctgcacactg cttccttgtc tccacaaggt acagtctgaa tgcagctttc
    29161 atcaatcgac ttaatttttc aatgcacgga tccctcactt tgtcctatat ttgaaattac
    29221 gatagcataa agaaaatgat tttgtcaact acttcgggag gatggtgaaa aatctgctaa
    29281 gtgtctgtcc taagattttt gttttttcta atgtttgcct gtgttccatt gcttcttcta
    29341 aacctattgg acccaaatga atacttaaga caattgggag aaaatcagaa agtccttcta
    29401 gctcttggtc tctacttccg caaatagcga ttattggttt tcgatatttt tttgcaagca
    29461 ctgctacacc gtatggaact tttccgtgga tcgtttgctg atcgatccgc ccttctcctg
    29521 taatgatgac atctgcttgt tcgatctttt tttccaatcc agtgatttgg ctgactaaat
    29581 cgaaaccaga aaccatcttc gctcccaaca aaaaaagggc tccaccaata ccgcctgctg
    29641 ctccacttcc tggaatatca tctaaatcca cctcccagaa atcttttatt tgctgagcaa
    29701 tctttcctgc ttgtttatct aagaaagcta gcgtcgtatc tattcctcct ttttgtcttc
    29761 caaattgcca agcagctcct tgttgacctg tatatggatt ggtaacatct gcagcgataa
    29821 tcaattttac tttagaaaca agaacgtttc ttcgatcaaa atgaagtttt ttagtagata
    29881 ataaaggatt tccttctgtg tacccttcta aagaagcacc caaggattgg agtaatccta
    29941 gaccaccatc gctacacccg cttcctccta aagtgacaat aatttgttct acttcttgaa
    30001 gcagtgcatc tttaataagt tctcctaagg cataactgga agcaagtcgg atagtttgat
    30061 ccgttggttt atcaagtaga tctaacccca atgcttgtgc agattcgatg actgcggtgt
    30121 tttttccttg ccaagttgtc aataaatagc tgatttttcg ctgacggaat aagagatcca
    30181 tcccatcaat ggtacgccat gttcccctga gcgcgtaata gattgcttct gcagtatttt
    30241 ctccgccatc tgcaatcggc acattgattt ttcttccttt acgatcttcc cagccattta
    30301 gaactgcctg atttagttca aatgaagaag cacttccttt aaatgaatca attgccgcca
    30361 aaatatccat ctgtatccct cactttcttc ttaagtaaga cacttttttt catttttttc
    30421 aaacaaaaca atgctatttt cttccatttt tctatatact aaaagggaac tcattgaata
    30481 aaggagagaa aaaacatgaa aatcgcaata gctggggccg gagcaatggg cagccgaatc
    30541 ggattgatgc tacatcaaag cggaaatgag gtcctcttga tcgatcgttg gcctgctcac
    30601 attgaagcca ttcgtacaaa tgggttgatt gctgacttta acggtaaaga agtggtcgca
    30661 aaactgccaa tctattcacc agaagaaatc atcgaaagca acgaacacgt ggacttgatc
    30721 gtagcattaa caaaagccaa tcaattagat gatatgtttt gttcgatcca atccattatt
    30781 actgacaata cttatgtttt gtgtttacta aatggattag gtcatgaaga tgtactggaa
    30841 aaatatgtgc caaagaaaaa tatcttattt gggatcacga tgtggacagc tggtctagct
    30901 ggtcccggaa aagtcacatt gttaggtgat ggagaaatcg aactagagaa cttggaacca
    30961 gaaggcgaag catttacaaa aaaagttgta gaagtctttc aagaagcaaa tttaaatccg
    31021 atctatagcc ataacgttcg ttattccatt tggcgaaaag cttgtgtaaa tggaacattg
    31081 aatggtttat gcacgatttt ggattgtaat attgctgaac taggcgcgca aaaagcggca
    31141 gagagcatgg ttcgaacaat cgtatctgaa tttgcttcta tcgcagcaaa agaaggaatc
    31201 atactagatc aagaagaagt gtaccaacat attgcttcta cttatgatcc tgacaacatc
    31261 gggttgcatt acccatctat gtaccaagac ctgatcaaaa accatcgttt gactgaaatc
    31321 gactacatca atggtgccat ttggcgaaaa ggacaaaaat atgatattgc tacaccatat
    31381 tgtgcctttt tgacccaatt agtccatgca aaagaaggaa tccttggcgc agaataaaag
    31441 gctctctgat gagaatcagc tgaatcagca gctggttctc tttttttaag cccaataaaa
    31501 gatcaaaaag aaaacacaac tctcatgatg ccataagaat tgtgcttgtt tgtttcagta
    31561 cataatctct tcaaaatgta ggttttttat ttgttttcaa cagaggagag gtcatattcg
    31621 tattgctcat aaatagtgga atcgttagtg ataaatcgtt ttgcccaatt ttctgcatca
    31681 taaaattcca atagctctga taggattggc ttaaatggtg tatgcagaaa ttccggtaat
    31741 tcatctaaat cacgttctcg aagcaaaaaa atattttcag gacgataaaa atgataatga
    31801 gcaatcgctt gattatccgt cactagtttc ttttgaaaat acatggattc aaatgtccgc
    31861 aaagtcactc cttgctgacc ctcccgcaac agttccagaa tcccgcgcga ttcccctgtt
    31921 tttttcaggt actcttcata agtaagatat ccaggttgtt cattccctcg atgtggaaga
    31981 atgaaatagt tggtcgtaac atctcttttt ataaattcct gcttatagct ttctgctcgt
    32041 tcttttctcc cattattcgt tgcaccaaaa aatagatccg tctttggttc gctagaagaa
    32101 aaattcatat gtttcgaata aaatgaacta ttatgtttca gcccaagttc ttttgcttcc
    32161 aaaaaatcaa aatgataaat ctcatcgatt gccggttcat cttgtgcctg cttcagcatc
    32221 gcctcgtgtt ctgctttgaa gtgattccaa aaaaataaca caatttttgc attggtaaat
    32281 gggcgcacgc gtcgagccat ctccatatca aatccataat ctaaaaaaac gatcagctga
    32341 taatttgcca actgttgtct agctgattta atgaattccg actgtagtaa atcttttccg
    32401 gaccaaacat ctaaagagcg gatggaaggc aaaaaataaa gtgatttatt ttttgcaact
    32461 agcagtacgt catttttgtt catcttttcc gcctcacttt ctctgtcact ttttcctatg
    32521 atagcctgtt taaatagtaa aaagccagta aaacgtttcc tatatttgta tgaaaattta
    32581 acatttgtat gaaaatatga tgaaataaat cattcttcta ttaaaattcg cctaaaagtt
    32641 ttctgaatag ttgtaattgt ctgaaaattt gttatcatta gtcattgtta aatattgcta
    32701 tttattctta atataaattt tgattgtgaa tttaaaagaa agaggtcatt tatggaagat
    32761 aaaaaattga aaaaacaact tagctccaga catatcacca tgttagcttt aggtggagca
    32821 atcggtgcag gtctatttaa aggaagtggc gaagcgattg ggatcgccgg cccttctgta
    32881 ttgattgctt ttttgattgg tgggctgatt ttatatatcg tgatgaaagg tctgggaaaa
    32941 atcgttttaa gcggtggcga cacgcatcac ggattatctg gtttgatacg cccttatcta
    33001 ggtgctcatt ctgctgattt tactgattgg gtctactggt ctatgtggat tatcaatatc
    33061 atcgctgaag ctgttgcagc tgcttccttt ttgcagttgt ggttcccgca cattccagcc
    33121 tgggtatttg tttttatgtt ggctgtttta actacgatca tcaatcttta ttcggtacgg
    33181 ttattcgcag aaacagaata ttggctggct tttgctaaaa tcagtgtcat tatcttactg
    33241 atcatttttg ctacttatct tgtcggtcag caaatgttgg gcacaggcgt tttccctacc
    33301 cttcagcaat tgactgacca tggtgggttt actcctcatg gtatgaaggg aatcatcagt
    33361 tctttgcttg tagttatcta ttcttacggc ggttctgaac tgattgctat cacggtaagc
    33421 gaagcagatg atcctaaacg tgcgattcct aaagcaatca aaggtgtcat gggaagaatc
    33481 atttcctttt acatcattcc tttgtttttg cttttgattc tttttccttg gaatacttta
    33541 gcaggcacga atgtcagtcc ttttgtgatg gtatttgaaa aaatgaatat cccatttgca
    33601 gcggatatcg tcaattttgt gattgtcctt gctttgttct catctatcaa ttcgggtgtg
    33661 tatgcatctt caagaatttt gttcttccgt ttgaaggatc gaaaaggttc ctctagaaaa
    33721 ctagctgttt taaacaagca tcaagtaccg caacgtgctg ttttattttg taccagtgtt
    33781 ctttatcttg gtgtagctct ttcttatttt gtcggtgaca aattatttgg ctatctggca
    33841 ggttcccttt cgtatacagt attattgatc tggatcatta tcagtgcggc atcctttgta
    33901 ctggcactaa gaaaaggaac attatgggat aaaggaatca gcttttttgc attagctgtc
    33961 ttaggattga ttttccttgg tatcctgttc acgaactcca ttggggtaac tgtattgact
    34021 ggcctgcttt acctgttcat ttatttcagt tatcaaaaaa agaatgatgc gttcgtattg
    34081 acgaatgaat gaaatcgata gaaaatttta ttttatttat gtggaataga tggagctatt
    34141 gaagaaagga gttgtgacaa aagtcttgtt gcaactcctt tttccgaata aacagtctca
    34201 tgacctcttg gtaaacggtg ttcaaaaacc ctctgtgcaa aataattgat tgttctccat
    34261 gctcatgaca tgatagaaga aaggaatgaa aaaaaggagt ttgttttaaa tgaaaaagta
    34321 ttggaagttt ttgttgatga tcggtgtttc aacggtagtt atgtttggta tgatgtactt
    34381 gaatgtctat gcgctcgatc atatcttctt cagtcgtaca cgagtattca tggcgttgat
    34441 gatgggtgca gtcatggcag tcatcatgct gttgttcatg tggaaaatgt atgaaaacaa
    34501 aaagataaat gttatgatct tagccgctag tcttcttgtt tttgccggtt ccttgtttat
    34561 ggtacgaagc caaactactg tcaacgacac agcttggatg aaggccatga ttcctcatca
    34621 ttctatcgct atcctggcaa gtaaacgagc tgatttaaaa gatcctgaag taaaaaaatt
    34681 agcggaagaa atcattcagg cacaagaaga agagatcgac aaaatgaaaa aaatgatcaa
    34741 agaaatggaa tgaccattat ccgtccaaat aaaaaaagag gatgttccag aagttatcag
    34801 cttcaagaaa taagaagaag ctacttctgg aacgccgtga ataaggggtt gtgaaaaagc
    34861 tgccctgcat caagtaataa gaacagccaa acaaaaatag cttctcctat ttttcgtttg
    34921 gttaggctta ttaccgcaga tgcaagcttt tgaacaccgt ttattaagag gttgtaaaat
    34981 cagcgttctg acctgagtat tagagagaca aatggaaaaa tagttcctca tattttgcca
    35041 ttttttgagc taataccgag ggtcagctga ttgaacaccg tttatcgaga ggttgtgaaa
    35101 aagtcgctta gtttcgcgta ttaagaaaaa ttttgtgaaa tggctttcca catttttgta
    35161 taaatttggc ttaataccga gaaactggct tttgaatacc gtttattcgt aaaagggatt
    35221 gtgacaaaag tcttgtcaca atcccttttt atgtttttat tgttctaatt gcgctgtctt
    35281 gcttactgct tcttgcggtt tcacaaattt ttttgagatt ccccaacctg tgaaggcact
    35341 gaccatcgaa aacacaggag aaagcaaact gaaaaatacg aatggcaagt aagtgagtgt
    35401 aggaatacca aatgtacttg ctacgaaact tccggcaatt ccccaaggca ctaagtagtt
    35461 gattactgtt ccaccatctt ctagcgttct acctaataca gttggatcaa atcctgcttt
    35521 ttcataagtt tctttaaatg cattaccagg cagaataaca gataggaatt gttcaccaat
    35581 aaaaatattt actccgatac ttgtcatcaa tgttgtaaaa atcaaatttg gtgtgttcgt
    35641 catctttctt gatactcgtt ccatcacggt tgagatcaag ccaaattcga tcaacaatcc
    35701 acctaatgac aaagttagaa taatcaatga cacagtaggc atcatacttt cgattcctcc
    35761 gcggctaagc agtgaatcga tttgttggtt tccagtattt gaaacaaacc ctgattcgat
    35821 gaccccagcc aacttcgtta aggaagtttg tgggttttga ataaaaatca ttcctactgc
    35881 tacagcgata ttcaacaaaa tcgttaaaat tgccggcacc tttttccatg cacacagtaa
    35941 cattaaaaat aaaggaatca gtgaccagat tgaaatagta aagtttgctt ctagaacatc
    36001 agtcacttca cgaatagatg aaagacttgc ggctttactt gtgtgtccta aaatcatgaa
    36061 taaaaagaaa gaaacaacaa atgccgggac agttgaccac atcatatgct tgatgtgttt
    36121 gaacaaatcg gcatcaacaa tagctgctgc tagatttgtt gattcggata atggagacat
    36181 cttatctcca aaaacggcac ctgaaacaat agctccaaca accagcgctg gatttaagcc
    36241 tagtgttgtc ccaataccga aaaatgcaat cccaatcgtt gacataacag taaaggcact
    36301 ccctacagcg ctacctacga ttgcacacac aacaaataca gaagggacaa accactggac
    36361 actgatcaat ttgaacccaa tgaccattag agttggaatg atccctgctt gtatccatac
    36421 agcaatcaat gaaccgacta aaataaaaat aaagattggg atgattcctg gtttgatgcc
    36481 attgatgatt ccttcgtgca gccaatctgt cgggtatctt tttatcactg catacaacat
    36541 gaccattccg atcgctgcta agatcgtgat attaggtgag acctttaatc cgacaacgcc
    36601 aatcgcaatg cctaaaacaa taaccattaa tacaagtgtt gcttctaaaa aacttggtgt
    36661 tccttttttt cccatgataa tctctccttt tttagttgtt cttatgttct aaaaaagtta
    36721 agatatcgga ttactccgcc gcaattcatc cgcgattcct cctttataaa aataaaaaga
    36781 cctgttttaa actaaggacg aatgactccg cggtaccacc ttaattaaaa acagatctgt
    36841 ttttcacttt caaactttta ttcaaatgta tggactttcc atgtaattcg tcaattaggc
    36901 ttgatcggtt cacagcgacc accgactttc tgaacaaaac acctaaccgc tactgcgtga
    36961 aaagttgact tgtacgaagt ttaccttcca taagatcatt tgtcaatgaa aaagaaaata
    37021 ttttttcatt tttctgaaaa ttatttttat aactttcaca cacaagatta ttttttacta
    37081 gaaagtagcg ccctcttgtt tttttcttgc tactatttct tgatgttctt gcttgattct
    37141 ttctaatagc tttggctctt tcaacagatc aagagctgta ttggcgagta gttctgctgc
    37201 aatcgcaata gaagcaaggc ctttgtcact tttagcagca gctttgaatt cttctgtgtg
    37261 tccggcaata tatgtctcag agattgctac cgtaggctgg attgttggta tgacttggct
    37321 gacatttcct acatcagaag aaccgagact tgttctttgt tccgtttcta tttcttcatc
    37381 tggaacacct gcttcttttg catgctggaa gaataagtca tcaaaagaag gagtaacgat
    37441 gacatcatca actgcatttt ggaacaatcc aaactcaaaa gtcgtgcccg tacttatcgc
    37501 agcacctcgt acgatatttt ccactttttc atatacttta tctaatgttt gccgatttcc
    37561 tgcacgtaaa tagaaacgtc cagcagcgta atctggaatg acgttggcag ctactcctcc
    37621 gtctgtaatg atcccatgga tattgacatc ttttggcaat tgcaagcgta gagcgttgat
    37681 tccattaaac acttggatca atgcttccaa agcatttact cctttttcag gtgctgctgc
    37741 tgcatgggaa gcgacaccgt aaaatttgat gtcgactgga tcattcgcta aagattctgt
    37801 cgttttccca taacgaaaag ctggatggac gcataacgct acatcgacat cctcaaaaaa
    37861 accttctcga acaaagctgc ctttagctga tccgttctcg cccccttctt cccctggggt
    37921 gccatataca cggatttctc caccagtttc atcaatgaat tgcttcacta tgctggcggc
    37981 taatacggag taagtaccaa acaaattatg cccgcatgca tgaccaatac ctggtaaagc
    38041 atcgaattct gccaaaaagg caattgtggg accgggttta ttggaaatat aacgtgcatc
    38101 aaaggctgtt cggtgtccag ctacttcttt ttctacccaa aacctttctt tttctaattg
    38161 tttaatcaac gctgctgagg aataaaactc atagttactt acttcaggat gttcgtggat
    38221 atctagagca agtgcttgat attctggtaa acgatattgg attagatcct tcaattggtt
    38281 tgttgagatt gttgttgtca taaaaaattc ctcctatgct agtcattttt cttattttct
    38341 cccgaatgtt tcccatgcag gcacgcttga tccttttgat gttttctcga ttactttgac
    38401 tgtgtcttct gtttgataag cgtctactat tttttgatac gttttattgt tttcatcttc
    38461 ttttcttgca acgatgatat tcacataagg acgtgcatgg tcatccactg gttctaagaa
    38521 gatggcatca gaagcaggat taaatccagc atctacagct acaccgctat tgatcactga
    38581 aatgtctaca tctgacaaag cacgtgctgt ttgggaagca tctaattcag aaatgtctag
    38641 attttttcta ttctcggtaa tatcagaaac agtgggcgct tgtccttttg ccttatccac
    38701 tttgatcaat ccagcagttt gcaataacag aagagctctg ccgccatttg taacatcatt
    38761 agggattgct acttttgctc cgtctttgat atcagctaca tccttcaaag tgttagaata
    38821 aattcccagc ggtgcattga cagtatttcc gatcgatact aaatcagttc cgtgttcttt
    38881 attgtaattg tctaaaaaga attgatgttg gaaagaattc aaatcaatcg atccatctgc
    38941 taaagccaca tttggttgat tgtaatctgt aaatttcacg tattccaaat taatgttctc
    39001 ctttttcaaa cggtctttca cgttgtccca tacatctgta tcttctccaa taatccctag
    39061 ttttacgata gtttcttttt tgtcagttgt atctgctttt ccttggctac accctgccaa
    39121 ccaaataatt gctacaaatg taatgactac aaaacgaata atttttttca ttttttctcc
    39181 tccactttca atgtgtaatt tttttaatca gttgattact gataaattga cttaaaaaaa
    39241 ctaagattag aatcaataat gtagccacaa tcgttacatc tgtttggaat cgattatacc
    39301 ctctcgatat agcaagattc cctaatccgc ctgcacctac tgctccagcc atggtagtca
    39361 gtccgatcac gttgatgata gtcaacgccg agacccgaat gataccaggc aaaccttcta
    39421 acaaatacac acgtaaaatg ataccgattg gactggttcc catcgcttct gccgcttcga
    39481 tcaccccagg atcaacttct agcagtgcgt tctcgatttg acgagcaaaa aacggaacaa
    39541 ctccaaaaat caatggcact aaagctgctt tcgcaccaat cgtcgttcca actaagaaac
    39601 gagtagtcaa tgctaaaaga gaaagcaaga taatgaaagg gatggaacga atgatattga
    39661 tcagcttatc aagtatttca aatagcagac ggttagctag taatccatta gggcgtgtca
    39721 ctactaacgt cacacctaag atgattccaa tcatcccgcc aatgaatgct gtccaaaaag
    39781 acatatatag tgtttgcttc gtcgcttcga caaattcatc cggaatcaaa taaacattgg
    39841 gcaaatatgt tttaaagaaa tcagtcattt tatcttcctc cttcgatcac tttgatacga
    39901 ctatctaaat cgtttttttg taaaatattt atttttacac cagatttgat caaataatcc
    39961 aatgcttttt tccgctgttt ggtttctcca gctaaagtaa cgatcaaact ccctaacggc
    40021 gtttcttgta ataactctac attgccatat aaaatattcg ctgttacttg atatttgctg
    40081 tacagatgag cgattagagg ttcgttcgtc tgatttccaa tataacttaa ttccaccagc
    40141 catttattgg cgatctgatc ggcaaaagca gaatgggcaa tgatcgtttc taatgcttgg
    40201 tcaagatgag tagctgttcg aataaaatct ttggtcaatt cttcttcagg attgctgaag
    40261 atctggatgc tgctaccttt ttcaacgatt cttccatctt ccataaccgc taccttgttg
    40321 cagatttctt tgacaacttg catctcatga gtgatcagga cgattgttaa acctaactgg
    40381 cgattcaatt tttttaacaa tgcaaggatc tgaagggtcg ttttcggatc aagtgcactg
    40441 gttgcttcat cacataataa taccttaggt tcattcgcca aagctcgtgc gattgctact
    40501 cgttgttttt gtccccccga cagttgttta ggataagcag atgctttttc ttccaaaccg
    40561 acaagttcca gtagttcatt cactttttga cgacgttcct gtttcgattt tccagaatac
    40621 tttaaagaaa aatcaacgtt gtcaaaaata gttcggcttt ccattagatt gaaatgctga
    40681 aagatcatac cgatggcctt tctttctttt cgcaattctt tgggagagag ctgactcaga
    40741 ttcgtctgat tgacaatgac ttctcctgct gttggtttct gcagcaaatt catcacacga
    40801 actaacgtac ttttccctgc acctgagtaa ccgacgattc cataaacatc gcctttttca
    40861 atcgttaaat ctacagaatc tactgcctgt atctcttttt ctttttgttt gaaacataca
    40921 gaaacatctc gcaattcaat cattaaaatt cctccttatc taaaaaaagc gtcctcaaga
    40981 aaatgaaaat gtcattttct tgaggacgct tttttgcgtg ttaccacctc atgttcaagc
    41041 tgtgttcaca cacaactcct cttcaagtac gatcatactc tagcaagata tcggtcgcag
    41101 ccgtcatcgc cttacatcta tgctcgggat gaattgctcg atggccattt tccaatagtc
    41161 gttccttgct tcttctcagc taccgaagct ctctgtcaaa ggttcttcta tcgtacttac
    41221 catttcaatg caaataatat tcaaaaaaaa agtcctttta ctaacataaa ctatgtcagt
    41281 aaaaggacga cgtatcgcgg taccaccttt tttcggaagt ttccttccct caagcccaac
    41341 atctcaaaaa gagagattgg cgttcgtttt aacggtcgaa cagttccgaa tttgcctact
    41401 tatcgacaaa ttattctcca aggccatttt cagcttttct tacttgactc ttctcaccag
    41461 ccagagcctc tctgcaaagt ttccaaactt actttccttt tcaacgaaat cgatattttg
    41521 ttgttgggat taatctacat gaggaaaact gaaaagtcaa gtacgaaatt caaattattt
    41581 tttctatatt tatttttctg tttttttatt taacatttca ataacagttc gaagatcttt
    41641 tccttccgca agaagtttca atttttcctt ttcttcgacg gtataatttc ggacaaaact
    41701 ggaatcaggt atcaaaacaa cgcctaatcc tgctcgtgaa gcagctgttg ctcctactaa
    41761 agaatcttcc actgcaaagg ctgaactagc ttctaatcct gttcgttcca aagctgtcag
    41821 ataaggaatc ggtgaaggct tgttctccga cacttcgtct ccgaatgtaa acgtgtccaa
    41881 gtaatcagct aatttaaagt gatccaagat atctgttgct cttttcgtaa cagtggtcgt
    41941 agcaatgcct agtttcatat gacgttcttt taagtctgcc aatatttctt ttgcatatgg
    42001 ttttaagtgg atggctccgc ttgtcagctg ttgataaaaa tattcttcac gcttcgctcg
    42061 gacttcctgt actttttcag ggctacctgc tgctttcact aaaatatcaa aactttgttt
    42121 ccagtttttt ccgccccaag cgtcaacgat ttcttttggg atatggatat caaattgctg
    42181 aaatccccaa agccagccat cacgatacgt tttttctgtg tcaactaaca aaccatctaa
    42241 atcaaatatt gcacctttca tctatacatt aatcctttcc aaaacaatac acatagttta
    42301 gcacgactgg tccaaaaaga acagaagcaa agaaccagcc ttctcgttta taagagttct
    42361 tggaatcgac ggatatagat tttcttcaca gctgtcacaa gcgccagata agcgatgact
    42421 gtagcaaata accataacca gtaattgcca ggaagtggca tcaagcctaa ttcagcacca
    42481 aaacttgtaa aaggaaggac agaaccgaca ataattccta atgtagtgat aacaaacatg
    42541 gcaaatgttg cgttgctttg gataaatggt actttcggtg tacgcagtgc atggagcact
    42601 aaggtttgtg tccatagtga ttcgacaaac catcctgcat ggaataatgc gatgaaaatc
    42661 actcgctgtg aactatccaa tgtatggaaa cttccgccca ctacagcagg acaaataaca
    42721 aaatacatca acaagtaagt agtaatatca aatatcgaac ttgttggacc aaagtaaacc
    42781 atgaattccc caatactaga tgcattccat ttttttggct cgtccaaata ttctttatcc
    42841 atccgatccc atggcaagga aatgcaggaa acatcataga tcagattcaa aaacaaaagt
    42901 tgtaaaggca gcattggtaa aaatggcagg aacgtacttg caatcagcac ggaaaacata
    42961 ttgccaaaat tagaacttgc tgtagccttg atatatttca tgatattccc aaaagtttct
    43021 cgtccagaaa gaaggcctct ttccaaaatc gtcaaatctt tttctaaaag gatcacgtct
    43081 gcagattctt tcgcaatatc cacagctgta tctacagaaa taccgatatc agccactttc
    43141 attgcaggag cgtcattgat accatctcct aaaaatccga cagtatgacc atttttacgt
    43201 aaagctgtcg tcaaacgtgc tttttgctga ggattcaatt ttacgaatac ttcatggtct
    43261 tcagctactt gtgctaattc atgatcactc atttccgaga ttttctcacc ggtaaccaat
    43321 tcattgatct ctagacctac ttgacggcac actgaacgtg taactaattc gttgtcccca
    43381 gtcagaactt ttacagctac accatgttct ttcagagctt tcaacgcttg tttcgttgtt
    43441 tcttttggtg gatcaaggaa agcaagataa ccaatcaaaa ccatgtctga ctcatctttg
    43501 actgaaaatt ctccaacgac gcttggattg gtcttttgtg cgacaccaat cactcgtaag
    43561 ccatcttcat taagtgactg tacttttgca agtacggctt cttttcgttc ttttgttaat
    43621 ggtgtaacag taccgccaag atcaataaat ttagaaatgt tcagcatttc ttcaatcgca
    43681 ccttttgtga tcatttgtgt tttaccagct ggatcagcaa ccacaacact catacgacga
    43741 cgttcaaaat caaaaggaat ttcatccact ttttgataat tgatcttatc tgtatctaaa
    43801 gtttctgttg cttcatcaat gatagccaca tctaacaaat ttttcagccc tgtttgatag
    43861 tagctattta gatacgcatg gcgcaaaaca cgatcatctt catttccttc acaatccata
    43921 tgatattcaa gaatgatttt atcttgtgtc aatgtccccg ttttatccgt acataacaca
    43981 tcgattgcac caaagttctg gatggcattc aaatttttga tcactgttcc ttttttggcc
    44041 atcacacttg ctcctttgac caaattcgtc gtaacgatca ttggaagcat ttcaggtgtt
    44101 agaccaactg ctacagatag tccaaaaaga aaagcttcta gccaatcccc ttttgtaagc
    44161 ccattgatga cgataactgc tggagccatc aatgacataa atttgatcag tagcatggat
    44221 gttttatgga tgcctaattc aaagcttgat tgaattggtt tttcagatag cgtttctgct
    44281 acatgaccaa atagtgtttc atttccaaca gaaacaatga ttccttccgc acttccactg
    44341 atgacattac ttcccataaa gacaagattt tcgtaacttg tttcgctttg ctgatcgtct
    44401 tcacatactt tcgcatgctt ttctactgga tagctttccc ctgtcaatgc tgcttgggaa
    44461 atgaataaat cctttgcgga caataaacgc atatccgctg gtatcatatc ccctgctgaa
    44521 agccgaacaa gatctccaca gacgatttct tccataggaa tctctgtgta ctttccatta
    44581 cgttttacag ctgccgttac tttcacaagt gatttcagtt tttcagccgc ttgattggaa
    44641 cgtacggact gaatcaacgt cattgtcccg ctgacgataa ccatagtgaa gataatggct
    44701 acaccgaaaa gatctttatc tccaggagct gctaatacat attccgtgat gaatgaaata
    44761 attcctaatg cgatcaacac taatgtaaat ggcgtgatgt atgctttcaa tatttctaca
    44821 atgaatggtg tttttttgcc atatgaaatc gcattttcac cgtaattttc tcttgaacgt
    44881 tcgatttgtt cttctgtcaa tccatttgct gatgcatgga atagttcaaa taattcttgt
    44941 ttcgtttttc cagcaaaagc tgcatagatt ttttgtgtat ctttcttttt ttccatctca
    45001 atctctcctt tgtgtccaaa agacagctgt tctcgctgct tttggtcttt agctattcat
    45061 cggatcgata gagaaaaaac tgaaaggggc tgagaacaga tagataatag ccctggcctt
    45121 tcctctagat ccttgttttt cgaatgactg tcatccattt gttctcatct cctttactaa
    45181 gtaattttaa ttcatgactt ccaatcattt ttcgaatagt tatttttcca attagaccac
    45241 ctccttttta tttttcaccg atggggattt gcggcaacaa aaaaacctct cgccaaatac
    45301 tcagcgaaag gtttgaaaaa gcatattaaa aaaagcttct cagatctcat cgttgagttt
    45361 tgacactgta caacgtaaaa agcagatacc tgcttttagc taccttatga aaagccttat
    45421 ctcgacaatt cctgttctac ccattggcgt ctctcgacgt ttttgggcag tagcctatgt
    45481 ttgtatagga gcctcaccta acaaatctta ttcggttttc cttcgttaat ataacaacta
    45541 aaaaagagga tgtcaaatca attttccatg tttttcatac tttttttaaa atacacacgt
    45601 tatattcctg tctcacgcgg ttttatttgt ctcattttcc acctcccgct ataatagaaa
    45661 tatagtagga aacgaggtgc tgttatggaa agaacacttg ttattatcaa gccagacggc
    45721 gtgagacgcc atttagtcgg aagcatcatc caacgttttg aagcaaaggg actggccatt
    45781 gctgaaatga agtttgaaac tatgactcct gaattagcaa aagaacatta tcagcacttg
    45841 actgagcgca gtttttttga tgaactgatc gattacatga cttccggtcc tgtcgtttat
    45901 cttgtgctgg tcggcgagga agtgatcgat atcgtccgta agatggttgg agcaacaaaa
    45961 gctgccgatg ctgttccagg tacgatccga ggagactacg cgctgccggg gactgaaaac
    46021 atcattcacg cttctgattc ccgtgatgct gcggtaaaag agatcgcccg ctttttcccg
    46081 ccattcgata taaacaaacc gtctgaaaaa gcggcgaagt gatacaaatt ctaaactgct
    46141 ggtctagttg ctgggttcag caatggccag cagttttttc tctaaggacc tccgttgatt
    46201 ctttcctaac atatattcga gcactgtgaa gaattcttgg tagtctttcg tcttttcttc
    46261 ccctaaagca gcagaaatca atctttgata ataatctgcc atcaatgttt catagatcac
    46321 tgtacttctt tctttatgtg ctaagctccg tttcatatct tcattcacac tacgtgcctt
    46381 tttcaaccga ccattttcta tataaaacga agtcaggttc attaaaaaag taaagagata
    46441 ctgctcatga ttgttcaact gtgctaatcg tcgcattctt tttttgattt tcaaataatt
    46501 gttctcaatg aaccgatcac tgaatatcca aggaaaatca gctagaatag atagttcaaa
    46561 ttgaccatag tctggtatct gcatcaagta ttcttcaatg attcggcatt cataacgtaa
    46621 aaattcaaat tctgtctcag atacttctgt tttttcgacc atgtgaagat tcaaaaccaa
    46681 ataatacaga tcttctgttt tcttaaaatg cctacggtta ttgctgatct ctttataagg
    46741 atcaaagctg tcttcttgta cccgatctag cattcgtctt tttttcttta actttattgg
    46801 ttcatccagc tggtttcgca tccattcata ttctgcaagt gtcatgttca ttcgctctaa
    46861 aaatgatctc aatgttacaa atgacatttt tttcactgaa tttgtctcaa tcccgactag
    46921 agaagtctta aaacagattc cttccgctaa ttgggactgt gtcaacttct tgttgactcg
    46981 aagtttcttg atcaattcac catcatacat aatagttctc ctttttaatt taaatttttc
    47041 cacattcaat aaatagatac gttaaaaagg aaaaatacac gaaaaaaata aaaaaatgtt
    47101 tttttcataa aaaataccaa ccttcaagca ttagaatgtt gtctaactac tgaaggttgg
    47161 tttgattgtt tattgattat ttttttgctg ttcaacgtct gttcttgtta ctggatataa
    47221 gttggttgtt gttttattac cattttttga aaagacactt gtcgaatgtt cgcctttttg
    47281 cttttcgatt gcttcattac gttccgcttc atttttatag tcatattttt tcggatcaat
    47341 cgtctcaaat ccgtttggca cataaaaccg caagagattt tcctgattca gcttatctga
    47401 aagacttaac gcagtcttga ctttttcctg atctttggag atttcctcat cgattcctgc
    47461 tgctttcgta tcgatgattt ctcctgtctg attattgtaa gcttttcctc ctaggacggt
    47521 gtatttgggt gtcacaaagt tcccatttcg aaaagcaact acttgatcat gctgagaaga
    47581 taataagtct gtaccaaaat gaagataatc tttatcatcg attcccaata gatgtagtaa
    47641 tgtcggcaaa acatcgattt ctccaccgta ttcatgattg actgtccctt tagtataacc
    47701 aggcatatgg atcatcaatg gcactcgttg catctgtgcg ttgtcaaatt catcccatgt
    47761 atctggatct ttaccaagag cgcttgctaa atctttatta tctgtattcg agatcccaaa
    47821 atgatccccg taaatcacaa agattgaatt ttggtaaata ccagattttt tcaaatacgt
    47881 aaaaaattgt tccaatgatt gatccagata atgtgccgtt cgaacataat tatctactgt
    47941 gctattgcca gtattcaaag atggaaagtc gaaattcttg tcatccgtat aataaggcgt
    48001 gtggttggtt acggaaagaa atttcgtgta aaacggctgt tgtagatgct caagatattg
    48061 ggcagattct ctgaataaat ctttatctaa tatcccataa cctaacgttt cgtcggattc
    48121 atcaaaataa gatcgatcaa agaaattgtc ataacctaag tttttatata catgatctct
    48181 attccaaaaa ctagctacat tcccatggaa aacagcgctt gtatagcctt gcttttgtcc
    48241 aaggatcgct ggtgcggctt gaaagacatt gtctgaccca agttctgtga ataatgagcc
    48301 ttgaggtaaa ccaaatgtgc cagtttccaa catattttca gcatcacttg tctttccctg
    48361 tcctacttca tgaaagaaat tgtcaaagct gatcgttgct tgattctgga aaatactatt
    48421 taaaaacggt gtgacttctt gtccgtctac cttcatatta atcaaaaact gctggaaact
    48481 ttctaaatgg agaacgatca catttttccc tttagcgatc ccaaatgttt cgggatttgg
    48541 ctctgcataa tgtttctttg tataatctaa aacttcatca atcccattac tgcttgcatg
    48601 cgcgcgaaca ctgctagtca ttcctgtttt gattccgtca taaatagtat acgcatcgat
    48661 tcctagatat ttgacaatat atgaacggtc aaatgttcgc tgcagcaatt gtggacggtt
    48721 ggcttcgctc agcgctagat ttcctgaaaa aataagccct gaaagacagg taacagcgat
    48781 agccatcggt ttgccgacag ggttgctttt gataggtatt ttcttgacct tcaaccaaac
    48841 cagtagccca atgaacacag cgatatccag ccagtagatg acatcatggg gcttcatcaa
    48901 agaaaaggag cttcctgaca atccttgcga cactttcgaa aagcctaata cagatttgac
    48961 tgtaatgaaa tctgtgaatt cccgataaaa aataatattc aagtacaaca aaagcgtatt
    49021 taaaatatca atgatcaaaa gaatagctaa cgctggcttt ggctttttaa tatacaaaga
    49081 aaggccaaaa aacaataagg tagtcgcaat tgggttgatc cacaagataa agtactggat
    49141 cgtaccttcc acacctaatg aaaaatctgc atagtaggca atgatcgtct tcagccagaa
    49201 aaagaaaaca gctgtcaaaa cgattgctaa acgattttgg cacaattttt taagttgtgt
    49261 cacgtatatc acttctctct attcacattt tttcttattt tgctcctgaa aaatgaaaat
    49321 ttcctaaaaa agttgttatc ttaagatttt tttattcttt ctaaagatta ttccgtccac
    49381 ttttcacagc ataaaaccgc tgcgatgtaa gcgattaaac taatgaagag ataaaagtct
    49441 tgtggtgacc gcttcactcc acggtattca aaagccagtt tctcggtatt cgtacaaaaa
    49501 aagaggctgt gacaaaattc ttgtcgcagc tccttatttc ttgatgcagg acagcttttt
    49561 cacaacttct tccttaaacg gtgttctcct gccaactcct cggccacaag tcacaatatt
    49621 tataaaacat gagaagctgt tttttgaaat tgttccttgt ggctcagagt taaacggcag
    49681 gctcaagacc tcttgataca cggtgttcaa tcagctgacc ctcggtatta gattatgtca
    49741 ggacgctaat tttacaacct cttggtaaac ggtgttcaaa agcttgcatc tgcggtaata
    49801 agcccaacca aacgaaaaat ataaggagct attttttgaa attgctcctt gtggctcaga
    49861 gttaaacggc aggctcaaga cctcttgata cacggtgttc aatcagctga ccttcggtat
    49921 tagctcaaaa aacggcaaaa tatgaggaac tattttgccg tttgtttctc taatactcag
    49981 gtcaaaacgc tgatttcaca acctctgttt ttcattgtcc ataggattga tattgtcctt
    50041 gtgatgactc attcgtaata attgaggctt gattttcttc acttcccgtt atcgtttgtc
    50101 cactgccaga atctgaagga cttgttcctg tcgactcgtt tttttgagaa gagacagttg
    50161 ttttcttgac ttgttcattt gtctttttcc attccgctaa acgatcggcg accacttttt
    50221 tgtctacttt ttcagaataa gcggtgatca cttttccatt tttcaaacgg gctactttgt
    50281 cgccatcatg agtcaaaagc aaaacggtca aatgcttgtc tttaaattga tattgtctga
    50341 gagaaatcgc actaagtacg tcatcgatat taataaattg attttcttct tttccttttg
    50401 gcaaataaat gtccaattcg cctttttcgt aattggcagt tattttatac tccgcccacc
    50461 aataagttga gaattctttt ttgaaattat ctactgattc tttgcttgct acgatttttt
    50521 ctgtttcttt ctgagcaaga tctgctgtca tttttcctga aaatgctgcg gataaaataa
    50581 gcagtaagaa aaaaccgaat aaccaaaaga gaagaaacgg tctttttttc ctcatgcttt
    50641 cctccactcc tatttaattt tgactattct attatataca aaaaatgaaa tagaaagaca
    50701 aaaaagttga aaaagatcgt aaataattga acttcttttt cacaaaatgg taagaatgga
    50761 gaatttcacg catttgctct caactattct ttcttaagcc tcaaatccgt ttttatctga
    50821 tacgtctttg aaccaatgac ccgatttttt gattgttctt tttccatctt gtgctaagtc
    50881 tactgaaata aagccatatc gattcttata tgcattggtc cacgaccagt tatccataca
    50941 tgtccacata tgatagccta aacaattggc accttcttga atggcttgat ggacatattt
    51001 cagatgagat tggacaaatt cgatccgata atcatcgtgg atcatgccat cttctttgat
    51061 aaatcgtgct tcgttttcta cacccatacc gttttcagaa ataaagcagt cgatatttcc
    51121 ataatgatct cgtacattga tcaaaatatc atagattcct tgttcataga tctcccatcc
    51181 gcgataagga ttcattttac gaccaggcat ttcataattg tcgaaataat cctcaggcat
    51241 tggaccgttt ttagtatcga ttggtgtttc ttttgctttt acccggcgtg gctggtaata
    51301 attgatacct aaaagatcta ctgtattttc tttgataacc gtcaaatcct ctgcatggat
    51361 cacaggcatg agatcaagtt cttttactat ctcaatcaat tcacttggaa actcgccttt
    51421 tacagctgga tcaaggaatg aacgattgaa gaacgcatct gctatttgcg ctgctttaac
    51481 atcttcaggg tttgattcgt ctcttggata gcttggtgtc agattcaaga tgataccaat
    51541 aacaccacct tgctccattt catggtaaga tttgatggct aacgctgaag ccaacgcttc
    51601 atgatagcca acttggatcg cttttttcat atctgactct tctggataat gccatcgata
    51661 taaataacct gcttcgactg gaacgattgg ttcattatga gtaaaccatt tttttacttt
    51721 cgaaccaaac aattcaaaac aacttttggc atatttttca taggcttcaa ccgtttctcg
    51781 gttcaaccat ccgccttttt cttgcagata catcggcata tcgaaatgat acagattcac
    51841 aaagggttcg ataccgtttt caatcaactc atcaaaataa cgatgataga aacgaacggc
    51901 ttcttcgttg attgttccag attcatcagg tatcaaacgg ctccattgga tagatgttcg
    51961 aaatgaatta tgcccagtct gtttcatcaa ctgtacatcc tcttgatact tcgtataaac
    52021 ttgcgaggtt ttttcaggtc ctacttgatc aaagaacttt tgcggttctt ttttgtacca
    52081 ataatcaaaa atgttctctc cttttccatc gcctgaaatc cttccttctg tttgtgggcc
    52141 acttgctgca gaaccccacc aaaaatttgc tggaaattga tattttttca tcaaagcacc
    52201 tctttttctt ttttagttcg ttttagttga ttccatgtat gatattttcc atcacaatca
    52261 ctttttcatt ttcttcctct tcttttttga ttcgttttaa cagctgttct gctgctcgtt
    52321 ccccgatttt atctgttggt ggcgtgatcg tgattttcgg aaggatactc agatcgtttt
    52381 tatctaaata atcatagtga ctgaacgcaa tatccttccc gattctgaca ccttcttgat
    52441 tgaaacattc gatggcacca atcgacatat tgtaattgct gacaaaaata gcagttgccc
    52501 ctttttctaa taatgctttt gccccgtaat agccgctttt tctagaatag tctcctgtaa
    52561 agacctctaa ttggatcgat ggatcatttt ggaccgcttc tttggctcct gctaaacgtt
    52621 ctcttgctac gtagtctgtt tgagtggcag caataaatcc gattttttta tgtccttgtt
    52681 caccatgatg agcgatcact tttgctacac tttctcgatc attcactaat attgtatcaa
    52741 tacctgctgg tccttctgga caattcaatg cgataactgg aatactcatt tttgtgagca
    52801 tttcaaatcc agaccactct tcttcggata agaagacaat cagcccatcg atcacatgct
    52861 tcatcaggta ttcaattttt tgttcaattt tttctggctg atcggcaaac ccgcttaata
    52921 ataagctata cccattttct tcagctactc tttcgatccc tgagacaact tccgacccaa
    52981 aacggctgga aatcccgttt atcaaaagtc caatagagaa gcttcgatta ttcttcaacc
    53041 ctttagcaat gatgttttct ttatagtcca acgctgaaat cgcttctgct atttttttca
    53101 tgttcttttc cttcagttgc tgaccattca agtaacggga aactgttccc actgaaacac
    53161 cagccatctt agccacatca cggatcgatg ccatacattc tcactcctgc cagttacatt
    53221 tgatttctct ttcttgttgt tcgattatga tgaccgcatt ctttgcatag tgttgcttgt
    53281 catcaatatc catataacta aagtcttcag tagagcaact tcctctcact attaattata
    53341 cttaaacaag tatttgaacc ggttcatttt taatatagca tttttttaaa agattgcaac
    53401 acttttttaa aacgctttct gaaagtggcg gattttttgc ctttttaaaa ttttattcta
    53461 aaatttactc tatttgtggg tgttttgtgc gtttttctct tccatccgtt tgaagtttta
    53521 cattccaatg gtataatttc tttatcctat caaatggggg aagtattttg aagaaattaa
    53581 tcgtactatt tattttgtct gcgggacttt tgacattgac tggctgtgat ttgtttggcg
    53641 gctctgacca atcctcggac gaaacaaccg attcttctgt cttaaaagcg gaaaaagcag
    53701 ataccaccaa cagtgtatat acgctaaaag tacgtaaaga tatggattta tccgcgggac
    53761 agttgacatt tacagataaa aaaatggaat ggacacgcac gtatcagaca caaggaactg
    53821 attcttctga atcatctgaa gaaaaaacag tgctgacaga tatcaagatc actaccaaag
    53881 atgacgaata tattatttca ggaaaagaaa ataaaaaaga aacaacagtc atatttacaa
    53941 aaatcggtaa ttaccgtttg aaggatgagg atggcaacat ctacagtcta tagtgccgtc
    54001 tgttggatct tcttttgttt ctccccttct tttctgctat agtaaagaag caagatgatt
    54061 gtaaaggaga cgaaatggat gatcgatagt cctgattatt gtacatgtaa taacaacaaa
    54121 aatatccata cagaatttaa tgaccaagga agcttgagca tatgcgacaa ctgtcacaaa
    54181 ctagtcaaag attcatttaa aacatttgaa tcttatcctg ttcaaaatta tgtaaaaagt
    54241 agaagaagat aaacaaatcc aagcaaaact cactatggct gatttttatg aacttcaaac
    54301 tcagcttctt cctttgatca agcttcatca gtaaaacaaa cagtggatca tttcagttta
    54361 caaatcaaag agtaaagatt tatttatttc aaatatttga atataaaata accaaacgat
    54421 agaaaggctt attctacatc acgtagta
//
LOCUS       DAYYEF010000014        51371 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000014 DAYYEF010000000
VERSION     DAYYEF010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51371)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51371)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51371
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.014"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            149..1294
                     /gene="tgt"
                     /locus_tag="ACHA1B_000971"
     CDS             149..1294
                     /gene="tgt"
                     /locus_tag="ACHA1B_000971"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008479 - tRNA-guanosine(34) queuine
                     transglycosylase activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HFM8701752.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            1391..1771
                     /gene="yajC"
                     /locus_tag="ACHA1B_000972"
     CDS             1391..1771
                     /gene="yajC"
                     /locus_tag="ACHA1B_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HFM8701753.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            2075..4672
                     /gene="adhE"
                     /locus_tag="ACHA1B_000973"
                     /gene_synonym="adhC"
     CDS             2075..4672
                     /gene="adhE"
                     /locus_tag="ACHA1B_000973"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006066 - alcohol metabolic process
                     [Evidence IEA];
                     GO_process: GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HFM8701754.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            4901..6007
                     /locus_tag="ACHA1B_000974"
     CDS             4901..6007
                     /locus_tag="ACHA1B_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFM8701755.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            6024..7052
                     /locus_tag="ACHA1B_000975"
     CDS             6024..7052
                     /locus_tag="ACHA1B_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HFM8701756.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            7058..7537
                     /locus_tag="ACHA1B_000976"
     CDS             7058..7537
                     /locus_tag="ACHA1B_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HFM8701757.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            7553..8848
                     /locus_tag="ACHA1B_000977"
     CDS             7553..8848
                     /locus_tag="ACHA1B_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HFM8701758.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            8859..9683
                     /locus_tag="ACHA1B_000978"
     CDS             8859..9683
                     /locus_tag="ACHA1B_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFM8701759.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            9848..10747
                     /locus_tag="ACHA1B_000979"
     CDS             9848..10747
                     /locus_tag="ACHA1B_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8701760.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(10873..11742)
                     /locus_tag="ACHA1B_000980"
     CDS             complement(10873..11742)
                     /locus_tag="ACHA1B_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFM8701761.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            11895..13355
                     /gene="rhaB"
                     /locus_tag="ACHA1B_000981"
     CDS             11895..13355
                     /gene="rhaB"
                     /locus_tag="ACHA1B_000981"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008993 - rhamnulokinase activity
                     [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HFM8701762.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            13352..14608
                     /gene="rhaA"
                     /locus_tag="ACHA1B_000982"
     CDS             13352..14608
                     /gene="rhaA"
                     /locus_tag="ACHA1B_000982"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008740 - L-rhamnose isomerase activity
                     [Evidence IEA];
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HFM8701763.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            14622..15467
                     /gene="rhaD"
                     /locus_tag="ACHA1B_000983"
     CDS             14622..15467
                     /gene="rhaD"
                     /locus_tag="ACHA1B_000983"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008994 - rhamnulose-1-phosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019301 - rhamnose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HFM8701764.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            15469..15780
                     /gene="rhaM"
                     /locus_tag="ACHA1B_000984"
     CDS             15469..15780
                     /gene="rhaM"
                     /locus_tag="ACHA1B_000984"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0062192 - L-rhamnose mutarotase activity
                     [Evidence IEA];
                     GO_process: GO:0019299 - rhamnose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HFM8701765.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            15861..17012
                     /gene="fucO"
                     /locus_tag="ACHA1B_000985"
     CDS             15861..17012
                     /gene="fucO"
                     /locus_tag="ACHA1B_000985"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008912 - lactaldehyde reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HFM8701766.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            17139..17897
                     /locus_tag="ACHA1B_000986"
     CDS             17139..17897
                     /locus_tag="ACHA1B_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HFM8701767.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            17997..18641
                     /locus_tag="ACHA1B_000987"
     CDS             17997..18641
                     /locus_tag="ACHA1B_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HFM8701768.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            18648..19655
                     /locus_tag="ACHA1B_000988"
     CDS             18648..19655
                     /locus_tag="ACHA1B_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PfkB family carbohydrate kinase"
                     /protein_id="HFM8701769.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            19671..20513
                     /gene="kduI"
                     /locus_tag="ACHA1B_000989"
     CDS             19671..20513
                     /gene="kduI"
                     /locus_tag="ACHA1B_000989"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008697 -
                     4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0045490 - pectin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HFM8701770.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            20533..21336
                     /locus_tag="ACHA1B_000990"
     CDS             20533..21336
                     /locus_tag="ACHA1B_000990"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HFM8701771.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(21585..22649)
                     /gene="fni"
                     /locus_tag="ACHA1B_000991"
     CDS             complement(21585..22649)
                     /gene="fni"
                     /locus_tag="ACHA1B_000991"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HFM8701772.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(22646..23731)
                     /locus_tag="ACHA1B_000992"
     CDS             complement(22646..23731)
                     /locus_tag="ACHA1B_000992"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HFM8701773.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(23744..24721)
                     /gene="mvaD"
                     /locus_tag="ACHA1B_000993"
     CDS             complement(23744..24721)
                     /gene="mvaD"
                     /locus_tag="ACHA1B_000993"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HFM8701774.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(24714..25658)
                     /gene="mvk"
                     /locus_tag="ACHA1B_000994"
     CDS             complement(24714..25658)
                     /gene="mvk"
                     /locus_tag="ACHA1B_000994"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004496 - mevalonate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016126 - sterol biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HFM8701775.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            25974..26633
                     /locus_tag="ACHA1B_000995"
     CDS             25974..26633
                     /locus_tag="ACHA1B_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFM8701776.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            26718..27623
                     /locus_tag="ACHA1B_000996"
     CDS             26718..27623
                     /locus_tag="ACHA1B_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFM8701777.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(27625..28257)
                     /locus_tag="ACHA1B_000997"
     CDS             complement(27625..28257)
                     /locus_tag="ACHA1B_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFM8701778.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    28408..28533
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            28577..29101
                     /gene="infC"
                     /locus_tag="ACHA1B_000998"
     CDS             28577..29101
                     /gene="infC"
                     /locus_tag="ACHA1B_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003743 - translation initiation factor
                     activity [Evidence IEA];
                     GO_process: GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HFM8701779.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            29173..29373
                     /gene="rpmI"
                     /locus_tag="ACHA1B_000999"
     CDS             29173..29373
                     /gene="rpmI"
                     /locus_tag="ACHA1B_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HFM8701780.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            29426..29785
                     /gene="rplT"
                     /locus_tag="ACHA1B_001000"
     CDS             29426..29785
                     /gene="rplT"
                     /locus_tag="ACHA1B_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HFM8701781.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            30037..31374
                     /locus_tag="ACHA1B_001001"
     CDS             30037..31374
                     /locus_tag="ACHA1B_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HFM8701782.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            31422..33551
                     /locus_tag="ACHA1B_001002"
     CDS             31422..33551
                     /locus_tag="ACHA1B_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HFM8701783.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            33526..34215
                     /locus_tag="ACHA1B_001003"
     CDS             33526..34215
                     /locus_tag="ACHA1B_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701784.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(34623..35236)
                     /locus_tag="ACHA1B_001004"
                     /pseudo
     CDS             complement(34623..35236)
                     /locus_tag="ACHA1B_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(35372..35566)
                     /locus_tag="ACHA1B_001005"
     CDS             complement(35372..35566)
                     /locus_tag="ACHA1B_001005"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701785.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(35616..36056)
                     /locus_tag="ACHA1B_001006"
     CDS             complement(35616..36056)
                     /locus_tag="ACHA1B_001006"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HFM8701786.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(36060..36905)
                     /locus_tag="ACHA1B_001007"
     CDS             complement(36060..36905)
                     /locus_tag="ACHA1B_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016836 - hydro-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HFM8701787.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            37054..38472
                     /gene="pepV"
                     /locus_tag="ACHA1B_001008"
     CDS             37054..38472
                     /gene="pepV"
                     /locus_tag="ACHA1B_001008"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HFM8701788.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(38529..39476)
                     /locus_tag="ACHA1B_001009"
     CDS             complement(38529..39476)
                     /locus_tag="ACHA1B_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM8701789.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(39699..40049)
                     /locus_tag="ACHA1B_001010"
     CDS             complement(39699..40049)
                     /locus_tag="ACHA1B_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFM8701790.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            40249..41328
                     /gene="pepA"
                     /locus_tag="ACHA1B_001011"
     CDS             40249..41328
                     /gene="pepA"
                     /locus_tag="ACHA1B_001011"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HFM8701791.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            41472..41792
                     /locus_tag="ACHA1B_001012"
     CDS             41472..41792
                     /locus_tag="ACHA1B_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFM8701792.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            41814..42278
                     /locus_tag="ACHA1B_001013"
     CDS             41814..42278
                     /locus_tag="ACHA1B_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFM8701793.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            42483..43088
                     /gene="ytpR"
                     /locus_tag="ACHA1B_001014"
     CDS             42483..43088
                     /gene="ytpR"
                     /locus_tag="ACHA1B_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtpR family tRNA-binding protein"
                     /protein_id="HFM8701794.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(43127..44416)
                     /locus_tag="ACHA1B_001015"
     CDS             complement(43127..44416)
                     /locus_tag="ACHA1B_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HFM8701795.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            44844..45323
                     /gene="rlmH"
                     /locus_tag="ACHA1B_001016"
     CDS             44844..45323
                     /gene="rlmH"
                     /locus_tag="ACHA1B_001016"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HFM8701796.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            45408..45917
                     /locus_tag="ACHA1B_001017"
     CDS             45408..45917
                     /locus_tag="ACHA1B_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HFM8701797.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            46017..46667
                     /locus_tag="ACHA1B_001018"
     CDS             46017..46667
                     /locus_tag="ACHA1B_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701798.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            47118..48056
                     /locus_tag="ACHA1B_001019"
     CDS             47118..48056
                     /locus_tag="ACHA1B_001019"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFM8701799.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            48069..49121
                     /locus_tag="ACHA1B_001020"
     CDS             48069..49121
                     /locus_tag="ACHA1B_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFM8701800.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            49387..50022
                     /locus_tag="ACHA1B_001021"
     CDS             49387..50022
                     /locus_tag="ACHA1B_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFM8701801.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            50213..51004
                     /gene="msrA"
                     /locus_tag="ACHA1B_001022"
     CDS             50213..51004
                     /gene="msrA"
                     /locus_tag="ACHA1B_001022"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFM8701802.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
BASE COUNT        16367 a         9130 c        10987 g        14887 t
ORIGIN      
        1 tttctttttt ttgttattca taaaaaaagg ataaaaaaaa gaatattaaa taaagtagaa
       61 ggaagccgag ggaacttgca aaaagcactt gaaacgatta tgatggtggg agttgtcaag
      121 atattttata tagaaagtag ggaaatgaat gacgcaacct gccattcgct atcgtttaat
      181 caagaaagaa aaacatactg gcgcgcgttt aggggaattg atcacgccac acggaacttt
      241 ccccacacca atgttcatgc cagtaggaac attagctaca gtaaaaacaa tgtccccaga
      301 agagttgaaa gaaatgggtg ctggcgttat tttaagtaat acatatcatt tatggctacg
      361 ccctggtgaa gacttagtag aagaagctgg cggactgcat aaatttatga actgggatca
      421 accgatttta acagattcag gcggctttca agttttttca ttaagtgata tgcggaatat
      481 cgaagaagaa ggcgtgcatt tcaaaaatca cttgaacggt tcgcgtatgt ttttatcacc
      541 agaaaaagca atcaacatcc aaaataaatt gggctctgat atcatgatga gttttgacga
      601 atgtccacca ttcgatgaaa gttacgacta cgtgaaaaaa tcagtagaac gtacgtctcg
      661 atgggcagaa cgaggattga aagctcatgc taatccagac cgtcaaggat tatttggaat
      721 catccaagga gcagggtttg aagatcttcg tcgtcaaagc gcgaaagatc tagtcgggat
      781 ggatttccct ggttactcaa tcggcgggtt atctgtcggg gaacctaaat cagaaatgaa
      841 tcgtgtatta gaattcacta caccgttgat ccccgaaaac aaaccacgtt acttgatggg
      901 tgtcggtgct gctgattcat tgatcgatgg tgttatccgt ggagtagaca tgtttgactg
      961 tgtcttgcct actcgaatcg ctcgaaatgg cacatgtatg acttctcaag gccgtctagt
     1021 agtgaaaaat gcgaaatatg cccatgattt ccgtccaatt gatgagaaat gtgattgtta
     1081 tacatgtaaa aactatacac gtgcctatat ccgccatttg atcaaatgtg atgaaacatt
     1141 tgggattcgt ttgacttctt accacaattt atacttcttg ttgaatctaa tgaaacaagt
     1201 acgtcaagca atcatggatg ataatttgct tgaatttaga gaagcctttt ttgaagaata
     1261 cgggttcaat aaagaaaacg caaaaagctt ctaaaggaaa atcttttaaa aattaagtaa
     1321 aaaactagtg ttatcagcat ttttctgcta aagtgttttt tgtagataca gaattagtga
     1381 ggtgaaaaaa atgggaacat taccaatgct tgtgatgttt atcgcgctat tagcaatgtg
     1441 gttttttatg tcacgttcgc aaaagaaaca acagcaagaa cgtcaaaact tgttagatag
     1501 catgaaacca ggtgattcag tcgtaacgat cggcggatta catggagttg tttcagaaat
     1561 cgacaatgac aaacggacag ttgttttaga ctgcgaaggg atcttccttg agtacgatcg
     1621 tgcagcaatc aaaacggtca aaccagggac tgtcgtaaca aatgatgcaa cgactactgt
     1681 tgaaacaaca gaagaaccag ctgagacagt tgaagtaaaa actgaaacaa cagaaacgct
     1741 ggaagagaca gaagagaagg aagaaaaata agtatcaaag cttatttaaa gacgaggtag
     1801 ggcagaaaga tgtcctacct cattttttat tcaaaaaaga aagagataag agcatgggat
     1861 atattgctca atattgaata atcgggtgtg tcatataaat aataataaat aactttatat
     1921 atttttctat acaaacacct gtaaataaag caattttata tttaaaaata actgtgaaaa
     1981 aatcacaaaa aagtgtttac atagaaaaat aaatattgta tgatatacat gtgaattatt
     2041 taacaaataa ccatgaccca ttaggaggat aatgatggct aaagtaatag aaaaagaaaa
     2101 aacgaagaca attgacgtac aagcaatgat tgatgatttg gcagaaaaag caaatgcagc
     2161 attgaaagaa atggaaagct ttgatcaaga aaaagtagac catatcgtgc atgaaatggc
     2221 aatggcagct ttggatcaac atatgccatt agcgaagatg gctgtagagg aaacaggccg
     2281 cggtgtttac gaagataaag caatcaaaaa tatgtatgcg tccgaatata tttggcataa
     2341 tatcaaacat gataaaacag ttggtgtgat caatgaagat gtccaaaaag ggttgattga
     2401 aattgctgaa ccagtcggtg tggtttgcgg agtaactcca acaacgaatc cgacttccac
     2461 aacgattttc aaatcaatga tcgcgttgaa aacaagaaat ccaatcgttt ttgctttcca
     2521 tccaagtgcc caaaaatctt ctgcagaagc agcacgagtg gtacgtgatg ctgctatcgc
     2581 tgccggagct cctgaaaatt gtatccaatg gatcgaacat ccttcgatcg aagcgacttc
     2641 tatgctaatg aaccatccag gtatcgcgat cgtcttagcg acaggtggag ctggaatggt
     2701 caagtctgct tactctacag gaaaaccagc tttaggtgta ggtccaggta acgtaccagc
     2761 ttatattgaa aaaacagcaa aaattaaacg tgcagtgaac gatttgatcg tttcgaaaac
     2821 atttgataat ggaatgattt gtgcttctga acaagctgtg atcgtggata aagaaatcta
     2881 tgcagcagta aaagcagaat tccaagcaca ccaagtttat atcgtaaaac cagatgaatt
     2941 gcaaaaatta gaagatgcag tgatgaacga aggaaaatat gcggtcaatc catcaatcgt
     3001 tggacattct gcgatggaaa tcgcaaaatt ggcaggaatc agtgtaccaa aaggaacgaa
     3061 aatgctgatt gctgaattgg aaggcgtagg cccagattat ccgctatcaa gagaaaaact
     3121 ttctccagtt cttgccatga tcaaagctaa caacacggac catgcgtttg atttgtgtga
     3181 aggtatgttg aatcttggag gattaggaca tacagcagtt atccattcag aaaacgaaga
     3241 gttgcatgtc aaattcggtc ttcgaatgaa agcttgtcgt attttagtga atacaccatc
     3301 tgcagaaggc ggcatcggtg atatctataa cgaaatgatt ccgtcattga ctttgggatg
     3361 cggttcttat ggtaagaact ctgtttctcg taacgtctct gctgtaaact taatcaatgt
     3421 caaaactgta gcgaaacgga gaaataacat gcaatggttc aaattaccgc caaaaatctt
     3481 ctttgaaaag aactctctat tgtacttaga gaaaatggaa aacgttgaac gtgtcatgat
     3541 cgtttgtgac cctggtatgg tccaattcgg ttactgcgat acagttcgtg aagtattggc
     3601 acgacgtaaa aatgatgtga agatcgaagt cttctcagat gttgaaccga acccatcgac
     3661 aaataccgta tacgcaggaa cgaaactgat ggcagacttc aagccagata cagtaatcgc
     3721 tcttggaggc ggttctgcaa tggacgcagc taagggaatg tggatgttct atgaacaccc
     3781 agacacatct ttctttggtg caaaacaaaa attcttggat atccgtaaac ggacatataa
     3841 gatcgacaaa ccagaaaaaa cacaattcgt atgtatcccg acaacatcag ggactggttc
     3901 tgaagtaacg ccatttgcgg tcatcactga cagtgaaaca catgtgaaat atccgttagc
     3961 agattatgca ttgacgccag atgtcgcaat cgtcgatcct caattcgtca tgtcagttcc
     4021 agcatctgtc acagcagata ccgggatgga tgtgttaaca catgcaatcg aatcctatgt
     4081 ttcagtcatg gcttcagatt atacacgtgg attgagccta caagcaatca agttagtctt
     4141 tgactattta gaaaaatcag taaaaacacc tgatatggaa tcacgtgaaa aaatgcacaa
     4201 cgcttctaca atggctggta tggcgtttgc taacgcattc ctaggtattt gtcactcagt
     4261 cgcacataaa atcggcgggg aatacgggat ccctcatgga cggacaaatg cgattctttt
     4321 accgcatatt atccgctata atgcaaaaga tccacaaaaa catgcgatgt tccctaaata
     4381 tgactatttc cgtgcagata cagattacgc agatatcgca aaattcttag gtctgaaagg
     4441 cgaaacaaca gaggaattag tcgaagcttt agcaacggct gtttatgaat taggaaaatc
     4501 tgtcggcatc aacatgagtc taaaagctca aggagtcaca caagaaacac tagatacaac
     4561 cgtagaccgt atggctgaat tagcttacga agaccaatgt acgacagcta atccgaaaga
     4621 accattgatc tctgaattga aacagatcat cattgatgct tacaacggat aagcaaaaga
     4681 aagcgtagaa aaaagataag aaaatagatg aaaaagaact tggaaaacgt tgtttctcca
     4741 agttcttttt ttaatttcca agtaactgaa agttactttt gttatttaac atttaggtca
     4801 attttagaca gtttttgttc aaaaagcgat atttatagtg gacggtatta ctgctatatt
     4861 aaggatataa aatgaaagcg tttaaaaagg tggcgtaaag atgattatta aagaagagat
     4921 ttttgtacct aaagaattag tgaaagaaaa aattgacctg ctcgttgaaa acctgacaac
     4981 gatcaaagac gataatggtg aatttttgtt ggactttgat ggactgaaag tagatgacaa
     5041 aagctggaca gtgtggaatt ggccacaagg tgtcggtcta tatggtattt ataaaaatta
     5101 ccagatgaca aaaaatcctc gcgcttatca agtggtcaat gaatggtttg aggatcgtat
     5161 ggaagaaggc gctccgccca aaaacgtcaa tacaatggca ccgctattga ctatggctta
     5221 cttgtatgaa gacacgaaag attcacgcta tttgccttat ttagaacaat gggcagaatg
     5281 ggtcatgaat gacatgcctc ggacaaatga agacgggtta cagcatgcca catatggacc
     5341 ggaaaataag aatcagttgt gggacgatac attgatgatg acagtgcttc ctttggcaaa
     5401 aatcgggaaa ctgttgaatc gcccagaata tttagaagaa gctcgttacc agtttatgat
     5461 ccatatcaaa tacttgatgg ataaacgaac aggattgtgg tatcacggct ggacgtttga
     5521 aggaaatcat aactatgccg aagcattttg ggctcgtgga aactgctggt tgacgattgc
     5581 tattccagag atcattgaaa tcttagaatt atcgaaagaa gatgcattgc gcaaattatt
     5641 gatcgaaaca cttgaagcac aagtgcgtgc attaaaaact tatcagtctg aaagcggttt
     5701 atggcatacg ttgttggatg atccttcttc ttacgtagaa tcttctgcaa ctgcaggatt
     5761 tgcttacggt attttgaaag cggtccataa acgttattta ccacaagaat ataaagaagt
     5821 cgcttatcgt gctatccaag gattgcttga acaaatcgat gaaaaaggag aagttcaaaa
     5881 cgtttcaatc gggacaggaa tgggggacag tttagatttt tatcggaata tcggaatcac
     5941 agcaatgcct tatggacagt cgttaacggt gctttgtttg acagaattgc tcgtctctta
     6001 ttgttaaaag aaaggaaacc catatgaaaa aaacatcact gctgtttgca gcaagttcgc
     6061 ttagcctagg tctgctaggt ctaagcggct gcggaaataa ttctagtgtg gcaactgtcg
     6121 cagatgcaga tgtaaatgag atagttacct tgcgctttgc ttatgcaagc aacagccagc
     6181 cagtaattga tgcaatgaat gaatttgggc gtttagtaaa agaaaaaaca gatggttccg
     6241 tacagatcca gtatttccca gatggacaac tgggtggaga acgtgaactg atcgaattga
     6301 cacagtcagg agcagtagat ttcacaaaag taagtgcctc agcgttggaa agtttctcta
     6361 aagattattc gattttttca gttccttatc tattcaatga tgaagaacat ttctttaagg
     6421 tgatggataa tgaagaaata atggagccaa tctaccaatc gaccaaaaat ttaggattta
     6481 ccggattgac ctattatgat tctggtcagc gcagctttta tatggtagac ggtccgatcc
     6541 atacgccgga agatttggag ggaaagaaga tccgtgtgat gcaaagcgaa accgctatca
     6601 aaatggtaga gcttttaggc ggttcgcccg tacctatggg aagtgatgaa gtgtacacgt
     6661 ctcttcaatc caatttgatc aacggatcag aaaacaatga atttgtcttg tatacagctg
     6721 gacatggtgg tgtggctaaa tactattcct atgatgagca tacacgtgtg ccagatatca
     6781 tcatcatgaa tgatgccatc aaagaacagc taactgatga gcaggaaaaa gccattgaag
     6841 aagcagcgaa agaatcaacg gtttttgaaa ttgaagcttt tgcaaaagca attgaagaag
     6901 aaaaagcttt agcacaagaa gaacatggag tccaattcaa tgatgtagat aatacaccgt
     6961 ttcgagaggc agttgcccca cttcatgata tattcaaaaa cgatcctacc tacaaagacc
     7021 tttatcaaaa gatccaagag caaggagcgt agctgtgatg aaaatgattt taaacaaggt
     7081 attagagatc ctgggagctg ttttgcttgt tgggatggtc gctgttgttt tatggcaagt
     7141 attttccaga acggttttag gaaatccaaa tacggtcacg gaagagcttg ttcgattcgg
     7201 tcttgtctgg tttgccatgt tgtcttccgc gtatgttgtg ggacaaaaag cacatttagc
     7261 cgtaacggtt ttaagtgaaa aattaactgg caaaaaaagt aaaattttag aagttgttgt
     7321 tcaaagttta tttctggtat ttgctgcgat gatcatggtg tatggcggat ggaatgctgt
     7381 cacattgaca atggggcaga tctcgccttc tttaagtatt cctatgggat atgtttatct
     7441 gtcagtacct gtatcggggg tactcatcat tatctatagc ctgatcaatc taatcgatac
     7501 attaagcaac aagccagcaa ttcaagaaaa aatataaaaa tggaggaata aaatggcaat
     7561 agaagccgga ttagtgttat tttttgtatt tgttgtgttg cttgtattag ggatgccgat
     7621 tgctataagt attgcattct catcgatgat gactttattg ttagttatac cgtttgatgt
     7681 ttctgctttt agttcagctc aaaaaatggt gggaagtatc aatagttttt cgctgatcgc
     7741 tattccgttt ttcgttctct cgggcattat catgaataat ggagggatag ctaagaaact
     7801 agtggatttt gcgatgttgt tcgtcgggcg cgtgccgggg gctttggctc atacgaatgt
     7861 gttagggaat gctttatttg gttccatctc tagctcggcc attgccgctt ctaccgcgat
     7921 tggcggagtg ttgatccctc agcaagtgga agaaggatat gaccggaagt ttgcgacagc
     7981 ggtcaatatc gcgtcagctc cgacaggtat ggtcattcct ccaagtactg cttttatcat
     8041 gtattcactt gttgctggtg gtgcttcgat ctctgctttg tttatgggag gttatctcgt
     8101 aggcgctttg tgggcgctag gaatcatgct agtagcattc atcgttgcta aaaagaataa
     8161 ataccctgtt gtcgaaaaag gacagatggc tcatgctgga aaaataataa aagaggcgat
     8221 tcctagcctt ctattgattg tcatcattat cggtggtatc ttgacgggga tatttacagc
     8281 agtagaagct tcagcgatag ctgtcattta ctccctgttg attgctatgt tttactataa
     8341 aacggtaaaa ctaaaagata tacctaatat gttgtttcaa tcagtagcaa tgtcagggac
     8401 gatcatgttc ttattggcta cttcttccat gatgtctttc gccatggcgt ttaccggtat
     8461 tcctcaggca attagttcgt tgattatggg cgtaacggat aataaattta ttattctgtt
     8521 attagtcaat cttgtgttat tactggtggg tatgtttatg gatgtggcgc ctgctatctt
     8581 gatttttaca ccaatatttt taccaatcgt cacaagtgta ggggttgatc ctgtacatta
     8641 cgggttgttt tcaatcatga atctgtgtgt aggctccatc acgccgccag taggtacagg
     8701 actatatgtc ggtgcaagtg taggaggcgt aaaagcagag gcaatgctga aaccgcttct
     8761 tcctttttat ggggttatct tagtcgtctt gtttttgatt acttacttcc cgcaaatcgt
     8821 catgtggcta cccaatatgc tgagttagga gaatagttat gttgaacatt acaattagag
     8881 gacatgatct ttccgaagtc caaacgatag aagatcttgc agaaaaaaca aaagaacaag
     8941 ggattcatac actgcagctc gccttaggtc tttcgtttcc tgaaacacct tctggcgcaa
     9001 atgagatcaa ttctgggatg ggaaattatg tcaaacgagt tttagaaaag caagaagtga
     9061 ccgtaggaat tttaagttgc tatatcaata tgattcatcc agatttaacg atacgacaag
     9121 agttgctgac aaagttcgag cagtatcttc gctatgcttc ttcctttggt gcgtcgatgg
     9181 ttgcttcgga aactggatgt gttttgccgg aaatccaata tacggaagaa aatttcacag
     9241 atgaagcatt tgctgaagct gtgtccgtta tccgtcgctt ggtaaaagct ggagaaaaat
     9301 accaaatgat ggtggggata gaaccaggtt tgaatcatcc ggtgtattct ttagcaaggg
     9361 tagagcagct gatccaagca gtagattcgg actatctagg aatcatttta gatccgacca
     9421 atttgatcac aagtagtgat tatcaagaac aagtccaatt ggtagaagaa gcttttgaac
     9481 gttttggtga aaagatatgt gcggttcatt tgaaagattt tcgtgtcgaa caggaaaaaa
     9541 tcgtgccggt aaatttggga gacggtgtga tcgagtacac aaaaatcaaa gaaatcatca
     9601 tgaagaatcg tccgtacctg tatgtggttc ttgaagaaac aaaagatgat gggattcgtt
     9661 atggaagaag tcttcttgaa taatgtaaag aagacgttgg ttaactaata tttagaatgg
     9721 agggggcggg gctagaagat gccacgtctc ttctttttta taagagtata taaaagcagc
     9781 tctttttgat tacaaaaaac gtggtataat aaaattgtgc ataagtgaac aaaaggaggt
     9841 gcggcacatg ctccaaaaga aaatcagcgg tgaacaagtc aatacgatgg tttctgatca
     9901 gtatgaaatc tatcatgtca aagatgtcgt cagccaaaat aaaacgatct atcatcatca
     9961 tgatttctat gagatccatg ctacattaaa gggagaagcg actttttatt tgaacggacg
    10021 acaatttacg atcaaagcag gaagtgtgct gctcatccat tccaatgatt tgcatcgtat
    10081 cgtccgccaa tcttcagatg tattcgagcg tgtctatatc tttgtcaccc cttcttttct
    10141 agaaagtcgt tccacgccat ggtctaatct atcggcttgt tttcaaccaa tgggagagaa
    10201 gaggagtcgt gtattgcaaa tagaacagga agtattgaag caaaaattat catttatcga
    10261 ccatcctcct gataaaaaaa tttacggtga agacataaaa tatgaacaag ctctggtaga
    10321 atacttgatt tttctcaatc aagttgtaca aaaagaagag agtgcgcaag aacagaatgc
    10381 tgtagttcct aatgagcgtg tggaacaaat gttacaatat atctcaaaaa atttatctca
    10441 tccgctttct ttagaggaaa tggaaaagca gttttttgtc agcaaatacc atatcacacg
    10501 agaatttaaa aagtacactg gatttacgtt tcatcagtat gtaatgaaga aaaagctgat
    10561 ctatgccaag cacttgttgc gagaataccg cagctctagt gctgtatata gtaaaagtgg
    10621 tttttcttct tatccgcatt ttctgaaagc attcaagaga gagttcggca taacgcctaa
    10681 agaatttttg aaacgtgata cacagaaaca gttggttcat tatgaacatt ttgaagatga
    10741 acaatgagaa tgatcactaa aaaataaccg cagtagctgc tgttgtttac atagaagcag
    10801 aaactgcggt tattttattt ttatctatat atttcaaaat attttgaaaa aatgacgtac
    10861 atattatatg aatcagctga atttacgaaa gtctctcggc gatagtcctg tttttgcttt
    10921 gaacaggcgg ctaaagtaag caaaattctc aatccctatt tcttcggaaa tcattcgaac
    10981 cgtaaattct gtataccgaa gaaggtcttt agcgtaagaa agttttttgc tgatcaaata
    11041 atcgattggt ggagaaccga taaatttgga aaaatctttg ctcagctgat atttattcaa
    11101 taagaattgt tgttctaatt gatcaagtgt aatcgtttct ttgaaatgtt cgtctaagta
    11161 ttgcttcagt ttgtaaacgt aggcgggaat atcctcttct tcgaaatcta gctgatactt
    11221 ttgcaaaatc agttcattca gcaactcgtg gatagctaca gaggactgga aatcggtacg
    11281 ggcattcgtg ccttgttgca tgtggatcaa ttctgtgatc aaatggtgga tcttgttttc
    11341 tgatggatcc cctgttgaat ggaaggtgtt atggccgtct tttgtgaact cctgataaaa
    11401 tgattggacg ttctgaccat tcaaatggat ccaatccatt tcccatggtt cttcgctgat
    11461 cgtttgataa cgctgatatt cttggcagtc aataaaaaat aagtctccag cttttagctg
    11521 ttgctgatta tcattatatg taagcgaacc tttgccagac aaagtaaact ttatcaagta
    11581 agaaggtaaa tgtgctcgtt cagtatagta agggattggt gctttgaagt aaccgatttc
    11641 ttggatataa aaaaataaat tcctgcttct ttgtgtaggc gtcaagatca ctctttttga
    11701 gtcttccgac catgagtggt tggctttttc ccagtaatcc atgtaaacac tcccaacttg
    11761 tcaagataat gcaattatat accaaaatag tgtgaagcaa aatataagat tctgtattat
    11821 gatagcattg ttaataaatg ataacgcttt attaataaag tgctaatcaa caataaagta
    11881 aaagaggtgg agaaatgaat ccaacatttg ttgccatcga tatcggtgca tcaagcggac
    11941 gactaatgaa aagtacgagg gatgcaaaag gttctttgat cttggaagaa gtacaccggt
    12001 tcaaaaacgg ctttcggaac aaagacggtc acgatcgctg gaagatcgat tatcttatca
    12061 aagagatttt gattggattt gaaaaattaa agcagacagg gattgatcgc ctttttgcgg
    12121 ggatcgatac atgggcagtc gattactgtc tgattgatga acaaggggat cggataaatg
    12181 atccgattgc ttatcgggac aagcgtacca atggagcagt agaacagttt tctgaaatct
    12241 attctctaga taagttgtat gagcagacag ggattcagat ccagcctttc aataccttgt
    12301 tccaattgtt tgctgaagaa aaagaaaatt tggcaaaagc acataaattg ttactgatac
    12361 ctgattattt agggtatgtc tttactggta acatggtgac ggagaaaact aatgcatcta
    12421 ctatgcagct gctgaatgca gggacaaaag aatgggaaat agaacttctt gaaaaaatcg
    12481 gtgtctcgaa ggaattattt ccaccattga cagagccggg aacgatacta ggagatctgc
    12541 aaaaagaaca attttcaaaa tatgatttgc cagatgtgac ctttatcaca gtagcaagtc
    12601 atgatacggc gtcagctgta ttaggaacgc caggtcaagg agaacgttgg ggttatatca
    12661 gcagtgggac atggtcgctt ttagggattg aaacaaagat cgccaatgtt tctcgcaatg
    12721 ctttttctga aaattatacg aatgaatggg gtgcccataa cacggtgcgt tttttgaaaa
    12781 acatcatggg gatgtggttg atccaggaag ttgcccgaat gcaagagtac gagtacagtt
    12841 atgcggaatt ggcagagctt gctgcaaaag aaaaaccgct gcagcaagtg atggaaatca
    12901 atgaccctcg atttttgaat cccccaaata tgatagaaga gattcagcaa tactgttttg
    12961 aaacagagca gccagtccct gtctcatcgg gagctatcgc tcgttgtgtg tatgataatc
    13021 ttgctctttg ttacgcacaa gagctgatca aagtagaaca cttaactgga acgaaattgg
    13081 aaaagctgca catcgtaggg ggcggatcga ataatcgtct actgaatcaa ttgacagcag
    13141 attatgccgg aatcattgta gaagcaggac ctagtgaagc cacagcaatc gggaatgttg
    13201 ccatgcaaat gctcagtaca ggtcagtttt cgaatataga acaagcaaga aatgtaatca
    13261 aacagtcgtt tccatgtgaa actttttacc cagatgaaaa taagcaaaac acgatggaat
    13321 ggtacgtgaa taaaatcaaa ggagtaatcg tatgaacacg attgaaagaa attacgaaca
    13381 agcaaaagaa aaatatgcaa ctatcggtgt agatacagat gctgtactag aaaagataca
    13441 ggacatcaaa atttctatgc attgctggca aggagatgat gtcaaaggtt tcttgacacc
    13501 ggatggcgaa ttgaccggtg gaatcatggc gacagggaat tttccaggag ccgcacgaac
    13561 acctgaagag cttagacaag atctggagaa ggcttattcg ttgataccgg gcaaacacaa
    13621 attgaacctt catgctatct atttggatac agaagaatct gtcgatctaa atgaaattga
    13681 gccgaaacat tttgaaaaat gggtagagtg ggcaaaaaaa gaagaaatcg gtcttgactt
    13741 caatccgact ttcttttcgc atccaatgat gaaagacggc tttacattgg ctcatccaga
    13801 taaagaagtt cgtgaatact ggatcgaaca cgggaaaaga agccgcaaaa tcgcggagta
    13861 ctttgggaaa gaaactgggc aaacaagtat caataacttt tgggtacctg atgggatgaa
    13921 agataatccg attgatcgtt ttaccccacg ggaacgttta atggaatcac tcgatgaaat
    13981 ttttacagaa gagttagatg aacggtatgt acaagatgca gtagaaagca aactatttgg
    14041 tttaggcgct gaagcttata cagtcggttc ccatgaattt tatatgggtt acgggttgac
    14101 tcgtgacaaa cttgtttgtc tagatgctgg acattttcat ccaacagaag tgatttccaa
    14161 taaattatct tcattagctt tattcagcaa aggaatcatg ttgcatgttt cccgtccagt
    14221 gcgttgggat tcagaccatg tggttttgat ggatgatgaa ttgcaggaaa tcgctaaaga
    14281 attagtccgt aacgaattgt tggaaaaaac aaatatcggt ctggatttct ttgatgcaac
    14341 gatcaaccgt atcgctgctt gggtcatcgg tacgagaaat acacaaaaag cactgctgaa
    14401 agctatgctg gaaccagttg agcgattgaa agaaatggag ctggcttttg actttacttc
    14461 aagaatggct tatacggaag aattgaaaga tttcccgtat gccgatgtat ggaattattt
    14521 ctgttacaaa aatcaagttc cagttggttt ggattggctg gaagaagtcc aggaatatca
    14581 aaaagacgtg ttggaattaa gaaaatagga gtgtggctat attgaaaaaa atagatattt
    14641 tacaagcgcc ttatgtgaaa gaaatgatcg aaacgacgtc gaatctttat cgcttgggat
    14701 gggatgaaag aaatggcggg aatatttctt atttactaaa agaagaagag atcacaccgt
    14761 tcttggatcc tgaaaaagtg atccgccgca tctcgatgat ttttgatgcc agccgtttag
    14821 caggatgcta ttttattgta actggttcag gaagatattt taaaaatgta gcgagcgaac
    14881 ctgccgagaa tcttggaatc gttcgagttg ctgaagatgg caaaacactg gaacttttgt
    14941 gggggctgga aaacgaatgc cttcctacaa gcgagttgcc aagtcatttc atgagtcata
    15001 tcgcccgttt agaagtagac ccagataatc ggatcgttat gcattgccat gctagtcatc
    15061 tattagcgat gagttttacg catgaattag acgaacgttc ctttagtcgt acgctatggc
    15121 aaatgtgtac ggaatgctta gttgtttttc cagaaggaat ttccatcatt ccgtggatgg
    15181 ttccgggaac aaatgagatt ggggaagcaa cagctgaaaa aatgaaagaa actcgattgg
    15241 ttttatggcc acaacatgga atctacgggt caggaaaaga catggatgaa gtctttggtt
    15301 tgatcgagac agcagaaaag gcagcagaag tctatacgta cgtcaaagcg caaggaccaa
    15361 tcttgcaaac aatcacggac gaaaacctgt ggcatttagc agatgcgttt ggtgtcactc
    15421 caaaagcagg ttatttggag gaagttcata cgaaagcagg tgtctgacat ggtgaaaaaa
    15481 gctttttgca tgaaagttta cccagaaaaa caagaagaat acaaaaaaag acatgatgaa
    15541 ctttggccag aaatgcgtac agcacttcgt gaacacgggg tcatcgacta ttcgatctat
    15601 cttgatccga gtacaagttt gttatttggt tacttagtga tcgaagatga aaagttatgg
    15661 gaaaaaatgg caaatacatc tatcaatcaa aaatggtgga agtacatgga agatatcatg
    15721 gagacaaatc cagatgcctc tccagtcagt tgggaattga tgccagtctt tgaactgtag
    15781 caacaagcaa ctgggcaacc ggttgcttgg ggttctttcg tttttattgt gaaaaaaata
    15841 caaattagga ggaatagaaa atgagtaatc gaatgatttt aaatgaaaca tcgtattttg
    15901 gaaaaggagc gattgagtcg atcgtccctg aatttcagca gcgaggattc ggcaaagcag
    15961 ctgtcattac tgacaaagga ttgatcgagc acggtatagc aacaaaagta acagaacttc
    16021 tagataaagc agcaatcgct tatgctttat acgacgggat cgtacctaat ccaacgatcc
    16081 aaaatgtaaa agatggagtg gcttttgtta aagaggcaga ggcagactgt ttgatcgcaa
    16141 tcggtggagg ttcgccaatc gatacggcaa aagccattgg gattattttg acgaatccag
    16201 agttttcaga cgtcattagt ttagaaggtg ttgctgatac gaaaaatcca tgtttaccta
    16261 tattagctat accaacgact tctggaacag cagcagaagt aacgatcaac tacgtcatca
    16321 cagatgaagt aaatcaccga aaatttgttt gtgttgatcc tcatgatatc ccaatcgtcg
    16381 cgttcatcga cagcgatatg atgatgggaa tgccgaaaaa attggctgca tcaacaggta
    16441 tggatgctat gacgcatgct attgaagggt ttatcacaaa aggcgcttgg gaaatgactg
    16501 atatgctgca tttaaaagca atcgaaatca tcggccattc tttggaagtt tctgtagatg
    16561 gcgatcaaaa tgggcgagaa aaaatggcat taggacagta tattgcggga atgggcttct
    16621 caaatgtcgg tttaggactg gtacacggga tggctcaccc gttaagtgca tggtacaaca
    16681 ttcctcatgg cgtagcgtgt gcagcacttt tgccaactgt catgaaatat aacaaagaat
    16741 atactggaga aaagtaccgt gagatcgctc ttgttctagg gattaaagga gcagctgaaa
    16801 tgtctttaga agatgtaaga gaagcggctt gtggtgagat cgatcggttg agcaaagcgg
    16861 ttggaatccc agaaaccatt tctgaattag gtgtaaaaga agcagatatt ccagcaattg
    16921 cagaagatgc tttgcgagat gtatgcacac caggaaatcc aagagaaacg acagtagaag
    16981 aaatcattgc tttatatcaa agtttgatgt aaaaacgaag cggatcttca acattaaatt
    17041 gcctgtaaag agaaatggta gtttatatct ggatatctct tttaaattga tggtatttcc
    17101 gctataattt ttcttataaa gaaataggag aatattatat ggaaaataaa aagccttatg
    17161 gaactgtatt gatcaaagcc tctaaaatac tagactattt agcggaaaac caagatgtct
    17221 ctttgcagac gatcgcaaag ggtgtgggaa tgacctcttc tacagtcttg aaaatactag
    17281 atactttgtt gatgatcggc tacgtaaata aaaattcaga gaaaaactat cgtttaggtg
    17341 caaagcttat tcgctacgcg aataaaaaca ttgaacaaat cgatttggta gagttgactt
    17401 taccgttttt agaacagctg cagcaaaaga tcgatgagac tatccactta ggggtattgg
    17461 acaacaatga gatcttgtac gtgaacaaac tagatccaaa acatcaaacg atccgcatgt
    17521 cttcaaaaat cggaatcacc cgaccattat acaattctgc gatgggcaaa gccgtattag
    17581 cagaattcag tgaagagcag tacactgatt atcttgaaaa gcatccgttg atcccttaca
    17641 cagaatatac gatcaccaat gcattacggt tgaaaaagga aatccaaacg gtaaaagaaa
    17701 cccacatcgc atttgacgat gaagaaatcg aacgtgatat tttttgtata ggagcctcaa
    17761 tcgtgaaaaa cgaacaaatc attggtgcat ttagtgtaag tatgccgaaa tatcgtttaa
    17821 cagatgagac aaaagaacaa ataatcagtg ccctcaagca aacaaaaagc gaaatcgagc
    17881 aaagaattca aaaataatga aaaaagcgtt tgcaattttt cttttctgcc gtataatatg
    17941 ggtatagatt tccaagttat aaaataaaat ttctaaatag gaaataggtg gagaagatga
    18001 aaaaaattga tattttatct cgattgaaaa acgccggagt gattgcggtg gtacgcggaa
    18061 aaagcaaaga agaagctttg aatgcttgcc acgcaatcat caaaggtggt ctaactggta
    18121 ttgagttgac ttttacagtc cctcaagcag atcaagtaat caaagaactt ttgtcattct
    18181 acaaagacca accagaaata gtgattggcg caggcacagt attagacgct gtcacagctc
    18241 gcttggctat cttagctggc gcagagtata ttgttagccc ttcctttgat caagaaacgg
    18301 cagagatgtg caatctgtat caaattcctt acttaccagg atgtatgact attaccgaga
    18361 tcaaaacagc gctgaaaagc ggggtagata tcgtcaaact atttcctgga agcgcttatg
    18421 gaccaagtat catttctgcc ttcaaggcgc cgatgcctca agtcaatatc atgccaactg
    18481 gcggtgtgag tctggacaat atgaaagagt ggttcgatgc tggtgtcgta acagtcggag
    18541 taggtgggaa ccttttagca cccgcagcta caggagattt tgacaaagta acggaagtcg
    18601 cgcaacagta tgcagcaaaa atgaaagaaa tcaagaggta gctgcttatg ggaaaagtag
    18661 tgacactcgg agaaatcatg ttgcgattgt ccacagagca gggaacccgt atcgattcaa
    18721 gtgaacgatt cgctgcccat tatggcggag gggaagcaaa cgtagcaatt tctttagcta
    18781 attacggaca tgaagcgatt tttgctacaa aagtacctga taacgcattg ggaaaagcag
    18841 tcaaaaagca cttgcaatgt tatggagtag atacgaaaca ggtattatct ggtggatcaa
    18901 gactaggtac ttattatatg gaaactggta gtggcgaacg cgccgcctca gtgatctatg
    18961 atcgtgccgg atcaagtttt gctgaaatgg atcatttgga atggtcgcta gaggagttat
    19021 tccaaggaat agatatattt catgtttcag gaatcacccc agctttgtct aaaaaatggc
    19081 aaaaaatgac gaaacaggtg atagaagctg caaaaaaagc tggctgcctg atcagcttcg
    19141 atatcaacta tcgtggaaaa ttatggacac agcaagaagc cagcgaagta atccatcagc
    19201 ttttaccttt agtagatatc tgctcagctg gaaaaatgga tgctctttat ttgttaggta
    19261 tcgagaaagc gccagaagca gaagaacaac ctctaattta ttattatcaa aaaatgcagg
    19321 aaaagttccc gaatattcag gtgttttatt cgaccaagcg taccgttcat tcagcaagtg
    19381 aaaatgaatt gaaggggaca ttgtggatga accatgaata tgtggaatcc caagtccata
    19441 gaatcacccc aatcgtggat cgagtaggtg gcggagatgc ttttgcaggt ggcgtgctcc
    19501 atgggatttt atccaatatg tctccgcaag aaatcattga ttttgctacg gcagcttctg
    19561 ccttgaagca tacgatccat ggggactgca accaatttag tcaagaagaa gtcgcacaat
    19621 ttttagcatg cggctctgga aaaatcattc gatagaagga gtagaagaaa atgcaagaaa
    19681 tggaaacacg ttatacacac agtccagaag atatccgtca ttattcaacg gaacaattga
    19741 gaaaagaatt tttagtagaa aaggtatttg aaccagggaa aatcagtttg acttatacgc
    19801 acaacgatcg aatgatcttt ggtggagtga cacctactga aaaagaatta gaaatcacat
    19861 tagacaaaga actaggtgtt gattacttct tagagcgtcg tgaactaggt gtgatcaata
    19921 tcggtggacc aggattcatc gagatcgatg ggcaaaaaga agaaatgaaa aaacaagacg
    19981 gatactatat cggaaaagaa acacgacatg ttgtattttc ttctcaagat gctgaaaacc
    20041 cagctaaatt ctatattagt tctgttccag ctcatcataa atatccaaat gtaaaaatca
    20101 gtatcgacca agtaaaacca atggagactg gtgaaggcct gacactgaat gaacgtaaaa
    20161 tctaccaata catccatcca aatgtatgcg aaagctgtca attacaaatg ggttatacga
    20221 ttttagaacc aggaagcgct tggaatacga tgccttgtca tacacatgaa cgtcgtatgg
    20281 aagcttatgt ctactttgat tatgccaatg aagatacacg tgtgttccac atgatgggca
    20341 aaccagatga aacaaaacat ttagttgtag acaatgaaca agccattatt tcgccaagct
    20401 ggtcgatcca ttcaggtgta ggtacaagca attactcatt catctgggca atgtgcggag
    20461 aaaatatcac ctatacagac atggatatgg tgcaaatgga tcaattaaaa taagcataag
    20521 ggagagaaaa tgatggaatt tagtatggat atgtttcgtt tagatggaaa agtagcatta
    20581 gtcaccggtg ctgtctatgg tattggattt gagattgcac gctctttagc tacagcagga
    20641 gcaaaaatcg tatttaataa cttgaatcaa gaatcagttg atgaaggtat agcgcattat
    20701 aaagaagcag gcatcgatgc aaaaggttat gtctgcgatg tgaccgatga agaagcggtt
    20761 caagcgatgg ttcaacagat caaagaagat gtaggttcag ttgatattct agtcaacaat
    20821 gcagggatca tcaaacggac accgatgatc gaaatggatg cggcagactt ccgccaagta
    20881 atcgacgtgg atttaaatgc cccattcatc gtttcaaaag cagttattcc ggatatgatc
    20941 gaaaaaggcg gcggtaaaat catcaatatc tgctccatga tgagtgaatt aggacgcgaa
    21001 acggtcagtg cttatgctgc ggcaaaaggc ggattaaaaa tgctgacgaa aaacatcgct
    21061 tctgaatacg gtcaatacaa tatccaatgt aatggaattg gaccaggtta tattgctaca
    21121 ccgcaaactg ctccattacg cgaaacacaa gaaaacggtg aacgtcatcc attcgatcaa
    21181 tttatcgttg gacgtacgcc agcagcacgc tggggcgagc caatcgattt ggctggacca
    21241 tctgtcttct tggcttctag cgcatctgat ttcgttaacg gccatgtctt gtatgtggac
    21301 ggaggcatac ttgcctatat cggaaaacaa ccttaaaaga gctttagtac actgtttagt
    21361 ggagaggttg tgaaatcagc ggattgaacg aataccgaag gacagctgat taaacatcat
    21421 ttattcgaaa aaagaggctg ggacagaagc atttaactcc aagaaataag aaggaattca
    21481 cgaaaattgc ttttcaaatt tttgtgaatt tcagcttatt tccgaaggag ttgcttttac
    21541 ttccgccgtt tgtacgtgtt tagagcgtga gacaaaagtg ttctttactt ttgtcccacg
    21601 ctcttttctg tgcgtcttcc atacttcact aagtcgatcc ctcttgcttc gcaccaatcc
    21661 ttcactggtc cggaaaagat cagagattgt tggtgtaggg ccgcggtatt cgttgcgccg
    21721 accatagtat aaagcagacg aagctcttct tgccattgct tcatcagtat aatagtttct
    21781 tctacgccgt gattcatcag atgcgtcagt acggttcctg aagtacccac ggcatttgcg
    21841 ccgagacaaa gggctttaaa tatgtcatag gcattgcgga tacctccgga ggctaggatt
    21901 tccatagaag tgtctgcttc atttgcttca agcaatgaag agactgtcga ttgcccccag
    21961 tcagctaaat aactcagttc ccgcttggag cgacgggcgt tttcgatctg ggtgaagctt
    22021 gttccgcttc gaccgctgat atcaactgta tgaactccta aagcagctag atcattgagc
    22081 gtttctcttg tcatgccaaa accgacttct tttacgatga gggggacgtc aatggctgtt
    22141 tgagtttctt gaataagtac tttccaattg gtaaaatcac ggtctccctc aggcataacc
    22201 aactcttgag gtgcattcaa atgaatctgt aaggcatctg cgtgaaacaa tcggatagct
    22261 tctttggctc tttcgacaga agtccctgca ccgatgttgg caatgatttt cccgtgagga
    22321 tattcttgtc gcataatcgt ataagtatcg gctaaagaag ggactttcaa ggcagcgctg
    22381 actgaaccag tggcaatcat caaatctgct tctcttgcga cgattgcaag atcttggttg
    22441 attttttttg ttttttcgct tccgccagtc atcgcattga tataaaatgg gctgcttagt
    22501 gtaaacccaa ctgcctgtgt acttagatcg acatcagaaa ctgctatttg cggcaaaggg
    22561 ttatggatga tccgtacgaa gtcaaattcg tttttttgtt tatcatgaaa ggctttagct
    22621 agtgaaacat gttcgtcttt tcgattcatc ggttttcctt tctttgatcg ctatagacat
    22681 gtaacggcag tggagtgatt tctgcttttt cccatgcact cattaaagga agaatgccag
    22741 atttctggtc aacaattacg attccgcaat cgcccccacc tgcaccagaa gattttgcgg
    22801 ctccttcata ctgttcagct aaattacaca atttgttcaa agcaggcgtt tcgatgacga
    22861 ccccagtgat tgcagataaa tcatgcagta attgtcggtt ttttcgaatc atctgttgga
    22921 tcaacgttac attattttct ttaaaccctt tgatcatttc gttgacacat tctgtactat
    22981 tttttaagaa aagctgataa gccaccattt tatcttctct cgaacggtga acttgatcga
    23041 ccaaatcaga agtagaggca gggctacccg tccaaccaat caataaacgt aaatcttcag
    23101 gagcaatcaa tggctcaatg gatagacctg gccaatccag ggcaagtaac tcactgatag
    23161 aatgctgagt ttcttgttct tggagccaag gatggtcgaa ggttgagaaa gcgatccagc
    23221 caccataaca gctagcagcg atgtcgccgc aggaaccatt atcttgaact gctaaattgg
    23281 ctagtgctgc aatcttgaaa atctccaact gagataaatt caacgcgtaa aaaacattca
    23341 aggctttgac cgttgcaacg gtcacggcac cgctagaacc caatccatat ttccggccat
    23401 ttgaactgtc taactcactt gttactttca gatcataaaa ggataaaaga atgttttttt
    23461 cttgtgcata cttttcagtc aagcgaatag cagcaaggat ataatgaaaa ggattttccc
    23521 gaatatctaa aactaattct ccgttgcgtc ttgtccaacg tacaggcatc ccactatatt
    23581 gtgcagattg gatacttccg acttttcgtg cagattctac agtgactgtc acgaattgat
    23641 cgactgcagc gataactgct ggatggcctg tttcaacaac tgcatattct ccggcaatat
    23701 agagtttgcc tggtgcagat acttcaatca taaaaatctc cctttattca ataatcgcaa
    23761 ttcctggacc agcatgtgca gtaattactt gttctttgct aaataatttg gtaaatgttt
    23821 cttgtacctc agataaatgg ctgttttcca ctaaaacttt gacattaggg ccagcatcca
    23881 tcgtaaagta gcatggaatg ccttgctttc tcaattgtcg caccgcatcc atcgctttta
    23941 agctgtcagg agaccagtaa gtgaatggag gctgggcagc taaagtcgtt ccatgcattt
    24001 ttagtccgtt tctttccatc gtttctccga gaagttggaa atcttttgtt ttgattgctt
    24061 gtttcaattg atatagatcc ccttcaacgg aatctaacca gccttgataa aaactggatg
    24121 tttcgactgt ccgacgcatc ccatttctgc tggacacttc ttttttctgg tcgttgatca
    24181 aaacgaaaac cattgctaaa tcgtcttcga aagaatcgga agggactggc ttagcgtaag
    24241 aacttaagtc gtcatggcct ttttcccatt cgacgaaacc accgaaaata cttcggcaag
    24301 ctgaaccaga cccgcgtcga gcaaatcttg aaagagagag atcatctaat ccaagcttaa
    24361 gagcagtatt gcaagcgcct gctaaagcag ctagcccgct ggcagaggag gctaatccag
    24421 ctgcggtagg aacgaaattc tgactgatta ctgaagcttt tagtgagagg ccggcttctt
    24481 tacgaaaaag gtcaagaaac tgactgactt tttttgttgc tttttcgtct tgcaaggtgc
    24541 catctagata aaattcatct accatatagc tatcagaaaa gatgacttct gtctctgtat
    24601 aaaatgcatc caatgttaac gaaaggctgt tgttcattgg aaggatgagt tcttcatttt
    24661 tcttacccca atatttgatt agagcaatgt tggtatatgc gcgtgctttg cctttaaaca
    24721 taggtatgta ctcctaatcc ttgtatccaa gtttcagcag cacccgcatc ttcaagtgct
    24781 tgactgattt cttgggcttt tgtttttgtt tgtgctaatg caatcataca gccaccgcgt
    24841 ccaccgccag ttaatttggc acccaatgcc ccggtatctt ttgctgtttg gatcaataga
    24901 ttaagaaaat cattgctgat tgtcagcttt tccagaagtg attgtgattc atccattgtc
    24961 tgtgccaacg tttctggtga attttcaatg attgcttgtt ttgcttgctt cgtcaagtat
    25021 cctaattttt ggatcatttg tccagtttca tgaggctggg tttcaaagag gtgagcgaca
    25081 tctttgacgg cttctcttgt ttgtcctttg attcctgtat cagcgacaat caaaaaagca
    25141 tcgatgttca aagaaaagta gtcgaaagga tgcccttttg taaaataaat cggctgcaag
    25201 ctgctagtag cggctgcatc gattccacta ggattaccgt gggcgatttt ttccgaaagc
    25261 tggacatttt ctaatagtat ttcacgagac aaaggaaatg ctaagtaatc ataaaaagca
    25321 cgagtgactg ctgtggcgac tgcagcgctt gatcccattc cacgttcagc aggaatcgtg
    25381 ctttcaatgg tcagttgcaa gtttttttgg atgtcatgct gtttttttaa gtgaatgaat
    25441 aattttttga tattttttaa tgcatgagga gcttcggcta aatttcctga atagtaggaa
    25501 gaaaccagtt gatcgtccat tgcatccagc tcttcaagga atgcggtgac ttttgttgca
    25561 tagaaaggaa aggcaatcgc tggttctcca taaacaaccg cgtgctcgcc catcaatatg
    25621 atctttccgc ttgattctcc ttggccatag tttgccataa tctaactcct tctcacgtaa
    25681 aagtgatttt taagcaaaaa ataaagcgcc caaaacgagt tgcgctgctt cacgaatttt
    25741 tttgtccact aagggtctca aaaaacattc ctcctttatt ttactaaaac catctcagaa
    25801 gtaaaactaa gaatacgttt tctaaagaaa aaacactttt ttcttaagaa ttttttgact
    25861 ttttttcttc tttgactaga aaaaaataca attgacacta ctagatattg ggggtatatt
    25921 taaaaaggtt ggagttaaac acaatattta gtgatgaagt gagctggagg taaatgagcg
    25981 tgatcgtttt agcaggtaca attggtgccg gaaaatcaag tttaacagaa atgatggctg
    26041 aacactttga tagtcaggca ttttatgaat cgattgatga taatgaagtc ttgcccttat
    26101 tttatgcaaa ccctgaacag tatgcttttt tgctgcaaat ttattttttg aataaacgtt
    26161 ttgcaagcat caaacaagca atgaaagatg acaataatgt attggaccgt tcgatttatg
    26221 aagattcact gcttttccat ctaaatgcag atctaggaag agcaacagaa acagaagttc
    26281 gtgtgtatga tgaactgctg gaaaacatga tggaagaact tccctatgct gcccataaaa
    26341 aacatccgga tttattagtt catattcgtg tatcttttga tacgatgttg gagcgtatcg
    26401 aaaaacgtgg tcgttcgtat gaacaattgt cctttgatcc aagtctatac gattattaca
    26461 aagaattgaa cagacgttac gatcaatggt atgaagaata caaagaaagt ccaaaaatcc
    26521 aaatcgatgg agaccgctat aattttgtgg aagatcctca agcaaaagaa gaagtcttga
    26581 aaatgatcga agaaaaatta gcagagattc gccaaaccaa agtagccatt tgatttacag
    26641 ttgctcaaat aaagggtaaa cctttatttg agcgactttt ttctttatac tggaaacaaa
    26701 tgtcaggagg atagagtatg cgggaaaaac actattttaa tcaagaccgt aatttttgga
    26761 tcaatgtaca gcaaaacgat gtgctagctg ttaaaaactt aaaagaagaa tatggcatta
    26821 gtgacgagat gctgacttat tctctagata aaaatgaacg ggcgcgcgta gagtacgatt
    26881 cttttgatga agcgttactg cttgtatcaa atgttccgca ccagcaaaaa gtcgataatc
    26941 attatgaaac tagtcctatc gcttttattt taaaagaaga cggtttgttt acatttacca
    27001 cgccgaatac cgagtacgtg attcgactaa ttcgatcgct tttggaacga atgccagaca
    27061 tgagtgtata cagtttattg tttcgtacat tgtttttgat ttctgattcc ttttttcctt
    27121 taatcgagga agtgaatagt gaacgtcagc ggcttaatct gaaattaaga gaaaaaacaa
    27181 cgaacaagaa tctgctgcaa ctttcagatt tagagatcgg tttggtttac ttagttacag
    27241 gaacaaaaca aaatgtagta cttttagaac aaatcaaggc attggctatt tatcgcaagt
    27301 tgtcagaaaa ggaaaaagaa gagttggacg atgcgctgat cgaagcacga caagcagttg
    27361 aaatgacgaa cttagcttcg cagattttag accagctctc tggcacttat aataatttgc
    27421 tgaataacaa cttgaatgac acgatgaaat ttttgacggt ctggtcgctg atcttgaccg
    27481 ttccaactat tgtgacagga ttcttcggaa tgaatctcca gttacccttt acccattccg
    27541 ttttcggatg gggaatcgcc ttgatcatca gtttggtctt atctatttgg atgcttattg
    27601 cactgtggcg gcggattcgt tgatctagtc tttgatctgc aaaccaaggg cttgggcgat
    27661 cacaagtgct tgctcttggt tgacgattag tcccgccaaa gaatcttgag ataaagcgat
    27721 tgctgtgaag aaattagtcg taaagtctaa tcccttcaga gaagttcgaa accagttcga
    27781 accggtcaac tgattgtcag acaaaaaaag gtttttccaa gtgacctcat aaaattcgct
    27841 gtcttctaat tgacaatgat cgaaggagac agctttcaag tttgtactac taaaggaagc
    27901 catcgaagca atacaatcag tgaaagtaca gtctcgaaga taactttcgg caaaattcgt
    27961 acctgttaat ttacattgat gaaacacgac ttggtggaaa ctgccaccaa tccactccag
    28021 attggaaaaa tcacattttt caaaaatgac attactgcat tcaaaatgac gtaaaactgt
    28081 tttttgcatc gtaagttttt ggatatgact ctctcttaat accatatttt tggcatcgag
    28141 atagctttgg tcacccccgt tgatcagaag accagagaag atctcctcat cttctaaata
    28201 aaactctccc tttgtaagaa gaggaagaga aggtggaata ggttcgattt ttttcatgtg
    28261 ggttcacctc gtttttcttt agtatagcaa agaagcggga atcactgcta gaaagtctgc
    28321 taatctaatc attttcagaa aaggaagaca aactgtatga aaaacattga caaaaagatt
    28381 agtttttgct atactatgat ggttgagaaa taaaagcaga agcacccgct tctcgcctta
    28441 gttgataatg tcactgggct agatagtttt cactggttct attaggtgaa gtacgcgcgg
    28501 gttctgtaag agaactcgtt tttttattgc cgtttattcg gtaagctttt ctttctctca
    28561 taatatttgg aggtgaatga ccatagcaaa ggatatgatg gttaacgacg gcattcgtgc
    28621 acgagagtta cgattgatcg gttcagatgg tgagcaatta ggagttaaga caaaagcaga
    28681 agcattgaat attgcagaac aagcaaactt ggatcttgtg ttagttgccc ctggtgcgaa
    28741 accaccagtt gcgcgaatca tggactacgg taaataccgt ttcgaacaac aaaagaaaga
    28801 ccgcgaagcg cgtaaaaaac aaaaagtgat caatgtaaaa gaagttcgct taagtcctac
    28861 gatcgacttg aatgacttca atacaaaact tcgtaatgca cgtaagttct tggaaaaggg
    28921 cgataaagtg aaagcttcta tccgtttcaa aggccgtgcc attacccata aagaaattgg
    28981 tcaaaaagtc ttgaatcgct tagctgaaga aactgcggat attgcaacag tggaacaaaa
    29041 agcgaaaatg gacggacgca gcatgttctt gacgctggca ccgaaaaacg acagtaagta
    29101 atttgaatga ctaactggct gttggacagc cgatagtcgg ataacgaaag attttgagga
    29161 ggaaatatag tcatgccaaa acaaaaaaca caccgcggat cagcaaaacg tttcaaacgt
    29221 actggtaaag gcggattgaa acgcttccgc gcgtttacaa gtcaccgttt ccacggcaaa
    29281 acaaaaaaac aacgccgtca attgcgtaaa gcaagcatgg tttctagtgg cgacttcaaa
    29341 cgtattcgcc aacaactagc aaaaatgaaa taagaagtac aaataacaga atctgaagat
    29401 ttatttttat taggaggaat tatacatggc acgtgttaaa ggtggaacag taactcgtaa
    29461 acgtcgtaaa agagtgctaa aattagcaaa aggttactac ggttcaaaac acactttatt
    29521 taaaacagca aaagaacaag taatgaattc atacaactac gcatatcgcg atcgtcgtca
    29581 aaagaaacgc gacttccgta aattgtggat tgctcgtatc aacgcagcag ctcgtatgaa
    29641 tggcttgagc tactcaaaat taatgcacgg tttgaaagtt gctgaaatcg acatcaaccg
    29701 taaaatgtta gctgacttgg ctgttaacga tgcagcagca tttactgcat tggctgacca
    29761 agcaaaagaa gctttggcta aataagctaa acaattataa agaggaaaga agataacgaa
    29821 aagttatgtt ctttcctctt tttttattta caatcctcca tcaaatgaaa caggacaata
    29881 acgtataagt ctaaaatagc ataattaagg ttttttaatt gaaaactgaa catttatggt
    29941 caccctttaa tgaaagcgct aactacataa gttagaatga gtttgactga tatattagtt
    30001 tgcttatcag aaaaacaaaa tggacggagg aataacatga gtgatattat tattggtatt
    30061 ttgttagtta tctcattctt tttcatggtc tggtactgtg taaaaggcta caacttgatg
    30121 gtcggctttg ccatcatggc tactgtatgg atgggattag cgctagtcgg aaacacgttt
    30181 tcaccaaacc cggcgatgga agggcaagga gtaattgatg tgttgacgca tatctatacg
    30241 acggggccag ctgagtacgc caaatcgatc ttggtaaatg tcttctttgg tgcctttttc
    30301 gggcgtgttc tagtagatag cggaatcgca gctaccctga ttcgaaaggt agttgaactt
    30361 ggaggggaca agccaagaat cacgatgagc ttactatgta ttgtaaccgc tgttatattc
    30421 atgtcgatga caggaatcgg accagtgatt tctattgcag ttattgtgtt gccaatcttg
    30481 atgtcattag gtatttcagt accggttgca ctgttctcat ttatgggctc gattatggct
    30541 ggaatctttg ctaatatcgt caatttcaaa caatatcaaa cgatttatgc tggtttcaat
    30601 ccagcggctg aaagctatac ttataatgac tatttccaaa ttggtatgat tgggatgatt
    30661 gtaagcttag ttgtggtact aacggtcgct aatatatcaa tgaacaaaaa gaaacgctat
    30721 gcaatggcag caaacgtacc agctgaaggt ggcgacgcac caatgatctc atggttagcc
    30781 gtattattac cagttttagg ggtcgttctt ttagatcttc caatcatctt aggttttatt
    30841 ctagcaggta tctgggcatt gctgtttact ggaaaattgc gcggaggtta taaagaaatc
    30901 tgtcgtcagt ttgcgaaatt atttacagat ggcgcagtag atgttgcacc aatggttggt
    30961 ttcttgatga ccttagcgat gttcaataat tcagctgcgt atgcttctcc ttatttttca
    31021 gctatttttg gagattggat accgcaatca ccattagtct tggcaatcgt atttgctata
    31081 ttgacaccac taggattttt ccgcggtcca atgaatctag tcggttcagg ctcagctatt
    31141 ttagctgtcg tattagctgt taatccaacg atgtcgccag cctttttgtt cccgttattt
    31201 gcaatcacaa cgattgctcc tcagcattta gatattacac aatcttgggt tgcttgggga
    31261 ttaggttata caaaagtaac ttctcgagaa tatatgaaga aatccatccc aactggttgg
    31321 atcatcggag cgatcttatg cctgatcacg ttcttattgt acgggaacgc ctagtaaaca
    31381 aaacgtcgat aaaaacgatt agatgaatgg aggaaaagaa aatgaaacgt tttgtgcgaa
    31441 tgggaattga tgttggcggt acacatacga aagcagtcgc aatcgataat gcgacgcacg
    31501 aaatcatcgg aaaatcttca gtgaaaacaa cccacgatga tgtccgtgga gtagccgcag
    31561 gtgtcgttca gtcttttcaa aattgtttgc gggaaaataa tatcagtcca gaagatgttg
    31621 tgtttgttgc acattctacc acacaagcga ctaatgcact gattgaagga gacgtagcaa
    31681 aagtcggcgt aatcgggatg gcaaaaggtg gattagaagg ttttttagca aaacgacaaa
    31741 ctagattgaa cgatatcgat ttagggaata agaaaaaaat agagattgtc aatgcattct
    31801 tacctgtcaa acacttaaat gtagaccgtg tttcagaaac gatttcttct ttagaaagag
    31861 aaagagcgga ggtcttggtt tcttctatgg catttggagt agataatggg gaaccagaac
    31921 gagttgttta tgaagcagca tcggtaaaat cgatccctac aacgatggct tctgacatca
    31981 caaaattata tggattgaca agaagaactc ggacagcagc aatcaatgca tctattttac
    32041 caaaaatgct agatacggca acctctacag aagattccgt acgagaagca ggggtcaatg
    32101 tttctttgat gattatgcgc ggagacggcg gagtaatgga aatcaatgaa atgaaaaaac
    32161 gacctgtttt aaccatgctt tccggtccag cagcatcagt catgggctct ttgatgtact
    32221 tgagagcgtc taatggtgtt tattttgaag taggcggaac aacaaccaat atcggggtca
    32281 ttaaaaatgg acgtccagca atcgattatt caattgtagg tggccaccca acatatatct
    32341 cttcattaga tgttcgggtt ctaggtgtgg caggcggttc gatggtacgg gctaatcagt
    32401 caggaatcat cgatgtcggt ccacgttctg cacatattgc cggtctagat tatgcagtat
    32461 ttacggagac agaaaaaatc aaaggtccta aggttgaatt tttctctcct aaagaaggag
    32521 accctgctga ttacgtcaag gtagtgatgg aagacggaga agaagtgact attacaaata
    32581 catgtgcagc caatgtcctt ggattagtgc aagaagaaca tttttcttat ggaaatgtcc
    32641 catctgcacg aaaagccatc caagcattag ctgattattg tcatacgacg gttgaagaca
    32701 tcgcagaaca gatcatggaa aaatcctatg ctaagattga accggtgatt ttagaattgg
    32761 cagacaagta tcacttggag aaagatcaga tttctcttgt aggtgtaggg ggcggcgctg
    32821 cctcattgat tacttacttt agtaataaaa tgggtgtgaa atattcgatt cctgaaaacg
    32881 ccgaagtgat ttcttctatt ggtgtagcac ttgcaatggt ccgagatgtt gtagaacgta
    32941 tcatcccttc gccaagtaaa gaagatatac gatcgttgaa aaatgaagcg atgaataaag
    33001 cgattgaatc aggcgctaca ccagaatcga tcgaagtcca cgtagaaatc gatccacaga
    33061 cttcaaaagt aacggctatc gctactggtt ctacggaagt gaaagcaacc gatctaacca
    33121 aggagatcac aacagaagaa gcactagagc ttgctgcaga ggatatgcga ttaaataaaa
    33181 atgaagtttg cttattggaa aatacacctt tcttttatgt atgcggcgaa cagaatcgtt
    33241 caaaaaatgc tggaagtctt cggatcatcg atcaaaaagg atttatcaag gtccaacgtg
    33301 gacatgcttc atgtatgaaa acaactgcag ccaattatat gacagctgtc gaacaacttt
    33361 gggaagatat ggcagtttat caaactgaat tgattgcccg accagaattt tatctctgct
    33421 taggagcaag agtctctgat tttacagcga cggatctgga acaactacag cttttgatgg
    33481 atctggaagt atctactatg gaaccggagg aagaagtgat cgtcgttgcc ggaaatatca
    33541 aacaaacata agttagaaga gttactaaac gaattacaac agatccccga agaaatttgg
    33601 ggattctacc agtttcggcg agatttattt tggaaaaaga ttcctttgtc caagcagaaa
    33661 attcttatac aacaatcaat cgattgtggt atcgaaacgg catgtagcat caaaaaaaag
    33721 tacccttttg ccgatgtagg agaaatttgt gaacaaatgg ctgttccaat cgtttcctgt
    33781 gaatcagagc aaataaacga acgaatcact tttgcaactt atgcagaaga tgaagggatt
    33841 cgattgatga cggagccgtt agaaaaatta aaatgttcag gactagcttc gatctctaaa
    33901 gaaacagcgc aagctttgat tattggacat gaactatttc accacatcga agcttctgtt
    33961 aagggaattt atacgcaaag cgaaaaaatt gtgctgtggc ggttgccttt ttatacacat
    34021 caatcaaaca ttcgtgcatt gagcgagata gcagcgatga gtttttcaaa agagatgaat
    34081 caaagcgatt tttcgcctta tgtattagag gcagtcttac tttggccata taatgaaatt
    34141 cgtagccaag ggatcttaga agaaataaaa aaaatagaaa aaagatgtac ggagtatgat
    34201 ttagattaca aataaagaga ctgtgacaaa agtcgtgtca cagtcctttt tttccgaata
    34261 aacgatgttc tcctgtcaac tcctcggtca caagtcaaaa tattcaacaa acatgagaag
    34321 ctgttttttg aaattgttcc ttgtgactcg gagatgaacg gcaggctcac gacctcttgg
    34381 aaaacggtgt tcaaaagctt gcatctgcgg taataagtcc agccaagtta aaaacataag
    34441 aagctatttt tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct
    34501 caataaacgg tgtgcaatca gctgaccctc ggtattagct caaaaaaaac ggcaaaatat
    34561 gaggaactat tttgccgttt ctttctctaa tactcaggtc aaaacgctga ttccaaaacc
    34621 tcttatttga tgggtctgtc ctgaatatct tcaaaataat cggggtaatt atgaatcacg
    34681 tattcttgct cctcgataat catatgtaaa tgcatcgtgc aaagaaatcc gacttcatca
    34741 aagttatgat caatcattga ttgaagcatt gtctgatgtt catctaatac tcgaccccag
    34801 tctaattctg aaatcgtcaa acgtaaccat ctgaaacggt tcaagtgcgt actataactt
    34861 tctagccaat cccaaatttc tcgttttcca gcaatttcat aacaagttcg gtgaaaatca
    34921 gtatccaaat caaaaaaagc ttttttattt tgagcgatta ctgcctgatc ggtttttcca
    34981 acttttcccg cgtataacgg gctaatgaag cagatcggat atcgattttt gaaacataag
    35041 tgccggactg tggaatggtt tttacaagct cttgattgcg cagttggatc agtgcttctc
    35101 gaatcggtgt acgcccgata gctagttgtt cttctaacac tttatcggag attttacttc
    35161 caggtgctaa ctcggaataa atgatttgtt tacgtataga ttcataagct tgctgttgca
    35221 aattattgat aaccatttaa ccttcctttc tatgcagata taatctatta taacataaat
    35281 cgcttacaaa tcgtgtgggc ataaaaacac agtctgcaaa aaaagccctg ataggcatgc
    35341 ctattagagc ctcgaaaaga aaaatattga atcaatctgg tcgtacctct tgtatcggtt
    35401 tgacacgacc gccgattctt ttagcaaaag cttcggattc ttttttgtct ttgaaaatga
    35461 gcagattgtc taagtttttt tcccgagtgc gacagccagt tttatcgatg taaccgtgca
    35521 ttactttaac gacatacatg gggatcacct gcttttttct tttcattata cgaactactc
    35581 gacacaatac aagaaaaatg cttagacggt ctttattaag aatttacatc atccaaagaa
    35641 gcgtacgctt ggaataactg atctaactcc ggattgactt tgctcagctt cactaatcgt
    35701 tgcgaatcag aaagtaaaaa acagtgttta ctactgccag tagtttttaa ttttttgtct
    35761 tcagttccca caatttcgta gctaaaatcc aaccgtgtcc ccgtatactt ttggatagtt
    35821 ggatggatgc tcactttttc tccgtaatgg atcatttctt tatagctgca atttacttcc
    35881 agaacgggga tgatgatccc agattcttcg atttttttat agggaaaccc tagatgtacc
    35941 aataaggcta cccgagcctc ttcaaaccag cggatataat tgctgtgatg aataatcccc
    36001 atttgatctg tttcataata aaaaggttct cgcacataac ctgtaaattt ctccatgact
    36061 catgcctcgt tttccattga ttttttacaa aaataattca tccatttcgg aagtgcttcg
    36121 ctgatttgtg tcggcaaaac aatatattgt tcttttgcca gctggtctcc aatgaaacta
    36181 tgaagataaa tagctgctgc aatcgtttgg tcattttgag gaaactgggc taaaaatcct
    36241 gtgatcatcc cagctaaagt gtcacccatg ccgcccgttg ccatagcagc agaacctaaa
    36301 ggattggtgt agaagtgctg gtgaccataa atttttgtct catgactttt caaaacgagc
    36361 acagcaccga tttcctgttg cttctttttg ttttctttat cccgttgttc ttgtatcggt
    36421 agagaactca accgttgcca ctccatttga tgaggtgtaa gtacagtttg ttcgggatag
    36481 ggtagcaaaa gatgattagc agcaagtaaa cttaaagcag agccatcaat caccagccat
    36541 tgttcttttg attggttttc tagtacttgt ttgaaacgtt ccaaactctt agaagaagta
    36601 cccaatccgg gaccaatcaa gagtacatct gcttgcttta ttacggaaag aaactggtca
    36661 gtatccgtcc aaactacaat cattgcttct ggcagatgac tgtgaagagc actccgattt
    36721 ttttcatcag ttactacagt cgtgagaccc gctccgctgt gtacggcagc taaagcactc
    36781 ataatgattg ctccgccata ttgttcattg ccgccaatca aaacgatacg tccaaatgtt
    36841 cctttatgtg aaatttttgg acgaggtgtg atgactcttt tcactagttg ttcgtttatc
    36901 agcatctaaa aacctccttt tactcattat agcgtatatt ttttttagag aaaaacagat
    36961 aagaaaagga attgtcagat tttttgaact atttttttct gtaatttgtg gtatcatgaa
    37021 cacgaagact taaataagtg gaggattaac tttatgacaa ttgattggca aaaagaagta
    37081 gaagcacgta aagaagactt gcttgaagac ttgaaaaatc ttttacgtgt caacagcgag
    37141 cgcgatgact caaaagtaac accagatgca ccatttggac ctggacctcg cgacgcattg
    37201 aaacatatgt tagcttatgg cgaacgtgat ggatttaaag taaaaaatgt cgataactat
    37261 gcagggcata ttgatcttgg cgaaggagac gaaacgctag ggatatttgg acacatggat
    37321 gtcgttcctg caggagatgg ctgggacaca gatccttatg aaccagtaat caaggatgga
    37381 aagatctttg cacgcggatc aagcgatgac aaaggtccaa gtatggcagc ttactatgcg
    37441 atgaagatca ttaaagaact tgacttgaaa ctatcaaaaa aagttcgctt cgtagtcggc
    37501 agcgatgaag aaagcggctg gggcgatatg gcttattatt tcgaacatga agaagaacca
    37561 gattttggtt tctcaccaga tgctgaattc ccaatcatca atggtgaaaa aggaaatgtt
    37621 tctttagctt tacgcttcaa aggcgacaat gcaggagatt atgtcttgaa atcttttgtt
    37681 tccggacttc gcgaaaatat ggtgccagga acagcaactg cagcacttca agtaccaagt
    37741 gcagatgcag ctatcgcgat ggaagaagca ttttaccaat tcatcgaagc aaatccagta
    37801 agcggaacga ttgaagcgga caatacgtat gtaaaaatcg aattagttgg taaaggcgca
    37861 catggtgcaa gcccacaatc tggtatcaat gcaggttctt tcttggcatt gttcttagat
    37921 aactatgaat tcctaggatc tgctaaacaa tttatccatg tagcagctgc ttatgtccat
    37981 gaagattttt atggagaaaa actaggagtc gcttatgaag atgaaaaaat gggcaaattg
    38041 acaatgaatg ctggactatt tgcttttgaa gaaaatggta cagaggaagc gaacttcatc
    38101 aatatgaatt tccgttttcc aaaaggtgta acagtagacg gattgcaaag tgacatcgaa
    38161 caaacagtgg ggcaagaagg cgcaacagtt actcgaggtg ctcgcgtaat ggaaccacat
    38221 tacgtaccaa tggatgatcc attggtggct acattattgc aagtctatga agaccacact
    38281 ggagaaaaag gctacgaaca aatcatcggt ggcggaactt acggacgttt gttgaaacgt
    38341 ggcgttgctt atggagcgat gttcccagga tatactgata caatgcatca agcaaacgaa
    38401 tttatgagtc ttgatgactt gttcagagca acagcaatct atgcagatgc catctatcgt
    38461 ttggcgaaat aattaattaa aaagaggatc aagaattgca aattattttt gcagtcttga
    38521 tccttttttt actttctact gtggtattca tgataaacat gatatagatt caattcatat
    38581 tctttcttag cgttcgtgac gactgtatcc aaaatcaacc ctgttactaa tgaaagaagt
    38641 gctaaagtca tcaatccagt acttaaaatc gcagaaggga tgcgtgtaat aaagcttgtc
    38701 agcatatatt cgcgaatcac aggaatcccc gtgaccaatc caaataaaaa gaagaagatg
    38761 gtccaaatcc caaagaaaag caaaggctta taatctttaa acattttaat aatcatcatg
    38821 atcactttga atccgtcaga gaatgtattc aattttgatt cgctgccttc aggacgatca
    38881 cgataatcga ttgggatttc aacgaacttg aattttttat ctaaagcatg gatcgtcaat
    38941 tccgtttcga tttgaaaacc agaactcata ataggaaaac ttttgacaaa gatacgattg
    39001 aatcctcgat agccggtcat gacatcaaga atttttgttt tatacattct agtaattgta
    39061 tttctaacaa ggttatttcc aaaatcgtgg aaaggtctct tattctcatc aaagtaggtt
    39121 ccatttgata ggcgatcacc aatgaccata tctgcttcac cagaacgtaa tttctcgagc
    39181 aaaccatgta cagcttctgc aggataagta tcatcgccat ctaccattaa ataatagtcg
    39241 gcatcgatat caaagaacat ttggcggatc acatttcctt ttccttgacg aggttctttt
    39301 tttacgattg ctccaccttg aacggccaat tcgtatgttc gatcggtcga attattatca
    39361 tagacataaa tatctgcttc tggtaattct cgtttaaagt ctgcaatgac tgttgaaatt
    39421 gttgcttcct cattgtaaca aggaatcaga acagcaattt tttcttgttg ttccattttt
    39481 cactctcctt aactatagaa aacaaaagct aaattaaaaa tacctcataa tcaaaggaaa
    39541 tgctagtttt tcccgctaaa tatcatttat ttaaaaagaa aatactggaa tatatgtttg
    39601 gaaagctcta tctaaaaaac cacccactac aaaagaagga catgatacct ctcttttgaa
    39661 tagtgggtgc gtattcgttc tctcactttt ttgacgtatt aatctgttgc accttttttt
    39721 cttgaaattt ctaatacggt tcctgtatga gcatctgcta aaaattcata ataaacagtt
    39781 tcgccatctt ctattcgaga aagacctccc cgataagcac tcgaccgaac ggcgaatttc
    39841 ctaataggtt ccttttcaaa agagatccaa gaaccttcga ttgcaccttc ttttagaaaa
    39901 gatgacttga tattttcaag tacttggtct gctgacaata cttttttgcg atgataccaa
    39961 atcgttgaag ctaccccgct caataatcct agaccgattc caactgctaa cccgccttta
    40021 aaatagctta gttcgctttc ttcatacatg tggacatacc tccttcttct cacttgttac
    40081 tccttgtgct tattttacca cactctcata ttttctttga aataaataac cgctaccaga
    40141 aaaaataagc tataataaat acgatcggtc tgcagaaaaa atcatatttt atccgcagat
    40201 caatataagt ctgagaggag tttagtctga aatttagacg aatagcatat ggaagaaaaa
    40261 acatttcaac gaatcaaaga gttaacagaa ttacaaggaa caagcggttt tgaacaagat
    40321 gttcgcgctt atatggaaag tcatatggaa ccgctggtag atgagttaca gttagatggt
    40381 ttgggcggca tttttggtct gcgccatcat gaagaagcgg atgcaccccg tgtaatggtc
    40441 gcagcacata tggatgaagt cggattcatg ctgacacaaa tccaagaaaa cgggcttttt
    40501 aaagtcgtac ctctaggcgg ctggaatcct tacgttgttt ctgctcagcg ttttacactt
    40561 aaaacctcta ctggtaagaa ttatccatgt atttcttctt ccgttccccc acatttattg
    40621 cgaggaacaa gcggacaaaa atcagtagaa gtaaccgata ttttgttcga tgctgggttt
    40681 gaatcaagag aagaggcaat gagttacggt gtccttccag gagacacaat cgttccttac
    40741 gctgaaacga tcaaaacagc caacggaaag aatattatca gtaaatcatg ggacaaccgc
    40801 tatggctgta caatggtatt agaagcttta gaagcgttgc aaaatgaaac attaggtcat
    40861 acattgattg caggcgcgaa tgtccaggaa gaagtaggct tgcgtggttc taaagcttct
    40921 gtcaataaat tcaagccaga tctgttcttt gcagtagact gctctgcagc agatgataca
    40981 gtgacgaaaa atggcacatt cggacattta ggagaaggta cattgatgcg tatccaagat
    41041 ccaggtttga tcatgcttcc tcgtttgcgc gagtacttgc tggatatcgc tgaaacaaac
    41101 aatatccctt atcaatactt tgtttcaaaa ggcggtacag atgcaggtgc tgctcataca
    41161 caaaacgaag gaatcccaag tacagtgatt ggcgtagtgg gacgttatat ccatacgcat
    41221 caaacgatgt tcagtattcg cgattttgaa gctgcacgag aaatgttgat tcaaacactg
    41281 aaaggtttgg ataaatcaac agtgaatacg atcgtatacg gaaaataatg cgatagtgaa
    41341 actataaaat ctggcaaaag attgcttttt gccagatttt ttttataaaa agaggatcaa
    41401 tgtttgttag ttcgaaagaa aggtgtataa tttaattgaa aaatacataa acagaaagta
    41461 gaggacaaag aatgattatc ccaaatagtt tagaagaatt agcaggctac gtagaaactg
    41521 gaaagagtgt atttttcttt actgccggct ggtgcggaga ctgccgtttt atcaaaccgc
    41581 aaatgcctga aattgaaaat gacttttctg attggcaatt tattgaagta gaccgtgaca
    41641 agtacataga tgtagccgct gaatggaaca tttttggtat cccaagtttt gtcgtgatcc
    41701 aagacggaaa agaattaggt cgtctagtga ataaagatcg taaaacaaaa caggaaatcg
    41761 aatcgttcct agaaagtgta acaaaaggct gacatctgtt aggaggggtc aagatgaatc
    41821 aagaatataa gaatatttta gtaggtatcg acggtagtga acaagcactt gctgctttca
    41881 aaaaagcggt agaagtggct cgccgtaata atgggaaagt atatgtagca aacgtaatcg
    41941 atcagcaatt ttataacttt atgggctatg cacctattga tcaaaatcta gtcgatcagc
    42001 aaactgaaac agccaaggaa atgatcgaag aatgtaaaga atatgggaaa tctgttgatt
    42061 acacaaatat agaaggaatt attgcatatg gttctgttcg tgaatccatg gcagtcaaat
    42121 tgccaaaaaa atatgagatc gatctaatca tggttgggca gtcaggtcta aatgcagtcg
    42181 aacgctttat gacaggaagt gtagccagct acgtgatacg tcattcacct tgtgatgtct
    42241 tgatcgtttc tgacgaagaa gaacagccaa gtaattaagc aagtggaact tgtacgacct
    42301 ttttaatcaa ttaactaaaa cagtaaaggg actgtgacaa aagtcttgtc acagtccctt
    42361 gttacgaata aatggtgttc cagaagaggc ttcttcggaa ataaagcatg aaaaaaattt
    42421 catgcagtga atgcaatttt ttgttaagat aaatctcagc aaaggataat ggaggaaaga
    42481 acatgatttt tgcttataac aaagcacacg tcggagacac cttgatggtt attatagccg
    42541 acgataaagg aacagaaaac actgttgaac gcaaatggaa tgttgctcgg atcaaagatg
    42601 aacaaggtca agttgttgct tggaactttt tccatatctc cgatcatcta acaatcgaag
    42661 ggaacggcca agtaagctta acagatgagg aattagcgaa attgaatcga ttgatcaaag
    42721 aagcaggatt cgaagaacag cttgaagctg atcatgaacc gaagatcgtt gtcgggtacg
    42781 taaaaacatg cgtcccacat cctgattctg accatttatc gattactgag acagaagtag
    42841 acaatggtac agtattgcaa atcgtttgcg gtgcacccaa tatcgaagct ggacaaaaag
    42901 ttgtcgttgc aaaaccagga gctatgatgc cagatggaat gatgatctgg ccaggaactt
    42961 tgcgaggggt agatagctat ggaatgatct gttccgctcg tgaattgcat ttgccaaatg
    43021 ctccagcaaa aaaaggaatc ttagtattgc ctgaggatgc cgtagtcgga gaagcatttc
    43081 caaaataaag aggttgtgac aagtctttgt cacaacctct tttttattaa ttttcactat
    43141 tttgattttg ttttaatgcc gattgatcga tcgtcaattc aacagtagtt gttttttctt
    43201 tcgagccttc atagtaagtg attttgacag aatctcccac ttttttctta tacaaagcag
    43261 attgaagttc tacaccagaa gaaacttctt tgtcatcgat cttagtaatg acgtcgtatt
    43321 gtttcaatcc agctttttca gccggtgtag ctgtttggac atttgtcacg atgacaccgt
    43381 tagttacaga tgaaggaatc ttcaagattt gttcttgttg ctgagtagaa acggcagata
    43441 agtcgaccat tgtgatacct agagctggac gtgtcacttt tccgtctttt tccagttgat
    43501 tgatgatatt cactacatcg ttacttggaa tagcaaatcc cattccttct acgcttacat
    43561 tagaagtaga ttcagaagta cttgcgatct tacttgagtt gataccgata acttgtcctt
    43621 cgatattaac taaaggacca ccagaatttc cagggttgat tgctgcatct gtttggatcg
    43681 cattgatatt gactgtttcg ttcgattcat tcgtacttgt cacttgtcgg ttcaaggaag
    43741 aaatgattcc tgaagtgaca gaatttgcat attcagatcc tagtggggaa ccaatcgcaa
    43801 tcgcaggctc accaaccttc agagcacttg agtcaccaaa agaggcaact gtttcgactt
    43861 tgtctgaatt gatcttcaac accgctaaat ctgaataagc atctgttcca actaattcag
    43921 cttttacctt cgtaccgtct ttcatcaaga cttcaagacc ttgctggcca tctactacgt
    43981 gattattcgt gactacataa gcagtattcc cgtctttttt gtagatcacg ccgcttcctt
    44041 cactataagc ttccaaatta ctatcatctg agctgctact ttcttcttgc tgcccgaata
    44101 gtccgccaaa accgcttgat tggttttgac tttgtaagtt gataacagaa acgacagcgt
    44161 cttgaacttt atctaccgct ttggtgatat cagaatctac attgactttg acattttcca
    44221 caactgtttc accggcagaa ttctgattgc cgcttgtagc agtagaacta ttgttgccag
    44281 tgcccatcgc tgcataaaaa atgccagctg tcagtagtcc tccaacgatc cctccaacaa
    44341 gccccagacc taacttacgc cagaggctat tatttttact ttttttcatc tttggtgtca
    44401 cattttttct atccatgtgt tcctcctcca attacattca tttatctact gttagtatag
    44461 tcttatttgt tgactttagt ctactttgag actgtgaact ttttatgaaa aactttagga
    44521 aaaatcattg ttttcagatg aaaatatttg attttctttt tccacagata ctgtgtaaaa
    44581 ctacgcggat aggattggaa aaataaggga taaaacatat ccacagcctg tgtataaagt
    44641 ggataaattc ttataaaacg tatgtttgcc taatgaatgt gatgaaataa ggtaaaataa
    44701 cactgttttc tgtggataaa cctgtggatg ttgtgcataa ctgttgggga aatcttttta
    44761 acaaaaatag ccaaaataaa catatagacg aaaaaattga ttataataaa caaagtgagc
    44821 atgaagacca aaggagagaa aacatgaata tcaaaattat ctcagtagga aaattaaaag
    44881 aaaaatacct gatccaaggt atcaatgagt atgtcaaacg gctgaatgcc tatgcaaaaa
    44941 tcgaattgat cgaagttcct gacgaaaaag ccccggagaa tttaagcgaa gcgcaaatga
    45001 gacaagtaaa agaaaaagaa ggggaacgga tcttagcgaa aatcaaagaa caagaatacg
    45061 tctatgcctt agcaattgaa gggaaaaatc ctacaagtga atcttttgct aaacaaatcg
    45121 accaattagg tatccaagga aaaagccacc ttgtttttgt tatcggcggc tctttaggac
    45181 tcagcgaagc cgtcatgaaa agaagcaatg ctcagatctc ttttggaaaa atgacgtatc
    45241 cacatcaatt gatgcgtctg atccttgtcg agcaaatcta ccgtgccttc cggatcaatg
    45301 cgggggcgcc ttatcataag tgatgcggtt tttatcattg atcctaaaaa tcttagcaag
    45361 acaaaaagta cgtaagaaag taaagactaa atacttcgga ggaacaaatg aataacaatg
    45421 ataggttatt gcgattgcgt tatgcgattg atttgaaaga tacggatttg attaaagctt
    45481 ttgagctagg cggtgtacca ctgactaaag aagaagctca ggcggtactg accaaagtac
    45541 aggataagaa caaagataat gcagaaaata atgtgtatga aaaaaccatc aacaaccaag
    45601 tttttgacgc attcctaaat ggcctgattc tcttggcgcg tggtccgcaa aaagataagc
    45661 cgatagtaga cacgccgcaa aaaagcaagg aaatcaaata tatcaacaat gtgttgctaa
    45721 aaaaattaaa aatcgccttg tctatgacca ctgatgatat tttagacgtt tttgctgagg
    45781 cagaaatcta tccatcaaaa ggcgaaatcg gggcattttt gagaaaagaa ggccaacgaa
    45841 attttaagcc ttgcggagat aaatatatgc gtaattttct caaggggtta ggaatttata
    45901 atcggagaaa agtataaaga aatttcatga gaaatcaaaa caatggttgt tttgatgaga
    45961 gctagttttt gtatgagatt aaaatattat cttaatcgag gagctggatt ggttttatga
    46021 atgatgaata taagaatgat gaagataaga tgctttttga agagatagag aatcgatgta
    46081 ggctcaattt tgagcttcgg ggaaagatgt ctttaataca acaaaaaaag tatttagcga
    46141 ataaatcaga gtttactctg ggacatgttg aaaaattaat ctcggattgg attagtagta
    46201 gaagcgaatt tacaaaaata aaacagccga ttaaatttga catgaaaaaa cttttgttaa
    46261 ataagagtga gataggtaat agagatcaat atattagagc taaagggcaa gaaataattg
    46321 attcattagg tgaaatgagg tcatacaatt atttgtatgt aacacataga gctgatggaa
    46381 tggtcattac tgtggggaaa tcttcttcta atgatatttt tttagatgga gatctttttt
    46441 atcaactcaa tacaaatcac ttgtctggca ctgaaaatat aattttaagg acggaatatg
    46501 gcaatgaaat atttgcaaaa tatgatgaga ttttaaaaaa ttatttggac tgggcttgga
    46561 taattccggt tgagtcagga gatgctaaga aactggagag attattgggc gatgaactaa
    46621 ttaataaaaa agtaccaatt ttaaattatt attcccatag acaataaaag gctatttttc
    46681 atgataatac tagttataac tgtaaaaatg gaagaaaatc tgggaaagaa gtttttaaat
    46741 aagtgtattg ttcgatttta ataaataata agcaatacca tccgtctgtg ttgcgcaaca
    46801 tcgtactaca atgaatattt tttcacaaaa agaaaatcat ccatcgaatg aatggaaggt
    46861 tttagtatac acgaggttaa tgccccctct tttataatca gaggagtgag gttttttcta
    46921 tgaatgtttc tattttctta ttgctagtct agtttctctt acgatgaaat tgggattcta
    46981 ttccagtttt tattgatttg ctgataaaat aacttgaatg gtggatataa acatgataaa
    47041 taagagaaga ataacaaaac aaggttgtga aatgattctc aaatgaatat aatagaaaga
    47101 aaaaggagga agaatcaatg aaaatagcaa ttgcaggcgc tggcgcaatg ggaagtcgct
    47161 ttgggttaat gcttcaccaa agtgggaacg aagtattatt aatcgatggc tgggcagaac
    47221 atgtccaaca aatcaaagag catggattac aagcaaattt taatggtaaa gaggtagaag
    47281 caaaactacc aatcgttctt caatccgaag tagaaaaaga agatcaagtt gatctgatta
    47341 ttctatttac caaagcgatg cagctggaaa aaatgctgca ggatatccaa tcattaatca
    47401 aaaaagatac agaggtctta tgtctattaa atggtatcgg gcatgaagat attattgaga
    47461 aatttgtacc aatggaaaat atctatattg gaaataccat gtggacggca ggtcttgaag
    47521 gtcctggtca ggtcaaatta tttggaagtg gttcagtaga attacaaaat ttaggtgatg
    47581 gaaaagaagc agctgcaaaa aaattagcag acaaattgtc tgaatcagga ttaaatgctc
    47641 atttttctga caatattcac tattctattt atcgcaaagc atgtgtgaac ggaacaatga
    47701 acggactatg cacaatctta gacgttaata tggctgagct aggaaaaaca tcgactgctc
    47761 ataaaatggt ggcgacgatt gtcaatgagt ttgccaaagt agcagcagta gagaagattg
    47821 aactagatgt cccagaagtc attgcacatt gtgaatcttg ttttgacccg gaaacaattg
    47881 ggttacatta tccttcaatg tatcaagact tgattaagaa ccatcgatta acagaaatcg
    47941 attatatcaa tggcgcaatt tctagaaaag ggaagaaata tggtgttgcg acgccttatt
    48001 gtgatttctt gactgagctt gtccatgcaa aagaagatag tttgaacgta aaataaagga
    48061 gagattgaat ggaaacttca caaaaaatat caccgaaaat ttttctgaat aaagtcctcg
    48121 ctggtacagc aacaggaatc attattggat tgattcctaa tgcagtatta ggtgccattt
    48181 taaaatattt tagtgcgtat ccctttgcgg taacgatcgc acagttagca gttatttttc
    48241 aactagcaac acctttgatc attggtggtt tgattgcctt acaatttgga tttgatccga
    48301 tgagaatgat ggttgtagcc ggagcttctt ttgttggttc tggtgtagtc aaattcacac
    48361 ctgatttggg tgaaacgggt gtttacgttg gtgctggtac aggcgatatt attaatacga
    48421 tgctgacagc atcgattgct gtcgggctga ttttactgat tggaaatagt tttgggtcag
    48481 tgtcgattgt gttaacaccg attgttgtag gtgtaggtgc aggtttactt ggtttttatt
    48541 tattcccttt tgtaacagca attacttctg caattggatc attgattaat aacttcacta
    48601 ccttacaacc gctgttaatg tctatcttga ttggttgttc ctttgccttt ttgattatct
    48661 ctcctatttc aacagtagca atcggaatgg caatccaact agatggtgtt tctgctggtg
    48721 cggctgcgat gggcgtagct gcaaccactt ttgttttagt agtgaactct tggaaggtta
    48781 ataagtcagg tgtgacaatt gcgattgctt taggcgctat gaagatgatg atgcctaatc
    48841 tatttagaaa acctgtgatt cttattcctt gtttagttag tgcagtgatt acagctattc
    48901 ctgtcgctct attttctatt tcaggtacgc ctgcttctgc tggtttcggc gtggtcggac
    48961 ttgttggtcc gttggcttct ttagatgcag ggctaaatgg ctttcttgtt gttctttgtt
    49021 ggttagtcat ccctgttttt gcggcactaa ttactcaatt tttatgcgag aaagtattta
    49081 aactgtatga tcgagaagaa gtcttcaaat ttttaggcta gtagatttta ctaagaaatt
    49141 ttcaatcaat ggatgcgtaa gtgagatgtc aacaacatct gacttacgtt tttttgcctt
    49201 tttgagtagg agattgatgc tgacaactga actcttcagt gccattcgat tttttaaaat
    49261 gtagaagaaa ctcaccttta tgttattgat tgttcaaaag gcaactagaa taaaaatatg
    49321 tgttaaaatg agaaaaaatt tgattgttgg atgtatcgaa taatcactaa aaagtaggag
    49381 aagaaaatga tttttttgca aaaatatggt ttttattttt tattattagg tgtgattagt
    49441 gatttatcga caccgtatat ccttggcctt ttttatccca aactgaatca aatgactacc
    49501 gtaattagtg tgtttggtga cgtagatagt ccagtcagac gtgctttctt ggtctggtca
    49561 gttgtatctg gacttttttt tgttctttcg ttgcctgcgt tgtatcacct atttattgga
    49621 acatcaaaaa cacttgcaat acttgctgtt gcaacagttg gtttatatgg gataggtgat
    49681 tgtattttta ctgggttatt cagtatcaat acgaatgaaa gctcttggaa tctatcgact
    49741 tggatccata atataggttc tgggctaggc tatgcaggct ttctactttt cccattgtta
    49801 cttgttctgc tttatcgtca aagtggtcaa ggtacgctta gccattttta tcttgtttta
    49861 acagttatta gtttactaat tgcaggtctt tacggattag cacggattcc gtcgattagt
    49921 cagtttgcct tctttaagca attgggcttc tttcaacgct taagtttttt ctttaactat
    49981 ttgccgatga tttgtttaag tttttttcaa ctacgaaagt agaaaaagca gtgtgaagct
    50041 gattaagtaa aagaatttct ctatgggtaa ccattcgtgt ggatgtgttc gactaagaat
    50101 agagatgagg agagcgaaaa gcaagttagt cttaacttgt tatgcgttgt gctaaatttc
    50161 aggtagtcat tttttgaatg aataagaaga aaacttgaaa gagggtgact tcatgttaga
    50221 tgtggagcag atggaaatag acctttataa tattatttta aatcgaaata caagagaatg
    50281 ggaaagaaca caatttgaag aggcaaaaga agacctagca aaaatgtcga taaagcaggt
    50341 gatagaaaaa ctagaggtca acttgcgtcc gctagcacta cgagataatt tgacaccaga
    50401 tgcgatggat ttttatttaa gaatcacagg ggagtcagcg agtgcaaagg cttatgatta
    50461 tgccaaacat aagataactt cacccttata ccaagaacgg gcgatttttg ccggtggctg
    50521 tttctggtgt atggttgagc cttttgaaac aaaaccaggt gtaatctcag tgttatctgg
    50581 ttatacaggt ggagagacca aaaaaccaaa ttacgatcaa gtcagtggtg gatatactgg
    50641 gcatgttgaa gctgttgaga tcatatttga tacacgtcaa ataacctatg aagagctgtt
    50701 ggagatttat tggcaaattt cagaccctac agatgccttt ggtcaatttc aagatcgggg
    50761 gaaacaatat cgttcaattc tatttgttgt taatgaaaag caaaggcaat tggctgaaaa
    50821 atcaagagaa caactgattc aatctaaccg atttagccgt cctatcgtta cagagattcg
    50881 ccaagcaaag actttttggc cagctgaaaa tcatcatcaa caattttatc agaagcaacc
    50941 taaaagatat aaaaagatca agcattcgca tcagcttcat ttattttttc agcgacatag
    51001 atagaggaag gttgtggcgc aaagcgttca gctccgacaa aataatgagc aactgacaaa
    51061 aatagctttt catatttttg gacagttatg aattatttcg aggagttgct ttgagaacac
    51121 cgaggaaaag gttgtggcgc aaagcattca gcttcaagtc gcaaggaaac aggaggtatg
    51181 acaagtcttt tgtcacaact cctgtttttt tactagcctt tatttccatg tgaaagagaa
    51241 ttcgaattgt agaatcttga tttttctatg gaattttgta gagaatcatc ttgataatta
    51301 atagacacct aatcgaattc cacattaatg atgaactaaa ttccgtataa aagcgcaaac
    51361 aataactata a
//
LOCUS       DAYYEF010000015        47220 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000015 DAYYEF010000000
VERSION     DAYYEF010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.015"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..1258)
                     /locus_tag="ACHA1B_001023"
     CDS             complement(26..1258)
                     /locus_tag="ACHA1B_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFM8701803.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1512..2081
                     /locus_tag="ACHA1B_001024"
     CDS             1512..2081
                     /locus_tag="ACHA1B_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8701804.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2259..2699)
                     /locus_tag="ACHA1B_001025"
     CDS             complement(2259..2699)
                     /locus_tag="ACHA1B_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFM8701805.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2857..3621
                     /gene="map"
                     /locus_tag="ACHA1B_001026"
     CDS             2857..3621
                     /gene="map"
                     /locus_tag="ACHA1B_001026"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFM8701806.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3653..4576
                     /locus_tag="ACHA1B_001027"
     CDS             3653..4576
                     /locus_tag="ACHA1B_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFM8701807.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4801..5040)
                     /locus_tag="ACHA1B_001028"
     CDS             complement(4801..5040)
                     /locus_tag="ACHA1B_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8701808.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5045..5464)
                     /locus_tag="ACHA1B_001029"
     CDS             complement(5045..5464)
                     /locus_tag="ACHA1B_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFM8701809.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5691..6929)
                     /gene="mef(H)"
                     /locus_tag="ACHA1B_001030"
                     /gene_synonym="mefH"
     CDS             complement(5691..6929)
                     /gene="mef(H)"
                     /locus_tag="ACHA1B_001030"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HFM8701810.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7036..7671)
                     /locus_tag="ACHA1B_001031"
     CDS             complement(7036..7671)
                     /locus_tag="ACHA1B_001031"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8701811.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(7785..7877)
                     /locus_tag="ACHA1B_001032"
                     /pseudo
     CDS             complement(7785..7877)
                     /locus_tag="ACHA1B_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(8013..8648)
                     /locus_tag="ACHA1B_001033"
     CDS             complement(8013..8648)
                     /locus_tag="ACHA1B_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8701812.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9160..10302
                     /locus_tag="ACHA1B_001034"
     CDS             9160..10302
                     /locus_tag="ACHA1B_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFM8701813.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10295..10501
                     /locus_tag="ACHA1B_001035"
     CDS             10295..10501
                     /locus_tag="ACHA1B_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFM8701814.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10580..11773
                     /locus_tag="ACHA1B_001036"
     CDS             10580..11773
                     /locus_tag="ACHA1B_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8701815.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11978..13117
                     /locus_tag="ACHA1B_001037"
     CDS             11978..13117
                     /locus_tag="ACHA1B_001037"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFM8701816.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13110..13910
                     /locus_tag="ACHA1B_001038"
     CDS             13110..13910
                     /locus_tag="ACHA1B_001038"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFM8701817.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13910..14737
                     /locus_tag="ACHA1B_001039"
     CDS             13910..14737
                     /locus_tag="ACHA1B_001039"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFM8701818.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14742..15449
                     /locus_tag="ACHA1B_001040"
     CDS             14742..15449
                     /locus_tag="ACHA1B_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM8701819.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            15549..16415
                     /gene="rfbA"
                     /locus_tag="ACHA1B_001041"
     CDS             15549..16415
                     /gene="rfbA"
                     /locus_tag="ACHA1B_001041"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFM8701820.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16429..17001
                     /gene="rfbC"
                     /locus_tag="ACHA1B_001042"
     CDS             16429..17001
                     /gene="rfbC"
                     /locus_tag="ACHA1B_001042"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFM8701821.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17023..18051
                     /gene="rfbB"
                     /locus_tag="ACHA1B_001043"
     CDS             17023..18051
                     /gene="rfbB"
                     /locus_tag="ACHA1B_001043"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFM8701822.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18149..19000
                     /gene="rfbD"
                     /locus_tag="ACHA1B_001044"
     CDS             18149..19000
                     /gene="rfbD"
                     /locus_tag="ACHA1B_001044"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFM8701823.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19034..21067
                     /locus_tag="ACHA1B_001045"
     CDS             19034..21067
                     /locus_tag="ACHA1B_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701824.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21111..22391
                     /locus_tag="ACHA1B_001046"
     CDS             21111..22391
                     /locus_tag="ACHA1B_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFM8701825.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22601..23407
                     /locus_tag="ACHA1B_001047"
     CDS             22601..23407
                     /locus_tag="ACHA1B_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8701826.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23419..24639
                     /locus_tag="ACHA1B_001048"
     CDS             23419..24639
                     /locus_tag="ACHA1B_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8701827.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24629..26215
                     /locus_tag="ACHA1B_001049"
     CDS             24629..26215
                     /locus_tag="ACHA1B_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM8701828.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26254..28392
                     /locus_tag="ACHA1B_001050"
     CDS             26254..28392
                     /locus_tag="ACHA1B_001050"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM8701829.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28760..29743)
                     /locus_tag="ACHA1B_001051"
     CDS             complement(28760..29743)
                     /locus_tag="ACHA1B_001051"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFM8701830.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30121..31512
                     /locus_tag="ACHA1B_001052"
     CDS             30121..31512
                     /locus_tag="ACHA1B_001052"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HFM8701831.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31528..32568
                     /locus_tag="ACHA1B_001053"
     CDS             31528..32568
                     /locus_tag="ACHA1B_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM8701832.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32587..33672
                     /locus_tag="ACHA1B_001054"
     CDS             32587..33672
                     /locus_tag="ACHA1B_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HFM8701833.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33705..34667
                     /locus_tag="ACHA1B_001055"
     CDS             33705..34667
                     /locus_tag="ACHA1B_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HFM8701834.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            34660..36087
                     /locus_tag="ACHA1B_001056"
     CDS             34660..36087
                     /locus_tag="ACHA1B_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008754 - O antigen ligase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HFM8701835.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            36089..37159
                     /locus_tag="ACHA1B_001057"
     CDS             36089..37159
                     /locus_tag="ACHA1B_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysialyltransferase family
                     glycosyltransferase"
                     /protein_id="HFM8701836.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            37146..38567
                     /locus_tag="ACHA1B_001058"
     CDS             37146..38567
                     /locus_tag="ACHA1B_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFM8701837.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            38580..39587
                     /locus_tag="ACHA1B_001059"
     CDS             38580..39587
                     /locus_tag="ACHA1B_001059"
                     /EC_number="4.2.1.115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050377 - UDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 4,6-dehydratase family
                     protein"
                     /protein_id="HFM8701838.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            39599..40603
                     /gene="neuB"
                     /locus_tag="ACHA1B_001060"
     CDS             39599..40603
                     /gene="neuB"
                     /locus_tag="ACHA1B_001060"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0016051 - carbohydrate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HFM8701839.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            40600..41748
                     /gene="neuC"
                     /locus_tag="ACHA1B_001061"
     CDS             40600..41748
                     /gene="neuC"
                     /locus_tag="ACHA1B_001061"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008761 - UDP-N-acetylglucosamine
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0006047 - UDP-N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase"
                     /protein_id="HFM8701840.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            41721..42398
                     /locus_tag="ACHA1B_001062"
     CDS             41721..42398
                     /locus_tag="ACHA1B_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HFM8701841.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            42349..43530
                     /locus_tag="ACHA1B_001063"
     CDS             42349..43530
                     /locus_tag="ACHA1B_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HFM8701842.1"
                     /translation="MAIQLKLRKKELILNSRILLSSPHMGGTEEKYVAKAFKDNWIAP
                     LGENVDKFEESITKYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATV
                     NPILYQGAVPVFIDSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYER
                     ILAIANQFNVPVIEDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSD
                     KKYVEHSRFLATQARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIF
                     NRYKEAFSGIDRIEMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRA
                     LWKPLHLQPVFQGVKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIF
                     K"
     gene            43543..44520
                     /locus_tag="ACHA1B_001064"
     CDS             43543..44520
                     /locus_tag="ACHA1B_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFM8701843.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            44520..45428
                     /locus_tag="ACHA1B_001065"
     CDS             44520..45428
                     /locus_tag="ACHA1B_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HFM8701844.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            45429..46181
                     /locus_tag="ACHA1B_001066"
     CDS             45429..46181
                     /locus_tag="ACHA1B_001066"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HFM8701845.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            46186..47133
                     /locus_tag="ACHA1B_001067"
     CDS             46186..47133
                     /locus_tag="ACHA1B_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HFM8701846.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT        15783 a         7469 c         9073 g        14895 t
ORIGIN      
        1 tttttgcatg tgtgcgaaag tatactcaag cccaatcgcc atttcggaaa atcggtactg
       61 tagagccatc ttcacggatt ccgtcgatat ccatcttgtc agatcctacc atgaaatcta
      121 cgtgggtttg acttctattc aatccagctt ctgctaattc ttcatcggac atttctgtac
      181 cgcctttcac actgaaggca taagcagaac ctagtgctaa gtgattcgat gcgttttcat
      241 caaataatgt attgaaaaag atgatgccag attgagaaat aggtgaaggg tcaggtacaa
      301 gtgcgacttc tcctaaacga cgcgcacctt catctgtatc aagcagtttt gctaagacat
      361 cttctccttg ttcggcagaa aaatcaacaa cttttccatc tttaaaagta aatttcatac
      421 ccgagatgat ggtgccagca taactcagtg gctttgtact tgaaatgtaa ccatctactc
      481 gatgactgtc aggtgctgtg aacacttctt ccgtcggcat atttgccatg aatttttctc
      541 cacgagcatt atagcttcca gcgccttccc aaagatggtt tttaggcaat ccgataatga
      601 tatctgtacc gggagcagta tagtgaaggg cagaaaattg ttctcgattc aattcttctg
      661 ctttttttgc taatttttca tcatgcttct tccatgctaa gacagggtct tcttcataga
      721 cacgagtcgt tttgaaaatc tgatcccata atgcctcaac ttgtttttct tctggcagtt
      781 ctgggaagac ttttgctgcc cattgtttac cagccgcagc cacgacagtc caactgactt
      841 tatttgcttg agttgccttg cgtaaattca ttagtgcttt gccattcgct gattgataag
      901 acgctactcg atggctatct acaccagcaa atgcatcggg atcggcagaa acaacgctga
      961 tcctgcttgc tcctttttca agccattcat ccgcttgatc gattttagat tgtggtacat
     1021 tctcaatacg atccgttgca gcatgtaaaa gaaattctct ttggatctgg tcgtcagtcc
     1081 attgaacgat aacctcagcg gctcctagtt tataagcttc ttgtgtgatc aatcgagcaa
     1141 ggggtgcctg ttccacgctg atctgtaaaa caactgtgtg tcctttttct gtggctacgc
     1201 cagtttctgc aattaagcgt gcatattttt ttagaagttc attaaaatca gataacataa
     1261 taaaaattcc tcctcaccat tttttctggt aactattagc atgataccat ttaattatga
     1321 ttcaaacaat gaggctttaa ataaaaaaag gaggttattt ttttaaggtt aagtttcatg
     1381 atatatgtta ctacttgcta tttcagcttg tgaagaaaat caaaaactaa ttttgcatat
     1441 caaaaaaaca tgttacaatg aaattaatca atggtggaag cgttataaaa aaattaagga
     1501 gattaaaaaa tatggcaaga aaaaagacga ttactagaga acagattttg gcagctgctt
     1561 atgaagtagc tgccaccgat ggatttacac gatttactgc gagaaacatc gcgaacaaaa
     1621 tgaattgttc cacgcaaccg atttatcttg agtttaaaaa tatggatgac ttgagacaag
     1681 ctctttttga gcagatctat gatcatttac aatatgaagt gttcactgtt gagcatacag
     1741 ggaatacgat tatcgatctt gcttttaatt atatccattt tgcaagaaga gagaagaagt
     1801 tgtatcgttc actgtactta gaagaatatg gtggaggaaa agagatgcag aatttctctt
     1861 atacttactt tgtgaataca gtgaaacgcg atccagctta tgtgaatctt tcagaagagc
     1921 agatcgaatc tttgtataat gggacatgga tcatagctac tgggatcgca gctttgatgt
     1981 cttcaagcat catccatcca actgatgaac agattgaaaa gatgatccaa gacagtatag
     2041 atgctatctt gaaattcaaa gaaccaatcg aaatcgattg aatatactca aaagttccac
     2101 aaatcagtag gtaacaagag atgtgtcaaa ataaggaaaa gttcgttttt cttacagcgt
     2161 atgcattttt aactcccgaa gaactcttcc atgaatgcaa tgaataaaag agccatacag
     2221 attgaataaa tctggatggc tcttttattg caagtatatt aaatttttgc gactagttct
     2281 ttagcgaaag cttctaaatt ttcgatatct tcttcttcag cattcagatc cactttaaca
     2341 ttttcggctc cttttgatgc gcctgttttt gcaaaagcag catcgaaatc atccaccgat
     2401 ttgcagaatt catcgtaaaa agtatcacca gatccgcaga caccgtaaat ttttcccaat
     2461 agatccaatt cttgcaagtc ttcataaaag tctacgatct catcaggcag atcgccatca
     2521 tcgtatgtat aagtagctac tacgcaaata tctgcctcct cgaattcatc tgcatctact
     2581 tgggtacatt cgttgatttc gacttcgata tccagatttt caaatgcttc tgcaacaata
     2641 tcggcgattt cttcagtgtt tcctgtcatg ctagcatata cgatttttgc taaagccatg
     2701 atgtgcctcc tcgtttataa ttatttaaca attatgaatt ataccaaaac atcattgaaa
     2761 agaaaataaa acctagagac acctggggaa tgtcatttgg ctaaatgtat gccgctatgt
     2821 taaaatgaga gggatttgta aaaaggagac gaaaatatga ttactttaaa atcagcacgt
     2881 gaaattgaaa tgatggcaga atctggagct ttattagcag atgtacataa aaatctgcgt
     2941 gattttataa aaccaggaat cacaagttgg gatattgagg tatttgtcag aaactatatc
     3001 gagagtcatg gcggaattgc tgcgcaaatt ggctttgaag ggtatgaata tgcgacttgt
     3061 atcagtataa atgatgaaat ttgtcatgga ttccctcgta aaaagccttt gaaaaacggt
     3121 gatttggtaa aagtcgatat gtgtatcgat ttgaaaggcg gcatttctga ttcttgttgg
     3181 gcctatgtag ttggagaatc tacacctgag atcgaccgat tgatggaagt aacgaagaaa
     3241 gctttgtaca tcggtattga gcaagcacaa gtagggaatc ggattggtga catcggtcat
     3301 gctatccaaa cttatgtaga aggcgaaaat ctagcgatcg ttcgtgattt tattggtcat
     3361 ggcgttggtc ctacgattca tgaagaacca gcagttcctc attacggaga agctggaaaa
     3421 gggttgcggt tgaaagaagg catggttatc acgatcgaac ctatggttaa taccggaact
     3481 tggaaaatga aaatggatcc taacggctgg actgcgtata caagagacgg cggactttct
     3541 tgccaatatg aacatacatt ggctattact aaagatggtc caagaatttt gacatcacaa
     3601 ggagaagaag gcacttattg atctatccag tcaataggta cgggagaggt acatgaaagt
     3661 ttggaacaaa ataaaacaaa atgaaaatct gatgcgcttt attgagacga ctcaaaagcg
     3721 catcactgat tcagaaatga gtacgacctc tgtcgtcgtt gcttattatt tactcttgtc
     3781 tttatttcca ttgattattg cttttggtaa tattttaccg tttctccaca tcgatcaaga
     3841 gactgtactg acctatttac gagaagtgat tcctgagacc gtttaccagt ttatcggtcc
     3901 tgcaatcaaa gaccttttga cacaaagttc aggaggcttg ttatccgttt ctgcattagc
     3961 ggctttatgg tctgcaagtc aaagtatcaa tgctttgcaa attgcgatga ataaagcgta
     4021 tggcgtagaa aatagaaaaa attttttgat cgtccgtttc ttctcactaa ttgtcattgt
     4081 cttgttcatg attgctatta gtggggtaac tatcgttctt gggttgggac agctgatttt
     4141 ggatgctatt cagccaatcg tacaaatacc cgtgaacttt atcgatcagt tccaaacttt
     4201 gaagtggcca atcacattgg tagctttatt tgtcatcatg ttcttgattt atttaattgt
     4261 ccctaatgct cagttgaagt tgaagacgat cattccgggc acgatcttcg ctactgtcgg
     4321 ctggatgctg ttatcacaag tgtttagtat ctatgctagg tattttgcaa cgaggatcag
     4381 cggttatcag atcataggaa gttttattgt actcatgctt tggcttaatt ttgctgctac
     4441 gatcatcatt ttgggcggaa tcatcaatgc agttgttcaa gaatacgtga cgggtcatca
     4501 aatcaaaaaa cgtcgagatc caagccgaaa atggttcaat aaattgaaaa ctaaattttc
     4561 tcataaaaaa aagtagaaac aagagttctt attgtaaatt tatatcagta atttatttga
     4621 aattttatat ctaattttca attatccgca taaacactat acattcaagc attttgaagt
     4681 atagaaaaac actcatctta ccacgaattt accacgattg aatgagcctt gatatgaccg
     4741 taaaactact aagggagata gcacgaaact gtgtatctcc cgattttttt atacagttga
     4801 ttacttcact ccgatttcaa atttcaatat tgctttcatc atgtctgtat gaatttctcc
     4861 ttttagttct tcatcaacct gcataatgat tttaccactt tcagagtggt aaaaaggacg
     4921 caagcataat ttagaaatat aaccgtcata aaacttcaaa atctctttaa ctgccatttc
     4981 atctccgctt gacgctttgc aaatcaattc aaaagaggga tagccataat ctttactcat
     5041 ttctttactt cctttcgctc aaaagcattt ttaacttcct tagtcctcta gttcttctac
     5101 tgcaaatagc agaacgtgat acatggtaca gttctgaaat ttctctgtcg ttcattcctt
     5161 gaaaataacg taataaaatc gcactacgct gtttttctga cagtctatgt aaaactgtac
     5221 caagtgtttc atcagataca taaattgtaa agtgcaagac tttaaatgat acacaatcat
     5281 aaaaacaggt atcaatcgtt ccacgttcaa cttgtttcgt ttcggctatt tcacaaaaca
     5341 atacttcacg tttagaatgt cttgcaagct gtctgtttcg acttttcact ttgttcttaa
     5401 tgacaatcag cattaaagaa ttgaactgta atctgacgat atgctcgaaa gaagatgtcc
     5461 tcataatctc accccctttc tgctaatgct gaaatatata aacggaatac cgtttatacc
     5521 ctttagaaat acagaaaaat ggtaagaaaa aagcccacac aaaacatata tttgtgcgag
     5581 ccttaaatac tgcaatatta ctctttcttt tataacacta tccttttagc agatttcaaa
     5641 ttttctttta tatattgttt ttagcctaac atactattta accccttgta ttatatctct
     5701 aacttttgaa aaattctttt tgaatatatt gaaatcatga ttgaagcaat agaagctaca
     5761 aacataacaa cccatgtttc ttgtataaat acatcgaata aaataccgta aaccatttgt
     5821 ccaataggtt gaccgcacat agcaactgct accagcgtag ccattatctt tcctactaat
     5881 tgcggtggtg tttgtgtctg aacaagagtg taaatttgaa caacaaacat agtagataca
     5941 cccatagcca caaagcacat cactgtaact acccagtagg aaactattgc aggcaattct
     6001 aaaaatagcg aaattcccat aagtaaaaca gaaacagaac aaataagtaa caaggtataa
     6061 aggtttttta gttttaactt tgaagcaaca agagctgtta aaataccacc acataaacca
     6121 cctaatgata atgctgattg tgaaaaacca tatagtgtat ctggcatttt taaaacttca
     6181 gaaattaaga taggcagacc aacaattaaa acagcactta aaaccaaatt gaaaatgcaa
     6241 accaaaaaga ttacggatat aaaaatgggt ttctcctttt tcaaaaaggt ataactatct
     6301 tttaaatcgt ttttagcaac tgcaattaca cctacttcac gaggtctttt ttggtgtgga
     6361 atatggataa aaatttccat aatggctgaa aaagtaaaac atataatact aacaattaaa
     6421 atgggattga taccataaaa ttgaaaaact actccgctta tagctggtcc gataaagttt
     6481 gctaaagtat ttacttgatt tattatagca ttaccgacgg taagtttatc tgatgatacc
     6541 aatagaggaa tacttgcttg taccgctggt tgatatgcac cagaaatacc ataaagtaac
     6601 atcaaagcaa caataaacaa aggtatgata ggaatttttc ccaatgacaa ataaaatact
     6661 aaaattatga ttgctgttac aaaatctagt atgaccataa tgtttctttt atttgtcctg
     6721 tcagcaataa taccacctac cagcgacaaa ataaccatag gtaaaaaaga gcaggctgta
     6781 gcaataccaa acaaagctga tgaaccagtt tcttttaaca aatagtacgg taatgcaaat
     6841 cgtaggatag cgtttccaaa taaagaaatt atctgtccta taacaacaag tataaaatca
     6901 cgattaaaaa gttttttttc tgcttgcata aaatctctcc tttttattta atcaaacaga
     6961 ccgtcggttt atataatggt ttaaataaac tgctctttta tagagcagtc tatcgtatag
     7021 ggataacaaa tacagttatt tacaaaactg tataaatgca gaaattgttt cttcgtctaa
     7081 taatgtgtct atgcctattc catttaaaag ggcattgaat gtattgcaac gtttttccat
     7141 accctcttta tccgtcattt caactaatgg gttgagccat acattactta ataccatgat
     7201 aacttctgca atttcatgtg aattttcaat ctccaaagac ttatccttga taccttgttc
     7261 taaaacgggt tcaacaaatt caggtactac aatttcatac atttgttcta tttgcatagc
     7321 aagaaaacga ggattgttta atagttgagg agaaactgtc aataaaacgc tttggttaga
     7381 attgaatacc gctgtcttaa atatttctct taacttttct aaaccgttta aactatcgtt
     7441 atctctaatt ttagcaaata ttactgcatt ttcatttcca attctttgaa aaattgcttt
     7501 taaaatatct tcctttgaat cgaaatgatg ataaatagca cctttagaaa gttttgtttc
     7561 attgataata tcttgcaatg atgtgttatc atatcctttt tcacaaaaca tttttgtaga
     7621 aacatctaaa atgagtttta ctgtttcttc tggatattta tttcgtgcca taacttacct
     7681 ccaatacaaa ccgttggtct gattaaagta tatcttagta ttttatgctt gtcaatataa
     7741 agacttgcaa ttttataaaa atgcagaatg caagcctttt tcatttattc tacaatcttc
     7801 cagttgcttt ccttatgcgg tgtcaattca tactgtgata cctgcgttgc ctttgcctga
     7861 tttaccacaa atcagatttt atccctttct tcctcttgat tgcccacaac agaaaagaaa
     7921 aagccctgtc aagagctttg ccaccattgg tggtgctttg cactcttgat cgggcttttt
     7981 gtttgctgta tcttctcgca agaggaaaaa agttactcgt cctcatcatc aaaattgtta
     8041 ttccttaata cttctcgtaa cagttccata tcttcttttg agttcgggtt tatcattttc
     8101 acgacttgat aaggtgtctt atacttatgt ccctctatgc tttccccaaa catatccata
     8161 ctgtataaat catcatagcg gtctaataat ttttgaaact tcaaatgctg gataaattct
     8221 ttgattgggt aaaggtcgga cgcttcaatg cttttcccgt tgatatagtc tgtaatatat
     8281 tcccgtaact tttctaactc atattccagc cattcttcct cgctgtcaaa gaagttatca
     8341 tagtgtccat gtttcagttc tgcatttaga cgttcttcgg ctcttaaaaa ctgacagact
     8401 tccttttcag attgattgac atacttccat tctcccgaca acaattcatt gggcgtaacg
     8461 tccagcactt ccattatctt ttccagcgtt tcataggcag gatagttcaa ccctctttca
     8521 atcttggaaa ggctctgcat attgataccg attttgtccg caagttcctg ttgtttcatt
     8581 cccctaaatt ttcttatggt ctgtatatta tttcctaaat ggcttatttt cattgcataa
     8641 ccctccatat ctcgttatat cttcgctatt ataagtctat catgcttaat atgatttgta
     8701 aaggcaaaaa aagatattga caaataagca tataagaatt actatgttct tgtaatcgaa
     8761 taagcacaat agaatgaaat ataaaaacat tcaaaaagaa atacctatct gattaaatcc
     8821 gtagatatga atatcggttg aaatggaact tgttagaaaa ggcaaaacag aacttgctga
     8881 caaagtattt ctgacacggt ggcggaagcc tctcaggctt accgccatga caccttgtgt
     8941 caaggggaag aaatgctttg tcggctggcg agcctgcgag ccttgtctgt gcccccgtta
     9001 tctaacaggg gggcactatt tcacaaaaga caagtcaaaa accatacacc cccaaacctg
     9061 tgagtagtaa tgagaggttt taagaagata gtacatatca cactttttga aaggtggttt
     9121 acaggtattt caaggctatt gtgggattgg aggaatacaa tgaacaattt agaatttgca
     9181 cttgaaatga agaacaaacg tcttgccagc ggtctttcac aaggagaact tgcaagtctt
     9241 acccatgtat caagatatag tatcaaccgc tttgagaacg gaaaagctaa cgccagcaag
     9301 gaaacacaga acattatcct gcgttgtctg aattactata tctgcgataa gcctttttat
     9361 ctgctcgttg attatctgtc tgtccgtttt ccaacgactg acgcattgga agttatccga
     9421 aaggtgcttg gcatgaaagc agattatttt atccattatg actatgggta ttatggctat
     9481 aaggagcatt atgcttacgg ggaaatcaag gtcatggctt ctgatgatga acacatgggc
     9541 gtatttttag aattaaaagg ggcaggctca cgcaacatgg aatatgtctt acaggcacag
     9601 aacagggact ggtattcatt cttaaaccgc tgtcttgact gtggcggtgt tatccgacgt
     9661 tttgacttgg caatcaatga tatgtgcggt ctgctggata ttcctgtgct atctgaaaaa
     9721 tacagaaatg gtggtgcgga atgtcgctgt aaaaactatg aaaatgtaca aggtggaaaa
     9781 ttaagcggaa aaaaccgtaa tttagcaagt accctttata tcggctcaaa ggcaagcaca
     9841 aaatatttct gcctgtatga aaaacaaaag gaacaggcaa cgaaaaagaa acataccgat
     9901 attatcaacc gttttgaaat tcgtctgcgt gacaaaaagg cggtacaggc agttgaagaa
     9961 ctgttattga cgtataaccc tcatgggctg gtgttttatc tcattaccga ttttgtggaa
    10021 tttcctgact atccattgtg ggagatattc atttcccatg acagtttacc ttttgaaatg
    10081 aaccctgtac ctgtcaatat ggaacgcact ctgcaatggc tggaaagaca ggtcatgccg
    10141 tcaatcgtga tgatagagga aatcgacagg ctgacaggtt caaactacat gaaaatgatt
    10201 gatgaatgta cccacctttc tgaaaaacag gaaatgcttg tggaacagat gtgtacggac
    10261 atatcagacg taatcgaaag tgagggggtg ttttatgagt aatacacagg atattcccgt
    10321 atgggaaaaa tacaccctta ccattgaaga agcgtcaaag tatttccgca ttggagaaaa
    10381 caagttaaga cgattggcag aggaaaacaa ggacgctggc tggctcatta tgaatggcaa
    10441 ccgcatacag attaaacgcc gacagtttga aaaggttatt gataaattgg acgcaatcta
    10501 atgcaaatga gccttgtatg tgttatgatg aacacaagtc atatcaaggc tctttccaac
    10561 aaggaaagga gcagacacca tgaaagaaaa aagacgggat aacaaaggtc gtatcctgca
    10621 tactggagag agccaacgaa cagacggaaa atacttatat aaatatgtag acgcattggg
    10681 aaacacaaaa tatgtgtatg cttggagatt gacacccaca gacccgacac caaagggaaa
    10741 acgggaaaaa ccctcacttc gagaactgga acagcagata agacgggata ttgaggacgg
    10801 tatcgacagc acaggcaaga aaatgacgct ttgccaactc tatgccaaac agaacgcaca
    10861 gaggacaaat gtgaagaaaa gcacacagaa acaacgggaa caactcatgc ggttattaaa
    10921 agaggacaag ttaggtgcta ggagcattga tacgataaaa ccctctgacg ctaaagaatg
    10981 ggcgttacgc atgaaagaca aaggcttttc ctacaatacc attaacaacc ataaacgctc
    11041 gttaaaagcg tcattctaca tagccataca agatgattat gtgaggaaaa acccttttga
    11101 tttcaagcta agtgaagtca tagaaaatga taccaaagag aaagtcgcat tgacagagga
    11161 acaggagcaa gccttattgt catttattaa gacggacaac gtgtatcaca agcattatga
    11221 tgatgtgctg atactgttaa agacaggact tcgtatctcg gaactgtgcg gactgacagt
    11281 agccgacatt gatttcaaga atgaagttgt gattatcgac caccagttac taaagagtaa
    11341 ggaacagggc tattatattg aaacgcctaa gacgaaaagc gggataaggc aagtgccatt
    11401 aagcaaagaa acgatacagg catttcaacg ggttatcaac agccgaccaa agataaagtc
    11461 gatagaggta gacggacaca gcggttttgt gtttatcaat ccgaaaggta atccaaaagt
    11521 tgccattgat tataacgcct tatttatccg tatggtaaag aaatacaaca agcaccacaa
    11581 ggacaatccc ttgccacata ttacaccgca tacgctacgc catacattct gcacaaggct
    11641 ggcaagcaag aacatgaacc cgaaagattt acagtatatc atggggcatt caaacatcag
    11701 tatcacaatg aactggtacg ctcatgcgtc catagatacc gcaaaatcag aggttcagcg
    11761 tctaatcgca tagaagtatt taccacgatt ttaaccacga ttgacaggga aaatataaga
    11821 agatagacct agatatgcga ggtttaccac aaaagcaaaa tgcccgtaga gccgataaaa
    11881 taaggctttg cggacatttg agaagatata aaaagatagt caaaaagaca tatataattt
    11941 ataataatta tgactcttaa ttaaagtagg tgcccatatg cttgtttctt ttagtatggt
    12001 tataagattt tttctgacaa ttttattatc actgatatta acacctgtat tcaaaatcat
    12061 ttcagtacaa acaggtatgg tcgacaaacc aaatgaaaga agaataaata aagttccaat
    12121 gccttcagcg ggcggactgc ctatctttat ttcatttgtt atatcgactt tattcttatt
    12181 ccgtaaaatt atccctcaat cgtatattgt accgatcttg attgcttctt tagtaatcat
    12241 agtcacagga gtgctcgatg ataaatatga gctgacacct aaacaaaaaa gtatagggat
    12301 cttgattgct tctcttatta tttattttgt agcagatata cgtattgatt ccttcacgct
    12361 tccttttatt ggatatatcc aactaggctg gcttagtttt cccgtaacga ttttttggat
    12421 cttcggtatc acgaatgcgg tcaatctgat tgacggtttg gatgggctgg cggcagggat
    12481 ttcattgatc ggtttaatta cgataggaat cattggatat tttttcctcc atgcttctac
    12541 agtgtatatt ccagttgtta ttttctgtct tgtagcaagt attatcggtt tttttcctta
    12601 caatttttat ccggcaaaga tttatttagg cgatacagga gctctattcc tagggtttat
    12661 gatggccgtc ctttcactac aagggctgaa gaacgtgact tttgtttcat cgatttcttt
    12721 gctgatcgtc atgggagtgc cggtaacaga cacgtttttt gctatcatta ggagaaaagc
    12781 aaaccgtgtt tctttttcta cagcagataa aaaacatctt catcaccgac taatcagttt
    12841 aggctttact cataaaggtg ctgtcctgac gatttatgcg atggctttga tgttttcttt
    12901 cacagctatg gtcatgaatt atactggaag aatcggaacg atcatattga ttattgccat
    12961 gttgtttgct gcaattttat tatttgaatt gattggtctg atcaatgaga aacatcagtt
    13021 tattttaaaa acattgcgat ttttagggaa taaagagtac cgtacgcaag taaaacagaa
    13081 atatttgaag aaatggaacc gtcatataga tgaataacaa attaaaccag ccgatcctta
    13141 ttagtattgt gacggcaaac agtgataaaa tttttcggac actagataat tttatttcaa
    13201 ctgtaaaaga tgaaacagca gtaaaaatcc gaatttttga caacaattca cttcccgagt
    13261 acaaaaaaag actaacagag tataggaaat atccctacat cgatatctat tttcatgatg
    13321 aaaattccgg atttggttat ggacataatc acaatctgat agctagcgat tctcgctatg
    13381 gcattatttg taacccagat attttagtgg atgaagagac agttacagca ttggtcttgt
    13441 tattgaaaga acatccggaa tgtgcgatgt tagcacctaa gattcttaat gaagatggaa
    13501 caactcagca cctcatccgt gagcagctgg ctgtttttga ttacgttttg cgctttgtgc
    13561 ctttcaaatg ggtcaaaaaa aagtttgaca aacgactggc tgtgtttgaa tgccgaggat
    13621 tgcctactga tgctaatagt tatgtacgga tgatctcagg tagttttatg gtagctgata
    13681 ttgataaatt taaagagata aaggggtttg atgagcgttt cttcatgtac tttgaagaca
    13741 acgacttgtg tttgagtttt gaaaaagcag gttacaagtt attgtacaca cccttttatg
    13801 cagttatcca tttttacggg aagggtgcgc atcgaaatgc aaaactgttt cgcgtgtttt
    13861 tgacttctat gatgaaattt ttcaataagt gggggtggcg ttttttctga tgaaaccaga
    13921 aatattagta gtcgttgtgc tttatcagca actattcagt caatctccag cttatggacc
    13981 attaagcaaa gcacttagcg aaaagcaaat tcagcttatt atttacgata atagtcctca
    14041 aaggcagcaa aatgagctgt ttgaaaaaga aaatatcgtt tatcatcatg atccgcaaaa
    14101 tcctggttta gcggtggctt ataattttgc gttgtctcaa gcagatgaag gaacacgttg
    14161 tctcgtcact ctggatcagg atacgaggct agtcgacgat tattttgaac tattgcgtaa
    14221 agtaaccttt acagatgaat gtgttgctgc agttccgatg attttttctg ggagccgaca
    14281 agtttctccc ctatattcag atcgttatat caatcgtaca gctcaagcag tagaagttga
    14341 aggcccaaca gctgaacgaa tcatggcaat caattcaggt gttgcctggt ctgtcaaatt
    14401 tctaaaaaag attggcgggt ttaatcctgc tttttcttta gattttttgg atcattggct
    14461 gttttggaaa gtggatcagt tggaaaaaac tgtggagatc cttcctgtac gaatggaaca
    14521 tgatctttcg gttttagact atgaaaaagt ttcaagtaat cgataccgtt ctattttaca
    14581 agcagaaaat cgattttatc atgaatatga tcaaaggcat ttatccagtc accgacgaca
    14641 attattgtta agaacagcta aacagttctt gaccgtcaaa aaccggcata tctggcggat
    14701 gactttgcgc tcatatgtta agaattggaa ggtgtgaatt cgtgcgttcg gtttgtatag
    14761 ctacctttaa tggaggcaga tatttaagag agcagttaga tagtatttta tctcagcttt
    14821 cagcagaaga tgaagtagtc atttctgatg atgggtcagt agatgataca tgggatatat
    14881 taactgaata cgcagaaaaa gataagcgaa tccagctttt ttcggggcct cgtcaaggat
    14941 tgatcgctaa ttttggttat gcgatccagc agacgaaagg agatctaatc tttttggcag
    15001 accaagatga tgtttggttg gagacaaaag tgaaaaagat cactgactat tttgagcaga
    15061 atccggatca gctagtagta gtttctgatt taatcattgt ggacagcgag ctgcaagaga
    15121 tccatgattc gtatttttcg tttcgaaatt ccaaagaagg atggcttaat aatgtgataa
    15181 gaagtcacta tattggtgct ggtatggctt tccggtcttc tttaaaaccc gatattttgc
    15241 cgatcccgtc agaagtgccg atgcatgata tgtggattgg tttgctggga ggaaagaaga
    15301 ctgggttcct aagagaaccg ttaactctgt accgaagaca tgatttaaac gcgagtgaga
    15361 ttgaaacaca ttctaaatta cggcaaaaaa tttcttggcg tgttcatctg attacggcgt
    15421 tgatcaaacg aaaatggttt aaacgttgat aaaagatgtt taaatcctta atatttccat
    15481 gacaaatata acaattgatg agataataac aaagtgaaat ttgaaatcaa aaaggagagc
    15541 agatatccat gaagggaatc attcttgctg ggggcagcgg aacacgtctg taccctttaa
    15601 caaaggcaac atcgaaacaa ttgatgccga tttatgacaa accaatgatt tattatccaa
    15661 tgtctactct gatgttggcg ggaatcaaag aaattctgat tatttcaacg ccacaagata
    15721 caccacgttt caaggaatta tttggaaacg gaaatgattt aggactgcag atcgaatatg
    15781 cagtacaaga aagtccagat ggattggcac aagcgtttat cattggagaa gaatttattg
    15841 gagatgatag tgtctgcttg gtattagggg acaatattta ctatggtggc ggtctgtcta
    15901 aaatgttgca acgagcagct tcaaaagata caggcgcgac agtatttggc tatcatgtca
    15961 atgatccaga acgctttggt gtagtagaat ttgatgagaa tatgcaagct ttgtcgattg
    16021 aagaaaagcc tgctcagcca aaatcaaatt acgctgtaac tggcctttat ttttatgaca
    16081 atgaggtaat ttctatcgct aaaggtatca aaccttcaga acgtggagaa ctagagatta
    16141 cggatgtcaa taaagcatat ttggataaag gaaaactatc cgtagaactt atgggacgcg
    16201 gatttgcttg gcttgataca ggaacacatg aatcattgct tgaagcatct acctttatcg
    16261 aaacaattga aaaacgtcag aacttaaaag tggcttgttt ggaagaaatt gcttaccgta
    16321 tgggctacat cgataaggaa caattgctgg cccttgcaca gccattgaaa aaaaatcaat
    16381 acggtcaata tttattgaat ttggccgctg aataaggagt ccttacagat gaaagtaaca
    16441 gatacaaaat taacagatgt caaaatcgta gaaatggacg tctttggcga tcatcgcggt
    16501 ttcttcacag aaagttattc aaaagcaaaa tttgcagaac atggattgaa atatgacttt
    16561 gttcaagaca accattcact atcagctgaa gctggtgtcc ttcgggggct tcatttccaa
    16621 aaaggagaag ctgcacagac aaaattgatt cgggtagtca ctggagcagt tttagatgta
    16681 gtagtggata tccgcaaagg tagcccgact tatggtcaat gggacggatt tatcttatct
    16741 gaacataatc atcgacagtt gcttgtacct aaaggatatg cccatggatt cgttactttg
    16801 acaccaaatg tgaacttcct ttataagtgt gataattact ataatgcaga agcagatggg
    16861 ggcatcgcat ttgatgatcc agatttagcg attgattggc caattgatcc atcaagagcg
    16921 attatgtcgg aaaaagatca ccgtcatccg acattaaaag aatttgaagc agaaaatcca
    16981 tttgtttacg gagaaatcta agaattaagg agaaattttc ttatgaaaaa catcattgtt
    17041 accggaggtg ccggattcat cggctctaat ttcgttcatt acgtggtaaa caatcatcca
    17101 gaagtgcatg tcactgtttt ggataaactg acttatgcag gaaacaaaga gaacttggct
    17161 ggacttccta gcgatcgcgt agaattggtc gtaggagatg ttgcagatgc agaattagtg
    17221 gaccgtctag taaaagaagc ggacgcagtt gttcattacg cggcagaatc ccataacgat
    17281 aattcattaa aagatccttt cccatttgta caaacgaata tcattggtac gtatacactt
    17341 ttagaagctt gccgcaagta tgatgtacgc tatcatcacg tatctactga cgaggtttac
    17401 ggcgatcttc cattacgtga agacctgcca ggacatgggg aaggcgaagg agaaaaattc
    17461 actgcggaaa caccatataa tccttcaagt ccatattctt ctacaaaagc tggttcagat
    17521 ctgttagtaa aagcatgggt gcgttctttt ggcttacgtg caaccatttc aaactgttca
    17581 aacaactatg gtccttatca gcatattgaa aaatttattc ctcgccaagt aacgaatatc
    17641 ttaagcggta ttcgtccaaa attatatggc gaaggaaaga atgttcgtga ctggatccat
    17701 acgaatgatc attcttcagc agtgtggctg attttgacga aaggcagaat tggcgaaacc
    17761 tatctgatcg gtgcagacgg tgaagaagat aataagaccg tgatggaatt gatcttagaa
    17821 atgatgggtc aaccaaaaga tgcgtacgac catgtaaacg accgtgcagg acacgacttg
    17881 cgttatgcaa tcgattcgac aaaattacgg gaagagttag gatggaagcc tgagtttacg
    17941 aacttccgtg atgggttggc tgacacgatc aaatggtacg aagaacatga agactggtgg
    18001 aaaaaagaaa aagaggccgt tgaagcagca tatgccaaaa atggacaata atacagagaa
    18061 aatgtcactg tattaatgga aaaacacatg tgaggcaggc gctcgcctgt ctctttttta
    18121 aaataaaaat caaggagcgg ataatcatat gtttttatta actggaggaa atgggcaact
    18181 aggtacagaa ttgcgccatt tattagatga aaaaaatctg caatatgttt caacagatgc
    18241 aaaagacttg gatatcacag atgccgagaa aacaatggct tacatcacag aattaaaacc
    18301 tgatgttatt ttccattgtg cagcttacac agcagtagat aaagcagaag aagaagcaaa
    18361 agaattagat gagaagatca atgttgatgg tacaagaaat gtagcacttg cagcaaaagc
    18421 tgtgaatgct caattcgtct atatcagtac agactatgtt ttcgatggaa aaaacaaaaa
    18481 tgtagaatac gaagtagacg accaaacgaa tccactaaat gaatatggtc gtacgaaatt
    18541 attaggcgaa aaagcagtag aagagatttt agaagactat tatatcatac gaacttcttg
    18601 ggttttcggg atctatggac acaatttcgt cttcacgatg caacgcctag cggaaacccg
    18661 cgacaaactg actgtagtaa atgaccagtt tgggcgacca acttggacac gtactttggc
    18721 agaatttatg gtatatgtca tcgaagaaaa agcaccattt ggtatttatc atttgtcgaa
    18781 cgaaaatagc tgttcttggt atgaattcgc aaaagaaata ttgaaagata cagatgtaga
    18841 agttgcacct gttacgtcag aagaatttcc gcaaaaagca acacgtccgc agtattcagt
    18901 catgagcctg aaaaagacag aagagttagg atttgtcata ccaacttggc aagaagcact
    18961 tgcgcaaatg ctggaagctg ccaaaaaaat gaataagtaa tttcctttta tcaaatagaa
    19021 tttggagcat gatatggaaa aacaaacaag aagtgcacga cgaaaagaaa agccaaaagc
    19081 gaaccaggca gattcgaatt tggtgcttga cctgtttcta aaactccgct atcttattgg
    19141 cgttttagtc atcgtggtca tcgttacttt taatttaaac ggaagttcac ttggtgtttg
    19201 ggataaatat gtgtcgcaaa gagacgatgg gaaaaaaact gatgtgattt ttggacagaa
    19261 tcgggaagtg cggtcagacg aatggctggt gcagacacct ttttacctct cacaagctga
    19321 agaggacttt ccgttggtga acgaggatta ttcattaaac ggacaaaaca tgatcattgc
    19381 gtataattct cctgtaaagg atattacggt tatcggaaaa ccattcaact ggggattctt
    19441 tttcctcgga agagatcgag gactttcctt ttattgggcg atgaaattag tcgtcatggt
    19501 cttgcttgga ttcgaagtac tgatgatatt aacgaagaga aaaaaagctc tatcgctaat
    19561 cggtgcattt gcgctgacat tttctccagc agtccagtgg tggttcatgc aacatgtggg
    19621 cgatttgatt ttctttactt tgggactgat gactgctttt tatcattatt tctacaatca
    19681 tgataaaaaa tggctacgaa cgttgatgat gcttttggtg gttattttcg gtattgggtt
    19741 tattttagtg atttacccag cccatcaagt gatgctggcg tacttgctga ttttttattt
    19801 tgttggcctg cttatttact atagcaagaa agtttcatgg gatctgttgg atgtagtgtt
    19861 gattggaggg gcagttttat ttattggcgg agtcatggtt catttctggc taacgtcaaa
    19921 agacgcattg ttagcttctt tgaatacctt atatccagga aaacgggtaa gtactggagg
    19981 aaagtggacg attggcgaat ttttttcttt ccttacaaat tggaaaattc cttttgaaga
    20041 tatcaactat tcgaataact ctgaagtggc cctgttctat cacttttttc caactgtatt
    20101 cctagcaagt ccatttgtgt tatttggcaa aaaagatagc gaacaaaagt tactgggacg
    20161 tattttgatg attttttgtc tgttttctat cttttggatt accgttgggt tgccaaaatg
    20221 gctagcagaa atcactctgc tgtcttatgt tcctccatta agagccatcc ttacttttag
    20281 ttttgcggct tgtttattat cgatctggtt tatcgcttat atttggagag aagatgttat
    20341 tcctatttgg tataaattca ttttgttggc agtaaatgca tggtcttatt tctatgcgat
    20401 tacgcattcg aaaatggata attatttttc ggattttgaa accatcgcag ttgctgtgtt
    20461 gggaacagtg attttagctt ttgcattatt tggctggaga cgcttgtttt acctcgcttt
    20521 tgccgcctta gttatcgtat ctggcttttt cgtcaatcca gtcgtagaag gtacaggagc
    20581 gatttttgaa aaaacactgg caaaagaaat ccaaaaaatc gatcaacaag atcctggtaa
    20641 agtttggttg tctgaagatg aattatataa cttcacccca acattgggag tgaaatcctt
    20701 caatacagta cgcttttatc cagatatagc tgcatggaag aaaatcgatc cgaaagaaga
    20761 atacgagaag tattataatc ggtatgctca tacaagagct tttatcgcta aggaagatac
    20821 aaagttcatt ttagatcgtc cagatatgtt ttcggtcacg ttgaattttg aagacgcaga
    20881 aaaattaggg atcgactatg tgatcagtaa acgaccatta actgattaca accaattata
    20941 tgaagcgcag ttcacgcagc tatatggacc ggataaagac ggttatatga tttttaaagt
    21001 agaatatccg gattatccag atgtaccaca aacacaaact caggaaaatc agctagtcgt
    21061 acagtaatag gctagctgag aataatcctg aaatgttagt agaaaggaga gtggagataa
    21121 ttcaagcaat cgtacaaaaa tttgtcaaca aaatgagtgt cggtttcttg cttttgttac
    21181 tgacgctagt cttttttgtt tggacagcag ggttaggttt tccagcaact ttgtttatat
    21241 ataacaatag ttcattactt atcgctttta gtgtggctat tttgctcatt ttaaatgttt
    21301 ataaagcaaa aggcgtcgat tttctttatc taggtgttgc gcttgccctt ttcattttct
    21361 tttcttactt tcgggaatta agaaatgagt ctttatttgg agacttactg tttcctttga
    21421 ttattttatt ttgtttagta attaaatgga tcgagtggac aaaatgggat cgcggtattt
    21481 atctgattgt cttttcggtc ttcctcggaa tcacgttata tcgtgtattt acagagatcc
    21541 aagtaccaga aggacaaagc atctgggctc caggcaattc gctttctgat atttggatca
    21601 atacgaatat aatcggaagt tctttgatga ctcttgcttt attgatcagt ggatttgcca
    21661 gttcttttga acgatggtat gtacgaatca tcggtgcagt agcagttgtt gcagcttttc
    21721 tcgggatttg ggtctgccaa tctagaggtg cattagtcgc gttgattgtt tttgcgatat
    21781 tggatctttt acctaaatcg ttgatgcgtg tcattcgtgc gccatttatt gcttacacgg
    21841 ttacgattct tttagctttg ccgatttctt atctggcggc tgtctctgaa aaagtcaatt
    21901 tgtttaccgg tcgagaagat atttggcata aattctatca gacgctagga gaaaaatctg
    21961 aacaaatttt actaggaatg aaaacattta tcttccaacg aggaaaccaa tttttaggaa
    22021 accacaatag ttataattct attttgaata tctatggatt gataggattt gggattgctg
    22081 ctttgctgct tatccttttt attggtcgct taacgttgaa agcagattta tccaacgggc
    22141 agatgacttt tatctgggcc ttttttgcgg tgatgatgca gtcatttatg gaggatacat
    22201 tgacttcata cccatgggtt ccgattattt atatcctgtt ggctatggcc gttcatcgat
    22261 atgatgaacc agaagttgcg gaggaattct atgttatgga agaggcatat gacgatatga
    22321 cttatgatga tacatcttat gaggaacaac cagatagcgc tcattcttcc aggatccaac
    22381 gctatcattg ataggcacaa aatacgagag aggctgtgac aaccgtcgca gccttttttg
    22441 gtttattgca attgtctagc atcttctgta aaatagaaac gttagagaaa atcttgtatc
    22501 atagaaaatt aagaaagaaa taagaacgca gctcggtacc aaaaatatgg taaaatggca
    22561 cttgactgta attcactgaa aatcgcttgg aggaacacaa atgtttaaag atttgtattt
    22621 atttatgaag gacatttatc agaacagaaa attattgcta cagttttcga tcaatgactt
    22681 caaatcaaga tatgcaggat cgtttttagg aatcttatgg gcgtttatca atccgctatt
    22741 tactgtattg atttattggc tggtatttgg tgttggactg aaagcacaaa tgatcgatgc
    22801 aaaataccca tttatcgtat atttagttac cgggatgatt ccctggttct tcttctcaga
    22861 tgcatttgca tcaactacgg ttgtttttcg ggaatatact tatttagtaa agaaagtcgt
    22921 attcaatatt cgtatcttgc ccacgacgaa aatcctatcc aatctgtaca cccacttatt
    22981 cttcattctg attggcatag ctgtcgcgct tataaatggt atatatcctt cagcaatgtc
    23041 tttacagctg atttattatt tattttgcat gtgtgctttc ttgacaggat tgacttggct
    23101 gacggcatcg atccaaccat ttttacctga tatcatgcaa ttaattacga tcgtgctgca
    23161 gttgatcatg tggacattac cgatattatg gagccctaat cagtttgatt caggtcttgt
    23221 aagcatattg aaattaaatc cgctgtacta tgttgttcaa ggttatcgtg agtcattttt
    23281 aagtgaagct tggttctggg agcatggaac atatactttg tatttctggg ttttcacgtt
    23341 agtaatgttc gtaatcggct ctgcagtgtt ccgtagattg aaaccacatt tttcagatgt
    23401 gctgtaagga gaatagctat gacagaatat gcaattagac taaaagatat cacaaaatct
    23461 tataatatgt acgcaaaacc ttcggatcga tttcgtgaag ccctcaatcc ttttaagaaa
    23521 tcctatcatg atgtatttta tgcgttgaaa aacgtgaatg tagaaataaa aaaaggtgag
    23581 atgatcggtt tcgtgggaga aaacggatcg ggaaaatcta caatgttgaa aatcattacg
    23641 ggagtactga caccaacatc cggcacgatg gaaatcgaag gaaaaatctc agctttgcta
    23701 gaactaggat caggattcaa tcctgagtat tctggctatg aaaatatcta tttaaatgga
    23761 atggttctag gattttcaag agaagaagtc gatgaaatgg tcgatgatat cattgaattt
    23821 gctgacatcg gagaccatat ttatcaacct gtaaaaactt attcaagcgg gatgttcgtt
    23881 cgtctagctt ttgctgtagc aatcaatgtg aatcccgata ttttgattgt ggatgaagca
    23941 ttggcagtag gcgatcttga atttcaacta aaatgtatgg aaaaatttac agaaatcaag
    24001 aactcgggaa agacgatttt attcgtttct catgatatca gttcgattcg tcgtttttgt
    24061 gatcgttcct attggttgaa aaacggagaa gtcgtcgaat atggcgatac gatggaagta
    24121 acgacgaatt atgaaaactt tttaaagaaa aaatcagtta aaacagtgga tcggaataaa
    24181 aaccaagtag aacggttcgc cgctccagat atcgtcgacg tgacgaaagc ggaattgttg
    24241 gataaagaca aaaatccggt ggatatgctg gaacaaggag aaaaactata cgttaaagta
    24301 acttatgaag taaaagatga tacaatcaaa aatccggttt taggaattgc gctacgaaca
    24361 gtcgacaatt tttatgtatg cggacttaat actctactag atggtatcaa gattccttgg
    24421 aaaaaaggag agaatatctt ttatctggag tatgaaaagt taggtttgtt agctggtgaa
    24481 tattattttg acgttgcggt ctttgaagaa aatgcaacgg ttcctttggt atataagaca
    24541 aagtacatga acttgtttgt cagcggttct tatatcggag aaggcatcgt ggtcttagac
    24601 cataaatggg aagaagggac tcatagcaat gaaatatgat tttgaaatgg acctagatga
    24661 acaaagcagt gtgggaaaaa ttgccgcaca gatcaaacca ggaagtaaag ttttagagtt
    24721 tggtcccgga aacggccgat taacgaaaca tttaatcgga gcaaaacaat gtgaagtgag
    24781 cattgttgag ttagataagg aattgttcga ttttgtcagc gaatttgctc aagatggatt
    24841 ttatggtgat atcgaaagtt ttgagtgggc aaactattat gctggacaga catttgatta
    24901 cgtcttgttt gcggatgttt tagaacattt ggtagatcct ggaaaaacat tgaagaaagt
    24961 cagagaattt ttgaatgaag aaggagagat cctgattaca ttccctaact tggcgcataa
    25021 ttctgtcatg atcgatttgt tcaataacca attgccgtgg gcttcttatg gtctcctaga
    25081 tgaaacccat aattcttttt atactcatga tggcttccaa aaagtttttg aaaaagcggg
    25141 attattcatt aatattgaag attatttgta cttagctgta ggtgatacag aattaaaatc
    25201 aacttatgaa gaattgccgg aagctgtacg ctatgatttc aaaatgcgac catttggtga
    25261 agtctaccaa tactttttct cattgatgaa acatccagta gcacaaagtt ccattgcaga
    25321 gccacaaaat tctaattatg taaaagtgtt agaagtaacc cagcaaacga aacaagatga
    25381 aacaatccaa caaataccat tcaataattt cacaggggaa aatgagacac taagtttccc
    25441 cgtatcagaa acaacagaaa gaatggtgtt tcgcttcgcg caacaaccta gctttatcga
    25501 attcagcgca gaagctgccg gagaaaaact aacatttatc gattcgaatg ctgtagtcaa
    25561 aacagtaaat gattgttatt tgtttgatgg gaaagaatta ccagagttcg ttctaacgga
    25621 tatttctggg aaagaagtga ctatccattg tcactatcgc tttatcgggg aattgacacc
    25681 aacaatgaaa gaattgttgg aaacgattcg tcccatggct gaagtcacaa agcagctttc
    25741 tgagaaaaat gacgaattag aaagagaaaa tcatcatctt cttgaggaaa atacaagact
    25801 agaccatacg ttaaaaacaa ccacaaatcg ctattgcaca ttgttggaaa gtgatgaatg
    25861 gacaataaaa catagactag gacgacgtaa gaaagaaact tcgaaaaaaa tccaagaaaa
    25921 agaactttct atatgtattg acgagaaaat ctgggatgca gaaacaaaaa tattaaaaat
    25981 catcggatgg ggaatcgcta attcggatcg ccagcccttg tcctataagt tatcagctga
    26041 ccaatcgcca tttttcgaag caattcctgt ttcacgagaa gaagtcaatc aagcagaaca
    26101 gctcgcaaaa ggaacagaag cgggatttga gttacgaatc ctttgcgagc aagaacgttc
    26161 attcttagtg gaagcagtag ctcaaaatgg ccaatcatgg atcattgaaa tgtaaataat
    26221 gattaactta taaagataag gagtaaacga atcgtgcaaa aaaaagaaat tgccgtattt
    26281 atcgatcaaa tcactcgtga acgggccact ggcgatttgc ttattgtggg ctgggcaatt
    26341 gatgaagtga ccaaagaaat ccctacgata aaggtagaaa aagaaaatgt gattgctgaa
    26401 gcaacacatg tcgtaagatt ggatatcaat catttatata atcttgatgt taagacccaa
    26461 agcggtttta aggtacgttt atcagggaaa atgagaggaa aagccatctt agacttccaa
    26521 acagcgagac atcaaaatgg catagctgtg aaattaaacg gtaaataccc ttatgatgac
    26581 ggcattgaat cttcatggga aagaaaaaaa agattactga aaaaagggat aaattatgca
    26641 aggactcatg gcgtaaaaaa agcgatccgt cgggtcaaat tggaattgaa gccaggatcg
    26701 atcgactatg cagagtggat cagtcgtcat gagaaaccag atttgaaaga gcaaaggaaa
    26761 gaagcacaag gatttgcgta ccgtccattg atttccatac ttatgcctgt ctataacgtt
    26821 gaaatcaaat ggctcgaaaa atgcattgat tcggtactgg atcaaacgta tgatcattgg
    26881 gaactatgta tcagtgatga tgcttctact gatccagcta tccgaaagtg tctggaatcc
    26941 tatcaagcaa aagatgatag aatcaaagtc gttttccgaa aagaaaatgg acacatcagt
    27001 ctggcaacta attctgcatt ggaaatagca gaaggagaat ttatagcact cttagataat
    27061 gatgatgaat taccgccatt tgcattatat gaagtggcaa aagtgctaaa cgtacatcca
    27121 gaactggatg tgatctacag tgacgaagat aaaatcgatg cagatggcaa tcgctttgat
    27181 ccgcatttca aagcagactg gtcgcctgat acattgatgg gaaataatta tatctctcac
    27241 ttaggcgtat atcgaacaag cattgttaaa gaacttggcg gtttccgtaa aggctatgaa
    27301 ggttctcaag attatgattt ggtccttcgt gtgacagaac aaatccctgc agatcatatt
    27361 taccacattg accgagtctt gtatcattgg cggacgatcc caggatcaac tgcaagtaat
    27421 ggcgaagcca aaagttatat ctatgattcc ggagtgaaag cattgacaga tgccctgtct
    27481 agaagaaaca tcaaaggaag cgtacgtcct ggcagaattt ctggatttta tgagattgct
    27541 tatgacgtct tgcaagagga tttggtcagt gtgatcattc caacgaagaa tggctatgaa
    27601 gatctaaaaa cttgtgtgga ttcgatcatc gaaaaaacgt cttattcaaa ttatgaaatc
    27661 attattgcgg ataacggaag tacagatcca aaaatgcaag aattatttgc agaatacaag
    27721 catcagctga aagaccgctt tatcgtagaa ttgattgaca ttccattcaa ttattctcga
    27781 attaacaatt tagcagcaga aaaagcaaac ggcaaatact ttttattctt gaataacgat
    27841 acagaagtga ttgagccaga ttggatgacg gtgatggttt cttatgcaca gtttgatcga
    27901 atcggctgtg taggagcaaa actgttttat ccagatgata caacgcagca tgcaggagta
    27961 ttattaggaa tcggtggtgt tgcagggcat gcattgaata actatgatcg aacacattgt
    28021 ggttatttcg gccgattggt cattgacgtc aattacttag cagtcactgc agcttgtatg
    28081 atggtcaagg cagctgactt caatgctgtt aacgggtttg atgaaacatt agaagtagca
    28141 ttcaacgatg ttgacttgtg cttgaaagtt tatgaactgg gtcgttacaa tgtctatgca
    28201 catcaagcag aattgtacca tttcgaatct aaatcaagag gttatgaaga tactccagaa
    28261 aaacaaagac gttttgctgg tgaaatcaaa aaaatgcaag ataaatggcc agcatatatt
    28321 gcgcatgatc cattttacaa tgataattta acaaaagaag gaatcggcga cttttcgttg
    28381 agaccagatt aaactataat aaaaagctgt tatgttgtga ttcgctcgca cataacggct
    28441 ttttatagtt ttttgtcaaa aaaaggcaga aggtgccgac tcaaaaaaat aagtcgaggt
    28501 tgggacagaa gtgtttaact ccgagaaata agaagaaatt cacgaaaatt gcttttcaaa
    28561 tttttgtgaa tttcggctta tttaagaaga agttgcttct gctcccaccg tttattcgtt
    28621 tttaaagaat gagacaaaag tgtttcttac ttttgtccca cgctcttatt catgctcaga
    28681 gcgccaatag atacaaaatc atagccaaag tttcacgaac cctagctgtc aaagaatcga
    28741 tattttattt taatataggc tattttaaaa taaatggttt aaggtattcc tctacaaaag
    28801 ccactctatc aattatcatg ggtttaaaat aagaagtgat ggagataacc agattgttct
    28861 tagcgtcaat ataaagaaca tttccactat taccaattgc tgaatatatt tcgttctcag
    28921 aatctaatac ccaccataaa tagccatatc tcatattttg taagtcttct aaagcactgg
    28981 ttctaggttt gaacatctcg tttatccaca tgggtggtac gatttgtttt cctttataca
    29041 tccctttatt taggcataat acaccaattt ttgccagatc acttgccgat aaacacaaac
    29101 catatcctgc cgtcccgata tttagtggat cacaaaacca gacattggtt ttaggagact
    29161 tatccattgt aaactgctta tgttcttcag ctgtttcagc ataataattg acatggtttg
    29221 gtatccctat aggatcaaat agatacttat tggcaaaatc aacagttgtt agcttacttg
    29281 tctgatacaa caagccagtt aatatgtgta aacagacagt ttgatagttg aattcgccgg
    29341 ttataccttt tcttcctccc aataaatcta gtgatgtttt tgtccaatct tcacttgaac
    29401 agacttttgt ccatggatcg cctttacatt tgtagggtgc tttcattgtt agcaagtgct
    29461 tgattgtaat agcgtaaata gttttctccc cgcgtttcac tttatactct ggaaaataat
    29521 ctaatacttt atcatcgata cttttgatta atccttgctc taaagcaatg ccaatcagca
    29581 aagatacaat acttttcgtt gctgacatga tatgacaagt atcgtctttt ttataaccat
    29641 tccattcatc tgtataaact tctaccccat ccttatatgc gacaatttga catatatttg
    29701 gttgtcgaaa accaataaaa tcatgcaact cttgtttatt cataagatat tacctcactt
    29761 tcttctataa gcataatgtc attaaaaatc gatttcaatt ttttcgattc ttcacgtaat
    29821 acaggtattc ttatggacta gacagcgctt tgggaagatg gattctctga aaaatataaa
    29881 ggttcacttt atgagtggat aaaaaaagca gcaaatactt cgacttcttt aatttaccaa
    29941 cattagtgaa aatcgattca tctggagatt tgtaatttag agtccttgtc ttgattagag
    30001 gtgtataaag ctttttatta gacattttta aattccatta caatttgctt ataaactagg
    30061 tttttaaagg tgactatggt aagataatag agatattatt ttgtgattag gagtgtatat
    30121 atgaataaaa atggagaatg gagtgctgca cgacggatat tcattatatt aatggatgtt
    30181 attgtataca atgcagcaat atatagtagt ttcttactga agtttcgtgg agagatccca
    30241 ttacgaaatt tagaaacttt ccaacactca gcaattatta tttcagtgat ttttattgcg
    30301 ttgaacattt tgttgggtgc atatgttttt tataatcgaa tgatcagtga catcgtgttt
    30361 gtcacagtca tcggtcaggt attgatgaca ctagggatca tggtagtgac ttttgcgggc
    30421 cgctggtttg cttttccacg tcttgttatc ttactttcat ttgttctcgg tacgcttttc
    30481 ttaagtatct atcgtattct cgtatataaa ctttatttac gcgtaagtcg agataaaaag
    30541 gtcgtcatta ttgggttaga aaaggatgtc gcaccagcaa tccaaaattt tggttcaaag
    30601 aaaaacaaca aacataaagt cgaagcagtc attcttgata actattatgc aaacatcaaa
    30661 aatatgatta aagacatcga tattgtctat cttgcttctc atatcgaaga aactgaaaaa
    30721 atcaaaatct atcaattagt tactaaaaat gaaaaaaaat tgtttttgaa tacaacattt
    30781 gaaaacttga cattgatcaa tccaaatatt atgaatttcg aagatgaaag tattattgaa
    30841 gcatctggat ttagaatcca acctgaatat gaactattca aacgtttgtt tgatatcatc
    30901 gtttcacttg ttttattagt tattgcttca ccatttatgt tattcacagc aattttagtc
    30961 aaagtgacat caccgggacc aatcatctat aaacaagtgc ggatcacaaa aaatcaaaag
    31021 gaattttcaa tctataaatt ccgctcgatg accgccacag ccgaagcaaa atctggacca
    31081 gttttagcta agagcaatga tgcacgagta acgcctgtag gtaaatttat tcgagctgtc
    31141 cgctttgatg aattaccaca aatcttcaat gtgctgaaag gcgatatgtc gatcgtagga
    31201 ccacgtcctg aacgtccttt cttcgtcgat cagttcaatg cagaaaaccc ttattactac
    31261 ttacggcata atgttcgtgc tggtatcact gggtatgcac aagtctatgg aaaatatgtc
    31321 tctgattaca acagtaaatt acgttttgat ttactttata tcaaaaaata ttcattgatg
    31381 cttgatttaa agatcttgct gcaaaccatc aagatcctat ttgataaaat gtcctctcaa
    31441 ggacttgaag aagacgaaaa tgtgatctca ttggcagaaa ttgcttttcc gaatgaaaaa
    31501 atctttcgct agttgggagg cgtaaaaatg aacaatccga aattcagcat aatcgtacca
    31561 gtatacaatg cagaagcaac tattggtcga acgattgata ttctaaaaga attggattat
    31621 gaagagtacg aagtcgtttt agtaaatgat ggatcaacag atcaaacaca ggaaatcatt
    31681 caagaactga ttgaaaatga tgaacgtttt gaattgatta ctacgaccaa tcaagggccc
    31741 ggattagcaa gaaacgaagg aataagacag tcaaaaggag aatatctctt attcttcgat
    31801 gcagatgaca cgccagtaaa aacgatcttg tcagattatg atcatttgct agaaaagagt
    31861 ccaaaagcgg atcttgttgt tagttcgttt gtttttcgta caatggacga gggaagaatc
    31921 gtttccgaaa aagaaaactt agttacagaa tgtcactatc taactcacga agagtttata
    31981 aaagacatgt atcagttaat gaatgaacag ttgatgtatg ttgtatggaa caaatgctat
    32041 cgtagcgata ttctgaaaaa taaccaaatt ctatttaaaa cttataatag ttgtgaggat
    32101 cgaatattta acttacatta ttatgaatac tgtcatcaag tgatcatgaa cccaaaagta
    32161 gaatatattt atgaatttga aggtgggaag gggatcacta atcaataccg acctaacaag
    32221 ttcgaaacat ttaaagaatt ctattcatta gcaaatactg taacagacga tattaataaa
    32281 gacggtatgg cggcgcttct tttaaaaggg acaacttcag ttattttttc tatttatagt
    32341 acctctgcaa gaacttcaaa agagaagaaa gacgaagcaa agcagatatt gagtgatcca
    32401 gtgatccgag aagccaagca aattgctaag acggattctt cagcaaaaaa aataacaaag
    32461 ttgctttaca atatgccagc tccactattt ttatctgctg taaaagttgg aagcttcgtt
    32521 gaagtgaaaa tgccagggtt aatggctgct ttgaagcgag tatattagtt aatggaggaa
    32581 aatataatga aaagaatttt gcattttcag ggacgaatgg gtttaggtgg agcagagtct
    32641 ttcatgatga atttatatcg taaaattgat cgtacaaact atcaatttga ttttttgatt
    32701 tatgaagatt atgcagatgt tcaagactat cattcagaga ttgaaagatt aggaggccgt
    32761 atttttgttg tacctaatcc taagaaaaat atttttaaat atttaataga agtgaataag
    32821 ttactaaaaa aagaatcttt ttctatagtt cacaatcagg tttattttgg cgggggaatt
    32881 aatttatggt tagccaaaaa gaatggaatc agacagagaa ttgctcatag ccatgcaact
    32941 gaagatggaa aatctcaaaa tattgtaatg aatgtattgc gtaaattttt aaccaaattg
    33001 ttgttacaaa atgcaacaga ctaccttgcc gttagtcaag aagctggtga aagtctgttt
    33061 caaaaccacc cctttgagat agttcataat ggtattgatt tagagcttta tagtaaaaat
    33121 tcagaagcta aggttaataa gagaaaagaa ttggatatct caatgagtac ttttgttgtg
    33181 ggaaacattg gacgattaga gaaacaaaaa aatcaatctt atttgttaga gattttttta
    33241 gaaatactaa aaatgaattc tgattcttac ttgattttag taggtgaagg gtcacttaga
    33301 aataaactga aagccaaagc agtagaattg gatatagaga aaagagtaaa atttttagga
    33361 gaaagaaacg atattcccga gttattatct gtgatggatg tttttgtaat gccttctctt
    33421 tatgaaggtc tgccaatggt tggattagaa gcacaagcag caaaattaaa attagtctta
    33481 gcagatacta tttccaaaga tacaaagtta acaaataatg tggattttgt atcattagat
    33541 gaaacaccac aagaatgggc aaaaaaagta ataaaagagc cgtatgctaa taaaataaca
    33601 caagaactaa agagttatga tgtttcgtac actactgaac aaatggagag tatatatagt
    33661 agagatcatt aaaaatgttc aagatatttt aggagtgatt atttttgaaa atatgttatt
    33721 tgatattggc atacaatgat attggcaact taaagagatt ggtcaatcga ttgaacgaaa
    33781 atgcagtttt tattattcat atagataaaa aaactgatat agaaccattt attgaagcat
    33841 ttaaatcata tgataatgtt gaatttttat gtaataaaaa ccgtgttaaa atttattggg
    33901 gtggtttttc cattgtacaa gcagaaatca atttagtaaa gagagcatta caaaatgaga
    33961 aatatttaaa atatgtatta ttatctggtg ctgattatcc aatcaaagat aatgagtata
    34021 tttataatta ttttaaaaag aatagttcag tggagtttat tcgtggaata gatctagatc
    34081 aaattaaaca taaagaattt tattataaac atatagatgt atatcaaaaa catgattatc
    34141 ctagaattaa taggaataac acaactgcat ttaaaatttt tagagctata attaatcgtt
    34201 gtctgaggat gattaaactt cccccaaaaa ttagacacca taaatttgat ttgtatcatg
    34261 gttctcaatg gtgggctttg tcgaaagaat gcctaacaga attaatacaa atgtatgaac
    34321 aaaatcaaca agactacctg aattttaaaa taggtatgtt tgccccagat gaaaaatttt
    34381 ttcatacact tttttttaat tcctcgttca aaaataaaaa tgttattgga ggaccagatt
    34441 taccacttga attgaaaaat attgaagaaa ctactttaca aacttcgaaa ttagcaaata
    34501 ttcatattat tgatccttcc atgaacaaat ggtttgatga aagggatata gatcaaataa
    34561 aagaaagtga aaaattattt gtaagaaaag ttaaatcgga ttactctgat aaactattaa
    34621 atagaattga taaagaaatt ttgaaagttg gaaatataga tgaatagaat agtacctgtt
    34681 ttagagaaga gtttattaag tcgagatgcg tttcgagtaa taaatttaat catttgtctg
    34741 ctttatttta tgcctagtac ttttaatgta actaatatcc cgatgaaaat agcttttgct
    34801 tggggtggaa ttatagtttt gtatgaggtt tttataaaga aaaatttttt taaaatgcgt
    34861 ttttcttggc tactgattgg agcaatgatt agttttatct taactataat cattaacaga
    34921 gaaaattttt taattccatc tatttataat tttggatatt tgctgattac tttgatagta
    34981 atttttcctg cagacttttc acaaagtgaa gaggaaaaaa agaaaaaaat ggtgtatttt
    35041 aataatgttt tcattatcat aattttttta gctgcgctaa tatctatcta tcaatttatt
    35101 tttttgattt cttatcatgt cccaacagga acgccaggat tacttgcaag acaaggtttt
    35161 attgaacatc ggttatttgg tgtctataca agtccaaatg ttggagctat gtttggatat
    35221 acttctatta ttttaagttt aattagtgta ttaatttcaa aaataacaaa aacgattcgt
    35281 gttttttata tgatgaattt tatcgtacaa atattttata ttacactttc ttcgtctaga
    35341 ggtgcccagg tagtaatttg ttctttttta gtattatttc ttttgttgtt tgccaattca
    35401 aaatttagaa agagcattag agaagtacta cctgtaaaaa tcaaatggat ggtaagcata
    35461 ttattagttc tattggtata tttttctttt ggtactaatt atgctaagga ttttttagca
    35521 acaattcctg tatcgattga tagaaaagta gaagttatag agtcaaatga atcagataaa
    35581 actccacttc cagaaaaaga agtaatatta cagcattcta gtgataactc cgaaatttca
    35641 gctggtcgtt ttacgatttg gaaagctgcg cttaaagtta taagaccaac tttgttattt
    35701 ggttatggag agaccgattt ctatgggaat agcgatgcaa aatttttgaa aaaagtagat
    35761 cttgatacta cagatgtgaa tgaactaaaa agagcacatg gaaacatgca taatggattt
    35821 cttcaagtac ttgtatcaag tggtataatt gcttttatat gtatctatgc tttctatgtg
    35881 ttaaatatct ttagtttact caaaacattt tttagaagta aagtgaatta tgcgtttctt
    35941 ggtattgttt taatttttat actatctatt tttatagatg aaatggtgga ggctcatgta
    36001 cttttcaata agcgcgatgt catttcaatt gttttctggt attatttggg aagcatttct
    36061 tacttgtatt taaaaaagga gaattaatat gaagacagct ttcattgctt ggactccttt
    36121 acatttgatt aatatattaa atgtttatca aaatttttac cgagaatcaa aaggagattt
    36181 atttatttat tctgaatttg aaaacgctag aagatatagt gagcgtataa aagaattagg
    36241 gctatttaat gatgttgttt ttgtgaatca ccggaaaatc ggttcttcct ttaaacgtaa
    36301 aattaacttg ttaactaacc ataatcaatt tttctcggat gatttatccg tttatgatga
    36361 aatttttata cagggggaaa attatttcac aaaaatactt ttctccaatg tttacaaaaa
    36421 aaatccagat gtaaaactaa attatataga agatggtttg ggtacttatt tgaagaagag
    36481 tatattttca acaagtaaaa acgttcaaag agtttttaaa atattaaata aaaatagcat
    36541 cttcaaaaaa aaaattgacg attattttgt ctattgtccg gaattgttac tttatgatgt
    36601 aaaaaatata aaaaaaattc ccaaaataga tgaaaacagt aaattgatga aaaacataca
    36661 atcaatcttt gggatagaag aagtttttgt cggagataaa tgtatctttt ttgatcaacc
    36721 tttattatct gatggttatg gcatagatga aacagatatt ttcgctaaag taaatagtat
    36781 attttctgga aaaaaagaaa ctttaattaa gcttcatcct agagcaagga caaatcgtta
    36841 tggtgaaaaa aacatattga attccagttt accgtttgaa gtcttgctac ttgaaaatga
    36901 cttctcttca acacttttga ttagtcctat atctacaatt tctttttcac catctatgat
    36961 gtttgaaaag acgatcaact ctattatgtt ggctaaatta attttaaatg aatatacagc
    37021 attatctgaa gataaaaaag aaacattgac aaatattgtt cttttctgtg aacattataa
    37081 ccgtctatca gaagaaaaaa ttttactccc agaaaactgg gcagaattaa gaaagttggt
    37141 agagtatggg attatttaac acactttcca agtcaaaatt agttaagtcc agtttctggt
    37201 atactatagg gaattttttt attaagggaa tttcattcat aactattcct atttttgtaa
    37261 atattactac tcaagcagaa tatggtttga ttaataattt cacttcattt gtatcaattt
    37321 tttcgattct tgttgggcta agcctaaatt cggcaattaa taatgcaagt tttgactata
    37381 aagatgacat aaatgaattt atgtcatcgg tactttctct agctacactt tcgttaattg
    37441 tgttcttatt aatagggaac atatattttt tgttttcaaa tgcttttttt gatatgaacc
    37501 aacttgtatt taatttgatg ttattacaaa gttttgctag ttttgtaatt agttatatcc
    37561 agtcttattt tacgattaac tttaaccatt ttaaatattt gattttatct tttatatcta
    37621 cttttttgaa tattgcaatc tctgtagctt tgatgcagac attatatttt gatgataaat
    37681 atgttggcag agtagtcggc ggaacactgt catttgtgtt gataggttta gtaatttatt
    37741 taagaataat gataaagggt gctcattttt ttgataaaaa acagtggaga tacgctttaa
    37801 aaatctcttt gccgctaatc ccacattcct tagcaaatat agttttagca caattcgata
    37861 gaattatgat taattcttat ttaggtcctg ctgcgggggg aatatattcc tacattagta
    37921 acataggtat tattctaagc gtaatatgga tgtctactaa taacgcctgg gttccatggt
    37981 tctatggtga gatgagtaaa aataatgaaa aaaaagtgaa gaaagttagt aactattatt
    38041 tagtagtctt tactttgatt acgatgattg taatggtagt ttcgattgat ttagcaaaat
    38101 ttatggctcc gaaagactat tattctgggt tatctttagt ggttccgata accttaggct
    38161 atttctttca gtttttatat agtttaccag ttaatgctga attttatgag aaaaaaacat
    38221 cgtttattgc gattggtaca gtagcaagtg ctatagttaa tatactatta aacatgattt
    38281 tcatacctag gttaggaata attgctgctg gatacacaac cgtatttacg tattttttac
    38341 tttttatttt tcattataat atcgctaaaa aaattacgaa taaacaatta tttgacacaa
    38401 aaaaaatatg tatcataata atttttgtat caattttttc tttgatactt catattttaa
    38461 tcaatcaaat gttgattcgt tacgttttga catcattatt gataattagt ttagttatat
    38521 attttttaaa gattaagaat cgaattatag atgactataa ttcataggag gagatataag
    38581 tgtttaaagg aaaaacaata ttagtaactg gcggaactgg ttccattgga agtgaaattg
    38641 ttcgtcagct tttaaaatat gaaccaaaag ctatcagaat ttatagtaga ggtgaagaaa
    38701 aacaatttta tatgcaacaa gagctctcaa atcacactaa tttgagattt ttaattggtg
    38761 atatcagaga ctctcaaagg attgattatg catgtcgtga tgtggatatt atttttcatg
    38821 ctgccgcaat gaaacacgtt ccagcaagtg aatataatcc tatggaagct gtaaaaacaa
    38881 atgtgatggg aactcaaaat gtaatagatg cagcgatcaa aaataatgta aaacattttg
    38941 taggtatcag tacagataaa gtagtgagtc ctactaacac catgggtgcg acaaagttat
    39001 tgagtgaaaa attaataata gctgccaatc agtataaagg aaaaacagaa acaatatttt
    39061 cttgtgtaag gtttggaaat gtcatggggt caagtggatc tgttattcct ctttttagta
    39121 aacaaataaa aaacaataaa gatattactt tgacagatgt tgatatgaca cgatttatga
    39181 tgtcaatacc ggatgctgca agattagttc tgtctgctgc tatgaattca aaatttggag
    39241 aaacatatgt cttaaaaatg ccggcaatca atattttaac tttagctcaa tcattaataa
    39301 aaatatataa tgatacacat gatgaaaaat atagaggtga aataaaagtt gtaggtatca
    39361 ggccaggaga aaaattatat gaagagctaa tgactacaga cgaaattgaa cgctcatatg
    39421 aaaatgataa aatgtatatc attccaccac actatcatgc tactgacgaa ctgtacaaag
    39481 attatgaaaa aattaaaatc actgcatact cttcagatgc aacagaatta atgagtggac
    39541 aggaatttat tagaatcgca aaagagaata atgtcgtgac ttggtaagga gttttatgat
    39601 gaaatcagaa gtatatgtaa ttgcagaaat tggtgtaaac cataatggaa gtctagattt
    39661 agctttagaa agtattgata aagctaaaga atgtggagct aacgcggtta aatttcaaac
    39721 atttaaaacg aataagctag tttccaaaaa ggctccaatg gcaaaatatc agaaggataa
    39781 tcttaaagag gacagttctc aatttgaaat gctaaaaaaa ttagaattat ctcaatctga
    39841 ttttattaga ataaaagatt attgtataca aaataaaatt gattttttgt ctactccttt
    39901 tgatgaagaa agtgcagact ttctaaaaca aattggtgta caaggattta aaattggctc
    39961 aggagattta acaaatttac cttttcttag aaaaatagat atgtatgggt tgccagtttt
    40021 attatctaca ggtatggctg atattcatga ggtcagtgag gctgtagatt gtttcataga
    40081 tagtccagtt actattttac attgtacttc aaattatccg gctagttctg aagatattaa
    40141 tttattggcg attaacacat taaaagaaat gttcgggata cccgttgggt actccgatca
    40201 ttcattggga tatgatgttg gtatttgtgc tgttgcgatg ggtgctaagg taattgagaa
    40261 acattttacc ttggataagg aactacctgg tccagatcat aaagcttctt tagatcctca
    40321 ggaatttgca gattttgtaa agcatattag aaacactgaa atatttttag gtgatggtgt
    40381 taagcgagca atgccttctg aacttagtac aaaagaagta tcaagaaaaa gcctagtggt
    40441 cactgagaat ttaaatgtgg gagatattct tacagagaaa tctcttacaa taaaacgtcc
    40501 tggaaatgga atagctccta agtttttata tcaatatatt ggcaaaaaag ttaaaagacc
    40561 aataagtgca gatagtgttc tgcttgagga agatgttgaa tgaaaaaaat acttatagta
    40621 agtggaacac gagctgatta tggaatatat aaacctgttg ctgagaattt actacaagat
    40681 aattgggatg tatcatttgt tgtttctgga atgcatttat cccataaata tggatttact
    40741 aaagaattga tcttagctga cggatttaga attagtggag aagttcaaag tttgttttta
    40801 gagaacaata agggaaacat ggctcggtct gtggcattag agataaatgg tttcacaaat
    40861 atatttgaac aaactagccc tgattttgta ttattactag gggatagagg agaaatgttg
    40921 gcagctgcga tagcttgttt gtatcttgga atcaaaacag cacatattca cggaggcgaa
    40981 gtgtctggta ctgtagatga atcaataaga catgccataa cgaaaatagc atctgttcat
    41041 tttgctgcta cggaaaaaag caaagagcgt ttaataaaaa tgggggaaga ttcttggaga
    41101 gtttttcccg tcggagctcc tagaatagat actattttaa ataatagatt acctagtttt
    41161 agagatataa aagaaaaata tcatctaaaa tttgaaaaga aaaaatacgt tttgcaagta
    41221 tttcatccag ttgtaaccga actagaaaat atagaaaaac aaattttagc tttgatcaat
    41281 tcaatggaac aacaatctca accaattatt tgcattttac ctaatagtga tgctggtagc
    41341 gaaattatca gaaaaatgta ccagaaatat ttaaaaacgg atattattta tattacgaat
    41401 ttagagccgg aggaatacct gactatatta aaagagtgca aatttatgat cggaaattct
    41461 tcttctggga taattgaagc tgcatcattc aaaataccag taataaattt aggaaccaga
    41521 caaaatggac gagaacaatc taaaaatatt ataaatgcaa atctaaatga aaatgaaatt
    41581 gaaactgctt tgaataaaat acaagatcct cagtttataa aaagcttgaa aaatgttaag
    41641 aacatctacg gtgacggcaa cagttctaga agaataacaa aaacattgaa tcaaatattg
    41701 aatgatgggg aagatattaa gtggattcaa aaacaaatag cttattaaaa tatactagtg
    41761 atccatacat tattattggg gctggcggac acgcaaaagt cattattgaa accttaagat
    41821 tagaaaataa gttaatatat ggattttttg atgataagca aaataaaatg caagatctga
    41881 aatatcttgg gaaaataaac gaattgaata gctgggcgga tagcaaaaaa aaaatctata
    41941 aatttattgt agctattggt gactgtgtag taagaaaaaa gattataaaa aaattgaata
    42001 tgccaagtga gcaatatgga atagctgttc atccaagtgc tatagtggca aaagaaattt
    42061 caattggtta tggaactgtt atttttgcga atgctgtaat taacccagat gctgtaattg
    42121 gagagcatgc tataataaac acaggtagca ttgttgagca tgattgtaga attaataact
    42181 atgttcattt atctccaggt gtatgcttag cgggtggagt acatgtaggt gtaggaactc
    42241 aaataggaat tggttctcaa tgtatccaga tgaagaaaat tggatcttgg tgtatgatag
    42301 gcgcagggag cactattgtt aaggatattc cctcacattc cttagcttat ggcaatccag
    42361 ctaaaattaa gaaagaagga attaattttg aattctagaa ttttattatc aagtcctcat
    42421 atgggaggaa cagaagaaaa atatgttgct aaggctttta aagataattg gatagcgcca
    42481 ttaggtgaaa atgtggataa atttgaagaa agtattacaa aatatactgg ttctaagggc
    42541 ggagcttctg cgttaagttc aggtacagct gccatacatc ttgccttaag actgcttaat
    42601 gttggaaaaa acgatattgt ctttgctcct tcatttactt ttatagctac agtaaatcct
    42661 attttatatc aaggggctgt accagtgttc attgactcag aacctaatac atggaatatg
    42721 agccctgttg cactagagag cgcattagaa gaagctgaaa gaaacaacca attacctaag
    42781 gcaatcatcg tagtgaattt atatggtcaa atggctgatt atgaacgaat tttagctatt
    42841 gcaaaccaat ttaatgttcc agtgatagaa gatgcagcgg aatcgttagg ttctacttat
    42901 aagggaattt cgtcaggctt atttgggaca attgggatct attcatttaa cggtaataag
    42961 atcatcacaa cctcaggtgg aggagctcta gtgtctagtg ataaaaaata tgttgagcat
    43021 tcaagatttt tagcaacaca agcaagagat caagcaccgt attatcaaca tagcgaaata
    43081 ggttataatt accgtctaag caatatttct gccggtatcg gacgtggaca aatggaagta
    43141 ttgaatgata gagtagctaa acgaagagaa attttcaatc gatataagga agctttttct
    43201 ggaattgata gaattgaaat gatgccagaa gtggatggca tggtgccaaa tcgttggttg
    43261 tctactttaa cgatcaatga ttataattct attgatcaag tagttaacgt aataaataaa
    43321 ctaaatgaaa aaaacattga aacaagagct ttgtggaaac cactacattt gcaaccagta
    43381 tttcaagggg taaaaatgta ttaccatgat aataatctta gtgtgtcaga aaagttattt
    43441 aatagcggct tatgcttacc ttctggaagt aatatgacag atagtgaaca agaatttgtt
    43501 attgatgagt ttaaaaaaat attcaagtag gtgtgatatt ttatgaacat aggaattatt
    43561 ggtttaggtt ccatggggaa aagaagactt agactcattc aagaacactt taatgatatt
    43621 ttactatgtg gtgttgatac taatgaggcg agacgaaagg aagttgaaaa ggaatttgga
    43681 ataccaactt ataatagtct aacagaggca aaaaatttgt ttgaaataaa ttcagttttt
    43741 gtttgtacat cccctataac ccatgaattt attataaaag aggctttaaa tttagattgt
    43801 aatatcttta cggaaatcaa tttattaaat gaatattatg atgaaataat cgaagtagct
    43861 aaaaagaaag atagattact ttatctatct tctacatttt tgaagagaaa agaaattcaa
    43921 tatattaagt ctaaagtgac gcataataaa aaaatttctt atcaatacca tgtaggacag
    43981 tatttacccg actggcatcc ttgggaagat tatcgcaatt tttttgtttc aaacaaaaaa
    44041 actaatgggt gtagagaaat attcgctatt gaattacctt ggattataga tacatttggg
    44101 aaagttaaat cgtttactgt aatgacccag aaattatcca atcttgatat tgattattcg
    44161 gacagtttca ctcttattat tgagcatgaa actggtatag ttggaacttt aagtgtagat
    44221 gttgtttcaa gagtagctaa aagaaattta actataattg gtgaaaagat tttaatagaa
    44281 tgggaaggta acccggattc tctattttca tggaatgaag aaacttctag tatgacagat
    44341 attcaattgt acgatgaggt tatgcatgat aataattatt cacatactat tattgaagat
    44401 gcatatttag aggagattaa agaatttttc acgcttttgg aaaagaaaat ggaaccccaa
    44461 tatacttttg aaaaagataa gtatattatt aacttaatta acgacattga ggtaaattaa
    44521 tgatgaaagt aatttttttt gggttagggt caattggaaa gagacatcta aaaaatctaa
    44581 taagctatgg aaaaaagaat tctattaatt ttgatataac agcttatagt agcagtggaa
    44641 aaaaagagtt tgaagaaata acgtatattc aaaatagaga cgatttggat acacattatg
    44701 atatagcttt tattacaaat ccgactttta agcatctgga aacactaaat gtaattgttg
    44761 aaaaagttga ttacatattt ttagaaaaac ctgctttttc tgagagtatt gatcttactc
    44821 aatataatta tgattacaaa aatatttatg ttgctgctcc actgaggtat aaaaatatca
    44881 tggaagttgt tcgtaatagt attcaaagta aaaaagtata ttctgtaaga gctatttgtt
    44941 ctacttatct tcctgattgg agaaaaggta ctgattatag aaataattat tctgccttta
    45001 aatctatggg gggaggagta gaattagact gtatacatga attggattat attataaacc
    45061 tatttggttt ccctaaatca gtaaaaaaac agtttggtaa atattcgaat cttgaaatta
    45121 acagtaatga tttagcaaca tatatattga gatacgatga taaaattata gaaattcatt
    45181 tagattattt tggaagagtt cctacaagaa aatttcaatt gtttacttta gatgaatgta
    45241 tcaatgttga cttattaaat aataaaataa gttttgaaga aaacattgtt aaagaaatgc
    45301 ctgaatctgc taatgatatg tatgagaagg agttgaaata tttctttgaa aacgtagtaa
    45361 caggcaaaga aaactggaat gatttatatc atgcaaacga agtattgaaa atagctgagg
    45421 agaaataaat ggaaatttta tttactattt gtggtagagc tgggtctaag gggtttaaaa
    45481 ataaaaattt gaaatatttg gcaggaaagc ccctagtcca tttcgcttta gcaatgatag
    45541 atatctatca acaaaaacat cctgaacata attgcacgac ttgtttgaat acggacagta
    45601 atgagttagt agaattgacg actaagttaa atccgtctgt gaaaattgta gaacgtaaac
    45661 ctgaattagc tacagatact gtagggaaaa ttgaagtgat acgtgattca ttcttacaac
    45721 tagaaagaga agataatata tttgatttaa ttatagattt agatttgact tcacctttac
    45781 gtgaagtttc taatcttgaa gaattaatag atgaacatct aaaaaattta gataaagacg
    45841 tctacttttc agttgtttct gcaagacgta atccctattt taatatggta aaaagaattg
    45901 aaaatgaagt tactatagtt aataaatcaa gatacacatc taggcaacag acacctgaag
    45961 tttttgaaat gaatgcctca atgtattctt ttaaacctga atttctaaaa aaaagtaatt
    46021 atatttttga tgggcaatgt gggataataa aaatgagaga ttatctaatt ttagatattg
    46081 atagtgaaga agattttaaa tggttagaat ttttgtttcc taaattttta gaagattctt
    46141 cggagcttca agatatctat aattatttat atcggaggta aaaggatgag ctgttatctt
    46201 atcaccggtg gggctggctt cattggttct accttagcca atcatttagg agaagaacat
    46261 gtggtaatcg tcgtcgatga cttatcaatg ggaaaagtag aaaatcttga tatgacgaaa
    46321 aatatcactt ttattgaggg agatgtcgct gagaaatcct tgatggaaga gatcatgaaa
    46381 gctaataaat ttgattatat ctttcattta gcagcagttg ctagtgtggc agattcagtt
    46441 gcccgaccag tagaaacaca tcgtgtgaat tttgaaagtg tattaatgat tttagaattg
    46501 atccgcaagt atcaacctga tttaaaacgg atcgtgttta gttcttcagc ggctgtttat
    46561 ggggatgaac cgactttacc aaaaaaagaa gagtccgtga ttcgcccatt gacgccttat
    46621 gcggttgata aattcgctgc agaacaatat gtgctagatt attgtcattt atatgatgta
    46681 cccggtagcg cagttcgttt tttcaatgtc tatggtccaa atcaaaatcc gaattctcca
    46741 tacagtggtg tgatttctat tctcgtagat cgctataaga aacaaatcgt aggagaagca
    46801 acttcattta cattatttgg tgatggaagc cagtctagag actttgttta tatagatgat
    46861 gtaatccaag cattactttt agttgcgaat gaggaagctg cactggggaa acaattcaat
    46921 gttggaacgg gtaaagcaac cacacttttg gaattgattc atgcaatcaa tgaaattctc
    46981 ggtgtagaat tgacacttga atacaaagaa gagcgttcgg gtgatatcca tgactctcta
    47041 gcagatatta ctaagatcca gtcaattggc tatcaaccga aatatggtat tttaagtgga
    47101 atgactaatt atttgaaaac tgaaatcaat taaaacatac taagataaga ttagagggta
    47161 aattcaggct ctttgtcaat aaggactgat gagttttgta aaatcaaatc tgggatagaa
//
LOCUS       DAYYEF010000016        45893 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000016 DAYYEF010000000
VERSION     DAYYEF010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45893
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.016"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..733
                     /locus_tag="ACHA1B_001068"
     CDS             <1..733
                     /locus_tag="ACHA1B_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFM8701847.1"
                     /translation="LSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLN
                     VALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYS
                     YGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYIN
                     KGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKL
                     LGSIQTNLPESVLLDCGMDFLKDIC"
     gene            791..2830
                     /locus_tag="ACHA1B_001069"
     CDS             791..2830
                     /locus_tag="ACHA1B_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HFM8701848.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2939..4090)
                     /locus_tag="ACHA1B_001070"
     CDS             complement(2939..4090)
                     /locus_tag="ACHA1B_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HFM8701849.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4244..4774)
                     /locus_tag="ACHA1B_001071"
     CDS             complement(4244..4774)
                     /locus_tag="ACHA1B_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HFM8701850.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4873..5223)
                     /locus_tag="ACHA1B_001072"
     CDS             complement(4873..5223)
                     /locus_tag="ACHA1B_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HFM8701851.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5380..6909)
                     /gene="ahpF"
                     /locus_tag="ACHA1B_001073"
     CDS             complement(5380..6909)
                     /gene="ahpF"
                     /locus_tag="ACHA1B_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008785 - alkyl hydroperoxide reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0000302 - response to reactive oxygen
                     species [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HFM8701852.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6919..7482)
                     /gene="ahpC"
                     /locus_tag="ACHA1B_001074"
     CDS             complement(6919..7482)
                     /gene="ahpC"
                     /locus_tag="ACHA1B_001074"
                     /EC_number="1.11.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HFM8701853.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7626..8288)
                     /locus_tag="ACHA1B_001075"
     CDS             complement(7626..8288)
                     /locus_tag="ACHA1B_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM8701854.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8472..10118
                     /locus_tag="ACHA1B_001076"
     CDS             8472..10118
                     /locus_tag="ACHA1B_001076"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFM8701855.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10109..11191
                     /gene="uxuA"
                     /locus_tag="ACHA1B_001077"
     CDS             10109..11191
                     /gene="uxuA"
                     /locus_tag="ACHA1B_001077"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFM8701856.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11299..12852)
                     /locus_tag="ACHA1B_001078"
     CDS             complement(11299..12852)
                     /locus_tag="ACHA1B_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8701857.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            13000..14289
                     /locus_tag="ACHA1B_001079"
     CDS             13000..14289
                     /locus_tag="ACHA1B_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFM8701858.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEAAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(14415..15494)
                     /locus_tag="ACHA1B_001080"
     CDS             complement(14415..15494)
                     /locus_tag="ACHA1B_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFM8701859.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(15603..16043)
                     /locus_tag="ACHA1B_001081"
     CDS             complement(15603..16043)
                     /locus_tag="ACHA1B_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFM8701860.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(16100..16510)
                     /locus_tag="ACHA1B_001082"
     CDS             complement(16100..16510)
                     /locus_tag="ACHA1B_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HFM8701861.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(16691..17125)
                     /locus_tag="ACHA1B_001083"
     CDS             complement(16691..17125)
                     /locus_tag="ACHA1B_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM8701862.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(17225..18073)
                     /locus_tag="ACHA1B_001084"
     CDS             complement(17225..18073)
                     /locus_tag="ACHA1B_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HFM8701863.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            18462..20228
                     /locus_tag="ACHA1B_001085"
     CDS             18462..20228
                     /locus_tag="ACHA1B_001085"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HFM8701864.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            20330..21589
                     /locus_tag="ACHA1B_001086"
     CDS             20330..21589
                     /locus_tag="ACHA1B_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFM8701865.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            21736..23037
                     /locus_tag="ACHA1B_001087"
     CDS             21736..23037
                     /locus_tag="ACHA1B_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8701866.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            23040..23891
                     /locus_tag="ACHA1B_001088"
     CDS             23040..23891
                     /locus_tag="ACHA1B_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HFM8701867.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            23904..24719
                     /locus_tag="ACHA1B_001089"
     CDS             23904..24719
                     /locus_tag="ACHA1B_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HFM8701868.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            24870..26036
                     /locus_tag="ACHA1B_001090"
     CDS             24870..26036
                     /locus_tag="ACHA1B_001090"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM8701869.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            26266..26913
                     /locus_tag="ACHA1B_001091"
     CDS             26266..26913
                     /locus_tag="ACHA1B_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HFM8701870.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            26997..27941
                     /locus_tag="ACHA1B_001092"
     CDS             26997..27941
                     /locus_tag="ACHA1B_001092"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HFM8701871.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            28076..29527
                     /locus_tag="ACHA1B_001093"
     CDS             28076..29527
                     /locus_tag="ACHA1B_001093"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HFM8701872.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            29548..30384
                     /locus_tag="ACHA1B_001094"
     CDS             29548..30384
                     /locus_tag="ACHA1B_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFM8701873.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            30384..31043
                     /locus_tag="ACHA1B_001095"
     CDS             30384..31043
                     /locus_tag="ACHA1B_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFM8701874.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            31169..31858
                     /locus_tag="ACHA1B_001096"
     CDS             31169..31858
                     /locus_tag="ACHA1B_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701875.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            31864..32820
                     /locus_tag="ACHA1B_001097"
     CDS             31864..32820
                     /locus_tag="ACHA1B_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HFM8701876.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            32864..33376
                     /locus_tag="ACHA1B_001098"
     CDS             32864..33376
                     /locus_tag="ACHA1B_001098"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8701877.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(33632..34180)
                     /locus_tag="ACHA1B_001099"
     CDS             complement(33632..34180)
                     /locus_tag="ACHA1B_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFM8701878.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(34269..35450)
                     /locus_tag="ACHA1B_001100"
     CDS             complement(34269..35450)
                     /locus_tag="ACHA1B_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside transporter C-terminal
                     domain-containing protein"
                     /protein_id="HFM8701879.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(35686..37194)
                     /locus_tag="ACHA1B_001101"
     CDS             complement(35686..37194)
                     /locus_tag="ACHA1B_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HFM8701880.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            37353..37544
                     /locus_tag="ACHA1B_001102"
     CDS             37353..37544
                     /locus_tag="ACHA1B_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701881.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            37747..38664
                     /locus_tag="ACHA1B_001103"
     CDS             37747..38664
                     /locus_tag="ACHA1B_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coiled-coil domain-containing protein"
                     /protein_id="HFM8701882.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            38657..39730
                     /locus_tag="ACHA1B_001104"
     CDS             38657..39730
                     /locus_tag="ACHA1B_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701883.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            39878..40396
                     /locus_tag="ACHA1B_001105"
     CDS             39878..40396
                     /locus_tag="ACHA1B_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701884.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            40377..40769
                     /locus_tag="ACHA1B_001106"
     CDS             40377..40769
                     /locus_tag="ACHA1B_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HFM8701885.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            40845..41780
                     /locus_tag="ACHA1B_001107"
     CDS             40845..41780
                     /locus_tag="ACHA1B_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFM8701886.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            41913..42692
                     /locus_tag="ACHA1B_001108"
     CDS             41913..42692
                     /locus_tag="ACHA1B_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HFM8701887.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            42685..43002
                     /locus_tag="ACHA1B_001109"
     CDS             42685..43002
                     /locus_tag="ACHA1B_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HFM8701888.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            43246..44856
                     /locus_tag="ACHA1B_001110"
     CDS             43246..44856
                     /locus_tag="ACHA1B_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFM8701889.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            45013..45861
                     /locus_tag="ACHA1B_001111"
     CDS             45013..45861
                     /locus_tag="ACHA1B_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFM8701890.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT        15238 a         8277 c         8825 g        13553 t
ORIGIN      
        1 attatctatt ttgttactgc ttacattagt agttggctat ttttcgattg agtttatcca
       61 tggattttcg tctgcaaaac agagttcaac tgtgaaaaag gtagagccga aaagtatccc
      121 taccacacta aatgtggctt tgattggttc agatgctcgt tcgaaagacg aaaacggtcg
      181 ctcggattca cttctggttg cacaatacaa ccagaaaaca caacaagcaa aactgatctc
      241 tatcatgaga gattcatatg tcgatattcc aggttacgga atgaataaga taaatgcagc
      301 ttactcttat gggggagttg atttattaaa tcaaacatta aaggaaaatt tcaaatttga
      361 agctccctat tatgcaagta tcacatttca agattttatc gattgcgtta atgaactgtt
      421 tcctggtgga gtcaagatcg atgcagaaaa atctctagat ttagatggcg tatatataaa
      481 caaaggagag caagtgatgg atggtaatac tttactccag tatgctcgat ttcgggaaga
      541 caaagaagga gacttcggga ggatcagaag gcagcagcaa gtgatcaaag ctatctctca
      601 gcagctgaaa gacgtaactt caatattcaa gctacccaaa gcggttggga aattacttgg
      661 tagtatccaa acgaaccttc cagaaagtgt gcttctggat tgtggtatgg atttcctcaa
      721 agacatatgt tagaataaac aggtataaat agtgaaataa aggaatgaca agcaagagaa
      781 ggaggaaaaa atgaaaagaa gtgacaagca cggcaaaaat cgaacaggcg cttatattgc
      841 cggcgcagtg atcttaatag cagctgcggg tggcggttat ttttactacc agcactatca
      901 agaaacccaa gcagtagaag ctggagaaaa gacagttgag caatttgtcc aagctttgaa
      961 caagggagat tataacaaag ctgcagaaat gacatcaaaa aaggcggcaa ataaaagtgc
     1021 attatctgaa aaagagatct tagataaata ccagaatata tacggtgctg ctgatgtcaa
     1081 aggacttcag atatcgaatc taaaagtaga taaaaaagac gattctactt acagtttttc
     1141 atataaagca aagatgaata cctcattagg tgaattgaaa gatctttctt ataaaggaac
     1201 attagacaga aatgatggtc aaaccacgat caactggcaa cccaacttgg tttttccaga
     1261 aatggaagga aatgacaaag taagcctgac cacacaagaa gcagcaagag ggaatattat
     1321 agatcgaaat ggtgaaccat tagcaacaac aggcaaacta aaacaattag gagtcgttcc
     1381 aagtaaactt ggagatggag gcgaaaaaac agccaatatc aaagcgattg cttcctcctt
     1441 cgacttaaca gaagatgcta tcaatcaggc gatttcacaa agctgggtac aacccgatta
     1501 ctttgtccca ttgaaaatca ttgatggagc aacgccagaa cttccagctg gagctaccat
     1561 tcaagaagta gacggcagat attatccttt gggtgaagca gctgctcagc tgattggtta
     1621 cgtgggagat atcacagcag aagatattga taagaatcca gaattaagca gtaatggaaa
     1681 aatcggtcgc tcaggtttgg agatggcttt tgataaggat cttcgtggga caacaggtgg
     1741 gaaattaagc attacagatg cagacggtgt agagaaaaaa gttctgatcg aacatgaagt
     1801 tcaaaatggc aaagatatca aattgacaat cgatgcgaag gcacaaaaaa cagcttttga
     1861 cagtctagga ggaaaagctg gatcaactgt tgcgacaacg ccaaaaaccg gtgatcttct
     1921 tgcgcttgct agctctccaa gctatgatcc aaacaaaatg acaaacggga tctcacaaga
     1981 agattacaaa gcttatgaag aaaatcctga acatccattc atcagccgat ttgcgacagg
     2041 ttatgctcct ggatctacgt ttaaaataat tacagcagca atcggtctcg acaacggcac
     2101 tatcgatcca aatgaagtgt tgacgatcaa cgggcttaaa tggcaaaaag acagttcttg
     2161 gggatctttt caaacaacgc gtgtcagtag tgatgtatca caagtagact taaaaactgc
     2221 tttgatctat tccgataata tatatgcggc acaagaaacg ttgaaaatgg gtgagaaaaa
     2281 atttcgtaca ggcttagata aattcatttt tggtgaagac cttgatttgc caattagtat
     2341 gaatccagca caaatttcta atgaagatag ctttaactca gatatcttgc tagctgatac
     2401 tggatatgga cagggcgaac ttctaattaa tcctatccag caagcagcaa tgtattctgt
     2461 ttttaccaac aatggcacac ttgtctatcc taaattgatt gcagataaag agacaaaaga
     2521 taagaagaat gtcatcagcg aaacagcagt acaaacgatc gtgccagatc tgagagaagt
     2581 tgtgcaagat gtaaatggta cagcacattc tctttctgct ttagggattc cgttggcagc
     2641 gaaaactggt acagcggaaa tcaaagaaaa acaggatgta aaggggcaag agaacagttt
     2701 cttgtttgct ttcaatcttg ataaccaagg ttatatgatg gtcagcatgt tggaaaataa
     2761 agaagatgat gattcagcaa ccaaacgagc atcggaacta ttgcaatacc tcaaccaaaa
     2821 ttatcaataa aaaattgctt tttaagtaca gtaaaaggac tgtggcgtta tcgtcacagt
     2881 ccttttttca aataaacggt tttcacgatg tctctttcac aacttctttt tgatttactc
     2941 acacttcata aacttttttt gtaaaatatt tgagaacaag tggagaaata agtgtactta
     3001 ataaaatcac gataactaaa ggtgaatagt actgtggttc gatcaattga ctttgctgtc
     3061 caatttgtaa aatgatcaaa gccatttctc cacgcgaaat cataccagca ccgaccatca
     3121 atgaactatg ttgagaaaaa ccggcaatct gagcaccaaa ataacctcca agcaatttgg
     3181 tcaaaatcgc tacaagcgtc aatatagaaa taaagagtag ttgttcacta aagtcagaaa
     3241 aatcaacttc taatcctaca ctgacaaaaa atactggtat aaatactgca tatcctaaag
     3301 cctctacatt gtggtatact tcttctttaa cctttgtctg actgacagct atcccagcaa
     3361 aaaaagcacc aatgacagag ctaagcccaa caagatccgc tacgtaagac attcctaaac
     3421 aaataactag cgatacgatg ataatagaag aatttgcgta cactttttct gcaaatgaaa
     3481 gtaggaaagg cgcaatccat ttgactaata agaaaataaa aacaaaataa attagctgtt
     3541 caatcaaaac aagcggtaaa gaagcattgc tagaagcttc ccccgttaga aaagataggc
     3601 tgaaacttag aactaaaacg actaaaatgt catctaccac agaagcaccc aaaattgttg
     3661 atccttcttt tgtattcact acgtttagtt cttttaatac ttctactgaa atactgacag
     3721 aagttgccgc aagaataatc ccaaagaaaa tcgcttcatt tcccgaaact tggaatgctt
     3781 tgcctgtcaa ccagccaaaa acaaccggga agatgatccc aagcaaagca acgaacatac
     3841 caggtcggaa atattttttc aaaagagata aatcactttc cagaccagct aaaaacatta
     3901 ataagatcac accaatctcc gaaaagtcat ggactagaat atcaggtttg acccaattca
     3961 atccagcttg gcctagcaaa acaccaacaa gtaattgtcc aatcactgct gggataccta
     4021 atctccgcga gatatgtgag ccaatcgttg ttgaaatcaa tatcaggcat aaaataccaa
     4081 taaattccat tctcatcatt cctttgtata aaatatagcc cgaacttagc ataacataca
     4141 ttattgaaaa aataggaaaa tatactcaca aaaaaaccaa caatccaaaa gatttttttg
     4201 gattgttggt ttttatacgg tctattttaa taactaaaaa tgattaacgt atagtcattt
     4261 ttcttattct gatgaaattg ataatctcct ggatgcccat gaaaatcaaa ataaagccga
     4321 atatttggaa tagaagcatc aaacttttga atggattgaa caataagacg aatccgccaa
     4381 tcaacaacag aatactacta taaacactcc aacttttagc ttttgtattc atgctgaaga
     4441 acaactggaa caagctgttg atgataacag ctaatccaag aagaatcggc aggatagaaa
     4501 cgattgcagg tgcaaaagca tagacgatca gagctaagat caggaaaaaa agaccactga
     4561 acagaccgat actccaagaa cctgttttcc ttttaaaacg gtaagcctca aaaagattca
     4621 acaacccaag caaaacaaga taggcggtga tcagataacc gataaaatga aaaacagcag
     4681 aagggtttag cacaatcgca atcccagaaa taatataaac agcagctctt aataaggcgt
     4741 atttttgaat attttgttta atcgtctcaa acatataaga aaacctcctt tgacttattt
     4801 taacgtgaac tagtcatttt accaaattaa atgttacaaa atgagcgaag gagaagaata
     4861 tctctggaaa aatcaacttc tgaggatctt ttccattttt ttgccttttg ctagctcatc
     4921 gatcatttta tctaaataac gaatttcttt catcaagtta tcctcgatgt cttctactcg
     4981 tacaccacaa acaacacctg taatcaagga acgtgaagga ttggggacag gggcttccgc
     5041 aaaaaattgt tcgaaagtca cttgtttttg tagttgatat tctagttctg tttgggaata
     5101 acccgtcagc caacaaatga tttcatctac ttcctctttt atacgatctt ttctctccgc
     5161 ttttgctaca tacataggat aaacgcttgc aaaacttgtc gtaaaaatac gattttgcgc
     5221 cataatcagt cacctttctt tttttcaaat tatttactac ttatagtata taagaaaaag
     5281 agaagaaaaa gcgattattc aaaaaaacaa aaaggattgt gacaaaattc ttgtcaccat
     5341 ccttttttcc gctctctgac tttttacaat cttcatagct caagtgcgca tcagataatc
     5401 gaatgctcct aaagctgcag tagctcctga acccattgaa acaatgattt gtttgtatgg
     5461 actatctgta caatcaccag ctgcgaaaac gccggggata ttcgttgcgc catttttctc
     5521 ggtcactatt tcatttcttg gattcatttc gatcgttcca tctagccaat ccgtattagg
     5581 gagtaagccg actagaatga atactcctga aacagctagt gtatgcatct ccatcgtacg
     5641 gcgatcgata taggagagag attctacctg attcgtaccg ctgatttctt tcgtcgctgc
     5701 atgtttgata acagtgacat tcgcaagaga gactagttta tcctgtaaga tttgatctgc
     5761 ttttaattct ggtaagaatt ctagaacata tacatgtttt gctaacccag ccaaatcgat
     5821 tgctgcttca acaccagaat taccaccacc gataacagca atctcttttc ctttaaataa
     5881 agggccgtca cagtgtgggc aataagcaat tcctttattt ttaaactctt tttcgcctgg
     5941 tacattgata gaacgccagt gcgcacctgt cgcgatgatg gcggtttttg ctttaagtga
     6001 tataccgtta gctaagccaa tattaataaa atgttgctct ttatttaagg aaacggcctg
     6061 ttgattcatc ataatgtcga tagggtaact acgcacatga ctttctactt gctgcatcaa
     6121 ttttggacct tctgtgtaag aggtaccaat catattttca atccctagtg tttcaacgac
     6181 ttgtccgccg aaagaatcag cgacaagtcc tgtacggatt cctttacgtg ctgcatagat
     6241 agctgcacta ctagctgctg gtccaccgcc aattactaat acatcataag gttctttttc
     6301 aaacaactct tcttcaatca aagggccagt gattttttca acaatttgtt cgatcgtcat
     6361 gcgtccgcta ctaaattctt ctccatttaa aaacacagtt ggcactgcca tgattttttt
     6421 atcatcgatt tctttttgga acatcccacc ttcaatcatc gtatgagtaa tatttggatt
     6481 taatacagct aatatattca atgcctgtac aacgtcgggg caattatgac aagtcaagct
     6541 aacataactg tcaaaatgca atgtttgtgt tatttttttg attttaagac tcaaagattc
     6601 actgattttc ggtgcccgtc cactaatttg taacatagcc agtaaaaaag aggaaaattc
     6661 atgaccgagg gggataccag caaaaacgat tccactttct ttgccaactg gattgataga
     6721 aaaactaggt gtgcgcatcg aatctctttt ttcccaagag attttaggag acatttctgc
     6781 tatttccttc gtaaattcag ctagtttttg actattttca ctattatcca aactaacaga
     6841 aaaaacaata ggagattcaa tcagtgctaa atattgttcg agattttgtt tagtttcttt
     6901 gtctaacata tccaccacct aaatctttcc aacaagatca aaacttggtt tcaatgtttc
     6961 gccactttct ttccattttg ccggacaaac ttcacctggg tgggtacgta catattgagc
     7021 agcgcgaatc ttatcaatca gtgcactagc gtcacgaccg attccatctg cattgatttc
     7081 catagcttga acgattccgt ctggatcaat aataaatgtt cctcgctgag ctaatccttg
     7141 ctcttcatcc aaaacatcaa aaatacgaga aatctgatga gacggatcac cgatcatcac
     7201 gtattcgatt ttaccgatag catctgatgt atcatgccat gctttgtgag taaagtgggt
     7261 atcggtagag caagaaaaga cttcaacacc taaagatttc aatgtactgt attgttcttg
     7321 taagtcttct aattcagtag gacaaacaaa agtaaaatca gctggataga agcaaagaat
     7381 actccagttc cccataagat ctttttcact gacttctaaa aattctcctt gatgataagc
     7441 atgtgcatta aattcttcga tttttttccc aatcaatgac atagtaaaac ctccaataat
     7501 aattatttat ttataattat tgtaatttag ttggagttgc aaagtcaatg gatattttgt
     7561 tatttaataa agattactca aaaacgaagg ttaattataa aaatagaaga ggtcgcaaga
     7621 aaatgctact gctggaaata ctcgggataa cgttgagtaa cagtttcctg ttctttcagc
     7681 atcatgtgta agtgcaatcc cgtttgaaat cgagcttctt ctggtttttt atcaactaaa
     7741 gccttgagta aatcataatg ttgttccatg atcgtttccc atggaagccc ctgaatggtc
     7801 actcgtaacc agcggaaacg ttctaaatgg gtattatggt catctaacca gttccaaact
     7861 tcttttcttc ctgcaatttc gaaacaagct tcatgaaata aattatctgc acggaaaaaa
     7921 gcgcgttcgt catttatttt gactgctttt tcttgttctt ctaaaatcgt ttctagcact
     7981 attcgtgttt gtgtgtccaa tttggaacaa cattcaatca tgatttgctc ttccaactgt
     8041 tctcggacaa agcgagcatt ttctgcagaa acaagattaa ttttggaaac atacgtacca
     8101 ctttgaggta tcgtatacac gagttcttgc tgacgtagtt gaatcaatgc ttcgcgaatg
     8161 ggagtccggc cgatagcaag atgttcctcc agtgcctttt cagatatttt ccttccaggt
     8221 tctaagtcag catagataat ttgtttacga atcgcttgat aagcttgtga ttgcaagctg
     8281 cttttcatct ttattcctcc aaaatcattt ctatgaacgt agtataacag aagaggtctg
     8341 aaaaacaatc tggtatgtca cattaactag taaatttgta taaatagtaa aattttggtt
     8401 gacatagcga tttttattgt ataaaattca cttgaataca aaaactaata tgttagttta
     8461 ggaggggaaa aatgattgat ttaaacaact ggaggaactt tatccctgaa ttatctcaaa
     8521 aagaagtaga aatacctcat tttgaccgtg catcattaag agaaaatgga caaaaaaatc
     8581 ctgtctggat ccatttcggt ggcggaaatc tttatcgagg atttcatgca gaaatcgctc
     8641 aacgtttagc ggatctaggc gaattgtcca ctggtgtcat tgtttgtgaa acattcgatg
     8701 aagaaataat tgaaagggct taccaagatt ttgatgattt gattcttgaa gtggtcatgc
     8761 caagcagtgg agagttcgtc aaacgtatat tagctgcgac agctgacagt ctgtattgtc
     8821 atccagattg ttctgaacac tttgataaga tgattcgaca ctttgaaaat cctagtttac
     8881 aattagttac ttttgctatt actgaaaaag gttatcgatt gaaagataca aataataaat
     8941 atataggacc gattgcagtc gatataaaaa atggtccaaa gaagccatca catacaatga
     9001 gtattcttgc tgcgctactt tataaacgtt ttttatctgg agcttggccg attgcacttg
     9061 tctctacaga taatttttca caaaacggta gtcaattacg tacttctttg ctaacgatcg
     9121 caaaagaatg gcaaaaggaa ggttatgtac aaaatacatt tatccaatac ttatcgaatg
     9181 aagaaattgt tgcgtttcca tggacgatga ttgatcgtat caccccgaat ccttccttgt
     9241 cagttagcaa aatgttggca aaagagggct tttcaaatat gtcgattttc caaaccgcaa
     9301 aaggaaataa tattgctcca tttgtcaata cagaggacat ccattattta atcatggaag
     9361 atcattttcc caatggacgt ccgaaattcg aaaaagctgg ggtattcttg actgatcgtg
     9421 caacggtaga taaagcagat acgatgaagg tgacgacttg ccttaatcct ttgcatacgt
     9481 ctttagctat tatgggttgt ttactggggt ataggagcat agctgaggag atgaaagatc
     9541 cagatttatc gctgctagtt tctgaaatcg ggtacaatga aggcctccca gttgtggagt
     9601 ctccaggtat cattgatcca aagatctttc tggaagaagt aattactgtg cgcttttcta
     9661 atccaaatat tcctgatatg cctcagcgaa tcgccacgga tacctctcaa aaggtggcga
     9721 ttcgttatgg tgagacgatt aaaaaatata tggaaataga agttaaagac ccgcagacac
     9781 ttgtattcat accattgact ctcgctgctt ggcttcgata ccttattggc attgatgatc
     9841 aaggaaaacc attcatcccg agtccagacc cactattgac agactttcag cataagcttt
     9901 ccgatattca actgggtacg caagatacat cacatattca tgagaaaatg gctcctattt
     9961 tgtcaaataa agaaattttt ggtgtagatc tttaccaagc agagcttggc agaaaaatag
    10021 aagaaatgtt catcaagatg gtagcaggac cgaatgccgt acgaaaaaca ttacaggatt
    10081 acttacaaga acatggagga aatttatcat ggaaatgact tttagatggt acggatcaca
    10141 ggaagaaaag attaccttag atgaaatcag acagattcct gcggtcaaag ggattgtagg
    10201 cacattgatg gatataccag taggagaggt atggcccagg gagaggatca aagaactaaa
    10261 agaagaaatt gagtctcgtg ggttaacact aaaagtaatt gaaagcgtca atgtgcatga
    10321 tgccattaaa attggattac cttcccgtga gcagtatatc gaaaactata agcagacaat
    10381 ccgaaacttg gcagaatatg gaatagaagt catctgctat aattttatgc ctgtatttga
    10441 ctgggtgaaa tctgaccttg actaccgctt agaagacggc tcatccacgt tagcttttat
    10501 atctgatgat attccagatg atccaagaga aatcgtcgcg cgcatcgaac attccagcaa
    10561 tgaatttgaa ttgccgggat gggaacctga gcgcttagct catatcaaat ccttgcttga
    10621 agcctatgca tcagtagacg aagaaaaact tcgagaaaat tttgcctatt ttctccaatc
    10681 aatcatccca acatgtgaag aggtaggggt caaaatggct gtacatccag atgatccgcc
    10741 atactcgatt tttggattac ctcgaatcgt aaagaatcga gaagatttag attggttgtg
    10801 ccgcatagta gacagccctt ataacggaat cactctttgt acagggagta ttgcagaaga
    10861 tccagaaaat gatgtatatg ggattttagc agaattttgt caaagagatc gaatcccatt
    10921 tgcacatgtt cgaaatatta aatttttagc taatcgagat ttctatgagg caccgcataa
    10981 atccgaatac ggttcattag acatgtaccg catactaaaa acaatgtatg acaacggatt
    11041 taacgaatac atccgtcctg atcatggaag aatgatctgg aatgagacag gaagaccagg
    11101 atacggctta tatgatcgag cattaggtgc tgtttatcta aatggattat gggaagcaat
    11161 cgaaaaagga aacaaaagta aagataatta gtgaaaaaaa ctgtaatttt attatgtaaa
    11221 taagaaggat gttcaaattc ttgatacata aatccggagg ttgttaataa gcattcggat
    11281 ttatgtatct tatttggtct aggaagtaac ttgattttct tttttcgatt gatccatgag
    11341 tgcttcttct tttaattcaa agatatattc tgagatcctc ataatcactt ttttccagtc
    11401 ttctggtgtg atgattcctt ttaaaatata gatttttttg atatgagaag gcaattgttt
    11461 caaagggcag tcgctgataa cgatgttgca gttctccata aaatcatttt gtattttgat
    11521 cgattcattt gaaaaaattt gttctatctt aacgatcaga tctttactga tataaaaatc
    11581 acgcgtatag ttcacaccaa tcacaattcg cggctgtttt ttgtagcgat catacaaatg
    11641 tactaggtct tcaaccatcc attgcacatt ttccttttct aaaataactg gtaacaagtg
    11701 ttgattttgt tctctgaaat ccatataaaa ttgttcaatg gcggtttgga cttctttcaa
    11761 cacgctatgt tcttgataaa gcatgaaagt aggaaggggc gtatttggtt gattgaagtt
    11821 aagaaatcca ttataaagtt tatttcgtgc gaatgccaat gagtaaagaa tcttttcttt
    11881 ttcaggtata aacaaatcaa atacagtaca aaaggactcc accatttctc ttgaataaag
    11941 aacatgagga acgtttgctt tttttaaaag tttgtattgc tccaagcttg tttcttccga
    12001 ttcgattttc gtgatagaaa gtcgagctaa aatattcact aagatgcgtt gttcgcgaca
    12061 aattggcaga ttaggtcgca aaatatctac agagggatca ataaaaaagt caatatattc
    12121 atactctgtg aattcttttt gtacgtcttt cacagaagtt gcaggaaaat tctctttaca
    12181 tatttttaat agaaaatata atttatctat cataccgcta tttagtcggt caagtacttc
    12241 ttttttaaaa aaagtattca tcataaaagc cactacttgc ggatcttcat cataaaattc
    12301 tgtagcagta cttgaaaaga tgttccaata aatatctaat gctgcatatt gaatttgtac
    12361 ctcttttcca gaaaaagact ttctgccatt attagaaaag gagatagaca aaccgtacaa
    12421 tgctaaaaat gcattaatct ttttcatttt cgtatacaaa taagaggcac tatagtttgt
    12481 ttgctgactt aaactgataa tcgaatttgt ctgacagctg aacaaagaag tcaagatctg
    12541 ataactgact gattcgttgc agtatcttcc aaatagacga taatagcagt aagccggatc
    12601 aattccttca aaattcaact ttaaaaaagg tttttgctta tcaatatgca gttctgttag
    12661 attgagacgc tcaaagtctt gttctaattc tttgatgtat agtaaaaaat ttgattcaga
    12721 catatggaaa tgatctgcta aatattgtgt agtaataaag aaacgatgtt cagataggaa
    12781 aagaaaaata tctaattttg tattgctttt tttcttcaag agaaacgttt taatcgcttc
    12841 ttgagtttgc atgaaagagg ctccttttta cttaaattgt taaaacttga aaatattact
    12901 gtttttttca taaatttaga caaaaaaaca gtaaacatat aggtagaatc tctactatct
    12961 tatttcttgc atacaaaaaa atcaaggagt gagagagtta tgagatattc aaccatctta
    13021 atatcaacat ttgcagcctt aagcttatcg cttactataa atcagacagt ccacacagag
    13081 gagatagaaa cagccaaatg gacagaaacc aagtgggcca acgtcaatcg aattaccttt
    13141 caggatgaat tttcatcctt caattcagga gtcgcaaaat taagaaaagg acaaacagcg
    13201 accatcaaag caaaaattga ctattcagga gacttagcac ctatactaca atcagctgtt
    13261 acatttgaga atgttgatcc cgctttgtcg attggctatg acgagaacac tttgactatc
    13321 caacacaagc aagcgatatt taccttcacc gttacattaa atcaggactt gttaaaacca
    13381 gcgcttttta ctgtcaaggt atcagatgga ctaccgaacg atcatcatca tttaacgccg
    13441 tatagtcagc ggcagacaat tgagcaagat tcagctatcg actcaggagg agatcttgtt
    13501 gaagaaccaa cagataaacc agaaaatgaa aataagccag aagtaccgcc tacagaaaat
    13561 ccagacggag aacagaaacc ggaaatagaa cctggagaag aacccgatac agaaactcaa
    13621 ccagagccag acaatgaatc aaaacctgaa ataacccctg gagaaaaacc agatgtagac
    13681 ccagaagaaa aaccggatgt gactccagaa ccagatacgg attctggaaa ccaaacagta
    13741 ccggaaacaa atccagacac agataatgaa actgaaaatc cagaaaaacc agaggcagcc
    13801 ccagaagaaa aaccagatgt aactccagaa ccagatacgg attctggaaa ccaaacagta
    13861 ccggaaacaa atccagacac agataatgaa actgaaaatc cagaaaaact agaggtagat
    13921 ccagaagaaa aaccagatgt gactccagaa ccagatacgg acgcaagaga ccaaggaata
    13981 ccagaaaaaa taaacaaaaa aacaattcaa gaggatggaa aaaaagagag taaaaaatca
    14041 aatctagcaa ttctaaaaat aaatgaagag cagctgaata aaaaatcacg aatatttgat
    14101 agcgcccaat cagctgaaac cttaaaaagt agcaaggata caacctttgc tagtcctgaa
    14161 acgaaaaata aacagctacc aaaatccgga gagtcacaaa acaaagttat actgtggagc
    14221 ggaatcattc tattaagtat agcaacaatg ctttctgcaa aaagatttaa acaaaacaga
    14281 tctctctaac atttgaataa tgtctgtgaa cgcatttttc aaataaaaag aaatatccag
    14341 aaaacgaccc caaaatacca gattgaaatc tgatatttgg ggtcgttcat actttatctt
    14401 tcttcatatt tattttaagg gatatctgtt tcttttggaa gatggttcgg gatctttttc
    14461 actttcaata catctaaaaa gaaggtaaag atcggaatgc cgacaatcaa gccccaaacg
    14521 ccaaagaacc gttcgctaac aagtaagacc acaaatgtat aaaaaatcgg cagttctgtt
    14581 ttgctggaca tcaacttcgg attcagcaca taagactcaa ttagatggac aatcaaaatc
    14641 gtaatcagga tataaacaac atctcggatg cctccttggg aataagctat gaaagataga
    14701 ggaatacaag aaatgataac acctgctact gggatcagac ttaaaatgaa aatcatgatc
    14761 gctaaactca gcagctgatg aaagccaaat acagccaagg cgattgtagt gagcaacgtg
    14821 tttaaaagag cgataacaaa ttgagcttct aataccaaac caaatgtatt gacaaactta
    14881 tcggcaaaat agtaaatatc ttgaaagaac caagaaaatt cactttttaa aaacaatctt
    14941 gagaatacaa ttgttttttt cttttcaatc ataaaaaaga aacttaagat gaatgacata
    15001 gcaaacgcca ctgccatttt tcctatatcc tgtaaatagc caagcgcaat cgaagcgcca
    15061 ttttgaagct gttcaaaaaa atcgtttcgc tcaatataag tatggatata ttgtaaaaca
    15121 ggatctgcat cttttggctg atgctcgtaa aaatcaataa cggactggat catatcaaat
    15181 gtttgatgaa taagcatcgg gatatacttt gtgaatgcca gatagataag gtaaacgatc
    15241 agtgtataaa tcatgatagc taaaacacct gtagggattc ggacaaatcg ctgaatgatt
    15301 tgaacaagat gaatcatcaa ataagtaaag ataaatgtga gcaaaatggt tgtaatcata
    15361 cttctaacta agaaaagaac aaaaacgaca aataataaaa cagtgagacg gcgtattttt
    15421 tcattcgcca aaaaacgctg ataaacggtc aaatcgacaa cctccaaata acaaaaaata
    15481 aacacgttat tcattatatg atggaatatg aaaataagaa agagaaagag caaaaagaaa
    15541 aaccgctaaa tgacgttatc ttatgagttg gttttcctca taaaatcgtt catctagcag
    15601 tttcagccct ttttctggtc ttgatgaaaa ttatctagca tttttcgggt cagatgttgc
    15661 agtgtatcca attcttcctg ttcaagtgga agataagact tgatcttttg tggaatacct
    15721 tctgcttgtt tttgcaacgc agcaccttga ggagtcagcg taacatttac gattctttca
    15781 tcacccgttt cacgctgacg attaatataa tttttttctg ctaacttttt tagtaaggga
    15841 gtcagcgtac cagaatccag acacaaatca tttcctagct ctttcactga agtctttttc
    15901 ttttcccata aaactaacat cacaagatac tgggtatagg taagattcag cggcttgagg
    15961 agggaagtgt agtgtctaat gatttcctta gaggcggcat ataaaggaaa acatacttga
    16021 ttaactaaat atagatcttc catttttcca cctccgctgt tttactatag tgtatcatag
    16081 cggatttaca caaaaaagtc tattcactaa ctgctttcag agtaacttct atatttccag
    16141 ctgtagcttt tgaatacgga cacactttat gcgctgcctc taataattct tgcgtttctt
    16201 ccagagaaag accttcgata gatccttcaa tctctacacc taagacaaag ctcgtttcac
    16261 tttctgaata aagggaaact tgtgcactga cagtagaagc cccagagata tttttttgct
    16321 gtttgatcaa ttctaatgca ctgttaaaac atgcactgaa accagctgca aacaattgtt
    16381 cagggttggt tgcattttcg acgcgtttac caggagctgc aatattcaat tcgaatgtac
    16441 gatcgggatt atgaacttct ccagagcgtc cgcctgtgtt gatcattttc gtagaataca
    16501 tttttttcat aaaattacca cctttaatta tattttatac aattgaattt tacacaatat
    16561 aattgtggaa agcaaagaaa tggattggca taagataaat aagagaaagc acatgaaaca
    16621 gacgcgcttt ctcgaatagc aaacatatac aaaaaaatat cagagacaaa aactaatctc
    16681 atcataaaca ttacatatat ttctcaaaaa gttgttttct ttcttcaaaa cttacttcac
    16741 gatggacctg atgaagcatc cataaataac caaaaggatc tctgaacatt gagttagtca
    16801 caccaaagtc catcatttct gtcatttctt gaatctctac acagccattt cgtaatgctt
    16861 tattatgtgt gtcctcgata tcagagacga tgatattgaa ccagatcgta tttggatgtt
    16921 cagcagtagg agcagtcaaa ccaagagacg tgttttcatc cagcatatgg aatctcgtgc
    16981 catacaaggt aaaaatgact tcattattgc ctctagggta atctgttgcc tcaatcagtt
    17041 gtatttcatc aaagattgtt tgatacagtt ctagtgcttt caaactatca tttaatacaa
    17101 aatctatttc cgttccttta tgcataaaga tctcctctcc ttttcagtcg aacagttact
    17161 agattctttt attataccag ttaaagaaaa cgcattcaaa aaaatagcgg atttacttac
    17221 caactcattc gattggatga taagtaaatc cgcgtcccat tacttctgct acgctgctga
    17281 caatgacaaa ggcacttgga tcgatttctt ctatcaatgg tttcattcgg gaaaattcat
    17341 gatcagtcac aacgatcaat aaaacctctt ttgactttcg attatacccg ccttttgcct
    17401 ctagcagggt aaggccacgt ccaatctcag cacttaagcg aaggcggatg tcttccaaat
    17461 aatgttcact catgaccata acagatttct ttcgattgat acctgtttcg atataagtca
    17521 tgacaattga agtgattgca atagataaaa tagcataaag aaactcttct attccaaaaa
    17581 caaacagatt aagagaaaca acgaatgcgt ctgtaaaaaa taagccaatc gaagtattca
    17641 agtggaaata ttttttaaaa atgaggggag ggatcgtcgt accgccgcta gaagagttgt
    17701 ttttatataa aatcgcaact cctaaagcaa aaatcgcact tccaaaaatg acagacaaca
    17761 accgatctga agtaatcatt gtttctggaa ctattgcaat gattaaagga aaaaacaagc
    17821 ttccgaaaag tactttaaaa aagggttttt tacctaaaaa tagaagagct agtaccaaca
    17881 taacgatatt caacactaaa ataactatag ctcggtcaaa tcctaaaaca gcttccagta
    17941 atattcctag accgctgaca cctccagcag caatatgatg aggccctaaa aacatattga
    18001 tagcgactcc taatatgaag agggcaaaaa taatcttaat gtatgtccat ataaattgtc
    18061 tcgtttcttt catttatcca cttccttaat tcattaataa tactcttatc ttattataac
    18121 ttacttttca ccttaagtta actttaatta ataaaaaaat taggctagtc taaattatta
    18181 tgtttcattc ttctagaata tacttctacg ttaaaaactg ttaaaaaact tttactttag
    18241 aaaattggag aaattgatcg cttaagataa attcaggaca ctaaatagta caggaagtag
    18301 attaaaactt ttaaaagttt taagtctatc tatttggcaa gtttaaaaaa taaaaattcg
    18361 gtatcaaaaa actgttaccg ataacatttt tgaaagcgtt gtcttttgtt tctctatcac
    18421 ttatagtgat gacgtcatat taaaacacaa ggaggaaatc aatggataca gctgcaattt
    18481 atcatcgacc ggaaagtgaa tatgcatttc tatatacgaa tacaagattt cgtattcggc
    18541 ttcgtactag gaaaaatgat atcaaaaaag tatatgtgct ttgtggagat ccatatacca
    18601 taacaactga aaaatggtat caaaaacaac gaccaatgaa aaaatgtcta agtaccaatg
    18661 ttcatgatta ttgggaaatt gaagtgacga gcgaaacaag gcgcttacag tatgcgttcc
    18721 atgttgttgg ggaagataac acggactgtt tttacggtga tcaaggaatt tttccttatc
    18781 gagaaaatgt gattactgaa ccaaattttt attttcgaat accttatttt catcaaatcg
    18841 atcgattcac tattccagaa tgggtaaaag aaacagtatg gtatcaaatt tttcccgaaa
    18901 gatttgcaaa cggggacaaa gcaaatgacc ccgaacacac tttaccttgg ggaagtaaag
    18961 atccagaccg agaagacttc ttcgggggag atttgcaagg tgtgagggat catttggatt
    19021 acttgacgga ccttggcgtc aatggcatct atttttgtcc catatttaaa gccacatcca
    19081 atcataaata cgatacgatt gattattatg aggtggatcc cgcttttggc gataaaaaac
    19141 ttttaaaaaa cttgattgat gaagcacata aaagagggat acgtatcatg ttcgatgctg
    19201 tattcaatca tatgggtgtc cattcaccac agtggcaaga cgttctcaaa aacggagaaa
    19261 aatcgatcta taaagactgg ttccacatcc gttttttccc agtagattct tatcagatga
    19321 ctgacttacc agaaactgct gaaaatatcc catatgatac ttttgctttt actccattca
    19381 tgccgaaact aaatacagca aatccagaag tgcaaaaata tttgctggat atcgcaactt
    19441 attggataaa agaattcgat attgatggat ggcgtcttga tgttgctaat gaagtcgatc
    19501 atcatttttg gaaaaaattc agagaagcag ttacagaaat caaaccagac atctatatcc
    19561 ttggagagat ttggcattcc tctcaagctt ggctgcaagg ggatgaattc catgcagtga
    19621 tgaattatgc attcacagat tcgattaaag attattttgc aaaaaagaaa atcacagctt
    19681 cacaaatggt cagtggaatg aatcatcagc aaatgcttta cagagatcag gtgaacgaag
    19741 gaacattcaa cttattagat tctcatgata ctgccaggat cttgaccctt tgccaaggta
    19801 acaaagaatt gatgaagtct gtgatggcct ttatgtttct tcaaaaaggg tctccttgta
    19861 tctattacgg gacagaaata gggatgactg gtgaagatga cccggattgc cgcaaatgta
    19921 tgatatggga gaaggaggaa caagatctag agctattcgg ttttataaaa gaacttgttt
    19981 ctctaaggaa acagttgtct aagattattt ctgaaggttc tactcagtgg ctaatagtat
    20041 atgatcgtga agataagctc tatttcacac gggaactaga gggacagatc atctatgttt
    20101 actttaatca gtcaaaagaa ccttgggtag tagaacagga aaatgaggtg attcttagtc
    20161 aaaattgtca gttgttagaa gacgggaaag cagagatacg acaatacgga tttttgatca
    20221 tgtgttgaaa actgttaccg gtaacaacaa gaaagcgttt gcaaatgaag atttgtgccc
    20281 attataataa gggtgtaaca gcacgttgaa tacacaggag gaaatgaaga tgaaaaaaag
    20341 aagtgtgaaa cagttgggtt tagggttaat ctctttagga atcttaggcg gattagcggc
    20401 ttgtggcaat ggtaactctt cagcagaagg ggaagccgat gaaggaaaaa cgttaacagt
    20461 ttccgttgat tctggatata aagattatat aaacgaaata aaaaacactt tcgaaaaaga
    20521 aaacgatgtg aaaatcaagc tagtagaaaa ggacatgttc gatcagttgg aatcattagc
    20581 gttagatggg cctgctggaa agggacctga cgttatgatg gcagcatatg accggatcgg
    20641 tgcgttagga cagcaaggac atctggcgga agtaaaactg ggaaatgaag cagcttacga
    20701 tgaaacagac aaagcccaag tgacttatga tggaaaaatc tacggagaac ctgcagtaat
    20761 cgagaccctt gttttgtact ataacaaaga tttagtcgat acagcaccat caacgtttaa
    20821 agatttggag aatctatcca aagacagtcg ttttgctttt gagtcagaag caggaaaaaa
    20881 tacaggattt ttagctaaat ggactgactt ttattattcc tatggtttaa ttgcaggtta
    20941 cggtggctat gtatttggtg atgatggcac aaatccttca gatatcggtt tgaataatgc
    21001 aggtgctgta gaaggaatct cttatgcaac agattggttc aaaaatgttt ggccaaaggg
    21061 aatgcaagac ataaaaagtg caggagactt cgccagccag caattcatgt ccaataaaac
    21121 tgcagcaatc attgacggtc catggcaagc gcaaacatac aaagaaaaca atatcaatta
    21181 tggtgtagcc aaaattccta ctctaaataa tggacagcct tatcaaccgt ttggcggagg
    21241 aaaaggatgg gtagtcagca attatgctaa aaacaaagac ctctctcaaa aatggcttga
    21301 ttatgtaacg aatcaggaaa atcaagaaaa attctttgaa atggtaaatg aaatccctgc
    21361 aaaccaacaa gctagggaaa cagcaaaggc taaaaacgat gaattaacaa cagctgtgat
    21421 tgaacaatat gaaacagctc aagcgatgcc aaacatccca gaaatgggcg aagtttggac
    21481 aggtgcagaa aacttgatgt tcgatgcagc atcaggttca aaaacaccaa aagaatccgc
    21541 agatgaagca gtaaaaacaa tcagtgaagc catagaacaa aaatactgat taaaatgata
    21601 accgtccatt tttataaaaa atggaacagg tgcttcagat aaaagtggca agagcgagat
    21661 ggaaaattat cttgctcttg ttgccattat cttaaaagca gtttgcggtt tagcaagttt
    21721 agagggggca ttcagatgca gcaagataaa acaagcaata tcaacgaaaa aaaaatcacg
    21781 ctttgttcac ttattccagg gatggggcag tttgtaaatg gccaagcttt taaaggtatc
    21841 gtttttttcg ccatattcgt cctattcatt ggtcagatgc ttctgggcgg atttcatgca
    21901 ttggtaggat tggttacttt gggaagtata ccaatggaag atcattcatt atttattttg
    21961 attgaaggca ctttgcaatt catcattaca atcattttct tgatttttta cggtttgaat
    22021 cttttagacg cttatcgagt agcgaagatg cgtcaagagg gcaaaaaaat caatcggacg
    22081 atgaaggaag tcatacataa tataggtgat gaaggttttc cttatctatt gacacttccc
    22141 gcttatcttc tcatgatttt tacgatcatt ttcccagtcc tagttacatt gttcactgca
    22201 tttactaatt atgacttcaa tcatattcca ccagccagtt taattgattg ggtaggggct
    22261 aaaaactttt ttagtatctt ctttttaagc tcatatcgta atactttttt tgcagtcttt
    22321 tcgtggaccg tgatttggac tttatgtgca acaactttgc aaatcaccct tggtattctc
    22381 acagcggttg ttgctcacca gaaatttatt aaattcaaac gtattttcgg tatcattttc
    22441 ttattaccat gggcggtccc agcttttatt actatcatga gtttttcgaa tatattcaac
    22501 gatagcgtag gtgccatcaa tactcaagtg attcctttca taaaccagct tccttttgta
    22561 gatatcagtg caatctcttg gaaaacggac ccgaactgga cgaaagtagc aattatctta
    22621 gtgcagggct ggttaggatt tccctatatc tatgtgatgg ttacaggaat cttacaatcg
    22681 atttcagaag acttatatga agcagcaaaa atcgacggag caaatgcatg gcagcgcttt
    22741 tcaaacatca cgcttcctgc tgtcttccta gtggcagcgc caacatttat tacacagtat
    22801 acggggaatt tcaataattt ctccatgatc tatctgttta acaatggtgg tcccggaagc
    22861 gtaggcggag gagctggttc tactgatatt cttatttcct ggatctataa acttacgact
    22921 ggaacttctc cgcagtattc tatggcttca gcaatcacgt tgattatctc cgtcatcgtt
    22981 atctgtgtgt cattgctggt atttaaaaag acaaatgcgt tcaatatggg ggattaacaa
    23041 tgaaaaaatt tcattcgagt gctcgattcc aaaaacgact ttctcacttt tttacttact
    23101 tttttctttt aatactgtca gtcattatca tctatccgct tttgatcaca gcaagtactg
    23161 ccttcaagtc aggaaatatt gcagctttta gtttagatct ttcaagtgac tggactttag
    23221 gaaactttac tcggctattc agtgaaacac tttacgggac ttggtataaa aatacattga
    23281 tcatttctgt cctaacaatg atcgtacaag tgactgtagt aactttggcg ggctatactt
    23341 atagtcgcta tcgttttatc ggccgcaaat caagtttgat gttcttttta gtgattcaga
    23401 tggtaccgac tatggcagca ttgactgcct tttatgtcat ggctttctta ttagaagcgc
    23461 tcgataagta ctggttcttg acaatgatct atataggcgg tggaattcca atgaatactt
    23521 ggctgatgaa aggatacttt gacactgtac caatagattt agatgaatct gctaaacttg
    23581 atggggcagg gcatttcagg atttttttcc agattgtatt accgcttgtc aaaccgatgc
    23641 tcgccgttca agcattatgg gcttttatgg gaccttttgg ggatttcatg ttagctaagt
    23701 tcctgcttcg aacacctgaa aatcagactg ttgctgtcgg cttacaaaca tttatttctg
    23761 atgtgacaaa ccaaagagtc tctctttttg ctgctggggc aattttgatt gcactaccga
    23821 tttgtctatt attcttcttt ttacaaaaga actttgttac cggcctgaca tctggcggaa
    23881 caaaaggata ggagcagagt atcatgcaaa catttccgtt aaactatttt tccgcattac
    23941 gtacgccaac tcaagtgttt gcgggacgca aactattatc atggcctaaa tttttcttga
    24001 tatttgtatt tttagtttcc ttgatggtca tgcctgtgac tcttttttat gccaatcaga
    24061 tccaagcgat tccattagaa caatttctat ccgttcattc gctgatcgat gaacaaggaa
    24121 cccaaaaatt ttctgaactt gaattatctg aaactgggtt acaagcatcg caacaaacga
    24181 tagctgtgac ccctgaaatt ttggtaggtg tgtctttatc tgagaaacaa caatccgatc
    24241 atggaacttt tattgatttt gagaaggaac aatgggtgat ccaacaaaag gataaatctg
    24301 gtatacgccg ctatacgatg aattatagcc catctttcca accagattct gtacgtacgc
    24361 ccgaagattt ccaacgattt ttagaaagag aattttatgc cagtaatcgt ccaacaatca
    24421 ttttatctta tagtttaagt cttggtcttg tcctatttgt catgacgagt ctcattttat
    24481 tcggggcttc ctttttcttg tggatgacaa gaaaaagcca actttcatcc attcatacat
    24541 tcaaagagag tgcaaatttg atgctgaatg ttatgggaat aggttccatg gcagcagcag
    24601 ttgtagggtt tatccacttt gactttatct tgatgctaag tgtccaaaca acgataactg
    24661 tcttgctgct tttatgggtt tttgtcaaaa caagattcaa agataagcgt gtcgaatgac
    24721 aagtttaagc gatttatgcg acaatgaatg tgaaaaaaat gaaaaataaa gtagtttttg
    24781 aaaaatttct gaaaaaatta aacttcttag ttgattcttt tcttttttag tattaacgta
    24841 atagggtagt ttttttaagg aggaaaatca tgttagagaa aactttatac aatcaattat
    24901 tttcacgttc tttctcgctc cctgtcgaag taaattattg ggacggtaca acgaaacaat
    24961 acggagatac ggacactcct ccccaaatca aaatcaatat ccatgaagaa atcccaatga
    25021 aagagattac aagtaacgct tctttggcac taggagaagc ctatatggat catcgaatcg
    25081 agatcgaggg aagtatccaa gcattgatca acgatgctta tcagcaagca aacagctttt
    25141 tacgaggaaa agattatcta aaatggctgc caaagaaaga aaaacatacg aaacaaaaaa
    25201 acaaagaaga tatccatgcg cattatgact taggtaacga cttttataaa ctttggctag
    25261 atccaacttt gacttattct tgtgcttatt tcaatacacc tgaagatacg ttggaacaag
    25321 cacaaatcaa taaagtccat catatcttag acaaactctt tatcaaagaa ggcgaaacgt
    25381 tgcttgatat cggttgtggc tggggaacat tgatgttcac tgctaccaaa gagtataatg
    25441 tcaaggcaac tgggatcaca ctaagtgaag aacaatacga tttgattacc aaaagaataa
    25501 aagaagaaca tttagaagat aaatgccgtg tattattaat ggattaccgc gaactaaaag
    25561 gcgaaacgtt tgatcatatc acaagtgtag gtatgttcga acatgtaggt tctgaaaatc
    25621 ttgaaggtta tttcaaagtg gtaaaagatt tattgaaacc aaaaggaaca gctttgatcc
    25681 atggaatcag ccgacaacaa ggcggtgcga caaatgcttg gatcaataaa tatattttcc
    25741 ctggcggtta tgtccctggt gttactgaat tagttgataa tattacaaaa aacgatttgc
    25801 aactgattga tttggaaagc ttacgtcgtg actaccaatt gacattagaa cattggacaa
    25861 agaattttca tcaagtccaa gatcaagtca cgaaagaaat gggtgattcc ttctatcgaa
    25921 tgtgggatct atatttacaa gcttgtgcag cttcatttga atcaagtaat atcgatgtga
    25981 ttcaatattt gcttgttcaa cctggaaaca atgacatccc aatgcatcgt gcataattga
    26041 ggcaaaagta ctgtttaaag actatttaaa aagaagctaa gttttatgat gctccagaag
    26101 tgaacttttt tgtctaactt ctaggattgt ctctaaagct tagtttcttt ttctttatat
    26161 tttcataata aaagtttggt tctttaattt ttaaacatga cagaaaattt tttcttcgtt
    26221 atacttgtaa tagaatacta ttttataaca aaggggatcg aatcaatgaa aaaaactgtt
    26281 atttatacta gtttatttgc agctttgttt ttagctgctt gtcaatcaaa taccaatcaa
    26341 ggcacatctg ggaatacgtc ttccagtagc gaacagcgct cttcacaggt atcggactcc
    26401 tcaacaaaag caagcacatc ttcgtctagc cagacaaaaa gttctagtga agcaagtact
    26461 cagtcagata tcaaagtgtc tgcagctcgt gcgatcgaat tgttccaaga taaataccca
    26521 gatactgcaa ttactagttt ggaattagat agtgattggg gatcttactt ctacaagata
    26581 gaaggtgtcg atgatcaaaa agaatacgaa gcaagaattg atgctcaaaa tgaaaaaatg
    26641 gagacagaga atccagaaac tctagatcga gatgaacaaa atggtcaaaa gaaaaaagaa
    26701 gatggtctgg atgttgataa attgatcacg attgaggaag cagcaaaaat cgccgtcgac
    26761 aaagtaggaa gcggtacggc aacagattgg gatttggata aagatttagg tactacttat
    26821 tgggaagtca aagtaaaaga cggcaatcaa agtacatcag tcaagatcaa tagccaaaca
    26881 ggcgaagtac tgtcaactga acaagatgat taagaatttc ttcggaaaac aagagttgat
    26941 ttttctttta gtcatgatac actagacaaa ataacttgtt tgaaggagcg atttacttga
    27001 gtttagaaac gacctttgcc aatcatatct ttgccaatcc tttgatgaat gcatctggtg
    27061 tccactgcat gactacccag gaattagatg aactggctca ttcagaagca ggagcattta
    27121 tcactaagag ctgtacgatc aatgaacgaa aaggaaatcc cgaaccacgc tattttgatg
    27181 ttcctttagg gagtatcaat tctatgggac ttccaaactt aggtttttct tattatctag
    27241 agtatgctct tgcgtatgaa aaagtgcagg aaaaccaaaa tcaaccgtta tttttttcca
    27301 ttgccgggat gagtgtccag gaaaacttgg aaatgcttga gaaaatagaa aaaagtgggt
    27361 ttaatgggat cactgaatta aatttatctt gtcccaatgt gcctggaaaa ccacaactag
    27421 cttacgattt tgaggccact tatgaaacac tgaaagaagt attcagcatc ttttctaagc
    27481 cgctaggaat caaattgcct ccttattttg attttgctca ttttgatcag atggctgata
    27541 tcttgaatca gtttccattg acctatgtca atgctatcaa cagtgtgggc aatggtttgt
    27601 atatcgatac agaacaagaa gcagtagtca tcaaaccaaa agaagggttc ggcggcattg
    27661 gcggagagta tatcaagccg actgctttgg cgaatgttcg cgctttttat acacgtttga
    27721 aaccagaaat ccaaatcatt ggtacaggtg ggattcggac aggacaagat gcatttgaac
    27781 atctgctatg tggcgcaagc atgttacaga ttggtacaga gcttcataaa gaagggccgg
    27841 aaattttttc tagaatcata aaagaattaa cgcagattat gtcagaaaaa ggatatacgt
    27901 caattgacga atttaaaggc aaattacgca ccatttcata gcaaagagac gaaggtcatg
    27961 attgatcttc gtcttttttt ataaaaaaca ctcgtctgtt cattcctgtg caagcgtact
    28021 cattgtatgt tagacgaact tgtgggaaaa taacagaggc aaaaaggagg ataatatgaa
    28081 tgatgcaaca gaattagcaa aagagcttaa agaaaaagaa tttagttttc aagaactagt
    28141 tacggatata cagaaaaaaa taaagaagca aaatcatgaa ttgaatgcgt ttgtcgcgct
    28201 tgaaccattc gagagtaatt cccacgagct attgattccc cagtcagaaa aagggccatt
    28261 ggctggtatc ccatttcctt taaaaatgct cggtcaagaa aaaaagggat ggctagctac
    28321 ttcaggatct cgtttatttg aaacacaccg agcttctcat acatctaatt atgtgcggca
    28381 agcagaagcg ataggtctag ttccttttgg acaaaccaat gcgccagagt ttggtttcaa
    28441 aaatattaca gacccagtca tctatggccc agcaagaaac ccttggaacc ttgaatgtac
    28501 accgggcgga tcaagtggag gagctgctgc tgcagtttca tcaggaatcg ttcctttagc
    28561 tggtgctagt gatggcggtg gttctattag aatacccgct tcgttttgcg gattgattgg
    28621 gctgaaacct tcgcgaggga cgatgccagt tggtccatat gcttggagag gatggcaagg
    28681 agctgctatt gatttcggct tgacagtttc tatgagagac acggaggctt tattttatgg
    28741 gatgagaagt atccattccg gtgcgccata tcaagtatcg ccagttgagt ggcaaacaca
    28801 tccaagaaaa aaacggttga agatagcttt ttgtgttgat tcaccgatcc actcacagat
    28861 tagtgaagag gcagtacttg ctgtaaaaaa agctgtagat ttccttggaa aagaagggca
    28921 tgatttgaca gagattcctt acccactaga tggtcgtaaa ctgatcacgt cttattatca
    28981 gatgaatggc gcagaaacag cagcaatgat ccgctcgatt gaaacaggca tccagcgagc
    29041 tgtcagaaaa gaagaacttg aacccatttc ttggactttg ttccaatatg gtcagaagct
    29101 ctctgccgct acttacatcg attctctgca tgtatgggat gaagcagcaa ttgtcatgga
    29161 aaacctacat caagaatacg atctattcct ttcaccaacg actgcattta ccgcccctaa
    29221 aatcagcgaa gatttgcaaa gtgatgcgat aagagcacag atggaacaca tcagtgattg
    29281 ttctgaagta gaaggtttag acgttgtttc ttccatgttt gaggagagct tgaagatcac
    29341 accttataca cagttggcta atctgactgg acaaccagca atcagcttgc ctactcattt
    29401 gacaaaagaa aacatgcctc taggaatcca atttatggct gccagaggaa gagaagattt
    29461 gctatttcaa atcggctatc tatttgaagc aaatcatcag ttccatttac caaatccatg
    29521 gaaatagcag aaacaaggag aagaagaatg aagaaaaaaa gattgtttgc tctaataact
    29581 agtgcctttt ttattttaag cgcttgcggt acagctgccg ctaatcagga agataacagc
    29641 tggagtaatg tagaaaaaaa gaaagaatta gtagtagcga cttctggcac actgtttccc
    29701 gcatcttatt ataatgatca aaatgaatta gttggttatg atgtagattt ggcaaaagag
    29761 gtggctaaac ggttaaatgt caaaatctcc tttaaagaat acaacgtgga tggacaaatc
    29821 acttctgttt caaaaagaga atcagatttt gctgcgaacg attttggtat cacaaaagaa
    29881 agagaaaaaa aattctccct ttcagagact ttcaaatatt catttgacag tatgatcgta
    29941 cgaaaaaaag atgattcagg aatccactca cttgaagatc ttaaagggaa aaaagcagct
    30001 ggcgaaccca atactagcta tatgcgttta gcggaaaaac acggagctaa attagtcaca
    30061 tatgacaatg ccacgaatga tcagtattta agcgatgtag caaatggtcg aacagatgtt
    30121 attctaaatg attattatct gcagaaaatg gccgtatctg ctttaccaga tatccctgta
    30181 aaaatactgg agaacgttta tttcaatgaa aacgaaagtg gttttttatt gaaagaagga
    30241 aatgatgctc tgaaaaagaa aatcgatggc gtattaaaag agatgaaaga agatgggacg
    30301 acaaagaaaa tatctgaaaa atattttcaa actgatgttt cagtcaaacc gaaagaaacg
    30361 atggctgagt cggtgagtga gtgatgtact ttcccctaat tgatttttcc ctcatgtgga
    30421 cttcacttcc tttcgtactg caaggcttgg tatacacatt agggattggc ttcgtgtcgt
    30481 ttcttttagg aaatttggta gggttgcttt tgacagtttt aggtcttttg gattggctgc
    30541 ctctgaatgt atttattcgt ttttatttat cgttctttag aggcattccc gcactagtcc
    30601 tgctgtttct gttatatttc gggttacctt atcaattaag tgccttaacg gcttcagtca
    30661 tctgctttac gattaccagc agtgcattta ttggtgaaat ctatcgagga tcactagcag
    30721 gcgtttcttc aggtcagtgg gacgctggtt tagcttctgg tttttctttc tttggggtat
    30781 tgaaatatat cgttttgccg caagcttttc gaatctcagt accggcactc agtaacgtag
    30841 ctatggatct agtgaaaggt acttcgttag cagcaacaat cacagtgcca gaaatatttc
    30901 aaaaagcaaa gatcataggc ggtcggacat tcgattattt ttctctctat attttagttg
    30961 cactgattta ttgggtcatt tgtatcggga tcgaaaaagt gcaacagtat ttagaaaaac
    31021 gttctatcca tcagtcaatc tgaaaaatag aaatggtgct agcgtggctg gcaccatttc
    31081 tattttttgt ttcttgtata ttctgcctag tattttaaaa ccatttcatg taaaatgtaa
    31141 atcgaaaata tgttcggagg tagaaaacat gaagaccccg ctaaccatcg aaatagaatc
    31201 ctcgttatac caatattgca tcgagcaagg cggcttggtt gtagaagaag tcacgatgcc
    31261 tgatgaccaa ggaattgtag atacgcttag ctgcttgaca aaatttgatg gaagccgaga
    31321 atggcgatgc tatgagctga aagtgacaaa agcagatttt cgctctacag ccaaactgtc
    31381 atttgttgga cattataatt attttgtttt accaagtaaa ctatatgaag aagtaaaaac
    31441 tgaaatccct acaggaatag gtgttttagt gtatcgtccg tacacggttg aagaggagat
    31501 gcctgcctct ggtacatttc tgattgcgaa aaaagcagca aagaaagagc ttgctgtacc
    31561 ggaagaagct ttgacaaacc gcttcatggc ttctttattc agggaagtaa gaaaagcaaa
    31621 gcaaatggag cgaggcgtaa aatattttcc aaaagatcaa ttgtacaaag aattgaaaag
    31681 acgttcagaa aatcaagatc cattttctaa cgaacgatat tatgaacggt ttttagagga
    31741 aatagctagt caggcaatca atgagttgca agaagaagtt atcgcgcttc agcatgatta
    31801 tgaatatttg aggcaacaac agcagatccg tcggttgcct acagagccat tggagtgaaa
    31861 aatatgtact atccttattt aagaggaaaa caatttgacc tattagcatt aaaagaagca
    31921 ctgtcgcgag gattgctctc caataaaatc caaccagtga tcgaaccagt acgtgattcc
    31981 gctacgctta aaaatgtgat cgaattattt caaaaaaagc accatccaat cgctgtgatc
    32041 caaaatcccc aagtaggaca attcaaatta ttcgatcagc atgtgcacag ttggacagtc
    32101 aaagaaaata gctctgtcgt ccctgcacag atcttaacgc cagaaaatct cagtgaagta
    32161 ctggattcac ctccagcgtt tcttgttttc gatggacagc actacccaaa agatacagag
    32221 gtgtggaaac agttggcagg agttgattcg aaatttttga taccagatac tagtcgcttt
    32281 cgcatctggc tgcccgaaaa caaaattgtg atccgtgact cttttcaaac gagaaagcat
    32341 gttgaaagtt atgcagataa aacagatgac ttttttagtg atgactatct ttttttccac
    32401 gcagacggat atattggatt ttctgatttc acgatcgaag gtagccgtta tttcgataaa
    32461 gggttcccta gccgagcgct tgctatccat ctaacgtata ttgatgctta cggcaatata
    32521 cgcgtgaaac attttgtctc tgacagtaac gactctgcta aagaccaagc attgaagttt
    32581 cttgaagcag gagataaaat gaaaaaatgg atcatgcgtc accatcatca actcttgatt
    32641 acttcaggaa tgattgaatt attggctctt taccagcaac aaaaattccc tggactggga
    32701 gtgttgaaaa agtggtcact tatgcatcat ttggaactta ttagtcacct gctagatcat
    32761 ccaaaagatt ggcttaaata ttattcaaaa gttcaggaac tatatgaagt gatccaatga
    32821 ttagataatg taaatgaaaa aggaatagaa aagaggaaac tggatgtata ttcggcaaac
    32881 aaggaaagaa gaagtagaag aagtggtaga aatcattaat gccgcagcgg atttcattgc
    32941 ttcgcaaggc tctcctcaat ggcaaaacgg gcagaaacca acaaaagaaa cgattttgaa
    33001 cgatattgaa agaaaagaaa gctatgtatt aatagtggaa gatcaaattg ctggaacagc
    33061 tgcattagtc tcaggcgtgg atcccgttta cacaaaaata gatggtagtt ggaaagaatc
    33121 aactggtcct tatttatcga ttcatcgtgt cgctttagca gaaagtactc gaggaaaaaa
    33181 actagcaaaa ccgttcttag aacatttgtt gacgattgca gccagcaaaa atatccaaga
    33241 tatccgtatc gatacttatc cagctaatga accgatggaa aagaccatct attctgctgg
    33301 attcacttat caagggatga ttgaatttcc ttttgaacac ggcgaaagaa aagcatatca
    33361 aataatcatc aattgactat aaaatcatct gagcaaagat aaagacatta acactactga
    33421 aaaaaacaat catatgatag ccaagaggtt gtaacagaag tggccagctt caaaaaacaa
    33481 gaaagaattt ccgaaaatgc ttctcaaatt tttgtggaat tttagcgtat tttacgaaat
    33541 agctgctttc tgaaactccc ttcatcgaga ggtcgtgaca tagcttttgt cacgatctct
    33601 cggcttatcc tacgagtatt attcgataca tttatatcaa taatcctttt tttattttat
    33661 ctgcagcttc ttggaacgct ccatcgtttg acacgactaa aagtgagggg atagctttca
    33721 aacgtttcaa ctgtgctaaa tcttctacat aaaccgccag tctggctgaa atctgttcag
    33781 atgaatctcc acgttttttc aggcgcgatt gcaatgtttc tttagagatc gtaataaaga
    33841 taggacggac taccgtcccg aaatactcat ataaatgcca aaaaccattt gctgtcaaaa
    33901 cggcgtaaca atttcctact gtcagtttct ttttaatttc tgctttactg gaaccatatt
    33961 tatgttgagc atattggtcc cactctgcaa actcatttcc cttgatcatc tgattgaatg
    34021 tattgtcaga aacaaaataa taatcctctt gatctttttc cccaggtctt ggtgatcgat
    34081 tcgtgtaagt aatgatcttt tgttccggct gaaaaatagc ttctgcgagt gaagtttttc
    34141 cagaaccaga aggaccgata aatacatagc aataattcat tgtcatttct cctttgatga
    34201 ttgaacaagt gaaaaagctt tggaaaatat ttccaaagct tttaaaagta actttgcttt
    34261 tttgtatttt ataccagcaa gccagtcaca atagcactta aaaagctgac taaagtcgct
    34321 gttagcaaaa ttttcaatcc gtgttttgcg acaagatttc ctttttcttc atttaatccc
    34381 ttcatcgcac cagaaatgat cccgatagaa gagaagttgg caaatgaaac gaggaagaca
    34441 gatataattg ctgttgtacg ctcagtaaaa tggaaattac catttgctaa ttctgtcata
    34501 gcaacaaatt catttgtaac cagtttagtc gccatgatac taccggcatc cactgcttct
    34561 ttccatggga ttccgctgat gaaggcaaga ggggcaaaga tgtaacctag gatctcttgg
    34621 aaagtgatgc cgaatatccc gtggaagata gcattgatca tggcaatcaa agcaacaaaa
    34681 ccgataagca tagcagcaac cgtgatcgcc acatggaaac catcaagaat gtattctccc
    34741 aacatttgga aaaatgtctg ttctttgttt tcttcaatga tcagctcatc ttctttttct
    34801 tctaatacat agggatttac aattgaagcc agaatataac cgccaaataa gttcaaaaca
    34861 agggcagtga tcacatattt agaatcgatc agtgccatat aagatccgac gatcgacata
    34921 gaaactgtag acatagccga tacactcatg gtgaacaaac gtttctcaga taggaagggt
    34981 aattcctttt ttatggaaat aaaaacttcc gattgtccta aaatagcaga agctactcca
    35041 ttataagatt ccaatttgcc catcccgttg attttactta atcctagacc aacagctttc
    35101 ataaataatg gaagaatctt gatatagcgt agaataccga taatagcaga aataaataca
    35161 attggcatca atacggaaag aaagaaaggt gcacttcctt tatttgctac accggcaaaa
    35221 acaaagtcaa caccttgccc agcaaaagca agaagatgat caaacatttt tgccaataca
    35281 gaaacaaccg ctgtaccaaa agttgtacgt aataatacga aaccaagaac aagctgtaaa
    35341 acgaacatca caattagtgg tttcaatttg attgcttttt tgttactgct gatcaaaaaa
    35401 gcaagcccta atgtgacaaa taaaccaata atacctaata aataactcaa ataatcactc
    35461 ctattccaaa ttccgtttta ttttacctgt tttgcaaata aaatactaat ctttagtgaa
    35521 attttcatta cttttttaga gtgaaacgca ttcattttcc attagaaaat aaagcgaaca
    35581 aaataaaagg tttaaaaagt gtaacgtctt agtaaagtct ataaaaaaac gaaactatcg
    35641 attaagctaa tagtttcgtt ttcaacattt ataagtaaac tttttctatt ggtaatatag
    35701 attttcggaa gggtagacag gtgcgcaggt aatatcgatt cctagttttt tcaatgtttg
    35761 ttcatcattt ttattgacca tcacagtaga gtgggcttgt gctccctcaa gttcagctag
    35821 tttatcataa gcaacttgag cgattggatt cgttactgca ctgattgata aagcgatcaa
    35881 gacttcattg atgcttagtg catccaaaga ggaatgaagt gtctttgatt tcaatccttg
    35941 tattgtttca agaactaatg gtgacaataa aggaatgtca tctgcgatat gggctaaatg
    36001 ttttactgca tttaagataa ctgccgctga cgcatccatc aatgaacttg tacgcccggt
    36061 aatgatgact tcatctggta attcgattgc aatcacagca gaaggatctt ttgtaggact
    36121 ttgcgcttga atcttatctg catagtcatg ggcagggact accacgtttc ggtcttcagg
    36181 acgtaaaccg acttcttcca taatcagttt gattcgatta actgcttctt cgtcgatcaa
    36241 tccttttttg aagtcgcatt ctgtttggaa ataacgacgg atgatttctt gtttagaggc
    36301 ttcttggaca acggtatcat ccacgatccc aaatcctaca cgattcacac ccatgtcagt
    36361 aggagattga taaacagatt ctttaccagt aattttttca ataatacgtt tgattacagg
    36421 aaatgtctca acatcccgat tatagttcac agctacttta ttgtaggcat caaagtggaa
    36481 ggaatcgatc atattgacat cttttagatc gactgtggct gcttcataag caatgttcag
    36541 cggatgtttc aacggaacat tccatactgg gaaagtttcg aacttggagt aaccagctgc
    36601 atgtcctttt tggctttcat gatacagttg gttcaagcaa gtagcgagct ttccacttcc
    36661 tgggccagga gctgtcacta caacgattgg tttagttgtt tcaatatact cattttttcc
    36721 aaaaccatct tctgagacga ttttttctac gttgactgga tagtcttcga tttctgagtg
    36781 tttatagacc ttgatgtttc gtctttctag tttattgata aagactttcg tggcaggctg
    36841 tccactatag cgagtgataa cgacactgtt gattaataag ccataaccac gtaattcatc
    36901 gattaaccgc aagatatcca tatcataagt aatcccataa tcaccacgga tcttattacg
    36961 ttcaatatct ccagcataga cgcaaatcag tatttcagct tgatctttca atttttgcag
    37021 caatttgatt ttcgcatctt cttcaaatcc tggaagtaca cgtttcgcat gcttgtcgtc
    37081 aactaacttc ccaccaaatt ctaaatataa tttgtcatag tggttcactc gttccaaaat
    37141 atacgctgac tgctcttcaa tatatttttc tgaatcaaaa ccaatttttt tcactaggtt
    37201 ccctccttaa gtactaaagc attttttcat ttttttgagg attcgtcaac tggaagagcg
    37261 aaattcctca aaaaaacaaa gaaaatggtt taaaccaact tgtctagata gttattcatt
    37321 ggtatgatag tttttgataa ggaaggtgct acatgaaaaa aagacagaaa aagaaaaacg
    37381 catataaaca ctatatccgt tcgattttta ccggttatga aagaatgctt gaagatcccg
    37441 aattggaaca attgacgttt acttatctaa acgaagaaac gcagctaact cgtgatgagc
    37501 atcagcgcat tcatttcaca acaagagatc tgcctagtaa ataaaaaata agataaaggt
    37561 catcggattc gattctgtcc tatcagatgg aaagactagt tgatcgaaaa aaaggctgta
    37621 ccaaattttg gtgcagcctg ttttatggag cattgcccgc tcttttttat aacaattttt
    37681 tacagaaaat ggtactattg aagtattaat aagtgaaaaa cagatgagta agaggaggca
    37741 agtagtatga aagagccaga tacaaatgca aattatgagc cagacgaact agaggagacg
    37801 aacgcggatc aggatacagg acaagaatcg tcttcttttt acgatatcaa agaaaaagca
    37861 agcatgaatc tttcccaatt attagaagac ttacaggctt ttgaaaaagc tgtccgcgaa
    37921 gaagatatcc ctgagatcta ccgtttatac aatggccgat tgaatgaaga attaaaaaga
    37981 agctcaaatg aaaatcacga gatcgatcaa ttgctgatgc gtaagatcca tgatcgtttt
    38041 ttacaggaat ttccttttat ggaacaagta gaaaacatct cgccaacgat gagctattac
    38101 aaaatcggca cttattacca tgatcggccc acggtcggta ttgatgcaag tctgccagaa
    38161 atttttgttt tgcctaagat cgatgaagag tgggagaaat attcccaacc ggagtcaacg
    38221 gactatgaca aaaaaatcaa tgagctagac gcaaaggtga tcactgctca gacagaaatt
    38281 gaacgtttag atgaacaaat aaaagaaatc aatcgacaaa tgactgattt gaacgacaat
    38341 aaaggattct tgaatcgtaa aaaaatcgag gaagaaattc aagaattaga gaagaagaag
    38401 caagtactat ctaatgaaaa attaggctgg cttccttata ttgagacgcc tgaaacaatc
    38461 cagcagcaaa aagaagcatt gaagcaagaa gcaagagcag accagcttcg tgcagccatc
    38521 gtagaaaaag aacaaaggca aatcagacgc tatttcggta gcaaagaggg attcggtcaa
    38581 gcaatccatg aattcttgat gaattatctt ggcaatgaga atcctaataa tcaatctaat
    38641 gaaggaggtt ccgagtatga atgaacacga tgaagcagaa tggacaaaaa atgaagaaca
    38701 aacagaagat catgaagaaa cgaacacttc attggaagaa caaacaagta atcctctgga
    38761 tgacacagaa gaaatcccta tgctagagga aacaaaaata catgaaaaag aaaaagtaac
    38821 tccgacgaat acgaatactg cagaaaacac ccatgcttac gaaataactg aaaatcccgg
    38881 gtatttagaa ggaaaagagc aagatcatca agatatcgtc agtttgattg aaacagcgga
    38941 agcagaatta gcggatttac gtatgagaaa agatttgatc gaatcagatt ttccacaatt
    39001 attagaatca tatgatcgtt ttatattgaa tgaagaacca atctccacga tcggaaagac
    39061 aagcctgatc gaatacttca cgtatgaatt actgaaaccg ttgaatgata ttggtctgga
    39121 acggtcaaat tcagcttatg acacatggaa aacaagacat ttttcgatca attatacgtt
    39181 gaatggacaa aacgaattag tcttttcctt tgtattaccg accatcgatc aacgatacca
    39241 agtggaatcg atgagtctcc taaacgtatc accagagaca atggaaatca atgtccaaga
    39301 tgaccgggtg ctttctttga tccgacactg gtcagtggat cgagtattct ctgcagggca
    39361 gatcacgata ttcaatcaca aattgaatca attattagcc catgcaagaa cacttggttt
    39421 taccgttaat cagacattac tagacaatac gaagccactt cgtttgaatc ttcagagcga
    39481 atttgaattg acgaatgaag tattggatga tatttttatc gtggcaatga aaaatccatc
    39541 ctacgatatg gaaaagatca acgaaactac ttatcaagta cgattagata aaggacagtc
    39601 tttaacgata acaacaaacg aaaaagatca aacagtcttg tcgatctcat ctggagacta
    39661 cccacgatct gtcattgatt tctttatcaa ttacgaattc ttggtcccat taatggtgag
    39721 aaagtcctga ttggataagt tggattacca gatgtcattc agataattct gttccaaagg
    39781 acttgcggca gttatccaga ataattgtca caagtctttt ctgtatgtac taaatggacg
    39841 tgaataactt gctgatgaag gagggatttc attaggaatg tccacaaata aaatagcaca
    39901 gcttagctta ttgtctgctg cttgtgtagc aggtaggatc gcttttcaat ttattccgaa
    39961 tttccagcca atgactgcta tttttttatt tatagtactt tacttaagct taaaagatgc
    40021 gttaattgtc atgagtcttt ctattgcgat cagcagtttt tattttggtg ttggaccatg
    40081 ggtcatcggc caatggatca gctatactgt tgttctgagt ttgttttcaa tcgtctgctt
    40141 gagaaaaaca gtgcaaagga atctatggtt aaagggagtc tgtttttttc tggcgggcat
    40201 ggtttacgga ataggtatga ccgtttttga tacgctgtta tatcgtttgc ctcaaccttg
    40261 gatctattac cttcaagggg tgtcgtttga tttgatgcac agtataggca atgttgtgtt
    40321 ctttcttgtt tttctgccag tcgtcaaacg tttttacaat cattcaggag gaaaaaatga
    40381 aaaaaataat ttatagtttg cttgcaatga gtgtcagtat actcattttg acaagttgca
    40441 gtacaaccta tacacaatcg gcttccaacc aaaaggagga agtaaaaaca tcgcaaaaag
    40501 caacaatcac gttacaagaa aatggtcaaa acttttcgga aaaagaagtg gtcttcaaaa
    40561 aaggcgatga tttactgagt attttgaaac gaaattttga agtcaaagaa gataacggct
    40621 tcatcacttc gcttgaaggg cactcacagg atgagaaaaa tcaactctat tggatgttta
    40681 ctgtggacgg gaaaagtgct actactggtg ccaaagagat caaattgaat gatggacaat
    40741 cggtcatttt caatttgtct aaactataag tttcataaaa aactgttaaa gggcgaatat
    40801 tgccataatt cagtgagttc agttgatgaa agaaggaaaa taacatggaa aattttaaaa
    40861 aaagcggaat gttttccgta attgctgctc taggggctaa tattctagtt gctatcagca
    40921 aatttgtcgg ctatgcaatc agtggcagtg ccgccatgct aaacgaaagc atccacagta
    40981 tcgttgattg cagcaatcag attttgctgt tattcggtga taaacaagcc aataaaggac
    41041 agagcgagtt gcatcaattt ggtgaaggac gagcaaaata ctttttcagt acaatcgtcg
    41101 caatgatgct tttcttcggc ggtggggcac ttggggtgat ggaagctttt gaaaagttga
    41161 cgcatccatc ccatgaagtg ggtaatccga tcattgttat agcaatactg ttatttggtt
    41221 tggtaatcga aggaagttcg ttacgcgtgg caatgaaaga aatcaaagaa ttgaatactg
    41281 aaaaactttc cacgatgcgc tttttgcgcg aaagtcgaca cagtgaaata ctgattattt
    41341 ttacggaaga cttgtgtgct gtaatcggtt tggtcttggc tttagcagga acaatattga
    41401 cttatgcaac cgggattgct gcatttgatg cgatcagcgg attgctgatc ggtttcttgc
    41461 tgatgggagc cgccattttc ctagcaaaag aattttatag tctgatcatc ggtgaaagcg
    41521 tgacagcaag cgatttatca aaaatcaagt tagcttttga acgtcctgag atcagtcggc
    41581 tgatcgatat aaaaacagtt catttaagtc caacggagat tttagttgca gcaaaagcag
    41641 atatcgttgg taacaaagag aatgaagctt actcggtcat caatgatatt gaaaaaaata
    41701 tgcgtcagtc tcttcctgac aagaagatgt atatatacat tgaaacagat aaatatgacc
    41761 caaattattc tcgtaaataa aacgtttatt catgaattga agcaaaaatg agaaaaatat
    41821 aatcttgttt ttaaataaaa cggctacaat ttagcgaatt tatgttacaa tgagtccgct
    41881 gtttatttgt tgtaattaaa ggagatattt taatgaacaa aaagaaaagt gcgccatggc
    41941 ttcaagcttt gcatgcagtg atgccacttt gtataagcta tataccagta ggattagctt
    42001 gcggagtatt gttgcaaaaa gttggatttg atcctctctt atcaggactg ttatcgattc
    42061 tggtcttttc cggtggcgcg cagtttttag ttgcatctat gcttacgacg caagcatcat
    42121 ttgcaacgac attattgatg gttttctttt tagaattacg ctatacatta ttaggagcaa
    42181 gtcttgccgg ttttatgaaa aaagaaaagc ggacgttttt ggctgtcttt tctcaatcac
    42241 tgaatgatga aaactatgcg gtgaactact taaagttttc aactgaccct tcctggaata
    42301 aaagaaaggc tttatatgtc aattggttct caatgactgc atgggccggt agcaatatga
    42361 tcggtaattt tttcggctcg gtgattcgag tagatgctga ccttgtccat tttgctttga
    42421 cggccatgtt cattttcatg tttatcatgc agatgaaaag cgcactactg atctttacag
    42481 gtttattctc aggcgtatta ggggtcgtat tcatggtatt attccaaaat actttcggat
    42541 tgattgcagc aacagtcatt gcttcatttg ccggatttat gctggagaag gcattcaaaa
    42601 aagaaaaagc taagaaacta agagaccgcg gtaaagatgt caatgagccg ctcttcaact
    42661 tcccggaaca ggaggccaat caccatgact aaactatatt tgctactttt agttgcttgt
    42721 ctgttcatcg tggcatatat cccgcgcttg ttcccgatgc tttattttac tcatcgaaaa
    42781 gtgccatcct ggttcagtga ctggatgaaa tatgtaccgg tggcattatt tgcggcgtta
    42841 gcttttaaag atgttttcat tactcatgaa catctggata ttgcttggaa tatcaaaata
    42901 gctgcaatga ttctagtagc aggcgtggct tacaaaacac gttcgatggc gttgtcagtt
    42961 ttgacaggac ttgcgtctgt ctttttgctg tctatgcttt aaactgtttt attttattaa
    43021 aaacagagat tgcgacataa gttgttcaaa ctgatctatc cgaactgcat ttgcaacagt
    43081 caattctgga tgcaagttta ttcgtaggga taaaaaagat tagtgttggc ttatgatgca
    43141 agctcttttt tattttagga attagagagg gatttgtcct tctatgattt tttgctataa
    43201 tagggaagat gtttatttta tgaaagaata gttgagggaa tttaaatgaa taaaaaattg
    43261 atgcaaggaa cattttggct aacctttgct aatcttctat gtaaagtttt aggggtagtc
    43321 tatttgattc cctggctaag tatgatgggg aacaatcaag atggtatgct tgctacgaca
    43381 ttgtataatg ttggctatct tccttatgga ttgttcctga tgcttggtac agtcggattt
    43441 ccaaatgcga ttgcaaaaaa agtagctgta gccacaaaag aaggagataa cgctgcttgt
    43501 cggctgattt ttagaagtac gatcaatatc atgtttgtca tcggtatcgc ctctgctgca
    43561 ctgatgtatt tatttgctcc tttactagcc ggaatcagtc cgattgctaa cgttaataat
    43621 gggatactag ctatcagaag tttatgccca tctttgattg ctatcccaat tcttagtgca
    43681 atgagaggat atttccaagg aaaaaatgat ctgcggcctt atggaacttc tttgattatc
    43741 gaacaggctg tgcgagtgat cgttatcttg gctggtactt attacttgcg cgtattgact
    43801 gacggaacca tattagaagc tgtattgatc agtacagtcg cttctttctt cggtgggtta
    43861 gctgcgatta tccatatgta tatcgtcgga cgcagaaaag acttcttcga acttaaagat
    43921 tttttgattt ccagccgtta tttcgaaaga gaaaaccgat ctgcctctgt ctctatcatt
    43981 cgggaaacac taccgtttat ttttgtcggc tcagtcatta ctatcgttca aatgatcgac
    44041 caagtaacga tgaaaccact gcttcacttt ttccgtccag agatcgcaga tcagcaactg
    44101 gaattcttat tcagccgtgc ttctgtcaat ccaaataaat tgacattgat cctgatctcc
    44161 atggtaggaa cagtagctat aagcagcttg ccaatattaa gcacgatgaa gaaaaaagat
    44221 cggatacaaa tcgaaaaaac agtaggagat agtttttcga ttgcgttatt gattcttctt
    44281 ccttcattga ctggaatgtc tttattagct ggaccactat acacattgtt ttttggctat
    44341 gatcctgaaa gtgtcggata tttccaaatg gctttgctag cttctttgtt tttctcttta
    44401 ttcacgatcc tatctacgat gcttcaatct ttgaatcacc atcgttttgc gatccgatta
    44461 actgtagaag caattatcct gaaagtcatc ttccaagtaa tcggattagg attagttggc
    44521 ggatacggga tgagcttatc aaatggctta gcattcggta ttgtctttgt tcgcggctat
    44581 cactttatgt gcaaagaata ccgaatagca cctttagcaa agatcagcaa ttttttctta
    44641 aaaactttcc gctccaccct gattatgctt gcagtatgtt ttgccgtttt ctttttgctg
    44701 aatcagcgat tgtcaatgga atcaaaaagc tatgcaatga tttattgtgt ggctgtagga
    44761 agtattggcg gcttagtatt tttattttct caattcggaa aaaatgggtt tcgaatgttg
    44821 aaaaatgtta aacatcatag cagaagcaaa gaataggtta actaatcgtt ttttgctgtc
    44881 acttgaaaaa cggcaactcg tatgattacg cttgtcgttt ttctattttc caattttagt
    44941 ttcatatcta atcttactta tgatatagtt ataaggtctg gaaaaattct ttgaaacgag
    45001 gaaattaaac acatgaaact tgcagtagtt acagatagtt cggcatatct gccggaacgt
    45061 atcaagaacc atcccgactt attcgttatt ccaatccctt tgattatgga tgggaaaatt
    45121 tataacgaag gaatcgatat cgaagcggat gaatattatg gacttttaaa aaacagtaaa
    45181 gattttccta ctacttcaca acctgtcgta ggggaagttt tgggtttata tgaggaattg
    45241 aaagagaaag ggtatgacac gattttaagt atccatcttt cttcagggat ttctggcttt
    45301 gtcaacacat tatttgcgat gaaagatgac atcagcggag taacggtcat tccttatgac
    45361 tctaagatca ctagtatgcc gatgggacac atggtagaag ctgccttaga cttaaatgat
    45421 gaaggtcagt cccttgatga aatacttgca catatcgatc gaatccgaga taatacctat
    45481 gcttatctga ttgtagatga tttgaacaat ttagtacgag gaggacgttt gacaaatggt
    45541 gcagcgctga ttggcagctt attaaaaatc aaaccgatcc tgacattttc tgaagggaaa
    45601 attgttttat tcgaaaaaat ccgttcaagt aaaaaagcat ttgctcgagc tgaagaaatt
    45661 attggtagaa gaaataacga aatacaaccg ccagtcaaac tttacgtgat acatgcaaat
    45721 aatttagaag tagcgattgc ggagaaagag aaattgcaga aaaaatatcc aaatgcagaa
    45781 atcgaaattg gtcatttcgg accagtcatt ggtacacatt taggtgaaaa agccatcggc
    45841 attgccattt cagcgcaata attcctttta ttcaaaaaac ataccaaaaa tat
//
LOCUS       DAYYEF010000017        45447 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000017 DAYYEF010000000
VERSION     DAYYEF010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45447
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.017"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            274..1143
                     /locus_tag="ACHA1B_001112"
     CDS             274..1143
                     /locus_tag="ACHA1B_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM8701891.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1352..2377
                     /locus_tag="ACHA1B_001113"
     CDS             1352..2377
                     /locus_tag="ACHA1B_001113"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFM8701892.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2416..3366
                     /gene="manA"
                     /locus_tag="ACHA1B_001114"
     CDS             2416..3366
                     /gene="manA"
                     /locus_tag="ACHA1B_001114"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HFM8701893.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3460..5163
                     /locus_tag="ACHA1B_001115"
     CDS             3460..5163
                     /locus_tag="ACHA1B_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFM8701894.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5165..7198
                     /locus_tag="ACHA1B_001116"
     CDS             5165..7198
                     /locus_tag="ACHA1B_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HFM8701895.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7209..7649
                     /locus_tag="ACHA1B_001117"
     CDS             7209..7649
                     /locus_tag="ACHA1B_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM8701896.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7849..8976)
                     /locus_tag="ACHA1B_001118"
     CDS             complement(7849..8976)
                     /locus_tag="ACHA1B_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8701897.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8979..9656)
                     /locus_tag="ACHA1B_001119"
     CDS             complement(8979..9656)
                     /locus_tag="ACHA1B_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM8701898.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9920..11686
                     /locus_tag="ACHA1B_001120"
     CDS             9920..11686
                     /locus_tag="ACHA1B_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol-specific transporter subunit IIBC"
                     /protein_id="HFM8701899.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11701..12138
                     /locus_tag="ACHA1B_001121"
     CDS             11701..12138
                     /locus_tag="ACHA1B_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM8701900.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12151..13302
                     /locus_tag="ACHA1B_001122"
     CDS             12151..13302
                     /locus_tag="ACHA1B_001122"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HFM8701901.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13364..14062)
                     /locus_tag="ACHA1B_001123"
     CDS             complement(13364..14062)
                     /locus_tag="ACHA1B_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HFM8701902.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14055..15407)
                     /locus_tag="ACHA1B_001124"
     CDS             complement(14055..15407)
                     /locus_tag="ACHA1B_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurT ligase domain-containing protein"
                     /protein_id="HFM8701903.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15630..17030)
                     /locus_tag="ACHA1B_001125"
     CDS             complement(15630..17030)
                     /locus_tag="ACHA1B_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015079 - potassium ion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HFM8701904.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17191..17928
                     /locus_tag="ACHA1B_001126"
     CDS             17191..17928
                     /locus_tag="ACHA1B_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HFM8701905.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18053..18532
                     /locus_tag="ACHA1B_001127"
     CDS             18053..18532
                     /locus_tag="ACHA1B_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HFM8701906.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18529..19296
                     /locus_tag="ACHA1B_001128"
     CDS             18529..19296
                     /locus_tag="ACHA1B_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6681 family protein"
                     /protein_id="HFM8701907.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19526..20095
                     /gene="lepB"
                     /locus_tag="ACHA1B_001129"
     CDS             19526..20095
                     /gene="lepB"
                     /locus_tag="ACHA1B_001129"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006465 - signal peptide processing
                     [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HFM8701908.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20199..20801)
                     /locus_tag="ACHA1B_001130"
     CDS             complement(20199..20801)
                     /locus_tag="ACHA1B_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFM8701909.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20907..21137
                     /locus_tag="ACHA1B_001131"
     CDS             20907..21137
                     /locus_tag="ACHA1B_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701910.1"
                     /translation="MPISFVKDREEKGKCVREILLDLPEWFGLPESTEKYIEESSKLP
                     LWCEKRKEEYLGFITLSQTSEDTAEIYSIVWE"
     gene            21128..21376
                     /locus_tag="ACHA1B_001132"
     CDS             21128..21376
                     /locus_tag="ACHA1B_001132"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: protein motif:HMM:NF025054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8701911.1"
                     /translation="MGIKKDYHHQGLGTKLFKEAEGYAAKHYKYLQVKTVDEGHYSIY
                     DQTICFYESLGFSRLEVFPNLWDEWNPCLVLVKKLEQK"
     gene            21482..22066
                     /locus_tag="ACHA1B_001133"
     CDS             21482..22066
                     /locus_tag="ACHA1B_001133"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004797 - thymidine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HFM8701912.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22069..23142
                     /gene="prfA"
                     /locus_tag="ACHA1B_001134"
     CDS             22069..23142
                     /gene="prfA"
                     /locus_tag="ACHA1B_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003747 - translation release factor
                     activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HFM8701913.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23135..23974
                     /gene="prmC"
                     /locus_tag="ACHA1B_001135"
     CDS             23135..23974
                     /gene="prmC"
                     /locus_tag="ACHA1B_001135"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA];
                     GO_process: GO:0018364 - peptidyl-glutamine methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HFM8701914.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23967..24146
                     /locus_tag="ACHA1B_001136"
     CDS             23967..24146
                     /locus_tag="ACHA1B_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701915.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24168..25193
                     /locus_tag="ACHA1B_001137"
     CDS             24168..25193
                     /locus_tag="ACHA1B_001137"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003725 - double-stranded RNA binding
                     [Evidence IEA];
                     GO_function: GO:0061710 - L-threonylcarbamoyladenylate
                     synthase [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HFM8701916.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25368..26612
                     /gene="glyA"
                     /locus_tag="ACHA1B_001138"
     CDS             25368..26612
                     /gene="glyA"
                     /locus_tag="ACHA1B_001138"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0070905 - serine binding [Evidence IEA];
                     GO_process: GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HFM8701917.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26765..27712
                     /locus_tag="ACHA1B_001139"
     CDS             26765..27712
                     /locus_tag="ACHA1B_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase fold domain-containing
                     protein"
                     /protein_id="HFM8701918.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27846..28475
                     /gene="upp"
                     /locus_tag="ACHA1B_001140"
     CDS             27846..28475
                     /gene="upp"
                     /locus_tag="ACHA1B_001140"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004845 - uracil phosphoribosyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HFM8701919.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28614..28856)
                     /locus_tag="ACHA1B_001141"
     CDS             complement(28614..28856)
                     /locus_tag="ACHA1B_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701920.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28977..29049
                     /locus_tag="ACHA1B_001142"
     tRNA            28977..29049
                     /locus_tag="ACHA1B_001142"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29010..29012,aa:Thr,seq:cgt)
     gene            complement(29168..29806)
                     /locus_tag="ACHA1B_001143"
     CDS             complement(29168..29806)
                     /locus_tag="ACHA1B_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0070007 - glutamic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family glutamic-type intramembrane
                     protease"
                     /protein_id="HFM8701921.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(29929..30561)
                     /locus_tag="ACHA1B_001144"
     CDS             complement(29929..30561)
                     /locus_tag="ACHA1B_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HFM8701922.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            30912..31211
                     /locus_tag="ACHA1B_001145"
     CDS             30912..31211
                     /locus_tag="ACHA1B_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0030153 - bacteriocin immunity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFM8701923.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            31706..33871
                     /gene="acm"
                     /locus_tag="ACHA1B_001146"
     CDS             31706..33871
                     /gene="acm"
                     /locus_tag="ACHA1B_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HFM8701924.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(34143..34628)
                     /locus_tag="ACHA1B_001147"
     CDS             complement(34143..34628)
                     /locus_tag="ACHA1B_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HFM8701925.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    34718..35063
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            35108..35749
                     /locus_tag="ACHA1B_001148"
     CDS             35108..35749
                     /locus_tag="ACHA1B_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFM8701926.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            35768..36403
                     /locus_tag="ACHA1B_001149"
     CDS             35768..36403
                     /locus_tag="ACHA1B_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFM8701927.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            36421..37236
                     /locus_tag="ACHA1B_001150"
     CDS             36421..37236
                     /locus_tag="ACHA1B_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM8701928.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            37555..38991
                     /locus_tag="ACHA1B_001151"
     CDS             37555..38991
                     /locus_tag="ACHA1B_001151"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFM8701929.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            39180..41627
                     /locus_tag="ACHA1B_001152"
     CDS             39180..41627
                     /locus_tag="ACHA1B_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HFM8701930.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            41857..42924
                     /gene="rlmN"
                     /locus_tag="ACHA1B_001153"
     CDS             41857..42924
                     /gene="rlmN"
                     /locus_tag="ACHA1B_001153"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA];
                     GO_function: GO:0016433 - rRNA (adenine) methyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0030488 - tRNA methylation [Evidence IEA];
                     GO_process: GO:0070475 - rRNA base methylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HFM8701931.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            42914..43120
                     /locus_tag="ACHA1B_001154"
     CDS             42914..43120
                     /locus_tag="ACHA1B_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701932.1"
                     /translation="MPNNRILLVFSITIKGAVFLIKELFNLNKRKDSIAKAIKLFLTR
                     KTLIKQRNVLNLMTACLMGVLAII"
     gene            complement(43117..44220)
                     /locus_tag="ACHA1B_001155"
     CDS             complement(43117..44220)
                     /locus_tag="ACHA1B_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFM8701933.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            44773..45321
                     /gene="aac(6')"
                     /locus_tag="ACHA1B_001156"
     CDS             44773..45321
                     /gene="aac(6')"
                     /locus_tag="ACHA1B_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFM8701934.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT        15542 a         7792 c         9277 g        12836 t
ORIGIN      
        1 cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa
       61 taggaggagc tatttttgtt tggctgttct tattacttga tgcagaacag ctttttcaca
      121 acctcttttt ataagagttt ttactcatta atttacaaaa aacaagcaaa atgcgaattt
      181 tctcacattt tttttaacaa aatcaaagtt attgcttgaa agaagaagaa tccatcgtta
      241 aaataaagct tgacgtagag gggagcaaga aatatgaaag attttcaatt gggggctgcc
      301 acctatttaa aaagtgtagc cattcgggtg aaagaccgag ataaaatgat tgatttttac
      361 aagaacgttg ttggctttga tttgaaaaga gaagaaaacg aattagccat tttaggaaca
      421 gaagaagctg gaagtgaaat gttgctgctg gaagaaagtc ctagagcgaa tgatcacatg
      481 ggggtgatca aaaagctgaa ccgtttttca ttgattatcc ctagcacaga agaaatggca
      541 gatatccttt gtcgtatccg taaaatgaat tatccaatca aagaagcttt agaagatcat
      601 ggacgtatgg ggattttgct cgtagaccca gaagagaatg aattggaaat ttaccatgaa
      661 gagaataaga acgaccaaag agaaattcca gaaacaatgg atcaagaagc attattaaga
      721 aaatctgaag aaaaattcag taaactatca acaggttctt attttgaaaa aatccattta
      781 aatgttacta acttaacaaa agaacgccaa tttcttaatc atgtacttgg tttgaaggta
      841 cataatgaag aagagggcat ccatgtattg aatgaaggag atttccatgt tggtttgaca
      901 gaagctagcg gaggcgcaat tgatttgcct acagatgaag tgattggact tgattttctg
      961 aaattcatga tcgatactga aagcatggaa ggactgattg ctcacttgca gcaactatca
     1021 gttgatttct tcttagacaa aaagcacaca gtactcacaa tctatgatgc tataggaatc
     1081 gaatggtggt tcgtcagtga gccaaaagaa aagaataaaa ctgacattcg atgcgacgct
     1141 taactttttc tttcttaacg attgtcgcat gtctcgtcat tttatgaacg gtcatactat
     1201 cgcttattct agagatagaa agagaaaata gtataccggg ggaaactgcg cggtttttcg
     1261 cgcagttttt ttgtgtaaaa aaggttgatt cctcatagat taagctttaa gcttggactg
     1321 taagaatctg atagaaaagc aggagaaaaa gatgtatcca cacacgaaac agcttatttt
     1381 gaaaaagatg gaagaaggat tttatccagg tgtagcagtc gccttcataa aagaaaatca
     1441 agtagaaaca tttacagccg gctttgccca agtcgttcct gaaaagcagc tgatgacaga
     1501 agatctgttg tttgatgcag cctcactgac gaaagtcgtt gcaaccactt cattagtttt
     1561 acgtctatta gaagatggaa agatagaact cgatcaaccg cttcataaat atcttcctga
     1621 atttgaaaat cagacaatca ctttgcgtca tttactgaca catacttctg atatcaaaac
     1681 atggatacca aacagagata agctatctca ggaagaattg atcgccgctt atttgaagct
     1741 agaaccaggt gagcaactag gaaaagaagt aaaatataca gatgccggta cgattcttct
     1801 tgggttgatg ctagaggaaa tttaccaaga aactgcagtg gaaatctttc aagaacaagt
     1861 attggaacca ttaggaatga tgaacagctt atttcttcct tttccttcca aaaaaatcgt
     1921 tcccacagaa caactgcctt cgggtgaggt tttgcgtgga caaactcatg atccgaaagc
     1981 aagagttttg gctgaacatg caggtaacgc gggtctcttt attgatttga aagacagcat
     2041 tacttttgtc caaatgtatt tgaacaaggg aaaaatccgt aatggtcgtt ttttagaaga
     2101 agagacgatt gattctttac tgcaagatca aacaccgaaa aaaaatggct atcgttcttt
     2161 aggatgggac ttaaaaaagg atgtagaaga cggtcatgcg attctttttc atactggtta
     2221 tacaggtacg tttttcttga ttgatataaa aacacaagaa gcgttgatat ttttgtcaaa
     2281 tcgcgtacat cctgtcgatc atcgtgcgga gtatctcata tgtcgagatg aaattgttga
     2341 aaactttttg aaagagaaag cggtattacc gaaataatgc tataatagct atgaaaaatg
     2401 agaggagttt gaattatgca ggaacctatg tttttaaaac cagtttttca agaaaaaatt
     2461 tggggaggaa gtcgtttacg ttcagtcttt ggttttgata tccctaacga taaaatcgga
     2521 gaagattggg cgatcagtgc gcatcctcat ggtgtcagtg tagtagaaaa tggcgaattc
     2581 aaagggaaaa gattagatga actatggtca gaacacaagg aattgtttgg ccatccttca
     2641 gaaccagtgt ttccattatt gatcaagatc ttagacgcag aagatgatct atctgtacaa
     2701 gtacatccag atgatgccta tgggatgaaa catgaaggtg aattaggaaa aactgaatgc
     2761 tggtatatca tcgatgctga acctggtgca gaaatcatct atggtcatca tgcaaagaca
     2821 agagaagaac tagctgagat gatcaaagat gggcgctggg atgacctttt gaagaaagta
     2881 ccagttaaaa aaggtgattt cttttatgta ccaagcggaa cgatccatgc tattggtaaa
     2941 ggaatcatga ttttagaaac acagcaaagt tctgacacga cttaccgcgt gtatgactac
     3001 gacagaaaag atgcgcaagg acaaacaaga gagctgcata tccaacaatc gatcgatgta
     3061 acaactgtcc ctgcgaaaac accagaatta caaatcaaag aagtccgaaa agggaattca
     3121 tcgatcgtca cttatttaga aactgagttt ttcaatgtat atgagtggga tattaaagga
     3181 atcacatctt tcaaaaaaca agccccttat acattgatga cggtaatcga aggagcagga
     3241 gaccttgtcg ttgacggaaa aacatatcca ttagaaaaag gaacaagctg tattattcca
     3301 aatggcgttt ctgagtgggc ggtccaaggt gaactagcaa tcattgcgtc tgaaccaggc
     3361 aaatagttcc cagatagctg aaagcagcag acggtttttc atttgctgct ttttctacat
     3421 aaaatccgtc catcaataaa tagaagtctg gtgaaaaaga tggaatacaa atggaaagca
     3481 aacaacagca gtcgcgtgtc tatgaaacaa ctgagaaaag ctggacatca cttaaatgaa
     3541 atgatcatgc caaatctaag tctgtttatc gcttggggaa tcttgtcatt agcaacaaaa
     3601 ggtgtgtctg gcgatttgca caccacatta gaagaggtat gccattggat gatccagctg
     3661 cttttaccca tcttgatcag ttattcaggc gggaaatcgg tagggggaca aaaaggggca
     3721 gtcgccggtg caattgcttc tttagggttg atcgctcgtt ccaatgctcc acaaatcgta
     3781 ggagcgatga ttatcgggcc gcttgccggc atcgtatatg aacaatttgt ttctagattc
     3841 catgtgaaat tcaaggctgg atatgaaatg cttgtcagca acctactagt aggactgact
     3901 ggtagcgtta tttgtataat tggaatcgtt tttattgaac cagttttaaa tagtgttcac
     3961 ttgttgctcg cctccgttgt gtcttggcta gtcacaatga atctgttacc acttgtcagt
     4021 ctgatcttag aacctctaaa agtactattt ttcaataatg caatcaatca tggtgtattg
     4081 acacctttag gaatcgaatt ctcacaaaca gtcgggtact cttccttatt tttgatggag
     4141 gcaaatcctg gacctggttt agggatctta ctttctatcc tttgttttgc agaaaaacag
     4201 gaaaaagtaa atgcgagtgg agcattgatg atccatgcga ttggcgggat tcacgaaatc
     4261 tattttccat ttgtcttgct gcgaccgtat ctatttttag ctgtaatggc tggtggggca
     4321 agcggcacgt tgatatttca atggttagat acgggattag ctgcacctgt atcgcctggg
     4381 tcactactcg tgatttttgc caatgcgcct tatccacaac tagctggggt aagtataggg
     4441 atagcaatca gtacatttgt gaccttcatt tgtgcagcga tactattgaa attaccaaat
     4501 aaagaaaaag agaacaaaac ggtcaaagaa aggggagaaa tcttggaacc atctatcatt
     4561 cattccgtca tttttgcttg cgactcaggt atgggatcaa gtgctatggg agccgccctg
     4621 ctgaaaaaga aattagcagc agaaaaaatc gatctttctg tcggatacag ctctatctat
     4681 gaattgaata accaagtaaa tcagctggtt atcgtgcaac atgaactagc gggtcttgca
     4741 agagaaaaag tacctcaaag tcaaatctat gtactggatc actttttgga aacagatatc
     4801 ttgctgtcac gaataaaaga agcgatccaa tttccaaagc gggaagaaaa aaaagagata
     4861 gcagatatca cagaacaaaa aacgtcgcct gctaatattg tatttttgta taaaaacaac
     4921 agacgcggct cacaaactat gggcatgacg attttaagtc aattagcaaa aaaagcgaaa
     4981 aaacagtttg ttatctcaaa agaatcaata gaaaaaatca aaatccaaga agaaacgatt
     5041 tatatcgcac aaagagaact agctgtaact gaacagctag aagaaaagat ccctcggcta
     5101 gttctagttg aacattgggt agctacgaat gaatacgaaa aactcgtgaa gggagaaata
     5161 taagatgtat ttatcgccca gagaaaaaca attattagca gaatttctca gtagcccgtc
     5221 acctgtatct atccaaaaaa tgatgaattt attgaaggtc agtaaacgga ctatttaccg
     5281 cgaattagat aatcttgaag tctcattgaa atcggtaaat gcttctttga aaaaagcagc
     5341 tagaggctca tttgtcattg aggcatcaga agaagtatta gagcaattaa aagaaaatac
     5401 agatgggaaa agtaatgact tatccactgc taaacgacaa cacgcgattt tagccgagtt
     5461 gttactgacg acagagccgt tgagtcttgc tcatttcatg gaatcatatc gcatcagtaa
     5521 taccactttt tatgcagata tcaaacagtt ggaagaaagt attcgccaac tgcctttgga
     5581 aatcattcgg aaccagggat acgagatcga aggaccggaa aaataccgcc ggcttctgac
     5641 agcgaatgta ttagaattag aaatcaatga atatgaactt tttcatagta tttctttcga
     5701 tgcatcactg aattattttt ttcgattcgt tgatccgcaa catctatctc ttgcacgcaa
     5761 agtaatcggg gaagaattga tccaaaaaaa gaccaatcta agtgatagaa agcttgaaca
     5821 tttggttttg atgctgacat tgacgatgga gcgtgtgacg aaaaatcatt tactgacaaa
     5881 tgagacatat aatagtctgg caaacaaaga attactacag acagctaaac gattgttttc
     5941 acggatcgct tctgagacaa aacaacttta tccagtaaat gagatcgtct tttttgcagg
     6001 attattaaat gacttcacga actcatttga tcagaatttc tttgaagaga cgttcgatac
     6061 acagcttgct tatttagtaa aacaactgat tcaagaagta agtgaagaga cgaatgtcca
     6121 tttttatgaa gatgaaactt tgtacaaaat gctgttgact catttatctg gtgtgttttc
     6181 aagagccgtt ttacaagaag agacactgac caatccgatt ttagaaaaaa tcatggttca
     6241 atacgaggaa gttgcgaatg caatccgtaa agcagtagag cggatttttc aagaaaaaaa
     6301 attatccgaa gaagagatcg cttatatggt ccttcatttt gcgaattcat tggaacgaag
     6361 tccgaaagaa agcaatatca gtattgcagg attttcgcca agtggattag cttctactag
     6421 catgttggaa ctacgattga aaaggtattt tcccttcatc caacaaattc atttctatcg
     6481 gattgctgat ttaaaaaaaa tcgatttaca agaagaatat gatgttgtta tttctacatc
     6541 tattttacca ggatacggtg gaaaatatat tttagtctcc ccgctactgc tagaagatga
     6601 agtcaagcag ctaaaagaag ctttttcgca tattgagaag aaaaaaaggc aaaaaattac
     6661 gtataacagc aataacgagt ggatgataga agatacttat gaggaaacaa tgcatttcat
     6721 ggatcaaatc aatcaattac tcggtcgttt ttttatccaa gaactggata atcctgagac
     6781 gatttccgaa acgattcgca gcttatttcc ttattttcct gaaggactag taacggatga
     6841 agaggtggtt catcgccggc tgcttaagcg atatgaacaa gcacctatcg gtattcctca
     6901 tacaaatatg gggttattcc atacatccag ctcattgatt tctaaaccga tcttttgtat
     6961 tttcaatttg aaacatccgt tgaccattga agggatggat agacagccag tcgatttgtc
     7021 ccgtatgtta gttatgctgg cgccttcgcc aatccaagaa aaagacggga ttcttttagg
     7081 aaagatcagt ggagcaatca tcatgaatga cttgaacacc gagatcttcc gctcaggaaa
     7141 taaagaaatc gtttatcagt tgttagcgaa aatcctgatt gaagaaataa agaaatgaag
     7201 gtgaaaagat gatacagcta ccagcagaaa aaatattgct cgatcaatcc tatcaaaatt
     7261 ggaaagaagc gttgaccgag atcggccagt ggatgaccca acaaggggga atcaaaccgg
     7321 catatatcca atcaatgatc gaaagacaag aaaaagcgag tgtctatatc gggaatttcg
     7381 tagccttgcc acatgggact gacaaagatg aagaagtagt agaagaagga atctatttag
     7441 tccaagtgcc tgatggtgtg gactttggaa caaaagagga accaaaaatc gcgacactct
     7501 tatttgtagt ggctttaaaa aaagaacatc agttagcggt gctccaagat ttagcctttt
     7561 tctgttcaga catcgaccaa gtaatggcgc tcagtgatgc ggaaaccatt gaagaagtcc
     7621 aaatgatttt tgaacatgga catatataac caatgttcac agtaaaaaaa gctgccttgc
     7681 atcaagtaat aacttcaacc aagataaaaa taagaggagc tatttttgtt gggaggttct
     7741 tattactgcg gatgcaagct tttgaaaact atttattcta gaaaaccgtt tatttgaaat
     7801 aggggacggt gacaaggttt ttgtcaccgc ccctattatt tttgtgtttt aatagctctt
     7861 ttttatatag atagtgccca tacctatgaa taataaaacg atactccata taccaagtgt
     7921 caagatacca ttcatgaaag taacctgttc tgaagctagt ggcgagaaaa tatctcctcc
     7981 tatgatcaca ttttgaaaat caacataaga agttggcaag taatgactga ttgattctat
     8041 ccatccaatc gaagaaaaca agcgatactc tgctaagaaa agacaaagaa gtgtacctaa
     8101 aagattgact agagaatgtt caaataaagc agatagaaga aaactgattg tacttaaaaa
     8161 gagcacccac aacaacagga acagaaagct ctggaaaaga tactcataca tcggcaggat
     8221 tcgtatctcc tgaccaatga tcgttcctac aggataacgg aagtctccca aaccattttt
     8281 gattattact agtatagaga cgatcaaaaa tggcatcacg agacttagca tagctgcacc
     8341 ataataaatg gtaaaacgga tgctatgttt ctttaccata ctatccggta atagattgac
     8401 tagagagatt acctgctttc ttttttcata agagatgatg gaagaaagaa acaaggcggt
     8461 tatacataaa atcaaaaaac tagaaatcat tcctgaaaaa atattttcgt agtaatttgc
     8521 taaagagaga tgcgctggca agtcaaaaat agaatatctt tggatctgat gttctttcat
     8581 ataacggagc aactcgacac gtttttgttg ttcaatgatt ggaattcctt gtctttgacc
     8641 agaaatcagt cgatccagta tatctttttc ataatgataa gttgcttcga ccatttgctg
     8701 gacattccct gtgttttttg catgtaagat tgcttcgatc agtttgttgc ttttctctaa
     8761 actttccaca aattctttct cattctcatc ttctttcaac gtttcaatca aacgttgcat
     8821 ctcttcatag ttatgattca gttcatcgaa ttctgtataa gcaagtttat gatcaaaaaa
     8881 aagtgggaat gcaaagagca cgaccaacaa tagaggaaat aaaaagttta ctttgttttt
     8941 tagtaagaga ttgcgttcaa atgtaagtaa agacatagtt acacctcata taatttacga
     9001 taaatagcta aaatctcttc catatttgag gattctgtga cgatttctcc attttttaga
     9061 aaacatgctt tagaacaaat cgattggata ttcgcgatag cgtgggaaga aagaagaatc
     9121 gtcttcccct ctttctgcca ttgtctgatg aggctattca agatatcaat acttcctggg
     9181 tctaatccgt tcaacggttc atcgaataac atgacagatg aatcactgat caagtaagca
     9241 gcaagcaaga catgttgttt cattcctaga gacatttttc caatcggcaa agtaaggtac
     9301 tcagtcatct tcaatcgttg gaaaacagtt tggcattcta ctttgctctg ccaatagtat
     9361 ttgatcaaag tcaaataatc aacagccgat agatagtcgg ataactgatt cgttgattct
     9421 agaaaaaaga aagaccggcg ataatctgta taagcagtag gagagatgtt gtgaagggac
     9481 aattgatcat aagttgttgg cagcagttgg gcaatgccat tcagcaaagt tgttttgcca
     9541 aatccgttcg gggcaatcaa agcagctact tctcctgatt ctactaaaag attcaattgt
     9601 cgaatcacac gttttttacc acgtttcatg ttcatgtttt tgatcagtaa tgtcatagat
     9661 aggcctccaa tataaaattt aataacataa tagaatggaa aacatctaaa ttaaatgcta
     9721 acaaaagtta ttgtttgcat attataaaaa aattaaaata acagttttat ttaaaattga
     9781 agttttctga taccgaaatc tttttatttt gctgacatac tcaaaccttt ggcacaaagt
     9841 ttcgtgccaa agtacgacta tttctctttt tagtaagcgg atacaattag agtatcaaaa
     9901 ggagagaggg agagacaaaa tggaacggac gattcccaaa aacaacattt cgctaaaagc
     9961 gagggtacaa aaattaggca gtactttatc aagcatggtc atgccaaata ttggagcact
    10021 gattgcctgg ggtgtattaa cggctctatt tatcccagat ggttatttac caaatgaggc
    10081 tttcgctacc atggtaagcc caatgctaac ttatctgatt cctttattga tcggttatac
    10141 tggcggaaaa gtaattgctg gtgaccgcgg atcagttgtt ggggcaattg caacgatggg
    10201 tgtgattgtc ggaacagata ttccaatgat gctaggcgcg atgatcatgg gacctcttgg
    10261 tggatatgcc atcaagaaat ttgatcagct attccaaaaa cggatcaaat ccggttttga
    10321 aatgctagtc aataattttt cagcaggtct tatcggtttt ggattagcgt tattaggttt
    10381 ttctgcgatt ggtccagttg tcgatgcatt gactcaagca atggcaaaag gtgtagagat
    10441 cattttatct gcccatttga ttccattgac aagtattttt attgaaccag caaaaatctt
    10501 atttttgaat aatgcaatca atcatgggat tttgacacca ttgggaactg aacaagtagc
    10561 agaggctgga aaatctattc tattcttgct tgaagcaaat cctggtccag gacttggcgt
    10621 attacttgct tttactttgt ttggcaaagg agcagcaaaa tcttcagcac caggagccat
    10681 gatcattcac tttttaggcg ggatccatga aatctatttt ccttacgtta tgatgaaacc
    10741 gttattattc ttatcagtta taggcggagg aatgtcagga agtttcattt tccaattgat
    10801 ggatgctgga ctaagagcgc cagcttctcc agggtcgatc attgcgattc tagcgatgac
    10861 accgttcaat tcttaccttc ctgttatttt gggcgtgatt gttgccgcag ctgtttcgtt
    10921 tggtatttct gcagtaattt tgaaagcgga tgcgaaagat acaaatgaag acttcgaaaa
    10981 atctgttcaa gagacaaagg cagctaagca agcttccaaa ggtgcccaag gtattcctca
    11041 aggagctaca ttctctggcg tacaaaaaat catttttgct tgtgatgcag gaatgggatc
    11101 aagtgcgatg ggcgcttcga tcttgagaaa aaaagtacag gaagcagact tgcctcaaac
    11161 ggtgaccaat caagcaatca gccaactgac agatgactcg aatacattga tcgttactca
    11221 ggtcgaacta caagaaagag caaaacaaaa agcaccgagc gcgcgttttg tctcagtaga
    11281 aaactttttg aattcacctc gatatgatga aatcattcaa gaattaagca gcaagcagaa
    11341 aacatcagtt tctgaaattg agaatgagcc agcagaagag tttctttcag caaacatcaa
    11401 acaaatcaaa gagattctac ttgtccacga tgatcgttcc ggatcagcaa caatggggat
    11461 gaccgtgctc aaagatatat tagacaagaa ccatttaact atcccgttaa gaaaagtcaa
    11521 tatccaagat ttaaaagatg aacctgattc actgatcgta gccaaagaaa gtttagcgga
    11581 aaaagtacag atggctgcac ctcaatccat tcatttatca gtcaacagca tggtcaatcc
    11641 gcaaaaatac gaatcgattg cacaatattt gaaacagaca gcttaaggga ggaaaacagc
    11701 atgcaaagtt tgccattcga catgatcgag ctcaatcgat cttttaaaac caaagaagaa
    11761 gcgatccgct attgcggtca gatgcttgta gaagcagggt gcgttgatga ggaatatatc
    11821 gatgccatgg tagatagaga caaaatgtta tctgtttata tggggaattt tatcgcgatt
    11881 cctcatggaa cagatgaagc aaaaaaatat gtgaaaaaat ccggcatctg tgtcgttcaa
    11941 gtaccagatg gtgtagattt tggtaccgaa gaagaagaaa agattgcgac tgttttgttc
    12001 ggtattgcag gagtcggaga tgagcatttg caacttgtac agcaaatcgc actttattgc
    12061 agtgatatgg acaatgttgt ccagctagca gacgcgctca gcaaagaaga agtaacggaa
    12121 aatctagcaa ttgcttaagg agagagaaaa atgagagcag tacattttgg tgcaggaaat
    12181 atcggtcgag gatttattgg agaggttttg gcagctaatg gatttgagat tactttcgta
    12241 gatgtgaatc acacgatcat tgatgcttta aatgaaagaa aagaatacga aatcgaatta
    12301 gcagatgaat caaaagaaaa aatcactgta aaaaatgtca aaggaatcaa caatcaaaca
    12361 aatccagaaa aagtaatcca agaaatcgct gaagcagatt tagttactac cgccattggc
    12421 ccgaatatct taccttttat tgctgagttg attgcaaaag gtatccaaga aagagaaaag
    12481 gaaggaagca caacatcttt agatatcatt gcctgtgaaa atatgattgg cggttcagca
    12541 tttctagaaa aagaagtgta taaatatctt ccggaaacat catttactga caaatatatc
    12601 ggctttccaa atgcagcagt cgatcgaatc gtcccattac aacaccatga agatccttta
    12661 ttcgtccaag tggaaccttt caaagaatgg gtcattgacg atagccaaag aaaaaataaa
    12721 aaaatccaat taaaaggggt tttatatgta gatgatctag aaccatatat cgaacgcaaa
    12781 ctatttagtg tcaatactgg tcatgcgact gtcgcttata caggtgcctt gttaggttac
    12841 cagaccattg atgaagcaat gcaagatgcg ttagttgtgg cacaattaaa atcagttttg
    12901 caggaaacag gaagtttgct gattgccaaa tgggggtttg atgcagagca gcatcatgcg
    12961 tatattgaaa aaatcattca tcgcttccaa aacaaaaata tctctgatgc gatcacacgt
    13021 gtcgctcgga caccattacg taagttaggt tatcaagaaa gatttacacg tccagtgaga
    13081 gaactacaag aacataactt gacttgccca catttgacgg caacaatggg gattattttt
    13141 aattactatg atcctgaaga tgaacaaagc cgtcaattgc atgaaatgaa gatccatgaa
    13201 aacttggaac aattgattca agaagtcaca ggaatcaatg atccgaaaac aatcgggaat
    13261 atcaagcaaa acgtgaaccg ttatgccaag caagtcgctt aaaataggat acgaaaaagg
    13321 ggaatgtgac gaaatttttg tcacattccc ctttttcgaa taactaggct gtttgtcctt
    13381 caagataggg cagatccaat tctttaccgt aacgttgttc taaagctagg cggatcaaac
    13441 gagctgccag gttctcattt cttgcaagga taggtccatg gaaataagaa ccgaagacat
    13501 ttcggtaaat gacaccttca gattggtctt caccattatt tccttgacct tgtaccactt
    13561 tccccaaagg tcgttcacct tcacctaaga aagtccgacc attgtggttt tcaaatccat
    13621 aataagtttc attgaattct tcgttatgga taacgatatc accgataaac cggttatttt
    13681 cctgacttaa cgtgtagtga tccagtgcac tgattccttg gatcttttct ccattagctc
    13741 ccatgtagta gtgacctagc aattggtagc caccacaaat ggctaacatg acgccatcat
    13801 tttcgatata gttgatcaaa gaatctttct ttttctggat gtcttttgaa atgattaatt
    13861 gctcaaagtc ttgaccaccg ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt
    13921 catgtatact aacgatctcc gtatggcaag aaacccccat tttttctgct atatatttca
    13981 acatcaaaag gtttccgtta tcaccatatg tgttcatcaa atttccataa aggtgggcga
    14041 tattgagttc ataattagcc acggttcatt cctcctttga taaatccttg agcagctagt
    14101 tctttacgaa gctgcaatac agcagtgtaa gtagctaaaa tatagacatg ctcagttggc
    14161 aattctttga ttttttcgat tacttctggt aattcttttg tttctgtcaa tttattttct
    14221 ggaatcccgg caacttttag acgtaaagtc atatctgtat gacggtctcc tccagaaata
    14281 acagctggga tatccatatc ggcaaagttt tcaaaattac catcccaaat ccagctgaca
    14341 tcgattccgt ctgcgtaatt ggcatttaat aaagccacta aagaaaatgg ataaggagct
    14401 agaccaatca tatcgattac ttgattgata cctacaggat ttttgacaag tactaatgta
    14461 cattttttcc cattgatatt gatgacttct tgtcggccga atactttctc gtcatatcct
    14521 aaaccttgtt tgattttatc aggatcgaca ttgaagtact ctgccactgc agtagctgct
    14581 aaagcattgt agacattata cataccgcca acttcgattc cgtattcatg accatcgatc
    14641 acgaaatctg ctgacacatt gtccatccgt accatatcag ttaatcgata atccaattca
    14701 ggacgtttga agtcacaatt tggacagtaa tatttcccta agtttgcata agtgatcatt
    14761 ttataatgca agatgtgatg acaatttgga cataagacac cgtctgtatt gtaatgagcc
    14821 atttgttcac gatcttcttc atggtcaaag ccataatatt ttctaggatt gactgtttcg
    14881 atagaattga agattggtga atcaccgtta ctgataatcg ttgcatttgg tgactttgcg
    14941 gcaccgtcta caatcatttt ataggtcgta tagatttctc cataccgatc catttgatca
    15001 cggaaaatat ttgtaaataa gaacagttct ggtttcatat attctgtgac tttgctcaaa
    15061 cttgcttcat ctatttctag gacagcaaac tttttctgtc ctttttttgg ttttgcctgc
    15121 aagaaagtcg atacaattcc ctgtaccata ttcgcaccag tagggttggt tagaacttca
    15181 tcgaattgct ggcgcaaaat attgactgtt aaagcggtag tcaatgtttt accgtttgtt
    15241 ccggtgacaa cgacgacttg gtagtctttt gccaaactat ctagtatatg tggatcgact
    15301 ttcagcgcta gtttacctgg taaacttgat ccgcctttaa aaaaagtttt taatgcccat
    15361 tgcgacgttt ttccaactgc aatcgcaaaa tgactgcgta ttcccattat gtaacctcca
    15421 aaaacgattt gctgacgaat aaattcaact aatcatacca tatgttgaaa aaaaggttaa
    15481 attgcttttc ttattcttaa gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat
    15541 cgcatgattt aacaaaaaaa cagcttgaaa caaaatgatt gtttcaagct gctgtgattt
    15601 tattattccc tcttacctat attcccattt taaccgataa taattttctc gcttggatat
    15661 tcatagccta gatctcgtgt ttcttttggc acgaataaca tcaatgtata tagcattccg
    15721 atccgcccaa taaacatcag tgtagcaatc gtgattttgc ccacaacaga caagtctccg
    15781 gtaatcccta aagataaacc agttgttcca aacgcagaag ttacttcgat gatgatcgag
    15841 atcagcgttt gttcttctgt agcagataaa aaaacgatac aaaagaaaca cataccaaga
    15901 gaaagcataa agacaacgac tgattttcgc acatcatctt gatcgattct ccgtccaaaa
    15961 atattgatgt tatcttcact tttgaggaag gaatatagat acaaaccgat gattgctaca
    16021 gtagttgttc gaatcccgcc gcctacagaa ctaggactgc atccgataaa catcagtaaa
    16081 gaaaaaatga tcagtgttgt gatttgaaaa tcacccaaat cgtgaatctg cagaccagca
    16141 ttacgagtcg taatcgaata aaacatcgaa ttgatccatt tgacactcat attggaatct
    16201 tggaataaat ggtccttttc caatagataa atcaagacag ttcccgaaac aaacaagata
    16261 acaaaagcta acacagctaa tttggtaaac aaggaaaaac gaaacggaag cttcgcattg
    16321 gaacgtttgt ataatagcca ttcccggcac tccatcaata caggaaaacc aattcctccg
    16381 acaaaaatca aaaacatgat caggatcaag aaaaaatagt catgtgcaaa gggcttgatg
    16441 gaatccccag tgacgtcaaa cccagagttc gtgacagccg atatcgcctg ataaaaaccg
    16501 taaaaaacgg catcacgcca acgatcaaaa tagcctctgt aataaaaata aatagaaaag
    16561 aatgtcccaa aaagtaattg aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg
    16621 acgataccag acaaacgcgg ttgattcata tccgtcatga tcagctgtcg ctgtttcagt
    16681 gtgatccgtc gtttagaaaa aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca
    16741 ccaacttgaa ataatatttc cagcagtata ataccgttat cattgaacac agaattgata
    16801 tcaaaagtcg atagtccagt cacactcact gtactgattg ccatgaacag catgtccaca
    16861 aaagaaacat ggctatctgg ttcgcgaaaa atcggcatat aaaatagaac gagtgataag
    16921 accgtcatca atatataata aaaaacgatg atttggatcg atgagaaatg attggcagca
    16981 aacttctgtc ctcgccgctg cagccttcga aagaataaat caacatgcac agtactatcc
    17041 tcctgacaat agtcgtttct accagtatac aaggggaatt aggaatactc aaagaaatta
    17101 tcaaacagat aacaatacag ctttcgatta aaatagaaat ggcttataat aaggaaaatc
    17161 ctagaaaaaa gaaggaggag gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa
    17221 atgaaaaatc aaaaaataaa ttatgataca gttctgaaaa aaatgatcat gcaatgggag
    17281 aaagaagaag taaagcctaa gatattaata catacatgct gtgctccttg cagtacgcac
    17341 acattggaat tcatgtctca atatgcagag atcacgttat ttttttcaaa ttcgaatatt
    17401 catcctaaaa gtgagtattt gcgaagatta catgaacaaa aacgatttgt agaccaattt
    17461 aatgagaaaa ctgaccatca tgttgcgcta atcgttgatg aataccgtcc aaatgaattc
    17521 accaaaatgg ttttaacaaa ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt
    17581 gcatgcttca atatgcgatt agatcttgtt gcgcaaaaag cgcaagaact aggatacgat
    17641 tactttggaa gtgccctgac catctcgcca aagaaaaatg cagctttgat caatcagatc
    17701 ggaatggata tccaaaagat ttacgggaca caatacttgc caagtgattt caagaaaaac
    17761 aaaggctatg aacgctcttt gcaaatgtgc aaagagtatg atatttatcg ccaatgttat
    17821 tgtggttgcg tgttcgctgc caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa
    17881 gcaaaagctt acttaaaaac atcaaccgta gtttttgagg aaaattaaag aaatctttcg
    17941 gaaaaacgta agaaaaaaat aaagaattta tggtagaaat aaggtagact gtataatttg
    18001 tccgtagtaa agtaaggaaa caagaataaa tttcaatgaa ggaagagata agatgcgaaa
    18061 agtagcacct attttgaagc caatcgctgt attaacaatc tcgacgattg tcgcgactac
    18121 tacaggtatt gtgaatagtt ccagctaccg tgcaccaagt tcaagttcta gtactgtaga
    18181 agaaacaaca ccaactactt cagtctcgac atctgaacca acaacaacgg aaagtttgaa
    18241 tgaaaccact acgacaagta catgggacga tacaacaact agttcgtcgt atgatgagac
    18301 atatacaact gacagctcaa gcgaaacaag taatacggta ccagatggca ctccatcgga
    18361 ttcaaccaat ccaagtacaa gtccggatac aagtgctagc tccgaaacga taccaagcag
    18421 tacgactgta gatgataaca cgcaaaatga tgatgcagca cgtacagcac agcaaaacca
    18481 agattcagga aatacccaaa cgtataacca gcaagcaggt gattctcaat gacattttta
    18541 ctagacctta tcaacggggt gcataaattc cttggctatt tagacatcag tcctaaatat
    18601 cttaaccgtg gatatacgat tttaagtgtg attcccacgc tttatttatt gagaattgtt
    18661 tatggacttt ggcaaaacca aaactatctt caatttttct tatatggact tgcatttcta
    18721 gtgcttgttt attttactgt tttaaatgta ttttattact ttttagataa aaacacgaaa
    18781 gccgatgtca ctcagctttt tgtgaagtat ttacctgatg aagcgttcaa catccagaca
    18841 gaagaatcga tagataatgg aaattcgatc gataaagtga atacacaaga ggtcatggtt
    18901 tcttatgacg aagattatca attgaaatta gccgagaata tgcggtattt gattggaaat
    18961 ggtgagatca aaacaaatga actcggtcgc atggatggat ttctggtcga tagaaataca
    19021 ttgtatcctt attactatgt caagaaaaca ggagagaaag agtatgttct aaatattgga
    19081 cgaagctact cggacatgga aaaagtaggg accattcgac ttgactcaac agaagacaca
    19141 ttggaacctg tcggattgtt catcgtcggc ggtgattttg tcaaagacgg gttacgctat
    19201 catgagcctt atcgtctgaa attgattgca aaaaaggcac agtcgcagga agaaccagtg
    19261 gtttatagtc gtagccaaag aagaagacat tcataatgtg atgaaacgcc gtgtatcagt
    19321 ggttgcgata aaaacgttta ttcggaataa gggggatgtg acacgtcttt tgtcacgttc
    19381 cttttttata taacgagaaa gataagacga acacatcact tattctttcc tttcatttat
    19441 aaacattgta gaataaagaa agtacaacga agtattgtga aaaaacgtaa taaataacga
    19501 ggaaaataca agtaggaggt aagctgtgaa agaatttttg aaaaattggg ggattttgat
    19561 ccttgtatta gcggctattt tattagctag agtgtacgtg tttacaccag ttactgtaaa
    19621 cgggcattcg atggacccta cattaagtga tggacaacga ttgatttcat ctaagatctc
    19681 aaactatgaa cgaatggata ttattactac aaaggaaccg ggggatgaag aacggatgat
    19741 tgttaaacgg atcatcggta tgcctggaga tacagtcaag atggaaaatg accagttgac
    19801 cattaatggc aaaaagtatg atgaacctta tctggatgag ttcaaaaaag aattttcaga
    19861 agataagtta caaggagaat atgcttatag ctcaggattc caagcacaag cagaaagttc
    19921 atccaccttt acgagtgact ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg
    19981 cgataaccgc ttgatttcaa aagacagccg aatgtttggg ttagtcgaca aagatatgat
    20041 ccaaggaaaa gttgttttcc gttattggcc tctttcagaa attaaaatca tgtgatgaaa
    20101 aaataaaaag aagctgtgac atgttttttg tcacagcttc tttttccgaa aattccttct
    20161 tatttcttgg agttgctcac tttttttgca atctcatttt aagctttttg gctgatggat
    20221 aagaaaagcg aagcgttttt gttcataaat agcttttccc cacgatggaa ggtatgacta
    20281 gtagcagaga caaagcccgt tttttccaat cgattattca attcttcttg gctaaagcca
    20341 ttatggactt tcggatgact aatttgttca ttcttgtcaa agtctacgat gatcaattga
    20401 ccgccaggag ctaaaatttc ataaagtttt gtaagaatat tctccgtatc aggaatgtgt
    20461 aaaagtacaa gtgatagaag gatgagatta gcttggacag caggaaattc gacagaagca
    20521 tcagcgtgga tcgttcggac atttttcaga tctgctgctt ggatcttttc ttctgccatt
    20581 ttcagcatag tttctgaagc atcggcaatg atcagttctt tgaatctttc cgcaagcggt
    20641 aaactaacaa gcccagttcc gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc
    20701 ggtagataag tagttagttc ttcgcgaata atcttggcta atgcttgacg gtcaggggaa
    20761 tcataatggt tagcgatgga atcaaaaata ttttttgtca tcaaatagct ccttacgtaa
    20821 aactttgaaa ttttaactta ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat
    20881 tcaaaaaggg agaatctaga aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa
    20941 aaggaaagtg tgtccgagaa atattactag acttgcctga gtggtttggg cttcctgaat
    21001 caacggaaaa atatatcgag gaatcaagta aactaccttt atggtgtgaa aaaagaaaag
    21061 aagaatattt aggctttatc actctttcac agacaagtga agatactgcc gaaatctatt
    21121 ctattgtatg ggaataaaaa aagactatca tcaccaagga ttaggaacaa aactttttaa
    21181 agaagcagaa ggttacgcag caaaacatta caaatatttg caagtgaaga ctgtagacga
    21241 ggggcactac tctatatatg atcaaactat ttgtttctac gaatcattag gattttcaag
    21301 gttggaagtt tttccaaatt tatgggatga atggaaccca tgtttagttc ttgtcaaaaa
    21361 attggaacaa aagtgagcaa tagatttaat actaatctgt gcttgatgaa aattctcact
    21421 gtaaaaaatg ctgaaaatca agtataatac cataggaaca aactggaagg tgaaaaagag
    21481 catggcacaa ctatttttta agtatggcgc aatgaatagc ggcaagacga tcgagatcct
    21541 aaaagtcgca cataattatg aagaacaaaa taagccagtt gtcttaatga caagcggtat
    21601 tgatacaaga gatggtttag gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat
    21661 gccgatattt gaagaaacag acgtatttga cgtaattcag aaaatggaaa gcaaacccta
    21721 ttgtgtgctg atcgatgaag cgcaattctt aaaaaagaaa catgtcattg cttttacgag
    21781 aattgtggac gaattggata ttccggttat ggcatttggt ttgaaaaatg attttcgaaa
    21841 cgagttattt gaaggatcaa aatatttatt gctttatgca gacaaaatcg aagaaatgaa
    21901 aacaatctgt tggttctgcc acaaaaaagc aatcatgaat ttacattata ttgatggaaa
    21961 ccctgtttat gaaggcgatc aagtgcaaat tggcggaaat gaagcttatt accccgtttg
    22021 tcgaaaacat tactttcacc catcaatgat tacagaagga gaataagcat gtacgatcaa
    22081 ttacaagcaa ttgaagaccg ttatgaagag cttggagaac ttttaagtga cccagaagtg
    22141 atttctgata caaagcgttt tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca
    22201 gtcgaagttt atcgtcgtta taaagaagta gtacaaggaa tcaccgatac agaagaactg
    22261 cttggtgaaa aactggatga tgaaatggct gaactagcaa aagaagaatt atctgaatta
    22321 aaaaaagaaa aagaagtctt agaagaaaaa atcaagatct tgcttttacc aaaagatcca
    22381 aatgacgata aaaatatcat catggaaatc cgtggagcag caggcggaga cgaagcagca
    22441 ttattcgctg gcgatctttt caatatgtac caaaagtatg ctgaagcaca aggctggaaa
    22501 acagaagtga tggaagctaa cgttaccgga atcggtggat ataaagaagt gatcatgatg
    22561 atcaccggag acaacgtata ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag
    22621 cgtgttcctt caactgaatc gcaagggcgt atccatactt ccaccgcaac agttgtcgtg
    22681 atgccagaag ctgaagaagt agagatcgat attgaagaca aagatatccg tacagatatc
    22741 tatcatgctt caggtgctgg cggacagcac gtcaataaaa cagcatctgc tgtacgtttg
    22801 actcacttac caacagggat cgttgttgct atgcaagatg aacgttctca aatcaagaac
    22861 cgtgaaaaag caatgaaaat cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca
    22921 caaagcgagt atgatgccaa tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg
    22981 atccggacgt ataatttccc gcaaaatcgt gtgactgatc atcgtatcgg attaactatc
    23041 caaaaattag atcagatttt agcagggaaa ttagatgaga tcgttgatgc attgatcatg
    23101 tatgatcaaa catcaaaact ggaagctatg caaaatgggt aaaatgacct atcgagaagt
    23161 cctgtcacgg gcttcttctt ttttagagga tcatgggaaa gaagcatata gtatccaatt
    23221 tttatttttg gaacgaaaac aatggaaaaa acttgattgg ctccttcata tgaacgaaga
    23281 gatttcagaa gaagaacagc ggttgatcga aaccgatctg cgacttctgc ttgcagatca
    23341 tccacctcag tatttgctag gatatgcaga tttttatgat catcggttaa aggtaactga
    23401 agcaacactg atccctcgac cagaaacaga ggagttagtc gaatggtgtt tagacgagac
    23461 gcctggtgta ccgttagaag tgatagatat tgggacaggg actggagcaa ttgctattag
    23521 tttgaaagca gcaagaaaaa attggcatat atctgctgtg gatctttcag aagaagcatt
    23581 agaagtagcg aaagaaaatg ctcagaaaga aggaacgaaa atcagttttt atcatggaga
    23641 tacattagga ccagtaatgg atcagcaatt tgatgtgatt atttctaatc cgccgtacat
    23701 cagtcggaat gaatgggaac tgatggatga aagtgtccgg tcattcgaac ctaaaatggc
    23761 cctttttgct gagaacgatg gattagctat ttatgaaaaa atagcagttg aagcaccaag
    23821 cgtactaaaa tcaaatggaa agattttttt agaaatcgga tttcgccaag gtgaagcagt
    23881 aaaaaaaata tttcagcaag catttccaga taaaaaagtg gcgataaaaa aggatctttt
    23941 tggcaatgaa cgaatgatcc aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt
    24001 gtttttttat tataaaaaaa cacttatttg acaaggatgt aaacgacttt ttggtttatc
    24061 aacaagttta tccactattg acaaatagat tatccacaaa cagtggaaaa cttgaggata
    24121 aactcagaca aaataagaat gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac
    24181 gatatgatga aacagaattg caagaggcag ccgaagcact gaaagaagga gaacttgttg
    24241 cttttcctac cgaaacagta tacggattgg gcgccaacgc tcttttacca aacgctgtca
    24301 agaaagtgtt ttctgtaaaa gggagaccgc aagataatcc attaatcgtc catgtcgcct
    24361 cttttgaaca agtaaaagag tatgtggaca actttcatcc ggcagcagag aagattgtga
    24421 agaacttctg gcctggacca ttaactttga tatttaagat caaaaaagac actttgccct
    24481 cagttgtgac gggaggatta tccacagctg catttcgtat accggataac aaaaaaacac
    24541 tagaagtaat cgaactttcc ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa
    24601 aaccaagtcc aacgactgca gatcatgtat atcatgatct acaaggaaaa attaccggga
    24661 ttattgatga tggagctacg cgaattggtg tagaatccac tgttcttgat ttaagtgatc
    24721 caacagccat gcctatgatt ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag
    24781 tcatcgaatc tcctgttgct attgatcagc atcttgtaaa agaaaatgaa acaccaaaag
    24841 cccctgggat gaaatacaaa cactactcac ccgatacacg tgttctgatg gtcagagatg
    24901 gcgattggtc aactgcagtt caatgggcaa aaaataagaa gatccgtgca ggtgtcatag
    24961 caagccccga aattgcggat caagtgcgga cagatactgc agctgtttat atgtataacg
    25021 acaactcagt agaagcggcg gctaaaggat tgtttgcagg tctaagagga ttagatgaac
    25081 caacacttgg attagatttg atttttgtac aagtgtatcc agaaactgga ttggggaatg
    25141 cttacatgaa tcgcttgaaa aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg
    25201 gttattgtcg cattctttta gtatgataca atgctatcaa gtaaatcttc tatcagtgaa
    25261 cgaaaaacta agcgtaacta atcgtaatag aagagatacg aatatttggc aatttgtttt
    25321 tgatgggaaa aataaaattg taggaaaata aaaaggagct gttgtttgtg gtagattaca
    25381 aaacgtttga ccctgatctt tgggctgcga tcgccaaaga agaagaaaga caagaacata
    25441 atttggagct gattgcctct gaaaactttg tctccgaagc agtgatggct gcacaaggaa
    25501 gtatcttgac aaataaatac gcagaaggtt atccagggca tcgctattat ggtgggtgtg
    25561 aatttgtcga tatcgttgaa aatttagcga ttgaccgtgc aaaagaatta ttcggagcga
    25621 aatttgcgaa cgtccagcct cactccggct ctcaagccaa cacggctgct tatctcgctt
    25681 tggtagaacc aggggacacg atcttaggaa tggatctttc cgcaggcgga catctaacac
    25741 atggatcacc agtcaacttc agtggcaaaa cctatcactt tgttgcttac ggtgttgatc
    25801 cgacaacaga agttattgat tataatgtgg tacgtatttt agctagaaaa catcaaccaa
    25861 aattgatcgt agcaggtgcc agtgcttacg gacgaacgat cgactttgcg aaattcagag
    25921 aaatcgcaga tgaagtaggc gcaaaactga tggtagatat ggcacatatc gcaggattag
    25981 tagcagcagg acttcatcct aatccagttc cttatgcaga tatcacaacg actaccactc
    26041 ataaaacatt gcgtggccct cgaggcggca tgattttgac aaacgatgaa gcattagcaa
    26101 aaaaaataaa tagtgcggta tttcctggta ttcaaggcgg ccctctagag catgtgattg
    26161 cgggtaaagc agtagcattc aaagaagcat tagatcctgc atttaaagaa tatagtgaac
    26221 aaatcatcgc caatgcaaaa gcaatggtca aagttttcaa tcaagcaatt ggaaccagag
    26281 tcatttcagg ggcgacagat aatcatctga tgttgatcga tgttcgcgag ttaggtataa
    26341 atggaaaaga agcagagagc attttggaca gtgtgaatat cactgtaaat aaaaactcga
    26401 ttccttttga aacactaagt ccattcaaaa caagcggtat tcgaatcggc acgccagcaa
    26461 tcactactcg cgggttcaaa gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag
    26521 cattacaagc aaaagatgat aacgctcaac tagacgaagt caaaacaggt gtacgcgaat
    26581 taactgaaaa atttccgttg cataaaaaat aaaaatttaa attccattag taaacagaaa
    26641 agttcaatgt tgggcttttc tgtttatttt ttgggaaaac ggattctttg acaatatcgg
    26701 tgatgctctc tagtatatga ggtgtaattt tagtcttcac actaaatctc agggaggaaa
    26761 agtcatgact gatcgtatct cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc
    26821 gcctcatccg cgtatctatg aactagcacc ggaagaagga agagttttac tagaagaagt
    26881 acaagaatca cctgtgaaca aatattccgt cgatattgaa gacttgatgg tggatactgg
    26941 cgaatgggga aaactcaata ttcgtctcgt acgaccagaa gggaatatgg ataaattacc
    27001 agttattttt tatattcatg gagcaggctg ggtttttggc agtgctcaaa cccatgataa
    27061 attgatcaga gaacttgcgg ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg
    27121 atcaccagaa gcaaaatatc caacagcaat tgaacaaaat tatgctgtgt tgcaacagct
    27181 gaataaatta gccaagtcaa aaaatctgga tctcgagaat ctaatcgttg caggagattc
    27241 agtaggtggt aacatggcta cagtcatgac gatcttaaca aaagaacgaa agggcctccc
    27301 aatatccaag caattgctgt attatccagt cacaaacgct gattttgata cagattccta
    27361 tcatgaattc ggagaaaact attttttgac aagagaagga atgatgtggt tttgggacca
    27421 atatacgacg aatgaagaag agcgtgctga aatcacagct tcgcctttga gagcaaatat
    27481 aaatgaacta aatgatcttc cttcagcaat gattttaacg ggagaagcgg atgtattaag
    27541 agatgaaggt gaggcttatg cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt
    27601 acgcttccaa ggaatcatcc atgattttgt catggtaaat gctatggatc agacaaaggc
    27661 aacgcgtgca gcaatggcat tatctacttc ttggatcaag aaaaaagaat aagctttgct
    27721 tgtccgcagg aaaacttctt ttcaaaaacg tattttctta ggaaaaatgg cgagtttgac
    27781 tagtcaatca cttgattttg ttttacaatt aaaaagaaac gacagaacaa aggagagctt
    27841 aaaaaatggg caaatttcaa gtgatcgatc atccattgat tcaacacaaa ctaactatta
    27901 ttcgggacaa aaactgcgga acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt
    27961 tgatggcata tgaagtatca cgggatatgc cattggaaga catcgtgatc gaaacaccga
    28021 tcactgaaac aacacaaaaa acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc
    28081 gcgcaggtat tggaatggtt gacggtatct tggaattgat tccagctgct aaagtgggac
    28141 atatcggtct ttatcgagat gaagaaacat tggaaccaca tgaatatttc gtcaaacttc
    28201 cagaagacat tgatgcacgt cagttgtttg tagtagatcc aatgttggca acaggcggat
    28261 cagcaatcat ggcaatcgat gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt
    28321 gtttggtagc agcacctgag ggagtaaaag ctttgcaaga agcgcatcct gatattgaca
    28381 tctatacagc ttctctagat gaaaaattga atgaacatgg ttatatcgtt cctggactag
    28441 gggatgcggg tgaccgtttg tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac
    28501 aacttttgtc acatcctttt ttggtcattt ttaacgtttg atgcagaaca gctttttcac
    28561 agctttcgtt tgcatataaa aaaaccatcc caaaaatgca gagatggtca aattcaaatc
    28621 ttttttagtt ctttgtagtt aacgattact acacccttac tttgcgtcat caagttcgca
    28681 ttttctgcag tttcatcaat ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt
    28741 ccagtttgcg acttgccgtg aattgtgaac attacgtgag tattgatctt gaatttttca
    28801 ccaatttccg atggtacgat agttgtatca aattttccaa aagttgccat tttcataaaa
    28861 cctgcctttc acatcaatta taccacgttt tatgaaaaat atcatgaaat taaactaatt
    28921 ttccatcgga ctctttacaa tcagccaaat agagtatata atttcttttg gataaggcca
    28981 gcttagctca gttggtagag caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta
    29041 tagctggcat taaaagagaa gacagatata tcaaggattt ttaatccatt gatacatctg
    29101 tctttttgtt taaaggaaat aaagtatgct ttcttagcaa tagagcatgt attatttcta
    29161 taaaaattta ggagaataaa acgactagca atatagctgt gaaatcaaat atcacatgaa
    29221 ctgcccaact tgtaatgatc gagttgcttt taatggcagc ttggttgaat aacaatcttg
    29281 ccaccccttg tatcaaaagg atgtgtgcta cagtgtgtaa aatatttcca ttatcataag
    29341 tactgtaatg gataaatcca aagatgattg ctgacaagaa actagcgaca ggaatgctga
    29401 acttactaga aaaaatagcg agaaaataca ctgagaacaa ttcttctcca agtatcatga
    29461 taggcaaaat aataaataat aacgggctga aagcctcatt tattggattg cctgttaaac
    29521 cccatttcaa aatttgttgc aaaaataccg agactgcggc actgattact acattgataa
    29581 aaaaatattt ggctatattt ttgacaggag cgacaggttt cgagaacatt tttttcgtat
    29641 cttttttacc aaaaacaagt gtaaatgcta taaatccagt gatagttaaa gaaaaaatgc
    29701 taataatgga tggcgcaaat agcaacccta acaaaccgag tacaacgaca atagtgccca
    29761 atatcccttt tttaagttct attttttttc ctaaaatgtt attcatgata ataactccta
    29821 ctattcagtt tttgaagata gagtcagtat acatgaagag ttaaaatagg caatgttttt
    29881 ttatggatat ttgtattgct aaaaatttat cttatatatt cattttgatt atactacttt
    29941 tatttgtaaa aattttctag caaaaccaag tgcttgcaac tgattaagcg tacaattttt
    30001 tagatgttcc gagcgtactt caatcatttc aaaggagttg ctacttaaat cgatattttt
    30061 taaatcagta tcaaaaaagc tagcattttc taaatcatta gtagaaaaca ttattttagt
    30121 gagggaacag tctacaaaat ctgcgcttga taagacagag tgctcaaagg tactttcttt
    30181 tatgtttgaa ccagataaat ttacatagtc cattttacaa ttctcgaata acgtgttccc
    30241 aatataactt tccatcaatt tagtacctgt taatttacaa ttgacaaatt tcacgcgatg
    30301 caacatgctt tttgtcaata tacagcctga aaaatcacag ttttcgaata tacagtcggt
    30361 aatctccatt ctttgaaaat cattggaagc aaaaaatgca tacttgaaaa tagatttgta
    30421 aataattgga tggcagatta tttggttttc gatgacctct ttttgtgaaa ggatattata
    30481 cagttcaaaa tcttcgtttt catagatatg aaaaaaggat cctttattca agcttgcttc
    30541 attaacttta ggaaaaatca tatttaatta cctccatttt cataaagtca tattaacaaa
    30601 agctaaacca acttacatta gcagaaaatg agataggttt tcgccttttt cgataacgat
    30661 agtgtcgcta tctcttgaaa cgttcttaga attgccctga gagacacaaa ttaggcgtaa
    30721 ttctaataaa aatcttagaa taaaaatttt tactgattta atttagaatg tttttaaaat
    30781 aaaaatcgtt gccataacag tgtattgaaa ggttttaaca atccagtaat gatttaaaaa
    30841 aatctagatg tagcgtatac tttgtttata gaatgtagtg ggaagaaata tatttttggg
    30901 aggaaatcgt gatgtctaaa agtgaagaaa tagaaaacat ggtactaaaa ttatatgatc
    30961 tcgttttaaa tccagagatc aaagaaaagg aacgtatact tttgatagac gcaaagacag
    31021 gcttagaaaa aggtcagtat tatcctaaag tcataaataa tttggaacgt agtttacgtc
    31081 cgttagcaat caggggagaa ttgtctaaac cagtatcacc gttttatatg gagatatcaa
    31141 caataggaaa atttgaaaaa gaattaggtc gaggaatggc ttcggcaccg attacttttg
    31201 ggcatttata aaaacgagtt attcatctca atgaattaaa aagtatagtc aatctcataa
    31261 tgcaggctag gttcatttat ttgaacagag tctgtatttt tttattctaa ataaagaaac
    31321 agatgtttct ttatattgta ttttatcctt taattaacac aaaaacagct agtataaact
    31381 aataatgtta attaaaagtg tattttatga aactatcgtt atttattaat gttgcatttt
    31441 tgtaagttaa aaattggaaa tatagattga aaaaatgaaa gcaataagta aaataaaatg
    31501 aatatatgcg aaaaaataat ttacattagg aaaaaccttg taaaaacagt tttttggcat
    31561 atttattttt tataaatatt tgtaaaataa ctatcaattt tttagttaaa agattggaaa
    31621 tgagtggggg aggaattgaa gaaaggattt ttgagagatg atatagtagg ttttattttt
    31681 agttaaaata ggggagatag aaaaaatgaa aaagtgtaga aatattattt tatcaatgtt
    31741 atttattatt actaatataa catcactgat tcctgttcat gtctatgcgg atgcaggcag
    31801 agatatcagc agtaatgtca cttcgttgac cgtggaccca acgaatatta cagatggagg
    31861 aaacataaaa gtaaaattct cgtttgacga aaaaaaacaa aatatccaac caggtgatta
    31921 tctttggatc aattggccaa gtgaaggaaa tattcgcggt gaaggattcc aaaaagaaat
    31981 cccattaatg attgaaaata aaaatgttgg aactttaacg gtcagaaaag attctgcgca
    32041 ggttgtgttt aatgaaaata ttaaaaacct agactcagta gaaggttggg ggcaatttga
    32101 gatacaggcc agaaacgtaa ccgataccgg tgaagaaaat acgggaccat tcaccgtgac
    32161 gagcggtgat aaaacagcta ctgtaaatgt gacaaagcca gcttctggtt cttcttctag
    32221 cgttttttat tataaaacag gagacatgct acctgaagat actaagcaca ttcgatggtt
    32281 tttgaatatt aacaataacg gcacttatgt tgaacaacca gttaaaatca gtgatgaaat
    32341 ccaaagtgga caaagattag atccaagtac gtttgaaatt aatcaaatac acttaggtga
    32401 acagaaggtt tatagaggag aagagggaat ccaacaattt ttacaagatt tccccagcgc
    32461 tacatttaat ttttcagtaa ctgataatta cattgaaata actataccaa aaaactttgt
    32521 caatcttagg aaaataatgg tgagttataa gacgatcata gaaaacccag aacaaataaa
    32581 ttttgagaat cattcggaag cttggtttaa agaatttaat aaacctgctg ttgatggaga
    32641 aagtttcaat catacagtta aaaatatttc agcttctggt ggagtcaacg gtacagttag
    32701 aggcgaattg aagattttca aatatatcaa tgacacagag attggtatcc caaatgtgac
    32761 tttcgaatta agacgagcag atgaacagcc tattcaagga cagtctagta tcctgttgac
    32821 ttcgaatgaa cagggagaag ctagtatcaa aggcctgcaa gtaggagact atgttgtaaa
    32881 agaaaaagaa gcacccaatt ggattgattt tgatccacta agttcaaatg aactcaaatt
    32941 ctccataaac gaaaatgata cagagggagt cagtttacct atttataaca agaaaaaggt
    33001 tacgaacatc acagcaacta aaatttggaa cggtggaacc actccaagac cgagtattta
    33061 ttttaaatta ttcagagcaa gtacaaacaa ttgggaacca gttcctgatg cagaaacaaa
    33121 acgattagac aatggaataa cttcagtgac ttgggaagat atccaacagt atgatgatag
    33181 tggaaacgaa tatacgttta aagtgcaaga agtagatcaa aacggaaatg attatgtccc
    33241 ttcaggttat caaaaaattg aaaacgggct agtcgttaca aatgagaata aagaagtcat
    33301 ttcagtctca ggacaaaaaa catgggaaga caatgagaac caagacggca aacgaccgac
    33361 gacgatcaca gtaaatctat tagccgacgg tcaaccgatc caacacaaag aagtaagtga
    33421 aaaagatgat tggcgctatc gtttcacaaa tctgccaaaa tacagagacg ggcaagaaat
    33481 catctatact gtaacggaag acaacgtgcc cgaatacagt acgacgattg acgggtataa
    33541 catcaaaaac agttatacac cggaaaaaac aaatatatct ataccaggta gccatataac
    33601 accgtggaaa aattttccag agaagacaga gagagagaaa attagaaatc tattctctca
    33661 aaaattgcaa atatttgctc atacaggaga atccagcgaa caaagaagca attatattag
    33721 taagagagct gtacctaaac agataacaaa taaatcaaaa agcattcttc ctaaaacaag
    33781 tagtaaaaaa tctagttttg ctgtaatcat tggtttattg atagtaacta tctgtgctgg
    33841 gatattctta caaaaatata aaaaagttta gttagaatat aatatttttt gttaaatatg
    33901 actgaaatca aaagaataaa attccgattt ataatcgaaa aaagaagcat ttttatatat
    33961 gcttcttttt tcgtagaatc aataaatatg gatttggcta actatggaag aatactcgta
    34021 ttagttttca gcgttcatac tagttgttac attgtttgat tggccaaaag aatttctgat
    34081 atattttgtg ctaaataaag aaaaagacgc ttgaattggg aaataagaaa actactctat
    34141 cattacaaat tttcataaac tggcagatgt tctaagtaaa caagtatctt ttcaaagtcg
    34201 gaaaaatcca taatcaacgt agtggtattg atatttggat gaaagcctac ggtatcttga
    34261 cgatcaatag cagcatcgat cacgacttgg atttttttct ctttgtcgtg catcaatgct
    34321 aatggagtca ctgtacctgc tggaacgcct aggaggtcag gaagctgttc ttcagaaaca
    34381 aaagataagc gcttttcttt taattgttca gctagttgtt ttaaatcggc gtgcttttca
    34441 tcaggcaaga tgacaagata gatttgtttt ccttttcttg atttcaataa tagatttttt
    34501 acttgcggac caggtaggga aaaagggaca tttttgactg acgtaatcgc aggatgatcg
    34561 actttttgaa aagagatacc cagttttttt agtagttcat aagcttcttg ttcggttgca
    34621 cgactcatcg cgcatcaccc tccttttttt attagtgtat cataaaaaag agttgacaaa
    34681 tgaaaaataa tcatgtaaat tacacgtaaa gttaaaacaa atgacatcga aaagaagagt
    34741 agccgttagg tgtttttaga gagtctctgg ttggtggaaa gaggcagcag ttaaccgtga
    34801 aacacatctt ggagtcgatt ttctgaagcg tatagtagga aaatccgggg agcccgttac
    34861 agctgcggtc gttgctagat gaccagataa ggctggcttt tccgtgagga gtcggtaaaa
    34921 aaaggtggaa ccacgtgatt aacgtccttt gatcttcgga tcaaaggact ttttgttttc
    34981 atctgaacgg caacgactgt gtgaggtttt ttctgcaagg aaaaaataaa cagaggtgga
    35041 accacgtata atacgtcctc ttggcatttg ccaagaggat ttttttattt taaaggagga
    35101 aaagaagatg gagtatttga ttgaagttat gccgcaatta ttagtaggag cactcacaac
    35161 attgaaatta tttttattta ccttgattgg ctcattacca ttagggattg ttttagcatt
    35221 aggattgtct ttgcatttta agccgctacg ctacttgctt caaacatatg tatgggttat
    35281 gcggggaaca ccgctgttgt tgcaactgat ttttattttt tatgggttgc cgacgattgg
    35341 gatcgttttt gatcgtttcg aagcagcact cattgccttt atcttaaact atgcagctta
    35401 ttttgcagag atctttcgtg gagggataca atcgattcct caaggtcaat atgaagcagc
    35461 gcaagttttg caattaagtc cctttcaaac ggtgacgaaa atcgtcatcc cacaagtgac
    35521 aaagattgtt ttaccttctg tagggaatga agttatcaac ttggtcaaag attcttcctt
    35581 gatctatata ttaggtttag gtgacgtaat gcgtgctggg aaaatcgcga tggaacgcga
    35641 cgcgacttta ctgcctttgc taggcgtggc aatcatctat cttacattga ctggtattct
    35701 aacaatcgta atgaaacaag ttgaaggaaa attaaattat taccgctaac tgataggagg
    35761 aagaaatatg attgaattga agaaagtgaa caaagcattt ggtgaaaaaa aaataatcaa
    35821 agatttgaat ctaatcattc cagatgggaa aacattagct atcgtaggtc cttccggtgg
    35881 cggtaaaacc acgcttttac gtatcttggc tggcttagaa agttctgaca gcggagaatt
    35941 ttatttagac ggtgtaccgt tcaacccatt cgagcttaaa atgaaagaac aagttgtagg
    36001 agtcgtattc caagacttcc agctatttcc acatctgaat atttttgaaa acattacctt
    36061 agcaccaaaa atggtattga aacagacaaa agaagaatac accaaaaaag cagaagaatt
    36121 agcggcttca ttagggatta gtgatttatt gaatatctat ccttatcagc tttctggcgg
    36181 acaaaaacag cgggtagcga ttgccagagc attggctatg aatccacggg tattggctta
    36241 tgatgaacca acaagtgctt tagatcctga attacgccag caagtcgagc gtttgatcct
    36301 atcattgaaa gaagatgggg taacccaaat tattgtcacc catgatttag tatttgcaga
    36361 aaatgtcggt gatcaattac taaaagtttc cccaattcat taagaaagga gaagatagag
    36421 atgaaaaaaa ccagttttct attcgctttg atcgcaggtc ttcttctttt tgcaggctgt
    36481 tcgaacaaaa aaacttcagc agataattgg gcgactatca acgaagagaa aaaaatcgtt
    36541 ataggtttag acgatacatt tgttcctatg ggatttagag ataaagacgg gaagctcaca
    36601 ggatttgata ttgatttagc caaagcagtc tttgaacaat atgggattac ggtagacttt
    36661 cagcccattg actggtcaat gaaggaattt gaactgaaca atggaacgat cgatttgata
    36721 tggaacggct attccaaaac gccggcaaga gaaaagaaag tgcaatttac aaaaccttat
    36781 atggaaaacg atcaagtgct gatcacacct aaagaatcag gaatcacaaa ctttggacaa
    36841 atgaataata agagattagg tgcgcaaaat gggtcatctg gttatgatgt atttacgaaa
    36901 caaccagaag tattaaaaga gatagtcaaa aaccaagatg ctgttttgta tgatagtttt
    36961 aatgaagcat tgatcgatct gaaaagcaga cgggtcgatg gtctgctgat ggataaagta
    37021 tacgcagact attatttgaa acaaagaaac gaactagaag acttcaacat aacaaaaggt
    37081 tcttatgaga gtgaggattt tgcagttggt gcacgcaagt cagatagtac attagtgaaa
    37141 aaaatcaatg aagccctaga tcaactagag aaaacaggtg aattccaaaa aatatccgat
    37201 aaatggtttg gcgaagatgt tacgccgaga aattaacaaa taggggactg tgacaaaaga
    37261 cgtgtcacag tccctttttc cgaataaaca gtgttctcct gccaactcct tgtgactcgg
    37321 agctgaatgg caggctcaca acctcttggt aaacggtgtt caaaagccag tttttcggta
    37381 ttaagccaaa tttatgcaaa aatgtagaaa gccattttca caaaattttt cttactactc
    37441 gaaactaagc gactttttca caacctcctt tacatatttt tattttgttg tggaaggggt
    37501 ttcgtgttat tctaaaagag gaacgattga aggttatagg aaaggaagag atgaatggaa
    37561 cacaaagaac ttacctcatt tccaaaagat tttctgtggg gctctgcttc tgcagcgtat
    37621 caagtagaag gagcttggca agaagatggg aaaggagaat cagtctggga tcgatttgta
    37681 cggatacctg gaaagacatt taaaggaacg aacggtgatt tggcagtaga ccactatcat
    37741 cgttataaag aagatattgc tttaatgaaa gaacaaggtc tgaaagctta ccgcttctct
    37801 gtagcttgga cacggatttt tcctaatgga cgaggagaag tcaatcaagc tgggctcgct
    37861 ttttatgaga gattgatcga cgaattgatt gaaaacgata ttgaacctat gttgacttta
    37921 tatcattggg atcttccaca agcattgcaa gatgaatata atggttggga atcacgtcag
    37981 atcattgaag atttcactca ttatgcagaa acattatttg aggcattccg cgggaaagtc
    38041 cattactgga ttagtttgaa tgaacaaaat atcttcactt cattaggtta tttgttagca
    38101 gcacatccgc caggtgtgac agacccgaaa cgaatgtatg aagttaacca tattgctaat
    38161 ttagcaaatg catctgtcat caataaattt cacgagttag aaatgcctgg aaaaatcgga
    38221 ccaagctttg cgtatacgcc aaattatcca attgacagta atcctgaaaa tgttctggct
    38281 gctgaaaatg cagaagacct gatggccaat tattggatgg atgtctatat gtggggaaaa
    38341 tatccgattg ctgccatgag gttcttagaa gaaaaaggat gggcaccaac gattgaagct
    38401 ggcgatgcag aattgctaga atctgctaaa ccagattttc ttgggatcaa ttactatcaa
    38461 acggcgacga atgcattcaa tccattaaac ggagttggtg ctggaaaaat gaatacgaca
    38521 ggaaaaaaag gttcatcaga agaaactgga gttcctggaa tgtataaaaa agttgagaat
    38581 ccatttgtcg aacgaacaaa ttgggactgg gagattgacc cagaaggatt aaggatcgga
    38641 ctgcgtcgta tcacaagccg ttaccgcatg ccggtactga ttacggaaaa tggcttagga
    38701 gagtatgaca agttgacaga agataaacaa atccatgacg actatcgaat caattactta
    38761 caaagccacg tcaaagccat caaagaagca atttcggatg gagcagaagt cctaggctat
    38821 tgcacctggt cttatacaga tttgcttagc tggctgaacg gttatcaaaa gcgatatgga
    38881 tttgtatatg ttgatcaaga cgaaacacaa gaaggatctt tggaacgata taagaaagac
    38941 agttattact ggtaccaaaa actgattgaa gaaaatggag agaaccttta gttcacatac
    39001 ttaaaacaag aaggtacggc tggatatggc cgtgcctttt cttgataaaa tcatttagaa
    39061 attaagaaaa actgtaaaat aagctgaaaa atgaaagaaa gcgtcagttc tttcaaacaa
    39121 aactttagtt cccttacttt tttttgtata atgaaacttg atgaaatgag ggataataaa
    39181 tggcacaaaa gaaacggcct actaaaaaaa ggaaaaagac gaaaaaaacg aaaaagcaaa
    39241 aacagcagca ggaacaaatg ctgacgattg gtgttgggtt tgccttgatt ttatttgctg
    39301 tcttcggctt tttaaaatta ggttttttag gaatattgat tgcaaacggc tttcggatca
    39361 ttgcaggaaa tacttaccaa atcctctgtc ttttattagc cgtattagga ttttggattg
    39421 tcattaagaa tacagagttt tcaattggta aaaaccgacg ctggtttggc ggcatactct
    39481 tttatttcgg tatcttatta ttgttacatg cccatttatt tggcaaactc catactgggg
    39541 aaccaaatat catggggacg acatgggatt tgttagccag tgatataaaa caaagtcaag
    39601 tagacaataa cgttggtggt gggatgattg gagcaatcct ttatcatttt acttacttct
    39661 tgattgcaca gcctggaagt tatttagcag cagtgctatt actggcagga ggagcattcc
    39721 tgttcagtaa tctggaaggc tatcagctgt taaatggtat ccaatcaatt ggagaacgag
    39781 tacaggaatt attggaaggt gatcctgcca agcaagctcg aaagcaagcg gcaaaggaag
    39841 agagaatgaa acagcgcgca gaagcgaaag aagcaaggcg cttagctgca aaagaagctg
    39901 cagaaaaaga agctgcagaa tatgagaaga aaaaagcggt gagccagcaa agggaaaata
    39961 ctgctgatga atggcaggaa ccagaaaata cagagccgga gcagctaagt tttgttccaa
    40021 tcgacagttt tcaagaaaat atccatcctg cgaatctaga gaaaccagta ccagatacac
    40081 caaaacagac caatacagca gaaggttttt cagatgagtt gccagaggat gacggtacct
    40141 cattagaatt tgagattgaa gcagaacagg aaaatcaaga ctatgaatta ccgacagttg
    40201 atttgcttga ttctatacca actgtggatc aaagtgatga gtataaaaaa attgaaaaaa
    40261 atatcggcgt attagaacaa actttccaaa gtttcggtgt cgatgccaag gtcgtcaaag
    40321 ccagcttagg accatccgtc acaaaattcg aagtccagcc ggctgtaggg gtaaaagtaa
    40381 gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt agcggcgaaa gatgtccgga
    40441 tggaagcacc gattccaggt aaatcactga ttggtattga agtaccaaat ggaaagatca
    40501 gtatggtttc ctttagagaa atcatcgaag cacaaccaaa ccacccagat aaattactag
    40561 aagtaccttt aggacgtgat gtttctggac gggtacaaac ggctgatctt tcgaagatgc
    40621 ctcacttact cgtggctggt tcgactggta gtgggaagtc agtagcaatt aatgggatta
    40681 tcacaagtat attaatgcgt gctaagcccc atgaagtaaa actgatgatg atcgatccga
    40741 aaatggttga attgaatatg tacaacggca tacctcatct gttgacgccg gtcgtgacga
    40801 accctagaaa agcagcgcaa gccttacaaa aagtagtaca agaaatggaa gaacgatatg
    40861 aaaaattcgc ggcaaccgga gtaagaaata tttctggtta caatgaattt gttcaacaga
    40921 aaaacttgga aaacggaacg aaacatccaa ccttaccatt catcgtagtg atcgtagatg
    40981 aattagctga tttgatgatg gtagccagca atgaagttga agatgcgatt attcgtttag
    41041 cgcaaatggc tcgggcagcg gggattcata tgatcctagc tactcaacgt ccaagtgtgg
    41101 atgttatcac aggaatcatc aaagcaaatg taccttccag aatggcattt gcggtatcaa
    41161 gcggtacaga ttctcggacg atcattgatt ctaatggggc agaaaagctc ttagggcgag
    41221 gagatatgct attcttgcca atgggtgaga ataaaccgat ccgtgtgcaa ggagcattca
    41281 tttctgacca cgaagtagaa cgggtcgttc aatttgttac agatcagcaa gaagctcatt
    41341 atgaagagaa aatgatgccg acagatgaag ttgaaacgac aggtgctcca gaacagccac
    41401 aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga aatgcaaacg gcaagtattt
    41461 cccttctcca aagaagattt cggatcggtt acaaccgagc agcacgttta gtagatgaac
    41521 tggaagctca tggagttgtt ggcccgtcag aaggaagcaa gcctcggaaa gtattcattg
    41581 agcaggaaga aacatcagaa acgttgccgg acgataatga catgtaaaac ttgtgtgatg
    41641 aagggttgaa aaacgaataa ccaataaaaa gacaaggcat gatgatacca aaagaaaaaa
    41701 tggttttttt ccatcttttc taatacggta tgatgtcttg tctttttagt ttttgtgaga
    41761 ttaaagttct attcgattta tttgtgaagt attgcattaa ggaaatgaat catgtatagt
    41821 atgtagcgaa actttgagaa aaagagggaa aatactttgg aaaaacagtc catttatggc
    41881 ttgacgaatg aagaattaat caattggttt atagaaaacg gcgagaaaaa attccgagct
    41941 gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat
    42001 ctatcgaaac aattgatcga aaaattatcg gagcatttta tcatcaatcc tctaaaacag
    42061 atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt tgtttgaact ccctgataaa
    42121 aacatgattg agactgtact gatgagacaa gaatatggct tgtcagtttg tgtgacgaca
    42181 caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt
    42241 gatctgactg ctggagaaat tgttgcacag atcatgatgg tccaacatta ttttgatgag
    42301 cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg ggatcggtga gccatttgat
    42361 aattacgaca atgtaatgga ctttttgcat atcatcaatg atgccaaagg attggcaatt
    42421 ggtgctcggc acattacagt ttccactagt ggattagcac acaaaatcaa ggaattcgct
    42481 aataacggct tgcaagtcaa tctggctatt tccttgcacg cgccgaataa tgaggtgcga
    42541 acatcgatca tgcggatcaa ccgaagtttc ccaattgaga aattgatgga agctgtggat
    42601 gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta
    42661 aatgatagac cagagcatgc gcaacaatta gcagatctat taaaagataa gaaaaaatta
    42721 gcatatgtca acttgattcc atataatcca gtcagtgaac atgatcaata ttctcgcagt
    42781 ccaaaagctg atgtattgag attttatgat gtattgaaga aaaacggcgt aaactgtgtg
    42841 atacgtaaag aacatggtac agatattgat gcagcttgcg gacaattgcg aagcaagcaa
    42901 atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt ttttcaatta ccataaaagg
    42961 agcagttttc ttaattaagg aactgttcaa cttaaataag agaaaagatt ctatagcgaa
    43021 agctataaag ctttttttga caagaaaaac cctcatcaag caaagaaatg tcctcaattt
    43081 gatgacagcc tgcttgatgg gggttttagc aattatttaa ctgattttct tatatccttg
    43141 ctggctttct tgtgtagcat gataagtttc tacgtcaaga atggcctgtt taaatttttc
    43201 tcgggtgatt tcataaggca catgtttaat atcatttgtt gccatggctt tatctaagat
    43261 tgcttctaaa tcggtcgtga cattgagatt catgtcggtt aacgatactg gaagttggtt
    43321 ctttttcata aacacataga ttttatcaaa caaatcgaac tgctgatcca tcatcaataa
    43381 ggtcagtaca ccataactga cagatgctcc gtgaaggtat ccctccattt tttctagaac
    43441 agtcgtaccg taatagaatg agtgtgccat agcagaatta tagttattgt taactaaaac
    43501 agaaaccaat ccggtagtaa caatgatatc cgaaacgact tgttcaattg catatgaggg
    43561 acgatcgtcg gcactatctt tcaatgcttg cgtaccataa gtcaagagac gatcaatgca
    43621 catttttccg atttggattc ctaatctatc cgtgtagcct agatcatcgc cacgagcaga
    43681 aaaagtagat tcgacttctt tggataaagc atcgccaata cctgcccata agtatttatc
    43741 aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt acaggtggtt ttgaaggaaa
    43801 gaagagtccg tccattacgc cttcttcgtt atagatgaca cataccgcag tgacgggcga
    43861 acagttcgaa ccaatagtgg gaaaggtgaa gactggttta gctagttttt caccaatgac
    43921 ttttacagta tcgcaagcac ggccaccacc gactgcaaac aggacgtctg ctttttggac
    43981 actttcatgc tggatcaact gttcaatatt tccataagtt gaattacccc cgtaccagag
    44041 actggcgaca acctctattt cctgtgtcaa agctactttt attttgtttt ctgcctttga
    44101 aagtgcagtc ttccctccaa tcagcactac ttttgtccca tattctttga cgattccatt
    44161 tgctttttca tacgcatctg ttccaatggt ataatttggt aagaaaacac tttgactcat
    44221 attcatttcc ttctttcttc gttgaaacgg gttaaaattt taaagagtga tcgatctgac
    44281 tgcggctgta gatggagtag aggtgaacct aagacaggat aagtgatgaa taaggtggca
    44341 tgaacacctt gaaatcatca ataagtatcc taaaaacgaa caagtacaaa aacattgaaa
    44401 acgacaataa tgaatttttg ttcctcttag tatttctacc gattcccttt gcttttttgt
    44461 aattatctaa aaattctaaa aattaagatt attatatgaa aacaggtttt atttgtcaat
    44521 tcataattgg ttttttttaa agcaaaagat aatctatatc atgatgaaca aacagagttt
    44581 tttcctccaa ttgatggctt tcctgatctt tcctattttg aataaagtgt ttctgtataa
    44641 tttttttatt ttataagtaa gataaataat gaaagaatag agatactgat tggtagctaa
    44701 agatttttga gcgagaacat ttcgtttttt caaaaggact gttagaataa gcaagaacaa
    44761 gggggaagac gtatgataat cagtgaattt gaccgtaata atccagtatt gaaagatcag
    44821 ctttctgatt tactgagact gacttggccg gaagaatatg gagacagctc ggcagaagaa
    44881 gtagaagaaa tgatgaatcc agaacgaatc gcggtagcag cggtagacca agatgagtta
    44941 gtaggattta ttggtgcaat ccctcaatac ggtatcacag gttgggaatt gcatccatta
    45001 gttgtagaaa gctcccgacg aaagaaccaa ataggtactc gattagtcaa ttacttagaa
    45061 aaagaagtag cttccagagg aggaatcacg atttatttag gtacggatga tttagaccat
    45121 ggaacaacgt taagtcaaac ggacctgtat gagcatacat ttgataaagt ggcttccatc
    45181 cagaaccttc gtgaacatcc gtatgaattc tatgaaaaat taggttataa aatcgtaggt
    45241 gtcttaccaa atgcaaatgg ctgggacaaa ccggatattt ggatggcaaa aacgattatt
    45301 cctcgaccaa attctcaata ataaaaagag gttgtgacag aagtaatcag cttcaagaaa
    45361 taagaaggaa tttacgaaaa ttacttcttg aatttttgtg aaattccaac ttatttccga
    45421 agaagctact tttggaacac cgtgtac
//
LOCUS       DAYYEF010000018        44026 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000018 DAYYEF010000000
VERSION     DAYYEF010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.018"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..971)
                     /locus_tag="ACHA1B_001157"
     CDS             complement(<1..971)
                     /locus_tag="ACHA1B_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TGS domain-containing protein"
                     /protein_id="HFM8701935.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMG"
     gene            complement(1308..1487)
                     /locus_tag="ACHA1B_001158"
     CDS             complement(1308..1487)
                     /locus_tag="ACHA1B_001158"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016862 - intramolecular oxidoreductase
                     activity, interconverting keto- and enol-groups [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxymuconate tautomerase"
                     /protein_id="HFM8701936.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(1534..3357)
                     /locus_tag="ACHA1B_001159"
     CDS             complement(1534..3357)
                     /locus_tag="ACHA1B_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFM8701937.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            3635..5914
                     /gene="helD"
                     /locus_tag="ACHA1B_001160"
     CDS             3635..5914
                     /gene="helD"
                     /locus_tag="ACHA1B_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase recycling motor HelD"
                     /protein_id="HFM8701938.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(6007..6654)
                     /locus_tag="ACHA1B_001161"
     CDS             complement(6007..6654)
                     /locus_tag="ACHA1B_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701939.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(6833..7552)
                     /locus_tag="ACHA1B_001162"
     CDS             complement(6833..7552)
                     /locus_tag="ACHA1B_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8701940.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(7683..8834)
                     /locus_tag="ACHA1B_001163"
     CDS             complement(7683..8834)
                     /locus_tag="ACHA1B_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HFM8701941.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(9051..9791)
                     /locus_tag="ACHA1B_001164"
     CDS             complement(9051..9791)
                     /locus_tag="ACHA1B_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM8701942.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(9795..10118)
                     /gene="rsfS"
                     /locus_tag="ACHA1B_001165"
     CDS             complement(9795..10118)
                     /gene="rsfS"
                     /locus_tag="ACHA1B_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HFM8701943.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(10175..10768)
                     /gene="yqeK"
                     /locus_tag="ACHA1B_001166"
     CDS             complement(10175..10768)
                     /gene="yqeK"
                     /locus_tag="ACHA1B_001166"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HFM8701944.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(10752..11402)
                     /locus_tag="ACHA1B_001167"
     CDS             complement(10752..11402)
                     /locus_tag="ACHA1B_001167"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HFM8701945.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(11412..11723)
                     /gene="yhbY"
                     /locus_tag="ACHA1B_001168"
     CDS             complement(11412..11723)
                     /gene="yhbY"
                     /locus_tag="ACHA1B_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HFM8701946.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(11739..12848)
                     /gene="yqeH"
                     /locus_tag="ACHA1B_001169"
     CDS             complement(11739..12848)
                     /gene="yqeH"
                     /locus_tag="ACHA1B_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HFM8701947.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(12845..13372)
                     /locus_tag="ACHA1B_001170"
     CDS             complement(12845..13372)
                     /locus_tag="ACHA1B_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HFM8701948.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(13552..14337)
                     /locus_tag="ACHA1B_001171"
     CDS             complement(13552..14337)
                     /locus_tag="ACHA1B_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HFM8701949.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(14330..15199)
                     /gene="accD"
                     /locus_tag="ACHA1B_001172"
     CDS             complement(14330..15199)
                     /gene="accD"
                     /locus_tag="ACHA1B_001172"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HFM8701950.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(15200..16579)
                     /locus_tag="ACHA1B_001173"
     CDS             complement(15200..16579)
                     /locus_tag="ACHA1B_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HFM8701951.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(16587..17006)
                     /gene="fabZ"
                     /locus_tag="ACHA1B_001174"
     CDS             complement(16587..17006)
                     /gene="fabZ"
                     /locus_tag="ACHA1B_001174"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFM8701952.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(17031..17507)
                     /gene="accB"
                     /locus_tag="ACHA1B_001175"
     CDS             complement(17031..17507)
                     /gene="accB"
                     /locus_tag="ACHA1B_001175"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA];
                     GO_function: GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HFM8701953.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(17510..18745)
                     /gene="fabF"
                     /locus_tag="ACHA1B_001176"
     CDS             complement(17510..18745)
                     /gene="fabF"
                     /locus_tag="ACHA1B_001176"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HFM8701954.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(18764..19501)
                     /gene="fabG"
                     /locus_tag="ACHA1B_001177"
     CDS             complement(18764..19501)
                     /gene="fabG"
                     /locus_tag="ACHA1B_001177"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004316 - 3-oxoacyl-[acyl-carrier-protein]
                     reductase (NADPH) activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HFM8701955.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(19513..20430)
                     /gene="fabD"
                     /locus_tag="ACHA1B_001178"
     CDS             complement(19513..20430)
                     /gene="fabD"
                     /locus_tag="ACHA1B_001178"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HFM8701956.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(20537..20761)
                     /locus_tag="ACHA1B_001179"
     CDS             complement(20537..20761)
                     /locus_tag="ACHA1B_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000035 - acyl binding [Evidence IEA];
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFM8701957.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(20814..21776)
                     /locus_tag="ACHA1B_001180"
     CDS             complement(20814..21776)
                     /locus_tag="ACHA1B_001180"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HFM8701958.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(21786..22226)
                     /locus_tag="ACHA1B_001181"
     CDS             complement(21786..22226)
                     /locus_tag="ACHA1B_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFM8701959.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            22532..23497
                     /locus_tag="ACHA1B_001182"
     CDS             22532..23497
                     /locus_tag="ACHA1B_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HFM8701960.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(23554..23784)
                     /locus_tag="ACHA1B_001183"
     CDS             complement(23554..23784)
                     /locus_tag="ACHA1B_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HFM8701961.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(23870..24757)
                     /locus_tag="ACHA1B_001184"
     CDS             complement(23870..24757)
                     /locus_tag="ACHA1B_001184"
                     /EC_number="1.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFM8701962.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(24846..26069)
                     /locus_tag="ACHA1B_001185"
     CDS             complement(24846..26069)
                     /locus_tag="ACHA1B_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFM8701963.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(26086..27132)
                     /locus_tag="ACHA1B_001186"
     CDS             complement(26086..27132)
                     /locus_tag="ACHA1B_001186"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HFM8701964.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(27296..29023)
                     /gene="ptsP"
                     /locus_tag="ACHA1B_001187"
     CDS             complement(27296..29023)
                     /gene="ptsP"
                     /locus_tag="ACHA1B_001187"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008965 - phosphoenolpyruvate-protein
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HFM8701965.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(29023..29289)
                     /locus_tag="ACHA1B_001188"
     CDS             complement(29023..29289)
                     /locus_tag="ACHA1B_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HFM8701966.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            29768..32002
                     /locus_tag="ACHA1B_001189"
     CDS             29768..32002
                     /locus_tag="ACHA1B_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM8701967.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            32150..32470
                     /locus_tag="ACHA1B_001190"
     CDS             32150..32470
                     /locus_tag="ACHA1B_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFM8701968.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(32675..32899)
                     /locus_tag="ACHA1B_001191"
     CDS             complement(32675..32899)
                     /locus_tag="ACHA1B_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HFM8701969.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(33097..34677)
                     /locus_tag="ACHA1B_001192"
     CDS             complement(33097..34677)
                     /locus_tag="ACHA1B_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_process: GO:0006415 - translational termination
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HFM8701970.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(35078..36454)
                     /locus_tag="ACHA1B_001193"
     CDS             complement(35078..36454)
                     /locus_tag="ACHA1B_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFM8701971.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(36582..37670)
                     /locus_tag="ACHA1B_001194"
     CDS             complement(36582..37670)
                     /locus_tag="ACHA1B_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFM8701972.1"
                     /translation="MFWSLELLIIAALIMISSEINFIFEPIGTFFSTLFAPVLIAGFL
                     YYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQISSLASNMPDF
                     IKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSLGSIVGTIASA
                     TVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTLANYISGQAIE
                     CLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLVTVFNDPVKAL
                     LCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLGIFLGVPFYAI
                     CKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            37842..38276
                     /locus_tag="ACHA1B_001195"
     CDS             37842..38276
                     /locus_tag="ACHA1B_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8701973.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(38354..38887)
                     /locus_tag="ACHA1B_001196"
     CDS             complement(38354..38887)
                     /locus_tag="ACHA1B_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HFM8701974.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(38981..40159)
                     /gene="mutY"
                     /locus_tag="ACHA1B_001197"
     CDS             complement(38981..40159)
                     /gene="mutY"
                     /locus_tag="ACHA1B_001197"
                     /EC_number="3.2.2.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA];
                     GO_process: GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HFM8701975.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(40152..40949)
                     /gene="recX"
                     /locus_tag="ACHA1B_001198"
     CDS             complement(40152..40949)
                     /gene="recX"
                     /locus_tag="ACHA1B_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HFM8701976.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            41056..42438
                     /gene="rlmD"
                     /locus_tag="ACHA1B_001199"
     CDS             41056..42438
                     /gene="rlmD"
                     /locus_tag="ACHA1B_001199"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HFM8701977.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(42612..43190)
                     /locus_tag="ACHA1B_001200"
     CDS             complement(42612..43190)
                     /locus_tag="ACHA1B_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HFM8701978.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            43512..43982
                     /locus_tag="ACHA1B_001201"
     CDS             43512..43982
                     /locus_tag="ACHA1B_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TspO/MBR family protein"
                     /protein_id="HFM8701979.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
BASE COUNT        12583 a         9355 c         7653 g        14435 t
ORIGIN      
        1 tctcccatat ccattggcgg gaacatgtct tcttgataat gatcccagtg tccagatgtt
       61 ttgtacaact caacatctcc cattattggt gtatatacat gttggtaacc tagactaact
      121 tctttgtcta cgatataacg ttcgatcgtg cgtcggattg ttgccccttt tggaagccag
      181 aatggcaaac cagaacctac ttctggggaa accatgaaca agtcaagttc ttttcctagt
      241 ttacgatggt ctctttcttt tgcttcttca cggagacgga tatattcttt caaagctttc
      301 ttgtcaaaaa aggctgtccc gtatacacgt tgcatcattt gattgtttga gtttccacgc
      361 caataagcac ctgccactga taataattta aatacttgta tacggccagt ggatggaaca
      421 tgtggtccac gacacaaatc gatgaattcg ccttgttgat aagcagtaat cacttcttct
      481 tctggcaatt cactaatcag ttctactttg tacggatcac ttgcaaaaat ttctaatgct
      541 tcctgttttg aaagaacacg gcgttcgatc ggcagatttt ctttgacgat tttcatcatt
      601 tctgcttcga ttgccggcaa atcttctgca gttacttggt tttgtccatt atctgtatcg
      661 tagtaaaacc ctgaatcgat agctggtcca acgccaaagt ggatatttgg atagaggcga
      721 cgcatggctt gggccatcaa atgagctgct gaatgacgga ctaagccaag tgcatcttca
      781 tggtctggtg tgatgatctc aatacttgca tcttcctcga ttggacgagt caaatcaacg
      841 agttttccgt tcactttacc agctaaagct ttttttgcta agctttttga aatgctttca
      901 gcaattgcca atgttgttgt tccagactca aattctttga ctgcaccatc tggaaaagta
      961 atttttatca taatagtttc ctccttgaaa tgttttgatt gatcagatca tcaagctgaa
     1021 aaacaaaaaa atcctagcat ctcttgaaaa gagatactag gacgaaaagt tcgtggttcc
     1081 acctaatgtt caaacgcaaa tgcgttcctc aagcgttgta acggtccgac cgcccttgct
     1141 tcaacaaggg tttcgaaagt ggtcatcctt tggttttctc ctggaaaagt ttcagcctag
     1201 cttttcctct cttatcgaag actctcaaat tcagttggct ttctcatcaa tcaattatgt
     1261 gtttatttaa ccactaataa atagaaaaat caagtgggaa actaaactta ttttttccat
     1321 tccccattta caccgtatgt tccttttttc atctcattga tgatgacatg gatgtgttct
     1381 tttggtgcct gcgtgttttt atgaacagct tccgtgatat ctttcatcat attttctaat
     1441 tgttccggac tgcgaccttc tactaattcg acatgtacga atggcataat gctctctcct
     1501 ctttctgatc gttctttttt caactcgatt ctatcatact atgtttgtct tgggtactga
     1561 atcaggaaaa atggctggat ctttttttgc tctcaaggca ctcaaaatag agaccgtatc
     1621 cacgacttct tgcaaaacag ctccgaataa tgcggggatt agtcccgtac ttgcaattaa
     1681 catcaaaaaa atacaaataa agatgccaat cagtacagac tgtttcgcta ttctcatcgt
     1741 atctcttgaa atcactactg cttttgctac acgcaagaga tcatctttca agatgaccgc
     1801 atctgcactt tcactagcag ctgtagaacc atgagccccc attgcaatac cgatatctgc
     1861 agcagcaagt gctggtgcgt cattcacgcc gtctcctacc atcgcaacag gtctttgatc
     1921 tttagggata ctttctaaaa tggtcagttt atcttgaggc aagctacggg catgtacaga
     1981 atctaattgg actttttctg caatcgtttg agcaatggca gatccatccc cggtgatcat
     2041 catcaaattt ttcacatcaa gttttcttag ctccttgatt gtctttgctg cttctgggcg
     2101 aatctgatcc gaaaatagga tcgttcctgc aaaagatcga tcaattgtta catagattgc
     2161 tgtattggac gtttctattt cttcagctga aacaaaagag gcacgtccaa tctttacttc
     2221 atgattattg actactgctt ggattccttg accggtcact tctttcagtt gactaacagg
     2281 atacagttgg ctgtttttca cgttgttcac taacgaacga gctaagatat ggctagattc
     2341 ctgttctgca ctagctgcat acagaagtag ctcttctttt tttattccat tgactggctg
     2401 aatcgcctct acttccaata tccctttggt aagcgttcct gttttatcaa aagcaatcgt
     2461 ttttgtacgt gcgagctttt caatcgttgt tccagttttt acaacgatcc cgtttttact
     2521 tgaacggctc attcctgcaa ctaaagcaat gggcgcagct agaatcagtg gacaaggtga
     2581 tgccactacc agtacctcag caaatcgtaa agggtctttt gagaaccacc aagaaatacc
     2641 accgatcaaa taagcaatca acgtgaaagg gactgcataa cgatcagcta aacggacaaa
     2701 tcgggcaggc ttttcttttg attcttcgac tagtttaata atcatttgat actggctgtc
     2761 tgcggcacgt ttttcagcga tcatttggat cgatccgtct ccatttaaag accctgacat
     2821 aatctgatct ccaggtttct tggtttccgg gcgggactca cctgtcaaag aagattcatc
     2881 gaccgaagat tctcctttgg tcactcgacc atctgcgggt acaagttcgc caggcttgac
     2941 tagtaactgg tcatcaatat ttatttcatc gattactata tcctgcaatt ttccttcttt
     3001 gaatcgatgg gcaattcttg gggtgttatc taacaaagac tgcagttctt tacccgctcg
     3061 tttattcgcg taatcctcta gactatctcc gcccgtaagc atgatcaata tcatcaaact
     3121 agcccagtat tctttgacgg ctaatgttgc aaggattgcg gtaatcgcta atacatctac
     3181 gccatatctt cctgaacgta acgtcttgat catttccaaa aacatcaaga aggcgagaat
     3241 ccctccagta aatgcgacaa tcgcaaatgc aagggccggc tggtgaaaaa caaattcact
     3301 taataaagct atcccaccaa taagcaaagt aagtaaaaat tttttgaaat gtgtcattgt
     3361 tttttctcct cttttatgtg acttagagag gttagtaata aatttccagc tgcctctttc
     3421 atcttaagca tagtccttga ctagcacttt ttaaaacaat aggccttaat tgaaaacaac
     3481 tatcactatc agcgtttcca aaattcatca gttctacaaa caaaaatatt cagcaaggat
     3541 tactttttcg attcatcagt taaaaagtac cttttttcga aaaactatgc tatactttta
     3601 attcgttatt tacggcggaa ggagcaaaca tgcgatgaat gagaaacaac tagaacaaac
     3661 gcacgtggat gaaacgatcg aactaatcca gatcgaacaa aatatgctgg atacaaaaca
     3721 acaagaattg actcaggaaa tgaatcattc gacaaaagac acagctaatc acaagattcg
     3781 agctggttcc aatgaagctt tttatgaatc tgctgttgaa tatcgccaac atgagcagga
     3841 attgcttttg aaataccata ctcttgaagc acagcaaaaa cgcctgcaaa cgttgtctgt
     3901 catgaaagat agtccttatt ttgcccgtat cgactttaaa gaagaccgtg aaacagaaac
     3961 attatatcta ggtatcgctt ctttaagaga tctggcagaa gaaacaatcg ttattgactg
     4021 gcgcgcacca attgccaatc tttattatga aggtgagatt ggtcccgcat tttatgaaac
     4081 tgaaacagat agaatagatg tcgatctgca gttgaaacga caatttaaaa tccaagaagg
     4141 acgtatttta tctatggtag atacgtcgga agtaatcaat gatgactttt tgctagagat
     4201 attggatgaa tcatcaagca accatatgaa aaacatcgtc tctacgatac aaaaagcaca
     4261 aaatgcaatc attcgggaca caacaagtaa agtaatgctg attgaaggaa tcgccggaag
     4321 tggaaagaca tccgctttgc ttcaacgtat tgcttttctg ttgtatcata atcgcaagtg
     4381 gctcgaggct gaaaacgttc ttctattttc acccaaccat ttgttttctg attacatctc
     4441 gactgtattg ccttcattag gtgaaagcgg cgtgcctaca cagacattca aaaattattt
     4501 ggtgcagctg ctgccagagt tttctttact agatgaacag caacaagaaa gtggtttttt
     4561 gctaggggaa aaagatccga tacaagtgat gaaaagcgga ttgaccttag tcgatcagat
     4621 tgatcgctat atccaaggca tcacaaacta cggtcccttg ttccgtgata tgaaaataaa
     4681 tggccgtacg atcctatcaa aggaatcgat tcgccaatgg tataaagaaa caaatgaaca
     4741 attaccttta catcatagac tttctctatt acaaacgaag ctcctgaaaa aattaggcgg
     4801 tctgcaaaaa gacgaaacac gtcagcaatg ggtcaaagat ctggcggaag aacagctcca
     4861 agaactatac gcaacagatc caaatcttga atatacagaa caaaaggagc gttcattacg
     4921 taaaaaactg gccaaccaaa tcgtacgtaa aagattccgt cgaatccatc gagggatcat
     4981 gaattatcaa tttgtcaata taacgaaaca atatctccac tttctacaaa ctgtgccact
     5041 ttctcttcta acacgacata aaatcagcga gaccaggtgg caggaacatt tgacaactgt
     5101 tcgtacacac ttgcgtcaaa gagaattgcg tcaagaggat gctgtactat tctttttact
     5161 gatgcgccga acatatccag tgacggttac acacaaagct cgctatatct ttattgatga
     5221 aatgcaggat ttcgcaccat cacaagtggc attgctgcaa gccttgttcc caaaagcaaa
     5281 tttgactttc tgtggagatc taaatcaaaa tgtctttgga aatgaaacga tcgttggatc
     5341 attggaagac cttttcgtgg accgtgaagt cactcgtttc caattaacga caagctatcg
     5401 ctccacaaaa gaaatcactg attttgctaa tcattttatt gtgaaagaac atcaagtaga
     5461 aacaacagca agaaaaggag accttccttt gctcatccaa ggaacaacag atgatatcaa
     5521 attgaattgg ttagcagata ccattcgaac gactcaggga aaagcccggt attggcgtac
     5581 agcaatcata gctaaaacac aagaagaatg cgaagctctt tatgctcaac tgccagacga
     5641 gttgaaacaa caagtccagc tgattttaaa tgagagtgac tttatgaagc gttccattat
     5701 tttacttcca gcctttttag caaaaggtct ggagtttgac cgagttttct tgtgggatgt
     5761 agatgcagaa catttttctt ctcagcaaga caaattgatc ctttacacca tgtgtacacg
     5821 tgcgatgcat gaattgaccc tttttacctc caataatgaa agtcctttgt taaacaatat
     5881 ggatatttca tcttatgaga aaaaagtact gtaagtaaaa agacaactgc tatcattaat
     5941 gttagcagtt gtctttttat ttacaataat aattgcagaa aaagtaattc aatcatttaa
     6001 ggtcatttat tctatatata aatccaaatc tgtttcagga tattttaatt tgacaagcga
     6061 aataatcatt ttcagttctt ccatgttttc tggatattct gggtcaaata ccttgctatg
     6121 acggccaatc ccgccattgt cgatcaatcg gtaaattcga ttccattcaa tgaattggtc
     6181 aattgattgg aaattgctga ttggatagcc gccacaatcc aaaatctctg atacacgaaa
     6241 tgctaggtat gcactatcga tcactttatt ttttttcgtg tctatcttct catttctttc
     6301 gataagaatt ttttcaggac gatgtttcaa gctccactct aatagtagaa agaaagcctc
     6361 catccgatac tcttcttcaa ataaccgaaa ggctgaatca gaacgacgaa aaagcagcgg
     6421 aatcagataa ttttgtctat aaatcagcat tggtgcgcgg tccaccatac actctaaata
     6481 acggttcaga taccctgtac cgacatagtt tcctaatcga tagccttcaa cgccgaatct
     6541 tgcgtatttt tgcgctaatt ttgaacaatc agttacgttc acagctaact cttctacttt
     6601 gcggtaaccg cttaagatac gttcaaaagg ttctaaagtg atttttgctt ccatattctt
     6661 ccccgtccat cttccacata cttcatatca tttcacatga tacttatgct ctcatcatac
     6721 cacaggttga attagaaaag aaaataaatc acacaaaaaa gcaagacaat ctgttagtga
     6781 gattgtcttg cttttcgaaa aagactgaat acttttcgtt aaaactggtt gcttagtctt
     6841 ctaatgccac attatggaac acatgctgta catcttctag atcttccagt gcatcaatca
     6901 ttttttcaaa tgtttcttga tcttctggag atagtgttac ctcgttttga gggatcattt
     6961 ggatctcagc gattgaaaaa tcagtgattc ctttttcttt taatgcttct tgtatactat
     7021 ggaaatccgc tacttcaccg taaacgatga tttgtccttc ttcttccatt acatcgcgaa
     7081 catcgatgtc tttttccatt aggtattcaa ggatctcgtc agcgtcttct cctgcaaaag
     7141 caaagattgc tgtattgtca aacatgtaag aaaccgctcc ggaaacaccc atgttcccgc
     7201 catttttccc aaatgctgcc cgtacgtctg ctgctgttcg attcacattg ttcgtcaatg
     7261 tatcaacaat caccattgag ccgcttggtc caaatccttc atagcgcaat tcagagtatg
     7321 tttcatctcc tgcacctttt gctttttcga ttgctcggtc aataatatgt tttggtacat
     7381 tataagtttt agcgcgatca atgacgaaac gtagtttttg gtttgcatgc ggatcaggat
     7441 cacctgattt tgctgccgcg tagatttcaa tcccaaattt tgcataaatc cggctattat
     7501 tagcatcttt agcagttttc tttgctacga tatttgccca tttacgtccc atattttcac
     7561 ttcgctttct gatttgatag tttcataacg caaaaacgtc ctgttccatt atacttgtga
     7621 atcacgattc tgtgaagctt tttttctttc ttccttcatt cttctcattt ttagtcaatt
     7681 atctatactc ggattgggat ttgcccgaaa ttctgttccg gaatattgcc tcccaattga
     7741 tagatttgat cacttctaac taacagttcc gcttcttgtg cctctttttt tccgattcgg
     7801 gaataaatag aaatctcttt tttttctttt aagaatcttc ttccagcatc ggtaaatcca
     7861 agtagtcgaa gataattttt attttgttgg acaggaatct cttgcttttt gatattcagc
     7921 aagacataac aagataatcg ttggatccgt gtccatgtat atctttttgt ttttaccttt
     7981 gacacaaaat cctcaaaact atcagcagtt gcagctgctg ttttcatgcg cgattctatt
     8041 ccttcggtca tctgatagat atctgtcagt tccagcaaag tagaagataa caaccgataa
     8101 cgcaaatacg gccaataaga ttcccaagtc tgcagcgaac aagttgaaag atcttcttct
     8161 gtctgaggcg gcacaagtcc agctattctt tttccttctt ctaacgcatg gcgaatggct
     8221 gttgcactgg ctatcctctg atctgtgatg attttttcat gatagcctgc acttttacgt
     8281 cggatcggat gtaattccat agggtggaca tacttggcat tttcctttgc ataacttaat
     8341 cccaagatat gatttggcga agaaaaatca agcgtaatat cgggatacag actgcgaaaa
     8401 acctcagtca ttttttgcgg ataactatac gtttgatcag acagttcttg aaatgcctct
     8461 tctatcctat cttgattctc ttggacaaag cgtccgaaac tgctgtaatc aaacgaagtc
     8521 tcttcttctg ttccaaaaca caaactgtca cagtccagtg tttgcaagat ttttactgca
     8581 cctttagcaa aatagtcagc tgactgaacc gcccattcga cgggaagctc cactactaaa
     8641 tccacaccat tttgtaaagc ttcattcgcg cgatgccatt tatcgatgat agccggttcg
     8701 cctctttgca aaaaattccc gctcattaca gcaatgacga cctctgctcc tgttattttt
     8761 cgtgccattt ccacatgata gcgatgtcca ttgtgaaaag gattgtactc tacgataatc
     8821 ccgcagcttt tcatgcgcat cctccttcat agttatcgat aaaaaagaaa tagagacaag
     8881 taaaaaaagg caaaaatcgg aaaaaatacc cgaactatat aaactattct cgcaaacaca
     8941 atacttctgc gacgaaaagc tgcactgcaa gagcaatgcc tatatcgttc ggatatataa
     9001 tttatgttga agatttattc ttttcttgtt aactcgagca ggcaaaaccg ctagtctttg
     9061 tatgctacaa agaaccagcg ctttgatttc tctgatgctg cttcgtctgt aaaatcagaa
     9121 aatgcttcga ctttcgaaaa gccgctgttt tccagcattc ttaaataact ttccaatgga
     9181 taggtacgct cttgatgtag ttcatcttca cgaataaatc gaccagaccc ttcttgttct
     9241 tcaacgaaaa aggtaagaaa atgttcgatg ctgtgtttct cgcttcctgg ataactatcc
     9301 cacaaaaaag caaaattatc cccttgataa tgatagctat attctggaaa aacctcatct
     9361 acttgatagg tggagtgtac gtcaaataaa aatcggccat tttcttctaa cgcttgatag
     9421 acttcatcaa acacttgctg tacctcttgt ctatttttca tatagcacag cgaatcagaa
     9481 aaacaggtaa ttgcctgata ttgtccgatt tctgataaat cgagcatatt gccttccaca
     9541 aattggatcg atgcgtcttc ttcatatgct cgctggctgg caatcatcaa catctcttct
     9601 gaaaggtcta accctgtcac tttatatcca tcttttgcaa aggcaaccgc taatgctcca
     9661 gtaccgcatg ccagttccaa aatatttttt gtgtcttctt gtaaatgacg tttcgaaaaa
     9721 gctaaccatt gctgataaag tgtttcgtcc atcacttcat cgtaaatgaa agcaaatgtt
     9781 tcataagcca tatgttaatc caaccattca ctaagatcga ctagcggagc atctgaccat
     9841 agtttttcca gattatagaa atttcgttct ggcgcatgga aaacatgtac gatcacatct
     9901 ccaagatcga tcaataccca ttttccgcct tcttttcctt caatacgttt tacttcatat
     9961 ttgttttctt cttctttatc aatgatttct tctgtaattg cgttgatttg acgttcgcta
    10021 tttgctgaac agatcatgaa ataatctgcc aacaaggaaa catttcgaac gtctaaagcg
    10081 ataatgtctt ctgcccgttt tgaatctgct gcttcaatcg caatttttaa ttgttcttta
    10141 ctatctatga tgatttcctc ctaatatgag cagcttattt ttttgctacc cagtaattat
    10201 atgtttcgat tgtttttgga taaatctgtt gttcttgcgc aagcaaatgg gccaatgtat
    10261 gttttgtttc aaatgctaca gcttcgtcta gatcagccca tgcaatggct cgtgcatctt
    10321 gtaccccagg aaaatctcga cctggttcaa tatagtctgc tacataaatg attttgtcaa
    10381 ggagactcat cttagcagcc ccagtcgtat gcacccggat tgcatgaaga atctctgcat
    10441 cggtgattcc taattcccgc tctacaaacg aagcgccaac aagaccatgc cagattgcat
    10501 tattataatt caataactcc ggatcaaaac cgtctcttac gattaccatt ttgaactcct
    10561 catctggtcg ttcttttgca taatcatgtg tcaatgcagc aatactagct ttttcaggag
    10621 aagcaccgta ttttttggca agagccacgg ctgtttcttc tactccaagc acatgcttga
    10681 agcgttgttc gctcattctc atctgtattt tttgcatcag gttttctcta gaataagcag
    10741 tatattcatt actatagtcc atattcatac aacccttcat tttgaatata atcaattact
    10801 ttatctggaa caaggtagcg gatagaacag ccttctttga tcttttgacg tattttcgtg
    10861 gaactgatgt cgatctcagg tacatctacc caaattacag gatatggagt atccgttgtg
    10921 tatcctggtc gacgtatacc cacaaagttg accatagaag tcagctcatc gattttatac
    10981 cattttggca aatattctac catatcccca ccgataataa agtaataatc tgtatccgga
    11041 ttgttttgcg tcaattcctt catagtatca taggtgtaac ttttcccacc acgagctaat
    11101 tcaatcgttt caatctgcaa aaaaggattg tcttccaccg ctaattccaa catgttgagt
    11161 cgatgttttg catcaatcgt ctgtttctca tcaacatgag gtggctgata agaaggcatc
    11221 aaaaatacgc ggtcaagacc taaattccgg ccagcttgtt cagccatcac taaatgtgca
    11281 aggtgaacgg gattgaatgt tccgcccaag atccctactt gctttttctt ctctaagaat
    11341 tgaggcattt cttcaggaaa taattgtgaa cgaacaaatg tcttagcttg cgtattcatc
    11401 atggtcactc cttatattgc ttttacttct tttgatagcc tttgatactt ttcttttgtg
    11461 gaaggtttgt ataatacaat aacacgtcca atgatttgga cgatttcgca atctatttct
    11521 ttttctaata cttgagctgc ttcttctgca atctcatctg tattttgaag taacgatact
    11581 ttgatcagtt ctcttttttc taaagcttct tcaatttgaa cgatcattgc tgaattgatc
    11641 ccaccttttc cgatttgaaa aatcggctga agatgatgcg ctttgctacg taaaaaacgc
    11701 ttttgttttc ctcttaaact cataattttc cttcttcctt aaatcaatgc tttgcgtttc
    11761 aatacatcta caccctttgg cgcccagccc gcaattacta ctggcgctgt tacagtgatc
    11821 cagcctagac cggcaaaaac gatgtctgtt ttttctttca cagaaaactc aaaacgaaca
    11881 agctccggaa atgcctcgac ttcatcagga cgaggaggct gtaataatcc acctacatgt
    11941 ttttgataaa attcgtctgc tttttccagt ttcgttcgat gaatatttac atcatttgac
    12001 acataagcaa taaatgaagc acgattgccg ctgataaaat caaatcttgc aagtccgccc
    12061 aagaaaagtg tttgcccttc attcagctga taaactttag gtttgatttc ttttaacggt
    12121 gcaatgatcc gcaaatcttt tttacctaag tagtgcgcca tttgatggcg atggataatt
    12181 cccggtgtat caatcaaaaa atgcccgtca tctaaaggaa tctcgatttt atccaaggtc
    12241 gttcctggaa actgcgaagt tgtgattaca tcttgtactc ccgctgtatt tttgatgatt
    12301 tgattgataa gcgtcgattt tccgacattt gttactccga cgatatagac atcccgtcca
    12361 tcgcggtatt cttcgatttt ttctaatagt tccgtcatct catgagattt cttagcacta
    12421 gttaataata catctactgg acgaattcct gcttcgtaag cacgttcctt catccattgt
    12481 gttaatttag tttttttcaa tgatttaggt aatatatcca ctttgttccc aactaaaagt
    12541 actggattgt caccgacaaa acggtgtagt cctgggatta gtgaaccatt gaagtcaaaa
    12601 atatccacca cattgacgat caatgcatct ttttgcccta attcattcag taagcgcaaa
    12661 aagtcgtcat ccgtcaatga gacatcttgg gtctcattat aatggcgtaa tctgaaacaa
    12721 cgctgacaat agacttcccc ggaagctaaa cctttttcca aagccgtttg cggcgtgtat
    12781 cctaattcac cgggtttgtt tgtttgtata acggcaccac agccgataca ttgtaattct
    12841 tctgtcattc gattccacct cgccagccca tatcagggtg ttttgctaat agataggcca
    12901 taattctttt ttcccaaaaa cgattaaatt gtgtcttcca actatctgtt gcgataatgg
    12961 gttttacaag gatgctacgt atccctgcac gattggctcc acgtatatca gtcataatct
    13021 gatcgcctac cattactatc tcatcatctg ctaaatccaa ttgtttcttt gctatgttga
    13081 tccctcttgc taaaggtttc attgctcgtg caacatacaa aagatcaaat ttttcaatcg
    13141 ctcgcgcgac acgttttgaa ttattgtttg aaacaacaac aacagggatt cctgcatttt
    13201 tcatttctaa aatccaagta agcaactctt ctgttccatc tggattattc catgcaatca
    13261 acgtattgtc taaatcggtc aatactgctt tgatgcctag attctttaat tgggcaggtg
    13321 taatctgata gatggcttct accatccatg ttggtttgta atttgaaaac atgctgtctc
    13381 ctcatctgca aaaaatgaag gagcacataa agtactcctc aaccccgtat tatactgcat
    13441 atcagcaaaa aaaactacct ctatactcgt tcgtctttca gaaaaagcat ttctttacaa
    13501 aatgaccaaa aataaagatt gatcacagaa aaatttagaa acaaaaaaca actaatattg
    13561 gcggaacctc ttgtatcgtt tttccagtaa tttatgctga tctaatcgaa caagttccgt
    13621 caatctttca atcaacgctt ttttcataat gtgtgcgact ttatatcgtg gcaactgctc
    13681 gccgttgaac gtttcaggaa taactcgatc aacgattcct aactcgcgta gttctggcgc
    13741 agtaattttc atcaactcag ctgcttctgc ggcgcgacta ccgtctttcc acaaaatcga
    13801 cgcaaatcct tctggagaaa gcacagcata aatcgtttct tccagcatcc agacttcatc
    13861 cgctaaacct agagcaaggg caccgccact tccaccttca ccaatgatga tggcgatgat
    13921 cggtaccttt aaatcagaca tttcgagcag atttctggca atagcctctc cttcgccgcg
    13981 ctcttctgct cctacaccgc aatatgcacc tgctgtattg atcaaggtaa tcaccggtct
    14041 attgaacttt tccgcttgtt tcatcagtcg taaagctttt cgatagcctt caggatgggg
    14101 agaaccaaaa tttctgcgga tattttcctg cagatcccgt cctttttgaa taccgatcac
    14161 tgttaccggt ttgccatcta atcgagcgat tccaccaaca atcgcttcgt catctgcaaa
    14221 taaacgatca ccatggcatt cctcgaaaga atcgaagatc tcttcaaaaa aatccaagct
    14281 tgtccatcgt tctttagctc ttgctaactg aacgacatca tgtgctgtct tatccacgat
    14341 ctatccatcc tttctgtgta tgcaattcaa gaagcgtatg gattttctgt ttcaattcca
    14401 tgcggggaac aatctgatcg acaaaaccat gagataataa gaattcagcc ttttggaaat
    14461 cttctggaag ttcctgcttg atcgtctgtt cgatgacgcg tcttccagca aaaccgatca
    14521 agctttgggg ttctgctaga ataatatcgc cttccattgc aaaactggca gttactcctc
    14581 cggtcgtcgg gtccgttaaa acagttagat aaaaaagacc ttcattgcta tgccgtttga
    14641 cagcagcaga gatttttgcc atctgcatta gagaaaagat tccttcttgc atccgtgcgc
    14701 cacctgaagc tgtgaacaag acgactggaa gactttcctt tgttgctcgt tcgaataatc
    14761 tggtgatctt ttctccgaca atcgttccca tacttcccat gataaaatta ggatccatca
    14821 ctccaataat gaagggaatc ccctgaatgg ttgctttacc agtgaggact gcttcatgaa
    14881 gtcctgtttt atcttgcatt tttttaattt tttccgtata ttcgggaaat gctagcggat
    14941 ctttggttac aagatccgta tcccattctt caaaactttt ttcatcaata atcaaagcta
    15001 gacgctgcca tgcaccgatt cgaaaagcgt atccgcaatg agggcatact ttttcttcac
    15061 cgatgtcttt cgtataaagg atatgtttgc aatttggaca ctttgcccac atgttatcag
    15121 gaacagatgg cgagttagca ggtttgctct ctctattagg attgatccga atatatttct
    15181 ttttcttaaa cagagccatc tatgcgcctc ctatctccgt ttctggtgtc caattcggta
    15241 aaaattcttc ttgtaaaaat gctgtgctgt aatcacctgc tatgactgca ggatgactaa
    15301 tcaaatccat ctgaaattct gcgttcgtga tgattccttc tgtgataaat tcacttaagg
    15361 ctcgctgcat cttcattaat gcttcaaaac gcgtatttcc atggacgatt atttttgcaa
    15421 tcattgaatc ataatatggc gggatcgtat atcccgggta aactgcactg tctactcgca
    15481 gtcccatccc acctgctgga agcagtaagt tttggatctt ccctggagaa ggagcaaaat
    15541 ggaaagcagg attttctgca ttaatccggc attcgattgc gtgtccttgg aatactactt
    15601 cttcttgaca cacattcaaa ggctcaccgg ctgctatctc cacctgtttt tttactaaat
    15661 cgattcctgt gaccatttct gttactggat gttccacttg gattcgagta ttcatttcca
    15721 tgaaataaaa atcgccttct tcatccatca gaaactcgat cgttccggca ttttcataat
    15781 tgactgcttt agctgctcga acagcagcgt ctcctagtgc ttctcttttt gtttgtgaga
    15841 tcactacaga aggagattct tccagtactt tttgattgtt gcgttgtaaa gaacaatctc
    15901 gctcgcctaa atgaatgaca tgaccaaatc gatcacctaa gatctgaact tctatatggc
    15961 gagcaggata aatgattttt tccaaataca tatcatcatt tccaaatgcc gctgctgctt
    16021 cttgctgagc tgaagaaaaa tgctgtggga gctcttcttt tgattgaact ttccgaatgc
    16081 ctttcccgcc accacctgca gctgctttca gcatcactgg ataaccaatt ctgtctgcta
    16141 tttccaatgc ttcttctact gtagataata caccagtact tcctggaatg actgggacat
    16201 ttgcttcttg catcaattga cgcgcattga tcttatttcc cattgcatcg atcgttgcac
    16261 ttttaggacc aataaatgtg atattgcact cttcacacat ggaggcaaat cggctatttt
    16321 cagataaaaa accaaatcct ggatgaattg cttcggcttt tgtcacgatt gcagcgctca
    16381 gtacttcctg aacattcaga tatgaatcaa cggcttttgc cgggccaatg cagattgctt
    16441 catctgctaa ctgtgtatga agtgcttcgg catctgcttc tgaatatatc gctacggttt
    16501 ggatccctag ttcgcggcat gcacgaatga tacgtacagc gatttcaccg cggttagcta
    16561 tcaatacttt agaaaacata tttcacctat ccaatcataa aggttaattc cgcttcggct
    16621 acttttttac cgtctacttt agcgattcct ttgcctattc cggctgaagc tttcactttc
    16681 aatatctcaa cttcaaggta taaggtatct cccggtgtaa ctttcttacg gaattttgct
    16741 ttgtccaatc cgccgaaata agccgtcttt cccttgaatt gttcaagaga aagtaatgca
    16801 actgctcctg cttgagccat tgcttcaaca atcaataccc ctggcataac aggttcttct
    16861 ggaaaatgtc cttgaaaaaa gggctcattg atcgttacat ttttcttagc aacgatccgt
    16921 tctccttcaa ccatttcttc cactcgatca atcaaaagca ttggataacg atgtggaatg
    16981 atttctttta tttcttgtat gttcattgtt ttccctcttt cctgctttgc ttatttttgc
    17041 tgaatcctaa agagtggctg tccatattcg acaactgact cgttttctac aaggatttct
    17101 gtgatcactc cgtcggcctc actagttatc tcattcatca gtttcatcgc ttcaataatg
    17161 cagataactt ctcctttggc aacttgatca cctacttttt tgaaagctgg tttgtcgggc
    17221 gctggttgca gataaacgat tcccacgatt ggcgaaacaa cctcgattcc atcaaatact
    17281 gccgattctt tttctttcat tatttctgga gcagttgttg cttgttcagg tatgacattg
    17341 actggctccg aaactggcaa cgtttcgttt gtttgaacca tattcatgcc tcgacttgtt
    17401 ttatttttat tcatatacaa ttcaaattga ccttcacgca aatcgaattc cgttagcgag
    17461 gattgatcaa attgactgac taattctctg atttcattga tatccaaaat tattcctccc
    17521 agcgtttcat gcacagaacc gcattatgtc cgccaaaccc taatgaatta ctcattgcat
    17581 aagtaaaact tgcaggtttg ctttcgtttt tgacaactgt caagtcaatc tcaggatctt
    17641 gtttttctac attgatcgta ggtgggataa attgatgttc taatgccagc aaagttgcca
    17701 aggcttcgat cccgccggct gctcccaata aatgtccagt catcgatttc gtgctgctga
    17761 cgtaagtatc tctgaaattt tcacctaatg cgatttggat tgcttttgct tctgcctggt
    17821 cattggctgg tgtacttgtt ccgtgagcat tgatatatcc gacttgttcc ggctgtacac
    17881 cagcttcttc catcgcaagc ttcattgctt tagatgcacc agaaccatct ggagtaggag
    17941 ctgtcatatg gtaagcgtca cagtttgcac cgtatccaac gatttctcca tagattttgg
    18001 caccgcgagc ttgtgcatgt tctaaagatt caagaactag aacgcctgct ccttcaccca
    18061 tcacaaaacc attccgattt tcgtcaaacg gaatcgaacc acgattagga tcagttgatt
    18121 ctgagagtgc tgttaaagct gcaaatccag caatccccat ctcacaaatc gttgcttctg
    18181 ttcctccagc aagaatgaca tcagaatagc catgtttgat gttacggaat gcttccccaa
    18241 ttgaattcgt tccgctagca caagctgtta cgatagctgt acaaatacct tttgcaccta
    18301 cacgcaaagc aatatttcca gctgccatgt tggcaatcgc cattggtacg aacattggag
    18361 aaactcgttt tgcacctttt tcatgtagac gaataacttg gttttcgatt gttggaagac
    18421 caccgatccc agatccgatg atgacgccaa accggtcttg attcattttt tctttatcta
    18481 aaccgctcat ctccattgct tctaaagcag cgtagattcc atagatcgaa aacatatcca
    18541 ttcgtttgct atctttttta ataaaatatt tatcgtaagg gaaatctttg acttcacccg
    18601 ctaaggtaat ccctgtttct gaagcatcaa atttagtgat cggtgcgatg ccattcgtcc
    18661 cctcttttaa gctattcaaa aagctgtctg cgtcatttcc aataggtgaa gtgactccat
    18721 agccagtaat taccactcga ttcatttgtt tgctctcctt ttcttatccg tgcatgacca
    18781 atccgccatc gacattgatg acttgtccgg tgatatatgg attttgtgct aagaaaactg
    18841 ctgtttgtgc aatatcttct acttgtccga aacgctgcat cggaatttgc ttttccgctt
    18901 gttccttgac tttgtctgct aaaacttccg tcatatcagt tgtgatgaat cctggcgcaa
    18961 tggcattaca tgtaatgcct ctagttgcag cttctcgtgc cacagatttt gttaatccta
    19021 ctacgccagc tttactagct gcataatttg cttgaccaat atttccaatc aacccagata
    19081 cactagagag attaatgatg gccccttctc gctgcttcat catttttttc aatacgtgct
    19141 gcgtcatatt gaaggttcca atcaaattga tatccagaca ttttttgaaa tcttctgcat
    19201 ccattcgcat cacaagtttg tcatttgtga ttccggcatt gtttactaac acatggatcg
    19261 atccaagctt ttcttctgct tctttgatca tttgtcccgc tttctcataa tcagagatgt
    19321 caccggaaac tcctacgcat tttacaccga atgcttcgat ttcttctatc ttttcttttg
    19381 gaatctctcc gcgaccattc aaaatgatat ttgctccagc ttttgcaaaa gctaaggcca
    19441 tcgctttgcc gattcctctt gtactacctg tgataaatac attttttcct tttacatcca
    19501 taacgttcct ccttatagta ttgctattgt ttcatcaaat gtctgcttat tctcaacacg
    19561 cagaactggt attgttttat cgattttttt cataaatccg cttaatactt ttccggggcc
    19621 gacttcgatg acttgttcga tgccgattgt ttttaactta tggatactct catagaaacg
    19681 aacaggttgc atgacttgct gttcaagtag tcccgcgatt gtttctttct tcattatttc
    19741 cgttgttgtg ttgcttatga taggaaaaga aggttcagag aattgaatct gacttaggtc
    19801 cttcgccagt ttttttgctg ccggttctaa aatagctgta tgaaaaggcc cgctgacatt
    19861 tagagggatc attcttttga accctttttc ttttaatagt aaaacagctt cgtctactgc
    19921 tttttcttcg ccaccaatca cgatctgctg aggtgtatta taatttgcag gagatacgat
    19981 gccgtacttg ctagcttcat gacagctttc ctcgatcgtt tcaatcggcg cattcatcac
    20041 tgcaaccatt ttcccgcttc cagctggggc agcttctgtc atataagcgc ctctttttgc
    20101 tactaacgca actgcttcag tgaaggatag cgcattacta gctactaatg ccgaatattc
    20161 tcctaaactc agtcctaaag ctgcatctgg gatgattcca tgctccttca ataagcgata
    20221 atacgcgatg ctgactgtta gaatagctgg ctgtgtatat tgcgtctgat ccaaacgttc
    20281 attttctgta aagcaaagtt cagccatatc gtagccgaga atctcacttg cttcatcaaa
    20341 tgtctgcttt acaacggctt cttcatataa atcttttccc ataccttgat attgtgcacc
    20401 ttggccacta aataagaatg ctgttttcat gtttttctcc aatatatcca gaatatatgt
    20461 ttgattcttc ctattcaaaa aggccgagac attcctattt caggaaatgt cccagccccc
    20521 aacctaattt taatgattat gcagtttgtt tttctacgta agtcactaaa tcttgaaccg
    20581 ttttgattcc gtcttctgtt tcgattttca cgtcaaattc atcttcaatt tcattgatga
    20641 tttggaataa atccaagctg tcagcttcta agtcttcttg gatgtcagta gtcaatttga
    20701 tttcttcagt ttcttttcct aattcttctg cgatgatttc ttgaattttt tcgaatacca
    20761 taataatata ttcctccgat attgtttgct ttttattttt ataatttaac agtctacaac
    20821 tccatgagaa tacttcccca tgttaaacct ccgccatagc ctgtaaatat tactttctgc
    20881 tgttttccta aggtgatctt tccactagaa actgcttcat ccaataagat agggatgctt
    20941 gcagcagatg tattcccata tttatccata ttggtcagga acttttcttg cggcatcttt
    21001 acttttcggg caattttctc aataattctg aggtttgcct gatgcaaaag cagataatca
    21061 actggtttgt ctttcatgac ttcttggata ttgtttgcaa cgtctcgtac ggcaaaatca
    21121 aaaatatctc tgccagtcat ttgcaaataa tacgaacctt ctgaatcttc tgaatagaac
    21181 ggatttttat tttgctggta gccagcggtc aatgagctac ttctggtacc gtcagctgct
    21241 aatttttctt tcagcaattt tttctgtgga ttcgcttcta agagaatccc acctgctcca
    21301 tcgccaaaca acacagcagt cgtacgatca gaccaatcga ttagcttaga tagtgtttca
    21361 ccaccaatca ccagtccctt agttgagccg cagcggatca ttttttcagc catgcttaac
    21421 gcataaacaa atcctgagca cgcagcactg atatcaaaag cgatagcatg agttgctccc
    21481 aatttccctt gtacttgtgc tgctacagat ggtgtcgtgt aatcgggcga cattgttgct
    21541 actaaaataa aatccaaatc tttagggttt agatttttct gttttatcaa tttttccgcc
    21601 actaaaatgc ataaatcaga agtctcctga tttgttacac atcttcgttc acgaataccc
    21661 gtccttgacg aaatccattc atcagaggta tccatcatct tggaaagatc attattagta
    21721 ataatctttt caggaaggac gctggctgtt gcagtaatca ttccaaattg ttccattaaa
    21781 tatcctcact tatagtcttg caagaagtcg tgcaagtttt tcagtgcatc cagcaaggca
    21841 tgctgttcct ccgtagccat tccgtctaag atgttcttga ccatttcacg atgaaaatgc
    21901 tgatggaccc gaaatagtaa ctttcctttt ttcgttagtc ccaactttac aacgcggcgg
    21961 tcatcttcac tgcggatacg ttcgacatag ccttttttta ctaacttgtt aatagcagtg
    22021 gtcaaggtcc caacagtaat tgatagttct ttggctactt ctgaagttgt ttttttcttg
    22081 tacatcccga ttgcctcgat cgtgtgcatc tctgtgattg acagatcttt gaattgagat
    22141 tttttcagct cagactcttc gattgtcaaa atatcattga agacactaac aagataatca
    22201 tttactgttt ttaaatctgg ttccatgttc caccgtccac taattagttt gattatcaaa
    22261 tcttttgatg ttcaaactat atcttaactt ttttcaaaat gcaaccttaa aagatcattt
    22321 ttttactata tgagcttttt ttaagatttt actcatttaa aacaactgat aaatcagcat
    22381 ttataatttc ttttattaga aaaatcatct atctcacata ttttgattat caaagtattt
    22441 tctgtgaaca gaactataga attccctaaa acttgtccat tatttcaaaa tttgttatag
    22501 tctttttatt caaagcgtaa aaggagatcc tatgttaaaa gaaaaaatga aaactctccc
    22561 catgctgccg ggtgtctatc ttatgaaaga ccgagatggt aaggtcatct atgttggtaa
    22621 agcaaaacgg ctcaaaaata gagtaagcag ctattttcat cagaataaac agcattcaaa
    22681 aaaagtatta cgtatgattc atcatataac agattttgat ttcgtcgtag tagacacgga
    22741 attagatgct ttattgctcg agtgtcaatt gatccaacat taccgtcctt tttataaccg
    22801 acaaatgaat tatttcagta attataatta tgtacatatt accaataagg gatttgtatt
    22861 aacagatact cctacggctc gaacatacgg gccttttcgt ctctataaaa aaatgccgtc
    22921 tattttgcgt ataatggaag aaacttatca aatgccttgg ttgtctgaaa ttagtttgtt
    22981 agctttgcga gtccagcttc ctgacctaca ggaaatgact tttgaacaga aaaaaaagga
    23041 actccaaggg ctgtttcaag gccgaaataa aaagctactg acttacttga aaaaaagaca
    23101 acaacatttc atctatcagt tgaatttcga aaaagccggt atgcttcaaa aagatatcga
    23161 attagttact tattttatta gacggatcca ggaacaaaag cagtttttaa gaacaccatc
    23221 gctcaccttc agcatgccat tagcagcaga tgagagtcag aaaaagcact acctcgtttg
    23281 ttatggtcaa cttgcagaaa caatgattac ctctggtgac gtttctcctg acttctatta
    23341 tgaaaagaaa gaagctcatt tatctttgaa acgtcaattg tcaaaagaag aaatcgatcc
    23401 tgtacaaatc ttgatcagtt accgcaaaaa attagaaaaa gaacagtttg aaattgaact
    23461 gttaaacaaa aaagaagctg aaaagcaact aaattagttg cttctcggct tcttttaggc
    23521 atcttcaact tcaaatgtca attatcctaa aatttattgg attaagtcat agatttccat
    23581 cgctacgata tcgatattat caaattcgta ttgctgatga gtatctgttt cagttaattc
    23641 aaatgtatcg gtcgctttat cataagttac tgtacacttc tctacgcctt ctttttcaaa
    23701 acggcgaact tgcagttcat tatctgctga ctcgaccata gcctccagtc gttttatgat
    23761 tgcgactaat tgtgaatgtg tcatcggagg tcctcctttt cttatttctg ttatattgta
    23821 tcaaaagcat agcctacttg cattgatttt ctctaaaaaa actcgttttt tatgattttt
    23881 tttctggtat ttttccttca ggccaccaaa gtttgatcaa agcttgggtt ccgtcattct
    23941 caaaaccttt atctgccaac tcttcatata gtttcaatgc ttgggtagtt gctggcaata
    24001 caagatccat tttttctgct tcttctaatg caatctttaa atctttgata aaatgtttga
    24061 caaaaaaacc aggtgtgtaa tcttctttta aaatacgagg agaataattg cttaaagacc
    24121 agttagctgc acttccacct gaaagcgtct caatcacttt ctttaaatca agtccgtttt
    24181 tttgtgcata gacaagcatt tccgtcattc ctgtcatcgt acctgcaatc atgatctgat
    24241 tagccatttt tgtatgctga cctttcccag cagaaccatg caatgtaaat gtcgtaccaa
    24301 attctttgaa taaaggcagt acttgatcat aaacggcttc ttctccaccg accatgatcg
    24361 tcagtgtacc attctttgct cctaagtcac caccggatac cggtgcatct aacgcatctg
    24421 cgcctttttc ttttgctgtt tttgcaattt tttctgccag gcttggtgta cttgtagtca
    24481 aatcaactaa aatatgtcct gagatatctg cagaaaaaat ccccgactgt ccatagtaga
    24541 tttcttctac atctttgggg taacctacca ttgtaaagag aatattactt tgttctgcta
    24601 ccgcttttgg tgtatctgcc cagatagctc cttctgttac taaaggatca gcttttgctt
    24661 ttgtccgatt atagacagct acttcgtgtc ctgcttctag tagatggcgt gcgacagcac
    24721 ttcccatgac gcctgttccg ataaaaccaa gtttcatttt ttcgacctcc taaaaatcaa
    24781 aaatccttgc ttctatgcta gtatacgcta gaaacaagga ttttttcata aaaaatgttt
    24841 gaattttatc ttttaaatga atttaatttt attttgattc gttcaatcga gtcttcttct
    24901 tcttttcttc gcatctcttc ttcatgataa acaaccatgt cttgataaaa ttcgatcata
    24961 gcttcgccga aatgtgtaga tgaaatatca taaagtttag cttctaaaac ttttggatct
    25021 ttaggaactt cactggaaat ataatcaata agtgctggtg caaagtcttc gtcggtttca
    25081 aaagttttcc ctaatgaagg atgatcgaac aatcggttca aataagcatt tccttccacg
    25141 acacaaggtg ttccggctgc catcgcttct gtataagtaa gcccttgtgt ttctgaagta
    25201 gaagcactga caaaataatc tgccgcttta taataaagtg ctacatcatt gttgtccact
    25261 tctcctgtga actgcacaaa ttcttctaac tgcagttctg agatcaattc ctctaactct
    25321 tctacataag gtccttttcc tacgataact aatctggcgt taggataagc ggagatgacc
    25381 tgaggaaacc cattaatcaa ggcttggata tttttctcat aagaaatcct gcttaaagaa
    25441 agaatcatca aatggttttc ctgaagacct agtgactccc ttaatttgct gatatcctgc
    25501 tgagtgatat cagaacgttt gaatttttca atgtcgatac cagtaggaat cacgcgaagc
    25561 ggtgctatta caccatagct gcgtaatgta tcaataacac gttcacttgg acaaactaca
    25621 cctgtcgtat gatttgcaaa taatctagac aagtatttta catgggattg cctgatcact
    25681 tttcctttac cgatataatg aaggtagtct tcatacatcg tatggtaagt atggatcaga
    25741 ggtattttca acttcttagc taccatcttc ccaagtatcc ctgctccgaa ttctgtatgg
    25801 gtatgaataa gatctagttc tagttctttg gcaaccaaat aagcatacca catgcctcta
    25861 acaacaactc ttcgatcctt gaaagaaata aatggtacac ttggcattcg aatcacatct
    25921 ttttccaact tatccgcatt aggatcggtc gttgtaaaaa tatagacttc atgcccatgt
    25981 ctttctaatt cttgttttaa tgttttgatc gatgtagcaa ctccgctgac ttgcggaaag
    26041 taggtatcgg taaaaaagcc gattttcatg tttttcgcct ccaaactagt ccttgacctg
    26101 atttactttt tttaatttgc tagagacttt ttcattcagt acactttcgt atacattttt
    26161 aagttcttca ccgattttat tgatacttcg ctcttttgct gtttgataac cggcttgtgt
    26221 cgtactcggt agttcttgat tggtaatctg ttggatcagt cggataaatt cttcgtttgt
    26281 cttccccata tagcagttct tgctatcttc taaccagcca ttatacactg gaatatctcg
    26341 aacaagtacg ttttgtttgc ttgctaaagc ttctaaaaca acgatccctt ctgtctcttc
    26401 ataagaaggg aaaaagaata gatctgcacc tgaatacgca ccttctatga tctctccacg
    26461 aatgtaacca ggaaacagga cattttcagg atgatcttct tttacaattt tccggatgtt
    26521 ccgaggaatc gagtacatgg gaacatgacc aaaccaaata aatgtgtatt cgggcatctt
    26581 cttagcaatt tctacgaaat caatgattcc tttacgttcg aaaaacaaac cgacacaaat
    26641 gattactttt tgatccggag acagtttgaa atattctctg aacttttgtt ctttcattgg
    26701 atcagggtga tatttctcta agtcgatccc attggaaata gcttgaatcg gcacacggat
    26761 accatagctt tccaacaact gttttgaata aggtgttggc gtgatcagat agtccgcttt
    26821 ttggtacaat cctaccagat atttttttac gataggagaa agctggttcg atctgataaa
    26881 ggaatttcgg aaatcttcct ctgtagaatg cgcatgatag acaacttttt ttccttctct
    26941 tctggcttta ttgaccatat tatgactatt gattccgtat gtattgatgt gcaggatgtc
    27001 ataatcttct ttttcatcta gtgtataaga gataccgact tccgtcagag cacgtttttg
    27061 atgatcaagc gcacgcccga ttccagattt tgcaagcatc ttttcacttt caaaatataa
    27121 taataccttc accttacgtc ccccttcact tatatagtat aacatagcct acaaactgtc
    27181 actcaaactt aagccctatt tttgtctatt cttactgaca aaaacgtttt cttaaaaaag
    27241 aacaaaaaaa ctggcgtagc tcttttacaa gccacaccag cttttgatac gttgtttatt
    27301 ttacatattc atgaacaagt tcaacgactt cttccatcat atcgcattct ttcaatgcac
    27361 gatcagcaag ttcagccatt ttcgctgtgt ccaagcgttt cattaaacta cgcgttttaa
    27421 gaatagatgt cgcactcatt gagaactcat ctagacccat acctactagc aatggaacag
    27481 ctgtttgatc tccagccatt tctccacaca tacctgccca ttttccttca gcgtgtgctg
    27541 catcaattac atttttgatc aaacgtaaaa ttgatgggtt atatggttgg tacaagtaag
    27601 aaacgcgttc gttcatacgg tctgctgcca ttgtgtattg aatcaaatcg ttcgtaccta
    27661 cagagaagaa atctacttct tttgcaaact tgtctgctaa gactgctgct gctggaatct
    27721 cgatcatgat gccgacttgg atcgtatcag atacttcctt gccttcactt atcaattttt
    27781 gtttttcttc ttcaaagatc gcttttgctg cgcggaattc tttgagtgta gctaccatag
    27841 ggaacatgat acgtaaatta ccatgaacag atgcacgaag caatgcacgc atttgtgtac
    27901 ggaacatttc gtcgccttgt tcagataaac tgatacgcaa tgcacgatat cctaagaatg
    27961 gattcatttc atgaggtaat tgcagatatg gtagttcttt atctccaccg atgtccattg
    28021 tacgaacaac tacaggtttt ccttccatac cttctaatac agctttgtaa gcttcatatt
    28081 ggtcatcttc tgttgggaag tctggagaat ccatatacag gaattcagta cggtacagac
    28141 caactgcttc tccaccatta ttatggacac caactagatc ttttggtgtt ccgatgtttg
    28201 cagctaattc aaaatgcttg ccgtcagctg tgacagtttc tgcatttttt aatttttccc
    28261 attctgcttt ttgtgctgcg taatctgcac ctgctttttc aaattcagct ttttgttcat
    28321 ctgtaggatc gatgattaca tcgccttcga tcccgttgac agccaaaata tcgccttctt
    28381 tgactttagc agtaatttct tttgtcccaa cgattgctgg aatttctaaa gaacgtgcca
    28441 tgatagcaga atgtgaagta cgtccaccaa tgtctgttac aaacgctttt acaaaattgc
    28501 gatctaattg tgctgtatca cttggagtca agtcatgtgc aacaacgacc acttcttcgt
    28561 tgatcattga tggatttggt aaagtaacgc ctaataagtg cgctaaaata cgtttagcaa
    28621 cgtcacgaat atctgcagca cgctcttgca tataagcatt atcttccatt gcttcgaaca
    28681 taccgatata catatccgtt acttctttta gcgctgattc agcatttacg ctgttgtctt
    28741 taatattttg cttgatttga cctaccattt ctggatctga aagaaccatc aaatgggcat
    28801 caaatacttg cgcttctgct tcacctaagc tttgcgctgc tttttcacga atttgctgca
    28861 attcttcagt agatttagct aatgcagcat ccaaacgagc ttcttcagcc gcagtatctt
    28921 ctactgttgc cttactgaat gttaaatccg gttgaactag caggtaagct tttgcaacgg
    28981 ctacaccgtc actagcggca atccctttta gcatttcaac cattattcag ataagccttc
    29041 tttcttcatt gtttcaacga ttgctgccat tgcatcagct tcgtcagcac cttctgcagt
    29101 aatagtaaca tcagaacctt gacctacacc taaagacata acgcccatga ttgatttcaa
    29161 gtttactgat ttacctttat actctaagtt tacatcagag ttaaatttgc ttgctgtttg
    29221 tactaatagt gtagctggac gagcgtggat cccagtttct gctactacgt gaaattcttt
    29281 cttttccata ttaatcggtc tcctttaagt gagtgttgtt tttatgtgag ggttttcttt
    29341 tttagtaatt cagagaatcc taacaaatgc caccctttca tctgtaaaga ttaacatttt
    29401 ttttcgttag atacaacagt tttcattcaa tttcagataa aagtattcaa attattccgg
    29461 attctttttc atccttttct tcacatttta taacaaacgt gtttatttcc tttttcttgt
    29521 cgctttctct tctcctgacg tttatcattc tttcctttga ccctctttgt tttcatatga
    29581 aacgaattac ttgcttccct ttttattttt agtataataa gagtcaaagg tcaggaatgg
    29641 tcaatagaga tttcaccttt tctacctcat aaatctctta aaaaactagg ggttattctt
    29701 ttacctcatg aaaaacgaga tgtaaaatat ggatgtaccc atttttgtga aaggacgtga
    29761 atgattcatg ctttgtcaaa actgcggcaa gaatgaggca acgattcact tgtatgccac
    29821 tgtcaatggt cagcggacac aactcgatta ctgtcagagc tgttatcaaa aaatcaaaaa
    29881 tcaacaaaat ggaggtctga ctaatatggc ccaaaatgat ccatttggat ttggcagttt
    29941 ggacgatctt ttccgttcca tgtctcgcca aatgcaacag caaggaaatt atgagcaaac
    30001 accaccaaca caatttggcg gaaacaacaa cttcaatggt ggtcagccac ctcaaggcaa
    30061 tacagaaggt ttattgggag aatacggaat caatatcaca gaacaagcac gacaaggtga
    30121 tatcgatcct gtgatcggac gcgatgacga aatcaaacga gtcattgaaa ttttaaatcg
    30181 ccgaaccaag aacaatcctg tcttgattgg agaaccaggt gttggtaaaa cagcagttgt
    30241 tgaaggttta gcacaaaaaa tcgtagatgg tgatgtaccg caaaaattaa tggacaaaga
    30301 agtcattcgt ttagatgtcg tatctttagt ccaaggtact ggtatacgag gacaatttga
    30361 agaacgtatg caaaaattga ttgaagagat ccgtcaagca gaaaatgtga tcctattcat
    30421 agatgaagtt cacgaaatcg tcggtgctgg ttctgctggt gatggaaata tggatgctgg
    30481 taatatttta aaaccagctt tagctcgagg agaattgcaa atggttggtg ctactacctt
    30541 aaatgagtac cgcatcatcg aaaaagacgc tgctttagaa cgtcgtatgc aacctgtacg
    30601 ggtagatgaa ccaactgtcg aagaaacgat cagtattttg aaaggtttgc aaaaacgtta
    30661 tgaagactat catcatgtaa aatatactga tgaggccatc gaagcagccg caactttatc
    30721 caatcgttac gtccaagatc gcttcttgcc ggataaagcc atcgatttgc tagatgaaac
    30781 aggttctaag aaaaacttga cgatccaaat cgttgatcct aaaacaatcg agaaaaaact
    30841 gcaagaagca gaagaacaaa aagttttagc ttctcgagaa gaagatttcg aaaaagcagc
    30901 ttattatcgc gatcagatca ataaacttca aaaaatgaaa gaacgtcagc tcactgaaga
    30961 ggaaacacct gtgattaccg aaaaagatat ggaaaaaatc gttgaacaac ggacaggtat
    31021 tccagtgggt gaattaaaag aaaaagaaca gacacaactg aaaaacttag cagatgactt
    31081 gaaagctcat gtcatcggac aagataacgc tgtagatcga gtagcgaaag cgattcgccg
    31141 aaaccgtgtt ggattaaaca aacagaatcg tccaatcggc tccttcttat ttgttggacc
    31201 aactggtgta ggtaaaacag agcttgcgaa acaacttgcc tacgaactat tcggttcaca
    31261 agattcaatg attcgtttcg atatgtctga atatatggaa aaacatagtg tctctaaatt
    31321 gattggttct cctccaggtt atgtcggata cgaagaagct ggtcaattaa cagaaaaagt
    31381 acggagaaat ccttacagtc ttgtcttgtt agatgaagta gaaaaagctc atccagatgt
    31441 tttgcatatg ttcttgcaaa tcttagatga tggtcgattg acagatgcac aaggaagaac
    31501 ggtcagcttt aaagatacga tcatcattat gacaagtaat gccggaactg gtaaagtaga
    31561 agcaaacgtt ggttttggtg cggcacgcga aggtgttact cgttctgtat tgaaccaatt
    31621 aaacaactac tttacaccag aatttctgaa ccgttttgac gggatcatcg aattcagtgc
    31681 attatcaaaa gaaaacttga tgacaatcgt cacactaatg ctagacgatg tcaaccaaat
    31741 gctggcagca cagcaacttc acatcgaagt tcctacgaat gtcaaagaaa aattagttga
    31801 cttaggctat gatccatcta tgggtgctcg tcctcttcga cgcacgatcc aagaacaaat
    31861 cgaagatggt atcgctgaat tttatcttga tcacccttct atccatgagt tgaaagcaaa
    31921 actggataaa gatggaaaaa tcatcgttac ttctaaacca gaacgtttgg ctaaagaatc
    31981 agccgaagaa acggctgaat aaatccagtt ttatagcgtg agacggtatt tctttgagaa
    32041 atgccgtctc attctttttt cagaaaagtc aaaatactgt tcattttata aaaaagaaat
    32101 tataataaga gaaacaagca attaaaaata cataaaagag gtgagcgcca tgaaattggt
    32161 aaatgtaaca aacagccatt cccgtcttgt attaaaccag cttgaaaaca ctgatgccca
    32221 tctagtcaag gtctacacag ccggaaatac cactattgtc tacactgaag cccctgaaca
    32281 taatgaaatt ctgctgatca atgacaaacg taaaatccag ccgaaagaaa tcgaagatgc
    32341 taaaaattat ttcttagata aaatcaaaga cgccgtttac cacgaggatg aaatcaaagt
    32401 aatcgaattg gcaggccttg ttgaaatctc gattccaaaa catgaattag gcgctacatt
    32461 agccgtgtaa acaaattttg aacataataa ttaaagagcg tgggacaaaa gtaaagaaca
    32521 cttttgtctc acgctctaaa cacgtataaa cggcgaaagc agaagcaact ccttcggaaa
    32581 taagctgaaa ttcacgaaaa ttgcttttca aatttttgtg aattccagct tatttcttgg
    32641 agttaaacgc ttctgtctca gcctcttttt ctttctagct ttttgatttt tctcttttct
    32701 tttgtacttt tctcttttca ttttcagttc tacgcgtgtc tttattttta actttttcct
    32761 ctttatggat gattgatcgt actttttgtg caatttgctc gtttttgtcc cagtctttta
    32821 catctaataa tcgacataat cgtaacatct cttctttttt ctgttttttt ctttcacgtc
    32881 tttgccattc tgtttccatg tgtcacactc tcctttcttt aatcatatgt acgcaaaata
    32941 atttttatat ttttttgatt agacatttct atgattttaa tatagtaaaa agagccgtca
    33001 cggaaaatcc gtcacggctc taaacaaaat atgagaggct gtttttgttt ggctattctt
    33061 attacttgat gcagggcagc ttgtgtcaag acttctttac atcaaacttt ttaattttac
    33121 attgggatat ttatccgcaa accagcgttc tgcaaattgg ttctcgaata agaacaacgg
    33181 ttggtcgaaa cggtcacgag ccaagatatt gcgacttgaa ctcatcttct catccaaatc
    33241 ttctggatcg atccagcgag cgattttgtg tcccattgga gacatgatta cttcggcgtt
    33301 atactcattt aacatacgat attggaatac ttcgaattgt agctgaccaa cagctccaat
    33361 gatatattct tccgttagat atgttttata aagctgaatc gctccttctt gaactaattg
    33421 atagattcct ttgtggaagg atttttgttt catgacattt tttgcagtca ctttcataaa
    33481 cagctctgga gtaaatgaag ggagttcttc ataagcaact tttagttttc cttcgaacaa
    33541 tgtatcccca atctgataat tgcctgtatc atatacaccg atgatatcgc ctgctactgc
    33601 tttttcgacg ttttctctcg aatctgccat aaattgtgtg acattgctta atttcagttt
    33661 tttatttgta cgttccaacc agacatccat tcctcgttcg aatgttccag aacagattcg
    33721 gacaaaagcg attcggtcac gatgggctgg attcatattt gcttggatct tgaatacgaa
    33781 acctgaaaat tcttcctcat aaggacttac catctgatca tcttgtgttt tgtgtccata
    33841 aggagctggt gccaattcaa cgaaagtctc taaaaaagtc tgtacaccga agttagtcaa
    33901 tgcagaacca aaaaatactg gtgtctgatc gccacgagca attttttctt gattaaatgc
    33961 atctccagcc tctttgatta gttctacttc ttctaagact tgttcatata aggaattttc
    34021 agttagagga tgattttcgg gaagcagtcc atcttcatcc aattctacta atcgttcatc
    34081 ctgataattt tccggacgat aaaactctac acgattatgg tagatatcat aaagaccttc
    34141 tagcccttta cccataccga ttggccaatt catcggataa gattcgatat ctaatagctc
    34201 ttctaattct tctaacaatt ccaatggttc acgaccatca cgatctagtt tgttgataaa
    34261 agtaaatatc gggatgccac gtttttttac aacttggaat aatttctttg tctgtgcttc
    34321 gatccctttt gcactatcga ttaccatgac cgcactatcc acggccatca aagtacgata
    34381 agtatcttca gaaaaatctt catgtcctgg tgtatccaag atatttactc gtttcccttg
    34441 ataatcaaac tgcataacag aactagtaac agaaatccca cgttgtttct cgatttccat
    34501 ccagtctgat ttggcaaaat tacctgtttt tttgcctttt acggtcccgg cttgacggat
    34561 agccccacca aacaatagta attgttctgt aatcgttgtt ttcccagcat ccggatggga
    34621 aatgatcgca aaagttctgc gattgtccac ttgttgcttt aattttggat tattcataac
    34681 ctaactccat ttcttccatt caattattta tattttctct aggcacagat tgtccgatct
    34741 cttaaagaaa gacaatttca tatagggctg tgacaaaagc cgtgtagcag tctctttttc
    34801 cgagtaaacg gcgttctaga gacagcctat cagcaataag cccacccaag ccaaaaatac
    34861 gaaaagctgt ttttgcttgg ctgctcttat tacttaatgc aggatagctt tttcacaacc
    34921 tttgtcaact actacaactg aatcagtata gcatggattc agcgaatgaa aaagccacca
    34981 aaccataaga gtcaaatatt tttttgtcag ctgactaaaa gaaaagacgt gttgcttgtt
    35041 tattcaagca acacgtcttt cataaccaag tttccaatta tcttcttggc tcgtcatctt
    35101 cgaattcttt tctgaagtat cttcgttctt cttcaggttc cgcttctgtt tcttccggat
    35161 catgaaaaat gacacggatt ttaaggattc gagaaccttc catttcttca gaaaccagcg
    35221 taatattatc gacatcaaac gataactttt cgccttcatc cggaatcatg cctaatgctg
    35281 taatcaaata accagccatc gtatctacat cactcatatg cagatcactg tcaaaagctt
    35341 cattgaactc atcaatcagc atacgtcctt ggatgatata ttcgtgttca tcgatttttt
    35401 cataaagatt ctcaacttca tctgattcat catcgatttc tccgacgatt tcttctaaaa
    35461 ggtcttctag tgttgctaac ccaacgacgc cgccatattc atctaataaa atagccatct
    35521 gattctgcgt ctttttcatt tcatataaca gatcatcaat aaagaccgtt tcaggaacga
    35581 ataaaggctc ctgcatgatt ttcttgatat ctaaattatc aaagccgaat ttatgggcag
    35641 cttttagtaa attctttgta tgaaggattc cgactacttt atctttgtct tcgttataaa
    35701 cagggattct tgaatagttt tcggataaaa cttcattcac attttcttcc acagtgtcgt
    35761 tgatatcaat cataaatgca tccgttcgtg ggaccatgac ttctcgggca actttcgtat
    35821 caagagaaaa aaccccttgg agcatttcta attcttcatt attcaatacg ccttcgtttt
    35881 caagcatata acgcatttca tctctggtca tttttgaatc ttcatcatca aaagtcatcg
    35941 gcgtgatacg cgccaataaa cttgtggaag cagaaagcag ccagacgaag ggcttagcta
    36001 ctacaccaat caagcgtatc agccctgaag tgaactttgc gacttcttct gatttattta
    36061 aagcaatacg tttagggtac aattctccaa aaacaatcga tacataggtc aaaatagcca
    36121 gcacaatgat atttgcaata ttttttgccg ctgtgccgcc acctaatacc ggagctaacc
    36181 gttccgataa agtattagct agtgaagcac cagacaaaat gttgaccaaa gtgattccta
    36241 cttggattgt cgataggaaa ttatttggat tctgcaatat ttttaaaagc ttttgagatt
    36301 tcacatctcc ttcatcagct ttttgctcga ttcgattctt attgatcgaa acaacagcaa
    36361 tttcggaagc tgctaaaaaa gcattgatca atgtcaaaac gatcaataat aaaatctgcg
    36421 ctaacagcga ctgactctca gggtcagcat tcataatcgc attctctcct tataaaatta
    36481 atttttagtt tacgatagaa aaaaacgtgg cactatagcc acgttaaaat ggtatcacaa
    36541 agcaattttc tttgcaataa aaacaagtgt actaaaacta cctacgaggt cgtagcaatt
    36601 ttcttcttgt tttcattttg cttgtcttct ttgacgattt tgattatata ggaaatgatc
    36661 gtcttgcaga ttgcgtaaaa aggaacacct aagaagatac caagcaatcc ggcaatattt
    36721 ccagctacta gaagaacgat aatgatcgtt aatggatgga ttttcagtga tttcccaatt
    36781 acattaggat aaatgatatt cccatccaac tgttggacga ttagcacaac cacacaacaa
    36841 agtaatgctt ttaccggatc attgaagact gttactagaa atgcaggtgc tagtcctaga
    36901 taaggtccta aatatggaat taggtttgtc aatcccgcaa tgaccccaaa taagaaagca
    36961 taatccacac caattaccat atatcctaaa aatgtgaagg taccaacgaa taaacattcg
    37021 attgcttgtc cgctaatgta attagccaat gttttattca gttgccccaa taactccaca
    37081 atttggtttc ttcttttttc tgggaaaaac tgttggatgt ttggcactag tttttctccg
    37141 tctttcaaca tatagaacaa gatgaatggt gctgtaatga ttactacggt tgccgaagcg
    37201 atcgttccaa cgatcgaacc taaactattg gatactccac taaggaattg ctgaatgatt
    37261 gtcccgtaag aaatgtctaa ttgctcaaaa tatttattga tatctacttc cttgaacaaa
    37321 ggcaattcgg ctacctcttt taaccagctt tctacctgtt tgatgaaatc aggcatatta
    37381 gatgccaatg aggaaatttg ctgtactaga cttgggatga cactaagtaa aatccaaata
    37441 attgctgcaa ctaaaaggag cagcacaatt gcgacagccc atattctttt gatttttgct
    37501 ttcatcaaca gcttgacaat aggattcaat aaatagtaaa gaaagcctgc aatcagtaca
    37561 ggtgcaaata acgtggaaaa aaatgtcccg atcggttcga aaataaagtt tatttctgat
    37621 gaaatcatga tcaatgcagc tatgatcaat aattcaagcg accaaaacat tagtttagac
    37681 tgtctaagtt tttcaaacaa tagatttcct cctttctttc ttactagtat atattatatt
    37741 cgttaaaaat tcttttattc tttttttatt tttgaaaact tgccatactt tttatttgtt
    37801 ttattttcca gtatactata cgaaaggaag gtggctagac catgaaagtt gtacaaacaa
    37861 aagatacaat gagcaatatt tacttagatg ctgtacggat caggcatcaa gtttttgtag
    37921 tcgaacaggg tgtgcctttg tctcgagaaa tagacaaaga tgaagcccat tgtatccact
    37981 tcgtcctgta ctcagataaa aaagaaccgc aaggaactgt acgtcttttg cctttagaaa
    38041 acggaaaaat gaaattacag cggatggcga ttctttctga atacagacac caagggttag
    38101 gaaaaatatt gattgaagaa gcagaaaact ttgctaagaa tcaaggctat aatacgattt
    38161 tattaggggc acagtccaca gctgaaactt tttacgaaaa actaggatat acagcttacg
    38221 gcgatccttt tgaagatgct ggcatgcctc atatttatat gaaaaagact ttataaaaat
    38281 ttatttcgaa aaaagcaaaa aacagcaagc ttttgagaaa aatctctcac tggcttactg
    38341 ttcttttttg tgtttactta cgcgacaatt gcttgtaacg gttataccaa atatcaatat
    38401 agccttccga gaacgggcca tctccattat tgatccagtc aaccagaatc ttcacatttt
    38461 cttttaggat gaagtcaata tcgttcgggt aattcatcat tttgctgtgc atctcatatt
    38521 catcgacatc caatagtcgt ttctcgccgt caggaaatac cttgatatcc aagtcatagt
    38581 cgatatattt caaggcctca tcgtccagca aaaaaggtga agctagatta caataatagg
    38641 aaaccccctt ttctctgatc attgctatta cattgaacca gtatttttta tgaaaataaa
    38701 caatcgctgg ttcgcgcgtt acccatcggc gtccatcaga ttcagtgact aatgtgtgat
    38761 cattcacgcc gatcatagag tgttcgcttg tttttaatac catggtatct cgccacgttc
    38821 gatgcaattt gccgtcgtgc ttgtaacttt ggatcgtcac aaactctcct tcttttggaa
    38881 ctcccatagc aacccttcct taagcagcat tttgtgcttt gtgtttgggt gttcattaca
    38941 ccgacatcat aattattata tcaataaaaa tgagctttgc ctagaaagga ttcctattgt
    39001 ttcgattttt ctctaactga tctaccagtt tcatttggac cttaggaaaa acgaccgaat
    39061 caaatgcatc aggcttcaac cacttcgaag ttttgttctc ggtaaattct tgttctgctc
    39121 cctcggttgc ccgtccgtaa aaaaggagaa catgccattt cagatgacta aaaatatgag
    39181 taacttctcc taaatgtcgt gtctgccaaa caaagagttc ctgcttttca aatgggagat
    39241 tttgctcttc ttctgctact aggtcatcaa acagatcgat ttctggcttt gtttcccatt
    39301 cttttttcaa tcgctcatac tcctcttgtg tcacttccat cattggaaat gtccacatat
    39361 tcgccagcaa tttttggcta tctctttctt caaaataata cgctccagaa tgattttgaa
    39421 gagctgcact gatataataa acgtcttttg gctttgcttt ttttgttttt acaggaaaac
    39481 tcgtttggat tcctcgtttg ttagctaaac aaaaggcttg gatcggacaa gtctcacact
    39541 ttggagaagt tggtgtacag atagctgaac ctagatccat cattgcttgg ttgaattcac
    39601 ctggatgctt ttcatcaatg attttccgca tcgcttcatc aaagattttc ctgctagaag
    39661 cttttgcgat gtctgcttca atgcaaaaca atctgctgac tactcgcatc acgttgccgt
    39721 caactgcagg ttctggaagt ccaaatgcga tacttgcaat cgcgcctgtc gtatatggtc
    39781 ctattccctt caatgagcta atttcttcag gcgtttgcgg catttcccca tcaaattctg
    39841 acatgatctg tttagcagca gcttggatgt tccgggctct tgagtaataa ccaaggccct
    39901 cccatgcttt taaaagcttt tcttctggag catttgctag ctcttcaatt gtaggaaacc
    39961 attccatgaa acgataaaaa taatcgatca ctgtgtctac tctggtttgc tgaagcatga
    40021 tctcagagat ccagatacga taaggatcac gattatagcg ccaaggcagg tttctttttt
    40081 cttgttcata ccattgaatg aactgatctt gaaattcttt tgtttcttta tctgtccatt
    40141 tttcccattc tttattcact ttcctcttcc ttttccgtaa tgaatcgctg gatcatatcc
    40201 aaatcaaatc ctttttgata taagctttgc tttactttta gatttctttt tttaggttca
    40261 aaccttaaat ttcttcgcca tagtttatct ccttgtttga ctaaataatc atattctatt
    40321 tcttgatctg cttcttgcgg aagatcagct atcgcttgtt ggatcacttc ttgagaaaag
    40381 cctttcgtca tcaatgtttg ttggattttt ctcaataatt ctttttggct ttttccgtga
    40441 ttttttccaa acgctttttc ggctgtctga tgtgcatttt gaacttggtc ttcaaatgta
    40501 tattggctga gcgcttgttc aatgatttca ggtttcaaac ctttttgctg catctgctgc
    40561 gctaatttct ttggtccttt gtcacttaag cgcatattcg tgcgcacata actttcccca
    40621 tagaccaaat catcgacaag gtccaattct tttaagcggg ctacgatttt atttcgatct
    40681 tcttgaagga tttccttttc ttttaagtat gttcggattt ctttttccga tcgcaactga
    40741 taacttaagt aattcattgc taggtgaaaa ccgaaatcag ctccgctact cttcttgatc
    40801 tcttggatag tttcttcgtc taattcccgt ccttttaata atcgatagcg tactaataca
    40861 tcttcagata cttgtaaagc ttctccttca gataaatcta cgcgatagaa agggcctttg
    40921 cctttactga ttctcgtaac ggttaacata aacatcctcc tcgaacatat attctctatc
    40981 ataccacaga aaatccccgt aatcaggtat tatatgttag aataaaccac agaaaaaaga
    41041 aaaagggaga tacttatggc agaaacaatt gtcaaaactg gacaaacggt tcctttgaaa
    41101 atcaagcgtt taggcataaa tggtgaagga atcggttatt tcaaacggtt gatcatattt
    41161 gttccatatg cactaccaaa agaagaagta ctagtgaaaa tcacgaaagc aactcctcgc
    41221 tatgcagaag gagaattaat aaaagtcaaa aaaacaagca aagatcgcgt agtggcacca
    41281 tgtcctgttt actatgaatg cggtggctgt caattacaac acttagctta tcaagctcaa
    41341 ttggatttta aaaaggatct gcttttgcaa gcattggaaa aattcaaacc agcaggcttt
    41401 cgatcttatc aacttttgcc gacgatcggg atggatgagc cttggcatta tagaaacaaa
    41461 gcacaatttc agttacgaaa aaataagcag actcaaaaaa ttgaagctgg tttatacgaa
    41521 gcaaactctc atcagttagt ccctataaca gactgcttgg ttcaagaacc tcgaacacaa
    41581 aaagtaatga atactgttgt tcaactattg aataaatttg atgcacccat ctatgatgaa
    41641 cggacaaaca gtggaatctt ccgcacaatc atggttagaa tcggtgttaa aactggggag
    41701 ttacaagttg tttttattac tcgcagtaaa aaattcccgc aaaaaaacgc aatgatccgt
    41761 gagatcaatg aacgactgcc cgaagttgtt tcaatcatgc aaaatgtcca ggcacaaaaa
    41821 acgtctctcg tgatggggga tgaaacgatc cacttatggg gaaaagaagc cattgaagaa
    41881 caaatcaatg aagtgacttt cgatctttct cctcgtgcct tctttcaact caatcctcag
    41941 cagaccgaat tgctttatgg cgaaggaatc aaagcattag atgtccagcc taatgaaacg
    42001 atcgtggatg cttattgcgg agttgggacg atcggcttaa gtgtagcaaa acaagccaaa
    42061 gaagtacggg gaatggatac cgttcctcaa gcaatcgctg atgcaaaaaa aaatgcggaa
    42121 agattaggat atcacaacac tcgatatgaa gtcgggacag cagagcaagt tctgcctaaa
    42181 tggttgaatg aaggttttca gcctgatggt atcatcgtag atccaccacg tacgggtttg
    42241 gataacgcat tgatccaatc attattgaaa taccctccaa aaaaacttgt ttatatctcc
    42301 tgtaatgttt ctacacttgc cagagatctg gttaatttaa gtaaaaagtt caagattgaa
    42361 tatttacagt ccgtcgacat gtttcctcag actgcacgtt gtgaagttgt cgtgaagatg
    42421 acgagactcg ctgactaaat gaaagaggtt gtgaaaaagt ctgccctgta tcaagtaata
    42481 agaacagcca aacaaaaata gctcttcatg ttttatgaat actgtacttg tgaccgaaga
    42541 gttaacagga ggacactatt tatttaaaaa aagggttgtg acatagtttt tgtcacagcc
    42601 ctttttgatt attattggat attcacgtct atcacttgat aaaatgcatt tgtcgtatcg
    42661 ctgatattcc atactgctaa aatcacatta tatccttttc gatcctgcgg aagtgtgatc
    42721 gtttggttga ctgtttttgg tggaacagtt gctttgtcgt ctatttttgt gatcaattca
    42781 aaatcactaa atttcaaagg ttgattagga ttccaagttg gtttggtaat gtagtaatcc
    42841 caagtacttg tccgatgttg tgctgttaaa ttccaagtaa tatttaatgt tcctggatta
    42901 accatgtttt tatgccatct gttagatgtc tgttcatcta aaggctcaaa gccgctgact
    42961 cctgcactag caatttttcc atcaatgaat gtatttttgg tagcttcgat actttgcggt
    43021 tcccattgtg ctcttccgac attttgattt aagtttcctg ctgctgatgt tcctaggtat
    43081 gcacggcttc ctggagaagt aatataacca tgcgcaaaac ctggaatgct aaaaccgaac
    43141 aaccctaaac taactaaccc aataaacaat aacgtactaa tctttttcat gtagaaacct
    43201 ccttcatttg ataaccacat tgtaaacgct ttattgtatt aacacaaaca ttatgctttt
    43261 ataattttat gttgaagtaa aaaaggtgaa aaaagtaaga tgcagattat aacagaagta
    43321 gacgagaaaa gtacaaatag aaaacatgag aatcaaatca tatgatcttt ttcaaaaaca
    43381 tcattcatat aaacaaatgt tcaacttttt aataacaaca attatcaatt tttttcttac
    43441 ttcacaaact aaatacaggt cttgctgtga gccttcatgg taaactaata ttatagaaag
    43501 gagttagtaa aatgaagatg ataaaagata ttcgtttttg ggtttgtgtt ataggaattg
    43561 tcatattagg ctttttatca gggttgctta gcggaaatcc cggaaaatat tactattctt
    43621 tgcaacttcc accatttgca ccacctagct ggatatttgg gccgatgtgg accttactgt
    43681 atatattgat gggtatttct ctttatttgt tacttaatca caacaacaaa aaacagcgaa
    43741 acaatcttgt cggtcttttt gtgattcagt tcatttttaa ttttatatgg tctgctctat
    43801 tttttaattt aagaaatatt ttcattgcag caatcgatat tacactttta gttattttct
    43861 tgtcagtgct tatgtatcag ttgtggctgc atcatcgcct ggcaatgtgg ctcatgattc
    43921 cttattattt atgggtacta ttcgcaactc tattgaatta ttcaatttat tttttaaact
    43981 aagcgctaaa aagagacgtc ctgtaattta acacatagaa aaagtg
//
LOCUS       DAYYEF010000019        41819 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000019 DAYYEF010000000
VERSION     DAYYEF010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41819
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.019"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(281..373)
                     /locus_tag="ACHA1B_001202"
     CDS             complement(281..373)
                     /locus_tag="ACHA1B_001202"
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM8701980.1"
                     /translation="MPRRSFDEIFKITAVKLVTEEGFSVKEVSL"
     gene            complement(644..1624)
                     /locus_tag="ACHA1B_001203"
     CDS             complement(644..1624)
                     /locus_tag="ACHA1B_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HFM8701981.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(1637..2515)
                     /locus_tag="ACHA1B_001204"
     CDS             complement(1637..2515)
                     /locus_tag="ACHA1B_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HFM8701982.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(2531..3331)
                     /locus_tag="ACHA1B_001205"
     CDS             complement(2531..3331)
                     /locus_tag="ACHA1B_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HFM8701983.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
     gene            complement(3606..3755)
                     /locus_tag="ACHA1B_001206"
     CDS             complement(3606..3755)
                     /locus_tag="ACHA1B_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8701984.1"
                     /translation="MKKKVIPYCPKPRNAFERGLFKYFEGKKGQDHKEENQKKKSKKR
                     SEYIF"
     gene            4723..5049
                     /locus_tag="ACHA1B_001207"
     CDS             4723..5049
                     /locus_tag="ACHA1B_001207"
                     /inference="COORDINATES: protein motif:HMM:NF013698.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM8701985.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            5057..5965
                     /locus_tag="ACHA1B_001208"
     CDS             5057..5965
                     /locus_tag="ACHA1B_001208"
                     /inference="COORDINATES: protein motif:HMM:NF033542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFM8701986.1"
                     /translation="MCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSEKNRALNCLT
                     VSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEEIQAAVEGAI
                     SVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGLDTQPITAIA
                     ILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKPLLVQIANAL
                     LRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSAKGYLEPKPA
                     KEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            6591..6845
                     /locus_tag="ACHA1B_001209"
     CDS             6591..6845
                     /locus_tag="ACHA1B_001209"
                     /inference="COORDINATES: protein motif:HMM:NF013224.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HFM8701987.1"
                     /translation="MIKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESL
                     DSFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            7387..7545
                     /locus_tag="ACHA1B_001210"
     CDS             7387..7545
                     /locus_tag="ACHA1B_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8701988.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            7617..8842
                     /locus_tag="ACHA1B_001211"
                     /pseudo
     CDS             7617..8842
                     /locus_tag="ACHA1B_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(8931..9323)
                     /gene="rpsI"
                     /locus_tag="ACHA1B_001212"
     CDS             complement(8931..9323)
                     /gene="rpsI"
                     /locus_tag="ACHA1B_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HFM8701989.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(9339..9767)
                     /gene="rplM"
                     /locus_tag="ACHA1B_001213"
     CDS             complement(9339..9767)
                     /gene="rplM"
                     /locus_tag="ACHA1B_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HFM8701990.1"
                     /translation="MAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPTFTPHL
                     DTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLIETSVK
                     GMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(10301..10768)
                     /locus_tag="ACHA1B_001214"
     CDS             complement(10301..10768)
                     /locus_tag="ACHA1B_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFM8701991.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(10888..12426)
                     /locus_tag="ACHA1B_001215"
     CDS             complement(10888..12426)
                     /locus_tag="ACHA1B_001215"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046316 - gluconokinase activity [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA];
                     GO_process: GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HFM8701992.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            12506..13192
                     /locus_tag="ACHA1B_001216"
     CDS             12506..13192
                     /locus_tag="ACHA1B_001216"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="A24 family peptidase"
                     /protein_id="HFM8701993.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(13393..13920)
                     /gene="msrA"
                     /locus_tag="ACHA1B_001217"
     CDS             complement(13393..13920)
                     /gene="msrA"
                     /locus_tag="ACHA1B_001217"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFM8701994.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14004..14681)
                     /gene="pgmB"
                     /locus_tag="ACHA1B_001218"
     CDS             complement(14004..14681)
                     /gene="pgmB"
                     /locus_tag="ACHA1B_001218"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFM8701995.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(14678..15806)
                     /locus_tag="ACHA1B_001219"
                     /pseudo
     CDS             complement(14678..15806)
                     /locus_tag="ACHA1B_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(15806..17989)
                     /locus_tag="ACHA1B_001220"
     CDS             complement(15806..17989)
                     /locus_tag="ACHA1B_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 65 protein"
                     /protein_id="HFM8701996.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(17986..19011)
                     /locus_tag="ACHA1B_001221"
     CDS             complement(17986..19011)
                     /locus_tag="ACHA1B_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFM8701997.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(19056..19883)
                     /locus_tag="ACHA1B_001222"
     CDS             complement(19056..19883)
                     /locus_tag="ACHA1B_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="HFM8701998.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(19880..20947)
                     /locus_tag="ACHA1B_001223"
     CDS             complement(19880..20947)
                     /locus_tag="ACHA1B_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HFM8701999.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(20973..21809)
                     /locus_tag="ACHA1B_001224"
     CDS             complement(20973..21809)
                     /locus_tag="ACHA1B_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702000.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(21806..22675)
                     /locus_tag="ACHA1B_001225"
     CDS             complement(21806..22675)
                     /locus_tag="ACHA1B_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702001.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(22745..24028)
                     /locus_tag="ACHA1B_001226"
     CDS             complement(22745..24028)
                     /locus_tag="ACHA1B_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8702002.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(24042..25727)
                     /locus_tag="ACHA1B_001227"
     CDS             complement(24042..25727)
                     /locus_tag="ACHA1B_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase family glycosyl hydrolase"
                     /protein_id="HFM8702003.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            26002..27027
                     /locus_tag="ACHA1B_001228"
     CDS             26002..27027
                     /locus_tag="ACHA1B_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8702004.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(27622..31275)
                     /gene="rpoC"
                     /locus_tag="ACHA1B_001229"
     CDS             complement(27622..31275)
                     /gene="rpoC"
                     /locus_tag="ACHA1B_001229"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HFM8702005.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(31354..34971)
                     /gene="rpoB"
                     /locus_tag="ACHA1B_001230"
     CDS             complement(31354..34971)
                     /gene="rpoB"
                     /locus_tag="ACHA1B_001230"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFM8702006.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            35699..36667
                     /locus_tag="ACHA1B_001231"
     CDS             35699..36667
                     /locus_tag="ACHA1B_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8702007.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            36685..37590
                     /locus_tag="ACHA1B_001232"
     CDS             36685..37590
                     /locus_tag="ACHA1B_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702008.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            37587..38393
                     /locus_tag="ACHA1B_001233"
     CDS             37587..38393
                     /locus_tag="ACHA1B_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702009.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            38550..39518
                     /locus_tag="ACHA1B_001234"
     CDS             38550..39518
                     /locus_tag="ACHA1B_001234"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004077 - biotin-[acetyl-CoA-carboxylase]
                     ligase activity [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HFM8702010.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(39835..40359)
                     /locus_tag="ACHA1B_001235"
     CDS             complement(39835..40359)
                     /locus_tag="ACHA1B_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HFM8702011.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            40646..>41819
                     /gene="scm"
                     /locus_tag="ACHA1B_001236"
     CDS             40646..>41819
                     /gene="scm"
                     /locus_tag="ACHA1B_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFM8702012.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTD"
BASE COUNT        12062 a         8806 c         7685 g        13266 t
ORIGIN      
        1 taaaaaatat gcggcgcaca gaacgcgccg catatcggac taagttttat tcaaatttgt
       61 cttcgccaac acaatttgac gaagagcctt ttctttcagg aagacttcgg taatttttag
      121 gagttctacc tattctttta accgtttatt ctctttttct aagcgtgtaa tttcatttct
      181 gcgaatggat ttcatgactt cctctaccga gaaaagtacg ttatccatat ttttcaactt
      241 cttgaactca tcaatacacg ctattagagc gagcttctag ctatagacta acttctttaa
      301 cagaaaaccc ttcttccgtt accagtttta cagcggtaat tttaaatatt tcatcaaatg
      361 aacgtcttgg cataatccag atcttcgctt tctcttaatt tggtgtcaat tttagtataa
      421 cccgtccaac ttatttttta actaagtgcc cggtttttct tgacaactcc acccaaaagt
      481 tagatttttt ggtctaagtt ttagggtcgc ttcattacta gaattcaaca agagatgttt
      541 tttattttat ttaaattatg gggtcagttt ccatttgatt acaaacttct ttgttttctt
      601 tttttaaacg caataataaa ggttttaatt tcagcctttt taattagaaa atcaattttc
      661 ccaaattatt ttctttagct ttcttaacga tttctgtcgc aactaccaca tctaatacag
      721 ccgaaccaac tgttttgaag atcgtgattt gttctccact tgtccgaccg atcaattctt
      781 cattgatcag ttggcctagt tccccatgat agctgtctct ttgaatatac ccatcttgca
      841 gcggtgaaat gaagtcccca gcttctttta gaacaccgtc catggtatca aaaataacaa
      901 catctgcggc tttgattatt tctcgtggaa tttcacacat ttccggtgtg taagcaccga
      961 ctccattgat gtgcgcacct tttttgaccc actcagcaga gaatgtcgca cgttttgaag
     1021 tggtcacact tgtaatgatg tctgctcctt caacgcattc ttgactggtt tttgttgggc
     1081 gcatcgttac agaaaattgt tgcatcattt tttcagcaaa ttggctggca cgctcaaaat
     1141 caatatcaaa aatccgaact tcttctaatt tacgaacggt caacattgct tctaattgtg
     1201 actgtgcttg tccgccggtt ccaatcagcg cgccaatttt agcatcttct cttgcaagaa
     1261 gttctgttgc tgctccttga acagcgcctg ttcttaattg tgtcaaataa gtaccatcca
     1321 aacaagcgga taccataccc gtttctggat ccaatacgat catcgttgct ggtacacttg
     1381 gtaagttttt cttgatgttt tcaggataca cggaaacgat tttgacacct agcgcgcctt
     1441 cgccaccttc tacataagca ggcatatata agctttgtcc gttgcttttt ggcacatcga
     1501 tattggtgcg aagaggcaca cttgcctttc ctgctgaata caatgacagt gcttttttgt
     1561 ccgcatcgat ggcttctctc attgaaaaac ttttgataat atcttctttt ttaagaaata
     1621 acatttgaat cgctccttaa ttagctgctg taactttttt taattgactg cccaacatcg
     1681 tatatgcact gtatagtaag accaaaatca cgatccattt caggatatag gtatctaaag
     1741 atttgactag gaatacagcg accaataccc ccaatacacc gaaggttgaa gtaaaaagtg
     1801 tgatttttct gctgtattca ttaaatttaa tgaattgaac actgccgatc ggtactgaga
     1861 aggtacaagc ccccatcata ataggaaagg ctgcaactgg attcaagcct agcaagtaga
     1921 cagttaccat cgttaacgca taagaaccaa tgccgatatt gttcaatgca ccatagacaa
     1981 agagtaaaaa tcctgccaag attaattttc cgccatacaa ttcactggct gttccgtttg
     2041 atggaatcca gttcatttgt cctgcaaaaa tcaacaatgc agcaatgacc aatcctatgc
     2101 cgacaaacag tttgatcgtt ttctctggta acttcacgac aaatcttggt cctaaatatg
     2161 caccgataat ttggcagata atacaaacag ctagtgtctt gatccctacg ttgatggcag
     2221 tgatgtaaga caatgccatg acggctaccg gtactacaca ttgggtattc aacgttccgg
     2281 gtagtttttt catgctgacc catttcaact ttggataaag gacggttccg atagcaaagt
     2341 cggaaacgcc aaatgttgaa agaaagaaga tgataaatga cgtgaagggc aacagacgca
     2401 tatcccctgg ttcttctttg aaattttgtt tgtttttgaa aaggtctctt agaaagtaaa
     2461 taataaaata tagattgatt gcgacaatta gtgtcagcaa aatattccga atcataaaaa
     2521 attcctccta ctagtaaatc tttctgattc cctcaaagcc ctcaccatat tttgctttaa
     2581 gttcttcagg agattctgca atcactttta gtgtatatgc atcatgtttg acatattctt
     2641 ttgctagatt gaccatggcg tggttttttg tccaagtgac atcggttgat tgcagttctt
     2701 cgttaatggt accaaacacg acttcttgct catcggcgac gatgttgatc catcttgctc
     2761 caaagtcagc aagtttgtct gtttcaaaac catgaatata atacttttct aagggaagat
     2821 catattcatg ggtagaactg aataaaatca gtacaaactt atcaactctt ttttcagctt
     2881 gctgcaatgc ctttagtagt gaatccgtga aattctcatg ccaaacttga atgagcaaac
     2941 tttcttttgc gtttttcacc aaatgctcta ctttatccag aacatactcg ataccatcaa
     3001 ctttccacag catttcttct tcatcttttt ctttgatcat ccctagattc ttggtaagaa
     3061 aagaaagatc atttttaaca cttttttcta atttctctaa aaactcattt gccgagatgg
     3121 catgataaag tttaggttct gatttattaa cgacaatcaa attctttttt aatagttttt
     3181 ccaaaatatt atatactttc gagcgtggca cacctgagat tttacttact tcatatcctg
     3241 taagattacc tttttctaat agtgtggtat acactcttgt ctccatctct gaaaaatcat
     3301 attttttcat gatttgaata atcgtttcca ttgattaatc ctcactttat ttttagtagc
     3361 tactacggta acaactataa attctttttg attatctgtc aagagttagt tcaataacac
     3421 acatataata attagcttaa aaacaatctt tttattaaaa agaaacatta taatatgaat
     3481 gtttgtgaaa aaataataca acttagtcat tctttacaac gatttataga aaaacaacct
     3541 ctttaaatat aaaaggtacg ggttactgat tacttgtaaa tctttacgtt ccagttttat
     3601 tctttctaaa aaatatactc acttcttttc ttagacttct ttttttgatt ctcctcttta
     3661 tggtcttgtc cttttttgcc ttcaaaatat ttaaataaac ccctttcaaa agcatttcta
     3721 ggttttggac aataaggaat gacttttttc ttcatataaa tacctcattt aactatttga
     3781 tatcatcaca ttatcaaaaa aaataggttt tttattaaaa ctatcttgac ctttcgggag
     3841 atttcactgt gatttatttt tattcccata cttttttcgt tggtcacttt cgtataccta
     3901 atctaagcga tcatcggcga cggtgctttt acaacgaatg gcaggacaaa acaaggggcg
     3961 gaaaaacttt tttgcctatt tcataaaaaa ctttttccta cagcaatccc ttgttttgtc
     4021 ctaccacacg ttgtgaaccc aaagcacgcc gacgaacgct tagctatacg aaaatgacct
     4081 ccaaaaacaa aaaagtgagg tgaatagaaa caaaaagaaa ttgaaatctc ccaaaatgtc
     4141 gtccgcctcg gagacaactt gctgctgaaa atggttggtt aattcattta agtattaaat
     4201 aagataaatc atcaaattaa tcggaaaaat agcatgattg gccttatcaa aaataaactg
     4261 taaaaactta tatttctatg agtggtggaa caatgctaat accaaattaa tttatcgatt
     4321 acccacctgc acaaaccaaa gatagcatta ttaggaaacg aatcaatcag cgaatccagc
     4381 attataatga ggatactaaa aataaagttt tcataattat aaatccgcct tcctacgaaa
     4441 ggcaccaatg aggtgatgaa aaccttagag cgctttcttt ctttttttat tccgtgttac
     4501 cctttccttg caggtccctg gtacactaca gaacccgagg aggtgagtgg cggggctgta
     4561 tagcggcaac cccgcataat tatatggtgt cggtcatccg ttaaggcatc aatgaatggc
     4621 gcaaacccgt agcccgtaaa cttatctctt ccgaagttga ctcgatttcg ccggatgacc
     4681 agtccctacc aaacctgtac tattttttta cagaaggttg ctatgttcaa aatctttcgt
     4741 aaaaattgtt gtggcttgga tgtccacaaa acgtggatct atgcgtgtat cggaatcaca
     4801 gatgcgaatg gtcgtacagt gtataagcaa gctcgcttct cttcctttac aaaaggtctc
     4861 aatgaattag ctgaatggct tgctaaatac aactgtaagg atgtgtgttt ggaatcttcc
     4921 ggtaaatttt ggattcctgt ttttaatatt cttgaaaaaa cttgttttgt cacactggct
     4981 catccgaagt acaccaaacc ccagaaagga aataaaacag atcgcaaaga tgcaaaaatg
     5041 gatttgtgat ctctttatgt gcgacatgat caaacccagt tttattcctg gtcttgaaat
     5101 ccgccagctt cgtgatctaa tgcgttatcg gacgaaactg accaacatga aaacaagtga
     5161 aaagaatcgt gctttaaact gcttaaccgt ttctaatctg aaactagatg atgtttttag
     5221 tgatgtgttc ggaaaatcat ccacttctat catccaatac ttgttagaac atcccggtga
     5281 atcatttgat gttcgaccat ttatccatgc ccgttgtaaa actcccgttg aagaaatcca
     5341 agcggcagtt gagggggcga tttctgtacc tcaagcgatt aagcttcgcc aatgcctcaa
     5401 ccatattaac gagattgaga agcatcgaga agagatcaat ctagagattc aagctcttgc
     5461 agaacccttc tcccctgttt tggaactact tcgtaccata ccgggcttag acactcagcc
     5521 aataacagcg attgcgattc tttcagaaat aggaccggat atgtccgtgt ttccaacttc
     5581 gaaacacttt atttcttggg ctggatgctg tccaagaaac gatcgcagtg cccgacgaac
     5641 aaaatcaaca cgtatctctc gtgcagggca gtcgttgaaa ccgctacttg tacagattgc
     5701 caatgctctt ctcagatcca aagaacatcc agaatttaaa aatcgctatc gtagaatcaa
     5761 agcgaatcgt ggacacaaga aagctatcat tgctatttgt aagatgctcc tgaccgctat
     5821 ctggaatgtc ttatcaaagg tggaacccta ttctgctaaa ggatatctgg agccaaaacc
     5881 tgcgaaagaa gagaaagttc tgacgcaatc ccaagctctg gaccttttaa gaaaacgcgg
     5941 atataccatt atagatagtg cttaaaccaa agttacgttg attcttccta aatagactcg
     6001 ttgtcttcca tttcaaaaat tttgaaaacg gtaggcttat ttagtgtacc gttcttcagg
     6061 tatcttcaaa tagatttatt ttcaaactta tttcctttct tcttttactc tcctatagct
     6121 tagcatttaa gtgggcactc gtgtcacctt gctagatagc tatgaatgcc gtaataagcc
     6181 tcctagtata taggcagact gccaattata actgattcaa tccacattat gataaaatcc
     6241 accttttcgt ttcatatgtg ttgaaatatc acatatgtca aaagtgcacg agtcttttca
     6301 ttcagtgctt tgtaaatact caaaattatt ccttttcact ttaaaaaaaa gataattagt
     6361 acaaaatcag aaatgaggaa agtattagga tggactagaa aggagttgtt gaatttgttg
     6421 caacagattg gtcatttatc aattaaaaat taggtgaagt tttattcatc actgcagctg
     6481 ctgtttccca gagaataaaa cgtctagaag aaactggtca gttactgtat tatcaagcag
     6541 caattgacta cgaacaagct tgattactaa ccaaagcgtt tatccacctg ttgattaaat
     6601 caaatcaaaa atcaggtttt tatacgttca taaaagcaat ctccagtgta ctcgaatgtg
     6661 actgtatcat aggtccttat tcgatgttaa tcaaaatggg gtttccttct accgaatcat
     6721 tggacagttt tatcaatgat ttatcaaagt ttggacgaac caacacccaa atcgttttct
     6781 cgactcttgt ttccttaatg gtttatcagt tctggaatgt ttatcatgcg cttttattaa
     6841 aatagaaaag agcttttttc atgcgacaaa gcagtgatca tttattggca catgcaatct
     6901 ttgtggatcc attttttgaa aatacgatat ttagttttga cccaaaaatc tttaaatacg
     6961 tatttgataa tttatcttaa caaccagata attttattca gcaccgtatt atctatattg
     7021 aattctcgga atcaagataa atttttttcc gtttttgttt cttttttaat cttcttcttg
     7081 ttattaatag tgattaggat gatattccta tattgatctt tgataattag atataatttt
     7141 tgaataacgt tccctgctat tcgagctaga aatacaagta cgccatgacc tagttagcga
     7201 caactactta gagatttctt ttgttctggg acaacaaaat gccatgacaa tagcagtaaa
     7261 taatgatact tccgtaaggc tcgccgtaaa ctggggagag gtgaaattcc tatgtgctta
     7321 cccaaagcgg ttcaaaaatt ttaaactatt attttaggag atgattttat aaaatcgaaa
     7381 gcctacttga ataaaaaaca agcctgtgaa tttctaggaa ttgataataa tactttagat
     7441 aagtggattc gtgtatataa ttttccagta ataaaaattg atggcgtagt tcgctttgac
     7501 gtagaggata tcaaagattt catgaataca ttcaaaaaaa attgaaattt tcttctcgtc
     7561 acatatacta taaatagcga aatgtactgc cttacttttt aaaggagtga ggaagtttgc
     7621 ctacaaagct ttcaaatggg aaatataaaa ctaatctgag gtatccaaaa aaattcagag
     7681 aaatcactgg aattgcatca gagaagtatc aaaaagtatt tccaactagg caattagcta
     7741 ttaaggccga aagggaaatg aaaaagaaga ttgaaacagt tttaagagag gagaatgcaa
     7801 actcactaga attgaaagga aaaataaaat ttaaagattt ttatgaatca aaatggcttc
     7861 ctagatatga actaggtcaa actactaggt caaacagggc tccaagtaat gtaacaatta
     7921 gtaatactaa ggatatattc cgattgcaca tccttccaat gtttggtgaa tatgcaatga
     7981 attatctgaa ttcaaatact gagataatat cagatgaatt aacaaagaaa tcgaaagaat
     8041 acgcaaatat aaaaattatc aaaggctatg ttcgctctat gtttgatatt gccgaaatac
     8101 tatgttatat cgaattcaac cgaactacca aaattattca atgtattacc gcgcctaaga
     8161 aaatggcttt agaagaaaaa aggataaggg aagggaatca agcattatca tcagaagagc
     8221 tgactgattg gatagaagca gtaaacaatg acttaaataa tcacttgctt acacttcacg
     8281 attacacact tttcatgctt accttatatc taggtgatag aaaaagtgag acttatgctc
     8341 tgcaatggaa atatattgat tttaataaaa atacggttcg tctcaaatat gctttagata
     8401 aatatcaaag aaagacacat acaaaaggtt ggaaagacac cgttattcag gcaccagaag
     8461 ttgtgatgac attattaaga gaatggaaat cagctcaggc tgaacaattg ttgaaactaa
     8521 aaattataca aacacctgac cagtacctct ttacctattc caaaccttct ggagaagtaa
     8581 attgtcctgt tcacgctgac tacttaaact atcgaatcaa tgcaataaaa aaaggcatcc
     8641 tgaattggct caattatctc cacacaaact tcgtcatacc tatgcaacta tagctaggga
     8701 aggtggagca aatatgaatc aaatctctaa tgctttaacg cactcggata tttctactac
     8761 aaaaatatac gtgaacacac ctgacgtagt tgataaatct gtttttgaag catttcaaaa
     8821 aggattgaat aagtgtgatt aacatgtgtt ctcaaatgtg ttcttattat aaaaaaagac
     8881 actttccaaa taattgaaaa gtgtcctgaa atattgatat aaaaagaata ttaacgtttt
     8941 gagaattgtg aagctttacg agctttttta agacctggtt ttttacgttc gaccatacgt
     9001 gcgtcacgag taagtaagcc agcacgttta agagctaaac ggaagtcagg atcaacttct
     9061 agcaatgcac gagcgatacc atgacggata gctcctgatt gtccagcgta tcctccgccg
     9121 tttacgttaa caaatacgtc atatgcgcct tttgtttcag taacagcgaa aggttgattg
     9181 attacttcac gcaagtcagc atgtggaatg tattcttcaa catctttttt atttacagta
     9241 attttgccag ttcctggtac tagacgtacg cgagcaactg cgtttttacg acggcctgtg
     9301 ccgatatatt gaacttgtgc caatgaaatt ccctcctatt agattaagtt tgtgatgtct
     9361 aaaacttctg gttgttgtgc tgcatgtgga tgttctgctc caccgtatac gttcaatttt
     9421 gtaaattgtt tgcggcctaa agtgttttta ggaagcatac cttttacaga agtttcgatc
     9481 aaacgacgag aatttttagc acgcaattcg ccagcagtga ttgatttcaa tcctcctggg
     9541 tagttgctgt gacggtaata aattttgtca gtcgcttttt tacctgttaa tttcactttg
     9601 tctgcattga tgacgatgac gaaatcgcca gtatccaaat gaggtgtgaa agttggttta
     9661 tttttaccac gtagtacaga tgcaacaact gttgaaagac gtcccaatgg aacatcagtt
     9721 gcgtctacta cataccattt acgttctact tcgcctggtt tggccatata tgttgtacgc
     9781 acgttatttt cctccaattt aagttctgat gtttgacata cacttcgagt ttccggggct
     9841 ctttgtgggg caaacaatac catttaacat attacccgct aatctagtca atgtcaacgt
     9901 ttttctgctt gattgaaaaa tttatatgaa actttacttc ttttctttct tttatataaa
     9961 agggtcgttt cctgtcaaaa tgaaaaacaa aaagaggctg tgacaaaagt cttgtcacaa
    10021 ccccttattt tgaataaacg gtgttctcct gccaactcct cggtcacaag tcacaatatc
    10081 cataaaacat aagaagctgt tttttaaaat tgtttcttgt gactcggagc tgaacggcag
    10141 gcttacaacc tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa
    10201 cggcaaaata tgaggaacta ttttgacgtt tgtttctcta atactcaggt caaaacgctg
    10261 atttcacaac ctctttttcg gtcaagttca acaacagttt ttacgcgtcg atctctggcg
    10321 ctttgcccaa atgagcttgg atcatccaga tacgtttttc tgtggctgtt ttgaattcga
    10381 taaagatatc ttgtgttgga tcgtcgcctt cttctccaga aacttcgatt cctttttggt
    10441 aaagatctgc tagataacga tagcctgcaa caagtgtttc caaacgttct ggaatagtac
    10501 gatcccagcg gccaatttca tcagggattt ttgtgttatc tgcaaattca cgcaatgtag
    10561 aataaggtga accgtctaat gtgatcaagc gttcggatac ttcatctaac tgagcgttca
    10621 aatcatccat gaactcatcc atcattgggt gcaatgtaag gaaacctggt cctctcatgt
    10681 accaatgtgt ttggtgaaca acaacagaca tttggcttag atctgcaact aattgattta
    10741 atacttcttt ggtttgttgg aatttcatct ttcttgcctc ctaacatttt cttacactta
    10801 aaataatagt agactttcaa tgaaaagtac aacaaaatca tttacctgag aacgattttc
    10861 agttcgcttt tttatccgta aagccaatca tttttcagaa tcagctaatt cttctcgcag
    10921 ttgagcaaat tgctgataag tctgtgctaa atgcttttgt gtcgaaacaa ataatggata
    10981 gattttctga tattttttat gatcagtttc ttgtactcca acttgctctt tcaattctat
    11041 caattcctgt gcttcactga tactttggat ctttccgatg cttctccagc ctaaaatcac
    11101 agctcctaat gcggatgctt ctgtgacagt agggaaaaca agcgggtaac ccagtacatc
    11161 agccatcatc tgacgaaaaa tcggagattg agcaaacccg cctgtagcac ggatctctgt
    11221 gagctgattt tcctggcaaa ctccttttaa aatccgataa aggttgagac agatcccttc
    11281 tagaatcgcc ttcatcattt ctttttctgt atgttgccgc tgtaaaccga taaaactgcc
    11341 aaacgcatct gcgtcccaaa gcggtgctcg ctcaccaagt aaatagggat gaaaaatcag
    11401 accattggca cccgctggca caaaagcgat agccgaaagc agtgcatcat atggattttc
    11461 tcctttttct ttagcagatt gaacgacttc ctgtaaaaat gtatgccctg cccaatcaaa
    11521 gatgccagca ccattgctag tcgctcctcc cactacccaa tgtttctgat ccagaacata
    11581 acaaaacgtc tccatttctg gatggaactg aggctgagta gtaataaaac gaagtgctcc
    11641 gctcgttcct acggtcaaag cggcgatcgt atcaccaaaa gcacctaacc ctagattaga
    11701 aagcggcccg tctgcccctc ccaaaacaaa tgatatatca tttggcaaac ctagttctgc
    11761 tgctgttttt gatggtagac ctgttacttg ataggtggaa ggaaagactt gcggcaattg
    11821 ctctattcga atgttcaagt agtcaagcac ttcttctgcc cattggaatt catggatatc
    11881 aaaatatcca gttcctgaag ctgttccgta gtcgctgatc agttcgccaa acaatctata
    11941 aaagatatag tctttgatac cgacaaaata agcagttttt ttgaataatt caggttggct
    12001 gttttgcagc cacttgattt tgttcaatgg tgtcattgga tgaatcggcg tcccagtctg
    12061 ccgataaaat tctttgccaa gcacggtata tttcagtttt tctgcttcgt ccgctgctcg
    12121 gttatctgcc caagtgatca ttcgagataa cggtgttttc tcttcatcca acaatatcag
    12181 gccatgcatc gcagaggaga aggagacaaa ttgaatgatt gtgtctgaag gcaactgttt
    12241 aattacttct tttataacgg tgcagacacc ttgaaagatc aattcctgat cttgttctgc
    12301 catcccttgt gtttcttgga tcaaagggta gcgaaaataa gcggatgctg cttcttgggc
    12361 ttcatctgtg aaagcaactg ctttggtttg tgtggttccg atatctaatc cgattgaaac
    12421 gttcattttt tcacctcaaa ttttatgtat gtacaaaaat ttagtttaag cttgcgtatc
    12481 ttggttttga aaagggggag atggcgtgtt actttatttt atcattggtt gctgtatcgg
    12541 atcattttta tgtttaaccg cccagcggat tccgttaggt cactctatta tttatcctag
    12601 atctcattgt gtcaaatgct gtcgttcgct ttcttggtat gaattgattc cgattctctc
    12661 gatcatcgtc caacgatttc gctgccgcta ttgcaggtgt cggttgccct tctactattt
    12721 gttggcagaa gccttatgtg gtggtctttt tgcctggttc tttacttttt cttccgcaag
    12781 aaatttttcg acgttcatat ggatgctttc ggctttgcta ttttcgttga tggatttatt
    12841 ttacttcatg gtccattctc acacgctatt ctgttcttgg gcaattttat ggattttttg
    12901 gttgcaggcc ggcgtcttcc aatggcaaag tgtgctgtta acgtttatcg taggcggtgt
    12961 gtgccttcgc tatggtcaat cctatctcgg agctggcgat actctgttga tgctttcttg
    13021 gagtggtggc ttgtctctag aagagttgct tcagatcttg tttcttgcta gtctgtttgg
    13081 aatatccgtt ttttctgttt actttatctg tcataaaaaa aagttggaaa agctgccttt
    13141 cattcctttt ttgagcagtg cgttgctgat tgtccttcat cttaggtatt gaaaaaaggt
    13201 tgtgacaaac gacttgtcac aacctctgat atatagtgtt ctcttaccaa atccttgtga
    13261 cttggagcta ggcgacaggt tcacaacctc tccactaaat ggtgttcaat cagctgaccc
    13321 tcagtattag ctcaaaatgc tggttttaca acctctgata tacggtgttc cataagtagc
    13381 tttttcggct tcttatttct tgacgcccca atgtcgacga aggaaacctg cacgtccaga
    13441 accttctcga taaagattgt aatggagctt gtttttcttg taataatcct gatggtaatc
    13501 ttctgcagga taaaattcgc ttcttggttc gatttttgtc acgattggct tatcgaatcg
    13561 cccgctgtct tgcaatgctt gttttgaacg ctctgcaata tttcgttctt cttcatcatt
    13621 atagtagatc actggacgat aagaatcacc gcgatcagcg aactgtccta atgcgtcagt
    13681 cggatcggtt tgctgccaat agatttccac caactgatca taagaaataa cttctggatc
    13741 atattcgatc tctactgctt ctgtatgccc tgttgtgcct gttgttactt gttcataagt
    13801 tggatttggt acatgcccgc cagtataacc ggatgtcaca gaaatgatcc ctggctgctc
    13861 ttcaaatggt ttgaccatac accaaaagca tccgcctgcg aaaactgctt tttttgtcat
    13921 ataaaatccc ccttttttct catcatacct tgatttccaa aaggaggata acgttttgct
    13981 tgtgacagaa aaaacggaaa ctattatata cgtgatacgg cttctgataa atgccaaaac
    14041 gaacgtactt gatcaaaaac ggttaaatca ggaatcacat attcagcaga aggaagattt
    14101 atgttttcac ctattcccaa tacatgcatg ttaccagcca aagctgcttg acaaccagct
    14161 tctgaatctt caatgaccaa gcatgcattt ggcggtacat tcaattgctg tgctcctttg
    14221 agaaaaactt ctggatcagg ttttgctttt gatacttgcg tgccgtcaat aaggacatca
    14281 aaataacttg tcaaattcgt tttttctaaa atgaggcgtg catttttgct tgctgatccc
    14341 aatccgatct tgatgtttgt ttttttcaag tactcaagaa cagctattgc accaggcaaa
    14401 acggatgttt catccatttt ttgaatcgct tgaagatata gattgttttt ttgctcagca
    14461 aaggctgatt tctctttttc tgagaatttc tgttccattt ttccaaatga cagcaatcgc
    14521 tctagtgact cggttctgga tattcctttc agttgctcgt tttctttctc agtgaatgga
    14581 atggacagct ggttagctaa aaccagccac gcttcgtaat gataacgagc tgtgtctaca
    14641 agaacgccat ctaaatcgaa tagtgctgct ttgattttca tcgattacct ccttgaaaat
    14701 gaacgacttg aagtaaagat gcgatgtttt tagctgtgcg atgaagatta tcagtggctt
    14761 gctgtaaagc ttcttgtaaa ggcacagctg caggaaggat cggaaaaacg gccgaaatgc
    14821 caacatctgc tgctttttcg cttcctttac caacacttcc gcaaatagct atcacaggaa
    14881 cgccctctgg tactcttcta gcaatcccaa ctggcgcttt tccttttaga ctttgtccat
    14941 ctagacgtcc ttcgcctacg attacgaggt ctgcttgctg tacccgtatc gaactccagt
    15001 aaatccaata cgtagtcgat gccagagact attttccctg aagcaaatgc taacagtcct
    15061 gcacccattc caccaccagc actactgccc gatgcctcga ttacttgagg ggcaaatctc
    15121 atataaaaat catgcatggc ttggtcagcc actgctaatt cattttcttt caagcctttt
    15181 tgtggtccga aaacaaaaga agcgccttct tttccgcata aaagattagt aacatcagta
    15241 atgacagtga ttttggcttt aatcagctca ataggcacgt tcgttttatc aactgtagca
    15301 attttaccta gattttctcc cagtgcttct actttttgat tatcttgatc gtaaaaagca
    15361 taacctagac cttctgccat gccgatgccg ccatcgttgg tactacttcc gccaacgccg
    15421 atgatgatgt gtcgaacacc ttgttgcaac aattgtcgta tcagttctcc tactcctcgc
    15481 gtggataacc taagtggctg ttgttggttt agtgggacat ctttcaatcc gacgatttct
    15541 gccatttcaa aaatcgcagt ttgaccgtct gaagcgtact ggatttcttt gtttttgcca
    15601 aatgcattag taacgactgc tgtttgccgc ttcaacctta aactgtctgc taatgatgaa
    15661 accgttcctt ctcctccatc gcctataggt agcagatcat attcagcctg aacaaaaact
    15721 tcttgaaaac ctgattgaat ggcttgtgct gcctctaagg ctgtcagact ttctttgaaa
    15781 gaatctggcg caatcagaat acgcattatt ttcccctccg ttccaagatc agttcttttt
    15841 ccagctggta ttggtctcca ttgacaaaaa taggtaatgt ttctttcgtc tcttttttta
    15901 ttactatttg tttttttgtc aaaacaaata gcaacctgtg atttttccaa ataaaaggaa
    15961 aagaaatttt ttcccatgct gaaggaagtc ttggagaaat agaaagagtt ccattcgtta
    16021 ctgtaatacc tgaaaaacca aatataactg ctagccatag tgctcctaat gaagcagcat
    16081 gaattccgtc atctgatgaa tgcggatctg gtcctaaatc aatcaggcac gcttcttgga
    16141 ataaatgata cgcccattcc atttcttgga tacggcaagc ctctatggcg tgaatcgctt
    16201 tactcaacga tgagtcgtgg attgttttgt tttcatagta atgcaaattc ttagaaacga
    16261 ttggttgaga aaaatactca ggtaataagt ataacagcat gacaagatct gcttgcttgc
    16321 tgacttggag ttcatttact tcgctacggg cataatcaag taaaatagac tggctgccag
    16381 gacgttcttt gtaagtggtc aaatcaataa ctggcttact gagatacgtg tcatcttgcg
    16441 gaatcagctg ttctttgtta ggcactggca aatataactt atctaaaaaa ttttgacatt
    16501 ctttcaaaaa aagcggatcg ccagcttgat atttaacagc taaggccaca ttataatgcg
    16561 ccagatagtt cgtatatgca ttattgtcga tatattctgt gtattcatct ggaccaatga
    16621 ctctgtgtat ctctaaatga tcatcgactt ttacagctct gctcagccaa aaagctgctg
    16681 tttcatgaat gagcgttttt ccctttgttt ctaaaaacga ttgatcctct gttgcttgga
    16741 catactcttg aacggcataa gcaaggtctg cactgatatg atgttctgcg gcagctgaag
    16801 caacttcttg tcttgttccg gttttgatat tcaatgcagc aaatttgggt gtctcttcct
    16861 gaccagtgtg tgcgctttcc catgggaaaa gtgcaccttg atagtgataa tctcttgctt
    16921 tttgccgtgc gccttctaat cgatcataac ggtacagcag caaattcttt gctacttcag
    16981 gaaactgata taaaaagaaa ggcaggataa aaatttccgt atcccagaaa acatgccctt
    17041 tataaccttc gccagttagt cccttcgccc ctacactaac acttggatca ttgcggggag
    17101 tcataatctg taaatggtaa gcagcgaagt ccatcgctaa ctgatcgaaa gaagaatcgc
    17161 cttggatcgt tatccgatgc tgatgccaaa aatctgtcca ataagacatc gactgctcta
    17221 aaatttctgt ataactaacg cttttctggg cttgggcaat acttttctta aacgggtctg
    17281 tttgctgaag agaggtagag agcacgatga tcttctccag cgtaaaggac gtattttttc
    17341 tgatcttttc tgaaaaggaa gcggtgatcc ggcgattttt tgcttggaat acacctgctt
    17401 tattgaattt agctgcaatc ccaatatcaa ttttactttc tgttgtctgg taggatgcac
    17461 tgatcaaatc gtcaccaaat actcgcagtt ctttttcaac caactgctgt gtaccaaaat
    17521 tggtttgctg tccatcgata cccgttttca catctacttg gcagtcttcg gtcaacggct
    17581 tgatgaccac tttcagggct gcctgatgga gattattttg atcagcaaca cgacaagtaa
    17641 tgacttccac tttttttcct tgagcagttt caatgagcgc atagcgttta agctctccca
    17701 tttctaaatc tagtgcccgc tcgtatgcaa gaactttcat cgtctcaaga gaaaaatgtt
    17761 caccgtcgat ttttatttcc catctgatga catctgggag attcactaac tcggctgatt
    17821 ctgctcctaa aggtcggtta tatacaccag ctgcaaacat tccccttact tgattccgat
    17881 agtcttcctc ctggcttcct ctgataccaa aaaatccatt tccaatggtc atctgactcg
    17941 catacttatt gatatactct aaatcaaact gtttttcttc tactttcata aggtaataac
    18001 ttctcctgtt tctgccgaac gatataaatt ttccaccaga ttctggatga catatccttg
    18061 ccagccatct gcaatcatct gagtctggtc accgagcgcc cgattcacaa aatgagccat
    18121 acttagttca tgtgggtcat taactggcgt ggtcttttgt aaggaaacca gctttccatc
    18181 tacatcttcg aatagttcgc ctggatacag attagcacct gcctgatcgc cacaaaaagc
    18241 cacattcagt ttgtcttctc tgatattcaa agcaaacgaa gtattcagtt ggatgatctt
    18301 gccgttttct aattccagtg tgccaaaaat tgcatcttct actgtgaatt tgcttggatc
    18361 ccatttcccg aatttccctg aatttttttt cgtaccaatt ttttggaagc tgtacgcccg
    18421 aacgcttttt actttaggaa atccagtaat atacatcgct gtatcaagca tgtgaatgcc
    18481 ataatcgatc aaaggcccgc ctccttgaag ttctttgtcg ataaacgttc cccagcctgg
    18541 aacaccagac cgacgaagcg cattcgcttc tacgtaataa atatccccga gaacatcaag
    18601 atgattcttg atcattgttg cttcgtcaga aaaacgatgc tggaatccat aagccaaaat
    18661 ctgcccgttt ttatcggctg tctctgccat ctttcttgct tgatcagctg tcatagctgg
    18721 tggtttctcg cacatcactg aagcattagc ttcgagggca gccaatacat gttcgaagtg
    18781 aaagcgattg gctgtacaga cactcacgat atcgggagaa atctcattca gcatttgtgt
    18841 aactgatgta tacgcatgag aaaatcctgt acgtcggcaa aagtcttctg ctcgctggct
    18901 gactggatca accacagcgg ccaattctaa gacatctgat cttttttgat aataagcagc
    18961 atgtactttt tctgctactt gtccagcgcc tatgattgct actttcttca tttatttctc
    19021 tctcctttgc ttatttactt attgttattc tttctctatt ctttctctaa atcatttaaa
    19081 tgacgcgctg tttccagaca gtttttcaag tattgcaatg attcctgata aattttcact
    19141 tcattttctc ctcgcaaacg acattcatat accatataac cttcatactc attttgaagt
    19201 agcgtttgaa aatggcgagt aaaatcaatt gcgccagatc ctggttggta gcgatgatta
    19261 tctgctaaat ggatatgacc cacatactct ttttgcgtag tcaatgcttt tgaaatatca
    19321 tcttcttcaa tattcatatg ataaaaatca gcgatgatct gcacatgttt caattgatta
    19381 gagtcaatgt aatgacgcgc atccgctaac aaattgatca tatggtcttg gtatcggttc
    19441 aaaggctcca aataaataac cgtacctgtt tcttcggcta ctttatctaa ataacgaagt
    19501 gattcgctga ctgctttata gtctccttct ttgcttcggg gtgaaaccat cggcggtaat
    19561 cgataagtga acattcccca agctgctggg ataacgattc ctttgcctcc aacctcgctt
    19621 agtgcacgca aaatctcagc aatttgacgt acaccattaa gacgccgttc ttcgataaag
    19681 tcaccgatcc acccatcgta gccgttacaa gctgtcacta ctgggatccc tgtttctttg
    19741 attgcctgtt tgactgtgtc gatattttct attaacaact taccgtcgat ttcgtattct
    19801 tcaaatccac agtctttgat aaatctaaat ttttctaaaa tgtctcttgg gaaaaatgct
    19861 tgatcttgcg taccgaattt cattgttctc ctcctcggac ttgaacgccc attttgatac
    19921 tttcttctgg gtgctggtct acataacgca tgtaagcttc tgcgctttct gcaaatggca
    19981 caactggatc aatgatttct tcacaatcca agtaaccgtt catcaataat tcccaacatg
    20041 tgtcctcgat tcgtttacgg ttccatcttg ggtaatctgg gtttggttca ctagatgctc
    20101 gagcaaagac gatttttgca ttattgaaat gtgcttcgcg accaagatta aacccagctg
    20161 gaaaaggttt agcaaaggca acataagaaa tgatcccgcc atagccgatc cctcttaaag
    20221 aagcttgtaa tgcggcagca ctgccactcg tttcaataac tgaatctact ccacgtttat
    20281 ctgtcaattc ctttagacga aaaccgacat ctgctttcat aggatctagc gtgtaatcgg
    20341 caccgtattt ttctgctaat tctctacgct gcgctatggg atcgatccca acgatggtag
    20401 tagcacctgc ttttttagct aattgaatcg caatttgccc gatagcgcct aaaccgaaga
    20461 ttgctacagc atcacctgct cgaacatgtg cttcccggat accacctaaa gcgaattgag
    20521 caggatcgta acatactgca tttttccatt gatccaaccg atcaagttta cgtagtttat
    20581 aattatcaac accgtttgta atcagcgttt cacgaatggg tccataagtg cagactaact
    20641 ctcctttttg atactctgtc accaaactgc ccgtttcttc gatcgtaccg acaatcatat
    20701 ttcctaattg aaattcgcca aataccacac cgcgttggct tccttcttct cttggcaaga
    20761 ataggcgcca ttcttctgaa aattcttcat cgataaatgg acttaatcct ctaaagtcga
    20821 caatttctgt tcctggtttt ggagtagcga aaattactcg gatacgtact tcgttctttt
    20881 cgatctcacg gtcttcgtaa tctttgaatc cggctattct tggttctaat gcaactaatt
    20941 ttttcatctt ttctttcctc tttcttttct ttttatcctt ttacgccgcc ttcgactaaa
    21001 tcacctttaa taaatcgttc agataacgca tacataatga tgactggtaa agcggtcacc
    21061 aatgaagcgg ccatcattcg tccccaaatg tagtctggtg tactgaataa tgtgttcaaa
    21121 ccgattggta aagtaaattt ttcggaggtc gacaggaaaa tcgaagcaaa taaataatca
    21181 ttccacgaaa ccataaagca ataaacgaag acagaaatga ttccagaaat agccaatggt
    21241 ataatgatcc gaataatgat ctggatccgg ctaagaccat cgatcattgc tgcttcttca
    21301 atatcagtcg gaatcgtgtc aaaataactt tttagcatga atatcgcagt aggaagtgtt
    21361 tgaacgacca tcgtgataat cagtgctgta ttggtatcat acaaacctag accggaaatg
    21421 attttaaata atggaacaac gatcaaaata ccggaaaaca tataaacggt gtaaaagcta
    21481 gcattgattt tcgagcgagc tttgaagcgt agttttgaca aagcgtatgc cccgctgatc
    21541 ccaatcacta ctgcagttac ggaggctatc aaggagatca ctaaactatt tttgaaatac
    21601 atgatgaatg gaaaaatctc agcattgaaa atatcctgat aatgttcaaa agtccattct
    21661 ttcggaaaaa tagtttgtgt cgttgcaatt gcttcttgtg aatccttgaa tgatgtcatc
    21721 agcatgatca aaaatggaaa caaattgaca gctaatagca acaaaatcgt cgcgtaaaat
    21781 aagattttcc tgctcttttt atttttcatt tcaagtccac cttctttcgt gagagcaaga
    21841 cgaccgctgc aataatgatg aacaatagaa tcgatatagc tgctgctttt ccaagatcat
    21901 tgaacgcaaa ggctgtctga tacaaataaa cgcctaagat attgacttta ttcgtcagta
    21961 gatagacatc tgtaaacata tagaacatcc agatagatcg taaaacaatc acagttgcta
    22021 gtactggttt gattgccggc agtgtcacga tcttgaactt ctgccaagca tttgcaccgt
    22081 ccatttcagc tgcttcataa agcgttttgt cgactgtttg caaaatagcc aaaaatgaaa
    22141 taaacgcata cggatagtat ctccagatag caaacaaaac gaccataaag aagctagcaa
    22201 ctggctggtc gaaccacagc ggtgcttcgt tgaaaagctg caacctatct actaacagat
    22261 cattgacgat tccataacta ttattgaaca tatatttcca agcaaaaatc aaagaaatag
    22321 atggcgtaac ataacttaat aaaatcagtg aacgcaccgt tttcctaaat ctgaacttgc
    22381 ggttaagcaa aatagctacg gctaatccta aagctgtact gcctgctaca actaagaatg
    22441 tgtaagcaac tgttaaacct aaagaacgat aaaattcact atcacttaaa atttcaagat
    22501 aattgcttaa tccgataaaa acggcgtctg agttaggatt cagcggcata tcgaaaaaac
    22561 tgatctgaat attggaaagc attggaatca gcactaaaac agctaataaa agcatgcttg
    22621 gtgctaaaag tcccatggct aattttaagt cagaatgttt ccttggacga ttcattgaaa
    22681 cctccccctg ataatctgcc aatagctatc tacttttttc gaacaccatt ggcagaactt
    22741 cttgttattt cgtatttttt tgtgcgtcag ctaaagcttg atcgacatct tcgtttccga
    22801 cagttacttg gttcactgct tttccgatca cacctgagct tgtgatatct cccattttcg
    22861 tgaaattctt ttccccgact agtccaaaga cttgtacttc atcaaaagca ctagcaatct
    22921 cagatggcag ctcgccaaaa gacttgatga cttcattttc tttgtaacca tccagttcga
    22981 ctacttgttt attcactggt tgagcaccac caggagacat caagacccac ttttccatgt
    23041 ttttcggttg agataagaaa gctgtgaatg cttcagcagc ctctttttgt ttctcgtcta
    23101 gaccagaaga aatcgtcaat ccagatactg tgccatagac agcttgatct ttttgtgttg
    23161 ggatagcaaa accgatattt tctgagttcc ccgcttcata aacagaaggc aaaatgtaag
    23221 ttgaatagat tgccattggt gctgttccat tcatgaaagc atctttgatt tctgtcacat
    23281 cattagagcc tggcatcgtg tattgggata agttttgata aaacgacaat gcttctctca
    23341 tcttttccgt atcgatcgtt acctcgcctt catcatccaa aacatttgct ccatttgaca
    23401 aagcaaattg agagaacgct tgctcactca ttgttccttc agcagtaggc atagcaattc
    23461 catattgttt attctcttta tctgtgaaat gttgagcaat ttttaaaata tcatcccaat
    23521 tttctggttc tgaaaaacca gcttctgata atttttcttt gtcataccaa ataccttgaa
    23581 cccagccgct aattggtgca gcaatatagc tttttccatc ttctgaacga acaaggtttt
    23641 tggctccgtc ataataatta tcttctccag cttcctcgat aacgttttgg actgccgtct
    23701 gatcaatcag ttcatcttta tccatcactt tagcaaaatc ctgactgact tccattactt
    23761 ctggtaattt accggaacga gctaacgtaa cgatttttgt attgaacgct gattcttcta
    23821 ccggcacttg cttgattttg atgtctggat tttctttttc aaaatcagca accagttcat
    23881 tgatcacact taatcgttcc tgttcgacag aagagtgcat gaattgaatc gttgtctgtt
    23941 gtgattcgtt agagctttga ctttcaccac aagcagtaag aagaaatcca gtagctagca
    24001 gacaggtagt aacaataatt tttttcattt ttttccacct cttattttat tattttcagc
    24061 cacatatatt catacggctg gaatatcaac tttcgttctt gactgcaatg gataatttgt
    24121 ccagaaaaca ggtctaggta atctcctttt ggtaaaagat aacctgctga ttgattggaa
    24181 aaattatgga taactaagac tttctcttcc ttcgcttcgc gaataaaact gataaaagaa
    24241 tctgctgagt ccagtaagta aatcaaacta ttcggatgga aggctttttc tttttttcga
    24301 atagatagca tctgggtcaa ttcaccatat actgctgttc ttaatggatc tgtctgcaac
    24361 tctttctcaa tatctgctaa caaaaatttt tgccgattga tttttcgatt ctctcctgtt
    24421 ttttctacgc ctttgtaatc atttcgactt cccagcacac tttgaatata aattgccggc
    24481 acgcctggta acgttaccaa aaatgaatga gcagctaaaa agcgtttgct tctccattcc
    24541 gtcgtatctg ttggagaact taacgcatct agatacgtag cgtttatctc atatggactg
    24601 gtcgttccat ctgggttttt cttgtagttt actcgggcac cctctttctt cagctgttcc
    24661 actaattcaa ggatcgtttt ttccggcaga atacctcgta ccggattcaa tccgataccg
    24721 tcatgggagg ctaaaaaatt aaaaaaagtt gtttttttcg atgcgaaatc gatggttttt
    24781 aaccattctt tcaacttact tgtattaccc gaacgaatcg cttgaagggt caaaggtggt
    24841 agcgaaaact gatagaccat ctgtgcttca ttctcgccat tcccaaaata actgatatta
    24901 tctttgtgtg gcacatttgt ctcagtgatc aataccgttc ctggagctgc ttcatcagcg
    24961 attgcacgga ataattggat gattttatgc gtttctggca ggtgtataca agaagttcct
    25021 agttctttcc ataaaaatcc cacagcgtcc aagcgaataa atgaagcgcc tttttctaag
    25081 taaaacaaaa gaatatcgat cattttcaat aaaacttctg gatttttaaa attcaagtct
    25141 acttgatctt cgctaaaagt cgtccatacg tgtttttctt tcccgttttt gtcaatgaac
    25201 gttgtaagta acgggctggt ccttggtcta gtcacgctgc ttgtatctgt atccagtggc
    25261 aaatcaataa aaaaatcttt gtacgtatca ttcaagttta aatattcctg aaaccaagta
    25321 ctttcggcag acatatgatt gcagacaaag tcgaacatta accgtgtttc gcttctcatt
    25381 tcttctatat cttcccatgt gcccaaacgg tcgttgattg cctgataatt tacaacggag
    25441 aaaccatcat cagatgtata tgggaaaaat ggcaagaaat gtacaactct aaatgtatct
    25501 gccaaatact tttgataaaa tttcttaaat gtacgcaaag ttggttgctg ctcttcaaaa
    25561 aattgatccc cataagtaat caagaaaata tcttcttcgt cccaatgcag tttgcctgcc
    25621 tggcctttct tctgctgata aacactgact ttttgttcaa tcatagaggc ggttttctca
    25681 gacaaatctg agtcgcgata aatcgcttgt aaaagttttg tatacatcgg attccccttt
    25741 cttttttggg agcgttccca acgatttgat catattatgg aaaacgctta ctgtcaatag
    25801 cattttttta aataattttg atatacacaa aaatacaaat aagaaagctt atgtatcaat
    25861 aattaatagc ttcttaaaaa aatatggtct ctcatgatca tgcaagctat tcctaaattt
    25921 tcaaaatcat agacaaaaaa gaatgtctat tgtactatgg aattattcta aaacgctccc
    25981 aaaaaggagg tgcatataaa attgaaacct actatttatg acattgcgaa aaaagctaat
    26041 gtctcaaaat caactgtctc cagagtatta aataaccagc caaatatctc tgataaagca
    26101 aaagcaagtg tacttcaagc aatcaaagaa ttgaattatg aaccgagcaa aattgcaaga
    26161 ggactgtcag gaaatggttt tgacgcgatt ctagcattat ctcatcgtac ttctcatacg
    26221 acctatggca atcctttttt ttcagatgtt attcaatcca tttctgccgt ttctgaacaa
    26281 aataacttcg acttgattct acaaacggca aaaacaccag aagaagagct agaaaaatgc
    26341 gcgaaaaaga tccaagaaaa aatgatccga ggaattatta ttttaagctc tacgatggat
    26401 gaaacacttc tttttgaatt ggatcaatac aatattccta ttgtggtaat cggaaaagtc
    26461 ggaaacgact acacgaacat ctactcagtg gacacggata atttccagga tagttacgat
    26521 ttggtggaaa cactgatcaa gaatggacac cgtcatatcg gctgtctcca tgctccgaca
    26581 gaagtttatg tatccaatga tcgtctcaat ggttaccgtc aatgcttatt tgatcaccac
    26641 ctagatatcc gtaatgaatg gattatagac ggcggctttc gcttagaaga tagcatggca
    26701 gcaatgaatg atttaatgaa gctacgagaa agaccaactg cgattttttc taccgatgca
    26761 ttaaaatcat tgagtattta caaagtggca gaacaatctg gaaagcagat acctgatgat
    26821 ctttcgatcg caggattcag tgatccctta ttgtcctccc tattttcgcc acagttgact
    26881 cggatagaca ttccgacaaa tcagttagga atcaaagcca cagaactttt attccaacta
    26941 atccaccacc aataccctga agaaaaaaga atcattcttt caaccgagat tactctcaca
    27001 gattcgatcc aacaacaaga aatgtagaac agaattataa aagaacagaa acactgagga
    27061 taagtcagtt actctgttct tttttcaatc actcatccct cgttaccccc tcccggtatt
    27121 ttagcgaatt tttcttattt tccatctgtt ttagatagct gtggataact ataatgtttg
    27181 tgttaaacta ttttttccac agggaagaaa aaactatttt taaccacgtt gtgtataagt
    27241 ttttatagtt cgttttttta aacacattta cccttatttc aatccatgtt atttggggat
    27301 acttatctct aaaacataaa tagaataaca gacatgtcta ctggttttgt tttattcgag
    27361 gaattattca ataatagcta gcaaaatatt aaaaataacc gctctatctt cccatcaatt
    27421 tattttgcat tcaaaaaatg atctatcttt acttttgttg attgacttct cttggaagat
    27481 gatcgttccg ataccttaat tggatacgaa ccgatgttgt taagatcctt tcccactttt
    27541 cttctagtta gacaaattat tttagacaaa ccaaaaaaga ggttgtgaca ataatttgtc
    27601 acaacctctt ttttaaaata tctattttgt ttgattgttc attgcgtctt ctgcagccat
    27661 ttgcgcttca atatctgaaa tactgtagac attttcgctt gctacaccga cttcttttgg
    27721 ttccatgtca cgataacgtt gcataccagt accagctggg atgatcttac ctataataac
    27781 attttctttc aaaccaagaa gaggatcttt cttaccgcgg atcgcagcat ccgtcaagac
    27841 acgagttgtt tcttggaatg atgcagcaga taagaaacta tttgtttcta atgatgcttt
    27901 tgtgatacct agtaagacag gtcgagaagt tgcaggaacg cctcctgaga ctagcgtatt
    27961 gtagttttga tctttaaagt ctgcgatgtc taataatgta cctggtaaga tatctgtatc
    28021 acctggatcc attacacgaa ctttacgcag catttgacga accattactt cgatatgctt
    28081 gtcgccgatt tctacccctt gcatacggta aacacgttgt acttcacgaa gcaagtagtt
    28141 ttcaacagat aatacatcgc gaacttgcaa caattgtttt ggatcgattg atccttctgt
    28201 caatggtgca ccacggtgga tcatatcgcc ttctgctact ttcatacgtg ctgtataagg
    28261 aacagtatac gtacgtgtat ctgtttttcc tttgattgtt acttctttgg tacgtgttgc
    28321 aggatcttct gagatatcga tgacatcccc tgttacttct gtgatcactg cttgcccttt
    28381 cggattacgt gcttcaaaga tttcttggac acgaggaaga ccttgagtga tatcgtctcc
    28441 ggcaacccca cctgtatgga atgtacgcat cgtcaactga gtaccaggtt caccgattga
    28501 ttgagcggcg atcgtaccaa ctgcttctcc gacttcaacg tcagagccag ttgcaaggtt
    28561 gcgtccgtaa caatgtttgc agacaccatg ttttgtatta catgtgaaga cagaacggat
    28621 tgtcactgtt tcgacacctg catcaacgat ttgttttgcg atgtcttcgg aaatcaattg
    28681 gtttcctgca atgatcaatt catttgtttc aggatgacgt acttctttac gggtgtaacg
    28741 tcccactaaa cgatcttcta atgattcgat gatttcattt ccctcgcgga tggcttggat
    28801 ttcaagacct cggtcagtac cgcaatcttc ttcacggatg attacatctt gggccacgtc
    28861 aaccagacga cgagtcaagt aacctgaatc ggcagtcttc aaggctgtat cggtcatccc
    28921 tttacgagcc ccgtgagttg agataaacat ttccaagacg gatagtcctt cacggaagtt
    28981 cgaaatgatt ggcaattcca tgattcgacc attaggagcg gccatcaaac cacgcattcc
    29041 ggcaagctgt gtaaagttgg aaatgttacc acgagctcca gaatcagaca tcatgaagat
    29101 tggatttttc gcttccaaac cttccatcag tttttgttgg atgctgtctt ttgcagcatt
    29161 ccaaacagca atgacacgtt cataacgttc gtcatctgtg atcagaccac gacggaattg
    29221 ttttgtaata gtttcaactt gtttatgggc attttcaatg atttcttgtt tttcattcag
    29281 tacactgatg tcagcgatcc ctactgtgat accggcatgt gtcgaatgtt tgtaccctaa
    29341 gtctttcata cggtcaagca tcttagaagt ttcttttact ttgaatcgtt tgaagacttc
    29401 tgcgatgatg tttcctaagt ttttcttctt gaacggtaat actaattctt gctctttgat
    29461 atgtgcagga atatcagtac cagcttcaac aaagtatttg tccggtgttt ggacggtcaa
    29521 gttgaagtct gttggttcat tcagataagg gaattcagga ggcatgatct cgttgaagat
    29581 gatcttacca actgttgtga tcatcgtacg ttctttttgc cattcagtaa atggtttttc
    29641 acctaatgag ttagggttca caccgatacg tgaatgtaaa tgaacatatc cgttgcgcca
    29701 tgcgataacg gcttcgtttt gatctctgaa gaccattcct tcgccttcgc gtccttcttc
    29761 ttccattgtc aagtagtagt tacctagaac catatcttga gaaggagtaa caactggttt
    29821 accatcttta gggttcaaga tgttttgagc agctaacatc aacatacgtg cttctgcttg
    29881 tgcttcttca ttcaatggaa cgtggacagc catttggtct ccatcgaaat cggcattata
    29941 agcttcacat acaagtggat gcaaacggat tgcgcgtcct tgtactaaaa ctggttcgaa
    30001 tgcttggata ccaagtcggt gaagcgtagg tgcccggttc agcaatactg ggtgttcctt
    30061 gattacgtct tctaaaacat cccatacttc gtcttcttga cgttcgattt tacgtttcgc
    30121 atttttgatg tttgaagcta gttcgcgttg aacaagctca cgcatcacga atggtttgaa
    30181 taattcaatg gccatttctt ttggaagtcc acattggtac atcttcaaga aaggtccaac
    30241 aacgataacg gaacgacctg agtagtcgac acgtttacct agcaagtttt gacggaaacg
    30301 accttgtttc cctttcaaca tatgagaaag agatttcaat gggcggttac ctggtccagt
    30361 aactggacgt ccgcgacgac cgttatcgat caatgcatct actgcttctt gcagcatacg
    30421 tttttcattt tgaacgatga ttccaggtgc attcaagtct aacaaacgtt tcaaacggtt
    30481 attacggttg attacacgac ggtaaagatc attcaagtca cttgttgcaa aacgtccacc
    30541 ttctaattga accattgggc gtaaatctgg tggaataaca gggataacgt ccataaccat
    30601 ccagcttggt tgatttcctg aagcgcggaa tgcttctaaa atatccaaac ggcggattgc
    30661 acgtgtacgt ttttgtcctt gtgcagattt caattcttct ttcaattcgg ctgcttctgc
    30721 atctagatca acattatcaa gtaattgttt aatcgcttct gcacccatag cagcttggaa
    30781 ttcttgtcca tattgttcac gtttttcgcg atattcgcgt tctgtcaaca attgtttttt
    30841 ctctaaattc gtatttcctg gttcgatgac tacatatgaa gcaaaataaa tgatttcttc
    30901 caaagcgcgt gggctcatgt ctaatacaag acccatacgt gaaggaatcc ctttaaagta
    30961 ccagatatgt gaaacaggag ctgctaattc aatatgtccc atgcgttcac ggcgaacttt
    31021 cgaacgagta acttccactc cgcatcgatc acaaacgatt cctttataac ggatacgttt
    31081 gtattttccg caggcacatt cccagtcttt tgtaggacca aaaatccgct cacagaacaa
    31141 cccttcgcgt tcaggtttta aggtacgata gttaatcgtc tcaggttttt ttacttcacc
    31201 gtaagaccag cttctgattt tttcgggaga agccaaacct atttgcatac tttcgaattt
    31261 atttacatcg atcaaaaggg gttccctcca tttcatttaa tggcaaaccg caagacggct
    31321 gatcttcgac cgccttgcag ctcatagacc ggattagtct aaattatctt ctgcggtttc
    31381 aaagttttgg atgacatcgt ctttttcatc ttccacttgt tcagcagctt tcttttctaa
    31441 ttctttggca gtttgctgtt cggcaaattt tgtcaaagca tcaacagtga tcaaatcgtc
    31501 gtcttcatcg tccatgtcgc gaagttcgat ctctgtttct tcgatatcca agacacgcat
    31561 gtccagacct agtgattgca attctttcac caatacgcgg aatgattccg gtacacctgg
    31621 ttttggaatt ggttcaccct tgacgattgc ttcgtatgtt ttcacacgtc cgactacgtc
    31681 atctgatttg tatgtcaaga tttcttgtaa agtataagcc gcaccgtaag cttccagtgc
    31741 ccatacttcc atttcaccaa aacgttgtcc accaaattga gctttacctc ccaatggttg
    31801 ttgtgtaacc aatgagtaag gtccgattga acgtgcatgc aatttgtcat cgaccatgtg
    31861 agcaagtttg atcatgtaca tcacaccgac agacacacgt ccatcaaatg gttcacctgt
    31921 acgtccgtcg tacagaacag ttttcgcatc gctggccata ccggcttcac gaactgtttc
    31981 ccatacgtct tcatcacttg caccatcaaa tactggcgtt gctacgtgga tacctaactg
    32041 acgtgcagcc atacccaagt gtaattccaa tacttgcccg atgttcatac gtgaaggcac
    32101 ccctaaagga ttcagcatga tatcgattgg tgttccatca ggtaggaatg gcatatcttc
    32161 ttccggcata atacgggata caaccccttt atttccgtga cgaccggcca ttttatcccc
    32221 ttcatggatt ttacgttttt gaacgatata aacacgaact aacatgttta cgcctggtga
    32281 caattcatct ccagcttcac gagtaaagat tttcacatcg tgaacgatac cgccgccgcc
    32341 atgtggtaca cgtaatgatg tatcgcggac ttcacgagct ttttcgccaa agatcgcatg
    32401 caatagacgt tcttctgcag ataattctgt tacccctttt ggcgtgactt tccctacaag
    32461 caaatcgcca tcttggactt ctgcaccaat acggatgata cccatttcgt ctaaatcttt
    32521 taatgcgtct tccccgacat tagggatttc gcgtgtgatt tcttcaggtc ctaattttgt
    32581 atcgcgggct tctgattcat attcttcaat atggatagaa gtgtatacgt catcttttac
    32641 caaacgacgg ctcatgatga tcgcatcttc atagttgtac ccttcccaag tcatgaaacc
    32701 aactaaaacg ttttggccta gagccatttc gccttgttcc atagatggtc cgtctgccag
    32761 agtatcccct ttttcgactt tctcacccaa atgaacgatt ggacgttggt tgtagcttgt
    32821 tccggagttt gaacgacgga attttgttac atcgtattta tctaatgcac cgttgtcgcg
    32881 gcgtacgcgg atttcagaag catcaacgta ttcaacgaca ccatcatgtt tacataacaa
    32941 agcagctcct gagtcatgcg ctgatttgta ttccatacca gtaccaaccc atggtgcttg
    33001 aggattgatc aacggcactg cttgacgctg catgttggca cccatcaagg cacggttgga
    33061 gtcatcgttt tccaagaaag gaatacatgc tgtcgcaacg gcaactactt gtttaggtga
    33121 tacgtccatg tagtctactt tatcaataga tacttctaag ttttcacttt gagcacgagc
    33181 cataacaacg tcttgagcaa atgttccatc ttcattcaat gggctgtttg cttgggctac
    33241 gatgtaatgg tcttcgatat cagctgtcaa gtagtcgatt tggtcagtaa cacgacctgt
    33301 ttcacggtct acacgacgat aaggtgtttc gataaatccg aatttattta ctttcgcata
    33361 actggacaaa ctattgatca acccgatgtt tgggccttca ggagtttcga tcggacacat
    33421 acggccatag tgggagtagt gaacgtcacg aacttcataa ccggcgcggt cacgagtcaa
    33481 tccgccaggt cctaaggcga aaagacgacg tttgtgtgtc aattcgccaa gagggtttgt
    33541 ttgatccatg aactgtgaca actgagaaga accaaagaat tctttgatac ttgccacaac
    33601 tggacggata ttgatcaatt gttgaggtgt caatgtttca gtatcttgga tcgacattct
    33661 ttcacgaacc acacgttcca tacgtgctag cccgatacgg aattggtttt gtaaaagttc
    33721 accgactgaa cggatacgac gatttcctaa gtggtcgata tcatcgacat tgccgatacc
    33781 ttccatcaag ttcaagaaat agctcattga agcaatgatg tcggctggac gaaccgtttt
    33841 tacagctgct tctggatagc cgtttccgat cacgtttact tcacgttcag ggtctcttgg
    33901 tgaaaatact ttgatgactt ggacagtcat tggatctgtg accacaccgt cttctgatgg
    33961 atagtaagtc actgaattta ggccattatc aatgaaagga gctagtgttt ccatgacttg
    34021 gtgagtcaga actgttcctt tttcaacgat gatctcgcct gtttctggat caactaatgt
    34081 ttcagctaat gtcagattca atagacgtgt tttcaaatct aattttttgt ttactttgta
    34141 acgaccaacg tttgctaagt cgtaacgttt tggatcgaag aaacgagcat tcagcaagtt
    34201 acgtgagctg tctgctgttt ttggttcgcc tggacgcaaa cgttcgtaaa cgtctttcaa
    34261 accttcttct gttcttgagt cgcttgcgtt tttatgcaag tctttttcga ctgtattgcg
    34321 taatgtttcg ctgtcgccga agatttcaaa gatcgtatca tcggaaccaa atcctaacgc
    34381 acgaactaat acggttaaag gaatcttacg tgtacggtcg atacgtacat aagagatgtc
    34441 ttttgcatca gtttccattt ctagccaagc tccacggtta gggataacag tagaaccgaa
    34501 tccttctttt ccgtttttgt cgacttttcc atggaaatag acacctggtg aacggactaa
    34561 ctgagaaacg attactcgct ctgccccgtt gatgatgaat gttccttgtt ctgtcattaa
    34621 tgggaaatca ccgaagaata cttcttgtgc tttgatttcg ccagtctcgc ggtttgtcaa
    34681 acgcaatgtt acatgtaatg gtgcagagta gtttgcatca tgcgcacgag cttctgctac
    34741 tgtatacttt ggttctttca attcataatc tacaaattcc aaagatagat tgccattgaa
    34801 gtcatcgatt ggcaaaatgt cttcaaacat ttctctaagt ccctcatcta agaaccattg
    34861 gtaagagtct gtttgaattt cgatcaaatt tggtaattcc aacacttcac tgattcttgc
    34921 gaaacttcta cgttcgcgat gttttccgta ttttactacg tgtccagcca agctcttcac
    34981 ccctctaaaa tgtcattcaa aaagactacc cgatcaattg ttacaataat atttcaaata
    35041 ttatttttag gtaacaacag acattttttg cggcttttag gcaaaaaaaa accaaaaata
    35101 gaacattctc ttgaaacctt acttcgtgag cttctacttt tgtttcctta tattaaagcc
    35161 gaaacggaca atatttcgtt tctgcctttt cttcatcaga tagtttttgc aacttcatat
    35221 actacactta ttttctataa aagtcaacac ttcctggcgt ttcttctgct ttttcgcaac
    35281 attttcttaa tgttttcaat tttatgtttt caattatctg acaattctta attgacagac
    35341 ctttttatct cggttatact ttagaaaatt cattttgtgg aggaacttct atgcgaacca
    35401 acatcaacca aatcgcacca acacaactga ataactttta ctttagctac tttagatagg
    35461 tttgtattca tcatgatgga tacaaacgtt aaacgacagt ttgtatctat gatggctaaa
    35521 gaactttgta ttgcagcaaa aagccacgta gacaaaatgc taagtggctg agcagtgaaa
    35581 atacaaagta aaagtatcaa gcattctact ttttcaattt attttccgac ttttcaatcc
    35641 atttggacat tttgtctgaa tggatttttt gtttcccaaa attaaggagg aaaaagaaat
    35701 gaaaaaaaat ataatcatcg gattaggcgc tgccctgcta ctagctttag gaggttgcgc
    35761 acaaaaagac aattccgcag aggcatcaga tggacaaaaa acaattggcg tattgcaact
    35821 tgtacaacat aactcgttag atgctgccta taaaggattc aaagaaggat tagcagaaga
    35881 agggtataaa gaaggcgata atctaacaat cgattatcaa aatgcccaaa acaatcaaga
    35941 caacctgaaa agtatgagtg agaaactcgt caaagaagat cctgatttgc tacttggaat
    36001 cgccactcca gcagcacaat ctttattaaa tgaaacaacc actatcccga tgactgtcac
    36061 agcggtcaca gacttggaac aagcccattt agtcacatcc aatgaaaaac ctggcggcaa
    36121 tgtgactggc acgacagata tggtgccaat cgaaaaacaa atcggcttac tgttaaatat
    36181 cgtgccagac gccaaaacaa tcggcatcat gtataacaac ggtgaagcaa actctaagat
    36241 ccaagctgat ttggcagaaa aagaattgaa aaaagcgggc gtcaaagtca aagtactgac
    36301 agcaaattcc acaaatgatg tccaacaagt gacgaaaagt ctagctaaag atgtagatgg
    36361 aatctatatt cctactgata acacgttcgc aagtgcggca agtgttgtcg gtgaagtcgc
    36421 aaaagaaaca aaaacacctg tcgttgctgg cgcagttgat caagtcaaag acggcggtct
    36481 agcaacagta ggaatcgact acgaaagctt gggcaaacaa acagggatca tggcagcaaa
    36541 aatcttagac ggcaagaatc caagtgaact tcctgtcgaa acagcgaatg atttggaact
    36601 gtatgtcaat aaagacatgg ccaaagcatt aggcatcaat ccagacagca tcaaagaagc
    36661 tgaataaaac acaggaggat tctcatgaca aatttgctct ctcttttctt atcatctgca
    36721 tcgcaagggg tcttatgggc cctacttgcg attggtgtat acgtcacttt ccgtatcttg
    36781 gacattgccg acttgactgc tgaaggaagc tttcctttag gtgcagggat cgcggcagta
    36841 agtattacaa atggctatca tccattgaca gcttgtcttc taggcttttt agggagtgcg
    36901 gcagcagggc ttgtttccgg actgcttcac acaaaattga aaattcccgc ccttcttgca
    36961 gggatcatca ccatgactgg tttatattct gtcacatccc gtgtgatggg tgcgccgaac
    37021 atctctttat tgggtcagcc aacgatcttt cattgggtcg agtcattcgg cataacaaaa
    37081 gacaacgctg tactgatcgt cggtctgctt tttgctttga tcgttgtatg tttacttgtt
    37141 ttgttcttac gtacagaaac aggacttgct attcgtgcaa ctggcgataa tctggcaatg
    37201 agcgaagcaa acgggatcaa cacagataat atgaagatca tcggttatat gatttctaat
    37261 ggatgcattg ctctttctgg ctccttgctt gcgcaaaaca acggctttgc tgatttaaat
    37321 tctggtattg gaacgatcgt aattggactt gcttctatta tcatcgcaga agttttgtta
    37381 cgtaaccagc cactatttct ccgtctcttg actgtcgttt taggtgcggt catttatcgt
    37441 tttattttag cgttagtctt cgaactgaat gttgaaccaa gtgattcgaa acttgcttct
    37501 gctttcgtgc tagtgatctg tctttctttc ccgcagatcc agcaaaaatt ccatttacct
    37561 caaaaaaaga aaggcggtag tgtcaaatga atgacgtctt aacattggaa aatctccatc
    37621 atacctttga aaaaggaacg atcaacgaaa atcatgtcct gaaaggcatt aatctttcct
    37681 tagatcccgg cgacttcgtg acgatcatcg gtggaaatgg ggctggtaaa tctactttgc
    37741 tgaacagcat cgccggtaca ttttctgtcg atcagggtca aattttattg aatggaaaaa
    37801 atatcacgaa aaaatctgtt gtcgaacgtt cgaaatccat cagtcgcgta ttccaagatc
    37861 ctaaactagg gacagccgtt cgtttaacgg tagaagaaaa tcttgctctt gctatgaaac
    37921 gaggaaaaaa acgcggcttc ttccgtggtg tcaaaccaca agaccgaaca tttttcaaag
    37981 accagctggt tcggctaaat ttggggttgg aaaatcgttt atcctcagaa atcggtttgc
    38041 tgtctggagg acaacgtcaa gctattacgt tattgatggc cacattacag cgtccagaac
    38101 tgatcttatt agatgaacac actgcagcgc ttgaccctgc tacttccaaa acggtgatgg
    38161 aattgacaga aaagctgatc actgagcaga atctcactgc ttttatggtc actcatgaca
    38221 tggaagacgc gatccgctat gggagtcgac tgatcatgct gcatcaagga aggatcgtcg
    38281 tagatatcca gcaagaggaa aaacagcagc tcacagtgcc ccaattatta gcgttgttca
    38341 aacaaaacag cggcacggca ttaaaagacg atcaagtact tttatcttca taatcagaaa
    38401 gaggatggga caaaaaatga acgcccaccc tcttcttttt tctctttcct tctttcgttt
    38461 ttgctttatg tatcaaccgt tgtttcttcg aaaactattt tgttctctcc ttcttcctga
    38521 tagaatggat gggaaaggag cttgatgcca tgacaacgaa agacaaggta cttcaattat
    38581 tgaaaaagac accagatttt ctttccggag aaaagttggc acagcaactg gaagtttccc
    38641 ggacaagtat ttggaaagcc atcaaagaat tggaaaaggc aggctatcgt tttgagcacg
    38701 ggcctacagg gtatcgttac ctgccctctg acgtactaga tgcaaaagaa atccagcaag
    38761 agctacggtc gtttattcct gatttgaaag tacaaacgat gatgacttct gaatctacga
    38821 tgaaagatgc caaactggca gcagctcaag gagattctgt ttcgaagtta tttgttgctg
    38881 atacacaaga acaagctcgt ggacgttttg gacggccttt tttcgctgaa cctggacgag
    38941 gaatctacat gagtctcttg ctccatccag acaaacggtt tgatgaattg cctcaatata
    39001 cgatcatcgc agccagtgcc tgtgtgaaag ccattgaatc tgtaaccggt cgttctgctt
    39061 cgatcaaatg ggtcaatgat atctacatgg atggaaaaaa agtctgtggg attttatctg
    39121 aagcagtcag tgatatggaa agcggcagga tcagtcatat catcattggg atcgggctta
    39181 atttttctgt tcctcaaaat cattttccag ctgatctcca agaaaaagcc atctctgtct
    39241 ttcccgacgg acaagctagt gtcacaagga atcagctaat cagcaaaatc tggcaagaat
    39301 tgttcactta tctttctcac ccagaaaaag cgttggactt ctataaagaa aaatcattcg
    39361 tattgggaaa aaccgtgtcg ttcaatcaaa aaggaacgac ttatgtcggt cttgcaaaag
    39421 aaatcggtga tcatggcgaa ctgatcgtcc aaacaaatga acagaagatg agtttgtctt
    39481 ctggcgaaat cagtctcaca tctatccgta cgcaataatt atcagatttc acaaaaggac
    39541 acctgatctc atacagtgtc cttttttctg aattctcttc aaaagactct ccttattcta
    39601 tcagctgaca gtttctctat cctctagaaa aaggtattct aaaaatatct ataaagcatg
    39661 gtacactttc tttaaatgaa tcaatgcaaa aaacaagaga gtcatcagtt tacacgatca
    39721 aaagagatag caggccgctt cctttttcaa tcttatagat agaccatggg taacgataaa
    39781 aacaaaaaag aacttgcgac ttattttgcc gtaagttctt ttttagctag tgccttaatc
    39841 tcttaatccc aacaaacgtc tcgcatagat cacctgacca gagtgcatag cagcatcatc
    39901 aataatagaa acgagacgca ttcctcgtgt gactggtggt gtccagttct cgtcaattac
    39961 ttcatctagc tcggaaggtt ccagccttct taagtaagaa atagcaaaat cagcagctcc
    40021 tcgcaagtat cctagcagat cttctatttg attagcttgg atctgctttg cttgttccag
    40081 actatgcttc caatcttgtt cgttatctgc tatcgtcatc ggaaaccggc tttcccagtc
    40141 ttgactatgc caaattggag aagttcctgc taaatcagca atctggaaat ctaattctcg
    40201 agcggtatgc caagccagcc aagtcattga tttgatctgc ggggctctat cttccactgg
    40261 aaaacgattg gcctcctcaa tagagacgcc ttcaaacaaa cgttcaaacc gatcgtatgc
    40321 ccgatccaca ctctcgcata gcatatctaa ataatccatt tattttcctc ctttttattt
    40381 atcctactta ctttttccta attctaggat acctacttat atgttactac acacccttat
    40441 tttttacact ttaacagtca ccatcatcaa tagtttggag attgaaagaa aaagatagtg
    40501 tcgaactatc aattgaacaa gaagcaacaa tatgaacgtt tcattaatat tctttaaata
    40561 aacaatgatt tttcaaacga acagtttaag actaggagaa aaagagtata ataggaaaat
    40621 gtttgaaagg aaaggaaggg gaaaaatgaa aaaaagggca agtttactag tcctagttgc
    40681 tttgttgttc aatatctttt cgtatggtgt ggccgtttca gcggaaacat acattcctaa
    40741 agaccctggg aatatttata atgatctaac tggtaactat ggcttgttag gaattgctag
    40801 tcaattccac gtatttgcta aaaataagac aactgtgaat gcacatacag acggaaatat
    40861 agcaacacat gaacttgatg caaaaaataa ttttggtaca gagcttcatg aaggtttatt
    40921 gaaccaagaa ataaattata tacaaaaaac tgattctttc gctaattctt caggcatacc
    40981 tacaggtagc acaagaatga ataaatttgt cgttggcagt aacgtggatg tagcacttca
    41041 agatggtcat cctacagtca atggatccag gcttgatcac ttaactccag atgattttta
    41101 taaagatcgt gctgggcatg aatatattga tttcgagcag gaatttgcta aattgaatgt
    41161 agcagcaaat gatcttgcaa cgatcactcc agctaaaaca tatactgctg cagattttcc
    41221 agacatgaac aatcggacaa tcgatttaac tgatttatca gataccgggt ttttattggt
    41281 aaatatcgat gcagaagtgt taacgatgaa tacgccactt caaatcatta atccaaatga
    41341 tcaagtagtt gtatttaatg tcatcaacag ttcttctgca ttgaacgtac agtcaccaat
    41401 caaatacaat gatcgttcaa atcatgaaac agaagatttt tcggatgcga atatctcttg
    41461 gaattttgga aatgagatga ctgatttgac aatcagtgct ccttttcaag gaacaatcct
    41521 tgcgcctaat gctactatcc gcattactca aaaccaagac ggaacgatta taggaacaaa
    41581 tgtgatttta gatgcagcta ccaatcgttg ggatcctaac gaaatattta tcagcgacaa
    41641 tggtacagat acgacagaca caagcgacag tacagataca tctaccacaa gtgatagctc
    41701 agattcatca acttcaagcg acagtacaga tactacctct accacaagtg atagcacgga
    41761 tacatcagct tcaagcgaca gtacagatac tacctctacc acaagtgata gcacggaca
//
LOCUS       DAYYEF010000020        41523 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000020 DAYYEF010000000
VERSION     DAYYEF010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41523
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.020"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            214..498
                     /locus_tag="ACHA1B_001237"
     CDS             214..498
                     /locus_tag="ACHA1B_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HFM8702013.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(815..1198)
                     /locus_tag="ACHA1B_001238"
     CDS             complement(815..1198)
                     /locus_tag="ACHA1B_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HFM8702014.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(1200..1784)
                     /locus_tag="ACHA1B_001239"
     CDS             complement(1200..1784)
                     /locus_tag="ACHA1B_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HFM8702015.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="ACHA1B_001240"
     CDS             complement(1831..3306)
                     /locus_tag="ACHA1B_001240"
                     /EC_number="4.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HFM8702016.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="ACHA1B_001241"
     CDS             3487..3798
                     /locus_tag="ACHA1B_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702017.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="ACHA1B_001242"
     CDS             complement(3913..6249)
                     /locus_tag="ACHA1B_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HFM8702018.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="ACHA1B_001243"
     CDS             6391..7059
                     /locus_tag="ACHA1B_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM8702019.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="ACHA1B_001244"
     CDS             7062..8105
                     /locus_tag="ACHA1B_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM8702020.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="ACHA1B_001245"
     CDS             complement(8342..9223)
                     /locus_tag="ACHA1B_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFM8702021.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="ACHA1B_001246"
     CDS             9382..10110
                     /locus_tag="ACHA1B_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HFM8702022.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="ACHA1B_001247"
     CDS             10266..10583
                     /locus_tag="ACHA1B_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFM8702023.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="ACHA1B_001248"
     CDS             10576..11184
                     /locus_tag="ACHA1B_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HFM8702024.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="ACHA1B_001249"
     CDS             11239..12030
                     /locus_tag="ACHA1B_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="HFM8702025.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12656
                     /locus_tag="ACHA1B_001250"
     CDS             12168..12656
                     /locus_tag="ACHA1B_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HFM8702026.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="ACHA1B_001251"
     CDS             12707..13579
                     /locus_tag="ACHA1B_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HFM8702027.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="ACHA1B_001252"
     CDS             13755..14117
                     /locus_tag="ACHA1B_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFM8702028.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="ACHA1B_001253"
     CDS             14126..14878
                     /locus_tag="ACHA1B_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702029.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="ACHA1B_001254"
     CDS             14892..16694
                     /locus_tag="ACHA1B_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702030.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="ACHA1B_001255"
     CDS             16971..18011
                     /locus_tag="ACHA1B_001255"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFM8702031.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="ACHA1B_001256"
     CDS             complement(18063..20207)
                     /locus_tag="ACHA1B_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFM8702032.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="ACHA1B_001257"
     CDS             complement(20564..21937)
                     /locus_tag="ACHA1B_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFM8702033.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="ACHA1B_001258"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="ACHA1B_001258"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016872 - intramolecular lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HFM8702034.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="ACHA1B_001259"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="ACHA1B_001259"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004747 - ribokinase activity [Evidence
                     IEA];
                     GO_process: GO:0006014 - D-ribose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HFM8702035.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="ACHA1B_001260"
     CDS             complement(23385..24398)
                     /locus_tag="ACHA1B_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HFM8702036.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="ACHA1B_001261"
     CDS             complement(24479..25078)
                     /locus_tag="ACHA1B_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HFM8702037.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="ACHA1B_001262"
     CDS             25264..25965
                     /locus_tag="ACHA1B_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702038.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="ACHA1B_001263"
     CDS             25975..28686
                     /locus_tag="ACHA1B_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HFM8702039.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="ACHA1B_001264"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="ACHA1B_001264"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008788 - alpha,alpha-phosphotrehalase
                     activity [Evidence IEA];
                     GO_process: GO:0005991 - trehalose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HFM8702040.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="ACHA1B_001265"
     CDS             complement(30825..32006)
                     /locus_tag="ACHA1B_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFM8702041.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="ACHA1B_001266"
     CDS             32258..33781
                     /locus_tag="ACHA1B_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFM8702042.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34578)
                     /locus_tag="ACHA1B_001267"
     CDS             complement(33850..34578)
                     /locus_tag="ACHA1B_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFM8702043.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34591..35872)
                     /locus_tag="ACHA1B_001268"
                     /pseudo
     CDS             complement(34591..35872)
                     /locus_tag="ACHA1B_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
     gene            complement(36013..36615)
                     /locus_tag="ACHA1B_001269"
     CDS             complement(36013..36615)
                     /locus_tag="ACHA1B_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFM8702044.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36860..37066
                     /locus_tag="ACHA1B_001270"
     CDS             36860..37066
                     /locus_tag="ACHA1B_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702045.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37378..38097
                     /locus_tag="ACHA1B_001271"
     CDS             37378..38097
                     /locus_tag="ACHA1B_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFM8702046.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38178..38861)
                     /locus_tag="ACHA1B_001272"
     CDS             complement(38178..38861)
                     /locus_tag="ACHA1B_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family protein"
                     /protein_id="HFM8702047.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39081..41267
                     /locus_tag="ACHA1B_001273"
     CDS             39081..41267
                     /locus_tag="ACHA1B_001273"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HFM8702048.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGKKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        13484 a         7352 c         8323 g        12364 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttattt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataac ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    33961 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    34021 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag
    34081 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    34141 tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag
    34201 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    34261 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    34321 ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    34381 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    34441 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    34501 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    34561 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    34621 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    34681 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    34741 ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac
    34801 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    34861 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    34921 atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat
    34981 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    35041 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata
    35101 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    35161 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt tttttctaga tctttgatat
    35221 aatcctgttg catcctgact tgttgctcta ataactgatc agctaatttc ttattagaga
    35281 ttttccaata ataaaccaag atgatcaggc caacacacag atatagaatg aaaaaactcg
    35341 tattcaaagc taagacatca ggtgtttcac cagaaaaacg ggtataaaaa ataatgatat
    35401 agtatgtaaa taatatcaat gtcccgatcg taccgatcat acggcggtcc acagtgtgaa
    35461 accaagtctc taacgatttt tttaaacaaa aagctaataa agcagataaa aaagcggata
    35521 agacaatgtg aaaatactgc aatgaatctc ctggttcaat aaccgaagat ttcaaaacaa
    35581 aaaaatcgcc gatgcttgtt aagtgatctc ctaaaagcga cgtcaataac ccaaaaggaa
    35641 gcgcgtaaac caattgttga cgcgaagtcg aaaagaagaa aaaagtaagc atcagcattc
    35701 ctatagcaat tagagcagta aaaatcccta aaatcgaata gacccatcca atcaaaatac
    35761 aagaaatcag aatgactccc gcaaacagat atttgtatcg gatgtgatgg tcaatcaata
    35821 agatacaaat tgtgtaaatc aaatattgca acgctatgga ccataaaaac ataaagtaca
    35881 gctcccattg atttttacca aattatagca caattggcgt attatttttt taatttttca
    35941 gggattttga attcagaact cataccaaag cagcagccag atacaaaaaa gtcagataag
    36001 ttagttaatt gtttaatgat tgtttttttc atgaaagatt cctccaaaat tcatcaagta
    36061 gtttgtaata ggaagcaacg tagctatttc taaaacaatc ccaagtagca aataggtaga
    36121 aaagtaagaa gctgagaaaa ataacgtaat gagagaaaaa attagaaaca tgctgatcgc
    36181 cttctttaat aatgggggac gtttctcggg ttcaatggga ttgattgctg tacctcttga
    36241 tccatagcga agcagtaaca aaaagcagct gattaacaaa aagaccatca ttgggaagga
    36301 gatagtcaat tgcagatgtt tcatcaccaa gggaacgccc cataaataaa gtagtgtcca
    36361 cagcagacaa acgaattcag agtcggaatg caatccataa gcatatctgc ggatgcagat
    36421 ataagaaaga aaggtgattc ctgtttccgc ccatgagcct gtcaccagag aaaagactag
    36481 aacgaccgct agttttccaa gattattcaa taaaacttct aagacaaatt ttacttggac
    36541 atacaccata tcttcttccg atttgtctcc gctgaataag gcttctaata atttgttcac
    36601 aactttatct ttcatctcat acgtacctcc accacaaatt ttatgctaaa aaaaataaaa
    36661 aacgtctttt gtttcataaa aagtggtttt gacatcaaaa ccgtcatgat ctcctaaaaa
    36721 aatcttcgtt ttccaagaac cttaccaaaa aaagtgacag ttttgatacg aaaagtactt
    36781 tttatgacaa gtttgtgctt tttcgagtga tttatgttaa aaaattactg accttataaa
    36841 aggtgatgga gggattctta tggaaaatga acaattgttt gaagtcggcg aaacatatgc
    36901 atttaaatct gatttatttg aatcaccaat aaaaggaaaa atagaaaaaa tctatgaaaa
    36961 tagtgtgatg atacgtgtca tgaaatgcgc agtagaagac aatgataccg ctcataatct
    37021 gcactggcag ttagttgtac gcaaatcaag tacaatagaa gaataaaaac agataaaatg
    37081 ttgagagcat aaagaggttg tgagtctccc gtttagctct gagttacaag gaataatgtt
    37141 aaaaaacagc ttttcatgtt ttatgaatat tgccttgtga ccgaggtgtt ggcaggagaa
    37201 tactgtttat ttgaaaaaag ggctgcgaca agacttttgt cacagccttt attttcatga
    37261 ataggagtta cttttggcta cttttagaga agtagctttt aaggagcaga taaagtcaag
    37321 gcttttattt ctataaatga agtagtaaaa tgaagaacag attttattac aggaaggatg
    37381 ccgataattg tgatcattgt tgcaggaacg atcggtgcag ggaaaagcac actaactgaa
    37441 atgcttgccc aagatttaga aacaaaacct ttttatgaga acgtggaaga taatgaagta
    37501 ttgccgctat tttattctaa tccagaaaag tatacttttt tattacagat tttctttttg
    37561 aacaaacgct ttttggcaat caaagatgct ttcagccatg atgacaacgt actagaccgc
    37621 tccatctacg aagatagtat gctgtttcat ttgaatgcag atttagggcg tgtttctgaa
    37681 gtagaagtaa agcagtatga aggtctttta gaaacgatgc tgaaggagtt agaagaaatt
    37741 tcgccacaaa agaaaccaga tctactggtt tatattcgtg tatcctttga aactatgtta
    37801 gcgagaatca aaaaaagagg ccgggaatat gaacagctag aacaagatcc tgaactctat
    37861 tcctactata aagaactcaa tcgacgatac gaagagtggt atgaacagtt tgatatatgt
    37921 cccaaaatag tgatcgatgg ggacaaatat gatttcgtag ccgatccggc atgtggagaa
    37981 caaatcgtac aagaaatcaa gatgcgggca aagaaaatga cagaagaggc agatgcccag
    38041 tcgatccgct acactacaaa taacccgaaa gcaaagggaa tctttacaac taaataatat
    38101 aaaaactaag caaattgctc actcgcagat atttctctgt gagcagcatc ttgcttagtt
    38161 tttttgattc attgagatca aatagtgaac cgattcgtat gataaaattg ccataaatga
    38221 aatgtctgag tgagggccat gatcaaaaat aaaatggaaa cgatcaaaat cgaatgggcg
    38281 ccaaacagat gatgacagaa aacaaggaca atagctcctg cgataaaggc aagaacgaca
    38341 cttagatagt ggaaaaatcg atcaaaatct gctttttctt tagaaataca ataatcatat
    38401 aagttcgttg ctaccccttt taaatttcca gttgtaaata aattagtgta ggcacgcccg
    38461 ttgattttat caaaagctac ccactggatc gatgcagtaa aagcaatcaa aatcgttact
    38521 aatgcgggat gctcatggac gggtgtcaaa ctaacaaaga aaaaaatcac tgcttcataa
    38581 tatagaacaa acaagcgcca gaaatgtttt tctttttttc taaaataatc aattagatac
    38641 tttgttagaa gaatccctaa gaaaaagaaa agggtagaca atactttttt accaacactt
    38701 agccattctc cgtcaaatgc ttggatgatc gatagaatga tattgccagt ttgagcagag
    38761 gcaaaagcac catattggat ataagtataa ctgtccatgg ctcctccgat aaatgtcagc
    38821 aaaagtccta ttgtacgccc ctcgtgaaag gaagtctgca tttttttcat caccttttat
    38881 gaatattttt gtcttcctta tcttagcata aacgattgaa aaaaaaagga aaaattttca
    38941 gaaaactaaa atcatatcgc ttcccatttt catttttaga aaggtctgtt agtataaaga
    39001 aaaaatagac aacgaaactt taaataacca acttgaaata aacaaattca aagaagaaag
    39061 atgggaagga aatcaatcag ttgaatgaaa aagaaattct ccgattacaa aaagaattga
    39121 aacgctggga gaacaagtat aaaaagcttc aacaagtctt tcggctacaa gaagaaatca
    39181 ttgctaccta tgaagcggct tatggcgaag cacccggact tattgaggaa gaagtacaag
    39241 taaaagaaag tgaaggaaac agctctttct ttaaaatgat ggagaaacgt tcctataatc
    39301 gcttcaatca agaacaaaaa gcagctatca catatgatat gaagaaacat cttcgaatca
    39361 tagcaggagc tgggagcggc aaaacgcaaa caatctgtgc aaaagctgtt tatctgatga
    39421 cgcaaaaaca agtagacgaa gaacgcatac taatgatcac ttttacaagg aacgctgcaa
    39481 atgaactaaa aaaacgagta gataatttca gccagagaaa aaccgctgtc catatcggaa
    39541 cattccatag tatctttttt aggatataca atgaaatttg tcgaaaattt cctgaagtag
    39601 caatgcaagg aatacaagga gacttttcaa aggatactgc acaaaaagtg aatgctgttt
    39661 tgcaacagct gatacgtaaa tataatcttt atatatttga tcaatatgga gaaaaaacga
    39721 ttgcttctcg gttagactat tggcagaata tgaacctttc agtagaagaa atggttcagt
    39781 tagttaaaga aaaatatgat tccattgata agaatgcacg acagccgata tcagaacgac
    39841 tgtatggatt gctcacggaa ctccaagaac aaaaaagaag ccagcaattg ctagagttca
    39901 atgatgtact ccaaaatctg aaaagcgctt tggagaatga ggagatccag cattatatcg
    39961 gcaaaaaata tgattatcta ttcattgatg aatttcaaga tactaatcca cttcaatggg
    40021 aaatcgtgaa acggatgaca aaggaaaaca ggatcaagtt gattgttgtt ggagatgatg
    40081 atcagagtat ctatggattc agaggatcag agccagcata catcaagaac tttgaaaaag
    40141 aatatcctac caaaactctt ttcttattaa ctaattatcg ttctcgggca gctattgtcc
    40201 aaggagcaaa tagattgatc agctataata aaaatgatcg gataccaaag gcgatgattc
    40261 cagcacaaaa agaagcaggt gttatggaag cctatttgtt ttctgatact aaagcagaaa
    40321 gtcagtggct aatcaaacaa attcagacat ttattcaaaa aaatgggaaa tataaggaat
    40381 caatcatatt ataccgatca gcttcacaaa cgcagcagct tgtccaatct ctgctgaaaa
    40441 cgaatattcc ttttgtactg gaagcagata gtccatatga aggtatcttt ggtatcaagt
    40501 ctttccaaca tttctatcaa aaaattgttc attggcaaac agcactgaat ctgcaaaaga
    40561 aaaatcaggc ctaccagcaa ttgctccggc agctgatggc agactgctac ctgaaaaaaa
    40621 gtgaatgcga tcaatacttt tctcctaaat atcaaaatat agccgttgca gattatattt
    40681 tgtcgataag ccccaattta aaatcgaaat ctgcagaaat ccgagagttt gaggaagcgt
    40741 tgcgtaaaac agaccagcat caagaaatct attcgcttgt tcaaagctat cttcatctgc
    40801 cacgtatagc taaggaaatc gaccagagtg atcaagaatg gatacgagaa gaagtaaagc
    40861 agcatgctac tttcagaaga ctccaagcct tatcgcaaga aacccaagcg acagctaaag
    40921 aattaaaaac ccgcttgatt gcttacagac aaggaaaact tgatgcacta tgtatccaga
    40981 gcattcacaa aagtaaaggt cttagttacc gaaatgtctt tttgattggt tgtaacgaag
    41041 gaagtttgcc ttataacgga gcgacagaaa agaaagtaat cgactttaat gaaataaaag
    41101 cagaaccagt aacgacgata gaagaagaac gaagactatt ttatgttgcg atgactagag
    41161 caagaaatcg tctgtatcta tgtgtacctc aaatgaaaaa ttcaagaaaa ttgaaagtat
    41221 cgagatttat caaagaaacc gggagtcgtg tgaaaaaagg aaagtgatag aagagagggt
    41281 gtgacagaag tggtcagttt caagaaagaa gaaggaatgt acgaaaattg cttctcaaat
    41341 ttttgtgaaa tttcagctta ttttcgaaga agctatttct ggaacacagt ttattcggaa
    41401 aagggaggtg tgacaagaat tttgtcacac ctcccttatt tattttgaaa atgagaatac
    41461 tattatcaaa atagagaata tatagaaaaa ttctcattat tcaaacgtaa ataatcagtt
    41521 att
//
LOCUS       DAYYEF010000021        39210 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000021 DAYYEF010000000
VERSION     DAYYEF010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.021"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..614
                     /locus_tag="ACHA1B_001274"
     CDS             <1..614
                     /locus_tag="ACHA1B_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFM8702049.1"
                     /translation="VFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVGK
                     YMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGTG
                     VFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPFI
                     LALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            611..1384
                     /locus_tag="ACHA1B_001275"
     CDS             611..1384
                     /locus_tag="ACHA1B_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HFM8702050.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1381..1779
                     /locus_tag="ACHA1B_001276"
     CDS             1381..1779
                     /locus_tag="ACHA1B_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030234 - enzyme regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HFM8702051.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1964..2635
                     /locus_tag="ACHA1B_001277"
     CDS             1964..2635
                     /locus_tag="ACHA1B_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702052.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2694..3134
                     /locus_tag="ACHA1B_001278"
     CDS             2694..3134
                     /locus_tag="ACHA1B_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702053.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3146..3814
                     /locus_tag="ACHA1B_001279"
     CDS             3146..3814
                     /locus_tag="ACHA1B_001279"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004619 - phosphoglycerate mutase activity
                     [Evidence IEA];
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HFM8702054.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3878..4501
                     /locus_tag="ACHA1B_001280"
     CDS             3878..4501
                     /locus_tag="ACHA1B_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HFM8702055.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4557..4943
                     /locus_tag="ACHA1B_001281"
     CDS             4557..4943
                     /locus_tag="ACHA1B_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HFM8702056.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5156..6547
                     /locus_tag="ACHA1B_001282"
     CDS             5156..6547
                     /locus_tag="ACHA1B_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HFM8702057.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            7158..7526
                     /locus_tag="ACHA1B_001283"
     CDS             7158..7526
                     /locus_tag="ACHA1B_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HFM8702058.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            7706..8647
                     /locus_tag="ACHA1B_001284"
     CDS             7706..8647
                     /locus_tag="ACHA1B_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HFM8702059.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            8716..9447
                     /locus_tag="ACHA1B_001285"
     CDS             8716..9447
                     /locus_tag="ACHA1B_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFM8702060.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            9591..11771
                     /locus_tag="ACHA1B_001286"
     CDS             9591..11771
                     /locus_tag="ACHA1B_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Tex family protein"
                     /protein_id="HFM8702061.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            11791..12273
                     /locus_tag="ACHA1B_001287"
     CDS             11791..12273
                     /locus_tag="ACHA1B_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HFM8702062.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            12289..13050
                     /locus_tag="ACHA1B_001288"
     CDS             12289..13050
                     /locus_tag="ACHA1B_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFM8702063.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            13181..14515
                     /gene="murC"
                     /locus_tag="ACHA1B_001289"
     CDS             13181..14515
                     /gene="murC"
                     /locus_tag="ACHA1B_001289"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008763 - UDP-N-acetylmuramate-L-alanine
                     ligase activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HFM8702064.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            14822..15307
                     /locus_tag="ACHA1B_001290"
     CDS             14822..15307
                     /locus_tag="ACHA1B_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="HFM8702065.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            15300..15983
                     /locus_tag="ACHA1B_001291"
     CDS             15300..15983
                     /locus_tag="ACHA1B_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HFM8702066.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            16109..18754
                     /gene="polA"
                     /locus_tag="ACHA1B_001292"
     CDS             16109..18754
                     /gene="polA"
                     /locus_tag="ACHA1B_001292"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HFM8702067.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            18799..19635
                     /gene="mutM"
                     /locus_tag="ACHA1B_001293"
     CDS             18799..19635
                     /gene="mutM"
                     /locus_tag="ACHA1B_001293"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008534 - oxidized purine nucleobase
                     lesion DNA N-glycosylase activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HFM8702068.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            19599..20228
                     /gene="coaE"
                     /locus_tag="ACHA1B_001294"
     CDS             19599..20228
                     /gene="coaE"
                     /locus_tag="ACHA1B_001294"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Dephospho-CoA kinase (CoaE) performs the final step
                     in coenzyme A biosynthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004140 - dephospho-CoA kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HFM8702069.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            20280..20612
                     /locus_tag="ACHA1B_001295"
     CDS             20280..20612
                     /locus_tag="ACHA1B_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFM8702070.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            20924..21415
                     /gene="nrdR"
                     /locus_tag="ACHA1B_001296"
     CDS             20924..21415
                     /gene="nrdR"
                     /locus_tag="ACHA1B_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0140110 - transcription regulator activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HFM8702071.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            21438..22811
                     /locus_tag="ACHA1B_001297"
     CDS             21438..22811
                     /locus_tag="ACHA1B_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFM8702072.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            22811..23737
                     /gene="dnaI"
                     /locus_tag="ACHA1B_001298"
     CDS             22811..23737
                     /gene="dnaI"
                     /locus_tag="ACHA1B_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HFM8702073.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            23866..24306
                     /locus_tag="ACHA1B_001299"
     CDS             23866..24306
                     /locus_tag="ACHA1B_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HFM8702074.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            24450..25151
                     /locus_tag="ACHA1B_001300"
     CDS             24450..25151
                     /locus_tag="ACHA1B_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine(22)-N(1))-methyltransferase TrmK"
                     /protein_id="HFM8702075.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQNPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            25148..26269
                     /locus_tag="ACHA1B_001301"
     CDS             25148..26269
                     /locus_tag="ACHA1B_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0051540 - metal cluster binding [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HFM8702076.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            26284..27516
                     /gene="pepT"
                     /locus_tag="ACHA1B_001302"
     CDS             26284..27516
                     /gene="pepT"
                     /locus_tag="ACHA1B_001302"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0045148 - tripeptide aminopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HFM8702077.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            27648..28556
                     /locus_tag="ACHA1B_001303"
     CDS             27648..28556
                     /locus_tag="ACHA1B_001303"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFM8702078.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            28591..28863
                     /locus_tag="ACHA1B_001304"
     CDS             28591..28863
                     /locus_tag="ACHA1B_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HFM8702079.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            28874..29920
                     /locus_tag="ACHA1B_001305"
     CDS             28874..29920
                     /locus_tag="ACHA1B_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhN family protein"
                     /protein_id="HFM8702080.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            30171..32780
                     /gene="clpB"
                     /locus_tag="ACHA1B_001306"
     CDS             30171..32780
                     /gene="clpB"
                     /locus_tag="ACHA1B_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_process: GO:0009408 - response to heat [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HFM8702081.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(32931..33617)
                     /locus_tag="ACHA1B_001307"
     CDS             complement(32931..33617)
                     /locus_tag="ACHA1B_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702082.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(33595..34089)
                     /locus_tag="ACHA1B_001308"
     CDS             complement(33595..34089)
                     /locus_tag="ACHA1B_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFM8702083.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(34109..35329)
                     /locus_tag="ACHA1B_001309"
     CDS             complement(34109..35329)
                     /locus_tag="ACHA1B_001309"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8702084.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            35476..37311
                     /gene="lepA"
                     /locus_tag="ACHA1B_001310"
     CDS             35476..37311
                     /gene="lepA"
                     /locus_tag="ACHA1B_001310"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="translation elongation factor 4"
                     /protein_id="HFM8702085.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            37507..38418
                     /locus_tag="ACHA1B_001311"
     CDS             37507..38418
                     /locus_tag="ACHA1B_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702086.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
BASE COUNT        13112 a         6752 c         8454 g        10892 t
ORIGIN      
        1 ttgtttttgc accgttagaa ggagaagacc tcgcttcatt tctggttggt gcggcaatca
       61 tgatgatcgg aatgacgctc tttttgtttg gagcagatta ttctatgatg gaagtcggag
      121 atctagtagg gaaatatatg atcaaaaaga aaagtttgac cgttttggtc agtttgggat
      181 ttgctatcgg gatcgtgatc acgattgctg aaccttccgt gcaagttttg ggacaacaag
      241 tatatgatat atctgacgga gagattggca gagtgttgct gattgggatc gtcagcgtcg
      301 gcactggagt atttctagcc tttgcgctgc ttcgggtcgt attcaagcta tcctattatc
      361 aattgatggc tataggctac ataggcgttt tgatcgcctc atttttcacc agttccgaat
      421 ttatgccgat tgcttttgat tcggggggag tgactactgg tccagtaact gttccattta
      481 tcttggccct tgccggaggg atgactagta tgatcaaaca aaagaaaaat gaaaatgaca
      541 gttttggaat ggtcggtatt gcttcgttag ggccgattct tgccgtgatg attttggggg
      601 tgatcttcca atgagtttct ggcagcaagt gatagatgga atcgaaatcg ttaccatgga
      661 agtcattttg gcagtggcac ctatcgtaat cctatttgtt ttaatgaata tcattagttt
      721 tcgtatgcgc aaaaagcgtt tctttgacat tatgaaaggt ttcttgataa cgactattgg
      781 gttgatcctt ttcctgcacg gagtcaatat ggcttatgta ccggtaggac agcatttagg
      841 cagtgctatt gcgggattgc cttacaatta tatactggtt ccccttggct ttttaatggg
      901 gttcttagta gggtttgctg agccggcgat tcatgtaatg atcaaacagg ttgaagaatt
      961 gagcgagggg agaatccgat cgaaaatcat gctgatggta atttcaattg ggatcggcgc
     1021 agcagtagga ttgtctatgt ggcgtttgct cgtcggattc tctctttatt atttcttgat
     1081 cccaggatac gggctagcat ttattttagg acgaaaagtg gacaagatct ttttagcaat
     1141 ggcttttgat aacggtggag tagcaacggg cccgatgtgt tcgacattta ttttatcaat
     1201 gagcgtggca atcgctgcac aaattgaagg aagagatccg atcattgacg ggtttggtgt
     1261 ggttgcaatg attgcattga caccaatatt atccacttta gtactaggat atatttataa
     1321 acgaaaagat gaaaaagaca gaatcgaaaa agaaagattg caaaaattgg gggaaagcaa
     1381 atgaaagatc ttgtagcatt gaatcttcac atgattgtga cgatcgttga cggaggaatg
     1441 ggcgaagatg ttatcgactt ttcaaaagaa gcaggtgcag caggcggaac gatcttacat
     1501 ggaagaggtt ctggtgtaca tgattcaggg aaatttttag gtttggacat ttcgccagaa
     1561 aaagatattg tgttgacatt agtacccgat agtttgacga ataaagtaat ggatgcgatt
     1621 ggtcaaggca tcaacatcga tattccaggt aatggtattt gttttagtat tgatgtagac
     1681 aaagtcattg gtatcactaa gattcatcaa tatcgagaaa ttatcggaat gcaagaactt
     1741 ttagatgaaa ataacgatag agaaaagtct gaatcataga caagcgtttg aagaggaaat
     1801 aaacacaaac aagaaggcgg atgagcgtta tttccgcttt tttgtttgta tttttctcgt
     1861 gaatacttat gaaatagtaa atttttatga aattctactc taagcatcag actttctttt
     1921 caaaatatgc tattttaaaa atgatgaaaa aagggggaga aaaatgaatt ttttagttgt
     1981 tttaaaagat actctgattg agcgatttac atttctatat gttcaattgc aggaaaataa
     2041 aacattgctg catttttcac cagagttcca tctagagggg ctaacattag gagaaatcta
     2101 tcaagcagaa gggctgtcgg ctgttttgca cttttttaag gtagaattgg aattaccagt
     2161 aaaagattat atcgagcttt ctcttgaatc ttgggatcga gcagtggttg aactgtttcc
     2221 agaaggttta atgatcgata caaacgatgg gaagatccat ctgactgcag cagaactgca
     2281 aaaacaaatg cgttatcaaa tagatgacga aaattctttt tctattttta gacgtcagca
     2341 aaagattcta aaaagctttt taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac
     2401 acagctgttg aaaaaatatc caggtctgct tcacacgtct attcaatttc ctcaattgat
     2461 tacgatgatc catcgtttta tacgtatgca acagctacca tctaagaagc tgtttcttcc
     2521 attgacggac acatttcgag tagtcaacag agaagataaa aagaaagtga ttgtgattga
     2581 ctttaccaga aatcggaatg tccttcacca agttgcaatg gaaaaggcca attaaggctt
     2641 tttctttttg gatttttttg tcataataaa tattagatga tggaggagat aatatgatgc
     2701 aaacatggtt agaaaggcta atacgatttc agcagaacta tcacaaactt atgcagggaa
     2761 gatatgcgaa atttgatcag ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt
     2821 tgctaagtcg ttggttgccc tatagaatcg gacaattgtt gttcatcgtc tttttcggat
     2881 ggatgatatt tcgtttccta tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt
     2941 atttgaaata tcttgataga gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag
     3001 tcaaaatgga tcgaaaaagt tatacttttt ttgagtgccc gaattgtcat caaaagcagc
     3061 gtgcacctaa aggaaaagga cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg
     3121 aaacgaatgt ttaagggaga aaagaatgaa attagtatta ttacgtcatg gcgaaagcga
     3181 agcaaatttt gaaaattact ggacaggatg gctagatgtc gccttaacag aaaaaggaaa
     3241 agaacaagca gcagttgccg gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt
     3301 ttatacctct gttttgaaac gtgcgattct taccggacaa gtcgcactag aagaaatggg
     3361 tcagttatgg cttcctataa taaaaacatg gcgtctaaat gaacggcatt atggggatct
     3421 tgtgggtaaa aacaaagata agatgaaaga aatatacgga aaagatcaag taaaaacatg
     3481 gcgcagagga tatacggaag ttccgccgtt aaccgcagaa aatagatttg accgcagata
     3541 tgatcacttg gatccgcatt tgatcccata cggagaaagt ctggaaatga cagtgaatcg
     3601 gatcattccc ttatggcaag atcatctagc accaaaacta aaagatcggc aagatttact
     3661 agttgtgggt catggtaata gcatccgagc actgacaaaa tatttagaag atgttcctga
     3721 agatcaaatg gatacgatcg atatcccaaa tgcacaacca atccagtata cattagcaga
     3781 tgatttgaca attctggaca aaaaaatact ttaaagaaca cctttatcta aaagtgagag
     3841 atagaaaaaa gaagcaaagg aatggaacaa aaggaacatg aaaaattata tatgggactt
     3901 tgatggtaca ttgtttgata cgtatcccgc aatggtagat ggtgcatggc aagcactaaa
     3961 agattttggt atcagtatgg acaaaaaaga aatctacttc aaaatgaaaa agtattctac
     4021 tagttatttg atcaatgaat caaacttgaa tgccagagag tttaatgaat tatttcaccg
     4081 atatgaaaaa gaaagtacgg aagtttcccg tccatttcca gaaacgaaac aagtactgga
     4141 aatgctaaaa gacaacggcg gtcgtcattt catcctgacc caccgtttga cagaatcaac
     4201 atggggcctg ttaaaagaac atcgattggc acatctgatt gaggaagtag tagggatcga
     4261 tcaggacttt cctcgtaaac ctgatccagc atctttaaat tatttgatcg atacttttca
     4321 tttagaaaga acagacacga tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa
     4381 aaatgcagga gtcgctactt gtctttacga catcgatcat tttctgggtg agatcccggc
     4441 agattatgtg gtaggaaatc tgaatgaaat ccttaccttg cagagcatca ttaaaaagta
     4501 gtatcccctt tcaaaggaga tatgttataa ttttcataaa ggagtgataa aattatatgg
     4561 aaatcagaag acaaaaagaa gttgtagaag catttcatta tgatatgaga ttgccgaacc
     4621 aagaagtaga aacagatttg aaagtaggct tctcgccttt aaaagaaacg atcgaaaact
     4681 atccgaaaga acatagcatc gtaggagcac gcttagagtt ccgtttagtg tttgatacat
     4741 atgttttatc tggaagtgtg agtcagatca atcatatcct caatcggaaa attgaaggtc
     4801 aaaatgatgt cacacaagaa gaagtggacg agctagtagc accgttattc gatatcgtac
     4861 gccgaatgtc ttatgaggtg acagagatcg ccttagatca gcctggggta aaattgaatt
     4921 ttcaatcaga aaaacaagaa tagacagtaa aaacatacct gcgatagatt aaagctatca
     4981 caggtatgtt tttttattac taattgtaag caaaaagaat gtcatttcga taaaaatcgt
     5041 ctaaaatata aaagtcactg aaaaaaattt tttcaggagg atggttgaag aatcattctc
     5101 gggaaccttt acttccttcg atggacttgt cattaataat atgaggagga gaaaaatgac
     5161 aacactcatc acagttttag tggttctagt ttttgcggca ttattatatg tgttctatcg
     5221 tatgcaaaag cgccatacaa aattttcaac acgcgtcttt acagcattag gagttggtat
     5281 cgtctttggc ggtctgcttc aattgatctt tggtgtagac gacaaagtcg ttactcaatc
     5341 aatggaatgg atcgggattg taggtcaagg atatgtatca ttcttgcaaa tgctagttat
     5401 gcctttagtg tttatttcga tcattggtgc attcacaaaa atgaaagttt ctgaaaagct
     5461 agggaaaatt agtgcgactg tattgacttc tttacttgga acaacagcta ttgcagcatt
     5521 gatcggaatt ggttcaacaa tgctgttcgg actccaagga gctaaattca cacaaggagc
     5581 tgcagaaaca gcacgaatct ctgaactggc aacacgtcag gaaacagttg aaaacttatc
     5641 gattccacag cagattttat cctttatccc taaaaacgtt tttgctgatt tagcaggtag
     5701 tcgtgcaaca agtacgattg gagtcgttat tttcgcggca tttgtcggaa tcgcttatct
     5761 aggcgtgaaa agaaaagcgc caaaagaagc agcattcttt tcagatttag tcgacagtct
     5821 gtataaaatc attatgcgga tcgtgacgct tgttttgcgt ttgacacctt atggagtatt
     5881 tgctttgatg acaaacgttt tggcaacaag tgattttgca gctatcgtca atttaggtaa
     5941 atttgtcgtt gcttcttacg tagcattgct tgctgttttg attgtccact cactgatttt
     6001 gattggtgca aaagtcaatc caatcaacta tttcaaaaaa gcctttccgg tattgagctt
     6061 tgcgtttact tcacgttcaa gtgctggagc tttgccattg aatatcgaga ctcagacaaa
     6121 agctttagga gtagatgatg caacagctaa tttctcagca agttttggtt tgtctattgg
     6181 acaaaacggc tgtgctggcg tttatccagc tatgttggca acgatcgtcg caccagcagc
     6241 tggagtgaat gtctttagtt tggaatttat tttgatgctt gtggcaattg taacaatcag
     6301 ttcttttggt gtagctggag tcggtggggg cgcaacattt gcttcactga tcgttttagg
     6361 ggcaatgaac ttgccagtag caatcgttgg gttagttatc tctgttgaac cattaatcga
     6421 tatggcacgt acagcagtaa acgtcagcgg tagcatggta gctggtatcg tgacaagtgc
     6481 acgcatcaaa gatttagatc gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa
     6541 tgcatagtca aaaagaggtt gtgatagaag tggtcagctt taagaaataa gaagaagttt
     6601 cctaaaaata gtttctcaaa tttttgtgaa atttcggctt atttccgaga agctacttct
     6661 gaaacaccgt gaataagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
     6721 aaacaaaaat agttcctcat attttacgtt tggttgagct tattaccgca gatgcaagct
     6781 tttgaacacc gtttaagaaa gaggtcgtga gcctgccgtt tcactctgag tcacaaagag
     6841 caatttcaaa aaatagcttc tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg
     6901 tcaggagaac accgtttacc agaggttgtg acttgttttt agtcacgacc tcttttttta
     6961 tttattccat ataaatacac attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac
     7021 aaccaactta tttattatta aagaaaagcg tatttaagta ggacgattct gttgagagct
     7081 ttcgtagatt ttcccatttt cctatggtaa actgacaaag ttgagaatgt tagaacagat
     7141 cgtttaggag gaaacagatg tttacgaatg aaataaaaat catgctttat gtggacgatg
     7201 tagaaaaaaa tgcaacgttt tggagagcag ttggctttgc ggaaaaagat cgtcaagaaa
     7261 tggatgggac gcttataatt gaagtaggag ttgaggacag tcaaacctca tttctgttat
     7321 atgatcgagc atttgttgag tcccattcac ctggcacagc tactagtgcc ccatctttga
     7381 tgttttacag taaagatatc tttggactat ataaaaaaat gcagacgcaa tcagtcacat
     7441 taggtgatat ggtacagctt ggagaagaat atgtctttaa ctttgctgat cccgatggca
     7501 actactttgc ggttacaggt aaataataga aataaagact ttgtttttct gtgcgaaaca
     7561 ggaaagcgaa gtctttttaa ttcaaataat aatattatgt aaacaaaaaa ctttccatgc
     7621 gtaattatac acaagcaaat aaatcgtcaa atgcgaacgc cttctttata ctgtttagga
     7681 acgaaaagaa ggaaggaaga aatacatgga ttatcaagta ctgctttatt acaattatac
     7741 aaaaatcgaa gaaccagagg aatttgccaa aaatcattta gccttttgca aatctttgga
     7801 tcttaaaggt cgtattctag tagctgaaga aggaataaat ggtactgtgt ctggaaccgt
     7861 tgaaaacacg actgcctata tgaaagcaat gaaagctgat cctcgatttg ctgatacgat
     7921 gttcaagatc gatccaagcg aaggacatgc ctttaagaag atgtttgtaa gataccgtcc
     7981 agagcttgta agtttaaagc tagaagagga cattgatcca aaccaagtga caggtgccta
     8041 tctttcaccg caagaattta aagaagctat tttagatgaa cagacagtgg tgattgatgc
     8101 acggaatgat tatgaatatg acttgggaca ttttcgaggg gctgtacgcc cagatatacg
     8161 cagttttcga gagcttccag actggatccg cgagcacaaa gaagaattta tggaaaaacg
     8221 ggtagtgacc tactgtactg gtggcattcg ttgcgagaag ttttctggtt ggcttgtccg
     8281 tgaaggattc aaagatgtcg gacagctgca tggcggtatt gctacttatg gtaaggatcc
     8341 tgaagtccaa ggagaattat gggacggcaa gatgtatgtg tttgatgaac ggatcgctgt
     8401 cgatatcaac caagtagata aacaaatcgt cggtcgcgac tggtttgacg gaacaccatg
     8461 tgaacgatat atcaattgta gcaatcctga gtgcaatcgt cagattcttg cttccattga
     8521 aaatgaagaa aaacatttag gagcatgtag catagagtgt gcgaaacatc cgcgcaatcg
     8581 ctatgttcaa gaccatggaa tctctccaga agaagcagaa ctgcggttta cagctttaat
     8641 taaatagaaa acaatagttt tgattgtcga ccatttccaa tatgcgctat actagcgttg
     8701 aggatggtga tccacatgaa atcattgatt tatgctattg gggatgtcca tggcaaacat
     8761 gagctttttg aaaaacttat tcactattat gatccaaaga tccatcagct tgttttatta
     8821 ggggatctca atgatcgagg tcctcgtaca aaagaatgtt ttttattagg aaagcaatta
     8881 gtcgaagaaa caggagccat ttacctccgg ggaaaccatg aagaatattt tttgcaattt
     8941 ctgcaatcac cggaggactg gtatgcgcct tatatgagaa atggtggaaa agaaacgttt
     9001 gaaagcctga ttcacccagg ggcatcggag gaatactccc caactgaaat ctcgatgatg
     9061 atccaatcga gatattcaga actgattaaa tttttagtcc agcgcccctt gtattatgaa
     9121 tgggaaaatt atctttttgt ccatgccggt gtggatttga caaagaaaga ctggcgtaag
     9181 acaagtctaa gagactttat ttggataagg gaaccatttc atgaagggaa aaacaataca
     9241 ggtaagacaa ttgtatttgg acatacgatt acaccaatgc tccatggaga tatgcagaca
     9301 acagacctct ggattcagga tcataaaatc ggaatggacg gtggggctgt attcggaggg
     9361 tcattgcatg gggttgtttt tgacaaggaa ggtattcttc aagatattga atatcagaac
     9421 aacgaaggac cttggcatgg aatctgacta atggaaagaa tgaaggagct gtgactttgt
     9481 tgcggctctt tttattttta tagagaatat tgtttctttc agtagtttaa cccaggataa
     9541 aaagtatgat agaataaaga agcaattttt agcagaaaag aggcatttta atgacggaaa
     9601 atttgaacca gacgatcatt cagcttgtac aaaaagaact ttcagactat cgtcctaagc
     9661 agttgactac tgtacttaat ttgttaaatg aaggaaacac tgttcctttt atcgcgcgtt
     9721 accgaaaaga aatgactgga agtcttgatg aagtccagat tcgtgaaatc gaagagcggt
     9781 atgcctatct tgaaaactta gaaaaacgta aaactgaagt gattcggcta atcgatgaac
     9841 aagggaaact gactcccgag ttagaagcag aaatcaccca agccgtgaaa atgcaacaag
     9901 tggaagattt gtatcgtcca tacaaacaaa aacgacggac aaaagcaacg attgctaaag
     9961 aaaaaggact tgaaccactc gcgaagtggc tgatgcagct tacagatgga gaggtgcaat
    10021 ctgaagcaga aaaatatatt gacaaagaaa aagaagtctc ttctgccgaa gaagcgttgc
    10081 acggtgctca tgagattatt gctgaacaag tcagcgataa tgcaaaattt cggacttgga
    10141 ttcggtctta tacgtataac aaaggtatgt atgtcagcaa tgtcaaggat gagcaagcag
    10201 atgaaaaagg cgtatatgaa atgtattatg actttgcaga acccgtccat aaaatggttt
    10261 ctcatcgaat attagctact aatcgtggag aaaaagaaga tattctgaaa gtattctttc
    10321 aagtagatga agcagcaatt ttagcttact tggatcgcca aatagtcaaa aatcctgcct
    10381 ctccttcttc ttcattcgtc agagaagcct atcaggatag ttataaacgc tttattcagc
    10441 cagcaatcga gcgagaactg cgcaatgaat tgactgaaaa ggcagatgag caagcaatcg
    10501 ctattttcgg cgaaaacctc cgtaatcttt tgttgcaacc gccactaaaa ggtaaagttg
    10561 tcctgggatt tgatccggct tatcgtactg gatgtaaact agcagtcgta gatgcgacag
    10621 ggaaagtttt agcaatcgaa gttatttatc ctcataaacc tgcagcgcaa gcaaaaagag
    10681 aagctgctgg accagctttt atccaattaa ttaataaata tcaagtagat atggtagcta
    10741 tcggaaatgg tacagccagt cgggaatctg aactttttgt ggctgagcag ttgaaatccg
    10801 ccgaccataa aacctattac gctatcgtca acgaagcagg cgcttctgtt tactccgcta
    10861 gcgaaattgc acgaaaagaa tttccgcatc tacaagttga agaaagaagt gctgtttcta
    10921 ttgcccgtcg cctgcaagat cctttagctg aattagtcaa aatcgatcct aaagctgtcg
    10981 gagtaggcca gtaccaacat gacgtttctc aaaaacgttt ggctgaacaa ttggattttg
    11041 ttgtggaaac agcggttaac caagtaggtg tggatgtgaa tacagcaagc ccgcagctct
    11101 tgcagcatat atcaggattg aataaaacaa ctgcccaaaa cattgtcatt tatcgtgaag
    11161 aaaacggaga attcaccgca cgaactcaat tgaaaaaagt gccacgctta ggaccaaaag
    11221 catatgaaca agcaatcgga ttcttgcgag tccctggtgg gaaaaacatt ttggacaaca
    11281 caggtatcca tcccgaaagt tattctattg caaaagaaat attaacttca gtccaacttt
    11341 cagaaaaaga gcttggtaca gaagaagcag tagaaaaatt gacacgatta tccgtagaga
    11401 aactggctga aagcctatca gtcggagaag aaacgttagc cgatatttta gctgggctga
    11461 cacaacctgg acgagatatg cgtgatgaga tgccagcgcc cttattacgt acagatgtat
    11521 tgagtatgga agacttgaaa ccagggatgg aattgactgg aacggtccgt aatgtcattg
    11581 acttcggcgc atttgttgat atcggtgtga agcaagacgg acttgtccat atatcgaaac
    11641 tcagcaaaaa attcgtcaag catcctacag atgtcgtgtc agtaggagat atcgtaacag
    11701 tttggataga acaagtcgat acgaaaaaag gcagaatcag tttgacgatg ctttcccctt
    11761 atgaagagta acaatgagga gtaacaaaaa ttgacacaag aagaactgca gcagttagta
    11821 gaagagatat cattaaaaag cttccagctt cctttcaagc accaagcaat gttcaatcca
    11881 cgcttacgta caactggcgg gcgctatcat ttaaacgatc atcatttaga ttttaatgcg
    11941 aagctatttg aagagtcaga cgaagagacg attgcaggaa tcatcaaaca tgaactttgc
    12001 cattatcatc ttcatctagc tggaagaggg tatcagcata aagatatgga tttcaagtat
    12061 cttttgaaaa aaacaggagg gttgcgctat gcaccagcct tgacgaagaa acagataaag
    12121 atggagtatt atcgatgcca agattgttct gccacgatct gccgcaagag aagaatcgat
    12181 gtacgcaaat atcgttgtgg aagatgtcat ggagaaatca aatggattga gacaaaaaga
    12241 gaagacttta atgaagcaca aaaaatcaga tgaaaggata gaaggccttt ggaaaaaagt
    12301 gagcagagga atctaaaaga ctggaatcag ctattaaatt ttttagccgc acctgaagag
    12361 ggaaattttg aggaactgac ggcacctaca cttattttag ctggaaactg tcttcctatc
    12421 ttagctgata aagcagcaca aatgtattta aatggccaag tagatcaatt gtttttggtc
    12481 ggaggggtgg ggcatgcgac tagaatcctt tatgagaatt ttgaaaagca aggatttcat
    12541 tttgaagatg gcatgagtga aagtgaaatc tgtcgtcagt atctaaaaga agtctatgat
    12601 ttgcccgata aggcttttct gatagaatcg aagtctacaa attctggaga gaacgccact
    12661 ttttcactgg agattcttca ttccttagga gctgtaccag aaaaaatctt attgatgaat
    12721 gatccgacac tgcaacgcag gactcgagca acttttgaga aagtatggca aaatgaacaa
    12781 actattttcg cgaatgctgt gccatttgtg ccggaaatcc ttcacttttc tgaagagatc
    12841 atctttacag caaaagaact gaatcatcaa tggcctaagg aatatttcca tgcgctagta
    12901 ttaggagaaa tggaacgtct ccatgacgat gagaacggct atggtccgaa aggaaaagat
    12961 tttattcctc acattgatat atcagaggaa gtttggtctt cttacaccag aattaaagag
    13021 tcaataaaaa cggatttttc tcgtacttga ccattttagc aagcgaatcc tcctttccaa
    13081 ataaatttgg ttgaaatttt caatcgttta taagataatg aggagcgtgt tgaatgtaat
    13141 agctaaaaga atggacgcta gataagagaa gaggattcaa atggaaaatc aaaataaatt
    13201 gtatcatttt gttggtatca aaggttcagg aatgagctcc ttggctcttg ttttacatga
    13261 acaaggtcta aatgtccaag gatcagacat tgaaaaatat ttctttacac aaagagattt
    13321 agaaaaagca aatatcacga ttctgccatt taacgcagat aatgtaaaac cagggatgac
    13381 gatcattgca ggaaatgcat ttcctgattc acatgaagaa atccagcgag caaaagaatt
    13441 aggtttggaa gtgattcgct atcacgactt tattggtcat tttatccaaa attatacgag
    13501 tatcgctgta acaggctctc acggaaaaac aagtacgact ggactgctct ctcatgtatt
    13561 gagtggtgtc cgtccaacaa gttatctaat tggagatgga acaggacatg gtgatccgca
    13621 agcggaattc ttttcatttg aggcctgtga atatcgccgt catttccttg cctattcacc
    13681 agactatgca atcatgacca atatcgattt tgatcatccg gattattata caagtatcga
    13741 cgatgtattt acagctttcc aaacaatggc tggacaagtg aaaaaagcta tttttgcgta
    13801 tggtgacgat gcttatttac gcaaattaaa agcaaatgtg ccgatttatt attatggtgt
    13861 cacagaaaac gatgatatcc aagcacgaaa catcgaacgc acaacttctg gttctgcttt
    13921 tgatgtctat catggggatg aatttgttgg gcacttcact gtaccagcat tcggtaaaca
    13981 caatatctta aatgctttag gtgttattgc agtagcttat ttcgaaaaac tggatctgaa
    14041 agaagttgca gaagaaatgc tgactttccc aggagtaaaa cgtcgattca gtgaaaagat
    14101 cgtagcagac atgaccgtag tcgatgatta tgcgcatcac cctgcagaga tcaaagcaac
    14161 gattgatggc gcacgccaaa aatatccaga taaagaaata attgcagttt tccaacccca
    14221 tacgtttacg cgtacgattg cattgatgga tgaatttgca gaagcacttg atttagctga
    14281 taaagtttac ttatgcgata tttttggttc ggctcgggaa gaacaaggaa acgttaagat
    14341 tgaagacctt ggagcgaaaa tcaaaaaagg tggagaagtc atcaaagaaa ataatgtatc
    14401 tccattgtta gattatcatg atgcagtagt aatcttcatg ggtgctggag atgttcaaaa
    14461 atttgaacaa gcgtatgaaa aacttttaag cagcacgacg aaaaatgtac tgtaatacaa
    14521 ttactgcagt gtccttataa aaatagaaag agggggagtg gcaaaaatct tgccaagccc
    14581 ccttttttgc aacttatgat aaacggtgtt caaaagcttg catctgcggt aataagccca
    14641 atcaaatcaa aaacatgaga agctgttttt tcttggctgt tcttattatt tgatgcagga
    14701 cagctttttc acgacctctg taaactatag gaatctgtta aatcaaggga gcagaacttg
    14761 ccttttacgc tacttttggt acaataatgt atgattaaaa ataaactgga gggtttctat
    14821 cttgaacata ggtaagccga gaaaactagg aaaaacaata aatgaaatcg aggaaggcga
    14881 ctcgttatcc ttaacagaat ctattgaaga taaccagctt ttgctgtatt tgggattgac
    14941 gaatgatgca aatcctttgt atatccaaca tgactttgca caaaaaacag aatatcaaca
    15001 gccaatcgtt ccatcagtga tgctgatggg gatcatcaca agtgcaattt caaagcatct
    15061 tcctggacca ggatcacatg ttgtcaattt ttctgtcaat tttattgaac cggttttcca
    15121 ttatgaaaca ctgacttttc agtttgaggt cataaaagta gataagatga aggatgtggt
    15181 gacgatttct gtagaagcgg agaatacgaa cgaagatcgt gtgttggatg ctgtcgttat
    15241 ggtccaaccg ccacaagttc ctgaattgga aatagcaatc gaaagtgaag gtgaattgaa
    15301 tgaataatcc aagtacatca atgtcaggta tcaatcgttt ttatgcaaaa gtttatggat
    15361 ttttaggtat gggacttgcc cttagtgcag tcacttctta cttggctctt tgggtatttc
    15421 ctttgcaatt agcaactttt atcaataatt ttccactagg ctttgtgggt ctgtggatcg
    15481 ttgaactgat tttagtaatg gttctaggcg taaaagcaca aaagaatccg agcttagcaa
    15541 tcggtggatt tattgcctac tctcttttga atggcataac attagcggtt actcttgcat
    15601 actacgatat tggaacagta acgcaagctt tcttgacagc tactttgatg ttcatgggga
    15661 tgtctgttgt cggagtaaca acaaaaagag atcttagcgg ggttggaaga gcaggacagg
    15721 cagctttaat cggagtgatc attgcactag tcttgaacat cttcattttg agaagtagcg
    15781 tagttgagct gttcatctcc ctactgttag tcgtcatctt tgcagggatt acagcttatg
    15841 ataaccaaag catccgtaat atctatgtcc agacaaacgg aacagcacat agtggaattg
    15901 ctgtattcat ggcattgaag ctgtatttgg actttatcaa cttgttcttg gcgtttctga
    15961 gaatctttgg acggaacaac taaaaaagaa aaaaattcat cagttggggc tataccgaat
    16021 tatttggtat ggtcccgctt tttcttttcg cattccgcag gattctttgt tagaatgaat
    16081 aagaacttta cagtaaggag ttaagaagat gacaaaaaat aaattattac tcgttgatgg
    16141 gaacagtgtg gcttttcgcg cattctttgc gcttcacaat tctcttgaac gtttcaaaaa
    16201 tagaaacggt cttcatacaa atgcaatcta tgcattcaat acgatgtttg aaaatgttat
    16261 gcaaaaagag caaccgactc atgttctggt tgcgttcgat gcaggaaaaa cgacttttcg
    16321 gacagaaatg tatgcggagt acaaaggtgg aagatccaaa acacctggcg aattcaaaga
    16381 acaaatgcca tatatacgtg atttgttgac aggactaggg gtacagtatt acgaattgcc
    16441 caattatgaa gcagatgata ttatcggtac tttggcagaa aaagtagaca aagatcaatt
    16501 tgatgtcgtc gtgctttcag gtgatcggga tttgactcaa ttagctagta aagaagtaaa
    16561 agtggatatc actgtaaaag gtgtcagcga tatcgaaagc tatacaccag aacatgtagc
    16621 ggaaaaatat gatgggttga cgccaaaaca gattattgac atgaagggac tagccggaga
    16681 tgcctctgac aatatccccg gtgtgactaa aatcggtgaa aaaacagcta tcaagctatt
    16741 gaaacaatat ggctcagtcg aaggaattta tgaacatatc gatgaaatga agcaaagcaa
    16801 aatgaaagaa aatctgataa atgacaaaga gcaggctttc ttatcgaaaa aattggcgac
    16861 catcaatact tcagcgcctg tggatgtctc tatcgactca ttgaagtatg aagggaaaaa
    16921 tctcgataaa ctcgttccgt tttataaaga aatggatttc aatcagttcc tttctaaatt
    16981 gaatatcgta gaagaagaag taaaaatgga tgatattttg tttgaagtcg ttcatgaatt
    17041 caaagaggaa atgtttacta cggatatggc gttgtacgtg gaaatgatgg gcgacaatta
    17101 tcatacagag gaaatcgtcg gagtagcgtg ggggacagaa aagaaaattt atgtcacgaa
    17161 cgatctatct gtattcgaaa accgagcgtt ccattcttgg atcactgatc cgactcggct
    17221 gaaaaaagta tatgatgcga aacgaactta tgttgcttta aaccgctata ctggaaaaac
    17281 gaaaggaatc gattttgatg tcttgctagg tgcatacctt ctcgatacga atgaaaaaag
    17341 cacagatatc gaaggaatag ctgctcatta cggatacaac gatatccaat cagatgaagc
    17401 tgtatacggc aaaggggcga aaaaaggttt accagaagaa gaggaactct tttttgctca
    17461 tttagcgcga aaagtagctg caatcaatgc gttgacacca aaattgagcc aagaactggc
    17521 agaaaaaaac caagaagatc ttttccggaa aatggaactg ccattgtcta tcattttggc
    17581 agagatggaa ataagcggga tcaaagtaga tgcgactcgc ttacaagaaa tgaagggcga
    17641 gttctctgct cgcttaagag agatcgaaca aaaaatctac gaagaagccg gcgaagaatt
    17701 caatttgaat tcaccaaagc aattaggagt gatcttattt gaaaaaatgg gattacccgt
    17761 tatcaaaaaa acaaaaactg gatattccac agccgtagat gtactggaac agcttcgtga
    17821 acaagcacca atcgtagagg atatcctcac ctatcgtcaa attgcaaaaa ttcaatctac
    17881 ctatgtcgag ggactgctga aagtgatcca atcagatgga aaagtgcata cccgttatgt
    17941 ccagacattg acccaaacag gacgattaag ctctgttgat cctaatttgc agaacatccc
    18001 gattcgatta gatgaaggga gaaagatacg tcaggcattt gttcctagag aaaaagactg
    18061 gctgatttat tcttctgact attcacaaat cgagttacgc gtacttgcgc atatctcaaa
    18121 tgatgaacat ttgaaagctg ccttcctaga aggtcaagat atccatgcca gcacagcgat
    18181 gcgtgtattt ggaatcgaaa aggcagagga tgtcacacca aatatgcgta ggcaggcaaa
    18241 agcagtgaat tttggtatcg tgtatggcat ctctgattac ggactttcac aaaatctagg
    18301 aatcagccga aaagcagcac agcaatacat cgatacgtac tttgaaaaat acccaggtgt
    18361 caaagaatat atggaaagaa tcgtacgcga agcaaaagac caaggctacg tcgaaacgct
    18421 gtatcaccgc cgtcgatatc tgccagacat caattcaaga aattacaata tccgttcttt
    18481 tgcggaacga acagctatca atacaccaat ccaaggaagt gctgctgata ttttgaaaat
    18541 cgcgatgatc gaattggata aacgattaaa agaaacaggt cttcaagcta cgatgctgtt
    18601 acaagttcat gatgaacttg tcttcgaggt accggaaaaa gaacttgaat cattagataa
    18661 attggtgaag gaagttatgg aacaagctgt ttctcttcat gtaccactga tcactgacag
    18721 cagttgggga aaaacgtggt acgaagcaaa ataaacattg tttaagacag agcaatataa
    18781 tgaaggtgaa aagaaaaaat gccagaatta ccagaagtag aaaccgttcg taaaggattg
    18841 gaacggttag tagtaggaaa aacgattcaa aaagttcagg tcttgtggcc caagatcatc
    18901 gagcaaccag agacacccat ctttgaggct tctcttgttg gcgaaaccat ccaatccatt
    18961 ggacgtagag ggaagttttt aatttttcat ctcgatcatt gtgaactgat ctcacacttg
    19021 cgaatggaag gaaaatatca atttacgaaa gaaaatacac caatcgataa acatacgcat
    19081 gtacttttct tttttgagga tggaagccaa cttcgctaca acgatgtacg aaaatttggt
    19141 cgtatgacaa tcgtcgaaaa aggagcaagt gcaacttacc gaggaatcat gaaattggga
    19201 cctgagcctt tgccagatag cttcttatta gcagatttcg caaatggact gaaaaagtcc
    19261 cacaaagcaa tcaagccatt gctgctagac caacgtctag tgactggtct aggtaatatt
    19321 tatgtagatg aagcattatg ggaagcgaag atccatccag aacaaccggc gaacacactg
    19381 cgccccaaag aggtagaaca attacgtcta tcgatcattg atgttttgga tcgtgcaata
    19441 gaagccggag gtaccacgat tcgcagttat ttgaatgcat taggagaatc aggcggattt
    19501 caagtagcac tgcatgtcta tcagcaaact ggcaaaccat gtatacgttg tggaacgccg
    19561 atcgtgaaaa caaaagtggc acaaaggggg acgcactatt gtccgaattg tcaaaggcta
    19621 aaaatcgcaa agtaggattt gttttaggtt tgacgggtgg aatagctacc ggtaaaagta
    19681 cggcagccaa agtctttcag tctcatggat ttcctttgat cgatggcgat gtgattgcca
    19741 gagaaactgt tgagcctgga acgcttgctc tgaggaaaat tgtatcagtg tttggccaag
    19801 aggtattgca gcctgatggg caactagatc gagggaaact tgggatgatt gtttttccat
    19861 caaaggaaaa acggcaaaaa cttgatcagc tattagatcc gtttatccga aaagcgataa
    19921 aagatcaaat cgcctctcta agttccaatc atcctttagt aattgtagat atcccattgc
    19981 tctacgaagg tcattatgac cactatatgg atgcagtagc tgtcgtttat actacgccag
    20041 aaactcagct tcagcgtttg atgaaacgta atcaactgac gctagaacaa gcgcagcaga
    20101 gaattagtag tcaacttcca atcgaagaaa aaaagcagcg tgcggatatt ttgttcgaca
    20161 acaatggaac aaaagaaaaa cttgtgggac aaatcgaaaa ttggcttttt gctaatcgct
    20221 ttctttgagt atctgtgtca attttgctat cctgagtata tagaaagtga gggatagcga
    20281 tgggatcatt aaaaaatcaa aaggataaag tcgtaggtaa cgcaaaagaa aaaatcggcg
    20341 agatgctcaa taaagaaaat ctaatcgatg aaggtcgtac gcaatcagaa acagcagaag
    20401 aaaaagaaaa gcagtaccaa gcaagaatcg atgaaataga agaccagcag gcagaagaag
    20461 aagcgaagcg gcaagatttg actcaagaac gaaaaaatcc gacacctgat cgtagtaaaa
    20521 caccgctccc agaaagtgac cacattcccg atgagcaaaa aatcgaggaa cagcgaatga
    20581 aacactatac aggaatcgaa gagaagttat aaaatagtaa aaaatcgaga tgtgacttga
    20641 agcagatgag aaggtgttca tctgcttcaa gttttttgtg ctagatgact aaatcagctt
    20701 ttgtgtaagt tatttctcag taatcaaggt gatcagtatt ggaaaattga aatttagtaa
    20761 ggacagggga cacaattacg catgaaagta gaaaaaattg ttcttatatc cgtgtttttt
    20821 gggtaggaca gtcgcgtttg tgatttgttt cgtgttataa tacaactagt tgtaaagaaa
    20881 gacacatcct ttatataaaa tgcgatgcaa gaggtgagac aaaatgagat gtcccagatg
    20941 tcaacataat aattcacgag taatcgacag ccgtcaagca gatgatggac gtgcgatccg
    21001 tcgccgtcgc gaatgtgaga attgttcgtt ccgattcact acatttgaac gaattgaagc
    21061 tgctccgtta ttagtaatca agaaaaacgg ggaacgcgaa gagttcaatc gcgataaaat
    21121 tttaagagga ctcatccgtt cagcagaaaa aagacctgta gctatggaac aaatggaaca
    21181 aatcgtcaac catgtcgaaa accgcgtacg cagtctcgga gaaaacgaag tatcgacgaa
    21241 tctaattggt gaatatgtga tggaagattt agttgattta gacgaaatcg cttatattcg
    21301 ttttgcaagt gtttatcgcc agttcaaaga tatgtctgtt ttcttaaaag agttgcaaga
    21361 tatcgtggat aaagcaaaag aaaataataa agagaataat aaagaaaaca attaagaaac
    21421 aaaaaggagg catttccttg gaaaatgctt ggaaagagct tcaaccaaaa aatatttacc
    21481 aaggaagaaa agcggctccg ctgagagaag acagcaagaa cgccttgctg tatctttatc
    21541 agccactaat cggcggagaa gccttgagta tctatttcac cctgttatca gaaatctctc
    21601 aagaatctgg caaaggtcct gaagggatgc atgcagatct gcttagtagt ctaggctgcg
    21661 gtatcccgca attttatgat gcaagaaaaa agctagaagg aatcggctta ctggatgttt
    21721 attttaaaga agatagtgat ctgggacctc gttttattta tgagctgtta gaaccactca
    21781 ttcctaaagc atttttcaaa gactctgttc tggcttttct tcttctggaa aaagttggtg
    21841 aacgacgatt ccagaagctt acccaattct ttgaacctaa aaggcataca gcagagggat
    21901 atcaaaaaat cacaaaaaaa tttttagatg tttatcgctt caatgaagca gtgtacgctg
    21961 ctaatcaaga aaacatcgaa tcgctgaata aatcttttga agaatctgaa tcagtagcat
    22021 tacttgaagc agattcgaca ttcgattggc agtttttgaa tgattggctg gcaaaaaaac
    22081 atattgcaag tcttgatgat ccaatcatca aacaagtcga catgtatcat cagctttacg
    22141 gtttcgatga attgacactt ggcgaactga tcagtcaatc ttatgacttt agtgaacaaa
    22201 aagtatctga aaaagaactg caaaaagcca ttttggcaat gcagagacgt ccggtgaagc
    22261 aaacaaaaga aacagttgcg gtttctgaaa acagtaatga accctcgtca aacgaacatt
    22321 tgacaaacgc agcgcttcag ctgataaaag aagcacagag cattccaccg atgaaatatc
    22381 tggaagcaat caagtcagaa aaaggcggat atgtttctaa acaagaaaac tggttactgc
    22441 aagatcttgt ttctcaatca ggtctttcca gtagcgtgat caatgttttg ctgaattatg
    22501 tactagtgat caagaataat gctagcttaa atgccagtta tgtaaataca gtggcaaatg
    22561 aatgggcaca aaagaaaatc gccacagcag aagaagcgat ccagcacatt cggcaaataa
    22621 gtaatcaagc aaaacaatca aaacaaaaga agcaaacaaa ttatcaaact ggcaagcgaa
    22681 atgttcgacg ggaaaagctt cctgattggg tcaaccagcc aaaagatgaa aaacagatca
    22741 gcagcgagaa aaaagcagag attgaccgcc gttttaaaga atacctggca aaaaaggagg
    22801 gtgatatcta gtggaagacg taggcaaaga attgaagagg atcatcagca aacgcaatta
    22861 tcaagaaaag tatgctgaaa tgatcgctga agtcttaaat gatgcggatg ttcaagcttt
    22921 tctaagcgca caccaagaag aattgacaca agcggatatt gaaaaaagtt acgctaaatt
    22981 gtatgaattc gtgcaagaaa agcgtaaata tcaaaaaaac gatccaacga tgatcgctcc
    23041 cggctatgag ccgaagctga cgttgaattt tcattatgtg gatgtcactt atgtaccaac
    23101 ggaagcattg ttagcacggc aaagacaaga agaaatcaga agccgagtaa aagcaatgga
    23161 tatgccaaaa gatattcaat cggcttcttt tgaaaacttt gaacgtacag atggacgagg
    23221 atatgcgagc ttagaagccc tagattttgt agagaaatat actgctgatc caaaagggta
    23281 tcataaagga ctgtatctag taggaagttt tggtattgga aaaacatatt tattaggagc
    23341 aacagcgaga gaattagcga ttgctggatt caccacgacg ctagtccatt ttccgacatt
    23401 tgccgttgag atgaaacagg caatcggaaa agatcaagtg gcagaaaagt tagatgcagt
    23461 gaaacgttca cctattttga tgatcgatga cattggtgca gatgcgatga gtagttggat
    23521 acgagacgaa gtattcggtg ttatccttca atatcggatg caggaacagt taccaacctt
    23581 cttctcatcg aattttacaa tggatgaatt ggaacagcat ttgtccgtca ctcaacgtgg
    23641 agatgaagag ccgctaaaag cgaaacggat aatggaacgc atacgttatt tgacaaaaga
    23701 aatcgaaatg actggtcgca accgacgcaa tggttgaaca gttgacaagt ccaactgaca
    23761 tttgacctag tagtaaaagc aggtcagcga atcattatat ggacagaaat gaccggagac
    23821 aatcaccgca acaagtaatg cagaaactta aacggaggat tttttatgag ggctattttt
    23881 tctagtatat ctgtagttgg tctatttttt cttttagcag gctgcggtag cgcagatagc
    23941 aacacaggtt ctgttgattc gattgatgcg ggtcaaacag taaaaacaag cagtacgaaa
    24001 acggagagac aaagcatatt tgtcggaacg attgaaagta tcactcaagt agaagcagaa
    24061 gaagaaacgc ttcagttgaa actcgtcgat gtcatggcca aagaagatcc agcgaatatg
    24121 ggaacgtcat tcagcaatga cggagtgatc ttaaatgcta ctgctgaaaa aataagcgtg
    24181 gacataaatg aattgaaaat cggtgacaaa gtccaattta cattagttga gatgccgatc
    24241 atgacgatgt ctatcccacc gcaagttcct ggagattcga ttattgatgt ttcattgaac
    24301 aaataaccaa taacattttt tcaaaaataa gaaaatgttg ttttatagaa cgaaaaggta
    24361 tattttttaa ggagatatgg gaattttttt attcctagtc tccttatttt atttggaaaa
    24421 tgctataatt atctagaagg agtgaagcta tgaaccattt agatttatct cagcgcttag
    24481 ccgcagtggg tgactttgtc cctgaatccg ctcgtttagc agacattgga tcagatcacg
    24541 cttacttacc cgttgcattg atattaagag gaaaaatcga atatgcagtt gctggtgaag
    24601 tcgttcaagg tccttatgaa tcagcacgta agcaagtcaa aaaagatgga ttagaagacc
    24661 gtatcaccgt acgccttgca aatggtctag atgctatcca gccacaagat ggtattacag
    24721 ctgtcacgat tgcgggtatg ggaggttcac tgatccgaga tatcctagaa gctggcaagt
    24781 tgaatcaacg cttaagcgga caagaacgtt tgatccttca gccaaacatc ggagagcgta
    24841 cattacgatc ttggctgcaa gaaaatcagt ataaaatcca atcagaaaaa atacttgaag
    24901 aaaataaaaa aatatatgaa atcattgtag ccgaaaaaga acaaaaccca gttacttaca
    24961 atgaaatgga gctgatgttc gggccatttc tgcttgaaga gaaaagtgag atcttcaaat
    25021 caaaatggac aagagagctt caacaaagaa aagctatccg tgaacagctc aaacaagcag
    25081 ctaatcaaga ggcacgtcaa aaacaaatcg agcaggaaat ccaaatgatt gaggaggttt
    25141 taaagccatg acaatcagcg gacgcacttt catccaaaag tttgaaagct attgtcctca
    25201 gtggctagct gaagaaggag acccagtcgg actgcatatc ggaacattgg ataagccaat
    25261 ccaacgagta atgatgacat tagacgttcg tccagaagtg gtcgaagaag caatcaagaa
    25321 aaaaatcgat ttgctgattg ctaaacatcc tccaatcttt cgtcctgtaa aacggctggt
    25381 tactgatcag ccacaagaaa aaatgtatgc agatttgttg aaacatgata ttgccgtcta
    25441 tgcagcacac acgaacatgg atattatttg ggatggactg aatgactggt tttgtgaact
    25501 tctcggtatt gaagtggaga gttatttagt aaagactcat gagattcatt ataaaaaact
    25561 ggccgtttat gtacctgtgg atcatgcaca gaaaatgcgt gaagtattag ctgcagctgg
    25621 tgctggtaca caaggtgatt ataccggtac aagttttacc tcgattggac acggtcgatt
    25681 tactccggaa gctggtgcac aaccagcgat tgggaaagta gggaagacag aacaagttca
    25741 agaggcaaaa gttgaggtta ttttgccgga aactatcgaa aaacaagtga ttcaagccat
    25801 gcggtcagct catccttatg aggaacctgc ttatgatctt ttcgctatag atgaaccagt
    25861 cgaaatgttt gggttaggac gagtaggtga attgccgcaa gaaatttcta tagaggcatt
    25921 tgtagaacaa gtaaaagaag cgttccaact agatggactg agaatagtcc agccaaaaaa
    25981 tgcaaaatcc tctgtgaagc gcattgcgat ttgcggtgga agcggtgaaa aattttatcc
    26041 gcaagcaatc gcccaaagag cagatgtcta tatcacggga gatatctatt atcatacggc
    26101 tcatgatatg caaagcgctg ggttgattgc aattgatccc ggtcattata ttgaatcgtt
    26161 atgcaagcaa cgatttatcg agaaatttga atcttggaaa caagaagaaa attgggatat
    26221 taactttttc gtttctgaaa caaatacaaa cccatttcaa tttaattaaa aggagagaat
    26281 actatgtacg aaaatctttt gccacgtttt ttacgatatg tcaaaacaga aacacgctcc
    26341 gatgcaacaa gcaaaacgac tccatcgact cagacacaag ttgcttttgc gcaagaattg
    26401 aaaaaagaat tagaagagtt aggcttagct gatgttttct ataatgaaga taacggattc
    26461 gttatgggaa cattaccaag caatgttgat catgaagtgc gttccattgg atttatttcc
    26521 cacatggata cagcagattt taatgcagta ggagtcaatc cacaaatcat tgaaaactat
    26581 gatggcgagt ctacgatcgt actagatgcg gaagaacgct atacattgaa tacaaaagat
    26641 tttccaaatt tgaaaaatta tgaaggccac acattgatca caacagatgg cagtacatta
    26701 ctgggagcag atgacaaatc agggattgcg gaaatcatga ctgcaatgga gatcttgatc
    26761 aataatcctt ctatccctca cggtaccatc aaagtggctt ttggtcctga tgaagaaatc
    26821 ggtgtcggag cggataaatt cgatgttgag caattcgatg tagattttgc ttatacagtc
    26881 gatggtggtc ctttaggtga gttgcagtat gaaacgttta gtgctgctca agcaaatatt
    26941 acgatccaag ggaaaaatgt acatccaggg acggcaaaag atacaatgat caatgctcta
    27001 cagttagcaa tcgattttca taatcagctt ccagccgatg aagttccaga aaaaacggaa
    27061 ggatacgaag gtttcttcca tttgatggca ttggatggga atcctgaaga agcttctatg
    27121 agttatatca ttcgcgatca tgatcgtgaa aaattcgaag cacgcaaagc acaaatcaca
    27181 catatccaag aagagttgaa tcagcgattt gatcaagaac gaatcaaagt agatatgtat
    27241 gatcaatatt acaacatgaa agaaatcatt gaaaaagata tgagcatcgt ggaattagcg
    27301 aaacaagcaa tgatcgagct tggtatctct ccagtgatcg aaccagttcg tggaggaaca
    27361 gatggttcaa aaatctctta catgggtatt ccgacgccaa atctatttgc cggaggagaa
    27421 aatatgcacg gacgattcga atttgtttct ttacaagtaa tggaaaaagc aacagacgtg
    27481 attgtaaaaa ttgcagaatt gaacacaaag agttaaaatc gaaaaagaac agcttatgac
    27541 aaggcgttcg tcccaatgat ggaatgtcat ctgtctaagg ctaaagggca ggacaatgga
    27601 attggttgtc ccgccctctt ttttgaagag taaataggag gtaaagaatg gaaaagctgc
    27661 tagtttttta taacaaaagt tcagggaaag atgagggtga gaaattagca cgctggtttc
    27721 aagattatgt aaaagaaaag cagccagaat tatatgtaga actagctgaa actggcccat
    27781 cgattgatga tgcggaatta gtcaagaaag cagaagccat agaagctgat actttagtaa
    27841 ttataggtgg agacggcacg attcatcata tcgtccaagc gttccaaaaa acattatctc
    27901 aataccatgt cggattactt ccaggtggaa ctgtcaacaa ccttgcacgt gttcttgaga
    27961 ttcccctcaa aaaagaagaa gctgctgacg tgatcctgga aggcaatgta cggaaaatag
    28021 actatggtca agtcaatgat gaagtcatta tctctacact gacaatcgga atcttagcag
    28081 atacagcagt ttggatcagt caagaagaaa aacagcgtta cggctcgtgg atctttatca
    28141 agaagttttt taagttattg ctgaagaaga aaaaatatca tttggattta gaaacagacg
    28201 aggagcattg gaaaggaaaa tcccaactgt tgacagtcac gatgtctaac tccgtgggcg
    28261 gttttacaaa ttttgacgac tcagcgaccc tagatgatgg aaaatttcat gtaacgatcg
    28321 taccttcctt agatattttc cgatttattt tttatttgcc tagaatcatg agaggcaaat
    28381 tctatacgat ccccggcatt acttatttca cagccaaacg catgaaaatc caagcgcagg
    28441 aaaaatctgt gggcactcga acggatggag acacgacaga tgatcttcca gttgaattat
    28501 ctgttgtatc aaaaggatta acagtttatt caccaaagaa agaagaaaaa gcttagaaat
    28561 agtagttaac agaaagttgg aagaagagta atggatgtat tgttacacaa tcctttgtgg
    28621 ttttaccttt tcattgtgaa tttttactta ttttgtctga tggggtatga taaacatcag
    28681 gctagaacta gcggctggcg tgttcctgag aataatttga tatttgtcag cctgttaggc
    28741 ggtggtttgg gaggattgat ctctcgaaaa gttttccatc ataaaactcg gaaaaagaag
    28801 tttactatag gattcgctgc aggtgtactt gttgatttga ttctcattta ttttttccat
    28861 taaggagcag gagatgtcgt ctaaaggaac gaaaactaaa atcattctga atctgctttt
    28921 gctgattgtg atttttgcca ttatttatta tttaatcaat caatcatttg cagatatctt
    28981 tgccgaattg ctgtctacca gtgttgttgt tttggcagcg gctgttatat tagggacagt
    29041 ttaccaaatc gctgaagggc gctcaatcaa agaaattgct gaacctttcg cgccgaattt
    29101 tacaacgaaa gatgggttct tgacctctag ctatattgcg ttttaccgaa tcgtttcgtt
    29161 tggtacagga acgctgatct cggagattta tttttataac aaaaaaggaa tgaagctatc
    29221 ccagggagca ggggtgacag cactccatat gattatgtac aaactggcag tgatcactta
    29281 tgcattagct ggcttggtca tccaattctc tcttttttat tctaatggtc catcaatgat
    29341 ctggtttatc atcgctggta tccttttgac gatcgtgatt gttgcctttt tattggcgat
    29401 gtccgtcagc ttgaatgttc aaatattttt tgtcagctta tcgaataagt tatttaaaag
    29461 tgagcgtttg cggaaatggg tggatacatg caatcagcag atctactctt taagggaaac
    29521 ggtccaaacc attatccaag acaggactgc gctattgcgg atttatctat ggaatatgtt
    29581 aaaacttgta ttttggtatg tacttcctta tttgattctg attgaaaacc atcctaaaat
    29641 agattttcta ctgaccattt cgtttatcag ctttgcagta gtgctttcag gggttattcc
    29701 tacgcctgct ggtattggtt cctttgaatt tgtctatttg ttattattca gaccagttgt
    29761 tggaacagtt gacgcagttt cttcgctttt actgtatcgt ttcagttcct ttatcttgcc
    29821 atttctctat ggatttgtgt atgtgattgc tgaacggcga agagtgatca aagaagaaat
    29881 aatagaagta aaaaaagaga ataaagaaaa tcaagggtag gtcttttata agatctaccc
    29941 tttttatcaa atcaaagaaa aacgttatgg ataagataat tttacgtttg tttggctctt
    30001 tttttatata catacaatca attttgtttt tttaagattt atataagtcg agaaaaaaag
    30061 tcaaaaaact atgtgtatat tttgaccaaa attgaccaaa gcgatataat agtttttgta
    30121 aagatcaaag aaataagtga tcttaccttt aattaggagg gtatacctgt atgaatattg
    30181 agaaaatgac tacgacgctt caagaagcga ttgctgaagc tcaacagatt gcggtcactc
    30241 gaaaacatca agatatcgac attgcccatg tatggaaaat ctttttacaa tctaatcatt
    30301 ttggtcgaaa tttctatacg gatgccggat tggatgtcga atcttttgaa catgaaattg
    30361 atcgtctact ggatgagtat ccagttgttt ctggtggaaa cgtccaatat ggacaaaacc
    30421 tcagccagaa tttctttcga ttattgaatg aagcagacca aatacgtgaa agcttcggcg
    30481 acgagtttct ttcaacggaa gtcgttattt tagcgttgat gaaattaaaa aattatccgt
    30541 taactgttta tttgaataaa aacggattat ctgaaaaaga attgcgtaaa aacatcgaag
    30601 agatgagagg aggagaaaga gtgacctcac aaaaccaaga agaacaatac aaagcattag
    30661 aaaaatacgg cgttgattta gtacagcaag tcaaaagcgg aaaaatggat ccaatcatcg
    30721 gtcgtgatga agaaatccgt gatgtcatcc gtattctttc acgaaaaaca aaaaataatc
    30781 ctgttctgat aggagaaccc ggtgtaggga aaacggcaat cgttgaaggg cttgctcaac
    30841 gtatcgtacg caaagatgtg cctgaaaatt taaaagataa aacgattttt tcattagata
    30901 tgggtgcatt gatcgctgga gcaaaattcc gtggtgaatt tgaagaaaga ctaaaagcag
    30961 tcttgaaaga agtcaaaaaa agtgatggac gtatcctctt gttcatcgat gaaatccaca
    31021 atatcgtagg ggcaggaaaa acagaaggaa gtatggatgc cggaaatctg ttgaaaccaa
    31081 tgcttgctcg cggtgaatta catttgatcg gtgccacaac tttagatgag taccgtcaat
    31141 atatggaaaa agacaaagcg ttggaacgtc gctttcaaaa ggtattagtc aaagaaccaa
    31201 cagtggaaga tacgatcagt attctgcgtg gattaaaaga acgttttgag atccaccatg
    31261 gtgttaacat ccatgacaac gcattagtag cagcagctac tttatctgac cgttatatta
    31321 ctgatcggtt cttaccggac aaagcaatcg atttgatcga tgaagccagt gcaacgattc
    31381 gggtagaaat gaactctatg ccaacggaat tagatcaagt tactagacgt ttgatgcagt
    31441 tggaaatcga agaagctgca ctgaaaaaag aatcagatga tgcaagtaaa aaacgcttga
    31501 aaaatttgca agaagaatta gctgaacttc gtgaagaagc aaatgcgatg aagatgcagt
    31561 gggaaacaga aaaagaagaa gtcaattctg tttcagcaaa acgtgctgaa atcgataaag
    31621 caaaacacga attagaagat gcagaaaata actatgattt agaacgcgct gctgtattgc
    31681 gtcatggtac gatacctcaa ttagaaaaag aattgaagga attagaagct aaagcaaaag
    31741 acagcgagat taagatggtt caagagtccg ttaccgaaaa tgagattgct caagtcgttg
    31801 gcagattaac gggtatcccc gtaacgaaac ttgtagaagg tgaacgagaa aaactaatta
    31861 aattgaatga aacacttcat aaacgagtga ttggtcaaga tgaagcagtt gatgcggtca
    31921 gtgacgcggt aattcgttca cgggctggat tgcaagaccc aaatcgtcct ctaggttctt
    31981 tccttttcct aggaccaact ggtgtcggaa aaaccgaatt agcgaaagcg ttagctgaga
    32041 acttgtttga ctcagaagat catatggtac ggatcgatat gagtgaatat atggaaaaac
    32101 atgctgtgtc tcgtctagtc ggagctcctc caggctatgt aggttacgaa gaaggtggtc
    32161 aattaacgga agctgtcaga cgaaatcctt atacaatcgt cttgttggat gaaatcgaaa
    32221 aagcgcatcc cgatgtcttc aatatcttgt tacaagtcct agatgacgga cgcttgactg
    32281 attcaaaagg gcgagtagta gatttcaaaa atacggttct gatcatgacc agcaatatcg
    32341 gttcacagtt actgctggaa ggcgtgactg ctgatggaac gattccagaa gcagtggctg
    32401 aacaagtcaa cacgctatta cgtggaaact tcaaaccaga attcttgaac cgaatcgacg
    32461 acacgatttt atttacacca ttgagcctag acaacgtgaa aggaatcgtt gacaaaatgg
    32521 tggcgcaatt ggcacaacgt ctggaacatc aagaaatcct gctgacaatc agtgatgaag
    32581 ccaaaacgtg gattgctgaa aatgcttatg aaccagcata tggtgcaaga ccattgaaac
    32641 gatttatcac taaggaagta gaaacaccac tagctaaaga aatcgttgca ggacatgtta
    32701 tgcctaaatc aaaagtaacg attactttac ttgatggaca acttcatttc aaaacagaag
    32761 agctagaaga aatcgtctaa tcttccattg agactataaa agaaaaaagg ggtctgacac
    32821 aactagtgtc agacctcctt ttttcaaata aacagtgttc cagaagtagt ttcttcgaaa
    32881 aataagccga aatttcttga agctgcccgc ttctgtcaca acctctttta ttaggtattt
    32941 ttcacttttt ctaatttata actttcaaag taacgctcat cttttttact ttgagaccat
    33001 gcaaacaatc ccattaaggc agcacctatc gtatttgtca gcaagtcgcc catcgtatcc
    33061 atcaatgctg ctcgtccgac aaacagtgtg ccatcagaag cagcaaaacg ttgaagattc
    33121 atgcctaaga actggtcgca taagaattcc cagaactccc aaaacacgcc gcaaagtcca
    33181 gcaaacgcaa agccgaataa gaggaacaac caaggactgg tttttgatat ctcagcatct
    33241 ttcatcaagt aaccaatcaa tccatagcca agagctgtca ggaccattgg actcaccgca
    33301 tgtaagattt tgtcccaaaa agagatgata ctgatcaaat gcatccctgt gcctaaaaag
    33361 acagagatga acaagaaaaa ccagtaaaac aaaacgattg ctgctggtat tttaagtttg
    33421 aaaactttca aaatgacttg tggcatgaaa atcaatgcaa tccctaataa agattccacg
    33481 ataaatgtga ttccttgaga agtcgaatat ttttgtgtga taaattcata aaaattatag
    33541 cagacaacga atacaccaaa agcaagtaaa gctatttgca cctttttgat ttctttaatc
    33601 actgaaagtc cctccatcta aaaatctttt tacttctgaa agcaactcaa tttctgaaga
    33661 aaccactttt ccgttcaatt tgatcaaacc tattgtatat aagttcaggt agtgaaattg
    33721 attttcagct gtttcttgta gtgcagcgat ttttttcggg tgggttccgc cttgctgtcg
    33781 agtatcagta tataagccga tcactgggat gcctttcgca taagccacac cgatttccga
    33841 tgctaccccg gcatcgatcg tcagcccatc tagtaaagca atcattaaat cactagccaa
    33901 cactttttct gtgtcagcaa gagcaatcat tcgactgtct gcataagcag ttttgtcatt
    33961 gattgcttca ttttcttgag gaagatagat cgaaagctca gaagagagct ctctgatttc
    34021 tttaactaac tgttggttat ataacaaatc acttttagca aacattggtg cggcaaaata
    34081 aattttcatc taaacatcat cctttttatc aaaaataatc gctaaagtaa gcttccatgt
    34141 ttggaatgat acgctctagt gacttcagtg tttcttcatc tgtttctaac cgttcgattc
    34201 ttgccaaata agaagcacgg cgataattca tcatcaagca agtcaatgtt tggatatcca
    34261 gtcgaacgga ttttcctata ggttcattta agacacggac ttgtccctgt tcatcccatg
    34321 ttaaagcgaa gacaccatta ttccaaggag cgacaggatc ttcaatgatg aaatgaaaag
    34381 catcagctgt tccaacaaac ggaaaccgtt gaaggaattc ttttacatca acgatccgag
    34441 ccataaaata tggttcgatc tgctctttga tctgactatc ttcaatcaaa aatgctaaag
    34501 gctcattttt ataaatatct ccatgtaccc agtagatcat ggaaaaatgt gcggaaataa
    34561 agttccataa gccatttcga gcttcttgat caagatagaa catttctttt acgtgaaata
    34621 tttcttcagc tacccagtag aacagaacac ctcttggttc atggttgcta tcgtagtaga
    34681 cagcggctgt gcgctcatct tcattttcga aacgccaata ctcttcccaa tgaaaatcac
    34741 tgcggaataa agcaccatgg ttttgttggg caaatttgtc ataaacggaa aatacgtctg
    34801 gatgatcaac tggtaatcgc tcaaccatac cacttactgg gatttgttta ggtagctgtg
    34861 tatctctgat tttaaaggaa agtttatcag acatgatttc ccatccttta cgccgatagt
    34921 aggggatact gtaaggatac aaataagaga tccattgctt attcttgcgc atattatcca
    34981 atgcaacgat aattagatct tgcatcaatc catggttagc atattctgga taagttccaa
    35041 ctccagtcac accacccatt ttataacgtg caccgtgaat attgacttca caaggataga
    35101 tagcgatttg agagatcagt ttattttcgt ggaaccatcc gaacactttc gatacttcca
    35161 aaatcggttt tttggaacgg ataaaagctc gtttattctc aaacccgctt tcctcgatgt
    35221 ctgcttcagt cacttggaac acataggaaa gcaattcatt gaattgatcg atatgttctt
    35281 gagtgaccgg ttttaattca agattttctc taaaatcttt ttgatccatt ttttcatctc
    35341 catttattag cttgataaca gtatagcaaa attctacaaa aaaaacttct atagctgact
    35401 aattaaaaac tctttaaatt actgcttttc gttggtataa tggaaagtgc tgattatatg
    35461 aaaagaggag acgctatgga tataaagaaa atgaaagaac gccaagagca gattcgtaat
    35521 ttttcgatca tcgctcatat cgaccatggg aaatctacat tggccgatcg tattttagaa
    35581 atgacgcaca ctgtgacgtc tcgcgaaatg caagatcagc tgttagactc gatggatttg
    35641 gaacgtgaac gtggaatcac gattaaatta aatgctgtag aactcaatta cacagcgaaa
    35701 aatggagaaa catatatctt tcacttgatt gacaccccag ggcacgtcga cttcacctat
    35761 gaagtctctc gaagccttgc tgcctgtgag ggtgccgttt tagtggtcga tgcagcacaa
    35821 ggaatcgaag cacaaacatt ggccaatgtt tatttagcgt tagacaatga tttggagatc
    35881 ctgccagtca tcaataaaat cgacctaccc gcagcagatc ccgaacgtgt ccgtcaagaa
    35941 atcgaagacg taatcggaat cgatgctagt gaagctgtat tagccagtgc caaatcaggg
    36001 attgggattg aagatattct cgagcagatc gtggaatatg ttcctgcacc aagtggagac
    36061 ttagatgcac cgctaaaagc tttgatcttt gactctattt atgatagtta ccgcggtgtt
    36121 gttctaaatg tccggatcac ggacggtatg gtcaaacccg gagacaaaat caaactgatg
    36181 agtaatggca aaacatttga tgttacagag gtcggggtct tctcgccaaa agcagttgct
    36241 agagactttt tgatggtcgg tgatgtcggt tatatcacag caagtatcaa aactgtccaa
    36301 gatacacgag taggggatac agtaacgtta gcagacaatc ctgccgctga agctttacca
    36361 ggttaccgaa aaatgaatcc gatggtttat tgtggtcttt atccaattga tacttctcgt
    36421 tacaacgatt tgcgggaagc tttagaaaaa ctgcaattga atgatgctgc tttacaattc
    36481 gaaccagaaa cctctcaagc attaggtttt gggttccgct gtggattcct cggacttctt
    36541 catatggatg tcgtccaaga acgcttggaa cgggaattca atctagaatt gatcacgact
    36601 gcaccatccg ttatttacca tgttaataaa acggatggta cgactgctac agtagataac
    36661 ccggcagatt ttcctgaacc tgtaacgatt caggatgtag aagaaccatt cgtcaaagca
    36721 cagatcatgg tcccaaatga ttttgtcggt gcagtaatgg aactttctca acgaaaacgg
    36781 ggagaattca ttacgatgga ttatttagat gattaccgag taaatgtcgt ctataatatt
    36841 ccgctttctg aaattgtctt tgactttttc gacaaattga aatcaagcac gaaaggctat
    36901 gcctcattgg attatgaaat gtctggttat caaaaaagca agttagtgaa gatggacatc
    36961 ttgctgaatg gagaaaaagt cgatgcatta agctttatcg ttcaccgaga ctttgcctat
    37021 gaacgtggaa aagcaatcgt tgaaaaactg aaaaaactaa tcccacgcca acaatttgag
    37081 gtgccaatcc aagcagctat tggacaaaaa atcgttgccc gttcagacat caaagccttg
    37141 cgtaaaaacg tcttggctaa atgttatggt ggagatgttt ctcgtaaacg taaactctta
    37201 gagaaacaaa aagaagggaa gaagcggatg aaacaaatcg gctccgtcga agttccgcaa
    37261 gaagccttca tggccgttct gaaaatggat gagcaagata gtgtgaaata acttataatc
    37321 aatcgaaaaa cctattaaat aaaccttttt gagtagatgc aacactgagg attatctgta
    37381 taaaagattt taaactgtca tttggttatc acggcgatac taaaattaac aaaattggaa
    37441 tatttttctt gaagattttt agctgtcagt atatgatgaa agcatctcat aggaggtgct
    37501 tttttcatgg ttgataattc aagtggaagg gttcttaaat ctctaagaaa agagaaaaaa
    37561 ctatctcaaa aaaagttagc tgatttagca ggtatttcac aaagtacttt agttaaatat
    37621 gaaaaagggt caagaaaaat ccctaaagac gtagataata ctctaagcaa gattctgaat
    37681 atagaaactc taataaaaga tgaggaagat aagattgaga ttctcatcgg taaactaatt
    37741 gcatacagag atatgaataa gttacttaac aaagagttag ctgataatat aggaattagt
    37801 gaagtattac tcagttatgt gttaaataga aagagaaatc cgtcaaaaga aatgcaaaaa
    37861 aaaatcgata tttttctatt aagtaatgaa aaagaaattt tgaaggagat taatcgtgat
    37921 agtgagatat ttagtttatc aaaagacgat aaaattgtta tgggaaaaag aatacgagaa
    37981 gtccgaaaga accgggaaga gacgcttgaa aaatttggta aaaactttac catctataca
    38041 ggcaaaaatg ttataagtag atgggaaaaa ggtattaata ttccagatat tgaaaaacta
    38101 atgaatattg cctatcttgg taaggtcact gttccttacc ttatgtacgg agaagattat
    38161 aagaatatac ttccaaaaga tgaaagagtt agcgatttta aaaagataaa ttcttttagt
    38221 atgggattaa ggatgaggaa aattaggaaa gattattatc tagaaaggga ggagtttgga
    38281 aagctttttt ctccttcaat ttcaaaatgg tccatagata ggtatgagaa tggtagagat
    38341 atacccaata ctaatcgaat tatccaatat gcttatatag gaaatctttc tttagaattt
    38401 ttgatttacg ggatataaaa atagtttacg tcgatactta ttaagttatc gacgtttttt
    38461 attatagaaa aaatttataa aaggaggttt cttgatatga taagaaacaa aaagggtttg
    38521 ttgaaagttg ctttactggc agcttttttc taagtaactt tttgacaagc tcaatggcaa
    38581 cacaagcgga agaagtaata caagaactaa ctgttatgaa taacagctag ataaaatggg
    38641 ctatgtatgt tatccaacaa tttagtaatc actagaagcc tagcgaaagt tcgcttgata
    38701 agttatagat gagtattgat ttgtagtgtt tccaaatcaa aagggtacag agccacatga
    38761 aatatgttgt cctctgcagc gtcaggatgg gaatccatac catggagatt cggagatctg
    38821 tgagggaata cttacgtggt taatatgtca gttgtgttgg acgtagtaat ggtcatagtg
    38881 ggtagattga ctgaattctt atatgagaaa atgaaaccaa caagaagata gggttattta
    38941 tacagaattg gggatctttt ctggaaaagt aatcggataa tgcgagattc gtacggtctt
    39001 ttttaaattt ctctaaaaaa aacggcatcg aatgggttgg gtgattgata agcaatgaat
    39061 catagactga tatagaataa aaaatgattc tatttatctt tttacatcta tcgttttttc
    39121 aagtagccgc aaattatatc agcattcaac aatttttgta tacaagttct agtaaaagga
    39181 tctgaagaaa aagttggttg ttgtgaagat
//
LOCUS       DAYYEF010000022        38390 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000022 DAYYEF010000000
VERSION     DAYYEF010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.022"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1778)
                     /locus_tag="ACHA1B_001312"
     CDS             complement(<1..1778)
                     /locus_tag="ACHA1B_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFM8702087.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPA"
     gene            complement(1765..1983)
                     /locus_tag="ACHA1B_001313"
     CDS             complement(1765..1983)
                     /locus_tag="ACHA1B_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702088.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            complement(2059..3111)
                     /locus_tag="ACHA1B_001314"
     CDS             complement(2059..3111)
                     /locus_tag="ACHA1B_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFM8702089.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            complement(3264..3590)
                     /locus_tag="ACHA1B_001315"
     CDS             complement(3264..3590)
                     /locus_tag="ACHA1B_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702090.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            complement(3602..3802)
                     /locus_tag="ACHA1B_001316"
     CDS             complement(3602..3802)
                     /locus_tag="ACHA1B_001316"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702091.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            3925..4527
                     /locus_tag="ACHA1B_001317"
     CDS             3925..4527
                     /locus_tag="ACHA1B_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8702092.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            4582..5748
                     /locus_tag="ACHA1B_001318"
     CDS             4582..5748
                     /locus_tag="ACHA1B_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8702093.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            6165..9392
                     /gene="fss3"
                     /locus_tag="ACHA1B_001319"
     CDS             6165..9392
                     /gene="fss3"
                     /locus_tag="ACHA1B_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HFM8702094.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            9504..9818
                     /locus_tag="ACHA1B_001320"
     CDS             9504..9818
                     /locus_tag="ACHA1B_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFM8702095.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            9831..10205
                     /locus_tag="ACHA1B_001321"
     CDS             9831..10205
                     /locus_tag="ACHA1B_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HFM8702096.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            10215..10559
                     /locus_tag="ACHA1B_001322"
     CDS             10215..10559
                     /locus_tag="ACHA1B_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HFM8702097.1"
                     /translation="MEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQGLL
                     EVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFLKQL
                     VETKQLPVVVND"
     gene            10628..11644
                     /locus_tag="ACHA1B_001323"
     CDS             10628..11644
                     /locus_tag="ACHA1B_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsK/SpoIIIE domain-containing protein"
                     /protein_id="HFM8702098.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            12238..14112
                     /gene="ltrA"
                     /locus_tag="ACHA1B_001324"
     CDS             12238..14112
                     /gene="ltrA"
                     /locus_tag="ACHA1B_001324"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFM8702099.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            14214..14594
                     /locus_tag="ACHA1B_001325"
                     /pseudo
     CDS             14214..14594
                     /locus_tag="ACHA1B_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            14639..15781
                     /gene="dcm"
                     /locus_tag="ACHA1B_001326"
     CDS             14639..15781
                     /gene="dcm"
                     /locus_tag="ACHA1B_001326"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003886 - DNA
                     (cytosine-5-)-methyltransferase activity [Evidence IEA];
                     GO_process: GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HFM8702100.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            15771..16060
                     /locus_tag="ACHA1B_001327"
                     /pseudo
     CDS             15771..16060
                     /locus_tag="ACHA1B_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16316..17500
                     /gene="mobT"
                     /locus_tag="ACHA1B_001328"
     CDS             16316..17500
                     /gene="mobT"
                     /locus_tag="ACHA1B_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MobT family relaxase"
                     /protein_id="HFM8702101.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            17497..17610
                     /locus_tag="ACHA1B_001329"
     CDS             17497..17610
                     /locus_tag="ACHA1B_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HFM8702102.1"
                     /translation="MKRGILMEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
     gene            18380..20290
                     /gene="ltrA"
                     /locus_tag="ACHA1B_001330"
     CDS             18380..20290
                     /gene="ltrA"
                     /locus_tag="ACHA1B_001330"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFM8702103.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            20394..20618
                     /locus_tag="ACHA1B_001331"
     CDS             20394..20618
                     /locus_tag="ACHA1B_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702104.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            20631..21134
                     /locus_tag="ACHA1B_001332"
     CDS             20631..21134
                     /locus_tag="ACHA1B_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HFM8702105.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            21261..22298
                     /locus_tag="ACHA1B_001333"
     CDS             21261..22298
                     /locus_tag="ACHA1B_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic GMP-AMP synthase DncV-like
                     nucleotidyltransferase"
                     /protein_id="HFM8702106.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            22313..24010
                     /locus_tag="ACHA1B_001334"
     CDS             22313..24010
                     /locus_tag="ACHA1B_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="E2/UBC family protein"
                     /protein_id="HFM8702107.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            24003..24464
                     /locus_tag="ACHA1B_001335"
     CDS             24003..24464
                     /locus_tag="ACHA1B_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HFM8702108.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            24477..25337
                     /locus_tag="ACHA1B_001336"
     CDS             24477..25337
                     /locus_tag="ACHA1B_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702109.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            25375..25764
                     /locus_tag="ACHA1B_001337"
     CDS             25375..25764
                     /locus_tag="ACHA1B_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFM8702110.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            25751..28198
                     /locus_tag="ACHA1B_001338"
     CDS             25751..28198
                     /locus_tag="ACHA1B_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM8702111.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSMI
                     GDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            28203..30311
                     /locus_tag="ACHA1B_001339"
     CDS             28203..30311
                     /locus_tag="ACHA1B_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFM8702112.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            30308..31312
                     /locus_tag="ACHA1B_001340"
     CDS             30308..31312
                     /locus_tag="ACHA1B_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HFM8702113.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            31331..32242
                     /locus_tag="ACHA1B_001341"
     CDS             31331..32242
                     /locus_tag="ACHA1B_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HFM8702114.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
     gene            32429..32716
                     /locus_tag="ACHA1B_001342"
                     /pseudo
     CDS             32429..32716
                     /locus_tag="ACHA1B_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(32904..33119)
                     /locus_tag="ACHA1B_001343"
     CDS             complement(32904..33119)
                     /locus_tag="ACHA1B_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702115.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(33378..33587)
                     /locus_tag="ACHA1B_001344"
                     /pseudo
     CDS             complement(33378..33587)
                     /locus_tag="ACHA1B_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
     gene            complement(33890..35329)
                     /locus_tag="ACHA1B_001345"
                     /pseudo
     CDS             complement(33890..35329)
                     /locus_tag="ACHA1B_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(35877..36548)
                     /locus_tag="ACHA1B_001346"
     CDS             complement(35877..36548)
                     /locus_tag="ACHA1B_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HFM8702116.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            complement(36897..38348)
                     /locus_tag="ACHA1B_001347"
     CDS             complement(36897..38348)
                     /locus_tag="ACHA1B_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFM8702117.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
BASE COUNT        12796 a         6502 c         7459 g        11633 t
ORIGIN      
        1 cttgcaggat tattattcga ttcagcatta tttttcattg cttcacgcat acgttcagaa
       61 ctagacataa ttctatcggc attttcaact ttagcaccat cttttctatc tgaaagacgt
      121 gttggcacgg aatcagcata ttttccagtt tcatcttctt tatttttagc taacataggt
      181 ttgctatttt tattaatagc ggacactgta ccatcatcta aaccttcttt aaacttattc
      241 ttggtatcat tagctatatc acgcatactc ttaaatggtt ttgttgctct ttcactagcc
      301 attgtagctc catctgaagc taaaccggat aatccacgtt catgggcata tcccaaagct
      361 cttccagttt tgccagcttt ttttgataga gtttcgccga aattcttttc tggttttcga
      421 tcttctcctt ctccgcttcc tttagcacga ttaaatccat ttgatccttt tctaaacagc
      481 attgcgccca ttccaaaagc agaagcaagt tgcccatagc cttctttgag tccaatatca
      541 acaccaaagt atctcatgac tgttccactg cctttgatta aaacaaaaac ggcacagata
      601 taagcaattg tttttataaa aatatttgtt gagatacctt gtcctgagtt cagaaaattg
      661 ataaacatag caaacattga taacccaaat ccttgaaacc caacagttaa gtaacattgt
      721 agaatatctg atagaacaac ttttgaacgc tgtcctgtct caatatctgt tgcaaaaaca
      781 agaacaccta acacacgttt aaatgcaagt tctagtattg ctgtaatgat cacaaacgcg
      841 ctgaacacat aggcgattgc taacgctgtc aacccaattg aaatccccca tagatttgct
      901 tggtatcggt aatagcctga tttcaagcta tcagaaaatg ttgataagaa gttgtcagaa
      961 aactttgtag caacaaattc attattagaa ttttcaacta attcataacg aagattgtcc
     1021 gcaattggat tttctttttc caatttatca atcactttat ccgttaacac ttgtgtgaga
     1081 tccgtctgtt gaaaattttt tcgtgttaaa ttatttcgat cctccgtttt atcaatgctt
     1141 gagtactgat ctgttttatt aatatatgct aaatctgtta ctccttgttt tatcaatgac
     1201 caagcgactc cgtcatctga atttgtaatc gtagtagagt ccttataaaa tgttttagca
     1261 aattgaatac cactagaaat catggttggc attaaaagta ttaatgctat agacatcact
     1321 acgttcattc caaccgattt taaatccact gttccttttc cagtaatcat tttgtaacca
     1381 acaaacatca atgaaaggat cattaatcca atgacaattg tatttacggc tgattgataa
     1441 acattattta gccctgtact ttcaatgaaa ttgaacaaat ccagcacatc tggaatcata
     1501 ttttgaatcg aatctgtcac agtaaacatg ccttttacca cagcccatcc gagccaaatc
     1561 ccgaactgac taaggaaatc tccattgtac ttttttaggt aaggtctata aagagaatta
     1621 ttcaaaaact ctgtttgact ttttgtgtca tcaaaccaat tgaaaatact cgcatgagca
     1681 atattacttg taaaaataat catagctatc agaacaagaa aattaacaac caaccaattt
     1741 atttttttat tggcaatctt tttttcaatt attttcatcg ttacctccct tagcccattt
     1801 tctgaggctc tcagagagct tctgagccat tttttgatta attatgacat gagttacaca
     1861 attatcattt tcagctctta aatcgagaac tatagtgttg aagcaaatag tctcgattaa
     1921 ttcgagacta tctgtatttt gatctagaca ccaaacttga tctattaaac gatttttaat
     1981 caaaataacc cctcctatat tcaaagttct caaatgaagt ggagataccc ctccatttca
     2041 tttgactcaa ttctattctt attgcttatc tattccttcg ctgatttgca attcaattag
     2101 ttctaacgct ttatttttta gagaagcaaa gatataatcg tctttttgtt tgatacgatg
     2161 atctgttttt gctcttcgta tcaagtcacg taaagtcatt gatagctgtt ctctaacatg
     2221 atctacaaaa tacttgttat tacaaatttc atagataatt ttcagttgaa ttttttgttc
     2281 tttttcagca gatctaatcg catatttgaa ttttttgtac cagttgtcga attgacgata
     2341 atcactattg ctagccagtt ttaagcaatt cacaatactt tctccccata tttgtttaag
     2401 aagattttct tcaataaatg tttcgatcaa ttcttcatct aatttattat ttttagttga
     2461 aagtgattca agaagatcat cattatgtga ttctttaata tctttactat ctttataaga
     2521 cttatataat tctagttcat tttttgaact atcagcaaaa ttgtttttgt ctcttgtttt
     2581 cattgatgtg tcgcatagtt caaattttga actatcaaca gaatattgat ttgttccata
     2641 gttcaaattt tgaactatca agtttttttg tctattttct tgatgggtta tcttattaat
     2701 tttataaaca tcatctttgc acagaacagg ctttaacaaa taataaaaat ttgggaacat
     2761 ttgcatttta cttttattga agccattttt tcttttcaca agaagtttaa ctttttgaag
     2821 ttcatctagt gctgataaga ttgtattttt tgacattccc gaaatttcta cgagattttt
     2881 gatttcaaat atcaaaaaaa ttttttgatt ctcatcatac aagttatttt tcaatgaaag
     2941 tctatttcta tcttttagta acatataaac taacttagaa cttagtttca ttttcttata
     3001 tttttcattt acgtttaaaa aaataggata ttgatagtat aattctgcat atatatcaga
     3061 attagaatag ccttgctttt caactaagct ttcaacttct ttttcattca ttgtcacacc
     3121 tgcttctgat tttatttgct ataatagatt caaataaagt tttctcagaa ctttattatt
     3181 gagtgttccc ccgatctgca aactgacggg aacactcttt ttaatttttt ctacttcatc
     3241 aaatttaaaa aacgaggtgt tttttaaatt tgatgactca atatccattt tttgcattct
     3301 tcttttgaaa acaactccat tttttctaat aaaataactg gcaatcccat tcttttaaat
     3361 ttcaaaaaag ttgtatatga tacattcaaa tatttagcca tctcttttcc ttttagaaat
     3421 ggtctttcta atccggtatc aattcttgct tgatcaatag cctcttttgt catttcaaaa
     3481 acataatttt tcaattgatt cgtttgttgt ttatctaaca ttactgtaat tcctgcatcc
     3541 attatttttc tcctctcatt ttctatttct tcaatcagcc aactcgccaa gttgtattta
     3601 tttagatttt caaatcatta agtaaccaat ttaccaactt ttgataagta gatgctctaa
     3661 tactttcttt gctcccattt tcgattttga catatgtttt ccgatttata cctatcaatt
     3721 ttgctgcatc gtttttagta agtataagat cggctctatg tcttcttaag cttctaatga
     3781 attgatcatt aagagttatc attcagcgcc tcctttcaaa ttattcactt tgtggttttt
     3841 atcttaataa gcacatttta aaccacaaaa cgagtaatat caattaaaat attactcaat
     3901 ttgtggtttt catgctataa tagtttggaa tttactatag ggggcgttac tttgaataga
     3961 ataaaatttt atattgattc cagtaaaaag accattaaac aaattagtac agaaactggt
     4021 attaactata caactcttac gaactattac cgtggtgagc gaaatcctag aaatactgaa
     4081 acatggaata tccttgctga ttatttccat gttcctgtaa gttatttgat gggattagac
     4141 gaaacaaatt ccatagaaca acctaatctt gatagaataa aaactgctcg tttagaaaaa
     4201 aaggacaaaa tagtcaagaa tattgccagt cttgactcag attattttac tgaattatct
     4261 aatctatact tttccatgac ttctttactt gaagtcaaac ttcaagaaga tgactccgac
     4321 tttctttttt taaaaagtat tctagaggac tcctttgaat acacgattct atttgccaaa
     4381 caaaagaagt ttattaataa agctttaaac ttaaatatcg atgaaagaaa agagttagaa
     4441 tctgagttat ttggcaactt aacccaagta caggttaaca atctaaaaag agagataaca
     4501 gctcgattaa tatcaaaact tcaataaaac taattattca atcagccaac tcgccaagtt
     4561 atcagattgg agagattagt tatgtcaata caaaagtaca caacaaaaag cggtgcacga
     4621 tatagtgtcc gcttgtatgt tcgtaaagat gaaaatggaa agcaagaata ctatgtaaaa
     4681 aaagggttta aaactgaaaa agaagccaag ttacacgaag caagaaaaaa ggtcgagatt
     4741 gaagataccg gctatcataa gccttctaat gacttgttta taacagtgta tgaagaatgg
     4801 ttgccttctt ataggaatcg tgtacaagaa acgacatatc aacgtacaaa agaccttttc
     4861 cgcttgcata tactaccaaa attcgggaat aagtccattt ctaagattac tcctgttcac
     4921 tgtcagaatg cagtcaatga atgggcttta aaattcaaga atatcaaaca gcttaagtct
     4981 tacagctctc aaatatttga gtatgccatt tttgcagagc tattacaccg aaatcctatg
     5041 gcaaatacaa atctaccaaa gcgggaaaag aaagaaaatg aaaattactt ttcattagaa
     5101 gaactaaaag ctttttggga tattctcaat aaagaagagc ctttaaaaca tattttaatc
     5161 ttccagcttt tgattactac tggtatacgt aaaggagagc tagctgctct tcattggtct
     5221 gacatttatt ttgaagaaca gctaatgtat gttagaaaga gctatgcaac tattcgaaat
     5281 gaagagaaga atgcaagaag aaaaactgtc aggattcaaa aaaatacaaa aaatatatct
     5341 tccgaacgaa tattaccaat tgatgcacaa actattgaaa tgttaaaaat ctggaaaaaa
     5401 gaacaagctc gagagctttt gcagtttggc ataaatacaa atacaaaaaa tcaacttatc
     5461 tttacctatg taaatgcaga cggtgacatt aatcaacctt tgcatgcgga ctattcaaat
     5521 aatatattga aacgtttaga gaagaaatat aaatttaagc acgttactat tcatggattc
     5581 cggcacactc acgctactct tctactagaa ggtggagcaa gtatcaaaga aacacaagat
     5641 cgattgggtc ataaaaatgc tgaaactacc cttaacactt attctcatgt tactgaaaaa
     5701 gctcaacgaa atgcgttaga aaaattcatt gcttacactg gtttataata ttgtcattac
     5761 ctttctcatt accagaacga aaaaaagaca ccttctcgca atgagaaagt gtctgaaatc
     5821 gttggtataa caacgattaa cgttttgaaa actgtgaagc tttacgtgct ttcttaagac
     5881 ctggtttttt cttcgtatca ttgaataagt ttgaaaagcc ttgatttata aaggtttttc
     5941 cgtaaatata ttttgttata tttgattaaa tttgaaatgt ttgtgttcta aaatgtgttc
     6001 taatttaaag gcagtatatt tcgtatttta tattaaattt ttaggctcat tcattctcaa
     6061 atccattcta tttagtcaat aaatatttta aaaagacttt ataaacaaag atgttcaagc
     6121 gagcatctta tttttttgtg cctaatttga aaggagaaca tttcatgtat aaaaaacaaa
     6181 aaaagaaatt atgtgtatta actattttga gtttggctgt tcaatcaatt gtaggagcaa
     6241 ttgctcctac gattgctttt gctgatgaaa ttacccatcc acaaacggta accgtagaac
     6301 tagatttagc acatcaatat gctgttgaag gaacttttag tgatggtcgt ccaatgtcag
     6361 aagtcactgt tccgcattat gcagtgtaca acggcgttaa acaagatatt ttctgtgttg
     6421 aaccaggagt cccgatttac aatgagttca ctcctggata tgagaagaac ccgttaccag
     6481 atatgtccga taaagccaaa ttagtttccg ttttatggaa aaaagtaggt acagatgcag
     6541 atactcatat tgtggcacag aagatgatct ggcaagaagt taatgggtat acccttcact
     6601 caataaaacg atcagatggt agtgccgtaa atatcgcagc cattgaggca aaaatcaatc
     6661 aagccattgc cgattatcag aagaaaccaa gcttccataa tagtacggct aaaacagtat
     6721 tagggcaatc gactactgtg acggatacga ataatctgaa tttgtcagag ttcgatgagg
     6781 ttgtggaaaa taccgcaaac attgattatc gtgtgaatgg caatcagttg ataatcagcc
     6841 caaatgccaa ttcaaaagaa agtggtgtgt tgacgcttaa gaaatctgct ggtaccggaa
     6901 cacctgtcgc ctataaaaag gctggccaac agactttaat ggccggggcg atcgataagc
     6961 cgaacactta tacggtcaaa attgatgtgg aaatggaggg ttctttgaag attaaaaaag
     7021 ttgataaaga atcgggtgat attataccag gaacggtttt ccatttagac tttggaaaaa
     7081 ctttacccgc aaaagacgtg accaccgata aagaaggcat tgcgacctta gatgagattc
     7141 ctcatggtac aaaggtaacc attactgaaa aatcggtgcc ggcgccttat acgattgata
     7201 ccacacccat gactgccaca attaaagcag gtgaaaccat ttcagtgact tcaaaaaata
     7261 cgcgagaaaa aggtcaaatt attctggata aaaccggaat tgaaacaggg agtgatcttt
     7321 ggaacgataa ttactcttta gcgggcaata cgtttgccat tcgcaaggat agcccaactg
     7381 gtgaaatcgt ccaagaaatg accacggatg aaaaaggtca tgcagaaaca ccaaaagaga
     7441 ttgccaatgc gttggaattg ggaacctact atgtgactga aaccaaggct agtcatggct
     7501 ttgtgaatac tttcaaacca gtaaaagtcg aattgaatta tgtcaatcaa acagtggctc
     7561 ttgttaccag taacgtaaaa gggcaaaacc aagaaattac tggtgaaacc actttgacaa
     7621 aagaagacaa agataccggt catgaaactc aagggaaagc tgagtttaaa agagctgaat
     7681 acaccttgtt tactgttaag gatggaaaag cggtcaaatg gaccgagaac tttaaaccag
     7741 aattgttgaa gggaacgaaa gcttctgatg aaaccgtaac tttgacttta gatgaaaaga
     7801 atcaagttgc cgttaaacac ttagcgatta atgagtatta ctggcaagaa accaaagcgc
     7861 ctgaaggata taccttggat gaaacaaagt atcctgtatc catcaaaaag gtggatgata
     7921 gcgaaaaaaa tgctgtgatt actcgagatg ttgcggcaaa agaacaagtg attcgctttg
     7981 gctttgattt ctttaaattt gctggatcaa ctactggcac tgccgaaact ggcttcaatg
     8041 atctaacctt taaagtgtcg ccattggaag gaaccaatga aatcaccggt gccgaagatg
     8101 aagcgaccac agcttataac gagcaattag ggtttgatgg ttatggcaag tttgaaaatc
     8161 ttccttatgg ggattattta cttgaagaag tagaagcccc agaaggtttt caaaagatta
     8221 cgccattaga aatccgttct acttttaaag aaaataaaga ggattatacc aagagtgatt
     8281 atatctttac tattaccgaa aaagggcaaa agcaaccgat taaaacggta acggtccctt
     8341 atgggaatct aaccaatgag aatttctcag tcagtttgaa ccgtttgatg ctttatgatt
     8401 tgcctgagga agaagatagc ttaacttctc ttgcgacttg gaaagaagga gataaagaat
     8461 tgactactct tgattctacc gagctagtcg ataaattgag ctataatcta catgaaatca
     8521 aagaagactg gtatatcgta gctcaagcca tcgatgtaga tgctacaaaa gctgcccaag
     8581 aaaaagataa aaaagccaaa ccggtggcga ttgcggaaac aaccgcaact ttagcgaata
     8641 aagagaaaac aggaacttgg gagattctgc ataaattaac tgtcgaacaa gttttagaca
     8701 agaccattgt cttattcaac tatgtgtatg aaagcaaaga agcctatgaa gctggtgatg
     8761 agccggtagc gaaggatgct agcttgaaca atcaagcgca aactgttaat tgtatggtgg
     8821 aacgtcatgt ttccatccaa accaaagcgc acttagaaga aggttctcag acctttactc
     8881 atggtgacgt ggtagatatg tttgatgatg tatccattac ccatgatgta ctagatggct
     8941 caaaagaagc ttttgaaaca attctgtacg ctttatttcc agatggtaca agtaaagaaa
     9001 tttggaaatc tggcaagatt gattacgaag tgaatgacaa agaatttacc aaaaccgtac
     9061 ttgcggaaaa agtggataca agtaaatatc cagaaggtac aagttttacc ttcaaagaaa
     9121 ttaactatga caaagatggg aatatcaatg gaaaacacaa tgaagatttg aaagaaaaat
     9181 ctcaaacttt aacgcccaaa aaagttccga caacaccaag tacaccagaa caatctgaaa
     9241 tgccaactgt tccaagtggc tctcaagaat ctagtcctac agtgaaggca ttccctcaaa
     9301 ccggggagaa aacttccaat gtgctactgt tcattggctt tagcttgatc tttgcgacgg
     9361 ctggctatta tttttggaat cgtcggaact aaggtgataa gatgaaacat gtaaatagta
     9421 gaaaacaata cgcgcgaccg cctcctaaaa aagtggtcgc gctatttttg tattcaaaac
     9481 taacaatgaa aagaggaaaa aatatggaat tgaaatttgt tgtaccagat atggtcgaga
     9541 cgttcggaaa actaacatac ggtggtgaag gtgaagttct atcggaaggg tatggtcgaa
     9601 atactacaat tgttggtcga agttaccatc tgttttcaaa taaacaacgg gccgatgata
     9661 ttgaagtggt ggtagctgcg gaagccggcg aaaaggattt tgaccaagat caaccactaa
     9721 aagctgtaaa tccccactta attgccaaag gctatgaaat tgagaatcgt gggtttaccg
     9781 attacgtgtt gtatgttgat gatttagtga aagcatagga ggaaaagaag atgagattaa
     9841 cagaaggtat tgtcgtagat tcaggattaa cctttggcaa gttgcgtttt tccgcattac
     9901 gtcgagaagt acgcaagcaa aatgaggacg gaacggttag taacgaggta aaagaacgga
     9961 cctataattt gaaatcctcc gcgcaaggtc gaatgatcca agtcagtatt ccagcaaatg
    10021 tacccttacg cgagtttgct tatgatgcag aggtagagct ggtcaatcca atcgtggata
    10081 cggtcgccaa ttatgttttt cgggaaggaa ccaccgttaa ttggtttatc aaggcagatg
    10141 atttagtctt gaaacgacaa ctgaatcaag gaaaacctac gaaccaaaat gaaggaaaga
    10201 aataggtgaa gaatatggaa attaatgttg aacatatttt agattgtctc gatcaatttg
    10261 gcaaaggtga gctaacggag gaacaactca ctaacgcatt aacctatgat gaaaaaatgt
    10321 ttctgattat gcatcaaggg ttactggaag taggtaacga tgccaaagaa gactttgatg
    10381 tactggattg gttaggggaa gaagagtctt tctttatggt tgtcgaggta aatgaaagtt
    10441 tatgtcggca ggcagaatct gttttggaag aaatcgatgt ggagatgccg gatgccatcg
    10501 aaagattttt aaaacaatta gtggaaacga aacaacttcc cgtagtagta aatgactagc
    10561 ataacttttt gaaattgccc aatgaaatcc tattgggctt tttcgactgg aggtggaaac
    10621 catcaaaatg tacaaaggac atcgcatacg cgcaggagat caacacttga tttatcactt
    10681 tgttcttggc tggctaatct ttttgttcat tggttggatg agcgtctttt atttacaaga
    10741 acttagacaa tttgatattt ctaaggtatc attttccact agtgaaattg gctggtctat
    10801 gaaggatgta atctgcttgc taggaagtct cgctctttca ggaagcatga tgttacttta
    10861 tatacacttt tttcaggatc attggcgaag tctttggcat cgacaaaagt tagctcggat
    10921 gattctagaa aaccattggt atgaagtaaa gcagactcaa ggtgaaggtt ttttcaaaga
    10981 tttgaatagt agttggacca aagagagtat cagttacttc cccaaaattt attatcgaat
    11041 gaaagatggc ttactttcta ttcgcgttca aatttcactg ggaaaatatc aggatcagct
    11101 attgaagttg gaaaataagt tagaaagcgg actgtattgt gagttagtag aaaaagaact
    11161 caaagactcc tatgtggaat acaccttgtt atacgatatg attgccaatc gaattgggat
    11221 agaagaaata gtggcagaaa atggggcgtt gcgattgatg aaaaatcaag tatgggcgta
    11281 tgattccttg ccgcatatgt taattgctgg cggcacaggt ggtgggaaga cctatttctt
    11341 actcaccatt attcaagcac tattgaagtc agatgcagaa ttgtttatcc tcgatcccaa
    11401 aaatgcggac ctcgccgatt taggtacgat aatgcctcac gtatactccc aaaaagaaga
    11461 aatttctgaa tgtgtggaag atttttacga acgcatgata gctcgtagta ggtcaatgaa
    11521 agaaatgccc aactacaaaa caggagagaa ttatgcgtat ctcggacttc cgcccaactt
    11581 tttaatcttt gatgaatacg tggcttatat gggtgcgaat cgttttccta caagcatcga
    11641 atagatgtga aatggaagcc tattgagatt atcaatagtg acaactaatg ttttgagaga
    11701 tggaatgaaa gccttcaagt tgagctgaaa catccccgct aatactccta catgctctaa
    11761 tcaatgaagt agattggttt tggtatgaag ctaggtgaag tcgtctgaaa tctgcctaag
    11821 tgcttgagca taaggctgac tatagggcgg gcggctgaaa aagataacta tggtaagaat
    11881 gtctgaaaat gactgacgaa tctgcgaatg tacgggtcta aaaggctgat cttattgaaa
    11941 gataggaaca tacggacgta tggtgagata ccgacaagta aggttccatg atatgaaaat
    12001 cgggatagct aacgaagaag ctataatttc acaggctcat agtagatacc taaggttata
    12061 catgatagct aaaaacattg gaacgatgta agcagaaaac tatcaattaa atgactactt
    12121 ctagataggt gcatataagt aataacgaaa ttgctttgtt tctgtgaaag taagggcaca
    12181 gtaccgatga agcgtctaac aaatgtggag ggatagccct aagtctattt aataacaatg
    12241 aatgttgaaa cagatgaagt tcaaggatct ggtaagaacg tgggaaaatc cgttatggag
    12301 gtgccacgct tgaacacaaa aatacgttac tgggaatatt atgatctaca agaaacattc
    12361 gatcagctat ttactcaaag tagaaacggg aaaaagtttt atcaattata tgagttaatc
    12421 atttctgaaa ataatattct tttagcatac cgtactatca aggcaaacaa ggggtcttcg
    12481 acaccaggaa cggattcctt cacaattgat aactataagg aaatgaacca agcagagttt
    12541 atccatctta ttctcagtca tttagaaaat tacaaaccaa aatccataaa gcgagtaatg
    12601 atacctaaac ccaatggtga gaaacgccca ttaggaattc catgcatgat tgatcgaatg
    12661 atccaacaga tgttcaagca gatactggag ccaatatgtg aagctaagtt ttatgaacat
    12721 agctacggtt tcagaccatt gagaagtgca aagcatgctc taggtcgcat tatgtatctc
    12781 ataaacatca gtaaaatgca ctatgcagta gacattgata tcaaaggttt ctttgataat
    12841 gtaaaccacc gtttactgat aaaacaatta tggaatatag gaatttgtga caaacaagtc
    12901 ttagctattc tttcaaaatc tctgaaatca cccattcaag gagaaggtat cccgagcaaa
    12961 ggaacgatcc aaggaggtat catttctcca ctattatcta atgttgttct aaacgactta
    13021 gaccattggg tctcaaagca gtggcatacc tttgaaacaa agtatcccta tactaaaggt
    13081 tacaataaat ttcgtgctct aagagataca aatctaaagc aaggctatat tgtcaggtac
    13141 gcagatgact ttaaaatcat gactaatgat tatccgacag cattaaaatg gttccacgct
    13201 gtcaagcttt acctaaaaga cagacttaaa ttagatattt ccaatgagaa gtctaaaatc
    13261 gtcaatttgc gtaaatgtaa gtcggaattt ttaggattcg ctatttgcgt gaaacaaaaa
    13321 gggaaaaaat gggtttgtaa ttcacgtatt tctaacaaaa aaaaggatca gattaaagaa
    13381 gagattaaac aaagaatcaa agatattcaa aagagtccta cagcacaaaa tgctctcctg
    13441 tttaatgctc tcgtgctcgg tgttcataat tatttcaggt atgccactca tattaattta
    13501 gatttgaata ggatgaacta cgttctttca ttcactactt acaaccgatt atcaaattgt
    13561 agtacaagat gttaccccaa caaagcttcc ccaacttaca aaaagtttta ctcaacaacg
    13621 atgaaaacgt ataaagtagc tggagtctat ttgtaccctc tttgcgacgt atctacaaaa
    13681 acaatttacg gatttaatac ggaggataca ccgtttactc cgtttggtcg tcaaagattg
    13741 gagcacaaaa gcctacagtc tcttgtgttc caagaattaa gaaaattgat ggaatcgaaa
    13801 ataccgaata gaacggttga gtatttagat agtagaatat ctcgttactc aatgaaatca
    13861 ggcaagtgtg agattacaaa acaatttttg ccagcaaaag ccgttcactg tcatcactat
    13921 ttgccaaaaa gtcttggtgg agacgacaaa ttcgataact tgagaattat tcataaggat
    13981 atccatcttc tgatccatac aacaaataaa atgataatcg atcactacgt gcatgaactg
    14041 aaactggtgc cagagcaaat agcaaaaatc aacctttatc gaaagatgtg taatctgcaa
    14101 aacattcaat agaaaataaa tagatggaac gccgtatgag gtgaaagtct cacgtacggt
    14161 gtggagcggg ggaaaagatg gagattatat caaattctta cctatcgcta tagatgttaa
    14221 cgacaaaaga aagtgcggtg attttgaata agcttaaaca aatcgtgatg ttaggccgtc
    14281 aatctggttt ctttctgatt ctagcttgtc aaaggccgga tgcgaaatat ctaggagatg
    14341 ggattcgcga tcagtttaac ttccgtgtgg ctttgggtcg tatgagtgag cttgggtatt
    14401 ccatgatgtt tggagaagtc gataaaaatt tttttatgaa acgcatcaaa ggacgaggtt
    14461 atgtagatac agggggcagt gtgattagtg agttttatac gccacttgta ccaaaagggt
    14521 atgatttctt aagggaaatt agcaacattg ttggattaac cgttcatacg gaaagagaaa
    14581 ataatagtgt gtagcctagg aatatcaata atcctgggct tttttattga ggtgatttat
    14641 gacattttta gatttattcg ccgggattgg tggctttcgc ttaggtatgg aacaagccgg
    14701 tcaccagtgt atcggttttt gtgaaattga tgaatttgct cggaggagtt ataaagcaat
    14761 ccatgataca aggaaggagg tggaaatgca tgacatcaca agtgtatcag acgaatttgt
    14821 tcgatccctc ggaccagtgg acatcctttg cggcggcttt ccgtgccaag ctttttcaat
    14881 tgcgggaaag cggcaaggat tttccgatac tcgaggtact ttattctttg aaatcgctcg
    14941 gttcgccact cttctccaac ctaagtttct attccttgag aacgtccggg gattgctcaa
    15001 tcacgaagga ggggctacgt tcgagacgat cctccgaacg ttggatggat tggggtatga
    15061 tgtggaatgg caagtgctta actcaaaggc ctacgttccc caaagccgtg agcggatctt
    15121 ccttatcgga cattctcgag atgcatgtac cgaacaagta tttcctatca ttggatcgtc
    15181 ttcaacatct gatcaaaaca tcagaaactt ggtaaatatc aatccttcca atcgaggaat
    15241 gggtggccaa gtctatggtt cagatagcgt agcaccaacc ttgaccggtg atgaaggaat
    15301 taaaattgcc ttaccggtaa aggatgggat ttctgtagcg ggtatgttgt cgggaaattt
    15361 tgaacaaggc aataggattt atgaggtaac cggaacagcc cccactttgt caacgaaaca
    15421 agggggaacg aagattatga ttcggaaaaa tgaaacagaa tatcaagagg tgaagccagg
    15481 ggacagtgtg aacctggctt ttcctaattc cacaagtcgc cgaggtcgtc tgggaaaaca
    15541 aagtgtgcat accttactaa caggagacca acaagcggta gtcacggatc agtaccagat
    15601 tcgaaagtta acacctaggg agtgctggcg gcttcagggc tttccagatt gggcttttga
    15661 tcgagcttct caagtcaatt cagatagtca gttgtataaa caggccggaa actcagtaac
    15721 agttccggtc atttttgata ttgctagaag attaaagggg gtaaaagcat atgatttatg
    15781 acgagttgat tggagaaatc tactggatga ttggcaagat tcaggcagat ccgaaattgg
    15841 aagaagaact gtaccggctc aattttgata ttcgcaaaaa cggggtgaaa gtccaggtga
    15901 ttcgtatgta gtggatgagg aaacggatgc tcgaatggag ctcaatcaag tcatcggtga
    15961 attggaacga attgcggacc ttgccaaaga acctgatatc cgccaatact tgtttgagat
    16021 aaaagcagag ttggaaattg agggtatcac cgcggagtaa tagggaaata acccactgat
    16081 aggcactgac cgcgggggat ttgcgaagca gaaatcctcc gtggtgctgt gcctgttcat
    16141 ggacggcggc agccggccat gatgtctcac cccccgtatc taacaggagg gtacaaaaac
    16201 acaaaaaaca agcaagtaac cataaaaaat gcttgttgta tcaaggatat taagtaattt
    16261 gtataggtgt taactcattt ggaaaagtta acaccttgaa tttggaggtg aaaacttggc
    16321 gcaacgaaat ttagattatc ggttattaaa agaacgacgc aacgaatatg gcgtttcaca
    16381 aaataaatta gctactgctt gcggacttag ccgcccatac ctaaatcaga tagaaaacgg
    16441 tggcgtaatc gcctctacaa agaccatgag aaaaattttt gatcaactgg aaagtttcaa
    16501 tcccgattta cctttaacgt tactatttga ctatgtaagg attcgctttc ccacaacgga
    16561 tgtgcggaaa attattcaag aaattctcca tttgaaattc gagtatatgc ttcatgaaga
    16621 ttacgccttt tactcctatc aagaacaata tgtcatgggc gatattgtag tgatgttatc
    16681 tcatgaagaa gataaaggtg tccttttgga attaaaaggt cgtggttgcc ggcagtttga
    16741 aactttttta ctcgcccaaa agcgtagctg gtacgacttt tttgaagatt gtctaaaagc
    16801 cggtggcgtg atgaaacgct tggatttagc aatcaatgat cgagtggggc tactggatat
    16861 tcctgattta acgaaaaaat gtcagaagga agaatgtatc tccttgtttc gtaccttcaa
    16921 aagttaccgt tccggggaac tgttgaaagc tgatgaaaag gatggtatgg gcaatacctt
    16981 atatattggc agcctcaaaa gcgaggttta tttttgtttg tacgaaaaag attatgaaca
    17041 atatatcaag ttagggattc cattggacca gaccgaaacg aaaaatcgtt ttgagattcg
    17101 gttgaaaaat gaccgtgctt attatgcgat tcaagatttg ttaaaaggtc gtagcattga
    17161 aagtaccacg ttttccatta tcaatcggta tttgcgattt gcggataaag tagatggaaa
    17221 acggcgaacc aattggccct tgaatgaaca atggggtcgt tttattggac ggaatcggaa
    17281 agagattcaa ttaacttctg aaccgaaacc gtataccatt gaacgaacat taaattggct
    17341 aggtagacaa gtcgccccta cgtggaaaat ggctaaggag ttggatcgat tgaatcaaac
    17401 aacgtatatc caggatatgg tacagaatgc gcgactctcg gaccggcata aaaagatttt
    17461 ggagcaacaa agtatggcaa tcgaaaactt gattgtatga aaagaggaat tttgatggaa
    17521 attgtaaaag atatgttatt ggtacttggt ggcagtatgc ttggtgttac cgtgatgtgc
    17581 ttgatgaatg caagtgcagc agcggattga gcaatggaaa agaaaggaaa gtgacaaaat
    17641 gaatttcgga caaaatttat gtgcgactcg ttccttagtg aaaagctaag gcactaataa
    17701 aagaacgaaa aagtttggtt attaggagaa ctgataatct gacaggtgga atgatgaagt
    17761 aacgctctga aacgcctgcc ctgagcctcc gacaagcatt gtatgaggaa actcagaatg
    17821 tttgaagctc ggtaaagacg gctgaaagat accgtaatag ttgatgaaca tatatcttct
    17881 atcgaaaact atccagaggt gggtagcgta tccaacaggt cgggggtcta taaaatatct
    17941 atggttagaa tgttctataa ggaactgacg aaacagcgaa tgtacgggtc taaatttgaa
    18001 ctttgtagaa atgcaaaggt acgagaaatc gtagctggtg tggcaaagta agaatatagg
    18061 ttatgaaatg ccatataacg ttacaggcgg tatcaagcca gcaggcttat agctagtgac
    18121 ctaaggatat atatgtatag ataagattat cggaacgagg aaaggtattg ggttctcatc
    18181 aagagaataa actgacgaag aacaataagc agttgaacta atgctgaaaa gcagagggcg
    18241 aacctaagaa attcttgtaa tgagaatgga ggaatgccct caagtcgtgt atatattaga
    18301 aaagtattat gttgtttcaa taaggattac gagtaagata aaaaagctca ctcaatttca
    18361 agtaaaggag tgaagcctta tgcctaaaaa taaaaatgaa acattgtgtg tagaagattt
    18421 aagacacgct gaatattacg aaatgcaaaa cacctttgat gatttatatg ccaaaagtaa
    18481 gaatggagat attttcactc atcttatgga tattatccta tcgagagaaa atatattact
    18541 ggcatatcga aatatcaaag caaatgcagg cagtaaaaca gcaggaacag acggtacaat
    18601 aattaaagat attggcaaat tgccagcaga aacagttgtc aaaaaagtaa gatacattgt
    18661 tgcaggcagt ccacatgggt atcgacctaa gccagtgagg cgaaaagaaa taccaaaacc
    18721 aaatggtaaa accagacctc taggtattcc ttgtatgtgg gacaggctta tacaacaatg
    18781 tataaaacaa gtattagaac caatctgcga agctaaattt agtgaaaaca gctatggttt
    18841 tagacctaat aggtcagttg aaaatgcaat aaaagcaacc tataaccgcc tacaaatcag
    18901 ccagctacat tatgtgattg aatttgatat taagggtttc tttgacaacg tgaaccattc
    18961 caagctgata aaacagatat gggctatggg aatacgggac aagcacttga tattcatttt
    19021 aaaaaggata ttaaaagctc caatcaaaat gactaacggt acaataacat atccagagaa
    19081 aggaactccg caagggggaa taatatcccc actactagca aacattgttc ttaatgagtt
    19141 agaccattgg gtagaaagcc aatggcagga aaatcctgtt acaaaaaact atgtggttca
    19201 tatcaataaa agcggtagcc catgtaaaag caacgcttac aaagaaatga agaaaacaaa
    19261 gttaaaggaa atgtatatgg ttcgttatgc agatgatttt agagttttct gccgctacaa
    19321 ggaaagtgct gaaaaagcca aaatagcaat cactcaatgg attgaacaac gattaaaatt
    19381 ggaagtatca caagaaaaaa caagaattgt aaatgttaga aaaagatact ccgactttct
    19441 tggtttcaag attaaaatga taccgagaag aaagaagtta gttgttaaat cacatataag
    19501 tgataaacaa ttcaaaaacc aaaaagacaa gctggtatca caggcaaaga aaattgcttc
    19561 tccctcaaaa gggaaaacgg aattagaaga aacaagactt tataattcaa tggtattagg
    19621 tatgcaaaat tattatcaga ttgcaacgaa tgtaaatctg gattgtatga aactgaatag
    19681 agctgtaatg gctatcttca ctaacagatt aggtacaaac aaaaggggca gattgagaaa
    19741 aacaggcaga caacttacga caaaggaggc aacaagatat ggtaaatcta aaatgcttcg
    19801 gtatgttgct ggcgagggcg aacctatttt ccctgttgga tatatccaac acagaaaacc
    19861 aatggcaaag gtgtatttag cgaattgcta cactctagag ggaagaaaat ttatccacac
    19921 caatctaagt gttgataaat tactgatgta ccagttaatg aaattatctt tggaaaatcg
    19981 cacaatagaa tacgcagaca atcgaatttc gctattttct gctcaacatg gaaaatgtgc
    20041 tataactctg gaagaatttc aacaagctaa tgaaatacat tgtcatcata ttgtaccaac
    20101 tggagctggt ggaaatgacg attataaaaa tcttattttg gtaaaagagg cggtacaccg
    20161 tctaatacac gctaaaacag aagaaacaat acaaaaatat atagctctat tgaagctaaa
    20221 taaagtccag ctcataagac taaataaata tagagtatta gctggcaatc aagaattaaa
    20281 cttgatatag gtctactaca taaatacttt tcaatataaa cacgatggaa cgcggagtgc
    20341 ggtgaaagtc gcacgctccg tgtgaatggg gggaaaagtt tgagatattt ataatatcag
    20401 gaacttacct atccatatat caatggtttt taaccaatgc tcaatcttta gtcttactag
    20461 cgattgtggt cattggtttg tttttaggat ttaaacggga gttttccaaa ctgattggct
    20521 tcttggtgat tgctttgatt gcggtaggtc tggtctttaa tgcttctggt gtgaaggatg
    20581 tcctactcaa tttgtttaac cgaattgtcg gtgcctgagg gggaatcaca atggaacaga
    20641 tgcgtgttta tattgcgaac cttggaaaat acaatgaagg tgagttggtg ggggcatggt
    20701 ttaccccacc tgtcgatttt gatgaagtga aagaacagat tggattaaat gacgaatatg
    20761 aagagtacgc gattcatgat tatgaactgc cttttgagat tgatgagtat acgccaattg
    20821 aagagattaa tcggttgtgt aacttagcgg aggaactaga aggaacgcca attggtgaag
    20881 ctgcttctga gattcaacac gctttcttca attctttcga ggaaatggta gagcatgtgg
    20941 atgatattgt ctattatcca gattgcgatg atatgagtga tgtggcgcat tacttgattg
    21001 tagaagctgg tgattttggc gaagttccag aacaattgaa gccgtatatt gattttgatg
    21061 cttgcggtcg agatttggag attggaggaa attatttggt tactagtcgt ggagtttttg
    21121 agtatccaga atgaatcaaa cactatatat agtgtttgat tagtatatgt aagcaaaaaa
    21181 acacaatata tagagtgcaa actgaagggt aatgtgatat aatatttgcc gaagaaatat
    21241 ttttgaaatg aggtaatatt atggcaaata ttcaaacaag ttttattgat ttccataatt
    21301 caattagatt ggacgtagaa gacaatacgc tacttaagga ctataaagac caagtaattg
    21361 atggattaaa agattactta cctgatgatg tgaagtttga aactttttta cagggaagct
    21421 attctgttta taccggaata aaaagctgtg atgaaaaaat tgattttgac atcgatattg
    21481 cagttgcttt cgaaattgat catactgttt atgaagatcc aagggagcct aaactgtggg
    21541 taaaagaggc gctagttgaa atttttccta atgctcaagt taatttaaaa gtaccttgtg
    21601 taactgctac atttactgga aaaaagacaa aaaaaaatgt gcacgttgat gttgcggttt
    21661 atgctaaaga agatgaaaat tatttcttag caaaagcaaa agaattcagt gctcccgaaa
    21721 accgatgctg ggaggaagcg gatcccaaag tattaaaaga gaaaattaat agtcatgtag
    21781 cagattcaga tgatcgaaaa caatttcgaa gatgtattcg ctatttaaaa agatggaaag
    21841 ataacaattt taaccaagaa tataaaccaa caggaattgg acttacaatt aatgtgatgg
    21901 atacgttcct agttaataag tccactgatt ttttaactag aaaagttcag tataatgata
    21961 tggaatgtat gaagcagatt gtttcttcgc tgaaagattc atttgtgtat gagtacagtg
    22021 aaacagatgg ttggcattat cgtctacatg catatcttcc agtgaagcct aacagtgaca
    22081 cctattcaaa aatgacagtg aatcagatga gtgattttaa aaacaaactt tctaaattat
    22141 atgatgattt gattttcgct atcgatactg aagatgagta tgaagctaca aaacgattaa
    22201 ataatcaatt tggggaggat tttttaatta tttcagaaga agaagttaca gaaaaaaact
    22261 taagaaatgc atttgttaca gactatccga gtgcttaggt tggtgttaaa gattggatta
    22321 tactgatatt ttaaaagaaa agctaacaga tgttgtgcgt ttattcgatg gtaattacta
    22381 tggggatttt tcatttgcta caattggaaa gttgcgttta aaaattgaaa taccaaaaca
    22441 ttttccattg gtacttccta ggatttacat tcataatttt gatcatttag gactttacct
    22501 accacatgta gaaaaagatg ggttggtatg tttttcttca gatataaatt atttagtaga
    22561 tgaagaaaat tcagaattgg ttttattgca gtgtgttaat aaaactataa aaacaattga
    22621 ggaaggtttg aaagggttaa ataaaaatga ttttcgaaaa gagtttgttg ctttttggga
    22681 caaacaagag aatcaaattt cgttattcta cctttgtgaa ccagcgttgt ttatcaagtc
    22741 agttgataca ataatgtacg gtaagtcttt ggttgctttg gataaagaga acgaattaca
    22801 attaaatgca gcgagtagat tgtttaatgg agagaaagaa gatactcatg aattagatgc
    22861 atactatgtt ccaattagaa acaagaataa tattatgccc ccgaagaata ataaagcatg
    22921 gtcaaagaag gatattttac aaatagtaaa aaaaaatgta acaggtgcaa ataaaagatt
    22981 ttttttaaaa cttgaaaaaa gaaagaatag acataatgtt ttacttattc tagatatccc
    23041 aattgaagaa aagtcaaata atgtcataat tggatttctt tttacaaaac aatctggatc
    23101 tataaaagat tataagggta cgcctaggac tgtattagtt cagcgtcatg atgaattata
    23161 tttggtgaat agaacgagcg gagaaaacta tggattgggt gctaatatag ctattgttgg
    23221 ggtagggtca gttggcagta aaattgctga aaatcttggt ccattaggtg tgagaaagat
    23281 gacactcata gacaatgatt gttttcaagc tgaaaatttg tatcgaaatt cacttggtgc
    23341 agatagttta aaaaatgccc gatctcagaa taattttttt aaagttgatt taatgcagga
    23401 ggagctcgaa aaaaaaatcc catacctttg tgttgaagtg gagtcaatga acgttttaga
    23461 cttaattagt atgcaacctg gttttttcaa ggaatatgac tatgtttttg tttgcatagg
    23521 agatacaatg gcaagcctgg ctttaaataa ttatttttcc aaaagtagtc aaaaagtttt
    23581 ctattcttgg ctggagccat atggcattgg gggacacact ctatttataa attattctct
    23641 aaatcaaaaa ggttgtttca attgtcttta tacagattca aactctaaaa ataggtgttc
    23701 aaatagagct tctctggtaa aagaaggaca aatttttgaa aggactttag cgagttgccg
    23761 ctcaaaattt ataccatata atgctattgc ctcgacggaa tgtgcaatta atgcaataaa
    23821 acttttccat aaagtcaatc aaaataatat gaccaatagt actctttttt catggatagg
    23881 agatgggagt acttttgaga atttaggata tcaatatagc gacagaaata cttttcttaa
    23941 tggagtcaat aagtttgaag aaagattctt ttctaaatat tgcaaagtat gtggggagtt
    24001 agatgattaa attttcgtgt gaccgtattg tcattgaagt aagggatgaa gttcttaaga
    24061 tatttgaaca atatcggcag ggaaaggatg acttgcctga agctggagga gttcttcatg
    24121 gaaaaagact taagaatggg agcataataa ttaccgatat aacaacacct caaataggag
    24181 atatacaaaa aagattactc tttaaaaaaa accgagaaat tcatcaacag ctttctaatg
    24241 agaaatggat agaatcaaat aagttttcta ttgcattggg agaatggcat actcatcctg
    24301 aagctgtacc aactccatca aatgttgata agaaaagctg gagactgaac gtgagcaagc
    24361 aacatgatga tagagtttat gtttttatta tcgttggatt ttctgatttg agaatgtggt
    24421 tactgtcaaa aaaatcagat attaggcagg ctataaaact ataaaggagt gattaggtga
    24481 aatcacaaaa gaatatttgg tggtgggggt ttttagtagg aaaggtaatg ataccagccc
    24541 ttctcttaat ttctctaccg atgattactt ttttctttac caataaaaaa atgagtaaag
    24601 aagccgtgat ttttttcttt ggagaccaaa aagctacctt tattgaaacg ttagtaacat
    24661 ctcttcagct taatttgaat tacatttttt caattattat tgttatatcg ttattgaatt
    24721 tttttaaaaa aagaaattca ggaaaggtgt ttaactctaa tggaaatgtg tactacaact
    24781 atttttattt tgtattttgg gtagcagcaa ctttacttgg ttatgataaa attcagattg
    24841 caggaattcc tatacacatg caatataagt tggttttgag tggaattttt tctgaggtgt
    24901 tgccagatat atacgatgat cattacgaca gtgatggaac atgtaaagta agcattgaaa
    24961 aagaaaattt cgatgacatc gatggatatg actctgtgaa cttactgatt attgatactt
    25021 acgatataaa aatgagtgaa ttatctatgg aaaatcaaac atatcctacg ataattgtta
    25081 gagggaattc aatagatgga gttcgtaaag ttaatagatc tttaatcttg gaaataaaaa
    25141 aaacaatgga tgaaattcaa aaaagtgact ttaaaaaagt atttgttgct tcaacatcta
    25201 atccaaaaaa tagtatcaat attattaatt catcgtttag atttttcggt cgatcacgta
    25261 ggtttaaact ttatgttctt caaaaggatt atgcaagcaa tggaaagtat agtaagaaat
    25321 atagaatttt tatttaagaa ggaatttttc cttcttttta ttttggagga aactatgaaa
    25381 aaaataaaaa gctacaccag tatttgggca gttgaaaaag tcatttatgc gattaatgac
    25441 tttcagctgc cttttcctgt gacctttaac cagatggctt ggtttgtttt atccttgatg
    25501 tttgtcattg tatttgccca tgtgcctccg ctatccatga tagagggggc ttttttaaaa
    25561 tacttgggca ttccgatagc ggtcacttgg ttcatgtcgc aaaagacctt tgacggtaag
    25621 aaaccattgg gatttttacg atcctttatc agctatcact tacggtttaa ggtcactttt
    25681 gcaggaaaga aagttaaaga acagaagaaa cgatgggacg aaccaatcac cttggtaagg
    25741 agtgtgaatt atgtacccga ttaagtatat tgaaaataat cttgtcttta accaagaagg
    25801 cgagtgtttt gcttactatg aattagtgcc ttacaattac tcctttttgt cacctgaaca
    25861 gaagtatcaa gtacatgata actttcgcca attaattgcg caaaatcgtg aaggtaagat
    25921 ccatgcctta caaattgcca cagaaagtag tattcgtgcc acacaagaac gttcgaaaaa
    25981 ggaaattacc ggtagactca aagaagtagc aaagcaacga attgatttac agacagatgc
    26041 attagtatcc atgattggcg atagtcagat tgattatcgc ttctttattg gctttaaact
    26101 gatttcgaca gatgaagagg tcaatctaaa gaatctcagg aaatctttct tttctggact
    26161 tcaagaattt gtctatggag tgaatcatca tttgatgggt gattttgttt ccttatccaa
    26221 tgaagaaatt cgtcgctata ccaagcttga aaaactaatg gaaagtaaat tggctcgaag
    26281 atttaaagtc aaacgagtaa cgccgagtga cttgacgtat ttaattgaac atatctatgg
    26341 tgaaaaaggc acaccgtttg aagaatatga attccagcta ccaaagaaaa agctgaaatc
    26401 agaaacgctg gtgaaacgtt acgacttatt acgtcccact cgttgtttga ttgaagaaaa
    26461 gcctcggtac ttacggatgg aacatgaaaa tcatgagtct tatgtagcgt acttaacaat
    26521 taataccatt gtaggggaaa tggagtttcc ttcctcggaa cttttctatt accagcaaca
    26581 acaatttacg tttccgattg atacttcaat gaatgtggaa attgtgacga ataaaaaggc
    26641 cctagctacc gttcgtaata agaaaaagga attaaaagat ttagacaacc atgcctatca
    26701 atctgataat gaaacgaact ccaatgtatt agatgctttg gattccgtgg atgaattgga
    26761 aaccaccttg gatcagtcga aagaatccat gtataaacta agctatgtgg ttcgagtgag
    26821 tgctaaatca gtggatgaat taaaacgccg ctgtgatgaa gtgctcgatt tttatgacga
    26881 taccaatgta aaactagtcc ggccctttgg cgatatgatg ggtctacaca aagaattctt
    26941 accctcaagt aagcgataca tgaatgacta tattcaatat gttacgtctg actttttggc
    27001 gggacttggt tttggggcta ctcaaatgct aggagaatta gaaggcattt actttggcta
    27061 taacgtagat acggggcgca atgtttacct gaaaccggca ttggcatcac aaggggtcaa
    27121 aggctcagta accaatgctt tggcatctgc tttccttggt tcgttaggtg gggggaaatc
    27181 ttttagcaac aatctcttag tctattatgc cgtccttttt ggtgggcaag ctgtgattgt
    27241 cgatccaaaa ggagaaagag gcggttggaa agaaacgttg ccagaaattg cggatgaaat
    27301 taatattctt aacttgacca gtaagccaga aaatcaaggc ttacttgatc cctatgtgat
    27361 tatgaagaaa aagaaagact cagaaagttt ggcgattgat atcctgacct ttttaacagg
    27421 gatttccagt cgggatgggg agaagttccc tgtgttacgc aaagccattc gaacggttac
    27481 ccaaagtgat cagcgaggat tattacaagt aatcgttgaa ttgcgtaaag aggactcacc
    27541 agtcgcggaa aatatcgcgg atcacatcga gtcctttacc gattatgatt ttgcccattt
    27601 gcttttctca gatggttcga ttacccagtc gattagttta gataagcagt taaatatcat
    27661 tcaagtagcg gatttggttt taccagatgc agaaaccact tttgaagaat ataccaccat
    27721 ggaattgctg agtgtttcca tgctaattgt tatttccact tttgccttgg actttatcca
    27781 tagcaaccga gaaattttca agattgtgga cctggatgag gcttggagtt ttcttcaagt
    27841 agctcaagga aaaacgttat cgaataaatt agtgcgtgct ggtcgggcca tgaatgccgg
    27901 tgtttacttc gtcacgcaaa acagtgatga cttgttggat gaacgtttga agaataatat
    27961 tgggctaaag tttgcatttc gcagtaccga tattcatgaa atcaagaaaa ccttggaatt
    28021 ctttggatta gataaagaag atgaaagtaa tcaaaaatgc atgcgagatt tggaaaatgg
    28081 gcaatgcttg atgcaggatt tgtatggtcg agtaggtgtg gtccaagttc atccagtctt
    28141 tgaagaactt ttccatgctt ttgatacccg tccgccagtt caagagagaa tggagtgagg
    28201 agatgaaaaa gaaacttttt cgtatctttg gaattgtttt aatcagtttg gtcactctga
    28261 taatactttt gagcttagtt ggaacggtag ctgaggcaac aggtctggtt gatgatacag
    28321 ttggagccgg aaatctttat tcccaatatt cacttggtaa ctatcagttg gatttctttg
    28381 tggatagttc gtgggattgg ctgccttgga attggggtga tggcctaggg aagagcgtaa
    28441 tgtatggact ttatgccatt actaatttta tttggacagt tagtctctac ttatcaaatg
    28501 ccacgggcta cgtggttcaa gaagcctata agctggattt catttcagat acggctgaaa
    28561 gtattgggaa gaatatccaa accttagccg gcattaccga aaatggactc cagacctcgg
    28621 gcttttactt tgggtttcta ttattgatga ttttagctct aggagtttat gtggcgtata
    28681 caggattatt aaaacgagaa actaccaaag cagtccgggc tgtcattaat tttgtgatga
    28741 tttttctact ttcgggttcg ttcattgcgt atgcgcccac ctatatcaca aaaatcaatg
    28801 attttagctc agatgtcagc gaagcggctc ttagccttgg aaccgagatt gtcgtgccga
    28861 attcagaaag ccaaggaaag gacagtgtgg atttaatccg agatagcttg ttttccattc
    28921 aagtccaaca accgtggtta ctcttgcaat ttgatgattc caatatagaa gaagttggcg
    28981 aagatcgtgt taacaaaatc ctgtctgtaa gtccagatga aaataaaggc aaggatcggg
    29041 aagaagcggt caaagcggag attgaagata atgacaatgc gaatctcagt attaccaaga
    29101 ccatgaaccg cttagggacc gtggtctttt tggtgttgtt caatattggc atatccttct
    29161 ttgtctttct cctaacaggg attatgttgt tctcgcaaat tctctttatt atctttgcga
    29221 tgtttttgcc gattagtttc ttattgtcca tgttgccgac ttatgagagt ttgggcaaga
    29281 aggcgattat tcgcttgttc aatacgatta tgatgcgagc aggagttact ttggtgatta
    29341 cgactgcatt tagcatctcc acgatgtttt tcaatatttc ggcaacctat ccatttttca
    29401 tggttgcttt tctgcaaatt gtgacctttg ccggtatcta tttcaaattg ggcgacatta
    29461 tgaatatgtt caatctccag agtaatgata gccaatcaat gggaagacgg gtcatgcgaa
    29521 aaccgcaaat gttaatgaat cgaacattgc ggcaactcaa tcgaaatgtg ggacggactt
    29581 tggcttttgg tggtggtgca gcagttggaa ataagttggc aaaggaacaa tcaaaatcca
    29641 aatttaagcc atccggttct tctctacgaa agaattcacg attaccgaac gatcacgaga
    29701 taccatctga cttgaataag gaaaagccaa ttccaaataa taagaaacaa tcccgaatga
    29761 atttggccgg gagaaaagtc ggcaaggttc tggataccca agctttggtg aaagataaga
    29821 ccaaacaagt aaaggatgga gtacggaata cgccaaccaa cttgaaatac aacttccata
    29881 aaggaattga aaaaacgaaa aaagcaccgg aagagtttaa gcgaggactg gtccaagaaa
    29941 aagcaaatcg aggagagttg cgagaaaaac aacaacaacg tagagacgaa aaaatagctg
    30001 aaaagcgcaa agtattgaac gaaataggga atcctcatgg gaaaagaagg gaaaatgttc
    30061 cgataaaagc aaaggtccaa tctcaaaagg atagagcacc aaagcggatt gtgagagcaa
    30121 attcgaatcc cgaaatcaaa cgaaaattcg ctagccaaga aatcatttca aaaggaataa
    30181 accaatcctc aagtaagaaa aattcttttc aacaagtgaa acggcggtct actctgtcca
    30241 aacgaaccaa tcgaaaagta caaaaaagtt tgaaccctca tcccaaacca aggtcaggtg
    30301 agaaaaaatg aacgtaaaga aattaagtgc catttcgtta actttcctaa caatctcttt
    30361 tatgggtatc ttgatgtgtg tgggcttatt gtttggtgaa gacagtgaag gaagtagtag
    30421 ttcaggtgct cctcctgggg ggagtagtgt ctcagaagag gttttgaaac accgtgcaat
    30481 ggtggaaaaa tatgccaaag aatcggatat aacagagtat gttccgattc ttttagcgat
    30541 tattcaagtg gaatctggtg gcacaatgga agatgtgatg caaagttctg agtcagccgg
    30601 tttaccaccg aattcattaa gtaccgaggc atccatcaaa caaggatgtc tctattttgc
    30661 gtctttggtt aagcgttcca aagaattagg ttgtgatcaa gatagtatca ttcaggccta
    30721 taactttggc ggtggttatt tggactatgt ggcaaaaaac gggaagaagc atagttttgc
    30781 tttagctgaa tctttttcaa aggaaaaatc ttgcggtcaa aaaatcgatt accctaatcc
    30841 catcgcgaat aaggaaaatg gtggatggcg ctataactat ggcaatatgt tttattgctt
    30901 attggtgaag caatacctaa ctacaacaca gtttgacgat aaaacagtcc aagggatttt
    30961 tgacgaggcg tttaagtatg aaggaacggc ttatgtattt ggtgggtcaa gacccgaaac
    31021 aggatttgat tgtagtggct tgactcaatg gtgttatgcc aaagttggtc tgaaacttcc
    31081 tcgggtggct caagatcagt atgatgccat gacccatatt gacctaaaag atgccaaacc
    31141 aggggatttg gttttctttc attcgactta tgatgccggt acttatgtga cccatgtcgg
    31201 tatttatgca ggggagaatc gcatgtttca tgcaggagat ccagtaggct ggacgaatct
    31261 aacagaaagc tattggcagc agcatcttat cggtgctgga cggtacaaat aagagaaaag
    31321 aggaaaaaga atgaagataa aaattgaacg gaatcaaaag gaaaagagcc taaaaaagaa
    31381 aaaagaacga gtcgtatccg tgggtaagca tcgaaaaatg gtgcttgccc tttggctttt
    31441 attatcttgt agtcttactt ttggcgttta taaaaatttc accgccattg atcaacatac
    31501 aactcatgaa aaagtggtta ttaaagagaa agtagtgaat acttctggta ttgaaaactt
    31561 tacgaaggat ttttcgaaag aatatttttc gtggaaaaat aacaaagaag caattgaaaa
    31621 gagaatgaac aacctcgaac agtaccttac agaagaaggt ttcgctttaa gtcaagatat
    31681 ggttcgagca gatattccca ctaattccga agttcagtca gtaaaagtct tagatgttga
    31741 aaagagctcg gaggaatttg tcgtttcatt tttagtggag caaaagatta cagagggaaa
    31801 aaaggcacaa tcgatttctt ctgcataccg agtgacgatc tttgaagatg aaaacaggaa
    31861 ttatatagta acgagtttgc caactatgat tgcaaaacct gatagggcaa aatacaagac
    31921 aaaacaagta gaaaatgatt cgaaaattga tgccaaaact acagaagaaa tcgctgagtt
    31981 tttggaaacg ttctttaaat tatatccatc agcttctgaa aaagaattgg agtattatgt
    32041 tgaaaatgat gcgatgcgac caatcaatat tgacttaaag ttttcgaagt tagaggatcc
    32101 agtttaccta caaaacggaa aaaaaattct agtgagtaca aagataaaat accttgataa
    32161 tgtatcaaaa accactagct actttcagta caaattaata ttacaaaaaa atggaaactg
    32221 gaaaatcatt gatgttaaat aataatgact caatctaaat ttatgagaag ttataagtag
    32281 tttaacttat ttcaggcaga agtcgcccat cctctatagg tgggtgatga atgccgttcg
    32341 gtaactcgaa aaccgacaat taagacatag tgccttttta ttttaatcca tgtcataatc
    32401 agtctatata agaaatggtt gatataccat ggaattagat acaaataatc attcattatt
    32461 tcttctttgt taccacctta ttttagtagt gaaacattgt aaacatctca ttgatgatgt
    32521 aatgttagct tatgcaaaaa actatctttg aaagaatatc agaatcacat cacattacct
    32581 tagttgagtg aaatcgtgat aaagactact ttcatattat gctcaaagca caacctaaaa
    32641 ccgaattaac aaaattcagc aatgcctaag ctcatgtctg ataaaatgag actttctaag
    32701 ggtcaaaaat ttcctttgaa tacgatcatt agcttagata aaagtaaaaa ccttagaact
    32761 acggggatag cttggttaat aagagatatc gctgttaata aagacataag cttgcaagta
    32821 tgctctattc ccaagaatct cccacttcaa gcactaagga tcgttaaatt cagctaagtg
    32881 gcaagtagtt cactagacga taattatctc catatttcaa tctcagcttt tccatttttc
    32941 atagcaaatt ccgttatttt tatagcatct aaaagattca gcttttccac tgatctttca
    33001 ccacttttca gcttttttat tgtgcttaaa ttgataccag taccttttga tattgaattg
    33061 gaagtaaaat cattaagggt tttttttatt aaattcatat ccgcaattcc agcgttcata
    33121 agaatgaaga ttctcctctc atagactact ttgaaaatgg tactacagtg gctgtttata
    33181 tatttcagta ggttactgta gtggtcattt tattataatt agaaaaggaa cctaaatcaa
    33241 aaatgctaaa gaaaattttc atagtattaa acctatcatg actaaagcca cggaattctt
    33301 gataaaagag tatacttgca agcctatgtc tttactaaca gcgatatctc ttattaacca
    33361 atctatcccc gttgttccta aggttcttga tgttttctaa ggcaatgctt gtatacatag
    33421 cccttgatca aaatattgat actaacgttg acgtttcgat catgatgtgt acggcaaata
    33481 ggacaagtcc attctcgaat tgtgaatgac ttcttaccat ctgtgtgtcc acattctgaa
    33541 ccaatttgac tagacggaaa tcatttatct atcttgatga tttttttgac agaagtatcg
    33601 aaaatcttta cataatctgg gtgttgcatt cttatgcaga tgagagcgtt agctccgtat
    33661 tcataaccag ttgcctctaa aacgtagtcc atcggtggat acctagcttg cggttgccag
    33721 tggctttcgc agtcttcttg taatcaaatc gagcatctaa ttgagtacta gtattttgaa
    33781 gataatactt gagtttttcg gttttcagaa gttcacttca tcttccatca tccatggaaa
    33841 tcccactcac ccatacgcag gcctccaaaa attcttcaac aatggttttt cagacatttt
    33901 tctgaatacc tccttgtttt ttgatacgcc agatagtcag gaaaaaggca acaaaacaca
    33961 aaacaaagct gcctaaaaag gtaatcttca ttccatataa aaagacatcc ggccgatctg
    34021 cgatatagtt agttactcgt tggcccatct tagcagacat cgcttgatat aagaccgtcg
    34081 tagaaagcga aatcccgatg accatcccca aatttcgggc aaaggaattc atggagcctg
    34141 ccagtcccaa attttcgata gtgacagaac tcataaccat cgtattattt ggggactgga
    34201 acaaggcatt gccggcaccc atgatggcag tagcgacaat gtacagccac aaaggagagt
    34261 ccactgacaa aaacatatac atgacttggg ttaccgacaa taaacccaag cctactaata
    34321 caaaaatctc cgggccaacc cggtcggtca ggtatccgct taaaggcgcc ccgacgacca
    34381 tcatcaaggg aaagaccatc atcaacagtc cggcatagct aggactcaac ccgcgagcat
    34441 tttgcagata aaaaggaatc actacattaa caaagaagtt ggaagaaaaa atcaacaagg
    34501 ctgtaatcaa gctcatggta aaaatcttgt tcttaaaaat accgaaagaa atcaatggag
    34561 aggctgcttt cttttcaact tttaaaaagc tgacaaaggc aatcactgaa attacgaaca
    34621 gtacaagggg gactggatgg aaaaagccac tttcttgccc caaaaagatt gttccaaaaa
    34681 ggctgataat cgtagccgca atggcagcaa agccccctcc atcgattgta tggccgctca
    34741 tggtgatatc ttttggtaag aatttttcag caatcaacat cgttacgatt cccaccggta
    34801 cattgatcca aaaaatgtac gcccaagaaa attgggacaa aatcaagccg ccaagacctg
    34861 gtccagcaat cgagcctaat gaaacaagcg caccgattgc tcccaatgcc cgaccacgtt
    34921 catgtatggg aaagacttcc gtgatgattc cggcatttgt agccatagtc atactagcac
    34981 caatggcttg taccacccgt gcgaacaatt aaatacctag cgaatgattg aacccacaca
    35041 acagcgagcc caagacaaag atcagcgtac caatccgaaa tactttgatt ttcccacagc
    35101 tatcgccaat tttaccaaac agcaacaaac aagaacagac aatcatcaga taaacggaca
    35161 ctacccattc cgcttgattc attggtatgc ccatatcatc tgagatggta ggtagtgcaa
    35221 tattgacaat actgccatcc aatgtggaca tgaaggtaaa catagatata gcaatcaaaa
    35281 tccaccagcg atttttttgg acttttgcat cttcttgata actatgcata ataggatttc
    35341 ctttctaatg atcgtgtagc taagaacaat ataacctatg tctactgccc aacaacttct
    35401 cgcgactcta gccataggaa gcttgagtaa tttcgatttg ttattctcat gtaaccatgt
    35461 aagtttgaga tgctttattt gaacttactc tatagtaact agtgataatt cgctttactt
    35521 tcttctagca atttctaaaa gtcgacttca ttgttcttca gattaatagt gtgagctatc
    35581 tcgtgagacg taagaaaatt tccattctac tttttcccaa ttttttcata tttatggtgt
    35641 tgcacctatt tgttttccaa tttgcttttc aaatacattg ctatgatatt caattccata
    35701 ggattatact aaatgtcaat agtatgaata atatattata gatgtttata tatcactgtt
    35761 aattattatc cacaataatt aatgattacc tcgatatttg tcaatcaaag gttgaaacaa
    35821 tttattttca gcatcttttc taacttgagc tgcactctta atagaatcat acgatcctaa
    35881 atagtacctc ttttttttaa agttatatac gcaatccatt tctctttaga acgataaact
    35941 cccttaacac cacttgtatt atttttcggt aattttgacg ttagacactc tattactgtc
    36001 ccttcaacac atgtccttgt ttcttgcctt tttaaacatc cacaactttg agtatgtcca
    36061 aaaaataagt tactataact tatctcacac atactgccac actcacattg acaaacccat
    36121 tttgttttcc atgaacagtt attgtccaaa ggatactttg cagtaagtaa tccgaatttt
    36181 ttattttcaa tgtgatgctt ttttgatttc aaacatccac agctttttac atcacctttt
    36241 agaagtcgct ttgccgatac taactttttt ctcccacaca gacattgaca ttcccaaaca
    36301 acagttcctt cacttcgcag tttagttggc ttgattgcaa ctaacttacc aaaagtttta
    36361 tttgtcaaat ttttatattt atgcctattt ttataatttc cacatccaca acttttggtt
    36421 ctacctgata gtaagtttga tcgatataca atcgtttcat tcccacagtc acataggtaa
    36481 cgatattttt tatatccatt atgagtaatc tcctcaacaa cagtaaggtg accatatctt
    36541 tccttcactg cacctaccct cccaagaaag aagtaccata taatttcaat taacttttaa
    36601 taaatcagaa aaaaatattt tcaatttttc ttagtctgat tttatgacta atttataata
    36661 caagactgaa cgatacgtac acgaaatcct caagatagat aaattgtttt catctagtaa
    36721 aacctgctca aaatatgagc ataaagacgg caataataca ctcgatattc gataatggac
    36781 ttgttttatt tgtcaaactc atcgtaatcg agatatcaat tccagtctca atatcctgat
    36841 caaaggtcta agaatccaac cattttcttg ttactttgtc agattgatta ccttttttag
    36901 tctccgaata ataaggtttt cggatcaact aacatgctct gagaaagact actatctttg
    36961 caaatttcca aatgaaggtg tgggccagta ctattcccag tacttcctac atagccaatt
    37021 atttgtcctt gcaaaacatt atctccagtt tttactaggt attgttgctg gtgagcatat
    37081 aacgcggttg atccatcttc gtgttgtatc accacgtaat ttccccaaga gtagtgaaac
    37141 tctgctttaa caaccttacc agctttaact gcatgaatcg gctcaccctg tgtagctgcc
    37201 atatcaagtc ctcggtgaaa ttcatttcca cgatttccaa acaaactggt tattgaataa
    37261 ttatgaatag gcacttggta tccagtctta ctcatttgtg gacctttaac ttctttatca
    37321 tagttggtta aatcataggt tttaattaat tcatttagct tcaaatagta ttgtgtatct
    37381 gttgcatacc gtcctgtaag gaatttagtt gcttctcgat atgttttact attagctttt
    37441 aatgctcctg cataaaaatc tttatttcca ctaattccct tagttaataa tttggcataa
    37501 tcttcaaaac tttcctcata gttttcatac actctaaatt ttgattgggt cgtataaagc
    37561 gttccattac ccaaatcttc gtttgttacc ataatgacaa agtttccatt ataagttcct
    37621 tttatcccaa ataaattgta attcggtgcc tgagctaact ggctttgacc actggcagat
    37681 tctaagatcg cttgtgcaat cataacagaa gcatataaat catatttctg accaattttt
    37741 ctcgcagact caccaatttt cataataaaa ttttctacag attcattttt gtcaaaatga
    37801 atttcttcat taccagatag tattggttgt gattggaaag attctgttga ttctatttgc
    37861 tgtggtgtcg aaaaattttt tgtttgtcct tccgtttttg gcgcttcctt ttttgaagac
    37921 tctatatggt ttggtcttgt cactttcgaa gaagttattt cacttgtact acttgaagtt
    37981 gttgaagatt cggcacttga aatcgtacta ctttcacttg acgaagttgt tgaagactcg
    38041 gcatttgaag tcgtactact ttcacttgac gaagttgttg aagactcggc atttgaagtc
    38101 gtactacttt cacttgatga agttgttgaa gactcagcat ttgaagtcgt actactttca
    38161 cttgataaag ttgtcaaaag ttcactactc tctgctgtta catcggaatt actcatttca
    38221 gtcgtctcgg ttctttcttt tgcaattttg tatgttgaat tttcgcttgc caacacatgg
    38281 aaaggtgttg ctataaagag ttgggacatt aatataactg ctgatgcaag ttttaaagat
    38341 tttttcattt gatttacctc tcttttttct ctttaatagt gttttctatt
//
LOCUS       DAYYEF010000023        37613 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000023 DAYYEF010000000
VERSION     DAYYEF010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.023"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(22..966)
                     /locus_tag="ACHA1B_001348"
     CDS             complement(22..966)
                     /locus_tag="ACHA1B_001348"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFM8702118.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1262..2206)
                     /locus_tag="ACHA1B_001349"
     CDS             complement(1262..2206)
                     /locus_tag="ACHA1B_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFM8702119.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2427..3641
                     /locus_tag="ACHA1B_001350"
     CDS             2427..3641
                     /locus_tag="ACHA1B_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM8702120.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3663..5678
                     /locus_tag="ACHA1B_001351"
     CDS             3663..5678
                     /locus_tag="ACHA1B_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HFM8702121.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(5761..7134)
                     /locus_tag="ACHA1B_001352"
     CDS             complement(5761..7134)
                     /locus_tag="ACHA1B_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFM8702122.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7160..7444)
                     /locus_tag="ACHA1B_001353"
     CDS             complement(7160..7444)
                     /locus_tag="ACHA1B_001353"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM8702123.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7446..9461)
                     /locus_tag="ACHA1B_001354"
     CDS             complement(7446..9461)
                     /locus_tag="ACHA1B_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFM8702124.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9640..9945)
                     /locus_tag="ACHA1B_001355"
     CDS             complement(9640..9945)
                     /locus_tag="ACHA1B_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HFM8702125.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10034..11065)
                     /locus_tag="ACHA1B_001356"
     CDS             complement(10034..11065)
                     /locus_tag="ACHA1B_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFM8702126.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11272..12147
                     /locus_tag="ACHA1B_001357"
     CDS             11272..12147
                     /locus_tag="ACHA1B_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFM8702127.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12299..13141)
                     /locus_tag="ACHA1B_001358"
     CDS             complement(12299..13141)
                     /locus_tag="ACHA1B_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFM8702128.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13233..15110)
                     /locus_tag="ACHA1B_001359"
     CDS             complement(13233..15110)
                     /locus_tag="ACHA1B_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HFM8702129.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15111..16529)
                     /locus_tag="ACHA1B_001360"
                     /pseudo
     CDS             complement(15111..16529)
                     /locus_tag="ACHA1B_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            complement(16532..19921)
                     /locus_tag="ACHA1B_001361"
     CDS             complement(16532..19921)
                     /locus_tag="ACHA1B_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFM8702130.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20178..21569
                     /locus_tag="ACHA1B_001362"
     CDS             20178..21569
                     /locus_tag="ACHA1B_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702131.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21642..22289)
                     /locus_tag="ACHA1B_001363"
     CDS             complement(21642..22289)
                     /locus_tag="ACHA1B_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8702132.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22297..22983)
                     /locus_tag="ACHA1B_001364"
     CDS             complement(22297..22983)
                     /locus_tag="ACHA1B_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702133.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(22989..24062)
                     /locus_tag="ACHA1B_001365"
     CDS             complement(22989..24062)
                     /locus_tag="ACHA1B_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702134.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24284..24958
                     /locus_tag="ACHA1B_001366"
     CDS             24284..24958
                     /locus_tag="ACHA1B_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM8702135.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            24963..26303
                     /locus_tag="ACHA1B_001367"
     CDS             24963..26303
                     /locus_tag="ACHA1B_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFM8702136.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26452..27438)
                     /locus_tag="ACHA1B_001368"
     CDS             complement(26452..27438)
                     /locus_tag="ACHA1B_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HFM8702137.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            28162..29193
                     /locus_tag="ACHA1B_001369"
     CDS             28162..29193
                     /locus_tag="ACHA1B_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8702138.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            29302..30834
                     /locus_tag="ACHA1B_001370"
     CDS             29302..30834
                     /locus_tag="ACHA1B_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HFM8702139.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            30973..31785
                     /locus_tag="ACHA1B_001371"
     CDS             30973..31785
                     /locus_tag="ACHA1B_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HFM8702140.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            31775..32260
                     /locus_tag="ACHA1B_001372"
     CDS             31775..32260
                     /locus_tag="ACHA1B_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFM8702141.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            32283..32828
                     /locus_tag="ACHA1B_001373"
     CDS             32283..32828
                     /locus_tag="ACHA1B_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HFM8702142.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(32901..34544)
                     /locus_tag="ACHA1B_001374"
     CDS             complement(32901..34544)
                     /locus_tag="ACHA1B_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HFM8702143.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(34673..36901)
                     /locus_tag="ACHA1B_001375"
     CDS             complement(34673..36901)
                     /locus_tag="ACHA1B_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM8702144.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            complement(36934..37413)
                     /locus_tag="ACHA1B_001376"
     CDS             complement(36934..37413)
                     /locus_tag="ACHA1B_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6530 family protein"
                     /protein_id="HFM8702145.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
BASE COUNT        10954 a         7137 c         6860 g        12662 t
ORIGIN      
        1 ttagttcata ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt
       61 tgatttgctg aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac
      121 accattttcg tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc
      181 agttaaataa gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat
      241 acgtgcagta ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata
      301 agcagcatta cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc
      361 tttttctaca atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac
      421 ttctgaatca ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa
      481 tttcaatgcg atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac
      541 acgtgatgtt ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt
      601 tgaagcaaca acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg
      661 catgattgac gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat
      721 accagctgtg ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac
      781 agccacattt tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc
      841 tttttcttga ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc
      901 ataagcgata cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt
      961 tttcatgaat aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct
     1021 tgtttattca ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa
     1081 acgaattcct gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat
     1141 aatacaacca aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa
     1201 taagacagca atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt
     1261 cttaatgttt atttctccat tcattgggag tacatgttga atacttcttg aataatttga
     1321 ataaagaagt cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg
     1381 tttcttgaat cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg
     1441 aagcatcaaa atacattttc aatttattac taagatagac cggattgtag ccaaaatgag
     1501 ctgctgtttc ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa
     1561 gcatctcatt ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag
     1621 tcaattcgat cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg
     1681 tatcaaaata aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc
     1741 cgcgaaaatg aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag
     1801 aagaaagtag attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt
     1861 cttttaataa gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag
     1921 cttctttatc aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa
     1981 tttgtaaaca tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg
     2041 gaacttccgc atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc
     2101 ctcggtggat ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca
     2161 ttccttgttc acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat
     2221 tcagctagtt ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca
     2281 cgctgtactg ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg
     2341 gacatgaact tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga
     2401 taagcgctta caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc
     2461 tgctgtcagt ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta
     2521 tgtcagctac ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct
     2581 cttttatggt cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa
     2641 aacaaactgt gatcatcgga ttagtgattg catcgatttg tggtatcctc cccctcttct
     2701 cacaaagtta cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga
     2761 tcaattcttt ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta
     2821 tgattggttt tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag
     2881 gacagctagt acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta
     2941 ttcttgtctt gtttgttttg tttgttccta cacctgaaac aactgaactt caatcgcatg
     3001 gcacagcccc aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt
     3061 ttctcttgct ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga
     3121 cgacttattc tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg
     3181 caagtatggc tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc
     3241 ttacactttc tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc
     3301 tgtatgtgat tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt
     3361 acttattcaa ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa
     3421 tcttattggt tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct
     3481 cttttgcttc tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt
     3541 tgattagcgc gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa
     3601 gagtagatga agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta
     3661 aaatgacaaa tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc
     3721 gccatggact gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact
     3781 ggtacatgga tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac
     3841 cttccatgtt taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac
     3901 atccatgtgg aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag
     3961 gacatacatc agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg
     4021 gctggacagc aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg
     4081 atatcgcaaa agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg
     4141 aaacggagat tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag
     4201 aactaatatc tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg
     4261 tagaagctat ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga
     4321 aagctcgtaa acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc
     4381 aacttcaagt ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt
     4441 cttctttact gaatcagatc tggtcagtat cagaagaagc cttcaagtta tgtagtgatt
     4501 tgttttttat cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat
     4561 cattcatgat caatcaatat cttttttttg acgaggaaat caataaacga acgatattag
     4621 cattaagagg acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct
     4681 tgtggttgat tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca
     4741 tcgtctaccc taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag
     4801 ggtttattta tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag
     4861 aaggaacgct tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt
     4921 gcggagatat cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc
     4981 aagaaaaata tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg
     5041 gcgcttttat cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt
     5101 tcgctgtttt attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct
     5161 tattgaatga cactatcaca cagattacta ctccatattt caaattctat gaacaagatg
     5221 ctttatgcaa actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag
     5281 ggatgttatc tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa
     5341 atgaaaagta cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag
     5401 caagcccaat ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt
     5461 atgaagaatt tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac
     5521 ctatcaaaga tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg
     5581 atagaacagg cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc
     5641 cacttgtctt aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat
     5701 atcagaagac tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc
     5761 ttaattctgt tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa
     5821 tacgacaagt aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc
     5881 tagtttccca agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc
     5941 gattttaaga tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct
     6001 attgaaagca gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc
     6061 agaagcagct ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa
     6121 gcctatcata gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa
     6181 tacagcatta ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg
     6241 tacgagtttt ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac
     6301 cccttgaagg acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat
     6361 tacagcgttg tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc
     6421 aagtgcgaca tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa
     6481 gctgaaactt ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt
     6541 tccgatccat ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt
     6601 gtttccagtg atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt
     6661 tccttcgaag accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac
     6721 taaaatgact gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa
     6781 tttatatctt gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa
     6841 agcagtaggt gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac
     6901 tactccttga gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact
     6961 gattaaacca gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg
     7021 gatcacttct gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac
     7081 gaggatggag ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag
     7141 ttcctccctt gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt
     7201 cttcgctgtc aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg
     7261 tatctttcaa agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa
     7321 catccgtatg acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt
     7381 tgatgttcat ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt
     7441 tcatatcatt cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt
     7501 aataaatctt gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga
     7561 agatgtgcct cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga
     7621 ttatcaagca gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg
     7681 ccatcttctg gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca
     7741 tactgctcca cgcgctcgat catagctttg atataacttt cttctatttt attttctgat
     7801 aatagcggct gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat
     7861 tggatcattt cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct
     7921 aaaagtttgt tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct
     7981 tttaattcga tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat
     8041 cctggtatca gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc
     8101 atgattggat gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta
     8161 gaaaaaataa tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc
     8221 tctgtaaaaa agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag
     8281 ctaatgccac ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc
     8341 gcttttctga tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg
     8401 ctcttcccta ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa
     8461 gcatattgat gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata
     8521 cgaaaatagg cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca
     8581 aattctacgg ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa
     8641 aaatcaagtg caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa
     8701 aatataatct ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta
     8761 atgtcagtga ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt
     8821 tttccaattc gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt
     8881 gcgaatcgaa gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa
     8941 taatcaatgg aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc
     9001 atcaaacgag cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc
     9061 ctaaaaccag ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt
     9121 atctttttga tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga
     9181 aaaacagaaa cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct
     9241 tgttcggtat acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt
     9301 gctcggaatt tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat
     9361 tgtttgatcg cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt
     9421 tctcttggtg ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac
     9481 ttatattcta gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg
     9541 atttttttta cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg
     9601 accaaatgtc tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt
     9661 ttttgaggtc agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt
     9721 ttcaaagtga ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa
     9781 agctgtttct ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc
     9841 ttctgtttca ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat
     9901 tgaacctctt aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag
     9961 tagttctata ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat
    10021 tcttacaaat atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca
    10081 aaattttcat ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta
    10141 atgtctcgta aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt
    10201 cttcatgata actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat
    10261 cgataccaaa gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat
    10321 cttttgtttg tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt
    10381 tgatgcggaa ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat
    10441 cgaagtaatc attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat
    10501 ctggttcgcc gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat
    10561 agctgttcgc agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat
    10621 aatgcatttc tacttctaaa atatccccta attttccgct ttcgattact ttttggactg
    10681 tcaagaagtc agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt
    10741 ttgctaatgc aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta
    10801 gtacattctt accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg
    10861 tagtgatgac aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat
    10921 attcgatgtc ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat
    10981 tgattttgtt cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat
    11041 tgccaagata agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata
    11101 tcctagaaaa gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac
    11161 acttgttatc attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga
    11221 tagtagcgga accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt
    11281 gaagaaaaac taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac
    11341 atccgtagga atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg
    11401 tatacttccc attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa
    11461 gaattccgtt tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg
    11521 attgatccta attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg
    11581 gcggatttat cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta
    11641 gatcaaatcg gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat
    11701 tctcaaatca cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc
    11761 atggctgaag aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc
    11821 gccattttta ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg
    11881 aagcatgtag aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa
    11941 caggctgata tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact
    12001 ttctcctctc aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct
    12061 caaaattttg aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc
    12121 cttcttaaag aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag
    12181 tgtttgatag gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac
    12241 ctcagcctgt ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct
    12301 aacttctgtt tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca
    12361 gtatacatgc agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta
    12421 cttctttttg aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat
    12481 gactgttgac catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga
    12541 ttctcagatc ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga
    12601 gtgtccgtcc attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg
    12661 tgaacaactt tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc
    12721 cccccgtagg ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat
    12781 tcgtttcatc aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg
    12841 tatgtttctc aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat
    12901 ctgcacctgg atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt
    12961 ggattttagc catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga
    13021 tctgctgatc cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta
    13081 ttcctgagag aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca
    13141 tttgtgttct ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc
    13201 cgctgctcct ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca
    13261 aagtacagtc cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc
    13321 ttaccgcctg ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc
    13381 aactgtcctg ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat
    13441 ggaacatatt tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct
    13501 gtcacatcga ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat
    13561 acccagctga cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct
    13621 tgatcacgaa cgacgaattc tgctccagca agtgtttggt ctgatgtaac gtcaccatct
    13681 actttaacaa atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt
    13741 gtatgcccgt tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg
    13801 ttcaaatgca tatagtaaac gaatttcaat gtaccgccag gagttaatga aggaatataa
    13861 ttcggatcaa ctgaaaccgt gaatccgtct gtttgctcag tgacagaata atttactggg
    13921 tcgatttctt tatttccatc atataaggca taagcatacg ttcctgaaga atcattatca
    13981 aatgttaaag cagcgtcatg agtatcgata agtttgaatg ttgtgtactt gttttgcgtt
    14041 ccttctttat cagcgatacc taatgggata ttgacagaaa tctcatattg aattttttca
    14101 ccgattgcga catcttttcc attcaattga ggtgttgttt tatcaacttt agacgtatca
    14161 tttttgatgg tcttttctac tggtgtttgg ctatttgcca ggatctcaaa aggcgtgatt
    14221 gtttgctttt caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt
    14281 ccaacttcta aatgattaac gatcaactgg cctttttcaa tagatgcctc ggcaaagtca
    14341 ttgttgccga tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatcagtt
    14401 gtccaagtgt acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtgttcct
    14461 tcttctttag aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt
    14521 tttgtaactt tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta
    14581 tctagttctt ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca
    14641 gggaaagcta aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc
    14701 gtgtagactg catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca
    14761 gcatctgtcg ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt
    14821 gctgcatcca cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa
    14881 actgaaaatg aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg
    14941 ctgttttgga ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga
    15001 gctgctgtct cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa
    15061 ataaggaaaa ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc
    15121 ctgttctttt ttttgataaa caaccagatt gcaaagcttg cgaataccat accaacaacg
    15181 cctaaaagtg tatttttcgt ttcgtttgtt tttggaagaa atggacggct attttctttt
    15241 ttattgacta ctttcaatat actgtccgcc tctttatcct cagaaagaaa agttgaaatg
    15301 gtaaacggaa tttctgtttc acttaaaata taaccagaag gtgcttcgat ctcttttaat
    15361 cgataacttc ctgttttcaa cccggaaatt gaaaaagcgc catttttatc ggaaatcagg
    15421 tgaagcgcat ctgattcgtt ctttgtccac ttgtatccgt tggctgtttg ctggaggtaa
    15481 tttcctgctt tgtttttaat aaggaatact gcgccagcta atcgtttatc tggtttattt
    15541 gtctcgattt tgacaaattg cttactccct gtatatacag agactttctt tgtactgaca
    15601 ccaaaaccaa aatccagtgt tccgttgttg ttgatttcct tgttcgcctg tgctgtactg
    15661 cttagctgca tctgataaga aatggtcagt ttttttccag catatttttc caacgaaggg
    15721 atcgaaaata aaacatcaaa tccgtgaggt ttcttgtgta tgacaaagcc ttctgtcagc
    15781 ttttctccat tcgatgaaat cgttaaacta ttaggtaaaa acgttaatgc ttcatccgca
    15841 ctatctgaca attcgaactt ttgatagtca aggatattta caggaattgt cgtatgcaag
    15901 gaataagtga ttttttcacc aatcgtaaaa tcatttctag gctcttctaa taccttctca
    15961 aaaggtggat cagggtagtc gttttcttca tttttaggat acaaatggat agttgaaagt
    16021 ttttgattgt tttgtccatg tacaggaaga acaactacca tattctctgc cttttctttg
    16081 acgacttctg gtactttgga ttcaatgaaa agatacgctt tatctctttt ttcttgatct
    16141 ttagcggcca gagaaaaaga agcgatacca tcttcgttgt taagagttgt agttgttgct
    16201 tctgcggtaa acataccgga agacgcaccg ttttttgcga tctctgcttg tgcttcttct
    16261 accgttttgc ccttttcccg tagatggtaa aaagaatctg tgacatcata aacttggaat
    16321 gtgacaccat ttaatcctcg atacgtttgt aataaagctt tttcttgtcc gtcatttgga
    16381 tgatttttcg gcagttgccc gtttgggaaa agcaatttgt gtaaagtaat ctgaaccatt
    16441 tctgtttctg tttctgttgc tacctgagta aaagctggtt taaatagtaa caagaagaga
    16501 cacatactaa gccaaccaag ttttttcata tttagctgcc ccctctttct tttttcaaaa
    16561 aaagatacca aatagaaaac gcacaaccaa tcatccctac tagatagatt cctaaacggc
    16621 caattcctcc cgtttcaggt aatggtactt ttgcctgatt cgtgatgtct aaagaaatct
    16681 ggttgttttt ggctcctggt gacagaacag attcatgatc ttgtccatcc acttgaattg
    16741 acccatcttc gtgtataact atagtaactg gctcttttag accttggtat ccttctggtg
    16801 taaaagtttc ggtcagcgta taagttccag gttttaaatt ttcgaataga aaggtatctg
    16861 tttcttgtcc atcttttggc gattctaagt ccatttctgg tccctgcagt ctgaattttg
    16921 ctccttttaa tgtctgtccg ttgtcttctt ttttgtgtac cgttagatca aacgctttta
    16981 gtcgattttg atgagtgagc gtccatacat tatttgtcat ctcggtattt tttcccgtgt
    17041 aaatgatttt tccatattta tcgatttgga attcataatt tcccggcgaa gtatcatatc
    17101 cggcaggacc agctgtttca acgactcgat atttaccagg tgtgagtgaa tcaaaactgg
    17161 caagaccttt ttcattcgtt gtttggctgt caattggctg ataagtacca tttgcttctt
    17221 ttttctgtag ggaaaatgct gctcctttaa gatttatctc tttgtccgtc ccttgcatcg
    17281 catacttacg tactgctaca ggaacttcaa caaaaggatt ttcaatagtc aactggatcg
    17341 tatcatcgga agtagtgact gtttttccat caatggttac cgtaccatca gaagcgatct
    17401 tgatttccca agtagtcttt ttgcttaatc catgcccttc tggagctttt gtttctgtca
    17461 gcgtataggt catttctttt tgcaatttga cattttctgg aagagaatag gttccgtcgc
    17521 catgatctgt tagtaaagta tcaatagaat ctcctgttaa tttgaaaaca gcgccaataa
    17581 gatccttttc acctgtagag gaatttttcg ttattttcaa gtttaacggt gtgaattgtt
    17641 tagtattttt ccatgtcatt gcatctattt gttgagaatc gtatcctggt acaggtaatt
    17701 ctttgattgt ttggtaactg aatgcttgac cttgattatt gtattgaggt agtgataata
    17761 tctcttgata actttctccg ctatttgcag ataatttgtc aatgtctgca cgttcccacg
    17821 tatttgttgt atctttagct ggtttaatga ttcgaatata tccgtttttc caagctgcag
    17881 catttgtcgt atgttcccgt tgaatctcaa aagtaacttg atctggacga tcagctagat
    17941 tgttgtcaaa ttcttcccat aactttttga tgtgaagact gactccggga gctttagcag
    18001 atggtatacc gaattcagct aattcattgg tatcaatgtt tggctggaaa gttgtcctgc
    18061 cgttcatttg ataccagaaa tttggatgga agtcctcatt ttctgtttgg attctcactt
    18121 ggtaatggat ttggatttct tggtcttttc ctaaatagat ctgattgctc ttgatggtat
    18181 ttccttctat ggaaatagat ggagtgaccg ttgtaggact tgtccccaca ctcttgactg
    18241 aaagtgtacc aggctgataa atgaatggtt ctgcgattgg atcatttatt tgtccattgc
    18301 ttacagttgc tgagatctgt acagcttttt tggctaggta ttcagagata tctgttgcat
    18361 gatcagctga ttcatagtaa agatcgcctt tttcatctga tgaaaccatt tgtcgcatac
    18421 gagactctac ttctgctttt gagagaccag ctgccggatc gctttgaagt tggatgccaa
    18481 gaccatgtat ttcgattcct cgttctttga gtgccatcgc ttctccgatg gttgcgataa
    18541 acgtactgtc gattcttctg gatagattgt tttggtcagg tgcatcatag attcttgaga
    18601 ttagagaagt atttcccggc cgatcttgcg tattagaaaa ctgagttccg taataattgc
    18661 tgcttgattg tgcgtgtacc cgctgtactt tataggaaaa tgttggtaca ccatccgtca
    18721 gcaaaacgat cactttttta tgtccatttg gaacggatag catgcttcct gcatctctta
    18781 gtgctttttg tgtaaaagta ccaccatttg tccgtgaagg tgtaatggat tttacttgat
    18841 ttttcactga atcaaatgaa cccatctgta ctgcaccgtt actgtagcta tatccttcgc
    18901 ttgagtagcc gacatatccc atattgattt tgtctgtgat accgctatct gctaaagtat
    18961 cgacaaaacg atcgacacca atctttactt caccgatccg attattgtcg ttcatacttc
    19021 ctgaccagtc tacgaccaat acgagatcaa gaggcgtgat atctttttgt acatttccac
    19081 gagcattcaa ataaacatca aacaatccgg gtgtacttgt ttcctttgca tactttcgta
    19141 tcgcatagtc tgcttgatta ccggttcctc catattcgat atacgaatgg gtccgatcat
    19201 taggatctcc attccaagaa tttataccat cccattgatt tgttccgttt ttattgcctt
    19261 gatgatcaag aacatttgta tttcctgtag gttgccaact ggctttagga taagtgccct
    19321 gatcatctgt tgtatattct gtaggaatcg tttgattaga tggcacactc acagctggca
    19381 aggataatgt aggcaatgta aatgggctga cagaattttc gttttctttt gatgattctt
    19441 cttctatttc gtctggcttt ggtactgaca catctgtatc tttcttattt tctgtctcat
    19501 caataatgtc atattcttta ttatcgacga tcagcttgtt tgcctggctg tggtaaagtg
    19561 ctggatcgat tggaaaactc agatcgatag tttgtttagt gtttgatgag atttccaacg
    19621 taattttccc gctatttacc tgataagcat agccatctcc ttcttttctt tccacatcac
    19681 ttaagtaatt ttcgactaga ccaatttctt tttctatctt ttcagcactg gtgttattcg
    19741 catttagctt gatgttcagt gctttttttc cagactgatc cgaaatgact tcagctgaaa
    19801 ttgtttctaa aactgttgga tcatctgtag tgtctgctat tgcagataat ggcacaaagt
    19861 ttgataaact caatattatc agcatgaaaa taactttcag tttcttccct gtggtcgtca
    19921 tttttcccct cctttttctt tttttctgtt ttgacgtgaa tagtgaaaat tattaaaata
    19981 aacaggcgtt acataatttt atttatttta atatgataat tattatacga agggcgctaa
    20041 agggaatcac accaattttc ataccaattg gtttcattta tgaagttgat tccttcgatt
    20101 aatgagcgtt tcattgaaag aaaagggttg agggagaaaa acatatgatc aggttgttgg
    20161 aattaaacta tagaaagatg gaaaaaatca ttcgaattct gtccatttct gacaagtgga
    20221 tgactaaaaa agaacttgcc aaacgaattg gtagttcaga atctacattt gtaaggtata
    20281 tcgaagagat caaaatccgc tggggaacgg atgtaacgat tcaatcttca caaaaattgg
    20341 ggtatcgtct tgaacatttg aatgtaccag cttatttaaa tgttctgatg gaaatgtcgc
    20401 aaagttctac aaacagtcgt ttattaaatg agattattgt caatccgggt aaaacgattg
    20461 agtattattg tgaaaaaatt tccatcagcc ggtcttcttt tacacgtaag ttgaaacaat
    20521 gcaatcaaat tttagaaagc tatttattaa aagtgatcgt tgaccaaggt tttcagttaa
    20581 ctagccttaa aagtgagctc cagttgcgta tctttgttac ctttttcttt ttaagttact
    20641 acggaagacg cacgttgcca tttccaatcg aaaaaaagaa gatcaaagaa attatggtca
    20701 agaataattg tcagatgaat ttgtttcagg aagaaagccc atatgagcaa tctttcttta
    20761 ttatgtattt tgttgtgcat ctcatgagag aatcccaagg aactccattt gaatggaaag
    20821 ctggagactc ttatgtacag ttgataaata tcgataaaaa agacttctta atcttgaaaa
    20881 atctcttagg aaaattgaag tacagcagct atataaaagt agtgaactat tttgtcaata
    20941 cgattttttc agaattttcg gagaaagaaa aaaatgaaat cagtgagcag atacgaaaaa
    21001 atatgtccta ctgttcgttt tcatccgctg attgcaaaga aaaaaacgaa gaatatgttg
    21061 ttcaattatt aacgcaaatt tattttttct cccgtatttt cccatacgat acgactcatt
    21121 tgacgatccg tgcaacttac tttgcacagc agatgcaaca ccgccagata cgtctatatg
    21181 ctggatttcg tgcagaactt caattttatt ccactctact gaatcagaat ctgatttatt
    21241 atttatctag ctatatcttt tggatgctta tcggtaatcc tgaaattcac cattatactt
    21301 ctgataaaaa aatactgatt atcagcgact taagtcttcg acatagtcaa tatattgaag
    21361 aatatatcag tgatattctt gctgtgcata aaattcactc tgagacaact gctattactg
    21421 aagatcagct gtcgaaatac aatcttctcg agtatgatct gatcgttacg aatcaaccca
    21481 ttttgaatgc ccatgttcct catatattga ttgatgatag tgtgtcattc gcaaatgaag
    21541 aagaactcat ccgcttattc gagttatgaa taatcaaaaa acagctatgt ataaaccacc
    21601 ctgataaaaa tttcaggaca aatacacata gctgtttctt tttattgtat tccttcagca
    21661 atccaacgag atttatagcg aaagtctttt aacaactctt cttttgtcca attatttgca
    21721 atgagatccg tcaaagtgtt cattacgagg gtcatggaaa agtataggaa actaactgct
    21781 tcttccgacg attgaatgga gaaatgattg attcttaata attccagcca tttttcgttc
    21841 attggagaat cagccgatag ttctctacgt ttggttgtct gctgatcatt tcgctgggtt
    21901 aacaagtata acctttgcca atagatactt tcgtgatcta agtcgcagca ccactctaaa
    21961 tatttttcga tccccaaaaa gaaatgttgt ttgttttcgc taatgaattt taagatatct
    22021 tgatggacta tgtgagaact gcttttgatc gtatacaaat aagcatcttc caaatcttga
    22081 aaatatttat aaaaagcacc gcgcgacatc cccatcttgt caacgatttc tgagactttg
    22141 acttggctga tgtgctgtga gcaaaatatc tccagtaata ggtcatcgat tctctgtttc
    22201 tttgcgttcg ataaattgaa aaaagtttct tttggcatcc acatctctcc tttatctctg
    22261 attatacgtg gatagccctt cattgtcatg aaggattcat tccttctttt tctcttcttc
    22321 tgtcaagtac ccatcttcca ttcgataaac gcgatcactc cattgaatca tacggacatc
    22381 atgagtaacc ataatagtcg ctttttgttt ctcatgagct tctttaacta gtaatttgac
    22441 gacttcatat gcatgatctg tatccaaact agctgttggt tcgtctgcta agatcaagct
    22501 tggctcatta tataaagcgc gagcaattgc cactctctgt ctttctccac cagaaaggtc
    22561 tttaggataa ctatttttaa gtgactggat atctaaagat tgcagcaagg aatcgatttt
    22621 tgttgaatct tctttttttg aagtaacttg gtcaactagt tcaaattgtt cctttaccgt
    22681 taaaaaagga atcaaattag agctttggag aataaatcct atttctttaa agcgtaaatc
    22741 tgctcgtttt ttttctggaa gctcagttag tgagtgaccg ttgatcacta tttctccgga
    22801 agtcggtgtt tgcaatcctc ctgaaatggt aaggaaagta cttttacctg aaccagaagg
    22861 accaatgatg ctgacgaatt ctccttcctt tacataaaaa tcaattgctt tcaaagctga
    22921 gacctttgta tgaccagaac caaatgtttt ggtaactttt ttcatcgtta atattttttt
    22981 catttttatt aacctcctat tgctgtaatt gggtctactt tggttatcgt acgtatcgaa
    23041 aacaatccgc ctagcattgc gacaatgatc aaaatcccac tatatagcaa ccattgtgac
    23101 caaaaaacag caaaaggcat cgcgcttggt aaaatcagac tagtcaaata agcaaacaaa
    23161 agagcaagca gaacgcctac caccccaaca ataaaggact gtgctactaa agatttagcg
    23221 atgaagaaat ttttgatccc ttgtgctttc attactccaa aaatagcagt cttctgaagt
    23281 gtcatcacgt acatgaaaat accgaccacg gcagcaacca ctaagaacaa aaagtatatc
    23341 atcgcattta aggtcatatt ttgggcagaa tagccaggaa tactttcaat gaatgtccca
    23401 atagttaata actgtagacc cttcgatgct ttttctttcg aaattttagc tgaatccttt
    23461 attacgatcc cattgatcgg ctgttcttct tcagaagcaa acggctgttg tccatacttc
    23521 aaagcagtcc acgtatctag ggacgcatag atgacgggag aaactgtgta ataagtttca
    23581 ggaaagatac cgacaatcgt caaaggatcg tcgtaactgc caattttgat cgtatctcca
    23641 attttatagc ctgaatcagc cagattttga gagatgatga tttcattctt tgttttaaat
    23701 tcatgccctt tcgtgagttt tggtaataaa aatgcttctt tcgttgtgcc gaaaactgta
    23761 acattttctt tgttttttcc tttgattgct ccgctgtaca atccgattgg tgctttctct
    23821 cctccttcaa tgtatttcag atctcctctt gttaattgtg aagctgcaaa tacttgattt
    23881 gcatcctccg acaaaacaat ctcttgtgcg tcccaatcat cgattgcttt tttaaactct
    23941 tctgaaagtc cattcgctag tcctgacaac atgaatacga catacgcaat caagaacata
    24001 ataccgacga tcaagccata tcgtaattta gaatagcgaa tttctttgat agctagaaac
    24061 atttgttttt cctccctatg atagattgat agtgacaaaa tgtcacttgt tgaatagtgt
    24121 aactctaaag tgacaatttg tcacttgtgt tgtttttttc ttatcaataa attgtctaag
    24181 acatctttcg ataaaacctt aacatgagtc ataaaaaatt tatttaagcc ttatttatgc
    24241 tttccatgat aaactaaagt gaccaaatca atgaggtggg aaaatgatta aactattagt
    24301 agtagaagac gataaagtat tatccaataa tataaaagaa atactcgctg caatcggcga
    24361 gataacacaa gtttatgatg gtagtgaagg actgttcgag ttggaaagtg gagtttatga
    24421 tcttgcaatc ttggatttga tgatgccgga aatgaatgga tatgaagtgt tagcaaaaat
    24481 acggaaagaa aaaatacaga ctccagtatt gattttgact gcaaaagata gtttggaaga
    24541 taagattgaa ggatttgaac gaggtgcaga tgattatcta acaaaacctt tctatcgaga
    24601 agaactgatc atgcgcgtga aagcattatt gaaacgctcg ctaggtctct ttgatgaaaa
    24661 tgttctgaag tataaggata tcagttgtga tttaaaaagc aatgaagtct tgtataaaga
    24721 acaagttttg cccatacaag gaaaagagtt tgaattgctc gtttattttt tacaaaataa
    24781 gggaatcatt ttgacaaaag agcagatatt tgaccggatc tggggatttg attctgatac
    24841 gacgattaca gttattgaag tttatatgag caacttacga aaacatctgc gaagtactgg
    24901 attggataaa gaaatcaaaa ccttacgtaa tgtcggttat atactgcaaa gggtgtgatg
    24961 caatgaatgg agatattaca cgaaagcaac gtagtcgctt ttttgcgaca aatgtagcag
    25021 catttgcttt tatctttttt cttttgggat tcattacttt acagatatta aaccaatctg
    25081 catacagaga aacagatctg tcattagaga aaataaattt tgattctcga acagtacaat
    25141 tagagataca aagatatcag caaggcgatc cctttttaaa cccgactcaa acggaacaaa
    25201 acagaacaaa catggaacag ccattaatgg aaccatcaaa tgaccgtttt aacactcaag
    25261 tgatcttgtg gtctaaaaat ggtgagatat tgaataaagc agctattggt gggcgtttca
    25321 accaaatcaa agaattaaaa atggatacga aaaatctgaa taccatccaa aatattgaat
    25381 taaatgaaga cagtggctca tctgccctct ctttccgttc gattacgaaa aaagcggaga
    25441 cgaatcaaga tggcgttgcc tacatccaaa ttttagaaaa tacaaatcaa atcaagaatt
    25501 cattagcgac ttttcgcacg attatgattt tgtgtatgat tgttttttgg attctctcta
    25561 ttggtatcag ttattacttg tctagtctaa gcatgcgccc tattattctt tcttggagaa
    25621 gacaaaaaga atttgttgag aatgcttctc atgaattgcg cacaccgtta acgattattc
    25681 aaaatagttt ggaacatctt tttaccaagc ctaatcatac tattattgaa gaatccgaaa
    25741 gcatcgctca agcattgtca gagacgaggc gcctcactgg attgacttcg gatttgctga
    25801 caatcgctcg gaatgattct gatcagcagc tgctttcaaa gcaaatgatc aatacacaag
    25861 aatatatcga acaacttgtt aaaccatttc aagagatggc catcatagat ggaaaagagt
    25921 ttattctcca taacgatgca acattagaag taccaattga tgaaaaaaaa atccatcaag
    25981 ttttggttat tttgctggat aatgcattaa aatatacgaa tccagaagat aagatcattt
    26041 tggattcatc tgttaaccat aaagaatggc tgattcacgt aaagaatact ggcccttcta
    26101 tcagtgaaga agatcaagca aggatttttg atcgatttta tcgggaagat caatctcggg
    26161 cgaaagagac tggcggatac gggcttggct tggcaattgc aaaacaggta atcgaacagc
    26221 atcatggaca gatttctgta tccaattatc ttccacaagg agtcgatttt aaagtccaat
    26281 tgccgttgaa gcctaaaaaa taatgcttat ccctaaaaaa gggctgtgac aaaaatcttg
    26341 tcacagccct tttttgttgc gaataaacgg tgttccagaa gtagcttctt cggaaataag
    26401 ccgaaatttc tttaagctga ccacttctgt cacaacctct ttagcttacg cttacgattt
    26461 tttattgcgg tcttcaatgt gtacatcacc gcttgtgtca atatccaatt cttctcggct
    26521 aacatcttct gtcacttttt caacatcttc atgttcttct ttatgaatcc caacttcttc
    26581 acgaataact gtatgtttgc ttacatctac ttgctcttct ttgattggga tagtaatcgt
    26641 gtcatcttcc aatttttcgt ctgttccctg tgaagattga tctgttactg gtttgcgttc
    26701 gatgacgatt tcttcacgtt tgaccggtac ttctaccgtt tcagtatcgt tgaccacatg
    26761 tttgtggatg tcgacttctc cagttgtcac atcatgtgta tttacatcta atttttcttc
    26821 ttttagttga attgtatcat catctagatt tggtttgcga tcgatgtctt cagtcttgct
    26881 tgtacccatt gtatcagtct cgccaggtac gtccatcgga tcagttcctg gtgtcatatt
    26941 caatggatcc gttgtatttt gaaagcctgt cgtgccacct acgtccattg gatctgttcc
    27001 agtgccagtt tctaatccag tccccattgt gcttgctggg ctaacagtat cttgtgtatc
    27061 cattgtatct tctgttgttt ctggctgacg atagcctttt actgtgatga caaattttcc
    27121 atcagaaata tctcctctat attgatataa aggatcattt tctggtgtag ccgtctcaga
    27181 atcataggta tcaaaagaaa aagtatcttt tattttttcc cataaagaac ggtcttcttc
    27241 accatccatc cgattttcat ctgtttcaac atctatacca gacaatccgt caaatcctag
    27301 tctagatgct gcttcatcag tagtataaat aacgatatca tctcgttcat acccttcgtt
    27361 acgcaaccgt tcaattactg ataatgcttc ttccctcgta ctatagcttc cgatgaccgt
    27421 taaatttttc tcttccatgt aaattcctcc tagcaaatag atttatgatt ggtatattgt
    27481 tacttataaa tttattctat aggagacgat tgttttctac aaatatttag attggaattt
    27541 gattaaaaca atttaattga aatttgaaaa catttatgtt aatgaaagtc atattctaat
    27601 aaaatgtcat ttgtttctat atgaattttt atgaaaaatt tcatataatt tccactcgtt
    27661 gtgatggttt aatttatcca atccatcaat aagcaaacaa cttatataaa aaaggattaa
    27721 ttctcaatat aattgctcct accatagaat aaatcttcat gtaaagtaat gaagtaccaa
    27781 ctatttctaa tacttcttta agaattatcc caacaatatc gttagacaaa ccattattga
    27841 ataaatggag agccaatcga ttctgaaaaa atgttttcta atttttcgga aataaaagaa
    27901 agagcctcct gccattagaa cgaaccaaat ccatttcatt gctcatgaag taaccacata
    27961 gctaaaaaga ggataaatca attaaaagat caaaagaatg actgcactaa taaaataact
    28021 aaaaatgtat cttcttactt catatctttt agctagtact tagttaaaaa tttgcttcct
    28081 aagatcaaga caaactgtct atcttcattt gatgaaatgc ggtaaaatat agaaaatgaa
    28141 cactattgga gggaatttgt aatggacagc aaaactagaa aacaactgca agaaaagtta
    28201 aagcaacgta cacacttgct cccttccgtc tttcaacagt ttttagaaga aaatcgttct
    28261 tccctttcat taggcagtcg ctatgaatac gcaaaagatt ttcatctgtt tactgattat
    28321 ttgagaaaag tattttctga agaagtggat gatcagctga ttatccattt agaaaaacaa
    28381 gattatcaga atttcttagc taaaatctat cgacatactc gttcgttcca aactacagcg
    28441 aaccaagaaa cggagcaatt gtttgaaaat agctattacg ggatttcaag gaagcaatat
    28501 tcattaaatc attttttacg atttttgtat caaaaaggac tgattgaaga agagatttct
    28561 cttttgggta caagtttacc ggaaacaacc aaagcagctc cgcgatatat cgatgcagaa
    28621 cttttcaaag attttgagca tttgtttatc ccgattgaag gctttcaaac aagcagagaa
    28681 gctagctttg aagaaaagaa tagaccgagg aaccttgcaa ttactgccat tcttctgtat
    28741 tgcggattaa agatccatga agtagtagaa cttaaacgta aagatgtatc tttgaccaag
    28801 cagattctta atctgaatag aaaagaaaac agactgaata aagtaccaat accaaaagaa
    28861 gcgatgccat ttctggagaa ctattttaag ttaacagcac aaaatacgga cgaaaattct
    28921 tttgtttttc gttcctcaca tgatcagcaa atttctcctc ggactattcg ccaaattttg
    28981 agcaaaatta cagtatataa aaacgtatcg ccagaactat gcagaaaaac atatcgttat
    29041 tatgcagaac tatatttaga tgatgctgac gcggtaaatt atttatgtgg taatcgatac
    29101 ctctcatccc attcttttca agatatctgg gaaaagatgg ttgatttttc ttatcacgaa
    29161 ttagcggcat tcgttcgggt ttcttccata taaaacaaat gtatgatctt tttttcacaa
    29221 taaactatgt tattatataa aggattatgt tacgattatc ttgaatttgt atattactta
    29281 acaaaagata atggagtgtg aatgatggag accataacgt attccccttt gaacttattt
    29341 acgaattttc aagaagctgc agctaacttt tccgagaccc cgattatctt tgatgagcca
    29401 ctttcagctt tcccagaatt aggacttgaa acaacttaca aaaaatgctg cgaaagtgtg
    29461 ttgaaacggg cttatcaatt ggctcatctt ggagtgaaat ccggagacaa agttattatt
    29521 tataagagtt ccgcttttga cacatacctt ctagctgttt ctgtgtctta ccttggtgca
    29581 gtgcctgtca tgacttctta tcatctacca acaacaacaa tggaagtatt tatcgatcgt
    29641 ttagaagacc ctttcatttt atttgatgat gagacaaaaa agcgagtgag agaaatttca
    29701 aatggaacaa aatcaaaaca gattcctatt ctttatttaa tggaacaacc tgctttgtct
    29761 gtttctcaat catttttaga caaaaatgaa atttcttata tgacccatac ttctggtaca
    29821 actggtatcc ctaaacttat ttgtcattct gctcattcta tgggatggcg gacgaaatgg
    29881 caaaaaacag ttttcacaaa aatttcggaa aagaaattaa tcgcttttca catctctcca
    29941 gtgcattcca gattcaatat tggtatctct tctttgatgt ccatgggatt tcctatgatg
    30001 cctttagcaa acgcacaaag ttcaaaagtt gttcatatgt tggaagctca ccggccaatt
    30061 gcactagaga cccatccgaa taactttgtt cagtggcgtt ttactgctaa ggagcatcca
    30121 gaagcttttt cgggtatccg atactatcac tccacttttg atgctataaa caaccagaca
    30181 atgaagacat ttttgcgaac gtcgatggca caggatgcgg tatttcttca agtatatggc
    30241 caaagtgaat gcggaccaat gattcttaag gctcatacac tagagagttt gaaaacaagt
    30301 gatgcaagag atatgggcgt tggactggaa gacatgacaa gcgctcggat tacagattca
    30361 gttgggaatg tcctacctga aaacacagat ggtcatatac aattactgtc taaaggacgg
    30421 gctttgactt attacaagga agatgcacgg ttccaggaaa atgtttatgg cgattggtgg
    30481 gatagcggag attacggttt tatggataag catggccacc tatttttgaa agatcggcaa
    30541 gtggatttga tcgaaacgat caatagtaca ttagctattg aagacttttt attagattcg
    30601 ttagattttt tggcagaagt agtgattgta agggataaaa atcattctcc acaaccgatt
    30661 attgctttag ctcctgataa agaaatggat tggaatcgat ggtgggagca agtccatgaa
    30721 cttcctcgct tgaacgtccc tatcatccgt gattttgatg caatcccgcg aacagctaca
    30781 atgaaagtgc aacggcttca aatcgagaaa gaattaaaat cacaaaagtc ctaactattt
    30841 aaggaaagaa agatccattt tggtctttct tttctttttg tttttttaaa ttggatgaga
    30901 taaaaatatg ccaattggct gtttttcttt tttgaaaatt tcgttatact cttattcatg
    30961 gaggaaaatg ttatgaaaag aatcttgaca attggcggtt ctgatccatt tgctggtgga
    31021 ggaatccaaa cagatttaaa aacttttgag aattttggtc tattcggact aagcgccttg
    31081 acttctatag gggcactaga tattaatgag cgatttatgc tggaatctat atctttggaa
    31141 ttgcttaaac gacagttagt ttcgattgat aaaatgactt cattagatgg tatcaaaatt
    31201 gggttattga attcaagtga agcaatcatg gttgttcgag acttcataaa aacaaaacaa
    31261 aatatcccaa tcattttaga ccctgttttg gcattcaaag aaactgaagc tgtgatcaat
    31321 caattgtata tttcgcagct catcgaagaa ctttttccac ttgttacgat gattacgcct
    31381 aatttggcag aagctgcttt actttctggt caagctcttc cctcttcgtt aacagaaatg
    31441 atccatctcg ctaaagaact cactgcttca ggaacaaaaa acattgtgat caaaggcggc
    31501 acaaggatgg ctggagatga agctgtggat cttctctatt caattgatca ttatgaggta
    31561 ttttctcata aaaaaatcga cactacaaca gtaaacgggg ccggttgtgc cttttcttct
    31621 gcaataacag cgaatcttgt gttaggggca gattttacca aagcagtagc agaaagtaaa
    31681 aaatttgttg cccattgtat ttctaatggc gtgctgatga acgatcatac cggaagtgtc
    31741 tggtctggcg gtattcaaaa aggaggaatg agaaatgaaa actaagcaat taacgatcta
    31801 tgctatgctg attgcgttga cagttgccct ttcattaaca attttgatcc ctgtaccggc
    31861 tacgaatgga tttgtgacat tatgcgaggc cgggatctat accgctgctt ttctttatgg
    31921 tccaacgggt ggattagttg ttggtgcttc cagtggtcta ttgatcgatt tgatttcagg
    31981 atatccgcag tgggcagttt tttcattagt gatccacggg ttacaaggat atgttgctgg
    32041 ttctttcagc aaatcttcta ctcgtatgtg gggattaggg cttttattag gaagcttagt
    32101 tatgatcatc ggctatggta tcgccggttg gattttatat gattggccgg ctggagtggc
    32161 ttctatacca ggaaacatct tccaaaatct gattggaatg ggacttgcct ttcctataac
    32221 tgcaagtctt caacgtattc aagcacggaa gcaatattaa ttgaaaaaga aggttttaga
    32281 aaatgaagtt gtcagaaaaa gaattaaaag accaattgac tgaaatagtt aatgacatat
    32341 tggctgaggc acacttgaaa aaaggtgatc tttttgtttt aggatgcagc acaagcgaag
    32401 tcgttggagg acatattgga aaaaattcca gtgcggaagt tggtcaatgg atcatccgta
    32461 cgttaaaaga gttgttggat cctaaagaaa ttgcgctagc tgtccaaggt tgtgaacatt
    32521 tgaaccgagc attagtagta gaacgaacag tggcagaagc aaaaaatttc gaaattgtct
    32581 ctgttgttcc tgcactacat gctggaggtg cttgttctgt tgctgctttt gaccagttca
    32641 atgatcctgt cgaagtggaa cacgtagttg gacaagccgg tatcgatatc ggtgacacat
    32701 caatcggtat gcatatcaag catgtccaag tacctgtcag acctcgtttg aaaacccttg
    32761 gacaagctca cgtgacagcc cttcgctctc gtcctaaata tatcggtggt cctagagcga
    32821 attattgaaa tgagtaattg acagagcaat ctgaaaaact tcctcgcaaa gtccaactaa
    32881 tgaactttaa cgaggaagtt ttacttgttt gttttatata accgagcttc ataaggtgct
    32941 agtatgcctt tagcttcaaa ttctccgcta gaggaatttg acaagagtaa tgtccaggac
    33001 tgatctgctt cttttggaag ttcatagtca gcaagtgatt ctgttaagtt taccataata
    33061 agatattgtt catcttctaa atatctttca tagacataaa gttgtggatg ttcatgaaga
    33121 tattctttat aagaaccgta tatcagacct ttattggttt gtctaatgcg gatcatgttc
    33181 ttatagaatt gcaggaccga ctctggttca tattcttgtt gttctacatt gatcgttttg
    33241 gtatttggat tagtgatcag ccaaggttca tgtgtagaaa aaccagcata ttgttccgaa
    33301 gtccattgca tgggtgtcct gctgttgtct ctcgttgttt cacgaatgat atccaatgct
    33361 tcttctcttg tcttaccttc cgcaagcagc cttttataaa gtcttttcga atctactgca
    33421 tcaacttgat cgatcgattc aaagggcata ttcgtcattc cgatttcctg tccttgataa
    33481 ataaatggcg taccttgcaa aaagaaatac atcatagcga ttgcttttgc agacatagcc
    33541 caaaaatcgg gacgagtatc tccaaacact gaaacggcac gaggaacatc atggttttcc
    33601 atatataaag cgttccatcc gataccatcc aatgaagttt gccaagcgct taatgcatgt
    33661 ttcaatttaa ggacatctaa ttgcccttct ttttcttgct gccagatatg gatatgatca
    33721 aattcgaata tcatatcgaa ataaccgtct ttccctaccc attgtggtcc ttcttctgca
    33781 gtgacaccac ttgcttctcc gacagtcatg atatcgtact cttcaaaaac atgtttcaaa
    33841 tcggtcaaat gttcttcgat tcctgagaca ttttgaaagg gtgagaaagg gttctctgtg
    33901 gcttttactg aatattcatc tttttttaca tgagaaatcg catctaaacg aaatccatct
    33961 atccctttat ccaaccacca tcggatcata ttgaatagtt cttctttcaa tttctcgctt
    34021 tcccaattta agtctggttg ttcttttgca aaaacatgca gataatactg tccagtttca
    34081 tgagaatact cccaagcaga accgccgaaa atcgatgtcc aattattcgg ttctttgcca
    34141 tctaccccgt cgacccaaat gtaataatcg cgatacgggc tttctttaga ttttttcgat
    34201 tcttcaaacc attgatgctg atccgaacta tggttgatga caagatccat aatcactttg
    34261 atccctaatt catgtgcttc ttttagcaat aaatcaaaat cttccatcgt tccgaatctc
    34321 tcttctatat cttgatagtc acttacgtca taaccattat cgacaaatgg agattgatag
    34381 atcggattga tccagataaa gccgatacca agatctttca aataattaag tttttcacgg
    34441 atcccattga tgtctccttg accatcgcca ttgctatctt tgaaactagc aggatagatt
    34501 tgatagccta ctgcttcttt ccaccatttt tgttcttgta tcatatcgtt tcactccttt
    34561 aacggtccct cttgattata accgattcta ttttagaagt atccttgtta ccggtaacta
    34621 gaaacgaaaa gctcaacgaa tctgctaagt gcgttcgttg agctttattt tatcatagat
    34681 agcgggcaat cagttgaatc atttgcttgg gaaattcatt caagtcagta atatctacaa
    34741 aacgactttc accgtagatc gacttgattt cttctttgtc ttggccaata gctgcggaga
    34801 caaataggat tccttgacgt tcatattctt tcaaaacaga ctggatatct tcttttgctt
    34861 ttttgcctgt ataatccggc aatgcttttg gctgaccgtc actaatatta agcaacagtt
    34921 tggttgttgc ggattgtctg tttaattttt ctgctgctaa acgaagtgca gcaccatcac
    34981 gattgttttg ccttggtttc atagtgacta atttttcatt taaccattga aatccgtctt
    35041 caaattcttt ataagaaaac aaagaagtct tttctcttga cgaacggtct gctgtatctc
    35101 cgtaaatcaa caatgggata tcgactttct tagaaaattc ggcaatggca atcgctgctt
    35161 tttttgccgc ttcgatccga tcatcccgta tcattgaccc agattcatcg atccgtacag
    35221 ctaccgctaa agaaggttgc tcatgtggcg ggttcttttt gtcaaaattt ctcaaatcac
    35281 catatgctac tttgcttgca ttgaaccgct gaccttcgta ttttcctttt tggtacgtct
    35341 ctgtttgttc attatccagt aactctaaaa tttgccggct aagtgattct actattggca
    35401 ttacttgcat gtgtagctca cgtgcttccg gcgtttttcc ttggaaagct ggtcggtgaa
    35461 cgatgagacc ttctttttca tgaatcgttt ccttcatgat ttgtcgcgct tctttattca
    35521 gttgcttctt gatttcctta tcatgtgctt ccatgtcaga agcagacatt tcttgagaat
    35581 catctcctgt ttgttgttct ttttgatttt ttccttcgat atcgctactg cgttcttttt
    35641 gcatttgagg aggaatctcg tttttttcta ttgtttcttc ttgtttctct tctccctcat
    35701 ttggttcttc agcagacaac gatttctttt catctaagcg cagaatttct tcagcatttt
    35761 cagtgatgtt tcgttcattt gcttcttcgg cgctaatggt tctttctttt gtatgctcag
    35821 attgaggatg accccatttt tcttttctca atatgtcctg aagttccagt agcaatccac
    35881 tgtcagacaa agcttgttca agaattgcca attcatctga atcagtggat aatttataca
    35941 aaacttttgg ataaatcgac tggagtaaat cttgtccttg cttataggta tttgcccaat
    36001 aaaaataaga acgcattcct gctacacctt tgatggcgtt agcttttgca gtttcatcca
    36061 acaaacggat aatctctgcc atctttaaga gaagttcttg tttttggatc atagttttcg
    36121 ccatcgcacg ttctgccatg acttctaagg caggaagatc cattttttcc gcatgttgca
    36181 tccgatctct taaagattca tttaatgggc gatttccttg gtaatttcga tttgtagtga
    36241 tcacaatgac gcaatctgga tggcgacgaa tgattcctgt cggtaaattc aacatcccat
    36301 ttggttcgag cgctgagtta agtgccacaa gaacagaggc atctcggatg acagtcggct
    36361 cttgaatctc taataaatag cctttttcaa tcgctcgaac gatttcagaa gggtaatagc
    36421 tgtaatggat tgcatctgga taatcagctt cgatcctttg aactagctct gctaattttt
    36481 ctttagcaga aaaaggatca atgccgtaat ggttctggat cagtgtcagt acagcttcaa
    36541 gtgtatctgt ttggtaaata gcttctagta attcttggtc ttgttcctta ttagaatcta
    36601 ctacaggtaa taaggctccg aaaacatctg atttgtccat atctgcaaaa caggtcactt
    36661 ttgtataggg aagttgcaga tcagcagata gtgctttggc taattgtgtc ttccccgacc
    36721 cggcatctcc ttccaaaagt acgttactga ttttcatttc aggatcttgc caattccctt
    36781 tgatttcgga ggcgatccgc cattcttctg cacttgtccg atggcttttc ggtttcttcc
    36841 agatcatttg cttttctagc cgtgaaaagg ttcggttttc tgttagtgag aaattctcca
    36901 tgcttctctt ccccttttga tcatctctgt ctattaatat cctagctcat ctaaaagacg
    36961 ttttaaaata cggaatcgtt ccccaatcag ttctccgtct ttttgtagtg tatcgtaata
    37021 caaaatgatg tcttcatcga tctttggatt tttggtatct acttctaccg tcattcggtt
    37081 cccttgtaat ccaatgatgt ctacgactgg attttctgga tcataaaatt tttcataacg
    37141 ataagcatct tggaagtata aacttccttg cgcagctaag atcgctaaat ctaaaatacg
    37201 tgtgattggt aattcttccg actgtcgtga ccatttttct ccagtatgtc gccatacctt
    37261 gcctgagata tcgacttttc cacgatcatt ccactgagca aggcccagtg aaagcccttt
    37321 tgcatccata tttaatgcat ttcttccatc aactttatca tagtcttcta caacgattac
    37381 tggtttatgt tttaaatttg ttggtatttc cattatttta actcctcatc cttttatttt
    37441 tagtaaataa gtaaattagt agtttactca tttactaaac tatatgcgac attatagagg
    37501 attgaagtga ggattgcaaa gaaaaagagc ttcattgata gaaataaaaa caccatctcg
    37561 ttcttttaca cgctcattag taacatgtag aaagtccaag atgatgttgg aat
//
LOCUS       DAYYEF010000024        36569 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000024 DAYYEF010000000
VERSION     DAYYEF010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.024"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="ACHA1B_001377"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="ACHA1B_001377"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004824 - lysine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006430 - lysyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HFM8702146.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="ACHA1B_001378"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="ACHA1B_001378"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HFM8702147.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="ACHA1B_001379"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="ACHA1B_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0051082 - unfolded protein binding
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HFM8702148.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="ACHA1B_001380"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="ACHA1B_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HFM8702149.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="ACHA1B_001381"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="ACHA1B_001381"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HFM8702150.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="ACHA1B_001382"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="ACHA1B_001382"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HFM8702151.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="ACHA1B_001383"
     CDS             complement(8053..8523)
                     /locus_tag="ACHA1B_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S1 domain-containing RNA-binding protein"
                     /protein_id="HFM8702152.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="ACHA1B_001384"
     CDS             complement(8569..8994)
                     /locus_tag="ACHA1B_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HFM8702153.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="ACHA1B_001385"
     CDS             complement(9061..9330)
                     /locus_tag="ACHA1B_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HFM8702154.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="ACHA1B_001386"
     CDS             complement(9341..10936)
                     /locus_tag="ACHA1B_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HFM8702155.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="ACHA1B_001387"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="ACHA1B_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HFM8702156.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /gene="pth"
                     /locus_tag="ACHA1B_001388"
     CDS             complement(14489..15049)
                     /gene="pth"
                     /locus_tag="ACHA1B_001388"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HFM8702157.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="ACHA1B_001389"
     CDS             15402..16376
                     /locus_tag="ACHA1B_001389"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004459 - L-lactate dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HFM8702158.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="ACHA1B_001390"
     CDS             16546..17946
                     /locus_tag="ACHA1B_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HFM8702159.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="ACHA1B_001391"
     CDS             complement(18024..18746)
                     /locus_tag="ACHA1B_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8702160.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="ACHA1B_001392"
     CDS             complement(18825..19331)
                     /locus_tag="ACHA1B_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFM8702161.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="ACHA1B_001393"
     CDS             19454..21253
                     /locus_tag="ACHA1B_001393"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HFM8702162.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="ACHA1B_001394"
     CDS             complement(21321..22895)
                     /locus_tag="ACHA1B_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NlpC/P60 family protein"
                     /protein_id="HFM8702163.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="ACHA1B_001395"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="ACHA1B_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HFM8702164.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="ACHA1B_001396"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="ACHA1B_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HFM8702165.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="ACHA1B_001397"
     CDS             complement(24672..25310)
                     /locus_tag="ACHA1B_001397"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HFM8702166.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /gene="rpe"
                     /locus_tag="ACHA1B_001398"
     CDS             complement(25311..25961)
                     /gene="rpe"
                     /locus_tag="ACHA1B_001398"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HFM8702167.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="ACHA1B_001399"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="ACHA1B_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HFM8702168.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="ACHA1B_001400"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="ACHA1B_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004672 - protein kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HFM8702169.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="ACHA1B_001401"
     CDS             complement(29104..29844)
                     /locus_tag="ACHA1B_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HFM8702170.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="ACHA1B_001402"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="ACHA1B_001402"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HFM8702171.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /gene="fmt"
                     /locus_tag="ACHA1B_001403"
     CDS             complement(31215..32153)
                     /gene="fmt"
                     /locus_tag="ACHA1B_001403"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0071951 - conversion of methionyl-tRNA to
                     N-formyl-methionyl-tRNA [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HFM8702172.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="ACHA1B_001404"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="ACHA1B_001404"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFM8702173.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="ACHA1B_001405"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="ACHA1B_001405"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HFM8702174.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /gene="rpoZ"
                     /locus_tag="ACHA1B_001406"
     CDS             complement(35313..35618)
                     /gene="rpoZ"
                     /locus_tag="ACHA1B_001406"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFM8702175.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="ACHA1B_001407"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="ACHA1B_001407"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004385 - guanylate kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006163 - purine nucleotide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HFM8702176.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7989 c         6706 g        11988 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaagc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcttg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatcg cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gcaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ccagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttcgtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc taattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gatatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatac
//
LOCUS       DAYYEF010000025        34836 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000025 DAYYEF010000000
VERSION     DAYYEF010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34836
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.025"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..2322)
                     /gene="esp"
                     /locus_tag="ACHA1B_001408"
     CDS             complement(<1..2322)
                     /gene="esp"
                     /locus_tag="ACHA1B_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HFM8702177.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFT"
     gene            complement(2939..3292)
                     /locus_tag="ACHA1B_001409"
     CDS             complement(2939..3292)
                     /locus_tag="ACHA1B_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702178.1"
                     /translation="MSCFVESERLSNGNNSVLNEYDKVVINKVKSLCEEARESISHIN
                     GSNFKQTLFNLIKLDAKISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKL
                     NNYKLIDYKYLSESN"
     gene            complement(3389..4594)
                     /locus_tag="ACHA1B_001410"
     CDS             complement(3389..4594)
                     /locus_tag="ACHA1B_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HFM8702179.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKDFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTGNLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            5288..5674
                     /locus_tag="ACHA1B_001411"
     CDS             5288..5674
                     /locus_tag="ACHA1B_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFM8702180.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            5772..5963
                     /locus_tag="ACHA1B_001412"
     CDS             5772..5963
                     /locus_tag="ACHA1B_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702181.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            6477..6809
                     /locus_tag="ACHA1B_001413"
     CDS             6477..6809
                     /locus_tag="ACHA1B_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM8702182.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            6719..6922
                     /locus_tag="ACHA1B_001414"
     CDS             6719..6922
                     /locus_tag="ACHA1B_001414"
                     /inference="COORDINATES: protein motif:HMM:NF024673.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFM8702183.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            6953..7099
                     /locus_tag="ACHA1B_001415"
     CDS             6953..7099
                     /locus_tag="ACHA1B_001415"
                     /inference="COORDINATES: protein motif:HMM:NF012870.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702184.1"
                     /translation="MTDITYIPCNDGRLYLSTYIDLATRILRYYMVDSHMKKEIVVRP
                     LQIY"
     gene            7106..7261
                     /locus_tag="ACHA1B_001416"
     CDS             7106..7261
                     /locus_tag="ACHA1B_001416"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HFM8702185.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
     gene            7537..8877
                     /locus_tag="ACHA1B_001417"
     CDS             7537..8877
                     /locus_tag="ACHA1B_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFM8702186.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(9118..9525)
                     /locus_tag="ACHA1B_001418"
     CDS             complement(9118..9525)
                     /locus_tag="ACHA1B_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFM8702187.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
     gene            complement(9714..10724)
                     /locus_tag="ACHA1B_001419"
     CDS             complement(9714..10724)
                     /locus_tag="ACHA1B_001419"
                     /inference="COORDINATES: protein motif:HMM:NF014542.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFM8702188.1"
                     /translation="MPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVNVDG
                     VLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGISKPI
                     PIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVVEEE
                     QDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVDLSK
                     ILNTNLFNIDETSYSMGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFAHLT
                     DKNFPGNITRAKGFLWFAQHSDFSTIFETSGSHKSIESLNYWVASLPKIECQMIIQKN
                     PN"
     gene            10850..11068
                     /locus_tag="ACHA1B_001420"
     CDS             10850..11068
                     /locus_tag="ACHA1B_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702189.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            11161..11724
                     /locus_tag="ACHA1B_001421"
     CDS             11161..11724
                     /locus_tag="ACHA1B_001421"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFM8702190.1"
                     /translation="MDFSISFITIYRAICNDLFDTEPLSHGNKGLIRSLHHRGKTRHT
                     KNHVESRGKICLTHSIHGHPKSADDRSDFGHWKADIVAGKTSGTCLVTLTDRKSCFLL
                     AGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITPDRGKEFSNHFAVTEVLNNMPFYFP
                     DPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(11917..12156)
                     /locus_tag="ACHA1B_001422"
     CDS             complement(11917..12156)
                     /locus_tag="ACHA1B_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702191.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(12180..13703)
                     /locus_tag="ACHA1B_001423"
     CDS             complement(12180..13703)
                     /locus_tag="ACHA1B_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HFM8702192.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            complement(13721..13843)
                     /locus_tag="ACHA1B_001424"
     CDS             complement(13721..13843)
                     /locus_tag="ACHA1B_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HFM8702193.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            complement(13873..14856)
                     /locus_tag="ACHA1B_001425"
     CDS             complement(13873..14856)
                     /locus_tag="ACHA1B_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HFM8702194.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(14880..15029)
                     /gene="rpmG"
                     /locus_tag="ACHA1B_001426"
     CDS             complement(14880..15029)
                     /gene="rpmG"
                     /locus_tag="ACHA1B_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFM8702195.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(15050..15427)
                     /locus_tag="ACHA1B_001427"
     CDS             complement(15050..15427)
                     /locus_tag="ACHA1B_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702196.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(15459..15638)
                     /gene="rpmF"
                     /locus_tag="ACHA1B_001428"
     CDS             complement(15459..15638)
                     /gene="rpmF"
                     /locus_tag="ACHA1B_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFM8702197.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(15653..15922)
                     /gene="rpsN"
                     /locus_tag="ACHA1B_001429"
     CDS             complement(15653..15922)
                     /gene="rpsN"
                     /locus_tag="ACHA1B_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFM8702198.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(16445..18211)
                     /locus_tag="ACHA1B_001430"
     CDS             complement(16445..18211)
                     /locus_tag="ACHA1B_001430"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702199.1"
                     /translation="MQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINMVP
                     AFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLRMQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEKFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(18171..19925)
                     /locus_tag="ACHA1B_001431"
     CDS             complement(18171..19925)
                     /locus_tag="ACHA1B_001431"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702200.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(20035..20604)
                     /locus_tag="ACHA1B_001432"
     CDS             complement(20035..20604)
                     /locus_tag="ACHA1B_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005215 - transporter activity [Evidence
                     IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HFM8702201.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(20622..22037)
                     /locus_tag="ACHA1B_001433"
     CDS             complement(20622..22037)
                     /locus_tag="ACHA1B_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702202.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(22048..22716)
                     /locus_tag="ACHA1B_001434"
     CDS             complement(22048..22716)
                     /locus_tag="ACHA1B_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     component T"
                     /protein_id="HFM8702203.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(22847..23431)
                     /locus_tag="ACHA1B_001435"
     CDS             complement(22847..23431)
                     /locus_tag="ACHA1B_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8702204.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(23766..23996)
                     /locus_tag="ACHA1B_001436"
     CDS             complement(23766..23996)
                     /locus_tag="ACHA1B_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HFM8702205.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            complement(24011..24961)
                     /locus_tag="ACHA1B_001437"
     CDS             complement(24011..24961)
                     /locus_tag="ACHA1B_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein"
                     /protein_id="HFM8702206.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(24958..25800)
                     /locus_tag="ACHA1B_001438"
     CDS             complement(24958..25800)
                     /locus_tag="ACHA1B_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease subunit"
                     /protein_id="HFM8702207.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            complement(25933..26658)
                     /locus_tag="ACHA1B_001439"
     CDS             complement(25933..26658)
                     /locus_tag="ACHA1B_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFM8702208.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
     gene            complement(27119..27433)
                     /locus_tag="ACHA1B_001440"
     CDS             complement(27119..27433)
                     /locus_tag="ACHA1B_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HFM8702209.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            complement(27449..29044)
                     /locus_tag="ACHA1B_001441"
     CDS             complement(27449..29044)
                     /locus_tag="ACHA1B_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HFM8702210.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            complement(29067..29957)
                     /gene="iolE"
                     /locus_tag="ACHA1B_001442"
     CDS             complement(29067..29957)
                     /gene="iolE"
                     /locus_tag="ACHA1B_001442"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050114 - myo-inosose-2 dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HFM8702211.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            complement(29974..30999)
                     /gene="iolG"
                     /locus_tag="ACHA1B_001443"
     CDS             complement(29974..30999)
                     /gene="iolG"
                     /locus_tag="ACHA1B_001443"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050112 - inositol 2-dehydrogenase (NAD+)
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HFM8702212.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            complement(31023..32030)
                     /locus_tag="ACHA1B_001444"
     CDS             complement(31023..32030)
                     /locus_tag="ACHA1B_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFM8702213.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            complement(32143..33303)
                     /locus_tag="ACHA1B_001445"
     CDS             complement(32143..33303)
                     /locus_tag="ACHA1B_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HFM8702214.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            complement(33379..34833)
                     /locus_tag="ACHA1B_001446"
     CDS             complement(33379..34833)
                     /locus_tag="ACHA1B_001446"
                     /EC_number="1.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0018478 - malonate-semialdehyde
                     dehydrogenase (acetylating) activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HFM8702215.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
BASE COUNT        10898 a         6940 c         5335 g        11663 t
ORIGIN      
        1 ggtgaaggtc actttgtggt agcctgcagg aatgttttct cctggatttt cataaatatc
       61 tttacttaca gttactgcta aatcggtcgt gcctacagaa ccatcttggt aaacaatttt
      121 aataggaatt gttccagtaa tcggctccga ttctcctaca cctttagctg gagtgaatgt
      181 aacaatacca gtatttgcat caacacttgc attaccgaag tccttattat agacatctaa
      241 aattgaaaag gcatctttag ctaaaggaac atctggttta tcaaatgtag gttttccact
      301 ttgaactgtc gtttctggag ttgttgttat aggtacgtat gttgcatcat tttccatagc
      361 ttgagaagct tttacagcaa actctacatc cacgtcgaaa gttcgatttc cgatcttaac
      421 agttacaata cctttcgtac tatcagtaac gttagaagta tcaggctctg ttttccatga
      481 atactctgca tcttcaggta agtttttatt attccgaatt gattctttag catctggttt
      541 aaatccaact accacggttt gtttatcaac cgcttttggt gattccttaa taacggttga
      601 accttcttct ggtttatcaa aacctggaga aacgatttgg atttttaatt catctttcgc
      661 gattaattta cttgaatcta cacccgtaaa ttcaaattct acagtatctg aaattggagc
      721 cccatctttt tcatttggag cgatagtttt ttctgctaat acagtacctt ctttatcaac
      781 aagttgggct ttgtgacctg ttcccgctaa ctcgtggatg aatactttcc ccttaactgt
      841 tgtgtcaaca tcatatactt cttctaattc aggtttcccg atatatggat tcgtgtctcc
      901 gctctcttct ttatcgtcag ggtttccatc accatcaata tcttgcaaat aataataacc
      961 tgttccataa gtgttctgga ttaatttttt attcgtatcc gacaaccaag aatcaaagat
     1021 gaaatcttca ccaaatggtt tattttcttc aacttgtgct gttgctttca tatcttctaa
     1081 gatttcatct aatggcttag tcaattgtaa aacatatcga ataacgactg gacgtggact
     1141 tgcattagca aaatcaataa gtttggtaag atcattatca gtaattgaac ctacaccata
     1201 attttcatga tctttgcgcc gttcaattgc taaatcagcc acttttttcc ctgattcaaa
     1261 agaaacatca tatgttactt tgtcagcctg aaccatgtgc atctgtatac ccgctacata
     1321 tggaactaat cgttcatcaa ttttgtaatt agcataccaa ggcgtgccct ttgcggaagc
     1381 tgaatatgag aaattataat ttttcgttaa cttatgatct aagattatag ctccattagc
     1441 acctgtggat cctgaaccat cttttgtttg agtattaggt tcctcatatt ttgcacttac
     1501 tgatccatgt ttaaactggt caggattatt ttcagataca tctaagctat tatagaaatc
     1561 atctgaatct gttaaaaagt agcccgtact atcaatacct ggtacaattt tatcatcgtc
     1621 ttgatgactt accaagtaga ttcgatacat taaacgatcg gtcttgagat tgtctatgcc
     1681 tatctcttta aaaatttcat ctaagctctt ttcaaacgta attaccccat taggagcagt
     1741 ttgtgtatca gttgtttcag ccccagcaaa taatccatca cttgcacgaa tataattgac
     1801 cttccaaata tttgtaggtc tacccagcga atcattaatt cttacaaagg tccgtctaga
     1861 agatccaatt cctttctttg gatcgacctg aattttttct acatatttag ctaatcgttc
     1921 atctaattga agacggattt cccagttttt agttgatgct gcaatattat gttttccgta
     1981 aacttcaaat ccaattgtat tgccttttag tgtgtctcca gttagttctt gaggactaaa
     2041 ttgtaaatcc gaaaagttat aatttttcgt ataaccagga ttctcctgaa aagtattccc
     2101 cgaagctact ttgtcaccta cttgtacgga gcttatcgct gtttcaagtg gggtgcttgg
     2161 agaaatttca tcttgtgctt gaactagttc agttgttccc aagacaagac caacaccaac
     2221 caaaacagat gcaaccccaa cacttaattt tttgatactg tacttcaata ctcgtttctt
     2281 tgttttttct agaaatactc tcttattatt cttgctaacc attattcaaa tcaactccct
     2341 taatagttat tttcttagta agaataaaag ataaatctga tacgtattat tcacagaata
     2401 ggaatcttac taaacttatg ttaactagtt tacttaaaga atttcatgca cattacaaca
     2461 aaaaaagtac atttcttcat gtttttttcg gatatttgtg ctttttaacc attcagcagc
     2521 tgaaaacata taaaaagata tgtatgtatt ctttctgaaa ttaagttcat ttctatgcga
     2581 tgaagcatgt tttcaaaata ttactctttc ttagattaaa cttcagagta ttcaaatagc
     2641 ggaataagga gccttatccc gcattactga atgagactgt gacataagta aaaaggtgac
     2701 ttcaaattcc ttcttcggaa tttgaaatca ccttctttat aattataaag tatcggtttc
     2761 acagcattcc tgaatgattc ctagaatctt aaacgaatga ttggagttat caacattttt
     2821 tcactcgttt ttagcgaaac aaaaaatgac atttgtcaca gcctcattaa attattgatt
     2881 ctttttcttt ataattgaat tgtccatatt taaagtgtct agtactctac atgaataatt
     2941 aattgctttc actcaaatac ttataatcta ttaacttgta gttgtttaac ttttctgaaa
     3001 aagttagacc cacgtaataa tcttcccagc tttctctttc aattaactga tccaattttt
     3061 gataatccat aaattcatca tgtattaaaa agaataaata acttgatatt ttagcatcta
     3121 gcttaatcag attaaataat gtttgcttaa aattgctacc attaatatga ctgatagatt
     3181 ctctagcttc ttcacataaa ctttttactt tattaattac tactttgtca tattcattta
     3241 acacactatt attaccatta cttagacgct cagattctac gaaacaactc aaatcagaaa
     3301 tttcccaaaa aattttttgt taaaatccaa tttcctcaac tcctccaaac tacgtaaatg
     3361 atatagtctc ataataaaat aaaacctctc agctaatgtt gttgaaatta tccactaaac
     3421 ctaattgata ttgcttagga gatacacctg cgtacttttt gaatactctc gaaaagtgtg
     3481 aagaatctga aaatcctaaa cctaaagaaa cttcactgat agtatggttt gatttcaaca
     3541 ttattttagc cgtagaaatt tttcgcttag agatataatt ataaatcgta atatgcattt
     3601 cattcttaaa gctttctctt aatttagttt cacttacaga aaaataatta gctatttcct
     3661 ttacagtaat tcttttatag atatttaagc cgatgaattg aacgacagaa gaaattaagg
     3721 gagaaagatg ctctatctta gtttttccga tttccttagt ataataaaca atcccagaat
     3781 ccctcacttt taagacctca ggtaacgata cagctaattc gttttcttgt atcaaagcat
     3841 ctctactttg atacgcttct attatatcca ttcctaatgt tatagacgtt tgtgctaact
     3901 tttcaaaaac aatgatagaa taattttttt cagaccgaat cgtatctcca ctaacacttg
     3961 gaattattcc attactcaga ttaaaaacca tgttttctaa atttcgaata tctccatttt
     4021 taacatattc cagtatttta ttttcataaa gaaacagata tatttctgga tcgtaatttt
     4081 gtgataacag attatctatt ttgatttgct cgatagtttt acttagattt cctgtatatt
     4141 caattaacgg ttcatggaat agatcttcta tttttccagt aaaaaaataa tgaactaaaa
     4201 tcagaatatc tcgaatgtct cctaaagaat acaaagtcaa attttgcaat gaattataga
     4261 gtcgttctct atcagccatt gcaacattca aattgttcat ttttagttta aaaaaatctt
     4321 tatcaatatt atttgctcta aatggaccaa ataagtaata tctggtttta aacatgtata
     4381 gaagaaacat ctcattaaaa tcaccagtaa agaaatggaa atctttagtt tttttaatat
     4441 tatcagttag taacttttta taatcataaa aaaaataagt agttctatct gagcgatact
     4501 cttttataat actgaattcg gaattaaaaa ccacgatagg taactttaaa caaacatgaa
     4561 gagactttaa taagacttct ttatctgaaa acacttttgt ttctctcttt cctttctaca
     4621 tcattaaata gtattttata cgttatctaa aatactattc ctctgtcaaa ataagctaac
     4681 ttacttcatt ataaaatatc cacttatcgc tttcatgtat attccaccgt aaaaagtaca
     4741 ttttatcacc gagaactcat catttttcat catgatgaat actatttaca tatatctagt
     4801 tcaaagacaa taattattat gatccgttat tatctaagca ctatacagat aataggaatt
     4861 tttcgtttct aaatactcca atttgggaat ccaataaaaa ttttcgttca aatacgtgtc
     4921 tattcgaact cttttctagt tgttaattat gaagggggaa gaaataaaaa atacaatcta
     4981 tacacgaata agaatattat ccaaaaggag gttttagaaa agatttatta tacgtaaaaa
     5041 gctcaagaca ttttcttagc cataaggaca tgtttgatat ttaagaagat atatgaattt
     5101 tcttttctaa gtataaagat aactatccat tatcaactaa aaaaacattt ttgaaaataa
     5161 acatcagcag tcctatcaat gcatgtgagc ttatagaagt tattcgcagc gcagcataat
     5221 tgcattagct tcttttcgtg ttttttgcct cttttccctt taaatcttaa tggaggaggt
     5281 gtgcaatatg tcagataacg acgaacgcgt aaatgcccag ttgattcgat tctttgaaaa
     5341 ggtcattttg aacaccgcta atacttatta taaaaaacaa gaagaaattc aaaaacatga
     5401 acaacttgat caactcccac catatttgtt tactaaagat actataaaat ttaaacaacc
     5461 gattaatgtt ttaaatgtga ctctccttgt tgaagatata aaattagcaa aaatccttcc
     5521 tttgttgaaa gaacctgaac aaatttttct tatcgaaaaa tttatcttta ataaaactga
     5581 taaagaaatt ggaaaggttc tgggtattac aagacagggt gcgacaaatt taaaacatcg
     5641 actttacaaa aaaattcaaa aaatgctggt ttaatatctg cataataact aattttgtat
     5701 gcttctttgc tcgtcctcct ccttccccaa aaaataaata gattataagt tcatgggaag
     5761 aaggtaaatt tatgaatact ttaaaagaag atttcatttt agcaaagaat ggaaatgaag
     5821 aagcagttgt ggccattctc aaaagattta gcgctttggt ccataagcaa tcctggagaa
     5881 ctggaaaata tgatcaagat tgttatcaag aatgtatgct tgcaatatat ctagctatct
     5941 cgaaattcga aattaaagaa taactcaact aagggagtct gtgacataag taaaaagata
     6001 gtttcaaatt tcgaacaata aatttgaagc catcttcttt ataattataa agtatcgatt
     6061 ttacagcgtt ctataatgat tcatagaatc taaaacgaat gattttaatt attaacgttt
     6121 tttaattcgt ttttagctta aaaataactt ttgtcacagt ctcactccta aaattacttt
     6181 atttacgtac gaagtgggca ggaggtcgaa tccagaactg ggccatggta cttcaacgag
     6241 gacttctcct ctagaattga aaagcatgcg atttaccttc cgtaacgacg gtagatttat
     6301 tcaactatgt gtccaatcaa aatttgtctg atttcaaaaa tagtcaagag aattttggtt
     6361 gttaaaaact cttatctatc aacttccaca gtttagttga caaaccctga tactaagttg
     6421 ggctatgata cacttttctt gactatcagt tacgttaccg gaaggaatga actctattga
     6481 aaaaaacata tgatcgtaaa tttaaactaa agatttcaca ggatatcctt gagaaaaaag
     6541 taactaccaa gaaaattgct gaagaataca atatctctcg tccaacaatt tcccgatggg
     6601 tttcagaata tcgtcgatac gggaaaaatg cttttgctgg acaaggaaaa agattacctg
     6661 ataaagcaga tttctacatt cttgaacagg aaaataaacg actaaaagag gaagacgagt
     6721 gttctacgaa cacaaagatc gatacggatc tccagggatc actcaaaaac tttacgatga
     6781 aggaatcgaa atcaataaac gtgttgtagc tgttcttatg cgtgaaatga atttatgcac
     6841 aagaggattt catcgacgca aatcttctca tggtagagaa aaaacaatca aagaaatggt
     6901 aaaaaaaatg ttgaatcgat aatttgaaca gaaccaaatt gatgctgttt gggtgacgga
     6961 tattacttac attccatgta atgacggtcg cctctatttg tccacctata ttgacttagc
     7021 aactcgtatt ctacgttact atatggtgga ttcacacatg aaaaaagaga ttgtcgtccg
     7081 tccattacaa atttattaag gagaattgcc tacggtaatt cattccgata gaggtagcca
     7141 gcatcggtct tttatttatc aagagctgtt gaccgaccac cacatcacac attcaatgag
     7201 ccaaactggg actcctgttg acaatgcagt aattgaagcg tttcatcgat caatcaaatg
     7261 agaattaatc gactccaaca aatataaaag taaaatagag atgaaggtgt taatccaaga
     7321 ttatttagaa gactactacc caaacaaaag aatccataca aaatttatga tgactccttg
     7381 acaatttgaa gcgaagaaaa taagggatct ataatatcta gtgttggtga cgccttctgt
     7441 tgccaatact ttttcttttt tctaataaac gcaaacagac accttgaaat cctttagaat
     7501 aaagtcgacg aaaaccattc aaaggagtgt ttcaagatgt cctattcaga gtttaccaaa
     7561 gagttactag atattctaga cctaaatctt acctttcatg aagatgcctt tcgcaaagag
     7621 cgcattaatg acgaaacatg ttttgttttt gatggcacat tgacctatca accagaggaa
     7681 tgcttccatt gccactatca aaataagcaa acgatcatta aatggggctg gaaaaaagta
     7741 tccatcttat tgaatgatgt cagtaactac aagaccattg tgcggattaa caaacagcgc
     7801 ttcaaatgta aacactgtgg aaagactttt ttagcagaag attcagttag cgatcgtcgc
     7861 tgctccattg cccgcagagt caaacaagcc attcttgagc tattaagtga gcctatttct
     7921 atgtctttga ttgcacgtat gaagcacatt tctccgacca ctgtcattcg aatacttcgc
     7981 agccttcggc ctaaaaccgt ttctttgaac cagccgttac cagaagtggt gtgtttcgat
     8041 gaattcaaat cggtgaaaaa cgtctcggga gccatgagct ttgtcatgat ggacggcaag
     8101 acccatcaac tgattgatat tgtggaaaat cggcaactca atcctttacg cgactatttc
     8161 ttgcgctacc ctagaaaagt ccgtgaacaa gtacgtctag tggtttcaga tttctataca
     8221 ccctatcgca cattggtgaa agagtgtttt ccgaatgccc gaatcgtcgc cgatcgcttt
     8281 catattagcc aacacatcgg tcgggccttt accaaccacc gaattcaagt aatgaagacc
     8341 tttaaaaaag gggatcgtcg gtcgaagcac ttaaagaaat actggagact acttcaaaag
     8401 aatgcgtggg aattgaatgg tcagcatcgc tactggcgtc cgtcatttcg agatcatctg
     8461 acagaagcgg agatagtcga tcggctatta tattatgatg actccttaaa gcgaggctac
     8521 gaagtctacc aggtttttct ttccgctatc agaagacaag atgttcctga attcgtcgcg
     8581 ctcctaaaag aagactacaa ggagttgcca gagcactatc aaccagtgtt cacgaccttc
     8641 aagaaatatc gaacagaaat caaacgagcg ttgcgagttc cctattccaa cggccctata
     8701 gaatgtttga acaaccatat caaagtacta aaacgaattg cctatggctt tagaaacttt
     8761 caaaactacc gagaacgaat ctttttatat cgaggaaaat atttcaagaa aactaagaac
     8821 actacccaac tgactaaagc cagaacaaca acacggctag acaagatagc tgtctagccg
     8881 tgtgagtatc tcgattattc tattgaattt cttcaccaac actcattgac gaagagccaa
     8941 aataagtaat ctaaccgact gttaactaaa ccattgcagg tcccgttaaa gatacttgtg
     9001 cctgttgtca ccgcttcttt ttcttgtcca caagcgctta acacacttaa taaagcccct
     9061 gctattatta ataataatat ctttttctta ttaaaaacct cctcatctat ttccagatta
     9121 gtaaatgtag taatctttgc tttctttttt ctcaatacta ataactaact tatggggtaa
     9181 acaaatactc gtttgaccgg gttttgagat ccatccagtt ctaaccgcga tttgatcagg
     9241 actattatct tctttaactc gaattcttcc atctttaatc tcaacaatat tatattgtcc
     9301 cttcgcagga tgataattca cgagtttatg attgatctta tccaaatcga agcgatccat
     9361 ttccttgcca tcaatttgaa cgatggcata tttgatagca tcttcagttg tttcattctc
     9421 cttttctata gagaatacaa ataagggaat aaaagaggga ataatcaaaa tgccaataat
     9481 tatgacatcg cctatcttga caccagcttt tcttaaaaat ttcattaacg atatctggct
     9541 aaacatatta gaatttttcc atggaaatgg tgaaattttt cggaaattat ctgcattaag
     9601 agaatcagtt aaacaaccct caagttgttc cttaatacat tgttgatcca tcttcatacc
     9661 aataaaaact agtttattaa tgcgttcacc aaacaacgga tgccaggctt ccttcaattc
     9721 gggttttttt gtataatcat ttgacactca attttaggta aactagctac ccaataattt
     9781 aatgattcaa tacttttatg gctacccgat gtttcaaaga tcgtcgaaaa atcactatgt
     9841 tgggcaaacc aaagaaaccc ttttgctctt gtaatattgc caggaaaatt tttatccgta
     9901 agatgggcaa atttttgtgc gtcaaggagt aaccgatttc gatagataaa acttgagata
     9961 ccatattctt ctgtttcagg aatatgattt tgatagccaa gctctaactc tttgaaccag
    10021 cccattgaat aggaagtctc atctatatta aaaagatttg tatttagaat tttcgataag
    10081 tctacttcac ctttaattgt cctaattatt ttggcattgg actgtaactt agcaattaga
    10141 ccgttaattt tgtaaatcgt cttggttgac actaagtcac tattatttaa aagtaatatg
    10201 ttacaacact cgaattgatc aattaacaag ccacgaatat cctgttcttc ttcaactaca
    10261 ttaccttcag cttttctttc ctgaatcttt tcacccgttt cgaaattatc ccaaaaacgt
    10321 tttacatcca ctactataat aatggcacca atctctaatc gttgggtcaa atcaatgtct
    10381 aaagggtttt tagctaatat aattgcttga ataattggaa ttggtttgct gattcctgaa
    10441 gcttcaataa caatttgatt caagtcagaa aattgcacta attgatctag ttcaacaatc
    10501 aaatcttcgc gtaatgtaca acaaatgcat ccattcggca tcgaaacaag tttttctcca
    10561 gttcttttaa aacctttctt gtcgactaat accccatcaa catttacttc ccctatgtca
    10621 tttacaatga cagcaatttc ctttccgtga tcaccgtaca gaatatgatt tagaagtatc
    10681 gtttttcctg aaccaagata gccagttaag attgtaatag gtattttttc atagggaacc
    10741 tctttctata ccttgaattt acactttaag tgcaacacat aaaaatgagt cataatcgat
    10801 atccaactag tataagtttg tcgagaacac tcctagaagg aaaataatta tgagccagta
    10861 ttgtcatctt actatactca aacgagaaag aatctttctg cttcacgaag aaggattttc
    10921 tattagtata attggcaacg acattcagca tagcccgttt actattttac atgaactgag
    10981 aagaaacaag aaaaaaacta atcaccttcc aaagcggaaa aaaattatgc ttatcgaaga
    11041 aaaaaatgcg gacgttatca cattctaaat gatccgtgag tttggtcaat tgttcgtcat
    11101 ttatttgtcg attttcagtg gtcgccagag aaaatctcga atcgtttgaa gcatgaacat
    11161 atggactttt caattagttt tatcacgatc taccgtgcaa tttgcaatga tcttttcgat
    11221 acagaacccc tctcacacgg caataaaggc ctgatccgtt cattgcacca tcgaggaaaa
    11281 acaagacata caaaaaatca tgtcgagtct cgtgggaaga tttgccttac tcattcgatc
    11341 catggccatc caaaatccgc agatgataga agtgattttg gtcattggaa agccgatatt
    11401 gtagctggca aaactagtgg tacttgttta gtgactttga cagacagaaa atcatgcttc
    11461 cttttagcag gaaagaaggt ccccagaaag aaagccgctt atgtgagcga gaaaatgatt
    11521 gaacttttaa gcagtattcc aaatgaggcg gtcaaaacga tcactccaga tagaggaaaa
    11581 gaattctcca atcatttcgc agttacagaa gtattgaata atatgccctt ttattttcca
    11641 gatcctcatg cccttggcaa caatgaacaa attaaaatac gaatagactc attcgagaat
    11701 acttgccaaa atcgaaagag atagctacgg tagataactc aacgataaat cagatgattg
    11761 aaaaactgaa taacagacct agaaagtgtt tagattggag aacaccttat gaagtcttct
    11821 ttgataaagt gttgcgcttg atttgacaat tcaagaaata ataaaaagca gatcaaatcc
    11881 aaataaggga aaaatgatct actctggtat tatcaattaa ttggccaagc tattatgccg
    11941 ttttgctaaa cgtctacttc ttccagtatt gaccttgata aaacaacaat caggatcccg
    12001 ttttaatact ctatgaactg tgtcaatact aacatgtaaa gttgcagcaa tatcagctaa
    12061 tgtactccca tttaatctca tttgctttgc aaattgataa cgccgataag catcaatatt
    12121 cttggaatcc atagacaata atacttttct taccatgtat ttcctccaaa gattggattt
    12181 taatgggcca tcatttcttg agcaatctca tgctcagata atgaagctgg atagaaagta
    12241 ggccaattat gcatttcatt ataaagtttt tcttgacttt ctccaccaaa gaaaatatgg
    12301 aaatgctctg ccttacttgg tgcaattcca tgatcgctaa attgaatata tttaaaacga
    12361 ccagcacctg catcatcagt ttcaaaatta aaacgaacac cacggtttcc tttttcataa
    12421 ttcaaaattt tgtatccaac atatttgtat gtgtattgat gatgttcacc gttgactaca
    12481 aaatcaatgg tgttgtcttt aatgttgata gtatcaatat ctgtcttata gccagtagta
    12541 taataatctt tgtactcggc agctgtcatg tctttattga gttttgcttt gtaatcgaaa
    12601 acttcatcca aaattccatc ttttaacaac ggataaacag attgccattc gcctgtataa
    12661 tcactcaatt cgcgatcctt cacatcggca tctttaaagt acccattagc aactgtcttt
    12721 tcatccttcg cttctttttc tggaactacc tcttcaccag caaccatagt tgttttctct
    12781 aacgctttta gattgtcttc cattactgaa acataatctt caccattatc catttgttct
    12841 tttgtaagac tttcaagagg attcaatact tccaatttta tcccagcttc attggccaaa
    12901 gtttttgcga ttttatcatt agcattcttt tcaaagtaaa tataattgat cttatttttt
    12961 ttaacatact cttttaattc agctaatcga ccagaagatg gctcttcttc aggacttagt
    13021 ccagcaatag gaacttgtat caatccataa tccaaagcta aatatccaaa ggctgcatgt
    13081 tgtgtcacaa aacttttttg tttcgcttct ttaagactag tggtatagtc agcatccaac
    13141 cgtttcagtt tagtcaaata cttttcagca tttgtctcaa atacttttgc ttttttcgga
    13201 tacaatttaa ctaactgatc cttgatattt gaaacttcct taattgccat tttgggtgaa
    13261 acccacgtat gaggatctag ttcatgatgg tgatcttctt ctccgtgatc atgatcttct
    13321 tcttcactac ctggcaataa aatcatgtct tttgttcctt ctactacatt aggcccagct
    13381 ttcttccaac tttctttagc ttttggtacc catgattcca tgttttcgtt atgatataca
    13441 aaaacatcag catcatgagc ttttgccata tccttagctg agggctcata gtcatgaggt
    13501 tctgatcccg ctggaaccat taaatccacg ttcgcttcat cgccgacgat gtttttggtg
    13561 aaatcataca ttggatagaa tgttgttaca atttctaatt ttccatcttt atcattcgat
    13621 acttttgcat cattagtgct ggagcaagct cccaataatc ctagagctgc tatcccaata
    13681 agtcctacac tgattttctt cattcttttt ccttccttaa ttatgctaat ttcttcattt
    13741 tattttgttt atgttctttg ataattttta atgccctttt tctagttttg atattcgggc
    13801 ttttaagtcg tcgatatgca ctagatatat ccgttttctc cattagaaat tacccctaat
    13861 caatacttat cattatttgc tttccgccag taatttatca aaactctgtt tgatcctttc
    13921 ttcatccaac atttttccaa ttagaataat agtggtttgg tctttttgtc gagtggtgta
    13981 ttgaaaatta acctgttcgt ttaccccttg tatggcaact ataaaatctt gatcttgcaa
    14041 agcaatcaat cctttaaaac gatacaggct cccttggttg gttaaaatca gccggtcaat
    14101 taattggaat aaaaaatctt tttttatgtc ttgatctgaa gttaagagaa ttgatttaaa
    14161 ctcatgttct tgatgatgtt gatgatagtg tttgccatta tagtgatttt ctgatgaatc
    14221 actttcaaaa actaagggat gattgaattt ttccaaatta taaaaatcct ttttttgaat
    14281 cgtttcacta tgtgtgaaca ttcgaatatc ggataaaggg ttaatacttt tgatttctct
    14341 ctgtaatttt tttagtgcag ataaattcaa gttttgtttt ctagacacaa aaatgcgatc
    14401 tgctatgaca agttgcttaa gggcttgtgg ttctctttca ataagttcaa aactgtcact
    14461 atcaataaca gtcaataaac tatcgatata tactcttcct cttagttgag gcgctgttaa
    14521 aagtgtttga atgattggtt ggggatctgc tatacctgta gtttcaatga tgatttgtga
    14581 aattggttgt tgatgttctt ctattgtttc cagtaaagaa atcaatattg ctaataaatc
    14641 actgcgaaga ctgcaacaca tacatccatt atttagttgt aacacccgtt cctcgctatg
    14701 aactaataat ttgtgatcaa tcccaacttc accaaactca ttttcaatta taataatttc
    14761 ttccctgggg tagggtgaga cttgcaaggc ttgattgatt agcgttgttt ttccagcccc
    14821 taaaaaccca gaaacgattg taactggtat gcccattttg tcaccttttt accacttagc
    14881 tatttcactt ctttgaaaat tgcccgtctg cgcaattttg gcgaatactt ttttaattct
    14941 aaccgttcag ggttattccg tttatttttg ctggtgagat acagacgttc tccagtttcg
    15001 acacattcca aaataatatt ttgacgcata aatcttcctc cttcaatact tatcgatctt
    15061 caagatatgc ttgaatttgt tgtgcatctt caaaagttaa ctcgccagat tccaattgtg
    15121 aaactaaatt ttctttcata tcaacaggta tctcccaata accatcaata cattgaaata
    15181 actcctcgtc atactcttca aaaattggat agattcttaa aaaatcatca aatgataagc
    15241 cttggtcctc atagtaatct ttgactaatc cattttcaat tgcctgttgg gtcggtaaac
    15301 ccgtttcagt aataattcct ctctctacca tcgaacgata aaaagtgcat ttatctagcg
    15361 attgctgggt cgtttcaaga taatacttta atccttcttc aactaaaggt gggtaaataa
    15421 tttccatttt gattccctcc taaaagttat atattaaact attttgaagc tcctttaatt
    15481 actttctttc cattatagta cccttttaaa gatacatgat ggctacgtct ataatcacca
    15541 ttcgcttcgt caaatgaaat ttctggtttt actacagttt gatgagttct tcttaaccgt
    15601 ttcttcgcct tagatgtttt tcttgctggt actgccatga tatttcctcc ttttaccaac
    15661 ttgctttttt tactccagga atcaaccctt gatgggcaag ttctctaaac ttaatacggg
    15721 acataccgaa ctttcgcata taccctcttg gacgaccatc cgtctgatca cgaagcctca
    15781 gacgattcgg atttgaatct cttggcaatt tagcgagagc ggtgcgatct cctgcggctt
    15841 ttaattcctg acgtttatct gcgtactttt caatcatcgc catttgtttc tttgctttag
    15901 caattttcga cttttttgcc atataccttt atactccttt tattttgatt tagacatctc
    15961 aaatcgtaat cgttacgttt tgacactgat actttaccaa caagagttgc tcttgtcaac
    16021 aataaataac atgaaataaa actcatatga atagataact atttgaaaac gaatttatcg
    16081 gtacatagag ataatcaaat catttaaaag aatatgcagt ttaagctctg aaaaataaga
    16141 attcactttt attagtccaa tcaaacacaa ataccgtttt aagtagcttt tcctctactt
    16201 aaaacggcaa tatgaaagaa actataactt tttattcaat cttttatgtt taactggttt
    16261 atcgccaatt ttttaaaact ttgattattc cttatattat aagaatagac attaagtgaa
    16321 ctaattcaat catactgatt ctttcgtgta ttcaaaatta gatgctgttt aataaaatta
    16381 ttctttttga aaaagaatta taactatatc ccaaaaattg taggttaatt taaagcctat
    16441 ttcatcatcg tgattgagct tctttttcat agacgaattt ctcagatagt ttagttttct
    16501 ttatgagatt tttgtatatt tctgaccttc gatacaactc actatgagta ccttgatcaa
    16561 ctatttttcc ttgatccatc actacaattt tatttacctt ttcaatagac ttcaagcgat
    16621 gcgatataat tagtactgtc ttatcttgta ttaaacgatt taaactttcc tgaatacgtt
    16681 tttcattttc cgcatctaaa ctggcagtaa tttcatctaa aattaaaatt ggcgcatttt
    16741 tcaaaaaagc ccgtgctatg gataggcgtt gtcgctctcc tccagaaagt gaacttccgt
    16801 tttctccgac caatgtatga taaccgtcag gtagtttttc aataaagtct tcgcagttag
    16861 ctaaacgagc tgcttttttc acttcctcat ctgacgcttg actatttcca atacgtatat
    16921 tttccaaaat acttgtatta aacaaagtta cctcttgaaa aacaatagcg attttgctaa
    16981 acaaagaagc tggagataca cgtttaatat catacccatc aattaaaata cagccttcat
    17041 cataatcata cagtctagac actaatttca agatactagt tttcccggaa ccactagcac
    17101 ctactaacgc agtcacttct ccttgtttag ccgtaaaaga gatatgatct aaaattgggg
    17161 tattgttatc atatgagaaa gagacatctc gcaactcaat gtcaaaagat ttcagaggac
    17221 tatctgatcc ctcttggata ctggtttcct tcatagctct aattcgctgt attttaggag
    17281 ctaaataaaa tatttcaagc actgcttctt tcatagaatc gaaggaatcc tttattttta
    17341 ttgcggctag taagtaacca acgacgtaga gtatagtcac ttcacccgtt aacagtaagt
    17401 gaacacctac tagaatgact actgctaaac taacatatga gaaaatagag gataaggcca
    17461 tgactgaaaa agtacttaat tctaccttta aatgaatcct ttcactctct tccatttttt
    17521 tgaaaagtct gtcttgaact tttttagata gattaaagct attaatctct tgctgcaatt
    17581 ctatagtttc ttgaaatttt tccgagtttt ctctcaaagt atcgtaatat ttagtattgg
    17641 ctttcgtttg ggatttcttt gataacaaga ttaagacaaa actaaataac gttggcaaaa
    17701 taacagctaa tcccattttg acattaccaa ccaaaagcat cactgaaata aaagggaaaa
    17761 acagagccat accgccggct ttaggtattg catgactcat cgcatgctca ataccttcaa
    17821 cgtcagacat gatagtttga gataaatctg ataaattatg ttttgaaaaa taggataatg
    17881 gtaaatttga caaatcgtct gcaatttgca ttcttaaatg cgcactttct ttataagtac
    17941 tattatataa gttttcatac tccctatcta acaaccaata catgaaaagc aaagtaacga
    18001 acgatactgt aaaataaagc caaggcggct ttacattttc taaaactaat tcgtctatca
    18061 gcatcattat aatgaatgct ggtaccatat taatgcagta tacaaaaaag ctagaaatag
    18121 atgctttaac caaatcttct gcgccctgat tagttaaagc gaatttgttt ttataaaaac
    18181 ttttcattgt caagcctcca atcatttgca ttctcataat tagtgaccaa ttgtttatac
    18241 acttgatgtt tagccattaa ttcattatga tttccacgtt ctactatttt cccttctgac
    18301 aagacaagaa tttcatctac agatttaatg ctggataatc gatgagctat cataataact
    18361 gttttttctt tcatcagatg ttgaaaagcc ttttgtagtt catactcatt atctggatca
    18421 atagatgcac tggcttcatc cataataaca atctttgcat cttttaaaat tgctctggca
    18481 atagctatac gttgtttttc tcctcctgac agataaactc ctttactacc aattaaggta
    18541 tgctctcttt cgggaaattt ttctaaaatc gattcgcaac cggctaatct tagcgcgtca
    18601 aatactttac ttgctggcgc ttgaggattt gctatagaaa cgttatcgta aatactctga
    18661 ttgaatagtt tcgtatcttg aaagacaaaa gcaattgtgt taataattgt gtcttttgaa
    18721 tagtgattta aaggcttacc accaatttta atctgtccct tatccacatt gtagaaacct
    18781 gaaattagtt tagctatcgt actctttccg cttcctgatt ttcctactaa tgcataaatt
    18841 cttttttgtt ctaaaactaa gttgaaattt tctaaaacac actcttcttt gtatgaaaag
    18901 ctgacatttt caaatgcaat gtcacaattt ttaatctgtg tctcgttccc atattttagt
    18961 tggtcttgct tcatttctaa ataaagggag tctagtgttt cgactgcata tcttgcttca
    19021 aacaagtgca tacttacata cattattctc atgaaagaaa caaaaataat tccacttaaa
    19081 aaaaacaaca tcaacaagtc aacagctaat atcttgggag tggtaagaga agttataaaa
    19141 aaggttatag gaactatcaa aatgcaaact atgccaaaaa atagccattg aaaaagaaca
    19201 aaaggtgttt tcccactcaa agaatactta tatgcaaact tagcataatc gttaattgct
    19261 ttattcaagg ctttaaatga tgttacttta gcaccaaata tctttataac ttgaattcct
    19321 cggatatatt ctaccgtttc agagcttaac acatctaacg attcttgata tttttgaata
    19381 aaatttgtat tctctgtcat tttctttaac aagaatacac caattactaa catggcgatt
    19441 agaaccaatc caattttaaa attaatgaaa aagcctaagg caactgataa aacaggtgtt
    19501 actatggctt gagcactatc tggaatcaag tgagcaattg ccatatgtgt tttagccgcg
    19561 ttgtcatcaa ttgtctttcg aatatatccc gaagaattta aatcaaaaaa acgaaaactt
    19621 gcttctgtta aaccgctaat tccctttttt ctcaaattag tctctaagcg aaacccaagg
    19681 atatgagaaa ataagccaga aaaaatataa aataaagctc ctaaagttaa ccaagcaaca
    19741 gtttgaaccg cataactctt agctaaatat tcatctccta caataattag agacttaaga
    19801 aatttgtaaa tactgtaata tccatagact gttaatacga cagaaaaatc agaaaataaa
    19861 gtggctaacc atccgtagta tttcatttta gggacataac taaataattt tttgtatact
    19921 ttcatttttt cctcccccgc attcaatttc ttctcttatt cgtttacaac tgttaatgct
    19981 ttccgtaata gcgtaaatta gagatgtaca aacagataga aggtaaacta cgttctattt
    20041 tttgtatttt tttaagactt ttcttccaat caatacacca atcatagata aacttgctac
    20101 aactaacact gaaatgattc cccatatacc taccgcatag tggatcattg catccattgt
    20161 tgcagcagat tgtcctttat ctatccaatc ttgacgaaaa cgatctgtaa agaaccatat
    20221 aggaatccac tgtccggcag cactgcctaa ttgcattaga gcccaagacg caacttgagg
    20281 aattgctcga tcatatccaa atacagatag aataatatca gctaagatcg ccatactaat
    20341 cgaactgata aaccaaggta agtacgcccc gcccattaac gtaaaaaata acaataaaac
    20401 aattgtgtaa atagtaaaaa ttccttttct agggtagtta tagctaatat aaacaaatat
    20461 gattccagat aataatccaa aaatccctgg ggatatgctg tgaccaaacg ccccaccaat
    20521 actactaacc attattgaaa aaaagtaaat tactagggaa ataactgtag ctaaaccaat
    20581 aaaaatataa tcttttgttt tcatatatat tctcctcaat tctatttcgt tatgtcatta
    20641 aaaatctgtt ctatcaaagt tgaatcttct actctaagtt ttatatcttt ttttattcca
    20701 ccatttttta aataaataat tctattgcat gttttataaa gaaattccgg atcatgagtg
    20761 gctataacta ctgcaccctt ttcttttaag tctttaataa ggtcagcaat cctttccata
    20821 ttaatataat ccaacccact tgtaggttca tcaaatagaa ataaattagt ttttgacaat
    20881 gaagctatag aaaccaataa tctttgtttt tctccaccgg ataaatcaaa cggtaattga
    20941 tctttcattt tataaagttc catttttttt aaaatttttt cttgctgatc tttactaact
    21001 atttcattcc ccagggctaa ctcgctcctc actgattctg tgaaaaattg gtaatccatt
    21061 tcttgcatta ctaaaaacgg cgatgacaaa ttttttttat tttcgattat ctttcctttg
    21121 gtagggcgaa taatcttcat gagtattctt agtaaggttg ttttccccac accgtttttc
    21181 cctaccaaac caataacatc tccaactttg acatcaaaat ttatgtcttt tagaatattt
    21241 tcataagtaa tttcttcaac ttttaataca tctgcactta ccttttcgat atagggaact
    21301 tcaatcgaac tattaaaaat gtcaaatttc cttaatgcgt tattgttttc agtttttaac
    21361 aactgaatag ttgtagtttt tacagttcta tttttaacaa atagaacttg atcaattaat
    21421 tctttcaaat agtaaaaacg atgttcagct ataacaatag taaatccttt attttttaaa
    21481 tcacaaagta agtcagcaag tttcttagtc gctttgaagt ccaaatttga agacggttca
    21541 tccaatataa ttaatttaga gtttagcgat aaactacatc caatagaaat tttctgccgt
    21601 tcaccacttg atagcgaaaa aatgttttta tctaatatat ttgaaagatc taataattca
    21661 gctaattcat tgattctttt atccatatgc tcttttgtaa atccaaagtt ttccatcgaa
    21721 aatactaact cactcgttgt atttgttgta aagaattgtc ctctaggatc ttgacttacg
    21781 tagccaatat tttttgatat actttcttgt gttaaggatt gtagcgagtt attttcaaat
    21841 aaaatttccc caaccaattt tccgtcataa agtcttggaa taagtccatt cattaacttt
    21901 aatagtgtgg atttcccact cccagaagaa ccagtaatca atgtaagact accttttttt
    21961 attgaaaaat taaggtcaac aagcgcttgt tccttaacat ccttatatga aaaagaaaca
    22021 ttgttaaatt caaacaattc tttcacctca aatcaaaata cttaagaaaa aaatagtaac
    22081 ggaaaacagg atgatatagt ctaataagct catgtttgtt ttatagtaag aacttctttt
    22141 cacaggagat tctatcccct ttgttattgc attagcggtc atttcttcag caatcatagt
    22201 tgcacgtata agaacgggaa ctaacagaaa ttccaaatat tgcagaggct gaaaaaaaga
    22261 caagcgaatg tttctcattt ttaaagattc tttaatcatt cttatttcag aacgataagt
    22321 cggaaagaat ctgatcacta ctgtaatact taacattatt tttttcggta aatgtatttt
    22381 ttctaaagag gataataatt cattgctagt atagacacta accaacaacc atgagatcat
    22441 tacgaccggc aacattcgaa atacaatata taaggatgtc ccaaaaaata tagtaaaaaa
    22501 ctctatcttg atagcatcaa taattttcat tactaaaaac agaactgaat aaatcaagat
    22561 gaaataaata catgtcttta ttttacgaaa catcaatact aaaactgtag caataatgaa
    22621 acaccccact tgaaatatat ttccctttcc taaaaaaata atgaccggaa aaaaaatatt
    22681 taaagtaatc aaggttaacg gattgatttt tgacactctt tcacctccaa aaaataagat
    22741 cgcactgtta tcttaagctg ataaaaatgc accgttattc agataacagt gcgatcttat
    22801 caaaaagcat aactgagaac aattctcaat gcaagctttt ttttaattaa ctcagtaatt
    22861 caatccaccc aggaacagaa aattgataca atcttctggt taatagcata gtcttttctt
    22921 ttgaatagct atgcttcaat atatcataga atgtagcgta gaatgagtaa atgtagaagt
    22981 ggatttcttc ttcattaaag actaaatttt gattgatcat tccgatagtc tttaacttat
    23041 ctagacaaca gactgtcttt tttgtcacaa atgatgtaat tttttcaaca atatcttgat
    23101 atttggttcc agctgattgg aataaaacca aatcgaatat acgtttattc tcaaaaatat
    23161 aattaataaa tggatctaat tcattgaagt tctctctcca acttttctct atatctatat
    23221 tttctaagtt taagaggtat ttggtaaact cttcattata catattaata agcgcattaa
    23281 tatgcggctg aataatttct tcaaataacg cttccttaga agtaaaatgt ttataaaaag
    23341 cacccgtagt tacgcctgcg gtcaagcaca gttgccttat cttagtttgc tgaaatccta
    23401 ctttttcaaa atggcttagt ccactttcta ttaatttttg gtgagttgta atataatctc
    23461 tggtttctat gggtacttcc tcctaataag atgaattaac tatattatct tacacaggac
    23521 ttgaagtttc aatcgttaac gtctattact gaactcattc cttagagcta aactaatgag
    23581 aaagagcaaa ataactgata caaaaagcaa tcctacaaga attaatagac tcatctaaat
    23641 cattcacctt ttctaaaata atccgagaaa gatttaaaaa aattatatcc agctattagg
    23701 ataagtccta tcataatcac tccaatagcc attttcttat cctccctaaa aataaagcct
    23761 tttacttaaa accttttttt gtaatcgtca ataaattttt tccctttatc agttaattga
    23821 aatcctatat ctaaatagtc ctcatatcta agtttagtca gcatctcact tacagatgct
    23881 ggactaacac ttagaacttt tgctaaatca ttatttttta atttcttttt tctttttgat
    23941 aattcctgaa ttgctagtaa ataaattagt atagtagttg ttttaatttg taccatacct
    24001 accctccaaa ttatttcgaa aggccttcag caattttatc caggttccat ttcatcatcg
    24061 catagtaact atcaccatct tgtccttttt ctgcaattga atcagtaaaa atcgttgaat
    24121 agataggaat attggtatct tttgatactg ttttcattgg tctatcgtcc acactgcttt
    24181 ctacgaataa ggagggaact tttgttgtgc gtaatttttc aactaagtgt tttatttgat
    24241 ctggtgttcc ttcttcttca gtgttgattt cccaaatgta agcagaaggc acattatacg
    24301 ctttcgagaa atatttaaag catccttcac ttgtaacaat cattttttta tcattcggaa
    24361 ttgaagcaaa tttagattta gcttctttgt ctagagaatc caatttttca atatacttat
    24421 ctagattttc tttatagaat tttttattat caggatcttt ttccgctaac tgtttttcaa
    24481 tatttttagc gtaaataata ccgttttcta aatttaacca agcatgggga tcttccttcc
    24541 ctttctcact ctgaccctct aagtaaataa catctatgcc atcacttgct gcaaaatagt
    24601 ctttgttttc ctctttgttc gcatttttta ctaattttgt aaaccaagca tttcctccag
    24661 tttccaagtt aacaccgtta taaaaaatca aatctgcttt tgaagttttt tgaacatctt
    24721 caggcaaagg ttcatattcg tggggatctt tcccaatagg tacgatactg tgtaaatcaa
    24781 ttttatcttt tgctatattt tcagtaatat ctgctaaaat cgaattagta actactacct
    24841 ttaatttttc gttcgaagcc actgtatctt tgtctttact atttgttgaa catgccccga
    24901 atataaaaag agcaatcaaa atccccagac ttcccagtac tgctttccat tttctcatca
    24961 taactttctc tccttctttc ttaaaaattt ttgttttggt gagattagaa aactaattac
    25021 aaataagaat gccgctgtta aaacaatact tgatcctgct gctatgttaa aactataacc
    25081 aatgaacaaa cctagcaatg atgagcacgc tccgactgtc gccgaaataa atatcatagt
    25141 ttttaaactg tttgcatata aatatgctgt agcagctggt gtaattaaca ttgcaacaat
    25201 taatatagtt cccacacttt gcatagctgt tactgctact aaagttaata gaatcattaa
    25261 tagataatga taaaaactga cattcatccc cattgctttt gccattaatg gatcaaaaga
    25321 agtgattaat aattctttaa aaaatagaac aactgtaacc aacactaaaa cagaaacgcc
    25381 aattgtaatc cacttatcaa tatcttgtac agctaaaata tttccaaata agatatgaaa
    25441 taaatccgtt gagctatttg caactcctat aaggataact cctaatgcta aaaaagaact
    25501 gaaagtaata ccaattgctg tatctccttt tattacacta ttgcttttta taaaagtaat
    25561 aatgatagaa gctaatagac caaatacaat cgcaccaata aaaaaattaa tacctaaaat
    25621 ataagaaatt gctactcctg gcaaaacagc atgagaaata gcatcaccca taagagacat
    25681 tcctcttaaa ataataaaac aacctactgt tccagaaaca atccctataa ctacagatgt
    25741 aattagagca ttctgtaaaa agtgaaagtc atacagacca ttaataaaat tttgaagcat
    25801 attattcccc ttgtatatta gagttagggt tttaaccttc cggttttgat tggataaccc
    25861 tatgaaccat cgttatttta atttggtatt aactcatttc ttttgagata atatatttat
    25921 tggattgaga ggctaagccg ttcccccctc tccaataaat atagtatctc cataggcttt
    25981 ttttaaattc tcttcattaa atacagattc tacacttccg tgagcaatta gatttcgatt
    26041 caaaagaata atattatcaa aatacttctt taccttgctt aaatcatgat gcacaattag
    26101 cactgttttt ccctgatgtt tcaattcttt taacgtatcc ataattattc gttcactaac
    26161 taagtctatc cctacaaatg gttcatctaa aaatatgaaa tccgcatttt gagcaagaca
    26221 tcttgctaaa agtacacgtt gaaattgtcc tccagataat tctcctattt gatgattaga
    26281 atattttccc atatcgacct tttccaaagc ctttgaaact ctttgccatt ctgcattttt
    26341 aattctttga aaaactttca ttccggcata tgttcccata gatacacatt cttttacttt
    26401 tattggaaaa gtaaaatcaa tatcagcttt ttgctctaca tatgcaatct tcaccagttt
    26461 tttattgata tcttcattat taatggagac ctctccctga tgagggataa tatttaacat
    26521 tgctttaagc aatgtagatt ttccagcacc atttggacca ataatacctg ttaaagcacc
    26581 ttcttgtatt tttaaagaaa tctcgttcaa tgctaaaaaa tcgttataac aaacattaag
    26641 ctttttcact tctaacataa ctttctcctt ctaaatgata atgattatca cgatcatatg
    26701 gtatacaaaa attatatttt agtcaaccct aaattttata atttagattt ttttctgttg
    26761 ttgaagatta ggatgtcaaa attatttgaa actactcgta tagtaaatag taagtaattt
    26821 tcaaaacacg aagaaaaaca aaaagaaaaa aggaaacgcc gaagcatttc ctttcagtga
    26881 tttaatgaga acaacacgat ttgacttaga gtctcaaaaa gtcgaatagg tacactcatt
    26941 taagtgtctc cattcgactt tttggggatg agctggctat tgaggtccgc ttaccctatt
    27001 gaataaatac aagattgggt atttctaata agtccgccct tcatattggg gtgatcgggg
    27061 cgaacatgcc atcttttcat ataccacctc ctcgacactc aataatcaaa gattctcgtt
    27121 aatcttcttc gatgcttgca atgatgtttt caatattcat ataacgaaaa tcttcttgtt
    27181 tgatataaac gatctgagcg gtacattttt cctttttgat gatttctttt actttttcct
    27241 cagaacgtgc gacctgcggc gttaaaagta aaacgtcata gtctttataa ttcagttttt
    27301 cttcaacgtt tcggatcgtt gcataatcta tctcatacga tagatttttg gctctgatcg
    27361 tttcaagcat ttttgatacg agcagcgacg cactgattcc ggtctcgcaa ataatcaata
    27421 gatccttatg cataataccc tcctgttttt agcctgcaaa gccaattggt gaaaatgcca
    27481 cataagttaa aataacaatg actaccaatg ctatagcagt caccttggtg tatttccaag
    27541 gctcgatatc gacctttgta tcgaatgagt tcaacacaaa ttctccatca ggtttcaatt
    27601 tggaaaccac catcaaaatg ataatgtcca gaacgaataa tgccgtcaaa acataaagga
    27661 aatggatatt ttggaaaagc atttttgata gtgcatacaa gacgatatgc acggcaatcg
    27721 tcgtttttgc cccaaaagca gttgcttttt ttgaataaaa ggcaaagaga atgatcacga
    27781 gcagcggcat gttgtatagt ccattgaatt cttgaacgaa ctgatacaat ccagccggtg
    27841 caaaagaaat gaatggcgct acgataatgg agataatccc cacaacgacc gttactgttt
    27901 taccagcacg agcgatttgc ttatcatttg ctttcttatt gataagcggt ttataaaaat
    27961 ccagtgaaaa caaggtcgat gtcgcgttca aagctcccgc aaatgatgat aagatcgcgc
    28021 caaagataac agcggcgaaa ataccaaaga tcattttagg caatacttca ctgactaaaa
    28081 aaggatacgc gttatctgga tttgacatta aactatcgcc aaaaatattg cgagcgacga
    28141 tccctggaaa gacaaggaat aacgcaccta agattttgaa gacgccgact aggaaagcgc
    28201 ccttttgtgc ctcagctaaa ttcttgccgg acaatgcttt ttggacgatc atttgattgg
    28261 tacaccagaa atacagattg ttaaacagca tccctgtaaa tagtgtcggc catggaacaa
    28321 cagccgagtc gatcgatccc acagagttaa gcagccatgg cgtgtttacc acaacgtgtt
    28381 cgatcccgcc aacaaagctg ccgtcaccaa gcttcattaa gcctaaaatt gggaccagca
    28441 gaccacaagc cagcagaccg actccataaa tggagtcact attggcactt aacgacaagc
    28501 cgccgatcag cagatagagg atgccgacaa taccaattgc catcgctaca attatgatcg
    28561 cgacgatcgg ctggacgccc agcagctcat caatatggaa gatcttattg aacaccagcg
    28621 atccagaata aagaaccacg ggtaagaaag aagtcatata ggtcacaata aataagatcg
    28681 aaataattcg tttggtaacc gtatcataac gaatctcgat gaaatctgag attgtattga
    28741 tgccgtattt aaaatatttt ggcaagaata tcacagccaa agctacgatc gcaatcgtag
    28801 cagttacttc ccaggccatt acttccatcc ctgcatgata actttgacca ttttgtccga
    28861 ctatttgttc ggtggacagg ttcgtcatga tgatcgtgcc ggcgattggc aaagcagtta
    28921 agctccgccc tcccatgaag aacccttctg atccagaagt atcgacactt ctggatctag
    28981 aataggcaaa taaccataca cagatgacaa tcactaggaa actgattata gaaaaaagat
    29041 tcatcgtcta gctccttttc aatagattaa agaccggtga cctctcgaat gtagcttctg
    29101 gctttgactg catattcaaa tggattggct ttagccgggt cctgttctgc ttcaactacg
    29161 atccagcctt catagtcgct ggcatggatt gctgtccaga ttggagtgaa atcaatcatc
    29221 ccatcaccag gaaccgtgaa gacgcctttc ttcacgccgt ttaagaagct gtctttttcc
    29281 ttttctactt cttcagccgt ttcttgacga atatctttga aatggatgtg tttgatacga
    29341 tcttgatgac ggttgtaaac cgcgattgga ttttcaccag aaaagaccaa atgtcccgta
    29401 tcgaacaata atttaacttt gtctggatca gtcatttcca ttaaacgatc gatttcttcc
    29461 gtcgtttgaa cgccggtacc catgtgatga tggtaaacga tctccatatc cttttcgtgg
    29521 gccaaatccc ctaatttttc taatccttcc gccagttttt tccactcttc atcagtgaaa
    29581 actggtttat catcaaagac tggcgctgtc ataatccctt ggatactatg accctgctca
    29641 gctactacga tgactttagc gcccatcgca tgtaagaaat cccgatgtgc tttgaaggct
    29701 tcggcagttt cttcaaaagg tttagttgtc agaaacgcac tgaaccatgc actggcaacc
    29761 tttaagccgc gaatattcaa atattgttcc aacacctctg gatcttttgg atatttgttg
    29821 ccaatctctg ttccggtgaa cccagcaagg gccatttcac tgatacattg ttcaaaggta
    29881 ttttcactac caagctcggg catatcatca ttggtccacg cgattggtgc gatggctaat
    29941 tgaatttgtt tggtcatatt ctcacactcc tgcttatttt tttagttgta ctaaactctt
    30001 cgtatcgaat gattcttgac aagccaacgc gatcttagtt gattgcaatc catcttctgc
    30061 attaaccgct ggttgacgtt tttcttgaat acatgagaca aattcttggg cttcacgaat
    30121 gaaggcttct ctgaatcgtt ctgggaagtt ttgtgaacat ggacggatga tcccttgatc
    30181 gttcatgatc gtcacaagat ttttctcagg cgcttgcgct acccgcagca ttcctttggt
    30241 tcccatgatc tctgtttcga catgatagcc atgggctgcg tttctgccgg caactagtaa
    30301 agctattgtt ttatcgctca ggctcatcat tgcggctcca gtttcaagct caccagcctg
    30361 atccaattct ggatacgccg catttttccc aatcgcccac acttgatcga cttcttggcc
    30421 ggtaaaccag cgaaccaaat caatatcatg gatcgccata tctaagaaca agccgccgct
    30481 gtcgttattc atggcaaatt tgacaaagct ttccaagcct tcgctcggat cgatcccata
    30541 acaacgaatc agtgtgattt cgccgatttc gccatcttct accattttct tcgcatactg
    30601 atacgactca tcatagcggc gcatgaagcc taacatgaag acctgttcag gatgctcttc
    30661 gatgactttt tgggtctttt taatatcttc aacttcaagg cctaatggtt tttcagtaaa
    30721 gacatgcttg ccattttcca tcgccaagcg gacttggtca cagtgaaagc ctgatggtga
    30781 aacaataaag actgcatcga tcacggaact tttgaccatt tcttcatagc tggaaaaagt
    30841 atgcttgacg cctaatttct tctgtgcgaa tgctaattct gtttcaacta aactgcacgc
    30901 agccgtaagc tcacaacaac tgacacctgt tgctaaattt tgtgcatgta cttttcctaa
    30961 tcttcctaaa ccgacgatgc ctactctaat gttgttcatg aaatacctcc gttttctgag
    31021 aattactcat tgtatagtgc tggtcgttca tccatttgaa tcattacttt tgtttttgtt
    31081 tcacgagact catgacaagc catcatggtg atcgctgcta catacccatc ccaagcggta
    31141 ggaccgacaa ccgcatcatt tttgatcgaa tcgatccaca gcttgaattc ataatcatag
    31201 gcatccaaaa agcgggtctg ccaatctggt gaaacaggtg tgtaattttt ttcttccgat
    31261 ttaattcgtg tataggctgg gtccgtcatt cctacttctg ccgtttcgaa aaccacatca
    31321 catttaatat cgtagccaaa gcggcaattc acaaagattt ccaaatcaat cgttacaccg
    31381 gattttgttt gaaagatcag cagctgcgga tcatgcaaat cggcatggga gttgctggtt
    31441 tttttcggca agatcatttg aacagattca taatcttcat ttagcaacca gcgaagcaca
    31501 tcaatctcat gaatcgcggt gttgctgatc gccatcggtg ttgtgtagtt ttcatctgcg
    31561 ctaggatttc tatgggcaca atgcatcatt aatgcttctc cgtattgctt cgattcgatt
    31621 gcttctttca gttcaatgta gccgcggtca tagcggcgca tgaagccaac ctgaaccaat
    31681 ttcttcccat aagcaacttc cgcatcaacg atccggcggc agcctgctgc atccatcgct
    31741 aatggctttt cgcagaaaac atatttccca tgcttgattg cttctaacac atactgctca
    31801 tgggtcgggt cccaagaagt cacaacaacg acatccacat cttcagaagc gatcaatgct
    31861 tctccggttt caaagaattt agcatcgaca cgtttggcaa cctctttagc agcttttaca
    31921 ttgatatctg agactgctgt cacataagcc ccttgtgttt tctgattgat cctgtcgata
    31981 tgctcgatgc cgattgcacc tgttccgata acgcctactt ttactctcaa ttacttatcc
    32041 ccctgttctg ttgtttaagc acacatagta tgcgcttaca aaattattcc tgtgtagctt
    32101 ttattcttaa aaggtagagc cctctctttg ctccgccttt tactacccat aagcttgtac
    32161 gtataattcc ttaatttgac tatgactagg caccttttta ttattttgcg gacttccgct
    32221 ggtcaacgca tccgcggcca ttttgtctaa ggctgccata aacgcttgct gatcaatacc
    32281 ataatctcga atcgttggga tcgacagctg ctcacagagc tcttggattt ttttaatcag
    32341 ataatccgca gcctcttcca gcgataaatc ttcggctgcc ggataaataa atctggcgat
    32401 cgtcgctaac tcagtctgaa tagcatcctt tgagaattca aaaaagaccg gcaataacat
    32461 cgcatttgat atcccatgag gaatgtgaaa aagtgccccc accggtcgac tcattccatg
    32521 aatcaatgtg actgacgcat tcgaaaaggc aatccccgcc tccgttgaag ctaagctcat
    32581 ttgttctctg gcttcagtgt cgtcgctatt ttcatatgcc tgagaaagcg tgttcaaaat
    32641 tttcttcatc gcttccagtg aaaatagttg cgttacttca ttggctttga ctgaaacata
    32701 agattccaaa gcgtgacata gcgcatcgac tcccgttgcc gcggttactt ttggtggtac
    32761 agttttcgta aaatcagagt caacgattga gatctgtggc atgaaaacga gatccttcat
    32821 catcattttg actgctgttt ttgtattggt aataactgcc acatcggtta cttccgaacc
    32881 agttccagca gttgttgaca ctgcaatcag cggaatgccc gcttgcagct gatcaaaatt
    32941 tcttgcatga atcgcttcga gacttaattg attagcagcc aaaacggcta ccaccttggc
    33001 tgtatccaga cagctgccgc caccaaaagc aatgatatga tcacattgat gcttctgaaa
    33061 aagcttcagc gcatcataaa cattttcttg cgtcggttcg gcttgaatgt ctgtatactc
    33121 cgctaattga tcatctgttt ttcccaacag ctccttgatc ttttgaagat gcccggtctg
    33181 ttccataacc gtatcactaa tgattaacgg cttgttgcct agttgttctg attcttccat
    33241 aagaaattgg attgttccgc cgccaattct taaattggca ggcattttca gttgaatatt
    33301 cacagaaaaa acctctctct ggcttatagc ctataacaga atcctcgaag ctctttaaca
    33361 gagcttcgaa gcaaatcttt aaatctcact ttgcgcataa cgtgctgtaa caactttccg
    33421 atgggtataa aactcaacac tgtctttgcc attggcatgc aaatcaccaa agaaagagtg
    33481 cttccagcct gaaaaggcaa accaagccat cggtgcaggc accccaagat tgacccccag
    33541 catcccagca tcaacatttt ctctgaagta gcgaatcgct gatgcgttgt tggtatacag
    33601 acacgaacca ttcgcaaatt cagattcatt cgtcagctca acggctgcca tcaaatcttt
    33661 tacccgcacg attgatgcga ccggggcaaa aatctcatcc tgccagatct tcatatccat
    33721 cgtgacatta tcaaaaatcg ttggtccaac aaaatagcct ttttctggaa tgttttcgcg
    33781 accatctagt accagtttcg ctccttcatc gacccctttt tggatatagt caaaggtccg
    33841 ctgctgtgca tcttttcgaa tcactggtcc taaaaagacc ccttcgtcca agccattgcc
    33901 gatcttgatc gcttttgccg cagccttaaa tttttcaaca aactgatccg cgatttcctc
    33961 ttccaaaaca atgacggagg ctgccatgca gcgttcacca gcagaaccaa aagctccgcc
    34021 aataaggtcc ttgactgccc gatcaatatt ggcatctttc agcacaacaa catgattttt
    34081 cgctccagtc aacgcttgta cccgttttag attttttgtt ccttcacggt aaacgtattc
    34141 accgacattt tttgatccta caaagctgat gccttttacc agtggatctt gcagcaatgt
    34201 gttgacaaca tcgtgggcac catagacaac attaaaaaca ccgctaggaa agcctgcttt
    34261 ttcaaccagc tcaacaattt tctccatcaa caatggtgtt ttttctgaag gcttcagcac
    34321 caccgtattt cctgccgcca gagccatcgg gaagatccag aagggcacca tcattggaaa
    34381 attaaacggt gtgatccctc cgattactcc gattgggtaa cgataattcg tgatctcaat
    34441 atcagtcgcc gctgttgata aagaatctcc catcattaaa ttggtgattc ccgctgcgtg
    34501 ctccacattt tcgattcctc gttgaacttc tcccagtgac tcggacaatg atttcccatt
    34561 ttccagcgtg atcaaacgcg ccaattcact tttatgatct gttaaaagct gatgcagctt
    34621 gaacagataa cgtccgcgaa caggaacagg aacttttttc caagtttgaa acgcagcatc
    34681 ggcagcttta actgcttcgg ctgtctctgc tttgctagac aacggtacat tcgccagcgc
    34741 ttcttctgta gccggattca ttacttcttc aaactctgtt gagcgactag cgacccaacg
    34801 accatcaata taatttctta aaaatcttgt cattta
//
LOCUS       DAYYEF010000026        34695 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000026 DAYYEF010000000
VERSION     DAYYEF010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.026"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..185
                     /locus_tag="ACHA1B_001447"
     CDS             <1..185
                     /locus_tag="ACHA1B_001447"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702216.1"
                     /translation="IPRNWLLNTVYQEVVSLPFNSESQGAISKNSFSGLLTIVTCDRG
                     VGRRTPFKEEVVKSAV"
     gene            complement(348..2240)
                     /locus_tag="ACHA1B_001448"
     CDS             complement(348..2240)
                     /locus_tag="ACHA1B_001448"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702217.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2237..3964)
                     /locus_tag="ACHA1B_001449"
     CDS             complement(2237..3964)
                     /locus_tag="ACHA1B_001449"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702218.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3980..4630)
                     /locus_tag="ACHA1B_001450"
     CDS             complement(3980..4630)
                     /locus_tag="ACHA1B_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HFM8702219.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4834..5130
                     /locus_tag="ACHA1B_001451"
     CDS             4834..5130
                     /locus_tag="ACHA1B_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HFM8702220.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5322..5942
                     /locus_tag="ACHA1B_001452"
     CDS             5322..5942
                     /locus_tag="ACHA1B_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HFM8702221.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(6034..7200)
                     /locus_tag="ACHA1B_001453"
     CDS             complement(6034..7200)
                     /locus_tag="ACHA1B_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFM8702222.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7212..7565)
                     /locus_tag="ACHA1B_001454"
     CDS             complement(7212..7565)
                     /locus_tag="ACHA1B_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFM8702223.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7693..8715
                     /locus_tag="ACHA1B_001455"
     CDS             7693..8715
                     /locus_tag="ACHA1B_001455"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HFM8702224.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8734..8895
                     /locus_tag="ACHA1B_001456"
     CDS             8734..8895
                     /locus_tag="ACHA1B_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702225.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(9154..9588)
                     /locus_tag="ACHA1B_001457"
     CDS             complement(9154..9588)
                     /locus_tag="ACHA1B_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702226.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9698..11557)
                     /locus_tag="ACHA1B_001458"
     CDS             complement(9698..11557)
                     /locus_tag="ACHA1B_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFM8702227.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            11558..11698
                     /locus_tag="ACHA1B_001459"
     CDS             11558..11698
                     /locus_tag="ACHA1B_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoglycerate dehydrogenase"
                     /protein_id="HFM8702228.1"
                     /translation="MLAPSFLSIKECCFSYFSCTKFESKERKEELMKSKYSLSLWPFW
                     FL"
     gene            complement(11675..12834)
                     /locus_tag="ACHA1B_001460"
                     /pseudo
     CDS             complement(11675..12834)
                     /locus_tag="ACHA1B_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0051287 - NAD binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            complement(13141..14565)
                     /gene="araA"
                     /locus_tag="ACHA1B_001461"
     CDS             complement(13141..14565)
                     /gene="araA"
                     /locus_tag="ACHA1B_001461"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008733 - L-arabinose isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0005996 - monosaccharide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HFM8702229.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14581..15279)
                     /locus_tag="ACHA1B_001462"
     CDS             complement(14581..15279)
                     /locus_tag="ACHA1B_001462"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFM8702230.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15236..16897)
                     /locus_tag="ACHA1B_001463"
     CDS             complement(15236..16897)
                     /locus_tag="ACHA1B_001463"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004856 - D-xylulokinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0005998 - xylulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HFM8702231.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17115..18515
                     /locus_tag="ACHA1B_001464"
     CDS             17115..18515
                     /locus_tag="ACHA1B_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0051119 - sugar transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HFM8702232.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18767..19846)
                     /locus_tag="ACHA1B_001465"
     CDS             complement(18767..19846)
                     /locus_tag="ACHA1B_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM8702233.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19932..20891)
                     /locus_tag="ACHA1B_001466"
     CDS             complement(19932..20891)
                     /locus_tag="ACHA1B_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HFM8702234.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDTLIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20903..22414)
                     /locus_tag="ACHA1B_001467"
     CDS             complement(20903..22414)
                     /locus_tag="ACHA1B_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA];
                     GO_process: GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-arabinofuranosidase C-terminal
                     domain-containing protein"
                     /protein_id="HFM8702235.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22436..22999)
                     /locus_tag="ACHA1B_001468"
     CDS             complement(22436..22999)
                     /locus_tag="ACHA1B_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HFM8702236.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(23005..23868)
                     /locus_tag="ACHA1B_001469"
     CDS             complement(23005..23868)
                     /locus_tag="ACHA1B_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702237.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23882..24778)
                     /locus_tag="ACHA1B_001470"
     CDS             complement(23882..24778)
                     /locus_tag="ACHA1B_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702238.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24953..26242)
                     /locus_tag="ACHA1B_001471"
     CDS             complement(24953..26242)
                     /locus_tag="ACHA1B_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8702239.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26214..27731)
                     /locus_tag="ACHA1B_001472"
     CDS             complement(26214..27731)
                     /locus_tag="ACHA1B_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HFM8702240.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27929..28819
                     /locus_tag="ACHA1B_001473"
     CDS             27929..28819
                     /locus_tag="ACHA1B_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HFM8702241.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28892..29716)
                     /gene="nadE"
                     /locus_tag="ACHA1B_001474"
     CDS             complement(28892..29716)
                     /gene="nadE"
                     /locus_tag="ACHA1B_001474"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_function: GO:0008795 - NAD+ synthase activity [Evidence
                     IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HFM8702242.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29728..31200)
                     /locus_tag="ACHA1B_001475"
     CDS             complement(29728..31200)
                     /locus_tag="ACHA1B_001475"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HFM8702243.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31837..32199)
                     /locus_tag="ACHA1B_001476"
     CDS             complement(31837..32199)
                     /locus_tag="ACHA1B_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HFM8702244.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32422..33174
                     /locus_tag="ACHA1B_001477"
     CDS             32422..33174
                     /locus_tag="ACHA1B_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFM8702245.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33314..34237)
                     /locus_tag="ACHA1B_001478"
     CDS             complement(33314..34237)
                     /locus_tag="ACHA1B_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8702246.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34252..34524)
                     /locus_tag="ACHA1B_001479"
     CDS             complement(34252..34524)
                     /locus_tag="ACHA1B_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702247.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10240 a         7220 c         5986 g        11249 t
ORIGIN      
        1 taataccgag aaactggctt ttgaacaccg tttaccaaga ggttgtgagc ctgccgttta
       61 actccgagtc acaaggagca atttcaaaaa acagcttctc aggtttgttg actattgtga
      121 cttgtgaccg aggagttggc aggagaacac cgtttaagga agaggttgta aaatcagcgg
      181 tttgacctga gtattagaga tacaaaacgg aaaaatagct tctcatattt tgccgttttt
      241 tgagctaata ccgaaggaca gctgattgaa caccgtttat tcggaaaaag ggactgtgac
      301 acgacttttg tcacagcccc taaaaaaaat aataaatttg tactattcta tgaagcttct
      361 tcttcagaaa actgactgtt ataaagatct gcatagaatc cgtctttttc catcaatgta
      421 tcgtggtttc ctgtttctac gatcgaacca tgattcatca caataatgtt gtctgcatcg
      481 cgtattgtag acaagcggtg agcaacaacg aaacttgtcc ggttttccaa taggcggttc
      541 atcgcttttt gaatcagtat ttctgttcgt gtatctacac tagatgttgc ttcatcaagg
      601 atcaggacat ctggatttgc taagaatgcc cgcgcaattg tgattagctg acgctgccct
      661 tgcgaaatat tgcttgcatc ctcgtttaat acagtgttat atccttctgg caatttacga
      721 acaaaatcgt ctacgtgagc agctttagca gcctcaatga tttgttcgtc tgttgcatcg
      781 tcgttcccat atttgatatt gtcatagata cttcctgtaa acagccaagt atcttgcagt
      841 accattgaaa actgtgcgcg caattcatca cgtgaaagat cacgggtatc tacaccatcg
      901 taacgaatac tacctccaga aacatcgtag aaccgttcaa gaaggttgat cagtgtcgtc
      961 ttccctgcac cagtcggacc tacaatagcg accatctcac caggtttgac atccaagtta
     1021 aaatcagtca ttagcaagtt atctggtgtg tagccgaatt gaacattttc aaaacgaact
     1081 ttgtatggtg tatctttttc ttctggaagg ccagattttt cattggacat ctcttcttca
     1141 tccaacactt caaatacccg ttcggctgaa gcaactgttg attggatagt gttcatcaaa
     1201 cttgcaagtt gagtgattgg ttgagagaac tgtgttgtat attgcaagaa cgcttgaaca
     1261 tcccctaatg tcatgttccc atttgcaact tttactccgc ctagtacagc gacgaacaca
     1321 tagcctagat ttttaacgaa attcatcaac ggcatgatga ttgccgaaat aaattgagct
     1381 ttccaaccag cggcatacag attctgattt tctttttcaa atacttcctg gtctttttca
     1441 gtatgattga atgttttaac aatggtatga ccaccatatg tttcttctac ttggttattc
     1501 aataaaccta aacttttttg ctgatctgcg aaaaacactt gtgatttcgg cgctacgatc
     1561 atcacgatga tcaagcttaa agggatcatc aataacgcga ctaacgtcaa ttgccagctg
     1621 attgaaagca tcatcacgat gaccccaatc aatgtgactg cactagttac aaattgagtc
     1681 aaattttgct gcagcgtgct tgcgatgtta tccatatcat tgattgctcg agacatgata
     1741 tccccatttg tatgtgtatc ataataggaa atcggtacac gattcatttt ggcttccaaa
     1801 tcatgacgta attcataaac tgttcgttgg gaaacacgtg tcataataaa ttgctgtaaa
     1861 aagttgaata cagcagaaat caaatacatc acgattactg tcgcaatgat ctgcgcgatt
     1921 ttatcaaagt ctatcggaaa ttttgttact tgttggcctt gttgcatctg ttgagcgcca
     1981 gccattacac ctttgaatat ttctgtggtt gctttcccca agacctttgg tgtttggatt
     2041 tggaagatca cggctgctat tgctagtaca aatacagcga tgatcgcaac catacgttta
     2101 gacatatagc caaacaatcg gcgtaccgtt ccccagaaat ttttaggctt ttcacctttt
     2161 acaccgagat ttctgccagg tccaccatgt cctggaccgc ctgctggtcc atgagaggga
     2221 cgtgtgtttg ttttactcat gctaagtcct cctctcttag ttgtgaatga acgatttctt
     2281 gataagtttc gtttgttgct aatagttctt catgtgttcc tttgccaacc agttttcctt
     2341 catctagcac aaggatcata tctgcatcca ttactgtact tactcgttga gcaactaaaa
     2401 cggtgatact ttctttcata ttcgttttca atgcttggcg aagattggca tccgttttga
     2461 aatccaacgc tgagaaggaa tcatcaaaca catagatatc tgctgttttg actaatgccc
     2521 gtgcaattgc cagacgctgt ctttgtccac cagagaagtt tcctcctcct tgttccacat
     2581 ggctatctaa gccatcttcc atctctgaaa caaaatcttt agcttgtgcg atttctaatg
     2641 ctttccaaat catttcatct gttgcatccg gcttaccata ctgcatattg tctcggatcg
     2701 ttccagagaa cagaactgct ttttgaggaa caaagcccat taattctcgc aaattatatt
     2761 gagtcatgtc actaatgtcc gttccattta tttggatcga accagattcg atgtcatata
     2821 atcgagggat caaattgact aaggtcgttt tacctgaacc agtcccccct atgattgcga
     2881 cgatctcgcc cgacttggct tggaaatcaa tatcttccaa tgcaagtttt tctgctccat
     2941 gatatcgata attgacatga ttgaaggcca atgttgcgtt ttttccagca aaagaaactg
     3001 ttttaggatt ttcagggtca tggataccga ttttttcatc caacacttca ttaatacggt
     3061 cagctgaagc ttgtgcacga ggcaccatga taaaaatagc ggaaagcatc ataaagctga
     3121 tcaagatctg catcgcataa gtcataaatg caatcagatt accgacttcc aaagtcatat
     3181 ctgctatgta gtgtccacca aaccaagtga ttgctacgtt tgtaccgctc atgatcaatg
     3241 tcatcattgg catcatcaat gcgacgatcg tattaacttt gattgccgta tttgtataat
     3301 ctttattcgc taaatcaaaa cgattttctt caaagcgtgt cttatcgaat gctcgaatca
     3361 ctctgacccc tgtcaatcct tctcgaaata ccaggtttaa acggtcagtt ttcttttgca
     3421 tacttttgaa taatggaaca gcaaagtaca tgattccgcc gatcaaaata atcattactg
     3481 ggatgacaac taagaagatt tttgtcaact gatgatcttt ttgataagca agtatgctcg
     3541 cgccaatcaa cgtgattggt gcattgatca tcatacgtaa aaacatttgt gtaaccattt
     3601 ggatttgagt cacatcattg gtcgttcttg tgatcaaaga ggccgttcca tatttatcaa
     3661 acgcatcttt tgtcagactc tctgattttt tatagacatc cgtacgcaat tgcttaccca
     3721 gtttctgtga ttcacgagta gcaaaaaatg tatttgcgat agcagctaag atactgatca
     3781 aagaaaagcc gatcatcaca aaacctgtat gccaaatata atcgacatct ccttgcgcta
     3841 cccctttatc aataatattg gaggtaagtg tcggcaaata taaatctgcc agtacttgga
     3901 tcaccatgaa aactgcagct gcaattgctg aagtcaagga gatccgtttt acgattttta
     3961 gcatctagtt cccttctttc tatttatata ctccgttttt cagccaagaa agtttcaaat
     4021 tgaattcact gattgcttgc tctactgagt aatcttcaga tgttgaaaat aagcgatacg
     4081 aatgcgcaat tgttgtaaat acagtattca tcactaattg gatcagtaat tccaattcat
     4141 gatcattttt tactttcagc ttcgtccgat cgatcaattc aagcaactct tttgcatctt
     4201 gtttgtgttc tttatgtgga tcgtgaggcg ttttttggcg actcgtatga ggagcgactt
     4261 ttcttgaggc acggtaatcc atgttcataa acaagttacg ataaaaagaa gcattctcgc
     4321 cttccaaaat ctcataaatc attttagaaa aataggattc gaatcctttg aatagatcac
     4381 catcggattc tttcattagt tgtaacatat ctttagagct gtcacgtctc attgtctcaa
     4441 agtaataaaa ataaagatcc tctttatctt caaaatactg atagaaactg cctctaggga
     4501 tatccgctaa tttgacgata ttagcaatcg aagcttcttt taagggtact ctagaaaact
     4561 cgattctcgc agcctcgatt agtctttttt gtttttcttt aggcaaatgg aaaaatgtct
     4621 gtgtcggcat atggattctc ctttctttca agatgacaca ttgtcatatg acgctatgtc
     4681 attataacac ctcctacctg ttttgcaaga catttgcata gtttttttca ttatcatccg
     4741 atacattaaa aaagtgataa gaggaatcct tccatttgaa ttaatgagag ttgcccatta
     4801 aaatagccac atactaaaca aaggatgaga taaatggccc aatcaattag tgtccaagac
     4861 ttcaataaat tgcctctcga tgctgacagc atcgttttag atacaagaaa taccttagat
     4921 tacacaaaaa accacttaag ccactcgctt tctatccccg ctgctatctt gccaagacaa
     4981 ttaaaaaatc tagatccaaa gaaactttat tatattctaa gctatacagg caggcgatca
     5041 gaagcattag ccgatcaact tactgctaat ggttttcgtg ctgtttatat cattggtggg
     5101 atggaagctc ttcagtcgag tgttgcttga atattgcttg ttagattcaa aagaggctgt
     5161 gacaaaaaat cgtgtcacag cctcttttat accctgtctt tttttagtta tttattcttc
     5221 aaccttatca atatgacttg atagcctttt ctttttcgag taaactgatt ttgttagtca
     5281 tagttataac aatcatagca ataaaaggag aaggtaagca tatggcatct gttttagtag
     5341 tcaaaggtca tcccctaact gcagaagaat cgcgcacagt taaggcattg acgtcttttt
     5401 taacaagtta taaagaaaat catccagatg atgaagtgac tgttttggaa ctttatcgcg
     5461 atgatattcc ggaaatcgat gaagaattat tatcaggttg ggaagcatta cgtgctggtg
     5521 cagaattcac ttccttatca gaaagtcaac aacaaaaaat tgctcgtttc aatgaattga
     5581 ctgatcagtt ccttgctgct gataaaatcg ttatcgcaaa cgccttatgg aatctaaata
     5641 tcccaacaaa attaaaagct tggttcgata ccgtcaatgt agctggaaaa acgttccgct
     5701 atacagaaaa cgggccagaa ggattagtga caggtaaaaa agcactgcac atccaatcta
     5761 atggcggtgt atacaacgga caagactttg cctctcaata tgtaaaaggt attttaaact
     5821 ttgtaggcat cgatcaagta gatcagctat tcatcgaagg aatcgattat gaccctgacc
     5881 gtgcagatga gttgatgcaa aatgcattag ataaagctgc tgctttaggt aaatcatttt
     5941 aaaaattgag ataaatgcat acaaaagaga cagaggaaaa aatcttcaaa gcagcatttg
     6001 tgccttggat attttcccat ctgtctcttt ttgttattct ttctgctttt tcaacggatt
     6061 ttcttcataa agagaagaga ttgttgtgta ccattcaaaa acatgagtaa tcactacttt
     6121 agctgctgca taaacaggaa tccccaagat cacaccgatg attccgaaca atttcccaga
     6181 agtcagcaga actaataaaa tcgttactgg atggattgct aactgattcc ctagtactaa
     6241 tggagagatc aagcgtcctt ctattgtctg ctctactgca aaaacgatca gtactttgat
     6301 gatcatgaat ggacctgcta caatggctaa aaagatagcc ggaatcatcg ctaaaaatga
     6361 tcctaagtaa gggatcaggt ttaaaaaacc cgcaataatc cccaacgtga cagcatactc
     6421 taaaccaatg accgcaaaac caatcataaa catgattgcc acagcaaaag ccacagttag
     6481 ttgtcctctt atataagaag aaacttgact attcatttca ctcagcacat tcaacgtcgg
     6541 tttttgcatg cgtgtcggta aaaatttgac aaaataaggt gctaattgtt taccgtcttt
     6601 caatagataa aataagataa acggcatcgt cagcagagcc actaaaatag tcgctaccgc
     6661 gccgacaaaa cttccaagac tctgaactgt actcttagat atatcttgga tcatatcgcc
     6721 tgccgaattc atgaacttat cacctgctgt ttccaactgt tcgcgaaatt ggttgaacag
     6781 cgggtcccgc aaaatctcgg ttaatttatt atcaatcgta tctacatatt gagggaagtt
     6841 actgatgaag ctcactgttt gttcctgaat cttagggatg atcactacgc tcccccatgc
     6901 gattagtgca acaaccaaaa caaacagccc aatgatactg taaagccttg gtacttttcg
     6961 cttttcaaag taatcaacta ccggattcat caagtaatac aagattcctg ctaaaatgat
     7021 aggcagacct acgattgcta aaaattgcca gattggtgca aacaaatatg aaacttttgt
     7081 aaataaaaag acgatcagca atattaacaa tacaacaagt aaggctgtga ctacttgatt
     7141 atttaaaaac cagcgccaaa accacgatac cggtctgttc ttcttatttt ttccttccat
     7201 aattcctcct gttagttata aaaaatttgg cttcccaaac caatagcagg cagtctatgc
     7261 ggatgaagat agattccatt tgcaatttgt ccttcttctg gacaagcatc aaaaatcaat
     7321 gatacgtgag ctactgtctt taaattccca ttggccatcg gaccgacata atcgatcgta
     7381 tatacctgat catcaaaagc aattgttccg cctgctttca aagaaaaagg ttcgtctttt
     7441 gatacttctt gaatcaccga atattttcgt aaggcagctg ttgctgtttt atcgaacaaa
     7501 atcagcatgg gttcttcctt gtttattgct tctgtcccaa tttctgtaat ctttgcctga
     7561 atcattgcac tctctccttt aattgctttc aaaaacagta taacacattc tcattcttta
     7621 gccgtgtgga ataattatgt gatagaataa aaacgaaaac tatttcatta caattaggag
     7681 gaatcagctc atatgatcga aaagataatt ttaggaacct atacgcgtcg cgaaagtaaa
     7741 ggaatctata cgatcgacct tgatacagaa aaagaagaat tagccaacct ttcattagct
     7801 gttgaagaaa atagccctac ctatgtagca aaaagtaaag ctggcaatct ttacacagtt
     7861 actagtgtgg atggattagg tggtgccggt gcgtacgata aggattttca ttttttgaat
     7921 gcggtaacag agtctggcgc tcctttgtgt tatgtagcgg ttgatgaagc acgtcaatta
     7981 ctatacgggg cgaactatca taaaggtgaa gtaaatgtct accatatatt aggagatggc
     8041 gaactgaaag cagcagattc aatattccat caagaagcga caggtcctca taaaaaccaa
     8101 gatcatgcgc atgtccacta tacggatctg actcctgacc aacgattagt cgtatgtgat
     8161 cttggtacag atcgtgtgta tacttatgat gtgtccgaaa acggcaaatt gaatcttgta
     8221 actaccttca ctgcagagcc aggaacaggc cctcgccatc ttgtctttca tccaaatgga
     8281 caattcgctt atttatttgg tgaattagac agcacagtcc gcgtgctttc ttataataaa
     8341 gaaacaggtg cttttgaaga attacagaaa atatcgacct tgccagaaga attcgacggt
     8401 gaaaatggag gggcagctat ccgcatttca aatgatggca agttccttta tgcttctaac
     8461 cgaggacata actcgattgc tgtattcgca gtttttgaag atggttccca cattcaaaac
     8521 aagcaaatca tctcaacaga aggggatttt ccccgcgatt tcgcactaga tccaagcaat
     8581 aattttgtcg tgtgtgccaa tcagaacacc gataatctga cattatatcg ccgtcatcct
     8641 gaaacaggat tactggaatt actgaaaaaa gatgtctatg taccagaatg tgtctgtgtt
     8701 tattttgatc gttagtaaga aaaggagaat gaaatgaatc agcaagacgt attagacaga
     8761 ctacgggaag aactaaatat tcctttcttt gatgggaaaa tcgaagataa agagtatagc
     8821 gaagaggaat atcagaaact caaagccgat ttacagaact actttgaaca atatgtacag
     8881 aatgtagaaa actaatcagc tttccatact atctgaaaag aacatcagga caagactttt
     8941 ccgtctatcc tgatgttctt ttctacaaat aaaaaaccgc cgagatggtt agactcgacg
     9001 gaaaaggagt atttactcga ttttgagtaa gtacaaggtt gttgttggtt ataggtatgt
     9061 cattatcata aaggattttg atcactctat cataaaggta atattacatt tatattagat
     9121 aactctagtt tttattgtta tcaaagattt cttttatttt ttcaacaaca aattagtcat
     9181 tttttggatg gcagctgtca attggtctgt cgcttggtct tgttttgctt cagatgtatt
     9241 gaatagatct tcatctaccc ctgattcaag atcgatactt tggatcattt cttcacagcc
     9301 tgctacatat gaaagataag ctttttcaaa atttttatga atgcccattg cttttgctgg
     9361 tggacgcaaa gtactgactt tcataagcat tgcccgatat ttttttgttc cttcttcaaa
     9421 taacaggatg atctcttcaa gagtcgattt gtccagttca cttgtttttc cttcatcaat
     9481 tgcgtttctg atcacttcat atttcggatg cattccttct ccgattgctt ctgtttcctt
     9541 gacgatttga tcgatggact gcacataata gccaatattc ggtaacatgt tcgttttcct
     9601 actttctcca ttgttgttat tatttattct acttgttttt atcctcaaat gacaagtact
     9661 tgaaaaaatt taatggtttc tatacagctc gccattctta ttcgtgctca aagaaaccat
     9721 ctgctaaact atattgtttc cctgcgacaa tgtcatattg gatcaattga tattcgtcgt
     9781 aaatctcttg ttgcgagcga ttgaattgcg cttctttata ccactgtccg ttttgatagt
     9841 acagttctcg ttcaaacgcc ggaagttcct gttctaatga taaaagcagc tgataaaagc
     9901 catttgttgt ctgattcgtc tgttccatta gattcgctgc aaaataaaac ggactggtga
     9961 ttgcatcgtg agtcgtttgc ttttctaatt ctcctttact gtcgaacata agaaattgtg
    10021 tttcatgcaa tgtttgtttg tcattttttg cttggatcgt atctgaatag atccctggaa
    10081 gatgatcccc ccaaaaaaca actaaagtcc ttctagaaag attcttcaat tcttccgtga
    10141 actgcttcag tgccgtgctg ctataggaaa tatcttgcag ataattctct aagtcaagtg
    10201 tcccacttcc atctgaagtt tttgcaggat agtctagatt atcatacttt ccatcgtagg
    10261 gcatatgtgt ctgcatcgtg actaaatgaa tgaactgagg tgttttttct tccttgagaa
    10321 gtgtcattac ttctttgtaa gctgactcat cagaaatata tggattattc tctatcgtat
    10381 ccgtataggt catcgtacgc tcgctgatga actggtcaaa tcctaatgtc tgataaacat
    10441 cctctctttt atacatcgaa gtattgtatg gatggatcgc tgtcgtctgg tatgattgtg
    10501 cgtttaacgc tgaaacgata gaaggaagct gatccatttt tggtacaagc atcgtgtaag
    10561 gggtggtgag ttgcgcatta aataacgcca tagaaaaacc agtcaatgct tcaaattcga
    10621 tatttgctgt tccaccgcca tagttttgag aaagcatatt gccactatat gtttgatcag
    10681 ctacttcata ataatctgcc aatggctcac cagatacttc tacgccgttt aatcgactag
    10741 gatctgagaa actttcactc atcacgaaca cgatgttcgg cgactcttcc tctacagttt
    10801 tatttttttc atcggctagc ttctggtatt tttcagtgat ttctttgatc ttttctttcg
    10861 aatatccttc aggttcatcc attggttcta ccttcagatt gtacaaaaac ccaccgataa
    10921 aaccagtgtt atagtagttc attttctggc tgtaaggtat ccatagtgcc gttttattat
    10981 atgcttttcg caacaaatta tcgggattgt tgaaattact gatataccct agcagtccaa
    11041 ttgccacaag cagtgtcgtt aatcggatca attggaatcg ccttcctttt ttcaggcttc
    11101 gaaacatgta ccagcaaaac aatcctatca cggttcctgc ggcagctaag atcactgtaa
    11161 acagcatagt gccggtcata tctttcagca atccgatttc agtgatcatc ttcaaatcgt
    11221 ctggataaat cggttcttgc cgataactca ttttcatata atttgcaaaa cctaatacac
    11281 cgatggctac gacatacgta agggaaccta aagggacaga tcctgctagt gcaatcagaa
    11341 aaataagaat aatcagcaag acgagacagg ctaagaagaa tttttccgta tgccaagaaa
    11401 aagcaaattt caacgcaagg tctacggata gatcattttg acaccactgc aaaaataaat
    11461 tactaaaaac aacaagaaaa aagatactga tgattgctgc tgttcctttt aaaatctttt
    11521 tctgtttggt cgaaagtctg cttatatatc ttttcaaatg cttgctcctt catttctatc
    11581 aataaaagaa tgttgcttct cttattttag ttgtacgaaa ttcgaaagta aagaacggaa
    11641 agaagaatta atgaaatcca aatattctct ttctttatgg cctttctggt ttctttaata
    11701 agcggacctt tcgtactcca gaaatttttt ctagctgttg tttcacttga ttgagctgtt
    11761 caaaatcagt actgtctatg tcaatcaata tgtagacatg ctcattctta tggttacgcg
    11821 atatatctgc gatcgctagc tcgttctcat tcagcagaga aaatatctct gctaatatat
    11881 tggttttctt ttgataaaat atagtgaatc gaaacggcgc ttggaaaaac attcgtgcgg
    11941 atggataatt gaccgcttct ctaaccgtac cgaacaaaag ataatctttt aaggcttcaa
    12001 ctgccaaacg tccgctgtct gccaaagctt cctgagtcga tcccctagat gaggcaacat
    12061 aagtatacgg tcattttcta agaactcttc ttctggaaaa tcagtcaagt atttagccag
    12121 atgttgtttt tccaatgctt gcataacagc atatttatca acaatttcac ttcttcctac
    12181 attgataagt acagcatctt ttttcatttt ttctatattc gcctgatcga tcaatccttt
    12241 tgtatcttct gtcaacggca gcatgactac gatgtaatcc gaggtagaaa gaactgtttc
    12301 taaatctgct tgccgaacat aatccaactg ggcatcgcgg atagaataac ccaagacatc
    12361 catccctaag ctatagcaac ttagcgctac ttttgtgcct atcgctccaa gaccaagaag
    12421 accgatggtt ttgccttgca attctcgtcc cacataagca cttcttttgt tttctgcctg
    12481 ttctaaaata ttaggacctg ttagtgtttg taccatacga cttgcttcga ttatcggacg
    12541 ggaagataag agcaaacagc acaaaacaag ctcttttact gcattagcat ttacacctgg
    12601 tgtattcatg acgatcgtcc cgttttcaga agctttttca acgttgatcg tgttcacccc
    12661 aacaccagct cttgaaattg ctagcaaatc tggtgtaagc cattcatctt tcactttcgt
    12721 actacgaata actattcctt cggctggcaa atcatctatt attttgaaat attccccttg
    12781 taacttttct atctcttgtt ctggaatagc atcaatcaaa tgaacgtgat acataaaacc
    12841 ccctccttac taacaagtat ctcgaaattt ctgcaattag acaactgttt accatttgac
    12901 ttcctagaag caaaaagagc agttagagca gagtaggctg agtgataaaa ataaggctat
    12961 gacaagttac tgccataagc cttattttcg agagcaaaat attgagggtg agatatcttg
    13021 ataaatggtg ttccgttagc tgacattgat aataagacta aatttcaaaa aagttgaaaa
    13081 gcaaatttcg tcaatctctt cttatttctt aaaactaagt ggctttttca caacctcttt
    13141 ttatctaata accactgttt ccaactcaac taattttgcc cacgtttcaa tttgatctgt
    13201 tgttagattt agcgagacaa cggtatgatg accgccacct gcctgaatcc atgaatggac
    13261 accttcatgg aaattcggtt tagttttcca taacacacgt gcaacaggta aattaggtgc
    13321 ttcagtcgtt ggttcaaagg cttctacttc attgatcagc agtttataat gcgtaccgaa
    13381 atctgccatc gatacgacta ccccttctcc tgctttccca tcaaatacaa gacgcgccgg
    13441 atcttctcta tctcccattg ataaaggaga aacaacgatt cttggtttcg tcgcagcaag
    13501 cgtcggatct acttccatca tatgggattc caagattgct tcttggccac tagctagctc
    13561 gtaagtataa tcttccatga atcctgtatc tttccctcga gccatgattt tcagcaaccg
    13621 atcaatcgct gcagttttcc agtcgccttc cccagcaaaa ccgtatcctt ctgccatcaa
    13681 acgttgtaca gctagtccag gtagttgttt cattccatac aggtcttcaa aattagtcgt
    13741 aaaagcgtta tagcctcctt cttctaagaa acggcgaata ccgatttcct gctgagcttg
    13801 tacttttaca tgttcctccc atgtcttttc ttcataatca ccatagtcga aggtatacaa
    13861 ttccttgtac tcttcaaata attgatcgac ttcttcgtct gatacgcgat cgattacttg
    13921 tacaagatct ccgataccaa aataatcaac agtccaacca aattgaatct gtgcttccac
    13981 tttgtctcct tctgtgacac ccacgtttct catgttgtca ccaaaacgag ccacttttat
    14041 tccaaaactt tcattatagg ctactgcaac atccatccaa tcagcaatct ctttttggat
    14101 ctcaggtcgt ttccagtagc caacgacgat tttattttgt ttatttaatc gagcattgat
    14161 gaacccatat tcgcggtcac catgagcgga ttgatttaaa ttcatgaaat ccatatcgat
    14221 cgttttccaa ggaatgcttt cgttatattg cgtagctaaa tgaagcaatg gtttttgtag
    14281 aagctttgtc ccgcggatcc acatttttgc tggtgagaaa gtatgcatcc aagtgatcac
    14341 acctgctact tcttctcgat aattgacctc tttcatgatt tttgtgatcg tatcagcagt
    14401 aactgctaat tcttgaaggc ggattggata aggcaattgg ccattttcat tcagttcatc
    14461 gaccatttct tgtgcatgtt tctttacttc tcgcagtgct tcttccccat ataaatgctg
    14521 tgatcctaca acaaaccaaa attctttttc tccaatattc aacataatta gccactcctt
    14581 ttatttgttt tgtccgtaat acgcattttt tccgtgtttt cgtaaataat gtttatctaa
    14641 aatccgttga ggcagctctt ctgaaaatga attgagctgt ctggtaaata aattcatctt
    14701 gcatacttca tctagtacga ctgcgttcat taccgcactt tgcgcatctt tcccccaagt
    14761 aaatggaccg tgtccgtgta aaagtacccc tggaattgct aagggatcaa ttttgcgttc
    14821 tttgaatgtt tctatgataa cttttcctgt ttcatattcg tacccgctgt cgatttcctg
    14881 ttgtgtcaaa aatcgagcac aaggtaccga tccataaaaa gtatctgcat gcgtcgtccc
    14941 catcgcagga acatccaatc ctgcttgtgc ccagatcgtc gcccatgtcg agtgagtatg
    15001 gacgattcct ccgatttgag gaaatgaacg atataaaaca gcatgagtag gcgtatccga
    15061 agagggattg agtttacctt caatgatatg attgtccaag tccacaacga ccatgtcgtc
    15121 tgctgtcatc tcttcataac tgactccgct aggtttgata acgaaatatc gtgtttcagg
    15181 atcaaaagcg ctcacatttc cccatgtata tttgacgagt ccgtgtttag gcaagtcaag
    15241 atttgcttgg tatacttctt ctttcagttg ttccagcatt ttctatcact cctttttctt
    15301 gcaattgatg aatcgctgtt ttttcaatgt cgatcccctc acggtaacgt ctcataaata
    15361 tctgatagcc tgctatttct tctgctgaag gtgtgatggt gattccttgg tcttgtccaa
    15421 acacgtcttc tgccaagaag ttttctaaag acttcccatg tcgatccatc atataggctg
    15481 ctaataacgc gattccccac gctccacctt ctccggctgt gtccatcact gtaactggtg
    15541 cctccatagc agatgctaga atccgctgtc caacttctgg tgttttaaaa atccccccat
    15601 gccccactaa acgatcaatt tggacattct cagatttcaa tatatccatt ccgattctca
    15661 ttgcaccaaa agcactggct aaatggatcc gcatgaaatt cgctaaatca aaacggctac
    15721 ctggtgtacg tacaaataat ggccttcctt catttactcc tgtaatgttt tcaccggaaa
    15781 aataaccata agaaagtaat cccccgcaat ccgtatcgcc ttctagcgct ttgttgaata
    15841 ataccgtgaa taatttatct ctgcttatct ccatacccaa agaattggta aattcttcaa
    15901 aaatactgac ccaagcattg atatccgaag agcagttatt cgtatgaacc atgcctacta
    15961 gttctcctga aggtgtagtg accatgtcga tttccggatg gacattttct agttcttttt
    16021 ctaatacgat catagcgaag gcggaagtac cagccgaaat gttccctgtc cctttggcta
    16081 cactgttcgt agcgaccata ccggttcctg catccccttc tggcggacaa accgggattc
    16141 ctggtctcaa atttcccgta gggtcgatca gataagcccc tgattcgctt aacttgccag
    16201 cttcttctcc tgctactaga actttaggca aaatgtgatc caagtcaatc gctacgtgcg
    16261 ctttttcgat taactgacca aaaatatttt tcatttcttg atggtaggtt ttcgttgaag
    16321 gatcgatagg aaacatgcct gatgcatctc ctacgcctag tactttctca ccagtaagct
    16381 gccaatggac ataacctgca agcgttgtca aaaaattaat ttctttcaca tgttcttctt
    16441 tattcaaaat agattgatac aaatgagcga tactccatct ctgcggaata ttgtattgaa
    16501 atttttccgt taatattcgt tctgcttctt cagtgattgt atttcgccaa gtacgaaatg
    16561 gtactagtaa ctgttccttg ctatcaaatg ctagataacc gtgcatcatt gcactgaacc
    16621 caatcgaccc gattgtcgta agattctcgc catagatttc gaatacttct gctgccattt
    16681 ttcggtaact gacgcgcagt cctttccaaa tatcttctaa tgaataggtc cagataccat
    16741 tttctagttt gttttcccac tcataactac cagcggcaat aggagtaaaa gatgaatcaa
    16801 tcaatacagc tttgatccta gttgatccaa actcaatccc taaagatgta cgaccatcta
    16861 tgacatctaa catactttgc gcatttactt ccttcataat gatttaactc cctccttctc
    16921 gtcaaacctg atcaaaccgt ctttttagta gcgcttacaa tgattattgt atacttttgt
    16981 acgtacatgt caagcagtta tttacaagaa tacaataaaa aacacttgtt ttgtacgtac
    17041 ataagttata aaatgaaatt gcttacaaaa tctgatcaac cgccttctcg aaattctaga
    17101 aggagagaat acttatgaaa aaagaaaaaa aagtttcctc atcgtttatt tatttttttg
    17161 gcgcatttgg cggcattcta tttggatatg atattggtgt tatgaccggc gccttacctt
    17221 ttttacagca tgattggggt ttggcaggta aagcttcttt gataggatgg atcacgtctt
    17281 cggtcatgtt aggtgcgatc cttggcggct ctttatctgg tcttctttct gataagcttg
    17341 gacgacgaaa aatgattctt ctttctgcac ttatttttat ggctggttct gtcctttctg
    17401 catctgcccc tcacaatggt tcttattttc tgattgcagc aaggattctt ctaggtttag
    17461 ctgttggcgc tgcatctgcc ctagttcctg cttatatgtc tgaaatggct cctgctagac
    17521 taaggggaag attgtcaggg atcaatcaag tgatgattgc ttctggcatg ctcctttcct
    17581 atgttgcaga ttatttgcta aaagggttgc ctgaaacgat ggcttggcgc gtgatgttag
    17641 ggctcgctgc tgtccccgcg ctgattttat ttttcggtgt tttagctcta ccagagtcac
    17701 cgcgttttct tatgcaatct ggccgcttgg aagaggcaaa aagagtattg aactatattc
    17761 ggacaccaaa agaagctgaa caggaattcg aacaaatcca gctgaatgtc aaacaagaaa
    17821 agacaaccgg aacttcttgg catactttgt ttttagaaaa atatcgttcc ttagtcattg
    17881 ccggtattgg tgtagcagta ttccagcaat ttcaaggagc taatgctatt ttttactata
    17941 ttccgctgat cgtagaaaaa gcgactgggc atgcagcgag cgatgcattg atgtggccga
    18001 tcatccaagg aatcatttta gttgctggtt ctttgctctt tttggttatt gcagacaagt
    18061 tcaatcggcg aactttattg aaaataggcg gtagcgtgat gggactttct ttcatcctac
    18121 cagctgtttt aggaactgta ctggatgctc atacaaattc gttgttgatt ctcttgtttt
    18181 tatgtattta tgtcgcattt tattcttgca catgggctcc actgacatgg gtaatcgtag
    18241 gcgaaatatt cccactagct gtccgcgggc gagcatctgg cctagcctct tcttttaatt
    18301 ggattggttc tttcctagtt ggcttgcttt ttcctgtgat gactgcttct atgtctcaag
    18361 aaatcgtttt cggcattttt gggatcatct gctttttagg ggttttattt attcaagaga
    18421 tcgtaccaga aactcgtggg aaatctttag aggaaatcga acaaagtgca tctaaaaaaa
    18481 cttatcctaa acgtatttct atccatcatt cttaaagagg ttgtgacaga agtggtcagc
    18541 ttcaagaaat aagaaggaac cgcttagttt ccagtcacaa ggaacaattt caaaaaacag
    18601 cttctcatgt ttgatgaata ttgtgacttg tgaccagttg gtaggagaac accgtttagt
    18661 ggagaggtgg tgaaagaaac gttcagcctt gagcgatgac aaaagctctc acaaacattg
    18721 cgacgagtaa ccgtaggagc aataagaggc ggtaaaaacc cgtctcttat ttttcgtttt
    18781 ctttcactgt ttcccgttca actagtacag gttcatagag aatatttggc tgtgcctgtc
    18841 ctttttcaat cgttgtgacg atccaccgtg cggcatcttg tcccaacttt tcttttggat
    18901 gcgtcaatgt tgtcaatttt ttattcccta aatggcttaa agaagaatcg tctgttccta
    18961 cgatcgatag gtcatctgga atatgatagc cattttctgt caacttatct agcattaaac
    19021 tagctatttg atcgttatag caaatgatgc catctaaagc ttgttcttct ttcaaccgtt
    19081 gtactgtttt ttcagcgatt gtttctcgtg tttccgtggt gaaagtaatg atatcttccg
    19141 tcaaaaaacg cacattatac tgttcacacg cgctgataaa acctttcatc ctgtattttc
    19201 cttgaagatc gtcgattttt gtgatgaaca acagacgctg atgtcctttt tttatcaaat
    19261 attctgctgc cataaaaccg actttcacat catctaaaca aatataagag gcatttaact
    19321 cttcataagc agcattgatc atcaccatcg gaatgccttg ttctctcaaa gcaacataaa
    19381 gtgctaagtt tgggttatac tgattacttt tcgtaggctc aacgatcaaa ccatctaccc
    19441 cataagcaat cattttcttc aaacactctt tctccaattc gtgatcgtta ttcgtactgg
    19501 ctaaaagcaa tgaataccca gattctcgta attcattttc gattcctcgg ataatcgacg
    19561 gaaaaatata atcagagaga tatgtggtga tgacaccgat cgtttttgtt ctgttcaatg
    19621 gtgttttttc tttcttatag ctgtcatcta catatgtgcc cgaccctttt tctttacgca
    19681 gatagccctc atttaccaac acagcgattg cttgccgaat cgtatgtctg ctgacgtcat
    19741 atatttcttg cagcttgaat tctgagggaa tggttgtatt tacttcgtat tcctcacgaa
    19801 ggatcttttg ttttatctct tctgcaatat cttgatattt tgccatttgc cttgcccctt
    19861 tttatttgta cgtacatata tcataacgag tctgcaaggt ttattcaagc aaaaatcaag
    19921 gtttcttgtg ctcataaggc atacggaaca ggttcaccaa attctggaaa tccttgctca
    19981 ttccacgtaa agcattgcgc gttcgcgtgc cgattaggat tgtctaacgg atcccctttt
    20041 tggttcttct ctggtcgagc atgatagatc aaagtatcaa agcacccgtc ttctgaaacc
    20101 gtaaacgagt tgtgaccagg accaaattgc ttattttttt cagaagaaac gaatactggc
    20161 tccgataatt tatgccatga ttcttttaat aaaagattct tgtgctcatc agcccacagc
    20221 aggcccatgg catagttttc atctgttgca ctaccagaat acgtaatgaa tattttccca
    20281 ttgcgagtaa ggactgctgg accttcattt actgaaaaac cccgtttttc ccattcatac
    20341 tcaggtatag aaaggaggat ctgcttcccc tttaacgtcc aaggattatc catttcggat
    20401 agataaagat tagaattccc agtaatttca ggatcttgtt gggcccacac ataatatagc
    20461 tttccttgag aagagaaagt tgttccgtct aaactgaaag tttccctttt cgtttttatt
    20521 tgtccctttt ctatccaatc tgtattcatt ggatctatat gctgattttc aagtacgaac
    20581 atgcggtgat gatgagattc atcacgtata gttttatgat tgcttgcagc aaagtaaata
    20641 taccattttc cattgatata atggacttca ggtgcccaga tcaattcact catcggtcct
    20701 tcttcatgag cctgccatac aatcaggctt gcagcatgtt ctaattcatt cagtgacttt
    20761 gcccttctta attcaatcac ttggtagcct ggaaccgatc ctgtaaaata ataataacca
    20821 tctgtatgtt tatataccca aggatctgcc cgttgccgaa cgataggatt attataaagt
    20881 gtcttcatca taacaaattt cctcacattt tctttattct aattacattc caagagtatt
    20941 tttctatccc tacatttaat tcgtcatgtt tttctattga aaaatagttt atttcaggtt
    21001 ttattttttc tggttcttca cgtgtatttt tgtccaacag atcgctactg gttaatgtgt
    21061 agtgctctcc ttgatctagc aaattgaaat catgttcaat cgttatcttt tgttgttcat
    21121 ttgtgcgatt gatcaagaaa atagtcagct gattgccgtt atctacgatc acactgtcca
    21181 cataaggaac attttttatc ttttcacaat cataaacagg gcaaatgatt tgttgtttca
    21241 atacttgacc tttagcatat ttcgataagt gttgcatcac ataataagtt ggattcctcc
    21301 atgcttgtcc tttagcatct gtcagtatta aaggtattgt gtttactaac aatgattgac
    21361 aactaatctt tacgcgatct gcgtgtcgta aaatagccag ccctaatgaa ccaaataata
    21421 atgtatcttc catagtaaag taacaccaat cgatgggact accgacttca aaatccctat
    21481 gtcttttttc cggttgggca tgtacattcc attcatcaaa cgctagatac attgttttct
    21541 cacttctcaa atatcctttt acataatcac aagtagcaac gatttcttca atttgacgat
    21601 cgaatcgata agcttttgca aggtatgtcg ctgtatcatc acgctcattt ttaggaggtt
    21661 tagtcaagtc ttcttcatca tacttatcaa tatagttatg caaagctaaa taatctacat
    21721 tctcataagc ttcttctaat gcgatacgat cccattcagg gtacgatggt aaacgtggcg
    21781 tagagcttcc aactaagatt gtttcaattg aatcatccac taacttcatg acttttgagg
    21841 cttcatttgc taacctacca tattcataag cactcttagc ccccacttgc catggaccgt
    21901 ctagctcatt ccctaaacac cataatttaa cgccaaaagg ctttttttgc ccatttttta
    21961 ttcttaaatc actccagaag gttccttttg gaaaattaca atattctact aaattttttg
    22021 cttcatcaat tccttttgtt cctaaattca ccgtgaatat cggtttcgct tgtacatgac
    22081 tgatccattt aaaaaattcg tggagtccaa aagaatttgg ttctatacct cgccatgcta
    22141 aatcaatttt ttttggtcgt tgttctttcc tacctacagt atccacccaa tcataaccag
    22201 atgtaaagtt tcctccagga tagcgaatga cacctaattc taattccttt acataagaga
    22261 ggacatcttg tctaaacccg tcaccatcag ctgtttcatg gcccggttca taaatccctg
    22321 tatagacgac acttcccata tgctcaacaa atgagccaaa cagccgagaa ctgatctctc
    22381 ctaccgtaaa atcctctctg atttttactt tcacttcttc gtccaacagc tttccctacc
    22441 tttcatttcc tatagtcaag ataatagata caagtttcca tacgccacca gcaaagataa
    22501 aaataaaagg agggaaaaga aatatgagca gtacaaatcc taataacaat acgcaacaaa
    22561 gaatatttct caaaaaatca aaaaatactt tccatgcact ttgttcaaaa atttgtaaaa
    22621 atgtgatatc tttgttttca gaaatcacat atatccagga taaaagaaac atggaataaa
    22681 taagtaaaac tacatatcca ctaattgaaa gtacgattgt ctgttcttct aataattgat
    22741 taacaagaaa ataaataatg atcgttaaca gactaaggaa caagttctta ccaaaatgtt
    22801 gctttattcc ttgaaagaaa aaataaatga tatttcctga tccctcacct ttccattgcg
    22861 ccattacata aaaaacagca catgtagcag gcacgatagt aataacaggc aaacacacga
    22921 ttacccagag aatacctaat aagatgtaat cagaaaccac aatcaactgt ccataaagtt
    22981 tagtctcaac tattttcatc ttcctcactc tttcattcca gacatagctg ttccttgaac
    23041 aaaatatttc tgtgcaaaaa tataaaccac tagtaatggc agcattgaaa taaccgttcc
    23101 agccattaca ggtccataaa aagaaatgtt ctgccctgta aataaagcta accctgctgg
    23161 taaagttctc atttttgaac tacttgtcaa tatcaatgga taaagcaagt cattccaact
    23221 attcatcagc gtgaaaatcc ctaatgataa aagagtaggt ttgctcaatg gcaacatgat
    23281 tttcaaaaaa atattaaact cacttaatcc atcaatgcgt gctgcctctt ccaaagaatc
    23341 tggtaaagta ataaaaaagg aacgcatcat gaagatacca aatgcagttg tcatacgagg
    23401 aatgatcaaa cctgcataag tatcaagcat gccaagcaaa ttgacttcaa taaatagagg
    23461 aatcatgaag acttggaatg ggatcatcat tgtcagcaaa acgaaataga acaaaactga
    23521 ttttcctttg aaacgcatac gagcaaatgc ataccccgca agagaatcaa agaatacaga
    23581 agtgatcact gtccctccag caaaaatcac tgtatttttg atgtaatcta ataaagggat
    23641 cgttgtccaa accttaatat agttatctag ggtatagcta tctgcaaata ttctaggcgg
    23701 aaatgagata atgtcttttt cgtgtttaaa agaagaaata atcagccaca aaaaaggaaa
    23761 cgcaataacc aacaatataa ctagcatact aatcgttcga atgatttttt taccactaac
    23821 tgcttttcga ctattcacag taactgtaat cgagctttct ggtgccatac aggtttccct
    23881 cctatttcat ttgtttttct ttccgtgaca tgtacacatt agtggagata gctatagttg
    23941 caacaatgat aaacaaaacc gaagacagtg ctgatgcata gcccaattca taaggtgctg
    24001 taaatcctcg actgtaaata tattgaacag ctgtttctgt cttaaattgt gggccaccag
    24061 cggttgcaac atatacttgg tcaaacactt gcatcgaacc aatcagattc gttaaaatac
    24121 aaaaacctaa ggagggaacg atctgaggta gcgtaatgtt aaaaaactgc tgtcgatttg
    24181 ttgcaccatc catttgagca gattcataca aagagggaga gattccctga atagcagtca
    24241 agagaatcgt catagtaaca ccaaaattct tccaaacagt catgatggct accgtcggca
    24301 tagcaagggt tggatcgcga aaaaattgag ggatcggcaa gccgacttgt gaaaacaagt
    24361 aaggaatcgc ccctacattc ggatcaagca acatagaaaa aataatcgca attgacgtca
    24421 atgaacaaat aactggaatg taaaatgtcg aacgacaaaa acgattgaat ctggtatttt
    24481 tagataatgc tactgctgct aataaaccaa cgataatttg tgttggcgtt tcgagtacgg
    24541 tgaaatataa agaatgaatc aacgaattaa ctgctcgttc atcactaaat atacgtgtga
    24601 aattttcaaa acttacaaaa tttcttgatg taaagaaaat attcaaatct gtaaaactaa
    24661 tagcaaatgt tcctaaaagc ggtatgacag taaataataa taaaactaaa aaagatggag
    24721 ttaaaaacaa atacgcagca cgatcaggac gattccaata tttggtgaat ccgttcatat
    24781 agtccacctc atctttcatt ttgataaaat atacaatctt ggtttaaacg aatctgaata
    24841 agatatccga acaatcgctg tgatttttgc aataacacct atctgcaaat actaggtcga
    24901 tcattcagat atctgtatct tgccaacagt ctatcctgta taaagttctg tactattttt
    24961 gcagtaattg attgatggca tcatctgcat cgttcatgag tgtctcagga tcttctcctg
    25021 ctaataattt ttcaatcagt ggattgatga tatcgttatt gatcgcagag atttgggtaa
    25081 aacctggtaa atatggctct gcatagtcca tttgtttcga taattcagat acaataggat
    25141 cattttttac ttcttcatct tttgctactg aatccaagta ggcaggaaaa ccattttcga
    25201 tactccattt tttaccaatt tcagttgtat tccaatattt caaaaactca tagacagctt
    25261 cttttttatt attatctgta cttgccggaa tggcatatcc tacgccatct aaaatagctg
    25321 tttttttgtc tgaatcactc ccttgtggta aggtagtcac attataatca atctcgtttg
    25381 ctttcaatcc gttatttaac catggcccat tgatttcaat ggctagttga ccagcattca
    25441 ttaaattgtc catttcggcg ccagaaatcg attctggacc agtcttgtct acatggatca
    25501 ttttttggat cgcttttaac gttttaaggt tctcaggaga cgcaaattca gacttagtat
    25561 aatcatcgtt cactaattta ccgccatttg ctaacatcca gttatataac ggtgcagttc
    25621 catccttatt gaagacaaaa cctgatacat ttttactact atcagttaat tttggtgcca
    25681 tttctgtcaa ttcttcccaa gtagtaggtg gttgttcagt atctaatcca gcttgtttaa
    25741 acaaatcatt attccaatac atatacatgc cttgtacctg catggggaca aaatactgtt
    25801 taccttctac ttcacctaat tcaatagccg tttctttaaa atcagattta tctactccat
    25861 catattccca gaaatcgtct aatggttgta ccgctccgtt ttctacatac tgtgcaaaat
    25921 ctggataatt taatgcaata aagtcaggtg cttttttaga agaaatcgct gtaggaagtt
    25981 tttcattcaa attggcccaa gtcatgatat ccatttcaat tttgatgttt ttatcatttg
    26041 ttttattaaa ttcattaacg atttcttgca atatttcacc atcagatgca gtaaacccat
    26101 tccaaaaagt caaagtcact tctttatcag aatcagattc tgctgaactt ccgccaccgc
    26161 aagctcctaa aatacctgtt gcagctacca acaaagagcc aattaaccat tttttacctt
    26221 tcattttttg ttcctccttc atctgataaa cgacatctga ccacattcca agatagcggt
    26281 ttcaataaac aattgatttt cccatcttca gcttttacat ttgttgaatg acttggtttt
    26341 acttgttcac ttttaggaag attagttgct tttgtatcaa atccactcat ttcagaaaaa
    26401 tcaatcactc cctctaatga taattcagac aagtgaacag ttagattcat ttcttcttct
    26461 ccacggttaa ctgcaaatat gacaagttct ttgtcattta ttacggctat actttctaaa
    26521 tacggcactt cttcaaaatc ttccgtcgca tagtttgctg aacgaatttg tgggcttaac
    26581 acctctcctt gtccatacac agcagcttgc ataaatggat aatagatcgt ctgtctccaa
    26641 gcttctccgt ttgtttctgt cctgattggt gcaataacat ttaccaattg agcaagacaa
    26701 gcaatcttta ctctatctgc atgtttcaat aaagtgatta atagacagcc taatagtaat
    26761 gcatcttcaa aattatagtt atcttctagt aaaggaggag caatctgcca aggcgctgct
    26821 tgctcatctt gttccgctga atgataccaa atattccatt catcaaagga caggttgatc
    26881 tgcttcttac tatgtttctt cgccttgact gtatcgcaca tcgctgtcac ttcagaaatg
    26941 aaccgatcca tgtctaagga acgtgcaaga taatgagaaa gatcattttt ttggttgcca
    27001 taatattgat gcagagacaa ataatctatt tgatcgtacg cttgatcaag aactgttaac
    27061 tcccaatcac caaatgtagg catttgccga ttcgaacttc cgcataaaac cacctcaatt
    27121 gaatcatcta cgagtttcat cgccttagcc gtttcctctg ctaaccgtcc atattcttcc
    27181 gctgttttat gtccaatctg ccaaggaccg tccatttcat tccctaaaca ccatgtctta
    27241 attccaaaag ggctctcttg accattcgaa cgccttaaat cactccaata agttccttta
    27301 ggaaaattac aatattcgac taaattacga gctgcatcta ctccacgagt acccagattg
    27361 acagccatat tgatttcggc ccccacatgc tgacaccagt tataaaattc atgaatccca
    27421 acttcattcg tttcaattgt ccgccaagct aaatccaacc ttctaggtct atttgctatg
    27481 ggcccaatac tgtcttccca acgaaatcct gacacaaaat ttccaccagg atatctaatc
    27541 atgggaatgt tcaattcttt taccaagtga atgacgtctt ggcgaaatcc acttttatta
    27601 gctgatggat gatctggctg ataaatccct tcatatactg ctcgtcccat atgttcaata
    27661 aatgaactgt acaaccgcgg atcaactttg cctacacgct tgacactact aatcaacatt
    27721 gtggcttcca taactgacct cctttaattt atacatgaat aatacacctc gttgaaagcg
    27781 ttgtcaataa tataaatgtt aaacttactt attttttatc gattttaatt aaccaaaata
    27841 ttaataatga ttaaaacaaa taatttaata taacttttat taacaaatat gttaatatat
    27901 aagaaaaacc ttttaagagg tgatatatat gcaactacaa ataaacgaag aatccttacc
    27961 ggtatatgaa gcattagcta gtaaaacaag gatcaagatc atccagctac tttccaaaaa
    28021 aaagatgaat gtcaaagatt tggcaaaaga acttggagtg agcagtgcta tcacgacgat
    28081 gcacgtgaaa aagctagagg aagcaaacat catcaaaaca gaaaaagtag gacaacaaaa
    28141 aatttcgagc cttcgtgtcg ataaaatcga tatcagtttt ccagaaaaaa tattcaatgc
    28201 ttttgatacg aaagaaacat cgatacctat tggtcactat acaaattatg caattgaacc
    28261 aacatgcggt ttagctacga tccatgattt tatcgggaaa gtggatgaac cacgctattt
    28321 tatggatcct cgaaggatgg atgcccgcat tctctggttt accagcggat ttgtcgagta
    28381 tcaggcacct aattttttaa atacagagga tacattggag atgttggaag tttctgtgga
    28441 aatttcttct gaatttcctt tttcaaatga caattggcct tcagatatca ctttcagcct
    28501 aaatggtgtg gagctaggaa catggacgag ccctggagat tttgctgata tccgcggtaa
    28561 atatacgcct gattggtatc cagataatct taatcaatac ggcttgctga agacgatccg
    28621 aattaccaaa cacttgacga atatgaatgg agaacccttg tcaaacatca cgatcaacga
    28681 catccctaaa gagcaagaca cttggcattt gcgaatcgaa gtgaaagacg atgccaaaca
    28741 tgtggggggc tgtactttat ttggtaaagg attcggtaat tacgatcagg atatcaaatt
    28801 aaaagtttac tacagctgat atttttcttt tctattttat aaaacaaaaa cagccaatcc
    28861 ctatgaaggg acggctgttt ttgctttatt gttatttcca gaaatcatcc aaaacggaaa
    28921 ttggcaaatg tcgtttatgt tgtgtcttgt tccaccatgc ttcgattttt tcttgtgctt
    28981 gagcgggaac ttcttttcct tctagataat catcaatttc attatatgtg acacctagtg
    29041 cgacttcatc tgcaatcatt ggtttcccat cttcaagatc tgcagtcgga atttttgtgt
    29101 ataatttttc cggtgcattc aatgcttgaa gcaattgttt cccttgtcgt ttgtccaaac
    29161 ggaataatgg caaaatgtcg gctccaccat caccaaattt cgtgaagaat ccagtaatgt
    29221 tttctgcagc atgatctgtc cctaatacgg ctcctgctct ttctccagct acggcatatt
    29281 gcgtaatcat acgttgacgt gctttgatat ttcctttgtt aaaatcgctg attcccacac
    29341 ctgcttcgct taatacttgt acttgtgcat caacagctgg tttgatattt actcgcagac
    29401 taacatcggg ctggataaag tcaagagcag cttttgcatc ttcttcatct gcttgttcac
    29461 cataaggaag acgaacagcg ataaattgat agttttcatc ttttgtttct tcacgcattt
    29521 cttccatcgt tagttgcgcc aaacggcctg ctaaagtaga atcttggccg ccgctgatac
    29581 ctagtacaaa agttttaaga aacggatatt ttttcaaata tgctttcata aagtcaatac
    29641 ttttacgtat ttcttctttt ggatcaattg ttggtttgac acctaattca ttgataattt
    29701 ctgtctgcag gctcatttat tctcctccta tgcttctgta tgaagttctg ctacgctttt
    29761 tttcattcgt tccatgatag ccattttatg gttccagcat tcagtagaca gatcgactgg
    29821 gtatttttgc ggattcaagt ctcgtttata ctcttcccat agtgaatcta gattttcttt
    29881 tgtatattct ttgatttcgt ttagtgcagg taattcgtaa actctttttc cttcgataaa
    29941 gatatcttgt aaaactgggc gagctgtaaa gtctcgaaca gttttattga taaacgtatg
    30001 cactggatgg aacatgaaga tagcttcttc ttctcgaggg tcttcatccc ataatgtcac
    30061 gtagtctcct tcagatttcc catcaaaatt tcgagtgatg cgccacactt gttttttccc
    30121 tggagtagtt actttttctg cattgcttga taacttgatc gtatccatca tttttccttc
    30181 atcatcttcg atcgatacta gcttgaatac tgcaccaagg gctggctgat cataggctgt
    30241 gatcaatttt gtcccaacac cccatacatc aattttagct ttttgcatct ttaaattcaa
    30301 aatcgttgct tcatccaagt cattcgaagc atagattttt gcttccgtaa atccggctgc
    30361 atctaattgt tcccgaacac gcttagatat ataggccata tctccactgt cgatgcgtac
    30421 gccttggaag ttgattttgt cacctaattc tttcgccacg cgaatcgcac ttggcacacc
    30481 tgatttcaac gtatcataag tgtcgactaa gaacacgcag tctttatggg ttttagcgta
    30541 ggccataaat gcttcataat catttccata agattggact aacgaatgag catgggtccc
    30601 gctagctggt atcccaaata tcttcccagc acgtacattg cttgttgcat ctgctccgcc
    30661 gatatatgcc gctctagttc cccagactgc tgcatccagt tcttgtgccc gtctagttcc
    30721 aaattccaat agtggatctt ctccgatgac agatttgata cgagctgctt ttgtcgcgat
    30781 caacgtttgg aaattgacca tattcaacag tgctgtttct actaattggc agtgcgctaa
    30841 aggcccttcc acttggatta atggttcatt tgcaaaaact agttctcctt cacgagcaga
    30901 acgaactgtt gctttaaatt caaaattttg taaatactcc aaaaaacctt caggatagac
    30961 ttctaatcca cgcaagtaag caatatcgga atcattgaac gtcagattct ctaaataatt
    31021 gactaaccgt tccaatcctg caaaaaccgc gtatccgtgg ttaaaaggca tttctcgaaa
    31081 gtaacattca aaaacagcat gtaaatcagc tcgacctaat tcccagtatg tctgcatcat
    31141 attgatttga tatagatccg tatgcagcgt caaactgtcg tctgggtaag tattattcat
    31201 cttgtattac tcctcttggc aagttttcat ttcctaccca ttataacaaa aaaaattaat
    31261 aggaaaagaa atcttccatt ttttctgaaa aagcacatgt tttacggata tttcttgcta
    31321 aaaatgaact ccatctgcta aaactatcct ttcttattgg tatttaacct aaacgagaaa
    31381 gaatacttat tttattcaat gtatccgaga cacgaagaaa ttagcgtttt ctatttttct
    31441 tacttgataa aataagtaga ttttcctact acaatcgtag ccgttaagat accgatgatt
    31501 gaacaaatat aaccaaatgt ctctacaaca taatcaatgg caaaagtttt tgaagcaata
    31561 atacgtcttt ccttttttgc ttcttatccc caaagaaacg gatataactt attatgtatt
    31621 gaattttttt ggaaaggcga attatgacaa gatatacctt gcgttgaaaa aactcgcgga
    31681 aaaaatatca cacgttttta aaaagataca aagtaagaaa gcagctgtca atagaatgga
    31741 aacaaaaatg gcgagacatc aatcagtctc gccttgtttt ttattgtata cattagatat
    31801 ggagcaggtt accataaaga tgattattag tcgttattaa atagaatcct tcgtattttt
    31861 ttgttctatc actacaatat ctttatttgg acgtttgaat tgtattccgg cacgttctag
    31921 ctcctgtttc actcctacat ggactttgac atcttctcgt gtcattttta aaacgtgatg
    31981 aatcgcatag tcgatttctt gccttgtgat ttttttcttc gtattgatca tcacgacttg
    32041 ctttttatca tatgtgtcta ccaatagcag ttgtgttcga tctaacgaaa ataatttgta
    32101 ataattaata gccgtattcc caaaaaagaa ttccactact ttaggataaa atgtcttaat
    32161 atttaaatta ctattcacag gtgtttcgat tagcttcatc tcattcctct tttctatata
    32221 gtcgatttag atccaatctt aagttatgtt accatctttc ctagcattaa ggaatcggtt
    32281 acaattgaac ctttaaagac aaaaggattt accttttatc acttaatagt ataacataat
    32341 ttcgtgagaa aaaaatacaa ttttttcttg accatctcgt tacgtaaagg attatgctta
    32401 catttgtcag gaggaaaaat aatggagtac acaataaaga aaatgtcaga gatatcagga
    32461 gtcagtccga gaaccttgcg cttttatgat gagattggac tgctaaaacc agctaggatc
    32521 aattcttcag gttatcggat ttatggcaaa aaagaagtcg atcgtctgca acacatctta
    32581 ttttatcgaa caatggcatt caagttggat gatatccaag aggtcttaga caatccatct
    32641 tttgaccacc agaaagcttt aatcaagcat cagcaaatgt tgctggaaaa acgggcacaa
    32701 atcgataccc tcttgacaac tgtccaacag acacttgata tgtacgaagg aggaagaaaa
    32761 atgagtgaca aagaaaaatt tgaagggttt aaacaacaaa agttgaaaga aaatgaagaa
    32821 tcctatggac aagagattcg acaaaaatac ggaaaaaaaa aggttacagc atccaatgaa
    32881 aaatggatga atatggataa agaaacgtat gaagaaatgc aaactgttga aaagcagatg
    32941 ttatttgatc tcactcttta cttaaaagaa ccagaagatg aaagcttagc agaccgtatc
    33001 ttccaagctc ataagaagtg gttctcttac agctggcctg aatatcagcc aaaagcgcat
    33061 aaaggactag gaatgatgta cgaagccgat gaacggttca ctgcatatta tgacgagcga
    33121 agtggtcatg gtgcagcaaa agctttaaat gaaattatcc aaaaaaaggc gtaatctttt
    33181 acatgatcca acaaaaaagt acacgtaaaa tgacctaata acaaaacagc agacacccaa
    33241 gttagatttt tatgctaact tttggtgtct gctccattct ttcacaagtt ttttcatcct
    33301 actttaaata tattcatcgt tgaataaacg tataaggtat tttcacttta tccttttttt
    33361 ctgtaagaaa caattgaaat gccatttctc cgcaagcttc cagatggtgg tcgatggttg
    33421 ggaaaccaag aagctcgctg atcagcaaat tatcgcgtcc aatcaccact ggtgtcttat
    33481 cttgcagata gctttgcaag atgcctgctg caaccatatc cgaatttgta aagacaccat
    33541 caactccaag ctctttaaaa aagaagcctg cttgttttcc tttctctgca tctatacaat
    33601 cccaaaaaac aagtgattca tcaaaagatg gaaaaagttg atgacatagc tgcaaagtga
    33661 tttttgagtt ataacttagc ctgccacttc gccccaacgt gatgcccaat tgctttatac
    33721 cttgctgctt caaataagta agaccttctg taattgattg ttctcgatca ataaagacac
    33781 agcttgcctg ttttcccttg atttcttcac aaaaaactag aggtccatat ttttgatatg
    33841 ccaataaatc atctagtgta ttggcacgag acgtaatgat caatccatcg aaagctttag
    33901 ctgcaaattc ttcaagatac cttcgctctt tttctttatg atagcccgtc ggtaaaagtg
    33961 tcactttgta atcataatca aacgctgctt caatgatccc actgatcaac tgatcaaaat
    34021 acggatgatt ggtataaggc agaatcactc caatgctttt cgtttttcca taacttaact
    34081 gtctggcatt tgcattaggg atataatcga cttctttcat gaccgcaagt atttctttcc
    34141 ttttttcctc atctacatat ggatgtccat tgattacacg tgaaatagta gaaactgaat
    34201 aacctgtgag ctttgcgata tctcgaatgt ttgccactgc tgcttcgcca cctatacaaa
    34261 aagattttct tgtaaatagt ctaccacagc tggaccgcat tcaaaaaact gatacatttt
    34321 tccttcatgc gaaaaactga tccgctgccc gccccaatat atatcttttg tcaaattttc
    34381 gatttcattc attggtattt cttttactat attcctattc aacccttgaa aactgtacaa
    34441 cgttaatacg gatcccttga actcgacaaa cgcataaaaa taattgttcg ttgtgccatc
    34501 tgttatctct acataagtat tcattgcaag ccctcctttt gatactttga gtatagtgta
    34561 tgaaacgcgt ctcatagcaa ggagtttgtt ttgccaaaga aaagttttat tcctctttca
    34621 ttattaccaa agtctcttat tttaaattga atacattata atgatactgt aaatatatct
    34681 ttattattag tgaat
//
LOCUS       DAYYEF010000027        34695 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000027 DAYYEF010000000
VERSION     DAYYEF010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.027"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            598..1287
                     /locus_tag="ACHA1B_001480"
     CDS             598..1287
                     /locus_tag="ACHA1B_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFM8702248.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="ACHA1B_001481"
     CDS             1274..2482
                     /locus_tag="ACHA1B_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="HFM8702249.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="ACHA1B_001482"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="ACHA1B_001482"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HFM8702250.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="ACHA1B_001483"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="ACHA1B_001483"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HFM8702251.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="ACHA1B_001484"
     CDS             complement(6585..7280)
                     /locus_tag="ACHA1B_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HFM8702252.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="ACHA1B_001485"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="ACHA1B_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HFM8702253.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="ACHA1B_001486"
     CDS             complement(8479..8670)
                     /locus_tag="ACHA1B_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HFM8702254.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="ACHA1B_001487"
     CDS             complement(8691..9581)
                     /locus_tag="ACHA1B_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HFM8702255.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="ACHA1B_001488"
     CDS             complement(9568..10335)
                     /locus_tag="ACHA1B_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFM8702256.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="ACHA1B_001489"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="ACHA1B_001489"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0031167 - rRNA methylation [Evidence IEA];
                     GO_process: GO:0046118 - 7-methylguanosine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HFM8702257.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="ACHA1B_001490"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="ACHA1B_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0002098 - tRNA wobble uridine modification
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HFM8702258.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="ACHA1B_001491"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="ACHA1B_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HFM8702259.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="ACHA1B_001492"
     CDS             14906..15289
                     /locus_tag="ACHA1B_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702260.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /gene="jag"
                     /locus_tag="ACHA1B_001493"
     CDS             complement(15457..16215)
                     /gene="jag"
                     /locus_tag="ACHA1B_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding cell elongation regulator Jag/EloR"
                     /protein_id="HFM8702261.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="ACHA1B_001494"
     CDS             complement(16233..17051)
                     /locus_tag="ACHA1B_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0032977 - membrane insertase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YidC/Oxa1 family membrane protein insertase"
                     /protein_id="HFM8702262.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="ACHA1B_001495"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="ACHA1B_001495"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004526 - ribonuclease P activity
                     [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFM8702263.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="ACHA1B_001496"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="ACHA1B_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000315 - organellar large ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HFM8702264.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18180..19514
                     /gene="dnaA"
                     /locus_tag="ACHA1B_001497"
     CDS             18180..19514
                     /gene="dnaA"
                     /locus_tag="ACHA1B_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003688 - DNA replication origin binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA];
                     GO_process: GO:0006275 - regulation of DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HFM8702265.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19712..20842
                     /gene="dnaN"
                     /locus_tag="ACHA1B_001498"
     CDS             19712..20842
                     /gene="dnaN"
                     /locus_tag="ACHA1B_001498"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009360 - DNA polymerase III complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HFM8702266.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21071..21313
                     /gene="yaaA"
                     /locus_tag="ACHA1B_001499"
     CDS             21071..21313
                     /gene="yaaA"
                     /locus_tag="ACHA1B_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HFM8702267.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21300..22424
                     /gene="recF"
                     /locus_tag="ACHA1B_001500"
     CDS             21300..22424
                     /gene="recF"
                     /locus_tag="ACHA1B_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HFM8702268.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22421..24367
                     /gene="gyrB"
                     /locus_tag="ACHA1B_001501"
     CDS             22421..24367
                     /gene="gyrB"
                     /locus_tag="ACHA1B_001501"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005694 - chromosome [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HFM8702269.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24387..26858
                     /gene="gyrA"
                     /locus_tag="ACHA1B_001502"
     CDS             24387..26858
                     /gene="gyrA"
                     /locus_tag="ACHA1B_001502"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_function: GO:0003918 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006259 - DNA metabolic process [Evidence
                     IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HFM8702270.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27094..27393
                     /gene="rpsF"
                     /locus_tag="ACHA1B_001503"
     CDS             27094..27393
                     /gene="rpsF"
                     /locus_tag="ACHA1B_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HFM8702271.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27443..27955
                     /gene="ssb"
                     /locus_tag="ACHA1B_001504"
     CDS             27443..27955
                     /gene="ssb"
                     /locus_tag="ACHA1B_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFM8702272.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27981..28217
                     /gene="rpsR"
                     /locus_tag="ACHA1B_001505"
     CDS             27981..28217
                     /gene="rpsR"
                     /locus_tag="ACHA1B_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HFM8702273.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28360..30333
                     /locus_tag="ACHA1B_001506"
     CDS             28360..30333
                     /locus_tag="ACHA1B_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HFM8702274.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30339..30791
                     /gene="rplI"
                     /locus_tag="ACHA1B_001507"
     CDS             30339..30791
                     /gene="rplI"
                     /locus_tag="ACHA1B_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HFM8702275.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31065..32432
                     /gene="dnaB"
                     /locus_tag="ACHA1B_001508"
     CDS             31065..32432
                     /gene="dnaB"
                     /locus_tag="ACHA1B_001508"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HFM8702276.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33212..34504
                     /locus_tag="ACHA1B_001509"
     CDS             33212..34504
                     /locus_tag="ACHA1B_001509"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004019 - adenylosuccinate synthase
                     activity [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0006164 - purine nucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HFM8702277.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT        10565 a         6739 c         6861 g        10530 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgcggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtgt attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggag tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaatgg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg tgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tatatttttt atccacagat gcaagaggaa atctattgat ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa cttttttttg acaactgtgt ttttctcttt tttctttttg
    18061 tcgattgtgt ggataattgt aattaaaaaa tttttttctt cggtttctgt ggaaaactat
    18121 tgaaaaaaat gctaaattag tactagttat tcacttttta atgaaggagg aggccttata
    18181 tggtatccct cgatgcttta tggaatgaat taaaagcaac ataccaaaag gatttatcgc
    18241 ctgctagcta taatacatgg atcgaaacag cgaaccctcg aacccttgat caaaaccagc
    18301 tcgttgttga ggttcctagc aagattcata aagaatattg ggaaaaaaac ctggcgacaa
    18361 aaatcgttga agtcggttat atgttatcag gaaatgagat tatccctcgc tttattactg
    18421 gcgaagaagc agagcaagaa gaagttatag aagaaaaaaa tccaaaagtt gtggcaccta
    18481 gtccgctaaa aaaagccatg ctgaacccta aatatacctt tgatacgttt gtcattggta
    18541 aaggaaacca gatggctcat gcagcagcgc tcgttgtagc agaagatcca ggttctattt
    18601 ataacccgct cttcttttat ggaggcgtgg gacttggtaa gactcacttg atgcatgcaa
    18661 ttggtcatca aatgctgcaa agtcagccta atgccaaagt aaaatatgta agcagtgaaa
    18721 cttttgctaa tgatttcatc aattcgatcc aaaacaaaac agcagaagag ttccgtcaag
    18781 aatatcgaaa tgttgattta ctgctagtgg atgacattca attttttgca gaaaaagaag
    18841 ctacgcaaga agagtttttc catactttca atgccttgta caatgaaggg aaacaaatcg
    18901 tactaaccag tgatcggttg ccaaacgaga ttccgaaact gcaagaacgc ctcgtttctc
    18961 gctttgcatg ggggctgtct gttgatatta caccgccgga tcttgaaaca agaacagcga
    19021 ttttacgtaa aaaagcggcg gctgaacgtc tagagatccc agatgacaca ctaagctaca
    19081 tcgcaggaca aattgattct aacattcgtg aattagaagg tgcgcttgtt cgagtgcaag
    19141 cttttgctgc gatgaatagt gaagatattt cgactagtct agctgcagac gcactgaaaa
    19201 cgttaaaatc aggaaaagga catcctcaat tgtcaatcct gcagatccaa gaagaagtgg
    19261 caaagtatta tcacatccaa ttgaaagata tcaaaggaaa gaaacgcgtc aaatctattg
    19321 ttgttcctag acaaatcgct atgtatttgg cacgtgagct cacagataat tctttaccga
    19381 aaatcggagc tgaattcggt ggcaaggatc atacaacggt tatccatgct catgaaaaaa
    19441 tccagcagct gatggattct agtgtcagta tgcaaaatga agtatcagaa atcaaaaact
    19501 ttttactaaa ttaatttgtc gattctatca actgaaaata gcatgtggat aaaagaaaaa
    19561 aacgttcaaa agttatgcac actttttcca cagctgtttt ttcgtttctc tcttacgttt
    19621 tttgagtttt ccacagaatc aacatgccct attactttta ttattctttt taactaataa
    19681 taaataaaca aacattcaaa ggagatacat catgaaagtt actttaaacc gagctagctt
    19741 tatgcaggaa ttgcaaactg ttcaacgagc tatttcaagc aaaaccacga tccctatttt
    19801 gacaggtgta aaaatcacac tgacacaaga aggtttgact ttgacgggga gcaacgctga
    19861 tatatcaatt gaaacttttt tgtctgttga aaacgaaaaa gcaaatatgc aaatcgaatc
    19921 tactggttcc attgttttac aagcacgttt ctttagcgaa atcattcgga gacttcctga
    19981 agaaacattt actttagaag ttttagaaaa taaacaagta gcgattactt ctggaaaagc
    20041 gaattttatc gtaaatggat tagatgcaga taactatcct catcttcctg ttgtcgaaag
    20101 ccataaccag atgaaattac ctgtacacgt attgactaaa ctaatcaacg aaacagtttt
    20161 tgctgtctca caacatgaga gtcgtccaat cttgacaggt gtgcatttca ttttatctga
    20221 taattcttta ttggctgtag ctactgattc tcaccgtcta agtcaacgcg tgattccagt
    20281 agaacaagcg gctgatcatt ttgatattgt tattcctgga aaaagtttga tcgaattatc
    20341 tcgctcatta acaaatgaag aagaaatcgt cgaaatcagc attatggaaa accaagtgtt
    20401 gttcaaaaca gaaacgatgt atttctattc ccgtttgcta gaaggaaact atcctgatac
    20461 caatcgtttg attccttcaa gttttaatac agaggttgaa ttttctgttc ctagcttttt
    20521 agcggcgatc gaacgggctt ctttactttc tcatgaaggc cgtaacaaca tcgttcgttt
    20581 atctattcgt ccagatgcgg ttgttttata cggaaattcg ccagaaatcg ggaaagtaga
    20641 agaaagcttg agttatacag caagcagtgg cgatccatta gatatttctt tcaatccgga
    20701 ttatatgaaa gcagcgttgc gtgcatttgg agatatgagc atcaaagtga aatttatctc
    20761 tgctattcgt ccatttacat tggaaccaac ggaagatggc gttcaattta ttcagctgat
    20821 tactcctgta cgtacaaatt aacaatgatt ttcattgttc ttgaaaattt aattgaaaag
    20881 aaatagaaaa aataaaattt taaacagaag gccctaaaat ctcttttaag gctttctgtt
    20941 tatttttgtt taaatcacct tttttagatt aaatcgtctt atatggaaaa atatatggat
    21001 aaatttgttt tattgcgaaa aaaaaggtat aatagagtat acttttaata atgaaaatga
    21061 gggatgggca ttgaaacaac aagtcattct aaatacggaa ttcatgacgt tgggccaaat
    21121 gttgaaagaa gtcacagtta tcggtagtgg cggacaagca aaatggtatt tggcagaaaa
    21181 cactgtgtta gtcgatggcg aaccagaaaa tcgtcgtgga cgcaaacttt atcccggcat
    21241 gatggttgaa gttccagaag taggaacttt ttttatggta aaaaaaggaa acgacgataa
    21301 tgaggctgaa taagctgtat ttaaaaaatt atcgaaatta cgaagagctg aacatcgaat
    21361 tttccaagaa cctcgtcatc tttttaggag aaaatgcgca aggaaaaacg aatcttttgg
    21421 aaagtatcta cgtattagct atgacgcgaa gtcatcggac aagtagtgag caggaattga
    21481 ttggctggac tgacgatcag gcgatgattc aaggagagat cacaaaaggt tcatccactc
    21541 ttccattaga aatcttatta tctaaaaaag gccgaaaaac caagatcaac catatcgaac
    21601 aaaaaaagtt aagtacttac gtgggacaaa tgaatgtcat tttatttgca ccagaagatc
    21661 tttctttagt aaaaggcagc ccgcagatca ggcggaagtt tttagatatg gaattaggcc
    21721 agatcaatcc aatctatctt tatgatcttg tccaatacca agcaattttg aaacaaagaa
    21781 accagtattt aaagcaattg aatgaaaaaa aacaaactga tttgctttat ttggatattt
    21841 tgtccgaaca actagcagcg tttggcagca aagtattgaa agcaagagca cagttcgtca
    21901 agcgattgga gttttgggct aattctttgc atcagcaaat cacccatcaa aaagagcagc
    21961 tggaaatcga gtatctcacc gcagtcgatt ctttagaaac acatacgcaa gagcaaatcc
    22021 aagaacaatt tctcgcactt ttgaaccaaa ataaaaagaa agaccttttt cggggaacaa
    22081 cgacagttgg tcctcatcgt gacgatcttt ccttttttat taatcagaaa aatgtgcaga
    22141 cttatggatc gcaaggacag caaagaacaa ctgcactaag tgtcaaatta gcagaaatcg
    22201 atttgattaa agaagagacg ggggaatatc caatcctttt gttagatgat gtgatgagcg
    22261 agctggatga tagtcgtcaa ctccatctgc tagaaacaat cgaaggaaaa gttcaaacgt
    22321 tcttaacaac aacgacactt gaccatgtaa aaaataaaat gactgttgaa cctgagattt
    22381 tttatgttca acaagggaaa ctaaaaggag aagaaactga atgacagaag aaagaagttt
    22441 agtagaacgc gctaaagagt atgatgccag tcagattcaa gtacttgaag gacttgaagc
    22501 cgttcgtaaa cgacctggca tgtatatcgg ttcgactagt tctgagggtc tgcatcacct
    22561 tgtttgggaa attgtcgata attcgatcga tgaagtatta gcaggttttg caacgaaaat
    22621 ccatgtgatt attgaaaaag acaacagtat caccgttatt gacgacggtc gggggatacc
    22681 tgtagatatc caggcaaaaa ctggacgtcc tgcagttgaa acggtcttta ctgttttaca
    22741 tgctggagga aaattcggcg gtggtgggta caaagtttct ggtggacttc acggagtagg
    22801 atcttctgtt gttaacgcgc tttctacaca gcttgatgtc aaagtataca aagaaggaaa
    22861 tgtgtactat caagaatatc gtcgtggagc tgtagtggac gacttaaaga ttatcgaaca
    22921 aacggatcgc catggaacaa cggttcactt tacgccagac cctgaaattt ttacagagac
    22981 aactgagttt gatttttcaa aattggctac ccggatccgt gaacttgctt tcttgaaccg
    23041 cgggatgcgt atatcgattg aagacaaacg agaagaagaa ccagtcatca atgaatacca
    23101 ttatgacggc gggattaaaa gttatgtcga atacttgaat gcaaacaaaa ccgtgatttt
    23161 tccagaacct gtatatttgg aaggtgaaca gcaagatatc gcagttgaag tctctatgca
    23221 atatacagac ggctaccatt ccaatatcat gagttttgcc aacaatatcc atacgtatga
    23281 aggcggaaca catgaatcag gattcaagac tgctttaact cgtgtgataa atgattatgc
    23341 ccgaaaacaa aagctgatga aagaaaatga cgacaacttg accggtgaag acgtgcgaga
    23401 aggattgaca gctgttattt ctatcaagca tcctgaccct caattcgaag gacaaacaaa
    23461 aacaaaattg ggcaattccg aagtacggac agtcactgat cggttattta gcgaacattt
    23521 catgaaattc ttgctggaaa acccaagtgt gggccgtcaa attgttgaaa aaggattact
    23581 agcttccaga gctcgtctag cagcgaaacg tgcgcgtgaa gtaacgagac gtaaaggtgc
    23641 tttagagatt agtaatctgc caggaaaatt agcggactgc tctagcaacg atcctgaaaa
    23701 atgcgaattg ttcatcgtcg aaggagattc ggccggcgga tcagctaagc aaggtcgtaa
    23761 tcgagagttt caagccatct tgcctattcg tgggaaaatc ttgaatgttg aaaaagcaag
    23821 catggacaag atcttggcaa atgaagagat ccggtcttta tttactgcta tgggtacagg
    23881 gtttggagaa gattttgatg tatcgaaagc tcgctaccac aaattagtta tcatgactga
    23941 tgccgatgtc gacggcgcgc atatccgtac attgctgctg actctttttt atcgttacat
    24001 gcgtcctatt gttgaagctg gatacgtcta tattgctcag ccacctttat acggggtaaa
    24061 acaagggaag aatattacgt atgtacaacc aggaaaaaat gcagaagaag agttgaaaca
    24121 agtcgttgct tcacttcctg cctcaccaaa accaagcgtt cagcgttata aaggacttgg
    24181 agaaatggat gatcatcaac tatgggaaac aactatggac ccaagcaatc ggatgatggc
    24241 ccgcgtcagt gtggacgatg ctattgcagc agatcagata tttgaaatgt tgatggggga
    24301 tcgagtagaa ccccgtcgtg cattcatcga ggaaaatgca cactatgtga agaacttaga
    24361 tatttaatca tgaaggagga aaaagaatga gtgaagaaat cagagaaaac atccatgatg
    24421 tcaatctaac cagcgaaatg aaagactcct tcatcgatta tgcgatgagt gttattgtcg
    24481 cacgtgcact tcctgatgtc agagatggtc tgaaacccgt tcatcgccgt attttatacg
    24541 gcatgaacga attaggtgta acaccggata aagcccataa aaaatctgcc agaatcgtcg
    24601 gagatgtcat gggtaaatac catcctcatg gagactatgc gatctatgag tcaatggtac
    24661 ggatggcaca gccattcagc taccgttata tgctagtgga tggtcatgga aactttggtt
    24721 ctgttgacgg tgacggtgcc gccgctatgc gttataccga agcacggatg agcaaaatcg
    24781 ctacagaaat gctgcgtgat atcaataaga acactgttga tttccaaagc aactatgatg
    24841 atacagaaaa agaaccagtt gtactacctg ctcgcttccc gaatctttta gtgaacggaa
    24901 caacggggat cgccgtaggt atggccacga atatcccacc tcataacttg tctgaggtag
    24961 tagcggctat cgatttgctg atggataatc ctgatgtgac gaccaatgaa ttgatggaag
    25021 tattacctgg accagatttt ccaacaggtg gtttggttat gggaaaatca ggaatccgaa
    25081 gagcgtatga aacaggtaag ggttctatta ccgtacgtgc aaaagttgag attactgaga
    25141 tgccaaatgg taaagaacgg atcatcgtga cagaattgcc ttatatggtc aataaagcaa
    25201 aattgatcga acggatttct gaactgcaca gagacaagcg tatcgaaggg atcacagatt
    25261 tgcgggacga atcttcccgt gaaggtatgc ggatcgtcat tgacatccgt cgtgacgcca
    25321 gcgcatctgt tatcttgaat aacttatata aattgacatc cttgcaaaat tcatttggat
    25381 tcaatatgtt ggcgatcgaa aaaggtgtgc cgaaagtttt gagcttgaaa caaattcttg
    25441 aaaactatat cgaacatcag cgcgaagtca tcacaagacg gacagtcttt gaaaaagaaa
    25501 aagcagaagc aagggcacac attttagaag gtttgcgtat tgctttggat catatcgatg
    25561 aaatcattgc gattatccgc gggtctaaat cagatgacga agcaaaagcg acgatgatcg
    25621 aacggttcga tttatccgat cgccagtctc aagctatttt agatatgcgt ttacgccgat
    25681 tgaccggttt ggaacgggaa aaaatcgaaa atgaatacca agaactctta aaactgattg
    25741 aagatttaac tgacattctg gcaagaccag aacgtgttac agaaatcatc aagaatgaat
    25801 tagcagactt gaatcaacga tttggtgata aacgacgcac agaattacta gtcggtgagg
    25861 tcttaagtct ggaagatgaa gatttaatcg aagaagaaga aatcgttatt acattgacaa
    25921 acaatggtta catcaaacgt ttggcaaata atgaattcag agctcaacga aggggtggac
    25981 gtggtgtcca aggaatgggt atccacaatg acgacttcgt caaaaatctg gtttcttgtt
    26041 ctacccatga tacattgtta ttctttacga ataacggaaa agtgtatcgg gcaaaaggat
    26101 acgaaattcc agaatacggg cgcacagcca aaggaatacc aattatcaat ttactaggta
    26161 tcgattcgag tgaaagcatc caggcaatca ttgcggtgac gggagaagca gaagaaggcc
    26221 actatctctt ctttacgacg cgtcaaggta cagtaaaacg tacttctgtc actgcttttg
    26281 ctaacatccg aagtaatggt ctgatcgcaa ttggtttgaa agaagacgat gagctcgtca
    26341 atgtgctact gacagatggt caatctaata tcattattgg aacacataac ggctactctg
    26401 tcactttcaa agaagaagca gtccgcgata tgggacgtac agcttccggg gttagaggaa
    26461 tacgcctgcg tgaggaagat tatgtcgttg gggcagcctt aatgaaggaa gatcaagaag
    26521 tattagtgat cacagaaaaa ggttacggaa aacggacaaa agtatcggaa tatccagtga
    26581 aaggccgcgg aggtaaaggg atcaaaacgg cgaacatcac tgaaaaaaat ggtccactag
    26641 ctggattgac cactgtttct ggagatgaag acatcatgct gattacagat aaaggtgtca
    26701 ttatccgttt caacgtatcg actgtttctc aaactggacg ttcaacatta ggcgtacgtt
    26761 tgatgaagat ggaagctgat acgaaagttg tcacgatggc agcagtcgaa ccagaagctg
    26821 cagaacaaac agttgaagaa caaggatcag aagaatagcc atcaagacta attgtgtaag
    26881 ctagcaagaa tgaccgatta aaaaatctgg ttattcctgc tggctttttt gattagttga
    26941 atttctctta aaatattcga aactgttcat tctgtattgc ttttgaccaa aatagagtgt
    27001 ataatcagag cttgtgagta gtctaattaa ttagataact ctccttgctc ttaggaacct
    27061 aagagccgaa agtccacagg gaggtgaata tcaatggaaa acacgaaata tgaaatcatg
    27121 tacattattc gtccaaacat tgatgaagaa gcaaaaactg ctttaatcga acgtttcgat
    27181 gcaatcttga aagataacgg agcagaagtt atcgaatcaa aagattggga aaaacgccgt
    27241 ttcgcttatg aaatgaacgg ttaccgtgaa ggtatctatc acatcgttaa agtatcttct
    27301 ccatcatcag caaatgctgt caatgaattt gaccgtcttg ctaaaatcaa cgacgatatc
    27361 attcgtcaca tgattgttaa agaagaagct taattgttgt ttcatgtgaa acaatagaaa
    27421 acgatgagag gagatgacta ttttgattaa taatgttgta ttagttggac gtctgacgaa
    27481 agatccagat ttgcgttaca cagcaagtgg tacggcagtc gcaacattta ctttggctgt
    27541 gaatcgtaat tttacaaacc aaagcggcaa tcgcgaggct gattttatca actgtgtgat
    27601 ttggcgcaaa tcagcagaaa ctttagcaaa ctatgctcgt aaaggaacac ttttaggtgt
    27661 tactggacgt atccaaactc gttcttatga taatcagcaa ggacaacgtg tatacgtgac
    27721 agaagtagta gctgacaact tccaattgct ggaaagtcgt tctgcatctg aaaatcgcca
    27781 acaaagcggc ggattccaaa gttctggtca atcagctggc ggatttggcg gaaacaataa
    27841 ctctaatcaa acatctcaat catccaacgg tatgcctgat ttcgaccgtg atacttctga
    27901 cccattcggc tcaagttcaa cgatcgacat ttcagacgat gatttaccat tctaaacgaa
    27961 tttgatagga gggaaataga atggcacaac aaagaagagg cggacgtaaa cgtcgtaaag
    28021 tagactacat tgctgctaac catattgaat atatcgatta taaagatatc gaattactaa
    28081 aaagatttat ttcagaacgc ggtaaaatct tgccacgtcg tgtaactggt acaggcgcta
    28141 aaaaccaacg taaaattact gttgcaatca aacgcgctcg tatcatgggc ttgctacctt
    28201 tcgttagcga agactaataa atcctaggaa ttgaatgact gatccttttg atcagctatt
    28261 caattccttt ttttctgtaa aaataacctc tattcgttta gtcgctcgaa tgacgaaagt
    28321 tatggtaaaa tcaaattagt catatatggg aggaaaatta tggaaaataa aaacaatcat
    28381 ttatccccga aacctctctt ccttatcctg tttatattaa tcgaagtatt ggtagtctta
    28441 attttaccat ttcgttttgt tagcgcttcg gtcattctat tgatgaattt atggggtgtt
    28501 cgctattggt tgaaaatgaa acgttggctt attttaaata aacgtgaaaa aatccagcag
    28561 gcttcgactg tagctgaaac caatctagct tatgtctcag aagtcatgcc tgtaggagtg
    28621 attgcttatc agccatcaag ccaaaaaatc gaatggctca atccattagc attgaaaatc
    28681 aaagatcaaa gtggattaac agaggaagaa ttgctagata ctttttttac tgcaaaagaa
    28741 aaaaagaaaa accaagtcta tctagcagat aaaacatttc agtttgatat ggatacagta
    28801 aagggtgttg tttattttaa tgatattacc caaaaccagt tgttaaaact ccatcagacg
    28861 aacagtcagc cggtgattgg tattttatct attgataact atgcagatgc cattgataaa
    28921 ttggatgaca aagagatttc ttatttgaac tctttcgtca ctacactagt ttctgactgg
    28981 atgaatgaat accatgtctt tttcaaaaga atcaacgcag aacggttttt cttcgtagca
    29041 cagatgatcg atctgaaaaa gatgatggat aaaaaatttg atttgctgga tcgctttcga
    29101 gcagaagctg aaaaacagag ctcgcctatc acccttagta tggggattgc ttatggctca
    29161 agaaccctcg atgaaatcgg tggagaagct cagaataatt tagatgttgc tttagtccgt
    29221 ggaggcgacc aagttgtcgt gaaagaggta aaagaaggag caaaacctgt ttattatggg
    29281 gggaaatctg ctaagaatgt caaacgcacg cgtgttcgtt ctcgagcgat gagtaccgct
    29341 ttgcgtcgga tttttgatga aacaggcgat gtgtttatca tggggcacaa gtttccggat
    29401 atggatgctt taggctctgc ttttggtgtc agttgtctgg cacgcttcaa ccagaaaaaa
    29461 gcttacatcg ttatcaacga gaacgagatc attccagatg tagaacggtg tcttgaagaa
    29521 atccataagc atcctgaatt agaaatgcaa ctaatctctc cagaacgtgc catagagctg
    29581 aaaaaagaag aggacctcct cgtgatggtg gattaccata aaccttctct atcgatctct
    29641 cagggcctat atgagcaatt tgataagatt gtgatcattg atcaccatcg tcgtggggaa
    29701 gagtttccaa gtaaacctct gctgacttat atcgaatctt cagcttcttc agcttcagag
    29761 ctagtttctg agctgatcca ataccaaagc agcaaaacaa atcgcttaga tcgttttgag
    29821 gccacattat tgcttgcagg gatggttgta gatacaaata gtttcaatgt ccgtacaact
    29881 gcacgaactt ttgacgttgc cagctattta aggtcttgtg gagcagacgc atccttagta
    29941 caatatttat tgagctcgga tttagcgaca tacttggaga tcagcaattt gattgctgga
    30001 agcgactatg tgacttctga tattgttgtg gcggcaggga cagacgaaaa agagtataat
    30061 agtgttatag cagcaaaaac agcagataca ttgctttcga tgatcaatat caatgcagct
    30121 ttcgtcatta caaagcggac agacggcttg attgggatca gtgccagaag taccggcacg
    30181 atcaacgtcc aaatcatcat ggaatcctta ggtggcggag gacacttcac aaacgcagct
    30241 actcaactgg aaaatacgac agttgaggaa acaaaacaga agctatttgc tgcaatcaaa
    30301 gaaaatatga atcaaatata tgataaggag taatccaaat gaaagtaatt tttttacaag
    30361 atgtaaaagg aaaaggtaaa aaaggggaca tcaaagaagt tccagcaggt tatgcacaaa
    30421 attatctaat caaaaataac ttggcaaaag aagcaacgaa aagcagtatc agtcagttag
    30481 caggacaaaa gaaagcacaa gaaaaacacg aagctgaaat cttggaagaa gctaaaaagt
    30541 taaaagaatt cttggaaaaa gaagatactg tagtcgaatt gaaggcgaaa gcaggggaag
    30601 acagccgttt gtttggttcg atcccttcaa aacaaattgc tgaagggtta aacaaacaat
    30661 acaaaatcaa attagataaa cgaaaaatcg aattagaaaa tccgatccgt tcactaggct
    30721 acacaaacgt acctgttaag cttcatcatg aggtgacggc tacgatcaaa gttcatgtcg
    30781 tacaagaata acaaatcttg atagcgatgt tcagctggta agtataacca gaaggaaaaa
    30841 agacaaaccg aaatttatct gagaaaacag ctgcagcaat gaaagcaaaa gctgcaaatc
    30901 gatttcagat tgatttcggt ttcttttttg ggaacagcaa aatagcataa agaaaacgag
    30961 tataataaaa gagaactatt tttttattac actttcggta cgaatgatga cttttctctc
    31021 attttcttgt aaaatgaagc aattgaagac aaggagcgat acgtatgaat gaagtgtggc
    31081 aggatcgaat cccaccgcaa aatattgaag ctgaacaagc ggttttaggc tctgtttttc
    31141 ttgacgcaga aacgatcatt gatgccatgg agtacataga gccaaaagac ttttatcgtc
    31201 gtggccatca aattattttt gagacaatga tcgagttaaa tgatcgtaat gaagcgattg
    31261 acgtggttac tgtcaaagac cggctggaac aagccaattt gttagaagat gccggtggtt
    31321 taagttatct ctcagacttg gcattagcag ttccgacagc agcaaatatc gtctactatg
    31381 cgaaaatcgt tgaagaaaaa tcattgctgc gtacattgat ccagacagca acaggaatcg
    31441 ttacgaaagg attcgagcaa ggagaagaag ttcaaacaat tttagatgat gccgaacgca
    31501 gtatcttgga ggtttcggaa aaaagaaatc gaagcggctt tttatctatt gctgaagtac
    31561 tgaactccac gattgaaaat atcgatcgac tagctcaaaa caatgaagaa atcacaggtc
    31621 taccaactgg ctatcaaggt ctggataaaa tgacagcagg tttccagccc gaagaactaa
    31681 tcattcttgc tgcacgtcca gcggtaggta aaacagcgtt tgcattgaat attgctcaaa
    31741 atgtaggaac aaaaacagat cgttctgttg cgatatttag tttggaaatg ggggcagaat
    31801 ctcttgtaaa tcggatgctt tgtgcagaag gttcgattga ggccagccat ttacgtacag
    31861 gtcagctttc ggaagaagaa tggtcgaatc tgatcgttgc gatggggagt ctttctcgag
    31921 caaatatttt tatcgatgat acaccaggga tcaaaatctc tgaaatccgt gcgaaatgtc
    31981 ggaaactagc gcaagaaaaa ggcaatctag gcttgatatt gatcgattat ttgcagttga
    32041 ttgaaggtaa cggtaaagag aaccgtcaac aagaagtatc agatatctct cgccaactga
    32101 aaaaactggc gaaagagctg aaagtacctg tcattgctct ttcacagtta tctcgtggag
    32161 tagaacagcg acaagacaaa cgaccagtgc taagtgatat tcgtgaatcc ggatcaattg
    32221 aacaagatgc ggacatcgta gccttcttgt atcgagatga ttattatgaa agagaaggcg
    32281 gagatgacga tgatggaaac gagccaaaaa atgacaacgt catcgaagtc atcatcgaga
    32341 agaaccgaag cggtgcacga ggaacagttg aactactgtt tatcaaagaa tacaataagt
    32401 tttcgtcgct ttcgccaaga gaagaatttt aaagaagagg ttgtgagcct tgagcaatcc
    32461 cgagagctct cgtaagaaga tgcaaggagt aaccgcagga acgactagag tacttaattt
    32521 aaacagatct ccaaagggat tgtgacaaaa gtcttgtcac agtccctttt tccgaataaa
    32581 cggtgttcaa tcagctgacc cttggtatta gctcagcaaa cgtcaaaata tgaggaacta
    32641 ttttgacgtt tgtttctcta atactcaggt caaaacgctg atcttacgac ctcttttcct
    32701 taaacggtgt tctcctgcca actcctcggt cacaagtcac aatatcatca aacatgagaa
    32761 gcagtttttt gaaattgctc cttgtgactc agagttaaac ggcaggctca caacctcttt
    32821 cttaaacggt gttcaaaagc ttgcatctgc ggtaatacgc ccaatcaaac gaaaaatatg
    32881 agaagctatt tttgtttggc tgttcttatt acttgatgca ggacagcttt ttcacaacct
    32941 ctgattcacg gtgttccaaa agtagcttct tcgaaaaata agtcgaaatt tcacaaaaat
    33001 ttgagaagca attttcgtac attccttctt atttcttgaa gctgaccact tctgttacaa
    33061 cctctttttt aataaccatt ctaaaaagat aaagttcgtt ttttaagcgt ttttataaaa
    33121 taaaaataaa aatcattcga ttttatttga aatatgtatc tattattgat acaatggttc
    33181 aggattaaat aatatagaac gaggtgttca catgtcatct gtagtagtag taggtacgca
    33241 atggggcgat gaagggaaag gaaaaatcac agactttctc agtgaaaatg ctgaagtgat
    33301 tgcacggtac caaggtggcg acaatgcagg gcacacaatt aagtttaacg gtgtgactta
    33361 taaactgcat ttgattcctt ctgggatttt ttataaagac aagatcagtg tgatcggaaa
    33421 cggcgttgta gtcaatccta aatcattggt taaagaatta gcttatttac atgaaaaagg
    33481 tgtagaaaca agtaatttgc gtatttctga ccgcgcgcac gtaatcttgc cttatcatat
    33541 caaattggac caattacaag aagatgctaa gggcgaaaat aagattggta caacgattaa
    33601 aggaatcgga cctgcctata tggataaagc agctcgtgta ggtatccgta ttgcagactt
    33661 attagataaa gaaatttttg aagaacgtct tcgtttgaat ctagatgaca aaaaccgtca
    33721 atttgtaaaa atgtttgatt cagaaccact tgattttgac gatatttttg aagaatatta
    33781 tgaatacgga caacaaatca aacaatacgt cacagatact tccgttatct tgaatgatgc
    33841 tttggatgca ggcaaacgcg tgttgtttga aggcgcacaa ggtgtaatgc tggatatcga
    33901 ccagggaact tatccttttg ttacttcttc taacccagta gccggtgggg taacaatcgg
    33961 aagcggtgta gggccttcaa aaatcaataa agttgtcggc gtctgcaaag cctatacgtc
    34021 acgtgtcggt gatggaccat ttccaactga attatttgat gaaacaggag aacaaatccg
    34081 cgaagtagga cgagaatacg gtacgacaac tggtcgtccg cgtcgtgtag gctggtttga
    34141 ttctgtagtt atgcgccatt ctaaacgagt ttcaggtatt accaacctat ctttaaactc
    34201 gatcgatgta ttaagtggat tggaaacagt aaaaatttgt acggcttatg aattagatgg
    34261 cgaactaatc taccactatc cagcaagctt gaaagagttg aaccgctgca aaccaatcta
    34321 tgaagaattg ccaggctggt cagaagacat tacaggatgc aaaacacttg cagaactgcc
    34381 agaaaacgca cgtaactatg tacgtcgtat ctcagagctt gttggtgtac gtatctcaac
    34441 attttctgtc ggacctgata gaacacaaac aaacatctta gaaagcgtct gggcgcaaat
    34501 ctaaggataa aaacgacgac tgaatcagga cgttcttacc agagcgagtc gaagtgttta
    34561 tctatacgat aataataact tgaagaggta gtgaaagaga cgtttagcct tattgccgat
    34621 aggctgtctc ttgaacactg tttattcaga ataagggact gtgacaaaaa ccgtgtcaca
    34681 gtcccttttt ccgaa
//
LOCUS       DAYYEF010000028        34118 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000028 DAYYEF010000000
VERSION     DAYYEF010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.028"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(98..1228)
                     /locus_tag="ACHA1B_001510"
     CDS             complement(98..1228)
                     /locus_tag="ACHA1B_001510"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003871 -
                     5-methyltetrahydropteroyltriglutamate-homocysteine
                     S-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HFM8702278.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1288..1515)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1877..3079)
                     /locus_tag="ACHA1B_001511"
     CDS             complement(1877..3079)
                     /locus_tag="ACHA1B_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8702279.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3139..3342)
                     /locus_tag="ACHA1B_001512"
     CDS             complement(3139..3342)
                     /locus_tag="ACHA1B_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFM8702280.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3484..4548)
                     /locus_tag="ACHA1B_001513"
     CDS             complement(3484..4548)
                     /locus_tag="ACHA1B_001513"
                     /inference="COORDINATES: protein motif:HMM:NF014537.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFM8702281.1"
                     /translation="MDSLQEEVVPVNRVLIDYLTIHFFSNQHLKLIEEIIEMPIERFE
                     ELDYAPKGYIGQYVWNQVITIRYSIDDAVKGTVMEFSGQGCKHLARWLKTRKTNWQQF
                     FRKVLDYQGNFTRIDFTLDDFVGSLSIPELKHKVILGHVWTTFQVSESHGGTDIINNE
                     SNGETLYLGSKKSQCRFCFYQKDHEQRKRRGIPLEEAKVKNRFELRYRKEKAQSLAKI
                     ISKTHDLTKLFFELLNGAICFYDRDPNDLGAKVDAKWAAFISNYGAITISLDTIPQSF
                     EKTMSWLIHGVSPSLVFIAQVDQTFHSSLLPLIIEQGEMNPRQIKLLQNMKADPEYYQ
                     EEVEYYERKLQSISNEKTSY"
     gene            complement(4609..4716)
                     /locus_tag="ACHA1B_001514"
     CDS             complement(4609..4716)
                     /locus_tag="ACHA1B_001514"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702282.1"
                     /translation="MNQVNQHDLGEAIRVSREERGWTQRYLAEKVGISR"
     gene            4879..5691
                     /locus_tag="ACHA1B_001515"
     CDS             4879..5691
                     /locus_tag="ACHA1B_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702283.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6066..6257)
                     /locus_tag="ACHA1B_001516"
     CDS             complement(6066..6257)
                     /locus_tag="ACHA1B_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702284.1"
                     /translation="MKQKFFIAIIATKKFHRGKRFGQKWKFPPKVTAPQLKSIKELEF
                     ENALVICMTCTDEVFRKHF"
     gene            complement(6502..6732)
                     /locus_tag="ACHA1B_001517"
     CDS             complement(6502..6732)
                     /locus_tag="ACHA1B_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702285.1"
                     /translation="MNFFGDRFFQPYKINRNSIIESCDYKKIARKKKKVSIHFKYFIP
                     ISIAKKVEILYLPLTLASLANVVSILIDNKLR"
     gene            complement(6716..6913)
                     /locus_tag="ACHA1B_001518"
     CDS             complement(6716..6913)
                     /locus_tag="ACHA1B_001518"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HFM8702286.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="ACHA1B_001519"
     CDS             complement(7059..7937)
                     /locus_tag="ACHA1B_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFM8702287.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="ACHA1B_001520"
     CDS             complement(7976..9094)
                     /locus_tag="ACHA1B_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 172 protein"
                     /protein_id="HFM8702288.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="ACHA1B_001521"
     CDS             complement(9091..11190)
                     /locus_tag="ACHA1B_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HFM8702289.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="ACHA1B_001522"
     CDS             complement(11241..12062)
                     /locus_tag="ACHA1B_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFM8702290.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="ACHA1B_001523"
     CDS             complement(12059..12868)
                     /locus_tag="ACHA1B_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFM8702291.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="ACHA1B_001524"
     CDS             complement(12889..13383)
                     /locus_tag="ACHA1B_001524"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM8702292.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13895)
                     /locus_tag="ACHA1B_001525"
     CDS             complement(13395..13895)
                     /locus_tag="ACHA1B_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM8702293.1"
                     /translation="MIKPMFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLS
                     SIQLLTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITK
                     TFLEKEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVN
                     EEEDFF"
     gene            complement(13960..16656)
                     /locus_tag="ACHA1B_001526"
     CDS             complement(13960..16656)
                     /locus_tag="ACHA1B_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFM8702294.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="ACHA1B_001527"
     CDS             complement(17084..18157)
                     /locus_tag="ACHA1B_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8702295.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="ACHA1B_001528"
     CDS             complement(18154..18981)
                     /locus_tag="ACHA1B_001528"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702296.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="ACHA1B_001529"
     CDS             complement(18982..19788)
                     /locus_tag="ACHA1B_001529"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702297.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="ACHA1B_001530"
     CDS             complement(19800..20885)
                     /locus_tag="ACHA1B_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702298.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="ACHA1B_001531"
     CDS             complement(20902..21444)
                     /locus_tag="ACHA1B_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HFM8702299.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="ACHA1B_001532"
     CDS             21702..22691
                     /locus_tag="ACHA1B_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HFM8702300.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="ACHA1B_001533"
     CDS             22688..23425
                     /locus_tag="ACHA1B_001533"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HFM8702301.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="ACHA1B_001534"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="ACHA1B_001534"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004633 - phosphopantothenoylcysteine
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HFM8702302.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="ACHA1B_001535"
     CDS             23989..24621
                     /locus_tag="ACHA1B_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFM8702303.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="ACHA1B_001536"
     CDS             24706..25353
                     /locus_tag="ACHA1B_001536"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding oxidoreductase"
                     /protein_id="HFM8702304.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="ACHA1B_001537"
     CDS             25358..26341
                     /locus_tag="ACHA1B_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HFM8702305.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="ACHA1B_001538"
     CDS             complement(26744..28258)
                     /locus_tag="ACHA1B_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HFM8702306.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="ACHA1B_001539"
     CDS             28396..29202
                     /locus_tag="ACHA1B_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702307.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="ACHA1B_001540"
     CDS             complement(29377..29946)
                     /locus_tag="ACHA1B_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8702308.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="ACHA1B_001541"
     CDS             complement(30029..32089)
                     /locus_tag="ACHA1B_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HFM8702309.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="ACHA1B_001542"
     CDS             complement(32366..33844)
                     /locus_tag="ACHA1B_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702310.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT        10254 a         7082 c         5748 g        11034 t
ORIGIN      
        1 aataaataat ataaaaggta aataaaaaag agtggatttc tccactccat gaaaagccga
       61 ctttttggga cgcttttttt tgccaagcct cacattttta tagccaaact tcttttgcga
      121 cttgctgcaa taattggatt ttcttccatt gttcttcttc tgttaaatgg tttccttctt
      181 ctgttgaagc aaacccacat tgaggactga tacttagatt ttccaatggt acaaattgtt
      241 gtgcttcttt tattcgttct tttattttct ccgtatcttc caaatctgga aacttagaag
      301 taactaatcc taaaacaact ttactttctt tgttactcca atgtcttaaa ggagtaaaat
      361 ctcctgctcg gtcagaatcg tattccaaaa agaaaccatc ataatttgtt gaaaacaact
      421 cttctgcaat gggttcatat ccaccggaaa acagccaaga agaagcgtga ttcccgcggc
      481 agatatgtgt tgtgatcgtc aaatcttctg gtttgtcttc cagtgcgtta ttgataatct
      541 ctgtacaaat atgggccatt tctttcggat caattccttt ttgaagaagt gcttctcttt
      601 tagtttgatc agctagaaac gcccaatttg tatcatcgaa ttgcaggtaa cggcaacctt
      661 tttcataaaa agcatgaatc gctgctttgt aagtagagga caagtcctca taaaaatcag
      721 atagatcagg ataaatctcc ttgatttttg aagaaccatc attagatagg atctcttgtc
      781 gtaaaatcat cgtgggacta gggatcgttg cttttgcaac aaaagtatca tctgtttcca
      841 ctacttcttt cagaaaagca aaatctttta aaaatgggtg atttggattg aaagataatt
      901 tatctactac ccgaatatta taagctggtg ctgcttttcc gtggaatgtt tgattatatc
      961 cagtttctgg aacatagcct tcgataccat ttagttcttc taaaaaatca agatgccaaa
     1021 atccacgccg aaattcacca tctgtaattc ctttgatgcc gactgctttt tggtcttcca
     1081 ctaatttttt tatttcctgg tcttcgattg cacgaagttc ttcttttgaa agtaagcctt
     1141 cttgaacttt ttttcttgct tctttgatcg attgcgggcg taagaaactt ccgacatgat
     1201 ctactgtaaa tggtctattt ttgctcattt cactcactct tttctttgtt ttttgtaaaa
     1261 aaaaatcctt ttactagcaa atactagtaa aaggacgatt atactcgtgg taccaccttt
     1321 tttcagaaaa aacattcttt ctctcagcct gacaataaaa tcagtggtct tggtaacgaa
     1381 agactgttcg tttttgccta cctttcgaca aaaaatcctc taaggccatt ttcgacagtc
     1441 aacttctagc tttttacacc aaccaaagcc tctcttgaac cattttctgt ctactttcct
     1501 tctcatcgga tactattaga ataaaattag aatagcatgt ttgaaagaaa agtcaatagg
     1561 gaataagaac aaacaaaaac taatttgtta ttcttagtaa tttgtttgtg gaatacaata
     1621 aagcttttct aatatgataa ttgttcagtc gtcctttcat cttagatcac ttccttaaaa
     1681 tgatcatacc cgtttcaacc acataaaaaa ggacttaatt ttgaaaaatt tcccatcaaa
     1741 actaagtcct ttttattata gttatgcaaa tttgcttatt ttctcgctat ttccgataca
     1801 tcttgaacag gagcaattcg actgaaaaca ctggtgcaaa agcatttatt tgtcttatgg
     1861 tagaaccgtg gaaaactcag actggtaata aattgtcatt ttttgaaaga atagcgccct
     1921 cttgaacatt atcaatcgca cttaccactt gttgatctga ctttgcatat aagtgaccgt
     1981 aagttcctaa agtgatttga atattcgcat ggcccaatcg ttcttgaata gatagcggtt
     2041 gaatattctg ctcaattaga aatgcaacat gagaatgtcg tagcgcgtga agcttaatcg
     2101 gtttgacacc cgctttttta gcagcttctt ttaaccagtt cgcaaaagaa taaggtggcg
     2161 taaatgttcc gtccaactga gcaacatatt caaaatttcc aatacgtttt tgcaagtcat
     2221 accactgtct gagttttaag gaaagcttct tccccaaccc aatcgttcga taagcacatt
     2281 tagttttggg agtcgaaaag taccaatcat cttttgtatt ataaatcaat gtcttctcaa
     2341 tcgttatcgt gtttttctca aaatctacat tcgaccaaga caaagcttca agttctccaa
     2401 tccgaatgcc agtataaaag agcatttcat acacaatctt ccgatggtgg gtttgaatct
     2461 tatcatcctt caattcattc atcacttttt gaaactcact gtgttcccaa aactcaactt
     2521 tcttattctc agaaggaagc gaagaaacat cttcaacggg atttttagca atcaccccct
     2581 ctttaacagc ccgatccaat acaattttta ggtgccctcg aatccgattg atataagatt
     2641 ttgataacgt ttcgccatta acttttttcc gtgaattacg tgactctgtc tggcttagtt
     2701 caaataacca atcctcaata tcgtgacttg taatatctcg aacacgaaaa tgatagaaaa
     2761 actgcatacg cttttcgaaa atgaattgcg cattctcata tgtttgactt ttgacctgtc
     2821 tctcgtacca ttttacaaac ctatccttgt aaaactcttc gaaagtcatt tgattggtag
     2881 aacacagttg attaggaatt gtcttgttaa aatcatgtgt ttccatgtac ttgtcataag
     2941 caattttggc atctttttgt gaagcataac ctcgtttagt cttctgaacc tttcttccat
     3001 tttcatctat acctagatac gctcggaaga accatttttt tgtcttttta tcttggtaaa
     3061 tatttttaat ttttggcatc gttccattcc tccctgtact tgagaaaagc tactttaata
     3121 gtaccgcgct tgtactgttt attccgcaac ttgaatgtga aaaagatgtt caattactcg
     3181 ggatggcacc acaccaactt ggcgattatt ataaaaatca ataccttcaa tccttgcaag
     3241 atatgccttg ctctctttaa tcattcgtgc agcttgacta ggtttaaagc ccatctctat
     3301 caaaattgca cgatttacca tgaaatcaca ttttgtttcc attctctcac ctcctgattc
     3361 tttactcctt ttaaaataat cctctttata atctattgtt tctcattcga tggttgtgtt
     3421 atactcgtct tgtcgaggcg gagtacgttg cacaacttgt tgtgtaagca gtactttgct
     3481 tttttagtag cttgttttct catttgatat actttgtaat tttcgttcat aatactcaac
     3541 ctcctcctga taatactccg ggtctgcctt catattttgg agaagtttga tctgtcttgg
     3601 attcatttct ccttgttcaa taatcaaagg caacaaggaa gaatgaaacg tttgatcgac
     3661 ctgtgcaata aaaactaatg atggtgaaac accatgaatt aaccaactca tagttttctc
     3721 aaaactttga ggaattgtat ctaaagaaat ggtgattgcg ccataattgc taataaaggc
     3781 tgcccatttg gcatcaactt ttgcacctag atcatttgga tcacggtcat aaaaacaaat
     3841 tgctccatta agtaactcaa agaacagttt ggttaaatca tgggtttttg aaataatctt
     3901 tgccaagctt tgcgctttct cttttcgata ccgtagttca aagcgattct ttacttttgc
     3961 ctcttctaaa ggaattcctc gtcgcttccg ttgttcatgg tccttctgat aaaagcaaaa
     4021 acgacactga ctcttctttg agcctaaata caaggtctca ccatttgatt cattgtttat
     4081 gatatccgta ccgccatgag attcactcac ttgaaaagtg gtccacacat ggcctagtat
     4141 taccttatgc ttaagttctg gaatgctgag actccccaca aaatcatcta aagtaaaatc
     4201 aatccgtgta aagttcccct gataatctaa taccttacga aaaaactgtt gccaatttgt
     4261 ttttcgtgtt tttagccatc ttgctaagtg tttacagcct tgacctgaaa actccatcac
     4321 agttccttta accgcatcgt caatggaata ccgaatcgtg attacttgat tccacacgta
     4381 ttggccaata tagccctttg gcgcataatc cagttcctca aaacgttcaa tgggcatttc
     4441 aataatctct tcaattagct ttaaatgttg attcgagaaa aagtgaatgg ttagataatc
     4501 aatcaaaaca cggttaactg gaacgacctc ttcttgcaaa ctatccaaca caagattcaa
     4561 tttttcttca cttaattgtc tcgttccttt ttctactttc gataataact atctcgaaat
     4621 ccccactttt tctgctaaat atcgttgtgt ccaccccctt tcttctcgag aaactcgaat
     4681 ggcttcaccg agatcatgtt gattaacttg gttcatcgac aaacctcctt ctgctattta
     4741 cttgtcaaag aacctattga acttatttta agtacatttt tattgtacgc ctgtatttat
     4801 tttaagtcaa tatgttttga ctttttttaa gtacacacgt atactaaatt taagaactta
     4861 tcctgaggag gagttttcat ggagatagac aagcaagcag tcggcaatcg aattcggcag
     4921 attcgccaag aattaaagtt gagtatggag aaatttggca aactaattgg tgatttaccg
     4981 cgaagtacag tcaataactg ggaacgtggg atcaaccttc caaaaaccga aacccttcac
     5041 caaatcgcag agataggtca tgtcaccaat gaatatcttt tgtatggtga tcaagagaat
     5101 caatacattt tagaaatgct ccaaaaaaag gcaggtaagc ttgatcctaa gattgaaggt
     5161 ctcatagtag acgaaatcaa acacgctgac cttgttagtg aaaaagaaat ggatcgaatg
     5221 attgaatttt ttattacaaa tctcattcca ccaactgaac aagaccagtt tactttccaa
     5281 tgtatcgatg aaaaaaagca gctttatctt ggttcaacta attttggtaa ggaagcccag
     5341 ctctatttgc aacatgataa tcaaaatcat attctgcaca tgatgccctt taccttctcc
     5401 aactttagtg tggatcgcat actcgtctat ttagcaaatc aaaaatccta ttcctatttt
     5461 gggaaacatt tacccaagga actaggtgag aaagccatcc ttctatactc aattaatcaa
     5521 ttgaccagcg atgtgcgaat tgccccgttg gtctattcag aagaaaccgc ttcttatcag
     5581 tacacagagg acaatcaata tctactagaa cagcaatatc tttatctacc attcgtgatg
     5641 gaagtcgaga aagaacgcct gttaaatgca gcgtatccat catcaaaatg aggtgacaaa
     5701 attgataagc acgtgacaaa gaaaatactg ctaggacact ccccaatggg tagttgtcac
     5761 agtttcctgt tctttgttag ccccctgtta gaaccggggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttaccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctctttta
//
LOCUS       DAYYEF010000029        33883 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000029 DAYYEF010000000
VERSION     DAYYEF010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.029"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(67..186)
                     /locus_tag="ACHA1B_001543"
     CDS             complement(67..186)
                     /locus_tag="ACHA1B_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HFM8702311.1"
                     /translation="MVFQKPLNNFRYIVYYCHTKIKKNKQKETVTKVLSQSLI"
     gene            365..2026
                     /locus_tag="ACHA1B_001544"
     CDS             365..2026
                     /locus_tag="ACHA1B_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM8702312.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2096..2443)
                     /locus_tag="ACHA1B_001545"
     CDS             complement(2096..2443)
                     /locus_tag="ACHA1B_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HFM8702313.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2527..3468
                     /gene="opp3b"
                     /locus_tag="ACHA1B_001546"
     CDS             2527..3468
                     /gene="opp3b"
                     /locus_tag="ACHA1B_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFM8702314.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3469..4512
                     /locus_tag="ACHA1B_001547"
     CDS             3469..4512
                     /locus_tag="ACHA1B_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702315.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4518..5588
                     /locus_tag="ACHA1B_001548"
     CDS             4518..5588
                     /locus_tag="ACHA1B_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702316.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5578..6531
                     /locus_tag="ACHA1B_001549"
     CDS             5578..6531
                     /locus_tag="ACHA1B_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702317.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6543..7553
                     /locus_tag="ACHA1B_001550"
     CDS             6543..7553
                     /locus_tag="ACHA1B_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFM8702318.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7838..8659)
                     /locus_tag="ACHA1B_001551"
     CDS             complement(7838..8659)
                     /locus_tag="ACHA1B_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HFM8702319.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8756..9034)
                     /locus_tag="ACHA1B_001552"
     CDS             complement(8756..9034)
                     /locus_tag="ACHA1B_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702320.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9302..11311
                     /gene="metG"
                     /locus_tag="ACHA1B_001553"
     CDS             9302..11311
                     /gene="metG"
                     /locus_tag="ACHA1B_001553"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HFM8702321.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11790..12377)
                     /locus_tag="ACHA1B_001554"
     CDS             complement(11790..12377)
                     /locus_tag="ACHA1B_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702322.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12552..13874
                     /locus_tag="ACHA1B_001555"
     CDS             12552..13874
                     /locus_tag="ACHA1B_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFM8702323.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            14029..14805
                     /locus_tag="ACHA1B_001556"
     CDS             14029..14805
                     /locus_tag="ACHA1B_001556"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HFM8702324.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14798..15367
                     /gene="rnmV"
                     /locus_tag="ACHA1B_001557"
     CDS             14798..15367
                     /gene="rnmV"
                     /locus_tag="ACHA1B_001557"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043822 - ribonuclease M5 activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HFM8702325.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15360..16244
                     /gene="rsmA"
                     /locus_tag="ACHA1B_001558"
     CDS             15360..16244
                     /gene="rsmA"
                     /locus_tag="ACHA1B_001558"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000179 - rRNA
                     (adenine-N6,N6-)-dimethyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HFM8702326.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16695..17324
                     /locus_tag="ACHA1B_001559"
     CDS             16695..17324
                     /locus_tag="ACHA1B_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702327.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17448..18557)
                     /locus_tag="ACHA1B_001560"
     CDS             complement(17448..18557)
                     /locus_tag="ACHA1B_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702328.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18766..19188
                     /gene="mgsA"
                     /locus_tag="ACHA1B_001561"
     CDS             18766..19188
                     /gene="mgsA"
                     /locus_tag="ACHA1B_001561"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008929 - methylglyoxal synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006007 - glucose catabolic process
                     [Evidence IEA];
                     GO_process: GO:0019242 - methylglyoxal biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HFM8702329.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     regulatory      19375..19473
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01831"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="THF riboswitches regulate genes encoding folate
                     transporters and folate metabolism; They are most commonly
                     found in Clostridiales and Lactobacillales; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="tetrahydrofolate"
                     /db_xref="RFAM:RF01831"
     gene            19511..20047
                     /locus_tag="ACHA1B_001562"
     CDS             19511..20047
                     /locus_tag="ACHA1B_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HFM8702330.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20087..21850)
                     /locus_tag="ACHA1B_001563"
     CDS             complement(20087..21850)
                     /locus_tag="ACHA1B_001563"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702331.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21853..23568)
                     /locus_tag="ACHA1B_001564"
     CDS             complement(21853..23568)
                     /locus_tag="ACHA1B_001564"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702332.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(24347..24571)
                     /locus_tag="ACHA1B_001565"
     CDS             complement(24347..24571)
                     /locus_tag="ACHA1B_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702333.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24762..27539
                     /locus_tag="ACHA1B_001566"
     CDS             24762..27539
                     /locus_tag="ACHA1B_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFM8702334.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27620..28039
                     /locus_tag="ACHA1B_001567"
     CDS             27620..28039
                     /locus_tag="ACHA1B_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM8702335.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            28051..28521
                     /locus_tag="ACHA1B_001568"
     CDS             28051..28521
                     /locus_tag="ACHA1B_001568"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM8702336.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28538..29317
                     /locus_tag="ACHA1B_001569"
     CDS             28538..29317
                     /locus_tag="ACHA1B_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFM8702337.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            29304..30125
                     /locus_tag="ACHA1B_001570"
     CDS             29304..30125
                     /locus_tag="ACHA1B_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFM8702338.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            30142..31191
                     /locus_tag="ACHA1B_001571"
     CDS             30142..31191
                     /locus_tag="ACHA1B_001571"
                     /EC_number="3.5.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFM8702339.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            31204..32208
                     /locus_tag="ACHA1B_001572"
     CDS             31204..32208
                     /locus_tag="ACHA1B_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFM8702340.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32841..33860
                     /locus_tag="ACHA1B_001573"
     CDS             32841..33860
                     /locus_tag="ACHA1B_001573"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009331 - glycerol-3-phosphate
                     dehydrogenase (FAD) complex [Evidence IEA];
                     GO_function: GO:0047952 - glycerol-3-phosphate
                     dehydrogenase [NAD(P)+] activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0046168 - glycerol-3-phosphate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HFM8702341.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT        11059 a         6003 c         6919 g         9902 t
ORIGIN      
        1 tggctttcta catttttgca taaatttggc ttaataccga gaaactggct tttgaacacc
       61 gtttattcag ataagggact gtgacaagac ttttgtcaca gtttcttttt gtttattctt
      121 ttttatcttt gtatggcaat aatagacaat ataacgaaaa ttatttaatg gcttttggaa
      181 gaccatggaa aaccttgtac aaagctattt tttctgaaaa attccttgaa acctcacgaa
      241 aaaatcatta ttttatgaaa aagacaaaaa aaagtgttga ttttttaata attattcatt
      301 aaactcttaa acaacttcag aaaatattaa ttattctgaa aattccaata aaggggtacg
      361 taaaatgaaa aagaaattta catttggttt ggttgcggta tgcggccttg tacttgctgg
      421 atgttatggc ggcagttcag ccacaagcag tagttcagca aaaagcggtt cagcagatgg
      481 aggaggcgta tttaacttag tcgtgcctca agaaatgcct acagctgact tatcagttgc
      541 aacagataca atcagtttta cagcattgaa taacgtttat gaaggaattt accgtcttga
      601 tgaagacagc aaaccacagc cggcaggagc tagcgagttg gcagaagtca gtgaagacgg
      661 attaacttac aaaatcaaat tacgagaaga cgcaaaatgg tcaaatggtg atcctgttac
      721 agcagcggat tacgtttatg gctggcaacg aacagtagac ccagctacag cttctgaata
      781 tgcttacctg tatgcgccag ttgaaaatgc agaagacatt acagctggaa agaaagataa
      841 atcagaacta gggatcaaag cagttggtga ctatgaatta gaaatcaaat tgacgaaaca
      901 aacaccatat ttccaatatc tgcttgcttt cccatcattt ttcccacaaa aacaatccgt
      961 agtggaagaa aatggggatg cctatgcatc tgcaagtgat aaagctgttt ataatggacc
     1021 attcacatta gaagattttg atggaccagg aacagataca gaatggactt ataagaaaaa
     1081 tgatcattac tgggacaaag atacagtaaa actttctgaa atcaaagtca gtgtagtaaa
     1141 agaatcttct actgcattga acttattcaa agatggccaa gcagatgacg tgatcttgtc
     1201 tggtgagtta gcacagcaaa acgcaaacga tccagcttat acttctgtta aagaagcgcg
     1261 gacaagctat atcgaattca atcaacgtga aaagaattca ccattcaaca atgtgaacct
     1321 aagaaaagct atttcttatt ctatcgatcg tgaagcttta gtaaaacaag tactaggtga
     1381 cggatcagtt gtctctacag gattgatccc atcagatatg gtaaaaagtc caacaacgaa
     1441 cgaagacttt gcaaaagaag ctggaaaatt agtttcttat gacaaagata aagcaaaaga
     1501 atattgggaa aaagcgaaaa aagaattggg cgttgattct ttagaatttg atttgatggc
     1561 ttctgatgat gattcatcga aaaaagtaat cgaatatgtt caaaactcaa tccaagaaaa
     1621 cttggatggc gtaacagtca aaccaacacc tgttccattc tctgtacgtc ttgaccgctc
     1681 aacttcgggt gattttgacg cagtactagg cggatgggct gctgactatg cagacccaag
     1741 cagctttact gatttgtttg tcacaggtaa ttcatacaac cgtggtcgct ggagcaatgc
     1801 agaatatgac gaagcagtta aagcagcttc atcaacagac gctggcgatg aacaagcccg
     1861 ttgggatgat ttccaaaaag caatcaagat catctctgat gatatgggtg tcgttccggt
     1921 gtaccaaaaa gcagaaggtc acctagtgaa tgaaaaaatc aaaggtatcg ttcaccatgc
     1981 ggcaggcgct tcatgggatt acaaatggac atacgttgaa gaataatcgt taataccgtg
     2041 agcatgagaa aaaacgaggc tgcggcaaat gtcgcaacct cgttctcata ttcacttatc
     2101 ctaacaaaga aaaaagcatg aaaatagcag aaagagcaat tagtattccg gcaatgatca
     2161 gccaaaagct gtacataccg tagctggcag acgagagcga ggaaaattct ggttttttct
     2221 ttcggttcct tgttcgtgca agatggaccg atcgctgaaa atgatcgaag aaacccgaag
     2281 aaaagaccca taaaaaaccg ccgataatca gaaacggcaa tgaccataag aatagatcat
     2341 tagataattg aatgagtgta aaggaatggt tgatgagatt ttttattaaa ataaccagaa
     2401 tcagtagaaa agctactgcg taggggatag attttttttt catttgattg ctcctttatt
     2461 tttggttcat tatctaataa tgtagcgaaa catctgtcag aagtcaaaag ctagggggaa
     2521 acattagtga atagttatat caaatatgta ttaaaacgtg tctttttcat gatcatcacg
     2581 ctttggttaa ttgcaacaat cacctttttc ttgatgcaat tgctgccggg cacgccatat
     2641 acgaatcagg aacgtttgag tcctgaaaca atcgagatgc taaataaaca agtcggtttg
     2701 gataaaccag ttatcgtaca atatgggatt tatctttcta atttgcttca aggagatttt
     2761 ggaatttcct tccaatttaa aaaccagcca gtcgcacatt tgttagctgg aagaatcgga
     2821 ccatccttgc agttagggtt acaggcaatt atctttggaa cagtcctagg gacgatttta
     2881 ggaacgatct ctgccatgaa gcaaaataca tgggcagata catcttctac actcgtagcg
     2941 atattaggtc gttccattcc aaactttgta tttgctgttt tattacaata tatctttgca
     3001 atcaaattac aagttttgcc aatcgcaaaa tgggatggct ttgtgtacac aatcttacca
     3061 acaattgcgt tggccatgtc gccgcttgct gactctgctc ggtttatccg tacggaaatg
     3121 gtggaagtac tgcatagtga ttatgtggaa ttagcaaaag caaaaggatt gagccgttgg
     3181 gaaatcgcct ttaaacatgg tcttcgaaat agtttgattc cattgatgac tttattagga
     3241 ccgttagctg tagcattgat gaccggatca ctggtggtag aaaatatctt tgctattcct
     3301 ggtatcgggg aacaattcgt taagtcaatc acaacaaatg attatcctac gatcatggct
     3361 gtaacgatcc tttactcatt tatgctgatt tttgttattt tgatcgtgga tctattgtac
     3421 ggtctagttg atccaagaat tcgtgtttca gaagggagcc gaggataaat ggaaatgata
     3481 ccaaagcgtt atgaaacagt tgcagatatc cctgcggatg aatttcttcc attacaaaaa
     3541 aataccgaag aagaacgtga acagattact gcaccttctt tgaattttat ccaagattca
     3601 tggcgccgtt taaagaaaaa caaagctgcc gttatttcaa tggttttact attggtcatc
     3661 attttgatct ctgtgatcac aatctttgtt tctcctcatg atccaactgc ccaaaacgtg
     3721 gcttatatca atttgcctcc tcgtattccg ggaatcaata tcgatggatt gaatggaaaa
     3781 gcaatggttg gtggtgaact tgttgataaa tatgctcaag caaacgtccc ttcaaacgta
     3841 aatttctttt taggaacaga cggtttggga cgtgatgtat taagccgctt atttatggga
     3901 atgagaatct cgttgctgat cgcatttatt gctgcattac tagatgtaac gattggtgta
     3961 gcttacgggt tggtttctgg tttgttaggc ggacgtgtcg ataacgtgat gcaacgtttt
     4021 ttggaaatct tatcaggaat tccaaacctc gttgtcatga ttttgatgtt ggtcgttttt
     4081 gaaccaggaa ttttttcaat cgtggctgct atggccatca caaactggat accaatggca
     4141 cgtatcgttc gtgcacaaac aatgaaatta aaagatcaag aatatgtttt agctggattg
     4201 acattaggtg aatcaagaat gaaaattgca ttcaaacata ttttgccgaa tatctctagt
     4261 gtcattatta ttcaaatgat gtttagtatt ccatctgcta ttttcttcga agccttttta
     4321 agctttatcg gtttaggtct tacgcctccg tcagcttcat taggaacgat gttgagcgaa
     4381 gggtacaaga cattcctgta tctgccttat ctattatgga ttccggcagt aactttatcg
     4441 gttatcatga ttggctttaa cttacttgct gatggattgc gtgatgcctt tgatcctaaa
     4501 atgaaagagt gaagacgatg acgaaaattt tagaagtgaa agacttagaa atctcttttg
     4561 atacgtatgc tggaaaggta cgagcgattc gcggtgtcaa ttttcatttg aataaaggag
     4621 aaacattggc gatcgttggg gaatctggaa gtggaaaatc agtgacgacc agaagcatca
     4681 tgcgcttgct gtcaagcaac gccaatatag atgctggtca aatcctcttt aaaggtaacg
     4741 atatcgttgg aaaatcagaa agagagatgc aaaaaatccg tggtaaagaa atagcgatga
     4801 ttttccaaga tccaatgacc tctttagatc cgacgatgcc cattgggaag caagtcgctg
     4861 agtcccttag aaagcataat aaagtttcaa aaaaagaggg acaaaaagct gcattagaat
     4921 tgcttaaatt agttggaata cccgaagctg agaaacgtat caacagttat ccgcatcagt
     4981 tctcaggagg tcagcgtcaa cggatcgtga tcgcgattgc actggtatgt tatccggaaa
     5041 tcctgattgc tgatgaacct acaacagcgc ttgatgtgac tattcaagca cagattttgg
     5101 agctgctgaa agaaattcag acaaaaatcg atacatcaat tatctttatc actcatgacc
     5161 ttggtgtagt agcgaatgtc gctgatcgtg tcgctgtcat gtatggagga agaatcgttg
     5221 aagttggaac atcggaagaa attttctaca acccgcaaca tccctatact tggggactgc
     5281 ttggttcaat gccgacatta gatagtgcga acgatcgatt gtatgctatt cctggttctc
     5341 caccggattt attgaacccg ccaaaaggag acgcattcta tccaagaaat gaattcgcga
     5401 tgaaaatcga tgcagaacaa gaaccaccat tttttgaact atcaaaaaca cacaaggcag
     5461 caacttggct acttgctccg caggcaccca aagtgacacc gccagaagaa atccaacgtc
     5521 gctgggctat ctttaaagag aaacaaaaac atacttacgg tcaaggagga attgctgatg
     5581 ccaaataaac tacttgaagt taaaggattg aaacagtatt tcaatgtagg aaaaaagaat
     5641 gaagtacatg ctgtaaatga catcagcttt cacatttatg aaggagaaac attcggttta
     5701 gttggagaat ctggaagcgg aaaatccact actggccgta cgatcattcg cttgaatgaa
     5761 cctactgatg gtgagatatt attcgacggt caagatataa cgaagatcaa agataaaaaa
     5821 ggtttgacga aattccggca tgatgttcag atgatctttc aagatccata cgcttcgttg
     5881 aatcctcgta tgaaagtcag agatatcatt gccgaaggaa ttgatgttaa tggactagct
     5941 aaatcatctg aagagcgtgc aaaaaaagtc gatgatctat tgagaactgt tggattgaat
     6001 ccaagccacg gtactcgtta tcctcatgaa ttttcaggtg ggcaacgcca gcgtattggt
     6061 attgcacgag cattggcagt aaaaccgcgt tttatcattt gtgatgaacc aatttctgca
     6121 ctagatgtgt cgatccaagc ccaagtggtc aatttgttgc aagatctcca aaaagaacat
     6181 caattgacct atctatttat tgcacatgat ttgtcgatgg ttaaacatat tagtgaccga
     6241 atcggtgtaa tgcataacgg cttgttatta gagatgggaa caagtgatga aatctataat
     6301 cacggtgttc atccttatac agaaagtttg ttatctgcta ttcctctacc agatccagac
     6361 catgagagaa aacgcagaag aatcaaatat caacctgaac cagatgacgg acaagtacgt
     6421 caacttcgtg aaatcgcacc agaacatttt gtctatgcaa ctgagcagga agtcccatat
     6481 tacgcaaaaa aactaaaacg acaaaaggaa tctcttctgg ttgctaacta ggagggacat
     6541 agatgctaaa agcttttaaa ttccgtatgt atccgacaga agaacaaaaa cagcaattga
     6601 ttcgtacttt tggatgtgct cgatttacct ataaccattt gctgaaaaag cggcagaaaa
     6661 gttggcaaca aacaggagta gccaattttt cgctcacacc cgctacatta aaaaaagaat
     6721 acccattctt aaaagaagta gacagtcttg ctttagcaaa tgcacagctt aatttggatc
     6781 gggcttttcg caattatttc aagggacgtg ccagcttccc aaagcttaaa acgaaaaaaa
     6841 gtatgtggca atcttatacg accaacaacc aaacccgtac gatctatctg gaaaatggct
     6901 acttaaagtt accaaaacaa aaagaactaa tcaagataaa tcagcatcgg ccagttgaag
     6961 gatcgattcg ctccgctacg atttctgctc gatataatga agaattttat gtcgcactac
     7021 tttgtgatgt ttcgccagta aaaaaagaat ctttagctaa atggatcggg atcgcctatc
     7081 atccgaagac attgatccaa acatctcgac ctctagaagt aactttacca aaatttcacc
     7141 agacagaaga aaagctgcaa catgcacagc ggaaattgaa tgtgaaagtc cgctccgctc
     7201 accatagaaa gatcaggtta gatcaggcaa gcaattatca gaaacaaaag agaaaagtaa
     7261 tggatcttta tctgaaacaa aagaaccagc gagaagatta tcttgaacaa ttatctggga
     7321 aattggtcaa acaatatgac tacttatttg tagaatcttt tccaaaagaa gaggcacatg
     7381 ctgatttttc tattcacgac tggcataaat taataacaaa attgcgttat aagtcccaat
     7441 ggtataataa aaaatttctt ttgatcaata ccgacggagc agaagaaagc aattccgtaa
     7501 gaaagagcca agtagtagaa aaaatgggca gacattcggt tatcaaggga taaaaaatga
     7561 atgaaactga taggagcgtt agggttagcc ttgttaataa aaagtcttaa tgacttttgt
     7621 ttctaggaat ttttcttttg aagaaaagct cactaattat gacaaaccaa taaaacaata
     7681 gcagaaaaag ttcgtacgag ctttttctgc tattgttaat tttttattca gaaagtttac
     7741 gaatacatca aaattctgaa acaaaaaacg taactcacaa agagttgttt ttgcgttttt
     7801 tcttgaatga ttaggtctga atcttttgct cacaacctta ttcatggtgc cccggcttga
     7861 gctgatagat ttttgaagga cggccgattc ctacaggacg ttcaccgatc tcatcgaaat
     7921 attggagcat agctttctta aaattggaat gatcgatcgt tttataatcg atccctaaga
     7981 atttagcaaa tacttttcga gcttccgtaa tcgtgaaatc tttacctaaa acttgtagaa
     8041 cttgcggctc gtgttccatt ttattgacta cacggttgaa tgctttcaag atgatttgac
     8101 tatggtcaaa agccaaagta tctttgccag aagactctcc agtgactaaa tcaagcgaga
     8161 tagccacttc tccgctagat aaatggatct tgttactatg acgttctagt gtgaaccagc
     8221 gtacttcctt ggcatcatct ccggcgatta gcggttcttc tccaataaag gctaagtagc
     8281 tgactgtgac gacccagcct cgcggatctc gattaggcgt actgaatgta tgcagttgct
     8341 caatattttc ttttgaaata accacaccag tttcttcctt tgtttctctt aagacgcttt
     8401 ctccagttga ctcatccttt tggacaaagc caccaggcaa tgcccatgaa tttcgataag
     8461 gatgcccttt tctttggatc aacaaaactt tcagctgatc ttcttctttg ttatagcaca
     8521 tcagtacgat atcgacagtc aaagagggct tgtcatattc tggacgttcc tgtttttgat
     8581 accagttaag aaattcttct tcacttgctt tatgttcata atataatttt tcttcttctt
     8641 tagaagcaaa acggttcatc tgaccacctc cattgacagt aaaagtactt tttaccttat
     8701 tgtagcagac tctgaaaaaa aaccaaggat ttacttgaaa aatctaggtt atcatttaaa
     8761 tatgaaaaat aaatggaagt atgagattga ataaaaagaa aagcagataa aacggcaata
     8821 ctttataccg ctcttcacga atggcaaaga agccacaaat aacgatatat acgtcaatga
     8881 taaaacgcaa aatccaagct gctgtcataa aactgttcaa atgcccatgg aggttaaaat
     8941 aaccatacat acgaatataa aaatagctga atattaaatg tgctaatgaa agaaaagcaa
     9001 tactaagtgt aaaaaaaaga tgtttcttct gcatgattgt tccagtccct tactaagata
     9061 gatagtcttt attataccac gtgtgagggg agaaataaaa agccgttttt tagtagatat
     9121 gaaacaaaac aaaaacccgc atttattcaa cctattcatc cttttaaagg atagattgaa
     9181 cgtagataga agtcgtttat ccagtctttt tcattttgaa aaaaagctaa cagcatgctt
     9241 tttttatggt atactagcaa ggaaacgaat tcgcatcatg cgataaagga ggaagagccc
     9301 cgtggcagaa aaggaaactt tttatatcac tacgccaatc tattatccaa gcggcaaact
     9361 tcatatcggc aactcgtata ctacgattgc atgtgacgca attgctcgtt ataaacggtt
     9421 gatgggcttt gatgtgtttt atctcactgg agtggatgaa catggtcaaa aaatcgaaac
     9481 aaaagcagaa gaactaggtg taaaaccgca agaatatgta gataaaatgg cggctgatgt
     9541 caagaaatta tggaaaacgc ttgatatcag ttatgataaa ttcattcgca cgacagatga
     9601 ttaccataaa gcagctgttc aaaaaatatt tgatcgttta ttagaacagg gagatattta
     9661 cttaggtgaa tatgaaggct ggtactctgt ttctgacgaa gaattcttta cagaaacaca
     9721 acttgcagaa gtgtacaaag atgacgaagg taacgtgatc ggtggtaaag cgccaagtgg
     9781 acacgaagta gaattggtaa aagaagaatc atacttcttc cgcatgagca aatacgcaga
     9841 ccgtctattg gaatactatg aagaacatcc cgaattcatc cagccagaat ctcgtaaaaa
     9901 cgaaatgatc aacaacttta tcaaaccagg attagaggat cttgcagttt cacgaacaac
     9961 ttttacttgg ggagtaccag tcaagagtga tccgaaacat gtggtgtatg tatggatcga
    10021 tgcattatcc aattatatta ctgcactagg atatggctcc gaagatgaaa gtctattcga
    10081 aaaatactgg cctgcagatg ttcagatggt cggtaaagaa atcgttcgct ttcatacgat
    10141 ctattggcca atcatgctga tggcccttga tttgcctcta cctaaaaaag tatttgggca
    10201 tggctggcta ttgatgaaag acggaaaaat gtctaaatca aaaggaaatg tcgtttatcc
    10261 tgaaatgctt gtggaacgtt atggtttaga tgcactccgt tattatttgc ttcgtgctgt
    10321 tccgtttggg tcagatggtg tctttacgcc agaagatttt gtttcccgtg tcaattatga
    10381 tctggcaaat gatctaggga acttattgaa tcgaacgatt gctatgatca acaaatattg
    10441 tgatggactc gttcctgact atgcctcact tgtcactcca tttgatagtg aactgtctac
    10501 gacggctgct aacgttgtcg gacgttacca tgatgcaatg gaaaaaatgg aattcaatac
    10561 agcattggct gaaatctggg tgctgatttc tcgtgcaaac aaatacattg atgaaacaga
    10621 accatgggta ttagcaaaag acgaagaaaa gaaagctgaa ttgaatagtg tcatgatcca
    10681 tttagctgaa tctttgcgta tcgcagcgat attacttcag ccaatcatga cagaaacgcc
    10741 agagaagatc ttcaatcaac taggattgga ctctgaaaca atgaatcttg aaggattaca
    10801 ctttggcgaa tttccttcag gaacaaaagt agttgcaaaa ggtacaccaa tcttcccacg
    10861 tttagatatg gaagaagaag ttgcttttat tcaagaaaaa atgtctgaag gtactcaaac
    10921 aaacgaagat acagtcaaat gggatccaga agaaacagaa cttgtttcaa cgaaagaaaa
    10981 acaaatcaaa tttgatgtat ttgaaaaagt agaactaaaa gtagcagaag tcatcaactg
    11041 tcaaaaagta gaaggggcag ataagttgct gcaattccga ctagatgctg gagacagcca
    11101 agaccgtcaa atcttgtcag gaatcgctga attttatcct gatccaagcg aattgatcgg
    11161 gaaaaaagtc gtcattgtag caaatctgaa accacgaaag atgcgtggac aaatcagtca
    11221 aggaatgatc ctttctgcag aagcaccaga tggctcttta caagtaatcg aagcaccaaa
    11281 atccatgcca aatggctcag aaatcgcata gaaattcaaa gggggtatga cactagttgt
    11341 gtcatacccc ctttttccga aatttgagaa gcaattttcg taaattcctt cttattactt
    11401 gaagccaatc atataataca gaaacagaga actatccaaa ataaatccta gaaaaagaag
    11461 tacgagcttc gctgattttt gttaatttag aataatacta ataggaatcg taaaaacaga
    11521 aaaaaagcat aatgataaag ggtcgggcag attttaattg attcatctgg tactcttttt
    11581 tattgtcctt acattcataa agtttgaatg caatgacttt attacatcta tatttatatc
    11641 taacagtagc gttgatgtgt taattataag ttctatcact ttatgttcaa ttagtttgtg
    11701 ctcttatatg tgtgattgaa aatatagata aaaaaacaat catcggcttt gacttcgatg
    11761 attgttttct ttattttgta aaaatcctat cacttgattt tatggtaacc ttttattttt
    11821 gtcttcaaac ggcttggtaa gagagcagta agcagtgcaa atgggatcga aaagacatac
    11881 cagaaaatcg tacgtccgat accataatgt tgatagagct ttgtcaacat cacgtgtaac
    11941 aagatcaacc ctaaaagcaa ggagccagct ataaaccaat gattatccca atgcatgact
    12001 tcactaagtg ccatcactcc aaaaggatag aaataaaaat agatcccgac taaggtcatc
    12061 cgccagttct ttgtaaatgt tccgatattc aataaaaaga aaatcgctga aagcaaaata
    12121 ccgataggcg gaaaaagccc aaccaaaaag gaatacaaca tcccccacaa gatcatcaca
    12181 ggacctttga tcaatgcaac gattgcgatg aacaaagtca gcaatattag tttttgtgat
    12241 aacgttgcaa cagtcattaa tccaaataaa attaatgtga accaatgcca atgggactgc
    12301 tgttgttctt tacgggaaaa atcgacccgg ttggataaat aatctgctaa tttcggataa
    12361 gaacgcttaa aatccataaa ctgttcctcc ttcgtggaaa aggtaggttt agtatacgaa
    12421 aaataaaaaa gaaatacatc cgtcttaaga gggagttttt cactgaaagt ggagaaaaaa
    12481 gaatggtaaa ttaaaatatt ctcagttata ctgaaaatta taccaaattt caaagaagaa
    12541 agaggatggg aatgaaaggc aaactaaaac gagaaatcaa tctgtttggc gcattagcta
    12601 ccgttatggg aaccgtgatc ggtgcaggcg tcttcttcaa aactgctgct gttactgcta
    12661 gtactcagtc tacaagtttg acattgctag cttggctttt gggtggtttc ttaacgatct
    12721 gtgctggatt gacagtggct gaattagcta cagcaatccc ggaaactggt ggagctgtaa
    12781 aatatattga agctgcgtat ggaaaattgc ccagcttttt attaggatgg gcgcaaagct
    12841 tgatttactt tcctgctaat attgctgcat tatcgattat ctttgcgaca caattgacga
    12901 acttattaca attatctacc gattatcttt tgttgattgc agtgatcacc gctgtttctg
    12961 tgacagggtt gaatttgtta gggacaaaag tcggtgcttc tgtacaatca gtgacgttga
    13021 ttgttaaatt aataccaatt gctgtgattg tcatatgggg attattgacc ccaggacaag
    13081 gaactgtcca gttatttcca atcgaagctg gaaaagatgt tacttttgtc gaaggattga
    13141 gcagtgcgtt gttagcaacg ttgtttgctt atgacggctg gttaggtgtc ggtgcaatgg
    13201 caggggaaat gaaacggccg gaaaaagatt tgcctaaagc aattattctt ggtttgagtt
    13261 ttgtaacagt cgtttatcta ttgatcaatt ttgttttttt gaaaactttg ccgattgatc
    13321 atcttgccgg taatttgaat gcagcttctg aagcatcaga cgtcattttt ggaggaatcg
    13381 gtggaaagct ggtcactatt gggatcttga tctcggtata cggtgcattg aacggttata
    13441 cactaactgg gatccgcgtg ccttatgcga tggctttaga agacgagcta cctttcagta
    13501 aacagctgac aaagctttca aagaagttta cggttcctta tgttcctgcg gttttccagt
    13561 tagcagtagc ttgtattatg atgagccttg gttctttcga ctttttaaca gacatgttga
    13621 tttttgtgat gtggctattc agtttactga tttttatcgg tgtctttatt ttaagaaaaa
    13681 aagcgccgga attgccacgt ccatataaag taccacttta tccaatcgtt ccgattattg
    13741 cgattctcgg tgctattttc attttaggta tgacgatgat gacgcaaacg aaattagcat
    13801 tgatcggtat aggtgttacc ttgataggta tcccagtcta ttatcaaaaa aagaaaaaac
    13861 gctcagaaga gtaaaatatt tcaacaacag acagaaaaag tacgaactag gtcctctaga
    13921 tcttcgtgct ttttctattt caataaaaca agttcttcta ttttgatttt tgctacttct
    13981 gcaagtagtg cttatgtgct aaagtaagaa tgaaaaggag agataaacat gatatttgat
    14041 tctcataccc atttaaatgc tgaacagttc aatgaagata ttccagaaac gattcagcga
    14101 gcacaagaaa tgggggtaac gaaaatggcg gtcgtgggct tcgatacgcc aacgattgaa
    14161 aagtctttgc aattaagcca tgactatcca aatatataca gtattatcgg ctggcatccg
    14221 acagaggctg gcagttatac gaaagaaatc gaaaataaat tacaagaaca attgacttta
    14281 ccaaaggttg tagcattagg ggaaattggc ttggattatc attggatgga agacccgaaa
    14341 gaagtccaag ataaagtatt tcgcagacag attgctatcg caaaagaaat gaacctacca
    14401 atcagtattc atactagaga agcacttgaa gacacgtatc aaatcctaaa agaagaagat
    14461 gttcgagata tcggtggaat catgcatagt ttcagtggtg attatgaatg ggcaaaacga
    14521 tttcttgact tagggatgca tatttcattt agcggtgtcg tcactttcaa aaaagcatta
    14581 gacgtccaag aggctgcagc aaatgtacca atcgaacgat tacttgtgga aacagatgcc
    14641 ccttatctgg caccagttcc ttttagagga aagcgaaatg aaccaggcta tactcgttat
    14701 acagtagaaa agattgctga acttcggaat cttccgacag aagaagtggc tgcccaaaca
    14761 tggacaaatg cgcaccgatt atttggtcta agcgaacatg gataagatga agatccaaga
    14821 gattatagtc gttgaaggaa aagacgatac aagaaggctg cgggaagtag ttgatgcaga
    14881 tacgatagaa acaatagggt ctgcaatcaa tgaagagatc ctgatgcaaa ttgaacatgc
    14941 ccaagagact cgtggagtga tcgtttttac cgatcctgat ttttcaggag aaaaaataag
    15001 aaaaatcatt atggaagctg ttcctcaggc aaaacatgct tttttgccgc gcacacaagc
    15061 taaaccaaag aaaaagggaa gccttggtgt cgagcatgca agtgatgctg ctattttaga
    15121 agcattgaaa aaggtcgtga cgccagacat ttcccaaacg gctgtttctg aaatcactag
    15181 acaagacctt ttagactatg gtttaatagc tggggcacaa gcaaaagaaa aacgagaaaa
    15241 actaggtgac gagttgcgca tcggttacac gaacggcaaa caattggaaa aacgtttgaa
    15301 gatgtttcgt attacgccga aagaactcgc ccaagcaatg aaaatagtgg aggaacaaca
    15361 tgagtgaata tcgtgaaatt gcgacaccct ctagaacaaa agagatttta ttgaaacatg
    15421 gtttttcatt taaaaaaagt ttaggacaaa attttctgac tgaaccaaat attttaagga
    15481 aaatcgtaga aactgcgcaa atagatgaac atacgaacgt gatcgaagtt ggaccaggaa
    15541 tcggtgcatt gacggaacaa ttagccaagc atgcaaaaca agtcgtagca tttgagatcg
    15601 atgatcgttt gatccctgta ttggctgata cgatgcaacc ctatgacaat gtgactattg
    15661 tacatcaaga tattttaaag accgatttgt caacagctgt tagagaaaca tttcatgagg
    15721 agcttccgtt aaaagtcgta gcgaatttac cttactatat tacgacaccg atcatgatgc
    15781 attttcttga atcagatttg gttgtggatg aactagtcgt catgatgcaa aaagaagtag
    15841 ctgatcgtat ctctgctgaa ccaggaacga aagcttatgg ttcattatcg attgctgttc
    15901 aatattatat ggaagccagt ttagcattca tcgtaccaaa aacagtattt gtccctcagc
    15961 caaatgtaga ttcagcgatt ttgaaactga caagaagaga tataccggca gtcgaagtga
    16021 cagacgaaaa agcatttttc cgattgacaa aagcggcatt tcagcaaaga agaaaaacgc
    16081 tttggaataa cttgcagcat tcgtatggca aagatgacca gacaaaagca tggttagcaa
    16141 aaagcttgga aacagctgga atcgatccaa aacgtcgtgg ggagactttg tcattacaag
    16201 aattcgccgc attaagcaat gcgatgtcag aaaatatgca gtaaaaaaag aggttgtgac
    16261 agaagttgtg aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagttc
    16321 ctcatgtttt tcgtttgttt gggcttatta ccgcagatgc aagcttttga acaccgttta
    16381 agaaagaggt tgtgggcctg ccgtttaact ctaagtcaca aggaacaatt tcaaaaaaca
    16441 gcttctcatg tttttgagtt agttggtctt attacttgat gcaagctttt gaccactatt
    16501 atgccgaaca aggagatgtg acacaaattt tgtcacatct cctatttttg tttcttgatc
    16561 aaaaaattct tatacttgat actcacactc attttgtatg gatttagaaa agaatatgtg
    16621 tcttgacagt tattagtaag tgagttatac taagtcgaca tttatgtgtc aagacatatt
    16681 aggagagaga aaaaatgaga aaaaattcag ttcgaaaact aacgatttct gctttattga
    16741 ttgggatggg ggtcattatc ccaatggtca tgcctaaaat catgattcca ccagcttcct
    16801 ttactttggc gtctcatgtg ccattattta ttgcgatgtt ttttacacca ggagttgcag
    16861 tggctgttgc gctaggtacg acatttggtt tctttttaac aacgccggtt atcatcgcat
    16921 tgcgagcatt gtcacatctt gtgtttgcgt tgattggggc ttggtacttg caaaagcatc
    16981 cgagtatcgt tttaaaaaat ggacagttta cttttgctaa ttggcgtttc caagggttca
    17041 attttgtgat cggtgtgatt cattctttag cagaaatgct agtagtcagc atcttttact
    17101 ttattggtaa tatgcctgaa acatattatt ctcaaggata tttttataca gtattcatct
    17161 tgatggggat tggtgggctt atccacagtt tagttgatta taatattgct tattttatag
    17221 caggaacact cagcaaatat tttgatatcc ccgtatttac ggcagcaaaa aaagaaaatc
    17281 ggaaagagtc gattcaaggg tacgcgaaga aaacgacata ttagacatga tctctcaaaa
    17341 aaaaaactct catctagtaa tggataataa atcctctaag atgagagttt tttgtcctaa
    17401 aaagagctgc accaacatct tctggcacag ctctaacagg gggcaattta tggaagtttg
    17461 atgacttgtt ctgtttcttt atcaaagaag tggcctttgc tgatgttgaa ggcaaggtcg
    17521 actatttcgc ctggtttatg gaaatctctt gcatctactt ttgagatgaa ctcagtagaa
    17581 ccagtttttg tgtaaagcat cgtttcagct ccaagtaatt cggaaacgac aacttctgat
    17641 ttcactacgg cttcaggtga agcttcaagg gctacttgtt cactgtggat gtcttctgga
    17701 cgaataccga agataacttc ttttccttca taaccttttt caactaatac tttgtttttt
    17761 ccttcaggaa tacgaagctt aagcccatgt ccatctgtga taacaccatt tttcaatgtc
    17821 acattaaaga agttcatggc aggagatcca ataaagccgg caacgaacat attgacgggt
    17881 gtatcataaa cttctttcgg tgtaccgatt tgttggataa atccgtcttt catgataacg
    17941 attcggtcag ccatagtcat tgcttctgtc tgatcgtgag taacatagat ggtcgttgtt
    18001 tcaagacgct ggtgaagttt ggcaatctca gcacgcatgg ctacacgtaa tttagcatct
    18061 aaatttgata atggctcatc cattaagaag acttttgcat cccgaacgat tgcccgtccc
    18121 aatgccacac gttggcgttg tccaccagat aaagcagctg gttttcgttt caagtattct
    18181 gtcagaccta agatctctgc tgcattgtcc acacgttttt tgatgtctgc tttatcatat
    18241 ttacgtaatt tcaagccaaa agccatatta tcaaaaacag tcatatgagg atacaatgcg
    18301 tagttttgga aaaccatggc aatatcacgg tctttaggtg ccacgtcatt catgactttt
    18361 ccgccgatat ttagttctcc ttcagagata tcttccagtc ccgcgatcat tcgcaaagta
    18421 gttgactttc cacaaccgga aggaccaaca aaaacgataa attcacggtc tttgattgat
    18481 agattaaaat cagttacaga ataattttct gcattgtcat attttttata tacgtttttc
    18541 agagccattt ctaccataat acgttccaca ctttcttttt tagttttatt aactatttaa
    18601 agtataaatg aaagcgttaa ctaacttcaa tgtcatgttg aacaagaatt ttttcttttt
    18661 tttgtcaatg tgctagtttt aagctttaat aaatatccat aagaaataaa aactgataca
    18721 ctggagtaaa taagtatgtt aacaatatca aaaggagtgt ctcttatgaa aatcgctttg
    18781 atcgctcatg accgaaaaaa acctatgatg gtgaaattag caacagcgta taaaacaata
    18841 ttggaaaaac atgaactttt tgctaccggg acgactgggc agaggatcac ggaagcaacc
    18901 ggcttgccga tccatcggtt taaatccgga ccgttaggcg gggatcagca aattggagcc
    18961 atgatttcgg aggatcagtt agatttggtg atttttcttc gagacccgct ggctgcacag
    19021 ccccatgaac cagatgtaac agcacttatc cgtttatctg atgtctatga gattccgtta
    19081 gctacgaata tcggaacagc tgaggtgcta ctaagaggac tggaagccgg cttcctagat
    19141 tttcgaagaa tcgtccatga aatagacaag catccacttt cattttgatg gataagcgta
    19201 tggaaaaata acgtttaatg ttcgcctata tgtagctata aaagctaaac aaactgataa
    19261 tatgcgatat aatacgaacg tattggataa tataaacaat aatattagtt tttcgtattt
    19321 gcagtaaatg tgaaaatatg ctatagtttc tgtgggaaaa gatcccaaaa ataatacaga
    19381 gtagaaaata aagcgttaag tgctaagagg atgggatgtt gcctcttgga cgaaggacgt
    19441 aatgttcgcg gttttatttt cgcattcgct gcatgatacg atgtagcagc tcttaaagga
    19501 gatgctaaaa atgaagaaac accggttaga cgcacgtatg attgctatta tgggcttatt
    19561 gattgcattg atggtcactt tgtcccgact ggtagcaatc gagaccccat ttattaaaat
    19621 cagtgtcaca tttattccac aagtgatcat gggcattctt tttggtcctt tttggtcagg
    19681 gataggcgca gttttagctg atttagtagg aatggccctc ttctcgaaat ctgcattctt
    19741 tattggattt acattgaatg catttattga aggagcaatc tacggattct ttttctatcg
    19801 aaaagagatc acttggaaaa atgccattct ggctacgctt agtgtcacgc tgatcatcaa
    19861 cttatttttg acaccattat ggcttgcgtt gatgtaccat gtgccattgt tcagctgggt
    19921 cgtttgggcg ccccgcctgt taaaaacagt aatatggtta ccgattcaat caattgccat
    19981 ttattacgta ggacgtagta ttccttacaa aaaaatttta agaagtttag cgatccacgc
    20041 taaataaaaa acaagcagtc ttcccatccc agaagactgc ttgtttttat tgtgctgtga
    20101 attgtgcttg atagagccgt cggtaataac catctttttg aagcagctca tcatgggtgc
    20161 ccatttcgac aatagctccc tgatccatca ctaatatctg gtccgcattt ttgattgtgg
    20221 acaggcgatg ggcaatcaca aaactggttt ttccttccat cattgctaag aaggcttgtt
    20281 ggattttttt ctctgtcaat gtatcgactg agctggtagc ttcatctaag atcaacatag
    20341 ggggattact gatcatcgtt cgagcaatcg tcaacagttg gcgttgtcca tctgatatct
    20401 ttaacccttg accgccaatc ttagtatcta atttttccgg caaacgttct acaaattcat
    20461 acatataaga ggcttttagg gcatcattga tttctgcgtc acttgcttcc ggattcccaa
    20521 aacgaagatt ttctcgcaat gtactgtcaa atagccaagt atcttgtaac accattccaa
    20581 aacttttacg taatgtatca cgttggatag agcggatgtc atggtcatcg actgtaattg
    20641 ttccttttgt tgtgtcataa aaacgcatca gcaaattaac aagtgtggat tttccggccc
    20701 ctgtttttcc tactatagca atggtttgac ctggataagc agtaaaattg aaatcttcga
    20761 tcaaacgctg cttggggtca taagaaaaag aaacatgatc aaaagagact tttcctttga
    20821 tatttttggg ttccaaggca taggcatctg gcaaatcagg cttttcttct ggctgatcga
    20881 tcaaatcaaa tgctcgttct agaccagaaa aagcggtttg cagttgtgtc gtgattccag
    20941 aaagttcgat aaatggttta gaaaactgac ttgagtagat cgtaaagctg gaaatcacac
    21001 caacagtgat tgacgaacca ctcttcaatg ccaataggcc gccaactaaa ccaatcgata
    21061 aataagcaag gtgatctaca aaacgagaag acgggtttgt caaggaagaa gaaaattgtg
    21121 cccgttgtcc tttttcatat agatcagcat ttagcagttc aaattgctgt tgactagctt
    21181 cttcttgctg aaaagctttc acgattttct ggttaccgat tcgttcggtc acaaagcccg
    21241 agatatcccc aataatcctt tgctgtctat cgaaatttgt ttgtgaagca cgagcaacga
    21301 tccaactcac aaggaaaata attggtgtag aacaaagaac gaccaatgtc agaagtggac
    21361 ttagacgcat cataaaaata aacgaaagaa tgatgattgc cactccagaa aataattgat
    21421 tgaaggccgc agaaattgca atggaaatat tgtccatatc atttgtaaat cgactgacga
    21481 tatttccgtg ggagttttga tcataataac gaagtggcaa tcgattcaga tgagcaaatg
    21541 catcttttct taattttgca acggataagt aagctaaccg attgcttaac acttggatga
    21601 gccattgact gactacgttg attaaaacga taccaccgaa tagaataagt aaatggaaca
    21661 gtcgattgaa gcggacctgt ccttctccaa tcatttgatc gatactttga ccaatttgta
    21721 acgtcatcac aactgttgca atcccattga tgattcctag tatcacagct agccaaatgt
    21781 cttttgcata ggcagtaagg taaggaatga atcggcggag cgtctgcaag gataattttt
    21841 ttactttcat aactattctt cctcctgtga tgcgacgatt tcctgatatt ctgctgattg
    21901 agcaagtaat tcttcatggg taccctgagc agcaatctta ccttgatcca tcactaagat
    21961 atgatgtgct tcttgaatag agcggacacg ttgggagata ataatcactg tactgccaag
    22021 ataagtctgt agcgccttac gcaaatccaa gtctgtttga taatccaacg cacttaaaga
    22081 gtcatctaaa atcagtaatg ctggcttggc aatcaaagct cttgcaatcg tcagtcgctg
    22141 tttttgtccg ccagagaaat ttttcccatt ttccatgact tttgtatcta aaccatttgg
    22201 aagctgacgg acaaattctt ctgcctgagc gattttcaga gcttcccaac attctttttc
    22261 tgtggcgtct ttcttacccc attgaaggtt ttcacgaata gtcccggtaa atagtacaga
    22321 agtttgggga acaagagcaa tttgctgacg gagatgatcc agctgccaag aacgaacatc
    22381 cattccgtcc attataactg taccggaact gacatcatag aaacgcggaa tcaattgtgt
    22441 caaagtcgtt ttcccgcttc cggttggacc aatgattcca aggactgtat ttcgcttcag
    22501 ctgaaatgta atattttgga gagaaagacc agaatcagga gtataacgga agtcaacatg
    22561 gtcaaaagcg ataattgctt cagaagaaaa atcgggagta gtactgacct cagcttcaag
    22621 aatcgaattt tctgtgtcta gcacctcttt cacccgattt cctgaagctt cggcacgtgt
    22681 gaagatcacg acgaggtttg aaacaacgat cagtgccaaa agcatttgat tcatataatt
    22741 gatcaaagca agaacttgtc cttgttgcaa gctaccaata tttactttga tcccgccaac
    22801 tgtcagcaaa cagatgatcc cgacattcat gatcaaggtt gtagcaggtg ataatagggc
    22861 agagatattg gaaacacgta aataattgtt cgctagatca tttgtgcttt tatcgaactt
    22921 ctctgtttct ttttttgtct gcgcaaatgc gcggatgaca cgaacaccgc taagattctg
    22981 actaacgtgt tcattgagct gatctagttt ttcttgcact ttttggtaga gaggaacggt
    23041 ttttttgatg ataaaaaata aaatgattga gaaaataggc aataatgcta agaaaaacag
    23101 acctacttcc cagtcgatca caaaagccat gaccactgac ccgatactta aaaacggtgc
    23161 tctgatcaat aaacgaatga ccattgctaa agctagctga agctgattga tgtcgtttgt
    23221 cattcgggtg atcaaggtat ctgttccaaa atgattcaac tcgttgtgag agaaagtatt
    23281 gatttttttg attagctgat tacgtaactc tgtaccaaat ccttgtgaag ctactgaagc
    23341 atagtattgg caaatgatag cacaaatcag accaatcaca gacatagcga ccatccataa
    23401 gcccatttca atgatttttc ctcggtcatt catttttagt ccattatcga tcaaggaagc
    23461 catcattaaa ggcaggacaa gttcgaagac agcttcaaga aatttgaaga acgggcccaa
    23521 aatgatttgc ttacgatagt cttttgcata acgtaataac tgaatcatat gattcctcct
    23581 attatttatt tgtccacaat tgaaaaaaca agtactacca cattgtagct taggaaattt
    23641 agaatgaaaa gagaacaagc cttttcataa atgaaagttt tattatgaag aagctttaga
    23701 aattgaatag actatttttt ttaaaaaaaa gaaaatgaga aaacatgcca gtctcttcat
    23761 tcataggaac gtctatttta cttaattttt ctataaatga attctgcata aaaaatatat
    23821 caagtaaatg tttatagatg aaactctatt tacttctttt ttaatttgtt cttgcaatct
    23881 tttttgctac gtaatttttg taaaaaagtg ggttgagaga aatctaattg attttcaaag
    23941 aaggagtatg aaaatgagaa aaatatttat tcgtttattg tgggtactat cttagaggaa
    24001 taaataatag tggagaaaac tatggtttgg cgcagattct atcaggtttg atggaacgaa
    24061 gacaacctcc cgacatcaag tcaaaagcta cttgagattt tgatctgaaa ataaaaaaag
    24121 aaaacaaggt aggaacatca atgtttctac cttgttttcg taatcaatgg gaaaaaacta
    24181 agagtggtgt acgtaatcaa taaaaaggat ggtgacaaca gtacctcttt actctctgaa
    24241 agcatcataa ctcgtttttc ctcattatgc caataaattg ttgttatacc acatataagg
    24301 atttgtaata gctaaaaaca gacaggaaag ttgaaatctg tgaatcttat tttgtatgga
    24361 aggatttata gaacgcaaaa atcaagataa agatgaataa aaatcctgtt tcggctatat
    24421 attgcgtatc tacgccaata aaacgagttt gttctgtcat agccatataa agcaaaggca
    24481 aaaatacaac tacagcgaga taagatccga tgatttctcg aaaagttttc caggaagtat
    24541 gtttcctgtt tttatattta tccgatttca ttgaatagtc atagcctcct tattctttca
    24601 tatgttgaaa ttccagtata aaaactggaa ggaactgtac gttttttaga ataaaaatta
    24661 taagggataa gtaggctgct gtctataata agatatattt ttcaattctt tattaaagat
    24721 tttattgaca aaatgaatcc gttttctatg atggaggagg ggtgaataag ttgttgaaga
    24781 aggaaatttt atgttactta gagaaccaga cagccttttt cgatttagaa catatgaacg
    24841 aggtctttac agcacaaagg ttagctgatc attttggggt aaaaagaaac acagtcagtc
    24901 attatttgaa ccagttaaat gatgagcaac tactagtcaa aatcaattct cgaccagtga
    24961 tttatttcca caaagaagct tttgaaaaac aattttttaa gttacgcacg aatttttatt
    25021 tttctatcga tgatctcaaa gaggaacagc cttttttcgc gcaaccaaaa gacttattct
    25081 cttttatgat cggatacgac gccagtttga aagaaagtat cgaacaaatc aaaacagctc
    25141 tttactatcc agatggcgga ttaccacttt tgattacagg cgaaagtggc acaggtaaaa
    25201 gttatttagt taatttggtc tatcagtatt gtctgcttca tgatctgcta gaagattctg
    25261 caccattcat cacttttaat tgtgcacaat atgcagataa tcctgaactt ttgactagca
    25321 atttgtttgg acatgttaag ggagcgtaca ctggtgcaga agaaaataaa aaaggggctt
    25381 ttgaagcagc agatggtggg atcttgtttt tagacgaggt acatcgctta acaccagaag
    25441 gtcaggaaaa actgttcacc tatcttgatc aaggtgtgat ttatcgtatg ggagaaccta
    25501 atttgtcacg ccggatcaaa acacgtctct tttttgctac gactgaagag attactagtc
    25561 atttcttaac aactttcatt cgaagaatac ctatccgaat cgaactacct gcacttaatc
    25621 agcgtagtcg taatgaacgg ctagaactga tttactcttt ttttctcgaa gaacaaagaa
    25681 aaatggggag ccctttgtca gtcagtggac cagctttgtc acttttaaca agtcagaaat
    25741 tatccggaaa cataggagag ctgaaaaata tcgtcaaagt ttcagcagca aaagcatatg
    25801 ctgaacagcg tgaacagcct gaaatccatg tcacgatcca tcatttgcaa aaagaactac
    25861 ttgcgcagcc tattactaaa aatacagcac agcaaggaat ctatattacg caagaccaga
    25921 ccttagagca attaatggag aagcaacagc ccgaacagca gcgaatcgtt aaaagttttg
    25981 agcaaatcct aattgatttc aagaaaaata actgtctgct atattcttgc gaaggaaaat
    26041 taaagcaaga agtgattcaa ttatttgatt ttttgctgtt tgagaccagt agacaagaaa
    26101 aacacgagct gctggtttat tggacacaat ctatccgaga gacctttcga caaatggaaa
    26161 ctgcctatca aatcaaattc gatggaaaca gtgtctatgc cttgagttac tatctctatc
    26221 agcgaagcac tatcaaatgg ttaccggaag aacatgatat tatccaacta atcaaagaat
    26281 tagaacaaca agtttctcag tcttatccat ctagttatca ctatgtccaa cgaattctgg
    26341 aattaagtaa gatcaaatta gatattgaag acacaagtat ggatcggatt ttactgacga
    26401 tctatctaaa aaaagcgaaa tggtcaaaag aaaaacgact gccaaaagcg atgattgctg
    26461 ctcacggtta tgcaactgct agcagtatgg caaatgtagt aaatcgttta ttacaagagg
    26521 atctatttga atcatttgat atgccactag atgtcacacc acagcagatt gcttcagaaa
    26581 tccttgatta ttgcgaaaac agcgatgttt caaatggatt gatcatatta gtagacatgg
    26641 gatctctgaa agaaatccat cagtttttta aaaaacagtt atccgtaccg cttttgattt
    26701 tgaataatgt gacgacacct ttagcaatca cagtagggga atgcctgcaa aaaaatgtat
    26761 cattagaaga gatagcagaa gagactgttc gacagatcca gccagaatgg cgactgctct
    26821 atccagagga aaacaaaccc aaagcactca ttactacttg cttcactgga atcggtacgg
    26881 cggtccactt aagtgaactg ctagaaaaaa gcttacctac ggcttgtcag ttgaaaatca
    26941 tcccatatga atatcagcaa ttaaaagata agaaaaacag tgacccatta ttttccatat
    27001 acgaagtcgt aggaatgatt ggcaccacag atcctgatat caccaatatc gactatcttt
    27061 cattagaaga cctcatctcg ggggaaaaga tgtctgtact agctgaatgg ttggacacta
    27121 ctatgaatgc ttcagagaag gaaatattca atcagcgcat cattcgtaat ttttcattgg
    27181 aaaaagtact ggattccgtg actattctag atacagagaa ggtgatggga gaaatcgatc
    27241 attttatgag agaattagag gtgcagttga atcgaagcat cagcaatccc aaaaaattag
    27301 cgttgtatgt ccatgtgagc tgtctcattg aacgattgat ccgacaaatg ccaatcgaaa
    27361 cctatcaagg attagagaaa tggaagcagt gtcaaaaaga agggttatct gctattaaat
    27421 ctgcgtttag tgtcattgaa gagcattata gtgtcatgat ccccaattct gagattgcct
    27481 atatctatga tattttgagt gaagatacag agtttctctc gatagaagaa gaattttgaa
    27541 cataagcaag ttgttgccac taattttggc atgcaacttg cttttttagt atgtgtaagt
    27601 gaaaagagga gatgaaaaag tggatagaga aattatctta gcttcccatg gaaaatttgc
    27661 ttcagggata ttagattcat tagagctgat ctatgggaaa aatcattcta ttactgtatt
    27721 cgattgctat actgatgaga attttgattt agcggaaaca gtaaggcagc tttttatgag
    27781 gtacaaagat aaagaaatca ttgttctgac ggatcttttt ggcggaagtg tcaacaacga
    27841 attcttacaa tatatcaatc gggatcatgt ctatctcgtt gccggattga atttgccact
    27901 attgattgag ctagtatctc ggttggacgc tgaagtagag acaactgttt tgatccagca
    27961 ggtgctaact gattcaaaaa aaatgatcca gttttgtaac gagcggctca atcagaaaat
    28021 agaagaagac gaattttagg aggaagaaaa atgattgtat tgacaagagt cgaccatcgg
    28081 ttattacacg gacaagtagc tttttcatgg acacaaacaa taggcgcaga ctgtattttg
    28141 attgctaatg atgatgtacc tacgaatgag atacgaaaga caacgatcaa attagccaag
    28201 ccacaaggag tcaaactagt gatcaaatca attgatgact cgattgccgc gttgaaaagc
    28261 ggggtgacag ataaatataa gttattcatc gtagtggaat cgatcgagga tgcatataag
    28321 ctggcagaag cgtatccaga aatcaaaacc atcaacttag gagggatcaa ggcaaaacct
    28381 ggtactcgca gcatcggaaa agcggtaaat attttaccag aagaggagga acgcttgaaa
    28441 cgattaattg acaaacaaat agaagtagaa atccgtcaag taccagcaga taaaaaagtg
    28501 gatgtaagag aagttttgta agaaaggaag aacctcaatg attgtacaag cagtcttatt
    28561 aggaattgtt gcatttgtcg cacaatcaga atatgcacta gggacatcgt tgctttctcg
    28621 tccgattgtg acggggctgt ttacaggaat cgtgttaggt gatgtaaaaa ctgggatcat
    28681 tatgggcgca actttagagt tagcatttat cggatcgttc tcagtaggtg cttcgattcc
    28741 acctgatgtt gtgaccggtg ggattttagg gacggctttt gctattacag ctggagccgg
    28801 tacagaaacc gcgcttttac taggtttgcc gattgctacg ttgacattga tattgaaaaa
    28861 tatttactta gggcttttga ttccaattat gaaccataaa gcagacaatt atgcagaaga
    28921 aggaaattat aaaggagtcg agcatatgca cttgcttgcc ggtatcggtc tttccttgat
    28981 gcttggtgtt gtggtaatgg tttcttatat ggtgggaagc aatacgatcg gaaatctatt
    29041 aaatatgatt cctgacttcg ttcaaaaggg gttgtcagta gctacagggt tgattccagc
    29101 tcttggtttt gcgatgcttg ctcgtttgct gatcaacaaa caagttgcac catatttttt
    29161 cttaggtttt gctatagctt cttacttaga gattcctgtg accggagtag ctatttttgg
    29221 tgcgatttta gcagttgtgg tagtcaatat tatgaatgtc cgtcaactac cacttcaaac
    29281 aactgcaggg gaggtagaag aagatgaaga attctgagat caaaaacagc aaaataacga
    29341 aaaaagagct aaatcacgta ttttggcgtt cttttcaaat ggagttttct tggaattatg
    29401 aacgtcagat gaatatggct tatgtttatg caatgattcc gattttgaaa aagttatatc
    29461 agtcgaaaga agaaatggca gcagctttga aacggcatct agagtttttt aacacgaccc
    29521 cacatatcgt tacactgatt ttaggaatca cggctgcaat ggaggaagaa aataaggatg
    29581 atcctgaatt tgatgtgact gcgatcgata gtatcaaaac atctttgatg ggacctcttg
    29641 cagggttagg agattctttc ttttggggaa ctttgcgatt gattgccaca ggtgtgggta
    29701 cctctttagc catgcaagga aatattttag gccctatctt gttcattttg attttcaata
    29761 ttccgcacat tctgtttcgc tatctagcaa caggttgggg atatcgctta ggaacgggtt
    29821 ttttgaaaaa gatccaggca aacggtatga tggaaagttt gacattaggc gcgtctatta
    29881 ttggactgat ggtcgttgga gcaatgactg ccacgatgat caccatcaat attcctttaa
    29941 aaatcggttc aggagaaaat gctgtgactg ttcaaagtat ttttgatgat atcgttccaa
    30001 atatcttatg tcttggagca tttggcatag tgttttatct attgaagaaa gaagtgaaac
    30061 cattaacgat cttgatcgga ctagctttct ttggaatttt tggttcgtgg atagggattt
    30121 tttaaaaaag gagcagagaa aatgtttacg atgcaagatt atatctatga agaaaaggaa
    30181 gtactaagta cgatcttgaa aaagaatgat ttttcgacaa gagaacatat gaaaaaaaca
    30241 gtgaatttac tgatcttagc aacgggttca tcttataacg cttgtttagc agcgaagcca
    30301 gcattggaat cttatggtga tcttactgtc gatattcaag aaccttttta ttttttcaat
    30361 tatggaaaac tttctccttc aatcgatact gtgattgctg tgtcacaaag cgggaaaagt
    30421 gcttctactg ttgaagcagt aaaaatgata caaaaacaag ggttacctgt tgttgctatc
    30481 acaaatgacg tgcaaagtcc acttgcttta gaagctgcac aaattattga tttaggtgcc
    30541 ggggtagaat cagtaggctt cgttacaaaa ggctattctg cgactgtttt acagttacta
    30601 ctcttaggga taggaattgg aataagtaaa aataaaatca gcaaaaaaat agaacaagac
    30661 tacatgcaac agttgcgcaa aataatcaac catttaccag cgattattca aaaaacggaa
    30721 gaattttttg atggatatca aagtttattt cgtttagcac agcgtttcgt caccattgga
    30781 tatggtccaa actggggaac agctaaagaa gcagagacga aattgactga aacaatccgc
    30841 gttccgtcac aaggatttga gttagaagct tatatgcacg gcccatacct ggaggcagat
    30901 gcttcgcatt tgctattctt tattgaaggg gaaagtgtaa ataaggaacg ttcgcaaaag
    30961 ttgcaaagat atatgagtcg gtacgttgga gagactctca ccattaccac aaaaaaagca
    31021 agaaacgaga aaacacttgg attagcaata gaatgtgatg aatatctgtc tgtattagcg
    31081 cttgtcgttc cgtttcaact attcgcttat aaaaccgcag tagctaaagg tattgacttg
    31141 aacaaaaaga tttttgaaga ctttgataca gtcttgaaaa gtaaattata agaggtggaa
    31201 atcatgctga aattcaatga agaagaacaa atcaaagcaa taaaaggcgc actagcttta
    31261 cgtccgcaag tagaagaaat catcgataaa ctttatgcgg aaaaatttga cgctgtctat
    31321 tatctaggaa tcggtggaac gtatgcttcc tcgatgcaag ctgtcactta tatgaatggg
    31381 aaaagcaact tgcctgtctt tgtacagcat gctgcagaat attacactac tggaaacaaa
    31441 agattaacaa aagattctat cgttattttg tcctctgtta ccggtacaac tcaagaagta
    31501 gtgaaagcag tagaacaaat caagaaagta ggagcgacac tgattggatt tatcgataaa
    31561 gcgaacagta agttgtctca gctatgcgat tttgtggtca cttatccagc tcctggaaca
    31621 gaacaaatca aattttttat ggcagcagat cgattgatgt atttgaatgg agaattcgaa
    31681 gcttattcag aatactatga acagctcgaa cgttatttac caacagggtt agtggaagca
    31741 gagaaaaaag cagatgcatt tggcttatca tttgcagaaa aacatcgacg tgatagtatg
    31801 cattatttta ttggagcagg gaatcaatgg ggagctgttt attcatatgc catgtgttac
    31861 tgggaagaac aaagctggct tccatcgaaa tctatccatg ctgccgagtt tcttcacggg
    31921 acgttagaga tcgtagaaga aacaacccca gtcacattat ttttaggcga agatgaacag
    31981 agagtgttat ctgaacgtgt ggctaaactt ttgccaaaaa tttgcagcaa ttatacattg
    32041 atagacacaa aagactatcc agtagaaggt atcagtgaaa aatatcgcgg acgtgttttg
    32101 tctttcttat tgatgcatgt agtgacacaa cgcatcgatg ctcatgtgga gcagttgaac
    32161 tgccatccat tagagatacg ccgctactat cgtcagtttg attattagga tagactggat
    32221 aaaaagaata taaaaaataa agagagcagc gataactgct ccctttattt ttttaaaata
    32281 ttggcatcaa ttacgttata aaacacattt tttgcattat ctacagttca acttataatc
    32341 tgtttaatgg gacatgtggg tgccaaccat tttttgttat gcaatagtac tatttagttg
    32401 ttgcatggat ccgtagtaaa agtccaagta caacgagttg cgccagttta catagcgttt
    32461 tgtatccaga atgttgacta aaacaaaagt tcctatgtca accgtcaaca gagacaatct
    32521 gtccgttgca ggacctgaca gatttagaaa tgttcaatct gtctcttatg tattttaaat
    32581 caatactcac taggagaagt ttcctaacct cctaatagta atgctggtag taacattgtc
    32641 aaaactgctt cctcttagga acaagcaaag cataacgagt gtaaaaataa aatgtagact
    32701 attgtaacat atcattgatt atttcaagta aaaacgataa aagaagtaaa caaacactta
    32761 aaaacaatgg aaattagtcc caactttaag aaatgtatac tataatggaa attatcaatt
    32821 atttatttgg aggaatatcc atgaaacaaa aaatcgcagt tcttggtcct ggatcttggg
    32881 gcactgcttt agcacaaaca ttggcagaaa acgggcatga tgtccgtatt tggggaaatg
    32941 tacctgaaca gattgatgaa atcaataagt atcatacaaa tcagcatttt ttacctgatt
    33001 tgacgatccc agaatcgatt atcggatata aagaattggc agaagcagtg gataacgcag
    33061 atgctatttt atttgttgtt ccaacaaaag cgattcgttc agtcgcacag gaacttattg
    33121 gtaaaatgaa tactaagcca atcattatac atgcaagtaa aggactagaa caagatacgc
    33181 ataaacgaat ctcagaagtt ttggctgaag aaattccaga agaaaaaaga caggcaattg
    33241 ttgtattatc tggtcctagc catgctgagg aagtggcagt acatgatatc acaacaatta
    33301 cagctgcaag tattgatcaa aaagcagcag cctatgtaca aaaactgttc atgaatgatt
    33361 atttcaggat ttatacaaat aatgatgtga ttggcgtaga aactggtgca gcactgaaaa
    33421 atatcattgc aattggtgcc ggcgctatcc atggattagg attcggagat gatgcaaaag
    33481 cagcaatcat gactcgagga ttggcagaaa tcagccgtct tggtgtcgcg atgggtgcca
    33541 atcctctgac atttatcggt ttgagtggtg tgggggactt gatcgttact tgtacaagtg
    33601 ttcattctcg caattggcgt gccggtaact tgttaggaca gggacataag ctggaagaag
    33661 ttctagaaaa catgggaatg gtcgttgagg gtgtggcaac gacaaaagca gcagtagagc
    33721 tagctcaaca gctaggtgtt gagatgccaa ttactcaaac aatctataat gttttgtata
    33781 atggagaaga tatcaaaaaa gcagcaaaag aaatcatgtt acgtgacgga aaaatggaga
    33841 atgaattttc tcttcgttaa atagatgatc aatagttaat cgt
//
LOCUS       DAYYEF010000030        33266 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000030 DAYYEF010000000
VERSION     DAYYEF010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 33266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.030"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(42..230)
                     /gene="rpmB"
                     /locus_tag="ACHA1B_001574"
     CDS             complement(42..230)
                     /gene="rpmB"
                     /locus_tag="ACHA1B_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HFM8702342.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            500..862
                     /locus_tag="ACHA1B_001575"
     CDS             500..862
                     /locus_tag="ACHA1B_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFM8702343.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            914..2596
                     /locus_tag="ACHA1B_001576"
     CDS             914..2596
                     /locus_tag="ACHA1B_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HFM8702344.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2713..4749
                     /gene="recG"
                     /locus_tag="ACHA1B_001577"
     CDS             2713..4749
                     /gene="recG"
                     /locus_tag="ACHA1B_001577"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HFM8702345.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVDLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4798..5799
                     /gene="plsX"
                     /locus_tag="ACHA1B_001578"
     CDS             4798..5799
                     /gene="plsX"
                     /locus_tag="ACHA1B_001578"
                     /EC_number="2.3.1.274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HFM8702346.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5921..6163
                     /gene="acpP"
                     /locus_tag="ACHA1B_001579"
     CDS             5921..6163
                     /gene="acpP"
                     /locus_tag="ACHA1B_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000036 - acyl carrier activity [Evidence
                     IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HFM8702347.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6431..7435
                     /locus_tag="ACHA1B_001580"
     CDS             6431..7435
                     /locus_tag="ACHA1B_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702348.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7436..8380
                     /locus_tag="ACHA1B_001581"
     CDS             7436..8380
                     /locus_tag="ACHA1B_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702349.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8380..9342
                     /gene="opp4B"
                     /locus_tag="ACHA1B_001582"
     CDS             8380..9342
                     /gene="opp4B"
                     /locus_tag="ACHA1B_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease"
                     /protein_id="HFM8702350.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9369..10283
                     /locus_tag="ACHA1B_001583"
     CDS             9369..10283
                     /locus_tag="ACHA1B_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702351.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10309..12090
                     /locus_tag="ACHA1B_001584"
     CDS             10309..12090
                     /locus_tag="ACHA1B_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM8702352.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12438..13124
                     /gene="rnc"
                     /locus_tag="ACHA1B_001585"
     CDS             12438..13124
                     /gene="rnc"
                     /locus_tag="ACHA1B_001585"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004525 - ribonuclease III activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HFM8702353.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13144..16725
                     /gene="smc"
                     /locus_tag="ACHA1B_001586"
     CDS             13144..16725
                     /gene="smc"
                     /locus_tag="ACHA1B_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007059 - chromosome segregation [Evidence
                     IEA];
                     GO_process: GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HFM8702354.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16734..17543
                     /locus_tag="ACHA1B_001587"
     CDS             16734..17543
                     /locus_tag="ACHA1B_001587"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM8702355.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17554..18552
                     /gene="ftsY"
                     /locus_tag="ACHA1B_001588"
     CDS             17554..18552
                     /gene="ftsY"
                     /locus_tag="ACHA1B_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005047 - signal recognition particle
                     binding [Evidence IEA];
                     GO_process: GO:0006614 - SRP-dependent cotranslational
                     protein targeting to membrane [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HFM8702356.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18739..21006
                     /gene="gshAB"
                     /locus_tag="ACHA1B_001589"
     CDS             18739..21006
                     /gene="gshAB"
                     /locus_tag="ACHA1B_001589"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004357 - glutamate-cysteine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HFM8702357.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21095..21547)
                     /locus_tag="ACHA1B_001590"
     CDS             complement(21095..21547)
                     /locus_tag="ACHA1B_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HFM8702358.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21697..22647
                     /locus_tag="ACHA1B_001591"
     CDS             21697..22647
                     /locus_tag="ACHA1B_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFM8702359.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22640..23599
                     /locus_tag="ACHA1B_001592"
     CDS             22640..23599
                     /locus_tag="ACHA1B_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HFM8702360.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23596..24351
                     /locus_tag="ACHA1B_001593"
     CDS             23596..24351
                     /locus_tag="ACHA1B_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702361.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24374..25327
                     /locus_tag="ACHA1B_001594"
     CDS             24374..25327
                     /locus_tag="ACHA1B_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM8702362.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25971..26267)
                     /locus_tag="ACHA1B_001595"
     CDS             complement(25971..26267)
                     /locus_tag="ACHA1B_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HFM8702363.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26622..26978
                     /locus_tag="ACHA1B_001596"
     CDS             26622..26978
                     /locus_tag="ACHA1B_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFM8702364.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26988..27887
                     /locus_tag="ACHA1B_001597"
     CDS             26988..27887
                     /locus_tag="ACHA1B_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFM8702365.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28407..29135
                     /locus_tag="ACHA1B_001598"
     CDS             28407..29135
                     /locus_tag="ACHA1B_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFM8702366.1"
                     /translation="MKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEAG
                     DEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYAA
                     ADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAVS
                     LVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSVP
                     GKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29280..31307
                     /locus_tag="ACHA1B_001599"
     CDS             29280..31307
                     /locus_tag="ACHA1B_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HFM8702367.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31415..32512
                     /locus_tag="ACHA1B_001600"
     CDS             31415..32512
                     /locus_tag="ACHA1B_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFM8702368.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            32819..>33266
                     /locus_tag="ACHA1B_001601"
     CDS             32819..>33266
                     /locus_tag="ACHA1B_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702369.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT        11141 a         5762 c         7123 g         9240 t
ORIGIN      
        1 aaaaaaccgt tcactatctg aacggtccaa gtatcattca attaaacgcg ttcaactttt
       61 cctgatttca aagcacgagt tgacacccaa acttttttag gttttccgtc gaccataacg
      121 cgaacttttt gtaagttagg tttaacagta cgttttgttg agttcatagc gtgtgaacgg
      181 ttgtttccac tttttgtctt gcgacctgta aagtaacaaa cttttgccat ggtaatttcc
      241 tcctttgcct tgatttggag caatagaata attcagctca taccagacta acatatcata
      301 tagaatggaa atttgcaagt acattttcat agatacaatt gacaattgag aagaataatt
      361 gtaaattaaa caaggttata cctgaaattt tgcaaggttt ttgagtactt tgggtaactg
      421 ccttttattt caagttgcgc tatgataaaa tatgatagaa gaaaaatggg agttttttac
      481 ccgttaagga ggctcattca tggctgtaaa aattcaaacg tcagctggaa ccattgaaat
      541 taccaatgat gtaattgcaa cagttgttgg tggcgccgcg acagatgtgt tcggtgttgt
      601 aggaatggcc agcaaaaatc aaattaaaga taatattact gagattttgc gtaaagaaaa
      661 ttactcaaga ggagtagttg tccgccaaga agataatggt attgctgtag atgtttatac
      721 gattatcagc tatggtacga aaatctctga agtttcccgc aacgtccaag aaaaagtgaa
      781 atacaatcta gaggcattat taggcgtaac tgccaattca gttaatgtct ttgtacaagg
      841 tgttcgtgta ctgccagact aggcaggaga ctggctggta actcagcagt cgatctgaag
      901 gaggattatc taggtgagtg taacagaaat aagtgcaagc cagttccagg aaatggtcca
      961 ggcaggtgcg aatcgtctgc aagtaaatgc agaatacgtc aattcattaa atgtattccc
     1021 tgtgccagat ggcgatacgg gaacaaatat gaatctatct atgactagtg gagctaaggc
     1081 agtagtagat tcaacctcag aaaaagtagg agaattagca gcaatgcttt caaaaggatt
     1141 gctgatgggt gcgcgcggaa attccggcgt tattttgtct caattgtttc gtggattttc
     1201 taagcaaatt ccagatgttg tctcattaaa tgcttccgat cttgctgcag ccttcactca
     1261 tggagttgaa actgcgtata aagcagtaat gaaaccagta gaaggaacga ttttgacagt
     1321 agctagagaa gcagcgaaag ctggagaaaa gaaagcaaaa agtactgatg atgtcgttga
     1381 agtaatgaca gctgttgtaa aaggggcaaa gcgtgcttta gctaaaactc cagacttgct
     1441 tccagtccta aaagaagtcg gtgtcgtaga cagtggaggg caaggactgc tgtttgttta
     1501 tgagggcttt ttaagtgcat tgaatggaga attccaagcg gatgaaacat atgaaccttc
     1561 tccagcagaa atggatgata tggtcaatgc agaacatcat cgcagtgtcc aaggtcaaat
     1621 ggcgacagaa gatatccatt ttggttactg tacagaaatc atggtaaaaa tcggagaagg
     1681 acctacagtc gatagtacat tcgattacga agaattccgt aactatttag atggtatagg
     1741 agattcttta cttgtggtca atgatgacga gatcatcaaa gtccacgtgc atacagaaaa
     1801 cccaggagaa gtcttgaatt atggacaaaa attcggttca ttagtcaaaa tcaaagtcga
     1861 caacatgcgc ttgcagcatg agacgatttt ggaacacgat gaagaagtga acgagtttgc
     1921 gaaaaaagaa acaccacgta tcccgtatgg tatcgtagcg atcgctgctg gtaaaggcgt
     1981 ccaagagctg tttgaaagtt taggcgctaa ttatgttatc agtggtgggc aaacaatgaa
     2041 tccaagtacg gaagacattg ttaaagcgat tcaagaagta aacgcagata aagtgattgt
     2101 cttgccaaac aataagaaca tcttcatggc agctgatcaa gcagcagaag tagcagatat
     2161 cccagtagca gttgttcctt caagaacgat ttcccaagga ttgacagcta tgctttcatt
     2221 caatgatcaa gcttctttag aagaaaacaa agaaacgatg acagaaatgt tgtctagcgt
     2281 tgtgagcggt caagtcactc acgcgatcag agatacctca attgacggtg tagagatcaa
     2341 agaaggagac tttttgggca tgatcgatgg aaaaatcctg atctctaacc cagatatcac
     2401 agcaacagcg ttaagtacac tagaacaaat gatcaatgag gacacagaga tcgtaacgat
     2461 cttggcaggt gatgaaggaa cagttgaaca agcaaatgaa tttgctgaga aactaacaga
     2521 aaaacatcct gatttggaaa tcgagatcca ccaaggagat cagcctgtct atccttatct
     2581 attttctgct gaataatttc tgtgtcagaa tatctttcta acacagtatt cattcataaa
     2641 aggccttcgg ttagtgatca ggtatgatcg ctgaccaagt cctttttttg ttaagggagg
     2701 gaggaaaaat ttatgcgttc tttagatgat ccaatcacta tgctggcagg agtcggagaa
     2761 aaaagagcag ctagtcttgc cagcttgggc atccaaacga ttgaagactt actgacttat
     2821 tatcctttcc gctacgaaga tattcaggaa agaaatctaa acgagatcca agatcaagaa
     2881 aaggttactt tgaaaggaat cgtagtctcg cctcctgtga tgaatcgatt tggttataaa
     2941 aaaagccgat tgcaatttcg tatgatgcaa gaacatgatg tgttcaacgt ttcttttttt
     3001 aatcaacctt atctaaaaga aaaagtcatt ttatcggagg aaatcgccgt atacggtaaa
     3061 tgggatgcaa agcgtaaagc attgaacggg atgaagattt taggttctca aacaatggat
     3121 gacttttcgc cgatatatca cgtcaacaaa tcaattcgtc aaacgacatt agttgatcta
     3181 atcaaaaaag ggtttcaaga atacggcaca ttgattgaag aaaatctgcc aaacaacctt
     3241 gtggagaaat atcgactgct tgaccgagct tctgctgtaa gaagtatgca ttttccaaaa
     3301 gaccacgaag aaaaccatca agccaaacga cgtgtcgttt ttgaagagtt ctttttattt
     3361 caaatgcgtc ttcaaggatt gaaaaaagca gaaaaagcag aaacgaatgg tttggagatc
     3421 ctttatgatg tccaaaaatt gaaagaattt actcaaaagc taccttttga actgacaaat
     3481 gcacaaaaac gtgtaacgaa tgaaatctgt cgggatcttc gcagtccgca gcatatgcag
     3541 cgacttttgc agggagatgt aggtagcgga aaaacagtgg ttgccgcgat tgcgttatac
     3601 gctaccgtta cagcaggttt ccaaggtgcg ttgatggtgc ctacagaaat cttggcacaa
     3661 caacatatgg aaagcttgca acagctgttt gatcccaatg aagtaaccat cgcattgctt
     3721 acggggtcaa cgaaagcaaa agaacgtcgt gagctccttg aaaaactaga gcaaggggaa
     3781 attaacatcg tgatcggcac acatgcattg atccaagatg gagtcgaatt tcagaattta
     3841 ggtctagtta ttacggatga gcagcaccgt tttggcgtga accagcggaa agtacttcgt
     3901 gaaaaaggct ggcgaccaga tgtcttattt atgacagcga ctccgattcc tagaacatta
     3961 gctattacag catatggtga gatggatgta tctatcattg atgaacttcc agctggacgt
     4021 atcccgatcg aaacacgctg ggtaagaaca cctcaattgg acagtgtact ggattggacg
     4081 aaaaaagaac tggcaagagg acatcaaatg tatgtcatct gtccgctgat tgaagaatca
     4141 gaagcattag atgtaaaaaa tgcagtggaa atctatgaaa aacttcgtga actatttgca
     4201 ccaaaatatg aagttgactt gttacatggt aaaatgaaga atcaggaaaa agaagtaatc
     4261 atggaagcct tcaaagacaa ccagatgcag atattagttt cgactactgt aattgaagta
     4321 ggggtaaacg tgccgaacgc gaccgtcatg ctgatcatgg atgcggatcg atttggattg
     4381 gcacagctgc atcaacttcg tggacgtgtt ggacgcggaa gtgatgcttc ctactgtatc
     4441 ttagttgcta atcctaaaaa tgaactaggt gtggaacgga tgaaaatcat gacagagacc
     4501 accaatggtt ttgtactaag cgaaaaagat ctggaattac gtggtcctgg tgaagtattt
     4561 ggcttccgtc aatctggtct gcctcaattt gcgattgctg acttggtgac ggatggaaat
     4621 gttttggagg tagccagaga agaggctgca gccctttggc agataaagga ttggcagatg
     4681 cttcctgagt atcagccttt agcgcaaagc ctccaaatag aaaatcagga taatcgttat
     4741 ttcgattagc agactgtgct atactttata ctgatgacgg aaaaaggagt ggaaacaatg
     4801 aaaattgccg tagatgcaat gggcggagat cacgcacctc aagcaattgt agaaggcgtg
     4861 gctttagcgc agcaagattt tccagaagta gaattcttac tttacggaaa agaagcagaa
     4921 atcaagaaat acttaacaaa tgaaaaaaac atcacgatta tccatacaga cgaaaaaatc
     4981 aatagtgatg atgagccagt aaaagcaatt cgacgaaaaa agactgcatc aatggtcctt
     5041 gctgcacaag cagtgaaaaa cggtgaagca gatgctgtat tttcagcagg gaatacaggc
     5101 gcgctactag cagcagggtt gttcatcgta ggacgtatca aaaatatcga acgccctggc
     5161 ttgatgtcta ccttgccagt agtagggaaa gaaggtgccg gtttcgatat gctggatctt
     5221 ggcgctaacg cagaaaacaa accagaacat ttgttgcaat acggtatttt aggttctttt
     5281 tatgcacgta aagtccgagg tatcggacgt cctcgtgtcg cactcttaaa caacggaaca
     5341 gaagcaacaa aaggtagtga agtgacgaaa aaagcctatg aactccttca gaatgaaaca
     5401 agcttgaatt ttattggaaa cgtagaagct cgtgagctac tcaatggtgt ggctgatgta
     5461 gtggtcacag atggatttac aggcaacgct gttttgaaat ctattgaagg aacagcaatg
     5521 aatatgatga atctattaaa atctgctatt ctaaatgaag ggatcaaagg aaaaatgggc
     5581 gctatgcttt taaaagacgg cttacgttct ttgaaagcag aaatggatta ttccaaacat
     5641 ggcggtgccg ttttgtttgg cttgaaagca ccagtcatta aaactcatgg agcaacaggc
     5701 cccgatgctg ttcgctatac gatccgccaa atccacacaa tgcttgagac agatgtagtt
     5761 ggacaattag tcgaacaatt tgaaaaaagc gaagaatagt atttggatat ctgaagcaat
     5821 ccgttccatt gaaaaaaagg tggacattcc tgaaaaatgc cagtaaaatt agccatggtg
     5881 taggtaattg acaagtgtat gattcttgga ggtgaaaaag ttgactcgcg aagaagtatt
     5941 taacaaagta gcgaaaatta tttcaaatca ttttgagata gataccgata aagtgacgga
     6001 tgaattgaac atcaaagatg atttaaaagc tgattcaatt agtattatgg aattcgtttt
     6061 agagcttgaa gatgaattcg gtacggaaat ttcagatgaa gacgctgaac aaattgaaac
     6121 agtcggtggc gcagtagatt atatcagcag ccatcttaaa taatttcaaa taaaagcaaa
     6181 gaaggataaa aagctgcata cagcttttta tccttctttt tttaatcttt ttgacacgta
     6241 aaagtcattt ttctgataat tctggcgata aacagaaatt atgttgcaaa gtaaagcgat
     6301 tttctatata attattaata attcattaca caaagataag aataaccttt gttataaaac
     6361 gctttattct gtgtaatgtc cttttttatt aagaaaaact tccatttagg aagcagagag
     6421 gggtattcga ttgtccgata accaattatt agaagttcag aacctacata caggattccg
     6481 actcaaagat gactattacg atgcagtaga tgacgtttca tttactttag acaaaaacga
     6541 gattttagca atcgttgggg aatctgggtg cgggaaaagt accttggcta ctacgattat
     6601 gggattactt gatcctaata acacaaaaat tacaggtgag attttatata acgatctgaa
     6661 tttaatcgac ctgaacgaaa cgctctataa taaaatccgc ggaaatgata tcggaatgat
     6721 tttccaagat ccgttgtctg cattaaatcc tctcatgaga atcgaagacc agatcaaaga
     6781 aggactttcc tatcacacaa agatgaatgc agaacagcgt caagctcgtg cactagaatt
     6841 gctagaacaa gtagggattc ctaatcctgc gagagttgga cgccaatatc cccatgaact
     6901 atcaggcggt atgagacaac gtgtcatcat cgcaatcgca atcgcctgca aacctccaat
     6961 cgtcattgca gatgaaccga cgacagccct agatgtaacc atccaagcac agattcttga
     7021 tttactgaaa gaccttcagg aagaaacaaa aacagggatc atcttgatca ctcatgactt
     7081 aggagtcgta gcagaaatgg ctgatcgagt ggcagtgatg tatggcggac agttcgttga
     7141 agtagcaggt gtaaaagaac tgtttgatca tcctaagcat ccttatacac gctctttact
     7201 gaactctata ccacaagaag gaaatcatga tgcagaactc catgtgatcg aaggtgtcgt
     7261 tccttctctg aaaaacatgc ctcgtaaagg ttgtcggttt gcaccacgta ttccatggat
     7321 accagcaagc gatcatgaag aagagcctat ccttcatgaa gtcgcaccga accacttggt
     7381 acgttgctcc tgctataagc atttccactt tagagacgaa aaaggagagg tgtagatgac
     7441 agaattaatc acaatcaaag acctgaaagt tcattaccct attcgcagtg gattcttcaa
     7501 tcgagtaacg gatcatgtat atgctgtaga tggtgtggat tttattatcg aaaaaggaaa
     7561 gacatatggt ttagtgggag agtctggctc tggaaaatct actacgggaa aagccgttgt
     7621 gggattagaa aaggtaacag ccggacaaat catgtatgaa ggaaaagatg taacgaagcg
     7681 aagcaaccgc aaaaaaatgg gttataacaa ggatgtgcag atgatcttcc aagattcaat
     7741 gtccagtttg aatcctaaaa agcgagtgtt ggatatcatt gctgaaccca tccgaaattt
     7801 tgaacggtta agcgatcaag aagaaaagaa aaaggtaaaa ggactgctag atatcgttgg
     7861 gatgccggaa gatgcgctat ataaatatcc tcatgaattt tcaggcggac aacgtcaacg
     7921 tctaggagta gcccgtgctg ttgctaccaa tccaaaactg atcgtagccg atgaacctgt
     7981 atctgctctg gatctatctg ttcaagcgca agtattgaat ttcatgaaac gaatccagca
     8041 agaatacggc ctcagctatt tattcatttc acatgattta ggtgtagtaa aacacatgtg
     8101 cgacaatatc gcaattatgt acaaaggtcg atttgtagaa atcggtacaa gagaagacat
     8161 ttataatgac ccgcgacata tctatacgaa acgtctgctt tcagctattc cgcaaatcga
     8221 tgtagaaaat agggaaagcc acaaagaaaa tcgacgaaga gtagaacaag agtatatcca
     8281 aaaccaaaaa gaatactatg atgcgactgg tcgagtctac gatttgcgta cgatcacaac
     8341 tacacacaaa gtggcgttga aagatggagg tgcaagctaa tgtggaaaac gattctgcga
     8401 cgtgttttat tgatgatccc gcaagttatt attttaagtg ttctgatctt cttattagcc
     8461 caagcgatgc cgggggatcc atttaccggt ttgatcaatc caaatcagga tccggcagtg
     8521 atcgaacaga tgcgacaagc agctggcttg aatgacccat ggtatgtcca gtacttccgt
     8581 tggatcggaa atgctttgca aggcgatttt ggtcaaagtt tcttatacaa acgctctgtt
     8641 gctgacttga tcggcgaacg gatcatcaac actttatatc tatcgatctt gacagttgtc
     8701 cttacttatt tgattgctgt gcctctgggg atgcttgctg gccggtatca aaattcaatc
     8761 ttggataaga ttgtcgtaat ctacaacttc tttagttttg ctgttccttt atttatcttc
     8821 ggcttgatca tgctatttgt ttttggttat cgtttaggct ggttcccaac aagtggatca
     8881 caaacactag gtttgcaagg tggatttatc actcaatgga tagaccgttt gaaatatatt
     8941 ctgttaccat caattaccca agcatttttg gcgactgccg tcacaatcca atatctgcga
     9001 agtgaagtaa tcgattcgaa atcgctcgat tttgtcagaa cagcccgttc caaaggggta
     9061 ccgacgaata aagtattcag tcgacatatt ttccgaaatg cagcgttgcc gatggcttct
     9121 caaatggggt atgaaatcac ttcgttgatt gctggttctg tagttatcga aaagattttt
     9181 ggttatccgg gagtcggaaa actatttatt gattccatcg gccaacggga ctataccgtg
     9241 atcacatcct tagtattgat tttaggaatc gcgacgctag tggggacatt actttcagat
     9301 atcatcatga gtatcgttga cccgcgtatt cggattcaat aaaaccaatc agaaaggaga
     9361 atggatcgat gagtgaaaaa aacaatacag cagttcaaga aagtattcct cctatgggga
     9421 tacgaatgat tgctcgagaa tttaaaaaag ataaaattgc tattttttca ttaggtttgc
     9481 tagtggtttt attattagtg atctttatcg gtgcgatgct gaccgatcaa gacaaagtga
     9541 tgtatgttag tatcttcgac aaatacgctg caccaggaac agtttcgaca caaggacaaa
     9601 agttcattct gggagcagat gaaggcggac gtgatgtatt aggacaattg atcataggtg
     9661 ctagaaactc tgttacgatc ggatttgcga tcacgatcct tacttcgatc atcggggttg
     9721 gattagggat catctctggc tactacggag ggatcattga caacatcttg atgcggatcg
     9781 ttgattttat catgattcta ccgatcatgc tgatcattat cgtcttcgta tcgattattt
     9841 ccagatacaa tgtctggtcc tttatattca tcatgagtgc attttattgg gtagctaaag
     9901 cccgattatt ccgaagcaag acattatctg aagcaagaag agattatgtc agtgcctcaa
     9961 aaacaatggg aaccaatgat tttaaaatca tgttccgcga aatcatgccg aatctaagtt
    10021 cattaatcat tactaatttg acgatgaact ttgcggcaaa catcggtatc gagacaactt
    10081 tgactttctt aggtttcggc ttgccggcaa atgtacctag tttaggtaca ttgatcggtt
    10141 atgcaagtaa cggagaagtc ttagtgaatc ggcaatggat ctggttaccc gcatcaatcc
    10201 ttattttagt tttgatgttg agtatcaatt atgttggaca agcattcaag cgttctgcag
    10261 atgcgcgcca acggttaggc tagtatagaa gcgaaggggg aaataggaat gaagaaaacg
    10321 atttttggat ttgcagcgct gatgtctgct gtcgttcttg cagcatgcgg gggcggaggt
    10381 acagatacct ctggaaacaa ctctggaggc aacggcaata acaaagagga attaactttt
    10441 ccaattgcaa caaaaaataa tgatgatgca atcgaagacg gcgaattaga agctgcggtc
    10501 gcaacggaca gtcagtttaa aggattgttc cagtgggagt tttaccaaga ttcatatgat
    10561 gcagctttta tggctccttc tcatgaaccg ctatttgcaa acgatgacga tttcagaatc
    10621 acagacgacg gagctgcaac gcttgatcta gatgaagata cgaaaaaagc gacaatcaaa
    10681 gtaaaagaca acgtcaaatg gtcagatggt gaagatgtaa cggcggacga tgtgattttc
    10741 ccttacgaaa tcattgggaa taaagattac actggtatcc gttatgacga cactttccgt
    10801 aacatcgtag gtatggaaga atatcatgat ggaagtgccg acacaatctc cggaatcaaa
    10861 aaaatagacg acaaaacagt tgaaatcgaa tataaagaag taaacccaag catgcttcaa
    10921 tcgggtggtg gtatctggtc atatgcagca ccaaaacata cgttagaagg tgtagcaatc
    10981 aaagatatgg aatcaagcga tcaagtacgt aaaaatccag tgacttttgg cccttattac
    11041 atgagtaata tcgttgcagg agaatcagta gaatacttgc caaacgagca ctactggaat
    11101 ggtacgccta aattgaaaaa gatcacgatg aaatctgtac cgatggcaag tgcaactgaa
    11161 gcattgaact ctaaattata tgatatgatt ttccaaatgc caacagatac ttacgatacc
    11221 tataaagaaa ttgctggcta tacaaactta ggccgtgaac aaacttctta tacttatcta
    11281 ggattcaagt taggtaaatg gaatgcagat acaaagagtg tggaatacaa tccagattca
    11341 aaaatggctg ataaatcatt acgtcaagca atgggctatg cattagataa taatgcagta
    11401 ggtgaacgtt tctatgcagg tttgagaagc aatgcgactt cattgattcc tccagtattc
    11461 cagtcatacc atgatgatga gatgaaagga ttcacacaag atctagacaa agcgaaaaaa
    11521 ctattagatg atgctggcta caaagatgtg gatgacgatg gtttaagaga agacaaagat
    11581 ggaaataaac taacaatcaa ctttgcttcg atgtccggtg gggaaacagc gcaaccattg
    11641 gcagattact atatccaaca atggaaagaa attggtttgg atgtccaata cacaacaggt
    11701 cgtctgatcg aattcaattc tttctatgat aaattagaaa acgatgatcc tgaaattgat
    11761 gtttaccaag ctgcttggaa tacaggaact gatccaaatc caagtggact atggggacca
    11821 aatgctgcgt tcaactacac tcgttatgaa tcagaagaaa atacaaaatt gatcaacgat
    11881 atcagttcaa gcaaagcatt tgatgaagag taccaaaaag aagcatatca aaaatggcaa
    11941 caatatgcat ttgaagaagc atttgcgatt ccaacgttgt tccgtaatga agtattgcca
    12001 gtcaacgacc gtgtcaaaga ctgggattgg tcttatgatg taccaaaccc atgggcaaat
    12061 gtttctgtta cagcagattc acgttcataa tcactaaaaa tgaccgaaaa agggcgatgt
    12121 cctttttcgg ttttttgata tttttctgtt tatttctcta atattcaggt caaggcgctg
    12181 atttcatgac ttctccaata aacggtgttc aaagtccagt ttctcggtat taagtcaaat
    12241 ttatgcaaaa atatggaaag ccattttcac aaaatttttt cttcatactc gaaactaaac
    12301 gaatttttca caacttctcg tcaatcacta ggattattaa agctttactt accttttgac
    12361 cgaaccattt caaatttgac aaaaaaccag tataataagg aagtatcgaa aaaatatcca
    12421 taaaaggaat gtggaaaatg gacaaccagc tgacaaaaga actaaaagaa aactataaca
    12481 tcgtttttca cgatctaaat ttgcttgaac aagcttttac ccattcatcc tatgtgaatg
    12541 agcatcgcaa tctgcaatta tcggataatg agcgacttga atttttagga gatgccgttt
    12601 tagaactgat ggtttctcag tatttattcc gtttatatcc tcatttgcca gaaggaaaat
    12661 tgacaaaaac acgagctgcg atcgttcgcg aagacagctt gtcgaaattt gccaaagaat
    12721 gtcactttga tcaatatgtt ttgttgggca agggagaaga gaattcagga ggacgtacgc
    12781 gaccagcatt gctttgcgac ctattcgaag cttttttagg cgcgttatat cttgaccagg
    12841 gattcgacac gacccatgca ttcatcgaaa aagtgatttt tcctaaagtc aaagcaggtg
    12901 ctttttcaca tgagatggat cataaaacaa aactacaaga agtcttgcaa aaatcaggtg
    12961 atgtatcaat cgaataccga ttgatcaatg aagaaggtcc agctcatgaa cgagtatttt
    13021 ggatcgaagt ttatgtagat gatcaattga ttggcactgg acaagggaaa tcgaaaaaat
    13081 tagcagaaca agctgcggcg gaaaatgcat tggcagcact gtaaaagtaa gtgagggaaa
    13141 gctttgtatt tgaaacgaat tgaaatagcc ggttttaaat catttgcaga caagacagtc
    13201 attgattttg aaaatagcgt cacagcagtg gttggaccaa atggcagcgg aaaaagcaat
    13261 attacagagg ctatccgctg ggtattagga gaacaatctg ctaaaagtct gcgaggcgga
    13321 aaaatgccgg atatcatctt tgccggttcc gatacccgta agcagctgaa tattgcagaa
    13381 gtcacagtga ttttagacaa tagtgatcat tatctgccat tggagtacaa tgagatcagt
    13441 gtaacccgcc gttatcgacg gactggggaa agcgagtttt tcatcaataa acaaagctgc
    13501 agattaaaag atatccaaga attgttctta gattctggat taggaaaaga atcgttctca
    13561 atcatttctc aaggaaaagt agaagcgatt ttcagtagta aaccggaaga ccgtcgtggg
    13621 atctttgaag aagcagctgg tgtcttgaaa tacaagcagc ggaaaaagaa agcagaacag
    13681 aagctttttg aaacagaaga caacctcagc cgcgtccaag acatcatcca cgaattggaa
    13741 gaacagttaa ctcctttggc cgcccagagt gaggcagcaa aggagttttt acggctaaaa
    13801 gaaacactga ctcaaaccga tgtctctttg atggttgctg aaatcaagac agcaaaaaaa
    13861 gattgggaca acaaacaagc acagcttgcg aaattcaatc tagaattagg caaactatct
    13921 gagtcgatcc aagaacaaga atccattttg gcgaagcagc gtaaagaaaa tgcgcaagcc
    13981 gatcgtctga tcgaaaaaaa tcagcaagta ttattagatc tttcggaaaa actgaagcag
    14041 acagaaggac aaaaagatgt tttgcaggag cggacaaagc atacacaaaa aagctcgcaa
    14101 gaatatcaaa cttcattagc agaagcacaa aaaaaggtta aacattttga aaagcttcaa
    14161 gaaagcttga tgaaagcagc agcagaaaaa gaaacagaga tccaaaaagc tgaagcaaat
    14221 ctcataaaaa cacagcaaga attagaaaaa taccaaaaat caacgaaaga attattggca
    14281 gaattaagag atcaatatgt tgatttgatg caagaacaag cagctgtagg aaacgaactg
    14341 aagtatctag aacgtcaata tatacaagaa acagcaaaaa gcaagcagac gttagccaag
    14401 caatcggaag tagaagcatc agtagaccga ttgatcttac aaaaagaaga attgacacaa
    14461 aagcaggcgc agctaaaatc atctttaact gaaacaaaag agaagttaga aatgatccaa
    14521 caaaacggga aaaagttcca agaagcatta gcaaaagaac agcctaaaat gtatcaatta
    14581 atgaatcaag tccagcagct acgtgctcgt aagaaaagcc ttcaagaaat ccaagaaaac
    14641 tattttggtt tttaccaagg ggttcgattg gtcttgcagc ataaacagca gctttcgggt
    14701 attgtcggag cagtggctga actgatcgat gttcctgcag atttcacgtt agctatcgaa
    14761 gcagctttag gtggggcagc ccagcatgtc atcgttgaaa atgaaaaaga tgctcggcaa
    14821 gccatcacgt atttgaaaca gcaaagagga ggaagagcaa cattccttcc actgacgaca
    14881 atcaaaccaa gacaattacc ggctcatata ttgacacaag cagcagctgt agaagggttt
    14941 atagggattg ccagtgaaca agtcagttat cccgatcaaa tccaaactgt ggttcaaaac
    15001 ctgctaggaa cgatcctttt agccaaagac ttaactagtg ccaatgcaat cgcgcaaacg
    15061 atccgctatc aatatcgagt ggtttcctta gaaggtgatg tgatgaatgc cggaggatcc
    15121 atgacaggtg gagcgaataa acgaggaaac caaggcagtt tgtttgtaca aaatcaagaa
    15181 ttgaaacagt tgactagtga atttgaagaa gcagataaac aactccaagc acaagaaaaa
    15241 aaagttcagg agctgcaaca agaaacagct cgtttagccg aagaacaaga agttttgcgt
    15301 acacgaggcg aacaattacg ttttgaagaa caagaagcga caaatcagct acaaaacatc
    15361 ataaatgaac ttgaacgttt tgaaaaagaa aagcaaatct caacttttga gacacgtgaa
    15421 ctgcagcagt ttatcgaaga ttacgaaaag caaacgaacg aattgaaaga caaacaaaca
    15481 gatcttgaat cgcaacgaca aaaaatcgac gaagaaatca aatcgttaag tcaagaaagc
    15541 gaccagatgg aagccagaag agcacaagta caaagtcaaa aagcacaaga acaagcagat
    15601 cttgctgtct tgaaagagca gtttaatcat ctgcagatcc agctccgcgg tgcccgagtc
    15661 caaaaagcag aggcaaccga acgtcaagaa gcgatagaaa agcagttggc gacattgaca
    15721 gcagactttt ctgatcatga agtcacagaa gaaagtttgg aaaaacaaat taacgaatta
    15781 tctgctcagc gagaaacatt aaaagccgag ttggcaaaag ccaaagagca gcgagataga
    15841 aggcaaaagg agatcgataa gcttgaagca gtcttggcag agcgtaatcg tgagcaaaaa
    15901 gcacgactgt cggaacaatc caaattagaa gtccaaaaag accgagctga aatgatttta
    15961 gataatcatt tgacctatct gcagtcagaa tatcagctga catttgagaa agcttcccaa
    16021 gactatcaag aaacaaccga tatcgaagac agtagaacaa aggtttcatc cttaaaagaa
    16081 cagattgaaa aactgggacc agtaaactta aattcaatcg aacaatacga acaagtcagt
    16141 gaaagacata cattcttagc aacacagcga gatgatctgt tagcagcgaa aaaccaattg
    16201 tttgaaacga tggatgagat ggatgatgaa gtgcggacaa gattcaaaga agtatttgaa
    16261 gctatccgtc aagaattcaa aattgtcttt ccaaatatgt ttggcggcgg taaagctgaa
    16321 ttagtactga cggaaccaac tgatttgctg aaaacaggta ttgagattga agtacaacct
    16381 cctggcaaaa aactgcaaag tctaagtttg ctttctggag gagaacgagc acttacagcc
    16441 atcgcgttgc tcttttccat tatccgtgtc tgtcctgttc cgttttgtat cttagatgag
    16501 gtagaagcag cgttagatga agccaacgtg aaacgttttg gtcgttactt gagcgatttc
    16561 caagatgaca cacaatttat cgtagtcaca caccgcaaag gaacgatggt cgcagcagat
    16621 gtactgtacg gagtgacgat gcaggaatcc ggtgtatcaa aaatcgtttc tgtacggatg
    16681 gaagatatca atgaagaggc gaaaatcaac gaaacgaaag tgtaggaacg aaaatgatca
    16741 aattagtagc aatcgatttg gacggtacat tattaaatga acaaaagctg atttcagatg
    16801 agaataaaca agcattagca caagcaaaac agcaaggggt caagatcgtt ctatgtacag
    16861 gacgcccctt agctgcgatg gcgcattatc tgcaagaatt aggactggta gatgaaggtg
    16921 actacagcat cactttcaac ggcggtttgg tacaaaaaaa tgatactggt gaaatcatgg
    16981 aaaagaaagt gatggaagta tcagatatcc aacgcttata caaactggct cagcaattgg
    17041 atctgccact agatgttttg tctgacaatg tggttttaca gctgcctagt gccccaagga
    17101 agcaatcctt gtacaatgtg ttgaataagc tgctgcaatt ccaaccagcg gatataagcg
    17161 atattacaga tgaatttgtg cttaataagg cagtaatcgc ttatgaccaa gaagaattag
    17221 atcctaaaat caaagaaata ccagcagaat tccatgaaat gtatgagatc atcaaaacaa
    17281 gaagtatgct tttggaattt atgccaaaag gtgttacaaa agcttatggt atttctttat
    17341 tggcaaaaga tcttggtttg aaacaagaag aaatcatggc gatcggtgat gaggaaaatg
    17401 atttaccgat gatccaatat gctggactag gcgtagcgat ggagaatgct gtgcctttcg
    17461 tcaaagaagc agcagatttc gtgacagcca gcaatgaaga aaatggcgta gccaaagtga
    17521 tccaaaaatt tgtattagag tagggggagt caaatgggat tttttgataa aatcaagcgt
    17581 gcttttactg gcgaagagaa aacagaagaa gttgaagtac aggagaagta cgacaagggt
    17641 ttagaaaaga cgcgtaaaac atttggtgaa cggatgaatg agttgtttgc caattttcga
    17701 acagtcgatg aagacttttt tgaagaatta gaagaaacac ttatcggtgc agatgtaggt
    17761 tttgaaacag cgatacgaat caccgaagca ttacgtcaag aagtgaaact cagaaatgcg
    17821 aaaaaatcgg cagaagtcca aaatgcgatc atcgagaaac ttgtggatct ctatgaagcg
    17881 gaaggaatca atgaagtaaa tgaactaaat atccaagaag acggactaac agttattttg
    17941 tttgtcggtg ttaatggtgt agggaaaaca acaagtattg gtaaacttgc ccatcagttc
    18001 aaaaacgaag gtaaaaaagt attgatggca gcagcagata ccttccgcgc tggagcaatc
    18061 gaccagttag ttgtctgggg cgaacgcgct ggtgttgaag ttgttcgtgg caatgcagga
    18121 ggcgatccag cagctgtcgt attcgatgct ttggaaagag caaagacaga gcaggcagat
    18181 gttttactag ttgatactgc aggccgactg caaaataaag tgaacttgat gaacgaatta
    18241 gaaaaaataa aacgagtaat ccagcgggaa ttaccagaag caccccaaga aacacttctt
    18301 gtattagatg caaccactgg tcaaaacgcg atggttcaag caaaacaatt caaagaaaca
    18361 acagatgtga ccggtcttgt tttgacaaaa ttagatggta cagcaaaggg cggtatcgta
    18421 cttgctatcc gtaatgaatt gcatttacca gtgaaattgg tcggtcttgg tgaaggaatc
    18481 gatgacttgg agccgtttga tccaaatgat tttgtcgttg gattgttcaa aggattacta
    18541 aaagaagaat aacccatgtc taaaaagcag gagctgtgac aaaagttgca gctccttgtt
    18601 tgaatgattg tttttaacat agctgtgttt ttgatgcctt catttttata cttatttgta
    18661 agcggttctc aaacaatttc gttctttttc ttagactttt tgattataat tagattcata
    18721 tgaattggag gtcacttaat gatgaatttt aagcaattat tattgcatgt caatgcgcgc
    18781 ccttttatcg accaagctcg atttggtata gaacgggaag gacagcgggt tgatcttgca
    18841 ggaaatctag caaaaaccga tcatccagca atctttggcg atcgatccta tcacccctat
    18901 atccaaacag attttagcga aacacaaaca gagatgatca cccctgttac cgattctatt
    18961 cccgaattat ttcagtatct cgctgctgtt tatgatgtga ctgctcgttc tataccgaaa
    19021 gaagagatga tctggccatt aagtatgcca cctgccttac cggaaaaaga cgaagagatc
    19081 attattgcaa aattaaaaaa tttcgaagat gtcttgtatc gacgttattt agcaaaaaaa
    19141 tacgggaagc gaaaacagat ggtaagcggt attcatttca attttgaatt tggcgatgag
    19201 ttgctaagaa cattgttcag ccatcaggaa gaatttcaag atttttccga attcaaaaca
    19261 gaactttatt tgaaaacagc gagaaacttt atgcgctatc gctggatgat cacttattta
    19321 ttcggtgctt caccaatgag tgagaagaac tactttttag atgaatcaca tccgcaagaa
    19381 cctgttcgca gtattcgcaa cagtgcgctg ggctatacga atcatccaaa tgtgaaagtt
    19441 tcctatgctt ctatgaaaca gtatttagca gatatcgagc gaatgatcga agaagggaaa
    19501 ctttcggagg agaaagaatt ttatacaccg cttcgtttcc gaggcggaaa gaaagtcgca
    19561 gatttagcaa caacaggtgt tcgttatatt gaattgcgga atatcgattt gaatccttat
    19621 gcaagattgg gtatcaatcc agagcaagtt cggttcttac aattattcct gatgtacatg
    19681 ttatggacag aagaaaaaga agactgtgac caatgggtag cagaaggtac gactcgaaat
    19741 aacaaagtag cactagaaca accatcagat caaacagaat ttcatcaaga aggtagagaa
    19801 attcttgaag gaatgaagca aatgctggtt gaattggatt ggttggattc tctttattta
    19861 gtagaggaag cattgactca aatggatcat cctgaacaaa cgttagcagc gaaactctat
    19921 caagaagcac agctatcgag tcagcaagaa gttgctgtgg cattgggaca tcaatattat
    19981 aaagaaagcc atgaacgtcc ctatcagttg gccggttttc gcgaaatgga actttctact
    20041 cagatattta tgttcgatgc catccaaaaa ggtgtccaag tcaaagtatt agatgagtcg
    20101 gatcaatttt tgcgtctgca attccaagac catgtagaat atgtgaaaaa tgcaaacatg
    20161 acaagtaagg acagctatat cgtcccactt atcatggaaa acaaaacagt aacgaaaaaa
    20221 gtcttaaaag aagctgggtt ccgggtacca ggaggcgcag aattttcatc catggaagaa
    20281 gcggtaaaag cttatccgag atttgccgag caggcatttg tgatcaaacc taaatcaacc
    20341 aattacgggt taggtatcac gattttcaag gaaggagcta gtctggaaga ttatcaagca
    20401 ggtttagcca ttgcttttcg tgaagacagt tcggttttag tagaagaatt tatgccggga
    20461 acggaatatc gtttctttgt gatcgacgga gaagtccaag ccatcatgtt gcgagtccct
    20521 gctaatgtta ttggtgacag tatccgaaca gtgaaagaac ttgttgaaga aaaaaatagt
    20581 gaccctttgc gtggaacgaa tcatcgtgca cctttagaat tgatccaatt aggtgaatta
    20641 gaacaattga tgttgaaaga acaagggttg acgatcgaat cagttcccca agccaatcaa
    20701 attgtttatc taagggagaa ctcaaatatc agtacaggtg gtgattcgat cgatatgact
    20761 gatgaatttt ctgaagctta caaaaaaatc gccgtttctg cggtagaagc actaggagct
    20821 aagattagtg gtatcgattt gattatacca gataaagaaa tcgatcctac aactgataaa
    20881 aaagcatatg ggatcatcga agcaaatttc aatccagcca tgcatatgca tgtttatcct
    20941 tttgcaggaa aaggcagaag attgacgatg aatgtattga aattgttata tcctgaagta
    21001 ttttaaaaga aaaagctttt gacagattgt cctatttgat gtcaatctga tcaaaagctt
    21061 tttttgcatg taaaaattta tgtgtttttt cgttttaaaa taaacgatcc cagaagcttt
    21121 ttttcttttt tggtttttct ttttcagctg gcgaagagtt ttcttctggg tatttttttt
    21181 cgatatcaat cacaggttca tttactgctt cttttgctgt taagagcaat ccgaattcct
    21241 caggatttgc agtgacgtaa tcgttgacta cagtgaaacg gctattgttt ttcgttgcta
    21301 gctggatata ttggttttgg acagaaaggg gtagagcccc attcaagagt atggaagcat
    21361 ctggatgttt tttgagttct tttaaaaagt tttctttgtt ttttggttgg atcatttcag
    21421 caacagtcat actaagatag cagcgttccc tgaatgtccc taaatattta tgctgttctt
    21481 cagggttcac taaaggtgta ccataaagtc ccttatccaa atggcttttt acatcatctt
    21541 gtgccataaa aaataccctc cttcttctct ttgtctttct tacgattata gcatattccc
    21601 aataatacct aaaacatatg aaaaagcggt tgcttttgtt caacgattca cttaaaataa
    21661 gaatgaaaat cattctcaat tagaaaggtg gattggatgc gctacggacg actagtagca
    21721 ttattagtta ttttaagtag tatttcattg ttcatcggag tatcgaatgt acaattgtca
    21781 gaactgctcc agttagatgg gcaaagctta caaatcttgc tagtgactcg tttgccacga
    21841 acgatttgtt tgatccttgt gggagcgacc agtagtattt gtgggttgat catgcaacat
    21901 ttgacccaaa ataaatttgt ttcaccaacg actgcgggca cgatggatag tgcgcgttta
    21961 ggtattttag tggctatgat tttcctacct ggtgcatcct tgattgtccg atccttgaca
    22021 gcattttgct ttgcttttgc aggaacattg ctttttttat cccttacgcg attgttcctc
    22081 cagaaaaatc aattgatgct tccgttgatt ggagtcatgt tagggaatat cattggttca
    22141 gttgctactt tttttgctta tcaattccag ttggtacaaa atatgacttc atggcttcaa
    22201 gggaattttg cgactgtgat acgaggaaat tatgagttat tgtatgctgt tgttccattg
    22261 ttgctcttgg tttggctatt tgcttaccga tttacgatca ttggtctggg cgaatcgttt
    22321 gcagtaaatc tgggaataga ttaccagaag atgcagtttt taggcattgg cttagtatca
    22381 ttggctagtg cagtcatgtt gatcatggta ggaagcattc cttttatcgg agtgatcatt
    22441 ccgaatcttg tctctagaat atatggagat caagtgcaca aaacaattgg cgtaactgct
    22501 ttagcaggta gtttgttctt agtattttgc gatcttgtcg ctcgcgtgtt gatttttcct
    22561 tatgaaatac cagtcagtgt gatcgttgga atcatcggtg gggctatctt cctttatctt
    22621 ctgataaggg gacgacgata tgcttaaaaa aaagccatct atttttattg gtatgcttgt
    22681 tcttgtttta tttgttacag gaatgtactt gacgatccat acatatggaa actggcattt
    22741 tgcatgtgca ttgaggagta agaaaatttt tgcatttatc cttgtctcgc tagctgtcag
    22801 cagtgccaca atcagctttc agacaattac gcataaccag tttttgactc cttcagtatt
    22861 gggacttgag tcgttatatg tccttgtcca aacggtcctt ttcttcttta tcggaggagt
    22921 gacgatgctt cagcagacag gtacagtttt tttcttattg aacgttgggc tgatggtcgg
    22981 gctgagtcta ttgttatttt tctttctttt gaaaaaaatg agagcgaatc tttttttatt
    23041 actgatgtca gggatgattt taggtacgct ttttggtagt gtcagtacct ttttacaagt
    23101 catcatggat ccgaatgaat atgatttgct tcaaggcaga ttatttgcaa gctttggcaa
    23161 tatccagagt cagtatcttt tgcctgcttc tttgatcatt atcggctgct ggtacctgtt
    23221 atttcgatat cgacatgtgc tagacgtttt ccatctcgga aatgaacaag cagtaaacct
    23281 cgggatagac acagatcgtt ttgaattttt gattttatgt tgtgtcagtc ttttgacagg
    23341 gacatcaacg gctcttgtgg gtccagttac ttttttaggg tttattgtcg caaatatcag
    23401 ttatcgtgtc ttttctactt atcgtcatgg tcagctattt atcggaagct ttctggtagc
    23461 tatgctgttt ctgacaggag gacagctcgc agtagagcag attttcggct ggaatacaac
    23521 agtgagtgtc gtcgttgaat ttgtcggagg aatttatttt gtcacaaaat tgattcgcga
    23581 aaggaagagt atcctatgat tgatttacaa aaggtcaata aactgtacca tggaaaatca
    23641 gtggttaaag atgtacagtt aacgattcct gaaaagaagt tgactgcttt tatcggtcca
    23701 aatggtgctg gaaagtcaac ggtgttgtcg atgatcagtc gtttgatacc aaaagataca
    23761 ggtgaaatct atttagacca taacgaagta aaggcttgga aatccaatga attagccaaa
    23821 aaattatcga tcctacgaca atcgaatgaa ataaatgtcc aaatcaccgt gaaagaatta
    23881 gtagaatttg gacgatttcc ttatacgaaa ggaaaattga cgacaaaaga cgaggaaatc
    23941 gttcaggaat cactggaaca ccttgggtta gaagaaatag cggatcaatc gattgacact
    24001 ctttcaggcg gtcaactcca acgtgcgtat attgcaatgg tgctagcgca agacacggat
    24061 tatattttac tggatgaacc tttgaacaat ctagatatga attttgcggt tcaaatcatg
    24121 cagattttaa aaaatttagt acaagaaatc gggaaaacaa ttgttattgt tcttcatgat
    24181 atcaactttg ctgcaagtta tgcagacgaa attgttgcaa tgaaagatgg acagttattt
    24241 acgcaaggaa cgacccaaga aatgataaaa aaagatgtat tggatgaatt atacgaaatg
    24301 gacatacgga tttgtgagat tgaaggccgc agattctgtc tttatttcta aaactaacat
    24361 taggagagaa gagatgaaaa aattagtagt aggtatcttg attctagcat catttggttt
    24421 agcagcatgt ggaaatagca acaacaccag tcaggcagac acaaaaaaaa gcagcacaca
    24481 aactgaaact acattgacga taacagatag taatggagac caaatcgagg tgccaaataa
    24541 tccagaaaaa gtcgtcgtat tcgacaatgg ttctttagat acgatggatg ctcttggtgt
    24601 tggagataag gtagttggag cagctacaag cagccttcct gagtatcttt catcctataa
    24661 aaaagtagaa tcagcaggtg gaataaaaga accagactta gaaaaaatta atcagcttca
    24721 gccagatcta atcatcattt ctggccgaca aagagatttt caaaaagatc taagtcaaat
    24781 tgctccgacc attttccttt ctttagatgc gaaaaatcca tgggaatctt tccagcaaaa
    24841 tgtcactgct ttaggggaga tctttggtaa gcaagaagaa gctaaaactc aattagagga
    24901 attatctagt gcaatcgatc agacgaaaaa gaaagcagaa gctactgaca aaaaagcact
    24961 agtcacactt gtgaatgaag ggcaattatc agcctacgga tctggttcta gattcggttt
    25021 catccatgat ttatttggct ttgaacaagc agatgatcaa atcgaagcat ccactcacgg
    25081 tcaaagtgtt tcttatgaat atgtgctgga aaaaaatccg gatatcttat ttgtagtaga
    25141 cagaacaaaa gctattggtg gagacgacag caaagatgat atttctgcca atgaactggt
    25201 agcacaaacg aatgctggta aaaatcagca gatcatctcc cttgaaccag atgtctggta
    25261 tttaagcggg ggcggtttag aatcaatgaa actgatgatc gaagatgtga atcaagcatt
    25321 taaatagcat aaataacaga ggattaaact ctcatactat gtaacaataa tgtttcttac
    25381 attcttaaat agcaagagcc tatcctcaaa gaagttatca aaaaccatcc gtaaaatcgt
    25441 attgatgatt ttacggatgg tttttattta tttgagaaat cttttttcaa cgtgaattca
    25501 ttatctacat catacgggtt gattctagaa tggggagtgg caaaaaatag tgtgatccat
    25561 tttttcagca tcaagatcgc ctcctttgat ttgaatcaaa ggtacaaagc gaaacttaga
    25621 taaaacttaa atttagatat ttttattttg taccgatctc ttctttaaac gatgttccat
    25681 ctgctgcttc tcggcaataa gtccactaga ctagaaaata tgagaagcta ttttctgtcc
    25741 agcgttctta ttactcaaaa caaatcgcag ttgtcacaat ctcttctaaa cgatgttcca
    25801 tctgctgctt ctcggcaata agcccactag actagaaaat atgagaagct attttctgtc
    25861 cagcgttctt attactcaaa gcaaatcgca gttgtcacaa tctcttctaa acaatgttca
    25921 atcagctgac cttcggtatt agctcaaagc actgatttca caacctctat ttaggcatgt
    25981 gtctcagcaa gcggttgata gttgatgatc tgcatttttc gataaaaatc ggcgggaagc
    26041 ttactccacc gttttagtaa ttgatagaaa taactctctt ctgctttgat tttatactcg
    26101 cttaatatca atccaaaact attcgttttt tttgaagcta attttttata aatatccaat
    26161 gctttggttt tatcttcatt gacaaagagt gtttttactt caatataaga accctcgata
    26221 ttttgtgttt cttcgataaa atagatgttt tttatatatt ccttcatagt gattcctcca
    26281 aagaagtctt ttatttgata agtttactct accgaagagt tgttaataat ccgtgaacaa
    26341 aaagtaattc tttttccaat agttgttaaa ggttttttat tttttatagt attttttgtt
    26401 atttaagaaa ggaataaggt taaacaaata acaggttgct ttttgggtct ttttccgttc
    26461 aagaaactga acgaagaaaa gggaaagttg tctcttttgt gataagagaa atcataataa
    26521 acgaatgact tactttccaa taaattgaga acagtcagaa ccagacaaat tagttgcatc
    26581 tgatgaataa agtgattatt ctatgacatg aggtgataca gatgaaatta gaagtgacaa
    26641 aagaagcaca agaagtattg aagaataaat tagaagcaga cgatcaactt ttattagata
    26701 tcgaaaacgg tgacggtcca tttgcagaaa gccaagtcag ttgccaattg gatacggcat
    26761 ttcgattgat cattgtcaaa aaagatacac aaacagatct aagtctttat tctgtagtgg
    26821 ctgatacacc agttggacca atcaaaatca aagacagtgc aatactttac atggatgatc
    26881 catccacact tgctttagaa ccaacttata atagtttaca attaaaagga ccaagcggct
    26941 tgagaaaagg caacttgcaa gttgttcgaa aagactagag ggataaaatg ggaaaattgg
    27001 cgatcatcag cgacctacat gtggacatca ataaattcgg cgaatcagag ctgatgcagc
    27061 tttggcaagt tttgcaaaag cacaagatca ctcggcttca tctagccgga gatacggcta
    27121 ataaagtaga ccgttgccta gctgttgtcg aatttttcgt caataaagga ttatctacga
    27181 catttcattt cggcaatcac gagttggcag atgtgcccaa tgaacagatg atggaccatt
    27241 ttccagaccc acatttttta aatgaacggt atattgcttt aaatgagcag accgttcttt
    27301 tagggatgaa tggctggtac gactatcagt tttccgaatt gaaagattac gaggcaatcg
    27361 tacgaatgaa gcgtttgtat tggtatgatc ggttcatcca gcgtgggaaa acagatctcg
    27421 aggtcaatgc agaaatgctt gcagctgcaa aaaatttgct agaccagctg gaagcaaaaa
    27481 aacttgaggt gattttatcc actcatttcg ttcctaaacg ggcatttatc atgtatcaat
    27541 ctgctcctta tgagcgttgg aacaaattaa atgcattttt aggatcagaa tcattcggag
    27601 aattacttga ccgttattca aatatcaaac aagtagtttt tggccatacg catcgtcgct
    27661 ttgaagataa atccatcggt cacacgattt acagctgcag accttttggt tattattatg
    27721 aatggcagct gacccgagat tttgtcttga aagaacagtt gctagacagc tatgatccta
    27781 tgaaattacg tgtcctcttg cgtgcccatc acccagcttt tcaggcctat caaacacaac
    27841 atttgcaaga ggaatttgaa caagcgatga caatcgttcc gtattgagac agcattagta
    27901 atgtgtaaaa gaaaatacct tgtaaaacat aaggataagt aagagcagta gatccattta
    27961 tcgtggatat gctgcttttt ttgcggaaaa taatcagcga atgtttattt gatcggatga
    28021 tttgtaactc gcagagtact agatgcaagc gtgtattctt tttttgaacg ataatcacaa
    28081 aaaaaaatat aatatacatt ttttatttaa ttataattaa tattgattga agtctaggca
    28141 gtcaagtcac attttgatag ataggagggg gacttacgaa ttattttaaa ggctatgaca
    28201 gctgtatttc tagattgtgt ttgcatcaag ttgcaataaa aactagaaat caaatcgggc
    28261 tgataatcat ttataactaa tcgatacata ggaccaaata taggtctatg ttcttttatt
    28321 tcataagtat cgtaaaacag aattttgcta tggattaatc caatcgactg atatgtttag
    28381 taaataaaga aagaggaatg tcaatgatga aaaaagaaat cgtattaaca gcagcaatga
    28441 tgttattcag catggtagca agtacgactt ttgtttctgc aactgaagta tacccaaagg
    28501 aatataacac agaaggaacg attacatttg aagcaggaga tgagggtgta actcctcctg
    28561 ttgatccaga gaatcctgat cccaataaac ctgtcgatcc atcagatcct ccaagccctg
    28621 gaacaggagg ggcattatcg attgattatg gatcaaaatt caaatttggg actcaaaaaa
    28681 tttctactgc ggataaaacg tattatgcag ctgctgatgt gatgaacgat gggtctagaa
    28741 aaccgacata tgtccaagtg acagatagga gaagtacctt atctgggtgg aaattaagtg
    28801 tctctcaacc agaacagttt aaaactgcca gtggggatga actagttgga gcacagctga
    28861 aatttacgaa agggcaggct gtttctttgg ttgatccaac atatacgccg caaacggtga
    28921 attctgaatt aacgttgaca ccgggaggaa acaatacgtt agcaattaat gctaaatcag
    28981 gaacaggtgt ggggacttgg gtctatcgat ttggtgcaaa tgaaaatgaa aatcaagatg
    29041 cggtacagct ttcggtaccc ggtaaatctg tcaagttagc gcaacaatat tccactaaat
    29101 tagtttggac attagaagat acacctaaca actagtttac tgaaaagaac tgttaaaaat
    29161 aaatacgtag tcatattgtc ttgcgaggta atcgagcaaa aattgtcaaa ggctaggcta
    29221 aatttgtttg gatacgaata gttcatctag gaatttaacg atcaggagga aaagatatat
    29281 tgaaaaagag gaggatcgtg ctcattttaa gcagtctctt agtgactaat atctttccga
    29341 tcatagggta ctctttggaa ttgaatcagt tggagcatgg aaatagaaga gacgaagaaa
    29401 gcaaactcac ttcgacattc gacagtttaa tagaatccaa ccagacacaa gaaagcagtg
    29461 aggatttaag tatttcgagt agtggagaga ccactgacaa cgtagaagct gagggttcgg
    29521 acaaacaagg actagaagat gcaccaattt ctgcggttga gctgcctgac gatcccaata
    29581 ttatttctat cgataaaatt tttcaaacac ctatcggtac tagcacgtcc atattggaaa
    29641 atgggaagtt actgcagttg aacccagcag aaaggtctca aagaggagct atttggtcaa
    29701 ataagaagat tagtttactc tcggatttta catttaaatc ttatttatac ttaggaaatc
    29761 aacgagatag agcgggagat ggcatgacct ttacattgac tggcgatcct agaatggcta
    29821 gtaatcccag tcaagttatt ggatcgccag gtatgggaat tggctcatat tctactcgtt
    29881 ctggccaacc ttacattgcg aatgcgctct cgattgagtt tgatacgtat aaaaatagtg
    29941 gttcttctga tcgaatggat cgagagataa ctgctgataa tagagggcat ggacatgtcg
    30001 cttttgtcac gcctaaacca aataataata attattctgg agagcatact ggcgtgacgg
    30061 tagctcctac atttctttct aatggcacat ggcgcttgtt aataattaaa tgggacgcgg
    30121 agcaaagaag tcttacttat gatttggaag gtgtcggtcg ctcttctcgg attatacctg
    30181 atctcattag gcagtttggt tctacagaag taaattgggg gtttacttct tcaacaggta
    30241 ctttttttca agaaaatgct gtcgctgtca cgcgacttcc atcgaatgtc acatcaacag
    30301 ctgatgtaaa agtcaacgat agtgattatg gggccatcgc tgaagctgga ggaaacgata
    30361 agataactat cagaaataca ttgaaggtcg agggggattt tcttgaatat aagaaaatgc
    30421 agactagtat cgacctccca caagaattaa ctattcccga gcatatcttg atcaatggaa
    30481 atcaaattga tgccaaagat atcttgataa ccggaaatcg agtcacgcta aatctgacag
    30541 attattttat tgctggagat acgttaataa tcgaattgga gacaactttg caggaagtaa
    30601 ttcctgaaaa agtactcact atgcattttg aataccttga aaacgggaat ttgattgagc
    30661 aatcgaatga aataaaccta aagatcgcaa agctgaagga gatagatatc catgtttatt
    30721 ataaagataa agacagtcag attgatattg ctgaaatgaa aacaatcact gggaaaatag
    30781 gagagaagta taaagaaact cctattgata ttgaagggta tgtttttgac tcggattcag
    30841 cgaatacaga aggcatcttc tccgaaaata cagaggatat ctatttttat tacagaaaag
    30901 gcaaacttta tctctcaact gctcctcaat atgtcaattt tggaaaacat aaaatatcca
    30961 gtagaccatt aagtgaattc ggacagtttt caggtgggtt gaaaattata gatgaacggg
    31021 cttttggaag ttggaaatta caattgaaac aagagaaagt tcttacaaat ggagattttg
    31081 agcttccaga agctctttcc tttgttacct ctgaaaatac aacggttata gggacatccg
    31141 ctgttacgat tttcgaaagt gatcaaaagg gtgaaagcga tttgtcctct cttttagatt
    31201 ctacagctca tcgtggaatc agaataaata ttcctgtaga aaaccaaaga atcggaacct
    31261 ttgaggggaa actatcttgg atacttgcag atgtcccagg aaattaacag gaagagaaga
    31321 atataacaaa attattgagt ttcaagaagg gcacaggtac cataggctct tgtgtcccac
    31381 agagacaaga ttttgttata gtcttctctt acatatgatt aaaggagcga ttttcttgag
    31441 accaaaacaa caattattta taacactcct agttatttta ggggcacttt ttaacaatat
    31501 atcagtgtca gctagtgcat ttaatttttc agtgacgccg ataacttcag agaatcaaat
    31561 cgacaagaga aaaacttact tcgatcttca acttgatccg gatcaggaag tagaagtaaa
    31621 agcggaattg agaaatgata cagaaaaaga agtgaaaatc gatatttctg tgaatagcgc
    31681 aaccaccaat tcaaatgtga tggttgaata cggaaaaaac gagattgaaa aagacatgag
    31741 cctgatcttt gatctggtag attatgtgag ctatccacag atagtgacgc taaaacctaa
    31801 aagtgtccaa accgttgctt ttcatgtcag gatgccgaat gagcgatttg atggtgtatt
    31861 ggctggtggg atcacattcc aagaaatcca gacggaaaag gaccaaacag aaactaagga
    31921 tcaaagctta tcgattgaga atgaatacac ctatattatt gctttgttga tgcaacagac
    31981 actgaacgaa gttgctccga accttactct tcatgaagtt aaaccagatc aaatcaatgc
    32041 aagaaatgtc atcttagcaa acgttcaaaa tgatcaaaaa acctatatca atcaagtagt
    32101 tattgaaaca aaaattacaa aaaaaggaca ttctgaagtt ttatatcaag aggaaaaaga
    32161 aggattgcag attgcgccga atacaaattt ttcttttcca actgctttaa atggtcaacc
    32221 gctaacccca ggtgaatatc accttacaat gactgtttta ggaaatgaaa atgaaaatgg
    32281 aaaattttcg agaaaaaaag gaaatactac gatcaactat accaatcaat gggtatttga
    32341 aaaagatttt acaatagacg gaaaagtagc caaggaattg aacacgacgg atgttacgat
    32401 taaaaaagac aataattgga tttatatctt agtagcttca cttttcttat tgtttatttt
    32461 attatgcata cttttgtttg ttttgagaaa aaaagaagag aaagaaaagt aaggttaaga
    32521 taacaaatag taaattttta ttattgtagg atggttgggc tctttttata acaatataaa
    32581 atataccatt ttattaataa aaatgcatac tagtaaatga tataattcta ataacaggtt
    32641 tgatcgcgag aaaggccaaa taaaacgctc tccaaaatgt taaaaaaaag acaggacgat
    32701 gtatattata caaacaagaa tcgctgacaa cagtgactcg gatccaggaa atcagtttta
    32761 tccccagcta gttggtgaat gcatggaaag taatatacgt agaaagagct gatgactaat
    32821 gaattatgag ttttttttaa gcaaagaaga tcacagaagt tattcattac ttaaatattt
    32881 agaagcaagc tcaaatttat cagagtcaat atcgaatgtt caagaagagt tgtcgctatc
    32941 gacatttctc ttgaaaaaaa cgatcgataa gctgaaacat gatttacaaa agttcgatct
    33001 agagaaaaat ttgcgagtaa ccgtcagtga attggatata tgtctggaaa ttaatggaaa
    33061 atgttctagc aaagctctgt tatctcgtta tataacggat tctttatcta tgaaaatggt
    33121 attggctttc tttcaggaaa aatatatctc agtagaaaat tttgctaaac agcatcacgt
    33181 gagttattct gtggcttata aagtattaca aagactaaaa agaaatctaa aaaaatatca
    33241 aatttttttt gaaaagagaa agttga
//
LOCUS       DAYYEF010000031        31117 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000031 DAYYEF010000000
VERSION     DAYYEF010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31117
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.031"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(334..696)
                     /locus_tag="ACHA1B_001602"
     CDS             complement(334..696)
                     /locus_tag="ACHA1B_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702370.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(770..1150)
                     /locus_tag="ACHA1B_001603"
     CDS             complement(770..1150)
                     /locus_tag="ACHA1B_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvfD/Ygs/GSP13 family RNA-binding
                     post-transcriptional regulator"
                     /protein_id="HFM8702371.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1232..2407
                     /locus_tag="ACHA1B_001604"
     CDS             1232..2407
                     /locus_tag="ACHA1B_001604"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_function: GO:0047804 - cysteine-S-conjugate beta-lyase
                     activity [Evidence IEA];
                     GO_process: GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MalY/PatB family protein"
                     /protein_id="HFM8702372.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2484..3068)
                     /locus_tag="ACHA1B_001605"
     CDS             complement(2484..3068)
                     /locus_tag="ACHA1B_001605"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFM8702373.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3269..4267
                     /locus_tag="ACHA1B_001606"
     CDS             3269..4267
                     /locus_tag="ACHA1B_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFM8702374.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4379..4888
                     /locus_tag="ACHA1B_001607"
     CDS             4379..4888
                     /locus_tag="ACHA1B_001607"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008962 - phosphatidylglycerophosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HFM8702375.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(4918..5577)
                     /locus_tag="ACHA1B_001608"
     CDS             complement(4918..5577)
                     /locus_tag="ACHA1B_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HFM8702376.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5579..6343)
                     /locus_tag="ACHA1B_001609"
     CDS             complement(5579..6343)
                     /locus_tag="ACHA1B_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HFM8702377.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6351..7028)
                     /locus_tag="ACHA1B_001610"
     CDS             complement(6351..7028)
                     /locus_tag="ACHA1B_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HFM8702378.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7065..8450)
                     /locus_tag="ACHA1B_001611"
     CDS             complement(7065..8450)
                     /locus_tag="ACHA1B_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HFM8702379.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8660..8744)
                     /gene="ffs"
                     /locus_tag="ACHA1B_001612"
     ncRNA           complement(8660..8744)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ACHA1B_001612"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8767..9282)
                     /gene="tadA"
                     /locus_tag="ACHA1B_001613"
     CDS             complement(8767..9282)
                     /gene="tadA"
                     /locus_tag="ACHA1B_001613"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008251 - tRNA-specific adenosine
                     deaminase activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0002100 - tRNA wobble adenosine to inosine
                     editing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HFM8702380.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9389..10246
                     /locus_tag="ACHA1B_001614"
     CDS             9389..10246
                     /locus_tag="ACHA1B_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702381.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10327..10662)
                     /locus_tag="ACHA1B_001615"
     CDS             complement(10327..10662)
                     /locus_tag="ACHA1B_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702382.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10729..12099)
                     /locus_tag="ACHA1B_001616"
     CDS             complement(10729..12099)
                     /locus_tag="ACHA1B_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HFM8702383.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12177..12713)
                     /locus_tag="ACHA1B_001617"
     CDS             complement(12177..12713)
                     /locus_tag="ACHA1B_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8702384.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13022..14503
                     /locus_tag="ACHA1B_001618"
     CDS             13022..14503
                     /locus_tag="ACHA1B_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702385.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14606..15313)
                     /locus_tag="ACHA1B_001619"
     CDS             complement(14606..15313)
                     /locus_tag="ACHA1B_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HFM8702386.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15392..15730)
                     /locus_tag="ACHA1B_001620"
     CDS             complement(15392..15730)
                     /locus_tag="ACHA1B_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein YjdM"
                     /protein_id="HFM8702387.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(15841..16803)
                     /locus_tag="ACHA1B_001621"
     CDS             complement(15841..16803)
                     /locus_tag="ACHA1B_001621"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004527 - exonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008441 - 3'(2'),5'-bisphosphate
                     nucleotidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HFM8702388.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(16818..18149)
                     /locus_tag="ACHA1B_001622"
     CDS             complement(16818..18149)
                     /locus_tag="ACHA1B_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DRTGG domain-containing protein"
                     /protein_id="HFM8702389.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18157..18837)
                     /locus_tag="ACHA1B_001623"
     CDS             complement(18157..18837)
                     /locus_tag="ACHA1B_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HFM8702390.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19056..19535)
                     /locus_tag="ACHA1B_001624"
     CDS             complement(19056..19535)
                     /locus_tag="ACHA1B_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HFM8702391.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19662..21341)
                     /locus_tag="ACHA1B_001625"
     CDS             complement(19662..21341)
                     /locus_tag="ACHA1B_001625"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFM8702392.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            21889..23391
                     /locus_tag="ACHA1B_001626"
     CDS             21889..23391
                     /locus_tag="ACHA1B_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702393.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23404..24066
                     /locus_tag="ACHA1B_001627"
     CDS             23404..24066
                     /locus_tag="ACHA1B_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702394.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24167..24370)
                     /locus_tag="ACHA1B_001628"
     CDS             complement(24167..24370)
                     /locus_tag="ACHA1B_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HFM8702395.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24481..25665)
                     /gene="iadA"
                     /locus_tag="ACHA1B_001629"
     CDS             complement(24481..25665)
                     /gene="iadA"
                     /locus_tag="ACHA1B_001629"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008798 - beta-aspartyl-peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HFM8702396.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(25822..27561)
                     /gene="yfcC"
                     /locus_tag="ACHA1B_001630"
     CDS             complement(25822..27561)
                     /gene="yfcC"
                     /locus_tag="ACHA1B_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HFM8702397.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(28334..28948)
                     /locus_tag="ACHA1B_001631"
     CDS             complement(28334..28948)
                     /locus_tag="ACHA1B_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFM8702398.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(29554..29931)
                     /locus_tag="ACHA1B_001632"
     CDS             complement(29554..29931)
                     /locus_tag="ACHA1B_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702399.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(30231..31112)
                     /gene="galU"
                     /locus_tag="ACHA1B_001633"
     CDS             complement(30231..31112)
                     /gene="galU"
                     /locus_tag="ACHA1B_001633"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA];
                     GO_process: GO:0006011 - UDP-glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HFM8702400.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         9285 a         6465 c         5191 g        10176 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataactattt tttaaatttt
       61 ttagaaatgt gatataacat ccacttcaga atcaacgctg ttaaatttat catgtatttc
      121 ttccttggtc aactataaat taagcattac tttgtgaaat gatttttcga tcaattatta
      181 ttattcgtta tacaaccgtt ttcaacatat tttgaaaata aaatgcacta aaaaactatc
      241 tttagcagaa catttcattg tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa
      301 aattcaaact tctttgttcg cttaatctgt attttagaag aaaggcactc cctctacttc
      361 gtaagttcca agaacagagc gcatttgacc tggttcttcc caaatatatc cttcgcctaa
      421 ttcttctctt tgattctttt gttcagtttc aaagacaaac aacggaacat tttcctcttt
      481 aatatgtgta tttgtcaatt ccatcaaact aatcttgcta acatcgatat gaactatttc
      541 ttttaagaaa ttaagtatat tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc
      601 aaattccaac ttgtcatcaa ttgaatggac caaaaatttt ttagtaccat cctccaaatg
      661 caacataatt gtaccagcaa ctcttttgct tgccaaaatt tccacctcga tcaacttgtt
      721 ctatggctta cataaaaatt ctagcacatt ttcagaaaaa atacactttt tatttcttat
      781 tttctttccg ttctagttca gataatgctt cttctatcca aataggtaac tgctccgcaa
      841 tagtggtaaa tccgatctta cgatttttat tcgtgaaata cctttttctg cgatatggaa
      901 cagctggatt tgttttttct aacgttctta aagataaact gatttttttg gaatattcat
      961 caatgtcgat gatctgaact gttactggct gtccgacttt taacaatgaa tggatatttt
     1021 tcgtataacc ggattgtact tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag
     1081 aaacgaatgc gccataaggc tgtatccctg tcacttttcc ttcaattatt tgtccaattt
     1141 tataagtcat ctacttccct ctcttcgcat ttatcattat actgtaaata gctcaaaaaa
     1201 agaagcgacg aaaatgactg gaggtcttaa gatgatcgaa tttgataaac agatttcaag
     1261 aaaagataca gaaagtgtaa aatgggacgc aattgctgag acatatcaaa tggatgactt
     1321 acttcctttg tgggtagcag atatggactt cttgtctccc ggtggggtag ctaaagcgtt
     1381 tagtgaatac atcaaacatg gaatctttgg ttatgccact ctgtctgata aactatatca
     1441 ggctatcatt cattgggaac gccaacacca tgctgtggag ttgacgaaag aaaatatcgt
     1501 ttttacaagt ggtgtgttaa ccagtttagc tgcagcagta caaactttta caaaaccagg
     1561 cgattctatt ttgattcatg acccagttta tcctccattt tcctctatta tagaaacaaa
     1621 tcaacgtcac atcgttcgaa gctctttgct agaaaaaaat aatcatttca tcatggactt
     1681 gtctgacatg gagaaaaaaa tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc
     1741 tcacaatcct ggagggcgtg tttggagcaa agaagaattg aaacagttaa gcgaattgtg
     1801 tttaaaacat caagtgattc tgtttagtga cgagatccat caagatttaa ctttattcga
     1861 tcatacattt acttccatgc taacgattga tcctaattta gatgatctac tagttgcttt
     1921 tacttccgca accaagactt tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa
     1981 aaatccagag atgaaagctg attttgaaaa acatttagtg atgaaccaac agcacgaaat
     2041 caacactttt ggactgattg gaacccaagc ggcttatgag acgggtggag aatggttaag
     2101 ccaactgatt ccttatctag aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta
     2161 tcttccgaaa gtgagaataa tgaaccctga aggaacttac ttaatgtggt tagattttac
     2221 cgcctatatt tcagacgacc aagaattgga gaacactctt gttcggaaag gaaaagtcgt
     2281 attaaatcct ggcatcacgt ttggtccttc cggtcatggg catatgcgct tgaatattgc
     2341 ttgtccagaa gaaactttac tggaaggact taatcgaatc aagtatgctt tagagacaat
     2401 cgattaaatc atttattcaa aataaaagga cgagacctta ctaggtttcg tcctttttca
     2461 taattactcc gtaccatacc aaactattct gaaatttcaa ttgtttcaat cactacatca
     2521 tgtacaggtc ggtcttgtgg accacgttgt acatttgcga tttcatctac tgtgtccatc
     2581 ccttctagta catgtccaaa gactgtatgt cggaaatcta gccaaggagt tccgccacct
     2641 ttatacgctt caatgatttc tgatgggaat ccagcacctt ctagttgtcc aagcatatta
     2701 gctggcacat ttgtgttatt tacaataaag aattggcttc cgtttgtgtt tggacctgaa
     2761 tttgccatag ataaagctcc gcgaaggttg aacagttcac gactgaattc atcttcaaaa
     2821 ctttcgccat aaatactttc gccacccatt cctgttccag ttggatcgcc gccttggatc
     2881 atgaaatcag gaataacgcg gtgaaaaatc acgccatcat aataaccttt tttggaaagt
     2941 tcaatgaaat tttgaaccgt cttcggtgct agttcaggga ataattgaac agtaatgtca
     3001 ccacggtttg ttttgataac agcttttggt cctttttcac tttttaaatc tagttgtggg
     3061 aatgccatat tgtttcctcc taatatttgc atacttcata ataataataa cataatacct
     3121 aacctctcgt aaaaatacta gatttgtttt cttttatttt tcatcactag atacattcta
     3181 taacttaccg tttcgatttc gaattcaaac atttttgaga agcattctca attaaattct
     3241 gctatagtgt gaaaagggag gaatttttat ggaaatctat gacattacaa tcatcggtgc
     3301 aggtcctgta gggatgtttg ccgcttttta cgcaggaatg cgccaagcta aaacaaaaat
     3361 cattgacagt ctacctcaac ttggtggtca attagcaact ttgtatcccg aaaaatatat
     3421 ttacgatatt cctgggtatc cagcaataaa agcaagtgaa ttaatcgatc aattagaaaa
     3481 acaattaact acttttaacc atacattcca tttaaaagaa gaagttctct cgcttactcg
     3541 tgaagacgaa gttatcgaga ttactacaaa taaaggcatc cattattcca aagcagtcat
     3601 tttagcttta ggaaatggtt cattccagcc aagaaaattg aatttagata atgctgaatc
     3661 atttgaaaac cacggattgg attatttcgt gaatgatttg atgaagtatg ctggaaaaaa
     3721 agtcgctatt gctggaggtg gtgattctgc tatcgattgg acgttgatgt tagagcctat
     3781 tgcaagcgaa gtttacttga ttcatcgtcg cccggaattt cgtgcgcacg aacatagtgt
     3841 atcacgcttg aaatcttcat ctgtcaactt gcttactccc tatctcatcg atggattatc
     3901 aggcaataat ggggaactga cagatatccg gttaaaaaaa gtgaaaagtg acgagacgat
     3961 tgatttgatg attgattctc tgatcgtcaa ttatggattc tcttctaatt tagaacatct
     4021 ttcttcttgg ggacttgata gtaccagaaa tgccattact gtaaaatcag atatgtctac
     4081 ttctattcca ggcgtttatg cagctggtga catctgtacc tatgaaggaa aagtgaaact
     4141 gattgctact gggctcggtg aagcacctac tgcagtgaac aacgctttac actatattaa
     4201 tccaaaggaa cgaactcagc ctggtcacag cacaagctta tacgataaaa atcttcgtcc
     4261 tagttgattt tttatatctc tttgcatttc aagttaaacc cgaaagcagt ttcttgcatt
     4321 tttttcatgt tccgttaaca tgaaatagag aaagaaaaaa taaaggggga gcaataatat
     4381 ggtcgtcaaa actgagactt tagaagaaaa ggcaagagaa ctattgaagg aacgtggcgt
     4441 aactgtagaa gatatcgcac aacttgtcat gtttttacaa aaagactata tttctgattt
     4501 gactttggcg gattgtactg aaagtgtcaa cagcgtgcta acaaagcgtg aagtacataa
     4561 cgccattatc actggaatcc aattagatat attagcagaa aagaaaaaat tgatgagtcc
     4621 gttgcaacat attatcgaag atgacgaagg cctttacggt atcgatgaga tcctagcctt
     4681 gtcaatcgtg aatgtttacg gtacgatcgg ctttacgaat tatggttata tcgacaaggt
     4741 gaaacctggt attttaaaag aactaaacag ccacgatggc gttcatgtcc ataccttctt
     4801 agatgatatc gtcggagcga tcgccgctgc tgctgccagt cgattagcac acaaagaacc
     4861 agaaaaaaga agtcgcctta ctcaataatt caacaaaaaa agaaagaaaa cgtctattta
     4921 gacgagttct ttcttttttg tttgtttcaa gctatttttt cctaagaaaa gaaaaacagc
     4981 aaaaaataat tctaataata caaaaaataa gataaagcta tgcatgaaaa attcttctgg
     5041 aagtacattg atgattggat cagtaacggg atcgaataac cagtcatcgt tgttgaaaaa
     5101 cgtttcatga aaaaggataa aaaagcgatc aaatcctatc atcatgaaaa aaccgaaaac
     5161 aactggcagt aacatgccga tttgaaacgg acgaatcaac cgccaaagcc gatcattctt
     5221 ttgcaaatat ttgataaaca aaatactcgg gatcaaagtg atgaaaaaca cagcataatc
     5281 cactaaaaac aaaattttca cttcataaaa gtgatgggct ccgctagcag aaactgggaa
     5341 atctggcaag ctgaggatgg ttttgaaggg attattgaga taattcatta ggtgatcaaa
     5401 atttttcagt aacgtctctt gatctaaaga agtataatcc aaaatttgca aatgtccgat
     5461 atcaaatacg tatagtggtc gaaagttgat cgtcacacca actgccagac tgatcagtgt
     5521 cagaaatagg ctgaacaatc cagcatattc catccactgc catctcgaat ttttcatatt
     5581 agaagctcca ttcatccagt gattgtttca cataggtagc tgggataggc aacccaggta
     5641 catcttcttc ttttgtaaaa cctgataaaa cgagcaaagt atctatatta ttgcgtatcc
     5701 cagcttggat atctgtttca tagttatctc caaccatgat tacttcttct ttttgcagcc
     5761 ctaatacttc aacggcttta tccataatga tggcttctgg ttttccgatg tagatcggcg
     5821 gcgtttgggt tgctgtctct acaaaagaga tgactgaccc tgctccagga agaaggccgc
     5881 gttcagtagg tatattctta tctgggttcg ttccaatgaa agtagcacct ttttgaatag
     5941 caagtgttgc tttaactact ttttcatagg tcagataatt atctaagcct accactacat
     6001 agtcaggagc ctcttcttcc catgtaaatc cggcagctaa aatcaagtca atcaatcctg
     6061 cttctccgat aacatagact tttttccctt ttccatctgc tttcataaaa tcgattgttg
     6121 ccaaagtagc tgtgtagact gtctctggag ctacatgaat gtcaaactca tctgctagac
     6181 gattagctac tgtttctggt gacttagtcg tgttattggt aacaaacaag aaaggtaatt
     6241 ttcttttttg caattcttcc acaaatcgtt taccggccgg tatgggttgt gtcccacgat
     6301 aaatcgttcc gtctaaatca attaaatatc ctttatagtc cattcatcca ctactcttcc
     6361 ctttttctga tcgtaaatgc tgtttttgtt ttttctactt gtttaggttg ttcttgtttt
     6421 tttacttttt cagaggtttt tgctgactct gtttttcgat ttttaataac cggttttttg
     6481 cgattagatg cgactggtcc ttttttctca tcgatatacg cacgattatg gttttttttc
     6541 ttttttcggc gctgagttgt cttttctttt ttaccgccga ttctctcgat gacaaaatac
     6601 gcacaaccaa aattgcaata ttcgtaaaga tagtcttcca aggaatcgat tcgctgatct
     6661 ggatgcgccc gtcgattatc cgcttggaaa aatcctttta ggcgtagttg ttcataaccc
     6721 caatctccta cgatataatc atatcgggct agtacatcac tgtaacgttc tccaagcttt
     6781 tctgcattaa atccttcacg ataatcggac acaagccgat aatgtctttc acctatcaaa
     6841 aaattactgt catctaacag tgtcactagc tcgcctttga ctttttctgc tttaggctcc
     6901 tcaacgattt cttccaaagc agctgtcagt tcttcggtga ctgttgtttc ctgttcagct
     6961 gatgattttt tcttagcaat ttctgtttta tgctcaacgt tctgctgttc attttgtttt
     7021 gcagacatgc gttcaccacc tatctttttt attatacctt gtttttattt gattgggtag
     7081 tgagctttca agtaatctcc taccacactt cggataaatt cagggaacaa aaattcattt
     7141 tttccagcaa tctcaatcgt tggaaaaaat ggaacaaaca tcaaatgatc tacggtagta
     7201 aaagtataat ttttattcag atcgattggc ttgttcttcc aaaagacttg atggttaata
     7261 gaatcatatg tgattccatt atagaccatc tgcccaaaaa tcttaccgcg aaatcccatt
     7321 cccttcatag gatagttacg taaaaagtta cgattttttt ctatttctaa aactaagcgg
     7381 atcagatcat ttccacccaa tgtgacattt aacaagtgca tcggatgcgg caacgcagtg
     7441 tgaagctgat cctgattgac ccgccctttt ggaatttcag ttaaaaacag accactgttt
     7501 aatattgctg cttccgtctt tcctcgttct ttcaccgcct caaaggctac ttggataaac
     7561 gaatgctcat tgaagatatc tagactcaga gaaaatggca aatctgctac ttctttttct
     7621 tttaataatt catgcccacg ttctagataa ctatttattt cttgttcatc ttctgtaaaa
     7681 gctgtcattg tttcggtagg gatggctttg gctgaatgct taaggatttt tttctcttca
     7741 tcgatggtta aatggacttc accgacatac tgcccgtact ttccagcggc tgctatttgg
     7801 acatcattga ttacgtgacc ttctctgaat aaatgatggg tgtgcgatcc taaaataaca
     7861 tcaattgctg gtatttcttt tgcaatttgg aaatcatcct gaatcccgag atgactcatc
     7921 aaaactaaaa catccacttg tgaacgtaaa tcttcgacta attctggcaa aatatcataa
     7981 ggattccgta tgtcccagcc attcggatta taagtaagcg gaaatggagc agtaaatgca
     8041 attagtccga ttttcgtctg gtgtttcgtt gtaatgattt tatatggttt cgtccatgcc
     8101 ggtggctgga gcgtattttt atcgaataag ttatccagga tgatatcaaa ctcagcatga
     8161 tcgtataaat gattcaactc ttctttggaa tttcctacgc cttcattgtt tcctatcgtc
     8221 gctgcatcat aaccaacttc attcatcagc aagatatttt cctgtccatt cgttgcttct
     8281 gacaatggat gccaacgatc cacaaaatca cctagatcta ctgcaatcgt tgtcgttttt
     8341 tctttctttt cgttttctcg tttacgttga tccaaaaacc ttctgatcct tggccaattt
     8401 tctaaatgag aatgcagatc attcgtatgt aaaatcacta ttttttccat gtaccctctc
     8461 gcctctcttt atctttatca taccataggc agctttttct tccattgaaa caagctctat
     8521 ttcagagttt ttcctgcctt gaagcaaatt gtataagtac aatattcgat aaatcagtct
     8581 ggctaaaaaa tcaggaacat tcatttttac agtactataa aaataaaaaa aacagacccg
     8641 aaagtctgtt gtcgtttcat tataatcaga cacatggcgg aacctgctta gtgctgcttc
     8701 cttccagacc tgacacgctt cacaagccca ccattgtcct agcctttcgg caaagaatag
     8761 tataccttat ttttcattcg ttgaccagtc tttttttaat ttcttttttc gctggcggag
     8821 ctttcggaaa aagtcagtca aaatcatccc acattcgtct tctaaaatgc caccttctac
     8881 atatgcttgg tggttaaacc gctcgtcctc caaaagattc atcaaggtac cggctgttcc
     8941 gccttttgga tcatacgcgc cgaaataaac ttctgctaca cgagacaaaa tcatcgcgcc
     9001 gctgcacata ggacaaggct ctaaggtaac aaaaagtgca gcatcttcca agcgccagct
     9061 tcccactttt tcacaggctt ccttgattgc aagcatttct gcatgtgtag tagcatcttg
     9121 cgtggtttct ctaaggttat atcctcttcc aatcactttt ccatccaata caaccactgc
     9181 tccaatcgga acttcatgaa gcatttctgc tttctttgct tctgccaatg caaggcgcat
     9241 ccatttttct ttttctactg catcaagatt tgtatttacc aattaccctt ccctgccttt
     9301 gttttttctt gttttacttt agcatatgat aaaaaggctg taactaactt ttttttctat
     9361 ggtaaaataa atacaagagg tgaacaagat gaaaatggat aaattacttg ctctttaccc
     9421 acaagcacag aaaaaaaact ctccagcatc agaagcggat atcctttctt ttgcaattga
     9481 tgatgctttt atctggatca aacaagattc attatctcaa caagaaacca gccttttgaa
     9541 agcgttattc cctgtaatca acgatcaaaa aaaacaccca tggtatcact atctttttaa
     9601 agatgcttct tgtgttcaag aaaaaagctt tcgtttgatc cagcttcacg tcgaatcaaa
     9661 aggagaattc ttaaaaaaag aatggcaaga tactattttg gaattatttc gctattctgc
     9721 tgatttcttt ttttatacag acacagatgc gctcttagtc gaacaaataa accgtgatta
     9781 tcttgatgct actgaaatca acggtatttt tctatcttta gatgctgatt ttgatacgac
     9841 aacgtctgta ttcgttggtt ctttccattc acctggcacc gacctcgtcc ctttgtttgc
     9901 tgaagaaaga aaaatttttt taacagagca aaacaatctt tatactcaca gccgtacttt
     9961 ttctatgcaa gatgtggctt tacattacta tacaaaagat actgtaaaag atagtaagtt
    10021 gatcaaaagt tacatagaac tgatcaaaca aaatgaaatg gaagtgatca ttcaagaatt
    10081 atggaatgaa ttaggcaatg tcagctctgc tgcaaaaaca ctgtttcttc atcgtaatac
    10141 tctaaaatat cgaatcgaaa aatttcaaga acagtctggt ttcaatctaa aaaaagccaa
    10201 cgatttactg ttttgctatc ttttattgct tcatgaacat aattaaagat agattaaagg
    10261 ggttgtgaca ataattttgt cacaacccct tatttcgaat gaatagtgtt caaaagctag
    10321 tttctcttac atcatttttt caacaaaatg cattagccgg tcttttacat cttcggttga
    10381 atctttgatt gaatcaccat aaacagagat tttctttttt cctgatttga tttttgctaa
    10441 cattcccatc aaagaatcca agtcactatc tgaaagacca tctacgattt ctagtaattt
    10501 ttcatttcca tcaaatttgt catagacgaa tttttttact ttcgtccgag tagtcatatg
    10561 atggatcttt tccattactt ttcccgatac aacgactgct gtcgctacac tggcagcggc
    10621 tgctacgctt aatccgattg ttacttttgt tgatgttttc ataagtatca gctccttttt
    10681 atctatctcc atcatagcat agacaaaaaa ataaacgaac taatccactc agtgaaatct
    10741 caatccttta gggaaaaagt tctttactgt tccttttact tgtttcccaa atccgacagg
    10801 tatcttatct aatactagca aaacccatcc ttgattccca tcacgttgaa atgtttctcc
    10861 tgctgtgtaa gattgccatt ccttttgagt gatcggcaag caaggtatat tctctatctt
    10921 ttttgtagca agcgctaatg catagctagg ttcaaatcga ttctttttga aatctcctaa
    10981 atgcaaacct gtacgtacga cttttaaacc atcgagagaa ggggctaact caggaacttc
    11041 ccaaagatgg tcgttgaaca ctaaaagtct tccagtagct tcataatgaa aatcatttga
    11101 aaactccgtc cagagttttt cctgctcttt tgtcatttgc actttacttt tttttcgtgt
    11161 cttcttttct ttatgcatct gattttgtcc atgaaaagtc agctttgcaa caaaatgtcc
    11221 ttcaccctga tctttatgag gccatatacg tattgttttt tccaaaccag ctacgcttcc
    11281 ccattcagaa cgtcctgaac taacggattg agtcaaagga atctcctcaa tcgttactgg
    11341 ataattttct acaagccagc taatgatctc ttcattttct tctggtgcaa acgtacaagt
    11401 cgaataaatc agttgtcctt tattttttag catttttatt gctgaagaca aaatctcttg
    11461 ctgacgtttt tgacagtata gcggagattc ttctgtccac tcttttattg catttggatc
    11521 ttttcggaac attccttctc ctgaacaagg agcatcaacc acgatccgat caaaaaagcc
    11581 cgaaaaatga gggacaagtt ctgcgggtgc atgatttgtc actattgcgt tcgaaactcc
    11641 ccatcgttct atattttctg ataaaatctt cgcacgtttc ggaaagatct cattcgtcac
    11701 taataaccct ttccccttca tttgagcagc taattgggtt gatttaccac cgggagccgc
    11761 acacaaatcc aaaacttttt caccgggttt tgctgcagca gctgttccaa cgatcattgc
    11821 acttggttct tggctatatt catacccagc ttgatggagg aaagactttc cattgacagt
    11881 gccaagaaat ccctcattgc tgtagggagc gggttgtaat tcttcgctat ggtaagtttg
    11941 gaccatgtcc aatcctgccg gttttagtgg attccaccga aatccttttt tcacgcttcc
    12001 ttgttcaagc gcagaaaaaa aatcggatgc ttcttcgcct aaaagaagac gatatttttt
    12061 gataaattgc tgtggtaacg ttgtcgcttc ctccttcatt ccaatgtttc gttagacatt
    12121 ttacaatctt ttttacgaaa aataaaggtg gctgatctac tttttcatgt tgctgcctaa
    12181 ggtgactgtt cctttaagat attttccaag tattcatccg tcacctcgtt tttatcccaa
    12241 acagcgttca tcatttcaag aaaatcttga gaagaatcat ctgagcgcaa acttcccaat
    12301 gcattaagcc ataccaattc aagcgacttt tcttctttga tcttcgtgtg acctttgaca
    12361 tatgagaaaa atggccgctt aaatagcgaa tccatgtcta aatcagattt tgcaatgatt
    12421 tcacgaatac tttcatggat agaaaaaaaa tctttcaata agtagacaat gcttaaaaca
    12481 tcatcggaac tgcattcagc taagtagttt tcaaaataaa cagtgatttc ttctaatatc
    12541 ttctctttta acccgctgat tgatttgaaa tgtgtataaa tcgggtatgt agaacaaccg
    12601 cagaactctg ctaactctct tgcagtaatt gacttcattc catattcttc cacgtatacc
    12661 atacttttga acagcaaata ttctttacta taatttgtta ctctccccat cattcttacc
    12721 tccgtctctt ttcatctacc cataaataaa taacataaat aattctaaaa atattattga
    12781 taattatcaa aacatattta gttatatcca ttaaaaatca atttttccgc cttaaaaaca
    12841 agaatatctt gacaaaatac cctaggaaat aaacaataga ataaacaagg taacaaaaaa
    12901 attaaataac gttatataaa aaagaaggcg acactctgtg agaataacac agactgaaat
    12961 gactttccac tcacagtttt tgtctaacta tatacaaaaa cagaataaaa aggaggtatt
    13021 tatgctaatt gaagcaagaa aaaaagagtt acttgttcta caaatggtca ttcaaaaaaa
    13081 taattgttct ttacaagaat tatccaatga cttacatatt ccaaaacgga caatcaaaga
    13141 actgatccga aaaataaatg tatcactcaa gcaattttta ttgattgatg aatttattta
    13201 ttctaatcat aaaggagaga tccaaaccaa agaaaccgat caaactaaaa agttagctgt
    13261 tttttctaag ttaaaattat gctacctaaa agaatccaat cgttttaact atttgatgtt
    13321 actaatcaat tatccacaaa ctgctgtacc aaaaaaatat ttacttgaac aactttatat
    13381 atcgccctcc tatctcgaaa aactgacaaa acagctcaat cattccttaa aaaaattcca
    13441 tttacggatc ctatctgtaa aaaattgctg tactcttgaa ggaaatgagt tatctatccg
    13501 tctctatctt tacttttttc tttcagatac atttggaggt aacgattggc cattttcctc
    13561 acttgaatta aatgcactaa aaatgaacag tacagatgag caaatagaaa aaatttcaaa
    13621 acaagaaaaa aatatctact tgctgttaac tttattcata ttacgaaaca aacaacaggc
    13681 atattttcca aaaacttctt ctgaaatcac tgaattgatg gacttattgc agcatacaca
    13741 tgattattca gaatacttta cttctttttc agtgagtcgc ccttgtgaag agacagaaac
    13801 agagagagcc tactttaatt attttttcta ttgttttttt ccaaatcaaa tctcttttcg
    13861 acaaaaacag gagattggtt ttttattttc cacaagcaaa aaccttattt gtcgacaagt
    13921 cggtcaattg atgacttact taactcaaca gtttcctctc aaccatttag aaaataaaat
    13981 accaatttat ttttattttc ttgtgttggc agttgttttt ttcgaactgt tgggtgaatc
    14041 cagcagtagt ttttctacac tttgctttcc agaagccacg tccaatcatt ctagttcttt
    14101 tatacaggaa aagaaattaa gagaaaaaat cgatacaatt ttttcaaaaa atggggaaag
    14161 aaaccaaatc agtcaatacc ttagtcaatt gatccaacac ttactacaaa cagaaacgaa
    14221 agagcagtta ctcatccatt tgcagataac caaacagttt acaggaaatt atcatcttca
    14281 aagccatttg cagcagttat ttcgcaaaga tgctgttaaa attaccgcat attcagaaca
    14341 tgctgatttg atcattacag atcagcatga gaaaatttca gatgaaacgg agactttcta
    14401 tctggataca acgcacaata cagtgttatt tggcaagtta ataaaagcgg ttcatgaact
    14461 gtatatgaaa aaaggttatg agaacaaaac aaagaggatg tgacaaaatt cttgtcacat
    14521 cctcttattc caaataaatg gtattcaatc agctaactct cggtattagc tcagatcaaa
    14581 gcgctgattt cacaacttct ttattttaat ctcttcggtt gccgccgaac aataagatca
    14641 agcgcaacag ctgcaggaat gtcgaaagcg ctgctgcaac ataagtcagt gctgctgcaa
    14701 ataatacgtg tcttgccatc ggtacttctt cttccgtcag tagtccgcct tcactcaaaa
    14761 tttggattgc tcgccgagac gcgttaaatt cgactggtaa tgtcaccaat tggaaaagta
    14821 atgctaaaga aaaagcgaaa atcccgatat tgattaacgt agagttccag ctaagcaata
    14881 cacctaccat aatcaagggg aacgaaatca tcgaaccaaa gttagctgct ggaacaagtg
    14941 ctgcacgaat cttcaatggg acataacccg aagcatcttg taccgcatgt ccgcattcat
    15001 gagctgctac acctatcgca gcaactgaag tagactgtgc agttgcttga gacaaactca
    15061 acatcttatt acctgaattg tagttatctg tgagatctcc ggcaatttgt tgaacaccga
    15121 cattatttat ctgttgactt tgtaatatat attgtgctgc ttgtgtacca gtcacattgt
    15181 ttttgcttct cacttgatcg tattttcgga aagtactatt gacgtacgct gacgcaattc
    15241 cggaaataac taatccaaga atgaccaaaa gaaatgtcgg atctaaaaaa ccatacattc
    15301 cataaccata cattttcgtt tcactccttt tcgtttactt tattttatca ttagtagtag
    15361 gaaaagaatg tgaaaagacc ttgaatattc tttaattctt tttcacaaat tccgatttca
    15421 gtttcatcgg tccaaatcct tctaccttgc aatcgatatt atgatcgcct tctactaaac
    15481 ggatgttctt gacttttgtt ccttgtttaa tggcacctga cgcacctttt actttcaagt
    15541 ctttaatcac tgtcacgcta tcgccctcta acagacggtt tccatttgca tctaatacca
    15601 ctaatccgtc ttctatgaca gtttcttgtt cttctttgtt ccattcgttc ccgcattctg
    15661 ggcaaatcaa caagcctcga tcttcatatg tgtactctga gccacattct gggcaatttg
    15721 gtaatgtcat cttctttctc ctttaaaatc tttagtgagc actattgtaa cggaaaaaga
    15781 agatcttgaa aagatacatt tgtgattttt actacaaaag gcacgttttc gaacgaagta
    15841 tcattctgtt tttctgctct tatacgattg gcatatatct tggatctctt tatagatttc
    15901 ctctacttct gctaaatctt ttgcattcgc accacttgct aatggatggc ctcctccatg
    15961 atggcgttta gccaattcat tgatgatcgg ccccttagaa cgtaaacgta cgcggtaata
    16021 ccctgaaggc tgctgaacaa aaatccccca agccagcact tcgtcaatca ctccaggaag
    16081 tgaaacgatc gaagctgtct ctgaatcatc gattccatat ttatcaagaa tttcttgcgg
    16141 aaggattatt cttcctgcac cattttcatc cacctggata ttttgataaa gataaccgga
    16201 aagtttagcg actttcatcg gcatttgttc aatctctctg ttcaaagcac ttgcatcaaa
    16261 tggataattt ctcaatatcg aagcaatctc taatgtacgg gacgtcgtgg agggatacaa
    16321 aaagcgccct gtatctccga cgattcctgc ataaagtaac cgtgcagcct taacgttcat
    16381 ctttaaagat tcaggaaaca tcaaagcaaa ttctgcaatc atctcactac agctacttgc
    16441 ttttgtattt acccacacaa gatctccata agggtcatca ttgggatgat ggtcgatttt
    16501 gatcagtttt tctgccaact gatatctttg atcactgatt ctgggtgaat tagctgtatc
    16561 agtcacgatg actagcgctc cttggtagaa gacatcttca acttcttgca tttctgctaa
    16621 aaagcgaagc ccttcaatcg tttcacctac ttgacgtatt tctttttctg ggaaactttc
    16681 ccgtaatagt tcggctaatc ctacttgtga tcctaatgca tcaggatcag ggcgcaaatg
    16741 cctgtggata atgattttat cgtatttttt tattgtatct actatttctt gctgtactgt
    16801 catttcactc ctgctttcta agaacgttcc attacttgac aaacaacgat tgctttggaa
    16861 acgatggtgt tttcaataaa cacttcgata tccagtttag cggaacgtct gccgatttcc
    16921 aatacacgtg gacgaatgtc taattcgctt tccaattgga tcagccgcaa ataatgtagg
    16981 ttcacttgtt caatcaagat atttcgtttt tggttcatca ccattgtttt ttgtgcgaca
    17041 tcagaaatga tttcgctaag tacgccaaaa gaaatggttc caacgccatt gaccatttgt
    17101 ggtgctacta cgaatttgaa cttagggttt tccaaacgat ttccttcacg gtcagtatca
    17161 atcgtatgga tatttccaga tatctgatcc gaaatcgtat ctgcaatctg cggttgtcgc
    17221 tggacaagct gcatcgcttt cattacatct tgccgggtaa tcaagccttc caatgtcaag
    17281 tcatcggaaa cgaccggcat gacttctagc ccatcccaga tcatttgatg gctaacagag
    17341 gcaatactca ttgttttctt tacactgatt ggttctttcg tcatcacccg atcgatgatc
    17401 tggtttggcg atttccctaa aacatctttt gccgtaacaa tccccatcaa acgatgatgg
    17461 cggttgacga ctggaaaacg cgaatgctgc gtttcttctg acaaacgctg ataatcagaa
    17521 atcgtatctg tctgctgcaa ataatgagtc ttttcagctg gcatatagat atcactgaca
    17581 agcatgatat cttttttgat caattggtcg cttaacgctc ggttgatcat ggttgcgact
    17641 gtaaatgtat cataagaggt gcgtaagatc ggcatttcaa gatcatcagc tagctttgca
    17701 atctcagcag tcgtattgaa tcctcctgtg atcaatactg cggcgccatc ttccaatgct
    17761 aatttttgga cttccgcccg gttgccgacg atcattagtg atcctggcgt aatatagcgt
    17821 tccatggcat gtttagtcat cgcgccgatg acgaatttat tcaagacctt gtctaatcct
    17881 gccgccccgc ctaaaacgtc cccttcaatg atcctgacga cctcgccaaa tgtcaaacgt
    17941 tcaatatgtt tttttaattt gcgttcgata cggatggtcc ctactcgttg aattgttgaa
    18001 actagtccga cattttctgc atctttgatt gcacggtacg ctgttccttc actgacattc
    18061 aattcttttg cgatgcttct tacagaaatt cgattgccaa caggtaaact ttcaatatat
    18121 tctaaaatca aatcatgttt tgtcgccatt ttctgcctac acttccagcg tttccgagac
    18181 gctcattatt tttccttcac tatcttccag taactctaca aaagattcgg gatcttgttc
    18241 aatgacaggg aaagtattgt aatggattgg aactactttc ttggcacgaa ttgtttgcgc
    18301 agcctttgct gcatcttctg gccccatcgt atagttatcg ccaatcggca agaaagcgac
    18361 atcaatatcg aattcttctg caagcaatcc tagatcactg aaataagcag tatcccctgc
    18421 atgataaatc gtttttcctt ctgcttgaat aataattccg ctaggctcgc ccatatactg
    18481 aacgataccg tctacttcat agcttgaact atgctgtgca tgtacgaatt ttaccacgcc
    18541 gaatggaaac gcatgttttc caccgatatt cataccgaat gaatctactc ctctgctgtt
    18601 cgcataatca gcaatctcaa caatactgat aattgtggct tgattttctt ttgcaatagg
    18661 aatcatatct cctatgtggt cactatgacc atgagtaatc agcaaccaat ctgtctttac
    18721 ttcttctgca gttaagtctg tcaatggatt tcctgtaata aacgggtcaa tcatcacgcg
    18781 ttggccattt tccatttcaa ttgttaaaca ggaatgtcca tgatacgtaa ttttcatatt
    18841 ttacacctcg cgttttctct gtatcttttt tattaaaaac gatttcatca cttgcacatc
    18901 aatgaaaaaa tatagctgct aaatatattt tcattggatt gatagtacag tatgtacaaa
    18961 gcaattgtaa cagataatac aggatgcacc aagtaccaag cagatataat ctcaagtttg
    19021 aggtctctgc tctgcttagc ttctcttctc gtcccttaac taattaaatc agcgtaaata
    19081 ggatggacga tcttttctaa atcggctact tttatccgaa ggcttctccc gatttcaccg
    19141 cttgacacaa ttacttcttc tttttctttt aaagaactgt ctgctaaaaa acaataatca
    19201 ggatgtgcga gttttattcc aataggggtg tttgctccgt ggggatatcc tgtatgcatt
    19261 aatacaaaat ccattccagg aaaaccaact ttacgatctt tcgtcacttg tctcgttttt
    19321 ttgtaatcta agtgatcgtt caaaggaatc aatgcgatga tcaccccagt tttgtttcct
    19381 ttcactacga gagttttaca tatcaaagct ggatcaatcc ctcttttttg tagttcttct
    19441 gtgaaagatt cttctaccac atgactaaaa tcaagtggtt gatagctgat cttttgttct
    19501 tctaaataac gttcgacttt tgtttgactc atcattgatt cactcccttt attctatcgt
    19561 ttattataaa gcgagggatg ctgtattcaa aaattatttg tttttcgcaa aaaaagagca
    19621 agacgagcac tctatagaga ggttcatctt actctttttg tttatttttt atttcgacgt
    19681 tgagtagctt ccataatgac tggcaagatc actgggcggc gttttgtttg ttcaaataag
    19741 taacggccta attgatctcg gatgtcttgc tttaatttgc tccactcaaa atcattgctt
    19801 tctaaatgtt tctcaacgat tgtttcaatc atattgctgc tttctttcat cagatcacgg
    19861 ctagctttta cgtaaacgaa tccccgtgaa gtaatttgag gttttgaaat gattttcttt
    19921 tctcgccgac tgatagtgac aaccgctacg aaaatcccgt cttctgacaa gatttttcga
    19981 tcacgtaaaa caatgtttcc gatatcacct atgcctaatc catcaatcat tacattttct
    20041 gcacttgtag ttcctgcaac actcatacgc ttgttcttat attccagcac gtctccgcgt
    20101 ccagtaatat agatattttt gtatggcatc cctactgcat gagccaaatc tgcatgagca
    20161 gctaattcac gatactctcc ttgaactggc acaaaatatg ttggtttcat caaattgatc
    20221 attaattgca agtcattagg attggcatgg ccagaaacgc gcatattctc agagatcaac
    20281 ttcactgttc caccagctcg ataaatgata tcttccgttt tcgccacgat ggtttccatc
    20341 gcgatgcttg gcgtagtagt gatataaacc aaatctcctt cttcaatctt gacattacgg
    20401 tgtgtaccgt ttgccatttt ttgcagagac ttgatgggtt cacccattcg gccagtttct
    20461 aaaatgatca gttcttctgg atcatagttt ttcatgtctt tcaacgtaac aagcagatct
    20521 tcacttggta attgaagttt ttctaaacgc atcgctgtgc gaataattcg ttcgaaatct
    20581 tgaccagtca agacaacttt tcgttgtgct ttttctgctg catccaatac ttgttgcact
    20641 cgttgcaaat tacttgctac acaagcgacg atgatacgcc cttcccaata tttgatcgta
    20701 tcaaatactt catctgctat ttgggcttca gaagctacag gctgaggatt ttctgcattt
    20761 gccgattcac ttagtaaggc taagactcct tctttgccga tttccgccaa tcgtgcataa
    20821 tctgtttgat acattgggat agccgtttgg tcaaatttaa aatctcccgt ataaacgata
    20881 ctaccttctt ttgttttcag attgatcccc actgaatctg gtatcgtatg agtggtacgg
    20941 aaaaagctca ctactgtttc accaaagtct atttctgtat gctcatctac cacatggaaa
    21001 tccttaaatc ctttggctgc ttcattacga ctgacattca attttgctaa ctcgatcgtc
    21061 aactctgtcc cgaatactgg tacagaaatt tttgacaaca agtaaggaag tgccccgatc
    21121 gcatctgcat gtccatgtgt taaaaagaca ccagctacac gatcaatgtt ttcttctaaa
    21181 tacgtaaaat cagggattac gacgtcgatc cccaacaact cattttcagg atattttagc
    21241 ccacaatcta aaataaaaat atcctcgccc acttctgcga catacatgtt ttttccattt
    21301 tcacgaacgc cgcctaatgg gataatttta atggtactca caaacttcac ctcttcttat
    21361 gacatccaag tttaaagatg tcgattttct tctttatcta aatatatgag ccattccaat
    21421 gaagcatatg caaaatcact atttctcaac ttatggagaa tcagcaggaa aattaccagc
    21481 acatccgcgt tctgacagtt ggatgggcat tttattttgg atatacttca ttaacaaaat
    21541 ggatcttttg cgaaacgcta tagccagaat acttatataa gtattcagct gttccccatt
    21601 attatacaac aaataaacta aatcgctagt atcagcaatt gttagaacaa ctatgcacgt
    21661 aaaaatccct ctgtagcatc taggatttct tttgctattc ctctttcatt tcttcttcgt
    21721 cggtttgaaa catacttttt tcattttacc acattttttg caataactat agtgactttt
    21781 tatatataca gaacctcatg ttgatggtgt gcaaacagca taagatttaa gctagcttta
    21841 agataggttg tctattatca aatgcatcta ctaggaggga tgcaaaatat gaattttatg
    21901 aaacgtgcat ggaaaagtac aaaagtaaaa tggggacgtt cattgttatt gtttgccgtg
    21961 ttcacagcca ttcttatttt tgtgctagct ggcctcacga ttcgaagcgc tgcagaagaa
    22021 gcagcgaatc aagcacaaaa agaagttgga gcaacagtga ctttaagtgc caatcgagaa
    22081 gcttcattta aaaaacagga acaaacttct tcaagcggtt ctaccactga agaacgtcca
    22141 gatccaggca gtttttctct tacaccagtt tccttaacgg acgcggaaaa aatagctgaa
    22201 ttagataatg taaagagtta ttcctttgaa agttccgcct cagctatggc aaaagatgga
    22261 ataactgcca tcactagttc tgattcaagt gaagacagtt cagaaactac tgatgcaggc
    22321 ggtgaacctg ctggaggaat gggcgggaat ccgcaaatga ctcaagcaga ctttcaaatc
    22381 agtggtgtgt cagcaactgc acaaaatagt aatttttctg atggaacagc aaaaatcacg
    22441 gatggtgaag gaatagatga cagcgacaaa ggcacaaaca atgtagtcat tgattctact
    22501 ctagcagaaa caaatgacct ggcagtcgga gatactttca caatcacgag tactgaagat
    22561 gaagatacca cttatgaaat gacgatcaaa ggaatttatg aatccagcga aacaagcggc
    22621 agtatgggta tgaaattcaa cttcatgaat ccgtcgaata cactttacac ttcttacact
    22681 tttgcaaatg aactaaatgg gacatctgac gataacacga tagattctgc tatttacact
    22741 ctatctgatc cagataaaat ggatgagttt ctcaaagaag ctgagaagct gatcgacaca
    22801 gatacattta gcttacaatc aaatgattcc atgtatcagt caatgttgga acctttaaac
    22861 aacgtggcaa gtttttctaa aaatgttgtt ttactagtgg ctgtagccgg tattatcata
    22921 cttactctga tcattatgat taccattcgg gagcgtcggc atgagttagg cgtcttgcta
    22981 tctttaggag aatccagaag taaaatcatt ctccaattgt ttaccgaagt ggctatttgt
    23041 atgattcttg cattaggagt tgcttcgctt agcggaaacg tcgtcgcgaa tgccgtggga
    23101 cagcagctac ttgaccaaca gacagaaacc acgacacaaa accagcaagc tcctggcggt
    23161 ggacaaatgc caggtaacag acaagaacaa ggcggtcaac gcgatggtca acaaggaacc
    23221 acgaataatc catttgctgt ttctgatcaa gtcagcgaat tggaaatcaa tgtcaaacct
    23281 gcacaattgg gactattagc cggagtagca tttggaatca gtctgttttc tgtcttttta
    23341 gcttctatag ggatattaag attaaaccca agaaaaatcc tattaaacta aaggaggaat
    23401 ttgatgttac ggacagaaca attgggattt tggtatcaag atccgcaaga tgcgctttat
    23461 aaagatgtag aactgaattt cgaagctgga aaaatgtacg ctattttagg agcaagtggt
    23521 tctggaaaaa cgacttttct ttcgcttatt tctggactag atgcaccaaa agaaggaaag
    23581 gtatactatc aagatcgttc actgaacaaa atcgggttaa gaagttatcg taaaaatgat
    23641 gtctcgatta ttttccaagc ttacaacttg cttccttatt tatcggctct agacaacgtc
    23701 atagcagcaa tggaaatcac taagaccaag caagagaatt atcgacaagt tgctttagat
    23761 cgactggctc gtgtaggaat tgatgaaata ttagcaaaaa aacaggtgac caaactttcg
    23821 ggaggtcagc agcagcgagt cgctatcgtt cgtgctatct gctgtgaaca tcaactaatc
    23881 gtagcggatg agcctactgg aaatctagat gaaacaactt cacaagatat cgtcaaactt
    23941 ttccaagaaa tcgcccatga acaaaatcgc tgtattatca tcgtgactca tgagattgaa
    24001 gtagcaaaaa gctgtgatga agtctttgaa ctaaaaaata aaaaatttca aaaaatcgaa
    24061 gtttaaaaaa caggataatg atcaaataaa aaatccgaac catatctgtc tcgcagatat
    24121 ggttcggatt ttttatttgc ttgattcaat tagtaataag tggtttttat tttttttcgt
    24181 cttttcgaga aaacttgtct ttgacttcgt cgcctaaatt tcgagctttt tctttgatgt
    24241 cagcacctag tgattgtgct ttcccttctg tttctttgct cttgtcgtct gttgctttgc
    24301 cgtatgcttc ttttccttca ccgactactt tatctttcat atctttagaa cgtcctttta
    24361 aatctgccat tgtgcttcct cctcttagtt tgtttattga tctaccttca gggtaacatc
    24421 aacaacagat acagacaaac agaacgctcg ttttctaaaa aagatagtta gagctgttga
    24481 ttaaaaactt ttttcgaaag tcccccatac tttgacttct ttttcttgga ccattatttc
    24541 tcctttagcg ataactgtat caatatcaag cgtttcttta tccaagatac acagatctgc
    24601 atcagcacca atttcgattt ttcctttttt atccaatttc aatatacgtg ctggattact
    24661 ggttatagct cgtaaggcga tttccaaagg gatactttct ttttgcacag cttctttgat
    24721 ccctactagc aatgccttgg cacttcctac tcctaaccct aggaaatgat tgttttcatc
    24781 aaaataaggc aagcttcctt gtccatctga ggtcatcgtg aaattatcta aagaaacatc
    24841 ttcctcgatc aatcgtttca gtgctttgct gaagcgaact tcaccatctg tcttctccca
    24901 aaaatcagga tcttcgctag cagtgaagtc aatcgtgcca ccacgtttgg caaatgccac
    24961 gcaagcttca aataattctg gtgtgcgatt tgcatgagta ggcaaaaatt gtgtgatcgg
    25021 aatttctgtt tcttctacga ttcgtgtcaa tagctctagc tttctttttc ctccgcctaa
    25081 gtggacattg atgatcccag cttttccgga taacatgcct cctacacgag catctgctac
    25141 tgcacgagcg aactcttcaa aacttggctg agaagaacgg tgatcggata ctgcgatttc
    25201 tccgattccg ataattttat caattgtcaa aaagtctttg atgatagaat ctgttactgt
    25261 ttttaccggc aatcggtacg aaccttcgta tacataagtg gagattcctt ctgcttccag
    25321 acctttcgct ttgctgatca acgcagtcat atctctacct tctccgtctg ttcccaaaca
    25381 accgacaact gtcgttacac cagctgtagt caattggctc aatgtgactt ctggcgttcg
    25441 attttgataa ccgccttctc ctcctccacc taaaatatgg aaatgacagt caatgaaacc
    25501 cggggttagt acttttccct cacctgaaag ttcttctact tccactcctt cgtagccgcc
    25561 ttctagctgt tcttctacag ccaaaatctt cccaccggca atcagtacat ccatttttcc
    25621 taagtaatct ggtgcaaaca cttcaatttg tcgaatgatt ttcatacatt tttcctcttt
    25681 ctttaagtat aactgatgat aggatcttaa aaaataatcc aaacgatagg atctttactc
    25741 ctttgatttt accgtaaaat gacggttctt ggagtcctta tctactgttt ggattacttt
    25801 tttatttaca ggtctccagt actactgcag acctattgca atggcaatca tgatgaaaat
    25861 agttcctaaa acaaacagga atccttgcat cttgatttgg aatcttgccc attttgccca
    25921 ttcgatccgt gcaacaccta gcacaccaat caagctggct gatacgggtg taaaagcgtc
    25981 cataaaacct gaaccaagct gataagcaag aactgctact tgtctggata cacctactaa
    26041 atctgccagt ggagccatga ttggcatagt caaagctgct tgtcctgaat ttgatgtaac
    26101 aaccaagttg aacaaacttt ggaagatgta catcgcccaa gcaccaatga cagctggaac
    26161 accggtcaac gccgtcccga tcccatgcaa aatcgtattc aaagctgaag gaacagatgc
    26221 atcagatcct cccaagacaa gaagaatccc tttggccata cctactacga ttgctgtacc
    26281 agctaaatca gctgcaccag attggaaaga agaagcgatg tcattgactt tcattccatc
    26341 taatttgaaa agaacagcaa tgattccagc aactaatccc atcacaaaga attgagaagc
    26401 gatttctgga atgtaatagc ctttttgagt cacgccccaa acgatccaga caaggacaac
    26461 taacatctct aataagatca atttatgccc aagcatgaat tttttatttt catcagatgt
    26521 ctttttgata tgagaacgga aataatcatc tgatttgtaa gtcaacgaac tttctggttt
    26581 tttacggatt ttttctgcat atatcatcat ataaccagcg gctaatgcag taacaactac
    26641 ccacataatc aatcggaatg tcgcaccaga caacacgggg attccagcaa tcccttgagc
    26701 caccgctacg ctaaacgggc tcatccaaga ggtcgcattt ccgacttgag atgcgacata
    26761 agtcacggtt actgctacga tcgagtcata tcctaacgca atgacaaatg gaaccatcac
    26821 cattgagaat ggaattacct cttctgccat cccgaatgta gcgccaccga atgaaaaagc
    26881 aaagaataat agcggtaaag ctaaacgctc cagtccctta gttttactga taaacgcata
    26941 gatacctgcg tcgatcgctc cggtacgcat aataatacca aaagcacctc caacaacaag
    27001 gatcaatgca gcgatcccta cagcagatcc atacttatct ccagatacta gtccttcaaa
    27061 aacaaaattt aagaaaccaa agccgccaaa atcatctgtt ccccatattt tggctgtttt
    27121 atgcaatttt ttagaagtat catagatatt ttcgccgtac tgatcgtaaa gcacatcatc
    27181 tgtcaaggag atttcatcta gtttttcctg cgtaagattt ttttctccgt cagcaatgac
    27241 tttttccaat cctttttccg gaacatccag tttttcacgt tctgctggat gatcttgcag
    27301 ttcttctaat tgatcaaaca catacgactt atccagctcg taagcataac ggaaggaatc
    27361 ttgacgtaaa acagtacgag tacttgtttc gccatttgca tctttgtatt caatatcttg
    27421 cgtgctgaac tttcctgctg gaacgacaaa agtcagtatc catgcaaaga tgactacacc
    27481 aaaaataatg acatacgtat ggggtgtcga taatttagtg aagtcgcgtt tcggttttcc
    27541 tgaagaattt gttttcttca aatttatttc ttcctttctt ttttcagtaa ttttgatgaa
    27601 taaaaaatgg ataatcaaat gaattataca gtaaaaatga catttccaca tgaataattt
    27661 attagaaaat cacttttttc tattttgttt tttttctcct atgtatgatt atttttttct
    27721 ctttccattt atattaagta ttttatttct ctgtttttcc ttaaaattct ttttttattt
    27781 ttagattaga gaaaatctcg tcctgttttt ttcattttac aatcattgaa aaattgaatt
    27841 tcattgcaaa aaaaataata aacacttata aatatccatt atctatcctt caatttttgt
    27901 gtattttatt tctattagaa aaaggtatcc tgttggacaa ttttgttata tcaggtaaac
    27961 ttcattgcaa taatgataac aaatgtacta taattacttt gtaaagagtt ttggggaaga
    28021 ctctttcatc aacgtgtatt aagagacaag aaagaatcca tatggattct ttcttgtctc
    28081 tttttccact actttttatt tttctgacac tacatattct tataactcat ttctcataac
    28141 tgtgaaacaa cttataaaaa taacaaactt taaacaaaac aagcttaaaa tcaaagatga
    28201 tccatcttaa aataactaaa acaaaaaaag tagtcgttgt taatcctcat taataatcgt
    28261 tttctttttt tcaaacgctc catttttatg tggaacatta tttttttaag gaactttgtc
    28321 aacatgtgga taactatttt ccacttgtgt cctggactag ctgttttgct gtaaaataca
    28381 aaacttgctg cagcaaaaag atcgttgcaa gagaggctgt tccgcagatc gctggatcta
    28441 gatttggcaa agtcaagact gcatcatgta aattggcgtg gttgtccaaa accaaatcag
    28501 caaattcaaa taatcgcaaa ccactgctat gttgcgattt gatacttcgt gacaaatcaa
    28561 atccagtaac aatgattaat ggatgaccat tttctttgat ccactgagct agttcgatga
    28621 ttgccgggtt tcttccttca ttcgaaagaa gaagaaaaat gtcttctgat ttgacagaaa
    28681 gctgatcaat aattgcctgt cctgcacctt ctagcgtttc atagacacct ccggctggat
    28741 tttcaatcaa tatacttggt acaagatccg gggtttgatc ccaaaattca aatgctacac
    28801 cacttagtgt gcggctagca tatatctgca atctaccacc ttgattaatt tgtttcgcga
    28861 tccaagtgcc agcttgaagc atcagcggct cttctatcct taatttctct tccaattggt
    28921 gataatagtc aaaataacat aaactcattt atctctcccg cctagctata cttgacatga
    28981 atagaaacag ctgcctaatc taaggaagta cataaaaaaa cagtagttag acagtaacac
    29041 atgtggtctt tgctgtttca aacacaaaaa aggcattgaa cgaatacgcc caataccttg
    29101 acatagcaaa taaaacaacg tgcagaccat ggaaaatatc tacatagggg tagaattttc
    29161 accctagatt aggtacaata aattaggtcg atgcactgca ttgactatgg caaaatgatc
    29221 ggtcagggtg tatgtgtgtg actggtcatt ccctgattct tagcgccaac taagggtcag
    29281 ggagcctttt tttattcagc tgtttctatc tgaatttatt gtaagtaatc tcttatccaa
    29341 gtgcaagcaa gaaaatacaa aaaaacattg gtatgattta tatatatata aataacataa
    29401 aaaaaggaat ggcttatccc gatacaacaa gcattccttt aaaaaagatt cttttatata
    29461 agtgaaaaaa gcttttttcc accaattaaa taaatctctc atctcaatag tttatccatt
    29521 attttatctt tttttgcgta tacctactaa atattaccgt cttcttctcg ttcttctact
    29581 ttgttcgaga gaatctgtac tagaaaaagt agttgtatgt ctaccttttc tgcctatccg
    29641 agactttctt ttcatatatg ggatataaat gattagatac agtacagcaa aaaataaagc
    29701 aaatacgcaa gcttcccaac tacctaacgc caattcaacc atcaaggtag caaccccaac
    29761 ggatgctgca taccagataa aaatcagaaa cgtttctttt tttctgacca tgcgaaacat
    29821 gataaataga ctaataagca atagtggcaa cacaaatatc caattgcttc cttccatcag
    29881 ccacttgagt atatcaagca gcgactgtgc aacagcgact aattttccca tagtgaacac
    29941 acaccttttt ttataattaa aaaattcgct tttttattct actatgaatc ttctggcttg
    30001 gctttcattt ctcttatgta atcattttct tttatacaac ttaaaaaaaa attaaaccat
    30061 tagcataata ttttctgaat ctattcacga aagtcttttt ctatctttcg ttttccacga
    30121 ctcaactgat ctagagtcaa aaaactaaaa cgacagttgc gcaaatgacg cacaagctgc
    30181 cgctttaata acaaatagcc tttcattctc agcaggccac ttatttccag ttaactttct
    30241 gttcttagct ttttactcaa ctggataata tatgcactta atgaagtccc aatttccgaa
    30301 tgttgaagtc catattcaat atttgtcttc atatatccta acttatcgcc tacgtcgtat
    30361 ctttttcctt taaactctct cgcatagacc gcctctgtct ggttaagagt ctgaagtgca
    30421 tccgttagct gtatctcgtt tcctgctcct ggttcttgag tttctaatat ctcaaatatt
    30481 ttaggagtca gtagataacg tccgataatg gctaaattac ttggtgcttt tcccatttca
    30541 ggtttttcta caaacccttt tactctgcaa cgaccctttt cgctatctgt tttaggatca
    30601 ataattccgt atttagatgt ttcattttct ggtacacgca tgacggcaac agcggaagct
    30661 tgtgtttctt cataatccat catcaattgt tgagtcaatg ggatatcatc tttcatcaaa
    30721 tcatccccca gcatgacgac aaacggttca tttcctataa atgcttttgc ttgaagcacg
    30781 gcatccccca gtcctcttgg atgagattga cggatgaagt gaagattgac ttgagtcgtt
    30841 tcttcaacta aagcgagtaa ttctgttttt tccttttccc gcaaattgtt ttccaattcg
    30901 atatttgcat caaagtgatc ttcaatgggt cttttttctt ttcccgttac gatcaagatg
    30961 tcttcgattc ccgaatccaa tgcttcttcc acaataaact ggatcgttgg tttatccacg
    31021 attggaagca tttcttttgc catggctttt gttgccggca aaaaacgtgt tcctagccca
    31081 gcggcaggaa tgactgcttt tttgaccttc acttgct
//
LOCUS       DAYYEF010000032        29694 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000032 DAYYEF010000000
VERSION     DAYYEF010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.032"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1817)
                     /locus_tag="ACHA1B_001634"
     CDS             complement(<1..1817)
                     /locus_tag="ACHA1B_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFM8702401.1"
                     /translation="MKIVKEKIASRKIHWLALSILVLMFIVVFTGNVVQASIFNWFDD
                     TESQTEFLNNPVYQSYLKKYNGNFYSQFGLWIGWSVIKSMFAIVDGIQNMIPEVLDLF
                     SFIESTGMNKVYQSVLSTVVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSVALI
                     LLMPTLIGSTEKLSGIMFAKTLYNDATSINNQDGGVAWSLIEQGVTDLAYINKTDQYS
                     TIDKTNDRNNLTKENFWKTDLTQVLTDNVIDKMEKENPTADNLRYELVENSDNEFVAT
                     KFSDNFLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRV
                     LGVLVFATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFINYLNTGEGISANIF
                     IKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRS
                     KGGKNNGGNDQAEGEERKPERNFGQSLSKKANKTGKALGYAHERGLSGLASDGSTMAS
                     ERATKPFKSMRDIANDTKSKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPT
                     RLSDRKDGAKVENADSIMSSSERMREAMKNNAESNNNPV"
     gene            complement(1804..2022)
                     /locus_tag="ACHA1B_001635"
     CDS             complement(1804..2022)
                     /locus_tag="ACHA1B_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702402.1"
                     /translation="MIENRLIDQVWCLDQNTDNLELIETICFNTIVLDLRSENDNCVT
                     HIIIDRKTAQKLSESLRKWAEGGNNENS"
     gene            complement(2098..3111)
                     /locus_tag="ACHA1B_001636"
     CDS             complement(2098..3111)
                     /locus_tag="ACHA1B_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFM8702403.1"
                     /translation="MEEIDKLIAQYAYSKDDVYAEKYLKYPIFLDKHKKYKKMKQSTK
                     KVYMYLKKQNEYSLENSKVDSKGRIFLIFAIEKIAEKSCLTKKTVISALRELEEYKLI
                     TIKKNGFNKKTGKNNPNFYYLLKPEFSEGDFYKKKCIEENLHLPTNQHYSPSEKNTPS
                     DKSTFDGDKSFPLPGEKFLQELNHSSKDFKDFKESQNADFIDSLSVENKKLDEILIES
                     LIEKEWLYQVWGDNIVNCLKLVGNNDYSQFYDWYKKFKYAIKSAEKEQKIQLKIIYEI
                     CNNKYFVDYVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNKALELIELQISEGI
                     DKQ"
     gene            complement(3315..3596)
                     /locus_tag="ACHA1B_001637"
     CDS             complement(3315..3596)
                     /locus_tag="ACHA1B_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702404.1"
                     /translation="MKSEIQVILPSDLDQELRRYFYRVAKEAVDQVRIETSLSKEVFR
                     LGEACKYLSCSRSTLKKFIREKGLKVSIIGDCQFIRKEELARFIKEYEV"
     gene            complement(3647..3853)
                     /locus_tag="ACHA1B_001638"
     CDS             complement(3647..3853)
                     /locus_tag="ACHA1B_001638"
                     /inference="COORDINATES: protein motif:HMM:NF013540.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8702405.1"
                     /translation="MKPKDFRKFCGLSQSELAEKYGISVQAVRNKESGKTNYSPEEMI
                     ILKYLVKEKGIENITIDQIFFNEK"
     gene            4017..4748
                     /locus_tag="ACHA1B_001639"
     CDS             4017..4748
                     /locus_tag="ACHA1B_001639"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8702406.1"
                     /translation="MFDKNINSEIGKRIQEIRVSLGYTLEEFGENLTPPASKSNVSRW
                     EKGKNIPNKARLLSIAKLGGVSTEYLLTGNSQKTKKYIKYLFNEIFFDNGTFHNKFKD
                     FGKDRDRLGLYDLFLAVSKTYSLDKSPSLKDNFVEMIIDDVYKKLLQTDKSDDQLILG
                     FIYICLDEKLSNRQKSLKSINYEVFNYLGVAFGLIDSEIKSTNAGNDEDLLNYLKELT
                     SFIDEIKTTTFNKKKYFQNQYDIEE"
     gene            4802..5947
                     /locus_tag="ACHA1B_001640"
     CDS             4802..5947
                     /locus_tag="ACHA1B_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8702407.1"
                     /translation="MATIKQYEKKDGTKAWMFQTYLGISPLTGKEVRTTRRNFKTKKE
                     AQIELNRLLVDFEENGLKRETNETFQEVYDLWYESYKTTVKEVTQLKIEIKFNKWILP
                     KYGQFRIKEITTKHVQKILNQWAKTTDQYKVLHSTVSRIFKYAMTLGLITKNPCELVI
                     MPNRNVEKKKDTVKIYSRDQLETLFQYLESKRSTYRAEYDKTLLRFLFFSGCRISEAL
                     ALDWSDIDFDSNTVTINKTLSQTKYGYKISSPKTRNSYGSLSLDNKTINWLKKWQINQ
                     KRYMLTLGITDPTMIFCGIYKEIITKHAIYSRMITICKNSGIPFLGNHVTRHTHASML
                     LESGVSMKEVQERLRHSSIKLTMDTYAHLTKETKEKTVEKLAEHLNF"
     gene            complement(6032..6337)
                     /locus_tag="ACHA1B_001641"
     CDS             complement(6032..6337)
                     /locus_tag="ACHA1B_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HFM8702408.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(6362..6793)
                     /gene="ruvX"
                     /locus_tag="ACHA1B_001642"
     CDS             complement(6362..6793)
                     /gene="ruvX"
                     /locus_tag="ACHA1B_001642"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HFM8702409.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(6790..7056)
                     /locus_tag="ACHA1B_001643"
     CDS             complement(6790..7056)
                     /locus_tag="ACHA1B_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HFM8702410.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(7311..8036)
                     /locus_tag="ACHA1B_001644"
     CDS             complement(7311..8036)
                     /locus_tag="ACHA1B_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HFM8702411.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(8397..8467)
                     /locus_tag="ACHA1B_001645"
     tRNA            complement(8397..8467)
                     /locus_tag="ACHA1B_001645"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8433..8435),aa:Gly,seq:ccc)
     gene            8584..9336
                     /locus_tag="ACHA1B_001646"
     CDS             8584..9336
                     /locus_tag="ACHA1B_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFM8702412.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            9352..9831
                     /locus_tag="ACHA1B_001647"
     CDS             9352..9831
                     /locus_tag="ACHA1B_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HFM8702413.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(10082..11662)
                     /locus_tag="ACHA1B_001648"
     CDS             complement(10082..11662)
                     /locus_tag="ACHA1B_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HFM8702414.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCMASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(11655..12398)
                     /locus_tag="ACHA1B_001649"
     CDS             complement(11655..12398)
                     /locus_tag="ACHA1B_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702415.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(12574..13350)
                     /locus_tag="ACHA1B_001650"
     CDS             complement(12574..13350)
                     /locus_tag="ACHA1B_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFM8702416.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(13598..14434)
                     /locus_tag="ACHA1B_001651"
     CDS             complement(13598..14434)
                     /locus_tag="ACHA1B_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HFM8702417.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(14445..15374)
                     /locus_tag="ACHA1B_001652"
     CDS             complement(14445..15374)
                     /locus_tag="ACHA1B_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HFM8702418.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15566..15919
                     /locus_tag="ACHA1B_001653"
     CDS             15566..15919
                     /locus_tag="ACHA1B_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HFM8702419.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(15993..16649)
                     /locus_tag="ACHA1B_001654"
     CDS             complement(15993..16649)
                     /locus_tag="ACHA1B_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFM8702420.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            16875..18809
                     /locus_tag="ACHA1B_001655"
     CDS             16875..18809
                     /locus_tag="ACHA1B_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFM8702421.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(18895..20118)
                     /locus_tag="ACHA1B_001656"
     CDS             complement(18895..20118)
                     /locus_tag="ACHA1B_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFM8702422.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(20112..21983)
                     /locus_tag="ACHA1B_001657"
     CDS             complement(20112..21983)
                     /locus_tag="ACHA1B_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HFM8702423.1"
                     /translation="MKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQIDYIHQGVG
                     YGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYWGEIHERDQR
                     MVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQFFKIIVGTII
                     QKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYGLIYSVLEPE
                     KPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAMLWADLLPFKL
                     GEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLWLNKIFLLLA
                     LPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPNFHTLTNEKY
                     LKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKTYGQFIVRNN
                     VRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLYETGFAIECS
                     PEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLMTWENTFIPG
                     LEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKNNKKRLKLC"
     gene            complement(22004..23122)
                     /locus_tag="ACHA1B_001658"
     CDS             complement(22004..23122)
                     /locus_tag="ACHA1B_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFM8702424.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(23205..24038)
                     /locus_tag="ACHA1B_001659"
     CDS             complement(23205..24038)
                     /locus_tag="ACHA1B_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702425.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(24031..24948)
                     /locus_tag="ACHA1B_001660"
     CDS             complement(24031..24948)
                     /locus_tag="ACHA1B_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702426.1"
                     /translation="MIQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(25175..26299)
                     /locus_tag="ACHA1B_001661"
     CDS             complement(25175..26299)
                     /locus_tag="ACHA1B_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFM8702427.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            26482..27390
                     /locus_tag="ACHA1B_001662"
     CDS             26482..27390
                     /locus_tag="ACHA1B_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8702428.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            27531..29144
                     /locus_tag="ACHA1B_001663"
     CDS             27531..29144
                     /locus_tag="ACHA1B_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFM8702429.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         9388 a         5742 c         4765 g         9799 t
ORIGIN      
        1 cttacaggat tattattcga ttcagcatta tttttcattg cttcacgcat acgttcagaa
       61 ctagacataa tactatcggc attttcaacc ttagcaccat cttttctatc cgaaagacgt
      121 gttggcatgg aatcagcata ttttccagtt tcatcttctt tatttttagc taacataggt
      181 ttgctatttt tattaatagc ggacacagta ccatcatcta aaccttcttt aaacttactc
      241 ttggtatcat tagctatatc acgcatactc ttaaatggtt ttgttgctct ttcactagcc
      301 attgtagatc catctgaagc taaacctgat aatccacgtt catgagcata cccaagcgct
      361 ttccccgttt tattagcttt tttagaaagt gattgtccaa agttgcgttc aggttttcgt
      421 tcttcccctt cagcttgatc gtttccacca ttatttttcc cacctttaga ccggttcata
      481 ccacctgttc ctttacggaa tagcattgca cccattccaa aagcagaagc aagttgccca
      541 tagccttctt tgagtccaat atccacacca aagtatctca tgactgttcc actgcctttg
      601 attaaaacaa acacagcaca gatataagca attgttttta taaaaatatt tgctgagata
      661 ccttcgccag tatttaggta atttatgaac attgcaaaca tagataaacc gaacccttga
      721 aatccgactg tcaaatagca ctgtaaaata tctgacaaaa cttgttttga tcgttgtcct
      781 gtttctaagt cagtagcaaa tactaaaact ccgagtacac gtttaaatgc taactcgagt
      841 attgctgtaa ttataatgaa agcactaaaa acatacgcta ccgctaaagc aatcaatcca
      901 aaagaaattc cccacaggtt cgcttgatag cgataatatc ctgatttgat accatcaaca
      961 aaggttgata aaaaattatc tgaaaattta gtagcaacaa attcattatc agaattttca
     1021 actaattcat aacgcagatt atcagctgtt gggttctctt tttccatttt atcaattaca
     1081 ttatctgtca atacttgcgt aagatccgtt ttccagaaat tttcttttgt tagattattt
     1141 cggtcatttg ttttatcaat tgtcgaatat tgatctgtct tattaatata agctaaatct
     1201 gtcactccct gctcaatcaa tgaccatgct acaccgccat cttgattatt gatactagtt
     1261 gcgtcattat aaagagtctt tgcaaacatt attcctgaaa gtttttctgt tgatccaatc
     1321 aaagtcggca ttaaaagaat taatgctaca gacatcacta cgttcattcc aaccgatttt
     1381 aaatccactg ttccttttcc agtaatcatt ttgtaaccaa caaacatcag tgaaagtatc
     1441 attaaaccaa taacaactgt acttaagacc gattgataaa ctttattcat tcccgtactt
     1501 tcaataaagc taaacaaatc taacacttcg ggaatcatat tttgaatacc atctacaatt
     1561 gcaaacatcg attttataac agaccaccct atccacaatc caaactgact gtaaaaattt
     1621 ccgttatatt tttttaaata cgattgatag acaggattat tcaaaaattc agtttgactt
     1681 tccgtgtcat caaaccaatt gaaaatgctt gcttggacaa cattaccggt gaaaacaacg
     1741 ataaacatta aaacaagtat gctcaaagct aaccagtgta tttttctact ggcaatcttt
     1801 tctttaacta ttttcattat tacctccctc agcccatttt ctgagactct cagagagctt
     1861 ctgagctgtt tttctgtcaa ttatgatatg agttacacaa ttgtcatttt cagatcttaa
     1921 atcgagaact atagtgttga agcaaatagt ctcgattaat tcgagattat ctgtattttg
     1981 atctagacac caaacttgat ctattaaacg attttcaatc aaaataaccc ctcctatatt
     2041 caaagttctc aaatgaagcg gagatacccc tccacttcat ttgactcaat tctattctta
     2101 ttgcttatct attccttcac tgatttgcaa ttcaattagt tctaacgctt tattttttag
     2161 agaagcaaag atataatcgt ctttttgttt gatacggtga tctgtttttg ctcttcgtat
     2221 caagtcacgt aaagtcattg atagctgttc tctaacataa tctacaaaat acttgttatt
     2281 acagatttca tagataattt tcagttgaat tttttgttct ttttcagcag atttaatcgc
     2341 atatttgaat tttttatacc agtcataaaa ttgactgtaa tcgttattac ccactaattt
     2401 cagacagttt acaatattat ccccccatac ctgataaagc cattcttttt caattaatga
     2461 ttcaattaat atttcatcta attttttatt ttcaactgaa agtgaatcaa taaagtcagc
     2521 attttgagat tctttaaaat ctttaaaatc tttagaagaa tgattaagtt cttgtaaaaa
     2581 tttttcacct ggaagcggga atgacttatc accatcgaat gttgatttgt cggaaggtgt
     2641 atttttttca cttggactgt aatgttgatt tgtcggaagg tgtaaatttt cctcaatgca
     2701 cttttttttg tagaaatctc cttcgctgaa ttctggtttc aataaataat aaaaatttgg
     2761 attattcttc ccagtttttt tgttaaatcc atttttttta atcgtaatta atttatattc
     2821 ttctagctct ctcaaagcgc ttattaccgt tttctttgtt aaacaagatt tttcagctat
     2881 tttttctata gcaaaaatca aaaaaattct tcctttgctg tcaacttttg aattctctaa
     2941 agaatattca ttttgttttt tcaaatacat ataaactttt tttgtacttt gtttcatctt
     3001 cttatatttt ttatgtttat ctaaaaaaat cggatacttc aagtattttt cagcatatac
     3061 gtcatctttt gagtatgcat actgagcaat taatttatct atttcttcca tttattcctc
     3121 ttctttctaa taaatgttaa aatgtagtca aataaagttt tcttagaact ttattgtcga
     3181 gtgtttcctg tggtcgccaa actgtcggga acactccttt taattttttt caaagtattt
     3241 ttatattttc tatacttcat cattattcaa acaaacactt ccttttttct atcaaaagca
     3301 cgccacgcaa ctttttatac ttcatattct ttgataaacc ttgctaattc ttcttttcta
     3361 ataaattgac aatctccgat tatgcttact tttaaacctt tctctctgat aaattttttt
     3421 aatgtacttc tgctacagct taaatactta caagcttccc ccaatctaaa aacttctttg
     3481 cttagagatg tttcaattcg aacttgatct actgcttctt ttgcaactcg atagaaatat
     3541 cttcgcaatt cttgatctaa atccgatgga agaataactt gaatctcaga tttcattttc
     3601 tttgccccca ctaatttgac tacatgtatt caaattcaac ttttcgtcac ttttcattaa
     3661 aaaaaatttg atcaattgtg atattttcaa ttcctttttc tttcacaaga tacttcaaaa
     3721 taatcatttc ttctggagaa tagtttgttt taccgctttc tttgtttctt accgcttgta
     3781 ctgaaatgcc atatttttca gcaagttcag attgtgataa tccacaaaac tttctaaaat
     3841 ctttaggctt catgactcct cactcctcct tcttttcaac ttttcgtcac taaaagaata
     3901 acatatattt attcataccg caacgtaaaa ttcaactttt atctactttt tcatttcatt
     3961 atatgagaat gtagtgtaaa ctgtagaata gaatagatga aggtggtgaa accattttgt
     4021 ttgataaaaa cattaattct gaaattggaa aacgaataca agaaatacgt gtttctttag
     4081 ggtatactct tgaagaattt ggcgaaaatc tgacacctcc cgcaagcaaa agcaatgttt
     4141 ctagatggga aaaaggaaag aacataccca acaaagcgcg gctactaagt attgctaaac
     4201 ttggtggtgt ttctactgaa tatctactga caggtaattc tcaaaaaact aagaaatata
     4261 tcaagtattt attcaatgag attttttttg acaacggtac cttccataac aaattcaaag
     4321 atttcggtaa agacagagat aggcttggtc tatatgactt atttttagca gtatcgaaaa
     4381 catatagtct agataaatca ccttctttaa aagataactt tgtagaaatg attatagatg
     4441 atgtatataa aaaactcttg caaactgata aatcagatga ccaactcatc ctgggtttca
     4501 tatatatttg tcttgatgaa aaactttcaa acagacagaa aagtcttaaa agtatcaatt
     4561 atgaggtatt caattattta ggtgttgcat ttggtttaat tgatagcgaa atcaaatcta
     4621 caaacgcagg taacgatgaa gatttattaa attatttaaa agaattaaca tcttttattg
     4681 atgaaataaa aacaactaca ttcaacaaaa aaaaatattt tcaaaatcaa tatgatatag
     4741 aagaataaag attacatttt cctatcaaaa gcacgccacg caactgatag gaggaaaaac
     4801 aatggcaaca attaaacaat atgaaaagaa agacggaacc aaagcttgga tgtttcaaac
     4861 ataccttgga atcagcccgc taactggtaa agaagtccgt actacacgta gaaattttaa
     4921 aacaaaaaaa gaagctcaaa tagagcttaa tagactactt gtagactttg aagagaatgg
     4981 acttaaaagg gaaacgaacg aaactttcca agaagtgtat gatctctggt atgaaagcta
     5041 taaaactact gtaaaagaag tcactcaatt aaaaattgag atcaagttta ataaatggat
     5101 tcttccaaaa tatgggcagt ttagaattaa agaaattact acaaaacatg ttcagaagat
     5161 attgaatcag tgggctaaaa caacagatca atataaagtc ctacattcta ccgtaagccg
     5221 tattttcaaa tacgcaatga ctctagggct gatcactaaa aatccctgtg agctcgtaat
     5281 catgcccaac agaaatgttg aaaaaaagaa ggatactgtc aaaatttatt cacgagatca
     5341 attagaaacc ttatttcaat atttggaatc caaaagaagt acgtataggg cagagtacga
     5401 taaaacttta ctgcgctttc tattttttag tggctgtcga atcagtgagg ctttagcctt
     5461 agactggtca gatattgact ttgattcaaa caccgtcact ataaacaaaa ccttaagcca
     5521 aacaaaatat gggtacaaaa tttcaagtcc aaaaacgaga aatagctatg gttccctatc
     5581 tttagacaat aaaaccatta attggctaaa gaaatggcaa atcaatcaaa aaagatatat
     5641 gttaaccctc gggattactg atccaacaat gattttttgt ggaatctaca aagaaatcat
     5701 tactaaacac gctatctatt ctcgtatgat cacaatctgc aagaattctg gtattccatt
     5761 tctaggtaac catgtaacca gacacactca tgctagtatg ctgttagagt cgggagtctc
     5821 catgaaggaa gttcaagaac gccttagaca ctcatcaatc aaattaacaa tggataccta
     5881 tgctcatcta actaaagaaa ccaaagaaaa aaccgttgaa aagcttgcag agcacctaaa
     5941 tttctagcgg aacgtattca atcccgtatt caattcaaaa caaaaaaaag ctgaaccctt
     6001 atctaccaag ggttcagcta tcatttacag cttattcttc ttcttccgcc atgaatgtat
     6061 tgaatacttc ttcaatcatg tcccattctg cgtctgtttc gatttgttct aactcgcctt
     6121 ctgttccatc ttcgttttcg atgtatgcat aagcttgtaa ttctacatct tcatcttctg
     6181 aaacaccagc aggatataaa agaacatagt tacgtccaaa ttcttcttgt ccgtcaactg
     6241 ttagtaggat ttcatataat gtttcatttc cttggtcatc caccaatgtg atgtgttcgt
     6301 gtccttcatg gtcgtgggaa tggttatgtt ctgtcataag attacctctt ttcttttatt
     6361 attaaaataa ttgcttacct gagccgtcta aataattttg taagatcatc acagctgcta
     6421 atttatcgat gacttttttt cgtttggctc ttgaagtatt tgcctgctct actagcatac
     6481 gttctgcctg aacagtggtt aatcgttcat cttgataatc aactggcaag gagaatagtt
     6541 ctttgatctt ttctccgtat gacatggaag cttctgccct tggtccgatg gaattgttca
     6601 tatttttagg taatccaact acaaaccggt ctacttcata ttgtgctact aattccttca
     6661 accgatcaaa gccaaactct tcttctgctt cattgatccg aatgatctct actccttgag
     6721 ctgtccagcc aaaggggtca ctgatagcaa cacctactgt cttagaaccg acatccaagc
     6781 ccattactct cataaattca ctccatgatt tgagaggtag tccttgacaa ttacttccat
     6841 gatctcatcg cgttcgtgac ggcgaatcaa atttcgagca tcacgataac gaggaatgta
     6901 ggccgggtct ccagaaagca agtagccgac aatctgattg attggattgt agcctttttc
     6961 ttccaaagcc cgataaacaa tcgctaatgt ttcgctcact tcttttttgc gactatcgtc
     7021 aaaaccaaaa cgtacggttt catctgtaaa acccatgatt ctacacctct ttcccgcaag
     7081 gtaattccag cttaccttct acaaccttat tttactcgaa gaaagggaaa actacaaaca
     7141 aatattccaa acttccgaat aaattaagaa acactatttg tatgtttttt tccttttttc
     7201 tgtagcttta tcaaaagtac tcttttcata aagtatacgc tatatttctt tgaatgtatg
     7261 tttttacaca attttttcat aatattcata aaaaattcga atagctgcta ctaatttttt
     7321 gtttttgttg cttgtcctgt ctcataattg atcgtgtagc catcttgaac attgtagata
     7381 aagacattga attcaatttt tttgtcttca atgctttctg cttccaattg cactcccctg
     7441 gctaccagtt cattcccctc aaaatgagga gtgacacggt agcgtacatg atgatttgtt
     7501 tctttgatat atgccgcaat atcattttcg tgagcaagca tgtatggagc attcaacgaa
     7561 cgtgtccctg tcatcaagtt tttaatgttg ttattttgac cagtcagctg gaaaccaatt
     7621 aaatggctgc gattatataa ccattgcccg tcacttaatt tcttttgttt ccaacctgtc
     7681 gggtcaatat acaaaggctc tctcttttca gtagggaaca aatcttttcc aagcatagca
     7741 ttggcttgtc ctactctgtt caatttatca atatttgaat agctttccca tgttcctttg
     7801 gaaaggctaa gatcctcttt tgtaaattcc ggctgattcc cattgatttc tatttcttga
     7861 tgttttccat catattctgg cacatccgct acttgagaag cttgtggtgt ggaatcaaaa
     7921 atagttgtaa tctgctgaaa gatatctgaa tctttttgtg tggtggaaac accgaatgcc
     7981 cctgcaatca cagcagcgac gatccccacg atcgccttgg ttgttttttt gctcatttct
     8041 ttactccttt actaacagct ccctaaatct taacatatgt tcccctataa ataaatacta
     8101 gaaagaaata gaaacagcaa aaaataaaac ctgttttaag atggcttaaa aatacaaaaa
     8161 agagacggat tcctcgtctc taatcagtca ccactctatc tgtaaggtat ttattattat
     8221 tcaaaaattt tcttcatact caagacaata cactgatttc acaaccgctt ggtaaacggt
     8281 gcgcaaaagc ttgcatctgc ggtaataagt ccatccaagt taaaaacata agaagttgtt
     8341 tttgcttggc tgttcttatt acttgttgca gagcagcttt ttcacaacct attttaagcg
     8401 ggtgacggga atcgaacccg cgacatcagc ttgggaagct gggattttac cactaaacta
     8461 cacccgcaat acaaaaacag tatacgcctc ttttattcct tcctcaagtt tttttattct
     8521 ttacgcttct ggtatgtttt gtagtaaaat aaaactaatc aatcaattat tggagaagat
     8581 gctatgacgg gaaaagaatt agatctgttg ctggacactt gtttactcgc tgggaaaatc
     8641 atgatggaaa gcaatgcgga gatgtatcgg gtagaagata cgatgagtcg aattgcttta
     8701 gcttctggaa atttccgttt ggtcagctat gtcactcaaa ccggtctctt tattggtctt
     8761 gatcgtacct cgaccatccg aatggaacaa attaccaacc gttcgattaa tttagaaaaa
     8821 gtagtaaaag taaatgatct ttcacgtaaa tatgttgctt cagagctaac attagaagaa
     8881 ctttactgcg aactgcaagc aatcgaccga gaccgttctt tctttcctgt ctggttgcaa
     8941 atcgttagcg cggcagtgat cagtggaaca attatggtgt tatttggcgg aaagatgacc
     9001 gatttacctg tgactttagt cattggagga ttgggatacg cagcttatct atatagtttg
     9061 aaatttttta gaatcaaatt tttatcggaa tttttatctt ctttattgat tggcatagcc
     9121 gctatctaca gcgtacgttt tggcttagga agcaatcagg atctaatcat tatcggatgt
     9181 gtgatgcctt tagttcctgg agttcaaatt acgaacgcta tccgtgattt gctagctgga
     9241 cattatgtct caggagtttc tcgcggaaca gaagcgatga tgactgctac gatgatcggt
     9301 tttgcgattg cttttatttt ccagcttttt tattaggaaa ggaacacaag tatggggacg
     9361 atatttattc agttttcttt tagtttttta gcgactgcgg catttgccgt tattacaaat
     9421 gtacctaggc gttcattgat ttgttgtggt ctttctggtg cttttggctg gatgatctac
     9481 tggatctgtg ttcaaatagg cggatctgct gcttttggtt cattgcttgg ttctttagga
     9541 gtagcattca tcagcgatct tttctctaaa cgtttgaaaa tgcccgtaac gattttcaat
     9601 attcccggga tggttcctct agtccctggt ggtttagctt atcaagcggt tcgaaatctc
     9661 gttactgaat cctatcgaga agcggctcat tatgcggtcc aagcaattat gattgctgga
     9721 gcaatcgctt taggtcttgt attatcagaa gtctttaacc ataacatccg taatttcaaa
     9781 gtaaagcgtg acgcaatcat gatgaaacga aaaaaacggc tttttaaata aacgaagtgt
     9841 aacaaagaaa aggttgtgaa agagacgttc agccttgagc gatgacaaaa tatctcacaa
     9901 acattgcgac aagtaaccgc aggagcaata agaagtaatt atgagtatta aaaaaagttt
     9961 tgtaaaaata gcttctcaca tttttacata aaattgactt aatactgaga aactgacttt
    10021 tgaacaccct ctatctgtaa aaaaggggct gcgacatgat ttttgtcacg gcccctcttc
    10081 tttattcaaa ttttttccaa aacgttcgtt gataataaac gatccataga gcggaaagta
    10141 ttagaactaa accgatcaca ggaatattca ctaaccaaaa tggataaaac aaagccaaca
    10201 ttccgtataa gacgataaga ataatactga tgatcaatga acccatcata gttgcgacta
    10261 aacccaaact tcctgaacct ctgttaaata attggttaat attggtccag ttcagcagca
    10321 gcaaccgata atctctagcg aaataacgta gtgacaataa gtagcagccg aataaagaac
    10381 caaatagcaa gctagggata aaaaacaaag gcagctgaaa agacagtccg cttaataatg
    10441 cgatcccacc agttaaaaaa ctctgcaata tccatccgaa tctgaacttt tcttttaaat
    10501 attggttcat agagattggc aaagaacgga taaacagaaa attttcttga tccaaagaaa
    10561 taagattgct gataaaagaa gtctgattaa ctgttaagaa agccaatgcg atccctacca
    10621 ggaaaacaac accgattaac ttattatcta aatcagttaa ttttatttcg cctcctaggg
    10681 caaaagcaag aataaaaatg attggagtta acaaggaaga agaaagaact tgcataatca
    10741 aattaggttc ttttactaat tgagcattgt aactaaataa aagctgatgc acattttggt
    10801 tctttttatg ggttcttttt attttgaact cactgtttga atcagtcagt tgctctgtaa
    10861 gctttggtac tatcagctgt tttacagcaa ggaaaaatcc cagagccgtg atagctagta
    10921 ttccccaacc caataaacct tgttgagaaa gtggctgact ggcagcatca tagaatggca
    10981 ataatatcga aatcggatgc cgatctgtta actcattttc aatagtcccc gtttgatgat
    11041 tcatccacat gattccagca aatgcgatca gcatcgagct gccaagcaag atactagaaa
    11101 ctgtttttct atgtttttta aacactgctg ttcgagccaa accaaaaaca atcaaactag
    11161 ccatacaaaa aagaataatc aaaaatagag aaaacaaaag gattgagata atgatagtaa
    11221 gcaaaatccc tagatcagct cgccatccgg ttaaaataaa catgactaga agcggaaaaa
    11281 caaaaggaat gatggtcaaa gcaactacca aaatctttgc tgaaaaaacc tgttcttgtc
    11341 caaaaggcag aggcaaaaat acttgcaggt catttccttc aaaaaagata ttataaatga
    11401 ctgatatact ttgagttaaa cctaacatac caaaaagtgc cacgtaataa gtaaagaaac
    11461 ctggcaattt aacaaagttc atagcaaaca tagcaaatcc gtaaatcagt aaaaaaatca
    11521 gccctgaaaa aagattttga gacaaaagat agatagttaa tcgctttccc ttttttcctt
    11581 tctctcttgc tttattcgtg agctgtggat taacatataa aagattaact cgaattaatt
    11641 ctaataattg tcgcttatac atacggtcca tctcctgtcg cttgccttcc agccattttc
    11701 aaataaatct tttctagcgt ttcatcaggt gagccattca ataattcact aactgccccc
    11761 tgataaatca attcaccttt cttcaaaata gccagtttat cgcataactg ttgtgcggta
    11821 tccaatacat gtgtagaaaa aatgactgtt tttccttttg cggcatgagc cttcatcatt
    11881 tctttcaaat caaatgctgc ttgaggatca agtccttgca aaggttcatc caatacccaa
    11941 atatctggat ctggcagcaa cgtgccgatc aaaatcgttt tttgacgcat tccatgtgaa
    12001 aaacttgcga ttgtttcatt ttgatgacta tacatatcaa aaagcgctgt caattctgct
    12061 aaacgctttt cttttttttg tgtgtctaat tcataggcag ctgaaatcaa gtcccaatat
    12121 tctccagccg tcaattgtaa aaaaatatct ggggaatcag gcacataacc gattttttgt
    12181 ttgatactca atcgattttc cgtcaatttc attccatcta ctaaaatcgt tcccgatgat
    12241 ggttcaataa tactaactaa acttttaatc gtagttgatt ttccggcacc attatgtcct
    12301 aaaaatccaa aaatttcccc ttgtcttatc gagagagaca agtcttttaa tgcttgtttt
    12361 ttcccgtaac ttttacttac attgatgaat tcaatcattt ctgtactcct tttgtttgtt
    12421 attacttttt attgtaccct tcgttattgg tggagtaaat gtcaaaaaga gtgcataaca
    12481 aaaaaggata gaaacgacta ggctgctact tgggttgttc tcttctacag gaaaacactc
    12541 ttctaacagg taagatatga gtctttgttt tctttaaaat gattcatttt ctatcttttc
    12601 ttgcataaaa ttctttagtt tatcaatact tctctttccc atctctagtt gttctccatt
    12661 tgcaaatgtt actatttcgt ttactctgct aatagatgta atgttttcag tattaatgat
    12721 ataagctttt aaatctttac ataaatactc atattcgagt gattttttat attttttaat
    12781 tgtgccgttt acgagaatct cttcatcttt caatactagg cctattttat ttttataacc
    12841 tggcatgctc attagataaa ggatttcatc gtaatggata tagtgatcgc tattaccata
    12901 acggacagtt gtccaccttt ttttcgtagc atgttgaaca ggatagtttt ctttttcttt
    12961 caataagtaa ctttggatgc tttttttatt tttttcataa gtgaattctt ttatcaaata
    13021 accactaggc gtaatctttc gattaataac agttattgct ttattcggat gagacgttag
    13081 ataaacaatt ttacactttt cattcttttc tctaagcatt tcgcctagtt cgataccgct
    13141 ataataggcg ttcaaatcga tgtctaggaa aaaaatatct gaggaataga tttcattatt
    13201 tttaatgaat tcaacaaatt gtataacgtt caatccctga acgatctcaa atttccaagg
    13261 acttaataaa attctggatt cttccaaaat ttctactagc attttttcaa aaaccaaact
    13321 atcatccaaa ataaatatac gcgttaccat aaaaagtacc tccactcgat attttactat
    13381 caaaatcatt tcatacaact tttcaacata catgttagga ataaattgta attctcttca
    13441 caatcttttc caacaccttt gaaaccgata tcaaatactt tcaggatgct gcttctaaaa
    13501 taaatatcaa acaaatgaat acatcatgca aaaaaagcca gacaaccgac gtccttgcgt
    13561 gtcagctgtc tgagctatgt ttatttattt tgttctttta aaaagaacga tacacatact
    13621 gatttttcgg agcagagact ttctcagcgt ttgtaacaac tacagatggg atttcacgct
    13681 tgaatggttg ataatagtct gattggatgg ttccttctat tttataccat tcatcatttt
    13741 taaccgttac tccttccggc atatgcgtca acaaaccaaa gactcctgaa tctgccacac
    13801 aatggataat gccgaatcgg aacaagaaga tatctgtatt gctatcgttc ggtgtttggt
    13861 aaacaaatcc ttcatagctg atttttttgc caatgaattc gctagggtaa ttataaatta
    13921 gctccataac ttctaaatag ttttcatctg tgatcttgat agtttgctta tccccatact
    13981 tttctttcaa ctcattcatt tggtctaagt agtctgattt gttgaaataa atactggtat
    14041 ccggctttaa gtattgtgtc tgcatctccg gatcccctac tgattcttta cttactggga
    14101 aattaaatcc tttggcttct acgatcgtag tgtcgagact aactgttgga aacaacgtcc
    14161 ccacgattac tggcaaagct agcagtacat aagcgattcc acgttgataa ggttttgaca
    14221 acccatggtc atgatcgtgc tcgtgtgcct tttcttctgc ttttccgttt ttgacccaca
    14281 aatacagctg aactaaagcc aaaagagcag ataaaatcat tgaaagaata gctaagtagc
    14341 gataatggac attgatatat tgatcgagtt tgccagaaac ttgcaagtac atcatcaatt
    14401 cgaaataccc agataaaatc aaaaaccgca gcatattttc cctcctaaat aaataatgtg
    14461 aatccaataa cgctaagggc aatcagtccg atcagcgata aaataaagcg tcctgtaaaa
    14521 tatcgtttca tcatcagtag atttttgata tcgaccattg ggccaaagac caaaaaggca
    14581 gctacaggtg ctgtgccgaa cagacttaac aaagaagatc ctataaacgc atctgcttct
    14641 gagcaaagag acatcgtaaa ggccaataac agcatgatga taatggctaa aatctttgtt
    14701 gagccgagcg ttagcataat tctagttggt aaataagtct gcatcgcagc tgcgattaat
    14761 ccgccaatga tcaaataacg acctgtatca aaaaattcgt cgattgaatg tgtcaacaca
    14821 tgcccagttt gatggatcag ctgatttttt ggttcattct tctcactttg ttcttcttca
    14881 tggacatgat gatggtgatt ttctgctact ttagacgtga ttttttcttt caatacagcg
    14941 tctttttgaa aataggcaag ccagacacca atcacaaggg caacaaaaaa gctgcctatc
    15001 acccgccagc ttgccatctg ccaagaattg ccaaatgcga taaaagtgga aaaaatcacg
    15061 attggattga tgatcggagc agtcagcata aaagcaaacg ctgtgtgaac tggtacgcct
    15121 tttttaacaa attgatgaac gatcggtacg atgccgcatt cacatgaagg aaagaaaaat
    15181 cctaagatcg aaccagtaaa aatagagaag atacgatttt caggaagcca tctcttcaca
    15241 cgttctgggg tcaaaaatac ttgtaaggcg cctgagataa gacagcctaa taatacgaaa
    15301 ggtaatgctt caataacgat cgataagaaa atcgtactca tctgcaaaac cgaatttgga
    15361 ataaaagaaa acatgagttt cctccttttt atttctagtt cattcgcttt gcaaatatac
    15421 gcttttattc aaaaaaaaca agttgctctg taaattttta cacaactctt attttttacc
    15481 aaagcacttc aattgacttt ttctgttatt cccattaaat taaggtctca tacatatcac
    15541 ttctatcata aaagggagaa taaaaatgaa acaaaccact aacttgactg aagttcaaga
    15601 catactgcaa cagtcatccg ttgccgtcat ttatctttcg atgcctaatt gcagtgtttg
    15661 tcacgctgtt cgtccacgac tagaggaact tctcacacat tatgatattc cggcacttca
    15721 tttggatgca tttgaaacac cagaagtagc tagtaaattt gaagtgctga ctgcgccagt
    15781 tgtcctgatt tttcatcaag gaaaagaagt ctttcggcaa gcacggttca tcgactttaa
    15841 aaaaatccgt tatctactag atgaactgac agcagaagat gattcccttt cttatgaaga
    15901 aatcttccga acaaaataat cgttgtccaa acagaaaaaa gcgattgaac aagtgaaagt
    15961 tttgccttca tttgttcaat cgctttttat ttttattctg ctgtattttc ggaatgcgca
    16021 tttgcgtcag aatgcaagaa atagatcaag gtttgcaatt cattcgtcaa atcaacattt
    16081 tggatcaata catctgacgg agcattcaat cgagcagcgg taaagttcaa gattcctttg
    16141 attcctgctt ccgttaactg attgactact tcttgtgctc tttcagcggg tatcgttaaa
    16201 attgctactt cgatttgttg gatcttgatt tgttctgaca tatcttccat tggataaacg
    16261 gggataccgt ctacgatgcg cccaacgatt tcctcattca catcaaaagc acaactgata
    16321 cgtatgctat tactttgatg gaatttgtat tttagtaaag cacttcccaa gttccctaca
    16381 ccgatcagcg caacatttgt caattgatcg tcgtttaatg tctttgcaaa aaagtgcata
    16441 agatcttcta catcataacc atacccacgt tttcctaatt cgccaaaata agaaaaatct
    16501 cgacggatcg ttgcactatc tacttgaacg gcttcactta attcagttga agacactttt
    16561 ttctttccag cattatttaa aatccttaaa tagcgataat acaaaggcag tcttttagct
    16621 gtcgcctttg gaataatatg atctttcacg aaatgacctc cacgtattgt ctaattacat
    16681 ctttgatttc tccatcatag cagtatttat aggaaaaaat caattccatt gctcagatat
    16741 tgtgaaattt tattctttat tcatttattt atcatttctg caaatctcgc agtataatgg
    16801 aatttatggt agactactaa ttgaaaaata gttttttatt tgaggagaat tcacaaagta
    16861 gaaaagagga ttccatgata ttattacaag ccaatcagat tgctcgccat tttggtgcag
    16921 aagtcttatt tgaaaacata catttagaaa tcagtacagg cgctcgtgtc gctttagttg
    16981 gcagaaatgg cgctggaaaa tcgactttat taaagatcat tgctggaatt gaagcacctg
    17041 atgaaggaaa gatcgctaaa aataaaacag cgactctcgg atacctcgct caggacacag
    17101 gacttgattc caatgaaaca gtttggaacg agatgctgaa agcttttgaa caagttagac
    17161 aaatggaaga gcggatgcgc gagctagaga ttttcattag cgaaggtacg ccagacacac
    17221 ctgcttatag ttcttattta aaagaatacg accggctgca acacgatttt tcagatcgaa
    17281 acggctatgg ttatgaaaat gaaattcgtt ccgtattgca tgggtttaaa ttcgattctt
    17341 cattttatga tcagaaaatc gatactttat caggcggaca gcgcacacgt ttagctttag
    17401 ctcgcatgct tttgcaacac cctgacattt tgattctaga tgaaccaacg aaccatttag
    17461 atatcgagac actttcctgg cttgagaatt atctgcaaag ctatactggt gcattattga
    17521 ttgtttccca tgaccgttat tttttagata aagtagtcaa tgaagtctat gaattaagca
    17581 gaagaaaaat gcgccattac aaaggtaact attcgaaata tctagatttg aaagcagaac
    17641 agttagcaag tgaatggaag gcttatgaaa agcagcaaac agaaatccat aaattagaag
    17701 acttcgttgc tcggaacctt gttcgcgcct ctaccacaaa acgagcgcaa agccgcagaa
    17761 agacattaga aaaaatggac cggctggatc gtcctcaagg ggatgaaaaa caagcaaact
    17821 ttctattcag tatagaaaag ccttctggaa atgtagtctt gcaaatcgaa gatgccgcta
    17881 tcggatatga taatgtcacc ttatctgaac caatcaatct agatatccgt cgtcaagaag
    17941 cgattgctct agtaggtccg aatggtatcg ggaaatcgac gttgctgaaa tcaatcattc
    18001 accagatccc ttttatccgt ggaaaagaaa cgctagggac aaatgtcacc atcggctatt
    18061 acgatcaagg tcaagctgat ctgcatacaa acaagacgat cctagcagaa ttgtgggatg
    18121 agcatcctac cactccagaa aaagagatcc gaagtgcttt aggtgctttc ttattttctg
    18181 gcgaagatgt agaaaaacca atccctctgc taagtggcgg tgaaaaagca cgggttgctt
    18241 tagccaagtt agcgatgaac aaagaaaatt ttttgatttt ggatgaacca acaaaccatt
    18301 tagatattga caacaaagaa gtattagaaa atgcattgat cgattatgac ggcacactgc
    18361 tttttgtttc ccatgaccga tatttcatca atcggatcgc gacaaaagtc gtcgaactct
    18421 ctgaaaatgg cagcaaagtc tatctaggag actatgatta ttatttagag aaaaagcagg
    18481 aagaagaaga aatcgccgaa ttgttggcac aagatgagcc agaatctgct cctgctccca
    18541 cgaacaaatc tgattattac caaagcaaag aacagcaaaa gcttatccgt agccttcaac
    18601 gaaaaattac tcaggttgaa gaagaaatgg cgcggatcga tgaatggatc gatcagttgg
    18661 aacaagaaat ggtcgcgcca gaaaacctgg aagatcacgt aaaactcaat gagctgaacc
    18721 aagatttaga agctgctaga caagatcaag aaacaaaatt gacggaatgg gaagaactaa
    18781 gcttggaatt agaagaatat gaaaattaac gaaaaaacca aaacagaaac cattcatgct
    18841 gttttggttt ttcttttttt attttatcaa acaaaaattc catatttacc tttttcacca
    18901 ataagaagac caattactag tcattctcac taaagcttct aaataatagt aatcacccca
    18961 aatacaaggt gtatttaccc cattattttt gggcttatta taaacagact gtgttaaaaa
    19021 gccatcttct tcttccgttg tagcatatct ttctttcaat tgtcgcataa ttttccaaac
    19081 agcagactgg tataagttct tttctgtttt gtctaataga cctgattcta ttaattctaa
    19141 taatccacaa accatgatca ccatactaga tgtatctttt tcttctctgc tagaatcatc
    19201 aaagatcaaa tcccaataac aaatggtatc ttctggcaac cgattcataa aataattggc
    19261 taatattttg cttaaatcaa aatatttttg ttctttcaaa taacgataac ttaatgcaaa
    19321 accgtaaatc ccccatgctt ggcctctagc ccaacaggaa ttatcactat aaccttgatg
    19381 cgtacttcca tatcttggtt ttccatcttt gacatccata taaaatgtat gataagttga
    19441 accatcttct cttactaaat aatctgctgc attttgaata tgagcctgag cagctttttt
    19501 atatttttga tttccagttt cttcactcgc ccaatacaat aatggaagat tcatgcaaca
    19561 atccatgatc attctacctt gttgtgaagg atcactagga tctccccaag cttgtataac
    19621 tcctgccttc tcccaaaaac gctgaagtaa tgtttctgca gcatcaattg aagcttcctt
    19681 catttttcga tttcccgtta ttttataatc tgctacggtt gataaagaat acaaaaaacc
    19741 aagatcgtga tgattagtga taatttgaca gtcaatcctg tggataaaat ctatatctgc
    19801 tttttcagct gtttgttgaa ataaaggatc acccgtcttc tcaaataaca accaattaat
    19861 tcctgtccaa aatccttctg tccaaccaat attgtctctt aatggataac gtccttttat
    19921 aggacactcg cttgggaatt gatactgact gttactgata cgtttgatta acctctccgt
    19981 gtgtctgcga caacgctcga tctcattatt ccattctttt tccattaatt ctttataaca
    20041 ttcatttatc catttttctg gatgtattat ctcttcaaac atcactttat caagcatttc
    20101 cccaccagcc tttagcataa ttttagtctt tttttattgt ttttattttg gatagttagc
    20161 ccggttgtcc catcaaaatc aattttggga cgattgttcc atacttctaa actataatcc
    20221 cgatcttgat gagcaaccac tcctgttccg agccaatggg ttccttttcc aaatgtaccc
    20281 tctaatccag gaataaaagt gttttcccat gtcatcaagt ttgtattggg caaacccata
    20341 atagctgtgg attttcgttt aatagtatcg tcacttaaac agataatacc tgaaaagcca
    20401 gcttcactca ccctatagtt ttccttgtct tcttctatga ttattccttc tttctcagga
    20461 gaacattcaa tagcaaaccc tgtctcatat agaacatatt ctgtatctaa ttctactttg
    20521 tgtacgcgaa tctgccagcc ttcaaaagga ataagccaag ttctgatttt tgcctgtaaa
    20581 gtaggttccc atgtagaggc aagtacctct ttcttacata caatgtctcg tacattattt
    20641 cgaacgatga actgtccata ggttttgatg ctctcattct taaaactggt cgtgatatat
    20701 gtgtccgctc gctgaatccc tagcattgaa tccattgcca tttctgcttt caattgattc
    20761 gctcgcggta tcgaaaaacc aaattgacta gaataagcaa attttaaata tttttcattg
    20821 gtcaatgtat ggaaatttgg ccctaattgt cccgcattca aaaaaaatgt atgtccatta
    20881 tcatgttgta tgagcaaatt ggcttctgaa agaagtttag ttccttcacg aataggcata
    20941 ggcatttctt tagccgtcca atactcatgg tcttcaggta gcgccaacaa taaaaaaatc
    21001 ttattcagcc ataatggaga taacgtacta ttatagggtt cagtcaatgt caattgaggg
    21061 taggtataac caatattcag gatacctttt tcatcaaata tttctttttg catccaccat
    21121 cttatattcc gattgactaa ccccttgatt tcacctaatt taaaaggcaa aagatcggcc
    21181 cacaacatag ctgaccaaaa gcttgaaact gcaaaacgat aaatcatgct tcgaccaaaa
    21241 ggcacatttg caccatcttc cgcaaaaaaa tgaatatagt ctctagaaaa atcaatagct
    21301 cggttcttat atatctggct aatgggcttt tctggttcta gtacgctata aatcaaacca
    21361 taataatgaa atgcaaaagg attataataa tcttggcgac ctcttgaact gtctcgatac
    21421 cagccatttt gaagataaca attttctata ttatcaaatg cttctttcag tgctgattct
    21481 ttaactggat aaccaaattt ttggataatt gttccgacaa ttatcttaaa aaattgccaa
    21541 ttaccatctg cacattcata ttcaaaaatt tgcgagaacc aatgaataat ctggcttttt
    21601 tctcctgtat ctaatttttt ccataataat tgttcatgat gatataacgc taataacatt
    21661 gcgggcattt ctaccatacg ctggtctctt tcatgtattt ctccccaata atcgggatgg
    21721 gaaggatctg ttccagcttt tattcctgat agaattaatt tcaaccatcg ttcatctaat
    21781 tggtcaattg cgggccccgc tccccataaa acccgagaga atccttccat tcctgcaatt
    21841 ttatttccat atcctacccc ttgatgtata taatcaattt gtgcgccact tgctcgataa
    21901 aacggctgga gtggttgatt tatcttttta aataagtcaa agtaatcctg tctggtcctt
    21961 aatagtggta ctggatgttt cattgtattt tctcctcttt ttactaccaa atagctaatt
    22021 ccgactgttc taatcgaagt aagccttcaa taaaaaaata atcagaatag atcagtggca
    22081 cattataagt cagttctcta tggtatgctt ctgctccgcc tccaatgatc ccatcttcat
    22141 ccatattcca atttgcatag tgcttttctg tcttttggag tatattgata gcagcttcat
    22201 gatacatttt tgatcgtaca gaggaaacat atcctgctaa ttccagaaga ccgcatgcag
    22261 cgcatactcc agcactggta tcaatattcg aatcttttac agcaaaatca atgagaggaa
    22321 tataaccagt tttttcgatt ttctgaataa aatttactgc tatcttttct gctatagcta
    22381 gatagtacgg attttttgtg taacgataac ttaacgcgaa tccatataaa gcccatgcat
    22441 ttcctctgct ccaacaagaa ttctcattgt atccttgccc gccaagtaac cgaatatatt
    22501 tccctgattc tgcatcaaat tctgcgatat gcccggttga tccatctttc ctcactagat
    22561 acttagctgt tgtatctgca tgctgccgag caattttaga gaacctcgga tcaccagttt
    22621 ccctcgaagc ccaatacagt aatggtaaat tcatcatact atcaataatc atccaaccag
    22681 gtttatggtc attccatgct actaaatagt tccctgaaat attatagcgt ccagcaagta
    22741 ccgtagctgc atgtaaccct agttgtcgac tatgtttgtt ttgagactgt tgataatgtg
    22801 caatagccga tggtaagaat aaaaaaccta catcatgatg aacgtctgaa aaatggtaca
    22861 gggcagattc taataattgt tcttgttgta ttgctgcctc tttgaacttt tctcgttttg
    22921 tcttgtgaaa gagctgccat aaaataccac tccaaaaacc attggtccac cagtcgattc
    22981 ctctgtcctt tattacgtct gtatattttc cgttgtaaga aatatatgga attttattcc
    23041 ccattctgtc taattccgca tctatctttt cagaagctac attcaaaatt tttcttgacc
    23101 attccttcgt ctgttcattc atggatatcc cgccattctt ttaattttta tgaatgtgga
    23161 gttgctccta gaacgaacta gatggttaac attcgttatt ttttttactt atttgcagct
    23221 ccaatgtcat tctccttaaa tttagactgc gcccacacat aaatcaagac cattgggatc
    23281 actgaagttg ctaaaattag cataattgcg ccataattaa ttggctcacc tgtactagaa
    23341 accgtcatat ttttgataat taagggaacc gtatatttat ctttatctga aagcatgact
    23401 aatggaaata gatattgatt ccaacttccc ataaagataa gtaaaccact agtaataatc
    23461 gtaggtgata aaatcggtac agcgattttc gtaaaaatca cccactcatt ggcaccatcg
    23521 attctggcag cctccatcag tgctgtagga aattgactgc tatattgtcg catcataaac
    23581 actgaagttg tactggcaat cgaagggatg atcacacctg cataagtatt cgataatcct
    23641 aaacgactca taatgtaaaa taaaggaatc aatgtggtaa aaaaaggcac catcctagat
    23701 agcataactg tattgaacaa cagtttattc cccataaaac gatactttgc taatgcataa
    23761 cccgccattg tagaactggc tgtagctaaa actgtactga ttacagcaat aacaatcgaa
    23821 ttccaaataa tcaagggata attatatctc gccatgatgg cttgccagtt ttttaatagc
    23881 atatccccaa acttgaaatt gattccgcca cttaaaattt cttgattact ttgcgttgaa
    23941 gctacaatca tatataaata tggcatcaaa aatattaagg caccaaacac aataatgacg
    24001 tacgtaaaaa ttctgctttg tatcttttgt ttagtcattt ttatcacctc cgaatttaaa
    24061 ttgaatagcc gataatataa cagatacaaa caccatcgtc caggcaatag cagaggcttt
    24121 tccaaaatca accatttcaa aacttgtttt atataaattg actcctacga ccaaagctga
    24181 attttctggt ccattggaag tcccaaagaa tatatttggg atattgaaat tacccaagcc
    24241 attgatagtg gctaaaactg tggccattaa aatgattggc tttagcatgg ggatcgttaa
    24301 taaaaagaat tgccgaaatt tcgatgctcc atctatttca gcactttcgt atatctcttt
    24361 agaaatccct tgaagaccag ctaaaaataa aatagtgtta tatcctacac taagccaaat
    24421 catcgtgatg atcattgata ttcgtatcca aaaaggattt gttaaccact gtacaccgtt
    24481 aattcctagc gcattcaaaa atccattgaa taacccagtc ggattgaaaa aagtcatgaa
    24541 tacggaagct acagccaccg ttgatgtaat ggttggaata taatagacag ttctaaaaaa
    24601 tccttttcct tttaactgtg ctgaattcaa taaaacagca aagtaaatag ctaatagcat
    24661 cgttattgga attgatcctg ccatgataat caaaacattc gtgtaagatt taataaacaa
    24721 tggatctcgg aagatagcta gataattgtc aaatccaaca aattcaaatg agtagccaat
    24781 tttcataaaa ctaaaagcaa acgagataat gatgggaatc aaaatcgtca caataaagaa
    24841 aataacaaaa ggtgtgacca atccataagc acttttttta tgagacgtat ctgttgcttt
    24901 tttcttgctg ttctttattg tcttgcttgg taacgaagat tgtatcatcg ttaagtcctc
    24961 ctaatatttt ttaatcacca gttaatttta cgccgtactt atgagcaaaa ttttctgctt
    25021 cttttagata tgaattttca aaatcacctg tttgccaata gttatatgca gcggtagtca
    25081 aataagacgt agcatctgaa taagtggctg gtaaaacagt atttgatgta ttttcattga
    25141 ttttattcaa tagttcatag tatttttgtc ctccttagta gtcaaacttt ttctcagctg
    25201 cttctgtttg ataggccaat gagttagatg tagccacgcc cagctccagt gcgttggcta
    25261 agcattcttc atctgtcagc ataaatgtaa gaaattgttg tgccacttgt ggatttttgg
    25321 catctttagg gacataaaaa cttgatcctc ctgatactgc accttttcct ggattttctt
    25381 ttgaaaaagg aatcagtgga gccatgcgcc atttgtcaga tgcatcagga aaattcaaag
    25441 acatattcgt agcataccag ccgccagcaa caaacattgc agattcttga aatgctttct
    25501 cagcatcttg tgcaccgtag aaatgtacaa tatctgagtc gatcatttct ttgattaact
    25561 ttgcagcatg tttcgcttct ttagtattca gacggatatt tccttcttca tcaagcaaag
    25621 attgattctg ctgggctagc atgttgataa acaattcttg gtccccagat tctggcaagg
    25681 caattccaaa actaccagtt ttttctttta atgcttttgc cacctggata tattcttccc
    25741 aagaactgat ttcttcaaaa tctacaccta tttcagcaaa tttttttggt tgataataac
    25801 aaagtgctgg ggtaaaatca ctagcccaag gaataatcgt ttcattactc gtttgttgac
    25861 gcaaaatatt caatttttga tcataaaact gatcgccata tttgtcataa aatccatatt
    25921 catcagcact ataaaaagca tcttgaaatt tttccagcac acctgctgct gaagtgtctg
    25981 ccatggagat aatatccggc atatcttcgt gtgttaccaa ttttggggtg atcatttgta
    26041 ctgttgctgt tcccgaagct acattcacaa tttttaagtc aatatttgct ccagttttgc
    26101 ggttatagat ttttgcagca ttttcaacat agtttgtcag tttgccgttt gcgacatata
    26161 cttctaatgt agtggctttt tttatcattg gatctgcgat gtttgctgtt acttcttcgt
    26221 tagtttttcc acatgcactt aagctgaata atagggtaat gtttagcaaa gctatcacca
    26281 atttgtatct ttttttcatg tctatccctt ctttcttttc aagttcttat ataaaacgct
    26341 ttcacttatg tatattaacg gaattagtaa cacaaatatt tatataaaaa aatattttac
    26401 ttgtcgtttt ggcttttcat ttttgttata atagtcatta attataaata gaaagctttt
    26461 tatataaaaa gagaaaggaa agtggttctt ttgttaacaa acaaccaatc ctccaatctt
    26521 gtcaaaaaaa cactaaccta ttccatagat acccatcttc atttatctgc tgctccctat
    26581 tttcgactac taataaatga aagcgctaat ttatatgctg aatttgcaca taaatctata
    26641 gaactagata atccttccct tttattcatt gataaacagc aagaagtcca aatcttttct
    26701 actcaaaagg aaacacaaac ttttatcatt atccagtttt attttgatga gcaattatta
    26761 gcacatatta cgggacaatc tttttctata gatcaagaaa taacatctat cattactttt
    26821 ctgaaaaatg aacagttcaa aattgattat ctaaaacata gtaagccagc tatttcctat
    26881 gatcaggaaa tcaattcttt tttcatacta tgccaacaga tgagcattca tttgctttcc
    26941 ttattagtta cttattgtct gcaaaaaatt caattgtctt ccttaccaag gcattatcaa
    27001 caggaacttg ctttattgac aataccttca aatgagaaag tcattcctaa aaaaaagcat
    27061 attctttatt cagatgaatt agttgatcca atcatacgat atttagaaga acatctttca
    27121 gaaaattttt tgcttgaaca attagcccaa atttttttta tcagtccagc cagcttaaaa
    27181 aaacatttta gaaaagtgaa tggaaaaagt gttattagct attttaaaga actaaaaatg
    27241 gaaaaagcaa aacgtctcgt gctagaaaat gaattaacct atacagaaat tgcagatata
    27301 ttaggatttc attcgatcca tcatttttct tcagctttta aaaaatatac agggttatcc
    27361 ccttcaaagt attatctatc cttaaaatag aaaaaaattt ttaggtttta tccacaaatt
    27421 atttctctat attttctgtc tattcaaaat aaacaataat tttccggcac aattatttgc
    27481 tgttttttac cataacatag tacgatcaac gtagaaaagg agatgttttt atgaaagttg
    27541 ttgtcattgg cggtgtagct ggcggtcctt catttgccac tcgtttccgt cgattgaatg
    27601 aagcgcacga aatcattatc tatgaacgcg gagaaaatat ttcttatgca agttgtgctt
    27661 tgccttatta tttaggaggt gtgatcactg accgtgactc gctgatcgaa cgtacaccag
    27721 aaatattgaa aacaaaaaac aacatcgatg tctttactaa acacgaagta acagcaatcg
    27781 atccttctac taagcgatta acagttaaag acctatccac aaatgaagaa ataaaaacag
    27841 attacgataa gttgatcatc tcttctggtg ctagaccaga ttatccggat attcccggag
    27901 tttttgaagc agaaaacggc tttgtcctcc gtagtgtgac ggatgcggat cgaatcaaat
    27961 cgttccttga agaaaaaaat ccacaacatg tcgtcattct tggtgcaggt gttatgggtc
    28021 tggaattagc tgagaatttc aagcatcgcg gcttagacgt gactttaatc gatcaattgc
    28081 cacaagtcgc tttcccttat gatccagaaa ttgctaattt agtttatgac aaattgctga
    28141 aagaaggatt agccgttcat ttagaaacaa gagttactga gatccgtgat aaaggtcgag
    28201 aaatagtatt atcagatggc tccgtccttt ctgctgatat gctaattttt gctgttggtg
    28261 tttctccgaa gaatgaagtg gtgaaagcaa ccggcataca attatcagat acaggtcaga
    28321 tcattgttga tgaccagtta caaaccaatc tgccggacat ctatgcgatt ggcgatatta
    28381 tcgaaacgac tagtgtagtg actggtcagc cgatccaaag tatgctttcc agtgcggcca
    28441 atcgtcaagg acatatgctg gcagatattt taaatggtac gcctatgcgc tatcgcggat
    28501 atattggtgc aggtgtcgca aaaatctttg atcatacagc aagttatgcg ggaatgacag
    28561 aacatgaatt aaaagcatca ggcataacaa attataaaac tgtttttatc actccctttg
    28621 accatgccta tttctatcca gaagctacaa gattaaatct aaagctgatt tttgatgcag
    28681 atagcggtcg tattttaggt ggacaagcat ttggagaaaa aggtgtcgat aaacggatgg
    28741 gagaactttc tgtagcaatc accggaaact tgacagtctt tgatttgcct gatttggagt
    28801 tgccttactc tccaccgtat tctactaccc gtgacccgtt gaatatagct ggttatgtcg
    28861 caatcaatca aatgacgaat atcgtagaaa cgatcaaagc aagtgatata cccgaaaacg
    28921 atttgaaaga agcgttcttt ttagatatac gtgaacctaa taaagcacct tctggcagta
    28981 tctcggcaac aaaaaatatt ccaatgaatg agttacgaga tcgaatcaat gaaatcccaa
    29041 aagataaaaa agtttacatt actttcagaa gaggattgaa tacttatact tctgcccgaa
    29101 tcttggcagg tttgggtatc aaagcgattt tgattgaaga ataaaaaaac gaccgcggtg
    29161 ggtagccgcg gtctaggagt tatttttact tgaggagtaa aaatgaaaaa gtatataggg
    29221 ttgttggttg gtatgtatat agaatagaag ataaatgtga agaaattgtg cattatttct
    29281 tcacatttat taggttatag tttaagaaag tttaaacatt gcgcaattta attattttag
    29341 ctgtttcttt tcataaaaaa acatgttgtg actctgagac aaatcatagt ccatagtgat
    29401 gtctctagag taactacgcc taatattacg aggcatcata ttaatctatc agcactagta
    29461 cctaaactag catccctttc gaatattttt tcttatataa taaagtttgc tttcactcct
    29521 ctaatctcac caaatcgact ggcttgcgtt gtgtgatact aggaactgat tggtttagaa
    29581 cgacttttct attgtaatca tatttttcgc catcctcgtt gtcttctaat ccttcaatga
    29641 atgatcccta atgtgtgtat taaataattt aatttttttg ttcctattta ttta
//
LOCUS       DAYYEF010000033        29110 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000033 DAYYEF010000000
VERSION     DAYYEF010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29110
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.033"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1031)
                     /locus_tag="ACHA1B_001664"
     CDS             complement(<1..1031)
                     /locus_tag="ACHA1B_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM8702430.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="ACHA1B_001665"
     CDS             complement(1113..1802)
                     /locus_tag="ACHA1B_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFM8702431.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="ACHA1B_001666"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="ACHA1B_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HFM8702432.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /gene="rplJ"
                     /locus_tag="ACHA1B_001667"
     CDS             complement(2329..2832)
                     /gene="rplJ"
                     /locus_tag="ACHA1B_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HFM8702433.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="ACHA1B_001668"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="ACHA1B_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HFM8702434.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="ACHA1B_001669"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="ACHA1B_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HFM8702435.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="ACHA1B_001670"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="ACHA1B_001670"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HFM8702436.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="ACHA1B_001671"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="ACHA1B_001671"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0006094 - gluconeogenesis [Evidence IEA];
                     GO_process: GO:0006565 - L-serine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HFM8702437.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7544)
                     /locus_tag="ACHA1B_001672"
                     /pseudo
     CDS             complement(6444..7544)
                     /locus_tag="ACHA1B_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
     gene            complement(7636..8523)
                     /locus_tag="ACHA1B_001673"
     CDS             complement(7636..8523)
                     /locus_tag="ACHA1B_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFM8702438.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="ACHA1B_001674"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="ACHA1B_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HFM8702439.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="ACHA1B_001675"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="ACHA1B_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA];
                     GO_process: GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HFM8702440.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="ACHA1B_001676"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="ACHA1B_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HFM8702441.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /gene="cbpA"
                     /locus_tag="ACHA1B_001677"
     CDS             9754..10398
                     /gene="cbpA"
                     /locus_tag="ACHA1B_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-AMP binding protein CbpA"
                     /protein_id="HFM8702442.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="ACHA1B_001678"
     CDS             complement(10454..10957)
                     /locus_tag="ACHA1B_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFM8702443.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="ACHA1B_001679"
     CDS             11554..12519
                     /locus_tag="ACHA1B_001679"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFM8702444.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="ACHA1B_001680"
     CDS             complement(12618..13790)
                     /locus_tag="ACHA1B_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702445.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="ACHA1B_001681"
     CDS             complement(13777..14922)
                     /locus_tag="ACHA1B_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702446.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="ACHA1B_001682"
     CDS             complement(14936..15868)
                     /locus_tag="ACHA1B_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702447.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="ACHA1B_001683"
     CDS             15985..17064
                     /locus_tag="ACHA1B_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0046983 - protein dimerization activity
                     [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFM8702448.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17690
                     /locus_tag="ACHA1B_001684"
     CDS             17061..17690
                     /locus_tag="ACHA1B_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFM8702449.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17800..18027)
                     /locus_tag="ACHA1B_001685"
     CDS             complement(17800..18027)
                     /locus_tag="ACHA1B_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFM8702450.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18130..20718)
                     /locus_tag="ACHA1B_001686"
     CDS             complement(18130..20718)
                     /locus_tag="ACHA1B_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0043139 - 5'-3' DNA helicase activity
                     [Evidence IEA];
                     GO_process: GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HFM8702451.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20738..21397)
                     /locus_tag="ACHA1B_001687"
     CDS             complement(20738..21397)
                     /locus_tag="ACHA1B_001687"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFM8702452.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21446..21949)
                     /gene="trmL"
                     /locus_tag="ACHA1B_001688"
     CDS             complement(21446..21949)
                     /gene="trmL"
                     /locus_tag="ACHA1B_001688"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008175 - tRNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HFM8702453.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22170..23036)
                     /locus_tag="ACHA1B_001689"
     CDS             complement(22170..23036)
                     /locus_tag="ACHA1B_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HFM8702454.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23145..23786
                     /locus_tag="ACHA1B_001690"
     CDS             23145..23786
                     /locus_tag="ACHA1B_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_process: GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HFM8702455.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23848..25209)
                     /gene="mgtE"
                     /locus_tag="ACHA1B_001691"
     CDS             complement(23848..25209)
                     /gene="mgtE"
                     /locus_tag="ACHA1B_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015095 - magnesium ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015693 - magnesium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HFM8702456.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25227..26126)
                     /locus_tag="ACHA1B_001692"
     CDS             complement(25227..26126)
                     /locus_tag="ACHA1B_001692"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFM8702457.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26128..26925)
                     /locus_tag="ACHA1B_001693"
     CDS             complement(26128..26925)
                     /locus_tag="ACHA1B_001693"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003951 - NAD+ kinase activity [Evidence
                     IEA];
                     GO_process: GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HFM8702458.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26903..27607)
                     /locus_tag="ACHA1B_001694"
     CDS             complement(26903..27607)
                     /locus_tag="ACHA1B_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HFM8702459.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27738..28313
                     /locus_tag="ACHA1B_001695"
     CDS             27738..28313
                     /locus_tag="ACHA1B_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HFM8702460.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28431..29108
                     /locus_tag="ACHA1B_001696"
     CDS             28431..29108
                     /locus_tag="ACHA1B_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP adapter SpxH family protein"
                     /protein_id="HFM8702461.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8566 a         6169 c         5232 g         9143 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagg cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctaa ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcta gtcttatacg aaacccatcg tcccgatgtt ttgctgacgg
    17221 acatccgcat gcctaaacaa acgggcatcg atgctgccaa agaaattttg gctaaatttc
    17281 ccaaagccat ccttttgctt ttgacgacat tcaaagatga agaatacatc cgcgaagcat
    17341 tttccatcgg tgtcaaaggg tatttaatca aacagaactt gcaagcgatt attccttctg
    17401 tcaaatccgc ttataatgga caggccgtat ttggtaatga aatcatcgag actttcactc
    17461 aaatgatgaa gaataaaccg acgattgata gtcatgctta tgcttctttt agtgaacgtg
    17521 agcttgcaat catcaaagaa gtagctgccg ggaaaaacaa taaagaaatt gcagatgcct
    17581 tgtacttgag tgacggcact gttcgcaatt acatcagcca attactagaa aagctagatt
    17641 tacgggatcg cacgcaattg gctatctatt tttatcagca tttgcaataa gtcttatcta
    17701 acacaaaaaa acctgaatga tgctccttcg catcattcag gtttttttca catcttctat
    17761 tcaattgtcc cgcaaaccat ttcctcacga ttgaaagaat caaggattcg cagggctgcc
    17821 aggattcgtt ggattgttcg gcgtgttagg cggaaaaata ggcgccttgt ctaacgtttt
    17881 ttctagtttt gattcttcac gatcgtctcg ttctacatca ggactttcat tcaatttgaa
    17941 ttctttttcc atctcatcta actttttaaa gtcattgcca gattcttttg ctaatttcgc
    18001 taatttatct tcggtttctt tagccataaa gtaacgcccc ccttttgatt tcagcttagc
    18061 atatcacact gaaaaaacaa aagaaaacgc taaccaacga tcatttttag ctatttctca
    18121 tctttaaaat caagcatttt ttgccggtat aaaatcgtag ggagaactgt tttccatacc
    18181 aatcatcgga tctactaact ggttatcgat cacttctgct gtaagaacga aatctttaga
    18241 aacagcaggt tctacctctt ctttcttttc ttctccaaca aatgaagaaa acagatctgg
    18301 ttccactgtt tccattactt ggtttttcgt ttcattcgtc ccactgtcat cttctacagg
    18361 tagcttttct tttacaaccc gtggctcttt tgtatagttc ccatcttcaa atggatcatt
    18421 tccgaccaaa gaatcttcat aagctgctag tttggtccgg agagtgatat tcattttatc
    18481 attatccatg atccttgatt tcaacgtagt catccggctt gctgattcat tcgctacaca
    18541 agtgacatag gcttgctctt cccctaacaa aatcaacagt tccttactgc gagtcactgc
    18601 cgtgtagagc aaattacgct gaagcatccg ctgatattga tggaccatgg gcaaaataac
    18661 catcttgaat tcactgcctt gtgatttatg gattgagcaa caataagaaa gagtgatttt
    18721 attccattcg tttcttttat aagtgacctc atttgcatca aactggataa ctaattcatc
    18781 cactttatct tcagaatctt ttgccaagat gatacccgtg atttctccca tatctccatt
    18841 gaatacattc aattcgggag tattgactaa ttggaggact ttgtctccta tccgataaac
    18901 ggtgtcgttc caatgtactt ccttttttcc aggtttccct ggattgaata tctcctgcat
    18961 cattttattt aacgcatcga tccctgcagg tccccgatac attggtgcta atacttggat
    19021 atcttgtgca cggaatccct tatttttcgc tttttccaca attttagaga tcaagggttc
    19081 aatttgataa gcatcacttc ggaaatagga acgatctttt tgattctttg tgaaatcttt
    19141 tggcagacgt ccttctttga tctcatgggc aagaggaata atactagaac catcaccttg
    19201 ccgataaatc tgattgagtt ccattttggg aatttgttcg atttccaaaa gatcatggag
    19261 tacttgacca ggaccgacag agggaagctg atctttgtct cctactaaga taacttgcat
    19321 attcgtcgga atcgctttga ataatgtgtt agccagccat gtatcgacca tagacatctc
    19381 atcaacaatc aaaagtccgc cttctaattc tttcgtactg actgaaggtg ttttttcccg
    19441 tccattcagc cccagaagac gatggatcgt actggcaggc agacctgtcg tttcgttcat
    19501 tcgtttagct gctcggccag ttggtgctgc aagtagaata ggaaaaattt cttgggtata
    19561 ttttgaagga tccaattcca gtccgttcaa ctctgcaaaa agattgacga ttccgttgat
    19621 cacagtagtt ttccccgtac ctggtcctcc tgttaaaata aatagagggg aacggattgc
    19681 ttcagcgata gcttgttctt gcgaaggtcc atactgtatg ccgaatattt tttcgatacg
    19741 ccgaatattc ttctgcactt ctttttcagg ataatggatt tcttttttac gactgagaag
    19801 gcgctggatc gaattaccga tcccccattc agaaaagtac aaactgtttt cgtaaagatt
    19861 agtctcttct tgttgtatct ttccttcttc aacaagttgg ataattacag tagcaacctg
    19921 atcaggctgg atttcaattg ggcgacttgt ttctaaaata cggatcgttt gctgaagcaa
    19981 tgtctccgcc ggtacgtatg tatctcctgt ttgaactgca tgctgaaaaa tctgatgcaa
    20041 gatagctgct cgaattcttc tcggtgaatc tgctgcaata ccgatttgtt cggctagatt
    20101 atctgcacgt ttgaacccga ttccttctat gtcttcgact agctggtacg gattttcttc
    20161 gatgatatcc aaagactcgt tcttataggc ctggtagata ctgaaagcta actgactacc
    20221 gaacccgtaa cgattcagtc ccatgatcac ttgatccatc ccgtggttta gccgaatcgt
    20281 ctcagcaagc atttctcttt ttggcttcgt caaaccggag atttgtttta ataccgaagg
    20341 atcagcaatg attttttcga tagcatcttc tcccagcaat tctacaattt tttctgctgt
    20401 tttcttcccg attcctggga atttttcgct ggaaagatac gctacgatcc catttgcagt
    20461 tgttggcttt tcttgctcat atctttcgag tttaagctgc cttccgtatt taggatgatc
    20521 cactaattct ccataaaaac gataagtctc attttcttga atatcgccga aacttccggt
    20581 gactacaatc tctttttcac ggtaatcagc tgtggtttca ctgatgtgta ccaaaagcac
    20641 tttgtaaaaa ttactaggat tttgaaaaaa aatcgcggca actgtaccaa cgaaataagg
    20701 catttcttct ggctgcatcg gaagccgcct ccttcttcta tagtaaaggt tctggtgctg
    20761 tttcagttcc taaaaaatct gtttggttcc atactttcag ttcatatggc aataatctgc
    20821 aaggctcttc agtctctaaa atcgtcaaac tactattgaa caatccaccc atttcacgca
    20881 actcacttag ctcttttcct gtcatccatt gaatggctgc agttaaagaa gctccatgtc
    20941 ctacgaataa aagtgggcca tctttatgtc gggcaaccgc atctgctaca acagtttcga
    21001 tacgtgtgat tgccgattca atcgtttctc cgtgaaaagg agaaggatca tacagatcta
    21061 aatgattacg caaattcggc agattatccg gatatttctg gtacatttca tcgatcgact
    21121 gaccttctaa agtacccagc cctagttctc ttagcttatc tgtataaaaa atctctaccg
    21181 gacgagcaag ctctttgttg ataccttctg ctgtatcacg tgctcgcttt gctgtactgg
    21241 aataaattgc tttaaaagga acatatttta cctttttccc aaatgctttg atttcttcgt
    21301 aactttgtgg caaaagcgga gaatcgccat tgctcccttg aaaacgtctt tcctgattcc
    21361 attgtgtctt cccatgtcgg gtaaaatata gttccatacg cagcaaactc ctgtctttct
    21421 tttattttac tctataataa actgtctaat ccagcttgtc attttcatag tgatgcgtca
    21481 attctaaatt agggaatcct tgctggcgaa gtgcttcata cactatcatt gcagctgtat
    21541 tcgataaatt caatgagcgg acatgctcat cattcatagg gatgcgtaaa cacttttctt
    21601 cgttttcacg cataaatgtt tctggcaaac cggttgtttc ttttccaaat aaaaagaagt
    21661 gctcttctcc atcagcaaaa ttttcgtcac tatatacttt atgggcaaat tttgagatca
    21721 aatgtagttt acgattacct aaaaatgtta aaaaagcttc taaattactg tggtaagtaa
    21781 tatttacatc attccaataa tccaaccctg cccgttttag atgtttgtca tcagttgaaa
    21841 aacctagtgg ctcgattaaa tgaagcggag tattcgtggc tgcacacgta cgggcaatat
    21901 ttccagtgtt tgcagggatt aatggttcaa ataaaacgat atgattcatc aggatcattc
    21961 ctctcatatt tatgttcgtt tctattttct gacaatttga tttttgcata aaaaaaaacg
    22021 tatcaactcg gtgtcagtca ctgcgagtcg ttacgttagt gaagctcttc tcactaactt
    22081 ttatcagaac aggaacctga taaaaaccaa tgaaaaaaca acttgttgct aatataacac
    22141 cctcaacttt tttttgcaac ctctactcat taaaaactgc tagaaaaacg ttttctctta
    22201 gttcctttta ataattctat gtcaattgta atcttcttca aaggattctt atataagtct
    22261 gctttgattc gctcttctac ctgccattct aaaggtgaca tggccaaaag atctttttga
    22321 ttttcctctg gtatctcaaa ttcataggtt acacgctgac gttcagttaa tttcattgct
    22381 tcagcaaact tggctactac acgttcattg gaataactct gtttttcagg ttgattcgga
    22441 taaaaagcct gacgtagttc ctttaaataa ttttcttgtg gcaccacctt caacacttct
    22501 ccatcttctg agagtacacg ttggaattct tggtaatgag aaggcgaaaa gatatttaaa
    22561 accgcgttga atgtttgatc agcaaacggc aaattggtca aatcagctac acaccaaaat
    22621 gcttcggcag attgttctgt agctgcgtag actccttctt ttgaaatatc aaatccaaca
    22681 gcattttgaa tctttttcaa ttttgaaagt tcattcaaga agctaccttc tccgcagcca
    22741 acatctaata gcgagacttc ttcaggtaaa tgctgcgcaa tagtctcaat aacgggctga
    22801 tacatgccag attggatcat tctacgcctt ggaacgaaca ttccttgatc gtattctgtt
    22861 ttaaccgcat gggataaaaa ataaagtgtt ccttttttgg aaaggtcaaa acggtgatta
    22921 tttttgcata tcaagccatt atcagacttt tttacttctt cttggcaaac cggacagcgg
    22981 aacagctgat gattttctgc caaaaactgg cgtcctcggt caattttttt taacatagtt
    23041 ccccctcatt tctgttttat cttaccgtta gatgctcact ttggcaactg ctaaaaatat
    23101 gatacaatgc ctagaagaaa gtgaaagata aaggagaaga ttagatgatc aaagaatttt
    23161 gcgctgaaaa ctacacatct attcctctag caattgctag aggagccgat cggatcgaat
    23221 tgtgtgacaa cttagcggtc ggtggcacaa ccccgagtac tggtgtgatc gaagaaacgt
    23281 taagttatgc tggggaaaaa gatatccccg taatgacgat tattcgtcct agagggggcg
    23341 acttcgtcta taacgatatc gaattgaaaa tcatgcatac tgatttgatt gaagcaaaga
    23401 aattagggac ggatggcgta gtatttggtt gtcttactcc ttcaggctgg ctagacgaag
    23461 aggccttaga actattgatc gaaacagcag aagggttgca gatcaccttc catatggctt
    23521 ttgacagtat tcctgaagat cggcaattcg aagcaatcga ttggctggta gaacatggtg
    23581 ttgaccgtat cttgactcat ggcggtcctg ctgacaaaac tattgtagaa aatttcccac
    23641 ggcttaaaga attgattgcc tatacagatg gccgcttaat cattttgcct ggtggtggtg
    23701 tcactgcaga gaatgcagca catgtagcta aagaattgaa cgtaagcgaa gtacacggaa
    23761 ccaaaatcgt ggatcttcag ttataatctt ataaacaaaa aaacatttgc aacaggcata
    23821 atgcttattg caaatgtttt tgttttttta cataaaatag cccataaata aagaagcaat
    23881 attgaaataa atcagtacac tcgtcaaatc gctcaaagtc gtgataaagg gaccgcttgc
    23941 tactgctgga tcaaatccta gacgatccat tagcatcggg attaaactac ctgcaagatt
    24001 cgccactgtg attgcaaata gcatagccat ccctatgaca aaccccaaga taaaattatg
    24061 tttccaaaaa cctacgatta gaaaaatcgt gatccccgta acagctcctg tgacaacgcc
    24121 ggtcaagact tcagccaaaa caagtcgaac aaatccatga tctttctcat cagaaatcgc
    24181 aagtcgacga acagccacag ctagcgactg ggttccagca ttaccggcag ttcctgtaat
    24241 cagcgaaatg aagactgcta aaatactcgc ttcacttacc aagtcttcat agtgactgat
    24301 taaagaagcg gtcgacatac ctaaaaacaa cagagtgatc agccaaggca aacgtcgaga
    24361 cgctgccttt actggatttt cattaatttc ttccacattg accccggcaa gtcctgaata
    24421 atcgctagca gcttcatcat caataacgtc gatgatatca tcgactgtga cgattcctaa
    24481 caaatgatca tcataatcgg taacaggaag agctaagaag tcataatctc taaatgtttg
    24541 tgccacatct tcttggtcgt cgcctacatg aactgaaagc actcgttcgc tcatcagatc
    24601 agaaatcatt gcgtcgtcat cattcacgat taggtcgcgc agagaaataa cccctactag
    24661 ctgaccttct tgattaacga catagatgta atagattgtt tcagctacat ctgcttcgtt
    24721 cttcagcacg tacatcgcag agcgaacagt ttgattggct acgatcgaaa caaattcagt
    24781 tgtcatgatc gcgccagccg tttcatcctc gtaatggaga agttccttga tttcactggc
    24841 atcgtctgcc gacatcaaac ttaaatattt agcaatttgc tttttatcca gcgtattaag
    24901 caagtcaaca gcattatctg tatacatctc agaaagcata tcagctgcat agctaggacg
    24961 catttcatct aggtattctt tcatatgttc gttgtcttct tcaatcacat cgaacatatc
    25021 cgctaattct ttaggcgaca gataggaata gatcagctgc ctgttctctt ctgtaagaga
    25081 ttggtagaat tgcccctgct catagatatg catctctaaa aaactgtttc tgaatgcctg
    25141 aatattattt tcccttaaat cttgagtcaa ctgggcaaat ctttcctcta attcttgatt
    25201 ttcatccaaa ccaatctcac ctcgccttat tcttcaaacc gtctcacaac tgcctccatg
    25261 tctgcggcta aaggctgctt gaactccagc aactcttctg taaatggatg gtaaaaacgc
    25321 agatcataac aatgaagggc ttgtcttttt attcccagat ccattcgccc gccatacata
    25381 tcatcaccga gcagggcaca gccaattgcg gaaaaatgaa ctcttatttg atgtgtcctt
    25441 cctgtatgca gctggatatc aactaacgcg atttctgtta gtcgcttctc tatccagtac
    25501 tcagtctgtg ccgaacgtcc ttcatcagag accattcgct tcaatagcga agaataatct
    25561 cgggcgatcg gcaaatcgat atgtccatgt gccgataaat ctgaaagcct tccactgact
    25621 aaggcctgat attttttcac aaacttcttt tcacgaagtt gcatatctaa ttttgcgtgc
    25681 gcaaatccat gctttgcaaa aagcatcaag ccagatgtat cccgatctag tcgcgtcacc
    25741 acatggatta cttggttttc gtaaccttgt tttttataat aagcctttac acgattagcc
    25801 attgtcccat ttggatggta ttgggcagga atagacgaaa cgcctgctgg tttatttact
    25861 accagaacgt gttcatcttc atacacgata tcgatcggtg tttcatccaa aagtacggtt
    25921 tcatgttctc cttcagcagg aatcacaatg gttaccttat catccttagc tagagaaaac
    25981 aagacatttt ctacttgatc attaactttg atttgaccgc cttgaaattt tattttcgct
    26041 aacagaccct ttgagatccc tttttctttt aaaaaatatt ttacttgctg agaatgatct
    26101 ttctcataat cccatgtaaa ctgcatatca atcctcacta ataaaggcat ctttcacacg
    26161 atgccaaaaa tgcatatgtc gataagaagc aaaatggatc cgttcttctg ctattcgata
    26221 ataaattgag cggatatttg cttttgcgac attcaattga tcaaccgtta caagataatc
    26281 ttctgtattt tccaatttta tttctagcca ttcatcatgg gcaatcacga tcggagaacc
    26341 caaagtacga aacactcgat tattcagtga agcaatctct gccaactgaa aggcattgat
    26401 actaggatgg atcacagcac cgccgacact tttattatat gctgtcgaac cagtaggcgt
    26461 agaaatcgtc aatccatctc ctctaaaact ttcaaacagc tcgtttttga tgtatacatc
    26521 ggctaccatc gtacgattgg cccgtttaat cgttgattca ttcagtgcta aaaaatgctg
    26581 gtccggtgtt tcatccaaat aactgatccg aacatccagc aagggataac taacactttg
    26641 ttcccggttc gttcgtaagc tgtctactag ttcttccagc tcgtaatccc gccaatccgt
    26701 gtaaaaccct aaatgacctg tatgcacgcc caagaaacgc acatcattca gacaatgact
    26761 gtagtgatgg aacgccgaca ataatgtgcc gtctccgccg actgagatga ccaattctgg
    26821 ctcatgatca tctcgttgaa tccctgcttg ttctaaaagt gcgttcaaac gttctgtcac
    26881 ttctatagtc tttgcttctt tattatgaac gatcgctact ttcatcccct gcctcctctc
    26941 tttcgctttc tttcttcaaa agcgttcgat agtagacatc atctgatttt cctcttccat
    27001 gggagaataa ccgctgtgct tcttggattt cttcacggat actggacatc tcttcatcca
    27061 actgataggc agcttctgcc gcacgctgaa gtcgttcact catttcttct ggaaaaacgc
    27121 cttgatattt ataattcagc gaatgctcaa tcgttgccca gaaattcatc gcaagagtcc
    27181 gaatctggat ttccgccaaa attttcttct caccgctgat cagctgtaca ggatactcga
    27241 tcaccagatg ataagaacgg tagccacttg cttttttatt tgtgatgtaa tctcgttctt
    27301 ggagaacttt catgtctttt cttttacgga tgatctcaac aacttgatgg atatcttcta
    27361 caaactgaca catgatcctt aacccggcaa tatcagacat ttcttcttct aaacgtccca
    27421 ttggaatatg ccgtaattgt gattttgtta caatactatc gactggcttg actctcccag
    27481 tgacaaattc aatcgggaca tgtcgatttt gttcacggaa ctgtttgcgg atcccccgca
    27541 gtttcacttt caattctgat acagtttgtt catatggtgc taaaaatgct tcccaatctc
    27601 gttccatagc tgatacctct acttcattaa cattcattgt ttattctacc atatatgcaa
    27661 agttttttcg tactcttgat ttatgcattg accaaaaaaa gaaaattagg caaaatagac
    27721 aaaaaggagt cgatcaaatg acacaaatgc ttgaaatcga atataaatct atgctgacaa
    27781 agcaagagta cgagatattc atcgctcact atcaattaac agataaagat ttccgtgtac
    27841 agactaatat ttatttcgat accgttgatg aacagctgaa gaaacaaaat tgtggcctac
    27901 ggatccgttt cgttggtcat caagctgaat atacattaaa aacacctgct gaaaaagggc
    27961 gtctcgaaac aacggatacc tttataacag aagaagcaga agcatttatc ttcgaaaaac
    28021 gtctgcctcg ttcaggcgca gtttttcaaa aactttctga tttgaatatc gatcctgctt
    28081 cattaatcca aaccggaaag cttacaacaa aacgagctga attccctatt gaagaaggac
    28141 ttttagctat tgatgaaagc tggggagaca atctacacga ttttgaactg gaactagagg
    28201 taggggatgc atctgtggga aaaattgctt ttataaattt tttaaaacgt ttttctttac
    28261 cttatcgtcc tgctaagaac aagatccaac gtatgcttga agctaaaaat tagaaacctt
    28321 tcattttcac aaggcacttg agttcatttt tttacttttt tctgttaagt tataggatgt
    28381 gaaagaatct agtcactagt tgtatagaat ctattttggg ggagattcat atgatcgaaa
    28441 tctatttatt tgttaatcct ttaggggaat actgtttcga aatggaacaa cagttattac
    28501 aatttatcga agaagagtac gggacaccat caaaagaaaa gatgcaattt cgctttcttc
    28561 ctttggtcaa tttgcagaca attggggatg tcatgcaaca aaaaggaatt tctcagaaca
    28621 atcttgagga acgtaatcac ttattctcaa tgacttattc tgcagcattg gactgcaaag
    28681 cggcgcagtt tcaaggaaag aaaaaaggcc gccgtttttt gatcaaattg caagaagcag
    28741 tcggctgtaa tgacatacca tattctcaag aacttgctga atccatattt gaagaaatcg
    28801 gcggcgattt gaatatgttt aaagaagatc gtcagtctga cttcgttaaa gaagtattct
    28861 tttctgatca aaaaattgct cgggaaatgg gcatcacaaa acacccttct gcagtcgttt
    28921 acaattatgc ctgcgaccgt gattttggtg ttttagtaga agtaaaaggt acaagtagcc
    28981 tttggagaat cacagagctg tgtaaaacaa cagataactc atatcaagtt tttaatggtg
    29041 aacatttaca tacaaatgat tctcagttcc attcaagaac tagccattta cacttgcttt
    29101 ctaattaaaa
//
LOCUS       DAYYEF010000034        27913 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000034 DAYYEF010000000
VERSION     DAYYEF010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27913
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.035"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(18..716)
                     /locus_tag="ACHA1B_001697"
                     /pseudo
     CDS             complement(18..716)
                     /locus_tag="ACHA1B_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
     gene            795..971
                     /locus_tag="ACHA1B_001698"
                     /pseudo
     CDS             795..971
                     /locus_tag="ACHA1B_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348541.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(1147..1716)
                     /locus_tag="ACHA1B_001699"
     CDS             complement(1147..1716)
                     /locus_tag="ACHA1B_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFM8702462.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1790..3079)
                     /locus_tag="ACHA1B_001700"
     CDS             complement(1790..3079)
                     /locus_tag="ACHA1B_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702463.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            3406..4281
                     /locus_tag="ACHA1B_001701"
     CDS             3406..4281
                     /locus_tag="ACHA1B_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM8702464.1"
                     /translation="MGKRSTIQLMIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGT
                     FSRVQCTPDLLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLE
                     AMAENHATIDNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDD
                     ELLLLLDKFEKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAI
                     QLGISPRGSLSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKK
                     QIIHTLVAQIPIPVR"
     gene            4295..4618
                     /locus_tag="ACHA1B_001702"
     CDS             4295..4618
                     /locus_tag="ACHA1B_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702465.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KNKRF"
     gene            4615..5367
                     /locus_tag="ACHA1B_001703"
     CDS             4615..5367
                     /locus_tag="ACHA1B_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HFM8702466.1"
                     /translation="MILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKR
                     EISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKL
                     SAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPELLILG
                     NRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKD
                     RTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5357..7528
                     /locus_tag="ACHA1B_001704"
                     /pseudo
     CDS             5357..7528
                     /locus_tag="ACHA1B_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7640..9811)
                     /gene="copB"
                     /locus_tag="ACHA1B_001705"
     CDS             complement(7640..9811)
                     /gene="copB"
                     /locus_tag="ACHA1B_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HFM8702467.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9831..12017)
                     /locus_tag="ACHA1B_001706"
     CDS             complement(9831..12017)
                     /locus_tag="ACHA1B_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFM8702468.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(12017..12226)
                     /gene="copZ"
                     /locus_tag="ACHA1B_001707"
     CDS             complement(12017..12226)
                     /gene="copZ"
                     /locus_tag="ACHA1B_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005507 - copper ion binding [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HFM8702469.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12239..12679)
                     /locus_tag="ACHA1B_001708"
     CDS             complement(12239..12679)
                     /locus_tag="ACHA1B_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0006825 - copper ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HFM8702470.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12753..13292)
                     /locus_tag="ACHA1B_001709"
     CDS             complement(12753..13292)
                     /locus_tag="ACHA1B_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HFM8702471.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            complement(13907..15373)
                     /locus_tag="ACHA1B_001710"
     CDS             complement(13907..15373)
                     /locus_tag="ACHA1B_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFM8702472.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(15684..17765)
                     /locus_tag="ACHA1B_001711"
     CDS             complement(15684..17765)
                     /locus_tag="ACHA1B_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0042625 - ATPase-coupled ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFM8702473.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            complement(17907..18029)
                     /locus_tag="ACHA1B_001712"
     CDS             complement(17907..18029)
                     /locus_tag="ACHA1B_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702474.1"
                     /translation="MNLDKLPATGFKLSCYPVKIKKASAGWIRAVAMIEKKKKE"
     gene            complement(18289..18648)
                     /locus_tag="ACHA1B_001713"
     CDS             complement(18289..18648)
                     /locus_tag="ACHA1B_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HFM8702475.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(18678..19019)
                     /locus_tag="ACHA1B_001714"
     CDS             complement(18678..19019)
                     /locus_tag="ACHA1B_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702476.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            complement(19016..19690)
                     /locus_tag="ACHA1B_001715"
     CDS             complement(19016..19690)
                     /locus_tag="ACHA1B_001715"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HFM8702477.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(20743..22041)
                     /gene="asnS"
                     /locus_tag="ACHA1B_001716"
     CDS             complement(20743..22041)
                     /gene="asnS"
                     /locus_tag="ACHA1B_001716"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004816 - asparagine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006421 - asparaginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HFM8702478.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(22081..23271)
                     /locus_tag="ACHA1B_001717"
     CDS             complement(22081..23271)
                     /locus_tag="ACHA1B_001717"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008483 - transaminase activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFM8702479.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(23292..23819)
                     /locus_tag="ACHA1B_001718"
     CDS             complement(23292..23819)
                     /locus_tag="ACHA1B_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HFM8702480.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(23866..26655)
                     /locus_tag="ACHA1B_001719"
     CDS             complement(23866..26655)
                     /locus_tag="ACHA1B_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0006139 - nucleobase-containing compound
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase C-terminal domain-containing protein"
                     /protein_id="HFM8702481.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(26802..27002)
                     /locus_tag="ACHA1B_001720"
     CDS             complement(26802..27002)
                     /locus_tag="ACHA1B_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFM8702482.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(27454..27774)
                     /locus_tag="ACHA1B_001721"
     CDS             complement(27454..27774)
                     /locus_tag="ACHA1B_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702483.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
BASE COUNT         7845 a         5918 c         4904 g         9246 t
ORIGIN      
        1 aaagaggggg ggatttttta tcgttgtgga atatttaaat accaacgctt gtcatgaaaa
       61 tcttgtgctc cacccttagt atttccttct ggatcgtttg tcgcacgcat catgacgtat
      121 actttcttat tagggaaatc acgcatattg aaagatacat gatagccaac atttcctaaa
      181 gtattataag cttgatttac gtctggtcta taaatcccat cagctcttac tctagctagt
      241 tcttttccag tattgtagtc cataatgaaa atatactcgt atttataatt agcaatgtgc
      301 catccagcta catgcaagtt tgcgttttcg atttctccga actgatcaat gtgggcgtaa
      361 tttgttccat ctgtcagcgt agaatttgca gcacctgctc gagttggatc aattactggt
      421 ttatcctccg aagtagttgg attatcatcc gtaaaaccat gagccaaatc ataggctagt
      481 ttttctttac ttacacccat ttcagaaaga taaccgtaag gatctgtatg atcgccccaa
      541 atattttgtg ttacccataa atgcgatttg attcctggtt ggttataagg agtgtctaat
      601 gttaatggaa taccatattt cattgctgaa tctcttgcca attcaacgta tactttatag
      661 ttcttttcaa aagtttcttt atcatgtgtg tgttgtaact cgatttgcac aggacttttg
      721 gctcacgagg ttgtcctact ctacatcttg ctgatagata tgctgaaagg aaaacaccaa
      781 cattatgttt tgctttttca gctagaacga gacaagcagg aataccttta gaagatatca
      841 aagatttttt aggtcataaa gatgtttcca ctacacaagt ctatgcccat atttctcccg
      901 aagtgaaaaa aagatcaatg aatcaactag aaaactatat agaagagcaa ataaaaaagc
      961 actcaaattg agtgcttttt taagctcact atcactaaaa ctatcactaa ttttatttat
     1021 aagcgaacat gtttctatca ctgatttttt aaatctagcg aaaaaccctt atcttaaagg
     1081 cgttcgttca attctttggc aaggtcttca aagcctggct tgcctagaag tgcgaacatg
     1141 gttttcttat agctcatgta gaaaaatttt cttgatgatg attttatcca tcaattgaga
     1201 ttgactgttt tgctctccta tgatttcagc tatgattgtc cgattttgcg gttttcttct
     1261 taactggtag ttgattttcc cagtttccat caactcgcta agcatatcca cgactccgcc
     1321 aaatccggtc tttttcgtaa taaaacctag tgctaccatt cgttcatcta gattttttgc
     1381 tgtaatcgtc acaccagtaa tgagcgagtg ctgtaatgtt tgggccagct cttccatccc
     1441 ttcagcattg gatacgacgg aagctgtttt gttaataggt tcttcgttta tttcttttgg
     1501 ttctttcctc tccactttca ctgtttgacg aaggacatct agttcttgca agagcgtttt
     1561 gtattgttct tgggtcagca tcacgccagc tactttttca cgattaaata tatatacgcc
     1621 agttcccgcg tctcgcgctt gagcaaatac atccatcggc gatcgtttca cttctgtgat
     1681 cgaagatgtg ggaacttcta atttctttaa ttccaatgga tttcctcctt tactaatcgc
     1741 tttttattat agcacagact gacttgtttt gatctttttt ccaaaggttt tatcggtttt
     1801 tgcctaacca gtaattgata tcggtaagaa gtctttcgat accaaatgaa ggatggtaca
     1861 gatacgtttt ttgatcttcg ttatggtcta gtggaaaaaa atgatcggtg atcactagat
     1921 ctgcataccg aggcggctta tttcgagtac atacatgtat agagatccgt tttcgatgtc
     1981 ttagcgtttt gttcagtacc ccagcaagtc ttcttgcttc ttggtgttca tagcgaaaaa
     2041 aaaagacgat tttcacttca ggagggtgga catctaaata ccctcgttcc tggagtgttt
     2101 tcagtaaaag catcccccac tctactgcgg ggtgtgcaag tgcttgttgg atcgctagcc
     2161 gaaattgata tagtttatct ttggaattgg gaaatttttc taatgtttcc tgataataac
     2221 gaacttcttc tatcagccgg tcatggatac caattacgta acgaagccat tcttggtaaa
     2281 gtacttttat cagctttgat ttgctttcgc tctcaaattc gctattcagc caaaacagcg
     2341 aatcaagctt ttcagtcaca atcgtcaatt tccgatagtc ttgtgtctct tctatccgtt
     2401 tccaccgctt ttcagtaatc tggttacagc tcaagcgcaa aattgctaga taattttttt
     2461 cttttattgg caaaatctgc tcctctctaa atagcaattc aggaaacaat tcaaagaata
     2521 gtgttcgact gtctcctaaa atctcgattt ctgccggatc ctttctttgc ttcaataatt
     2581 ggatgaacat ctcagaaaag gactgctctc catcatctgc aaaaaaatgc ggaaaatctt
     2641 tcaaaaagta aaacagcaga tatcttactt ttctttctga accaaagatc tgtgcttttt
     2701 tataagaaaa agaaaggtgg tactcgccaa accactttct caatcgctct tgcgtagaac
     2761 gatcgtactt ctgctcgtaa ggttcattta atagcagatt tttcagtaaa caaaacgggg
     2821 gtgattggat cagaaaaaca aacaagagat aaggttcgct atatccttga tcataaacta
     2881 actgaacggt tttcttatga agaatcagct gaatgggaca gtcgctttcc gccaaacgtt
     2941 tcagatgccg atccactgtt ttaacatcga ttttcagttc ttcagctaaa tcagcttttc
     3001 gccagatcaa atctttcatt agattgatta gtgaaaataa attctgtgca ttttttgata
     3061 atagtttttg ccatctcatc gatcatttct cacctgattt ctaaacatat tgtttgatca
     3121 aaatgagttc actcctaaaa agataaaaaa ctccctttct atttatttaa atacgcaaat
     3181 cttcctcatt attttttatt ttactcaatt taatcgtatt ctcatttcaa aacgaatgta
     3241 ctttaaaaaa acataataag atcactttgc ttgtaggatg tattcccttc cattacaatg
     3301 aaataaatag cgattttatg agaaggtgat gtgaaaatgg aagaaaaaat agaagaatcc
     3361 aaacaaaaaa tcgatcagtt gatataagaa ttagaaaaag cggtcatcgg caaacgttca
     3421 actatccaat tgatgatcgt ggccctatta gcaggtggtc atgtcttatt cgaagatatt
     3481 cccggtgtag gtaaaacgtt actggtcaaa gcactagcaa aagctgtaca gggaaccttc
     3541 agcagagtcc aatgtactcc tgatctgctg cctagtgata ttcttggttt ttccgtatac
     3601 aattcacaat caaaagagtt tgaatttcgt ccgggaccga tctttaccac gatcttgttg
     3661 gcagatgaga tcaatcgtac gactcctcgt actcagtcag cacttttaga agcaatggcc
     3721 gagaatcatg caacgatcga caacaataca taccctctag acaatcattt ttttgtctta
     3781 gctacgcaaa atccaatcga gtacgaagga acatatcctt tgccggaagc acagctcgat
     3841 cgttttttat tccgactaca aatcggttat ccttcttttg atgacgaact tttgctactt
     3901 ttggataaat tcgaaaaagt gttggataac ttaaatgaag tattgaacag ttatgaaata
     3961 gaagaaataa aaacaaatgt ggcgaatgtc tttgtcagtc ccgaagtggc atcttatgcc
     4021 ttgcagttag tgtcagcaac aagaagtcat gctgccatcc agcttggcat cagtccacga
     4081 ggaagccttt cctttattca ggcagcaaaa gcttatgctt taatccatgg gagaaattac
     4141 gtcacgccca aagatttgca ggatttagtt ccttacgtgt tttcccatcg cctgattttt
     4201 tacgatcgtt cattgaagga agacgaaaag aaacaaatca ttcatactct tgttgcacaa
     4261 attcctattc ctgtgaggta gattgaggta gacaatggaa aaaatcaaag attatttcat
     4321 taattttgtg ttatttctgg tatatttcat cattgtgctt tttgctcttg tattcaacaa
     4381 ttctttaggc tggttcttgt tggccttttt tactctttat gtatcatgga gcttgatttc
     4441 attaagcagc tttctaaaga aactttcggt tacttgtaca ttgcagccac tcgtttatcg
     4501 caaaaaaagt atgcaggtta ttttttccat agcaaaaaag agaacttttt ctttacctct
     4561 ccctcgttta caaatcggct tcccagcaat ctttgcagaa aaaaacaaga gattttgatt
     4621 cttacaaata aaccgcaaga agtccaattg ctttggcagc caaaagaaag aggatgccat
     4681 gaaacattaa ctgtcatttt tacagcctat gatagtctag gacttttcag aaaaagtgca
     4741 aaaagagaga tctcttttcc tgtgactgtt ctgcctgctt tttgtaagat tcaagcagaa
     4801 aaattacaga gagttctgga aaaaaaacag cagctgaacg cgtaccaaag aggtcttgat
     4861 tttcgggaac atcgcgctta tcgtccaggt gattctttca accgaatcga ttggaaattg
     4921 tctgctcata ctcaagagtg gttataccgt gaatacgatt atcaagaaga agaatgttct
     4981 cctctttttt gcttttgggg ttcgcccagt ccaaaatttg aacctctgct agacttgtat
     5041 ttttctttat ggcatttgag aaaagaaaag cagccggaac ttctgatatt aggcaaccgc
     5101 gcctttcatg gcaaagaccc cggtcatacc tattttgctt ctttggaagc tggcgatgag
     5161 aaagcttttt tcgcacactt gaaaaaatat gcaaaaaaac aaatcgtcct ctttgttcct
     5221 gagaattctc ctgaagtctc agaagctatt gaaacattgt caaaagatcg aacggcttat
     5281 cttgtttatt tcgtagaaaa acaactcatg gtccaagaaa aagacaagat atgttcattg
     5341 ccaggaggtg aatggattga cgattaaacg ggaaaaatgg ctgcgtggcg tttactcctt
     5401 tgtgatacta agtgtaggtg ctccgatatt tgtagtagct aatcaattgc aaaacagcta
     5461 ccttcttatc ctaactattg gtgtcctatg ccttattgtc tgctgtattc ctaaaaaatg
     5521 ggtacgtttg ctgctttctt tgccagtaat gataggttgt ttgtttttat attttccttc
     5581 gaagacattt tccatattat ggatcttaca gtttttttcg tcagttacag aggaattctt
     5641 ccatctatcc caaggtaaac tttattattt gccagaaaag acagcttttt ttctcataat
     5701 gttgctgatc tatttattta ttacattgac cgtggattac gactattggt acgcaccctt
     5761 tctttctttg atggcttact tcatgatgct taccgttttt cggaaaaaag atttactgta
     5821 cgaaatgatt gcggtagtaa ctgttttgtt cgtgtatctg gcagcaaggc aatttttctc
     5881 catccggttg ttgtcgggaa acactcgatt ccagtcattg actacagttc tgcttatttg
     5941 tttcttaact tttagcgcta tcttgccttt atatcttccg aaagtacacc aatctctcga
     6001 ggaaacgagt gaaccgatcc gagaatatct taatgatgaa gggctttatg acacactcca
     6061 tgagtatcaa ttaaccggaa gtgcaagaac aggcttcagt gagaatgatg aacagcttgg
     6121 tggaccttta tatgataatg gcgaagttgt ttttacagcg aaccaaaaag gaaatggcta
     6181 ttggaagatc gaaaataaaa atcattacac cggttctgga tggatagaag atcaggacgc
     6241 acccatccaa ccaatccaag aattccctgt tgacatcacg agctaccaaa ccgttataga
     6301 agacaaagaa aacattacat tgaccctaaa aaaacaagct ttcttacctt atccttatgg
     6361 aaatactacc ttgactgatt tttcattagc tagtggacaa acgctttact atttgcctga
     6421 aagccagcga ttcattcctg tcccgaatga atcgacacgt tctgcaactt tacaaacaga
     6481 aaggttagtt tttacgagag aagaattaaa aagcagtcag ttaaaagctg atgatttaga
     6541 aaatcagcag acaaatcttc aattgccaaa aagtttgcct aaacgtattg aggacttggc
     6601 ggtcgaattg accaaaaatg aagcaacttt aattcgtaaa gtcgaagctg tctaacagta
     6661 tttaaaaaca agcggaaatt tccgctattc caaaacggat accgggcata ctccgaaaga
     6721 acacgattat gtggattatt tcctctttga ttcaaaagtc ggctattgtg acaacttttc
     6781 aacttctatg gtcgtccttc ttcgaacact tggtatccca gctcgctgga caaaaggttt
     6841 tacaaatggg ctcagaacag gcacagataa tcaagggaat gaggaataca gcattctcaa
     6901 tagtcatgct cattcttggc cagaggtata ctttcctgga tttggctggc ttccatttga
     6961 accaacccct tcatttgcca atccaatggg ttcacaacca gttgctgaaa caaccgaaac
     7021 cgtccagcct gctatcgaac aaccaaatga aagcgaaaat atggcagaaa ctatttccag
     7081 tgagagatct gaggtcattc catcagaaga aacaacactc acaccagctt ataaaatcgt
     7141 cttattcagc cttggagtgt gtttatccgt cttgttgttc tttctattgt tattcagaaa
     7201 atctctgcgc tggacaagtt atcttatcta tcttcatttt tttgcttcta ctaatacgat
     7261 tgcatatcaa aaacttctta accctttgga aacattggta ccgcgcaaac ccgcagaatc
     7321 tttgcaggaa tatagcctgc gaatagaaca agaattcaag ctagatctgc gtttcattcg
     7381 attaactact caatatgaag cagaaatata tggacgacaa gcagatccgg taaaattcga
     7441 taaaaaaacc tatttagaaa taacgcgtat aataagaaaa acggtataca aaaaaattct
     7501 gacaaaaggg agccgcttca aaaaataaga taaaatttct ggagaatcta cttctggaat
     7561 gccgagaacc agctgattga gtatcgatta ctcgaaaaaa aggttgtgac acgttttttg
     7621 tcacaacctt ttttcattat tatttgattt tcaatgtcaa agcatttaga gctacaacta
     7681 ccgtacttaa cgacatcaag acagcaccaa ctgctggact taatatgata ccaattggcg
     7741 caagaattcc ggctgctagc ggaattgcaa gaatattgta acctgccccc caccagaggt
     7801 tctggatcat tttctttcgc gtttgcttgg ctagatcaag aaaatgcaaa atatcttttg
     7861 gatcgctgtt tgtcaatacg acatccgcag aatcgattgc gatatctgtc cctgcaccga
     7921 ttgccatccc gattgaagca cgggctaaac ttggcgcatc attgatccca tcacccacca
     7981 tgattacttt tttcccttgg tcaaggtatt tctggacaac agcttcttta tcatctggta
     8041 ataaaccgcc ataatattct tcgatcccta aataatctgc tactgcttgg gcagcgtttt
     8101 tattgtcacc agtaagcatg acaggagtga tttttctttc tttcaatgtt cggataaatt
     8161 cttttgcttc tgtttttact acgtcaccta aagcaacgat tgcagctaga tgattttcta
     8221 aaatcaggaa gctgatggta tttccttgtt cttggtaagg tttcaataat gcttgttcta
     8281 cgtttaatcc gagacgctca acttcttttt cattaactat tttcacttgt tgttttttga
     8341 ctgttgcctc tagcccgact cctgaaagat tttttagatt ttcagcttga taaggcttga
     8401 tttcatgttc tttcaaataa ttcataatgc caacagccaa tggatgattg gcattcgctt
     8461 ccaaggctcc tagatattga aggatttcat ttttattgaa cgcatcatca agtacttcga
     8521 cacccgttac agtaaatttt ccttctgtta gtgttcctgt tttgtccagc atgatcacat
     8581 ctagatcatt ggcttgctcc agtgcattgc ggtttttcaa aagtaatccg tttttagctg
     8641 ctattgatgt ggagcgagca acaactaatg ggatagctaa acctagagca tgaggacagg
     8701 cgatgataaa gactgttacc atacgttcta atgcattagg aagatctgtc aagaacaacc
     8761 aggcgatgaa tgccaggata cccacaatta atgcgacata aaacagccat tttgccactt
     8821 tgtcagataa tgactctagc ttggattttt ctccttgtgc ttttcgcacc atttccataa
     8881 ccttcgctag ataaccattt tcaccagttc cagttacttc gatttcgatc gttccatccc
     8941 cattgataga accgccaatc actttgtcat tggcttgttt tttgattcct cttgattcgc
     9001 cagtcacagc tgattcgtca acaattgttt cacctttcaa gattacacca tctgttggca
     9061 ttttatcacc agaccggacg atcaaacgat caccttcgtt tacttctttc aatgaaactg
     9121 tctcttcttt tccatctttc gtcaagcgtt tcactgattc tggcagtaat tctgctagtt
     9181 tttgtaaagc attgctggca ttcgacacag cattcatttc aatccagtga cctagtagca
     9241 taataacgat caaagtagcc aattcccaga agaaatccat gacgtgtgta tgtggattga
     9301 gcagatttgc gataaacgaa tagacactat aaatatatgc aactgtaatc cccatcgcga
     9361 tcagtgtcat catagcagga cttttttgtt tcaattccat cttagctcca cttaaaaatg
     9421 gctgaccgcc atagataaat agtatagttg ctaagatcaa tacgagccaa tcagaaccag
     9481 gaaacgttac ttgaaatgga aattccattc ccatcattgg tgaaaaaaga atgattggga
     9541 tagctaggat aagcgatagc caaaattttt gtttgaaatt ccccatgtgc atggaatgat
     9601 ccatgccgcc gtgttcgtga tccatgtgca tcgaatggtc catttgtttg ctgtttgcta
     9661 tatctccatg gttatgtccc atgtgcatgg aatgatccat ctgactatgg tcatgtttca
     9721 tctccatctg tttttcatga gattctgtac tttctttgtt tactacttct tttttatgct
     9781 catgtttttt ctccatatcg ttcccattca tttttactcc atcccttctc ttactttttc
     9841 atgtgtcgat ttaagctcag ggagttcaac aatacactga cggaactaaa cgccatcgct
     9901 cctcctgcaa tgattggatt caaaaagcct agtgcggcaa aaggaatacc aatcgtatta
     9961 tagacaaaag cccagaaaag attttgtttg atttttctca atgtcaacct agacaactcg
    10021 attgtttgtg caatggatgc caaactgcta ttcatcagcg tcacatcggc tgtttccatc
    10081 gcaatgtccg ttccacttcc cattgccata ccgacatcag ctaatgctaa ggccggtgca
    10141 tcattgattc catcgcctgc cataccgact tttttgccat ctttctgaag tttttctacg
    10201 taggctgctt tatcctctgg aagtacttca gcaaagatat gctttggatc aataccaact
    10261 tgtttaccaa tcgtttcggc tgccagtttg ttgtctcctg tcagcataaa aacatctaat
    10321 cctttattct ggagctgctt gattgcttgt ttggcttcta gtttgatttg atcagccacg
    10381 gcaatccacc cgatcacttg cttttcatca gctaaaaaca tgactgtttt tccctgctgt
    10441 tctaattcta acgcgtgttc ttggtattca tcaaatgata ggttcaattc aattaatcgt
    10501 ttacgtgtac ccgcaaaata gcgtactcca ttaatcgtac cgctgatccc agcacctggg
    10561 tgggctgtaa aatcaatcat atcgtatgtt gctgcttctt gcagttttcc gtattccacg
    10621 attgctttac ctagtggatg ttcagaagct tgttctaaag tataaaaaat agataggact
    10681 tcttttgaac cgactagatc tgtaactttg ggctttcctt ctgtaatcgt tccagtttta
    10741 tccaaaacaa tgctgtctaa gtgagcagct gcttctaatg cttctccgcc tttaattaaa
    10801 attccatttc gtgcaccaac acccgttcct accataatag ctgttggggt cgctaaacct
    10861 aatgcacatg gacacgcaat gactaataca gagacactat ggatcaatgc gagttgccaa
    10921 tcaccagtga tcaaacctgt agctatgagc gtgataaacg cgatgactaa tacgatcgga
    10981 acaaaaatcc ctgagatccg atctgcgatt ttttggattg gggctttgct cccttgagca
    11041 tcttccacca tttgaatgat ttgcgctaat actgtctgct tgccgacttg tgtgacttcc
    11101 atgtgtagca gaccattcgt attgattgtc ccgccaaaaa gcgtgtcatc cggattcttt
    11161 tctacaggaa gattttcacc agtaagcata ctttcatcta tcgcactgct tcctgaaata
    11221 attcgaccat ctgctggaat ctgctcacca ggacggatga ctagttgatc accaacgact
    11281 acttcttcaa tcgctaacgt ttcttctttc ccgtttctta tcacttgggc ggtttttgtt
    11341 tgaagagaca tcaattgttt gattgcatta cctgttttcg tttttgctgt atgttccaaa
    11401 tatttgccga gcaaaatcag cgtgatgatc atactgctgc tttcaaaata aagatcttgg
    11461 gggtgtccac ggaaaaatcc gttgtaaatg ctcaatgcaa aggcagccga tgttccaatt
    11521 gctaccaata catccatatt tggtgctttc gtcttgattg catggtacgc acctttataa
    11581 aaacgagcac cgacataaaa ttggacagga gcagacagca ctaactggac gattggaaaa
    11641 tgaaaaaagt gaacaatcgc cgcatggctt cctaacatca tagcaatcat tgacaacatc
    11701 aacggcaaag tcaaaaccgt actcaatata agatcgaata gcattttttt caaatacgct
    11761 tgcttttctt ctgcaatttt ttgtttgtgg gcttcatcgt acaaaattgc accataaccg
    11821 atgttttcta cgctttggat taatttttca gtggtcgtcc cttcatattt gacacttgct
    11881 ttttcagtgg ccaagttgac tgtggcattg accacaccag gttgtccgtt cagctctttt
    11941 tcgatcctag cagaacaatt tgcacaagtc atacctgtaa tgacgaacgt atccattttg
    12001 gtttctgctg ttgccatcaa atcacctctg ctttataacc caatccattg attgcttgac
    12061 aaatcttttc ggattgaact tttgtttcat caaacttgac cgtaccgttt gcttttttca
    12121 aatttacttt cactttttgc acgccgtcaa gtgcgcttac tgtttcttct actcttgctg
    12181 cacaatgatt gcagctcata ccttcgattg aaaattgttg tttcattttt tcttcctcct
    12241 attgatgttg tttacattca cattgacctg ggatacagtt acattcgatc gtatctactg
    12301 gttgcttttg ttccagttgt ttcaaaatct cattgatatc ttcttgagtc aaagtggctt
    12361 cttctactag atccgcaatc gtctctccaa tcctttttgc acagatatgg gaaaaaagat
    12421 tttccgtcgc actgcgaact gtttccatct ccgagacagc tggatgataa atgaattttt
    12481 ttccttcttg ttctgtccag atcacttctt tttttaccaa acgtcccagc aaagttttga
    12541 tcgttgctgg tttccaatcc atcgaatcag ctaagatctg cgtgatttct tgggctgtcg
    12601 tctgtccaag tgtccaaata acacgcatga tctcccactc tgaatcactg atctttactg
    12661 gcgttttgac tttttccatt tatttcacac ctttcgttta caaatgtaat cattagctta
    12721 tgaatacaga ttacgcttgt aaacaaaaac tgtcaattat ttttgctctc tattttcaat
    12781 ttagttaaaa attcttgttt ctctcgtctt gttttaagga tgatcagttt atttcttgca
    12841 ttagctactt ggatcagctg ctgtattttc ggttcattgt tttcttcaaa atgccagata
    12901 aaagataaaa attctaagta ttccctgttt agtttctctg aaaatgattc aggcatatct
    12961 ggccgagatt ttttgtttat ctttcttttt agagaacgcc aaactactcg gtagatggcg
    13021 agataacgcg gcactttaag ccaaatgatc ttatctgctt ctttaatcct ttcctctaat
    13081 gtagaagtat aatttccttc aacaatccat gacggattag ataccataaa cgattgctgt
    13141 tcttgcaaaa accacttttt tgcctgaata ctgtagtctg ttgtatgcca taaaaggtct
    13201 agcggcagta gcggaaagtc ggtgatttct ttgatcttcc ttgcgagggt cgattttccc
    13261 gacccacttt gtccaatcac gatgatcttc attcttctcc ctcacttctc tttggaattt
    13321 ggttcgatca taccacttat aacgccgcaa aaaaacaagg gactgtgaca aaagtcgtgt
    13381 caaagtccct tgtttcgaat aaatggtgtt caatcagctg accttcagca ttaactcaaa
    13441 aaacggcaaa atatgaggag ctattttttc gtttgttcct ctaatactca ggtcaaatcg
    13501 ctgattttac aacctcttcc ttaaacggtg ttctcctgcc aacacctcgg tcacaaggca
    13561 caatagtcaa caaacatgag aagttgtttt ttgaaattgc tccttgtgac tcggagttaa
    13621 acggcaggct cactacctct ttcttaaacg gtgttcaaaa gcttgcatct gcggtaataa
    13681 gcccagcaaa acgaaaaata tgaggggcta tttttgtttg gctgttctta ttacttgatg
    13741 caggacagct ttttcacaac ctctgattca cggtgttcca gaagtagctt ctgcgaaaaa
    13801 caagccgaaa cttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    13861 aagctgacca cttctgtcac aacctcttgt aacaagtatt tctattttaa ggctgaacca
    13921 ctgtttctgg ttcagtgatt tctttgtttt tgtctcgacg agcaattgct ggcaagatca
    13981 tacctaataa gatcaagaca attggtgtga tgatattcgt gaataattgg aaccaccatg
    14041 ctttaggatc agcagtataa tctacttttg gcaccattcc taggatacat gcaaacgcag
    14101 tgaaggcaaa gcaccaagca ccaaagataa aaccgatttt tggattttta acaaatttat
    14161 attcagaatt gaatttctta taagctttat tcaacatcat atatgccaag aacacccata
    14221 ggtaacgcat tggcatgaca actgagttca agttcgtcaa ccattttact aattcattca
    14281 tatctttgat accaaagatc ggcaacaaaa taatgattcc tactagtata cctgtcagaa
    14341 gataaccatt caccaatgta cctttacgat tacgtttacg tagccagttt ggtacaaatt
    14401 ctggatccgc atctgctaac aagattttta gtggtgcatc aattgaaaag gctaatgcgg
    14461 agatttgtcc aatcatgttt gtcaatgcgt aaatgatcat caatgagtta ccgataccat
    14521 agtaattacc taaaatttga aaagcactgt atgccccatt tgccatcaag tctttaggaa
    14581 tattatcgct agcaaacagc atacccattg cgactgagcc taatacagca caaatcccta
    14641 ccattgctgc taagaagatc atccctttag gaaattcctt tgcaggattt cttgtagagt
    14701 tgacataagg ggatattttt tccgctcctc caactgcaaa tactagcatc gaaacggttg
    14761 tgaaataact gaaatcaaat gttggaatat atgttttcac ttgattcata tgtggtgtgg
    14821 caaattccat cgttggattg atgaacggtg ccgttacagc taaaagaata aataagatcg
    14881 acatgacgaa catcgctgtt ccggccagtc cgccaatcac tttcaaagta gaaagtcctt
    14941 ttgttgataa atataaaaag gcaagaaata taataagtga aataactgct accatttgta
    15001 ctgacatcgt atttacgata tttccatttc cttggactgc ccaaccgcca gcaatcagga
    15061 ttgcttgagg cttttgtgcc aaataaggaa tatggacgac ccagtaagtc caagcggcat
    15121 agtatgccag tcgtttatta gatgtcgtat tttcgaccca tgaactgacg cctcctttac
    15181 tatccttgaa ggctgaccct aattgtccaa cgatcaatgc gtatggaata aaataaatgg
    15241 ccaaaatcaa tagccaagag gtgacaactg atactccttg ctgagcatag ttattaacta
    15301 cattccccat gccccaaacc atgttaaatg caattaacgc aacagtaaac cagcgtaatt
    15361 gtttgttgtt cattcgttct ctcctttatg ataaaaattt gttatccaga tgtaatcata
    15421 ttcaattttt aacaaactta caagacagtg ttattttatg tgtgtattct tttatttaat
    15481 acacatcgtt ttttcatatt ttttccatca aaaaaataag ttattttctt ttatttcatt
    15541 taccttattg aatttcaagc tattttgaat tttctgcaaa attaaaaaca ttagttattt
    15601 tataatccta tctattttct ttacattttt cattaagaaa aggatataaa aaaaagagga
    15661 cgttcattcg tcctcttcat tgatcaacgt ttatttttta catgcaagct tcgcatggca
    15721 ttcaaaacag ctaatactgt caccccaaca tctgcaaata ctgcatctcc cattgatgca
    15781 aaaccaaaag cacctaaggc aagtaccaaa atttttatcc caatagcaaa gacaatgttc
    15841 tgtttgacga ttttcaatgt tttctttgct aaatggattg cttctgcaat cttcgatggt
    15901 tgatcattca tgatgactac atctgctgct tcaattgcag catcgcttcc caatccaccc
    15961 attgcgattc ctacatctgc tcttgctagc accggtgcat cgttgattcc atctccgaca
    16021 aatgcggtct ttttattgtt tctttgtaag atttcctcta accgctgcac tttatcttct
    16081 ggaagcaatt cgctatatat cttgtccacg cctacttgct tcccgatatg atcagcaatt
    16141 tttttcgaat cgcccgtcaa catgactgtg ttcttcacac cagccttttt taattgaacc
    16201 aatgcgtcta cggcatcttc tttcaaggta tctgcaataa caagataacc actgtaactt
    16261 tgatcgatcg ctagataaag caatgtaccg atttcttgac ttgaaggaaa agagatttca
    16321 aatctttcca tcaatttgtg attacctgct aatacttgtt tgccatcaac ttcagctaag
    16381 atcccttcac ctgcaaattc ttggatatta gctgttggta aaagcggacc tgcgtagcct
    16441 tctaaaacag attgagcaat cggatgtgta gaaaactgtt ctgcactcgc aacatattgc
    16501 atgaatatct ttggatcgat ttttgtatcg atcgtctgga tcgaaaagtc acctttcgtt
    16561 aatgtgccgg ttttatcgaa taccactgtc tcagtttgtg caagcaactc caagtaattt
    16621 gaacctttta ctaatacacc gattttactt gctcctccga taccgccaaa gaaactaagg
    16681 ggtacggaga tcactaatgc acatggacat gagatcacta aaaatgtcaa tgctcgatag
    16741 atccattcag aaaacgccgc tccagaaaca acaagtggag gtaaaacagc taataaaacg
    16801 gccaatccta caacgactgg tgtgtaatag cgcgcgaatt tagtaatgaa attttcagct
    16861 ggtgcttttt tactgctggc attttctact aattctaata atttgctgat agtagaattt
    16921 tcataagatt tttctacttg aactaaaaat ggtttatttt tattgataaa tccacttaat
    16981 actgtttcac caacatatac agatttaggg actgattctc ctgtaagtgc tgacgtatcg
    17041 actaatgatt ctccttcgat gatcgttcca tctaacggta cacgttcacc aggcttcaca
    17101 agtacaaact gaccgatctg cacgtcttca gggttcacgg tcatcaatcc ttccgtcgtc
    17161 tgcacgtgag ctgtttctgg acggatcgcc atcaattcgc gaatcgattt tcttgaatga
    17221 ctgactgcca atccttggaa atactcgccg atttgataaa atagcatcac tgctacggct
    17281 tctggatatt caccgatcaa catagcgcca atcgtagcaa cagacataag aaaattctca
    17341 tcaaagattt ttcctttgac gatattcatc actgccttct tcactacatc atatcctatc
    17401 agcagataaa tcaataaata ccctatcaag cgaattggtt cattaaaatc aaataatagc
    17461 aataaagcga tacctgcaag ggaaaataaa atccggaaca gcgtatttct ctctttttca
    17521 tttccatgtt cagatacttt ttccttatct atttctgtta ctttgacatc tggttctaat
    17581 tccttcacta ctttttttat ttcttgttca atcgtagcca aatgatcttc ctctgcgtca
    17641 atcgttagtt ttccagaagt gaagtttacc gttgcttcct tgactccatt gatcttctga
    17701 actccttttt cgattttcat tgcacagttc gcacaatcta aaccttctaa tctgtaactt
    17761 ttcattttaa tgacctcctc gcctcaacat atgaatatct cttcataact aattataaat
    17821 gaacggttat tcatatgtca aggtatccga aagaaaaaat gaaaaacatc tgcatcggaa
    17881 aatttcttcc atacagatgt tttggcttat tctttctttt tcttttcgat cattgccact
    17941 gctcttatcc aacccgcact tgccttcttg atcttgacag gatagcaact aagtttgaag
    18001 cctgttgctg gcaatttgtc taaattcatt aatttttcga taggacaata tcttttttca
    18061 atccctgcaa aatgtccttc ccagatattc gaagctccac tacgctttca aaaatataga
    18121 aagagttctt taatgaaaat tatttcaact ttccataaac agtaacccca tataaataaa
    18181 agacgtaaaa gtcacatgga agaacttata caggagaacg catagagtca ggtgaaatac
    18241 atgtatccca cctgactcta tgctttatct aacctttatt attctctttt atacaatttc
    18301 tgcaccgaat ggcatcaacg ccaatcgagc aagtttgaaa gattgcttgg caaaaggtat
    18361 ccctatgatc gtgatacata gaaggatgcc gctgacgaca tgtgcgagag caattggtag
    18421 gcctgaaacg atcagccaga tgatattaac aatcaatgac atgccagact ggtgataaat
    18481 tacttctttg ccaaaaggcg caaaagaaag ggaggcgatc ttaaaacatt gcataccgat
    18541 tgggatacct atgatcgtga tacaccaaag tatccccgct gctaaccagc taagaccacc
    18601 gattagtccg ccgaatataa accagatgac atttcctaaa caactcattg tatttctcct
    18661 tctattactg tttttgatta aaactgggca aaaaatgatt ttattcttct ttttttagct
    18721 tccagtatca aatattctgc aaattttttt tggatttctt ccgtattttc ttttgttact
    18781 aatgtgtgtt ggattagttt tcctgatggt cgctgatcca atcgttcttc tgactgttgc
    18841 acgtccgctt gcgcaaatcc gataatccgt ttttcttttg ttacagcaac gagcaatagt
    18901 ttattcttat catttaggtc agctgccgtt tttgctttta cgaatgattc tggatgatca
    18961 gtaatcagct gattgatttg aggtagatct tcttttactg cccaccgtat ttccatcatt
    19021 tctcactttt ctttcgctca tttttatctc cactaaaaaa atcgactgcg gcaattgcat
    19081 ctatccagct ttgtgcaatg atctcatgtc cgccaatcgt tgggtggacc ccatcttctc
    19141 ttgtatattt cgaaaaacca taaacaatcc ctaaagcatt gaatatacca tctaaaggaa
    19201 ccagcaatgc gccatattcc ttagcaagtt tacgaacaat ttggatttta gggtctaagt
    19261 ctttacgcca gccatgacgg tcgtcggtta taggaagtac aaacggctcc atcaagatga
    19321 tgttgcagat tcccactgtt tgaagttcat ttagtaattt tcgataaacg gattcaaatt
    19381 gctgagcaga tttctcagtt ccgaatatag cctgatcgct agtattatgc caggtatcat
    19441 tgattccgat caaaatcgat acatagtcag gttgtaaagc taaacaatct tcttgccagc
    19501 gtacttgcag atctgcaatt ttgtctcctc ctatcccacg gttcatgcat tcaaattcca
    19561 tcgttggata ttgggagatt agttttccgg caatcaaaag tggataacct ttacctagat
    19621 cagttgcttc tgctcggtct cttcctgcgt ctgtaatgct atcaccgata aataatatac
    19681 gttttttcat ttgtcaaaaa ctcctttttg aataaaacga tgattttctt ccttatatta
    19741 tcccataagc cctatcaaga cgaaagagaa aatatatgta taaaaaatga caccagccta
    19801 gtcccttcaa acaattgaat gaacgctcat caagtgtcta gttttttatg ctattttttt
    19861 cttaacgtgc cggattcccc ttgattcctt cgttgtttgg tccagagaga tcgatcacac
    19921 ctaagcttcc gtcaatcaga ccactgatga cgccatcaga acatatattt ataggctcat
    19981 ctaagacttc tagtaaatgt ccctttacta atatctcttc tagattgctt gggatagatt
    20041 ggtcataact ttatctggtc cgatgatttc aagggtgaat tgaacttaca tatggattat
    20101 tgcatgctga aaatacggac ctactccatc ttcgaatgtt actattagtt tgttttcagg
    20161 tgctagatgc tgctttattt caacagcaga agcatcatca aatcagattt ccatttgaat
    20221 taccttcttt gtaaatgttt gattgattgc gatttcgtta tagaaccttg tgaatcaaat
    20281 agcaatttct tttgctttct tctcttgtct gctggaaact tcctttatcc cgtattttaa
    20341 aaaaagaact gcgagagttc gcagttcttt tttagaataa acggtgctct ccggccaact
    20401 cctcggtcac aagtcacaat agtcatcaaa catgaaaaac tgttttttga aattactcct
    20461 tgtgactcgg agctgaacgg caggcgcaca acctcttcct taaacggtgt tcaaaagcca
    20521 gtttctcggt attaagccaa atttatgcaa aaatgtggaa agccatttcc acaaaatttt
    20581 tcttaatact cgaaactaaa cagctttttc acaacctctc cactaaacgg tattcaaaag
    20641 cttacatctg cggtaataag tcccgccaat tcaaaaacat gaacagctgt ttttgcttgg
    20701 ctgttctaat tacttgatgc agaacagctt tttcatcacc tcttatggat aaattcggtt
    20761 caacaaacgt gggaatggaa tagcttcacg tacatggtcg ataccagcaa tccaagtgac
    20821 tgttcgttca agacctagac caaaaccaga gtgcggaaca gaaccgtatt tacgtagatc
    20881 aagataccat gaatattctt tttcatccaa accgtgatta cggatttgtt ctagcaagaa
    20941 atcatagtct gttgcccgtt cgcttccgcc aataatttca ccgtaacctt ctggtgcgat
    21001 catatctgca cagatcacca cgtcttctct tgttggatgt ggtttcatgt agaatggctt
    21061 gatggctttt ggatagttta ggataaagac aggctgttcg aatgaattcg caatgaacgt
    21121 ttcatgaggt gaaccaaagt cttcgcccca ttcgatgtca tcaaatccat ttttcttcag
    21181 taattcgatc gcatcatcat aagtaatacg agggaatggc aattttgtat aagtttttaa
    21241 gacttctttg tctcgtccta gtacatctaa tgcatattcg caatgatcta aaacattttg
    21301 tactaagaat gctacatatt gttcctgtac ttctaaactt tcttcttgat gagtgaaagc
    21361 catttctggt tcgatcatcc agaattcgat caaatgacgt cgtgtttttg atttttcagc
    21421 acggaaagtc ggaccgaatg aaaagacttt tccgaaagcc atagcagcag cttccatgta
    21481 taattggcca ctttgagata aataagcttt ttgatcaaag taatttgttt cgaatagatc
    21541 cgtagtgcct tctggtgcag aaccagtcaa gatcggcgga tcaattttga caaaatgatg
    21601 ttgattaaag aattcatacg ttgcacgaat gatttcattt ctgatctgca taatcgcatg
    21661 ttgtcttgaa gaacgcagcc ataaatgacg atgatccatc aagaagtctg ttccgtgttc
    21721 ttttggtgtg atcggataat cgtggctctc gcttaccact tccacatttg taattccgat
    21781 ttcataacca aattttgaac gactgtcttc acggatttct ccagttacta acacggatgt
    21841 ttcttggtgt agatttttag ctgtttggaa aacttcttcc gacacttcgc tttttacaac
    21901 tacaccttgg aaaaaggctg ttccgtctct taattgtaaa aatgcgattt ttccgcttga
    21961 tcgcttattt gcgacccaag cgccgattgt tactgtttct cccacatggt ttttcgaatc
    22021 gatgatttga atttgttcca cgtatgactc tccttttata ttccttgaat ttctttagga
    22081 ttaattttga cttttactct caataaattg cttgattctg cgtaccgctt cttctaacgt
    22141 agcgcgatca gtagcataac tcatgcggac attttctggt gccccaaagc cttcgccagt
    22201 cacaagcgct acccctgttt cttctaaaag atcttctacc cattgtgtga cattttcata
    22261 tttacacatg cgtagcgttt cttttacatt aggaaaaaga taaaaagctc cttgtggctt
    22321 ttcaagagaa acacccggca gttctgccac aagcgaatat aacgtattca ggcgttcttc
    22381 aaaggcgttc cgcatttctt ccactgtatc ttgctcgcct ttcaatgctt caacagctgc
    22441 atattgactg actgctgtcg gattactggt tgactgggaa gcaacagcga tcattccatt
    22501 gatgatcaca ggatttccca ccgcataacc aatgcgccag cctgtcatcg catatgtttt
    22561 agacacgccg ttgatgatga tagtctgatt tttgattgct tctgaaatcg ttgcaattgg
    22621 agtaaactca ttgccattat aaactaaacg accataaata tcatcagcaa ctatcaaaat
    22681 atcatttttt actgcccatt caccgattgc ctgcagttca ttcttgctat aaatcattcc
    22741 agtcggattc gatggagaat tgatgattac ggcttttgtt ttttctgaac gtgcttgttc
    22801 tagctgttca acagtaactt tccagctatt ggattcttcc cctttcacaa agacaggaag
    22861 tccttctgcc agttttactt gctcaccgta actgacccag taaggcacag gaatgatgac
    22921 ttcatcttgc gggtcaagga tcgtttggaa aagggtatac aaagcaaatt tcgctccgtc
    22981 tgttacgact gtttgtgaag gttcatagac aagtccatag tttttcttca gataatcaac
    23041 gattgcctgt cgaagctctg ggattcctgc tgttggtgta taatagctag ctttcccgtt
    23101 gcggattgct tcgattgctg cttcttggat gttttctggt gtcgcaaaat ccggttctcc
    23161 cacagtcaaa ctcagcacat ctctgccttt tgcttttaat gccttggcct ttgccgcagc
    23221 tgccaaagtg acagacggtt ctaatcgttt tgttcttttt gataactcca tcccattcat
    23281 tcctttacct tttaaattcc cttgattgtc ttgacttcat ctccagattc aaagccaatc
    23341 aggtaataat tcagtttccc atttgtttct tttcctacta cttcccacac aggctgatca
    23401 tcatacatcc ctaaagcagc tttttcgatt tggatttcag gatgggccgc agcaattgtc
    23461 tgttttgctt cgttttcagt cagtcccttt gtttgatcca atacttttac tttttcacca
    23521 gatttaggaa tgataacggc gatttctttt cctttatcat ttgtacctgt cagtgaaaag
    23581 tatgtcttct ttcgagtaaa ccaataaaaa tgatcggctt cctcaagatt tgcatatttc
    23641 tttgcgattt ctactgcttc tttcttcgcc tgcaccgccg gacgactgga acgcaagtaa
    23701 aaaatcgagc tgatcacgat gaccgctaat aaaaatacga tcaagccaag taacacgcga
    23761 ttaatcgttt tttcctttgt ctgttttttc ttcaagggtc gtcgctcctt tatcttcatt
    23821 ccttttcatt atagcagatt ttaattatga aaaaagacag ctcctctaac ttccttcttc
    23881 atttttcttt aagaattcat ggatgtcctg atagatttcc tccatagcta gctctttgat
    23941 cggtactttt ttcggtaatg catggatgat ccgtgcacca tattttgcag tgactagtct
    24001 tcgatccaaa ataagcaata cgccacgatc tgtctccgtc cttatcaagc gacctaatgc
    24061 ttggcgtaac ttcaaagctg ctttaggtac ggattcctgg taaaaaggat tgatcccctc
    24121 tgattctaaa taagcgttcc tagctttgac catcgggcga agcggattat cgaagggtaa
    24181 acgtgtgact acaacgatct gcaaagcatc cccaggcaaa tctacacctt cccaaaagct
    24241 gtcagcgcca aacaatacgc ttttttctga caaaatgaag cgtttcaaaa gcttctcccg
    24301 gcttccgcca aacccttgag ctagtatttc tcgtcctttt tctagcatag acagatgcat
    24361 tttctgatag accttctgca aaacatcatg agaagtgaat aacacaagta ttggccgatc
    24421 ttcttgttcg atcagacctg taagtgctgt ctctaaataa tcgatatatg cttgattgct
    24481 gacttgatgg acggcaggtg cctcttttgg cacatagatc cttgcctgtt tctcataatc
    24541 ataaggagag gcaatcactt taagaggtgc tgcttcaatg ccaagccgct tagagagata
    24601 gtgtcgatta gggccgatct tcagcgttcc tccaatataa agaatacgat catatcgagg
    24661 ataccaaaca gtcgacggca acatagccgc ttgaaaatca tggagatgaa aaatcatctg
    24721 ctgcgctgtg ttcccaggaa cgaaccaatg gatcaaatga tctcgccagt cttccagcca
    24781 ttgatccatc agcaagtact gcttgtctaa ttgatcaaat aagctatata aacttgctaa
    24841 atcgatccgc atctggtttg tccagctttc ttggataatc tcaaaagtca gacgcatttg
    24901 tgactgtagc tgctggatct cctgataaaa aagctgcagg tgatcaatgg ctgtcccaga
    24961 ttccagtggc agctgatcca acatctcttt tgtcatcatg acttcttctg gatactgtcc
    25021 gttaggttgc ttgccgctca ctaaactcat taatccttct gccatacaaa tctgtgcttc
    25081 gcatagcgca gaaagttctt ctcgataaat cgataaccag cgtaaggctt catgttcttt
    25141 cggtaaatag ctttgtattc ggtcaaacag ctgatttggt tcttctaatt gctggatttg
    25201 tttatggaaa tagttaatac ttaatcgttt gtcatttact ttttcagcga tttccggcaa
    25261 atgatgtact tcatcgatca acaaaaatgg actagctgga agcaatggtt cttttcgctg
    25321 tgtttcttgt attaaaaacg catgattgac aatcaaaaaa ttactttgcc tgattttctt
    25381 ttgcaagaaa cgaacaaagt cttgttcgta aaatgactga tttcttgcta aaaatccaat
    25441 acctctgtgc gcgatatctg caaagaatga atggttcaaa tttgttaaat gtaattcatc
    25501 caaatcaccg gtcttcgttt gcgtcagcca aactaagacc gccatttgat acaaagcata
    25561 ttgtttttgt tctggcggtt ccacaagtgt gcctttaaaa cgctgtaaat caatatagtg
    25621 gcgatagctt ttgataatta caggttgtat gggctgatct agcaattgat tcagcaatgg
    25681 aatgtctttt tctatgatct gctgctgcaa aactagcgaa acggtactga tgacagcggg
    25741 tttttcaggt gtagccaaat aactcaatgg cagcagataa ccgattgttt tacccattcc
    25801 tgtagctgct tcgatcatca aatcttttga ttcatctttt gtgaaatggt cgtagaccgc
    25861 attcatcagt ctgttctgtt cttttcgata catcagtgtt ttaccaaaca ttttttcttt
    25921 tgcttgtttt tttcttggat atgtccgctc gccataatgg acggatgtga atagttccac
    25981 ttcttttttc tgcaaagcta gcccatcgac gatttctaat gagggatcaa gtggctctgg
    26041 tttttctttc atttcttcaa tcacatgata aatgaaacga ctcgtatcca tacctgtgtg
    26101 tctacttaat cgcgcaatct gctctaacgt gatgattggc aattttctca tccgttcttc
    26161 gatcagcaaa agaagttgac ccgtcacttc ggcatcacta tctgcctgat gaggattctc
    26221 atgaataaat ccaaggcttt ctgacaaatc agctaagcga aagcttggtt ccgtcggcaa
    26281 gaaaatttgt gcaagttcta ctgtatcgat gcctggtatc ttcaaactag gaagtccgca
    26341 tcgcatgagt tcatggttca aaaaattata atcaaaataa atattatgcg cgacaaatat
    26401 ggtgtctgcc aaaagattgt aaatcgtttg ggcgacatct tcgaaataag gcgctttttg
    26461 gacgcgttga ttcgtgatcc ctgttaaatg ctggatttgt tttgaaatct tccgccctgg
    26521 atgaatatcg atcgaaaaac gtgaagtgat ccgacctgat tcaatcatga cgcagccaaa
    26581 ttggatgatc cgatcttctt ttggattcgt cccagtcgtt tcgatatcaa cgactgcata
    26641 agttcttggt ttcaaaatat cttcctcttc tcctgcctct aatgttcttt tgaaattata
    26701 ctacaaagtg cagaaaaata ctctcatcgc tttttaaaga aaatagacaa aaacgcccag
    26761 acacgcaaat gtctgggcgt ttatttttta gtataggtta attaagcttt agtaacgttt
    26821 gttgcttgag gtccgcgttg gccttcttca acatcgaaag ttactgcttg gccttcttct
    26881 aaagttttga atccgtcgcc ttggatagct gagaaatgaa cgaatacatc gtttccgttt
    26941 tctgcagtga tgaatccaaa tcctttttct gagttaaacc attttactgt acctgtttcc
    27001 ataataaaaa tcctccttgt gtatcaacac atattttgca attacttgaa tggtgtatat
    27061 ctggaagatg tttatttgaa acaagctacc acagattacc gaacaaaaac tactcctata
    27121 gtatatcata ccgtttacaa aaaagctaga gtttttcgac tttttttatt aaaaaaagtt
    27181 ttctcagcga ttacataaag tgaaaaaccg aacttttttt aaaataaacg acatattgtt
    27241 cagttggtgt ttttttgctc tgatgttctt ctttaaacta aaaaaattat tctttctgac
    27301 tacttatcgg ttctgtttca acggtcgagg ctggggaaga ttctttagta ggtctgatgt
    27361 tctcatggta tttctgatag cctatgacag ttaccagaag aacaaggcaa accaatacga
    27421 tcaacgagat tagtttttct tttttgctca tatctatacc tcataaataa caggatgatg
    27481 tccatcatat ttctgagtat gagtaaaagc aaaagctgca gctgtagaat gtaagaaatg
    27541 ccagcaactt tcataatcac aggtcggaca gtaccaaaag taaccaaatc ttggctgcaa
    27601 agaccgttct tctgtttcag gaatcgcaga atcaagatct gttgtctgta cataaacatt
    27661 tttgtacaga cgtgtgcctg taataggaga ccgctgtgtt tcttcagcaa aaactggctg
    27721 acttgttaaa cttagggata gaaacagcaa acaccataac agtctttttt tcataaagac
    27781 ctccttatcg ataagttttt cccaattaaa atcatatctc aagaacgccc gttattcaca
    27841 ttttgttcat aaatgatgtt ttttgtatca taatcgtcaa aaagaggtcg tgaccacgtc
    27901 acaacctctt ttt
//
LOCUS       DAYYEF010000035        27169 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000035 DAYYEF010000000
VERSION     DAYYEF010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27169
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.036"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..519
                     /locus_tag="ACHA1B_001722"
     CDS             <1..519
                     /locus_tag="ACHA1B_001722"
                     /inference="COORDINATES: protein motif:HMM:NF028094.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFM8702484.1"
                     /translation="VQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESSTTVSDANILANIILDFIFEHDIPFKNGYEILPQNEQYFFYKCLTNRVCCSCGKK
                     NADIHHVDSVGMGNNRKKINNSGRRFMALCRECHTKIHVEGFTTFTTKRKLTAVVLKD
                     SDLKRLGLNIIE"
     gene            512..1042
                     /locus_tag="ACHA1B_001723"
     CDS             512..1042
                     /locus_tag="ACHA1B_001723"
                     /inference="COORDINATES: protein motif:HMM:NF019106.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NUMOD4 domain-containing protein"
                     /protein_id="HFM8702485.1"
                     /translation="MNELWMDIEGYEGVYQVSSLGRVKSNRPNYVINKGYVNKEGFIM
                     KPSDNGKGYQIIFLSGKGFRDRRYVHRLVAFHFLKEAYFEGAEVNHKNGDKSNNTVEN
                     LEWLSSDDNKKHARKNGLTNLKGPSKLTDLQALAIKRLYTNKLMSSGEIMKLFNVSRH
                     TVLNIASGKTFSFLED"
     gene            1147..1977
                     /locus_tag="ACHA1B_001724"
     CDS             1147..1977
                     /locus_tag="ACHA1B_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HFM8702486.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            1994..2845
                     /locus_tag="ACHA1B_001725"
     CDS             1994..2845
                     /locus_tag="ACHA1B_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM8702487.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            2842..3201
                     /locus_tag="ACHA1B_001726"
     CDS             2842..3201
                     /locus_tag="ACHA1B_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HFM8702488.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQA
                     PLILAKKYRNTFKEERF"
     gene            3216..3377
                     /locus_tag="ACHA1B_001727"
     CDS             3216..3377
                     /locus_tag="ACHA1B_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFM8702489.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            3374..3679
                     /locus_tag="ACHA1B_001728"
     CDS             3374..3679
                     /locus_tag="ACHA1B_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702490.1"
                     /translation="MSVDKKATMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            3679..3996
                     /locus_tag="ACHA1B_001729"
     CDS             3679..3996
                     /locus_tag="ACHA1B_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HFM8702491.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVKKYKEILDKYME
                     DSK"
     gene            3993..4388
                     /locus_tag="ACHA1B_001730"
     CDS             3993..4388
                     /locus_tag="ACHA1B_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopX family protein"
                     /protein_id="HFM8702492.1"
                     /translation="MILKYRAWNKKTQSFIDYGDLVLDLRSGKIYAGDIGLVESTIDV
                     TDQIELMQSTGMKDKNGVEIFEGDVVITSKGAIGYVAYLQQEAGFVVVLKKSDYRLGH
                     RNTGESYDVATAHEVIGNIYENSELLEVE"
     gene            4385..4723
                     /locus_tag="ACHA1B_001731"
     CDS             4385..4723
                     /locus_tag="ACHA1B_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702493.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            4720..5088
                     /locus_tag="ACHA1B_001732"
     CDS             4720..5088
                     /locus_tag="ACHA1B_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702494.1"
                     /translation="MNEEIKKSIRYIDRALSQLEPLRIESHKGMSVYPNQYDKMNADL
                     RNAKLALINIKNNKGCQYCKHSEPLNDTSNSNFATAIECEENGYYIATEYDDGDYADN
                     GYSAYIQYCPMCGRKLEVAE"
     gene            5085..5390
                     /locus_tag="ACHA1B_001733"
     CDS             5085..5390
                     /locus_tag="ACHA1B_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702495.1"
                     /translation="MNVQVYLKRNLARFPRSWDTNSHPSEAEEESYLMSANMIEITRD
                     DADEFDKKRSWYSVSNPMYTAVIEDYHISDRFILVDLERPKKRIKQYRRCGFSTKKW"
     gene            5414..5617
                     /locus_tag="ACHA1B_001734"
     CDS             5414..5617
                     /locus_tag="ACHA1B_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HFM8702496.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGVSAEETYKVASQCVAD
                     ASDAIRKFGISILSDDRKWEEKE"
     gene            5614..5910
                     /locus_tag="ACHA1B_001735"
     CDS             5614..5910
                     /locus_tag="ACHA1B_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702497.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMQTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKLLAKSKENLAVVRLVDIELINDK"
     gene            5986..6402
                     /locus_tag="ACHA1B_001736"
     CDS             5986..6402
                     /locus_tag="ACHA1B_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family phage packaging/lysis
                     transcriptional regulator"
                     /protein_id="HFM8702498.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLIQYR"
     gene            7310..7654
                     /locus_tag="ACHA1B_001737"
     CDS             7310..7654
                     /locus_tag="ACHA1B_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFM8702499.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            7659..7940
                     /locus_tag="ACHA1B_001738"
     CDS             7659..7940
                     /locus_tag="ACHA1B_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702500.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            8043..8357
                     /locus_tag="ACHA1B_001739"
     CDS             8043..8357
                     /locus_tag="ACHA1B_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFM8702501.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            8335..10029
                     /locus_tag="ACHA1B_001740"
     CDS             8335..10029
                     /locus_tag="ACHA1B_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFM8702502.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKNR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNANLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            10049..11227
                     /locus_tag="ACHA1B_001741"
     CDS             10049..11227
                     /locus_tag="ACHA1B_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFM8702503.1"
                     /translation="MGIFQKAVGYFTKKATVTLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            11190..11876
                     /locus_tag="ACHA1B_001742"
     CDS             11190..11876
                     /locus_tag="ACHA1B_001742"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0046797 - viral procapsid maturation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head maturation protease, ClpP-related"
                     /protein_id="HFM8702504.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            11876..13036
                     /locus_tag="ACHA1B_001743"
     CDS             11876..13036
                     /locus_tag="ACHA1B_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFM8702505.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            13046..13921
                     /locus_tag="ACHA1B_001744"
     CDS             13046..13921
                     /locus_tag="ACHA1B_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702506.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSNVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            13918..14229
                     /locus_tag="ACHA1B_001745"
     CDS             13918..14229
                     /locus_tag="ACHA1B_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702507.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            14219..14572
                     /locus_tag="ACHA1B_001746"
     CDS             14219..14572
                     /locus_tag="ACHA1B_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFM8702508.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            14562..14963
                     /locus_tag="ACHA1B_001747"
     CDS             14562..14963
                     /locus_tag="ACHA1B_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702509.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            14956..15360
                     /locus_tag="ACHA1B_001748"
     CDS             14956..15360
                     /locus_tag="ACHA1B_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702510.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            15372..15980
                     /locus_tag="ACHA1B_001749"
     CDS             15372..15980
                     /locus_tag="ACHA1B_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFM8702511.1"
                     /translation="MAKTKTVVTTFDNISIKRIAFNFKNAGNAIVTNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            16000..16362
                     /locus_tag="ACHA1B_001750"
     CDS             16000..16362
                     /locus_tag="ACHA1B_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702512.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMSM
                     GKGSMDITVIQGAKAVYVAYRQANMVDYISFDEFIDKWDFDMEVAVAVYSTMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            16365..16547
                     /locus_tag="ACHA1B_001751"
     CDS             16365..16547
                     /locus_tag="ACHA1B_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702513.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            16565..19885
                     /locus_tag="ACHA1B_001752"
     CDS             16565..19885
                     /locus_tag="ACHA1B_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFM8702514.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNDIDKTSKALAQSKGEFKTYESTMKDLDNEQQHLKSSASLVESEYKKWQ
                     ATAGQSATESEKLAKAQEYVGKQSDIAEQKIEVLKKQLDATQKEFGETSTEALEMKTK
                     LNDAEREFEELSNAAKNVDTSTVDDIGKKLDMGNLMEATDHLSVIGDKLIDVGSKSIE
                     AAGKAQAMQAQFKQVFGSLEGEAQDAVEGMAEEFGMLPNTIKPVFIQYTSMFKGLGYD
                     TKEAMELAGDSTQLAADAAAFYDKSMDDASESLNSFIKGNYEGGEQIGLFANDTQMAA
                     YAVKHNLIPATEGAKKASEESLLAVEKAQSKYADAIKKHGEGSLEAREAALKLKDAQD
                     KINEELGPQTQKWSDLDEATKQAVRVQYAEDMQKLAGATGQASRESDGLENQMTRAKQ
                     ALEDFYASLGEDILPVFIKGLQAGAKALQGLAEWWSKLDGPMKNFILALGGILALLST
                     LAPVITAVVTIVGTFGSTVLLPIIGIIAGVAAVIAIVITAFQNWGAITDWFSDLWKKF
                     TDWLGDTWESIKESASSVWDGVKETWSGFVDWVQEIWQGVSDWFGELWSGLVEGASNI
                     WQGVQETWQAFVDWVSNIWNGVKEVWSIIWADIVGIVQIPWTLITSLIQAGINIIVGI
                     FDVAGQLLGAAWQAVWTPISDFLKNTWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNG
                     IWTSISTTASNIWNSISATASSIWNSIKNTITSLVQAAATVIQNIWSTVSSWLGGIWN
                     SISSTASNIWNSVTSSISNAINAAKSAIQSVWNSISSWISGIWNGIKNTALNLWNGIT
                     STISSKVNDGKNAISSGWSNLTGIVSDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKI
                     SSIFDNLNISIPHIPLPHFKLSGEFNPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAG
                     PEAVLPLKRSVLQEIGDRILSSTSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQ
                     QIIDSITKIQNDNASAWR"
     gene            19936..20673
                     /locus_tag="ACHA1B_001753"
     CDS             19936..20673
                     /locus_tag="ACHA1B_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFM8702515.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            20683..22974
                     /locus_tag="ACHA1B_001754"
     CDS             20683..22974
                     /locus_tag="ACHA1B_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail spike protein"
                     /protein_id="HFM8702516.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKSLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYDTAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYINDGDGNSLGIDGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDVDHFIIETSKPNVLVRWNLVAHRL
                     GYEDVRLKEDTAYDSTVLDQKRF"
     gene            22998..25079
                     /locus_tag="ACHA1B_001755"
     CDS             22998..25079
                     /locus_tag="ACHA1B_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702517.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDDQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFLAEIKGRMDSLNKQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLHVMYSNSIDFGGYDYSGNPNLMSKLKSSDFN
                     VGYHGSLTSDNEKLHFTSDGTGSIIMFTRINTPQLASGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANNTTITIDDVGKEITIKGTANVNYQITNLDRFYISVSFSN
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWVGKTSLGKNIANKGTTFPIKSSAY
                     EIYKGNTEEELIIGQTYTITLKGTKPASQTFVAYNYWNVNFGDLKPVEGLTDVWSLTF
                     TPTKLEPGLPKDLRIFQSPKETAGACRIDWLKIEKGDTRTPNIEQYKYRGIGMRDSNN
                     PKDYVWDLEPSYVENNLATDIKVAEITGKANNYTDGKVSEINSQLTASINEVDTTAKD
                     AQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALN
                     GKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYG
                     SAYSFVITYSI"
     gene            25093..25440
                     /locus_tag="ACHA1B_001756"
     CDS             25093..25440
                     /locus_tag="ACHA1B_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702518.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKSGTAVDDIEDVDQLKQLNALLTKQLAISVQEQEKMQQMLAQLTM
                     EVASIKNGGKSNE"
     gene            25433..25573
                     /locus_tag="ACHA1B_001757"
     CDS             25433..25573
                     /locus_tag="ACHA1B_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFM8702519.1"
                     /translation="MNSFPGFENIKQFYDWGCYTDQDLLDYVNMNCLTKDQYKQITGN
                     EI"
     gene            25643..26062
                     /locus_tag="ACHA1B_001758"
     CDS             25643..26062
                     /locus_tag="ACHA1B_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin family protein"
                     /protein_id="HFM8702520.1"
                     /translation="MEKYLNTFSVMTGVIGGTIVGLLGGMDNILHVLIFLVGVDFLTG
                     LAKAWKLKEISSEIGFEGLLKKVLIFVVIAVAVEVQKIVGNSIPLREIVIMFYVANEG
                     ISFLENISVFLPLPDKLKEVFQQIRNDTENKDRGGTK"
     gene            26059..27069
                     /locus_tag="ACHA1B_001759"
     CDS             26059..27069
                     /locus_tag="ACHA1B_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFM8702521.1"
                     /translation="MKKKIFVGAIIALFLLPINAFAYTINNEFNLGANEGSSQVANNQ
                     YILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSYAN
                     ANSPVQIELQHTHDKVTFEKNYKAYVELARDSAMKYGIPLTLETPYNQPGIKSHLWVT
                     QNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAANPTL
                     TDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPD
                     VNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIP
                     KR"
BASE COUNT         9750 a         4069 c         5833 g         7517 t
ORIGIN      
        1 gtacagcaac gaaacttcat ctatgcgctg ataggcgata ttttcatcga tacaggcatg
       61 ccaacggact tctggaagga attcttctac ttccgtttcg aaggtgtcac agggcgcaaa
      121 ataagcctca aagatgaatc gagcacaacc gtaagtgatg ccaatatctt agcgaatatc
      181 atcctagatt tcatctttga gcatgatatt ccgtttaaaa atggatatga aattttgccc
      241 caaaacgaac agtatttctt ttacaaatgc ctcacgaaca gggtgtgctg tagttgcgga
      301 aagaaaaatg ctgatataca tcacgtagac tctgtcggca tgggaaataa ccgaaaaaaa
      361 ataaacaatt ctggtaggcg ctttatggct ctgtgcagag aatgccatac gaaaattcat
      421 gtcgaaggtt ttactacatt tacaactaaa agaaagctta cggcagttgt tctcaaagac
      481 agtgatttaa aaagattggg gttgaatatc attgaatgaa ttatggatgg atatcgaagg
      541 atacgaggga gtatatcaag ttagtagctt aggaagagtt aaatctaatc gccctaacta
      601 tgtaattaat aagggatacg ttaacaaaga aggatttatt atgaaaccat ctgacaatgg
      661 gaaagggtat caaattatct tcttaagcgg caaaggtttt agagatagaa ggtatgtcca
      721 tcggctagta gcttttcact ttttaaaaga agcgtatttc gaaggtgctg aagtcaatca
      781 taagaacgga gataaatcta acaatactgt tgaaaaccta gaatggctca gttctgatga
      841 taataaaaag catgctagaa aaaatggatt aactaacttg aaaggaccat caaaactaac
      901 tgatttgcaa gctttagcta tcaagcgttt atatacaaac aaattgatga gctccggaga
      961 aataatgaaa ctttttaatg tcagcaggca taccgtgctg aatatagctt cagggaagac
     1021 atttagtttc ttggaagatt aagagaaaca caaaataggt gtgactaatt tcaaaaataa
     1081 atatcaaatc aaagggatca agttaaacca ggaaacaatt aaaaagttaa ggataggagg
     1141 ataaatttgg ctgagataag ttggatcaaa cttaaaacta ctatgtttga cgatgaaaaa
     1201 atacgattaa tccaagctgt tcctgagtcg gatgccatca tcgttatatg gattcgatta
     1261 ctagttttag caggaaagac taacgacgat ggtctgatat atatccagag gaacatgcct
     1321 tataccgaag aaatgcttgc tacattgttt ggcaaaaacg taaatacggt tcgcttagcg
     1381 ctaactacat tggcaaattt caacatgatt gatctaagca gtgatggact aattgccatc
     1441 agtaattggg aaaaacatca aaatatcgag ggtatggata aagtaaggct aaaaaatgct
     1501 gaaagaaacc gtaaatacag ggaaagaaag agacaggaac gtctcaaatt ggaaaatgac
     1561 gttagcgtga cgtcacgtga cggtacagat aaagatatag aagaagataa agatatagat
     1621 aaagaagaaa agaaaggtaa gtattctgac gaacacttac gccttgctaa aaagttgcaa
     1681 agtaatttaa ctgaagattt tccaaaagaa atgaacaaag tagatatcga aaaatgggca
     1741 gacacaatca ggttgatgga agaaagagat aaagcatcta tagaagcgat tgagtatgtg
     1801 atcaattggc tacctacaaa tgaattttgg tttggaaata ttagaagtgc taagaaattg
     1861 agagaaaaat ttgagaagct caaattcgaa atcaaagcag acaagaagaa tcataaaaag
     1921 caaagtcaaa aactacagta cagcaatcct agtgaatatg acgacttgcc aatttaaaaa
     1981 ggagatgcat cacatggaaa gcctagcaaa tgctatggag aaactaataa gaagagtatt
     2041 agtgcaaagc ggaaaatgtc cagaatgtag cgaacctttg tatagttggc gagctaaaaa
     2101 taaggatggt tcagaacgtt gtaaaccaac atgcatgagt tgtggttata aagcgttacg
     2161 tgtgaaagag gatatacaga ccgaacggat atataacgat agcttaaaag cacgagcgtt
     2221 gagttttttt caaaatggtt cggtattaac agataaaact ttgtttaaat gcaaaatgga
     2281 aaattatcac gtagtggatc aagaaacaaa aatcgcttta gaaaaagcaa aaagctatac
     2341 gaatgaggtt ctgctgaacc atcctgcaca tttcattcta tcagggaaat caggaagcgg
     2401 aaaaagccac ttatcaatgg ccacagcttg ggaaatactt gagcgctcaa attatgacaa
     2461 gaaaatactt tttataagct atcaagaatt attagagcaa ataaagtttt cttataacaa
     2521 tactgaactg agaaaagaaa ttgaaggatc gcttatagcc gatattaaaa caactgattt
     2581 ggtggttttt gacgatattg gagctgaatt aggtagtggg gtatcaaata gtaggcagtt
     2641 tacaaacaac acgttaaaca cgctcttaga agccagacag aacaaggcaa cgatcatcac
     2701 aacaaactta tctggtcctg aactaagaga agcctacggt gaaagaattg tttctaggat
     2761 atttaagaat tcagaaggtt atgcgctgaa attccaacaa acagcagaca agcgcataaa
     2821 accagtgaaa ggtagtatcg catgaataaa taccgtaata aaaaaactgt tcatcgaggt
     2881 atcaagtttg attctatcgc agaagcagag tattacgatc tagccttgtg gcaagctgaa
     2941 gcaaatggct ggaaagtaaa acttcaggaa agatttgagc tgatgccgaa atttgaacta
     3001 gacggaaaga agtatcgcaa gatcgagtat attcccgact tcacatttta taaaaacggc
     3061 aaacttgtca aagtcgtaga tgtcaaagga atgcagacaa aagactttaa gatcaaggca
     3121 aagttgttct gtcatcaata tcaagcgccg ttgatattag ctaaaaaata tcggaatacg
     3181 ttcaaggaag agcgttttta acgaggtggt ccatcatgac aacagaagaa gtgattcaaa
     3241 tgcgtattcg aaacattcag cgtgaaattg acgatctaga acgaacaaag gcagtgatgg
     3301 tcaatgaaac ggcgagaaag gcaatcgatt tgcacataga gaacttaaga agggaaattc
     3361 gtagattgga ggaatgagcg tggataagaa agcgacaatg aaacgaattg ctgaattaac
     3421 caagtcagaa tcttggcagg aagacaaaga aatagttgca gaagtccaaa agctcggtaa
     3481 atcaatgtgg actgaaaagc ctaaacggaa aacgccgaga aaaattgcaa tctggcatgg
     3541 tgatcgaatt ctagtaacag gtacagctga acagttatct gaaattactg gattaagcaa
     3601 aaacattatc tgggatagag ctaggagctt atggattgat tcaaaaggac gacagtttag
     3661 gtatgtggag gagagataat ggatctcatt acacaataca gtgacatcat cctcaagaaa
     3721 atcatgatga agattcagaa agacaaaaaa tcaaaagaac gagcggaatt agttaagttg
     3781 gaaatggctg aaacaggagc aggagtgcga agtagcaggc attggaaagc agcagcaaac
     3841 attgaatttt attacaacga aattcaaaaa gggttcgatc agatgcgtga gctggatcgg
     3901 caaacaaatt ggagcaagaa acttcatcaa gatcgtttca agtttgtaaa gaaatataaa
     3961 gagatattag acaaatacat ggaggacagc aaatgatact gaagtacagg gcatggaata
     4021 agaaaactca gtcatttatt gattatggtg atttggtttt agatttgaga agcggaaaaa
     4081 tttacgctgg ggacattggg ttagtggaaa gcaccattga tgtgactgac caaattgaac
     4141 tcatgcaatc cacaggaatg aaagataaga atggtgtgga gatatttgaa ggggatgtag
     4201 taattacatc aaaaggagcg attggatatg ttgcgtatct tcaacaagaa gccggctttg
     4261 tagttgtact aaagaaaagt gattatagat taggccatag gaatactggc gaaagttatg
     4321 atgtagcaac tgctcatgaa gtcatcggaa atatatacga gaatagcgag ttattggagg
     4381 tagagtgatt atcttagcta ctgactacat cgattcttta aaagatgaaa atgggaatgt
     4441 cccagcattg ctaaattgtg gaattaaaag caagaataga atcattttgt tacggatatc
     4501 ggctgattta gcaaaatatc tttatctgag caagacagca gtatattaca ctgcggctac
     4561 acgttatcag tacaagggaa aaacaatcag tcaggattat tatgatcgtt taatcagtcc
     4621 tgacatgcat ggaaaatcaa aatcagcgat caagttattt ggcgcaatag agatatatgc
     4681 cgatgatttt ccaaatttat ggttgaagga ggaagcggaa tgaacgagga aataaaaaaa
     4741 tctattcgtt acattgatag agcgttatcg caactcgaac ccttgcgaat tgaaagtcat
     4801 aaaggaatga gtgtctaccc aaatcagtat gacaaaatga acgctgattt acgtaatgca
     4861 aagctggcct taattaacat taaaaataac aaaggctgcc agtattgcaa acacagcgaa
     4921 ccgttgaatg ataccagcaa ctctaacttt gcaactgcaa ttgagtgtga ggaaaatgga
     4981 tactacattg caactgagta tgacgatggc gattatgcag ataatggcta ttctgcttat
     5041 atccaatatt gccctatgtg cggtcgaaaa ttggaggtag cggaatgaat gttcaagttt
     5101 atttaaaaag aaatttggcc aggtttcctc gaagctggga tacaaattcc cacccatccg
     5161 aggcagaaga agagagctat ctaatgtctg ctaacatgat agaaattaca agagatgatg
     5221 cggatgagtt tgataaaaaa agatcatggt actcggtttc gaatccaatg tatacggctg
     5281 taatagaaga ttatcatata tccgacagat ttattctggt tgatctagaa agacctaaga
     5341 aacgaattaa acagtataga cgttgcgggt tttcaacaaa gaaatggtga aaacaaaaca
     5401 gaggtgactc agaatgaaca acagacatcg cagaataaca aaactaagaa aacaggaact
     5461 gaatgtacta aagacaaagt ttgaaaaaga atacggagtt tctgcagaag aaacatataa
     5521 agtggcaagt cagtgtgttg ctgatgcaag tgatgctatt cgtaagtttg gaatttcgat
     5581 attaagtgat gatcgtaaat gggaggaaaa agaatgaaac taaaagacgg attttacgct
     5641 agtagccacg gtatcggcgg tttaatgctg gatatgcaga caaagaaccc taaaacacgt
     5701 aagaaaccaa aattcaaagt cggtgacatg gttcgctgcg aagcagaagg gttcatctat
     5761 ccatttcgtg gatatgtaga acatgtctat aatcactcag cgatcattcg cattgaaaac
     5821 acgatggaat gcgacaagtt attagcgaaa agcaaagaga atttagcagt ggtgagattg
     5881 gtggatattg aactaatcaa tgacaaataa aaaagccgga tcgctccgac taacataata
     5941 aaacagacaa gtttattata tcacataaag gagcggtttg acttgatgca attgttacga
     6001 gaggtagatt tcaaacagac aagatgtaat gcgagagatg tgctgaagaa ctttcggcgt
     6061 ttggagcgta tggcaggtcg ctctttgata gatattaagt cgccgattat aacggatatg
     6121 ccgaaggcgc cgaagcacgg caataaggca gaggacgcga tcattcagat gatggatata
     6181 gaagcagaga gagatgcgat tctagcggct ttgatggctc ttagtctgat tagtcgtcag
     6241 atactctact acagcttctg cgacgtaaat aagcattcta attatgaaat aggtcaattg
     6301 atacgaggat acggagagaa gaatgtagag aagttgaaat ccatcgcatt gattgaattt
     6361 gctgaagcat ataaaaaagg cgtattaatt cagtatcgtt gattttgtag ggtttttgta
     6421 gggatagtgt agggtttttg agcggtttaa cgtgatatta tggtagtgtc gaaagattag
     6481 gaaacaggac ttcgacaaaa taaaatgtaa gggaggaaat ctccctcatc gtttaattaa
     6541 gcttcgatag acagcagcgg aaatattaag aataaggatg tgaattttaa ctccttctaa
     6601 attgttctta ttatctatca tccgttgctg tctattgtca ttatgtcact gtggcggaaa
     6661 gggtagacgc ttaaaaataa ggtcaatacg tcgagggata gccttaacgt tttatgattt
     6721 gaccatgcaa tgttcgattc attgccagtg acttaaggaa cctacggaaa caattcatct
     6781 tatcggatgc cgatgaattg gctgactagt cgggatgcta ctagcagtta gaaggcataa
     6841 aatactagcg cagacgtgcg ccactctcag gtgtaggtta ggagagaaac attagttggg
     6901 gttattagga atacgataac ctgcttgcga caaagctttg tactgtcgcg ttggtcatga
     6961 acagagacgg tattctgttt cagtattcgt tagcaaccga gggatgtggc agtggtgagg
     7021 tgcaggaagt atcagacttg tttgtgtgca agttactatt acatattaga tcactctttg
     7081 agtggtcttt ttattttgcg taaaggaggc acgacgatgt atagaccaca atacttagaa
     7141 cagaagcatg aagtaatcac tgtgcaaaac ggtaacggtg agatagtacg aaagtataga
     7201 agaccaataa agagcgatac atataaacgg aaggaaagca atgaagttat tccattgtat
     7261 ggcaaaagaa tagctaagta ttaaataaga ttgcgaaagg agatgggaca tgaccgagga
     7321 attctataga tggttattac agttgataag agaagatcgt ttggttaagt tctatcagtc
     7381 tcctaaatgg cgcaggctta gagagaaagc gatgaaacga gatcactatg aatgccaaga
     7441 gtgtagaaga ctaggtaagt atcatagagt agagaacgtt catcatataa aggaagtcaa
     7501 ggatagacct gacttagctt tagatttaga taatcttatt tgtttatgtg ttgaacatca
     7561 taatgaagtt catggcagat atcttacagc gttagataaa caagagaaga agatagaaag
     7621 cttcgctaac ttcgatgcaa gtgaaaggtg gtaagtgcat gatcatcaat gacaatggca
     7681 gagagtatga tacagaaaag attgaagagt attcatctta tactcaggga ttaattaaac
     7741 gtttgatata cgttcgctat gtaggtatta gggatctgtt atcagataac tgttgtagta
     7801 aatacaaagt gaatcaagta agagaagcgt tgaataaaga taataacgtc gaaagaataa
     7861 aaaatgtttt tggatatagt attgaagaga ttaattatta cattgacttc gctgaagctt
     7921 tcattccgat ggtgagataa ccccccctta aaataaatcg caaatttttt gggggtgatg
     7981 aaacggaggg ggctgtcagg aaaagagatt ttttcgaact ttatcatgaa aggagggcta
     8041 aaatgtttaa aaacgaattg tctcaaaatc gctacagaga aaaattacgc cgctctttaa
     8101 taagccaatt ggaaagtcag aaaacaaata ttgagccatt cttagataat gttgatcgtt
     8161 atatcagttt atgggaaacg gcgatatcac tggaagaaga tatatccgag aacggcatta
     8221 gactggagaa tggtaaaaag aatgaatcag tagcgttgct tgtttctgtc aacaaacaaa
     8281 tgggattgat gttggataaa cttgccatta ctcctgaatt ggtaggtgaa gcaaatgaat
     8341 caattcctga gttataagca tattgaaaat tggttcaaag ctatagaaga aggcactatc
     8401 aaggtatgca aagagcaatt attgctaaaa aattatctag aagaaagagt ctttactaga
     8461 gaagatattt acttcgataa gcagatggta gaggattcaa tcaatatacc agcacaatac
     8521 tttccattcg aattaattcc gtgggaaaaa tttctacaat gttttattta tggtgttcga
     8581 tggaaaaaag ataaaacact agtgttcaat agatatcttt cattaatggg acgtggtaat
     8641 ggtaaaactg gttttgcttc ttggaacaac ttctttctac taaccgctaa acacggtatt
     8701 aaaaattatg atattgatat ctatgccaat aatgaaagcc aagcaaagac tagttttgat
     8761 gatgtattta aagtaattaa agatcatcct gatttagata aaaaagtatt taaagctacg
     8821 aaggaagtta ttcaaaatat cgctacaaac agcaaacttc gttataacac ggcaaatgct
     8881 agaacaaaag atgggaagcg accaggtgca aaccgctttg atgaaattca cgaaaatgaa
     8941 gattattcaa tgataaatgt ggctacttct ggtggtggta aaaatcgaga ttatagagaa
     9001 ttttatgata caactaatgg tcatgttcgt ggtggtccgc ttgatgacat tatagaagaa
     9061 tcaaaaatga ttctttctgg agaacttgga attgacaagg atggagcaga attttctagt
     9121 ttgtttccat ttatttgtcg cttggataac gataatgaag ttgatgatcc cgacatgtgg
     9181 gaaaaagctt gtccaactat taattacaat gcaaatttaa aacggaaaat gtttcaagaa
     9241 tactctcaaa tgcaacgtaa tgctggttta agacttacgt tcatgaccaa acgaatgaac
     9301 agacctatgg aagatacacg atttgctgtt gcttcatatg atgatgttct gcatacgaaa
     9361 gaaaaagaat ttcctgaaaa aatggatgaa gtgataggaa cagtcgattt tgctgataga
     9421 cgagattttg ccagcgttgg gttgctagga aaatacgata aagatgttta ttttacacaa
     9481 catactttta tccacgaatc agcccttcga ttacaaaaca tcaaacgaga ggttatagat
     9541 atttctatag atcaaggaaa atcacagatc gttcatggaa aaaatataga agctgattat
     9601 attgtaggtt ggtttcttga aatgagtaat aaatattata ttaaaaaaat cgctatggat
     9661 atgtaccgtg caaaaatatt gaagcccgct ttagaagaag caggttttac tgtggaaatt
     9721 gttcgaagcg gatctgttac acatggtatg ttaaaagatc tggttgatga cctttttatt
     9781 aatcaacgtt tattttttgg tgacgatgcg attatgcgtt ggtattgcat gaatgtatat
     9841 gaagagcata tttctaatgg aaatatacgc tatgaaaaaa tagaacctga aactagaaaa
     9901 acggatggct ttttttcatt ccttcatggt ttgaattttt tagatgatat ttatgattct
     9961 gctcctgtaa cagtcacaaa tagctcagta gaaaatacag gaactggatt tactcctcta
    10021 gtattctaac ttgaaaggag gtgagaaagt ggggattttt caaaaggcgg taggatactt
    10081 cacaaaaaaa gcaacggtta ctttagaaga atacttttgt aaattgcaag ttgattttgt
    10141 gtatcgaaaa tttgcgattg aaacttgtat tgatttgatt gcaaatgcga tgagtaaagc
    10201 ggaattcaag tcatatgaag atggaaaaaa taaaaagaat gatctttact ataggctgaa
    10261 tgtagctcct aataagaaaa ataatgcaac agaatttaga aaaaaactga tcaggagatt
    10321 aatattctac aatgaagtat tgatcgtttc tccgtctaat aattctagcg aaatatttat
    10381 tgcggatagt tgggatgtca cagaatatgc attgaaagat gatgtgtttt ctcaagtgca
    10441 aattaacaac atagtccttg atagagaatt tctagaaagt gatgttatct atataaaata
    10501 cgcagatcaa caaattaggc aactagtcga tgcgtattat caagcgtatg ggaaactcat
    10561 ttctagtgcc atgaatgttt acaagcgctc taacgctcgt agatacgtac tgaaagggaa
    10621 tttattccga ccgcaagaca atacaacaca agatcaaatc aataaaatga tgacatcaca
    10681 atttaaggct tttatggaag ctgataatgc aggtgcggta tttcaattac aaaatgagta
    10741 cacattagaa gatttcagcg gaaacttcca aagcaattca agagatataa aaaacttaat
    10801 agacgacatc tttgagatga cagcagcagc gtttcacgtt ccgaaaaacc tactaaaggg
    10861 agacatgagt gggttatcgg atcaagtgga cgctttttta atgttcgaaa tcataccgat
    10921 tgctgaactt attcaggatg cgtttaacgc tagtctctat gaagtagaag aatacttgtc
    10981 agggaatttt gtacgtgtgg atacaactat gatcaagatt actagcttca aagatttggt
    11041 tgacgctatt gatgtaggca ttagaaatgg agtatttaca atcaacgaag gaagagaacg
    11101 cgttggaaat gatcgctctg ataaggcgat ggcagatgaa atatttataa ctaaaaacaa
    11161 tcaacaagta tcgaaaggag gtgaggcgaa tgacgacaat gaaaacattt ctagcagtaa
    11221 agaatgaagg cgcagtaccg caaattttta ttcagggatt tattggttct agttggttct
    11281 ttgaagggaa tactgacaag ggaatcaaaa atattttgga tagtctaggt gatcaagaag
    11341 aaattgaagt agtaattaat tcaaacggtg gagacgtatt tcaagggatt gctattggga
    11401 acttacttaa gtcaaataaa gcaaaagtta acgttgtgat taacggctta gccgctagtg
    11461 ctgcttcaat tatcgcaatg gctggcgata ctataaaaat ctacaacaat gcacaattga
    11521 tgattcaccg cgcttccaca tacggagaag gaaatgtcga tgacttccgt acgattgctg
    11581 accaactgga atcaattgat aaatcggtaa aggcttcata taaaacacga ttcaatggca
    11641 cagatgaagc attgcaagaa cttcttgaaa aagaatcgtt tatggatgca gaaacagctt
    11701 tgagttatgg attggtcgat gaaattatcg atgcagaaaa tagctcaggt actgaagcta
    11761 aaaaagaaca aagcgttgaa gaaattttga atgacgttaa agaaaaaaga gcagaaaaaa
    11821 ttgctgcatt tacagcagca ttaaataaaa catttggaca aggagatgta aaataatgac
    11881 agttaaaaat ttaaaaggtg taacagctgc aagcgaccaa ttgatgaaag cttttaaaga
    11941 tggtaacgaa gaatctttta gcgcagctat ggtaagctta tctaaggaaa ttcaggataa
    12001 aattttagaa gaagcaacag caaaaaatca agatcaatta gtattaatga accgtggtca
    12061 gcgtgtatta actacacaag aaacaaaatt ctataacgaa gtagtgaaaa acgaaggttt
    12121 tgcaggggtc gaagaattag tgccagctac tgtatttgaa cgtgtatttg aagatttaga
    12181 acaatctcat ccactattgc aaaaaattac ttttgttaac acaactggtg taacagaatg
    12241 gattgtgtca cgtggagtca atccagcatg gtggggtaaa ctttgcgaag ctgttaaaaa
    12301 agttttagat aatggctttg atgtaattaa catgaagcag ttcaagctat caggttatat
    12361 tcctgtatgt aaggcaatgc ttgatttagg tccagtatgg ttagatcgtt atgtccgtac
    12421 tgttttagta gaatcattga gaattgcatt agaacaagca attgttgatg gtactggtaa
    12481 agatatgcca gtcggaatga tgcgtgacat gagcaaacaa actagcggag aatatgctga
    12541 aaaaaaagca gaacctatta cagctttaga tgctgtaact atgggcggtt tgatggcgcg
    12601 actatcaaaa ttcaatatcg aaggtgtgaa tgatccgatt tatcgtaatg tgaatccttc
    12661 tgatgtggtc ctaattgtga atccaactga ttactggtct aaagtattcc cagctaagac
    12721 tgtactaact gctaatggag aatacgtaca agtattgcca gtaccagttt cagatttgca
    12781 gtcaacggct gtgccagaag gaaaagcagt tattggggta gcctcagatt acttcatggg
    12841 tgtaggatct acactaaaaa ttgaagcttc agatgaatac cattttgttg aagacgaacg
    12901 catttatcta gctaaacaat atgcaaacgg tcaacctaaa cgtaacgata gtttcattgt
    12961 attagatatt agcgctttgg gaactactac tacaactaca aaaccaacaa ccacaacaac
    13021 tacaacacaa gcgtaggtga tcagaatgaa gtatattctt tgtcagccgg caatcaatcg
    13081 gtttaaatgg gagcttgaag tttgtttaac taatctgaag aaactaggaa tcaaagatat
    13141 cgtattgctt ttcagcagac acgatgatca gattcctatt ttttttgaga aggaatatgg
    13201 tgttgaagtt catgtgtacg atgatctgcg ggacgacaaa gagtatattc cttcgattaa
    13261 accatattta tggtggaaat atttagaaga agatcattcg cgtgaggacg accgatattt
    13321 ctatatcgat tcgaatgtca ttttcaataa aagaattaat ttgcgcaaat tgccttctaa
    13381 agatgatgtt tggtattgta gcgactgctg tagttatcta agtcttgatt atattagaag
    13441 ctgtgaaaac ggagaaaata ttctaaaaga tatggcaaac attgtaaatg ttacagtaga
    13501 atctttggaa actataaaca ctaattcagg aggcgcacag tgggttatta accgtcctaa
    13561 agcgaattat tggaaaaagg tttatctgga ttctaatcgg ctatatcgct accttagagg
    13621 gcaaaaaaca aatatacaaa tctggacagc cgagatgtgg gcacagcttt ggaacatgat
    13681 gtatttcaat attggtccta aagttcacga ggaattagac ttttgttttg ctactgatcc
    13741 aatagaaaaa gttaaagaag taaaaatctt acacaatgct ggagtaacaa caaacgatga
    13801 agatttattt ttcaaaggga gatacgtgac ttctacgcct tttgatgaag atttatcatt
    13861 tgtaaacaag aaaaaatgct cttacgcata tgttaaagca attaaggcgg tggttagatg
    13921 acgcctgaac aagtgactga agaattgcta atagctgtga aggataatat ttacgttacc
    13981 tggaacgaag aagatgagtc aattaaaaag atgatagcta aaaatgctgt ttatcttcaa
    14041 agtaaagtga gtacaacact ttctttttct cctgaaagct tagaatacgg attgctaatc
    14101 gaaagatgta gatacgactg gaatcgtgct ttagatgagt ttgaacaaaa tttcgctagt
    14161 gagttattag gtttcattca acattatgcg ctacaagaat atattgcagg tgatgtgaat
    14221 ggcgaataat cgtagactcg aagaaacatt caacgatggt tggttaaaga ttttgacgca
    14281 aactaccaaa agaaatgaac taggaaaaaa gattggtgta gaagatacag aaatcacttc
    14341 tttaaaattt agaaatcttt ccatgagaga tagtgatata acagctatgg atgcgatggg
    14401 atcgaaatta actaagaaag taaagactcc atttcatcca atcgccaaga aatttaataa
    14461 agatcaatat tttatcgtaa tcgatagtat gcgttacaac gttatctatg ccgattacga
    14521 taatttttat atctattttt atcttgaaag tgtgggtgaa tatggtgatt gataattcta
    14581 aagaaaaaga acgtttaaat aagcaaattt ctgctatcaa aacttcctta gaagagcatt
    14641 ttggcctcaa actctttcaa gactccgtag gcgaggatga gctacctgat gattttaatt
    14701 acttcattct cgaaacagga gaaatagaaa tgatcactga gccaaaatat agcgtgggtc
    14761 aaaatctata tctaactttc tattcagaaa atagagaaga tttaacagga gactcactag
    14821 atattatttc attgattcaa aatcgttcga ttcgttttca gagaatggat cccaatcatt
    14881 taaaactaga gaaccaagat cgctatatcg atcaattggt atttacgttt agacgattat
    14941 tgaagagtga ttgtcatggc taaaaatagt tgggagctaa aaataaatgg acatgatgaa
    15001 cttcttgtgc ggatggaacg ctattcaagc gagagcgaac gactgattaa cgaagcattg
    15061 aaatcaaaag gttcggctat tgcagtggat aggattacag aaaaaattcc tgtttctgaa
    15121 gcagatttaa gaagagggca ccaacacgca aaaaatagtc gtccacttaa gactcaatac
    15181 attaatttgg gtttcatcat tagacctaca agaaaatttg agtatttaaa atatcctgat
    15241 ttggggatag gtacttctaa aagaaatcag ccggacgaat ttatgagaag aggattaggt
    15301 cttgcacttg atccaattac agaacttctg attcgtcaat tcgataaatt aaataaatag
    15361 ggggaacaac aatggctaaa acaaaaactg tagtaacaac gttcgataac ataagtatca
    15421 aacgaattgc ttttaatttt aagaacgcag gaaatgcaat cgtaacgaat tgtaatggac
    15481 aattagatgg cgaaacagaa atgcaaacgg tggttaaaaa atgtggagcg acagaagtaa
    15541 aatcaaaatc taaaccaatc aatatgacgg taacaattac tgcacatgta ccgatggaag
    15601 tttatcgacg tttcaatggg ttgaaacaag atggacgtat taaaccaggc atttactctt
    15661 acggtcctga ttccgtaggc gaagatttct cacttgctgc agagatcgtg gatgacttcg
    15721 aagaaaatag aaagttagtt ggtatgttag catgcacttc gaatacagga ttaacattct
    15781 ctattgaaaa tggtgcggat gaagtagctg cgttagaact agaaacaaaa gttatgcaag
    15841 atgaatttgg taaattttat catgaagcaa ttgttgcaga acttgaagaa gacttaacag
    15901 atcaatggat gacgaatcta tctgctgatg tgattaaaaa aacttcagtt gtgacaacta
    15961 cggccactca atcacagtaa aaaaaacgga ggtagcgaaa tgaacgaaga ttactcaaaa
    16021 attgaactaa acgatggaac aattttgaat ttagaaccta aactgaatat caagaaatta
    16081 ttgatgatca atagagattt taacacagac gagtttgcaa aaatgtcgat gggaaaaggc
    16141 tctatggata ttacagttat tcaaggtgca aaagccgtat atgtagctta tcgtcaagcg
    16201 aacatggtcg attacatttc attcgatgaa tttatagata aatgggattt tgatatggag
    16261 gttgcagtag ctgtatacag tactatgatg ttcaaacaag cacgtgatgc ctatcaaaaa
    16321 gaattcgaaa aagcaaataa ggaaaaaaag cttcaaaagt aaaaatgcca aagctcttag
    16381 ttgaaacgtg ggtcgatgtc tattcgatgt tgaccgacgt tttttctatg ccttcagatt
    16441 tggttttaag cgatatctgt ttagatgaca ttttgcaaat ggcttacaac aagagcgctt
    16501 atgaaggatg gaagaactat gcaataaatc aatcccagaa aaactaaagg aaaggaggta
    16561 aaaaatggct aaaaagagaa cggaagcaga agtaactttc atagctaacg atgacggatt
    16621 gaaatctacg ttaaaagaaa tcagtgctga attaactaaa aatagagcag aattaaaact
    16681 agaacaagct caattacaac agactggttc tgaatcagac aagttaggaa gtaaattatc
    16741 ttctttagaa aagcagtatg aattacaaag tcaaaaagtt gaagtaacta gtcaacgttt
    16801 agccaatgcc aaaaaatatt atggagaaaa ttccaccgaa gttcagaaac ttgaaagaga
    16861 actgattaat caacaaacag ctcagcaaag gttatctaat gatatagata aaacgagtaa
    16921 ggcattggct caatctaaag gtgaatttaa aacgtatgag tcaactatga aagacttaga
    16981 taatgagcaa caacatctaa agtcaagcgc atcattagta gaatccgaat ataaaaaatg
    17041 gcaagcaact gctggccagt ctgctacaga atctgaaaaa ttagcaaaag cacaagaata
    17101 tgtcggcaaa cagagtgata ttgctgaaca aaaaatcgaa gtgctaaaaa aacaattaga
    17161 tgccacacaa aaagaatttg gagaaacatc taccgaagct ttagaaatga aaactaagct
    17221 taatgatgcg gaaagagaat tcgaagaatt aagtaatgct gctaaaaacg ttgatacctc
    17281 cacagtagat gatatcggca aaaaacttga tatgggtaat ttaatggaag ctactgatca
    17341 cttgtcagtg atcggagata agcttattga tgtaggtagt aagtctattg aagcagctgg
    17401 aaaagcacaa gctatgcagg cccaatttaa acaagtcttt ggctctttag aaggggaagc
    17461 acaggacgcc gttgagggaa tggctgaaga atttggaatg ttaccaaata cgatcaagcc
    17521 tgtttttata caatatacgt caatgtttaa aggacttgga tatgatacca aagaagctat
    17581 ggagttagct ggtgatagta ctcagttagc agcagatgca gcagcttttt acgataagtc
    17641 tatggatgat gctagtgaat ctcttaattc atttataaaa gggaactacg aaggtgggga
    17701 gcaaataggt ttatttgcta atgatactca aatggcagct tatgctgtta agcataattt
    17761 gataccagcg actgaaggag caaaaaaagc cagtgaagag tcattgttag ctgttgaaaa
    17821 agcacaatct aagtatgctg atgctattaa gaaacatggt gaaggatctt tagaagcaag
    17881 agaggctgct ttaaaactta aagatgcgca agataaaata aatgaagaat taggcccaca
    17941 aacgcaaaaa tggtctgatt tagatgaggc taccaagcaa gcagttcgag ttcaatatgc
    18001 tgaagatatg caaaaattag ccggtgctac aggtcaggct agtagggagt ctgatggttt
    18061 agaaaaccaa atgacaagag caaagcaagc gttagaagat ttttatgcct cattgggtga
    18121 agatatactg cctgtgttta tcaaagggtt gcaagcagga gcgaaagctt tgcaaggatt
    18181 agccgaatgg tggagtaaac ttgatgggcc aatgaaaaat ttcattttag ctcttggagg
    18241 aattctagca ttattaagca cattagctcc tgttataacc gcagttgtta cgatagttgg
    18301 cacatttggt tctacagttt tgctgccaat aataggaatt atagcgggcg ttgcagctgt
    18361 aatagcgatt gtaattacag cgtttcaaaa ctggggcgca atcactgact ggtttagtga
    18421 tttatggaaa aaatttaccg attggttagg tgatacctgg gaaagtataa aagaaagtgc
    18481 ctcatcagtt tgggatggag tcaaagaaac ctggtctgga tttgtagatt gggttcaaga
    18541 aatttggcaa ggagtttctg attggtttgg agagttatgg agcggattag ttgaaggagc
    18601 ttccaacatc tggcaaggag tccaagagac ttggcaagca ttcgttgatt gggtttcaaa
    18661 tatttggaac ggagtcaaag aagtatggtc gattatttgg gcagacattg taggaattgt
    18721 tcaaatacca tggacattaa taacgtcatt gattcaagct ggtattaata ttatcgtggg
    18781 tatctttgat gtagctggac agttattagg cgcagcttgg caagctgttt ggacacctat
    18841 ttctgatttc cttaaaaata cttgggatac tatgacacaa tggataagca tcgcttggaa
    18901 tggaattgta actacattcc atactatatt tgatccagta gtggcatggt ggaatggtat
    18961 atggacatct attagtacta cggcttcaaa tatttggaat tcaattagtg caacagcttc
    19021 tagtatttgg aacagtatca agaatacaat cactagcttg gtacaagcag ctgctacagt
    19081 aattcaaaat atttggtcaa ctgtatctag ttggttaggt ggaatttgga attcaatcag
    19141 ctctacagca tcaaatatct ggaatagtgt gactagtagt ataagcaatg ctataaacgc
    19201 agctaaaagt gccattcaaa gtgtttggaa tagtatatct tcgtggatca gcggaatttg
    19261 gaacggtatc aaaaacactg ctttgaatct ttggaatgga attacaagca ctattagctc
    19321 taaagtaaac gatggaaaaa atgcaatttc aagcggttgg tccaatctaa caggtattgt
    19381 ttccgacata ttcaataatg ttaaaagtac aattgctaac atttgggaag gtatcaaaaa
    19441 gactgttagc gctccaattg attggatcag agataaaatc agtagtatct ttgataattt
    19501 gaatatttct ataccacata ttccgttacc acattttaaa ttgagcggag aattcaatcc
    19561 attgaagggg aaaatcccaa cgttgggtgt tgattggtat gcgaaaggta gtgtgtttaa
    19621 ttctccgaat attatcggtg tcggcgaagc aggacctgaa gcagttttac ctttgaaaag
    19681 atctgtgctg caagaaattg gtgatcgtat cttgagtagc acatcagttt catctagggc
    19741 acaaacgatt caacctgtga ataactacga attcaatttc acaattgatg gtaacgcaga
    19801 tgaggttact atgaagcaaa caactcaaca aatcattgat agcattacaa aaattcaaaa
    19861 tgataatgct tcggcatggc gttaaacagg agagtatttc tcctgttttt ttagtattaa
    19921 aaaggatgtg aaaaaatgac tgattgtata cattctataa tcgatggatt tcctgattat
    19981 ttgcataaat tggctttagc tgaaagacca accatacctt ctccaaaaag acagagagtt
    20041 gaaacttctg ttttaggtag gttaggtggc ttagtacaag attactcgtt tgaagatatg
    20101 tcgtttacat tgcactataa ctatttagag gatgtggaag accatcaagc gttcaagcaa
    20161 tcgttttata tcatgcgtca ttggttaaac tatgcaaaga aattagaatt ctctgacgat
    20221 cccaacgtct attacgttat ccagactatc gatattgggg atgcagaaaa cgatattgtt
    20281 gaatggggag agttcgatgt aaatattact gcgaaaccat tcgcaagagt tcaagaagat
    20341 gtacctataa ccgtagataa accacagtca tttaacttgc tgaataatag tttagaagaa
    20401 agttttccaa agattatcat cactccttca gctacttcat gccagttcat cttaaatgat
    20461 tatgtgttta gtttcgaagg cttagtagca ggaactgatg tagtcattga tagtgatttg
    20521 atgctttgct acgaagagca atcggacgga gatattttag atcggtccaa caaaatgaag
    20581 accatgcaat atccaacgtt gcaagtggat attaatcatt ttaattgtac tggtttgagc
    20641 aaaatacaaa tttatcgtaa cgggttaagg taggtgaaat agatgatcga taatttaata
    20701 actatttacg ataaaaatga cgcgaataat ttagctgaac atttatatga tacgcaaggt
    20761 ttaggcgctt tgtcagactg gttaacagct actgttagca ataaactaaa cggagccgag
    20821 atatttcagg gtacttattc aataaacgga actaatgcag atttgattgt agaaggacgt
    20881 attattcagt gttatgtaga tgaaaatcga gcaaaacagc gtctacggat ttattatgca
    20941 aaaacttctg taataggcaa tacgatagaa gtaaaagctg aacctatttt caatgatata
    21001 agaaaatcgg tgttgaataa atatgacagc ggaacagaaa agatcactgc tactcaggca
    21061 tggcaaaacg caaaagtttt agcgaaacca gctatccctt cgcagttttc tttctcgtca
    21121 ttagtagata cgcttgctaa tgtgaagata gaaaaggcga attttttaga attctttggt
    21181 ggaaaagagg gatctattct agatcgattt catggtgagt ttctaaaaga taataacaca
    21241 ttacgtcatg aaaaaagtct aggtacggat cataaaatca aagcgattta tactaaaaac
    21301 ttaactggtc ttgacttaga gattgatgct caaagtgttt tagttggagt ttatccattc
    21361 attagcagct cttcagaagg agaagacgag atcactctac cagaagaagt tattttcacg
    21421 gattacgtgg atgattatcc tgctggatat gtttcttttg ttgattttaa agacaaagcg
    21481 actgatgtag ccacattaag ggaagctgct aaagactggt tgaaaacaaa catagataaa
    21541 caaaaaccac aagtgagtgg ttcgattgaa ttagtaccat tgaggcatca aagaggctat
    21601 gaaaaatttg ttgatctaga aaaagtttcg atgggtgacg gagtagatgt gtatcatcca
    21661 cagttaaaag tgaatatgtc agcgagaatt gtggaatata cgtttaatgt tctaaccaat
    21721 tcatacgata aattagttgt aggaaacgtc aaaacaaact tcttagaaaa cacagagaat
    21781 aatgtcagca atttgattaa tgatgccatt gatcaattga aaaatggtgg cgaaatcagt
    21841 gatttaatca atgatattgt agatcatcaa actgatatga ttactggtca aaatggtggt
    21901 tacgttttat tagatcctaa agaagcccct agtcgtattt tgattatgga cacaccagat
    21961 aagaatactg cacggaacgt tttgcaaatc aacaacgctg gtattggttt ctctaaaact
    22021 ggcattaatg gaacgtatga caccgcatgg acgttagatg gcggattcaa tgcctcgttt
    22081 attacagctg gtgagatagt agggattact attagaggta ctacattaat tagtgatggc
    22141 actgattata gaacaagtat agctaatggc aaaatgactt ggtactcaaa aaaagttaac
    22201 aaagatatta tggagctaga agcacgtgat tatgtaagtg ctgatgccgg cattgtatca
    22261 tacaccatga aaactggtgg tggtttcatg attagaaatc cacagggtaa cttggttttt
    22321 agtacgtggg ataatggtaa taacagaccg tttttatctt ttggtgcgcc aaatttcaga
    22381 tacagtaatg ctagttatat aaatgatggt gacggtaatt ctttaggtat tgatggtagt
    22441 gcaggtaatt catgggaatt taaagtagct ggtaggacta tgaaatttac tagtgacggt
    22501 atgctaacgt tgccaggttg tttttttggt tcatgggaag atgggaaact tgctagattt
    22561 gaacaatcaa cggtacaagt atataaagat tttactgtta gaggtactaa aaactcaacc
    22621 gtaccaacag aacattatgg acaacgacta ttgaacgctt atgaaactcc agaatattat
    22681 ttcgctgatt atggggaagc cgttacaggt gatgatggta aagttcgtgt tgatattgac
    22741 cccatgtttg ctgagacagt aaatctaagt cggtatatga cacatgtgac acctacagaa
    22801 ctagttttgt gtgctgttac tcatgaagat gttgaccatt tcatcattga aactagtaag
    22861 ccaaacgtat tggttagatg gaatttagtg gcacatcgac tagggtatga agatgttaga
    22921 ttaaaagagg atacagcata tgatagcaca gtgcttgacc aaaaacgttt ttaaaacgaa
    22981 gacaaggagg tatataaatg gctagcagtt tatataattt ggctttagat ttcagcaaag
    23041 aattaaacta caccaaagct attatggctc gtcaaggtga taaagggatc acggtgactg
    23101 ttaaaccgtt tttaaatggc ttgcagatgg atacgagcgg cggaacattt actttaaaag
    23161 gaactacgcc atctaaccgt tacgtagata gtgtcgctac tagtgtaact agtgaagaag
    23221 tcacattttc tcttgatggc acatttatga gtgaagcagg gtattataaa cactgctatg
    23281 tagaatatag aaaagacgat caaattttaa cgacgcaaga tatcattttt ttctcactag
    23341 gagtgtctga catttcgcaa ggccaagccg atgaatatgt ttcgcaatta gaagaattga
    23401 ttcgaaagta taacgaaact tttgatgctt ttctggctga aattaaaggt agaatggata
    23461 gcttaaataa acagattact gatttaactg gtcaagctaa aacactacaa gacaagttag
    23521 atgctctgaa agaagaaatt tctaaattag gtaacttaca tgtgatgtac tccaacagca
    23581 tcgacttcgg gggctatgat tatagtggga atccgaattt aatgtccaaa ctaaaatcga
    23641 gcgattttaa cgttggttac cacgggtcac taacttcgga taacgaaaag ctacatttta
    23701 cttctgatgg tacaggaagc attattatgt ttacgcgtat taatacacct cagcttgcta
    23761 gtgggaaaac ctatactctg agtgcgaaag ttcgatttga tgaaggaact acaggagcta
    23821 ttgataaatt acgtttggtg tatcgtacat caccaggaga aaagatatta ttggaagcaa
    23881 ataatacaac tattacaata gatgatgtag ggaaagaaat aacaatcaaa ggcacagcta
    23941 acgttaatta tcaaatcaca aatttagatc gtttttatat tagtgttagt ttttctaaca
    24001 gggataaaat aaatggtgga tttaaattgt acgacatcaa aatcgaagaa ggctcaacag
    24061 ccactccgta tcagccaaac ttactagatg acccttactg ggtaggtaaa acatcgttgg
    24121 gtaagaatat tgcaaataaa ggtacgacgt tcccaattaa atctagcgcg tacgaaatat
    24181 ataaaggtaa cacggaagaa gagcttataa taggtcaaac gtatactatc acgcttaaag
    24241 gaacaaaacc cgcaagtcaa acctttgtag catataatta ttggaacgtt aattttggag
    24301 atctaaaacc agttgaggga ttgacagacg tatggtctct aacattcaca ccaacgaaac
    24361 ttgaaccggg tttgcctaaa gaccttcgca tttttcagtc gcctaaagaa acggccggcg
    24421 catgccgaat tgactggctc aagatcgaaa aaggcgacac acgaaccccg aatattgagc
    24481 aatataaata ccgaggaatc ggcatgcgag actcaaacaa tccaaaagat tatgtatggg
    24541 atctagaacc tagctatgtt gagaataacc tagctacaga tatcaaggtt gctgaaatca
    24601 caggtaaagc aaacaattat accgatggga aagtatcgga gattaattcg cagttgactg
    24661 cttcaattaa tgaagtagac accacagcta aggatgctca aacaaaagcg aatgctaatg
    24721 cgactgctat agatgaatta gacaataaga tcgatgaacg cattaatgat acagctacta
    24781 ccacattaac agttacaaac gggaataccg gatcagcaaa gctttatcgt gaaggaaaaa
    24841 cagtttctat atattttgtg gctttaaacg gaaaaagcag tggtggaaat gattcaacga
    24901 tactaacaat tccagaaggc tatcggccac caattagttt tgagcaactg gttggctcga
    24961 tagaccgttc tactttgaac agtgctcaac tatctattgg cgcagacgga gccattaaat
    25021 ggagaagaaa ttcaagttat ggatcagctt attcatttgt tatcacttat tcaatttaag
    25081 ggaggaaatc taatgaaagt agtttacaaa tcaatcaagc cttacggatt cgagcaaatc
    25141 attttgaaca atcaagaaaa tatccctgaa aactgtacag agattaaacc accagttcct
    25201 aactggagac caagatttga ttttgataaa aaacagtggg ttgagttagc tactgaagaa
    25261 gagaagagtg gcacagcggt tgacgatatt gaagatgtcg atcagttgaa gcaattaaat
    25321 gctctactga caaaacaatt ggcgatatcg gtacaggaac aagaaaaaat gcaacaaatg
    25381 ttagctcaat tgacgatgga agtcgcaagt attaagaatg gagggaaaag taatgaatag
    25441 ttttccgggc tttgaaaata taaaacaatt ttatgattgg ggatgttata cggaccaaga
    25501 tttacttgac tatgtaaaca tgaactgttt aacaaaagac caatataagc agattactgg
    25561 aaatgaaatt taattaagca caaagttaaa taaaaagcgt actcaaacga gtgcgctttt
    25621 ttgcataaag gagaaataga tattggaaaa atatttaaat acattctcag taatgacagg
    25681 ggtgataggc gggacaattg ttggtttatt gggagggatg gacaatatac tacatgtttt
    25741 aatttttctt gtgggtgtgg acttcttaac tggacttgct aaggcatgga aattgaaaga
    25801 aataagtagt gagataggtt tcgaaggatt gttgaagaaa gtcttaatct tcgttgtgat
    25861 tgccgttgcg gttgaagtac agaaaatcgt tgggaattct atacctctaa gagaaatagt
    25921 tattatgttc tatgttgcaa atgaagggat tagtttttta gaaaacattt cggtattcct
    25981 tcctttgcca gataagttaa aagaggtatt ccaacaaata cgaaatgata ctgaaaataa
    26041 agaccgagga ggaaccaaat gaaaaagaaa atctttgtag gagctattat agctcttttt
    26101 ttattgccaa taaacgcctt tgcttacacg atcaacaatg aattcaattt gggcgcaaac
    26161 gaaggtagtt ctcaagtagc aaataaccaa tacatcctat tgcatgaaac agcaaacgaa
    26221 actgcgacag gacgaaatga agcgcagtac atgaaacgtt cttggtacaa tgcctataca
    26281 gcgtatattg ttggcgatgg tgggatcgtt taccaagttg gacaacctgg ttatgtacaa
    26341 tatggcgctg gttcatatgc taatgcaaat agtcctgtgc aaatcgaact gcaacatacg
    26401 cacgataaag taacgtttga aaagaactac aaggcatacg ttgaattggc tagagattca
    26461 gcaatgaaat atggtattcc attaacatta gaaacgcctt ataaccaacc aggaatcaaa
    26521 tcgcatttat gggtaacaca aaatatctgg ggcgatcata cagatcctta cggttatctt
    26581 tctgaaatgg gcgtaagtaa agaaaaatta gcatatgatt tagctcatgg atttaccgat
    26641 gaaaatccga caacttcaga tgataaacca gtcattgatc caactagagc aggtgcagca
    26701 aatcctacac tgacagatgg aacaaattac gcccacattg atcagtttgg agaaatcgaa
    26761 aatgcgaact tacacgtcgc tggatggcac atcgctaact ataaatacga gtatattttc
    26821 attatggact acaatactgg gaaagaatta gctcgagtaa gagctgatgg aatttataga
    26881 ccagatgtaa accaagctta taatacttct ggaaatgttg gttatcatgt atctttcaat
    26941 atgcgtaatt ttcctagtaa gaaagtctat gtaatgatgc gggcaacgaa tgatccagag
    27001 ggaaacacta aaggcggtgc gcaagatttc catgacaaac gttggtattt aaatattcct
    27061 aaacgataaa aatagctcct cgttgaggag cagtacataa ctatattgac aactataaaa
    27121 attattcgat aaaatagtga tgttatcgca tatcttcact atcacccat
//
LOCUS       DAYYEF010000036        26165 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000036 DAYYEF010000000
VERSION     DAYYEF010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.037"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(66..1097)
                     /gene="queA"
                     /locus_tag="ACHA1B_001760"
     CDS             complement(66..1097)
                     /gene="queA"
                     /locus_tag="ACHA1B_001760"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HFM8702522.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1290..2465
                     /locus_tag="ACHA1B_001761"
     CDS             1290..2465
                     /locus_tag="ACHA1B_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HFM8702523.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2469..3110
                     /locus_tag="ACHA1B_001762"
     CDS             2469..3110
                     /locus_tag="ACHA1B_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702524.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3107..4024
                     /locus_tag="ACHA1B_001763"
     CDS             3107..4024
                     /locus_tag="ACHA1B_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM8702525.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4021..4692
                     /locus_tag="ACHA1B_001764"
     CDS             4021..4692
                     /locus_tag="ACHA1B_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702526.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5233..5721)
                     /locus_tag="ACHA1B_001765"
     CDS             complement(5233..5721)
                     /locus_tag="ACHA1B_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HFM8702527.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5922..6188)
                     /locus_tag="ACHA1B_001766"
     CDS             complement(5922..6188)
                     /locus_tag="ACHA1B_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFM8702528.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6188..6451)
                     /locus_tag="ACHA1B_001767"
     CDS             complement(6188..6451)
                     /locus_tag="ACHA1B_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFM8702529.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6972..7112
                     /locus_tag="ACHA1B_001768"
                     /pseudo
     CDS             6972..7112
                     /locus_tag="ACHA1B_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(7254..9077)
                     /locus_tag="ACHA1B_001769"
     CDS             complement(7254..9077)
                     /locus_tag="ACHA1B_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFM8702530.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9675..12380)
                     /locus_tag="ACHA1B_001770"
     CDS             complement(9675..12380)
                     /locus_tag="ACHA1B_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HFM8702531.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12686..13633)
                     /locus_tag="ACHA1B_001771"
     CDS             complement(12686..13633)
                     /locus_tag="ACHA1B_001771"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HFM8702532.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13823..14092
                     /gene="rpsN"
                     /locus_tag="ACHA1B_001772"
     CDS             13823..14092
                     /gene="rpsN"
                     /locus_tag="ACHA1B_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HFM8702533.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14268..14630)
                     /locus_tag="ACHA1B_001773"
     CDS             complement(14268..14630)
                     /locus_tag="ACHA1B_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFM8702534.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14641..15762)
                     /gene="alr"
                     /locus_tag="ACHA1B_001774"
     CDS             complement(14641..15762)
                     /gene="alr"
                     /locus_tag="ACHA1B_001774"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008784 - alanine racemase activity
                     [Evidence IEA];
                     GO_process: GO:0006522 - alanine metabolic process
                     [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HFM8702535.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15778..16128)
                     /gene="acpS"
                     /locus_tag="ACHA1B_001775"
     CDS             complement(15778..16128)
                     /gene="acpS"
                     /locus_tag="ACHA1B_001775"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA];
                     GO_process: GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HFM8702536.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16258..17769)
                     /locus_tag="ACHA1B_001776"
     CDS             complement(16258..17769)
                     /locus_tag="ACHA1B_001776"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFM8702537.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18091..19443)
                     /gene="murF"
                     /locus_tag="ACHA1B_001777"
     CDS             complement(18091..19443)
                     /gene="murF"
                     /locus_tag="ACHA1B_001777"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0047480 -
                     UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HFM8702538.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19596..20672)
                     /locus_tag="ACHA1B_001778"
     CDS             complement(19596..20672)
                     /locus_tag="ACHA1B_001778"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HFM8702539.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20868..22613
                     /locus_tag="ACHA1B_001779"
     CDS             20868..22613
                     /locus_tag="ACHA1B_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/UbiB family protein"
                     /protein_id="HFM8702540.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22893..23330)
                     /locus_tag="ACHA1B_001780"
     CDS             complement(22893..23330)
                     /locus_tag="ACHA1B_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HFM8702541.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23314..24687)
                     /locus_tag="ACHA1B_001781"
     CDS             complement(23314..24687)
                     /locus_tag="ACHA1B_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702542.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25009..25497)
                     /locus_tag="ACHA1B_001782"
     CDS             complement(25009..25497)
                     /locus_tag="ACHA1B_001782"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8702543.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25519..26121)
                     /locus_tag="ACHA1B_001783"
     CDS             complement(25519..26121)
                     /locus_tag="ACHA1B_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VTT domain-containing protein"
                     /protein_id="HFM8702544.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5561 c         4838 g         8263 t
ORIGIN      
        1 ttttctttgt cataaaatct ttgtaaagct tttttgttat tcaaaactag cggcttttca
       61 taaccttatt tcacgaacat cgcatctcca aaactaaaga aacgatagcg ctcttcaatc
      121 gcatgctggt aagcagataa agtcaattct cttcctgcaa aggcactaac taacatgact
      181 aaagtcgatt ttggcaaatg gaaattagtt gagaaagctt ctaccacttt gaattcatag
      241 ccaggcgtaa tgaaaatatc agtccatccg ctgtctgctt tgatttctcc attaaatttc
      301 gttccaatcg tttctaatgt tcgaattgaa gttgttccga cagccacgat tttcccgcca
      361 tttttacgta cttggttcaa tcgctcagcc gcttcttccg tcaaacggta gaattcacta
      421 tgcatatggt gttcttcaat tttatctacg ctgacaggtc ggaatgtacc taaccctaca
      481 tgtagtgtca gatagactaa ttcaacaccc tttgcttcga tctcatcaag taattctttc
      541 gtaaaatgca atccagctgt tggcgctgca gcagaaccat tttctttcgc atagacagtt
      601 tgatagcgat ctgggtcttc cagacgttct ttgatatatg gaggcaatgg catttctccc
      661 aatgattcaa gaatctctag aaaaattcct tcatactcaa agtcaatgat ccgtccgccg
      721 tgttccaatt cttctttcac tactgcttgc aatctgccat caccaaaaga gattcttgtc
      781 ccaactttgg cacgtttcgc aggtttgatc aatgtctccc acgtatctcc ttgtgtattc
      841 gttagaagaa ggacttctaa atgcgcacca gtatctggtt tttctccata taaacgagca
      901 ggcagaactc gtgtattatt cataactagc gcatcaccag gctgtaactc ttcaatgatt
      961 tcatggaaat gtttatcttc catctctcca gttttccgat ccaaaacaag taaacgagaa
     1021 tgatcgcggt cttttaatgg tgtttgtgcg attaattctt ccggcaagtc aaaatcaaaa
     1081 tcttctgttg ttaacatatc gtcactcact ttctatcatg tgcttcatca ttctatcatg
     1141 tttttcgttc tgttggcaaa atcagcactt tttcacttct attttttgtt ttcctaaata
     1201 aaaaaactac cctatttgta ttttttcatt gttttaggca tactagtaat agatagttct
     1261 tcattgaaaa tagaaaaaga ggtggcacca tgattgaatt tcaaaatgtg tcaaaaattt
     1321 ataaaggtgg aaaagtcgct gtagaggacg tcaatctttc atttgaaaag ggtgagttca
     1381 tttgttttat cggtacgagc ggaagcggaa aaacgacgac gatgcggatg atcaaccgaa
     1441 tgactgatcc aacacaaggg aaaattttga ttgatggaaa atccatccaa gaaattgatc
     1501 cagtggaatt gcgacgtcag atcggctatg ttatccaaag tattggattg atgcctcaca
     1561 tgacgatccg tgaaaatatc actcttgtcc aaaaattgtt gaaagtcagt caagaagaac
     1621 ggaataaaac agctgaaaaa atgattgatc ttgtggaatt gccccgtgag atgttagatc
     1681 gctacccaca tgaattatct ggtggtcagc agcagcgtat tggagtcgtt cgtgcccttg
     1741 cagcgaatca agatatcatc ttgatggacg agccattcgg tgcgcttgat ccaatcactc
     1801 gtgattcctt gcaagacctt gtcaaagatt tacaagagcg tttgggaaaa acgatcgtat
     1861 ttgtaaccca tgacatggat gaagcgatta aactagcaag ccgtatcgcc atcatgagtg
     1921 aaggccgtgt gatccaattt gatacaccag aaaatatttt acgtcatcct gcaaacgatt
     1981 tcgtagaaga gttgattgga gaagatcgcc tactacaagc caagccaaat gcgacaagag
     2041 tcggcgaagt tatgctaaat acagcaatca cgattacacc ggaaaaatca ttacaagaag
     2101 caatcaaact gatgagggaa aaacgtgtag atacgttgtt agttaccgat aattcgaatg
     2161 tattaaaagg atttatcgat gtagaaacgt tgaataaaaa acgaggaaaa gtatccagtg
     2221 tcggcgacat tttgaataaa catgtttttt acgtaaaaga atccgcctat cttcgtgata
     2281 ccttgcaacg cattttaaaa cgcgggctga aatacgtgcc ggtcgttgat gaacagaaca
     2341 aagtcgtagg tatcctgact cgtgcatcat tagtggatat cgtctacgat gtgatttggg
     2401 gagaagatcc cgcaactact gatgttgcag agtcagctac tcctgaagaa tctaaggagg
     2461 tctgacctat gcagcagttt tttcatcagc acggttcaga aattctctca aaaggttttg
     2521 aacatcttta tatttcagga cttgctttga tcattggtat catcattgct gtaccgcttg
     2581 gtgtcttact gacacgtttt ccaaaagctg ccacgattgt gattggctta accagtgcct
     2641 tgcagacaat cccttctctt gctttattgg cattgatgat cccgctattt ggcgtaggta
     2701 aattacctgc gattatcgca ctctttattt attcattatt gccgatttta cgtaatacgt
     2761 acattgggat gaaaaatgtc gattggaatt atcgggatgt ggcaaaaggc atggggatga
     2821 ctgagttcca atccattttt tccgttgaat tgcccattgc tatgccaacg atcatggctg
     2881 gtattcgttt agctgccgtt tacgtgattg catgggctac acttgcctct tatatcggcg
     2941 ctggtggttt aggcgatttg atttttagtg gactgaataa ttaccaacca gatctcattt
     3001 tggcaggtac gatccctgta acaattttag cactattggc tgattggctt ctaggtctct
     3061 tggaacaccg gctgacaccg atcgcactta gagaggagaa tgaagaatga aacgtatact
     3121 aaaaatgacc atggttcttt tctctcttct tatacttgcg agttgttcct tccctggtct
     3181 tgccagcaat acagatgaag acaccatttc gatcacaggt ggaatcactt cagaagcaca
     3241 gatcttagca agtctagttg ccggaatggt tgaacattat acagataaaa ataccgcaat
     3301 catcaacaat ctggctacta caactatcaa ccatcaagcg atgatgaacg gagatgcttc
     3361 aatttcagcg gctcgctaca caggaacaga tttaacgact acattgaacc ttcctcctga
     3421 aaaagatccg aaaaaagcgt ttgctaccgt gaaagatgaa tttgagaaaa gatacggtca
     3481 aacgtggttc ccgtcctatg gttttgaaaa tacgtatgtc tttcttgttc gaaaagacac
     3541 cgcacaaaaa taccatctat ctaaagtcag cgatctgaaa aatgtagcgg atgaattagt
     3601 agctggtgta gatacttctt ggatcaatcg taaaggagac ggttatgacg gcttccaaga
     3661 aacttatggc ttctccttca attcgatatt acctatgcag attggacttg tttatgacgc
     3721 agtcgaagca ggaaaaatgg atattgttct tggctactct acggatggac ggatcgccag
     3781 ttatgatcta gtcatgttgg aagatgatcg tcaattcttc ccaccatatg atgctgctcc
     3841 agttgtagac aacaagatat tagctgatac gcctcattta aaagaagcct taaataagtt
     3901 aggtcatacc atcagtacgg aaaaaatgca ggaattgaac tacgaagcag ataataatct
     3961 agtggaacca tcagtagtag cacaacgttt cttacaagaa aaccactatt ttgaagggaa
     4021 gtgaagcaat tggataaaat gaatgtcttt caacaatttt tctattattt ccaggaaaat
     4081 ggctcctata tctttgcaca atttatccgt cacttcctga tttctatcta tggtgtcctc
     4141 tttgcagcag ttgtcgggat tccggttggg atcatgattt ctaggagacg taaattagca
     4201 aactgggtga ttcgtttggc gaatatcatc cagacgatcc cttctctagc catgatctcc
     4261 attttaatca ttggattagg cctgggagtc aatgtcgtga ttgttactgt atttttgtat
     4321 tccctcttac cgatcatcaa gaatacgtat accgggatga tccaagtaga caaaaacatc
     4381 cttgatgtcg gcaaaggcat ggggatgact gctagacaac gactattcat ggtagagtta
     4441 ccactctctg tttctgttat catggcaggc ataagaaacg cgttagttgt tgccatcggg
     4501 ataaccgcga tcggtgcatt cgtcggtgct ggtggtcttg gagatatcat tatccgagga
     4561 accaatgcaa cagagggcac atcgattatt ttagcaggtg cattgccaac tgcattaatg
     4621 gcgatcatca cggactggct tttaggtatt ttggaaagac ggctagatcc agccagccgt
     4681 acatcacgct gatgttattg taaaaaacaa aagcttctgc gaccatttgt tggtcgcaaa
     4741 ggctttttta gttctgtcat ttttaaggca ataatccact ctgattcttc cctccttatg
     4801 ggcaaagagt tgcttttctt agctatttat ccattccgta tactccaact tcatactgcc
     4861 aacgggttca tatctgcatc caccgactaa gtttttttct tatccgctaa ggcattttgc
     4921 caatccattt tcccatcact cgtcatggaa ttcataccac atgatctcta aatactcgtc
     4981 tgcttgttct ttgaattggg catcaattct tacatccttt ggcgtggctt tcatttaagc
     5041 cttttccatc agtcctcgat tgttcgatgc cttcagctgc atcatcaaaa ctggtgactg
     5101 ccgtatcggt aacttcgatc atcttttata caatcgggaa cttgccatcc tcatccttgg
     5161 ctaaaaacat atctagccat tccagcttct cgccatggga ggtttgcggt tcctaaaacc
     5221 ggtacacgat tcttatggac tgcatccgtc gcaactagac ttggcgatac gatgatcctt
     5281 caccagaaga gcacccccgt aaaccaattg atcgatatat tgccaataag aaaagacatt
     5341 ggcgtaaaag atatcgatcc ctcgtgatgc attgccgttg atactgctat tcatggccga
     5401 aagcgccacg actttaactt cttccgtttg agtgacattc atgttcggca atgtcgcttt
     5461 ggatacccgc tctgctaaag gaacgacact ggtattgtat ttcgtatctg tatcttttcc
     5521 aaaagaccat gccaacgaat cctctgggaa ccaataagac gactccggtt gattgtccat
     5581 tgcttttttc aacatacttt tggctgtttc tcgataaacg acatttccaa ttgtcttcgc
     5641 ctcactttgg cgataatcga tggtcgttgc cactgccaac actaacaacg atgctccaat
     5701 tttactgatt ttccttgtca cacttcttcc tccttgtttt acataaaccc gtcaacattc
     5761 cattcctaaa ctcaaacaat gacccttcaa aggtggagat ataggaacaa attaaagaaa
     5821 tcatgcaata aatccaagaa ggttggtttt agaacaaaaa aagagtctcc tttttgggga
     5881 gactctttgt taactatcta aaaaggttgg ctcttctcac ttcactcata atgtgtccag
     5941 gcagaataaa tttctacaac tttattttcc tcatcaactt tgtaaaccac tcgatgctgt
     6001 ctattcagcc tgcgtgagta tctgccttca tgtgtaggtc tcagcttttc aaaagactgc
     6061 gtgggcatat atggatcttc cttcaatgtc tgaatcactt cttcaaattg tttctttaaa
     6121 ttcgtttgct tgatttttct taaatccact ttcgcagagt ttttgattgc gactgtatag
     6181 ttactcatca aagagcttcc caatcaatat catcgatatt cgtaaagcta ctgtcgtctt
     6241 tttcgcggtc tcgtacttta tctaaagtac ctgtttgctc aagaaaaagg gtttcttgaa
     6301 tcgctctcca gtcttccagc ccaatcaata cagcattgtt tccactacga tcactaataa
     6361 tctcgatttc agtatgattt tcatttacct ctttcaataa ctgataaaaa tttttacgag
     6421 cagtgctagg attcatcgtt gtattagcca ttgtctctcc tcctttttct gatataatta
     6481 tagcgtactt gattaagtac gtcaaaaaaa tacaataaag cacttaaatt cagcaaactt
     6541 ttcctctttt ttacatagag aaaaagaccc ctttttaggg aggatctttg tccacgctca
     6601 cttcttactc ctttacgact agcggtagcc aaacgtaaag taattggtaa caacgtatca
     6661 tctttagcaa aggtcgaatc caaagcctgt gagtctatgc aacaacacca atacacgaag
     6721 gttcctcgtt gcagtgtgac ttgattgata tcttgaataa cctgaggata cgcacgaaag
     6781 atttgtaacg gttattcaaa actgattttg gccgtcaagt cttctactgc ctcaaaaatg
     6841 attgcctctt tcgtctcctg tcattcatgt tcactatcga tttgatactt gcttagaccg
     6901 ttgggtttgt gaatcaccaa ttaaaaatgg cactgagtta tggtaacaaa aaatggtcac
     6961 ttgacgaggc tgagattcct acttatgaag acacatggca cttaagagtc gaggtaaagg
     7021 aagaagctga aaatatagga ggctgtacat tatttggcaa aggattcgga aattatgatc
     7081 aagacatcaa aatcaaaatg ttttacagct aaataggaag aataataaca tttcatacgc
     7141 tgttcccatc tttaatggct tatagagggc acctttagct gagaataaga caaaacagac
     7201 cctctagctt caattaagag ctagagggtc tgtttttgat tttaaaactt ggtttatttc
     7261 ttcaaatggt agctataggt gctgacaacg atattttcac gccaagacaa tcgcaatctt
     7321 aaccgcaaac ttgtttggtt atggagaata ttctgccagc gtctgtttgg tacaaattga
     7381 ggaatcaaca cagtagttgt atagttttgt ttcgctgcat ttttacttac gatatctaca
     7441 taacggataa ttggattttc aatcgagcga taagaagagt ggacgattga aaaacggaca
     7501 tctgggaaat gctttttaaa ttctgcttcg atttcttttt ctttttcgac atcttcgtct
     7561 agcgaaacat gcatcgcaac gacataatca ccgatcgaac gtgcgtaatt caacgcaccg
     7621 atatttaccc gtgtcacatt cccgactaat acaagaacgg tattcccgtc ataatcatgt
     7681 agttttgcat cattttctaa acgaagctgt tctgctactt ttttataatg atcatggatc
     7741 ttataaaaaa tgaacataac gattggcata atgatgaaga aaggccaaat gtcccctaac
     7801 cgatagacaa acaaaatcgc aatgattgca tatgagatga acgcacccgt aatattggca
     7861 atcgatttgc ttaaccatct ttttccttct tttttccatt tgacgaccat ccctgtttga
     7921 gataaagcaa atggaatgaa cacgccgata gagtataacg gaatcaagcg ttctgttgag
     7981 ccatggaaaa taaacagcaa tacgatcgaa cctagcgcta gtgtgataat cccattggaa
     8041 tagcctagtc gatccccacg atcttgatac atgtgaggca tgaatttatc ttttgccaga
     8101 ttgtatgcaa gaactggaaa agcagaaaaa ccggtgttag cagcaactgc taaaatcagc
     8161 gctgtagcaa attgaaggac gtaatacaaa ataccatgtc caaagacagc tttaccaatt
     8221 tgagacaaaa cagtgacttc tttttcagga acgatcccat accaatagtt gataaatgtg
     8281 atccccacga agaagaaacc taagatcaat gccatcatcg tcaatgtagc agcggcattt
     8341 tttgctcttg gcttcttaaa gaatggtaca gcattactaa tcgcctccac cccagttaaa
     8401 gaggaagaac cagaagaaaa tgctcgtaaa atcaaagcga tagaaacacc cggcacagcc
     8461 gctcctggaa gtgcagtagc ttgcaatggc acagcacctg tcacgatatt atataaacca
     8521 acaacgatca gtaacgagat cacaaggata aatgtgtaca ccggaaataa taggaacgat
     8581 gcagattccc tcagcccacg aagattcagc atcatcagta gcaaaacgat tgtcacagaa
     8641 atagcgactt gatgaccgta gagtgctggc accgctgatg tgatcgcttc agcacctgct
     8701 gagacagata ctgctactgt caacatgtag tcgatcaata aagagccacc ggaaatcaag
     8761 ccagcattct ttccaagatt ctcactgctg acgacatatg ctcccccgcc atgaggataa
     8821 gcatggatga tttgacgata tgatagcgtt aatgaaatca ataaaataat aacaaaagcg
     8881 gcaatgggta gcgaatacca gatggctgca gcagacaaag cgactaaaac gacaacgatt
     8941 tgttccgtac catatgcaat agatgataac gcatcagacg acaataatgc caaagcagca
     9001 aatcgggtta atttgtgctc atcattttca gcagatttta aaggcttacc tactaacaac
     9061 ctttttaagt aatccaattt ctaaactcct ttacacacaa ttttacttca agttttatag
     9121 tcgaaaattt atagtaaaca agatgttata gtacgctcac tgaccttaaa agtcaataaa
     9181 ctttaagaaa ataattggaa aaaaacagaa aaatatcaag cgctttttca aacgctttaa
     9241 tacagcaaaa atctaacatt tttttatggg ctttttcttt gaattctata ataaaaggat
     9301 agaacttgac ttagaaaatc aagttctatc ctttttgata tcttaacttt tggaagagag
     9361 atgtaaggct gctttctacc catcattctt actactcgaa gcatagcgca gttgtcacaa
     9421 cctcttgata aacggtgttt aaaagcttgc atctgcggta ataagcccaa ccaaattaaa
     9481 aacataagaa gctgttttta tttggtcgtt cttattactt gatgcagagc agctttttta
     9541 caacctcttg gtacacggtg ttcaatcagc tgaccctcgg tattagctca aaaaaacggc
     9601 aaaatatgag gaactatttt tccatttttt tctctaatac tcaggtcaaa acactgattt
     9661 cacaacctct ttttttaatg aaaaatatgg ctctcatgcg ccgcttcttt gaatttcgtc
     9721 attttttctt cgatgaacgg atagattgcc gttcctacga ttccaaagac aacaaacaaa
     9781 ccgatcatga tccagattgc tttcgtagca tttggccaat aaattcctcc tgcagattcc
     9841 cgtaacaagt ttaccgcatg agtaaatggc aagaacggat tgatcatttg gaagaatttc
     9901 cctgagactt ggatcggata gttcccgcct ccgccagaga tcgacagtac taagatgata
     9961 atagcgatcc ctttaccgac attatcgaat aatgcagcca agacatagac gatcatcatg
    10021 aacgctaagg cgatcaagac agcaaatgac acgctgtaga ccggattttg gacatctact
    10081 cctagtaaga aaatattccc taatgtaacg atcaagcttt gcgcaatcgc cattgtcaaa
    10141 aatgtcagca tacgagcaac gaattgttct cgtttcgtaa aattgtttcg gtctttcttt
    10201 cctaaatagt attctgtcgt agcaacactt gaaagaagaa cagcgccgac ccacagacat
    10261 agtgcagtat aaaacggggt gctagctgaa ccgttatttg cgattggata aagcgcattg
    10321 gtttgtagct caacaggttg tgtaaagaag tcactttctt ttgttgcgtc tagtttcaat
    10381 aatttgatga cttcgcctag atcgacttct tgttcgcctt ttcggatcgc gtctgctgct
    10441 ttttggatac cagctttgat atttggccag tcattgttga tcaagtccgc agcagcgttc
    10501 acagctgttt cgacttctgg cattttttca tttactgttg tcaatgtacc ggtgatttca
    10561 ttttttagtg ctggccaatc attttggata aaatcagcgg ccaatcctaa tttttgctga
    10621 atgatcggta attcattgtt gtataggtct gccccttcat tgatgccatt gacgatggta
    10681 tccatatttc cattcagcat tgtattggca tcatggattt cttgtccaat tgcaggcatt
    10741 tctttttgat atttttctaa aattgccact gcattcgtta cagttgcttt cgttgagctg
    10801 agaagcgaat caaagtcgat ctggtccgct ttgctcagtg cgccttgtgc agtcccaatc
    10861 gtatcgatga cttggtctag tagagaagtg acagtggaac tgatttgacc tgtattgata
    10921 ccagcaatga tgccattgat attattaaca acggcatcaa tttgatctag caattcatca
    10981 atagccttcg tgtcttcatt ttgaacagct gtgttcaaag cagataggcg gttttgcaga
    11041 ttgcttagca agggttttaa ttgatttagc tgatcaataa ttggctgtaa tttcgtattt
    11101 ccagcacttg tttgcaattt agtcaggaac tcgaccagtt tatcgattgc attttgttgt
    11161 tgagatattc cgtcaataaa gccgttcaat acattgctga tgtttttctt ttcatcatca
    11221 gtcagcttac catcttcaat agctgttctt acagtatcta ttaacgaacc tgtcgttgtt
    11281 gccacttgtc caattgactt caatgtaaca tctacactgt ttgtgatgct tggtatcgca
    11341 tctttcagct gagaggcacc tgattttgtt tggtttgcta gatcacttgc ctgattttct
    11401 aaatttttca catctggcaa gatatcttgt acttgttgga tgatcgtcaa gccttgtttt
    11461 gcttcatcga ttccttggtt cattgtctct tggatcgaag caaaatcgcc gtcgatctct
    11521 gctagttgct taccggcatt ttggatctct gggatttttt cttgcaaatc aaggatgatt
    11581 tttgcttgat ctttcaactc aggcattttg tcattcaatg caacgacttt ttcacccatc
    11641 tcatctactt tagggatgta atccacgaat tcatttgctt tattcagttt ttccttgatt
    11701 tcaggtagtt gactttgtaa ttcgaggact tgttttgtgt agccgtcgat cgtgtccaaa
    11761 ttttcatctg ttgataaaat catatcttta actttattga tacttactag gttcgtatcg
    11821 atgtcgtaac ctatctcatt gaatactttc aataaagtcg aactggctgt tttgataaat
    11881 tcatttgtga tttgcgattg gatcgaactt gctcctttat cggtgatttt cggtgcaatc
    11941 gcattgattt tttcatttac cgtatattcg atttttggtt tcttgatatc accactagta
    12001 aaactcagca gatcttctga gaaatccttt ggcaagtaaa tacctgcgta atactttccg
    12061 gaacggactc cgtcttctaa ttgttctttt gaatcaacga attgccatcc taattgttta
    12121 tttttatgaa gcgattcgat gacttgctcc ccaatggcca cttctttacc ttgaaactct
    12181 gctggcttgt ctgcactgta aacagcaatt ggcagctctc cagtatttcc atatggatcc
    12241 cataatgctt tgatgttaaa ccacgcatat agcgaaggga tgatcatgat cgcgatgatc
    12301 agaagtgttg caatcgggtt tttgaaaatc cgtttccagt caagcaaata taatcgaagc
    12361 gtatttttga ttgactgcat agttctcccc cttcttcttt tttcagctga attactttac
    12421 catgtatttc atactttttt caatcggctt ttttcaaaaa agtcgaattt ttggacatat
    12481 cacggcaatt gtctcattgt aatctcttac atattgagaa ataattaagg attacagcct
    12541 ttactttatc atgaaataaa agggaaagat aattttatgc caaagttttt atctattata
    12601 cgtatacgca aaaaagctaa aacatttttt gtctttgccc ctacaaaaat gtttcagctt
    12661 ttttcgtttt ttattcctgt atttcttatt tttcgaatga caggatgatt ttcccagcag
    12721 gaggatgtcc ttcaactagc tgatgtgctt ggatgacatg cttaagtgaa gcagacagat
    12781 tcattgaaat aaaaacatga aaggctcctt tttggtaggc tttgattatg ccagcaaagg
    12841 cttctgcatc tagatattcc tttcttggaa caaacgattc ataaaagcct tccttttttt
    12901 gccgcaaatc tagatctggg aggtcattta atgcaacata cctgccgcct ggtttcatga
    12961 tctggatgcc ggtttctcct ttgatacttc ctttcgtcgc atcgattaca aggtctgcct
    13021 gatcagcaaa ttgcagacct ggatttgttt tatcataagc agcaaatgct gaagctccta
    13081 atttttttac cttttcctca tttttactgg atgcactggt taagattcgg attccctttt
    13141 catggagaag ctggatcaga cttgacccga ccgcacctga tgctcctagt atcattacag
    13201 tatctgtcgg ctggatttcc gtcaaatggt tgattagatt ataagccgta attcctggcg
    13261 tgaccattcc ggctgcttct tcccaactca ttttatctgg aatttttgct acttttgctg
    13321 atggcaacac gacttcttct ccgtaagtcc cgccgactgc atggacagct actcgatcac
    13381 ctacatgaac agttgtgaca tctgaaccaa tctctgtcac aataccagcg ccatcattac
    13441 ctggtacata agggaatttc aatgttcgta tctctttcat ttctcctaaa cgcaaggcaa
    13501 catcataagg attcacactg aatgctttta tttctacacg aacatgtcca gaaccgactt
    13561 ctctgggatg agcatcgatt tcttcaaaaa catcttgtgc ttctccgtaa ccgttaattg
    13621 caaatcttcg catggtcacc atctcccttt ttctttaagt ttacgtttat gcctttattt
    13681 tgacaaaaaa aatgtctttt cgttttggcg catgattcaa aacaaaatag ttgtcttttt
    13741 tcgcgtaacg tgttaaatta tttatctaaa agcgtaaaga ttacgattta cgctaataaa
    13801 aaataattgg aggaatttgt tgatggctaa aaaatcaaag attgccaaag caaaaaaaca
    13861 gcaagaaacg attgaacgct atgctgcttt acgccaggaa ttaaaagcgc aaaaagatta
    13921 cgaaggcttg cgtaaacttc ctttagatgc tcgtccagaa cgattgaaaa atcgtgattt
    13981 aatcgatgga cgccctcgcg gatacatgcg taaattcggg atgtcccgta taaaattccg
    14041 tgaattagca cataaaggtt tgattccagg agtaaaaaaa gccagctggt aatccaagtc
    14101 tggctgtaat gtaaaggagg agggcgcatg gaccactcct tggatcatca aaaaagatac
    14161 gttcgcttct tctagcagaa atgctggtac tagaagcaga cgtatctttt tttacgcaca
    14221 gctggtcctt ttttatatgt aaaggctgca tggttacttc gctatattta tttagtaaca
    14281 ggagtcagtg cttcgatacc cacactaatt ttcaatgctc ggtcaacttc tgccataatg
    14341 ggtcgatcca aatggcagac cttttctttc aatcttgatt tatcgatcgt tctgatctgc
    14401 tccaacagga taacggagtc tctttctatt cctgttccag tagctttgat cccaatgtga
    14461 gtcggaagct taggtttagc catttttgcc gttatggccg caacaatgat cgtcgggcta
    14521 aaatggttac ctagattatt ttgaataacc aaaactgggc gtgttccgcc ttgctccgat
    14581 cccacgactg gagaaagatc agcaaaataa atatctcctc tttttaccat aggatcctcc
    14641 ttattcttga tattctcttg gtatccgctg tcctaatccg caagccactt catagtggat
    14701 cgtacctaat tgatctgcta tatcctgcat agtgatttct ttgtctgcat ttttgccgat
    14761 aagcgtcact tttgttccga caggaaattc ttgaggcaat cggatcatca gttgatccat
    14821 acatacacgc ccaatcgttt cacagtagtt cccttctacc aatagagaaa aaccctgcat
    14881 ctttcgtggc cagccatctg cataaccgat cggtatcgtt ccgatccact ctgcttcagg
    14941 agtgatatat gtttctccat agccgattcc ttcacctgct gggagttttt tgacttgaat
    15001 caattcagaa accagctcaa gtgctggctg caatggataa acttccggta gtgcgtgccc
    15061 agagggatta agtccgtaca ttgctactcc ataacgaatc atattgccga ttgtttcatc
    15121 atgccataaa gccgttgcac tattgctgac atgtacatat cgaggaagtt cgggaagttt
    15181 tttcagcact tctataaagc gttctttttg cagattccaa tatgtatcat ctgcctgatc
    15241 tgctgtagaa aaatgggtaa ataaaccttc ccattctaat acacgacttt ctttgatgaa
    15301 tgcagctgcc tcttttactt cttcaggtgt acaaaatccg atacgaccca tcccagtgtc
    15361 tgcttttaga tgaatcgaaa gaggcgtctc tagcttactt ttctctaaaa cagcagctgc
    15421 tgcttgcaac cattcccgtg tacctgcagt tactgataaa tcatgagcaa cagctacagt
    15481 cagtgcgtcg taaggaacca tattcaagat aaggatgggc tgagtaaatc cagcttctct
    15541 caactcgact ccttcatcta aatttgaaac acaaaagccc gaagctccac ctgcaactgc
    15601 tgcctcagct gtttcaatag ctccatgacc gtatccgttc gcttttacta ctgcaaacaa
    15661 ttcttttcct tgcggaagtc ttgcaacttc atttgctaca ttttcagtta tagctttttt
    15721 atgtatcact gctttcgttg ggcggtgcca agcgacaacc atcgtttttc cttctttcta
    15781 gtcttccaaa ataatttgtg caaaagctgt ttcatttgta tgagtaatac tgacccatac
    15841 attgccttca tgaggtgaac gcgtcacaac aggctgacca ttttcatttt ttaaaatctc
    15901 gacatcttga aaggtaactt ttccgatccc agttccccaa gctttagaga aagcctcttt
    15961 gcaagcgtaa cgcccgccta aaaattctac ttggcgatga aaaggcaagg actggaatag
    16021 tttcatttca tcagaggtca agattcgtgc aatgaatttt ggtttttctt cgatcagccg
    16081 agtgatccta ggaagttcga ctgcatcgat cccaattcct tttatcatat gcttttctct
    16141 tttcaataaa tttagaacac tctcattcta ccaaattata accattttgc cacaaataag
    16201 tccacaaata acaaaaatga aagtttctct taaaaaagag aaactttcat tttatgttta
    16261 atcgttattt gaacggatta caaatccgcg ttttttatca ttgtgacgtt taccgccatc
    16321 tttttggctg ttattatttt tgctataacc gccttttgat ttgtttccac gataattacc
    16381 gccgtcacga cgattacggt tgtttccgcc accacgtttg ccatttttat tgtatccttt
    16441 tttctgcatt ggcaatgggc gttctggtgt gatcttcact ggcactgcat cagctggatc
    16501 ttttgctgtc gtttttagca aaagtgcaac taaatcttgt gcagaatatt cttctaataa
    16561 tttatctgct gtttgcaggt atttatctag accattttct gcaagttttg tttcgatttg
    16621 ttcaactgca gcacctaatt gacctttgaa tgcttctttt tcggttggtg gacgtaaagt
    16681 cgtcatccgt tttttcgtca agttttcaat cacatgcaag tagtccattt catttggtgt
    16741 aacgaaagtc acagacatac cgccttttcc ggcacggcct gtacgtccga tacggtgaac
    16801 gtagctttct ggatcttgag ggatatcata gttgtacaca tgagtgacac ctgaaatatc
    16861 taatccacgt gcagcaacgt ctgtcgctac aaggatatct aaatgaccgc tcttaaatga
    16921 acgcaatacg ctcattcgtt tttgttgaga caaatcgcca tggattcctt ctgcacggta
    16981 accgcgtgct tctaatccgc gtgccaattc gtctacacgg cgttttgtac gtccgaagac
    17041 gattgttaat tcaggtgttt gaacatcaaa caagcgagtc atgatatcga atttttcgta
    17101 ttcttttgcg cggacatagt attgatcgat caagtcagct gtcatttctt tcgctttgat
    17161 cttcacatga tgtggatttt tcatgaattt aacgccaata ttcttgatag ctggcggcat
    17221 cgttgctgag aaaagtaatg tttgtctttg atcaggaact tgtgaaatga ttttttcgat
    17281 atcttccaag aagcccatat tcaacatttc atctgcttca tccaaaacta atgtttgaac
    17341 ggttccaagt ttcaatgtgt ggcggttaat gtggtcaagc atacgtcctg gtgtacccac
    17401 aacgatatgt ggacgatctt tcaagccacg gatctgacgg ccaatatctg ctccgccgta
    17461 aacggcttgt acacgtactt ttttgtcgcg ccctaaacga tataattctt cttgtgtttg
    17521 gatagctaat tcacgtgttg gtgcgataac taaaccttgt aattcgtgac gatctggatc
    17581 gattttttct aacattggta atccaaatgc agctgttttc cctgtacctg tctgtgcttg
    17641 tccaataacg tcttttccag ctaatgctag tggaatcgtt tctgcttgga taggcgttgc
    17701 ttcttcaaaa ccagcgcgtt cgactgattt caacaattct ggtgataatt ctagttcttt
    17761 aaatttcaaa tgaatcctcc tatatggttg ttaactgagg atgtagcttt tttgctaccc
    17821 cgtcgatttg ttcggtcaaa gtgtattgtt tctttttgac agtggccacg cacgttttta
    17881 tccattctta gcccctgtgg caccaccgaa aaatcacttt gcgaagttta ggcattagaa
    17941 aagccaaacg ggtcgcgttc agctttatca ttattatgac atctggcttc aacaagttgt
    18001 ttctatggca aaaccagtcc aatttctctt catctttcgg caataggtta ttctaacata
    18061 gtttttcgtt ttctgcaagt ttacagattt ttatttcatt tgctgaagtt gttctaccac
    18121 ttcaaataag cccatgctgt tgctgccttt tagcataata ctatctgttg cttcaagatt
    18181 ttgtttgata gcatcaatca atttattctt ttctttttcc aaatagaaca caggtagttg
    18241 ggggtatttt tggttcaatt cttcttttag tgcatgcatt tgttccccat aaaggaaaat
    18301 catggcgaat ttctcaggat cgatatgttc actcatttgc gcatgcatat ttaaagactc
    18361 tttccctaat tccagcatat ctgctaacac agcgattctg cgtccttttg ttggcagatt
    18421 tttaaaagta tctaatacca gtcccatggc tgttggattt gcattgtaga catcgctcaa
    18481 aatagctgca ccatttcctg ccgttagcca ttcggttctg ttttgagtga tagaaacatg
    18541 ggcgagccct tggcgtatct caggtatgga cagtccaaag aagcgcccga tcgtatacgc
    18601 aatcaaagca ttcgttacat tataacttcc aggcagcggg atcgtaaatg tttctccttc
    18661 tactacaaaa tcggtttgtg cttttccttt tgctgtcact tccgcatgaa catcgccatt
    18721 tccaataccg aatgttgtga ctgtttgtac taatgttgcc gttaaaggtg tcagcaacgg
    18781 ttcatctgcg ggcacaacga gtaatccgtc tgatacaagt ccgtcagtga tttccatttt
    18841 ggctttagcg attccttctc gcgacccaag attttctatg tgtgcttcac cgatcattgt
    18901 gattgctgca gcttttggtt gagccataag tgaaagttcc gtgatttcat tggcgtgatc
    18961 catgcccatt tccaaaacga tcttttctgt atcttggggc atgtgcaaaa tcgtgtaagg
    19021 aagaccaata ttattgttgt aatttccttg cgtcttatat gttttgtatt tttcagacaa
    19081 gacagacgcg gttagatctt tcgtggtggt tttaccattg cttcctgtaa ttgcaacgac
    19141 ttctgcgcct actttttcca agtaataggt tgccaattgc tgcatggctt tcaaaggatc
    19201 tgctacagga ataactggaa aattttttgg agcttgttca acaggcaagc tccaaaatga
    19261 agcagatgct ccgtttgtga tcgcttgctg gataaattca tgtccatctc gcgtaccagc
    19321 aagaggaacg aataaacttc cttcggttat cttccggctg tcaaattcga cattggtaat
    19381 ctttgtcagt gcagagcatt cgctgcccac ggcttgtgca atttcttgta ttgttagatt
    19441 cattgagatc tctcctaaaa aaggttgtga aaaaagcgtt tggcctaaac ggcgggttcg
    19501 catgactctc acttccaagt aaatttctct attcgtattt agaagctaga atgaacgcgg
    19561 ttacgcaatc actccagcct cttctttatt tctctttatt catttttttc aaaaaaagat
    19621 tgacgctgat ggtatcgatt cattcctaac tggatcagtt cttcaatcaa atcaccgtat
    19681 ttcaagccca tattttccca taagagtggg tacatactga actccgtaaa tcctggcata
    19741 gagtttaatt cattcaggaa taattcattt ttatttgtca aaaagaaatc gcaccggctc
    19801 aatccgcttc cacctaacat cgtgtaagct aacttcgcgt actcttgcgc tttttgataa
    19861 acttcttctg gcacttcggc tggaatctgc atttcgattt tattattgat atattttgct
    19921 tcataatcat agaatgctac gtcttttacg acttcaccag gcaaagtcgt ccgaacgtct
    19981 tcatttccta atacagcaac ttcgatttcg cgcgcttcaa ttccttgttc aacgattgct
    20041 cgagaatcat actgataggc tgttgctaaa gcattttgca gctcttctcg gttttctgct
    20101 tttgtaatgc cgacactaga acccatattc gccggtttga caaacatcgg ataaagcaaa
    20161 gaaccttcac attgatcaaa tactttttta ggattttctt tccattgatt cttaagtact
    20221 ggtacataag gaacttgcgg cacaccagca gcttgtaaaa tatacttggt catgatttta
    20281 tccatggcac atgcactggt caatacgcct gcgccgacat aaggcatatt caatgtctct
    20341 aagaagcctt ggatcgttcc atcttccccg tttggcccat gtaaaactgg aaaaacgatg
    20401 gctccttctt ctttgatttc gcccggattg atcacttttc ctgtaaagcc ttcctctgtc
    20461 tgtccacttg ggtcccatga aagatgcaag acatctttgc tggcaggttt ttctgttagt
    20521 aatggacctt tgacccattg tccttctttt gtaataaata cgagttgaac ttggtaataa
    20581 ttataataaa tggcatttaa aactgaaaat gcggaaagaa tggacacttc atgctctgcg
    20641 ctgcgtccgc catatagtaa agtaatcttc aaaagattgt cctcctgtat tctaaatcgt
    20701 tcagtgattt actctcatat tttagcacaa aacaaaaata aacgaataac ttatttataa
    20761 aaaaacgagc cagcttctaa aagaacgagc gtcatttatt ttttgtcagc tagattattt
    20821 gtcccgtttt ttataaaaag ttatgataaa gaaaaggagg gatgatgatg gcgcaaacaa
    20881 atccacgcag ccgcttggca gaaatcattc gagtgttcat caattacaat gtagtgccaa
    20941 actttgtaca gcaaaaaaat cccgaacagg taaaaaaagc ctttgaagaa ctaggcccca
    21001 ccttcatcaa gataggacag atgctttctg ttcgagaaga tttgctttct tctgccttca
    21061 ctcaaacatt caaaacatta caagatagtg tacctagcga cacattttca acggtcaaaa
    21121 agacgatcga aacagaactt tctctttcat tatcagatat attcgatgat ttttcaaaat
    21181 cgccttttgc ctctgcttct atggggcagg ctcatcgtgc caagctgaag aacggtgacg
    21241 cggtagtcgt taagatccaa caccctaaca tcgccgaaga gatccgactt gatcttcaac
    21301 tatttgaacg agcgatccct ttgatcaaat acattcctga aactagcgta gttgatctaa
    21361 aaggggtact ccaagaagta aaacgttcct tgatcaatga aatggacttc ttaaaagaaa
    21421 gtcaaaatgg cgaacaattc tatcaaaaga acaatggctg gaaagagatc cgcagcccca
    21481 agatttatga cgctttttgt tcgaaaaaag tgatcgtgat ggaagaaatg tctggtaaaa
    21541 acttgaatca tttaatgaac gccgaaaaca aaactgaaac ttttatcact ggaattcaaa
    21601 acaagcagct gaaacaagaa gttgcaaagc ttttagttga gaactttatg aaacaggtgt
    21661 ttgatgatgg ttttttccat gctgatcctc atccagggaa tctgctattc catgtactaa
    21721 caaaagaaga acagacacaa gctagccgaa aaactgaaac agtccatgaa aaagagttcg
    21781 gttcctttgc ttttcgagcc tccacttctg cagaagaccc tgttgcgcca tataccatca
    21841 actacatcga ttttggtatg atggggcatc tttctgcagg acttaggcaa aaactcacac
    21901 aagccgtttt agcgctgtat acgaaagatg cttatcgaat cgaaaaagcg gtccttcgac
    21961 tttgtcagca agaaggctcg tttgatgaaa gtcggttcca ccaagaactg acaagttttc
    22021 ttgaacagta ttatgattct cctattgatg aaatcaactt gcaagaagta ttcacacatg
    22081 tcgtgacgat ttgtcatcaa aataatctgc agttcgatcg tgatatcacg cttttgctga
    22141 aagcatttgg gacattagaa ggggtgatcc gcgtcctcga tcctgaagtt tccctcatgg
    22201 aagtcgcttc gccttttgct caacattatt ttctcactca tctggatgta gaagatacat
    22261 tgaaacaaag cggattagac ttattggaag ggatgaaggc tgcgcctaag atccctcaac
    22321 agctccacca tctattagaa atgtggactt cgggacaagg aaaagtcaat ttggaattga
    22381 aaaagcaaga caaattattg agcaggatcg aaagtatgat caatcggctt gttttcggta
    22441 tgattttagc tgcattgatc gtagggtcct ccctgcttgt ccaagcagca cctgtagaaa
    22501 acgcagaggt cgtttcctta ttagggatat ttacgtatgc tattgccgca ttcgtcatta
    22561 tttttttggc aatcgatgca ttgatccaaa tgtataagaa gaggaaaaag tagaaaaagg
    22621 ttgtgacaga aagaatcagc ttcaagaaat aagaaggggt tttacataaa ttgtttctca
    22681 aatttttgtg aaaattcggc ttatttttcg aagaggctac ttctgaaaca ccgagaataa
    22741 aaaatgtgaa aaagctgttc tgcacccagt aataagaaca atcaaaaagg gaacatggaa
    22801 cacatttatc ctgtttccct gttccctttt tgatgtattc gagcataaat aaaatacctt
    22861 cgttacctac tatcttctgt acttggtaaa ccttagtcaa ttgccttttt taacgcttga
    22921 cgaaaagaca tatgatcttt ctccgtaaag ggttttggac cctttgtcct tatgccagct
    22981 tttcttaact ttccactatg ataacgttgt tctagaagcg tgccgatatt cgcttcgtca
    23041 aattcttttc cagagtgatg gaacactcgc acacccttcg gcaatacaag tgaagctaaa
    23101 ccataatctt gcgtgatcaa aaagtcattc ttcttaacca taccgacgat tttataatcc
    23161 gcactatcag ctccgcggtc tacgtagacg atttggacat gattagcgta ttctttggtc
    23221 gtataatggt ccacactggt cacgataacc acgtcaagac cataggattc tcctaatttt
    23281 atgacatctt cttttactgg agaaccatct ccatcaatga atagcctcat tctttttcgc
    23341 cttcttccat aaatgataaa cagttactaa tccgctcagt aaaagaccaa cattgatcca
    23401 ttttgccaag ataagcagtt gtacactttc tatcggcact gattcatggt tcagcgtgat
    23461 caataataga tggattggct ctcccatttc ttttgctaaa acaaacaaaa gcgtcatcaa
    23521 taaaaactgg tggatcacac tccctttatt ttgagtagta tacttgacaa cgatccggcg
    23581 atccattgga atagctgtat cagtttgata atattcctta tttagccagc tgcctgttac
    23641 tacgtgccag aaactaagca gaaagacacc tatcgcaaaa ccatttggaa tcaagaggac
    23701 caataaagaa gaactcagtc caagcaattg catagccaat ggagaccatg ttaaacgttt
    23761 caaaatccat ggtccgacta tttttgctgc aatcaagcct gctgcataag gcaaatacat
    23821 aaaaatcgaa agtttttcta atccgtacag tatgccaaca taaaaactgc taaataaaaa
    23881 aaggaaattc cctagcattc catttagaaa agtaaacaga tttagccagc ttggcaactt
    23941 ccattccttc ttctggtgtc ctaaaacaaa cacgaacaag atgaacagca gcaagaaacc
    24001 ataaatagca agatcaaaaa gcctttcatc gaataacaat cgggcatttc tcaaaagaaa
    24061 caataagcca aagaatatca aaaataaaac aagctctcgc gtagctacca gatttctttt
    24121 gatgtctttg aaatccagtt cgtaacgcgg ataatgacta accgtatggt aggccatgac
    24181 gtaaaaaagt gtataaatag taaagcttgc tgcaatctga gtcggtgcag gcaactcaat
    24241 cgcttgatac aggagaaata gccagatagc tgcaaataag tactttttcc catccatatt
    24301 gataaaacct tgcgtctttt cgtgaaaatt gaccgtggta ttagcaggta caagccatgc
    24361 tgcactcagc cctagcaaaa cacttgaaaa ataaaataaa ggaaaataaa atacgcctaa
    24421 tattccaagc aatgaaccag caccaccaat cagcagagcg atcatcagca acgtgtaact
    24481 atctagacca aatcgtagac tgttgactaa aaatagtcca gtcatccgaa aggcataaaa
    24541 cagcgtaaat ggcaaaatcg tcagccaatt atgcgagtct gttagtccca aaaataaaag
    24601 ataaggaata aaaataaccg tgttacttaa gataaagggc gttgtttgtg taaaattacg
    24661 cccaaatcgt ttgagttttt cgaacatgac aatggctcct taaacagtct tataactaat
    24721 ctgctcttcg attttagcat taaaggggaa ataaaccaat tttacagaat atattcttgt
    24781 aaaaaaaaat acagaaagaa gcataagctt ctttctgcat ttttacggta cttgattact
    24841 caagcagaca agcccttctc cacaaaagtc ttgcccgaca cccctgcatc cggcaggtga
    24901 taaagataga aatcaattat cctgtgcctc caaaatcaat taggagctct gtaaaccaga
    24961 gtccttctcg acccgtcgca taaatttact ttaacacagt tcctatgttt atgcgagagc
    25021 ttttttcatt ttataatcga ccatttgaaa tccttgaccg atatctgaaa taagttcttc
    25081 tgtaatctca aatccttcat gcttataaac ctcgattgct tgatgattcc cctgattcac
    25141 tcgcaaaaag atctctcttt cctttgtttg cgcagcaagt tcttcatacc agcgaaaaac
    25201 tgaagaagtc aatccttgac cacgtacttt atttagcaaa tataatttac ttaaataaat
    25261 ttttccattt atctcttcat aagcagtgta accgacagtc ttttcttcgc tttttaataa
    25321 aaagtaggac acaccttctg tcagttcttt ttgaatctgt ttttttgact gataagtttt
    25381 cagcatgtaa tccacttgtt tttgaccaat gatcggcaca aaagcttccg gccatacttc
    25441 ttgtatgact gccatcagct catccagttc attttctgtt acttttattt tttccataca
    25501 cccacgtcct tttttacatt ataaatgacc ttgcgcttga tggaataaaa agagcatgat
    25561 catgctatac acacccaccg accatggttt caagaaaatc acaatctgca taaattccct
    25621 aaaagataat ttcgtcaaac cagctactag acagatcaag tcgtctggcg caaagggaag
    25681 cagcaaggta acaactagta cttttttaat atctttcgtt tttcttgtca gcaattcatc
    25741 aaatttctga tacttttttg gcgataaaat aagctggaca aaggctacgc catagtaacg
    25801 gacaagcaaa aatccgattg cttccccaat cactaggcca atacaactat ataaaagccc
    25861 aaatccattg ccaaacatca gcatgcccgc tactgaggag atccctcccg gcaaaatagg
    25921 aatgatcact tggatcactt gcaacagaac aaatatcatc actgcatact tgccaaattg
    25981 ctggataaac gcttgcaaag acgtgctcga tcgaaaaatc ccatgatgat aagcataaag
    26041 aatcaacaca aagaaaaaaa acagaccaat aatgggcatg atctgaagac atttttgtaa
    26101 aactgatcct tttttagaca tctatattcc ccacatcttt tttcatttat taaaactgcc
    26161 tcctt
//
LOCUS       DAYYEF010000037        25566 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000037 DAYYEF010000000
VERSION     DAYYEF010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.038"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            151..279
                     /locus_tag="ACHA1B_001784"
                     /pseudo
     CDS             151..279
                     /locus_tag="ACHA1B_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
     gene            393..632
                     /locus_tag="ACHA1B_001785"
     CDS             393..632
                     /locus_tag="ACHA1B_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702545.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            744..938
                     /locus_tag="ACHA1B_001786"
     CDS             744..938
                     /locus_tag="ACHA1B_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702546.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYINDMQITGKEKACLLGSMKNFE
                     QLRRTYVKTSSNCQLLLEVS"
     gene            1024..1695
                     /locus_tag="ACHA1B_001787"
     CDS             1024..1695
                     /locus_tag="ACHA1B_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFM8702547.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQQEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1748..3724
                     /locus_tag="ACHA1B_001788"
     CDS             1748..3724
                     /locus_tag="ACHA1B_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFM8702548.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            3739..4491
                     /locus_tag="ACHA1B_001789"
     CDS             3739..4491
                     /locus_tag="ACHA1B_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFM8702549.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            4507..5262
                     /locus_tag="ACHA1B_001790"
     CDS             4507..5262
                     /locus_tag="ACHA1B_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin N-terminal domain-containing protein"
                     /protein_id="HFM8702550.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNEETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            5275..5535
                     /locus_tag="ACHA1B_001791"
     CDS             5275..5535
                     /locus_tag="ACHA1B_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702551.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            5532..7622
                     /locus_tag="ACHA1B_001792"
     CDS             5532..7622
                     /locus_tag="ACHA1B_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HFM8702552.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            7649..8113
                     /locus_tag="ACHA1B_001793"
     CDS             7649..8113
                     /locus_tag="ACHA1B_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702553.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            8110..8352
                     /locus_tag="ACHA1B_001794"
     CDS             8110..8352
                     /locus_tag="ACHA1B_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HFM8702554.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            8370..8672
                     /locus_tag="ACHA1B_001795"
     CDS             8370..8672
                     /locus_tag="ACHA1B_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702555.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            8742..10805
                     /locus_tag="ACHA1B_001796"
     CDS             8742..10805
                     /locus_tag="ACHA1B_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702556.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            10805..13417
                     /locus_tag="ACHA1B_001797"
     CDS             10805..13417
                     /locus_tag="ACHA1B_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirD4-like conjugal transfer protein, CD1115
                     family"
                     /protein_id="HFM8702557.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            13414..15945
                     /locus_tag="ACHA1B_001798"
     CDS             13414..15945
                     /locus_tag="ACHA1B_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pLS20_p028 family conjugation system
                     transmembrane protein"
                     /protein_id="HFM8702558.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            15995..16327
                     /locus_tag="ACHA1B_001799"
     CDS             15995..16327
                     /locus_tag="ACHA1B_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702559.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            16328..16921
                     /locus_tag="ACHA1B_001800"
     CDS             16328..16921
                     /locus_tag="ACHA1B_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702560.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            17084..19108
                     /locus_tag="ACHA1B_001801"
     CDS             17084..19108
                     /locus_tag="ACHA1B_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB4 family type IV secretion system protein"
                     /protein_id="HFM8702561.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            19108..20307
                     /locus_tag="ACHA1B_001802"
     CDS             19108..20307
                     /locus_tag="ACHA1B_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFM8702562.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            20323..20967
                     /locus_tag="ACHA1B_001803"
     CDS             20323..20967
                     /locus_tag="ACHA1B_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702563.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            20978..21784
                     /locus_tag="ACHA1B_001804"
     CDS             20978..21784
                     /locus_tag="ACHA1B_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702564.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            21806..22036
                     /locus_tag="ACHA1B_001805"
     CDS             21806..22036
                     /locus_tag="ACHA1B_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702565.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            22550..22858
                     /locus_tag="ACHA1B_001806"
     CDS             22550..22858
                     /locus_tag="ACHA1B_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702566.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            22860..23282
                     /locus_tag="ACHA1B_001807"
     CDS             22860..23282
                     /locus_tag="ACHA1B_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702567.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            23302..24891
                     /gene="mobP2"
                     /locus_tag="ACHA1B_001808"
     CDS             23302..24891
                     /gene="mobP2"
                     /locus_tag="ACHA1B_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobP2 family relaxase"
                     /protein_id="HFM8702568.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            24903..25238
                     /locus_tag="ACHA1B_001809"
     CDS             24903..25238
                     /locus_tag="ACHA1B_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702569.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            25379..>25566
                     /locus_tag="ACHA1B_001810"
     CDS             25379..>25566
                     /locus_tag="ACHA1B_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702570.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         9541 a         3961 c         5257 g         6807 t
ORIGIN      
        1 gatcaaataa acaagaaccg taggaactac ggggatagct tggtaaataa gaggcacctc
       61 tgttagtaaa gtaatacgct atcaagtatg ctctcttccc aagaagctcc cacttcaagc
      121 gtaagaaacc gttaggttta gctaagtggt gagtagttca caatgacgct tacgaatgat
      181 aatggagacg aattatctgt tgaagatact tggtcatatt tgagtgatta tattgtcagc
      241 gttgaaatca ttgaatttgt agcggataaa gaagaataaa aactggagga ataaatttta
      301 cagataaagg cttagaagaa gtcacgacga ataataaaaa ggtagtatta ccttaggcat
      361 tgagtaagga attcatttag gaggaaaatt agatggcgcg accagtttta gaggcgatgg
      421 atatggatac tttgacaaaa ggaaggtatg tacagctgtt agctcgtggt tattcaccta
      481 aagatgtatt caaatccctg tctaaaggaa cagatatgga aaaagaaaga ttacgaaaag
      541 aattcgatta ttggagaacc cataatggaa tcaaggattt gaaaccagca cggccagtaa
      601 ttaaacgaaa gaaaaagata acccaagact gaagtgtaga gcgtatgtga tcataggctt
      661 ttttattttt gcaaaaaaca aggaaggtag gaaaactcat gaattatgaa gaaatcgaaa
      721 acagaaaaaa agtgtcgaaa taaatggaag aaaagttgct aaaaacgatg aaacaaaaac
      781 accttaaaag attatctgtc atgcaatata tcaatgatat gcagataaca ggaaaagaga
      841 aagcttgttt gttaggttca atgaaaaact ttgaacagtt gagacgaact tatgtgaaaa
      901 caagttctaa ttgtcaacta ttgttagaag tctcatgaca ttcattaata gaattcattt
      961 ttaaaacttt ttctatggaa atgagaaaaa gattttttgt tttgtctgaa agggggtagc
     1021 tggatgagaa aatggttatt tggtttttta ggagtcgctt taatcgtctt ttgcagtgtg
     1081 tttggctatg ttagctacca aaaacatgaa ggagaggtgt ttaagcaaaa tatagaaaaa
     1141 aagatgcccg tagatcaaat caatgcacat gcaaagagtt ataaggagga tgcaacgaac
     1201 gtcaataatg atatgtcttt ggggcaaatg ttgtccatac aacaagaagc aatcgaaatg
     1261 ggcgtcaata aacaagtatt tgcacaaatt cagattcctg cacttggttt agcattgcca
     1321 atttttaaag gggcaaatca atacactttg agtcttggag cggctactta tttttatgaa
     1381 gatgctgaaa tgggcaaagg aaactatgtc ctagcaggtc ataacatgga aatgccaggt
     1441 gttttatttt ctgatattca aaagttgtca ttaggggagg tgatggactt agttagtaac
     1501 gatggcgtct atcgttacaa ggtaacgcgt aaatttatcg tacctgagta ctttaaatta
     1561 atcgatggcg ttcctgaaga gaactctttc ttgtctttgc caaagaaagg agagaaaccc
     1621 ttattaacgt tgtttacttg tgtttatacg tcacaaggaa aagaaagata cgtggtacag
     1681 ggagaactac aataacaagg ttttaatcaa cgtgagtcgt tgaaatatga aatgaggaga
     1741 gtaaaaaatg gcaataaatc ggtatgtaaa aaaagctgga atgcttattg gaatgttagg
     1801 aatcattgca ggctgctttc agggatatcg agcatatgca gaagatgtca cgcaaaaaac
     1861 gccaccagag aaggtcaata tcacggttca taaattaatg tacgatcaag gaacgcaatt
     1921 gaatgttgat attgacggga tcaaaaacga tggttatacg cacgatcaat atcctacagg
     1981 tgtaacgaaa tacaacaagg cagattatgg tgatgttgag tttacgttag gaaatattac
     2041 ggatcaagta ttaccgagag aagattctga tctaaccaac gcgaaagtgg acgagattgt
     2101 acaagatgta gaagacaagg gatctaacag tgagtacgtc aagaatgcaa ccaacaaaat
     2161 tacttcagct gtagatgaaa atggtgagat cacttttact gatcaaccag cctatgtcaa
     2221 ttccaaaggg aatgtatatg tggtttatga aagtaaatcc gctgctggat tagtcacaca
     2281 aaaagcaaaa ccaatggttg tgattgcgcc aatgacagat aaaacaggat caggattttt
     2341 aaaaaatatt catttgtatc ctaagaacat tgtttctaag ttgagttttg aattaacgaa
     2401 atttggtgac gatggcgcag accaaagcaa acaaaccctt ttaaaagggg caaaatttga
     2461 gttatacaag ggcgaacctg gaaaaggaac aaaattgggt gatcttgtat cggatgatca
     2521 aggaaagctg actgcgactg atttgacgtt aggaaaatac tattttgtgg aagttccttc
     2581 ggaagttgta gtgggatcag atcaagaacc aacagcagat caatatttat taggcgcaga
     2641 cgctcgcaac gatgcgcaca ataaattaac ctttgaaatt acgaatgatg gcgtgacaag
     2701 tgacttaaaa gcttcatacg taaactataa agcaccagtg atcgataaaa cagtaacaaa
     2761 tggaacagga caagaacatt ctttccaaat tggtgacgca gtaaattatc aaggaacgat
     2821 tcatattcca acagacattg caggtggcgc agacggtatc acagtaaacg gtgtgaaaag
     2881 tgaaacttct ccttacagtg tatttaaatg gggagataca gcaggacagg gactttctta
     2941 tgtcgctgct aaagcaaata tcaaagtaac aaataaagat ggatctgtgg tattaaaaga
     3001 aaatacagat tataaaatcc aaaattcaga aaatggcttt gtgatcgatt ttatcgtgaa
     3061 taatggccaa gtaagtgata ctgtagcaag tttacacgga caagatcttc aaatgactta
     3121 taacatgtat gtaaatgaca gcgcagctgt tgccaatcca ttaacaaata gcgtggattt
     3181 cgtttataac aacaatccat ttaatcagga agaacaccac gaaaaaacga aagctgacgt
     3241 tgtgacttat ggtgcaaaat tcttaaaagt cgatagcgga ctatttggaa caggaatcaa
     3301 agcaacaccg cttgaaggcg cagaatttgc tgctaaaaac gcagaaggaa aatattatgg
     3361 tggattagtt gatacggata aagacggtgt caaagaagca gtatgggtag acgatgtagc
     3421 aaatgcagcg atcctaaaat cagataaaga aggtcacttt gaaatcactg gtttaactga
     3481 aggtgaatat tcactggaag aaacaaaagc gcctgaaaac tatcaaaaat taacgaaaga
     3541 gatctctttc aaagtagaca aagattcata caaagaagaa aaccgaatca cgatcaaaaa
     3601 caatcaaaaa gcttccgtac caatgaccgg tagcaacggt tttcaaacgt atgtattaat
     3661 ctcttgcttg ttgctaggag caggggcact ttctgcagtt gtttacttta agaagaaagc
     3721 ctagaaggat caaaaccaat gattatcagg aagcctaaga aaaagcgaat catgggtaaa
     3781 tggatcattg ctttctggtt actttcagct gtaggtgtct tacttttgat gcctgctgaa
     3841 gcgagcgtgg cgaaatacca acaaaatcag cagattgccg caatcgatcg aacaggaacg
     3901 gcagcagaaa cggattcttc tttggatgtt gctaagattg agttaggcga tcctgttggt
     3961 attcttacaa ttctaagtat ttctttaaaa ctaccaattt atgacggaac gtccgacaaa
     4021 attttagaaa atggtgtagg tattacggaa ggaactggtg atattacagg aggaaacggt
     4081 aaaaatcctt taatcgcagg tcatagtgga ctttataaag ataatctttt tgatgattta
     4141 ccttcagtaa aaaagggaga aaagttttat atcaaagttg atggtgagca gcacgcttat
     4201 caaatcgatc ggattgagga agtgcaaaaa gacgaactac aaagaaactt tgtcacttac
     4261 ttagaatcaa atcccaatga agatcgagta acgctaatga catgtacgcc taaggggatc
     4321 aacacacacc gttttctagt gtatgggaag cgagtaacct ttacaaaatc agaattaaaa
     4381 gatgaagaaa ataagaaaca aaaattatct tggaaatggc ttttaggaag tactgttttt
     4441 ctttcagtca tgatcattgg ttcgctattt gtttataaaa agaaaaaata aaggagggta
     4501 accaacatga gaaatagaaa atggctattt gtttgtgcag ccgctctttt ttctttcact
     4561 gcctacacac agttgacgtt tgcagacaga caagaaagca cggatagcac agaacaaaca
     4621 atccaaacgt cagatagcag cacgattcaa agcagcgatg aaaccgtcga ttcgtcaaca
     4681 gttgattctt cagaagaacc taaaattgct gaagacgatc aaatagtcaa acagaccatt
     4741 cacgttcaaa agattatttc ttcagaacaa ttagacaacc aggggcatga aaaacaagaa
     4801 ggagtaaatg gcgcgaagtt ttctgtttat gatgtatcgg acattttaca aaagatggat
     4861 gttaaggatc tcactactga ccaaattgaa tcccaattaa aaaatcgagt gaaaaaacta
     4921 tccagtgatc aattgaagct agtttctaat gaagaaacaa agacaattga tcaacaaaca
     4981 ggtgtctttg aattctcggt agaagtacag gcaaatcaga aacaagctta ttatattgtc
     5041 aatgaatcaa gtcctgaaaa catttctaat agcgaggata ttttgctatt aacacctgtt
     5101 tctgataaaa acggtgaatt cttaaaggat gtgtggatct atcctaaatc agaagcttcg
     5161 caacctaaag aagaagtaaa aaaaatcgtt tctactggcg taaagaaaaa cttctttgag
     5221 aattgttggg attttgttac tcacttgttt tctagagatt aaggaagaaa taaaatgaaa
     5281 ctgatcaaat tattattatt caatttttct tgtttaaccg cagtcttttt gtactgcggt
     5341 ttattatttt ctaaactatc tattttgcca agctaccaac tatacctaat gaggatttta
     5401 aacataccag ctgcttccat gccgctagat attatggaaa agctcattag gaatccatta
     5461 tttactacga tcaatttgat cgttattgtc ggaatttcac tagtcattta taaaaaagag
     5521 gggatgaagg gatgaatttt aaacactcgt ggacaagacg gttaaaatat gtttttccca
     5581 taatgatgat gttaggtaca ttgtttgggt taaaaacagc caatgtcttt gctgaaaaag
     5641 ttattgtcga tccgtcaaat ccaatccaga acgtaaagaa taattttatt attccaaaag
     5701 atgttcctaa tgcaaaaaca aatattactg taaacggagc gtcaaaagtt tacaaatatc
     5761 atgttgatgc caacaaaggt ggttttacag acgactacgt aggattagtg gagggaaaca
     5821 aaaatatacg ctatccttct ttccaaaaag aatacggtga aacaaacctt gttttagaag
     5881 gcgtaacaac caacaccaaa gtcaatattg actatggaaa aatcggtacg tataacggga
     5941 aaaaagtcaa tatcaagcta gttctatcta atattcactt atactcggat acgttgccgt
     6001 ggaatctact agataacaac tatacaaaaa ctcattttcg agacgatggc tataaaaata
     6061 cgaatggtgc aatgagtaaa tctaaaaaaa gaacagtact ttggatctca gacaatcttt
     6121 tctcaggaat tgtttaccat tcaacacaaa tgaatgtgca gctagtagcc acatatgagg
     6181 acggtagccc cgttcaattt tcaggagata catttatcag ttttaactct ttgaaccctg
     6241 caggaggaaa aagcacggat cttaaaggag aatatgccca ctatgacaaa atgaatacga
     6301 cagattggta tgtcagaaaa gatacggttc tttcagaatt taaatctttc tacaacaatc
     6361 tgaacgtggt aggtggccac ccaggaggaa gctctaagct gacacaagcg gataatgatt
     6421 tcaataattt gcatgataaa ttaggagatc cgaagtttgg tcaaggtact gtgtccttta
     6481 aaatatctga agcaaatccg acgtttgtga ttggttcttc taatgttcaa acctggttta
     6541 ctttatcttc tgcgacaatc tttagtgttg ttcctgatca acctgaaaaa acaggggttg
     6601 ataaaaatgg aaataacgtg aacgataaaa tgttgcaagt aggagacacg attcaatatc
     6661 gaatcaaaca gaaggtgaat cgattaggag tggatttact agcggtttac gatcgatttg
     6721 agttaatcga taatttacca aaagaagtaa attacgtcga tgcacacgtt gaaagtggta
     6781 caaataaaaa attcgatgta tctggtgaag tgacctatga caaaacaaaa caccaggtaa
     6841 aatatgcagc gaaagctgat acattaaaaa atcgaatgaa gtataacggc gaaacttacg
     6901 aattagtgat caatgtaaaa gtcaatgaat tggccaatca aaatagtgta gccaaaaatc
     6961 agggaacgtc gatcattaat aaagtagaaa aggatacaaa tatcattacc gtttatttcc
     7021 ctaaaattcc agtgaaagaa gtacaacaaa atggaaaaga tgtaaacgga cgaaatgacg
     7081 gtaagaaggg tacgccgaca gctcctttaa acgcaggatc tgaagtacaa tatctagtca
     7141 cacaaaaatg gcacacaaaa ggcgtagacg ctgcgtcaga tcactacaaa caatttagta
     7201 ttcaagatcc aattgaagct cgtttgacat ataaagaagg ttctgcgcaa gtaatagata
     7261 agagtaaagg aaaagatatt acttctgaag gcacactaac ctatgatagc aattcaagaa
     7321 cgctgaagtg ggaagcttcc gctgacttct taagtaacaa tcttttagat ggacgagaaa
     7381 ttcagctgat atttacagct aaaactccat tacaatcaga aaaaaatatt gataaccaag
     7441 ccgtagtagc agtagataat gtttctaata aaacaaatgt tgtgacaatt ggggttgatc
     7501 ctaacttgcc acaggtcatt gttcctaaaa caggttctac acatttagta acgatttcag
     7561 cggtcagctt actattactt gtgttagcaa cttttagtta tgcggttctg agatacattt
     7621 aaaataaaaa aacgaaagaa tgaataaaat gaaaaagtta ataatagtag ttacttcctt
     7681 gattgccatg attgttattt tagtcggatg tagtaatgaa aaaaataaac aaactaatca
     7741 agataatggc gtattgaaat caggaactat gtggaaagaa gaagtaggtg gtcttgttta
     7801 taatttgaaa attatagacg agactacctg ggaatactct gagagtgtat ggcatccaga
     7861 tcctgtacaa ataacagtca agaggcaaaa agactataaa ggtttagaaa gatacaaaat
     7921 agtagattca gctggtgtta gggaatttat aaacaaatct gattctttat ttattgttgt
     7981 tccctatgag aagaatggcg taaaaaaaat aatttttctt ggatctagca aggatgaaaa
     8041 gcgaacgaaa gagaaattga ttcacgatgg atcacaatcc aataaatata agttacaaaa
     8101 gactagcgag tgattgctag tctttttatt tgtcctgaag gaggaatcac agtggcaaaa
     8161 gctaaaacgc catttgaaaa agccgcgtct aaaatcttag aacgccgcgg tgtatctgaa
     8221 acacagtgga aacaagaagt ccttgaaaaa gcacaatttg acctattacg gggaaaagac
     8281 aaggacttag aaggatatat ctatcaacgt gaacgtgaaa agcttgtttt cgatgaaatt
     8341 attaaacact aaaaggagcg aacaatttta tgtttgaatc aattacaatg aattttttaa
     8401 cacaaccgaa agtagtagct gcggttgata tttttagagc attacaaact gccgcaacta
     8461 gtttaaaaaa caatctgatg atttttgctg ctgctgcggc cgttgcttcc attgttattg
     8521 ggggtctttt cttcctattt ggacgaagag gagctgaaaa tgggaagatg cacgtaggct
     8581 atgtattgat gggggtagga gttattttag cagcagcttc tattgtggtt tcgttatttg
     8641 gattgtttgg acaaacacct caaggattat aagaaagtaa aaaagtagga gtaagaagta
     8701 gtcgatactt tttactcctt ttttatgaaa ggagaatact catgtacttt acgattgcag
     8761 gcaataccaa aacagataaa gagttaataa aaaaagcaac gaaggaagta ggaaagcgta
     8821 cttctttttt accgaaaaca attaaatatt ctgtcattga aacggaagaa cagctacatg
     8881 tgttagggaa agtactggaa cacgaaagtc gatcttctgt taagttgact ctcacgttac
     8941 atgacacaga aggaaaaata gagaaagctg gtacagaata cgtttttggc ccactggatt
     9001 atcaaatttc agaaggtttc tatcctacat tgatggattt aatccgcctt gatgtgttta
     9061 aagaaacgga tgaaactatg agtgtggaag agtcttatcg aaacgaaaaa cttttacaag
     9121 ttttagaaga agagttagag agcgaccaaa gaaaagtgaa tcaagggagt gaagtcgaag
     9181 taaatgaaga agtaccatgg gaacgaccaa tatttccaaa gaaggagtca aaagaaaaag
     9241 agacagtcta tgttgacgaa caagctgata ttccgactca gaaatcgata tttgaggaag
     9301 agaacgatgt gatgggtcaa ttggaggtag atccctttga agaaacaatg gaggatgaag
     9361 agacggccga agtagaagtt gatccagttg aagcgaatga agagtcaaca tggactgaag
     9421 gggattctca ggaatatatt gaaccactta tcagtgaaga agtagaaaaa aacgaaatag
     9481 agatacaaaa ggcaactgta tttgattata ttttggatca atatccgcca gagcatgaat
     9541 ggatgaaaga aaaaaacaaa ttatttttaa atgagcttta ttcgaaatat caattacccc
     9601 aaacctatca agcattttta gagagtaaag aagaattaat ctcacagggt aaaggcacac
     9661 ttttagaaca gttagagtct gtccaatcaa caaattggca tgagcttgca caagaagatt
     9721 tattagccac ctttgaagaa cgtcaacaag aaacagatca agaaattaat gagtatgcga
     9781 cggaacagtc gtctaattgg gagaaagcaa aagaggaact aaataaagaa gaacagcgag
     9841 tgattgaaga agaagtacaa aaaattaaag agcgatacga aaagaaacgc gacaatgcgt
     9901 attccttgtg tgtagcaaag atcaataatt ttactcagac gaatcaagaa gcgttatcga
     9961 aagaaaaaga aaacttgtta aaagaacgta ttaaagaacg aaaagaagaa ttttaccgag
    10021 gtttgcgtac agataagcta aagattagca aagaattaaa tgaacaactg aataagctat
    10081 atcaaacaac gactgaagtt cttatggaaa aatacgaaaa gatccagcaa gaattacaag
    10141 tgcaaattcc aaaatggaaa aaagagtatg aaattcaaca acaagaattg aaagaacaag
    10201 aagaaaaaca acggcaaaaa gaaaaagagc gcgaacaatt agaactaaaa aaacgtgaac
    10261 aggatcttgc ggaacaacaa atggcaatag aaaaacaacg gttaaaccaa gaaaaggaaa
    10321 aagaagcagc tgctcgtaag gaacgtcaag aacaaatgga tacattgcga caagctcagt
    10381 taaattatct agcacaacct caaccaacgc cttcagtagc tgctgttcaa accccaatga
    10441 acaaccaaac aaatctaact ccttcaccac agcgttcctt taacggatgg atggtgggat
    10501 gtattgcaag tttaagcttg cttctaggtg gaggaacagt atttgctttt aatcatatca
    10561 atcaatcttc acaggctgat tctgtggcca caacgacgtc aatcaaggaa gaagcccaag
    10621 aacaagcaag aaaagagtat gaacaacaat tagaagaatt attgaatcgt accaatcagt
    10681 caacaacaga gtcaagcatg gaaaatagca aagagagtga ttctagtaag gctaaagaag
    10741 gatcaagcga ttcaactgta caatcaaaca cttccgaaag ttcagaatca aatgaggtga
    10801 aataatgcgt gttagagaaa caacgaagcg aaaagacaaa cgattcaatt tagaaaagaa
    10861 taggtatctt tctcatttct atcgctatac tccctcagga gaagagctac cagaaaaaca
    10921 tgacaaacgc atttcgaaaa agatttttta tagtggactt gtatacctcc ctttagagta
    10981 tttagtaaca agagtaccag aagttttcaa ccgattggaa attgttaagg gaagcttaca
    11041 aggaataaat ctgtttcaat tacaggaaat gccacaggtc tttcattttg attcagctgg
    11101 tttttggaat ccatttactc ctacaactag tttgggtaca cgtttagcaa tttcgacagt
    11161 ttgtgtggtt ccagctgtac ttatgggatt gaaaatggac atgtggtttc gtcctctagc
    11221 agatggacaa aaaggggata atcgattaat gaccttaaaa gaaatccaac agatttatcc
    11281 gcaaatacct gaaacaaaaa ctacttttcc aggttatgga ggtattccaa tcacacatta
    11341 caaaaaatat tggtacattc aaacagatac tgttaatacg tgtattgttg gtacctctcg
    11401 atcagggaaa ggtcagattg aagtgttagc caccattgac aatttatctc gtgcagaaaa
    11461 acaaagttca atggtcgtta atgatccaaa aacagaatta tatgttggta gtaaagatga
    11521 actagaagct agagggtatg atgtatatgc ctttaatatc accgatccac tgcaatcaat
    11581 gagtgataat ccattggcac tcatcgtgaa atactggaaa cgaggagaca tagatactgc
    11641 aacacagtta accaatactt tcacaaatac gatttattat gatgccaacg cttcagataa
    11701 caaatacttt aacgaaaacg cgcagaaagc tgtcaatgcg cttatttttg cgttgttaga
    11761 acaagctgat caaacaggag attactccaa attgacaccg aataatctcg ttgagcttct
    11821 ttctgagatt ggcggtttta attattatcc agatccagac aatgaattca aacagttgaa
    11881 tgccttagat gaatttatga atcagttgcc acctggaaac attgcaaaaa aacaatatgg
    11941 ggcaacgaaa attggatctg ataaagcgaa gggaaatatt ttatcaacgg caatcacggg
    12001 attgaatcca tttactctaa cgaaaattgc aaagatgact tctcaatcaa cgattgatta
    12061 taaatcggtt gggtttccaa aatacttaga tttgaaatta catgaaagtc ttttaaatca
    12121 acgagtcgta gtagaatttt atcataaggg aaagaaattt catgaagaac gtgtcaaagt
    12181 aggctataaa ggattttgtg aaatcaattt tgattgtcat ttagttgcag gtgatcaagt
    12241 ttgtttaaaa tacgatcatc aaggaaaaga atatgtggct tggtatgaat tttctcaaag
    12301 agtattgaaa gacgaagagg gtaatatcgt ttatcggaaa aaacgaggag aaacccattt
    12361 gccagaatta gaaaaagaag ccgttctaac attagatgag gagaaaagta acttattagt
    12421 agagtctatt cggatgcact ataccgataa accaatggct atttttatgc ttacacctga
    12481 ttatgatcca tctaaccata tcattgttag tatttttctt agtcagttat ataaagaatt
    12541 atctacgcaa tgtgttaaga ctaaaggaga taaatgtcac cgcaggattc attttatttt
    12601 agatgaattt gggaatatgc caccaatgga taatatggaa ggaatcatga cggtcacagc
    12661 tggccgaaac atgttgtggg atctgtttat tcaatcttat cagcaacttt atgcgaagta
    12721 tggagaacaa aacgcagcga ttatcaaaga aaattgtcag acacatattt atattatgtc
    12781 gacagatgat aataccatcg aagaattttc taaaaaagtg gggaataaga cggttgaaca
    12841 agagaacagt accatcaatt cattaggtat gaatactcat atcaatcgca atgttgattc
    12901 agatcgtatc ttaactcctg aaagaatttc tactttttta gaaggtgaaa cgattgtact
    12961 cgctccttta aaacgacaag atttgaaagg tcataaaata cggccgtatc ctatttttaa
    13021 tcatggggaa acgaatcttc cttatgctta tcaatatatt gaagatttca atccatcgtg
    13081 ggatatcaat gatatagaca tacattgtac acatgcggac ttggatctta aggctttaca
    13141 aattgattat gattatttcc taccagatga atatgctaga aatctctatc atggactgca
    13201 tgatcaatta gaagaaaaaa acgaagaaaa tatgttttat aaaatcgttc aatctcttga
    13261 gaatgagacg gctaaaaaat tgttaattca attttacgaa gaacaagcag cagatcgact
    13321 tcaagaatat gttgaaaagt tgatcaaaaa taaagaaatt tctgaaatga ttgggaaacg
    13381 gttgttattg gaatctgaaa aggtggtgaa agaatgatca ttggaggaat tttttctggc
    13441 atagccgact ggtggtcagg cttattcgga gaaggggatg caaaccccaa aaccgtaacg
    13501 aaagtcttac aagattatgg taattatctg cagtatcaag atgtatttag ttggatttgg
    13561 aacacttttc tgtggggatt gattaaagga ttatataatc tcaatacttt actagaaaaa
    13621 accatttatc aaagctttga tttaaaagac ttattgaacg ccgctggggt aaatgcacta
    13681 tttcaaagtt tgattagtaa ggtattggct cttttttgtg tcgtcacatt aatttattta
    13741 ggcttgaaat tttttatgag taaacaccca ccaaaagtca aaaatatctt ggttaattta
    13801 tttatggcca tgatcttgat ttttggtggg agttctttaa tcgatgaagg gttaaatatc
    13861 agtaaaagct tttacggaga cgtcactgca gcaaataaag cagataaaac gggttcacct
    13921 gcttttcaaa ttattcaaaa taatgtgatc gatgtcagta cattactagc aactgacccg
    13981 aataaagtag aatccctgcc aacagacaaa agaaatgctt taacagcgaa aaattttaaa
    14041 acagcgaata tcaatgggat tattactcct aaacaagcta aagaaatggc ggataaagat
    14101 aagagtggtt tatcagattt acaaaaggat cggttaagag cgttacaata ccgattggaa
    14161 ctagatgata atgggaaaga aattcctgtt caaattagtg acgaaggctt agcaaaatat
    14221 gtctatactt cagggtatcg tcgatacagt agtaaaccag gtattatctt agctggtgaa
    14281 tcttctttgg cggtggccta tttatttatc ctatttacga tcgttacttg cattattgag
    14341 ctggtattta aaaaattcta tttagtgatt gccgcgtcaa cggactttga gacaggccaa
    14401 cggatgaaaa gtgcgataga agatatttct caatccttct tgttattggc gtttacgatt
    14461 ttagaattac gaatctatac attaatgctt tcaggtatcg gtgatttgca tgcggcagga
    14521 aagatcaatg gattcttgta tgttgttgct ttaattgtgc taactattgc gctattcaaa
    14581 ggctctcaat cggttacgaa gattttcggt gttgatacga gtctgaaaaa cggcagtaat
    14641 tctcttctta gcatgtttgc cttaggaaat attgcgaaaa atgtgggtag cggagctaaa
    14701 aaccttgcaa gtgctggtaa gagtggttta agccatttaa atgatattcg taaaaatgga
    14761 tttggccatc gaaaagatgt tacccctgat aacggggaag aacaatcaga cgataaagct
    14821 acaactgtac ctaatagtaa gaaaacagtt tccgaaatgt tcgggaaagc gaaaaatggt
    14881 gtttctaaag ccgcagaagg tcttggttac gtcaatgaac gtgggttaaa aggaacagct
    14941 gaagatctta cagaaaaagc caaagacacc ttagaagaga aattagacgg cacgagagct
    15001 aaagaattgg ctgaagctgt gaagaatcca tccgaagcac tagaaaaaca aaaagaaaaa
    15061 gcttcagaag tcaaagaagg actaaaagat gcgtatggtg aaggacaagt taatgcagca
    15121 gtaaaagcta atacaacaac cgaaaaagaa aatcaagaag gtatagtgat tccttcagtc
    15181 aaagatcacc aagaagcgtt gcactctaat gaaaattcga ttgaagagaa aaattccata
    15241 gaagaaagaa attcagaaga aggaaaaaat ggacagttac caaaaactga tccagaacaa
    15301 tatcgctata aacctaacag tgaccttgaa aatgagaagc gaatttcaga tttatcaaaa
    15361 gtaaatcaag aagacaaagc agaaaatgag ggacagttac caaaaactga tccagaacaa
    15421 tatcggtata gatctgttaa ctccgaaaat gaaaaacgca tttcagattt accaaaacga
    15481 aatcaagaag tacaaacgga tgaggattcc atcgttctgc caaatgataa tggaatcgaa
    15541 gttggaactg aaaaatcaac gaaaattggt ttacctaagg cacaaaattt accaatgaaa
    15601 gatagtcgtt tgaatcaatt caaggagaat gatcaaagct ttgttcacca atcaactgca
    15661 ggtactgttc aaatgaaacc aagtcgtttg cctgaaaatg gaaatctgac aactgtttct
    15721 tacaatttat ctgaaagtgg tgagacaggg aatgcgtccg ttcaaaatgt tgtgacaaga
    15781 gaagctgcac caaaacctat tcaaaacgtt catacaggtt acaagccagc aaatgtggca
    15841 tttactgcac caacaaaaat aaatgtgaca agagaaacta aaaacaggaa caatgcattg
    15901 aaagaacaac tattgaggga tatcaaacag gatatcaaac cataaaaggc ctacaagtta
    15961 ggccttttat ttatatgaaa aggagaaatc aattatggat aaatatataa acatgaaaaa
    16021 ccctccaaga tttagtggag aatggaagtt tttcgctttt ttctttttag atctattaac
    16081 gcttggtggc tgcttttttt gggcgaaaat ggtcaataat cttgtccact taccactctt
    16141 ttttgcactc ttgaattatg gcttatggat tgcgatagcg ttagtgattg tttggcgacc
    16201 ctataataac ccaggtcaac gacaaatttt tgcgattatc gagtctattt tttttgcgga
    16261 caagaaccat tatcatgcgt tagatcctaa ccgaaattat catggtacgt ataaggagga
    16321 tgaataaatg cgagtcaaag gacaaaattc agttgaaagg aaatccattt tgcagtttgg
    16381 aaaaccagaa gagcgctcta tcttggactt atttccgtat aaatcctgta cagaagaggg
    16441 agtcttaatt actagagaag atcattttca acgttattat cgtgtagttt ctacagacgt
    16501 ggaaggatta aatgaacaag agaaactaga acgaatgaat cagttgacca ccgtcatgcg
    16561 tacgtatgtg ccaacaatta agttagttag tttgaccaca gagacggatc taacggaaca
    16621 aatcgtgcaa aagcggcaat tattagataa aaatcgtatg gaacagtcct taggaagaaa
    16681 tctacaacga ttaaaaaaat atgaaaagaa attagtcgaa gaaatccagg aattgaaacg
    16741 agcagaacaa gaacgtcctg acttaagctt ctttttcgtc attgaaggaa agacaatcaa
    16801 ggatttacaa accagaaacc gtcagttaat gcgatctagt ggcattttag ggttaaaacc
    16861 actctacaaa aaagaattga tcaagattct gtatcgaatg aacaatatga atgatgagta
    16921 ggaatggaga agagagaatg aaatatccgt tgatatggtt agaaaaagat gttccgaagg
    16981 aagagaccac tagaaaattt cctcacactt taagcctggg taagttggga aaagggcaat
    17041 cttttaacca agtaaagaat caaacaagaa gaggtgactg tacatgttag aagcaattaa
    17101 aacagctttt tcaccacaaa atgatcaaaa agtacttgat ccattaaagc aactaggaaa
    17161 tcgggaaata gaaattttaa aatccaaagg gtatgattta gattttttaa aacaagtgat
    17221 gccacaaggt gggttaaatt ttgatgaaga atatgtgacg tatggtaatg gttattcacg
    17281 atgtgtgaca gtttatcact acacaaaaaa tcctacgctt ttttggttgg ccaatctcat
    17341 gaacaatcct catacagtgg ccacactcga tgttagcaca gatgaaaagc aaaaagtgat
    17401 tgatcaaatc aatcgtgcct tagatgaatt aaatgatcga tcagataatg aacgaaaagc
    17461 gactgaccga aataaaagcg cagaagaata cctggaacta gcggaatatg ctcgtaaatt
    17521 gacttctaat ggggaaattt ctaagcaagt caaagtgaga gtacatgttt acggaaacac
    17581 gattcaagaa gtagatgaac gagcgcagga actgatcgaa aatctaaaag ggatggatta
    17641 tcgtgcggtg acttatctgc ataaaaccaa acgagattgg caatcgatgt ttaccatgtt
    17701 cgatgaacaa gctgaatggt tcggaaatat caaagggcaa tcactaccat cgttaaacat
    17761 tggcggaggt ttcccgttcc accaccaaac gctaaaagat ccaggaggga cacaatatgg
    17821 ggaaaccatg acaggcggcc catttgtctg gaatgcgacg tataaaaata gtgtacggtt
    17881 gtctactaat accttgcttc taggaatgat gggagctggt aaatcgaccg ttcttaaaat
    17941 gatcgcggaa gcccatttag ctgcaggaga ctttatttgg ggctttgaaa agggaaaaga
    18001 ctttattcct ttcttaaagg aatataacgg tattatggtg cgtttagacg gatctgacgg
    18061 aatgatcaat cctttagaga tatttgccac acggacgtat gatgaagcat ccagtttata
    18121 tgacgatgga tcagtcaaag atttgaagat caatgaagca gcgtcctatc aaacacactt
    18181 agacaaagtg gtctatcagg tacagttagt gagtcctcag ctaaaaggaa cgatgaaagc
    18241 agaatttaag acctacttaa atcgttttta tgaagagtat ggaacagtac cacgcggctt
    18301 tacttcctca aattcgcgtt caaatacgga gacgcaagtc acaggtaaag atccagaagc
    18361 ttatccgacg ttcaaagaat ttttagactt tttaggacaa ctggaattac caggtgcttc
    18421 ccaagagaaa aagaatcgaa aagaagaaat ggaatccatc gtagaatcct tatgtgagac
    18481 gtatggcatg atttttgatg ggcatagtac gattcgacac cttgaccaac aacagttggt
    18541 cttttttgac attgactcta ttacaggctt agatcgaggg gtacaacaat gtcaaatgta
    18601 catggctatg acgttgattt ggaatcaggc attgattcaa ggaagaagac aacgacgttt
    18661 aattaaagaa aaacaaatgg aagaacaaga cttcaaacgc ttcttggcga tgattgatga
    18721 gtgccataat gcgattaatc cagattttat tgaaacggta aattatgtca caaactttca
    18781 acgagaaatg cgtaaagtag aagcaatgac tgttttagct acacaatccc cacaagaaat
    18841 ggtgccagaa aatatgtctt ctgataactt ctcgaaactg aagaaagtct ttgaattttc
    18901 ttctacgaag atctttatgc gtatggatga atctatttta cgtcatatag aaggattagt
    18961 gggtaaatca atgacgaact cagaattaga atccattcct caacaaaatc aaggagacgc
    19021 tgtgatcaat tttggctcaa aagaaaccat tcgtgttcat tttagtccga acaaacgtca
    19081 attaaaattg tttgatggag gaaaataatg gaaaaccaaa atgaaagttt aatcaaacag
    19141 tatgttaagc gtcgtgcaaa gcggcgctta tttttgtggg tgtttggtac ttctgcaggt
    19201 ttgattacta tattgatcac tgtgtttgtg accctttttc taatacttgc ggcaggttct
    19261 attgataatt ctgattcaag tagtggtggc gaagctttta caggagaata ttcggaaggc
    19321 ttacccattt ataaagaaat caaaggaaga ggcccttttt ctgatgagat tgcgcaatat
    19381 gctgtaggtg cagcagtgaa gtataaatta ttaccaagtg tgatcctttc gcaatacggt
    19441 tatgaatcag cgtttggtac gtcggcgtcc gcaagaaatg atctcaatta ttttgggatt
    19501 acgtggtttg atgggtgtct gtttcctaaa ggaactgcgc gtggaattgg tggcattgaa
    19561 ggtggctggt acatgaagtt tcccaactca aaagctgcct tctcctatta cggctttatg
    19621 gtagccacac aatcaaattt taatgcttgt gtcggaaata aaagccctgg cgcaagctta
    19681 ttgatcttag gacgaggagg gtatgccgcc gcaggaatta ctgaagacag tgcctattat
    19741 aaaaattgta tgtctattat taatacaaat aaattgatgg agtacgatga gtttgcgatt
    19801 aaacactgga gagaaggcgg cggaactggt ggtacgatta caggaagctg gggcaatcca
    19861 ttcccaggaa gtagcttaga taaaaattcg ttcagtggag gacaactttt tgggaaaaat
    19921 ccaggaggag aattccgacc taacgggttc catgatggac tagactttgg ttcagtcgat
    19981 catccaggaa gtgagattca tgcggttcat ggcggaaaag tcgtgtacgt tggcaatcct
    20041 ggtatttcag gtttgggtgc gtgtgtgatc gtgattaatt acgatggctt gaatatggtg
    20101 tatcaagaat ttgcaaatag tacaggaaat tctcgagtga aagtaggcga tcaagtgaaa
    20161 gttggtcaag taattgggat acgagataca gcacacttgc atttaggatt tactcgaatg
    20221 gattggcgtc aagcacaagg acatgcattc attgatgatg gtacatggat cgatccgtta
    20281 ccatttttga atagcagcaa aaaatagatc aggagaaaaa atatggaaaa taaaacctta
    20341 aaaatcgtct taacagctgc aattagcgtt agtttaatcg gcaatattgc gttgttttgg
    20401 cagcttaaag aagaacaaga gacaaatacc tataaaattg aagaagtggc taaaaacgcg
    20461 tctgataagc tcaaaaaaaa ttcttctgag gcacaggcga agatcgacaa gttaaatcaa
    20521 accatcaatg agaaaaacca agaaatcgat cagctgaagc aacaagatgg cacaaaagca
    20581 aaagaggaag taactgaagc acaaagaaag acggcagaag agttcggtca attggccatt
    20641 gataaatcat taagcagaaa tgaattaacg gaaaaactaa aagatgtcgc aacccaagaa
    20701 gtgatcgaca aattaagtcc tgcagacgat gatcaccaac atgacgacta cggaagttac
    20761 tcttttacat taggtgacgt gcaaacttac gctcaaacaa gcagtgtaaa agaggaacaa
    20821 aattttgtcg tatttgttga ttatacaatc ggcaatcctc aatttaaaga tgtcaaacca
    20881 caaaaaataa aaggtggatt aactgtcact gaaaaacaag tagatggtca atggaaagtc
    20941 acagacttta gttatttcac tcgttaggag gaagaaaatg agtaagaaaa aaggagcaag
    21001 acaacgtttt aaaaaacgaa aaagttatct tagatggctg gggatcttta tgattctcgg
    21061 ctttttgatt cttgctagtc cgatttacac acataaaaag gtagacatac cagatgaagt
    21121 aagcacgaac gcatttttaa acacgaagga actgacgatg gtttcaaaag aaaaaggagc
    21181 gaaccagcaa ttagtttttg aatttgcgat cgacgatgaa gatcagagct tattaaaaga
    21241 actagctaat cttaattatc gtgtagaagt aaagacagct aaaggggatt atcaagcaat
    21301 aaaagccaaa gtgatcaagg tgtctgatga ttattttgta gtgaagttag cacatgtacc
    21361 agaagaatat atcgccatgc gtttaaccat tattcctgaa aaaattgatc caaaagtgga
    21421 tatgcaagaa ccacaagatc tgatttatta cgttcacgaa gataaggtta aagatcaagt
    21481 gaaagatgaa gattatgaac aacatgcgat caattacaaa gtgaaaggat acaaaaaaga
    21541 acaaaaagca gcacaaaaac aaatggaatc cttccaagca accattgatt tgaatgaaga
    21601 attagtgaag aagctaaaag atcaattgcc ttatcaagtc gcagatgatc aggaaaatac
    21661 tgaaaacaag attaatagct accagcaaga aattgaaaca tcgaaaacgc aaatgaaaga
    21721 tcaagaagag atcattcaaa aacttcaaga aaaaattgat cgtatgacaa aagaaaagat
    21781 ttagaaggac aggtggagtg aaaaaatgaa gcgaacaaac ttggctgaca aagatacttt
    21841 cgctgagcag aaagtattga ttaaagccta tctcaaagtt gtaaaagcta aagaaatatg
    21901 tcgagaagtg aatttatcta atacaacaat atctgagttg aagaatggtc gaaagaattt
    21961 agatacttta aaattcagat catttgaagc tctatatgta gctgctaaaa aatattttac
    22021 agctgataac aaataaaaaa caggagtatt ttatgtgaaa aaagtatata aaaaatgctt
    22081 atgaatcagc tatatcacct taaccatttg ttaatgagat gggagaaaac attaaccacg
    22141 attctaacgc aaacatcaag cacataaaac atttaacact cctcctttct ggctgaagat
    22201 ttcaaccaaa caggaagaca gcgtatcaat tatagcatac actttttctt aaattcattt
    22261 ttcatatgac aaaatatttc cttctaatcg acaaagttag aaggattttt tattgtctaa
    22321 atacacaaat aaccttaatt tataaagagc ataaggaaac gtgggaacac tttttaaaaa
    22381 aagtgttcca ataggctgtg cctattacgt ttctcaaaaa taattgtggg aacaaaatat
    22441 ttaaaaatag gatagtgaaa ggatagcaaa ggatagtaaa aggatagaag caggatagcg
    22501 aaaaggatag gctccttttc gctatccttt ttaaattgga ggaattaata tggaagtaag
    22561 aataagaaat gtagatgaga aaatcgtaag agaaattgat cgaagatgtg acgaactaag
    22621 taaccgaacg ggtaataaat ggagtcgtaa cgattattta aagctactcg ttgaaaatga
    22681 ttttgatcgt cctttgatgg aatataaaca agataaattt gatcaattat taaatcagtt
    22741 aatagataaa ttttcttttg ttcaaagtca taatacaaaa gtattagaag aatatatttg
    22801 tcagaataat caaattatcg aacttttaat tgaacaaagt agaggaggag aagtttaaca
    22861 tggccaaagt tatagacaag catatttatt tttatgaaac acatatagat gttctagatg
    22921 aaattattgc aactcatgca gaggttaaaa actatagtga agccgttcgg tttctatgta
    22981 tgaattatga ttcagaagtg gagaaaaaag taaattccaa tcaagcaaag ttgaatgcaa
    23041 tgggaaaaga aatttctatt ttaaccgaaa tggtttcaga gtttgcggat ctccatttga
    23101 aagatacagg gattttaatt ggtacaaatt caactgttta ccaagaagca aaagagcgtg
    23161 tggaaggcaa gataaaagca aatcaaacga agaaatattc tcctaagata aagaaaacaa
    23221 taagcgaatc agtgactaca aaaagtgaag tatttgatcc aacaaggttc ttaaaacgat
    23281 aaaaattaga aggagaatgt gatgagtaaa tcacctgcag tcattctcac ttgtcaattt
    23341 accttgccca ataaaaaatc tttttcaaca tacattgatt atatgacaag agaaaaagcg
    23401 ctggaagaaa aggaacgacg tacgcccgag gaagaacagg aactgcgtct aatcaagaat
    23461 gctttagagg atttttatat tcctgaagga gaaacttttt cggagagtaa gacgggtaaa
    23521 gaattcagcg aaacgtcgaa tgaagcgcaa tcgttgatga aacatggaat caattttgac
    23581 aagttagaag aacaagattt taccaaatat ctttcttata tgacacgtca ctatgcgtta
    23641 gaacaaaaga aagtactgac gcatagtgaa caaaaagaat accaacgctt gaaccaagca
    23701 ataaaaaaat atcaaacaga gccacacaaa aaagcttcag gaaatcttcc tggagttttt
    23761 tctatggctt cagacgaagt gaaaggaagt gatctgaagg agatcaagca aaccttccaa
    23821 agaggacaac aaaaaggctc aatcatttat caagatgttg tctctcatga tcattcgtat
    23881 cttgaaaaaa taggattgta cgatcccaaa acagatactt tagatgaaga aggtttaaaa
    23941 gcagctggaa gaaaaatgat ggagacattg ttcgagaaag agcaactgaa tgaaacaggc
    24001 tactggatgg caacgattca ccgaaatacc aaacatatcc atattcattt tgcagttgtt
    24061 gaaaaaaaaa atacgcgtaa accatacact gagattgaaa atggtgtgag ttatatcgta
    24121 ccgaaaggga agagaaggca agcaacatta gacgaaatga agactaatta tgtacatgag
    24181 ttagaacgtt tttcttatga aaaaaatcga atgggtatgg agaaacgaaa tttattgaca
    24241 cggaaaagtg atttgcgtaa caccttaacc aaagtagtga aagagccagt acgttatgat
    24301 cgacacgcaa tgagcttatt aactgaagta tataaaaact tacctaaaaa gcgttcggaa
    24361 tggcattacg gggatgaaaa tcgaaccaaa ctttcaccat acacaagaga gaaactcgat
    24421 gagttaaccc aatatgtgtt aacaaaagaa cctggatatc aagaatatat acagatttca
    24481 aaagcattga aagaagaagc aaaaagtctt tatggggaaa gcaagagaga atcaaaggat
    24541 gcagaaaaaa atgctctctt tgatttaaaa aagcgcacag gaaatgccat tctaacagaa
    24601 ctgaagaaac aggatagtca aataaaacct ttaatagaaa ggatggatca gatgcaatct
    24661 atttacaatg aacgatcctt tcgaacactt aaacagttgc caacgaatga atacaaatat
    24721 agttacgaag aattcatgaa gcgcaggaaa caattccaac aaagagttgt cacgcaacgg
    24781 agtttgcgtc aattaaatcg aacgattaat gcccatgaag aaaaatacca cgcaagtaaa
    24841 gcatacgaag agcaacaacg aagaattcaa atggaacaag aaagacagta ggaggaatag
    24901 caatgaaaca atatttagat caatggaaag ttatagaagg atcattaaga gaagaacgaa
    24961 tcgaacaact tcccgattgt ttagaaaaag agcatttgtt tcagataaga gaaatgttga
    25021 taaacgaaca gtttgatcca aatcaatttt tagtcgttga gtacccagct actggtgtgt
    25081 actgttgtaa tcatgtgaag ggtgaaaaat attttatcat tcaagaatat gagggcaagt
    25141 tagcgcctta ttatactact tgggaaatga atgaagaggg gatcaataac ttcccgtgta
    25201 aaagcattga agagtctatt tcactcacag aatgttagtt gttaagtgaa taaaagaagt
    25261 aaaagagtcc tgaacgtgat tgtccaggac tctttttttt cactgaattg ttttccgcca
    25321 attcattgag tggtgcgatt tccgtctaca ttatatcaaa agaaaggagg aagaagaaat
    25381 ggcttattca acgattggag ttgttgttga aaaaagcaga gacaatcttg tttttgtgac
    25441 agaaattcaa acaggcagag cttttgtagt cacagacaaa gcggcaaaag catatcaaag
    25501 tggcgatatt ttaacgttaa atctgactac gaagacgttc gtcgatgcgg cagaagatta
    25561 tccatt
//
LOCUS       DAYYEF010000038        25500 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000038 DAYYEF010000000
VERSION     DAYYEF010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.039"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            131..3658
                     /locus_tag="ACHA1B_001811"
     CDS             131..3658
                     /locus_tag="ACHA1B_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HFM8702571.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3655..7377
                     /gene="addA"
                     /locus_tag="ACHA1B_001812"
     CDS             3655..7377
                     /gene="addA"
                     /locus_tag="ACHA1B_001812"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0016818 - hydrolase activity, acting on
                     acid anhydrides, in phosphorus-containing anhydrides
                     [Evidence IEA];
                     GO_process: GO:0000724 - double-strand break repair via
                     homologous recombination [Evidence IEA];
                     GO_process: GO:0006302 - double-strand break repair
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HFM8702572.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7446..7787
                     /locus_tag="ACHA1B_001813"
     CDS             7446..7787
                     /locus_tag="ACHA1B_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HFM8702573.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8096..9139
                     /gene="pheS"
                     /locus_tag="ACHA1B_001814"
     CDS             8096..9139
                     /gene="pheS"
                     /locus_tag="ACHA1B_001814"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HFM8702574.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9144..11564
                     /gene="pheT"
                     /locus_tag="ACHA1B_001815"
     CDS             9144..11564
                     /gene="pheT"
                     /locus_tag="ACHA1B_001815"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004826 - phenylalanine-tRNA ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006432 - phenylalanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HFM8702575.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="ACHA1B_001816"
     CDS             complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="ACHA1B_001816"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004830 - tryptophan-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006436 - tryptophanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HFM8702576.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12998..13735
                     /locus_tag="ACHA1B_001817"
     CDS             12998..13735
                     /locus_tag="ACHA1B_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFM8702577.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13749..14564
                     /locus_tag="ACHA1B_001818"
     CDS             13749..14564
                     /locus_tag="ACHA1B_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HFM8702578.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14577..15224
                     /locus_tag="ACHA1B_001819"
     CDS             14577..15224
                     /locus_tag="ACHA1B_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFM8702579.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15240..15896
                     /locus_tag="ACHA1B_001820"
     CDS             15240..15896
                     /locus_tag="ACHA1B_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HFM8702580.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16058..16879
                     /gene="racE"
                     /locus_tag="ACHA1B_001821"
     CDS             16058..16879
                     /gene="racE"
                     /locus_tag="ACHA1B_001821"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008881 - glutamate racemase activity
                     [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HFM8702581.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16882..18237
                     /gene="rph"
                     /locus_tag="ACHA1B_001822"
     CDS             16882..18237
                     /gene="rph"
                     /locus_tag="ACHA1B_001822"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000049 - tRNA binding [Evidence IEA];
                     GO_function: GO:0009022 - tRNA nucleotidyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HFM8702582.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18238..18756
                     /locus_tag="ACHA1B_001823"
     CDS             18238..18756
                     /locus_tag="ACHA1B_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HFM8702583.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18863..19363
                     /gene="cbpB"
                     /locus_tag="ACHA1B_001824"
     CDS             18863..19363
                     /gene="cbpB"
                     /locus_tag="ACHA1B_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0180001 - cyclic-di-AMP binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP-binding protein CbpB"
                     /protein_id="HFM8702584.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19643..20563)
                     /locus_tag="ACHA1B_001825"
     CDS             complement(19643..20563)
                     /locus_tag="ACHA1B_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HFM8702585.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20689..21741
                     /locus_tag="ACHA1B_001826"
     CDS             20689..21741
                     /locus_tag="ACHA1B_001826"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004084 - branched-chain-amino-acid
                     transaminase activity [Evidence IEA];
                     GO_process: GO:0009081 - branched-chain amino acid
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HFM8702586.1"
                     /translation="MIKCGENNEGGKYMQIDWNNLGFSYIKTPWRFIAKWKDGQWEEG
                     ELTEDNYLTIHEGSPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLM
                     PMVPEKMFVDAVKQVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVF
                     CTPVGAYFKGGLKPTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCV
                     YLDPATHTKIEEVGAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIE
                     GDIFIDDLDQFAEAGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGI
                     QFGDIEAPEGWIEVVE"
     gene            complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="ACHA1B_001827"
     CDS             complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="ACHA1B_001827"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HFM8702587.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22826..23266
                     /gene="fabZ"
                     /locus_tag="ACHA1B_001828"
     CDS             22826..23266
                     /gene="fabZ"
                     /locus_tag="ACHA1B_001828"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HFM8702588.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23381..24142)
                     /locus_tag="ACHA1B_001829"
     CDS             complement(23381..24142)
                     /locus_tag="ACHA1B_001829"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFM8702589.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24331..25425
                     /locus_tag="ACHA1B_001830"
     CDS             24331..25425
                     /locus_tag="ACHA1B_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HFM8702590.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8448 a         4424 c         5384 g         7244 t
ORIGIN      
        1 tttgcgtata cttaaaaaag tagaaatatc agaaccttaa aaggatataa tttgaagaat
       61 atagaacaaa tgttcagtat tttttgatat aataaaggag caccgtatca tgtgttgaag
      121 gaggaaaagc atgtctttac aatttattct tggaaacggg aaaaaagatc accgtcaagt
      181 cttgatcgac gaagcatccg cttggctcga ccaggatgca agtaaccaag tatttttcct
      241 tgttcccaac tacagcaaat tcgaacagga acaagaaatt ttagcggaga tgcgaagaag
      301 aagcggaaaa aaaactttca gcacaacaaa cgttcaagta tttagttttt atcgtctggc
      361 ttggtatttg ctgcaacaga caactcttct tacaggaaat gaattatcag aatcaggatc
      421 tgcaatgatc ttgcgacaga ttttagaaaa aaatgaggaa gaattaacaa tctttcgcgg
      481 agaaatcaat aaaagagggt ttattcgtca attacaagaa ctctacagtg aattgcgtac
      541 aggaaatatt caaccagaag acctgatgct tttatttggt gattcaccta atgcagaaga
      601 ccagcaactt aaaatgaaag acttgaagct gattttttca gcttatgaca gcgaattgac
      661 tcaacgtgca ctaacaaatg aagatgcact atctatacta gcaaattata tgcagacaca
      721 agatttcaac aacgtcaaat ttattgtcag tggtttttct cgaatcaatg gtcaagagta
      781 tcaattactg caggcaatga tggaaaaggg gcaattggtt gtcgatttat tgctggatcg
      841 tccttataca gcggatcttc cagaagtact tacgctcttt catgagactg gaaagcttta
      901 tttccgtctt tttcaaagtg caagagaacg gaaagtccct atattagtgg accgatttgc
      961 accagagcag actcgtccga cagagcttca actgctgcaa acaatgtggg aagagacatc
     1021 tagccaaaag aaagcggcag tacacaaaat agggggacaa gagcatctcc atttgtggga
     1081 agctgaaaat ccaactgaag aagtccgaca attagctgtt gaaatcagac gactagtcag
     1141 tgaagaaaac taccgttatc gtgatatcca agtgctgaca aaaaatatgt ctttatatgg
     1201 aaatatcctt cggccgatct ttcaagaaat ggcaattcct ttttatatcg atgaagaaca
     1261 aatgatggaa aatcatccgc tgatcgaatg gatcaacagt ctgttcgctc ttgaccgcta
     1321 ttcttatcgg ctaagtgata ttatgcgttt tttcaaaact gaattatttc tgtcgacgga
     1381 agcagaaacc gaacttgatg aatggaaaca agagcgagat gaattcagga aaaaactgga
     1441 catcactgaa aatgtagcac ttgcttacaa ttatcaagga acttattgga ctcgtgaaaa
     1501 agactggcag tttgtggcgt atgattttga agcagaacag attgaagacg tacagtattt
     1561 ggaagaacag tcaaatacga ttagacgatt atttcagaaa gctgtaccag tatttttgaa
     1621 aaaaataaag aaaagcaaaa caggacaaga ggccgcaaat gttttttatc aatttttgat
     1681 ccaaagtggc gtacagcaac aattattgtt ttggcgtaat caggaagtag acagaggaaa
     1741 cttagaagcg gcaagaaacc atgagcagac atggggagcg ctgattgatc tgttggatga
     1801 atatgtagta atttatggtg aatcggcttt tgactggtca ctgttccaag aaatcattac
     1861 aagtggtcta gaaaatctaa gttatggtaa aatccctacc gcaatcgacc aagtgcgaat
     1921 caatcgtttg gaattagttc gaccaaatca agctgccgtc acttttgcat tagggttgaa
     1981 tgatcaagtg tttccagacc gaaaagagac aaaaggattg ttgtccagtg aagaacgaga
     2041 agtattaaat caggccttgc cagatggaca gtttttattc gacccatcaa aggaaagtat
     2101 ctcttttgag cctttccaag cctatcttgt ttttctttcc ggaacagatc gattatatct
     2161 tagttatgca caaagctatg acacagatgg ttcgctgaag atgtctcctt atttgcgtag
     2221 aatcacagaa tatttatctg ttcccgtcga gagaaaagag catttgacga tcgaaagcga
     2281 ccctaattgt tatgtaggga cttacagaag cggaatcaat acagtcaata ggatttatcg
     2341 attagcttta gatgaaaaaa aacctgtacc aaagcactgg caaaagctca aagaattagt
     2401 actgaattcg tcatggcgaa attttgcttt acagattttt gaaagtcagg aacatttaaa
     2461 tgttcctgtt tcgatgccag aaaaaatggc ggaagagctt tatggaaaag agatttatac
     2521 ttcaatttca cgtatggaga atttttataa ttgtgaatac aaatacttca tgcaatttgg
     2581 tttgaaattg aaagaacgaa ctgtttatgg tctaactcca gcagcaactg gtgattttta
     2641 tcatgaatca ttggatcgtt tcttcaagct actgttttca aaccaattat ccttagtgaa
     2701 tatgtccgat gcgcagcgta gagactttac tgaaaaagtg ctgcaggaag tattcggaga
     2761 acttcggttt gagatattgg atagttctgc aagaatgaac tatatccgct accagttagg
     2821 acagacgatt caaaaagtga catgggcttt gcaaaaacag agcaaaaata caggcatgca
     2881 tcctcttcag acagagattc tatttggtca gattgctgga gcaaaaggta tcacaggtct
     2941 ggaattaccg ttgagtaatg gtggaaaact ccatgttcga gggaaaatcg atcgaatcga
     3001 tgtagcttct gaacaagaag atacttggct aagcgtcgtt gattacaaat ctagcggacg
     3061 ttcattcgat gtcacagaag cttattatgg catggctatg caattattga cgtatctgga
     3121 cgtagcattg atggatgcgg tacgtttgac tggaaaggcg gctgttaaac cagcaggatc
     3181 atattattta catgttcata atcctgtatt gacggagaca gatgatgtag agaagaatac
     3241 attgaaaaaa tttagttatg atggcgtttt tgtcgatgat cccgctcttt tagaagtact
     3301 agatcattca ctggaagcaa aagaacaatc actgatctat ccagtgaaaa aaaatgcgaa
     3361 agatgaatac caaaaaggta gtttcagtaa agacaaattt ttcacggaag aagaactgca
     3421 actattcatg gcgcataatc gggaaaatat gcggttagct ggagatgcga ttacttccgg
     3481 agaaatcaaa ctaaatccag cttataaaga taaacagcgg attgcctgcg aattttgtcc
     3541 attcagaagc atctgtacgt ttgatgtgat gctgaaagaa aataattacc accgtctgga
     3601 gaaaatagat aaggaagaag cactgcgtag aatattgaaa aggagtgaag aagagtgaat
     3661 caaattcctt taaaaccgca aaatgaacga ttcacagatg atcagtggca agcgattttt
     3721 gatcaaggag ataatctatt agtctctgcg tctgccggat caggtaaaac tacagtgctt
     3781 gttcgaagag tgattgaaaa actaaaaatg ggttttgata tcgatgaatt attgattgtg
     3841 acatttactg aagctgccgc aagagaaatg aaagaaagaa ttcaagaggc attacaagaa
     3901 tccgtcaata gcgaaagtga ccctgtacgt agacagcatt ttactaagca gttagtttta
     3961 ttgcccacag cgaatatctc aaccttacat gctttttgcc tgacagttat tcgacgttat
     4021 tattacttaa ttgatattga tccagtcttt cgcatgttaa cagatgaaac agaaacgatc
     4081 ttgatgaagg aggatgtgtg ggacgagctg agagaagcac tttatgcaga aaatgatgaa
     4141 cgatttttcc aattaacaat gaatttttct aatgatcgtt cagatgacgg cttgacgaat
     4201 ctggtgtttt ctctttatga gtttgcccgt gccaaccctg acccccaaaa atggctagaa
     4261 cagttaagcg ataattatcg tttgcctgag gggctagcga aatctcgatt atatcaaaaa
     4321 caaatccgtc ctttagtttt ggcagatata taccaatgtg tacagttata tgaacagatg
     4381 actcagttag cacaaggtga aggattagaa aaaatgcatg agcaagtagc tggagaacaa
     4441 cagcagatca agaatatcta tgaagcgttc tcgcaagatc ggttagaaga agcttatgct
     4501 ggtttggaac aactaacttt ttcaactttt aagagcagtc ggaaagcaga attgaaagaa
     4561 atttccaatg aagtcaaggg catgagggat aaagcaaaaa aactgattca gcagataagt
     4621 aaaagttatt ttcctgtttc cccaagccaa atggaagaat taacggacaa agcactaccg
     4681 ttagtcgaag aaatgacaaa agtcacgcaa agcttcatgg acggtttcag tatgcgtaaa
     4741 cgggaaaaag gtgtgctgga tttcaatgat ctggaacatt tagcgttgca gattctcaca
     4801 gaaaaaacga aagatgtatg gctgccaagt gaagcttcaa aacattatcg aaaaaaattc
     4861 aaagaagtaa tggtagatga atatcaagac gtgaaccaat tacaagaagc cattttatac
     4921 tggctaagag aacccgatga tacaaaagga aatatgttca tggttgggga tgtcaaacaa
     4981 tccatctatt ctttccgttt agcagatcct agtttattta tcgggaaata cgagaatttc
     5041 tcaaagaaag aaggcggacg tcgaatcgtt ttggctgaga acttccgctc tagaaaagaa
     5101 gtcctttctt ttacgaatct tatttttgaa caactaatgg atccagcagt gggtcaaatc
     5161 aattatgacg aagcagccaa actgatccaa ggattttcag actttccaga gaatgaacag
     5221 tttgagccgg aaatcatgat ctatgaaaaa gaacaggaag aatcagagat tgagattccg
     5281 acggatgata tactggaaga caaaacagaa ggcgaacttt ttatgacagg actaaaaatt
     5341 cgtcaattaa ttgattcctc ctttatgatt tatgataaaa aatcaaaaaa aagtcgtccg
     5401 atagagtaca aagacattgt tctcttgaca cctacaaaga agaacaactt aacgatttta
     5461 gagattttca aaacattgga tattccatta gagatgaatg atgctcaaaa ctattttcaa
     5521 gcgacagaaa ttcgcacgat gatctcgctg ctacaattaa tcgataatcc ctatcaagat
     5581 attccgcttg cggctgtatt gcgctcaccg atcgtgggtc tgattgaacc agaattagcc
     5641 agcattcgat tagctaaccg tgcacatact tactatgatg ctgtgcttgc ttatcaagca
     5701 tcaaacgaag atgaattagc agctaagctg gaacattttg gcaagcaact agagcattgg
     5761 cgagaacttg ctcgccgttc ttcgatcact gacttgttat gggatatcta ttatgagacg
     5821 ggatatctag agtatgtggt cggtctgcca gcaggggcac agagacaagc caatctttat
     5881 gcattggttg atcgtgccaa agcttacgag caaagttctt tcagaggatt ataccagttc
     5941 gtgcgtttca ttgaaaaaat gcaagaaaaa gataaagact tagcagaacc agtcatttca
     6001 atagaagata atgctgttcg cgttatgacg atccatgcaa gtaaaggctt ggaattccca
     6061 gttgtatttt tgttagatat gacaaaggag ttcaacttac aagacttgcg caatcggtat
     6121 gcttttgaag aaaaacttgg agcaggaatt cgctatatgg atcctgaaac acgagtgtta
     6181 tatgatacgt taccgtttca agccatcaaa ttggcaaagc aaaacaaatt gttgtcggaa
     6241 gaaatgcgta aattgtatgt aggattgact cgggcagaac aaaagctttt cattgtcggt
     6301 tcctataaaa ataaagagca aatgatccaa acgtggtctg aagcagctga tcatgaggag
     6361 ttagtttttg atcctgcgct acgtttgaag ggcagaagca gcttgatgaa ttggattggt
     6421 tacggattga tccgtcatcc tgaaatgcag aaatacttag aggaagaaat ttcgacttct
     6481 cttcttcaac attcaaatgc acagttttct atttcatgga tgaatcagca atcgatcatt
     6541 gaacaaagac agttgcttgc tgaaaaagaa ctggttaact tagatcagca gatgaaagaa
     6601 gatgaaactt tattagcaga ttcgttacaa aaacgtctgg catatgaata tccttatcaa
     6661 gcttcttcac aaaccacaag ttatcaatct gtatctgaaa tcaaacgatt attcgaagat
     6721 ccagatgata cacaagaatc acgtttgact ctggaaagca gtcagaacaa agcagcatcc
     6781 cgtcaatttc gttatacgca agaacaacta gcagaaccaa aatttttgca aaaagatcgg
     6841 caagtgtcag cagctgctgt tggaactgct acgcatgctt tgttacaatt actgccatta
     6901 gagatgccaa ctacagagag tatccatcaa aaattacagg aattggtaag gaaacggtta
     6961 gtagacgaaa aagtcgcgaa aaaagtagat gtttcttcta ttatatggtt ctttcaaaca
     7021 gaacttggtc aacagctgat tgccaacaaa gaaaacgtaa aacgagaaca acctttttcc
     7081 atgctgcttc ctgctgacga agtatttcaa gactatccaa atcaagaaga tgaactatta
     7141 atccacggaa tcgtcgatgg atacctagaa gaaaaagatc atctcaatat ctatgatttt
     7201 aaaacagatt ttattttaca tccggatgat ccagcagaaa tagatgcaat cgtccaaaaa
     7261 tatcaaggac agctaagact ttaccaacaa gcaatgtcag aagctttgaa taagccagta
     7321 gaaaatgttt tcctaatttt gcttcgagtg aaacaaatta taaacattaa caaataatta
     7381 taattgagca aacttgactt atgttttgta aggattatgc tatactctgg gaagaggtga
     7441 gtatgatgga gctaacacag acagaattcg ttttatgccc taaatttgaa aaaacattct
     7501 ctattttagg aaaaaaatgg aacggattga ttatcgatgt actactcgaa aacggtccgc
     7561 aacgctttgt tgagcttgcg gcaaaaatcc cgatggtcag tgatcgagta ttagtcgaac
     7621 gcttgaagga attagaaaaa gaaggaatag tcactcgaaa ctttgcctgt agcgaaaaga
     7681 gccgttcaga atatctcttg actgaaaaag gagcagactt gcaaaaagcg atgcgtcaaa
     7741 tacaagtttg gagcgaaaaa tggatcacag aggaagaatg cggttgattt tgtaaaaaaa
     7801 atcttgtaaa ctatagtcca tacgaataag taaagaacga tgacgaaaaa gagtagtttg
     7861 gctaaaccag ttcagggaga tctgtcgcag actgaaagca gatcctgtgt ttgaaaaatg
     7921 aagttcactt tccgagttcg tctgataaaa tcagaccggc aattgtcgtt aacgaagtaa
     7981 gagtgcggtg taagtcattt atccgcaaat taggatggta acgcgaagac ctcgttcctt
     8041 aacaggaatg aggtcttttt gttttgtatt tggaatttaa aggaggaaca agcacatgtc
     8101 tctacaagca caattagaga gcttgaaaga agcaacgctc gtcaaaatca cagcggcaca
     8161 agatttaaat gaattaaatc aaatacgtgt tgaaacgtta ggaaaaaaag gaccgatcac
     8221 agaagtatta cgtgggatga aagatctaag tccagaagag cgaccaaaag tcggaagttt
     8281 cgcaaatgag atccgagatc ttttgacaga agagatcgag cgaaaaaaac aagtattaga
     8341 agaagaagcg ttaaatgcag ctttggcaaa agaaacaata gacgtgacac tacctggtag
     8401 aaaagtaaaa catggtacac gtcatatcgt gacacaaatc atggaagaaa ttgaagatat
     8461 ttttgtgggt atgggctatc agatcgtaga aggatatgaa gtagaatctg atcattacaa
     8521 tttcgaacgg atgaatctgc caaaagatca tccagcaagg gacatgcaag atactttcta
     8581 tatttcagac gagatattga ttcggacaca tacttcacca gtccaagcac ggacaatgga
     8641 aaaacatgat ttctctaagg gtgctctacg aatgatctcg ccagggaaag tcttccgcag
     8701 agatacagat gatgcgaccc acagtcatca gttccatcaa attgaagggc tagttgttga
     8761 taaaaacatc acaatgggcg accttaaagg aacattagaa gtcgtaatga aaaaaatgtt
     8821 tggggaagat cgtgaaattc gtttgcgtcc aagttatttc ccatttacgg aaccatcagt
     8881 agaagtagat gtcagctgtt tcaaatgtgg tggtgccggt tgtaacgtat gtaaatacac
     8941 tggatggatc gaaattttag gagctggcat ggtacacccg aatgtgttga agatgtcagg
     9001 aatcgatcca gaagaatatt caggctttgc tttcggcctt ggaccagacc gcgtagctat
     9061 gttgcggtat ggagtgaatg atatccgtaa tttctatcaa aatgacttac gtttcttaag
     9121 tcagttcaag ggggagtaag aaaatgttag tttcatataa atggctcaat cgttatgtag
     9181 atttatcgaa tgtaacacca aaagaattag cggataagat gtctgtgaca ggaatcgaag
     9241 tagagggagt aacggttcca gaagaaggct tgaaaaaaat cgttgtcggt gaagtcaagg
     9301 aatgcgtacc acatccagat tctgatcacc tttctatttg tcaagtcgat attggcgaag
     9361 acgaactgtc tcaaatcgtt tgtggagcgc ctaatgtgaa ggttggaatc aaagtgattg
     9421 ttgcacttcc taactcacgt atcgctggta atgtaaaaat caaaaaagga aaaatgcgtg
     9481 gccaagtatc aaatggcatg atttgctcat tacaagaaat tggctattca gatagtgtta
     9541 taccgaaaga atacgctgaa ggtatctatt atatgccaca agaagctgta aatggcgatc
     9601 cagtttttcc ttatttggat atggatgatt cgattattga attatctatc acaccgaatc
     9661 gtgcggatgc attgtcaatg cgtggcgtag cttatgaagt tggggcaatt tatcgtcaga
     9721 ctcctacatt cgatgacgaa aagctggtag aatcctcacg tcctgctagc gataaaattc
     9781 aagtggaagt tgaagataaa gaagcagttc ctgcttatca aatcagaatc attgaaggag
     9841 taagaatcca gccaagtcct caatggctgc aaaatctttt gatgaacgaa ggcattcgtc
     9901 caatcaacaa tgtagtagat gtgacgaact atattttgct tttattcgga caaccactac
     9961 atgcatttga ctacgacaaa ttgaaatcaa aagagatctt tgtccgccgt gcaaaagaaa
    10021 atgaaacatt agtaacacta gatggagaat ctcgggaatt gacaactgac aatctcgtca
    10081 ttactaacgg caaagaacca gttgctttag ctggtgtcat gggagggtta gactcagaga
    10141 tcacgaatga aacaacaaca gttgcactag aatctgcttt atttgatcca atttcgattc
    10201 gtcgtacagc aaaacaattt aatttgcgta gtgaatcctc tgcacgtttt gaaaaaggaa
    10261 tcaaccatgc gactgttgga gaagccagtg aggttgctgc agcaatgatc gtttctcttg
    10321 cgggtgggga agttctacaa ggcgcggtca aaggctcaga gatcaaagca gaagacgtat
    10381 cagtgaagat ttcacttgaa cgcatcaatc aatatttagg aacatctctt gtcgttaaag
    10441 aagtaaatga gatttttgaa gcacttggat ttagctatga agaaaaggag tatgtttatt
    10501 ccgtagtagt accaccaaga cgctgggata tccaaatcga agcagatatt atcgaagaag
    10561 ttgctcgtat ttatggatac gaccagttgc catctacact tccaagtgga gaaacggttg
    10621 ctggaagctt gtcaaaagaa caagaaacta ctcgtaaaat tcgtacaatc tttgaaggaa
    10681 gcggattgag cgaagcaatc agttatgcat tgacaacaga agaaaaatca agacagtttg
    10741 ttataaatga aagtaatatt acacgtttgg actggccaat gagcgaagaa cgttctgtat
    10801 tacgaatgaa tttgatcagc ggactattag atgatatcag ttataacact gcccgaaaaa
    10861 atacagagat tgctttatat gaaattggtc gggtgttctt ccaagaaaat gatccacgta
    10921 cacatctgcc gcaagaagta aaacatgcag caatcgctat ttctggtatt tgggaagaaa
    10981 aagattggca gacgaaagct caaaatgtag actttttcac catcaagggt cttttagaaa
    11041 acttatttga acaactaggc atcactgaag atgtccatta tcaaacagtg acagaaatga
    11101 aggaaatgca tcctggaaga actgctgcga tttaccttgg cgaaaaattt attggttttg
    11161 tcggtcaagt gcatccaacg attacaaaaa gttatgatat tccagaaaca tatgttgctg
    11221 agtttgattt atctgctata gtggaagctg ctcaaaaagg gatcgttttc gaagcagtga
    11281 caaaattccc agcagtcagc cgggacatcg ctttgcttgt aaaagaaact gtgacaaatc
    11341 aggaattaac agaagttatc cgttctgctg ccggaagatt tttaacagat atccaattat
    11401 ttgatgtcta tcaaggagaa aacattgaaa aaggacataa atccatggcg tatagcctga
    11461 cattcgtcaa cccagaagca acattgacag atgaagaaat caataaagca atggaaaaag
    11521 tcgaaaaagc gttggtagaa aacctagagg caagtattcg ctaagaagga aaatatagta
    11581 agtaacgatc aagtagcttt tgaagaccat acatttgaaa aaaagatgtg acacaacttc
    11641 gtcacatctc tttttttgat tttaaaaaag gaatagcaca gagacgagat aaaaaaacag
    11701 gcctttacag cctgcttttt tagagtaaat gaattaatgg aagtaattga ttcccattgc
    11761 tgattttact tcagaaagtg tttgtgcagc tactttagca gcttcttcac tacctttacg
    11821 taagatttcc ataacagctg aaggatcttt ttccaattct tctcggcgcg cacggatcgg
    11881 tgcaaattca gcttccaata catcaatgag gtatcgtttg atctttacat caccaagtcc
    11941 gccgcggcgg taatgagctt tcatttcttc aattgcttct ttatctgttc cgaatacatc
    12001 caagtaggtg aagaccatat tcccttctac ttgtccagga tcttgtacat ggatgtggtt
    12061 tggatcagta tacatactca tgactttttt ctgtaagaca tcggcaggat cggagatata
    12121 aataccgttt cctaacgatt tactcatttt gccatttcca tcgattccag gtaatctacc
    12181 cattcctttt ggtgggaata cgccttttgg ttccaccaag acttcaccat atgtatgatt
    12241 gaagctttgt acgatttcct gtgtctgctc tagcattggt ttttgatcct caccaacagg
    12301 tacaagattc gctttgaatg cagtgatatc tgctgcttga gaaacaggat agataaagaa
    12361 tcctgtaggc acgctttcac cgaatttttt ttgttcgatt tctgttttga cagtcggatt
    12421 gcgccgaacg cgtcctacgc tgactaagtt caaataatac atggttaatt cagctaattc
    12481 cggaatttgt gattggataa ataaagtaga ttttgcagga tctaatccca cggctaaata
    12541 gtctaaagca acttgcaaga catttgatga aaccttctca ggatttttag cattatctgt
    12601 cagtgcttgc atgtcagcaa tcatgacaaa cagttggttg tcttcatctg cctgcatagc
    12661 cactcgggtt tttagagaac cgacgtaatg ccctaaatgc agcttcccag ttggtcgatc
    12721 tcccgttaaa ataatatttt tcaaaaaaga cacctcttta cgatttgtaa gtctgagcac
    12781 ttaatatctt accgtttttc ctgaaaagaa acaacagttc ctaaggaaaa aacaaggaaa
    12841 gaggataaaa taactaatag attagaaatg gaagaaatat ttatgggaga ataaacgttc
    12901 taagaaactt tacaaattac taaactatca gatataatgt attttattat acatctttaa
    12961 aagaaatctt actaaataat aatgggagtg taattctatg gcaatgatta aatttgatca
    13021 cgtggataaa tattatggca agttccacgc attaaaaaat atcaatctcg aattcgagaa
    13081 aggagaagtt gtcgttgtca ttggtccttc tggttcagga aagagcacga tgcttcgctg
    13141 tatcaatgga ttagagacga tctcttcagg taagctgctg attaatgata ctgacttgca
    13201 tgataaaaag acaaaactga cagaagtccg aaaaaacatc ggcatggttt tccaacattt
    13261 caatttgtac ccaaataaaa ctgttctgga aaacatcaaa ttagcaccaa tcaaagtgtt
    13321 gaagcaagac caggcaactg cagtcaaaaa cgcggagaaa tttttgaaaa ctgtcaatat
    13381 gttagataag aaagattctt atccttccat gttatccggg ggacaacagc aacgggtggc
    13441 aatcgccaga ggtttagcga tgaatcctga gatgctgctg tttgatgaac ctacttctgc
    13501 tttggatccg gaaatgattg gtgatgtatt agacgttatg aaaaaattgg ctcatgacgg
    13561 tatgtcaatg attgtcgtga cacatgaaat gggctttgcc aaagaagtgg cggatcgtgt
    13621 tatcttcatg gctgatggag aagtattgga agacagcaga aatgtgagag actttttcga
    13681 aaatccaaat gaagtccgag cacagcaatt tatcagtaaa gttatcaatc attgatagga
    13741 ggaaaaagat gcgcaggtta aaaaaaatac gcctgatttt ccttttaggc attgcttttc
    13801 ttgcactagc cggatgtaaa ggaaatgggt tggcaaatga agatatttta gagcgaagca
    13861 aatctaccaa tgaaatcatc tggggtgtca agtatgatac tcgattattt ggaatgatgg
    13921 atattgagag cagaactgta caaggatttg atgtagatat tgcaaaagca atcactaaaa
    13981 agatccttgg tgacaatgga aaaacagaat ttgttgaagt cacttctaaa actcggattc
    14041 cattattgaa aaacggaaat atcgatgcaa ttattgcaac gatgacgatc acagatgaac
    14101 gaaaaaaaca ggttgacttt tcagatgtct atttcgatgc tggccaagct ttgttggtaa
    14161 agaaaggaag ccaaatcaaa agtgtagatg atttgaatgc ttctacaacg gttctagcag
    14221 tcaaaggttc tacatcggct gcgaatatcc gacagcatgc accagatgca aaaattttag
    14281 aattagaaaa ctatgcagaa gcatttactg ctttacaatc tggtcaggga gacgcgatga
    14341 ctacggataa tgcgattttg ttagggattg cagatgaaaa tccagagtat gagttagttg
    14401 gtggaacgtt tactaatgag ccttacggga ttgcgatcaa caaagggcaa gaaaacttct
    14461 tgaaagctgt taaccaagcg ctagaggaaa tgcatgcaga tggcacatac gataaaatct
    14521 atcaaaaatg gtttccaaat gaaactgaag gaaaagtaga gtaaggggga gaggcaatga
    14581 gcgaattgat acaaacttat ggaccaatct ttgtcgacgg gttcaagatc acattgtttt
    14641 cgagtgtctt agcacttgtg tttagtttga ttatcggaac gttaatggca atcttccaat
    14701 tatcaaagaa taaagtagtg agcgccttag caaaggcata tgtagaattt tttagaaaca
    14761 ttccattatt aatcatcgtg atgttttttt atgttgtcgt accgatttat tggtttaatc
    14821 tagatggatt ccaagcaggt acgattggat taacgatcta tacatctgct tttattgctg
    14881 aaacagtacg ttcagggatt caaaccgtac caaaaggtca aacagaagca ggactatctt
    14941 ctggttttac ctattcagaa atcatgcgtt atattgtttt accgcaagca ttcaaaatcg
    15001 ttatcccgcc attaggcaac caatttatca acctcgtaaa aaactcatct attttagcaa
    15061 tcgtagctgg tttagatttg atgtatcaag gagacttgat cgctagtgaa acattcaata
    15121 ccttcgatac gtatatcatc gttgggttat tttacttagt tatcacgcta ccgttatctt
    15181 acttaatggt ttatcttgag aaaaaatggg cggttcgttc atagaaggag gggaaataca
    15241 tggattttag cggcgctttt tcatggatga atatccgttt tttattggaa ggattaaagg
    15301 ttactgttga agtttcattg ttttcgatca tttttagttt cttgatcggt ggtctgacag
    15361 gtgtgattcg ttttgcgaat atccctttct tttccaaaat ccttggtgta gtgattgata
    15421 ttatacggaa tcttccatta ttattgatca ttttcttcac ttactttgcc ttacctcaaa
    15481 tcggcattca gatgaacatc ttctggtccg ctgtcgcagc attaacgatt tttgagtcag
    15541 ctatgttgtc ggaaattttc cgagctggac tcaatgctgt tccaaaagga cagatggaag
    15601 caggattatc aacgggactg acttatgtag aatcgatgcg aacgatcgtg ttaccgcaag
    15661 catttaaatc aatgatcccg gcaattgtga gccaattgat ttcactgatc aaagatactt
    15721 cattagcagt aatcatttct ttacctgaac tttctcatca ggcacgtatt atttatggac
    15781 agaacaccaa ttatgtgctt ccgatgttca tcatcatgac acttatgtac ttcgtggtat
    15841 gttacgcgct ttctctgctt tccggttact tggaaaagag acggtacagt tattaataga
    15901 tgattctttt agcggttgtg gcaaactaaa gtcacaaccg cttttcctct ttccattcga
    15961 aaaaaagaga tttcgattgt tttaagcaag taagagcact tgaaaattca cgctaaaaag
    16021 tacacaatag ggaggataga atttattgaa aaaaaggatg atacgattga cagataatcg
    16081 ccctatcgga tttattgatt caggtgtcgg cggcttgact gtagtaaaag aagccctgaa
    16141 acaattaccg aatgaaaata ttttatttgt aggagacaca gcacgctgcc catatggccc
    16201 tagacccgcg gaacaggtaa tccagtatac ttgggaaatg acggattatc tggtggagca
    16261 aggaatcaag atgctggtga tcgcctgcaa taccgcaact gcggtggctt tagaagaaat
    16321 caaagctgct ctttctattc cagtcatcgg tgtgatcctt cccggtacta gagcggcagt
    16381 aaaaaaaaca caaaataaac aagttggcat tatcggtacg attggtacgg taaaaagtca
    16441 agcttatgaa aaagcactga aagagaaagt accagaattg actgtgacaa gtcttgcttg
    16501 tcccaaattt gtttcagttg tcgaaagtaa tgaataccat tcatcggtgg cgaaaaaaat
    16561 tgtggcagaa acattagctc ctttaaccac taaaaaaatc gatacattga ttttgggatg
    16621 cacccattat ccattattac gccccatcat tcaaaatgta atgggagaaa atgttcaact
    16681 gatcgattct ggagcagaaa cagtaggtga agtatctatg ctgttagatt atttcaattt
    16741 gagcaattca ccgcaaaatg gtcggacatt atgccagttt tatacaactg gctctgccaa
    16801 acttttcgag gaaatagctg aagactggct tggaatcgga cacttaaatg tagaacatat
    16861 cgaattggga ggaaaataag gatgcgtcat gacgggagaa aagcccaaga gcttcgcaaa
    16921 ctggagcttc aaacaaatgt tttcaaatat ccagaaggat cggtagtgat ccgttttggt
    16981 gatacaacag ttatttgttc tgcaacaata gaaaattctg ttcccccttt tttgagagaa
    17041 acaggaacag gatgggtgac agcagaatat agtatgctgc ctcgagcaac gagtacgaga
    17101 aatcgtagag aaagcagcaa agggaaactt tctggtagaa caatggaaat ccagcgtctt
    17161 attggtcgtt ccttgcgtgc agtagtagac ttggaaaaat taggagaacg tagtatcatc
    17221 gtagactgcg atgtgatcca agcggatggc ggtactagaa cagcaagtat cactggggca
    17281 tttgtggcat tgaaattagc cattgaaaaa cttttaagag aaaaagaatt gtcagaagat
    17341 ccaataaaag aacatcttgc tgcagttagc gtaggaatct taccagatgg gacttgcgtc
    17401 acagatttgg attaccaaga agattccgca gcacttgtag acatgaatct tgtaatgaca
    17461 gaatctggaa aattcgtgga gattcaagga actggagaag aagcaacgtt tgatggtgaa
    17521 cagttgaatg aaatgctctt ttttggaaaa aacgcgattg aagatttgat caaagagcaa
    17581 aaacatgctt tgctaacaga gtttgctcaa aatgatgagc ggatagaaga aacaaaaaca
    17641 atcatcattg cgacaagaaa tccaggaaaa gcagaagagt ttcgaaatat gttcaaagaa
    17701 gcgggatatc atgtaaaaac attacttgac tatcctgaat tgccagatgt ggaagaaact
    17761 ggcagcacat ttgaagaaaa tgcccgatta aaagcagaaa cgattgcaca attgcttgat
    17821 cagccagtct tagcagatga ttcaggtttg aaagtggatg ctttaggcgg tatgccagga
    17881 atctattctg cacgttttgc aggggaacaa aaaagtgatg cggggaataa cgccaaatta
    17941 ttatatgaat tgacagatgt gccggatgaa aaaagaacag cacaattcca ttgtacgtta
    18001 gtattcgcgg cacccaaaaa agacagcctt gtagtagaag cggaatggcc cggtcgagta
    18061 gcccgtatac catctggcga aaatggcttt gggtatgatc ctttatttat cccagaaggt
    18121 aagaaacaaa cagcagcaga attatcgagc gaagaaaaaa acaagatcag tcatcgggct
    18181 caagcaatga aaaaattgag tgccgagtgg aaacaatggc tggaaggaga gagatagatg
    18241 cggtatttag tagtaagtga taatcatgga gacagagata tcctcgttga cttagtagat
    18301 cgttatcgtt ctgaagtgga tatctttttc cattgtggtg attcggaatt agaagcttct
    18361 gacccattat gggatacatt ccaagtggtt caaggtaatt gtgattatgg accaggattc
    18421 gaacagaaaa aagtgatcca aactggtcag gatacagtat tcatgactca cggtcattta
    18481 tcgaatgtcc gatttggttt gacacagtta gcaatcgaag ctcgagctgc aactgccgat
    18541 atggtgtttt ttggtcatac ccatcaaata ggctgtgaga tggatcagaa aatcctgttt
    18601 ttgaatcctg gtagcatttc tcagcctaga ggcccgatcc aaatcccatc atatgctctt
    18661 atcgaaagtt tagatgacca aatttctgtt caatactata accgtgccca tcaggcagtt
    18721 gaagagttgg ccttttcttt ttcgagagag cgctgaataa aaaaactcta atttttaata
    18781 aaaataagct ttattttatg aattttgcat ccggtttcgg taaaatagta gtgttgaatg
    18841 aaatagaaat ggaggccatc agatgattgg acctatagta agagaaatgc tgctggaaaa
    18901 tcaggaaacg tttttgattc ctgcagaaaa tgtggcaaat gttatgtatc atcatccatt
    18961 gtcccatggt ttacttgtgt tatcgaaggt cggttattcc aaaattcctg tattaggaaa
    19021 agatgatcac tttgtaggac tagtaagttt atcagatgtg gtcaataaaa tgattgactt
    19081 gcaaacaatc agcatggacc cgttagaagg actaacggtt gctgatgtga cagaaacaga
    19141 tgttccgaca attgatgaaa attgggaact agaagaagta ctccatttgt tagtcgattc
    19201 gcctttttta ccggttgtca cagaagatcg gattttcaaa ggaatcatta caagaaaaga
    19261 gctgcttaaa gccgtaaact tcatggtgca tgaattagaa cgtcgtaata tattgtctcc
    19321 gaaaatcgaa gaattaaaag aacaaatcga tatcgtgagc taaagaacga gaaactaaaa
    19381 gataatcaaa aaataagtag aaaaaacagc gtaccagttt tgactttatc ttgaaaaaga
    19441 ggctgggaca aaagcgttta actccaagaa ataagaagga attcacgaaa attgcttttc
    19501 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ccgtttatac
    19561 gtgtttagag cgtgggacaa aagtgttctt tacttttgtc ccacgctctt tttagtgaga
    19621 ttcgttgcat cgtttgtcca aattattttc cgacagcaat tggactgttc ggaatcgtga
    19681 aaccagaagc tgtcaattct ttgacatagg agctcaagaa ctcttctttt aaggcatatt
    19741 gttttccgtt caatgcgtag cagaccgtac gaatcgcaaa attgctgttt ccaagatcca
    19801 ctaatccaaa gatagaaggt tcagtttgga gctcttcttg gtatttttca gctaatgtac
    19861 gatttactcg atcaatgatc tcatagattt tgtcatatcc ttcttcagga acaatccgaa
    19921 tatctaaaag tacttgcata tttgcacgag agagattgct gatcgtggtg atgtttcgat
    19981 tcgggatgaa atggacagta ccatccgttg ctttcagctg aagggtacgg ataccaacag
    20041 atacgacggt tccttcaatc gttaagtttg ctagcttgat gtagtcccca acatccatct
    20101 gttgttccat gataataaaa aatccggtaa taacatcact catgaaccct tgggcaccaa
    20161 gaccgattgc cacacctgca attccggcac cagccaaaag tgatccgatc ggcacaccga
    20221 tagcagataa aattgcatag ataaaaaaga aaccaagggt ataatgaaaa atagtattta
    20281 aaagactatg taaagtcttt aagcggctct cgtttagaat ggctttttta gaatactgat
    20341 taaaagactt atcaatcaga tattttccca cacggtgaag aatccaaaaa aggacgatca
    20401 aaaaaatcag atataaactt ttttggataa aggcagccaa aatggcgtcc caatcaatcc
    20461 cgtcccaaaa ccgctgaaac gcatttactt tgctgacagc ttgatctgtc aatgtctcgc
    20521 cagaagagtc tgtcgtaccg gcagttgcta ataatgaaaa cataaaatcc tcttttctaa
    20581 aatttgattc tttctgtatt gtaccaagaa gttttcaaaa aaggaaatag caaaaataac
    20641 tataatgaag gaaaaaagct gaaaataaaa tgacaaataa tatggataat gataaaatgt
    20701 ggagaaaata acgaaggtgg taagtatatg caaatcgatt ggaacaatct aggtttttct
    20761 tatatcaaaa ctccttggcg ttttattgcc aaatggaaag acggacaatg ggaagaagga
    20821 gaattgacag aagataatta cctgacgatt catgaaggct ctccagcgct tcattatggt
    20881 cagcaatgtt ttgaaggtct aaaagcttat cgtcgaaaag acggcaaggt caatctcttt
    20941 cgacctgaac aaaatagtcg acggatgaat caaagtgcta gacgattgct gatgccaatg
    21001 gtccctgaaa agatgttcgt tgatgctgtc aagcaagtgg taaaagcaaa tgaagatttt
    21061 gtgccgccct atggaacagg cgctacatta tacttgcgcc ctttactgat tggggtcggt
    21121 gaaaacattg gtgtccatcc agctccagaa tatttatttg tcgtcttctg tacgccagta
    21181 ggagcgtatt tcaaaggtgg actaaaacca acgaatttta ttgtatctga ttacgatcgt
    21241 gctgctccta aggggactgg tgcagcaaaa gtcggcggaa attacgcagc gagtttactt
    21301 ccaggaacag aagcaaaaga actggattac tcagattgtg tttatcttga tccagccaca
    21361 catacgaaaa tcgaagaagt aggtgcagca aatttctttg gaattacaaa agacggaaaa
    21421 ttcatcactc cgcaatcgcc ctctatctta ccaagtatca cgaaatattc cttgttgcag
    21481 ttagctgaag aacgactagg actgcaagca attgaaggag atattttcat tgatgatcta
    21541 gatcaatttg cagaagctgg tgcatgtggt acagcggctg ttatttctcc aatcggtggg
    21601 atttatcaca ataacaatct tcatgtattt tatagtgaaa cggaagtagg accagtaaca
    21661 aaacggttgt atgatgaatt gacaggtatt caatttggag acatagaagc accagaaggc
    21721 tggattgaag tcgtggaata atttcaaagt aatgagttga aaaaaacgta aaaagaaaaa
    21781 atcaggaaga gactttaaaa agttttttcc tgatttttat atgttttact ttaaagaatg
    21841 caacaaaagt ttatgaaaga tggacacctt tgtcaacgta gataatatca ccgatgattc
    21901 cgctggaaag tgggctgatt aagaaagcac aagcattacc gacttcttcg atcgtcacac
    21961 cttgctgatc aggcgtacga gattcagata actggatcag tttttgatag tctttaacac
    22021 ctgtgacagc taatgttttg attgccccag ctgagattcc attgacccga attcctttag
    22081 gcgagaactc agctgccaaa taacggatag cagcttcaag agaagctttc gcaataccca
    22141 tcatgttata attcgggatt gcgcgttctg aacctagata agtcatgcta acgatcccgc
    22201 tgtttggtgc aagaaacggt tgtgcgtatt ttgatacagc aattaaagag tagctgctga
    22261 tatcttgagc taattgatag ccgtctctgg aaatatcaga cacatttccg gacaattctt
    22321 ctttgttggc gtaagcaact gcatggacaa ggccgtggat ctccccagca tattcaccga
    22381 tggcattcat tgctttttcg atgctttcgt cgctagaaac atcacattct acagtgaatg
    22441 cttcttcgcc gaccaatttg actaatgatt ttttcattcg ttcattttgg taagtataga
    22501 taatttctgc cccttgtttc aacattgctt cagcacaacc ccaagcaatg ctttttttgt
    22561 tagcgacgcc cataatgacg attttttttc cttctagaaa tgacataatg actctccttt
    22621 gtttctgata aaaatttgat agtcgtaaaa aaatagagaa taatagctaa aataacttct
    22681 tgatttctta attattagtc aaaatgtttt gattgtcaaa ctattttttc ttaaattaaa
    22741 aaaagattgc taaatattta ggaatatgat actttgatag tcaaagtaat gaaaatggca
    22801 attgcctgaa agaaggagtt taattatgtc ttacgtatta tctgctactg aagtaatgga
    22861 attgattcct aatcgttatc ctatttgtta tattgattat gtagatactt tagaaccagg
    22921 aaaaaagatc gttgcgacaa aaaatgtaac aatcaatgaa gattttttcc aaggtcactt
    22981 tcctgacaat ccagtgatgc cgggtgcgtt gattctagaa acactggcac aagcaggttc
    23041 gatacttatc ctaaaatcag aagagtttct aggaaaaaga gcttatatcg gtgggatcaa
    23101 taaggccaaa ttccgtcaaa aagttgttcc aggagatgtg ctgaaatgtc attttgaaat
    23161 caccaaaatg aagggatcag tcggtacagc gttatctgca gcatatgtag atgataaaaa
    23221 agtctgtgag tgcgagttca cgttcatcgt caaccaaaat gcttgactat aaaacctgat
    23281 atagcaaaac aaaaggaagc ttacttgctt tttatgtaaa aagaagacgc ctgaatccta
    23341 gcatacgttg tcatctatgc aggattcaga cgttattttt ttatttttgt tttgcttctt
    23401 gcagtatatt gattttatcg atttttactt cttcttttgg tttgtctgaa ctatctgttt
    23461 cgatatttgc aatagcatcc acgacatcca ttccttcaat cacttggccg aagacagtat
    23521 aatggccatc tagtgaagga taaccgccgt ttttataagc gtcgatgatt gcttgaggat
    23581 agtcgtcttt taaaagacca tcatgcatat catctgtatt ttgaacgata aagaactggc
    23641 tgccgttact gttaggatct tgtgagcgag ccatagataa cgcacctctt atattataaa
    23701 ggtggttgtt gatctctgtt tcaaatcctt ctccccaaat gctttcccct ccagtgccat
    23761 cgcctttagg atcgccacct tggatcatga aatctttgat gacgcgatgg aaagtcagtc
    23821 cgttgtagta accgtctttt gcatgtgtca taaagttttc aaccgctttt ggtgcgtgtt
    23881 cgggaaataa tttgattttg attgtgcctt tattcgtcac catttcgacc agatcttcat
    23941 tttcggcgac atctttcgtc aattgtggta attccaatgc gttcaaatcg acgctactgg
    24001 cagtcgtgct ttccgcagta gatgtacttt ttgaactttc tgtagacgaa ctagaagaag
    24061 tcgtgttgtt tgcagaacaa ccagcagcaa acagcaatgc tgctgctaaa ctaatactta
    24121 aaataacttt atttttcttc ataactgttc ctttccaatt tactattttg ttatctttaa
    24181 tgataacaaa atagagggaa aatacctact taaattattg gaatttatca tttattttaa
    24241 aagaaaaaga aaaggtgtag accatttact ttgtgtttgc tataatgtaa gtggatacaa
    24301 aaacgaaaag atgcaggagg aaatggtaat atgggaaaat taggaatctc gatttatcca
    24361 gaacggtcaa catttgaaaa ggacaaagcg tacttggatt tagctcataa gtatgggtat
    24421 aaacgggttt ttaccagttt gctgcagatc aatgatgata aagaaaaagt tctttcagaa
    24481 tttaaagaag tagttgatta cgcgaatagc ctaggcatgg aagtaatggt tgatatcaat
    24541 ccagcgttat ttgaacagtt ggagatttct tacgatgact tatctttttt ccataagatg
    24601 ggtgcctacg gggtccgctt agatatcgga ttcacaggag cagaagaagc aaaaatgacg
    24661 cgcaatcctt ttggtatcaa aatcgagatc aatatgagtt cgggcacgaa ttacgttgac
    24721 aacatcatga gttattcgcc aaacacggat aatttattag gttctcataa tttttatcct
    24781 catcgatact ctggtttagg atacgaacac tttgtttttt gttcagaaaa attcagaaaa
    24841 tataatttga atacgatggc attcgtcaat tcgcaatctg ctgagtttgg cccttggcct
    24901 acgcaagatg gcttgtgcac gctggaagac caccgagatc ttgaaattgc gacacaagtg
    24961 aagcatttaa tccttacagg attgattgat gatatttcta ttggaaatgc gtacgcaagt
    25021 gaagaagaat tgaaagaaat ggcagaagca tttaacgcgg attatccaac attgaaagta
    25081 gatacggaag aaggtattac agaaaacgaa cgaatctgct tgtttgataa ccttcatagt
    25141 tatcgagggg atcgctcaga atatatcctt cgttcaacga tgactcgtgt atactacaaa
    25201 gataaagatt tcccgcctca taatacgcga gatatgcatc atggggatgt actgattgac
    25261 aatgaagggt acggtcaata caaaggagaa acacaaatcg ccttgaagga tatgaaaaac
    25321 gacggacgtg tcaatgttgt aggaagaatc tccgatgacg aattattcct ccttgacttt
    25381 ttgaaaccat ggtcaagctt taaattaatt gaaaataaaa aatagataat tagttattgc
    25441 agaaataatc cgctagaaat agccagttat ttctgctttt ttattttgtt tttttatagg
//
LOCUS       DAYYEF010000039        24909 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000039 DAYYEF010000000
VERSION     DAYYEF010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24909
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.040"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..220)
                     /locus_tag="ACHA1B_001831"
     CDS             complement(<1..220)
                     /locus_tag="ACHA1B_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFM8702591.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGN"
     gene            complement(217..510)
                     /locus_tag="ACHA1B_001832"
     CDS             complement(217..510)
                     /locus_tag="ACHA1B_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702592.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(547..684)
                     /locus_tag="ACHA1B_001833"
     CDS             complement(547..684)
                     /locus_tag="ACHA1B_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HFM8702593.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(686..1117)
                     /locus_tag="ACHA1B_001834"
     CDS             complement(686..1117)
                     /locus_tag="ACHA1B_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702594.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
     gene            complement(1131..1625)
                     /locus_tag="ACHA1B_001835"
     CDS             complement(1131..1625)
                     /locus_tag="ACHA1B_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702595.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNGKSSGGN
                     DSVILTVPEGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSAYSFVI
                     TYSI"
     gene            complement(1625..2074)
                     /locus_tag="ACHA1B_001836"
     CDS             complement(1625..2074)
                     /locus_tag="ACHA1B_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702596.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTMVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            complement(2078..2695)
                     /locus_tag="ACHA1B_001837"
     CDS             complement(2078..2695)
                     /locus_tag="ACHA1B_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702597.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            complement(2695..3603)
                     /locus_tag="ACHA1B_001838"
     CDS             complement(2695..3603)
                     /locus_tag="ACHA1B_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HFM8702598.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            complement(3616..6375)
                     /locus_tag="ACHA1B_001839"
     CDS             complement(3616..6375)
                     /locus_tag="ACHA1B_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tip lysozyme"
                     /protein_id="HFM8702599.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWMDVVQPTTVDGFKACTDPRQAAYAFERNYER
                     PAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSG
                     YLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINW
                     ARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISSI
                     VIPPK"
     gene            complement(6372..7076)
                     /locus_tag="ACHA1B_001840"
     CDS             complement(6372..7076)
                     /locus_tag="ACHA1B_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFM8702600.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(7088..9397)
                     /locus_tag="ACHA1B_001841"
     CDS             complement(7088..9397)
                     /locus_tag="ACHA1B_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HFM8702601.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(9592..10056)
                     /locus_tag="ACHA1B_001842"
     CDS             complement(9592..10056)
                     /locus_tag="ACHA1B_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702602.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(10056..10682)
                     /locus_tag="ACHA1B_001843"
     CDS             complement(10056..10682)
                     /locus_tag="ACHA1B_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HFM8702603.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(10689..11054)
                     /locus_tag="ACHA1B_001844"
     CDS             complement(10689..11054)
                     /locus_tag="ACHA1B_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97-gp10 family putative phage morphogenesis
                     protein"
                     /protein_id="HFM8702604.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(11044..11382)
                     /locus_tag="ACHA1B_001845"
     CDS             complement(11044..11382)
                     /locus_tag="ACHA1B_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702605.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(11372..11698)
                     /locus_tag="ACHA1B_001846"
     CDS             complement(11372..11698)
                     /locus_tag="ACHA1B_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HFM8702606.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(11679..11957)
                     /locus_tag="ACHA1B_001847"
     CDS             complement(11679..11957)
                     /locus_tag="ACHA1B_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0016032 - viral process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail connector protein"
                     /protein_id="HFM8702607.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(11959..13323)
                     /locus_tag="ACHA1B_001848"
     CDS             complement(11959..13323)
                     /locus_tag="ACHA1B_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0044423 - virion component [Evidence
                     IEA];
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HFM8702608.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(13336..13905)
                     /locus_tag="ACHA1B_001849"
     CDS             complement(13336..13905)
                     /locus_tag="ACHA1B_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA];
                     GO_function: GO:0008233 - peptidase activity [Evidence
                     IEA];
                     GO_process: GO:0019068 - virion assembly [Evidence IEA];
                     GO_process: GO:0019082 - viral protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HFM8702609.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(13877..15064)
                     /locus_tag="ACHA1B_001850"
     CDS             complement(13877..15064)
                     /locus_tag="ACHA1B_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HFM8702610.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEETQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(15128..16855)
                     /locus_tag="ACHA1B_001851"
     CDS             complement(15128..16855)
                     /locus_tag="ACHA1B_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="terminase TerL endonuclease subunit"
                     /protein_id="HFM8702611.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(16852..17304)
                     /locus_tag="ACHA1B_001852"
     CDS             complement(16852..17304)
                     /locus_tag="ACHA1B_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HFM8702612.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(17416..17796)
                     /locus_tag="ACHA1B_001853"
     CDS             complement(17416..17796)
                     /locus_tag="ACHA1B_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="HFM8702613.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(17793..18179)
                     /locus_tag="ACHA1B_001854"
     CDS             complement(17793..18179)
                     /locus_tag="ACHA1B_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HFM8702614.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(18181..18459)
                     /locus_tag="ACHA1B_001855"
     CDS             complement(18181..18459)
                     /locus_tag="ACHA1B_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702615.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            18507..19235
                     /locus_tag="ACHA1B_001856"
     CDS             18507..19235
                     /locus_tag="ACHA1B_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HFM8702616.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            complement(19381..19857)
                     /locus_tag="ACHA1B_001857"
     CDS             complement(19381..19857)
                     /locus_tag="ACHA1B_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="HFM8702617.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(19817..20173)
                     /locus_tag="ACHA1B_001858"
     CDS             complement(19817..20173)
                     /locus_tag="ACHA1B_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702618.1"
                     /translation="MKKVNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVL
                     KIEQNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIR
                     GGVCEISLVKRLPRTR"
     gene            complement(20151..20336)
                     /locus_tag="ACHA1B_001859"
     CDS             complement(20151..20336)
                     /locus_tag="ACHA1B_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702619.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            complement(20337..20609)
                     /locus_tag="ACHA1B_001860"
     CDS             complement(20337..20609)
                     /locus_tag="ACHA1B_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH/PUA domain-containing protein"
                     /protein_id="HFM8702620.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            complement(20606..20806)
                     /locus_tag="ACHA1B_001861"
     CDS             complement(20606..20806)
                     /locus_tag="ACHA1B_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702621.1"
                     /translation="MKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDKY
                     LGEGFCGDSLFDDERILKEETE"
     gene            20934..21146
                     /locus_tag="ACHA1B_001862"
     CDS             20934..21146
                     /locus_tag="ACHA1B_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702622.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            complement(21179..21373)
                     /locus_tag="ACHA1B_001863"
     CDS             complement(21179..21373)
                     /locus_tag="ACHA1B_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702623.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(21386..21568)
                     /locus_tag="ACHA1B_001864"
     CDS             complement(21386..21568)
                     /locus_tag="ACHA1B_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702624.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKI"
     gene            complement(21565..21705)
                     /locus_tag="ACHA1B_001865"
     CDS             complement(21565..21705)
                     /locus_tag="ACHA1B_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702625.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            complement(22195..22560)
                     /locus_tag="ACHA1B_001866"
     CDS             complement(22195..22560)
                     /locus_tag="ACHA1B_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702626.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            complement(22600..22902)
                     /locus_tag="ACHA1B_001867"
     CDS             complement(22600..22902)
                     /locus_tag="ACHA1B_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HFM8702627.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            complement(22902..23201)
                     /locus_tag="ACHA1B_001868"
     CDS             complement(22902..23201)
                     /locus_tag="ACHA1B_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702628.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            complement(23194..23358)
                     /locus_tag="ACHA1B_001869"
     CDS             complement(23194..23358)
                     /locus_tag="ACHA1B_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702629.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            complement(23364..23633)
                     /locus_tag="ACHA1B_001870"
     CDS             complement(23364..23633)
                     /locus_tag="ACHA1B_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702630.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            complement(23645..24394)
                     /locus_tag="ACHA1B_001871"
     CDS             complement(23645..24394)
                     /locus_tag="ACHA1B_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702631.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            complement(24391..>24909)
                     /locus_tag="ACHA1B_001872"
     CDS             complement(24391..>24909)
                     /locus_tag="ACHA1B_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative HNHc nuclease"
                     /protein_id="HFM8702632.1"
                     /translation="VQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGGEK"
BASE COUNT         6920 a         5310 c         3830 g         8849 t
ORIGIN      
        1 tgtttcctcc ttcttcgctt tcagccgaga acattttgta ggttcgattt gatacaccca
       61 acacactccc taaaaacgcg ccaaaaccag taatgatgac aacacagata tctgtgtact
      121 gccaattgag cgctttacca actaacccca cgaaagtagc tagtgcggga ataattacca
      181 gtgcgaacca ttttagtact tcgaacgttt tattattcat tttcttctct ccctaaacaa
      241 agttttgatt tgttgcgtgt gttccaccaa tttttctgta tgtgtatcta atctttcatc
      301 gtgtttcttt agttcttcat gaatcatcaa tcgatctgat ttgctcgatt ctaaatcttt
      361 agtcagcaaa tctaaattgt ggcttacttt tgaaagagtc tcagtaattt tcgagaaaga
      421 tgcagcaatc ggtctaatta ctaataaaat caaagaaacg atagcggtta ttgatcctgc
      481 tatcattccc cattccccta aattaatcat gtgacaactc ctttacctta aataaaaacg
      541 catcaattaa gatgcgctct tatctttatt aatgatttta tctgcttctt cgtctgtaat
      601 gcataatgga acgaaaacca ttacttgttc gttagtgaaa cagccccagt catacattag
      661 tttgatatct tcatatgaat acatgttact tcccaccttg taattgtttt ttgatttctt
      721 cgatttcctt ggtattttgt acagaagcaa gcatcgtttt tgaattcaac tgcgctaaac
      781 tttctgactt ttctttcaat aagacatttt cttgcttgat tgctacattg tttagcattg
      841 ctttagaatt tagctgtttc aattcatcat tttctgcctt cagcgtttcg tataatgcct
      901 taatattagc caattcatct acgctatcaa cagcattccc ttttttctct tcttcagtag
      961 ctaactcaac ccactgtttt ttatcaaaat caaatcttgg tctccagtta ggaactggtg
     1021 gtttaatctc tgtacagttt tcagggatat tttcttgatt gttcaaaatg atttgctcga
     1081 atccgtaagg cttgattgat ttgtaaacta ctttcattag atttcctccc ttaaattgaa
     1141 taagtgataa caaatgaata agctgatcca taacttgaat ttcttctcca tttaatggct
     1201 ccgtctgcgc caatagatag ttgagcactg ttcaaagtag aacggtctat tgacccaacc
     1261 agttgttcaa aactaattgg tgtccgatag ccttctggaa cagttaaaat aaccgaatca
     1321 ttcccgccac tactttttcc gtttaaagcc acaaaatata tagaaactgt ttttccttca
     1381 cgataaagct ttgctgtccc tgtattaccg ttagtgacaa ccagatttac cacttcatat
     1441 ctgttatcat cagtcgtcaa aacacgttta ttattgattg ttacagaacc tgaaaaattc
     1501 ttatgtcctg caatggcttg gtctccatct gtctgcacca atgcttcttt accatcaata
     1561 gcttctacat gcgtttttaa gtatttagca actccgtctt cttttaattg aacaatatca
     1621 gccattaaac cgtccccact ttctcaaatg taatattcgc taatccatca agtttcactt
     1681 tatcggttgc tgacattaaa cctgctgtcg tagttgtagc attacctgga tttttctgtg
     1741 ctccagctgc aattccatcc aacttagttt tatctgtgga cgacatcaac ccatttgctg
     1801 tagttgtagc tacagctgta gttgtggcat ttattccagg atcaccttta tctccctttg
     1861 gtaaaacaaa attaaatcta gctgcagatg atgttcctac attcgtaaca gaagcggttg
     1921 aaccactaga aacggttcct atggtaattg ttgctgcttg gccaggatcg cctttatctc
     1981 ccttcaccat tgttggtttg ccttctatag cattccaatg agtttgtgga taaacctgta
     2041 cattgctttg ttttattttt acgatatctg tcattctcta tacctcccca attttttcaa
     2101 aagtaaaatt tggaattctt tcgtttgtgt aattttctgc ttgatttaca gcttcttgga
     2161 atttttgatc tacatatgac tgattaacac caccagtccc actaccacct gtagaactaa
     2221 ttgttccatc ttctgcaatt gatatatttg cacctgcttt taatattttt agagattcta
     2281 attttccttt taattcttca gagaaattga agtctgtttg cttagttgca gataaaacac
     2341 cttcttcagt aacttctaag agttccccaa cttttatacc tcctaattgt tcaggagtag
     2401 caatcggcaa aatatatgtt ccaccttctc catttacgat cttttgaaac atttcagcag
     2461 taagaatacc atcgcttgtc tcgcttgcat aaggtagttc agtaattgca ttctctaatc
     2521 ctaaatcagc tttcgttaaa atgactgcac catatttacc attaaccgaa agaacttttg
     2581 attgtcctga tatcattttt tctaagccta aaactgcaga gacatgtgta attggcataa
     2641 attgacgttt aacaccagat tcatcagttt ccatcattct ctttacttta accatcaaat
     2701 caccccaact ttctcaagag tgaaaacatt ctgttttgga tcatcaacag ttgcaataat
     2761 caaagctcct tcttcaattg gaaattctac tgtttcaatt ttttcgactt cgtgattatc
     2821 tgaaaagaga tcgtcttgaa gaatatcagt cacttcaatt tcaccgtatt caatcgtgaa
     2881 aagtgctgct ttcatttttt gatacaaata atttagatcg gataggaaac gttcagaaat
     2941 cgattcatgg cgtacacctt gaagatctac acgtgcatcc attaattcgg ctaacattac
     3001 tccacctgga tcgatagact tcaaaatatc cttgattgat tcaaaccatg acaagtaatc
     3061 tgattcttgt ccttctctcc aatcttggaa actattctcc tgttcctctc tccagcgatc
     3121 aaattcttct ttcctttcat tcatccagtc cgtaaaatcg cctttatttt cattaataaa
     3181 atctgtcata tcagcaatta aatcttcaat tgattgccaa taagaaccca tttctccttc
     3241 tgtttttgaa acagcattga tgacaaaata agagaagtct tgagttgttc caatcaagtc
     3301 ttctccttta aatataatga aattggctgt ttgtcgatgc aaacactgca tggaatattt
     3361 atcaaaaata tatttgattt tccctttttt agcatccaca atttttgttt ctaattggac
     3421 tggatatttt ccgccaacaa ctgattcaaa atatacctta cattctgata aatcatatgg
     3481 aagaccattt tcgacaattg tagcttccat aacttcagtg tttttattgc cttgtcgaac
     3541 ttgaatcatc cccacgtaat tatagggttc tgttgtactt aatatgacat tccactttgc
     3601 cattaaatca cctccctatt ttggtggtat gacaatggaa gaaattgcac ttgcactata
     3661 atactgtcga tctaactttc cacaaatcat acctaactct gtgttttgtt cataagtttg
     3721 catacgacca ttagctaagc ctcggataac gccagtatgt ccataagttc catctgcaaa
     3781 ccatgaaccc acttgtccac ctcttgccca attaataatt gcaccaacta ctaattgatc
     3841 atatctaggg ttttgaatca ctttccaacc aacagcagac caatcatagg caataccaat
     3901 atcagatgct gcagaagtat ttcctatcac atgagttaaa ccatattttg ttccagcacc
     3961 catgccacaa ccacccagat atcctgaata ttctgcagac aagccataac actgaccatt
     4021 gccaattcgt tgtccaatca aagactctaa atgttttagt cctgcttctc cagtagctcc
     4081 tcctggtttt aaatctttaa atttgttata ccagttaact gcataatctt gacgttcagg
     4141 atgtgtcgct gccggacgtt catagtttcg ttcaaaagca tatgctgctt gtcttggatc
     4201 agtacaggcc ttaaatccat caaccgtcgt aggttgtact acgtccatcc attgtccatt
     4261 tgtaaatgtc caaataagca atcgaacttg tgcatctaag ctcgttattg gttctttaat
     4321 acctgcagca ttaaataagt tttgaacata aacttttcca tcccatgttg ctggaccaac
     4381 aagaggatat gaagaaccat cccactgaac taatccgtat gctggtccac ctatttgaac
     4441 agtatcagga tcaaaagttc ctcctgtttc ttgttgaatg ttccccaata ttccacatgc
     4501 agattgtttc gtaaatccgt tattacacaa aatatcgtat attctccaag ctctcttttc
     4561 tgcatctgtt tttaattcat caggataccc accaggtgtt tctcctccgc cagatggacc
     4621 gccattttgt cctggtatca cttctttacc tctaacagta agttttccct gaatatctaa
     4681 atcaccgaaa taatatgctt ttccgtttcc taataacaca aatccttttt ctgcagttgg
     4741 agaaattaaa atgtattttc catcgccatt tgtacgtatt accaaagaat tttcctcaag
     4801 aggtgtaggt gttacagcat ttggaaatgg atttcctgct gaatctgttg ttccgatcgt
     4861 tccaatggat tcttttctat tccagaattc catacctttt ttggttagct ccatgatttt
     4921 tttgttttca ttccaaattt gaagcgtgcc ttttacaagt tttaacacat caccataagc
     4981 attaaaggaa gtttcgaata cttctgcatt tattgttcct actttgatga agtcagcaac
     5041 aatttctcct tttgatgtga tagcaatacc gaacgggcca tttactccgt tgtctgaata
     5101 acctaagcca tttaaattcc aacgccacac tcgctttgca ttcgccacat ttggagtatc
     5161 catgataaga atctctgatg gagctttttc tggacgaaaa acgacatgcc caccagaatt
     5221 accagtgatc catgccgtcg cattcaacac attttgaact aacgtttctg ttcgattgtc
     5281 gattttcttt ttcaattctt gtgcttgagt atttactgcc gaagtgtaca gtgataaatc
     5341 attacctaaa acaatatcct tatatttccc aagcgttggg aaataagtgt attcgaccat
     5401 acgctctttt atctcgatat ctagctcttt cgccctaaca tgagcgacat caccaaagtg
     5461 taaagacgct agctcttgat acatgtcacc gtattcgagt gtgtgttcca acgccaccat
     5521 actgactgta tgagtagctt ttggctcatg gatacgatca ttgtcaaata aggttttgcc
     5581 ccatttgatc aattcatcaa ctgttttaca atctccgttt tcacgtttgg caatacgtcg
     5641 attctcgttg gttactccat caatttctaa ataaccatat tcgataggtt ctttgtcttc
     5701 atcataatcg ttatcaggaa caccgccaac caaatacaaa ctattgacaa ttgattcttc
     5761 atcaatttct tcttcgattg cttctaaatt gatgccaaaa tcaatccgaa aaccattatc
     5821 tgatccaatc tgttttacca gtttcaaatc atagttatcc atatcaagtt ccgcgctagt
     5881 cacgccagtc aaattttgat taccgttatt tgaaccaatg attgcttcaa ctggcgcgac
     5941 ttgtcttgct gtaaattggt gcgttgtccc tacattcgaa agatagttaa atttttgatc
     6001 aaatgccaaa ctgtttttaa gattggtcat gatctgagac ccattgccgt tatccgtaaa
     6061 cgacttgaca ataaagttct tattggccat aaaaccaata tgccgagctg ttacagaaac
     6121 ggaggtcaaa ttctttttga cattataaat ttcaaaatat tgccatgatc catctggtac
     6181 cttcgctttt ataaaatttc ctttttttaa ataagagcga tactgtccgc ttcttgaata
     6241 gttaccataa aaacgatatt ggccattcag cacacgattg atttctggca aatcttccca
     6301 atcaactaac gacgctccgt tcacgctcaa atcatctggc atttttttat aagcataaat
     6361 aaattcttgc gtcacagata cacactccta ttccaaaacc gcacttcttt aaattttccg
     6421 gatattttta cctgattcca ttcaggctgc aatactggcc aatcaccacg cgtaaataaa
     6481 ttcaaacctt cttgtattgc ttttccaagc tgagtatcaa ccacgattgt tgcagctaac
     6541 gtattaagta ttgttaggct tttatcaccg acagcgatcg ttatatctcc tccgttcgat
     6601 tctatttcca gatagggatg tgcaatttcg tcaccatgat caaaaatatc cataacacta
     6661 gaatgaaaaa ttttaggtgc ttcaccgatt tttcttttga gtggctgaca acgaaaagta
     6721 acatcgaatg tataaaagaa gccccactcg ttttcgaaag ggacttcttt atccatgctg
     6781 cagatagcct ctagatactt gtctggatca ttatgtgtga ttaattggct tttaccagtg
     6841 agccatcgtt tgacttctct cagtttcgaa tgtggaatag tgatcccttc tatttccaaa
     6901 tcaaaaggtt catagtcatc aaacgtctcc gtcaattctc cgcttcggcc ctgaatcgtg
     6961 taagtttcgt atcgcttgtt cggcataata tctggaagct ctgcctcaat gatgcaattc
     7021 atatcaatta ctgcattccg atttttccaa ataaaatttg gttcatctgg attcataaat
     7081 tgtcgactca aataggaaca cctcccaaat cacgaatagc ctgtttgttt gctttagcaa
     7141 atttacgatt catacgatct aactcagatg gattgtttgc atcgactttg ccaatgtgta
     7201 tatgctgttc aatgctacct ccagaaactc ttccactgat ccctttgcgt ttttcttcgt
     7261 ctgataatgg agtaactgtg gttttaccat tcttggcagt cagtaactca ggtccagctt
     7321 caccaacaat cgcttgtcca ttgattagat gaccgccttg tgctaaataa ggcagttttg
     7381 aaatagaaaa tgattttcca cctacaccag gaacccattt tggtatcttt atattattca
     7441 atccaccaat aaatccattg atcaatccaa tcatggcatt aataggagct ttccctacag
     7501 caacaatacc atcgaaaata cctccaaaaa tatcaactag accttgccat gcttttgacc
     7561 aattccctgt aaatactcca gtgataaaat ctagaaaacc actgaaaatt cgttttccag
     7621 cattataaaa attattgaaa tttgctataa caccatcgaa aaatccacca aaataaccac
     7681 ttaaaaaatt aaatatttca acagctacat ctgaaacacc tttgaagaaa gaattcactc
     7741 catcatgaaa ccatttaacg ttattatatg cccaaattag tccagtaact aatgcgccaa
     7801 tagctataac tgctaatgca aaccagcctc ccgacattcc aaataaacca gcaagtcctt
     7861 gccaaactcc tataaaactt ttaacttccc caacgatttt tgtaacagat cccataagtg
     7921 aaccaagaac gattagtact ggtccaactg ctgccgctat accagcaatt gttatgatcc
     7981 aattctttgt atcttgatct agagaccccc accatttaga gaattcctgt aataaggaag
     8041 ttgctttttc aaaaaaaggc aaaaggctta cttggactgc ttcacctacg tcagccattg
     8101 ctaattttgc attgttcata gcttgatcgg cttgatcaat tgggtcgaga gtagcatcga
     8161 atgtgtctcc tacagctccc ccactttctc cagcagtttt tgctaaatct tccaggttca
     8221 aagtacctct acgaattgca tcggccattc taggaccgcc tttagtcccg aatacttctg
     8281 ctgctgcatt gatggcttct gtttcagaac ctgcattttt taccttgtct tgtagttctt
     8341 ctagtccttg acttaaagat tttccgtctt tcgcataagc cactgttgct ttagataaac
     8401 tacttaaagc tgcgcttgaa tcaacaccag attgctcaaa ttgtccaagt aaagtgaccc
     8461 cttcaccaaa gctcaaccct aattgtttaa tttgtggtgc gccatcaatt gctttttgca
     8521 tcaagtcgtc tacagattga ccagtattct gcgatgtttt cgttgttaca tcaaggacag
     8581 aattcaaatc atcatattct agtccataag catcaatagc ttgtcgagca gatattgctg
     8641 attgcgaaac atctgtatca ttgatttcag cgtactgtag gagataattg gttgaatctt
     8701 ccagtttttt atccatgaat ccaaattgtg tatttacctc accaatagct tccccaaccg
     8761 tttgtaaagg taaatgagta tttgaaccaa cgtttttgaa agactgtgaa agtctatcag
     8821 cttgatcacc tgttgctccg gtttttgtaa tgatggtatc aagtgcctcg tcaacttcac
     8881 caaatgctgc aagtcctgct gctcctgccg ctacaatagg cgcggttact ccaacagaca
     8941 ttttttcacc aacgcctttt actttctcac ctgtttcttc gattttctgg agtttttttg
     9001 ctgtatcaac agaaacgtca ccttgttctt taagtgcatc gttcgtctgt tctaatgctg
     9061 tacgaagttt attttctccg gtttcagaat tgagtaattg tttataaagt ttttctgatt
     9121 cagcagaata ttcaccggtt tctttgacag atttttcata ttcctctctc agcatttgag
     9181 atcgttgttc agccaatcct aattgttttt ctaatttttg tttagccgct cgcaattttt
     9241 ctgtttgagt tgcatccttg tccatcgcag acacttggtt tttgtactcg gcagcggcta
     9301 agttcatttc tttgttgatt tctttgattg ttttcgaata actgacttcg ccattcgttt
     9361 taaaattaag aacgacatca gattctttac cagccattta tcttagcgct cctttctacc
     9421 accaaggcga tttatccata gttacagatt gaggtggttc aaaatcggtg ttttgttgta
     9481 accactgtaa ataagatttg agccacaagt taggtgtaga ctttaaaaag aaactctcac
     9541 tccaattcaa tagagtgaga gcaacgtaaa tataaaaact ccaaggagtt cctatctctt
     9601 ccgattcttt ttgtttttct ttctttttgc ttgcgctttt tgaaagtctt gtggcttctt
     9661 ggattttttt aggtcttcca cctgaaatgt ctggctagca aaaatttcca tacaggtact
     9721 ataagcagac aacacctctc cactcattcc caaaaatttg aaaatagttt ctggatcttc
     9781 ctctaaacca ccagtacgca gcatggcata aatcaaggca cgcatgattt ttagatcact
     9841 aggcgataag ttagcagaag aaatttgtcc ttctttttta gatagcatgg cgttcatatc
     9901 agattcaaat tgcgaataat ctccaccata cacatctgct ataaattcca tcgtttgcat
     9961 agtaaatgaa atagggaatt ctgcgccttg aataattaca acagcagaat tttttaagtc
    10021 ttcaacgtga attccataat cagataaccg agccattaac ccgcacctcc aactttagcc
    10081 aatgttttcc actgttcttc atcgtataca ggttgagcaa tgaatttatt aaataattct
    10141 agagaagctc cgtctctatt tgaatcaaaa cttgcataca tcacattatt gtatttcagt
    10201 ccgatggaaa ccagatttgc agttacatcg tcaatttttg tttcttcctc tgcagtggca
    10261 tactcttcgt caatcacatt ggatagttgt gtattaggat accaaactgc ttttttaccg
    10321 ccattttcaa tatttccaat aaatccaaag gcgaagtacg gaaattctcg tgcggtattt
    10381 ttgctaaacg ttactccgct tttagcaact aatcctttga tttcatccat cacttctatc
    10441 ggaataccca cgtgatccaa cgcaagttca tgttttgttt ctcgcgacac acgacgaaac
    10501 attttgctgg atgcccattt ttctaatgct gttccattcc ctttgacacc gatttttgtg
    10561 gcaattggca atcgtaaaac ttcactataa gtcggtgcag ttccaacaga atctggcgtt
    10621 gccatcatcg caattaaaat gtcgtccaat ccttcaaaat aaaaagtatc ttgttttccc
    10681 aattaaaatc acccttccca taaatcaagt atttttctag tcataatttc ttcaattttt
    10741 tctttgtttt gttcatacgt accacttgca aaatgttggg cacgttgatt tgttgtgcca
    10801 ttttcggcaa agcgccagta aaaggccgtc tcttcaaatt gaactttcac ttgatcgttt
    10861 tcaactacta cttttatttg atcgcgcata tgtttctttt ttaagagcga cttaggaata
    10921 ttaggaagca actgctttag ataaaagtta gctgcttctt ctaaagattc caacgataat
    10981 tttttcggat caacttttga aaggtttcct aaataatccg atatttcaga aaaaccattc
    11041 ttattacttg gcattttcca cacacctcac atatgtgtaa tagttggtta cggtatcgtc
    11101 gttctcatca ccttgtatac ctgtaaaatc tgaatatgga atgccagcat tttgcagcgc
    11161 ttgttcaata acaactaaat cctgttctgt tccaagtgta aaaaaagaga cttggtaata
    11221 aggtaatttt ttatagactt taccggatgc catttttttg ctgttactca catttgagta
    11281 cacaatgtat ggatacatcg tccctaatct ggctttgtct ctgaacactg ctaactttgt
    11341 tgatttcagc gctgttttca attcatcaaa gctaatcgac ataagctaaa ctcaactcca
    11401 tttctcttgc atcgggattc gtataaatgc gagtaatgtt atacgttaca gaatcaattt
    11461 tgagcgcact taatttctct gtgatggatt tatcccatct gactttaatt cgtctgacaa
    11521 cgtctgtctt ggcttgctgt gataaatatt tttcttgaga agtcacaccg agttcttcat
    11581 agaatattag acgcttaaat tcgtaaattg tagttggacg atcgtttccg tctgttcctg
    11641 ttttgatgtc tagcaattcg gctttccatc tgagattatt agtctgtctc ttcggcattt
    11701 tgaatcgctc cttgcacgat aaatggcgtc atggcattca tagctttgtc gagttcatcc
    11761 tctgaaactc tatattcata ggcaatgccg gcaaccatca aaataagata ttcttgttgg
    11821 ccaccagttg ctgttttgac ataatctttt gccatattta aataaaaaga gagcaaagaa
    11881 tcatccatgc cctcttcaaa atgaatatgt gatttgaatt tttcctctaa agacaattct
    11941 ttagtttgct cttccatctt aaccaccaac tggttttgta atttcgtagc gatatactgc
    12001 cggttcaaat ggagaataaa ccaattgacc atctagcaag ttgtaaattt ggaatccaat
    12061 ttgattttta ccagagaatt tttcaacaag tttttgaatt tccaaggcac caataacttc
    12121 ttgaatttta aatgcagaaa aatcgccaaa atataaaact ggcgtgtctg gttcaccctt
    12181 tttatctgct gcatctgtcc aatccacagg atagccaact aattggtaac caattccacc
    12241 ttctgcttgt gtgaatggcc gcaacaaagg aaatccatca tctgttttca ttttttcaat
    12301 ggcagtcaaa gcagctcgat taataataaa gcgtcccttt ttcatcactt ctgtcactgg
    12361 tgtattttta aattcgatta atgcatcata taatttttgc ccagcacctg aagcagttag
    12421 atctaaaggt tttttaaatg ctacagcctt tttggctaat gcaccaggat tttcatttcc
    12481 agcgtcatca ccattgaaca tataattgat ttctttacgc acataagctt ttttcaattc
    12541 ttccacaaca atatcttcaa ctggaacacc agacattttt aataattttt tagttactgt
    12601 tgccaaagca tcgaattcgg caggattaag caaaatttca tcaaactgaa tagctgtttc
    12661 agcaatatca gttgaacgct ctttcttgtt tacattcgca tctgctttct tcacaagaat
    12721 tggatatttg acatctcctg atgttcgcac cactgttccg tatttacgaa gtaaattttc
    12781 ttcttgagca taagtaataa cttcagatgc aattacttct gggacagtaa ctgaaccgtt
    12841 gccagcttca atccctaaag ctcgagcttc tgcttcagaa atatttccag ctacaaaatt
    12901 agcaaatgct tttcgtagtt gttgatcttt ttgtttcttg gtcatttttg cacgtgcctc
    12961 caatccgttc ttaattgatc caagtaatcc atctcgttgc tgttgagtaa tcattccaga
    13021 acgattttct gaactatctt cactgtctga atcttcttct tgatcgttgt cttcaccaga
    13081 acggctttcg tctgaatccg tactattcga ttgatcatct gtattgtcgt ctgtttcatc
    13141 agttccagaa tctgcgccta attcgtcttt aattccgttc aattcatcaa taacactgtc
    13201 aatttcttct ttcacggctt ctaaatctgc ttcgcgtaat tctcctgatt caactttttc
    13261 acgtaattca gtcaatcgtt gctcacgacg tgccttcatt tttttcaata attctttatc
    13321 catgtatttt tcctcctacg cttctagcgc ttgattaatt tttttgatta atttttttct
    13381 ttcttcgacg tttttttcta attcatcacg acttcttaat gcagcttctg tatcttcgta
    13441 tgctggcaaa ggcacaatag aaacctcgta taattccact tcatggattg ttcgaagcat
    13501 tggttcagaa ttgtagtccc acgtttcttc agtcggcaca aaaccaaaac tacattggtt
    13561 gatgtctcct cgttccatag atttaactaa gtcccttgct accgttgtgt ccggtaaatc
    13621 aacttcgaat ttcaaaccac gttcatcttc ttcaaggcga agggttccgc ttttagtacg
    13681 tcctagcaca ttggaccaat cgtgattgaa caaacaacga acatccgaat tactaattgc
    13741 ctttgagaat gcaccaggaa caatcacttc gcttaagtca tcccataaaa gtgtttgact
    13801 gttgaataca gcagcgtagc cgctaatggt cctcgtatga gtttcttcat cggaacgtgt
    13861 tgaaagattg gtgatgtcaa tcgtgcgaat ttccttcttc ttcatttcca tcacctcctt
    13921 tcaagtcttg atcattcgtt ggtaaggaat catctgttgc atttttctgg ccaatcctag
    13981 ataagtcatt tgaaatatag atagcttgtg tttctggagt attctgttta ggaaaaccaa
    14041 gcatttctgc cacgttatct ggacttgtaa tcccggtacg aacgatgttg tagccaatat
    14101 ttgtttttgt tgagtaagga acaaaatcca aaatattaat tttccattcc actctatagc
    14161 cagaattagg cataaaaaaa agagcggtgt aatgttcgct cttgtttttc aatattggtt
    14221 tgattgcttt gttgtgcaga tacatcatcg ctttttcaat atctgtcttc atcagcgatt
    14281 gatacgtatc aacattgatt cctagaaatt ttcctaagtc ttttttgtaa acacctaaat
    14341 aattcaaaat tgccgcgtca tcaacaggac tttttaatgt ctcgatggaa tatccttttc
    14401 ccaaaggaat catcttaaca gaatgatcac tctcattttg cgtttcttcc agttgatcca
    14461 atatagcttt gacaattttt gtttgggcgc tattatttgg attgatgtgg gcgtctagtt
    14521 taagcatgaa cgcaagtaaa ccgcctttag tatatttgtc cgtcaaaact ttttcagcgc
    14581 tcagaacgcc ttctagagtg tttcttgcaa gatcaattat tccagcacct tttaatgaat
    14641 cagttccgat gttcttaatg tgtcgaatca tttgaccagg tattttttga ccattcattt
    14701 caaattcttc ttgaagtcgt tcattgattt tagttgttac accgtacgcc aaatgaagct
    14761 gatccctatc cgttaatggg aatgtctcac cattgatcaa taaagtattt gtttccaatt
    14821 tggtaaattc gaatcctgtc aaataatcat tgggactctt caaaatattt agtaagtgat
    14881 gatctttgac ttcgttgccg tcgggaccaa taacaattgg tgtggccaat gccacctgat
    14941 tagatatgtc ttgaactaat tcataaacat cagaagattc catgatagat gaatccgtca
    15001 catatctttg accataacgt gtgtagtgtc caaaaatatc ctcgatatat ccacgttttt
    15061 ccataaaaga atagactgca ttcgataacc gatcacgtaa tttcaatttt tttcaccgcc
    15121 tttctattta tctatagatg gaacttaggt aatcatctaa ctcatctgaa tcaatatctg
    15181 tcatttgatt catcgtttcc ttatgaccac acaaaaacgc cacgaaccca tcaatctttt
    15241 tctttgattg acgtttactt ggcgcttttt gtccattgat gttagtaatt gctacaacgt
    15301 tcaaagtgca ataaaggaat aatggattat caaattgaat tcgtttctca taaaacaacc
    15361 gttcgacatc gtcaaaagga gcattcaata ctttaggata ttgagcaact tcaacgcatt
    15421 ccaatcctaa gttttctaat ttctcaacaa gtttgtcact catcgctgga tcataattca
    15481 cttgctgaat atcatataaa ttcatgcagt cctctatgta ctgcaaaatc tgatcttgat
    15541 caatcatttt tccgtcgcaa aattcaacga aaccttgttc agccaaatca ctgtaaggaa
    15601 cattatcttc tttttctcga aactctaaat cttcattcgg aataaaataa agttgcttta
    15661 ctttaagaac cgctttacca tcttcatccc atgttgggaa gtttaaagat acacaggtca
    15721 aatctcgtgt acgtgataaa tctaaaccga tataacatgg ttcgccactt aaatcaccaa
    15781 gttcttgtgt ggtaactaaa catggctcta cttgatcctg ttcaaagaaa ttatccgcgc
    15841 cgttcacaaa tacatccaag tgtttcgtta gaaattcagc tttggaatga gctgaccgtt
    15901 gcgctgtttt aaatgccgat tctaaagcag ataaatcgac tgatattccc cagttaggat
    15961 tgcacatttc ccagactttt ctatccgtcc aatcataatt tttatttggc tcatagatta
    16021 gaacaaagtt tgaatcatta tcatcacgtt tcaacacttc ttttgcttcg cgatatacac
    16081 gcattccaac agacgacgaa cctttcccag cagttgagat attaaacatc aatggctgtg
    16141 gtaaagatat ctgagcagac ttaaaattgt catactgttc cattttctcc tgtttatgca
    16201 attcatcgtt caatacaaaa tatggattgg atccctcgat attatcaata ttcttggttt
    16261 gaacaataaa tttatttgag taagccatat cttcatgaat atagtcataa gtaatactag
    16321 aaacagttcc ctttggcccc ctaaatattt tagttccttc aagtaggatt ggattgttta
    16381 agattgtaac tgcaaaaggt ttggcagcat attgcgcttg agcaaaatca gatgcgcaag
    16441 catagcaatc aactgataac gccccttctc cgtacattgc atatcctaat gaaccgacag
    16501 caatcaatgt tttaccattc ttttttggaa tctggacata agcctcacga gtaacgcgta
    16561 caatttggcc tttttcattt tctttaaccc aaccataaat ccaagaataa ataaattttt
    16621 cccagggttc taaaagaaac ggttttccca ccatttctcc ttttgtgtga acaataaatg
    16681 attctaccca atccatcatt tcattcgcgc gatctacatc aaaccaaata tcttttcttt
    16741 ttttccactg ataccagcga tctattgcta aacgaacggt cttaggatac ttcttaggtt
    16801 tctttcttac ttcttttgca aataaatcag cataatttac accaggttca atcatttttc
    16861 agcacctgcc ttcttacgcc atttatttct gtgcgctgct agttcatcta ctggctttac
    16921 ttctgggcgt gtaatttctt catcttttct tgcggtcgat cctccagcaa ttagtctacc
    16981 agtttttgct ttgtttgtta atcctaataa atctagagct ttcatcttct tatctgccca
    17041 agtttctact tgttgtgcca atggatgttt tgattgatta gtagctcctg atttattcgt
    17101 gaatttttgc gtctccggaa atcctttttc cttccacaat aaatatttgt gttggtaaat
    17161 ttcaaaaata tccaagtatg attcgattaa tggatcaaga gtgatggtgt acaaatcaga
    17221 caaattcatt atttctaaga tacgagcttt ttcagcactt actttttcat caataatcgc
    17281 tttacgttgc gctttagtcg tcatttttgt atacaccccc ctttgttttt tgaaaaattt
    17341 gacctaacga tgcgcgtgac tccccgctac cctatctccc cacgcgaaaa aattttgaaa
    17401 atgaataggg gggcttcaat tgaaatacga aggaaaaact tttttgtctt ccgtttcgtt
    17461 ttcaacaatt ggatgacatt ttgaacataa tagcatgaga ttgtttggat caagcttaag
    17521 cagttcgttg tctttgattg gtacaatgtg atggacgtgt gctctctttc caaatatgaa
    17581 ctgaccacac cgctgacaat gaccaccttc tctttcataa ataaattgac gcatatcttt
    17641 ccatgcttgc gttcgataga atggtttgtt ctcatgatga taaacagact ttgcttgctg
    17701 cttcttcttg cgtgatctgc ttgatctctt gtgttcagta cagtagatac cctttgctat
    17761 tttgttcgtg catccgtcaa actgacagta tttcattcta cttcacgaat aagatttatg
    17821 atatcgcctt ttgcacggat agcaccagga atatcaatac catgtttctt agcatatgca
    17881 cgcaattctt ttgcagtcat attgtccagt tcatccgtat cttcagtgga ctgatcatta
    17941 gtagcttcgt ctccatcaaa attagcagca gtgtttccat cgctatcaag aatttcactg
    18001 ctatgagcta tgagttcgcc attgacagca acaaatgatt tgccatcact caaaattcct
    18061 ttttcttctt ttacttcaaa atttggttct tgatctttcg gaacaactac tgtccttttc
    18121 ttttctgaat cccaatactc tgttccacta atggatgttc taattttgat cattgccatt
    18181 ttaattctct cctttgtaat ttgtacggat tacttttgcg cccattcgct cataccattc
    18241 aatcgtttcc tgcagattgg gtagagtgtg tgacaataaa gaaataacta acgtattcat
    18301 tccagttctg taatcatcat tctccacttg cacatgtgca tgattaccat tccaattttc
    18361 tctgtacgga ctattctctg cttcaattgc tttcttataa actttagcca aacttgattc
    18421 tacttcaata ctaagtaccg cttcatgaaa atcattcatt tgtttactct cctatcagat
    18481 attttgtggt atgatttata aaaaagatgc gaggtgtttt aatgcttcaa gaagttaata
    18541 ttaagtatcg tgatcgtcaa aatacagaga caatttattt gccaaatagt tgtccgcatt
    18601 gcggaaatat aatgactccg tatgtgtatt ttggggtttc atcatatagt gcgttcgata
    18661 atgatagaat ctttggcgta ttagtacagt gtataaatga tgagtgcaac aaattttata
    18721 gtttacaatt tataaatacg tttaatgaag atgaaggata ttctgaaaat attttaatta
    18781 aagattatta ccgtccgccg attaaaatag atttaccaga aaatattgaa aaagtttctc
    18841 ctacatttgt tgatatttat actcaagcca cacaagctaa atctgagcaa ttggaacaaa
    18901 ttgctggagt tggttataga aaagctctag aatttctaat taaagattat gcaatatcta
    18961 aaaattcaga ggatgaagat aaaataaaaa aaatgttatt aggtaaaaca attgaaaatt
    19021 atttgaatga ttttcctaaa ctccaaagat tagccaaagc tgctacttgg attggtaatg
    19081 atgaaacgca ctatgttcgt agacatacta ataaagatgt tcatgatatg gatgcattta
    19141 ttaaatcagc agcgcaattt atcgcggctg attatgatgc tgatttagct gatcaattta
    19201 taaatggaaa taactttatg ccaactacta attaaaagaa taaaagagcc acagatacca
    19261 attaataaaa cggttgggat atcttggctc tttcatattt ttttgacact aatagaatat
    19321 catgctgcta acaatgttta catagctaca atgaccgaac atttagtgaa cagtgtaatt
    19381 ttagaataaa gagagttgtt ctttgtactt ctcgctattg taaaaatcaa tttcgttttc
    19441 ttttttcaat cggtcagctt gtctgtgttc atactcatct aaaaagttca atgtctttct
    19501 aatttctgca tgtcgctgtc tgacatacga tgagctatac ccaacagatt cagcaatatc
    19561 ttctaagctc atttgatcaa catatttcat cttaacaatt tgattatcga taccagaaaa
    19621 gctatctatc agcaataaca tttcttcttt ttgctcgatc aacaattcca attcattttc
    19681 tatcttttgg atattctctt ctaaagaaga agttctcgaa ttcttttcga tgcggacgtt
    19741 tgctaaatca ccacagaccc atcgattcaa ttcaagctta cttttattaa gattccactt
    19801 taagtaaaga atctgctcat ctagttcttg gtaatctttt aaccaatgaa atctcacaaa
    19861 cgccacccct tatggtagaa tagtattgcg ctgctatctc gaaaggggta gcttttttat
    19921 tttttcttag ccgttccatt ctggattgcc ttttgttcca aacgtcgttt tttcttctta
    19981 atctttgatt ttgtttttcc catacaattc tcctttccga aaacacattt tgttcgattt
    20041 ttaatactaa ataaaagttg gccagaattt ttcgttcgtc tttactcatc tttttttgaa
    20101 taagattact agcataaaaa tagttagtac cacgaaaatg aacaggtaaa tcaattacgt
    20161 tcaccttctt catgccagtt atcagccact agaatctttg cgttagtgcc gccaccgttt
    20221 tcttttttgt atttttcaaa tgctttataa gcagctgttt ttgatttata gatttttccg
    20281 gaaccgactg ggaacatcca tgtgccctct gtgatagcta agatgtatac tttcatttaa
    20341 ttcacccctt taatccccaa cactacatat ccggacttct gcatgtaatc agtaatataa
    20401 gtgatctctg ctttgtatga gtcaccagtg taactaaatg ttggtctcgt tagtccaggt
    20461 aattcatgtt taatgtattt tttatattca cgtagtatta actgatcacc aactttgaag
    20521 tcacgatcat tcttgcggat ctcgaattgt ttgcgtccgc tcgtcactgc ttcaaaatat
    20581 tctggtagta tttttagttc gtggatcatt ctgtttcctc cttcaaaatt cgctcatcat
    20641 caaaaagtga atctccacaa aatccttctc ccaaatattt atcgttcatg tataagtcaa
    20701 ccaaatattt gtgatctgct tctcgatatt cattaatatt aacgatcttt attttgtaaa
    20761 cattaccttc gtcgctcact atcttgaatt gttctctgac tttcaccacc gttcctcctc
    20821 tttttgaaaa aattttagtg tttttgtaag accccctaaa tcagcttttt tatttgatat
    20881 aatacttgta tcgattaatc aaatcgaaat taaatttaaa aaggtgattt atcatgaata
    20941 tcaacaattt agtaaaactc gttgaacaac gttttaaaga atcaggatta gaacaattaa
    21001 aaaaagataa ttctccagaa ttattttcta attttaccga agacgacatt cctactctta
    21061 aacaattaaa atattattct gattattgga cgcaaactcg tgagaatgaa ttaaatttag
    21121 aaaaactcat tattaaaaag aaatagcaac tccagcccac acggctggtt ttttagtttc
    21181 aacttccctc cttacgggtc aaaatcatcg gttccggcat aatctgatca tcctttagca
    21241 acaaatcagg atattttttc cttagcttct tattgttcgt gtaagttttc aatagccatt
    21301 ggttggcttc gcttttgctt tctccagaaa aataaatttt ccctgtttgg atgcctgcaa
    21361 gttgaatcat cattttcacc tcaaatcaaa ttttttctgc tagatggagc aaaagcaatc
    21421 cgacatcaag aatcttttga cccattattt cagctacttt gctcggctta actccttgag
    21481 aaaagagcaa gcgtgcttgc tctatctctt cgtgagtcca aataaatttg gcttcctcaa
    21541 ggataattac tggatcagtt gctctcattg ttcctctgga aaaatgatgt cattcttatg
    21601 cttggaccag gtatctgcat atggaacaaa gtattgtcta gctaattcga tttgatcaat
    21661 taaagcagtt tctgataatt catggtctgc agcaatttca ttcatactat cgccttcatc
    21721 taaacagata agaccgttga cgttatcgat ttttacattt gtgactgctt gactttctcc
    21781 acgctcataa tattctacag ttgatactga tacatcagct tcggagttta attgcagaat
    21841 ctgttactgc cgggataatt taatattctt ttcataattc accttttttc ctactgacat
    21901 cgaatatttt tcatgttatg attagccgtg aaaggagagc tatattatgt gtttacacat
    21961 gatgtcctta gctcattcgg ttctttggaa gcttttttgg aaataactct caggttcttg
    22021 acgcaaatct catttattct ttgaaacaaa aaacttccat tttccgagag ctttggatca
    22081 cttcaaaaga gatttgcatt tatatttctg tgaccttgag tcgcgtaaag aaccttacag
    22141 caatggcggc aattccactt tcaggaaacc gccttttttc attgatattg gtggttagcg
    22201 gactacccat tttctttcgg cagtgccaaa ccacaaatga tctgtgttga tgtttaggta
    22261 gttgtatacc agataagcta aatccaaagt gcctgcatct tcaagacgac aatattccaa
    22321 aaattctccc atagctggac ataaaaatcc tggagctatc atatcccaac agttaatagt
    22381 gcaaagaaat tcgtttagct tctgaacgtt ttctttggtt tcacgaatta caacatactc
    22441 caattcttct ccgctggcag agcattccaa aacttcaaat tgattaagaa atggtagaac
    22501 atatgcttca aacatcaaca ttccatcttt ctgtttttgc acttgttttg catcaatcat
    22561 gtctatcctc ctattcagtt atttcttcca ttaatggaat tatttcaggt cactggactt
    22621 aacgaaaaca ccattgacca tctttccagt ccgacctttg atttcgtcat aagcaaaatc
    22681 caagcactcg tataaatcca tatcattttg cattgccaag atgatcaagg ttactactac
    22741 atcgccaatt ccgtctctta aaccatgttc atcttttcta gctagagaag cggcaacttc
    22801 cccgatttct tcgaccgttt ttaacatttg cttgctgaaa tccgcttgat ccaatccctt
    22861 atcttttgcc cactgctcta ctttcgcgat tagttcgtcc attatttctc ctccacatac
    22921 ctaaactgtc ttccttttga atcaatccat aagctcctag ctctatccca aataatattt
    22981 ttgctcagac cagtaatttc agataactgt ttagcggtac ccgttactag aattcgatca
    23041 ccatgccaga ttgcaatctt tctcggcgtt ctccgtttgg gcttttcagt ccacattgat
    23101 ttaccgagct tttggacttc tgcaactatt tttttatctt cctgccaatc ttctgaataa
    23161 gtcaattcga taattcgctg cattgccgct ttcttatcca tcccgacatt ctcctttcag
    23221 taatttgagt acttgatcaa gtgcgctctc acgtccgcca tgaaatgtgt tgagccactt
    23281 gtcttcgtac gacacacttt gtcttaaagc ttcttgatgc attaattcga tctgtgctgt
    23341 aaatgtcttt aggtccatct tgtttacacc tgctcaagtt cattaagatg tttttgcaag
    23401 cctttaacac aatcaatgaa tagtaatttg gtatatgcta aatttcttaa ttgcgttcca
    23461 tcgatataga gtgcgaaata gtatctgagt ttactccaac tcgaacgatc attcttaatt
    23521 ccttcaattc cagcttcttc gagttgatca tatacgtctc tcaggacgtc taattcctcg
    23581 ccctttttat aattcgctat ttcattaatt agttctagat aatcgatctt catttttcca
    23641 cctcttagaa tggtgctttt gattgtctat tagctcgttc tagcgctttt ttcttgagat
    23701 aggcttcttg gtcgattgcc cattcaggaa gcttctctcg tcttcctgtg cgcttgtatc
    23761 cactgcttgc gttcttaggt tcactttttt ctttccttgc ccaacttcga atagttgcca
    23821 aatagttttt ataagtctta ccagatgatt cacaatactc tgacagtcgt tcgattcgct
    23881 cttggtaatc attagggaat tctgttttga gtttctccat ctgctcatct gacaaaagaa
    23941 catttttata ctctccgtat ttatgacgga cgggcttagc cttcgatttt ttcgaaggcg
    24001 gtaactctct tatatattct tttgtattat taaatgtatt attaatagat gtattattat
    24061 ctttgacttt ttcgtcaata ggggtattgc gtttttcgtc aatagggtat tgattaattc
    24121 gtaggtacct attgattatt tgattggtac cctctttgta aatgatttcc cgattcaagt
    24181 atccaaactt aatcaaatca cttacccatc gcgatatggt ctctttattc acaccatata
    24241 aatctgcaaa gtactcattg cctgcccaac aaaagcctct ttcattacac aaggccgtta
    24301 tctctccgta taacaactta gtatttggtt taagtctttt gtcgtacctt acgttggctg
    24361 gtataatcgc ataataactt cgatgttctg tcatttttcc cctccaatat ttaacttttt
    24421 gattgttttc tggtttaatt tgatcccttt gatttgatat ttatttttga aattaatcac
    24481 acctattttg tgcttctctg tgtgatggat tctgcagagt gctgcaaatg tgtactctgc
    24541 atgatcaact tctttgcgct ttcgtcttcc tagcgctttg tcaaagtgat cgatgtcagc
    24601 tcctgttttg ccacagatgc agcagactct ttttgtgatg catttgtaga agtaatattc
    24661 ttgattcgca ggtaaaatct catagccttc tttgaaagga atatgatgtt caaagatgaa
    24721 atctaagatg atatttgcta agacattggc atcactcaca gttgtattcg attcgtcttt
    24781 caggcttatt ttgcgccctg tgacaccttc aaaacgaaag tagaagaatt ccttccagaa
    24841 gtccgttggc atgcctgtat cgataaaaat atcgcctatc agcgcataga tgaagtttcg
    24901 ttgctgtac
//
LOCUS       DAYYEF010000040        24476 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000040 DAYYEF010000000
VERSION     DAYYEF010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.041"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1359
                     /locus_tag="ACHA1B_001873"
     CDS             <1..1359
                     /locus_tag="ACHA1B_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HFM8702633.1"
                     /translation="LFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLPITEKE
                     HLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEKEGLSS
                     FKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRDNITNW
                     HIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKDSQHPI
                     VYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFFEAIPK
                     GKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWMATIDP
                     VAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHSTSLEG
                     ARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDVQQHFS
                     RN"
     gene            complement(1432..4005)
                     /locus_tag="ACHA1B_001874"
     CDS             complement(1432..4005)
                     /locus_tag="ACHA1B_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HFM8702634.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIPE
                     K"
     gene            complement(4227..5111)
                     /locus_tag="ACHA1B_001875"
     CDS             complement(4227..5111)
                     /locus_tag="ACHA1B_001875"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HFM8702635.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(5206..5643)
                     /locus_tag="ACHA1B_001876"
     CDS             complement(5206..5643)
                     /locus_tag="ACHA1B_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702636.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(5860..6771)
                     /locus_tag="ACHA1B_001877"
     CDS             complement(5860..6771)
                     /locus_tag="ACHA1B_001877"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFM8702637.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(7148..7786)
                     /locus_tag="ACHA1B_001878"
     CDS             complement(7148..7786)
                     /locus_tag="ACHA1B_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8702638.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(7790..9772)
                     /locus_tag="ACHA1B_001879"
                     /pseudo
     CDS             complement(7790..9772)
                     /locus_tag="ACHA1B_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
     gene            9952..10617
                     /locus_tag="ACHA1B_001880"
     CDS             9952..10617
                     /locus_tag="ACHA1B_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702639.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(11014..13047)
                     /gene="brxL"
                     /locus_tag="ACHA1B_001881"
     CDS             complement(11014..13047)
                     /gene="brxL"
                     /locus_tag="ACHA1B_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005575 - cellular_component [Evidence
                     IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HFM8702640.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(13165..15687)
                     /gene="pglZ"
                     /locus_tag="ACHA1B_001882"
     CDS             complement(13165..15687)
                     /gene="pglZ"
                     /locus_tag="ACHA1B_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HFM8702641.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(15803..19435)
                     /gene="pglX"
                     /locus_tag="ACHA1B_001883"
     CDS             complement(15803..19435)
                     /gene="pglX"
                     /locus_tag="ACHA1B_001883"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HFM8702642.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(19499..23170)
                     /gene="brxC"
                     /locus_tag="ACHA1B_001884"
     CDS             complement(19499..23170)
                     /gene="brxC"
                     /locus_tag="ACHA1B_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HFM8702643.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(23195..23770)
                     /locus_tag="ACHA1B_001885"
     CDS             complement(23195..23770)
                     /locus_tag="ACHA1B_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HFM8702644.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(23770..24369)
                     /locus_tag="ACHA1B_001886"
     CDS             complement(23770..24369)
                     /locus_tag="ACHA1B_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HFM8702645.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         7463 a         4793 c         3651 g         8569 t
ORIGIN      
        1 ctttttagtg atgaagaaat ttctgtaagt gttccagaag cagctgccac cattattcca
       61 gtaaaaggac atcaacgagt tgtaggaacg aaagcagaca aaatcaaaca cttacctata
      121 acagagaaag aacatctcct tcctttggaa gaacaatttt gtgaacattg cggttcacag
      181 atgaaagata tcggacggac aaaagtacga gaagaaattc gtttccatca ggctatgttg
      241 gattgtctca cccattatca acatacctat tgttgtaaaa gctgcgaaaa agaaggactt
      301 tcttctttta aaaaagcgat cgttcctaaa cctttgattt ctaatagctt aggttccaat
      361 agtttagtgg cggaaacgat ccggatgaaa tttggtcaga aagttcctgc ctatcggcaa
      421 gagaactatt ggaaacaaac acatgggttg gatatttcga gagataatat caccaattgg
      481 catattaaag cagtgcaaaa cgcgttagac cctttaggag aacgattaag agtctatctt
      541 aatcaagaag agattctaca cggggatgaa acaagttatc gtgtgattga aagtgccaaa
      601 acagatacct attactggca gttttgtaca ggaaaagaca gtcagcatcc catcgtttat
      661 tatcaccacg acgaaagtcg tgctggagat gttccgaaaa cttttctcaa ggagtttaca
      721 gggtatttac actgtgacgg ctatagcggg tataatgccg tggaaagtgt acgacttgtc
      781 tattgtttcg cgcatgttcg gcggaaattt ttcgaagcaa ttccaaaagg aaagaaaaac
      841 acggatattc ccgcagctca agcagtcaaa caattggata aatggtttgt cctagaaaag
      901 aaatggaaag acttttctcc tgagaagcga ttaagctgtc ggcaacaaga actgcgtcca
      961 ttatttattg ctttttatga gtggatggca acgatagatc ctgttgcaaa atccaagttg
     1021 gatgcagccg ttcaatatgc gtgtaaacta cgaagtggtt ttgaacctat ttttgaagat
     1081 ggtcgtttag aactcacaaa taatcgtgcg gagcgaaata tcaaagagct ggtgatagga
     1141 cggaaaaatt ggttgcattc cacaagtctt gaaggagcac gaacttcagg aatcattctg
     1201 agtgtatata aaacagcaga acttaacgga ttgaatcctg taaagtatct agagtttcta
     1261 tttgataaga taccaaatct tcccgtactt tcagcagaaa ctttagatca actgttgcct
     1321 tggaacaagg atgtacaaca acatttttct cgtaactaaa aacgccaaac attcccgatt
     1381 ctattctata ggtcgggtta tttgacgtac aggtactgtt ctatggggcg cttacttttc
     1441 tgggatagaa agaacaaatt tacctgtatc atcaatagtt gtttcggaca aaacagcttg
     1501 attttttttc aatgaaacca aagctcctgc ttcgcctgta cctgtgattg agcgagaagc
     1561 tgcattgatc aatgtggtac ttaatttagc aggctcagga ggaatcacat cgactgtcgt
     1621 tttggcagag tccagttctg tcacttcttg gccgcctctt acttttttag cagcaactat
     1681 ttgcacttga tcccccgttg ttagtctttc ttcgttgggt acttgaacct caaacaaacc
     1741 gccttgttcg ccttctcccc acggattata tcctgtccct tcattttcat ctgtttgtcc
     1801 ttgtgtgaga gcagtaattt ctacaggtga tttcgtcgta tctgcataag taatacgtaa
     1861 agtcacttct acttcgcctg tccaagcatc tcttggcttt gcctcgacac cttcgggaac
     1921 aacgacatgc ccatagattt ttttatctgc attcgttggt actcttaagg attcaatcat
     1981 cggaagctgg ttattggcac tgattcgatt ataatttttc attccggcac ctgtctgagc
     2041 aaattcattt gttaaacctg cactagggct tgatacaaaa ttacctaagt cggttccatt
     2101 gatcgataag tctgtcatat cagaaaaata atccggatct ttttcaaagt tatcgaacgt
     2161 tactcctgcc tttcgccata aagcaatttc tgaatgagcg atcttcaaag aagaatcgcc
     2221 atttccttga aatacccagc cacctatgcc attagtctcg cttccgatcc gtttgttttg
     2281 gaaatcgaaa taggtaggag attctaagtc tacattcaac acatccccac tgatgatgcc
     2341 agtcttatct tccccagttt tcccgaccat gactaaataa gttttttcgc cagccataaa
     2401 gttcaaatca atatctccag ttgtatctac ggtagctccg gaatctgcgc gtatatcgat
     2461 atttgatttt tctccagtaa ccgtaaaatc agctgaccct ggactttcta gaaaaccaga
     2521 agcgtcataa aattggatcg cttggtttcc ttgattgagt ctgttcacat aagatttgcc
     2581 atcccctgca tttcttacct tcaatgagcc tccattagtt actgttagtt tttgcgtacc
     2641 gttctcaaaa cgaactgcgc tagaacgacc actttgctta tcaatatcga tgactgatcc
     2701 ggctccttct acgatcaaag aaagtccttt ccctacaaaa cgcatcccat tgtttccagg
     2761 ttggtcgcca tctccagcca ttttgaccga gatttgtcca ccacttgata catggatttg
     2821 actagaatct ccttgcaggc gaaatccgcc agtagtcgct gtattgattg tgattttccc
     2881 atcattcgac acagcgactc ttgatcctga gcctctcatt tggataattc cgcgattgtt
     2941 gtcgttggta atattgatct ttgtatttac cgaaaattca cttcctgagc cactgacttt
     3001 aaatgtgaca ttcccgggta gcgtatcgac agcctctcct tcatcgctga cgccatctgc
     3061 ccgatcatag tcaagagaga cctttgaacc actcaagata tggagtcctg gtgctgtttt
     3121 tccactgccc gtctcatcac ctgaatctag aaaaccatag aattttccta gatatggtcc
     3181 ataaagctga ctaccattga ttacatttag ctgatagctt ctacaaaaat aagctttacc
     3241 cggagcggca ttcatccctt ctttcactgg ttggacatcc aatacaccgg aaacaccatc
     3301 taatgtgaca gttgcacgag gggcgtaaat caggcctaat ttagaaccat catataagtc
     3361 aagtgtcccg gtaaatttta tttctcccgt aaaatgatat ctgtttcccc aaaaatcgga
     3421 catataagca atgataatgg catttccatc gatatttggt atcaacccac ctggatgagc
     3481 tgccgttcct ttaaaattct gaaactcgat cgactgaggt gtctcattga tatagatgtg
     3541 atgtgtgccg aaattatgag caagtccgcc aaaatcgata acgatatctc gcttgatctc
     3601 caattccctg tctaaagtca aaggctgagt taaacgaatc ttagctactg attcgtctgc
     3661 gagaagctgc gtcagttctt ctgttgtggc agcttcgctg tacccatccg ctgaaacaac
     3721 tctaacctgt acctcttcac tgctatcaga cgtttgttca gctacttctg aggtctcact
     3781 tgtcttattt tcttcttgcc ttgtattaga agtaggcgcc tcactttggg attctgtagt
     3841 ttcagaagta attgattctt ctgaaaaagt agtcttgtca aaactttgat tctctgattg
     3901 cgttgattcg cttgttttct ctacatcggc aaaaacggat gtcaccatca agagagggaa
     3961 gacaaacaaa atcgacgcaa tcagcttttt tacatattga ttcattctcc accatcctct
     4021 ctgacgtttt gacaatttta ttttaacgtt ttaatttatt tgtaattgta ctttcatatt
     4081 taaaatatgt atttttatgg caaatttttc tgttaggtga aaatttcttt tttgtacaaa
     4141 aaaaggctgt gacaaaagtc ttgtcacagt cccttattcc gaacaaccga tgtcctcctg
     4201 acaactcttc ggtcacaacc tccattttaa caataaacct gtaaatgtga gggtaacact
     4261 ttgattgtca caggtaattt atccccttca tctccatcaa cattcgtcgt caattcttcc
     4321 tcatcagcta atgacacaac taattgctca caagtaagat aggctagatt tttcgtagat
     4381 tcatctactc cttttaatag gtctggcaat gttttaagcg tatcgatcaa agaagaatct
     4441 tttaaataaa ccaaatggag cttaccatca tccacttttg catttggaag taatgtttca
     4501 aaaccgccta ctgagttagt tagtcctatc agcaagatac tgctctcaat ttcttccttc
     4561 tttccatcaa cttctacgtg aaacgagtag gattgtgtgg aagctaactg tttgattcct
     4621 gacatgaaat aagctagttt tccaaatttc gtcttcttct ccgcatctac atcattgatt
     4681 gcttcaggga tagagccaat tgcgacgaca ttcataaaat agtcgtcatt tatttttcca
     4741 atatccaatg gcttgactga ttcaatcgaa aaatgattga tcgcttcctc aggttctagc
     4801 ggtatcccta atgctcgagc caagtcattc accgtaccca atgggaaaaa tccgaaattt
     4861 ggccgatgtt cttgttcagc gattccactg attccttcgt tgactgttcc atctccgccc
     4921 atgacaaaca cactatgata cccttccgta gccgcttcgc gagtaaagtt ttttgcatcc
     4981 cctgcttttt ttgtatgcaa gacgaccact tcatcaaaca ccgattccaa ttttgctatc
     5041 gctaattgct caaattcctt tgcttgttca ccgcctgaac tggggtttac cactaataaa
     5101 acttttttca tcactttctt tcccttctga ttgatttctt taatataacg atagcataaa
     5161 gaaaaaaatt aggctgtgat gaagtactgt tcatgaaaca ttcatttatt ttttgacaag
     5221 ataaaatacc catactatga aactgaggaa aattaaaaca atgatatagg aaataaaaga
     5281 aaatgatagg cattgtatac ctaataaagt aaaaatctta ggtggcagat aaaaacacaa
     5341 aaatagcaag agaatgtaat agcgtttctt ccactttttg ttatcagacc ttatagcgat
     5401 cagaggaata ccaaatgcat aactgaaaaa ctcttgatgt actgttaata tgtcacgacc
     5461 ttgaataata aatgcaacaa tccccgctat aattagtgtg cctaatacca aaacggaaaa
     5521 ttgatgaata tattttatat acaaatgatc cattgtactt cctgcctttt tatttgtgag
     5581 aaaaacaaat ccgtatacgt gaataacttc tagaaataaa agaaatttgc aaaaccactc
     5641 catttatcta cttctacgtg cattttttaa tatcgttttc tttatttaag attatacaga
     5701 aaaatatcta gggtggctgg attctaagta aaaaaaattt ttaaaataaa aagaactaaa
     5761 tcaagtaata attaaactac tgttgattta gttctaataa aaagatttag atgaacagtt
     5821 ttattgattt aaatagttca tattttttat ttataccgct tatttactac ttgctgtact
     5881 agaatctgaa gtgaatgtac tcaaaacatt ttcaaagtct ttgtctttga tttttacatt
     5941 agcgtctttc aatacttcgc caattacttt attctggaag gtactgtcac ttaattttgt
     6001 gtctgttgca atttctttca attctttttt gtatttatcc atgtcgttgc ctttgttttg
     6061 gtttttcacc attttaacca cataatattc cgtagtataa gttgaagcat tggtagaagt
     6121 gatcacatca gaaacttgac catctttcaa cttaaaggct gcttctttga cttctgccgg
     6181 aaccgttgta gtagtggaat caaatttcac ttttccgcca tcttcttttg tcgtagtatc
     6241 agttgacttg tctttggcta atttagagaa atcgtctccc ttatcagcag ctttcttcac
     6301 atcttttgca tcatcttcac ttgctacttg gataatttga gcttccactt ctggatggaa
     6361 agattcccaa gccgttttta aatcttcatc ggtcaatttg atatgtttct ttagaccttc
     6421 ttgaaaggct agactttgtt tgatactgtc tttgaatgtt tgttctgtgt aacctgcaga
     6481 tttcaattgt gaatcaaatg aatcacccaa ttgtttcttt gtttgatcat attgggaatc
     6541 gatttctttg gttgatacgt catctccata tttatcttca aatacttgat aaacgatcaa
     6601 ctgttgcaca gcggaatctg ctccttgcat ttttttcaag ctatccatta cttcttgttc
     6661 gctgattgta ccgcctttat aactaacggc tgttttttca ccggcattcg tacagcctga
     6721 caataagcca gtgcctagta cgatggcaag tgctaaaaat ctttttttca tttatcaatt
     6781 ctcctacttt tcgttttttg cgaattgcta aaaacaaagg tgttcaagat gaaaatcatc
     6841 aagaacacct ttactaatct gctcgatacg tcctgaatag atataaggct acacaatcca
     6901 gaaagttcgc tcagcagaat aaatgtcaag tagcacatca caccttaata tactacttct
     6961 tttgttaccg tttttcaagt ctatcttgcg ttccgtattt aacgtaacta attcttagaa
     7021 caaatgttat cgattttgtt tttcttcttc cgctgttggg atattcaaat cagacacttt
     7081 tatgttcgat tttccagaca tttttttgtt gtttttatta gaaaaagttt gttttttcat
     7141 ttgttttcta aagcatgatc ttcttgtttc ctattttggt cagatatgga tcatgcgtga
     7201 ccacgataac taacgtacct tgggaagcct gttgcgataa gatttcaacg acttgctcct
     7261 tatttcgttt atctaatgat ccagttggtt catcggctaa aatgattttg ctattcttca
     7321 ataagactct cgcacaggcg attctttgct tctcaccacc agataatgtg tagataggcg
     7381 tacttagctt cttgtttata tttacttttt tcaatgcctc atactttgct gttcgcttat
     7441 ctgaaacatt taaattcgaa aacttcaatc caatatctaa attaaaatcg attgtttcat
     7501 attcaatcaa cccaaaatct tgaaaaagaa aagagagggc atttcttttt atcaagcgct
     7561 tctctcttcc agttaaatgt tttgtttctt gattaaataa ataaaattgc cctgaactga
     7621 attgatcatt caatcctaat atattcaata aagtactttt ccctgctccg ctctctccaa
     7681 ctacagtcac aaaatcccca gcatccgcag tgaaacgatc caaatgaaga atcgttttgt
     7741 ttcgaatgat ttttttcgca ccttttatca ctatcaacgg ctccaattgt taacctccat
     7801 tcatcagcaa taactgactt ttcttttctg tagacaaaat aaaaacaact gaaagaataa
     7861 aatcaatgaa gctaaagaaa aaaatattaa aaagatattt aggctctctt tctataagaa
     7921 aaaggaagat tacacttgtc gttccccatt tgatgaggtt catcatgaag aaatctttat
     7981 acgtttcaaa gagcgaataa ccacttgaac gaaagatagc gattttccga caattgtaga
     8041 caaaatatat gcataacatg acatagctca acaagaagaa agaaaagaaa gtgagtaaaa
     8101 atatctgtat caagtaatga aatgatctgc ttaacacttt gacagctatc tcttcagtct
     8161 gagtatacgg aaatgataac tgcaagttat cacgtaactg actttcttca atcagctcaa
     8221 ataacctttc tttcgacaaa gagcctatct tgatctttaa cggtggatag atttctccgc
     8281 tgagaatatt tctttcccaa tacgtactgt ttttcaatgt cagtatttca acaaccggat
     8341 aatgttcgat ccaggggata gaaggaataa atgtataaat gggttgattg ttttttataa
     8401 atagaaattt cggttctttt tcactgattt cttgataata ttctgttatt tgcgccaggt
     8461 cattttttaa atctgtatgt ctatatcgtt cagggatcaa tataacaggg tgcgtttctt
     8521 tttcggttat ttggatcaac cttccagaga catcaatcaa aggaaatttc ttaagataat
     8581 tcagatttat ttttatccct ctgccaaact gttcattttc ttcattcaag taatctgata
     8641 cattgactaa tatacttccg tttttattca aagtttcata taattcctga tcggctgctg
     8701 atgcaaaacg attggaataa ataaaatcca cgtggttttt cccgatggtt actggataaa
     8761 atacatgata gtcctcacca gcgatttctt ttggtgtttc atgggaaaca gctaactgtg
     8821 aagaagaaaa aacgatagtt gctaattcga cattggcaac ggtcaaaaga agagaaaaca
     8881 acaatccaaa tgtaaaaaga atgtattgga tatagttgaa cgcttctctt aacgaagcga
     8941 ttttttcaac taataaaaga gaaatcaaag agatacccta tattccgctg aacaagaaaa
     9001 cgtacatctg gaacaaataa agaaattgct ccttataata cataaaaata aaaccaccaa
     9061 tgattcctgc aattatgaat gtaataatga ttttcttttt ccccaataaa caccacaata
     9121 cttgatgtaa tgaaaagcca ttattcaaca ataaactgat ttctttattc atcaataaga
     9181 aaaaggatga taacaaaagg aataaaagaa tcaatccaat agttaaatac actcgataat
     9241 tatatacgtc tgtacttgaa ataaccgaat acgaatagct attttcaaag tcttcaaaaa
     9301 tattagtggc ataatcagtg tgaaatgctt gattgaatcg ttccacaaat agtaaaatga
     9361 accgttcata ggcttctttt tctctcgtca tcaagaaaaa ttcaccttca aaatctttta
     9421 ttttgatcga ttcttcaatg gacgttacgc gaaaggaggt attagaatag ggtaccttct
     9481 cgtgagaaga tttgacatcc ccttgataat acaatgtcat ttcaagcttt ggctgtatct
     9541 tgaagttcca agatgtatct acttcattgg attcatttac tgtttttttc atataagaaa
     9601 gctcagtttc tgatgagaca ttttcaaata ccatgattag ctgctcatat tcttcttgcc
     9661 caataaaatg ttgtggcaat cgaatcggag tataagtatc tgtttgatgg aaaaattcat
     9721 ttgtccgata gagtacctgt ttatttataa taaccaaggc aaaaccactc atgataccgg
     9781 tcactatgat tgtgagtaaa actgtgaact tttttttgat tatcaccact ctcccttact
     9841 taaatgattc tttgataaaa tcataccgtt tttcatcaaa aaaacgtatc tatcaaatgt
     9901 ataggtcatg tagaataaat ctatatactg tagaatcgaa aggagaagaa gatgaacatc
     9961 ggagaaaaaa tacgaactta ccgcagaaat tgtaagctta cgcaaaaaga attaggcgaa
    10021 aaaatcggtg tttccgataa aacaatctct agttgggaaa attctcgtac aatgccagac
    10081 cttgaaatgc tgtcactttt acatcagact ttaggtctgc cgattgattt tccttctatt
    10141 gaatcagcta ccgaatcaat agaaccaaca ttgccggatg aacctcttgt tatcaagaaa
    10201 tcttattcat caaaacaacc cttctcactc aaaaagacac tatctttctt tctgctcgtc
    10261 ttttgtttgg tctatctttt tcttatcaat tatcaatata aaaatgaaac ggttgatcga
    10321 ttcaatcctt ttttgaaacc acaaatcggc tataccacac tccctgtagg atacgtggaa
    10381 aattccatcg aacattgggt atgtaatgat atctttgttc atggtacatg gctgtctttt
    10441 cacgctggag aggtagaaaa aggtaagaat catgctgtaa tcaaacacaa aggaaaacac
    10501 gtcatgaacg ttcgcctgct cacttgggaa gccattccct cagattacca agaaatcctc
    10561 atccaagact atgacgatgc cttaaaaaga agccctcagg agccagatag gcattaagta
    10621 ggagatgaac gtagagatag aaaaaatcaa tgcacatgat cttatcaaaa aaaaacaggg
    10681 gtacaaatta attgaaaaag ctttgagatg aaagttccta aataaaaaag ttcagaatga
    10741 taggtaaaaa aatgactaac tattctagta ttaggctatt tgtattattc ttctgttatt
    10801 tttatatcaa aaaatccaga aataactaaa tataggtatt tctggcttat agtataatat
    10861 ttacgccaca gcccccaatg attctttttg gaatcatgat caaggacgga catacacaaa
    10921 aatattttgc ccattcgatc cgaatagatt aacgactaat ctagtaagta atatagattg
    10981 gtacgtagtc aaaccagcaa atggaaaagt tgtctattcc accccaaggg ctttaaagac
    11041 agcatcttcc ggcgtttgat aaaaaatcaa attaaaggta cccattaatt ctgggggtac
    11101 agttccaata tcagcagcgc ttatcatagg tacaagtact tttttcgctc cggcatcttt
    11161 tgctacttgt aaacagttag ctaaattatc taccttaatc atagaaccac caattgtaat
    11221 atcccctaaa ataactaaac ttggtaatac aggtttattt aaggaaactg agcataaagc
    11281 tattatagtt gataacgata atgtttttgt cataccaatg ccattcatat cttgaacatg
    11341 aacgacaaaa tcttttgtcg tcaaactaat agactgacta acacttccat aattagctct
    11401 taaatatcgg tatgccgaat ccatcgcttc tcttgctcca gcatctgaat tgatcccagt
    11461 acgttcaaac tttccatttc ccgaagtcat ttgcgtttcc aatttatagg tacctaattg
    11521 cccagttttg ccataagata ccgtgtacaa atgccctggc ttccctaacc cttctggaat
    11581 caaagttcct ccaccttgtt caggaacaga aacatactct tctcgctctt cttctaaatc
    11641 aatgtatgaa aaattgacat cataaaattc cattccacca attttcttta attgttcttt
    11701 tacacgacga cgcatttcaa gagcaaatct tagtatttct tcgacatcac ttttttcaaa
    11761 tctaccatca ggatacaaca gtttcatcat cccagataca atccgacgaa ctgcaatcgt
    11821 atcccgctga tttaattgag aaccaagttt gaaatattta tcaaaactat cgccaaaact
    11881 aacttttcga agctcacgca tgacttcaga aaaataatct gtaatgaagc catagtcatt
    11941 tgtaaaaaaa tctggtcgat atttaggaat ttcccaacct ggtaaataac aatgcatccg
    12001 atccaaaaag gctgaatccg tccccataac ctccggaaat ggctcaaata aattcgaagt
    12061 tttcaatatt acatcaacgc tttgattaat atttcctaca aaagccattg atgctgaagc
    12121 attcttttct tctttgcctc tagcaaaaga tcctgaagcc atgtaatctt tcatgatttg
    12181 aacgccatca ttatccttaa atttaatccc agcaacttcg tcaaaagcaa cacagtccca
    12241 catacctaca agtcccattg tacgactagc catattatag aaaaggtttg ctactgttgt
    12301 ttgtccacct gaaacaagga ttgagtttgg tgaaatttct ttatatacat gcgatttacc
    12361 tgtaccacgt ggtcctagtt cacagagatt aaaattattt tcaattaatg gaataagtct
    12421 tgctaaatga agccatttta cccttttatt aaattgtgta ggttccatac caatggaccg
    12481 tagaagtaag tcaatccatt catttgtagt aaactccttg cgagccatct tgtaagcctc
    12541 aatgtctaaa ccaggcattt ggattggatc aacctttttt gcaataaaag ggctattcca
    12601 acgatcattc tcatcatacc aatattccat cgaaacaata caccagatcc ccccacctaa
    12661 taatcgatca aattttttcg gatactcttc actaatttga acatttttta atcccaggtt
    12721 agagaattct gcttcataac aatctttctt ttcatttaaa tgtacagtta ctttatcaat
    12781 aactgtataa ccacccaatt cacgaatttt tgcttttact ttttctgctt catcaggacg
    12841 cacatagttt cgagcaagaa tatttttaac attttccaca cctttttcaa ccaatgtttc
    12901 atccaatgac gaagcataca taccaagtaa atattccaat acataaacag gtacattcgc
    12961 accttcttta attttctttg ttaaatcttt tctgacaatc tttccgggaa agaattcaga
    13021 taactttaaa atttcctgtt gttccactag aattcctcca tgtgttcagt cattataata
    13081 gcaattaaag tatatcatac ttaaccagta ggcttgataa tacaaaagaa aaagtatcca
    13141 caaaaaattg tggatacctc gtttttatat atcaaaatca aatgattctg caaaaggatt
    13201 atctataatg aattttattc gctcggtcaa atcatttttt tgatttttta tcactaaata
    13261 ataagtatct tcaactgtat atcgacgatt tacaaattca aaaacaaatt tagtaaaccg
    13321 ctgatttgca tcttctgttt ttgaatccgc aacatagatt tcttcatttg agatacgttc
    13381 accatattca tcttcaaaat aaagccagaa agatgcgggg tcataaacat cactaattgc
    13441 atttttttga tagaattcta acgtggttga taatcctgta attctgcggt tgctagtcat
    13501 taattcaatt gctactggtt cctttgcatt gctacctttg gctaccgtaa tttctagaac
    13561 agggactagc atttcttgaa tagatgaccc tccatgaacg tagctttgtc ccccgccagc
    13621 tttcttaaaa atacttgaag taatcgggac acaaatgttt ctagtgtcat catttcctaa
    13681 agaatctccc aaagagtaat ttttcgtacc aattatttcg tattcttctt cactaagaat
    13741 aaaacgacgt tctacacgat ctttttcatt tctagatgga ttttcaatct tatctacttc
    13801 ttcaacgtgg cttcttttat aaataaatcc atgatcagcc gtaactataa aacgatagat
    13861 actgccatca ttatgcaagc gattaataag tcgggaaatt tcgcttatcg ctaaatcaca
    13921 ggcctcaaaa actcgatttt cattcgagtg atcacctgtt ctatccactt gatcgtgata
    13981 aatataaatg actgatttgc cattaaatac ttctcgtacc tcagccttat tcatcttaac
    14041 cacatcatca taatttaaag ctacagcatt tgcatctcgt tgctggagaa tcgcatttcg
    14101 attggataaa ccattcgttt ttttcccatc aatcagtact tctgttcctt cattgtaagt
    14161 tagttgattg tttggtaata aggcggcttt accgaattca gtaactgaag gtaatacaga
    14221 aagaaagcta gccatgtttg ttgaatactt cttttctcta actaacttac gttctaaatt
    14281 catccctaac tcatatcgaa aagcatctga aataataact acagttttaa cagagcgttt
    14341 cattacagct tgattataaa attttcgaat ggatggacga ttcttaaatt caaaagtttg
    14401 attccaaatt tgtcctgatt gatcaagaaa cttcgaataa tttgcttcaa ctaatcgata
    14461 caattggcca tatttttgct tttcttctat atgatcacta ttccaaataa atttccgata
    14521 atgcgtatca acccaataca tttccttctc atattgagtt agcaaattat ccatgttcat
    14581 cggcaagcac aatctgtttt tatccacaag ataataagca tgtttcaata attgatactc
    14641 ataaatataa tccgatgcga aatgcatttt ttcgcgctgc tttaaactat caaaaattgt
    14701 ttgtcctgca attttcgttg tagtgtcaga agcctttaat cgttctgcat aaaacattaa
    14761 tatttttgca tgaatctcag aaaatacgtc tgcttcaatt agatcatcaa tttctatact
    14821 gtctaataat ccatcaccat caatagcctg atatactttt ttagatagct gttcaaagct
    14881 ttccatgtaa cgtgtatcat tcataaactg atccatgaaa gtaataatgt ttgctttcaa
    14941 atgtagtatt tcaaatcctt tgaacttctt cggcatctct tgatcaattt gataataaaa
    15001 atagttcaaa taaagacaca tcgtcagctt ttccaatgtt ggctggctat ccgtaaagcc
    15061 aaatttcatt tgaataaatt cccaaaattt agctgttaac tgatacttat caagttccct
    15121 taaaggattc tccctacttt ctgtaaagct ttttagaact acacgcagta aatcatttaa
    15181 tcgaatactt ttcgatttca acaaaacagc cattatcatt aattcaatcg tttctgattt
    15241 attaattgtc atatgcgtac taaattcacc aaaacttctc atgcgatcct ttgcattaaa
    15301 gaaattacga tactgtttaa ctgtctgatg aaatctaagt ggaatagcca attcattcat
    15361 gataatcgct aagcggtctg cactaaattc ctctgaataa ttcaatacac tcaacaaatg
    15421 attatcttca tctttatcat cccaacgagg aaatggcgca tagattaaat agttagtttc
    15481 gggatcttca tattccaata aacgcttagt tttaaattgt gcgtcctttt ctaatcgata
    15541 gatttttgca ttttgaatga ccaatgagtc aatttcttca agaaaatcct gatttgaatc
    15601 aaaccaaaaa atgattttcc tacatccata attaggaaaa cgttgattta atttttcttc
    15661 aatttgttgc gtatttatat ctgtcatcaa tctcacctaa tcgttctctt tctatacccc
    15721 ttatattgac ataatttgga taatttcgca cgcaatttaa gaataaaaaa gaaagttgtt
    15781 agaaaacaac tttcttagat aactattttt ttggttcttt gacccctttt gcaaaaattt
    15841 ggaatttctc gccggtttta ggatcacgct gcaacttatc ataattgaca attacaccat
    15901 catctaagtc taattcaatt cgttttaatg ctaagtgacc caacttctcg tcatactcac
    15961 gaacttcttt taattgcttc tgaatcttta caatttcttt tgtcattgca tttctttctt
    16021 ttgggttatc acttgttgaa atttgttgct gacgcaattc gattcgattg tcatacgctt
    16081 tttgtagttc gtgtaggtat tcagtacgta cttttcctaa ttgatctggt gtatagcgat
    16141 gcaagtacat taacgcttta aagccatttt gttttcctga gtccaattgc caataaattg
    16201 gtcgattgga gtatgttttt aaatggtctt tgtaaaaatc ttgtacgaag taacgacgaa
    16261 taatttctcg acttgtccct ttgccaccta aagtgtcagc gataaactgg agattttctt
    16321 caagggtttc tttaccaaaa gtaatctcaa cgaaatcaat gaaacgattg acaatgtcaa
    16381 tttggctatc cttgaaatac tcatcatcgg tgatgagtaa aacattatca gtatcaggtt
    16441 taaatttttg atagcgggaa ggatcccatt cgccgccagc gaagatgaga ccatcttcgt
    16501 ctagggagta acgaccgaag atacaaccta ttgaataaga aataaaatcc ttaatttccc
    16561 tcgccttatc aggtaacctt gcagagatat attcatcttg aacctctttt gttaattctt
    16621 tttcaagaga ataatgatta atgaatatgt cgttcagttc ctcttcattc gattttagag
    16681 tattaaattg attaaccaac tgcctactta gacagttaaa tgcctctgag agatcttttt
    16741 taaacatata acttaacaaa atgtttcttc taaactcgta tgacgtttca agagcattat
    16801 agtcttttct agctatatcg atattttcat ccactttttc tcttattttt tttaattttc
    16861 tctcagatgt aactttaaga aaaggtagtt ttcccattgg tccttcatgg taatccaagg
    16921 tgggagaaat aaaagttaaa aagtgattaa ctaatttaga gtttacatag ccaaatattt
    16981 cttcaaagtc agttatatcc tttgagaaca gaacagatcc tttagtttca aaaattgcct
    17041 gattctgcaa tctaaaagat acttgtccag atgaaagtgt cgaccaagta attccctttt
    17101 taaaatagta attaagattt tgtggtctag attttaactt cccattttca ttaacataat
    17161 tttttatttc atctccatca ttctcccagt taaccacgta ttcattgttt ccataccatt
    17221 ttctaaaacg accaccttta gttgtaggaa accatttttt tctagacttt ttagcgtcct
    17281 ctaatgtttt agcatcaaac tttattttgt taaattctac ttcaaaccaa taccgcaaaa
    17341 atttattgtt atttccggtt gccaaccctt gttttgcatc tgcaacatcg ttagttaatt
    17401 ttccttgagc aaaatcagtg attacgttat cgcttgccca gtaagcaatc ggcattcctg
    17461 ggattttttt gaagttgtct tgattagtac tataaaaata atcgcattca ccatgctgat
    17521 gaattgcttc taacgtttta attttttgaa cttccattcc acctttaaaa tctgataatt
    17581 ttatatagct tccatcttgt tcatttgaat tttttatcgt aaacgtacaa attggaacgg
    17641 ttgcttcttc aaaagctgaa tactccattt gaatcaaact agaaatgttt ctttcattaa
    17701 ttaaaaatga gcgtaacttt tcatagctag aaatgaacat ccaaacaaat ggcgtcataa
    17761 aggaagcata tccattatca atcagcattt ggctattcaa tttaataaac acagaaaata
    17821 gatctttttt gacatcagaa tagttatcat ttacatattt ttttaatttc ttatccattt
    17881 tattaagata aggcggatta gtgactaccg ctacatattt atcaactagc atttcagcca
    17941 cgtcaagaat gtgcaagtat ttttcttgta tttccttcat cccataaaga atatccatat
    18001 tcgtaaattc gttgaatttt gatatatact ctcttacttt tcctaagtat tctttagtta
    18061 ttgcctgatt atttttatcg actaacttaa tgattgatcc aagttctttc ccattttcaa
    18121 attgatcaaa aattaactct ttgtattcat tccagcgttc actatactta tcattgttca
    18181 attcactaat acgctcttga tactcgtctg tcactttagg agaatcaata aactctctta
    18241 aattcggcga tagacttttt ttcaaaaaaa gacgatcgta ttgacgccct ttcatcataa
    18301 ttgcaaaata agacaattga tacgctcttt tatcgatttc aagaccatat aaattgtatt
    18361 caacgattgc acgtgcagca tcacgctcag aatatcctaa cgtaagataa atttccatca
    18421 atacatcgaa ggcgtaaact aaaatatgcc cagaccccat tgcgttatcg ataattttta
    18481 gttcttctgg ttttaaatta cttacagatg ttgcttgttc aaaagcatat ttatctggaa
    18541 ttaagtattt caacttattt cttaattcac tattgggata atgatctaac caatactttc
    18601 ctaaactatt gtcaaccata taacgaacga cccaatctgt ggtaaatagt tgagttgctg
    18661 ccggaatatc ttgttttttg acaatccctt tataaatatt caccacttga ttatgtggct
    18721 cactattata gtactgatac aaccacccaa taatctctac ctgtccacca gcttgaacat
    18781 agaaatcatc ctctggaata cttaaaagat cagcgattac accatctttt ttaatataag
    18841 aagctgtaaa caaaagttct gtataatctt ctacttcttc aaatagctca ggtaagtaat
    18901 cattcaattg attacagatt tttataaaaa tcaattgata cagcttgtcc attgcttctg
    18961 ctgaattatc tgttttccaa gttctgactt gttgctgttc attactagat aattcttcaa
    19021 agatatcggc atcataaata tctgtaataa tatctggctc aattttccca cttatttcac
    19081 tagataatac acgatacgtg tcaggtaaat aatcatttac ctccataaac cgaatggcaa
    19141 tcaatcggtt aaaccacgta taagcaacct cttcgattaa ctcttgaaaa gcttctgaat
    19201 aagaagtgac agaagcacgt tgttttagtt ctgcaatcaa tttgtttctt tgcgctattt
    19261 cttttccttg aattcttatt cctgattttt cgatttcttg taaattgcta tcaattttct
    19321 tcacatcttc aatttttgat tcatcaattc ctaaacgttt tgctttagtc attacttcat
    19381 caattaattt tctacgggca ttgaccgcga aattctttat cgctttctta tccatttttc
    19441 tttcccttct atatgtaacc tttgaaaaga caggcacctt tttatgcctg tcttttcact
    19501 agaattgaat cgtgatttct gtattttctt gaagttgttc cttcagtttt tgattaattt
    19561 cagctgttaa ctcatcaata tctgctgctg acttaatagt tttaacatga acgttaagtg
    19621 ttctcattgg tactgttttc tgttgaatag taggttttac tatcgctatt tcttcagctt
    19681 ttgctgcaga gtctatttca tctttttcag tttcacgaat caagtttgct gcttcaattt
    19741 gtttacgtgc ttgttcttct tgacgtctgc ggttttcttc attatcgaaa cgttgattaa
    19801 agatcaaata ctgttctgct acgtttaatg ataagaaaac aagatcatct atagtattcg
    19861 cttgttcaat ttttgctttc agttcttgaa attcttggtc aactattggt acaaattgat
    19921 ccttaaaatc ttttccttct aataatttaa atgttgcttg tttttcttcc gttaatttat
    19981 ttaatatttc ctgactttcc aactctaaca gttgattata ttgttcaata aattcttgaa
    20041 tcaactcatt tagtttcatc atatctgaat aaggatcagc ctttttcaaa atggttttca
    20101 tctcatgaat caattgatca atttcttggc tagaagtttg acgccgactt ttttcgatta
    20161 atctaatttt atcttgtgca ttctcccaga tttttttctg agtactattt tgcttgtgga
    20221 aatttttaat tttatcatat gtttcagccc agtcgaataa ttcatcgcga tattttttga
    20281 ttgtataaaa aaagtcttca acatctgacg tttgaacaat tacttcaaga tattttttta
    20341 tttgctcata ttcataagca ctagggtagg tataagtgtt ttgtaaatca aaataagagc
    20401 gtaaattgtc taattgacct tttaaatatt tcttgaaatt ttccattgta tgttcattgt
    20461 tattttcatc aacaatatta cgactttgaa acagttctct accgatttcg tcaaccaatt
    20521 tttttgcttt tggcgaaatc accgcgcttg gttcaatttt tatcttttca ctttctcgtc
    20581 gtttttgaat aatcattaca atactatttg gatcatccat ccgtgaaatt tgtacattgt
    20641 tataaagtaa atcaatttta ccagacatga aaagtttagc gatgcaccat tccacatcaa
    20701 gttctgtgaa tccatacggt tgttttgttt caaaacgatc acgaattgtt ttcatcgtaa
    20761 tcgttaggtg atttctcttt tgatcattga taaaattgaa aatttcctga actgcttgct
    20821 catttgatgg atcttcaata atttcatttt tgctttcttt cactaaatat aagatatctt
    20881 ctttttcttt aggcgcatca atttggttta atttatggta tacttcttca gccattttct
    20941 gaagtgctga ttggaatttt gctttaaagt cggagcctgt cagttgaatt tctgcaccgt
    21001 tatagaaaaa ttttgcagat ttcaacagtt catttaattg atcgttgata cttgcactta
    21061 gttcctgtaa ttcaccagat ttttccgaac gaatcgcgtc aaagttcttt actacactcg
    21121 aataagtcgt tgttaaataa agattcattc tagcatacat tgctatatca tctttaaatt
    21181 ctttatctga tggcaattct acgaataata agttacggga actcttaagc gcaagttctg
    21241 cctcttgacc tgctaaatca gagtatggtg aaataaaatt aactgtcatt tcagcatttc
    21301 cagcttgctt gtatggacgt tgatctaaca cttgtgcata agtaaacgta taccggtttt
    21361 taaatttatt tccacctgac atgcctaatt tttcataggc aaaactattt cggtctagaa
    21421 cgccgtcaaa aattcgttta gatagttcta cgatcaaatc actatctgta atattttgat
    21481 ttttaatctc acgagtaatt tcctgttctt catcagtttg gaaaatataa ctatctaagt
    21541 tcttccgcac aaagttttcc ttaattaaaa ggtccaatgc ttcttctact cgttttttag
    21601 tttccaggcg gtcttcgttg atatttctta tcatcaagct cgtaatattt tcaacatttg
    21661 gtttgatggc ttgatcaaca tatttaatca tgaataaaat tcgtaagaca tttacgttaa
    21721 agttatctat atcagttggt ctttgaatat gagaattatt tgtagcttgt gtaatcactc
    21781 ggctaattgc tgtatcaatc caacgttcta acgagtaata aaactgatct aaagaaacca
    21841 aactggttgt atcattttcc ttatttcgtt cagcggcttc tttaaacatt gctagtaatg
    21901 aacgttcacc agacgataag tttgatcctt gatagctgtg attacgaatc tcggttagaa
    21961 tttgccccaa taaattgaat tgatagggaa taaatggata aacttctgcg taattttcag
    22021 catcttggaa gagctttaat tcaggactat caacaaagag taatttattt ttcaattctg
    22081 tttgaacagt ttcaaattgt aaggctaaag aatcattggc aaactctttt ttcttcaaaa
    22141 tacgttcttt aattacttca tcggcatttg ctgaagataa actcacagtt gtggcaaaac
    22201 gatccttgat cttagaaaaa tcattatcag aattgttatc aaagtttgtt acgtgatcaa
    22261 tcgcttcctg acttgtcact aatacccaag ccttaccttc acaaattcga cccaaatctt
    22321 ccacaacggt ttgtaactgc aaagtcaact cacgattacc gccgatatat tgtccgacct
    22381 catcgactag aaaggcaata tgatggtctg cttctttgga atcaagatag cttttaacta
    22441 gatttgcaaa gtcatcaatg cttattaaat aatttcctga tgctttttct aaaaaattat
    22501 caatagcggc ttcactcata aaatcgattt taagtgccgc ttctttgata tcatcttgga
    22561 tccaatcaaa ctcatggcgc tcttcttgcc attttgcccc attaatctct tcaaaagcag
    22621 ctttgaatgc atcaaacttt tcttctttaa ttaaccgacg ttcaaaatct gctagatgtg
    22681 gaatcgtgct taatccttgc atttcgttaa atacctttaa aaaaacattc acgattccgt
    22741 ttttgtcttt tttaccacct gcatcacttt ttgaatcaat attaaacaga ataacatctg
    22801 tatttatttg tgagcaccgt tccatcgttg ccaaagtcag tggatctttg attttcccat
    22861 cttctttgaa gtaatcaatg gctttcttgt catttatttc tcgatttgcg agcaagtaag
    22921 aaataatttt taagaaatga gatttacctg aaccaaagaa cccctgaatc caaacaccca
    22981 ttttatctgt tggtgtattg atactccgtt ggtaggcatc aaaaattgtt ttaaagtgtt
    23041 tttgtagttc tttcgtaacc acgtattctt ctaattcttg ttgaacattt tcatcctttg
    23101 cttgaccgac cttaataact ccttgaatat ttcggtcaat tggttttgca aaaatatctt
    23161 taattagcat ttaatctcct accttccatc ccaactaaat tctaaatgct cgataataat
    23221 tatcatcttt attggtatta agaattgtca aacttaattc atcatattcc cctggataca
    23281 tcatcacaac tggtacgcga tcaaatacct gatgcatttt atttaaaata gagtgcgctc
    23341 taattaatgg atataattcg ccaattcctg tcaggaacac aactgatttt tctggtgtat
    23401 gggcatccac atattcaaaa aatacatttt cttcctcagg taaatccatt ttcaataaac
    23461 gaccaatgct ttccactaat ttttgtaaac cacgtcgttc ttccatctta atcgcttttt
    23521 cagtgaaacc gcgtttttct agatactcta acataatcac atagagatta taaactttca
    23581 cttcataatt atcaccaaca gatgttccag atatatcatt aatataatct cttacaatta
    23641 actcgtcttt cggatcgtag tcaaagatat aatagcctac ttcattacct aaaccacgat
    23701 tcaataaaaa atcttctttt tgaattactt cattcaactt ttccaaatgc tcttgaatcg
    23761 ataatgacat tataaaattc ctcccagtgc tagtacaata tctttacgat tcttgtcaac
    23821 taaccattga atcaatcgtt tatctaataa tatcggagtc attcgtccat attctttttc
    23881 ccctctgact aatcctgttt caattagatt cgtttgataa gcggcaataa gccgtttaat
    23941 cgtataatct ttccattttg aaatatcttc tgaacttctc cgcttctctg taaaaaaaga
    24001 acggtaatca actggtgtta attgcaaatt tcctttacgt agattttcag catatacctc
    24061 agtcataaat tcattaaaaa gatcatcaat cataaggatg gaaatcaaat tcactaactt
    24121 ttgattatct atatttaact gattgaaaag ttgcaatcca gcttcatcca gttgactaac
    24181 tctccttttc acgttctgat agatttcttt ttgacggtta ctgctcactg caaaaaaaat
    24241 attttcatgt tcatttttct ctttaatttc tatatctgta tatccttcta gtcgtaattg
    24301 aatatataac ttgaactctg aaaaccaaaa gcgtttagaa actagaccag cagaatattt
    24361 tttattcaat agattgcctc ctaatcatct ataattcaat aagtaaacaa gtgttttttg
    24421 ctcatcgtta gcattcattt tttagtatct actatacaat acatatttat tatagt
//
LOCUS       DAYYEF010000041        24433 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000041 DAYYEF010000000
VERSION     DAYYEF010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.042"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(45..1340)
                     /gene="purB"
                     /locus_tag="ACHA1B_001887"
     CDS             complement(45..1340)
                     /gene="purB"
                     /locus_tag="ACHA1B_001887"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004018 - N6-(1,2-dicarboxyethyl)AMP
                     AMP-lyase (fumarate-forming) activity [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HFM8702646.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1353..2477)
                     /gene="purK"
                     /locus_tag="ACHA1B_001888"
     CDS             complement(1353..2477)
                     /gene="purK"
                     /locus_tag="ACHA1B_001888"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HFM8702647.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2470..2958)
                     /gene="purE"
                     /locus_tag="ACHA1B_001889"
     CDS             complement(2470..2958)
                     /gene="purE"
                     /locus_tag="ACHA1B_001889"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009320 - phosphoribosylaminoimidazole
                     carboxylase complex [Evidence IEA];
                     GO_function: GO:0004638 - phosphoribosylaminoimidazole
                     carboxylase activity [Evidence IEA];
                     GO_process: GO:0006189 - 'de novo' IMP biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0009152 - purine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HFM8702648.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3374..4681)
                     /locus_tag="ACHA1B_001890"
     CDS             complement(3374..4681)
                     /locus_tag="ACHA1B_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="HFM8702649.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4684..5265)
                     /locus_tag="ACHA1B_001891"
     CDS             complement(4684..5265)
                     /locus_tag="ACHA1B_001891"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016763 - pentosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0043101 - purine-containing compound
                     salvage [Evidence IEA];
                     GO_process: GO:0046110 - xanthine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HFM8702650.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5381..5478)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5837..7129)
                     /locus_tag="ACHA1B_001892"
     CDS             complement(5837..7129)
                     /locus_tag="ACHA1B_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFM8702651.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7126..7749)
                     /locus_tag="ACHA1B_001893"
     CDS             complement(7126..7749)
                     /locus_tag="ACHA1B_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702652.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7752..8588)
                     /locus_tag="ACHA1B_001894"
     CDS             complement(7752..8588)
                     /locus_tag="ACHA1B_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702653.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8605..9492)
                     /locus_tag="ACHA1B_001895"
     CDS             complement(8605..9492)
                     /locus_tag="ACHA1B_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702654.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9508..10791)
                     /locus_tag="ACHA1B_001896"
     CDS             complement(9508..10791)
                     /locus_tag="ACHA1B_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8702655.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            complement(11474..12157)
                     /locus_tag="ACHA1B_001897"
     CDS             complement(11474..12157)
                     /locus_tag="ACHA1B_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFM8702656.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(12175..12792)
                     /locus_tag="ACHA1B_001898"
     CDS             complement(12175..12792)
                     /locus_tag="ACHA1B_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFM8702657.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(12802..13626)
                     /locus_tag="ACHA1B_001899"
     CDS             complement(12802..13626)
                     /locus_tag="ACHA1B_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HFM8702658.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(13619..14179)
                     /locus_tag="ACHA1B_001900"
     CDS             complement(13619..14179)
                     /locus_tag="ACHA1B_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702659.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14353..15309
                     /locus_tag="ACHA1B_001901"
     CDS             14353..15309
                     /locus_tag="ACHA1B_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HFM8702660.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(15614..16570)
                     /locus_tag="ACHA1B_001902"
     CDS             complement(15614..16570)
                     /locus_tag="ACHA1B_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HFM8702661.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            16674..17276
                     /locus_tag="ACHA1B_001903"
     CDS             16674..17276
                     /locus_tag="ACHA1B_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HFM8702662.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(17364..18863)
                     /locus_tag="ACHA1B_001904"
     CDS             complement(17364..18863)
                     /locus_tag="ACHA1B_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HFM8702663.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(18879..19403)
                     /locus_tag="ACHA1B_001905"
     CDS             complement(18879..19403)
                     /locus_tag="ACHA1B_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HFM8702664.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            19701..20450
                     /locus_tag="ACHA1B_001906"
     CDS             19701..20450
                     /locus_tag="ACHA1B_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HFM8702665.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            20441..21226
                     /locus_tag="ACHA1B_001907"
     CDS             20441..21226
                     /locus_tag="ACHA1B_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM8702666.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            21195..21911
                     /locus_tag="ACHA1B_001908"
     CDS             21195..21911
                     /locus_tag="ACHA1B_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFM8702667.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(22013..23032)
                     /locus_tag="ACHA1B_001909"
     CDS             complement(22013..23032)
                     /locus_tag="ACHA1B_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase"
                     /protein_id="HFM8702668.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(23051..24052)
                     /locus_tag="ACHA1B_001910"
     CDS             complement(23051..24052)
                     /locus_tag="ACHA1B_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HFM8702669.1"
                     /translation="MTSTVFIILLGFVCRKKGIFSESVGKILSKVVLTVALPALAFRA
                     FMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYKGDKQTTLRVLTIFGSTTFF
                     GTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGLKMEAKNIKAMFVNPIIIAT
                     FAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPWLFQPMDYLAGLSSPLAWLA
                     IGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILAVLTATNILPVNFEALATIV
                     IMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVLTPVWIVVLQMIHGIGLFS"
BASE COUNT         7252 a         5248 c         4252 g         7681 t
ORIGIN      
        1 tttttgctat tctattttaa ttgaattttg caactcactc ttctttattc caaacctact
       61 cgtttgaata tcacgtcaac gtttttcaaa tgatgatgat aatcaaaggc atcgtctatt
      121 tcttctttag ataataccga tgtgatggtt ggatcttctt ctaacagcgg gcggaactgc
      181 acttggttgt cccaagcgta cgcagttttt ggctgaacaa gatcataagc ttcttctctt
      241 gtcattccct tatcgatcaa tttcagcata acgcgctggc tataaatcaa accaaatgtt
      301 gcagacatat tccgcttcat gttttcagga aagaccgtta gatttttaac gatattgcca
      361 aaacgattta acatgtaatt caataaaatc gtggtatcag gcaagatgat tcgttctgct
      421 gaagaatgag aaatatctct ttcatgccat aatgtgacat tttcataggc agtgaccatg
      481 tgtccgcgca ccactctggc tagaccagcc atattttctg aaccgatcgg attccttttg
      541 tgcggcatag cagaagaacc tttttgacct ttcgcaaaaa attcttctac ttcacgtgtt
      601 tcggattttt gcaatccgcg tatctctgtt gcaaaacgtt caatacttgt agcaataagc
      661 gccatcgctg agaaatattc agcatgtaga tcccgaggga gaacttgagt agagatttct
      721 tgtggacgga tccccaattg tttacataca tactcttcaa taaatggcgg gatatttgcg
      781 aacgttccca ctgctcctga gatttttcct gcttctactc cttttgccgc atgttcaaat
      841 cgttcgatgt tccgtttcat ttctgaatac catgtggcaa gtttcaatcc aaaagtagtt
      901 ggttcagcat ggacaccgtg tgtccgaccc atcatcactg tatatttgtg ttcttttgct
      961 ttttcgccaa tgatttccgt aaaacgtttc aagtcttccc gtaaaatatc atttgcttgc
     1021 ttgatgagat agccataagc agtatctacg acatccgtac ttgttagacc ataatggacc
     1081 cattttcttt cttctcccaa tgtttcagaa accgctcgtg taaacgcaac gacatcatgg
     1141 cgtgttaatt tttcgatttc caagatccga tcgatatcaa atgatgcatg ctcacgaatt
     1201 tttttcacat cttcttgcgg gatttcacca agttctgccc aagcttcatc tgctaaaatc
     1261 tcgacttcga gccacgcacg gtatttgttc tcttccgtcc agatattccc catttcaggg
     1321 cgtgtataac gttctaacat gttttttctc ctctaatccc aaatattcgt ttgtttgatt
     1381 tcttccagcg tttgctggat gtcttctgtc aagatagtga tatgtcccat cttgcgacct
     1441 ttttttgctt gtttttttcc atagaaatgg aattgccagt ctggcttatt ctcaatcaag
     1501 cgatagcttt ccagcagttg ttctcccaaa acattgacca ttactgcatt gcttatcaaa
     1561 cgtacttttt ctcctaatgg ccaaccacaa atacctcgaa tatgggcatc gaactgactc
     1621 atagaacaag cttcaataga ataatgtcca gaattgtgag gacgaggagc taattcattc
     1681 acatatagcc cgcctgtttt tgttaaaaac atttctaccc ctaaaacacc tgaaaggctc
     1741 actgcttctg caatcacacg ggcaatacgc tcagcctcct cgatcacatc ctgatcaatc
     1801 gcggctggag caatcgtttc atgaagaata ttgttgtggt ggatgttttc cacgaccgga
     1861 aaagtcgtga aatctccttg accatttcct gccaccatga tcgaaatctc tttttcaaac
     1921 gggatccatg cttctaaaac acaggttcct tctcttaaaa ggtccatggc aggagctaga
     1981 tccgcccgac ttttcaaaac atactgcccc ttgccatcat agccgcctcg agtggttttc
     2041 aaaacacaag gatagccgat cccgtcaatc gcatcttgga tatccgtcgg actgacgatc
     2101 gttgcataag gagcaatcac gatgttattc gtttccaaaa aagatttttc taacaggcgg
     2161 tcttgcgtaa tcgcaagcaa gtctgtccct tgaggaataa atgacatggg taaaatcgca
     2221 tttaacgcct ctacactgac gttttcgaat tcataggtaa tgacatctgt tcttctggca
     2281 agctctttca gcgcaaaggt gtcatcatag acactttcaa tgtgccaatc tgcaacttgt
     2341 gcggctggac aatcgctcac aggatccagc acacctactt taaagcccat ttcttttgca
     2401 ctaatcgcca tcatacgacc taattgaccg ccaccgacga tcccgatcgt tgaaccaggc
     2461 aacaaaggtt taaccaagtt gatcactact ttctataaca gttttagcca acattgaacg
     2521 tctttcagcc aatttagcct ccaattctaa atcatacatg gaaagcatct gtatcgcaag
     2581 tagtccagca ttaattgctc ccgcttttcc gattgctgta gtagctacag gtactcctcc
     2641 aggcatttgg acaatcgaaa gaagcgaatc caaaccattt aatgttcgtg attggaccgg
     2701 tacaccgata accggcaaag ttgtttttga tgcgaccata cccggcagat gcgcggctcc
     2761 ccctgctcct gcaataatga ttttgattcc tttttttcga gcgttttgtg catattcaaa
     2821 catcaaatct ggggttcgat gagcagaaac gacctttttt tcataagaca caccgaattc
     2881 atccaatatt tgacatgctt ctttcattgt ttcccaatct gaagtactcc ccataatcac
     2941 agagattttt gctgtcattg tttttcctcc cagtttttct acattcatat tttaacaatc
     3001 actttttttg atgtcaaaga aatttcgaat gttaacaaag aaaaacattt tattgttcgt
     3061 gtttattaaa gataaaaaaa aggaatgtga caaaagttag gtcacattcc tttttatgga
     3121 taaacggtgt tctcctgcca actcctcggt cacaaggaac aatattcaac aaacatgaga
     3181 agcttttttt tgaaattgtt ccttgtgact cggagatgaa cggcaggctc acgacctctt
     3241 ccttcaacgg tgttcaatca gctgaccctc ggtattagct caaacaaacg gcaaaatacg
     3301 aggaactatt tttccgtttg tttctctaac aatcaggtca aaacgctgat ttcacaacct
     3361 ttcttttgct ctattacttc ttgaaggctt cttccaatat ttcttcatct tttttcaatc
     3421 cattaaagat caaattcaat atgatagccg taatgctact cattacgatg ccatttccag
     3481 tgaacatttg caatgtttgc ggcatttgac tgaataatgt cggcgtaaca ttgaaaccca
     3541 gcccaaatcc aacagaaaca gcaacaatca atagattttt atcattgctg aaatcaactt
     3601 ccaacagcat acggattcct tggactgcca ccatcccgaa catgactaac attcctccac
     3661 caagtaccgg ctcagggatg atttgtgcta acgcaccgat tttagggaat aatcctaaaa
     3721 caatcaagaa gaatgcagag aaatagatgg gttttcttgt tttgattccc gaaagttgaa
     3781 ccaatccgac attttgagaa aagccagtat aagggaatgt attgaaaata ccgcctaaga
     3841 taacggcaag tccttctgca cgatatccct ttttcaattc ttcttctcca acatttttcc
     3901 cagtaatgtc accaagtgca aaatatacac ctgttgattc taccatgctg accatggaaa
     3961 tgatgatcat tagtaaaatc gaccatacgt cgaaagttgg tttaccaaaa taaaagggtt
     4021 gtggaacatg gaacaacggc gcatctccaa tcgcgctcag atcaatcatt cccatgaaag
     4081 cagctaagat gcttcctccg actaaaccaa tcaataccgc gattgaacga atgaaccctt
     4141 ttgccagcat ttgcacgcct acaattagga gaatcgtcac aaatgcaagt agcagatttg
     4201 ttttgtcacc aaaatcagct gctgttgcat tacctccacc cattttctcg attgctacag
     4261 gaatcaaagt caaaccaata acggtgataa ccgttcctgt tactatagga gggaatagtt
     4321 ttttaatttt agaaaagaca ccagaaacta acacaacaaa gatcccagaa gcgataatag
     4381 atccgtagat agctcctact ccttcattgg ttccgatcaa gatcagtgga gctactgctt
     4441 ggatcgcaca tcctaaaacg acaggcaagc caattccgaa aaatcggtta actgtcaatt
     4501 gcaataatgt cgctaatcca cacataaaga tatcaattga aatcaaataa gtcatctgtt
     4561 cttgattaaa gcctagtcct gtaccgatca aaagaggcac cgctactgct cctgcataca
     4621 tcgctagcag atgctgcagc cctaaaaccg cagcttttcc attttgtgtt tctttttcca
     4681 cgattatgcg tcctcctcaa gaaactcaac ttgtccattc gtcaaggaag caatacgcgc
     4741 aagagaaacg actctcaatc ccatttcttc aagtaactga cgtccatctt ggaaagactt
     4801 ttcgatgacg atcccgattc cttctacttg cgctccagct tgctggcata attcgatcaa
     4861 tccttttgcc gcttgtccgt ttgccaagaa atcgtcgata atcaatactt tgtcttctga
     4921 agataaaaat ttacgagaaa tagaaatcgt acttgtcact tgtttcgtaa aagaataaac
     4981 agaagctgtc aataattctt catccatcgt caaacttttt gcttttctag cgaagatcat
     5041 tggaacatct aattctcttg cagcaaataa agctggtgcg atcccagaag cttcaatggt
     5101 cacaactttc gtgattcctt gttctttaaa tacttctgca aaccgttttc ccatttgttc
     5161 catcaataca gggtctactt ggtgagtgac gaagctgtcg acttttaata cgccctcgcc
     5221 taatatacgt ccgtcttttt gaatacgttc aactaattct ttcactttat ttgctccttt
     5281 atcatttatt aataccgaaa taaccgcttt tgtgcaaaaa cctactatgt ttctgttaaa
     5341 gaaaaacacc ctccacttta tcataagaaa agaagggtga aatagccaat cttttactta
     5401 tagtccagca tttacggtac tggctagaaa ctgtcatcca tattatgacg atatataagt
     5461 aggtatgtaa aactaataat agtgtaaatt cattttcttg caactgtttt gcacgtgaag
     5521 gcagtttgcc atatttgaat aaaaaatgtt gtttcaaata ttgaaaacag tctaacacta
     5581 ctttctgaaa ctgacaacgt ggtttactta tttttttgta aaatctaatg atttttaatg
     5641 cattattcct ttttgttcgg gtttaaatag ttatttttat tttctcctat ctaaaaaagc
     5701 agcccacata aaaagaaggc atgacaaaaa gcatgtcata gccccttttt ccgaataaat
     5761 agtgttcaaa agacagccta tcggcaataa ggcaagattt tataaactac gggaagtaat
     5821 ttccgtaaat ctattcttat tcttttaagc tgacaagctc gtcaatcact actgcttttc
     5881 ctgaagcaat agaatgattt gctgcgattc ctgtcaaaat cgacaaaata ccatctacgt
     5941 gagttgctgc ccgattccac ggatcttctt ctttttcttc accaaataga tcatctaata
     6001 aacgcggatc tcctccgcca tgtccgcccg cttcttgttc gacgattacc tcatatggct
     6061 caccgaacat cggatagaca tggatggact gaagaacggc tgctccttca tcctttttat
     6121 ctccacctgc attgatgtaa gacttttcga tcactttcat ttcgatccgt cctttgctgc
     6181 cattgaaaga aacattgaat ccttcccacg gcatatacgc gtttagcgaa tacgtcaaaa
     6241 tcgcaccagt ttcatatttg accgttacgc ctagtgtatc ttcaatagag atatcatcgg
     6301 aaaatacact gcggtcacga atatatccac tgtctttttc tgcttctaaa tacatttctc
     6361 gcaattcctc attggctgac aggtctatag caaatggatc agctttagct agttcgcttc
     6421 catagcatcg actgtaaaat atttctactc cgcgtttctc cgcattatgc atcccataaa
     6481 agtttaatcc accgaatgca aatacctttt ggggacggct gttcaaccaa aaattcacta
     6541 gatcaaaatg atgggtagat ttatgaacaa gaagcccgcc gctattgtgc ttatttcgat
     6601 gccatcttct gaaataatct gccccgtgtt gcgtatttaa cagccattcg aagtggatag
     6661 aaaacacatc accaatcaca tcactttcta tcagttcctt tatcttcgtg tgatacggtg
     6721 cataacgata attaaaagtg actcgcaggc ttcttcccgt ctgtttttgg accgttatta
     6781 tttcttgagc tttttcctca tcgatagtca gaggtttttc gcaaataaca tcatatcctt
     6841 ttttcattgc acgaatgata taatcatgat gcgttcgatc tactgacgta ataatgactt
     6901 cagccggccg tacgtcatcc agtagttgct caaattgtga tggcatacat gtctttactt
     6961 ttttctgtcc atacttgttc acaagtatcc gatttgcata atccatcctt gtttgagata
     7021 catcacaaaa accgactagt tcacaagttt gatgatacgt agaggcaatt gcctcataaa
     7081 aaaaacgcgc tctcccacca agtccgactt gtacatattt tttcttcatt taaagtcatt
     7141 ctccttttct tttaagcaaa atactgtgac aaatggcagc cctggataca gtaatgcagt
     7201 gagtaaaaaa tcatgctgta tacaccagaa cagtccatac aaaaggcata aataccacag
     7261 aaaccccttg acgttttttg acaacagcca gatattcctt ttgatcaaat aaacaagact
     7321 atctgcttta tcttctttgc agatatcaat tagcgtacta aaaaaactat gggatacaaa
     7381 aagcaacaga cacaatagaa aaggaatcag ataccaagct ccaatctttc ccactaataa
     7441 ataccaatca actgcaaaaa taatgacaaa cagctgaaac aacgtaatga tgaaacacat
     7501 ccgtttgatt tttcctttcc tccaacatac ctttttttct gccaagtaat ggacagatag
     7561 ataataagaa ggatacatca tcaaaaaata aatcagatag acaacacgag cagacagcac
     7621 taatcctaaa gtgaacaaac atcctagaac taaagcgaaa agagcattac tgataagact
     7681 ggttaaaaaa atccgacaga catagtagtt gagcttgtaa agaaacatct cttctattgg
     7741 ctttttcata ttcagccctt cagaccgctt gtactgatcc cctggacaag atatttattg
     7801 aagaataaga aaatcagaaa aaccggtagc agcgacaacg tagacatcgc aaacatactc
     7861 gcgtaagtcg tactagatcc agcgtctgca aataatttga tggcaatcga taccgtgtaa
     7921 gatctcggct tgtttaaata aatcaatggt cccatgaagt cgtcccattt ccaataaaac
     7981 tggatgatga tcgtcgtgat gatcgaaggt ttcagcaaag gaaaaataat tttggtaaag
     8041 acactatact tgctgcatcc gtcaataatc gctgattcat ctaactcttt ggggatgctg
     8101 accatgaatt gcatgatctg gtaaatgaaa aatgcttgtc caaaaaaatg tggtaaaatc
     8161 agcggcacat acgtcccaac caaattcagc cgattgtaaa taataaactg cggaatcaaa
     8221 atcacttgtg caggaatcat catcgttact aacatgacga cgaaccagaa tctttttcct
     8281 ttgaaatcga ttctcgataa tgcgtaagca atacaagtcg agctcagaac tgtccctatc
     8341 gtcgaaactg cagagatgac aaacgaattc ctaaagaaag taaaaaatga aattccagca
     8401 aaccccgccc atccttttgc gtaattttcc cattgaaaag tctctggaat caaattcagc
     8461 gaaccactca taatctcttg atccgtttta aaagaacctg cgatcatcca taagaccgga
     8521 taaatcatga ctagacctaa tagcaaaata aaaccgtatt gaaaccattt cgttactgta
     8581 ttattcattt cttcctcctc tcattcacac aacgacccat ttttttgatg atttgaaaat
     8641 cagaaaggtg acagctccca taatcaacag catgatccac gaaatagcac tagcataccc
     8701 catagaatta aaagaaaaag cttggttata cacataaaga gcataaaagt tcgtggcatc
     8761 attcggacca ccttgggtaa tgataaatgc ctgcgtaaaa gtcataaacg ccgcgattgt
     8821 ctgcataacc aagttataca aaatgatcgg cgaaagaaga ggtaacgtga tcttgtaaaa
     8881 cgtctgccat ttgttcgctc catcgatctc tgccgcttca taatacgagc ctgggatctc
     8941 tttgatacct gcagcaaaga tgatcattgc cgaaccgaat tgccaagcag acatcaaaac
     9001 aagagggatc atgaccagtt tttgatcgct aaaccaggaa agcgcaggtg cgcctaatcg
     9061 ttccaggaaa atattcacta acccgttttt agaaaacaac tcccgccaaa ctagagcgat
     9121 agaaatactg ccaccgatca aactaggcac ataatacaaa gaacgaaaga aagtcgttcc
     9181 tttgatattc ctcgttaaaa gataagcaat caatagacca aagatcagtt tcacaggtac
     9241 agatgcaaat acatagagaa aagtgactcg gatggagttc aaaaaacggg catcactcag
     9301 catctttata taattatcca agccgatcca tgagactgga tttcccaaac gataatcggt
     9361 gaacgaataa taaagtgaca agatcatcgg tatcactgtt atcaatagaa atcctaggat
     9421 gaatggagaa gcaaatacgt aaccgaccac attgtcttga tccaagaacc gttttagttt
     9481 ttcttttttc atgccttcct cctgctgcta tcctagaatg tttgacgcaa actcataaag
     9541 actctctgct gcttcttctg ctgttacttc ttcataaatg actttttcaa ctaaaagatt
     9601 gtattggtct tgaatttccg gattcaaagc actatcaaag acattcactt cgccgttgtc
     9661 catatcggaa atcatttcta aataatcaaa tgtcgcttgc aaagttgcat catctgcacg
     9721 agcgagctgt tctcgaatat tcgacatgat tggtacacca cgttctcctt ttaaaatttc
     9781 attggcttct tcactgtttt gaaagaaatc aataaactta gcagcttctt ctttatgggc
     9841 tgagcttttt gccatactca gcatttgcga agaacgtaaa gggataccag attctccatc
     9901 tgcttttctg cgaggtggat taatcaactg aatctccata tcttcaggag cccctgacaa
     9961 tatttctgtc aactggttac ttgatagaaa caccattgcc gcttctctat ccctaaccgc
    10021 ctgaaaagac agatccgtcg tacttgcagc tccaccacct ggttctggat gggccccttt
    10081 gtctaccaga tttttacgca gctggaaaaa atctgttaga tagtctggat tttcaaatcc
    10141 caagctgtta gatagatctt cccgattata aaaattcaat cctttctcaa cttgtggtat
    10201 ttgaataata cagccagcta taaaatcttc gaatcttgaa atagcataga ttcctaattc
    10261 ttcagtgatt tgatagctga tttgttcaaa ttcatcccat gtccaatttg aagctggttc
    10321 agggatattt aattgttcaa atatattttt attgtaagca atcgcaaacg aattcacccc
    10381 gttagacagt ccaactaatt gcccgtcgta agtcgtcgtt gctaaatagg attcatctgc
    10441 attagaaata tcaattatcc cttgctccac atattcatct aatggttcaa tctgattgat
    10501 gtattgagga aattgattgt tcagttggaa aatgtcccag atatcatctg atgctgctag
    10561 tgtacctaat tttgtgtaat atccttcata atcataaaat tcataatcga tcgtcacatg
    10621 gggatttttt tcttcataaa gctcgattac ttttactgtt gcatcgtgtc ggacttgcga
    10681 accccaccaa gccatgttca gcgtgatttt tttgtcatct tcttgcccac aagccgtcaa
    10741 gaagaataac ataacactta aagctaagat gattctcatt cttttcttca ttctctgcac
    10801 ctctacttcc attgttattt ttcaatatac tgtattttta tacagaacat atttattaaa
    10861 cgatcttttt caaggggaat aaaaaccaag acttgcctta tcgttctgcc taggatgaac
    10921 aactcaatac tttcaagaaa aattagatag tgctgattct tctttcatcg ctaaaaacac
    10981 ttcttgcttc aatgatggga ggataattac gcaaagaaaa aaggatatca gacaactgcc
    11041 caatatcctt gacatagcta aataagcatg cttcttcgtg tgcgctcttc cctaaaaaac
    11101 agaaaaataa ctagtaattc tgtatgaaat taggtacaat atacacgtcg atgcacaagc
    11161 attgactatg gcaacttgat tggtcagttc ccgctgactt ttcaagcccc gacaatttag
    11221 ctgctactaa attgtcgggt gcctttttta gtttttattc gtttttcatt ctatagaaag
    11281 cgcttcaata aatcaagaca tttttttgtt agaatgctaa taataacaaa aggttttaac
    11341 tcttcttatg tacattacag gtaaaaaaac aaaaaaattt ctcttttttt tgaattctga
    11401 acaaatagta ctggagtaca aaagacgagg aagagccact atctgctctt cctcgtcttt
    11461 tgattctcac ctgttattca tgattctttt tctcagtttc ccgatatttt tccattttac
    11521 gactaaaaag ctctccgcta cttggtggcg tatatgtgat ggcatttgct cctgcttgaa
    11581 tggtctcagc aatactttct tccgttggac cacctgtcgc aatgatagga agttcaggat
    11641 attttttacg aaaatggcgt actgcttctg cagtttcttt acctgcactg atattgataa
    11701 tcgaaatacc agctgctaac ttttcatcta tttctgtata tttcgacgtt accgtactga
    11761 taactggaat atcaactact cgacaaactt cttttactgt ctctaaaggc gtaggaccgt
    11821 tcaaaacgac ccctaacgaa ccttgcgctt ctgcgaacat gctcatgtag gaagaacgag
    11881 caccttgtgt caaaccacca cctacaccgg agaaaactgg aatgtcagct gcctcaataa
    11941 tgcttttagt aatcgctgga tgaggtgtaa aaggatacac agcaattact gcattcgcat
    12001 ttgtattacg tatgatcgca atatccgtag taaagatgat cgaacggatc aattttccaa
    12061 atatcttgat cccgcttgct tctaaaatga tttccggtac tcttacgata tcttttctca
    12121 attccgtcat gatttctggc gtaaattgtt ctgccatcag ccacttctcc tttgctatct
    12181 ccggtcatac tgattcaatt gatacgtctc gatgacctgg atgatttttt gcgcataacc
    12241 ggggtctgtc gcataacctg catcttgcaa tgcttgtgcg gcttcctgat agttggtggc
    12301 cgtaatcact ttttcataca gcgcaggatt ccaatctact ccttggacga acagttgtgt
    12361 atggtcatcc atggactgtt cccatgaatc atacactttg aagtctcctt ggatagttat
    12421 ccattcttcg ttaacaaatt cctttgtttc caggcttact ttcttctgat ccccataagc
    12481 cttgatcccg aaaagattat tgtatttgct agccaaggta ctttttcccc aatttgattc
    12541 taatatagct tgtcctaaaa tgatactagg aagcactcca taaccatctt gtagttcttg
    12601 ggcatgcgga acaagccgtt caataaattg ctgatgggat tgcgcttcat tttcttgctg
    12661 attatcagta aaaggagaag acagattctt caaggaaaaa acaaaggcta agagtatcac
    12721 tgctacaccg gcaaccactg ctggccaacg gatattcttg cgcttttgct ttttccactt
    12781 ttttttcgcc atgatcaatt cctacttttc atttaattca ttcagatatt cttctagcgt
    12841 caattggtgt ttggtgatat actcagcgtt ttctttaccg acataacgta agtgccaagg
    12901 ttcatatgtg atcttagtta tatcttcgtg tccttttgga taacgaacga taaatccata
    12961 ctgcgcagca ttatctgcga tccatttagc tccaggctga tctccgtaac ttgcatccaa
    13021 tacagtagaa ggataactgt tgtaccagtt ttgatcgacg acatcgactg ccagacctgt
    13081 gtggtgttcg ctgtatcctg gctccgtaat cgtttcttta gtaatctttg tcgcctcctc
    13141 ttctgataca ccttgacgac tcatcacatc ttggacattt tgttcgaaaa cttgttgttg
    13201 ggatgataca gaccggtaag ctgagaccat cactaatgga aatccagctg cttcagcagc
    13261 cttggcaaat gcttcatatt ctggagcaat gcgtttgtcg atcaagtatc cgttacttaa
    13321 tgatgccaat tgagtagact catcaatttc tttttctaat ttgtgatctg gaccaaccaa
    13381 aactagcttc caatcgtctg ttttaacatc tggcaattgt ttggacgtac gatcttttgt
    13441 ttctttgtcc tttaccttgc tgctggttgt ttgactgttc ttttctttac tagcagttgt
    13501 tttggtgctt gttcgttcga ctgcttgatt gccggcttga acatgcgaat catcatcgct
    13561 aaaaataaca tagcccattg ctgcgatcat aatcacaact gctccaaatc ctaaaaattt
    13621 attcacttga aaaatccttt cgttgttctt cacgttcccc attcgcctca tgaacgtaag
    13681 tttcttccag attttcattc acccaatcga gaagttcgat tttttctcct tcgatctgtt
    13741 tttgaacatc tgctggcaga cgaaaattca aaatatcatc atagccccat tcatcatatt
    13801 gaatacttac tttcaagtca aggtatctac cagcctgctg attatttttc aaagggatca
    13861 gctcgacttt tgctgctttg ctgctaagcc atttttgcgc gatgcgtgtt ttgatttgct
    13921 tgtactctgc aacggcaacg tttcgttttt cgggaaaaat aatcgtttga cgcaaaatct
    13981 tttgcgttag catccattca taatcagtga aaagattttt tactttctgc atcgcttcag
    14041 atggcagatt tttctcgcca tctttccatt tttgccattg ttctggactg atcagcaagt
    14101 attcatctaa aaaatttttt tcagtttcaa actgttctaa taatacactc ataataagat
    14161 caatatatac ttgatgcacg tttatcccct ccttttaact attctactta agttttgatc
    14221 aaaaagcacc tcttaaatcg ctgctttcat tttttttaat gtttcaagtc ctctcctctt
    14281 tattcttcgt gatttttgtt ataataatag acagacaaga aactcaatcc aactatgaag
    14341 gagcgttttc agatgaaaaa atatcaatgg ggaatcgttg gtcttggtac catcgcacat
    14401 gagtttgccg aaagcttcaa tcaagagacg agcgaactaa cagcagttgc ttccagaact
    14461 tcagaaaaag cggaaaactt cgctcaccgt tacaatattc caaaagctta cggaagctat
    14521 caagaaatgt tagacgatgc tgaaatcgac atcgtgtaca ttgctgtacc aaatagacag
    14581 catatcgacc atatcttggc agcattggaa gcaggcaaac acgttctatg tgaaaaagcc
    14641 atcacgatga ataaaaaaga actggctgac gctatgcgct tagcagaaga aaagaatttg
    14701 atcttagcag aagcgatgac aatcttcaac atgccacttt atcagcagtt acgctcaata
    14761 atggatacag gaaaactggg ggctttaaaa atgatccaag cacctttcgg cagttacaaa
    14821 gaaccagacc ctaaaaaccg gttcttcaat ccagaattag ctggaggagc tctgttggat
    14881 atcggtacgt atgctgtatc tttcgctcgt ttctttttga gctctcaacc tgaagtagtt
    14941 gcctctacaa tggttccttt tgaaacaggc gtggacgaac aatccgtcac tatcttgcgt
    15001 aacaaagaaa atgaacttgc tgctgtcagc ttgacttttc aggcaaaaat gccaaaagtc
    15061 ggtatcgttg cctttgagaa cggttatgtg acgattgctg attacccgcg tgctgatcgt
    15121 gcggagatct tatttacaga tggtacaaag gaattcatcg aaagcgggaa tacatctgaa
    15181 gcaatgaatt acgaaataaa gaatatggta cacatgattg aaggtgactt gcccaatcgc
    15241 tctctcttct tgacaaaaga tgtcatcgaa atcttggatc aaatgcaagt tctatggaaa
    15301 aatatgtaat tttaaaaggt tgtgaaaaag ctgttctgca tcaagtaata agaacagcca
    15361 aacaaaaata gctcctccta tttttcgttt ggctggactt attaccgcag aggaaagctt
    15421 ttgaacaccg tttaagaaag aggttgtgag cctaccgttc agctccgagt cacaaggagc
    15481 aatttcaaaa aacagcttct catgtttgtt gaatattgtg acttgtgacc gaggagttga
    15541 caggagaaca ccgtttaaag aagaggttgt gaaatcagct ttttgacctg aatattagct
    15601 gaattcacaa cctctatttt tggatttttt gttgggagaa ttctgccttg atttcaataa
    15661 aacttttaaa agactgcaaa aactggaaca attctgctcg atcctcgaat tcagggcgac
    15721 tagtcggcag aggcatttgc cgatacaata cataaacttc ttcaatacgt gttaaaattt
    15781 gtctgccatc atttgactct gaaaatgttt ctgcagtata aatcaataaa ccatagatat
    15841 gttttccata ataagctggt tgctggattc tctctagatt ttccagcatg tctttaatca
    15901 cattggcctg tgctcttctc atagagaagt aagtttcgta gtatagcggc tgtctgagcc
    15961 agtagttttc ttgatgttct ctggcatctt cttggctttc gcgaatgaat gtcagtaaat
    16021 gttcgcattt gatctgcaca tcttctttat tttctgataa aagaaattct gccatttgtc
    16081 tcaaaatatt tcgaaattct ttttcgatct gtatttggtt ttccttcagc tgcttcgtac
    16141 gatctggcat gtaaacattt gcaagcaaag caaatactaa tccaatcgcc attaatcccg
    16201 cttcattgcc gatcagctgc caagacatgt tttcctccac taaataatga gtgaccaaaa
    16261 ccgaatttac tactatccct tcggttaatt tgaagcgaga ggcaagcggg atgaacagga
    16321 ataaaaaaag actgaagcca aaaatagtat acccaacagc aaaaaaactg aacagtgctg
    16381 ttgccgtagc taatataaag gctgcgattc gattcatgcc cgtacgcaat gtagagcgct
    16441 tggtatttcc tacacttaat aatgcaatga tccctgcagc tggccaatac aacagcgata
    16501 agctacccgc tgtgaccatc gaaaagaaga cactgatcac tgttttgact gttcgcattc
    16561 ctatacgcat ttacttcccc cttttttatt ttaattatac ttgaataatg aaaaactagc
    16621 tatcagacaa aagtttaggt atgatagtaa aaagaccaaa aaggagaatc tctatgcaat
    16681 ttggccgttt tcgactaggt atgcgtacga tcaaaagtgc cttagctgtt tttttatgta
    16741 tcttgttttt tcatttgact caacgaggaa tcccgatgat tgctgcatta tctgctgttt
    16801 tttctttgcg tcaggacttg actacaaccg tttcttttgg aaagtctagg atcatcggca
    16861 atacattagg tggtacatta gctatcattt atttttttgt caaaagctat tttcacaatg
    16921 attttttggt agaattgatc ttgcttccta ttctagttat tattgtgatc gtcgtgtcag
    16981 atggtattaa caataattcc ggtatcattt ccgcaatagc tacgttgttg ctgattgcgt
    17041 tgagcatccc tcaaggcgaa tccgctttgt atgctatcca acgtgtacta gatactttta
    17101 tagggacatt cattgcaatc ggtatcaatt tctttcttcg tcctcctgaa acagaaaaga
    17161 aggaagaact atcagaagat ttggtcgaac tccaaaagaa agaacgattg ctaagaacaa
    17221 atttacaaga gatagaagct aagatccaaa aacaaaagaa aaatagcgag gactaatttt
    17281 cttttgcaat aaaataaaaa aatggagaga agaactttaa aaagtcttcc tccatttttg
    17341 attgaacggt gaagtgtact actttattct tccttcatcg agttttgttc tgcctctttt
    17401 ggcgcttcat acatatttac ttggctagta gtcccacgtg tcgacaaatt ctctacgatt
    17461 tccttcaagt caagtcctgt tgtcgctttt agtgtttctt gagtagaaga aagcaaattt
    17521 gtggcataat ttgtcactcg gttcgctcca ctggtttctc ctgaactgct tcctgtatcg
    17581 acaacagaga ttttttcgat atttcctagc ggctgtgctg cttcgcgcat caattgcggt
    17641 agcatatcga taaccatact caagacagct gcttcgccat attccttgaa ggcattggcg
    17701 atcttttgtt ttgcttcggc ttctgctttt ccttttgcta gtgctgcttc ggcttctgct
    17761 tgtccagcta aacgtgtctt attggcttcc gcttctgcca gtgcttccac acggaatcgt
    17821 tctgcttcgg cttcagtcac ttctttgact ttttgagctt gtgcttcttg ttctttagcg
    17881 taccgatcgg catctgcttt tttcttcact tccgaatcat attgcttttc acgacgtgtg
    17941 atttcttttt cttccagttc gatttgtttt tgacgttcta cgattttaat ctgcatttcc
    18001 tgttcgatta cttgttgttg tgctcgggca ctttctaaat tgtaggcttg gtctgctttt
    18061 gctttagcaa catcttgttc ttgtttgtag gttgctaatt tcagttcttt ttcttttaat
    18121 gattctgcga tctctgtttg tcgctgtaat tcagctgctt gtgattcttt ttctgcttga
    18181 gcttttttga tacgcgtttc ttttagagct tccgcttctg ctatatctgc atctcttttg
    18241 acttgggcga ttcttggttt ccctaaagag tcaagataac cgtttttgtc tctgacctct
    18301 ttgatagtga aagaaacgat gatcaacccc atttttgcaa ggtctacaga agcgacttct
    18361 tgtacgcttt gactgaactt atcgcgattt tgatagattt cttctacagt catagaacca
    18421 agaatcgagc gcaagtgtcc ttctaatact tctcttgctt cattttccag ttcttctctt
    18481 gtcttgccta aaaactgttc tgctgctgta gcaatctctt ctacagatga accgattttg
    18541 atgatcgaag taccatcaca catcaccggt acgccttgtt ccgtatacac ttcaggggtg
    18601 gagacgtcca atttactcga taatagactg atccgattcg aacgttgaaa aactggcaag
    18661 acgaatgcgc cacctccacg cacaattttg attttgttat tgctttcatc aatgtgcaca
    18721 tttttgcttc ctaaataact tccactgatg atcaacgctt catccggttt tgctgtctgg
    18781 tacttcgcta caaagacgat cagcaacatc agtaaaatca aagctgcgat tgcgatcgcg
    18841 ataaaaacaa ctggtatttc catttaacac acgctccttt aagcttttat catgctttca
    18901 taaggcatga cataacagat tctttccttg atctcaatga tcaatacttt cgttccccgc
    18961 tcagctgtct gttcttgggg gctgtaaaaa caagctggac gactaatgga accggtaaca
    19021 cttttcaact gaatttctcc catacctcgt acagggatcg gtgtgatcac aacagctact
    19081 tgtccttcca gagttttttc agaagacgac atcgttgatt cggcatgttt catcggcatc
    19141 aatatataga aattaagcaa aaataccaac actatcgata tgcctccact agcaataaat
    19201 aaaaataaag atgattgatc tgttaaacgc tcacctagaa aaccaaataa gcttgtgaaa
    19261 gttaaccaag ggataataag catcggatca agcgggccat caaaatcgaa tacatctcca
    19321 aaaataatca ataggactgc caatcctgca caaatcagca atgtatacca ataaatcgtc
    19381 tcaagtgcga ttccccctat catatacacg cctccttcca tttctacgtc tatcatacca
    19441 atgtttgaaa attctgtata gcttctttta ccgactcagt ggtgtttttt ataggaaggt
    19501 tgtgtttatc gttgacaatt tgttaaattt ttgttttcat gttaaaattt tcacaataaa
    19561 ttctttcgag gtagcctatg tttccttttt ttaagaaaaa accattaaag ctccagaaca
    19621 cgatcatcct tgtcgtttgt ttctccacat tcgtttcttt gattgtttct gccatattga
    19681 tcaggaattt tattctttcg atgaaccgat ctagtgtgtc agataaaatc tctagcattg
    19741 ctaaaatcgt tgccaatgat aaactcatcc aaaaaaagct gcagactggt gacccgacac
    19801 atgcgattca aggaataaca aatgaaatca tgattgcatc gaatttagat tttatcgttg
    19861 tcatggaccc tgaaggcatt cgatattctc acgcagaccc aagttacatc ggtcttcctt
    19921 tctcaagtca tgaagatgtg aaaaaagtga ttggaggaca agaatttttc tctgaaaaag
    19981 aaggaatgtt agggttcggc ttccgctatt tcgtccctat ttattatgat caagagatta
    20041 ttggtgcagt ttgtgttggc ttaacaaaca acacgattga caatcaagtc aaagatggac
    20101 aaaaaatgat tgttttttca ttgattattg gacttagcgt aggcatcata ggcgccgttt
    20161 ttcttgccca aaaaatgaaa aaagtactgc ttggacttga accacaagaa atagcagaac
    20221 agttaagtga aaaaacgatt atcgaaaatg aagtagatga aggaatctta gccatctctt
    20281 ctgataaaac tatcctcttg atcaatacac ctgcaaaaaa cattttctac caaacagagc
    20341 agctattgga tttcgaagta ggaaaaaaat cagtgataat ctatatgacg ttttgtttaa
    20401 agagacgatt gagcatcaaa cgaccgttcg gactcaatcc atgtatttaa atgggataga
    20461 aactatttct agcgttacac ctctttttag caatgaccgt tttttaggag cagtcgcaac
    20521 tttacgaaat cgatcagaag taatgaaatt aatggaggag cttgggggga cgaaacaata
    20581 tataaactcc atgagagctc aaacccatga attcatgaat aaacttcatg tcatttctgg
    20641 tttgattgat ttgaagaagt atgaagaagt cacccatttt atccagcagc taaatcaaaa
    20701 ttataaaaaa gagattggcc aagtctcaag tctgatcaaa gtacctgcaa ttgccggttt
    20761 tttattaggc aaaataaacg aagccaaaga acaatctgtt gaaatgctgt tagaaagcga
    20821 ttcttttatc cctaaaatgg agatggatga ctccatccat tcacttttgc aagtgttagg
    20881 gaacttactt gataatgcaa aagaagccgt gctacaaaaa catgaaagaa acggacaggt
    20941 ccggattcat ttaaactatg acacagaagc tgaagtattc atcgtgaccg tctgcgatga
    21001 cggtgtcggg atatcagaag aaatctcaga aaaaatattt acgctaggtt tttcgacgaa
    21061 gggaatcaat cgtgggtttg gattgaatct catccattca atcgtcaaac gccacggtgg
    21121 atttttagaa ttttccaaac aaacaaatgg cggtacaatc gtctatctag aattaccaaa
    21181 aaaggaagat caaaatgatg acaaatgtcc tgataatcga agatgatcca atggttgcag
    21241 aattgaatcg tacttttgtg gaaagcatcc ctaatatgaa cgtaatcgaa agtttcagaa
    21301 atgtagaaga aggaaaaaaa tatttcagac aaaaaaacgc agatctgctg ctgcttgatg
    21361 tatacatgcc tggcgaaagt ggtatccatt ttttatcttg gcttagacag caaggaaatg
    21421 atatcccagt gattttgatc actgctgcag atgatatcga aaccataaag aatgtgatcc
    21481 gctacggtgc cttagattat ttgatcaaac cgttcacttt gcaacgtttt cagctggcga
    21541 tcgaaaagta tcttgctttc tctcagacaa tccaaacgac tgaaaaagcc gatcagaaat
    21601 tgatcgatca agtattcaac cacaccactc ccattcacga aataccatca ttcatcgatt
    21661 tgcctaaagg tctgtcaaaa ctgactttaa aaaaaataag tgcatttatt ctaaaagaag
    21721 atactatttt ttcaacaaaa gaactggctc aaaaaagctc actgtcacgt atatccgtca
    21781 agaaatattt gaatttttta gtagaacaag atatattgaa cgaaagaatc aaatatttgg
    21841 aaatcggccg gccgctaacc tgttatgaat tgacaaagaa tgggcggaaa aagctcacag
    21901 attactgttg agtcatcgaa ttatcccata caaaatagtc caagtataca gaagtaacaa
    21961 ctgtttactt ggactatttt taaacatttt attgacgaat atccatgttt tcttatctta
    22021 attgacgggc tttaggaaga gatacctcat ttttcgtttt tccagtttct attatttcac
    22081 gaaagttctc gaaacttgtc gaaatcatat ttgataatgc ctcatctgta tttgaaccta
    22141 catgcggggt tacaagaact ctagggtaca tttctactaa ttgctggata gcagggtctg
    22201 gaatcgtctc ccatggcttg aaggatcgga aaaaaacctc tgtttcattt gcaaaaacat
    22261 cggttgcaaa accagctaaa tgattgcttt tcaaagctct taaaatagct tcattatctt
    22321 gaagctctcc acgggctgta ttaatcaaga tgctaccttt tttcatttga gctaaaaatc
    22381 cttcattgat catttgatcg ttttcacctg ggatatgagg tacatgaata ctgacaatat
    22441 cgcttttggc taataactct tcaagcgagt ggaacgtcaa tactttttta gcagcttctg
    22501 tctgatgaat atcgtagccg atcactttgg ctcctagtcc cttaaacaaa acagcttccg
    22561 tcaaccctat cctgcctgtt cctatgatcc ctactgtgca atttctgatt tcacgactaa
    22621 acatttgctc atccactcga aaatctttga aagatgttcg gatcgtcgta tacgcagtat
    22681 ttctcaaaag catcatggca aaagtcaaag ataactctgc tatcgcattt ggcgaatacg
    22741 atggtacacg ggctactgtc ataccaaaat cagctgccgc ttgtagatcg atatgattga
    22801 ctcccacagt ccgtgtaaaa acataacgaa tcccatattc ctgcattttt gcaagattgg
    22861 tctcatctgc tatacaattt cccctcaaca atacagcatc atggtccttt gctgacacga
    22921 tattgtcatg tgtcaacagt tcttcataaa gactgagatc ataatggtaa atattcaatt
    22981 tttcaaaaaa atctatctcg ttcggacgaa caccgtaaca tgcgattctc atactttctt
    23041 cctccatttc ttatgaaaat aaacctatgc catgaatcat ttgtaataca acgatccata
    23101 caggtgtcag taccacagca aaaatagttg acagtaagga tgcattggag gctaaaagtg
    23161 cctccctatc aaaactgata gcataggctg ctgccactgt tgcagctggt gtagccatca
    23221 tgataacgat tgttgccagt gcttcaaaat tgactggtag aatattcgtt gccgtcaaaa
    23281 ctgctagaat cacgatattc aatgcaggta caaataccac tttgactaga ctgtaatacc
    23341 atgaagtttt ttcagatgca gcttttttga agcttacttc acctaatgtt gcgccgattg
    23401 ctagccacgc caatggtgaa cttaaaccag ctaaataatc catcggctga aatagccacg
    23461 gtgcagtctg gtcaattcgc aaaaacgcta cttggcttat ctctccttct gcacctgtaa
    23521 ctgacacttg tggcagatac ccttggaaca gccaaatgaa aaggccggca aaagtagcga
    23581 taatgattgg attgacgaac atcgctttga tatttttagc ttccatcttc aagccactca
    23641 tttttatgta tccataagaa tacaaaaaga ttcggtagcc aatattgaaa attgaggaat
    23701 acatcacgcc gacaggacca taaatcgcac tgacgatagg cgttccgaaa aaggtcgtag
    23761 aaccaaagat cgtcaggaca cgcaacgttg tttgcttatc ccctttatag cttaagaaaa
    23821 aaggttttga aactagaata agaataatat aaataactaa tccccaaatc aagacattga
    23881 ttccttgcat cagtaattct gtattgatat cttgcatgaa agctcgaaat gccagtgctg
    23941 gcaaagccac tgttaagacg actttcgata gaatttttcc aacagattca gaaaaaatcc
    24001 ccttttttct acaaacaaac cctaataata taataaaaac tgttgaagtg attgcactga
    24061 caatcgacat atctgtcaaa gtcgatcgaa aaatgtcaaa taagttcatc tttctcctcc
    24121 taattatgtt catttattca caataaaaaa agcttttatt ttgctaatac gtattaacat
    24181 ttttaatttt atctttacat tgttacttat tgaacaatag gaaattaaag aaacttttga
    24241 aacttatgta aagtgatttt tacggctcta taatttatgg gactgatgaa tcagaattga
    24301 ttcttcagcc ccatttttat tttaggtatt aaaaaacata tcgttctcta gtatgattaa
    24361 atcacgacaa aataaacaac tgagaggacg atatgctata tgaatgattc tatcaaaaaa
    24421 atgctgcgat taa
//
LOCUS       DAYYEF010000042        23825 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000042 DAYYEF010000000
VERSION     DAYYEF010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23825)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23825)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23825
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.043"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(53..787)
                     /locus_tag="ACHA1B_001911"
     CDS             complement(53..787)
                     /locus_tag="ACHA1B_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015267 - channel activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MIP/aquaporin family protein"
                     /protein_id="HFM8702670.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="ACHA1B_001912"
     CDS             1114..1524
                     /locus_tag="ACHA1B_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HFM8702671.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="ACHA1B_001913"
     CDS             1517..2218
                     /locus_tag="ACHA1B_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HFM8702672.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="ACHA1B_001914"
     CDS             2218..3804
                     /locus_tag="ACHA1B_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702673.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="ACHA1B_001915"
     CDS             3823..4044
                     /locus_tag="ACHA1B_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HFM8702674.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="ACHA1B_001916"
     CDS             4041..4802
                     /locus_tag="ACHA1B_001916"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HFM8702675.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="ACHA1B_001917"
     CDS             5182..5691
                     /locus_tag="ACHA1B_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HFM8702676.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="ACHA1B_001918"
     CDS             complement(5766..6305)
                     /locus_tag="ACHA1B_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HFM8702677.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ACHA1B_001919"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ACHA1B_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015935 - small ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0019843 - rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HFM8702678.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="ACHA1B_001920"
     CDS             7318..8169
                     /locus_tag="ACHA1B_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HFM8702679.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="ACHA1B_001921"
     CDS             8197..8832
                     /locus_tag="ACHA1B_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HFM8702680.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="ACHA1B_001922"
     CDS             8852..9625
                     /locus_tag="ACHA1B_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM8702681.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="ACHA1B_001923"
     CDS             10033..10830
                     /locus_tag="ACHA1B_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HFM8702682.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="ACHA1B_001924"
     CDS             10808..11221
                     /locus_tag="ACHA1B_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HFM8702683.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="ACHA1B_001925"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="ACHA1B_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HFM8702684.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="ACHA1B_001926"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="ACHA1B_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032300 - mismatch repair complex
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0030983 - mismatched DNA binding [Evidence
                     IEA];
                     GO_process: GO:0006298 - mismatch repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HFM8702685.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /locus_tag="ACHA1B_001927"
     CDS             15998..16558
                     /locus_tag="ACHA1B_001927"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0047429 - nucleoside triphosphate
                     diphosphatase activity [Evidence IEA];
                     GO_process: GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase"
                     /protein_id="HFM8702686.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ACHA1B_001928"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ACHA1B_001928"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015574 - trehalose transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015771 - trehalose transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HFM8702687.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="ACHA1B_001929"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="ACHA1B_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HFM8702688.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="ACHA1B_001930"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="ACHA1B_001930"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HFM8702689.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="ACHA1B_001931"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="ACHA1B_001931"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009379 - Holliday junction helicase
                     complex [Evidence IEA];
                     GO_function: GO:0003678 - DNA helicase activity [Evidence
                     IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HFM8702690.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="ACHA1B_001932"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="ACHA1B_001932"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0009378 - four-way junction helicase
                     activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HFM8702691.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="ACHA1B_001933"
     CDS             21905..22483
                     /locus_tag="ACHA1B_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8702692.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="ACHA1B_001934"
     CDS             22535..23017
                     /locus_tag="ACHA1B_001934"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA];
                     GO_process: GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="HFM8702693.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="ACHA1B_001935"
     CDS             23134..23508
                     /locus_tag="ACHA1B_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702694.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7782 a         4286 c         5114 g         6643 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtagactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaca
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcaccgggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaacaa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaag
//
LOCUS       DAYYEF010000043        23551 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000043 DAYYEF010000000
VERSION     DAYYEF010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.044"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(364..1482)
                     /locus_tag="ACHA1B_001936"
     CDS             complement(364..1482)
                     /locus_tag="ACHA1B_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702695.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1715..1837
                     /locus_tag="ACHA1B_001937"
     CDS             1715..1837
                     /locus_tag="ACHA1B_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702696.1"
                     /translation="MHLIMIFSLLSIISLFAFSASRLLDAETQPIPVKVRKNDR"
     gene            1953..3260
                     /locus_tag="ACHA1B_001938"
     CDS             1953..3260
                     /locus_tag="ACHA1B_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008800 - beta-lactamase activity
                     [Evidence IEA];
                     GO_process: GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HFM8702697.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3379..4578
                     /locus_tag="ACHA1B_001939"
     CDS             3379..4578
                     /locus_tag="ACHA1B_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HFM8702698.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4605..5873)
                     /locus_tag="ACHA1B_001940"
     CDS             complement(4605..5873)
                     /locus_tag="ACHA1B_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HFM8702699.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     regulatory      complement(5928..5994)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
     gene            complement(6036..6682)
                     /locus_tag="ACHA1B_001941"
                     /pseudo
     CDS             complement(6036..6682)
                     /locus_tag="ACHA1B_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7090..7593)
                     /locus_tag="ACHA1B_001942"
     CDS             complement(7090..7593)
                     /locus_tag="ACHA1B_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFM8702700.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7716..8480)
                     /locus_tag="ACHA1B_001943"
     CDS             complement(7716..8480)
                     /locus_tag="ACHA1B_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016740 - transferase activity [Evidence
                     IEA];
                     GO_process: GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrmH family RNA methyltransferase"
                     /protein_id="HFM8702701.1"
                     /translation="MKEIQSVKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSSTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8587..8862
                     /locus_tag="ACHA1B_001944"
     CDS             8587..8862
                     /locus_tag="ACHA1B_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HFM8702702.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9578..10531
                     /gene="yidC"
                     /locus_tag="ACHA1B_001945"
     CDS             9578..10531
                     /gene="yidC"
                     /locus_tag="ACHA1B_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003674 - molecular_function [Evidence
                     IEA];
                     GO_process: GO:0051205 - protein insertion into membrane
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HFM8702703.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGGAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAAKPADNKQATKQIKQPKNSTNNKGRNAGRQQKRK"
     gene            10653..11862
                     /locus_tag="ACHA1B_001946"
                     /pseudo
     CDS             10653..11862
                     /locus_tag="ACHA1B_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(11907..12307)
                     /locus_tag="ACHA1B_001947"
                     /pseudo
     CDS             complement(11907..12307)
                     /locus_tag="ACHA1B_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723846.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(12554..12988)
                     /gene="tnpA"
                     /locus_tag="ACHA1B_001948"
                     /pseudo
     CDS             complement(12554..12988)
                     /gene="tnpA"
                     /locus_tag="ACHA1B_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005576373.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13166..13532)
                     /locus_tag="ACHA1B_001949"
                     /pseudo
     CDS             complement(13166..13532)
                     /locus_tag="ACHA1B_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            complement(13546..13831)
                     /locus_tag="ACHA1B_001950"
                     /pseudo
     CDS             complement(13546..13831)
                     /locus_tag="ACHA1B_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            complement(13840..14031)
                     /locus_tag="ACHA1B_001951"
                     /pseudo
     CDS             complement(13840..14031)
                     /locus_tag="ACHA1B_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(14031..14507)
                     /locus_tag="ACHA1B_001952"
                     /pseudo
     CDS             complement(14031..14507)
                     /locus_tag="ACHA1B_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290865.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
     gene            complement(14975..15328)
                     /locus_tag="ACHA1B_001953"
     CDS             complement(14975..15328)
                     /locus_tag="ACHA1B_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702704.1"
                     /translation="MAMSEKAKKYLKEIKGAKTIPELKDVEIAIKRDGILAWAEFTKL
                     NEAVEEKKVALRKKKQETSLQEILFWAYKKESDKLLKMMDEGADKDAIQMQVQRYDSI
                     GQIIAEADLEDEYEV"
     gene            complement(15456..15866)
                     /locus_tag="ACHA1B_001954"
     CDS             complement(15456..15866)
                     /locus_tag="ACHA1B_001954"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702705.1"
                     /translation="MEEIMQMILGNAKFQLGQVVSTPAVLETFNPLQTANGIPEALSN
                     LWFRQEISIAEIEDAVLDAKNGKELANSLNRIKLFRKFTLDRELDGMVRLKGTDVWKN
                     ISYLKVYTATPPKKPTPPRFQSNGWSLFFSHKSA"
     gene            16025..16216
                     /locus_tag="ACHA1B_001955"
     CDS             16025..16216
                     /locus_tag="ACHA1B_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702706.1"
                     /translation="MIIRDDHIYTCDSCHYSFPADEQPERCPDCEKTATRLDTEIETE
                     DYYRVRAEIKAEIKALNAG"
     gene            complement(16258..17124)
                     /locus_tag="ACHA1B_001956"
     CDS             complement(16258..17124)
                     /locus_tag="ACHA1B_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HFM8702707.1"
                     /translation="MEELFSNALKSVKSNRVLYTASFFARSSLLYLQEIGQLTALKAH
                     TSRRTGLSSYLCFLVEVGSGTLEYKGQKYTLQVGDMVFIDCLKPYVHESSEDDLWTLR
                     WCHFNGIGMTEVYKKYLERGGQPVFKTSKTDKYADLLRSLHMVAEGQEYVRDMKINVL
                     LSELLMHLMEDSWNPDKVPNFSTKKMELQNIKQYLDDHYTEKITLDQLSAEFFINKQY
                     LAKIFRETYGTTVVGYLNQKRITQAKHLLRFTNLSMEEIATKIGITDANYFSRTFFKV
                     EGVRPSEFRKMW"
     gene            complement(17148..18800)
                     /locus_tag="ACHA1B_001957"
     CDS             complement(17148..18800)
                     /locus_tag="ACHA1B_001957"
                     /EC_number="5.4.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016868 - intramolecular
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HFM8702708.1"
                     /translation="MNYKVEYERWLNHANADIIEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLADYLNKNYEAASVVVGYDSRIKSDVFAKTAADIF
                     AANGIQVHLWPELLPVPTVSFATRYLKADAGVMITASHNPSKYNGYKVYGADGCQITT
                     EAATAILAEIEKLDIFADVKMDGDASKIASIQSEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEIKEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKSAHGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PADPVMVKTIVTMDLGERIASNYGVRTIDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLLDKLNEIYTKYGYCLNTLHSF
                     EFDGAAGFTKMQEIMVEFHKGLDIIGGKKVIETLDYSKGLNGLPKSDVLKFMLEDNCS
                     VVVRPSGTEPKLKTYISVSAENKEAAEAMEAIMAAELAEMFE"
     gene            complement(18805..19599)
                     /locus_tag="ACHA1B_001958"
     CDS             complement(18805..19599)
                     /locus_tag="ACHA1B_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004476 - mannose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I phosphomannose isomerase catalytic
                     subunit"
                     /protein_id="HFM8702709.1"
                     /translation="MTLTEVLQEHPEFLGTHPQTKGELPILIKFIDAKKDLSVQVHPT
                     DEYAIEKENGQLGKTEMWYVLDASLIYGLQKITEEAVIREAIAQGTVERYLQKVPVKK
                     NDVFFIEAGTIHAIGAGALIAEIQENSNLTYRLYDYDRVDKNGKKRELHVDKALEVAN
                     LKGLSEPKQPLRVLKYRAGVAAELLCRCKHFEVSRMIVNTERRQTVHYRADSISFRVL
                     LCVNGCGTVRFDNESLDIYKGDCLFVPADSTEISIHGSIQFLDVRG"
     gene            complement(19791..21104)
                     /locus_tag="ACHA1B_001959"
     CDS             complement(19791..21104)
                     /locus_tag="ACHA1B_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="HFM8702710.1"
                     /translation="MNIVLLSGGSGKRLWPLSNDIRSKQFIKIFKTEDGYESMVQRVY
                     RQIKKVDNDATVTIATSKTQVSAIHNQLGEDVGVSVEPCRRDTFPAIALATAYLVDVM
                     GIDPEESVVVCPVDPYVEDDYFEALKSLSDQADKGEANLVLMGIEPTYPSEKYGYIIP
                     ESAEQTAFVNTFKEKPSEAVAKEYIAQGALWNGGVFVYKLKYVMERAHQLIDFVDYQD
                     LFNKYDTLTKISFDYAVVEHEDKIQVQRFAGMWKDLGTWNTLTEGMEESIIGKGVMNE
                     NCDGVHILNELDVPVLAMGLHDVVICASREGILVSDKEQSSYIKPFVDKFEQQIMFAE
                     KSWGSYKVMDVEAESMTIKVTLNASHSMNYHSHKNRDEVWVVLAGTGKTIVDGYEQVV
                     KAGDVITMSAGCRHTIMADTELKLIEVQLGKDINVKDKQKFELEY"
     gene            complement(21172..22116)
                     /locus_tag="ACHA1B_001960"
     CDS             complement(21172..22116)
                     /locus_tag="ACHA1B_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014424865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase family protein"
                     /protein_id="HFM8702711.1"
                     /translation="MMEKDAKIYVAGHRGMAGSAIVRELNRQDYNNIITRTHKELDLC
                     RQDAVEAFFAQEKPDYVFLAAAKVGGIIANQNALADFMYENMILEMNVINSAWENGCK
                     KLQFLGSSCIYPRMAPQPMPESCLLTSELEKTNEAYALAKISGLKYCEFLNKQYGTDY
                     ISVMPTNLYGPNDNYHPTHSHVLPALIRRFHEAKEAGLPTVTCWGDGSPLREFLYVDD
                     LANLCVFLMNNYSGDETVNAGTGKELSIKELTEMVAKVIGYEGEILWDTSKPNGTPRK
                     LLDVSKATKLGWTYKTELEDGIRLSYEDFLNNPMRAER"
     gene            complement(22153..23238)
                     /locus_tag="ACHA1B_001961"
     CDS             complement(22153..23238)
                     /locus_tag="ACHA1B_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFM8702712.1"
                     /translation="MNKHICFYLSSHGFGHIARNLPIIMATLCRCEAKITLVCGANHL
                     DFAKRNLEQELPKELIDRVRYRPINTDIGLINREGTLLVDTGKLTEICEYFLAKVPSL
                     AKTEAEWLKREAVSAVLCDMPIWAMDACDMAGVPFLYVGNFTWTELYREFLPEHIWKE
                     YAKRYGKIQHTMLYALNNEEMLEFLQNSEKTPTSVVARPIHNDEVQRIKSQHEKPPVF
                     VALGMSARFKQPIDVSHAPYDFITTLGVPLVGENVTVISNSTPNTQDYIAAADYVITK
                     AGWGTVAECILAQRPMALFARDTVLEDRTTICKLQKLGLAISVTPENLHRVERVIEDL
                     KQLDTSNFDTFYDAASEIADKLISLMQ"
     gene            complement(23246..>23551)
                     /locus_tag="ACHA1B_001962"
     CDS             complement(23246..>23551)
                     /locus_tag="ACHA1B_001962"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HFM8702713.1"
                     /translation="QHTVRDFTEKAFAANGMTIRWEGTGIDEKGYDVETGKMLVCVNP
                     QWFRPTDVDNLWGDPTKAKTVLGWNPQKTSYEELVNIMAKHDRELAKREAAMKNAVK"
BASE COUNT         6697 a         5327 c         4451 g         7076 t
ORIGIN      
        1 taaacggtgt tccagaagta gcttcttcgg aaataagccg aaatttcaca aaaatttgag
       61 aaataatttt tgtcaatctc ttcttatttc ttgaagctga ccacttctgt cacaacctct
      121 tccttaaacg gtgttcaaaa gcttgcatct gcggtaataa gcccaccaaa caaaaaatat
      181 gaagagctat ttttgcttgc tgttcttatt acttgatgca gaacagcttt ttcacaacct
      241 ctcatacacg gtgtttaatc agctgacctt cggtattagc tcaaaaaacg gaaaaatatg
      301 tgaaactatt tttccgtttg tttctctaat actcaggtca aaacactgat ttcacaacct
      361 cttttaataa cgaagaatcg ctgtcagact cttttcatct ggcgcatctt tttgatccaa
      421 aataaacact ttcccgccat taatgatcac atcatctgct aatgcattca acacttgacg
      481 ccgatcatat tctgtttcag gatcttcacc gaaaccatca gctaagtttg acgtagcgat
      541 aaataaatgt gacacttttc cttctttcgc agctggaacg atatcaacta actgatcgat
      601 gaatttctta tctaagagtt tattgtattc ttttgattct tgagctgcga gttcacttga
      661 cagcttcttc gccccttctt cgatatctct aaaggatagc tgcgcaggag aagcagaaat
      721 cgcaacgtct gcacaataat agggattttt agcaattttt ttgaacatcg tctgattttc
      781 tggtaatgca aataaataaa tcggccattg ttcaggattt tcgaaagaat ccttcaagta
      841 cgtatcaaca gcttggtaat agttgaccca atcgatctct acttcttcat cttttggatt
      901 tacgccatgg aaagttactc catctcgggc tccgcctcct ccattagaag agaagttcaa
      961 accgccacct gtcagttcag atcccaatgc agtaacgaca tcaaccggtg ccccttctgg
     1021 tagagatact tcttttactt gtttgttgct gacctcatac aatttcatgg agtcgcggtt
     1081 caatcccaat aaataataag aatagttgaa ctgcccattt ttgataatag ccagtaaata
     1141 aggaagatca cttacatagt attgatcgtc taccgggata ctcaaacgat ggatataggt
     1201 ctggtcagca gttataatga ccgctacact cgtagttgca ctacgccaaa acgaaggatc
     1261 tcctaacaaa ttttcaattt tttcttggaa cggggaccag tcatgttcgg aatatttttt
     1321 ctcaaaacgt ttctttgctt ctttcgcaaa atttttgaat ttgatctgat ctttttccac
     1381 atcttgatgg gcgacatgcg tattcagcat gatcgtgacg aatggtcctt tagcgccttc
     1441 tgaagtcaat tgtgtcaata attctttatc cttttttgcc ataaacgtac ccctcctaaa
     1501 aaaatcattc ctttgtttct atctaaagtc taccacaaca ctatttttcc atacaataaa
     1561 acgtatctaa aaaaataaaa cggtttctac ggttttaaat ttagctattt ttttaagtta
     1621 tcttcataat ttcctcaatt atttagcccc agtcttcaac tattcttcat gaaatgctga
     1681 taaactaaga aaaagaataa aagaggtgga tcttatgcat ttgattatga ttttcagttt
     1741 attaagtatt atcagtttat ttgctttcag cgcttcccgc ttattagatg cggaaacaca
     1801 gcctattcct gtaaaagtac gtaaaaacga ccgctaaact tccataacgc gcgttcttat
     1861 cctaaagttt tttcagaaac attgaaactc tctcccctct ctgataaaat tttaatttgt
     1921 agcgaaacaa attaattaca aggagatcgg atatgtccat aaaaaaaaca cgtctagtcc
     1981 tattattggc tagtctcatt ctttgccttg cttcttttct accagctgtt gctgtgcaag
     2041 ctgaagatac gttcaaagta aatgcaaaag cagcttttgc tgtagatgcg caaagcggta
     2101 agattcttta tgatcaagat ggagaaaaaa ccatggggat cgcttcaatc acaaaaatca
     2161 tcggtcttta catcgtcctt gatcaagtaa aagaaggaaa actgtcatgg ggtgataaag
     2221 tttcgatttc agattatgca gaaaatttga gtatcacccc agatttatcg aatgttcctt
     2281 tgcataaaga aaacacctac actgtcaaag aattattcga ctctgcaatc atccagtcag
     2341 ccaatgcttc aatggtggcc ttggcagaaa aaatctctgg cagcgaagct aaattcactg
     2401 aacgaatgaa agaacaattg aaagattggg gaatcaaaga tgcaacaatc gttaatgcat
     2461 caggattgaa caactcttat cttggcgaaa accgaccaga aggcactgga gaaaacgacg
     2521 aaaatcaaat gtctgctcaa gatgtggcca tcgttgcccg ccatttgatc ttggatttcc
     2581 cagaaatact ggatgtatca agtactacga cccaaatgtt tggcgaaaat acgcaatcac
     2641 cagtggaaat ggtcaactgg aactggatgc tcccaggatt cgttaattac aaggaaggcg
     2701 tggacggatt aaaaactggt acgactgagc ttgcaggtgc ttgtttcgtt ggtacgatca
     2761 ctaaaaacga tcaacggatc atcactgtcg tattgaatgc ggacggccat gcggaaaacc
     2821 cgagtgcccg cttcaatgaa acagaccgtt tgatggacta ctgctatgac aattggtcag
     2881 aaaaagagct cggaaaagct aacgcaagta ttcctagtct aaaaaccatt gatgtaaaag
     2941 acggaaaaga atcaacagtt cctgttgtgc ttaaaagccc tgtaaaagta tgggtacgaa
     3001 acgatatgga tactggcaaa ttaacgatca cgccaacact tgacaagaag caagtcactg
     3061 acaatgagat ccaagcacct atggataaag gtacaaaaat cggtaccgct acgatcacct
     3121 tggcagacga taaattaggc tatttagaag acaacaatgc accatcaaca gagatcatta
     3181 cggataaaac agtggaaaaa gcgaatatat tcgtgattgg ctggcgacgc gtcgcagaat
     3241 ttttcggcaa cttgttttaa ttgaacaata agaaaaacat ctttccatcg gaaagatgtt
     3301 tttttgcttt ttctagttta aataacagct tttttcatct attttcgtta tactgtataa
     3361 gaaaaaggag ttgaatttat gaatctaacc agagatctga tctttttagt tctctatctt
     3421 attggggtat tctctatcgt ttattggcga aaacagaaga aggatccttc cttgttcttt
     3481 tacggcagta cgtggacatt tacggtaatc ttaacttatt ttgtcgtgtt ggaaattttt
     3541 tattcgacct tttatttttt gattccattg ttgttcttta gtatctttgc tttttcttat
     3601 ttcacagaaa aacgaaggct actgaatggt cttttattca atgttttact catcagtttc
     3661 ggcatctact tgtttgtctt gctgtatgaa acgcaaaata tttttcttgg cggactgatc
     3721 gccttgatca cgattccatt gctacttgtc cttttatttg gtatttatgg attgattgtt
     3781 tttctttttt ggaacggggt cacagtttta cgtagagaat cgcattcatt agctaatctt
     3841 ttaacgttga tactagccat ttttcttaca ctgtttcttg tttttgactt tttcttgtta
     3901 aaatatttgc cgcaatggat aaatgctttg tttttctgcg ttcccctgat cttgatctat
     3961 ctatttatcg tattctacaa ctttttgact gtctcattct tgtatcagtt caaccggcct
     4021 cgatacaatc aagacttcat cgttgtgtta ggcgctggat tgatcaatgg agaaacagtt
     4081 tctcctcttc tagccaagcg aatcaataag gcaattgctt tttatcgggc tcaaagccgt
     4141 gctacattaa atccgcccat cttattgatg tctggcgggc aaggagcaga cgaaaaagta
     4201 ccagaggcca ttgcgatgaa acaatatgcc atggaacaag gaatccctga aagagacatt
     4261 cttgtcgaaa ccaattcgac aaccactttg gaaaacatgc tctattcaaa ggaaatcatg
     4321 gatcagcaaa tgaaagggcc ataccgcgcg atctttagtt ccaacaatta ccacattttt
     4381 agagccggtc tttatgcgcg gcaagccaaa ttgaaagcaa atggtattgg tgcaaaaaca
     4441 gctttctact acttgcctaa tgcgttttta agagaatacc tcgccatctt gatgatgaac
     4501 aaaaaaagac atatgatcat ttgcggattg cttttcgcag gctccgcatt cttatcgctg
     4561 attactttac ttttctaaaa aaacaaggtg tgacaaaaca tatgtcacac cttgtttttt
     4621 tctttcattc tcttaactat tggcaaaaag agtatccctt ttttgaccgc tacttgctga
     4681 gcagaataaa taccgctgtt gcctgaacac ataaagctga tcaagcagat cataaagaag
     4741 tatactgccg cttgtgaacc gaacaattcg atccccatca caaagcaggc aatcggtgta
     4801 tttgtcgcac cagaaaatac tccgataaag cccaatcctg caagaaaagg aacagaaaca
     4861 tggagcaaag gcgctagtgc tgcaccaagc gttgcaccaa tttcaaacaa tggtgtcact
     4921 tctccccctt gatatcccgc gcctaaagac aaaactgtga agaataactt cccaataaaa
     4981 tcatagacat gtgcctgtcc attaaatgat tcttgaagta acggaagact caatccgaga
     5041 taacgttgtg tttgcaaaat caatgctgct gccacaacta cagctccacc tatcgtattt
     5101 cgacaaacag gatgaggaat ccattgtgca tatcgcgctt ttaaaaagac gatcgaacgg
     5161 ctgaataccc aaccaatcaa accaaaagca atcccagcaa caaaaacttt gaagaacagc
     5221 aacatactcc attcaggaat cacacccatt tggtaatgta gatgagaaac accatagctt
     5281 tctgtcatga aatttgcaaa cagtgcagca aagaagctag ggaagatcgc ttctgttcgg
     5341 actttcccga ttgccaacac ttctaatcca aataatgttc cagctaaagg tgtgccaaat
     5401 acagaactaa aacccgcact gattccactg ataatcaaga tttcccgttc tgatttatcc
     5461 aatcggaaca aacgtgccgt attatctgct aacgctcccc ccatttggac tgctgttcct
     5521 tcacggccaa cagatccccc aaataaatgg gtagttatgg ttccaaacag tgtaagtgga
     5581 ataagccgca acgggatttt ttcttctcca ccatttcctt gatcgatcac taagttgttt
     5641 ccacgactag aaagtccgcc gtgatacgca tagagataag caaaaagcgc accactaact
     5701 ggtagtagac aaaggagcca aggatgtgat agtcggatat ctgtcacaac tgtcaggcta
     5761 tttaagaaaa aagcagacaa gctccccatg aatataccga gaatcgctgt gatcaccagc
     5821 cacttcagca tatacactaa aatgcgtact ggactcggta attgtttttc cataaaaaat
     5881 tcctcctcaa taaaaaaacg cctactaaag aaaggggctg tccccagact ttagtaggcg
     5941 tcattagcta tctttcgtta gcatttaaag gcgaacacca tcacctattc acttccatta
     6001 aaagatagca tatttttctg taaaaaacaa taaaattatc gttctttctt tacacgttca
     6061 gcaaattcat agaaaggagc caatttcgtt aactgttgat tacattggtc actatcatga
     6121 caaatataat tccccttttt cgtatacgtg ccatcagaac ctgctttcgt tgtagaaaga
     6181 aaaagcgaaa cattcgatgt tttctgacag attgcacaga ttcccttatt tatcgttggt
     6241 gataaagtac cgctaatccc ttttaatttt tcatcttcgt aatagaccat gaattttttc
     6301 tgcgtacctg gatcattcca gccgatgtac gtatgttctt gcaagtcgat ttcattccaa
     6361 gctggttgtt tgagtttttt cacttttcgg aataatttct cgatttgtgg tttgctaggc
     6421 tgcataaacg gctgaacgat ttgcttcagc tcctccaatg ctctttctgc ttgcgctttt
     6481 gtcagtttta cgtctaaaac tgtcgttaaa aatgtatcga ttctggcagt tcgtgatcta
     6541 atatgtctcg aatcttttca gctgctagtg cctgaactgt ttgtaccgtt tttggatcat
     6601 tgacagatga gtacgcattt aataactgtt ctacttctct tattataaaa aaatattggt
     6661 atggttttat tgtttgttcc atgattttaa agtcctttct tctaaccaaa gtgcatactt
     6721 tgtagaaaaa agtgatcttc tgcaaagtat gtgttacctg aagatcctgg actcttttaa
     6781 ataagatacg ttttgcatct tatcatcacc ccctttaatg cttattattc tatgtacatg
     6841 attcattcga taaataaaag taaaccgtat cttgaacaga tagtcaactg caaacagaaa
     6901 aaaggactgt gacaaaagtc gtgtcaaagt cccttgtttc gaatgaatgg tgttcaaaag
     6961 cttgcatctg cggtaataag ccgaaacttc acaaaaattt gagaagtaat tttcgtaaat
     7021 tccttcttat ttcttgaagc tgaccacttc tgtcacaacc tcaatatggt ctattattgg
     7081 ttttacctgt taaatcgagg attctttccc aaagtaacgt tgccatctct tacgcatact
     7141 tgcagacatg ggctgagccg cttctttgac tgcgcagtat ttgtccacga atgtcacaat
     7201 atatccttct ttatacttag gcggtgcgat cgttgcaccc cacatgtgct tcaaaatgat
     7261 atctcgctca agatccgaca aatcggtgat tttttctgca ttctttacag caattcttgg
     7321 atggatatac gcatgtgtcc cctcgtcaaa tttcgtcgta cgccaatcat agtagaacag
     7381 atcatgcaaa agtccagcac gcgctgttgc tttagcattg ccaccccatt tttttgcgag
     7441 cagataacta tagtaagaaa cactgatgga atgctccaaa cgagtggaat gaacatgctg
     7501 tgtgtaattc gctaattttt tcactgcttc tgtttctaaa agatcttgta cataagacat
     7561 atattcttcg tcttcacgcc atttttctgt cataattatc gatttgccac ctttttgaat
     7621 ttcattttct tctgaaattg atctaagtat accaccagtg ttcggattat tctagtcgct
     7681 ctagataaaa tagctaaagc ttaatagttc cttaatcata aagaaaaatg ataaagaacg
     7741 atccctgctg cgactccgac attcaatgat tccgcatttc ctttcattgg gatatatacg
     7801 ttctgatcag tcgaagacaa gatttcctga cttactccct gaccttcgtt tcccatgatt
     7861 atagcgaaat cctctgtttt ttctactttg tctaatgcat gtgcttcttc atttaattct
     7921 gtaccgtaca ccgtaaaccc tttgcctttc attacaggga tcacttctgc caaatctttt
     7981 tgtaacacag gcaaatgata attgcttccc tgcatgcttc gcagcacctt tgtactataa
     8041 atatctgccg ttcctttacc taataaaaca ccagccatac caaacgcatc tgccgtacgg
     8101 atcatcgttc ccacatttcc aggatcctgt acattatcta gtaaaagcca gcctcctgaa
     8161 aaatctggcg tatcttcaga tgttaacgtc atcactgcta agatcccttg cggtgtaggt
     8221 agatctgaca tagcggtcat gacctcatct gaaactagaa aagtagaaat ctctttgttt
     8281 acagccagcc agtctcccca ttctttcata cctctctgtg tcacaaaaag ttcttttatt
     8341 tctgcatcag acgacgcagc ttcttcgatc agatggaacc cttccaaaag atattctgcc
     8401 ttttcttctc tgtatttctt tttatgtagt ttttttaatt ctttgattct tggatttttt
     8461 actgattgga tctctttcac attcctcacc tcaactgatt atatcatgga ataggtgctt
     8521 gagcttgttt catcctaaaa aaatcggtat cattgattta taaaacagga aagaaaggtg
     8581 acgaacatgc gcaaagttaa aatgaatgtc caaggacgtg tccagggcgt gggatttcgc
     8641 tatatgacca agatggttgc tgatcagtta ggcgtgaccg gaacggtaaa aaacgaagac
     8701 gacggctcag tcacaatcga agcaatcgga aatgacgaca tcatccaaaa atttatcgaa
     8761 gaagtcaaga agtctccgag cccaagtgga cgagtgcagt atgtggatgt ccaagaagat
     8821 ccgatgattg aggaacgaaa gaaatttgat gtggtgggat aaggttgttt ttgaagcgct
     8881 ttgcctcgag tattaaggag aaacattttc caaatagctt ctcatatttt gaaatgtaat
     8941 gacttaatac cgagaggcag ctgataaaac accgtcaata aggttgtgaa aaagctggtc
     9001 tgcatcaagc attaaggact ggttgtgaaa aatagctctc catatttttc aacaggctgg
     9061 acttaatgcc gtagatgcaa gcttttgaac atcgtcgata aggttgcgaa aaagctgatc
     9121 tgcatcaagc attaaggact ggttgtgaaa aagtcgctta gttttgagta ttaaggaaaa
     9181 ttttgtgaaa atggctttcc acatttttgc ataaatttga cttaatacca agaaactgac
     9241 ttttgaacat cgtcgataag gttgtttttg aggcactttg cctcaagtat taaagacagg
     9301 tagtaaaaaa gctgatctat aacttgcaat aaatttgctt aacccatatt ttccagacag
     9361 aacaaaaaag tttttagttt tttaaataag aaagaaacac ttggaatcac tcttttcttt
     9421 ctaagtattt ctttcttgat tttttgtctt ttttcaaaat ttttcgctac gaaaaagaac
     9481 gaatatttat atgaaatttc tatgaagttg attgaattcc atgcgctttt ttagtatagt
     9541 taagtttgtg taaaaattat agaagaggaa gtattctatg aataaatgga aaaactggtt
     9601 attgggatcc ggacttgtca gtatcctgct ctttttatct ggctgtgtgc ggatggattc
     9661 aaacggaaac cctgacactt caggaatcgt ttatcgagta ctcgtccatc ctatgggcca
     9721 agcgattaca tatctagttg agaatttcaa ttggtcttac ggctgggcag ttattgcaat
     9781 gactgtgatc gttcgtatca tcatcttgcc actaggtatc agtcaatcga aaaaaacaat
     9841 gatccaatct gaaaaaatgc aagcgttaaa accacaagtt gaagcagcac aacaaaagct
     9901 aaaagctgca acaacacgtg aagaacaaat ggcagcacaa gcagaaatgc agcaagtata
     9961 tcgcgaaaat ggattgagta tgaccggcgg aatcggctgt ctgcctctat tgatccaaat
    10021 gccgatcttc tctgccttgt attttacggc tcgctacaca gaaggtatcc gtgaatcatc
    10081 tttttacggc atcgatctag gctcaccaag tatggtgctt gtggccatcg cagggggcgc
    10141 ttatctgctt caaggatata tttcaacaat cggtattcct gaagaacaga aaaagacgat
    10201 gcgtacgatg ctgatcgtct ctcctgctat gatcgtcttc atgtcgatca gtgcgccagc
    10261 cggtgttaca ctttactggg tagtcggtgg tgtgttcagc tgtctgcaaa cattcatcac
    10321 aaacgttata atgaaaccgc gtttgaaagc acaagtggca gaagagttga aacaaaaccc
    10381 gccaaaacaa gtcgttactc caagaaaaga cgtgacagaa tcagcagcaa agccagctga
    10441 caacaaacaa gcaacaaaac aaatcaaaca accaaaaaac agtacaaaca acaaaggccg
    10501 caacgcagga aggcagcaga agcggaaata aaaatatatg acaaaaaact gtagacaaat
    10561 aaaaaaattt ctttgttcta cagttttttt gttacaatta aagaaaacgt tcgcatttcg
    10621 aggaggaatg tataatgatg tccaaataat caatgtatag tcgaatggaa gaagacaaaa
    10681 tttcgctaga tgcacttgtt cctaaaaatc atttagtccg taaaattgac aaattattgt
    10741 catttgattt tatttatctc attgttgaat caacttactc gaccattggt cgccctagcg
    10801 ttgatcctgt cgtcttagta aaattagtat tcattcaata tttatttgga atttgttcga
    10861 tgcgtcagac cattaaataa gttgaaacaa acctagctta tcgttggttt cttgggctta
    10921 gtttaattga taaagttcct catttttcaa cttttggtaa aaactatgca cggcgtttca
    10981 gagaaaccga tttgtttgaa cagatattta tcattattct cgaataagca gttgatgcta
    11041 gatttattca tgaagaaatt ttgtatatgg attcaactca tattaaagcg aatgcgaaca
    11101 aacgtatttt tacaagagat atggcacata aagaagccat tttataccaa aaacaattag
    11161 aagaagaaat caatgaggca agaattgccg aaggcaaacg tccttttggt tcaatcattc
    11221 gtcaggaggt ggtcgaaaga aaatttagca tcgcagatcc agaaagtggt tattatgtaa
    11281 aaacagaacg agaaaaacag tttgcttatt ctgctcatac cgttggtgat gaaaatggtt
    11341 ttgtattaga tgtcatgatt acgcctggaa atctacatga tagccgaatg ctcgtgccac
    11401 aaatcgaacg cgttaaatca cgttatggtg tagctgctaa tgctgcgtac aaaacacctt
    11461 ggaacgtcaa gtatttaatc gaacgaaaac tacgacccat tctcccttat atcagtttcg
    11521 cacaactact cgagatggct ataaaaaata tgtatctaaa tcttttattt gtgaaagttg
    11581 tccattattg aaaaattgta cagaaagcca aaaacaccaa aaagaaatac atcgacatat
    11641 ttgggaagac tacttagatg aagcagaaca tttacgccat acggtgtaca atcgtgaaaa
    11701 atataaaaaa agaaaagaaa cgattgaacg catttttgca gacgcaaagg aaaaacatgg
    11761 aatgcgctac accaagtatc gaggcttgga aaaaatcagg tgcatacaat gcttgttttt
    11821 gtcgcaatga atctgaaaaa attagctact tggcagtggg agcatatgtc gttatatctt
    11881 ttattataca aaaatagaca aaagtatcag tctacactct tagtaaagag gaaactgatg
    11941 cttttgtcta cagtcttaga gagtgggaca atagtttttt cttctttacg tcttttcctc
    12001 tccatgtatt ttcctaattt tcttaattta acgccatgag tgccaagcca atgtcaatct
    12061 tggctccttg tttccttcat aagtggaaat ccgtttccga tagatcgaac cttctttttc
    12121 ctctaaaagt ttttttacat tctgctttga aataacgcca tgtattattc actaaaattt
    12181 gtcggtttcg ctcacttttt gctttcgtac attgactacg aacaggtcag caccgaccac
    12241 tttcacattc gtaaattttg aagacacgta taaatccact tttatctttt cttcgactaa
    12301 agcgttgacc gcaaaagcga catctgtttc agaaatatat tgttccatat ctaatggtaa
    12361 aattttttgg ttgatggtat aatttttaaa cataaagcac tcgcttcctt tctgattggg
    12421 tttggtcact ttaatcctac agggatgagt gctttttgtg taccttaaaa tcagtaaata
    12481 tccatccgtg aaaacgggtg gctttttaac agccctagaa gggctcacca ctcacagccc
    12541 tatctctctt taactattta aatggatcta catactcttg tttacttata ctgtctctaa
    12601 ttcgatcatc tgcttcttgt tctcaaatat atatttcaat tgttttttga tttaacccaa
    12661 ccgtactcac gtagtatcct ttggtccaaa agcttttatt cccatactta tatttcaaat
    12721 ttgcatgttt ttcatggatt aaggttgcac ttcgtccttt taagtagccc ataaaactag
    12781 aaatactaat ctttggcggt attcttacta acatatgaat gtgatcaggc attgcatgag
    12841 cttcaatgat ttcaacatct ttcctctcac acaattttct taatatctgg ccaatactta
    12901 ctcttaactt tccataaatc acttttcgtc gatacttcgg ggtaaagact atgtgatact
    12961 tacaatccca tctcgtatgt gctaaacttt tatcgctaaa gctatttcgt ccacgcgtag
    13021 aaacgcgcgt ttttttgttt cgtacgctac gccaacgaaa ctgactaaag tcaataaaaa
    13081 aagtggggca ataatcagat ttttttctga ctattgtccc actctctttt tattactctt
    13141 catcttctac tattccacta attaattagt tgacagatac aatgctttca catcctgcac
    13201 gaacaaactc gggctctgaa ccaatcactt gcgagttgat aaattcaatg accataggaa
    13261 gattaatccg acataaagtt taatctgttg tccttccatt atcagtttag aaatgatatt
    13321 agtaggtgta ccgcctaaaa gatcgcatag taccacaaaa tcatttaacg aatctatgac
    13381 agtaagagct tttgtctgta tgtttcagtg ccatcttctg gtaataaagg taacgtgtag
    13441 atattctctt gaggtcccat aatcattttt gtactttttt tcaattcctc acaaaatttt
    13501 ccgtgactaa tcaatatcaa ttttctactc atttttggct ctcccttatt tcgaaatcac
    13561 acacaatgca gataaagcca cacacaagta atacgataaa aatcgctcga gttgggtcat
    13621 atttttcttt cctaacaacc aataaacacc tcgacgatcc cagcgagtaa gattttagat
    13681 aatatcatat cgatatagtt ttgcatattc aatgtcacat cgccaatcgt tggtaccata
    13741 aaaatttaat atcaatcatt gttgcaacta atgctcctac catgaacact cttaataaag
    13801 tcgctacgtc cgttaataca gttaagcgag attacactag atgatctgtt cctgccaagg
    13861 caagagccag aagcggttgc ctgcccattt gcctttggtg tgtcggagct gtccgataaa
    13921 gttcaccgcc cgatccgctc tggctttgtc gtagtgacat tccgaaagca tgaatcggct
    13981 tggtgtgtat tcctttaatt tgggatagcc ctttggtctg gtttctgcca tcagctacca
    14041 cctcccaaca gagcctccat cgcatcttct gctccgacac caccgccatc accggcaatg
    14101 atacggcttc tggacgaagg cgtcagaccg aactgctcgg aaaatcggtt cataattttc
    14161 agataggtct gggcaataaa cacctgtggt acctgctgcc aatagccgga tagggttttc
    14221 acgatgatac cgtgctgggt aatgaattcc tcggcttcct tccagcgggc gtaggcttgg
    14281 cactaaccgg caaaggcagc catatccaca tctgtcaaga ttccgatggc ctccatctgc
    14341 tttgccagac gcttccattc cttctttgcc tctggttcca gccacttcgg acaggtcggt
    14401 gccttctttt ccggcgttga ctcttttgca ttgagtgggc gattgcccgg atttccctcc
    14461 agcttcttca tggctgtcgg ggttgatttt cttcctctgg ttgccacagt cgtcacctcc
    14521 cttcaatgta tttctgccag tagacagaga acagagccaa gtcgaaacct gactctcttc
    14581 tctatctgct aacttgtatt tcagtccact cttctgatga atcgcacccg caggattttc
    14641 aagatgccgc aggcaaattc caagaagttt ctgaccgcat cataaccatc gtagccgtgt
    14701 agccacatcc ttccacctcg ccgccgtcct cgtcgctgat ataaatgatt ctgtattcgc
    14761 tcatctgttg ttttctccag tcttttgttt ttttgtagta catatatcac tctaaaagtg
    14821 attattatca agtcgtttga aagccataat gtacacaatc attcgactgg tttttggttc
    14881 ataattgacc gccaaagtga gcaaaagaaa gggacctctg tctgtttcag aagtcccttt
    14941 cggtatttgg ttcttagtgg ttcaggctgt attctcaaac ctcatactca tcttcgaggt
    15001 ctgcctctgc aatgatctgg ccgatgctgt cgtaacgctg gacctgcatc tggatggcat
    15061 ccttgtctgc tccctcgtcc atcatcttca gcagcttgtc tgattccttt ttgtaggccc
    15121 agaaaaggat ctcctgaagg ctggtctcct gctttttctt gcgaagggcg accttcttct
    15181 cttccaccgc ctcgttcaac ttggtgaact ctgcccaagc aaggataccg tctcgcttga
    15241 ttgcgatctc cacatccttc agctccggga tggtctttgc acccttgatc tccttcaaat
    15301 atttctttgc cttttcgctc attgccatta gcgtttcctc cttgtttttg ggattttccc
    15361 ctttggttgt gtgtatattg ccatagtctc tcgactatat caagtcaatc cacaggcata
    15421 tactacacaa tcatttggag ctgtatttgt atacattatg ccgatttatg agagaagaaa
    15481 aggctccagc cgttcgactg gaaccttggg ggggtcggtt tcttaggcgg cgtggcggtg
    15541 tagaccttga ggtagctgat gttcttccag acgtccgtgc ccttcagtct gaccatgccg
    15601 tccagctctc ggtcgagggt gaacttgcgg aaaagcttga tgcggttgag gctgtttgct
    15661 agctccttgc cgttcttggc atccagaact gcgtcctcga tctccgcaat actaatttcc
    15721 tgtctaaacc aaaggttgct caaggcttcg ggaatgccgt ttgcggtctg cagggggttg
    15781 aaagtttcca atacagcagg ggtcgaaacc acctgtccga gctggaattt tgcgttccct
    15841 aaaatcatct gcataatttc ttccatgtga atcatccatt tctgccgttg tggtattccc
    15901 tttggcagta cagtactata tatcactctg aatcgtacat ttatcaagaa gcggattttt
    15961 gtggaatcac caattcgata taatagtaat tgcatgaaaa atctaagcac tggattggta
    16021 ggtgatgatt atacgtgacg atcacattta cacctgtgat tcctgccact acagcttccc
    16081 tgccgacgaa cagccagagc gttgtcctga ctgcgaaaag acagcaactc ggctggatac
    16141 cgaaatcgaa actgaagatt actatcgtgt tcgtgctgaa atcaaagctg agattaaagc
    16201 tttgaatgcg ggttaacgac aggtactgac cggcggctca acaccgccgg ctttttatta
    16261 ccacatcttg cggaattcgc tgggacgaac accttccacc ttgaaaaaag ttctggaaaa
    16321 atagtttgca tctgttatgc caatttttgt tgcaatctct tccatactta gatttgtaaa
    16381 gcgtagcaag tgcttggcct gtgtgattcg tttctgattc agataaccga caacagttgt
    16441 accgtaagtt tcacgaaaaa tcttagctaa gtactgttta ttgataaaaa actctgcact
    16501 caactgatcc agcgtaatct tctccgtgta atggtcatcc agatattgtt ttatgttctg
    16561 caattccatt ttttttgtag agaaattcgg cactttgtca ggattccaag aatcttccat
    16621 caaatgcatc agcagttcac tgagtagaac attgattttc atatcccgga catactcctg
    16681 tccctctgcc accatatgaa ggctcctcag caagtcagca tacttatctg tttttgatgt
    16741 tttaaagacc ggttgaccac ctcgttcaag gtattttttg tagacttccg tcataccaat
    16801 gccattaaaa tggcaccacc gcaaagtcca caaatcatct tctgatgact catggacata
    16861 cggcttcaaa cagtcaataa acaccatatc tcctacttga agcgtatatt tctgcccctt
    16921 atactccaat gtgcctgaac caacttctac caggaaacaa aggtaagatg acaatcctgt
    16981 acgcctagat gtatgtgcct tcagagcagt cagctgtcca atttcctgca aatacaaaag
    17041 agaggatctt gcaaagaacg atgccgtgta cagcacacga tttgacttca ccgatttcaa
    17101 agcgttagaa aacagttcct ccattacaag atttctcctt tcttttctta ctcgaacatt
    17161 tccgccagtt cagcagccat aatagcttcc atagcttcgg cggcttcctt gttctctgcg
    17221 ctgacgctga tataggtctt cagcttcggc tcagtaccag aaggacgaac cacaacagag
    17281 cagttatctt ccagcataaa cttcaaaaca tcagacttcg gcagaccatt caggccctta
    17341 ctgtagtcta aagtttcaat aaccttctta ccaccaatta tatcgagacc cttgtggaat
    17401 tcaaccataa tttcctgcat cttggtaaaa cctgccgcac cgtcaaactc gaaggaatgc
    17461 agggtgttca aacaatagcc atactttgta taaatctcgt tcagcttatc cagcaggctg
    17521 ataccctgag tcttgtagta agagaacatt tcacagatta gataagcagc gttaacaccg
    17581 tccttgtcac ggacatagct accggacaga tagccgtaag attcctcaaa gccgaagata
    17641 tagctgtcaa ccttaccagc cttttccaac ataccaatct gctcaccgat aaacttaaag
    17701 ccggtcagca catcgatggt acgaacacca tagttggatg cgatacgttc acccaaatcc
    17761 atggtgacga tggtcttgac catcacaggg tcagcaggca tttttccatg cttaattctc
    17821 tgagaacaga tgtagtccag aagtagcaga ccagtctcat taccagacaa cagaacatag
    17881 tcaccatgtg cgctcttaac tgcgatacca acacggtcgc agtcagggtc agtggccaac
    17941 agcagatccg cattgtactt cttggcatac tccataccca gagacatagc ttccttaatt
    18001 tcagggttcg gataaggaca agttgggaaa ttaccgtccg gcagacgctg ttcttccaca
    18061 acggtcacat tgctgtatcc catctctgcc agggtgcggg taacaggcac cagaccggta
    18121 ccattcagag gagaatacac gatagcaaca ttcttgtcca cttcttcgcc aaacaggacg
    18181 gactgcccct tcacttcttc gatgaaagca gtcagaactt ccgactgaat ggatgcaatc
    18241 ttagaagcat cgccatccat ctttacatca gcaaagatgt ccagcttttc gatttctgcc
    18301 agaattgcag tagcagcctc ggtagtaatc tgacagccgt ctgcaccgta taccttgtag
    18361 ccgttatatt tagaagggtt atgagatgcc gtaatcataa caccggcatc tgccttcaga
    18421 taacgagtcg caaaagatac tgtaggaaca ggaagcagtt ctggccacaa gtgcacctga
    18481 ataccatttg cagcaaagat gtctgcggca gtctttgcaa acacatcaga tttgatacgg
    18541 gaatcatagc caaccaccac ggaagcggct tcatagttct tattcagata gtctgccaga
    18601 ccttggcttg ccttacctac ggtgtgtacg ttcatgcgat tagtgcctgc accgatggta
    18661 ccacgcagac caccagtacc gaaagacaaa tttttataga aagagtcctc aatgtccttc
    18721 tcagaatagg aacgcagttc ttctataata tctgcattgg catgattcag ccaacgctca
    18781 tattctactt tataattcat attattatcc tctcacatcc agaaactgaa tcgacccgtg
    18841 aatgctgatt tcagtagaat cggccggcac aaaaaggcag tcccccttat agatgtccaa
    18901 cgattcatta tcaaatcgaa cggtaccaca gccattgaca cacagcaaca cacggaagct
    18961 gattgaatcc gcacgatagt gtaccgtctg tcttctctca gtgttgacaa tcatacgaga
    19021 gacctcgaaa tgcttgcatc tgcaaagcaa ttccgcagct acaccagcac gatattttag
    19081 aacacgaagc ggctgtttcg gttctgacaa ccctttcaag ttcgctactt ccagcgcttt
    19141 gtctacatga agttctctct ttttaccatt tttgtcaaca cggtcataat cgtagagacg
    19201 ataagtcaga ttggaatttt cctgaatttc tgcaattagt gcacccgcac caatcgcatg
    19261 aatcgttccc gcctcaataa agaacacatc attctttttg accggaacct tctgaagata
    19321 acgctcaaca gttccctgag caatcgcttc acggatcaca gcttcttctg ttattttctg
    19381 cagcccatag attaagctgg catccagtac ataccacatc tctgtctttc caagctgccc
    19441 gttttctttt tcaattgcat attcatctgt gggatgtacc tgaacagaca aatccttttt
    19501 cgcatcaatg aatttgatca ggatcggcaa ttctcctttg gtctgcggat gcgttcccag
    19561 aaactctggg tgttcttgca acacctccgt caaggtcatc ccctgatact ctgaccagac
    19621 acaacaaagc tcggtccatc cgggtgcgta gagcattcca agtttccgca agaggagaca
    19681 tctcaattcc ttttgcaaat tcatcattca ggcggttccc ccccacagat aatcctttgc
    19741 ggaaggcttc aataaaaacg gtttctgtat aacgagccct cctccgtttt ttaatactct
    19801 aactcaaatt tctgtttatc tttaacattg atatccttgc caagctgtac ttcaatcagc
    19861 ttcagctcag tatctgccat aatggtatgc cgacagccag cactcatggt gatcacatcg
    19921 ccagccttaa caacctgctc atatccatcc acgatggtct taccagtacc ggccagaacc
    19981 acccacacct cgtcacggtt cttgtggctg tgataattca tggagtgact agcattcaga
    20041 gtaaccttaa tggtcatgct ctctgcttct acatccataa ccttataact accccaagac
    20101 ttctctgcga acatgatctg ctgctcgaac ttgtcaacga aaggcttaat atagctggac
    20161 tgttccttat cggaaaccag aataccttcc cgagatgcac agatgaccac atcatgcaga
    20221 cccatagcca acacaggaac atccagttcg ttcaggatgt gtacgccatc gcaattctca
    20281 ttcataacac ctttaccgat aatggattcc tccatacctt cggtcagagt attccaagtc
    20341 cccagatcct tccacatacc agcaaaacgc tgtacctgaa tcttgtcctc atgctcaaca
    20401 acggcatagt cgaaggaaat cttagtcaga gtatcgtatt tgttgaacag atcctgataa
    20461 tctacaaagt caatcagctg atgtgcacgc tccatgacat acttcagctt gtagacaaac
    20521 acaccaccgt tccacagtgc accctgtgcg atatattcct ttgccacagc ctcagaaggt
    20581 ttttccttga aggtatttac gaaagcagtc tgctctgcgc tctcaggaat gatgtagccg
    20641 tacttctcgg aaggataagt cggttcaata cccatgagca ccagattagc ttcgcctttg
    20701 tcagcctgat cggacagaga tttcagggcc tcaaaatagt catcttctac gtaagggtca
    20761 accgggcaaa caactacgga ctcttctgga tcaatgccca tcacatctac cagataagcg
    20821 gtagccaatg cgattgccgg gaaggtatcg cggcgacaag gctctacaga tacacccaca
    20881 tcctcaccaa gttggttatg gatagcagaa acctgtgtct tagaggttgc aatcgtaaca
    20941 gttgcgtcgt tatctacctt cttaatctgg cggtagacac gctgaaccat ggattcatat
    21001 ccatcttcag ttttgaaaat cttaatgaac tgcttggaac ggatgtcatt agacagcggc
    21061 caaaggcgct taccagaacc gccagacagt aaaacaatat tcataatgat ctctcctttt
    21121 tataagaaag aggctgctgc aatcctcaaa aatcacagca acctcggtaa attagcgttc
    21181 agcacgcatc gggttattca ggaagtcctc gtaggacaga cggatgccat cttccaactc
    21241 agtcttatat gtccatccca gcttggttgc cttggaaaca tccagcagct tacgaggtgt
    21301 accgttcggc ttgctggtat cccacagaat ctcgccttcg taaccaataa cctttgctac
    21361 catctcggtc agttccttga tagacagttc cttgccagta cctgcattaa cagtctcgtc
    21421 accgctatag ttattcatca ggaacacaca caggtttgcc agatcgtcaa catataggaa
    21481 ttcgcgcaga ggagaaccat caccccagca ggtaacagta ggcagacctg cttccttagc
    21541 ctcatggaag cgacgaatca aagcggggag cacatgactg tgagtaggat gatagttgtc
    21601 gttaggtcca tacaggttag taggcataac agagatatag tcagtaccgt actgcttgtt
    21661 tagaaactca cagtacttca ggccagaaat ctttgccagt gcataagcct cgttggtctt
    21721 ttccagctca cttgtcagca gacagctttc cggcatcggc tgcggtgcca tacgcggata
    21781 gatacaggaa gaaccgagga actgtaactt cttacagcca ttctcccatg cggagttgat
    21841 gacgttcatt tccagaatca tgttttcata catgaagtct gccagagcgt tctggtttgc
    21901 gataataccg ccaacctttg cagcagcgag aaatacataa tccggctttt cctgtgcgaa
    21961 aaatgcttca acagcgtcct gacggcacag gtcaagctcc ttatgggtgc gggtgataat
    22021 attgttgtag tcctgacggt tcagctcgcg cacgattgcg gaaccagcca tgccacgatg
    22081 accggctacg tagatttttg cgtctttttc catcataata atgcttgctc ctttctaaat
    22141 ttagagcatc tctcattgca tgagagaaat caatttgtct gcgatttcgc tcgcagcatc
    22201 ataaaatgta tcaaaatttg aggtgtctag ctgtttgagg tcctcaatca cccgctctac
    22261 gcggtggagg ttttccggtg tgacggaaat tgccagaccc agtttttgca atttacaaat
    22321 agttgttcta tcttccaaaa ctgtatcgcg ggcgaacagt gccatcggac gctgtgcgag
    22381 aatacactcc gcaacagttc cccatccagc ctttgtaata acgtaatctg ccgccgctat
    22441 atagtcctgt gtattggggg tgctgttaga aataacggtt acgttttctc ccacaagcgg
    22501 aacacctagc gttgtaatga aatcatacgg cgcgtgactg acatcaatcg gctgtttgaa
    22561 ccgcgcggac ataccgagtg cgacaaatac aggcggtttt tcatgctgtg atttaatgcg
    22621 ttgcacttcg tcgttatgaa tcggacgcgc cacaacggaa gtcggtgttt tttcgctgtt
    22681 ttggagaaat tccaacattt cttcgttatt tagcgcataa agcatggtgt gctgaatttt
    22741 accgtaacgc ttggcatatt ctttccaaat atgttcgggt aaaaattcgc gatacagctc
    22801 tgtccaagtg aagtttccta catacaggaa aggtactcct gccatatcgc aggcatccat
    22861 tgcccagatt ggcatatcgc aaagcactgc gctgacagct tctcgcttga gccattcggc
    22921 ttctgtcttt gccaaagaag gaacctttgc caaaaaatat tcacagatct cggtcagctt
    22981 acccgtgtcc accagtaggg tgccctcacg gttaatcaga ccgatatctg tgtttattgg
    23041 acgatagcgc acgcggtcta tcagctcttt gggcagttcc tgctccaaat tgcgctttgc
    23101 aaaatccaga tgatttgcgc cgcaaaccag tgtaatcttc gcttcgcatc ggcagagtgt
    23161 tgccataata atgggcagat tccgcgcgat atgtccgaag ccgtgactgg aaagatagaa
    23221 acagatatgt ttattcaatg tcagcttact tgactgcgtt cttcattgca gcttcgcgct
    23281 ttgccaattc acggtcatgc tttgccatga tgttaaccag ttcctcgtaa gaggtcttct
    23341 gcggattcca accgagaacg gtctttgcct tagtcgggtc gccccacagg ttgtcaacgt
    23401 cagtcggacg gaaccactgt ggatttacac aaacgagcat cttgccggtt tcaacatcgt
    23461 agcccttttc atcaatgcca gtgccttccc aacgaatggt catgccattt gctgcgaatg
    23521 ccttctcggt gaagtcacga acagtgtgct g
//
LOCUS       DAYYEF010000044        22635 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000044 DAYYEF010000000
VERSION     DAYYEF010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.045"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(225..1112)
                     /locus_tag="ACHA1B_001963"
     CDS             complement(225..1112)
                     /locus_tag="ACHA1B_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702714.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1109..1978)
                     /locus_tag="ACHA1B_001964"
     CDS             complement(1109..1978)
                     /locus_tag="ACHA1B_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702715.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2115..3401)
                     /locus_tag="ACHA1B_001965"
     CDS             complement(2115..3401)
                     /locus_tag="ACHA1B_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8702716.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3674..4252
                     /locus_tag="ACHA1B_001966"
     CDS             3674..4252
                     /locus_tag="ACHA1B_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFM8702717.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4252..5181
                     /locus_tag="ACHA1B_001967"
     CDS             4252..5181
                     /locus_tag="ACHA1B_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702718.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5178..6914
                     /locus_tag="ACHA1B_001968"
     CDS             5178..6914
                     /locus_tag="ACHA1B_001968"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_function: GO:0004673 - protein histidine kinase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HFM8702719.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6977..7813)
                     /gene="pheA"
                     /locus_tag="ACHA1B_001969"
     CDS             complement(6977..7813)
                     /gene="pheA"
                     /locus_tag="ACHA1B_001969"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HFM8702720.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7810..8319)
                     /locus_tag="ACHA1B_001970"
     CDS             complement(7810..8319)
                     /locus_tag="ACHA1B_001970"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004765 - shikimate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HFM8702721.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8312..9607)
                     /gene="aroA"
                     /locus_tag="ACHA1B_001971"
     CDS             complement(8312..9607)
                     /gene="aroA"
                     /locus_tag="ACHA1B_001971"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HFM8702722.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9620..10711)
                     /locus_tag="ACHA1B_001972"
     CDS             complement(9620..10711)
                     /locus_tag="ACHA1B_001972"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HFM8702723.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10728..11894)
                     /gene="aroC"
                     /locus_tag="ACHA1B_001973"
     CDS             complement(10728..11894)
                     /gene="aroC"
                     /locus_tag="ACHA1B_001973"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004107 - chorismate synthase activity
                     [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HFM8702724.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11896..12960)
                     /gene="aroB"
                     /locus_tag="ACHA1B_001974"
     CDS             complement(11896..12960)
                     /gene="aroB"
                     /locus_tag="ACHA1B_001974"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA];
                     GO_process: GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HFM8702725.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12993..14015)
                     /gene="aroF"
                     /locus_tag="ACHA1B_001975"
     CDS             complement(12993..14015)
                     /gene="aroF"
                     /locus_tag="ACHA1B_001975"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HFM8702726.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14674..15648)
                     /locus_tag="ACHA1B_001976"
     CDS             complement(14674..15648)
                     /locus_tag="ACHA1B_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HFM8702727.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15629..17512)
                     /locus_tag="ACHA1B_001977"
     CDS             complement(15629..17512)
                     /locus_tag="ACHA1B_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HFM8702728.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17530..19755)
                     /locus_tag="ACHA1B_001978"
     CDS             complement(17530..19755)
                     /locus_tag="ACHA1B_001978"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HFM8702729.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19870..20904
                     /locus_tag="ACHA1B_001979"
     CDS             19870..20904
                     /locus_tag="ACHA1B_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8702730.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20971..21984)
                     /locus_tag="ACHA1B_001980"
     CDS             complement(20971..21984)
                     /locus_tag="ACHA1B_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM8702731.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22062..22250)
                     /locus_tag="ACHA1B_001981"
     CDS             complement(22062..22250)
                     /locus_tag="ACHA1B_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HFM8702732.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         6448 a         4863 c         4095 g         7229 t
ORIGIN      
        1 caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt tttagcatgt
       61 atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga gcacaaactt
      121 aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa agtatctttt
      181 tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt tacagagccg
      241 atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt tggtaaagta
      301 gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc acccatagca
      361 gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa gggccataaa
      421 taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt atttttagcc
      481 gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa tcgagcggct
      541 tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat caaaaaagca
      601 gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac cgttccgttc
      661 aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac catcatcgat
      721 agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc aaatccatat
      781 cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat catcgctgaa
      841 ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa attgatgatc
      901 aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt cgtcattccc
      961 aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa tgctgtatac
     1021 tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac gttggggcgt
     1081 tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact ttcgtttgga
     1141 ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc gcatatccaa
     1201 aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg gtcgttgcat
     1261 ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat gtcccgatcg
     1321 tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc actttgataa
     1381 actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc gaatcaatat
     1441 tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa gtgatcgaaa
     1501 gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt gtgtcaatca
     1561 taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga cttttcatga
     1621 tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt cgaaacaacc
     1681 ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct agaaacaaca
     1741 tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt ttaaaagttg
     1801 catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg acagggggac
     1861 cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg attgatatca
     1921 aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc tgcttcattc
     1981 ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga caatatctgt
     2041 aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga agaaattcac
     2101 ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt atctgctagt
     2161 accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac gactgcttca
     2221 attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca tgttgaaaaa
     2281 tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc ttcttgttca
     2341 ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc catcagttct
     2401 tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc agctactcct
     2461 ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg cagattttct
     2521 ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc tccttggatc
     2581 gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg tatcgcagtt
     2641 actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag agtggcaaac
     2701 aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc cccatcttca
     2761 gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag gtcagaagga
     2821 ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac ttgaatatac
     2881 tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc catcagatcc
     2941 gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat tttatctcct
     3001 actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat agcagacaaa
     3061 ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc ttcaatcaag
     3121 acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag tttctgaacg
     3181 atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc ataaactttt
     3241 tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac agtgactttt
     3301 tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc tgatgctgcc
     3361 gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg ctccttttcc
     3421 atccattagt tgtttacgtt tgctacattc atcataccaa aatttgaaaa cggtttcttt
     3481 attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa tcaactatga
     3541 caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt ctttaaaata
     3601 aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga ctattcttaa
     3661 ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga cgattttaga
     3721 tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag ggactttttc
     3781 cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg tggtcacaga
     3841 tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac agcaacaacc
     3901 tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta aagattcttt
     3961 taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt tttttctaaa
     4021 ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc caatcaccaa
     4081 tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa ctcgtccatt
     4141 gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga aaaacggcca
     4201 ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt gatggatagc
     4261 gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg ctatgtaatc
     4321 aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca agaagttttt
     4381 ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa tgaaatattc
     4441 caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa gaaccttgct
     4501 tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag tagttattta
     4561 acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa tttcttcacg
     4621 acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat caatcgtttc
     4681 tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact ttctttgctc
     4741 aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt ttctattctt
     4801 gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa agacaatttc
     4861 gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga aatcaattta
     4921 caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat ctttactgaa
     4981 aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa agccaagctc
     5041 tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg ctataccgaa
     5101 ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc tcaataccgt
     5161 aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt gccaaacttc
     5221 tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg tttatttatc
     5281 atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg gtactaaaaa
     5341 agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta gccgcttttg
     5401 attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat atggaacagc
     5461 ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc catccaatga
     5521 tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga aacgacatgc
     5581 tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga gtgaatgaac
     5641 gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc gataagaaag
     5701 cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt tacggatatg
     5761 ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta gtaaatcctg
     5821 agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca aatgaagaaa
     5881 atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa acaacgattt
     5941 caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca ttactcagtc
     6001 aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt attttgtata
     6061 atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat cgacacacaa
     6121 aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc ttaaaagcta
     6181 ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc aatcaattgc
     6241 taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag aaacgttcgc
     6301 ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat acgctgacta
     6361 gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga atcgacagtt
     6421 tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca gtcaaggaag
     6481 aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc gaaagaatct
     6541 cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat atgatccttc
     6601 aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa ggattcatca
     6661 cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat aacggcgatg
     6721 gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc ggcatcagcc
     6781 atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg atccaatcag
     6841 tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa aatcaatcag
     6901 aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta aataaatcaa
     6961 tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga taacagccca
     7021 atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct actaatgtca
     7081 ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta gttttcaatg
     7141 gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc agcattttat
     7201 gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt actggagctg
     7261 actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg ttcaactcat
     7321 tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt tctaatgaag
     7381 caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca gcagttgttg
     7441 attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt tgtgattgtg
     7501 ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg cctaaaagct
     7561 gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt ttggaaagaa
     7621 gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg acagccagat
     7681 cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac gcagtcaatt
     7741 gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct ggccctagat
     7801 agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct tttctggtgt
     7861 ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa gtcgttgtgc
     7921 caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa tagacgtttc
     7981 atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa gaacaatcgg
     8041 ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac cagtcgcgat
     8101 aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc gaaagctttt
     8161 ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct caatctttgt
     8221 atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga ttgttgtttt
     8281 tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct cctgacacaa
     8341 gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca gctccttcta
     8401 gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg attcgatgat
     8461 cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg atcagaccgt
     8521 ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc gcatcaattc
     8581 tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt ccttctgctt
     8641 gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg atttctccac
     8701 caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat tggttctgtt
     8761 cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct aagataccag
     8821 ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga acaagaagtc
     8881 ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc tgttgaccag
     8941 ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc cttccgccaa
     9001 attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg attacggatg
     9061 tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca ctggctacag
     9121 gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt ggtagatact
     9181 ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc atcactcgcc
     9241 ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa ggctgtccag
     9301 ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca attgattcgg
     9361 ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct tcctcttctt
     9421 cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct tctgcgcgca
     9481 aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg ctgcgatggg
     9541 aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt tgttgtaata
     9601 attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta gacataatga
     9661 ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt attcctaaaa
     9721 tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct tttccgatca
     9781 gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat aaatcaaaaa
     9841 aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct tttgcccgat
     9901 tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct atttgtgtca
     9961 tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc aacaaaatat
    10021 ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag cctcctgctg
    10081 ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg actaagccag
    10141 ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt tctcttgctg
    10201 taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt tcaacatctt
    10261 ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt ttagcatctg
    10321 ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca aaccgaagat
    10381 ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc gtaatgatga
    10441 cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt gtacggacgg
    10501 gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca cttgcaacgt
    10561 aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta tcccaaccaa
    10621 ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca ccaatcagtc
    10681 caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta gtaatgtttc
    10741 aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc acttgggaat
    10801 tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac gacgctagct
    10861 gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc ttttgtatcg
    10921 atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac cccgcgaatg
    10981 acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt ggtacgtcgg
    11041 aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc tggtaatgaa
    11101 ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact aaccacagct
    11161 tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa tccagctgga
    11221 acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt ctttgtctga
    11281 tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac ttctgacgct
    11341 tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc ttggattcca
    11401 ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat tttcttggca
    11461 attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc aagcacattc
    11521 cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc tggacgcgga
    11581 cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga catgacagtt
    11641 gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc aattgttttg
    11701 ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat ccttcctcct
    11761 ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc tgacagaggt
    11821 aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga ttctcccgca
    11881 gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg tgggaacagg
    11941 aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc ttcctcttgc
    12001 tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat cgtacgtaat
    12061 cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag ttggagacaa
    12121 gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc cttctccatg
    12181 actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat gaccaaaatt
    12241 taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc gtttgatttc
    12301 caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt ctttcagctc
    12361 gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga tttcagcgat
    12421 tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa tcaatacacc
    12481 agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga ctgctgtctt
    12541 cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa cgaaatggat
    12601 cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc ctccaccaag
    12661 tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt ataactcagc
    12721 tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga ctggttcaaa
    12781 attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa cgtttgtatc
    12841 agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc cagcctgttc
    12901 tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta cagtaagcat
    12961 tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat cttttccatt
    13021 gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc attcaacgat
    13081 tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat catgccatct
    13141 gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat tcctgtacca
    13201 tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg gacagcactt
    13261 aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc gataaaaatg
    13321 acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc attgatcgta
    13381 ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc agatagcagt
    13441 ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc agccaccata
    13501 tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc atcagccgct
    13561 tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg agaagtacgt
    13621 ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat tcgcgcacat
    13681 tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac gaaactgccg
    13741 tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa ttctcgagaa
    13801 gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata gcgtgtaaat
    13861 gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg ttctgttcct
    13921 tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt ttttatttgt
    13981 tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt cttttgttta
    14041 cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt aattcctact
    14101 aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat gacccagata
    14161 atcaacaaaa aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc ttcaacgagc
    14221 cttaaaaagc gctgcaaaaa tataaaatag ccactataga tgaatttctc tacgtggctg
    14281 taagtcgtgt ttaaaaatct ttagccatca tagatacaaa cctggtttgt ttgtacccac
    14341 gaagtcatga atacaaacct atctaaaata gctaaagtaa tacgtattca gttttgtaag
    14401 ttttctagat ttcataaaaa atcgctccaa actgatgtaa gaattgtacc tagtatagac
    14461 ataaaaaaat cgactgtcaa tcatttttat gaaacttttt ttaattttct gatagttaac
    14521 tttgtttttc agaaaaataa caattggttt tattgaagaa aatagtcatg aacaaaagta
    14581 tctgagaact tttttactct cttgttcatg acatatagaa taaagcagct ttgtcttgta
    14641 aactccgttt ttcaaataat aatctaaaga ttgctactga ataataaagc cgatttcatg
    14701 gtcctcttcg ctgctgattc ggtaaggtga ctcaacatcc gctccccagc tattgatacc
    14761 cccgactcct cttacttttg caaaaatcgt aagaaccgtt cgtctttctg gcggtagttc
    14821 ttctatatgt gttgcctgtt ccagttcttc tgctttgaat ggtaaagcgg aaaaagcaaa
    14881 tggcgtatcc tgctgttcaa atcgcaacga aaaatcttct tgatctttat ccgtattatc
    14941 caacgtttga tttcttgtta gttctaccca tttcgtttcc atatgcatgc cgcattcttg
    15001 gggaacaagg tatggggaaa cggggagtcc tgccacttta taaatacctt cgacaccacc
    15061 agccatccga tccggatatg tttcccctga taggccttca tactcaaaaa attttgcttt
    15121 cgttggcata atgaacctta aacccaatgc gggtaattcc ggtaatcctt tttgtccata
    15181 ataatgcata ttgacaagca ttttaccctc tccagcgatt tggtaggaaa ttgtcacttg
    15241 ggtttttggt actgtgttga tttccagtgt aaaaatgatt tcaaccgttt cagcgtattc
    15301 attacttgaa tattgattat ttactggagc aatcggcaaa tcgatctttt tattgtccac
    15361 cagtacttct atttctttga cttttggata caatccggct cctaaccaca taccggattt
    15421 aaatccaaat ccgctacctc tgtcattatc ggtcgttgct cgccaaaaaa ctggaagtgt
    15481 ttcccggtat agccattctt ttccgttttt attgagcgat tccagtccgc ctcttgtata
    15541 agaaaaaata taatgcgtat tccccgattt gacacctaat gtacagtcgc cgaagacgat
    15601 tgcaactttt tccgtatcca tatgactttt atttactgta tttttcataa taatatctta
    15661 cctcctgcat ggcgggtttt tcttgtccat ctgcaaaaac gatcccattc cctgagaatt
    15721 catagtcact tggtttatcg tcaaagtcac cgccatagcg catcacttct ctgcctgtga
    15781 ttggatcagt cacttggatc gcctgatctt taaaatccca tatatagcct ccttggtaca
    15841 tttcataacg atcaagcaac gtcatgtaag aatccattcc acctaacgaa ttccccatgt
    15901 catgcatata ttcacataag atgaacggtt tttccgcttt attttcaagg tagtcaatga
    15961 tctcttctgg tggcgcatac atgcagcttt ttacatctga aatcgaatct tcgaatgctg
    16021 gatttggaaa attcccttca taatggacaa gtcgatcggg gtctactttt ttgaagtaat
    16081 cgttcatttg tcgaatgttt tcttccgcat aagattcatt tccaagagac caaaaaagaa
    16141 tacttggatg gttttttaat gtttcgaaat tcgtttttgc tcgatcaaga acagccgcct
    16201 gccactgagg tactgcacct ggtacgttgt aagaaggctc aaatgcgccc attttttgcc
    16261 atgagccatg ggattcgagg ttcgtttccg ccatcacatg gattcctgct tggtcgcata
    16321 aataatacca agtgatctgg ttggggtaat gagatgtccg tacgccgttg atctttgcat
    16381 tttttatgat agccaaatct ttttccatat cttctatagt gatggcgcgt ccttttttcg
    16441 gatgccactc atgtcgattt accccgttga taatcatccg ttttccattg aagtagatga
    16501 ttttatcttt gatttcgatt ttacgaaaac cgaaggaata gtcaatatac tccgttactc
    16561 ttttttcttc gtctatcgtc tccaattcaa gcttatataa attgggctga aaatgccccc
    16621 acagtgccac attttcaaat ccatcgatgc gaatcgtcat ttgctctttt aacggatatt
    16681 gctgttgata gatttccttc ccatcaggat ctagtatcgc tacattcagc tgactgtttt
    16741 tggctacttg ctcaaaagac aaatctactt caagtttgcc attttgacat ttgtcatcta
    16801 agcgaggttt gatccaaaga tcttctaaat ggttttgtcc tcgagcaact aagaagacat
    16861 ctctgaagat cccaaaaaat cggaaaaagt cctgatcttc caagaatgca gctgtacttc
    16921 ttttgtaaac ctccacagct agaatatttt cttcttccaa ataaggtgtt aaatcaaatt
    16981 cagacggagt gaacgaatct tcggcatacc cgataaaatg accattcaac caaataaaca
    17041 ttgcttgttc tacaccagca aaatgaatcg agatttgttt tccctttaga ccttcttcta
    17101 atcgaaaagt cgtcaaatac gaaccaaccg gattgtcttt agcagctgaa aagatccctt
    17161 ccgcctcttt ctcagggctt gtcgtgaaag ggggacggcg aaatacatgt ccctcccacg
    17221 gatacatcgt attgatgtaa tggatcttgt cataatttgc taattcaata tgactaggaa
    17281 cagtgatttc atcaaaagaa caggcatcaa aatctttttt ataaaatgtt tttggtcgta
    17341 ccgaaggatt tggcgaataa caaaaacgcc atgatccatt taaagactgt ttaagggagg
    17401 atgtggtttc tacttcttcc cttgttgcat aacaaacatg atcgctatgt gcatttgatt
    17461 ggttcactct aaaaacttgt ggatcatcta accattttat atttgctttc atactttttt
    17521 ccttctctct cataactttt tgaaatgaag cagttctgtt tggaaatcac cttgaaaatc
    17581 ggggaagtaa agtccaactg tcatcaattc ggcccccgaa aatatccgct tcgaggtctg
    17641 ttcctgataa agtgcctcat catctaaccc catcagatat acttcatgga acgctggttg
    17701 agctgaagct agtatcctcc ctaaaaacac aatagcttca tcttgtttag gagacacaaa
    17761 catccatgcg gcaatatttt cttcaaaagg actcgccaaa cgataataat ggccatactg
    17821 gatcaccgga cgaatcgttt gataggatat aatttggtct tttacttgct ttttttcttc
    17881 aggagacagc tttgtcaaat ccagttcata accaaaaaca gcgctcatag ctgtttctcc
    17941 tcttgttttc aacgaagtag atctgtcggt ctgatgattt ggtacagctg atacatgagc
    18001 tgtgatggac gaaatcggat aagcaaggct tgttccatat tggattttca tacgctccac
    18061 tgcatccgtg ttatcacttg tccatgactg cggcatataa taaataaacc cggcatcaaa
    18121 ccgtccacct ccaccagaac agccttccca taagatttcc ggataatcag ttgtcaaatg
    18181 ttcaagtagt tcataaagcc cgagcatata acgatgcgct acttctcctt gtctctgtgg
    18241 gtcaagggta atcgaataga catctgaaag cgaacggttc atatcccatt tgatgtagtc
    18301 aagaggaatc gtatctaaaa tctttctcat ttgtttctca atcgtctgcc gaacatctaa
    18361 ccttgtaaaa tccagtacat gttgtgatct ggaagcagaa ggcattctac ctggctcctg
    18421 cataagaaaa tcaggatgtg ttcgatacag ttcagaatca accgagatca tttcaggttc
    18481 aaaccataaa ccaaatttca atcctttgct atgagcataa tctgctattt cacgtaatcc
    18541 atttgtcaac ttgccttcat actcgaacca gtctcctaat gaagaattgt ccgcatctct
    18601 ttttccaaac cagccatcat ctaatacgaa catttcgatg cctagctcct ttgcttcatc
    18661 aatgatcgcc ttgatttttt cactattgaa gtcaaagtaa gtggcttccc agttattgac
    18721 cagaatcggc cgttcagcaa attgatgacg acctcttgcg attctttcac gtagcaactc
    18781 atggtggatc tgactcattt tgttcaatcc ctgacttgag taagaaagga tcatttcagg
    18841 tgtttgaaaa gactggcctg cattcaattc ccacgaaaaa cgatggctgt tgatcccacc
    18901 gacgactctc aattgattga tctgatcttt ttcaagttcg aaagaatggt tgccggaata
    18961 aacaaattga agtccgatcg cttctccagt attttctgtc gtatgatgat gaactaaagc
    19021 aataaagtta ttcatatggt gactgctcgt tcctcgacgg ctttcaaata cttttgttcc
    19081 agataaaaca gattgccgtg aaatctgtct ttcattgaca tgtgctcctg gcaaagcaat
    19141 gacttcatca aatcgcctag tatgggcaaa gtctagctgg aaactagccg ctttttctag
    19201 tttgattgtt tctccggttt catttcttat ctttacagat cgtgtgatca ctgctctatc
    19261 agtaaatatg gtatagaaca aatcgaaata aatcgctgtt tctctatcct taagtgaaat
    19321 caccaacgtt tgtgcctctg acttgtccat cacataagtt tgaggcaagc cttcgatctc
    19381 tggcttccca tctgtaatat aatggctgtc atatctcaga tccagtaagt ctgatccatt
    19441 cttgcgctga atgatcgatg cgggcgttcg aaagtccatg ctgccatgag aagagtattc
    19501 ttgcggtagt gtatctttcg acagagaccg gtcaggattt aagggaacat ttcctgaaaa
    19561 tccacgatct cttcggggat aatttttatt gtctttgtac tgcttgactg gtttgccaaa
    19621 ataaatatgc gccaatacat tgctttcttc tatctttatc agataagaaa gaaatgtatt
    19681 tcgtaaatgg aagactcggc tcttttcatc aaataagatg aaatttttat ctgtttttct
    19741 atgcgtaata tccatcattt cactcccaac aaaacggaaa ccgtttactt ttttttataa
    19801 ttcctgtata ctgtttacta aacaattttg tcaataaaaa ttttttattt ttttgaggag
    19861 tgtgtaaaaa tggttggaat tagagatgtc gcacgaaagg caaatgtctc tcctgctaca
    19921 gtttcccgtg tgttgaataa cgatcagacg atccatgtgg ctcagactac tcggcaacgg
    19981 atagtagagg cagctgctgc gttggattat gacatcagta ctcgtaaata tatcaaaaag
    20041 agaatgcctt cgattggtgt gatctctacg atcggcaaag cgagcgaaga acaggatatc
    20101 tattacaaac atttgcgagt agggatggaa gaagaagctc gacgtctgca tttagggatg
    20161 aatcgaatct ataatctatc tgataatcct aaacaatggg aagatctaga tcagttaggt
    20221 gcggtgatcg ttgttgggac tgttacgaaa gaatcgatta ccgccttgtt aaaacaaaac
    20281 atgcaaatag tcgtcgtgga taaccctgac atccagcaag aggtcgatat ggtgtatgca
    20341 gatcttgaac ggatgactaa aaccgtactg gaattgttct tagaaaatgg tcataaaaga
    20401 atagcctata tcgggggata taaagtcgat atggatgaat tcggtgggaa gcagatttct
    20461 ataaatgaaa agaggatgcg tgcctatcag cattttatga tcgatcatca cttagaaaaa
    20521 tatatgtctt atcatctagg tggctggaca gaaaaacaag gtgaggtact tgcgactaat
    20581 ctattagaaa atgaatcccc tcttcctact gccattcttg tcgggagcga tccaatggca
    20641 attggtgtct atcgggcatt gaaacaaaaa aatatccaaa ttggagaaga gattgttgta
    20701 gcaagctttg ataatatcga gacaatcgca aacctctccc ctggcttgac cagtgttcaa
    20761 atcaatgcga aatcaattgg gcaagcagct gttcgaatgg cattggagcg aattgacggt
    20821 atacgggacg aaccaatcat tttgacttat cctgcacgat tgattgttag ggaaagtttt
    20881 atcccaagaa caaaaaggta ttgaaagaga ggttgtgaaa agccgcttcg tttcttcata
    20941 ctcaaaacga aacggctttt tcacaacctc ttacttatac ttattcacaa aatccaatgt
    21001 ctgctggtaa caattttgcg attcttttag cgtgtaatca aattggtatt catgggtaat
    21061 ctcttttttt gtatctgtat aaaacaagga ttgcacgggt acctttaatt ctgtcaaccg
    21121 attttctaat gcttgacctt gctcctggaa tgagtatgca tttccgtcag ttatatacgt
    21181 tggcggaaat tccttagaaa catggtcagc cacactagct tctttcaatt gctcactcgt
    21241 tttccaatct tttgttccaa tcaacgacca cgcaacggtt ttgacgaaaa acttcataaa
    21301 tcgatcatcc gaatgctgct gtgctgttag cttcaaatca acaggtccgc aataagaaat
    21361 ggttcctttc agactatctt ttggaagtag ctgtttgatt ttcatttgtt tagcatacgc
    21421 atcattcgtt tgtatagctg catattgcaa tgcgatttgt gaacctgcac tatctccacc
    21481 aaaaaataat tgttccatgt ctagcaattt gtcgtctttt tcttcagcta ataaatcttt
    21541 gatcagttca ttcacttgaa gaacttgatt agggtattct gaatcaggcg ctaattcata
    21601 attcatcgca accactgcga tgttggcgtc tgaaactaat tttgtcgcaa attctttgac
    21661 acccgattta tctccgccga cgaatcctcc accatgtacc caaaatagaa caggaacagg
    21721 ccccttgctg ttttttggat agtagatgtc ataagtattc tctttatact tggactcata
    21781 cgtcaaatct gtttttttcg ccacgttttt ttctgcttga tcgaacgttt ttttatcagt
    21841 gatttgaaca gtatttgaaa acatatggtt gatcaagaat gctccaggtc tgggggaaag
    21901 ctggaaggca agaaagattg caaacgcgat cccaagaatg attccgaaga accatccgat
    21961 aaatttaaga attttctttt tcataaggct ccctcagtag ttagtattaa gcattctgat
    22021 tataccatag tgttatttcc tatcaagctc tcctagatga tttaatgatt ttccccaaac
    22081 ttcttctgca atgcttttga caaaagaaat tttttccatt gttcttcaaa caaaacattt
    22141 tcttcttctg ttgaagcaaa tccacattga ggacttaagc acaaacgatc caaaggcaga
    22201 tatcgtgtcg cttcgtagat ccggtcaatc acttgctggt gctcttccat ttcgccattt
    22261 ttcgttacag tcaaaatcta agacaactaa tttatcttca gagactttct ctaaaagaac
    22321 aaaactccca gcacgttcac tatcgtattc taaataatag gcacggacat tttcttgagt
    22381 aaaataatgg gtctgctacg tcgtcatccc ccctgatgcc gccaaaatcg aataataatt
    22441 tccgcgtcaa acatgtatat ttagtgttga atcatttgag aatatgaaaa taaaaatctt
    22501 tttgatcaat cagttaatca aattgaaata acgaaaaatc tgagacagaa tgacgttcat
    22561 tctgacccag atttgatttt gcacaactca acagtcctta ttggcaaatc gccaaaataa
    22621 tgtagactaa ctaaa
//
LOCUS       DAYYEF010000045        21688 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000045 DAYYEF010000000
VERSION     DAYYEF010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.047"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(41..967)
                     /locus_tag="ACHA1B_001982"
     CDS             complement(41..967)
                     /locus_tag="ACHA1B_001982"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0016597 - amino acid binding [Evidence
                     IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HFM8702733.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            complement(980..2263)
                     /locus_tag="ACHA1B_001983"
     CDS             complement(980..2263)
                     /locus_tag="ACHA1B_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="solute carrier family 23 protein"
                     /protein_id="HFM8702734.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            complement(2277..2816)
                     /gene="pyrR"
                     /locus_tag="ACHA1B_001984"
     CDS             complement(2277..2816)
                     /gene="pyrR"
                     /locus_tag="ACHA1B_001984"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HFM8702735.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            complement(3051..3962)
                     /locus_tag="ACHA1B_001985"
     CDS             complement(3051..3962)
                     /locus_tag="ACHA1B_001985"
                     /EC_number="5.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HFM8702736.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            complement(3959..4423)
                     /gene="lspA"
                     /locus_tag="ACHA1B_001986"
     CDS             complement(3959..4423)
                     /gene="lspA"
                     /locus_tag="ACHA1B_001986"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HFM8702737.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            complement(4428..5126)
                     /locus_tag="ACHA1B_001987"
     CDS             complement(4428..5126)
                     /locus_tag="ACHA1B_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HFM8702738.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            complement(5113..5499)
                     /locus_tag="ACHA1B_001988"
     CDS             complement(5113..5499)
                     /locus_tag="ACHA1B_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702739.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            complement(5646..7316)
                     /locus_tag="ACHA1B_001989"
     CDS             complement(5646..7316)
                     /locus_tag="ACHA1B_001989"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004329 - formate-tetrahydrofolate ligase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HFM8702740.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            7499..7732
                     /locus_tag="ACHA1B_001990"
     CDS             7499..7732
                     /locus_tag="ACHA1B_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFM8702741.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            complement(7831..8262)
                     /locus_tag="ACHA1B_001991"
     CDS             complement(7831..8262)
                     /locus_tag="ACHA1B_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HFM8702742.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            8341..8754
                     /locus_tag="ACHA1B_001992"
     CDS             8341..8754
                     /locus_tag="ACHA1B_001992"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HFM8702743.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            complement(8792..9940)
                     /locus_tag="ACHA1B_001993"
     CDS             complement(8792..9940)
                     /locus_tag="ACHA1B_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFM8702744.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(10062..10658)
                     /locus_tag="ACHA1B_001994"
     CDS             complement(10062..10658)
                     /locus_tag="ACHA1B_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HFM8702745.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            complement(10858..13500)
                     /gene="alaS"
                     /locus_tag="ACHA1B_001995"
     CDS             complement(10858..13500)
                     /gene="alaS"
                     /locus_tag="ACHA1B_001995"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004813 - alanine-tRNA ligase activity
                     [Evidence IEA];
                     GO_process: GO:0006419 - alanyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HFM8702746.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            13888..14319
                     /locus_tag="ACHA1B_001996"
     CDS             13888..14319
                     /locus_tag="ACHA1B_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8702747.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            complement(14364..15713)
                     /locus_tag="ACHA1B_001997"
     CDS             complement(14364..15713)
                     /locus_tag="ACHA1B_001997"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004386 - helicase activity [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HFM8702748.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(15783..16946)
                     /locus_tag="ACHA1B_001998"
     CDS             complement(15783..16946)
                     /locus_tag="ACHA1B_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HFM8702749.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            17075..17398
                     /locus_tag="ACHA1B_001999"
     CDS             17075..17398
                     /locus_tag="ACHA1B_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702750.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            complement(17581..18930)
                     /locus_tag="ACHA1B_002000"
     CDS             complement(17581..18930)
                     /locus_tag="ACHA1B_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HFM8702751.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(18999..19952)
                     /locus_tag="ACHA1B_002001"
     CDS             complement(18999..19952)
                     /locus_tag="ACHA1B_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HFM8702752.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            complement(20054..21244)
                     /locus_tag="ACHA1B_002002"
     CDS             complement(20054..21244)
                     /locus_tag="ACHA1B_002002"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HFM8702753.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            complement(21444..>21688)
                     /locus_tag="ACHA1B_002003"
     CDS             complement(21444..>21688)
                     /locus_tag="ACHA1B_002003"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702754.1"
                     /translation="RKNRTVTRLLSQSFFRIQQVKLLRNIQRVKLKIADKRRWKFYVF
                     LLVYAINKLNIQNTIDFNERASINGCVVFICPGRVK"
BASE COUNT         6250 a         4645 c         3752 g         7041 t
ORIGIN      
        1 cgtttttaat gagtgttttc attttttcat cctcctataa ttacgctttt ccatttagca
       61 ctgcttctaa gattgccatt ctgacgaata ctccattgct catttgctga acgatccgcg
      121 actgtaatcc ttccactaat gaatcagcta attctacatc acggttaact ggtgctgggt
      181 gcataatgat tgcatgtttt tgcaacttct tcgcacgctc aactgttaac ccatgttcct
      241 gatggtagcc ttcttttgag aaactttctt ttccatcatg gcgttcgtgt tgcacccgaa
      301 gcatcatcat gacatcaact tgatctagta gttcatccaa tggcatataa tgtccgtaca
      361 cttcgaattc atcgtcgtac cattctctag gacctgagaa gaatacttgt gcgcctagac
      421 gttttaacat ctgcatattg gatttagcta cgcgagagtg agtgatatca cctacgatgg
      481 caactttcag accttcaaaa tgaccaaatt cttcataaat ggtcatcaaa tcaagcaagc
      541 attgggttgg atgctgtccg cttccgtctc ctccattgat aatcgaacac tggattgttt
      601 tactttgtat cagttcgtca taatagttct catcaccatg acggataacc gctacgtcta
      661 cgcctaatgc tgacatcgtc agtactgtat cgtatagtgt ttcccctttt tggacagagc
      721 ttgtgcttgc ttcaaattca atcacttcta gccctagttt tttctccgct acatcgaagc
      781 ttttatgtgt gcgagtacta ttttcgaaaa agaggtttgt agcaaagtac tggcgctttt
      841 gcggagtcca attagcacct tgcttgaatt cctgccctct gcggatcaag cccataactt
      901 cttgatcagt aagtgcctca acggtcaata aatgctttaa gctgatacgt tctgatttga
      961 tgatcataat gtttcctcct tagttttctt cgcttcgtga agtttctggt aagataagat
     1021 ttaaaatgat gccaagtaca gttgctaatg ccattgccga caatgtaaat gtgcctactt
     1081 caaagacgag tccgccaatt cctactacta agataactga agcaatcaac agatttttct
     1141 ttttatcaaa atcgattttg ttctcgatta aaatcttcat tccacttgcg gcaattactc
     1201 caaataagat aaaactgatt cctgagatga ctggtccagg gatacttaaa atcaaagcgc
     1261 ttaattttcc tacgaatcct aaaatgactg caaatactgc agctccaccg atcacaaaca
     1321 cgctatggac acgtgtgata gccagaacac caatgttttc accgtaactt gttacaggag
     1381 gacctccgac aaaggctgcc acgatttgtg ctaatccatc acctgtcaac gtcttatgaa
     1441 gacccggttc ttcaaagaaa ttacgtttag ttagtttatt caataccata agatggccga
     1501 tatgctctgt catcgtcaca aaagcgatgg gtgccattgt tgtgattgct ccaagatata
     1561 gctttggttc atattgtaca aagggaatct caaagttagg aacagcaaac caggcagcgt
     1621 ctacgattgg cttagtatcc acgattccaa acagcaaggc tacgatgtat ccgctaataa
     1681 tacctagtaa aatcggaatc aatccgagaa aacctcttag ccacatgttg aagaaaattg
     1741 ttaatcctaa tgtgatcagc gctacagcaa tatacttgaa atcatacgtg ccctgattat
     1801 acatagcatt tgttgctgca tttgccgcaa gtcccaaccc gataaccatg atgactggac
     1861 cgacgacgat tggaggcaag attttatcca gccatgctga accgatcttt ttgatgatca
     1921 gcgcaacaat caaatagact aatccagttg tgactgctcc ttgtgcaatc gctggataac
     1981 catctgtttt catcaaaagc tgcatcgctg caatgaaagc gaagctgctt cctaagtacg
     2041 caggtatctt tcctttagta gtaaataagt acaccaatgt acctagtcct gaactgacta
     2101 gcgcaatacc tggatcgata cctactaaga tggggactaa cacggttgct ccgaacatcg
     2161 tgaacaagtg ttgtaaactt aatcctaccc aatgtcctgg ggttgggcga tcgtggatat
     2221 ctaacaccac gtcatcatta tgaaatcctt ttttctccga catgtttctc tctcctctaa
     2281 tcttcctctt tcaaaatcat gatgcgatct tgtccatcaa gctcttgcat ctctactaaa
     2341 atctcttccg cccgagatgt tggaatgttc ttcccaacat aatctgcacg gattggcaat
     2401 tctcgatgcc cacgatcgac caggactgct aatgaaattt ttcttggtct gccaaaatcc
     2461 attactgcgt ccattgctgc tcgaatcgtt cgtcctgtat acaaaacatc atcaatcaaa
     2521 ataacttctt ttccttctaa ggaaactggg atgtcagaag aatgaagttc cggttcttct
     2581 ggattttctt ttttgtcatc tcggtataaa gtgatatcca gttctcctac aggaatatcg
     2641 atatcttcta gctgcttcag gcgttcggca attcttgatg caatgtagat tcctcgtgtt
     2701 ttgataccta ccaatacgat atcttggata ctatggtttc tctcgataat ctcataagta
     2761 attcgagtca atgctcgctt catggttacc tgatctacta cttcttttgc ttgcattttc
     2821 attcccccta cttttttgca taaaaaaact cctgccctaa gaggacagga ggaatgttta
     2881 gactgagcgt atactgatac actgatagct atactatgtc aatgagcaat ctacttatgg
     2941 cgcaccatac gtatccttgc tcccaccctt cttagcctca cgggactaaa cttaaaggaa
     3001 ttctattaag ttttatgctt tcgttgttaa ttactatacc gttatctaaa ttaaaatgca
     3061 atgttttttc ttaatttttc taaagttttt tcaaaaactt ctggaagagg tgcttcaaag
     3121 atcatctttt cgtttgtagt cgggtgcgta aaacctaaca tttgcgcatg gagaaactga
     3181 ccattgcctt tcaaagtttt cttcggtccg tatactggat ctccagctaa cggataaccg
     3241 atatacttca tatgcacacg gatctggtgt gttcttccgg tttctagttt taattcaacc
     3301 agagtaaatc cttcgaaacg ttccaataca gtaaaatgtg tgacagccga cttcccatct
     3361 tctcttatcg cctgcatttt ccggttttcc ttcgaacggc cgattggcgc attgatggtt
     3421 cctttttcgt gaggaatctc tccatggact aaagcaacat atttgcgcaa agaggtctta
     3481 tcttttaatt gctgagctaa tgattcgtgt gcctggtcat ttttggcaac cattagcagt
     3541 ccggaagtat ctttgtcgat tcggtgaaca atacctggac gaataacgcc gttgatcgta
     3601 gaaagatcct tgatatggta catcagcgca ttgaccattg tgccatgcgt atgacctgct
     3661 gaaggatgaa cgaccattcc ttgaggtttg tttatcaccg ctacatcttc atcttcgtaa
     3721 acgatcgtca acgggatatt ttctgggacc acatctaatg tttctggttc ggggatcaag
     3781 acagtaatct cgtctccttg ttttactttg taatttgctt tgactggctg tccattgaca
     3841 gaaaccgctc catttttcag ccacagctga atttgcgaac gactgtaatc ggtgaataaa
     3901 ttagtcaata ctttatcgat cctaccagat tcatggtgaa tcgtcgtttt aagttctgtc
     3961 atttttttct ttgatccttt tcatctaaaa taatataaat taacatacaa atcactccac
     4021 atacaagtgt cacatctgct acgttaaaaa tcggaaagct cataaaatct gtctggaaca
     4081 tatctactac atagccaaga cgaatacggt cgataaaatt gccaatcgca ccagctagaa
     4141 tcaaactcaa tccaatcatg aaccagcgat tacctttttc acgattttta atcatcaatg
     4201 tgagaatcac aacgactgca atgagtgtca ctatagtaaa gaaccacatc ttcccttcta
     4261 gcatactcca tgcggctcca gtgtttcgaa tatgattcag tgacaaaata cctggtataa
     4321 gatttttcgt ctctccaagc gctagattat cagtgatcca ccatttgacc aactgatcca
     4381 ctcctactag caaagcgctg aatatccaat aaataattaa caaaaaatca atccttttct
     4441 atttgtttat aaatatcacg aggtcgtacg atcccgagca gattaccatc gggattccca
     4501 tctttagtga taagtacggc ttccaaagtc ccttgctcac gaaacatcgc ttcaacctcg
     4561 taaatatgtg ttttagctgg aacaaaatga taatttgtgt actttccgtt ttggatgatc
     4621 aaatccaacg ctcgtttatt tgttaaatca accggacctt tttggctttc ttttgctagc
     4681 caaaacccga tattacgtaa agtaatcaat gctacaaatt ttcctttatt gtataacgga
     4741 aattgtgaat accttttttc tgctactatc tttaacagtt caagtaacgg aagatcttgt
     4801 tcaaaacctg ttacacgttt tgcaaatcga ggcagcacgg tttcaggctg aatcagttct
     4861 tgttcgatca gctggattcg cttgactgtc caatcatttg gctctgcaat gacaaaatcg
     4921 actgcgatcc gatcatggac gatcgcattc cttaactgag caagctgtaa aagatcatct
     4981 tcgtattttc tgatcattaa ttgttttctt tgagctaggc gtctgacaag ttcggtaaat
     5041 cccatatttc gtgcatttcc catctcgtct ctcatccatt tttcgattcg attgaaactg
     5101 attaaaaaaa gatcagagtt tgccataatt ttcctccttg atcaaatatg cccggttttt
     5161 tatatagaaa aagaacgcaa tcaacacaat aactgcaaaa aaactgaaaa ataaattttg
     5221 taggaaaacg gcccccaacc cagttgctag aaataaaaac ggatagattt gaagaatcaa
     5281 gtaattcatt gtgatcacat aagcaggctt tgcttctttc actgtataaa cggggctttt
     5341 tagccaataa aaggtgacct gcatcgtaaa gggcacttcc agatcaagcg ttatcttttg
     5401 ttcatgactg agaacactgc gtttttcatt gttgattctt agctgaatcg agctacccat
     5461 accgtaaaaa ccggtttttc ttataaatgt cgttttcatc ataccctcct attatgcttt
     5521 agtatagctc aaaatacaat aaagaaaaag aatgatccta gtgtaaacaa aattaattcc
     5581 ctatcgtcta aaaaaagaag ctgtagtcaa aatacagctc cttcgatggt agattataat
     5641 caagcttaaa acaatcccaa cacttctccg tcatttgtca cgtccatatt caatgcagca
     5701 ggttttttag gcaaaccagg catcgtcata acatctccag tcaaggctac taaaaatcct
     5761 gcccctaatt ttgggatgat ttcgcggatc gtgatggtga aatcttccgg tgcacctagc
     5821 agtgaaggat catcagaaaa tgaatactgt gtttttgcca tacaaatcgg cagtttgtcc
     5881 catccattct tcgtaaactc ttctatttgt ttttgcgctt ttttgctgaa aacaacacca
     5941 tttcctccgt aaattttctt gacgattgtt tctgtctttt cttgtatcgt ttcttctagg
     6001 cggtataatg gcttgtaatt agcttctttt ctatcaatca atcgtactac agcttttgct
     6061 aaatcaacgc cgccttctgc tccatctgcc catacactcg ctctcttggc aagaatcccc
     6121 tgattttcac acaagtgctc caacagtgtg agttcattgt ctgtatctgt tacgaattca
     6181 ttgattgcga cgatcacagg tagctgatat tgttccatat tacgtatatg gcgctttaaa
     6241 tttgcaaaac ctactttcaa agcatcaaga ttctcatttt taagttcatc ttttttcatt
     6301 ccgccatgca ttttcaatgc acggacagtg gcgacaatca ccacagcatc cggcgctttt
     6361 ttcaagttag gtactttgat atctaaaaat ttctctccgc caagatctgc accaaatcct
     6421 gcctctgtga caacgtaatc tgctaatctc aatgctgtct tggtagctaa aatactattg
     6481 cagccatgag cgatattggc aaacggtccc ccgtggacaa aagctggtgt tccgtaaatt
     6541 gtttgtacaa gattcggctt gattgcatct ttcagcagta atgccagagc gccttctgct
     6601 ttcaagtctc cagcagtcac aggctgacgg tcaaatgtat agccgacaac gatccttgca
     6661 agacgagcct ttaaatcttc aaggtctgcc gcaagacaca agatagccat gatttcgctg
     6721 gcaactgtga tatcaaaccc atcttctctt ggaacacctt ggattggccc acccaagcca
     6781 acaattactt tacgcagttc acgatcattg agatcgacta cccgtttcca aatcactcgg
     6841 cgggcatcga tgttcaattc atttccttga tgaatatgat tatctaaaag agcagataat
     6901 gcattattag ctgttgtgat agcatgcatg tcaccagtaa aatgcaagtt gatatcttcc
     6961 ataggcaata cctgtgcata tcctccgcct gcagcaccac ctttgattcc catcacagga
     7021 ccaagtgagg gttctcgcaa tgcaataaca gattttttat tgattttatt gagcgcgtct
     7081 cctaacccta cagtgatcgt tgactttcct tcgccagctg gtgttggatt gatggaagta
     7141 actaagatca aatgcccctc agcgttatcc tttgatcgat tgattccaga aaaattgatt
     7201 ttcgccttat atttcccata cagttccaaa tcgtcttcct taagatctaa tttactagcc
     7261 acttcaacaa tcggttctag ctctgtttct tgtgaaattt gcagatcatt cttcatttga
     7321 ttaccccttt tcacgaactt tattcaacaa aatatcttct ttgttaagat atgccaatta
     7381 tacctttttt tattcagaaa aaaaacataa aattacaggt ttttaattta tttgacgtac
     7441 ttataaatac tctttataat gaaggctatg atcagacttt agaaaggtcg tgagtgcttt
     7501 gaccacagga attgtaaaat ggtttgacaa caaaaaagga tacggcttta tcagttatga
     7561 tgacacagaa gaaatttttg tacattttac tgcgattgaa gaagagggat tcaaaacttt
     7621 ggaagaaaat caagtggtcg aatttgagat catcgaaggg aatcgaggaa cacaagctgc
     7681 ccatgtcaag aaaggcaacg ttcagactac cgatactagt atgcatgaat agataaacaa
     7741 atagagtgag acgctaaacg ggatgaaccg tacgtctcac tcttttcttt tcctgtaaaa
     7801 attcgttttt ttaggttctg atttttaaaa ttagcttttt ctttttttcg tataaggata
     7861 aggaattgat tctgatttgg gtccgttttt ttcaaaatga tcaaaaagga ctacttgatc
     7921 tttttttcgc atcatgaaaa cagatggggc tttctcatct tgcaacatca tttgcacccc
     7981 agtattagtt ggcgtcaaag atcgaatctg tccgacagat atttctcggt ctttccaaaa
     8041 agcagcataa cgtataatca cagagtttga ttttaaaata aaagaacgcc gcaaacctag
     8101 aaatagaaaa acaagaaaaa tacctaaaac aaaattgctt ttccaataag gacctgtgtt
     8161 ttctaaagaa agaatcagac taaaaaacag aatgatcaag gtcaatgacc aatagatgat
     8221 cgtatgtgcc agttcaggct gccatcgaat attttttttc attctctaac ctctcaccga
     8281 ttcagtaatg atataatctt accataacat tagtttgaac aaaaaggaga atctcttttt
     8341 atgttaaaag tatacattga tgcctctaca aaaggcaacc ctggtcctag tggaggtgga
     8401 atcttgattg tctatcaagg taaacaagaa cagctatcta tcccgctttc tatagggaca
     8461 aaccatcaag cagagttcga agtcttttta aaaactttag aatttctaaa gaaaaacgac
     8521 ttacagaatg aaacgatttt ctgtttttca gacagcaaaa cactagtttc tacggtcgac
     8581 aaaaacgcaa cgaagaacga gctcttcctt ccctaccttc aaagaatcca agaacttcta
     8641 tccgaatttt ctttattgat cctgcaatgg ttgcccgaaa acaaaaataa aggagcagat
     8701 aatcttgcac gtcaggctct ccataaacaa ttaaaagaaa aaaagactct ttaaattaaa
     8761 aactttaagg agtcttttta tagtttctca tttaatataa aagataattg tgatcaaacg
     8821 taatttccaa ttggtaatct ccgatttttt cttctatttg actacgtaag attctttcta
     8881 gttctgtatc aacaaactgg aatttctcag ggaccactac atcaaattgc agcgtttttc
     8941 cttgatgaat tactctaaaa tcatgaatat taagccctgt acctgtttca agaagaattt
     9001 gctttaactg ccgcaagata ttatagtatt tttcgttatc aacaggcatt ggatccaagt
     9061 gacagacaag ttccacatcc aaagactttt taaagtcttt ttctatcaga tcaataatct
     9121 tatgagccac attcaaattc attgattcat ctacttcgat gtggactgat gcaaagcgtt
     9181 tattgggtcc atagttatgc accaataaat catgatagcc aagtatatca tcgcaagcat
     9241 ttaaatgctc ttccatttct tcaatctctg ctggcgttgg gcgacttcct aatagttcgt
     9301 atacaaaatt tcgaagcatc gtcaatccac tataaaggat atataatgct aaagcaaaac
     9361 ctatatatcc atcaatacgc catccagtta cccattcgat tgctgctgaa agcaatacag
     9421 ccagtgtagt aaagacatca ttataactat ctgttgctgt agctctcaat gtttcagaat
     9481 caatggattg cgcaataacc tgatacattt tgccttgtgc aaatttcaaa aagatggaaa
     9541 tgattaggac aaaaaagacg atgggtgtta aagagacatt ttctggatgg atgatttttt
     9601 cagcagaaga ctctaaaaat tgaaatccta cataagtaat gatgatcgaa acaaataacc
     9661 cactgatata ttcgaagcgt tcgtgtccat aaggatgttc ctgatctgct ggctttgcag
     9721 caattttaaa tccgatcaaa gtcaatatgg atgaagcagt atctgataga ctgttcactg
     9781 catcagccat aatggagaca cttcctgaaa aaagcccgat cattagctta gagacaaaca
     9841 agatcagatt cgtaaccaat cctaagatac ccgctagtac tccttttttt gtccgctgtt
     9901 gcggtatttg tttctttttt tcttcttgtt tcttagccaa gttttttacc ccttctagtt
     9961 tgcttgttgc tcaggtaaaa agatggagag gacgattgtt ttcctctcct ctcttccttt
    10021 ttctatctat cgtgcgtcct attactatta aaagatggtc attattctgg tttcaacggt
    10081 gttgctgcaa ataacgcttt tgctagtaat ggtgttatga ttcccgcacc tattgcttct
    10141 ggtatcccat tgattgctgc aacccctgct aaggttttaa ataaaagagc agagtctaca
    10201 ccataggcat ctgccgttgc acctgtataa aataatccca tgaatcctaa cactaagact
    10261 gtattgacca atgaacccag tacccctgca aaggctgagc tgatcgttat tgatttattt
    10321 ttttgataaa tccagtggaa aaccaagcct gctactaagc caacaagtac tctgggaact
    10381 accgagataa tcggattcgt gaacactaat gtatcaaatg gcgttgttgg catggcatag
    10441 gcacgaacaa ttgtagcgat tccccaaaac aagccaatca ccatgccatc ttttgggcct
    10501 aatactactg cagcaataat tactgtgata tggataattg ttaaactaat gaatcctaat
    10561 ggaataaacc ccagccaagg aaccatcgct tgtacgatga tgattgctaa caagatcgca
    10621 cgtaagacta gtcgaaaggt cttatttcta ctattcattt tttcacccct ttttatttat
    10681 actaatcgta aaaatttctg tcactttcgt caactaaaga ccatccgaat ccgaccattt
    10741 gattagatgc gccatccaat tgaaaaaagt atgagggcaa gacttgtttg tcttcgcccc
    10801 cataatcatg tttcgttcaa tgtttgaact tttgtttttc tgtcaaacgt aaacgcccta
    10861 ttgttgcgca acccattctt tcgcagcttt aagtgcatct ggaataccag caggattttt
    10921 cccgccagct tgtgccatgt ctggacgtcc accaccgcca ccgcctactt tcggtgcgat
    10981 tgctttaatc aagtcgccag cttttagtcc agcttcattt gattctttcg tcattgccgc
    11041 tagcagactg acttttcctt cttgttcgtt tgctaaaaca agaatatctg aaatattttt
    11101 ttgtttccat tggtcagcta attgacgcag ctgattcata tctttcactt ttacttgtgc
    11161 tgcaatgatt gtttttccat tgatcgtttc tggatctttg aatacatcac cagcttgttg
    11221 attcgctaac ttgctagcta attgttcatt ttccttttgt agctctctta cttgctgttg
    11281 caattgttcc gcttttgaaa caacttcttt caattgaggt gatttaacaa ttgttgctac
    11341 ttgttttagt tgtttttctt cttcttcaag tagttcgtac gcttctttac ttgttacagc
    11401 ctcgattcgt cgcacgcctg caccaattcc tgattcagaa acgattttga agattccgat
    11461 gttttctgta tttgctacat gtgtgcctcc gcacagttcg attgaccagc cgccaatatt
    11521 tactactcga acgtcatgtc cgtatttttc accaaacaaa gccattgcac ccatgttttt
    11581 ggctgtatcg atatctgttt caattgtttc aactgggata gcttcccaga ttttttcgtt
    11641 gacgattctt tccatttcag ctaattcatc tgaagtgatt tgaccaaagt gggtaaagtc
    11701 gaatcgtaaa tgtccaggag cgactaaaga accagcttga tttgcatgct cgccaagtac
    11761 ttctttcaat gccttgtgca gtagatgggt tgctgtatgg tttttgatga tccgattgcg
    11821 catcgattga tcgatcaata gatgataggt ttgtccttca ctcattggtg cttttacttc
    11881 tacggtgtgc ataaattgac cattaggcgc tttttgaaca tctgtaacaa ctgctacgat
    11941 ttcgcctact tcattcatga tccatccttg atccgctact tgcccaccca tttctgcata
    12001 gaaaggtgtt tgatcaaaga tcatttgagc ttcaccttct gcgacttcat tcaaaagaga
    12061 ctcaccttta acgatgacca ataattgact atctgattct tgttctgtgt atccaatgaa
    12121 tttactttct actttgatat ctgtcaataa agcagattgt acccccattg atttttcagt
    12181 actgcgggca gagcgagcac gttcgcgttg tgcatccatt tctttttcaa aaccagcatg
    12241 atcaactttc agtccttcat cttctgccac ctcttccgtt aattctaccg ggaagccata
    12301 tgtgtcgtat agtttgaaga tgtcttttcc tgctagagtc gtcccgtttt cgttttttac
    12361 ttcttggatc acttgattta agatttccaa accttcattg attgtttcat tgaaacgttc
    12421 ttcttctgta cggataactt tttcaataaa ttctttttgt tgaagtactt caggataata
    12481 acttaccatg atttccccaa caacagggac taaacgatat aagaatgctt gttcaatacc
    12541 taattttttc ccatgcatga cagcacgacg aagcaaacgg cgtaagacat accctctccc
    12601 ttcattcgat ggcaatgcac cgtcgccaat agcaaatgaa agggcgcgaa tatgatctgc
    12661 gattactttg taagaaatat ctgttactgg gttttcacca tattttactt gtttgcttag
    12721 cttttctacg gcgtggataa taggcataaa caagtctgtc tcaaagttcg ttgacgcatc
    12781 ttgaacgatt gagaccatgc gttccaatcc catccccgta tcaatgtttt tatgaggaag
    12841 tggttcaaat gtgttatcag gcttatggtt gaattctgaa aatactaagt tccagatttc
    12901 taaataacgt tcattttctc ctcctggata gttttcagga tcgtcttctg ctaaatcgtt
    12961 ataagcttct ccacggtcat agaaaatttc cgtatccgga ccacatgggc ctgcaccgat
    13021 atcccagaag ttgtcttcta catcaataat gtgatctagt ggcaggccaa cttcttcatg
    13081 ccagatgcgt tttgcttctg tatcttttgg ataaactgtt acataaagtt tttctggatc
    13141 gaatgccatc cattttggat cagtcaaaaa ttcccatgcc cagtggatgg cttcattttt
    13201 gaaatagtca ccaatcgaaa aattacccag catctcaaac atcgtatggt gccgtgctgt
    13261 tttaccgaca ttttcgatat catttgttcg aatagatttt tgggcatttg tgattcttgg
    13321 attttctggc acaactgaac catcaaaata ttttttcaat gttgcaacac cagagttgat
    13381 ccacaataag gttggatcgt tcacggggat caaagacgca ctaggttcaa tcgtatgtcc
    13441 tttagattgg aagaaatcaa gaaacatttg tcgaacttgt gcactactta attgtttcat
    13501 gtcattacct gctttctata aattaaatac aaaaaaacac catcacagcc aaggacgaaa
    13561 actcgcggta ccaccttgat tgcaatgatg tgtaatcatt acctcttaaa ctcgataacg
    13621 ctgagctgcg tcggtatttc taccaaaata gaaaaaggga gcaatttgat tagtgactat
    13681 tcttttttca gccaagaaag aattttctgt gagtcttaaa aaacaaatca tatccttttc
    13741 gtacttaatt agtatacgca ttctattgat cactgtcaat atctcaattt ttattttcat
    13801 ttccttttgg tcatactcca cgatttttgg tacgataaga ataaaggaat caatacatct
    13861 ctgctattca tgacaaggag gaatatgatg aaaaaaatag ttggagcgga tgaatggata
    13921 cgcgcagcta gctgcttttt gagatatcaa gtttttgtat tagaacaagg gattcctgca
    13981 gaactagaat tcgacggaaa agatatcccg caacaaacct attatctatt tcttgatcaa
    14041 aaaagaccag tagctacttt gcgttatgaa aagaaaacac ctacttgctt caagccggaa
    14101 cgattttgcg tagcaaaaga ataccgagga aaagggttag gcggtcagtt gcttgaagct
    14161 gctgaaaaac gggcggtttc agaaggttgt cagactagtt atgtagtagc tgaaatgacg
    14221 gctgtagatt tttatgaaaa acaagggtat catacttgca cagaaccttt tattgaagat
    14281 gaagtacttt gtatcggaat gaaaaaaagt ctagcttaaa aacaagagat tgtgacacgc
    14341 cttttgtcac aacctcttgt tttttattta tgtgaatttt tcttattttt acgagcagta
    14401 cggctttgct gtctgcgttc gattttgcgt tcttttttat ttttttctgc aattgcccaa
    14461 tcgatttttt tcttataacc aggcttgatc tttttctttt tcttcttcac aagaccaatc
    14521 agcgtgggat ctaatacatc ttttgatttt tctcgtttgg cacgtctatt acgatcgtat
    14581 gttttgacga tttccccgtt tttgatttct tttggttcaa atgagacgcc caatttttct
    14641 atcgcatcaa tggcttgctc atcatttggc gaatataacg taatggccgt tccttttaag
    14701 ccattacgtc cagtacgtcc gacacgatgg ataaagaagt ctagatcttc tggaatttct
    14761 gcattaataa catgagagac accttcgata tcgatccctc tagcagctaa atcagtcgct
    14821 acaacatatt gatactccag attctgtact tgtcgcatca ctcgttttct ctctcttggg
    14881 gtgatgtctc catgaatctt tgctactttc aagccttggt ttttcaagta atcggcaatt
    14941 tcatccacat gctgttttgt attggcaaat acgattgcta aataaggatg accaattgtc
    15001 agcagttgat aaatcatttg attctcatct ttaccttttg ttgaaatcag ccaattttca
    15061 atgtcttcag aaataactgc ttttggtttg atttcttcaa tgattggatt ttccatgtat
    15121 tttcgtaaga atggacgaag tttttctgga atagtggcag aaaaaactaa aaactgcagc
    15181 ttttctggta atcgacttgc aatttggtct acttcattta aaaaacccat atccaatgtc
    15241 atatccgctt catcgacaac aaatgcaaat gcggtgtgaa tcttcagcgc ttgttcattc
    15301 atcatgtcta atattctacc aggcgtgcct actacaacct gtggctgttg gtgatgcaga
    15361 cgatttaatt gacgctgttt gtctgtaccg ccgacaaaat tcgagacacg gatctccggt
    15421 gtagaaaatt tagcgatttg tgtagctgct tcatagatct gtgcagctag ttccctactt
    15481 ggagctgtaa taacaacttg tacttcctct ttttctgcat tgattttttc aaacaaaggc
    15541 aacaaaaacg tatgtgtttt tcctgtacca gtttgagatt gcccaatgat attttttcct
    15601 tttgcaatta aaggaatcaa acgttcctgg acctctgtgg gctgtttgaa gccctttgcg
    15661 gttaacgctt cattgataaa cggtttgaag cggaatatat caaaattatt cattcgtgca
    15721 cctcttctct ttaaattatc acgactttgg cattataaca cagacaaagc gtttttgctc
    15781 agctaatttc gagaatcatc atcctttgtt tggccaatcg tgctaacagt atatgtgtga
    15841 ctagcttttt cataaaacag aatccgtttt tttctcaaaa atgatagcaa gatatttaaa
    15901 ataaaaatac cttgtagtaa caagacaccg agagaaatga atactgcact catctgcaac
    15961 accgtattcg ttgtcgaatt catgatttgc tgaagcaact gccccaacca gcttaaacca
    16021 taaaaaagaa agtacagata cccgtagcgg atcatcaatg cttttaaaga aattcgttcg
    16081 cggtcttctt ccaccaaacg gatacgcaca atttttttgc caagtgtcca tccattggtt
    16141 ataaacggta caatcataaa gtatacccct acttctaata aaagccacca gatatgagaa
    16201 gtaactgccc ctgaatcgaa cgcaatttta aagaaaatcg ccgctaccaa attaataaga
    16261 gataaaaatg tccagtcgat caaataagcg accaagcgtc gagtcaatga gacagtcttt
    16321 cctttttcat aagaaagttc atccattcgt cttcttgtag gaagcataaa tgtaaataac
    16381 ggcgtaacga caaaaccaat gattccaccc aatgtatttg tcactaaatc attcacatca
    16441 aataagcggt atggtcttgg gtagataaaa taaagtccac ttagctgcgt caattcaaaa
    16501 aatagagaaa ggcagaaact agcaatcatc gttttcataa aagaaagccg gaaataatat
    16561 cttaaataaa tgccaaacgg tatgagtaat aaaacattaa aagctggttc caaaaataca
    16621 ctctgcttca ttgccggcag gtaggtacta ggttcagaca agaccaatac cgtgttgtct
    16681 ctgaaatgtt gccatgaagc aaataaatgc agctccatct ttggccctgt catttgggca
    16741 accgtctcct ttgccggaag tggtaagatc accaaaaaat acgcacacaa taaataaaaa
    16801 acgaaagaat acaaaataac tgcccttgtt actagaaatg ttccatactt tcgatattca
    16861 taaataaaaa aaacagatga gatcgctaag gctaaaaatg gaaaaacaat cagcgcaaaa
    16921 cgaatcggtt cgatataact tgccatatga ctcctccttg attctttgta tctctcttat
    16981 cttagcagtc ctttgctgtt tcaagcaagt aacgaggcta ttatttctca tttctttcaa
    17041 agtaaagtaa gataaacaca aagggggtgt cgagatgctg aatatgtact ttgtttttgg
    17101 cgtacctatt tttttactgt tcctttatgc tacgatcgct tatgtaagaa aaagaactac
    17161 aattcattat ttaggattta ttctcctgat tatttcgggt ttcatgctag tcttcaatct
    17221 tcagacttgg cagcaagcac ttcttgaaat ggataaaatg actccacatg ctttgtctaa
    17281 agtgcttggc taccctgtct atctgatttg gcttcccatt ttcatttctg gttgcttggt
    17341 tttattaaat atttatcgcg gcgtacgccg aatagttcag ttacgcaaat caaagtaaaa
    17401 gacagaaatc ggttgagccc gatttctgtc ttttactttg ctatttcatc gtagacaaaa
    17461 cgacatttac gtgatcaaaa ttaacgagta cttttgacat ttcttccacg tactcctcat
    17521 ttaaataaaa tattttgttt ggcagagaag tgcagttcta ataaaattcg aatgttttag
    17581 ctatctacgt tttaaataga gataaatcgg gataccagca agtgtcaata ctatccccat
    17641 cgaagctaaa aaggtctgag tgataagcgt gcttgatacg ataaaagtcc ctccaatgat
    17701 tgctactagt ggaataaacg gatacattgg aactttgtat ggtcgaaaca aatcaggttc
    17761 ttttttacga agaagaatga caccaacaaa gaccatcgta taaaaaatcc aaatgacaaa
    17821 gatcagcata tccgttagtg tatcaaaacc accgatcatc atcatgccaa tagcgatgac
    17881 tagctctaag atacctgcgg ctacaggaac tttagtttta tcatgaagtt tagcaaagag
    17941 cttgctaaaa ggcaggttgt tttcttttgc cataacataa gggagacgca ttccagtaag
    18001 ggtatagcca ttgatggttc cataaacaga aatcaagata ccaactgtga ccagtcttcc
    18061 accgaagccg ccaaaaatca tttttgcaac gtcacttgcc gcattgctgt ttcctgcgac
    18121 tccgtcgata gatgcggttc ttaagaacac cgcatttact aataaataaa cgatcatgat
    18181 tccgatgatt cctaaagaaa ttgcttttgg caaatctttc gccggctttt tcaattctcc
    18241 cgaaatattt cctacgtgta tccaaccgtc gtatgcgaac atcgttgcta gcaagcccgc
    18301 tcccaaggct gagaaaaatg aaagattttc tcctgcttgg atcggaaaca gttggaagtc
    18361 tactccttct tgtcggaaca aaccgaaaat gacgatcaca aacaaaggaa taagcttgca
    18421 gacaagcgta atcgactgaa aagcccctcc agctttagaa cctaaaaaat tgatcaacag
    18481 gatcgataca gcagctgtaa cagctacggg aacaatcatt gactgggaaa gaccaaatag
    18541 attgacgaac tgtgtaccga aaatgatcga caaggctgct acatttgctg gaaaataaat
    18601 cacgacttgc gcccagccca ataaaaaagc tgctgtattt ccgtaaatcc gttcgatata
    18661 tttaatcatc cctcctgttt ctggaatagc agctgccagt tcagctcctg ttagtcctgc
    18721 acagacagaa atcataccac cgagaaacca agaaaacata tgcaaactgg cggatcctgt
    18781 aacttctgct acgcttgcgg ctttaaaaaa tacccctgca ccgatcactg tgcccataac
    18841 agtcgataaa gcagtaaaaa atcccatcgt acgttttaat tcattttcta tttttacttc
    18901 ttttactggc gtggcttgat attcttccat cccttgtccc ctttcatacc atagccaatc
    18961 ccaaaagtat aaaaaacttt ttggatgtgg ttcttgtttt ataccgtctc taccaatttt
    19021 tctttcagtt tttccaacat atcctttgtc atcacatcta agtcgtattt cggcgaaaag
    19081 ccccattcct cttgcgcaca agaaacatct agtgaatttg gccaagattc tgctattgac
    19141 tgacgtacag gatccacatc ataatccatt tcaaaatctg gtatgatttt ttgaatagat
    19201 gctttgatct cttccgggtc aaaagacatc gccgatatat tgaaggcatt tcgatgaacc
    19261 aatcgatcag gatctgcatt catgagtttt ataatggcat cgatcgcatc tggcatatac
    19321 atcatatcca ttgatgtacc ttgatcaatg aaactagtgt actttccttc tttgattgct
    19381 gaataataaa tatcgactgc gtagtctgtc gtaccgcctc ctggcaaggt tgcataagaa
    19441 atcaatccag ggaaacggac accacgagta tctacgccat atttcacata ataataatca
    19501 catagtagtt ctccagctac cttcgttacc ccatacatgg ttgtaggacg ctgaagagta
    19561 tcttgtgggg tatgatcttt tggagtattt ggaccaaacg cgccgattga acttggcgta
    19621 aaaaatttca gctggaattc tctagcgact tccaatgcat tgaccagccc agtcacgttc
    19681 aaattccagg ctaattgtgg ttttgcttct gcaacagctg acaaaagagc agccaaatga
    19741 atcaatgtgt ccacttgata ttgttctgct atgctgcgca ttttttcgta atccattaca
    19801 tctaggatct caaagatatc gtttttctca atgacttcag gcatgcgtat atctgtcgca
    19861 atgacatttt cactgcctag ttcttgacgt agccgtgtga tcaactctga accaatttgt
    19921 cctaaacatc ctgtcaccaa tacttttttc atgatgatcc tccctgatct tttttactac
    19981 tatcttcaga tgattaacaa tatatgcgtg aacatgttct ctaattttaa atagacgaaa
    20041 aaactaaatt tagttaaata atttccattt cttttcctat tttttgataa actgctactg
    20101 cttcatcaag catttccctc gtatgttccg cagtcggcat atttctgatc ctgcctgtcc
    20161 caagaggcac agttggataa acgattggtt tagcataaat cccatgttcg atcagcttct
    20221 tagagaaagt ctgagtcact ttttcgtctc ccaaaatgac tggagtaata ggtgtttcag
    20281 acataccgat gttatagcct acttttttca attcttcttt aaaataatta gcattttccc
    20341 aaactttttc gacaagttcc ggatgttctt gcatcaaagt aatcgaagcc aatgcagctg
    20401 cagctgcacc tggagttagc gaagtagaaa ataggaatgg ccgacttcta gctttcaacc
    20461 agtcgattag tgttttcgat ccagctacat aacccccaac aacacctata gctttcgata
    20521 acgtgcccat ttgcatatcg attttgtcgc ttaatccaaa atgcttgacg gttcctgcac
    20581 cttttccagt tacgcctgag ccgtgcgcat catcgacgta ggtgatcagt ccatattttt
    20641 caacaatcgg aataatttcc ggcaatcgtg caatgtctcc atccatggag aaaacaccat
    20701 ctgtgatata catgattttt ttatatttct tactttctat cgcttccttt gcttttttct
    20761 caaggtcttt catatcttga tgtttaattc ggatgatttt tgctccggat aagcggcaac
    20821 cgtcaataat agatgcatgg tttaattcat ccgataagat agcatcttct tttgtcatta
    20881 ctgcagagat agcgcccata ttgcagttga atccagattg aaaggcgatt gctgcttctg
    20941 tccctttgaa ttctgcgatt ttttcttcta attgctgatg gattttcagc gaaccattga
    21001 tcgttcggac tgctcctgct cctacaccat aagtttcggt tgcttcaata catgcttttt
    21061 tcaattcttc gcgattggca aatccaagat aattgttgga tgctagattg atcatctttt
    21121 ttccgtctac gatgatacaa gcaccatttt cactttctag tatgtcgatc gtattgtata
    21181 accccttttc tttcagttga tccaattctt tctctaaata cattgttagt tctttggaag
    21241 acattgtctc cacctccata ttcatctgtc ttgcagaaca taccaaacat atatcgtgtc
    21301 attcatctac aaagcaagta tgctatattt ttgataacgc ttacactgat tatgagaatt
    21361 atttaaccac attttttatt tacagtatct ttttactttc aaatgactta tatagtatga
    21421 acaattacct tttagataat gatctatttt actctacctg ggcagataaa tacaacacaa
    21481 ccattgatag aagccctttc gttaaaatca attgtattct gaatatttaa tttatttatt
    21541 gcatagacca ataaaaatac ataaaatttc catcttcgtt tatcagcaat ttttaatttt
    21601 actctctgaa tatttcttaa aagttttact tgttgaattc gaaaaaagga ctgtgacaaa
    21661 agtcttgtca cagtcctatt cttccgaa
//
LOCUS       DAYYEF010000046        21281 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000046 DAYYEF010000000
VERSION     DAYYEF010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.048"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            132..506
                     /locus_tag="ACHA1B_002004"
     CDS             132..506
                     /locus_tag="ACHA1B_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFM8702755.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="ACHA1B_002005"
     CDS             complement(620..1249)
                     /locus_tag="ACHA1B_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFM8702756.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="ACHA1B_002006"
     tRNA            complement(1383..1455)
                     /locus_tag="ACHA1B_002006"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
     gene            1669..1742
                     /locus_tag="ACHA1B_002007"
     tRNA            1669..1742
                     /locus_tag="ACHA1B_002007"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1703..1705,aa:Asn,seq:gtt)
     gene            complement(1880..2044)
                     /locus_tag="ACHA1B_002008"
     CDS             complement(1880..2044)
                     /locus_tag="ACHA1B_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702757.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2339..3667
                     /locus_tag="ACHA1B_002009"
     CDS             2339..3667
                     /locus_tag="ACHA1B_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HFM8702758.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3869..4702
                     /locus_tag="ACHA1B_002010"
     CDS             3869..4702
                     /locus_tag="ACHA1B_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HFM8702759.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4718..5455
                     /locus_tag="ACHA1B_002011"
     CDS             4718..5455
                     /locus_tag="ACHA1B_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA];
                     GO_process: GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase domain-containing protein"
                     /protein_id="HFM8702760.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5610..6578)
                     /locus_tag="ACHA1B_002012"
     CDS             complement(5610..6578)
                     /locus_tag="ACHA1B_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HFM8702761.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6810..7643
                     /locus_tag="ACHA1B_002013"
     CDS             6810..7643
                     /locus_tag="ACHA1B_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HFM8702762.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7677..8516
                     /locus_tag="ACHA1B_002014"
     CDS             7677..8516
                     /locus_tag="ACHA1B_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM8702763.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8542..9102
                     /locus_tag="ACHA1B_002015"
     CDS             8542..9102
                     /locus_tag="ACHA1B_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM8702764.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9301..11022
                     /locus_tag="ACHA1B_002016"
     CDS             9301..11022
                     /locus_tag="ACHA1B_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HFM8702765.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11187..12329
                     /locus_tag="ACHA1B_002017"
     CDS             11187..12329
                     /locus_tag="ACHA1B_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase family protein"
                     /protein_id="HFM8702766.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12345..13556
                     /gene="thiI"
                     /locus_tag="ACHA1B_002018"
     CDS             12345..13556
                     /gene="thiI"
                     /locus_tag="ACHA1B_002018"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140741 - tRNA-uracil-4 sulfurtransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA];
                     GO_process: GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uracil 4-sulfurtransferase ThiI"
                     /protein_id="HFM8702767.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14129..14776
                     /locus_tag="ACHA1B_002019"
     CDS             14129..14776
                     /locus_tag="ACHA1B_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0051775 - response to redox state [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HFM8702768.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14905..15121
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15169..17814
                     /locus_tag="ACHA1B_002020"
     CDS             15169..17814
                     /locus_tag="ACHA1B_002020"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0004832 - valine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006438 - valyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HFM8702769.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18124..19437
                     /locus_tag="ACHA1B_002021"
     CDS             18124..19437
                     /locus_tag="ACHA1B_002021"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004326 - tetrahydrofolylpolyglutamate
                     synthase activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008841 - dihydrofolate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006730 - one-carbon metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="folylpolyglutamate synthase/dihydrofolate
                     synthase family protein"
                     /protein_id="HFM8702770.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19427..20080
                     /locus_tag="ACHA1B_002022"
     CDS             19427..20080
                     /locus_tag="ACHA1B_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM8702771.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20135..20827
                     /gene="radC"
                     /locus_tag="ACHA1B_002023"
     CDS             20135..20827
                     /gene="radC"
                     /locus_tag="ACHA1B_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HFM8702772.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20977..21177
                     /locus_tag="ACHA1B_002024"
     CDS             20977..21177
                     /locus_tag="ACHA1B_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFM8702773.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         7184 a         3551 c         4445 g         6101 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tacttgattc cggcatagct
     1681 cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc ctactgccgg
     1741 agtaaataaa gcttatgcaa agaaaaagaa atccaatcac ttgggtttct ttttctttta
     1801 ttattatgat gaatcaagct ttctgttttt gtcacgtatg ttgtaatctt tacgaaagag
     1861 tagagttggc tactcataat caaccatact tcccatcatc gctaaatacg aaataaatca
     1921 gcattcctac accaatcaaa gcacaagctg caccaagaaa agggatgaca ttcccaaagt
     1981 tatctgtatt cataagtatg ccaccaccca caaacaaaaa gccgccagca atcaggtttt
     2041 tcattttatt catctccttt cttacgttat agtatttcct tctttcaatg agtattttga
     2101 aagctatctt attgtatgat gttcttctag gcctcttctt tattatacag gccattttcg
     2161 ttatctcata gaaatattcc tttttatctg aaaactattg tataccgtat gacatttttc
     2221 ttcatgaagt tgtaagtata ttctcattca aatgaaaatt tcatcataga agagattgta
     2281 tttctaaatt cttaagagta aaatacgaag tataacttgg atttggaagg atgattggat
     2341 gaaagctatt acgcctgata tgacaacaaa atttaacaaa cagtttcaag caaatatcaa
     2401 acagcaggca ttgcagcggg cagttgtgaa gaacggaatt actgcttctg ctgaaaatgt
     2461 ttcagcacat gtggagaata caccggtatt ttctatagat ttggctacgg ggaaagtggc
     2521 taatcaaatg caatcggggc gttgctggat gtttgctgca ctgaacacat tccgtcataa
     2581 gatgctgaat caattccatt taaaagagtt tgaattatca caaaattaca cttttttctg
     2641 ggataaatat gaaaaggcaa attatttcta tgaaaacatc attgcaacag gaaaagaggc
     2701 aatcgatagc cggaaagtag ctttcttact cgctactcct caacaagatg gcggccaatg
     2761 ggatatgatc gtttcattat tccaaaaata tggcgttgtg cctaaatcgg tgatgccgga
     2821 aagtgcgaat agttcaaatt ctcgagattt gaataactac ttgaacaaat tactgcgtaa
     2881 agatgcagta gtgttacgga aaatggttgc tcaaggagaa acattagacg ctattgaaga
     2941 aaagaaagaa gaaatgctag aaagcattta taacttctta gctatctcat taggaacacc
     3001 tccaaaagaa ttcgattttg agtaccgcga tgaagaaaag aactatcatc ttgaccgagg
     3061 actgacacca caaatttttt atgataaata catcggtgta aaattagatg attatgttag
     3121 cgtgatcaat gcaccaacaa aagacaaacc attcaatcgt tcttatacag tagagatgct
     3181 aggaaatgtc gttggcggga aagaagtcaa atatctgaat gttgatatgg aaactttcaa
     3241 aaaattagcg attgctcagc ttgaagaagg agaatctgtt tggtttggtt gtgatgtagg
     3301 tcaatcttct actagaacta gtggcatcat ggccttagat gcttattcaa tggatgatct
     3361 atttgatacg gattttacaa tgactaaagc tgaacgttta gattttggag aaagtctgat
     3421 gacccatgcg atggtattga ccggtgttga cttagtagac gggcaatcaa caaaatggaa
     3481 agtcgaaaat agctggggcg aaaaagttgg aaagaatggc ttctttgtta tgagtgatgc
     3541 ctggatggac gaatatacgt accaaatcgt tgtaagaaaa gatttattga cgaaagagca
     3601 attaaatgcg ttcaatgaag aaccaattgt tctatctccg tgggatccaa tgggtgcttt
     3661 agcatagacg agtatttcaa tgaagagtat gtagtaaaga taaaaagagc tggcttaagc
     3721 cagctctttt tatctttaaa gtccattccc tgttttttat ggtccctgtg ctataattct
     3781 aaataaagga taaggattgg aaataatcct tttatcatta aaaatatgat gacgaagtag
     3841 aataaaattg ggagtagggg ggaaagtcat ggatatccaa actgttttat ctgatctgaa
     3901 attaaatggt aaagtgattc cagttgttgg tggcgatgtt aatcagacct atcgtataaa
     3961 aaccgaacat cgtgcttatt ttttaaaaat ccatccgaat gtaaaaaaag gattttttga
     4021 agcagaagta gacggattaa aagaactgtc agcattcgta cgtgtaccgg atacgtatat
     4081 gctaggtgaa acaagtgaag gcgcttattt gttaatggaa tggatcgagc cgggaaaagg
     4141 ggatcaacga gatcttgctg cagctttagc taatctccat cagcaaacag cgccacaatt
     4201 tggttttcgt aaagataact atttgggtac acttgttcag aaaaattctt ttgaagaaga
     4261 ttggtggact tttttcttta aagatcggct tgaatcccag atttctttgg cagaagaaac
     4321 gaatcgatgg aatgtacagc gtcaagaaaa gtatctgcga tttaaagaac gtgtattgaa
     4381 atcggttgaa ccaaaaaaga tcactccacg cctcttgcac ggagacctgt ggagtggtaa
     4441 tgtgttcttt gaccagcaag ggcatccagt ttttgtcgac ccagctgttt cttatgggaa
     4501 tcgggaacaa gatattgcaa tgagccagtt attcggtggt ttccgaccgg aatttttaga
     4561 tgcttatcaa actatatttc cattagaaaa gggatggaaa gaccgactgc cgatttacca
     4621 gttatattat cttttggcac atttgaatat gtttggagaa agttacggtt cccaagtaga
     4681 tcaattacta gaaaattttt aagaggaggg cgtgtttttg gcaaaaaaat ataccaaaaa
     4741 gcatgaagtt tcatattatg agtgtgacat caaccaaacg atgacatttc cttcgatgtt
     4801 aggagtagtt atcaaaacgt ctgaagatca aagcgaccag ttgggaagag gcagtgaatt
     4861 cgtcaatagc tttggactta cttgggtcat cacgaattat tccatggaga ttaatcgtct
     4921 ccctagagtc ggtgaagtaa tctcagtaac gactcaagcc atggagtaca ataagttttt
     4981 ctgttatcgg aacttctgga tccatgatga agatgggaaa gaattagtca aaatagaatc
     5041 tgttttcgta ttgatggatt ttgtgaatcg aaaaatgagc agtgttaatg aagagatcat
     5101 tgctcctttt gagagtgaga agatcaagaa aatcaagcgt caggaaaaaa ttgaaaagat
     5161 tgattcgggc ttcatgttgc catatcgtgt tcgtttttat gatatcgata gtaatcagca
     5221 tgttaataat gcgatgtatt ttaattggat cattgacgta ttaggatatg actttttgac
     5281 tacgcatgtt ccagaaaaag taattattcg atttgataaa gaagtagagt acgggaatga
     5341 gatcgaaagc cattttgaac aaatccctat cgaaaatggt gtcaaaacaa aacatgaaat
     5401 ccgaatgcaa gaacagctgt attgtgaagc aaatattata tggaaaaata aataaaaaag
     5461 aggttgtgac agaagggggc aacttcaaga aataagaaga aatttacgaa aattgtttct
     5521 caaatttttg taaattttcg acttagtttt cgaagaagct atttttgtca cagcctctct
     5581 ttttaagttt agctattaga taatgatgtt tagttttgga taaacgaaat caattcttca
     5641 cccgacaaac catagtttac agcaatcaat agttttaaac gtgctttttg actattaata
     5701 ctgttacaga aaataatccc cattttttct agttcttttc ccccgccttc ataatcataa
     5761 acaggctctg cgattccatt gaaacaacga gaaacaagta ctacagggat tttttggaca
     5821 agaagctttt ccaaagcagc taaggcttgt ggagggagat tccccgcacc taaagcttcg
     5881 attaccaaac cgtctacttt cgtatgggcg atggcttcca ataagtcccc ttgcatccca
     5941 gcatatgctt taacgatcgg gatagtccca tctacagcgg aaatgtccag tcgctttgtt
     6001 tctaaaagtt cctgcaagaa taaaattcga ttcttagtta ctaagccgat gggacccaat
     6061 gtaggtgttc ggaaagtagc aacatttgtg gtatgggtct ttgtcacgta gcgtgcagaa
     6121 tggatctcat cgttcatgac caccaaaacc cccttatcta gcgcttcttc acaacttgcg
     6181 acacgaatcg cactttcaaa attataaagg ccgtcacttc caagttcatt acttgaacgc
     6241 attgccccag tcaaaacaat tggtaatttg ttgccaatcg ttgtatcaag aaaaaaagca
     6301 gtttcttcta atgtatctgt accgtgtgtg atcaccactc cggatatacc tgatgcataa
     6361 gcggacaaga tacgttcttt taataccaac atgtgagaag gcatgatgtg tggtgaggga
     6421 agattgaaga tatcttcaac taataattct acatgcttgg ggattgtgat ttctgcatct
     6481 aataatgggt ttgccacatc aggactaaca ccgcccgtga gcatgttttc tttcatggcg
     6541 atcgttccgc cggtgtgtag tacaagtatt tttttcattt tacagacttc cttacgaata
     6601 attttgcata gccgttaaat cttattgtat actatataaa agagttttgc tatcagtgaa
     6661 gaataacgaa tagcctaact tatcataaaa aagctgacct tattaaaatg gaaaagactc
     6721 aaccttgacc tcctaataca atggagtatc tggttgagtt tcttttacaa gaaagcagcc
     6781 aaggaaatca atcacgaagg tggccggaaa tgatcagaat cggattaaca tcgtttaaag
     6841 aacatgacaa attaactggt aaaaagaata acactcttta tgaatatgca gggtttctac
     6901 ccttagtgga attagatact gcctattatg gaattccccg aaagtcctca gttgagaatt
     6961 ggataagtga agtacctgaa tcatttcgct ttgtagtcaa agtctatcaa ggaatcagcg
     7021 gtcaaggaga ctggaagcct tattatcaga ccgaagaaga gatgattgcg cattttttag
     7081 atgttatgtc gccaatggta gatgctggaa agatgttttg ctttttagtc caattcccct
     7141 catcattcaa atgtacgaaa gaaaatgtcc agtacttgcg caaacttaga aagtggtttg
     7201 agggttatcc tgtttctata gaattgcggg attattcttg gtacagcgat gaatttcttg
     7261 aacgtacaag aaactttatg tctagagccg ctttttcttt agccatcatc gatgagccac
     7321 agttgctgaa tacaacgatt ccttttgatc catttgtcac caatccgaac tttgctcttt
     7381 ttcgattcca tggtaggaat gcgcaaggat ggcaagcaaa tgataaagag tggcgtaaaa
     7441 aaagaacgtt atatcgttat tcagaaaaag aactgcaaga actagcacat gaagtcaaag
     7501 tagttgattc taagacaaaa gaggtaggtg tgatttttaa taataattct ggtggtgatg
     7561 cggctgaaaa tgcattagca ctgcaaaaaa tattaaatat caagccagat ggactcaatc
     7621 caacccaaat ggatctgttt taagggctta ttttattcaa gaaaggggcg aagtctatga
     7681 tcaaagctat tttttttgat attgacggaa cattggtcac caatcgttca aaagcgttgg
     7741 aatcaacaaa acaagcaatt gaatatgctc ggaaaaacgg cattttatgc ggtgtagcaa
     7801 cggggcgcag cccagtaaag atcaaagaaa tcattgatga attggaatta gatatgtatg
     7861 tcgtgtataa tggtcaactg gtttttactg cagatcgcac gattatcgac cacccttttg
     7921 aacaaaaagt attggaacat attgttgaat ttgcagatga gaaccatcga caaatcgttt
     7981 ttggtgcgag aaatcggtta gatggatcaa cgacgatgct attaggacaa tcgattttta
     8041 tcaagcgact agtcagcttt ttaccgcgta aattcccggt acgtctgatg aaaaaaatcc
     8101 tccaggtttt tagccctcac cgacaaaagg atcgttatga aacgttagag atattaaaag
     8161 aaccaattta tcaatgtata ttgctcagtc cggagtcaga acagaaaaag ttagaacatc
     8221 gctttcccga gtgtacgttt cagcgttcaa atacgtatac tgtagatatc atcccaaaag
     8281 gtggttcaaa attactaggc atccaagctt tcgcaaatgc tgtcgaaatt gaaatggaag
     8341 aaattatggc attcggcgat cattacaatg atatcgagat gctgaaaggt gtaggaattg
     8401 gagtggccat ggggaatgct cagatcgaag taaaacatgc tgcagacttt gtgactcaat
     8461 caaatgaaga agatgggata tacgaaggac tgaaacactt cggtctgatt tattagtcaa
     8521 tgaaagaagg aaaaaatcag tatggaagca gagacacctt ttcaaaaagt agaaacattc
     8581 cacaaaactt ttgatccaag aagaccagag atacccacgg cttttacaga aaatgaagct
     8641 catacacgtg ctgcgttcaa aatagaagaa cttgttgaat ttgttgcagc tacttcacct
     8701 aataaagaac aactgcatga agctgttatg ctgctgcacg aagcattaga taaagcagaa
     8761 gaaaaaatac ttggtaaaac acagtgggga agtgatccgc tggttgaaca agtagatgca
     8821 ctgacagata tcctttactt tacttatggt tctttttcat tactaggaat agtgcctgat
     8881 cgaatattcg aaatcgtcca tcaggcaaat atggggaaat tatttccaga tggaaaacct
     8941 cattatgacc ctgtaacaaa taaagtgttg aaacctgaaa actggcagat ggaatatgct
     9001 ccagaaccta aaatcgcggc agaaatccaa cgtcagattc aagaagcgat tgctaagaag
     9061 aaatccgctg atataggcat gtgcacaaat gaaaaagagt gatcagagtt tcactatttt
     9121 tgttatcttt atacgatgga aaaacaaaag attttcgttt aagttagtga atgcatgaaa
     9181 atagtatgct ataatctaga atagatgtct tttgcacgag agacgtatta tttggattta
     9241 tgccaagcag aacgccatct gttgcataaa agatgcatac tgaaaacgga ggaaccataa
     9301 atgggaaata atgttatcat cggaatcgtc attgcaatca ttatagtcgc cattgtcgtc
     9361 tttttggtta gttacttgat gaagaaaaaa aaccaagatc gattggatgc cttagaaaaa
     9421 cgcaaggaag aattatttga cttgccagtg attgaagaag tcgatgatgt taaaaaaatg
     9481 catctggttg ggcaaagcca aaataccttt cgtgaatgga gtcaaaaatg gaatgacata
     9541 tctacttcct cgttcgctga actagaaagt caaattttcg aagtggaaaa cctcaatgaa
     9601 agttttcggt tcttaaaagg aaaaaaagca gttgttgaag cagaagctac aatggaccaa
     9661 atggagaaac aagtgacgga aatccgtgaa ggtctaaagg aattgcggga aacggaagaa
     9721 cgcaactcac tagctgttca gcaggcactt gacgtctatg aagaactgaa agaaaaagtc
     9781 agagaagacg agcatgaata cggaccagct ctttttgaat tgcaaaaaca gatcaaagtg
     9841 atcgaaaaag aatttacgca gtttgtgact ttaaacactt ctggagaccc tgttgaagcc
     9901 cgcgaggttt tggataaagc agaaaaacat acgtatgaag tggaagctct gatgaaaaaa
     9961 attccaccgc tgtatgagga gctccatacc actttccctg aacaacttga agaaatcagt
    10021 gatacttacg agaaattgat ggaagaacaa tatgtattcc cagaagaaga tcttgctgaa
    10081 gatatcgcaa aagtaagtcg aagaattgaa aattcattag ccaatcttga aaaaacagaa
    10141 gttgaaacgg tcgaatttga aaaccgtgaa acagctgatt tgattgattc gttatatgat
    10201 atcttagaac gggaaatgga agctcagaga tatgtaaaaa ctaaccaatc aacgattgca
    10261 gagtatatca aacatacaac aaagaataac cgtcaattat tgattgagct ggatcacaca
    10321 tctcaaagct atacattgaa ccacaatgaa attggccgtg tacgaggttt ccaaaccgaa
    10381 gtggaagaaa tggaacgtca aaatgaacag atgattccac agatccgtca acacgaaatt
    10441 ccttattcag aagtgcgcac gttctataaa acagtcttca aagtcttaga agatatcgaa
    10501 aagcaacaag tagagatcga cgactcatta catgaattga gaaaaggcga aaaagaagcg
    10561 caagaaaaga tcgatacatt cgaattcaaa ttgcgcagtt tgaaacgttt tgtagaaaaa
    10621 caacgtttgc ctggcttgcc gaatgattac ctagaattct tttttgttgc tactgaccgt
    10681 attgaagaac taagtgttgt cttgaataaa attcgagtaa acatggaaga ggtcaatcgt
    10741 ttagttgctc tatgtgaaga agatctagaa ttattagata agaagacaca tgatttagta
    10801 gatgcagcag cattaacgga gcaaatgctc caatatgcaa atcgttatcg tcatacacac
    10861 gaagaagtga gagaagcaat tgataaaagc tactatttat tcaataaaga atatcactat
    10921 caagaagcat tagacgaaat cggtacagca ttagagcgag tagaacctgg tgctttcaaa
    10981 cgcatcgaag atttttattt taatcatcca gacttagtat aaagcaaaaa agttagtaaa
    11041 ccagcaagag caagacggat tattgtcttg ttcttgtctt tttttgtata tttgaaaatt
    11101 gaaacaagtg aaaatttcac ctgctcttga aagcaccttg gacaaccgtt ataatagaaa
    11161 agaatttcaa aaaagagggg tttcttatga tatattttga taacagtgca acaaccccaa
    11221 tctttccgca aagcttagat gcatatgtaa aaaccagtca gcggattatt gggaatccat
    11281 caagcttgca tgatttaggc aatcaagcta accggttgtt gcagcaagca agaaagcaga
    11341 tcgctgattt gatccatgta gaaccagaag aaatctattt tacttcaggc ggaacagaag
    11401 gagataactg ggtattaaaa ggaacgatga tcgaaaaaag agaatatggg aatcatatga
    11461 tcatttcagg agtcgaacat ccggccgtca gcgagacagc agaacaatta aaagaattag
    11521 gaatcgaagt aagtatcgcc ccagtggata aacgcggatt tgtacgtgtc gacgaattga
    11581 aagaattaat aagaaaagag acagtattag tctctgttat ggctgtgaat aatgaagtag
    11641 gatcgattca gcccatccag gaaatcagtg atcttttgga tgattttcct aaaattcatt
    11701 tccatgtaga tgctgttcag gcgattggaa aagtaccatt ctcgcaatgg ttgacagaaa
    11761 gagttgattt tgcaacattt tcagctcata aattccatgg cccacgggga actggtttca
    11821 tttattggaa aaagggtcgt cgtttagcac cattactgac aggtggaggg caagaaagaa
    11881 atcagcgaag tgggacagaa aatgttccag gtattgtggc tatggttaaa gctttacgtt
    11941 tatcattaga gataaaggaa caaaaacctg agcagacaca acgcttaaaa gtagctctaa
    12001 tcaatgcgtt gaagacgtat gagaaagtga cgattttttc agaaggaact gactatgcac
    12061 cgcatatttt atgttttgct ctaaaaggaa ttcgcggcga agttctcgtc catgccttag
    12121 aagaaaaaca aatatttgtt tctactacta gtgcctgctc ctcacgtaaa catatggcaa
    12181 gcagtacatt gcacgcaatg catgtaccaa atgatctggc tacatctgct gttcgaatca
    12241 gcttagatga aaacaattcg cttgcagaag tcgagcaatt tatgattatt ttcaagcagc
    12301 tttataagaa attttctgca atcaattaaa agaggagtgt tcttgtgaaa tacagtgaaa
    12361 ttatggtccg ttatggggaa ctttcgacaa aaggaaagaa tcgaaaaagc tttatcatgc
    12421 aactagcaca aaatgtcaga caagctttga aagactttcc agaaatcaaa atccatgctg
    12481 atcgggaccg gatgcatctt ttattgaatg gcgcagacgg gcagctagtt attccaaaac
    12541 tagcaaaaat atttgggatc caaaatttct ctccaagtat tcgtgtagaa aaagatgtcg
    12601 aagttttgaa acaagctgtt caagacatca tgaaagaaat ttatactggg aaagaaacat
    12661 ttaaaattat cgctaaaaga agcgatcacc aatttgaatt gacaagtaat gaattgaatc
    12721 aaacattagg taatgctgtt tttgatattt tcccgcatat ccaagttcaa atgcgtcaac
    12781 cagatattcc attacgtgta gagattcggc gtgatggcgc ttatctatcg tatgaaacga
    12841 tcaagggagc tggaggattg cccgtaggaa caagcggaaa aggaatgctt atgctttctg
    12901 gggggattga ttctcctgta gcagggtact ttgccatgaa gcggggagtg gaaattgaag
    12961 ctgttcattt tgctagtccg ccgtatacaa gtgaacaagc actgcaaaaa gcaaaagatc
    13021 taacagccaa actagcacct tatgtgggaa cgatccattt tatcgaagtg ccatttaccg
    13081 agattcaaga agaaatcaaa aagtcagtgc cacaaggata ttggatgaca attactcgtc
    13141 gaatgatgtt gcgtttgacc gatgaaattc gccgtattcg tcatggttta gtcattttga
    13201 atggtgaatc attaggtcaa gtggcttcac aaactttgca aagtatggtg gctatcaatg
    13261 aagtaacgaa tacgccaatc attcggcctg tagcgacaat ggataaactt gaaatcattg
    13321 aagtagcaga acagatcgat acatttaatc tttctatcca gccttttgaa gattgctgta
    13381 cgatttttgc tcctccacag ccaaaaacac gccctcaact ggaaaaggtc catcaatatg
    13441 aagagcgttt agcaatagat gaaatgatcc aacgagcact agctggcttg aagatggaag
    13501 agatacaagc agaatcgtct aatgaaaaaa ctgaagaatt ttcagaattg ctataagagg
    13561 ttatgaaaat agtgttttga ccagagtatt agagaaacaa aacgaaaaaa tagctccatg
    13621 tattttaccg tttttgaact aatgtcgaag attagctgat tgaataccat ttatcaagaa
    13681 gttatggaaa agccggttct tttttactaa ctgaaaaata aaattttatt tagagatcaa
    13741 gctacagttg ataaatgata taaaaaagag aatttcccat gaaatagcga ggttgtgaca
    13801 gaagtgggca gcttcaagaa ataagaagga atttacgaaa attgcttttc aaatttttgt
    13861 gaaatttcgg cttatttttc gaagaagtta cttctggaac accgtgtatc agaggttgcg
    13921 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt
    13981 acgtttggtt gagcttatta ccgcagatgc aagcttttga acaccgtttt atttgtctca
    14041 cacccttttc cttcctactt gtaaccttgc tcccgtgtta gaaacatgtt acactaaata
    14101 tgtgaaatta ttaacaagga gcgtcgttat gcgagaaaaa acagatacac tgccaaaagc
    14161 aactgcgaaa agattacctt tatatttacg ctacttgaag atgctggatg actcaggtat
    14221 aagtagaatc aaatcaaatg agttcagcga aatcacccaa attccttctg caacgatccg
    14281 cagagacttc tcgcaattag gcgagctagg cagaagcgga tatggctatg atgtcccttt
    14341 tcttatcgat gtattcaata atatccttaa tactaaagaa gaaaaacgaa tcgcattagt
    14401 aggatatgga aatcttggca aagcattgaa acacaacaat tttagaagaa atgaaaatct
    14461 aaatatcgtg tgcgtctttg ataatgatcc agcactgatc aatcgagtaa ttgatggaga
    14521 aatgatctat ccgattgatc gtttcgcgga gatagccaaa gcaaaaaatg tgacagtagc
    14581 aatctctacg gtaccaagta aatattcaca atctgctatt gatgaaattg tcaaaggaaa
    14641 tgtaaccgct atacttaatt ttgcgcctga cagagtaact gtcccagctt atgtcaatgt
    14701 tcaatacatt gatttgacaa ccgagttgca gacgcttatt tactttgatg agaattactc
    14761 agaagttttt tcttaggaaa atttgagtag gcttattgat cttgcgagaa ctcgtcgtaa
    14821 ttctttcaaa aattttttag tactaaatga agtggttttt tcacgaccac ttgttgacta
    14881 aaaaaaaaaa ccattgtaga atgaagcata acgctgaaca agaggagtaa ctggcacatt
    14941 cattcttaga gagagaacta tctgctgaaa ggttctcaat gacaaccagt gaaggtagct
    15001 tgggagtttc tgtcttgaat ggagtagaga tagacgagtc gtgatcgtta actcacttga
    15061 gaggcaataa tgattgatta ttgcaattta ggtggtaccg cgtaaatcat acgtcctaga
    15121 atacgaaagt attttaggac gttttttagt ttaaaggagg aaaacagcat gacggaagaa
    15181 aataacctat caacaaaata taatccgcaa gaagttgaag ctggacgtta tcagcattgg
    15241 ttagaacaag atttgtttaa accgagcgga gataaaaaag caaaacctta ttcaatcgta
    15301 atcccgcccc caaatgttac tggaaaactt catttagggc atgcttggga tacgaccttg
    15361 caagatatgc tgattcgtca aaagagaatg caaggatatg atactttatg gctgcctggt
    15421 atggaccatg caggaatcgc gacacaagca aaagtagaag cgaagcttag agagcaaggg
    15481 atttctcgtt atgatctagg tcgtgaaaag ttcatcgatc aagtgtggga atggaaagaa
    15541 gagtatgcga gccacatccg cgaacagtgg gctaaaatgg gcttatcttt agattacagt
    15601 agggaacgtt ttacattaga tgatggatta tctgaagcag tacgtaaagt ttttgttacc
    15661 ttatacgaaa aaggtttgat ttatcgtggt gaatatatca tcaactggga tcctcaagca
    15721 cgaacagctc tatctgatat cgaagttatt cataaagata tcgaaggcgc cttttatcat
    15781 atgagctatg aactagcaga tggatcaggc gtagtagaaa ttgcgacaac ccgtccagaa
    15841 acgatgttgg gagatacggc gattgctgtt catccagaag acgagcgtta tcaagcgctc
    15901 atcggcaaaa aagtgattct acctttagtc aataaacaaa tcccaatcat tgcagatgaa
    15961 tatgtagata tggaattcgg gacaggtgta gtaaaaatca ctccagcaca tgatccaaac
    16021 gactttgagg taggtaatcg tcatgatctt ccacgcgtaa atgttatgga tgatgatggt
    16081 acgatgaatg aactagcagg aaaatatgct ggaatggaac gttttgctgc tcgtaaagca
    16141 atcgtgcaag atctgaaaga aatcggtcga ttgattaaaa tcgatacgat gatccacagt
    16201 gtgggtcatt ccgagcggac aggtgtcgtt gttgaacctc ggctgtctac tcaatggttt
    16261 gtaaaaatgg cgccgttagc gaaaaaagcc attgataacc aagaaacaga tcaagcagtg
    16321 gaattcttcc ctccaagatt caatcaaacg tttttacgtt ggatggaaaa tgtccatgat
    16381 tgggtaatct cacgacaatt atggtgggga catcaaattc ctgcatggta tcacaaagaa
    16441 acaggtgaaa tgtatgtagg gatggaagca ccagcggata gtgaaaactg ggtacaagat
    16501 cctgatgttt tagacacttg gtttagttca gctttgtggc ctttctcaac aatgggctgg
    16561 ccagatacgg aaagcgaaga ttataagcga tacttcccta ctagcacttt agtaaccggt
    16621 tatgacatca ttttcttctg ggtaagcaga atgattttcc aaagcttgga atttactggc
    16681 gaacgtccat ttgagaatgt cttgattcat ggattgattc gtgacgaaca agggcggaag
    16741 atgagtaaat cattaggtaa tggaatcgat ccgatggaag taatcgaaaa gtatggagca
    16801 gatgctctcc gctggttctt atcgaatggt tctgcaccag gacaagatgt ccgcttcagc
    16861 tatgaaaaaa tggatgcttc ttggaacttt atcaacaaaa tctggaatgc ttcacgtttc
    16921 gttatcatga atatcgaagg aatgaccgta gaagagatcg atttatctgg agaaaaatca
    16981 gtggctgacc ggtggatcct tactcgtttg aatgaaacga tcgaacgagt aactgagcta
    17041 tttgatcgtt ttgaatttgg tgaagcaggt cgacaactgt ataactttat ctgggatgat
    17101 ttttgtgact ggtacatcga aatgagtaaa gaagtacttt atggagatga tgctgtttca
    17161 aaacaaacca cccgtagcat cttagtccat acacttgatc agatcctacg tttattgcat
    17221 ccaatcatgc cattcgttac agaagaaata tgggaacata ttcctcatca gggaaattct
    17281 ctagtagtgg cagaatatcc tgttgtacgt ccagagtttg atgatgaaac agcttctaaa
    17341 gggatggaag tattgaaaga attgattcga gccgttcgaa atattcgttc agaagtgaat
    17401 acaccattgt ctaaaccaat tacgttgcta attaaaacaa acgatgctaa aatcgatcaa
    17461 tttttagttg aaaatacaag ctatatcgaa cgcttctgta atcccgaaga gttgacgata
    17521 tcaagtgaga tcactgcgcc agatctagcg atgtcagctg ttctgacagg tgcagaaatc
    17581 ttcttgccgt tagcaggatt gatcaatatt gaagaagaaa tcaaacgatt agaaaaagaa
    17641 ctggaaaagt ggacaagcga agtaaaacgt gtccaaggaa aactttctaa tgaacgtttt
    17701 gtttctaacg cgccggaaga agtagtagag gcagagcgtg caaaagaaaa agattattta
    17761 gagaagcaaa cggctgtcaa agaacgaatc gaaagtttgc gtactattca ataagaatag
    17821 aaaaagagag tgtgaaatca gctagctatt actaaaagct agctgattga acatcgttac
    17881 aggaaagagt ttgagcctca ctcttagctt cgattcataa ggagatgtga cataaatttt
    17941 gtcgcatctc ttttttagtc tactcttatt atgtaggaga aggagggagg tggatcatgt
    18001 atcaagagtc aataaagtag ttgataaaat cgttcctctc tctgtttctt ttctctttgt
    18061 catactttta tttttcttat gtgttctatt tgttataata aaagagaaat gggggaattg
    18121 ttgatgacga ttgaagaagc aatagaatgg atccatagtc gattaccatt tggttcacgt
    18181 cctggccttg accgagtcga agctttatta gaagtggtag ggcatccaga gagaaaagta
    18241 aaaacgatcc atatcgctgg aacaaacgga aaaggttcta ctgtagctta tttgagaagc
    18301 ctattagaag aggctgggct gacagtaggt acatttactt caccttatat cgaaacgttc
    18361 aatgaacgga tcgcaatcaa tggcaaaagc attccagaca atgatttgat ccagcttgta
    18421 aaaaaatatc agccactgat caaacaactt gatcaatttg aagcagtagc tggtattact
    18481 gaattcgaga cattaacagc aatggcattt gattattttt tgatgaagaa agtggacgta
    18541 gcgattatcg aagttggctt aggcggctta ttggattcta ccaatgtagc tgtaccaatg
    18601 ctgacgggaa taacaacgat tggacttgat cataccgaaa tacttggaga tacaattgaa
    18661 gaaatcgctg cacaaaaagc tggaatcatc aaacaaggcg ttccagtagt aacaggaaat
    18721 attgccccag aagcttttac tgtcatccaa caaacagcta aagcaaaaaa tgcaccgctt
    18781 tatgtatacg gggaaaatta taaaataaac tatctgcatc ctgatgagat gtggggagaa
    18841 gtatttgaat tttttaatga aataggaaag atccctcaat taaccactcc gcttttaggg
    18901 caacatcaag ctgaaaatgc aggagtagcc atcgaattgt attttgttta ctgtcaattg
    18961 gaaaagctgc ctttccgaga aaaagatgtt ttgaagggat tgaagaaatc tcgatggcca
    19021 ggaagaatgg agcgtttgag taacgagcca ttagttgttt tagatggtgc ccataatacg
    19081 catgcaatga accggcttgt tgagaatttg aaaaaagaat tcaaaggata tcaaatcaac
    19141 attttgtttt ccgccttacg aactaaaaat gttagagaaa tgctagaacg attgcagcaa
    19201 gtaccaaatg tccatattta tttgacgacc tttgaacatc caaaagccat cgaattaagt
    19261 gaagtatcag atttagcaag tgagagagta tcaatcgttt cattgtggca attcggatta
    19321 gcagatatat tggaaaagat gacaaatgaa gacgtattag ttgtgaccgg ttcactttat
    19381 ttcatttcag aagttcgcca tttattaata caattaggag gagatcatga agtataatgc
    19441 agtgattttt gacatggatg gtttgctgtt cgacacagag ttagtgtatt acgaagccac
    19501 acaagtagta gcagacaaga tgggttttcc ttatgataaa gacctgtatt taaaattctt
    19561 aggtgtttca gatgaagaag tatgggcgaa ttatcatatg attttctcgg aatttggcaa
    19621 aacaagtgta caaagattca tagatgattc ataccaggaa acgcttgaac gtttttcgca
    19681 aggagcggta caaatgaagc ccggtgtgtt ggaactcctc tcttttttag aagaacatca
    19741 gattcccaaa gttgtcgctt ccagtaacca acgagcagtc attgaacttt tattgaagaa
    19801 gaacaatctg tttgaacgat ttgagacgat tgtttctgca gaaaatgttc aacgagcaaa
    19861 accagaccca gaaattttct tgttagctaa tcagaagcta ggtacagcga agaaagaaac
    19921 attgatttta gaagattcac aaaatggtat tttagcagct tctgcggctg agatcccggt
    19981 agtcatggta ccagatctgc ttccaccatc ccaagaattg atcaaaaaaa cagctggggt
    20041 tgtttcttct ttacatgaaa tccctgcatt gttaaaataa aaatccatct cttttcgtat
    20101 cttattttag ataagataga aaggagatgt ttttttggga aaacgattga tcaaagaagt
    20161 acctactagc tctttaccaa gggaacgtat ggaaatttat ggcgcggaag ctttatcgga
    20221 tcaggagctt ttggcaatct tactgcgtac cggtcaacac ccttatagtg tgatgtcgat
    20281 tgctggaaat ctgttaaaaa cgtttggagg actggcctct ttacgacagg ctactttgca
    20341 tgagttagaa gagattcgag ggataggacg cgtgaaagca atcgaaatca aagccttgat
    20401 cgaattaggt cgacgaattc agacggatca tgaaagagcg gctccaccgg ttcgtaccag
    20461 ctacgaattg gcccagcaat tgattctgga aatgaaagat cacaaacaag aacatttggt
    20521 ttgtatttat ttggacacga agaatcaagt gatcttaaaa aaaacagtgt tcatcggttc
    20581 gctgaatcag tcagtcgctc atcctagaga aattttccat tatgctgtac gttattgtgc
    20641 agcaaggatc gttttagcgc ataatcatcc ttctggtaat gttattccat cgcagcagga
    20701 tatgaatttt accaaaagga tacaaaagtg tggagaaatg atggggatca ctgtactgga
    20761 ccacttgatc atcggacgca aacgatattt tagtttgaga gaagaaggaa tgatggaaga
    20821 gaagtaagtt gctttcttgc aaaaaaaatg aagcaagtgt acaattatat tgtaattttg
    20881 tttgggaata gaagttgaaa catctgttgc acctctatcg tacacgagca atgttacaat
    20941 ttaaattagt gcttttggca cgaggaggat attattatgg aaaacggaac agtaaaatgg
    21001 ttcaacgctg aaaaaggatt tggatttatc tcacgtgaag atggaagcga cgtattcgtt
    21061 cacttctcag ctatccaagg tgacggattc aaaacattag aagaaggtca agcagtgact
    21121 ttcgacgttg aagaatcaga ccgcggccca caagctgcaa acgttgtaaa agcttaattt
    21181 tatctgtaaa tcaaattgat ggtagacatc aatttttacg agagaacaaa gcgagtaaca
    21241 aaaatacctg ccacaagaga caatttctct tgtggcaggt a
//
LOCUS       DAYYEF010000047        20813 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000047 DAYYEF010000000
VERSION     DAYYEF010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.049"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(69..1604)
                     /gene="rny"
                     /locus_tag="ACHA1B_002025"
     CDS             complement(69..1604)
                     /gene="rny"
                     /locus_tag="ACHA1B_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HFM8702774.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDSLEKRENS
                     LESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKSTEEELNH
                     ELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDEMKGRIIG
                     REGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPARIE
                     EMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNVLKHSVEV
                     AKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYKENPVVIN
                     AIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENISNSFAGVE
                     SSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVIRETRATD
                     YAK"
     gene            complement(2015..3064)
                     /gene="recA"
                     /locus_tag="ACHA1B_002026"
     CDS             complement(2015..3064)
                     /gene="recA"
                     /locus_tag="ACHA1B_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008094 - ATP-dependent activity, acting
                     on DNA [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HFM8702775.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(3173..4414)
                     /locus_tag="ACHA1B_002027"
     CDS             complement(3173..4414)
                     /locus_tag="ACHA1B_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HFM8702776.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(4654..5232)
                     /gene="pgsA"
                     /locus_tag="ACHA1B_002028"
     CDS             complement(4654..5232)
                     /gene="pgsA"
                     /locus_tag="ACHA1B_002028"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008444 -
                     CDP-diacylglycerol-glycerol-3-phosphate
                     3-phosphatidyltransferase activity [Evidence IEA];
                     GO_process: GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HFM8702777.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(5441..6364)
                     /locus_tag="ACHA1B_002029"
     CDS             complement(5441..6364)
                     /locus_tag="ACHA1B_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RodZ domain-containing protein"
                     /protein_id="HFM8702778.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(7103..8389)
                     /locus_tag="ACHA1B_002030"
     CDS             complement(7103..8389)
                     /locus_tag="ACHA1B_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFM8702779.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(8382..9650)
                     /locus_tag="ACHA1B_002031"
     CDS             complement(8382..9650)
                     /locus_tag="ACHA1B_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="M16 family metallopeptidase"
                     /protein_id="HFM8702780.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            9902..10363
                     /gene="mscL"
                     /locus_tag="ACHA1B_002032"
     CDS             9902..10363
                     /gene="mscL"
                     /locus_tag="ACHA1B_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA];
                     GO_process: GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HFM8702781.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(10422..10868)
                     /locus_tag="ACHA1B_002033"
     CDS             complement(10422..10868)
                     /locus_tag="ACHA1B_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8702782.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(10961..11206)
                     /locus_tag="ACHA1B_002034"
     CDS             complement(10961..11206)
                     /locus_tag="ACHA1B_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HFM8702783.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(11321..11899)
                     /locus_tag="ACHA1B_002035"
     CDS             complement(11321..11899)
                     /locus_tag="ACHA1B_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFM8702784.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(11976..12506)
                     /locus_tag="ACHA1B_002036"
     CDS             complement(11976..12506)
                     /locus_tag="ACHA1B_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HFM8702785.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(12510..13370)
                     /gene="rlmB"
                     /locus_tag="ACHA1B_002037"
     CDS             complement(12510..13370)
                     /gene="rlmB"
                     /locus_tag="ACHA1B_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006396 - RNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HFM8702786.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(13363..13758)
                     /locus_tag="ACHA1B_002038"
     CDS             complement(13363..13758)
                     /locus_tag="ACHA1B_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HFM8702787.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(13755..15167)
                     /gene="cysS"
                     /locus_tag="ACHA1B_002039"
     CDS             complement(13755..15167)
                     /gene="cysS"
                     /locus_tag="ACHA1B_002039"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004817 - cysteine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006423 - cysteinyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HFM8702788.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(15164..15700)
                     /gene="epsC"
                     /locus_tag="ACHA1B_002040"
     CDS             complement(15164..15700)
                     /gene="epsC"
                     /locus_tag="ACHA1B_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009001 - serine O-acetyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase EpsC"
                     /protein_id="HFM8702789.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(15786..16025)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(16022..17482)
                     /gene="gltX"
                     /locus_tag="ACHA1B_002041"
     CDS             complement(16022..17482)
                     /gene="gltX"
                     /locus_tag="ACHA1B_002041"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004818 - glutamate-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006424 - glutamyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HFM8702790.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(17652..18809)
                     /locus_tag="ACHA1B_002042"
     CDS             complement(17652..18809)
                     /locus_tag="ACHA1B_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HFM8702791.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(18843..20213)
                     /gene="radA"
                     /locus_tag="ACHA1B_002043"
     CDS             complement(18843..20213)
                     /gene="radA"
                     /locus_tag="ACHA1B_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003684 - damaged DNA binding [Evidence
                     IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HFM8702792.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(20276..20803)
                     /locus_tag="ACHA1B_002044"
     CDS             complement(20276..20803)
                     /locus_tag="ACHA1B_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HFM8702793.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         5483 a         4600 c         3716 g         7014 t
ORIGIN      
        1 gttttttcgt gccttacaaa aaaagaagag ctgtggcttt tgccgcggct cttcttttgt
       61 attttttatt atttagcata atcagttgca cgagtttccc gaataacgat tactttgatg
      121 tgtccaggat aatccagttc ttcttcgatt cgtttacgaa tatcacgtac taaacgaaca
      181 gcgtctaaat ccgagatttc ttctggcttg accattaccc gaacttcgcg tccagcttga
      241 actgcgtaac ttgattctac accggcgaag ctgttcgaaa tattttccag acttcttaaa
      301 cgacggatgt agttttctaa tgattcactt cgcgcaccag gtcttgctgc tgagagcgca
      361 tctgctgcag ctacaaggac agagataaca gaagtagctt ccacatctcc atgatgagaa
      421 gcgatcgcgt tgattactac tgggttttct ttgtacttgg cagctaattc cgcaccgatc
      481 tcaacgtgag atccttcaat ctcatggtca agtgctttcc caatatcatg gagcaacccg
      541 gcacgttttg ctaattggat atcttcgcca agctctgctg ctaagatacc agctaatttt
      601 gcaacctcga ccgaatgctt caagacgttt tgtccataac tagttctgaa tcgcagacgt
      661 ccgatgatct tgattagatc tggatgaagt gtatgagcac cgacttcaaa cgctgcctct
      721 tccccgtatt cgcgaatacg ttcatccatt tctttacgag atttctcgac catttcttcg
      781 atacgcgctg gatggattcg tccatcttgt atcagttttt ccaaggtcat ccgtgcgatt
      841 tctcttcgga ttggatcgaa tccggaaaga acaactgctt ccggtgtatc atcgatgatt
      901 aaatcgatac cagtcagcgt ctcaagcgtt cgaatattac gaccttctcg tccaatgata
      961 cgacctttca tttcatcatt cggaagggta acgactgaaa cagtcgtttc tgaaacttga
     1021 tctgctgcgc agcgttgaat cgctaatgat aataagtttt tcgctttgcg atctgcttct
     1081 tctttggcac gctgttcaga ttcttttacc attagagtta actcatgatt cagctcttct
     1141 tcagtcgatt tcatgatgac atctcgtgcg tcctcttttg ataaaccagc aattttttct
     1201 agttcttttt gttgatcttc aatcattttt tcaacgtctt tttctcgctc ttcaattaat
     1261 tgctgttttg aactaagtgc ttcttcttta ctttcaagtg agttctcgcg tttttctaac
     1321 gagtcatctt tacgattcag cgtttgttcg cgttgaatca aacgattctc ttgagatttt
     1381 aattctaact tactttctct cagctcactt tcaacttcag aacggtattt ctgattttct
     1441 tccttagctt ctaacaatgc ttcttttttt gcactatcga tgattccagc agctgatgat
     1501 tgtgcaccag ctatttcttt ctcgtgacgt gactttgcga ccataaaccc taaaccaaga
     1561 ccgacaatta aaccgatgat agcgaggaga atgttgaata ccataaaatc cacctccata
     1621 ctatcttttt catttttatc atctatacag cttctatgat aaattattct aaactcgtca
     1681 atatgcatct tcgcatatat gtgtacaaaa aacatgcaca actttattct aatgtttgta
     1741 ccccgtagtg tcaactttaa ataaacaaag aaacggcttt ctacttattc attaaacgat
     1801 ggtttttaaa ataaatgaca ctagtttcat ataggtaaac ctttaaattg agaaactttt
     1861 ctattaaatt attctttgta gatgaacaga tatttttatt ttatgtaccc actcgtataa
     1921 ttaaataact cacgatttct ttattcaata aaaaaacggc aggtcaagga gagtacctac
     1981 tcttcagacc agccgttttt gtttatcata atttttattc ttctactaaa ggcaattctt
     2041 cttgtccttt ttcatcttct gggacagcga cttcttcacc aataccataa gctgctctaa
     2101 ctagagcaga aacttctgcc atcatttcag gatgattagc catatagatt ttagcgtttt
     2161 cccgtccttg accaatccga tcttctttat aagaatacca agcaccgctt ttatcaacaa
     2221 tgtctttttc tactgccatg tctagaagtt ctccttcttg tgagatccct aaaccataca
     2281 tgacatctac ttcagcgatt ttgaaaggag gtgctacttt gttttttacg actttgatct
     2341 ttgtacggtt accaacaata tctgtacctt gtttcaattg ttctgcacga cgtacttcca
     2401 aacggatcgt tgcgtagaat ttcaatgcgc gtcctccagg agtgatttct ggattcccaa
     2461 acatcacgcc tactttttca cggatttggt tgatgaaaat agcgattgtt tttgttttgt
     2521 tgatcgaacc agagagttta cgcaatgctt gagacatcaa acgtgcttgt aacccgacat
     2581 gtgagtcacc catttcgccg tcgatttctg ctcgtggaac taaagcagca actgaatcga
     2641 ctactacgat atctacagcc ccacttgata ctaaagcatc agcgatctct agaccttgtt
     2701 ctcctgtgtc aggctgtgaa agaagtagtt catcgatatt cacacctaat ttttgtgcat
     2761 attgcggatc taacgcatgc tcagcatcaa tgaaagcggc cgttccgcca tttttttgta
     2821 cttctgcaat agcgtgtagt gcaactgttg ttttacctga actttcaggt ccatatactt
     2881 cgatgatacg tccacggggg taaccgccga cacctaaagc gacatctaac gcaagagagc
     2941 cacttggaat tgtagagatt tgttggtcga ttttttcgcc caatttcata atagagcctt
     3001 taccatagct cttttcaatt tttttcagtg cagcatctaa ggctgcttta cgatcatctg
     3061 ccaatacgat aatcctcctt atatttacaa atcagagcaa catttcatta tccttatcat
     3121 atctttttta gtgaaaaaaa gcaagaaaaa accgaacaaa tattcgcatt tatcattttc
     3181 ttaaaagctg ttttctcaaa agatcaaatc cttgcataac cgcattatat ctgatagcag
     3241 cacgatctct ggcaaagtga tatttttccg aaaccacgcc gtctttagat gaaatagcga
     3301 tccatactgt tcctgcagat tgaccttcta acgtgtccgg tccagccact ccggtgaaag
     3361 ctacactgta atctgttctt gctatctcac gtgcttgaat ggccatctgc tccacacatt
     3421 ctttgctgac tgttccatat tctgctaata gctccggatc aatctccaga aaaccagctt
     3481 ttgtttggag cgagtaggta acgaatccgc ctggaaatac ttcagataca ccagcaatgt
     3541 cgcctaatgc ggcttggaag gcgccggctg tcaaactttc cgctgctgtt acagtctgct
     3601 tgttttcttt cagtagttcc actacgactt ttgctagcga attatcatcg ccgtatccat
     3661 aaaaatattc ccctactcgt tcttggattt tttcttctaa tgctaaaaga gcttgattcc
     3721 ctgcctgaac atcatttgtt ttcactgtca gtcgtaatgt cacttcattt ggtttggcat
     3781 atggtgcgat cgttggattg atctgtgtct caatcagatc ttttagctca gtgaccagtc
     3841 gcgattcacc aatcccataa aagcgcaaaa ctttagaaat tagtttttct tcagaaggaa
     3901 aacgttcctc tagtaaagga cgtacttgtt ccacaaacat tggtttcaac tcattaggcg
     3961 gaccgggaag aaggatatac gcatgtgtat ctgtttgata aaaagtccct aaagcaagcc
     4021 ctgtacgatt tggtagagga accccgcctt cgataatctg ggactgttgc agattgtttt
     4081 tggtcatttt tcgatgggtt gtttcaaaat atgccaataa ttttttgtat ccttccgtat
     4141 tttgtatgag agacttaccg aggtgagccg cagttgcttc ttttgtcagg tcatcttctg
     4201 tcggtcctaa tccgccacat aagagtatga gttcacttct tgtttcagct agagcaatca
     4261 actcttctaa acgctgctga ttatctccta caactgtttg ataataaact tcgataccta
     4321 gatcagctag ctgttctgac aagaaagtgg cattcgtatt cacgacttgt cctagtaaaa
     4381 gttctgttcc gacagctatt atttctgctt tcattacttc ccgctccctt atatagtata
     4441 cgctgtattt ttatattttt ttatttaaaa agagggcaag gagctgtgac aaaaatcttg
     4501 tcacagctcc ttgttccaaa taaacagtgt tctcctgcca aaacctcggt cataagtcac
     4561 aatatacata aaacatgaaa agctgttttt tgaaattatc ccttgtgact cagagttaga
     4621 cggcaggctc acaacctctc cactaaacga tacttacatt gatcctttga acacaccgct
     4681 gtttttgatg aagtaatcca cacctgaata gatagtaaag atcagacaag cataaagcat
     4741 gatttgatct actggaatac cgatcaggct gaatgggata ttattgataa acagcaagat
     4801 aatagcaacc atttgtgtag ccgtcttgac ttttcccggc caagctgcag ccatgacttc
     4861 tccatgttcg acaagtagta aacgcaagcc tgtgacggct aattcacgac agacaatgat
     4921 cgctactacc caaccagggg cctttccttg gtcaaccaac atgataaaag cagtcataac
     4981 tagcatttta tctgccaacg ggtccgcaaa cttgccaaaa ttagtgacaa ggcctcgcgc
     5041 acgggcaatt tttccatcta accagtctgt gatactagct aaagcaaaaa taactgcacc
     5101 tactagctgt gtgacagcca gtgtggtgtc tcctacgtta aattgtcccc aatctaaagg
     5161 taaacctaca accaaaatga aaatcgggat catacaaatt ctaagtacag ttaatttatt
     5221 tggtaaattc acactatcga ctcctttctt ccctattcta cgtgactatc agcgaagttt
     5281 ccaccgatat tatttacttt tccaaatgaa tttattcaaa ggagtatttt tattgaaatt
     5341 gatctttttg aattaacgaa gaaggaccgc gacacagatt tgtcacgatc cttctttttt
     5401 atacctacaa gtaaacagat gcgtaaacta atttatacga tcattctgcg tattgaagag
     5461 taaggttcac attttttgga ctctgattgt tttcccctgg attaactggt acggattctc
     5521 cattcgcttt gatcgttgca ttgcttgctg caccaatcgt gatggtcgca tttgttgctg
     5581 tttccggtaa cacggtactc tgtgtttcat ttgctgccag tgtcccttga taaacatagg
     5641 cattgtctac tagcacacct aaccatacac gattgacagc agtaaattca agggttacag
     5701 gcttggtagc gtctgtgata tttactgcga tggcactgcc agaatcttct cctgtagcta
     5761 ttgccatttt cttttcttca cttgattttg ttgttgattc tactgtagaa gactctttgg
     5821 tctgcgtgct ttgctctgag gaagaggact cctcgactga tccttctact ttaagcgaag
     5881 aagctgtgtc tccgattatt ggatcagctt gacgatcttg ccaagtcata tagcccacga
     5941 caacgacaat cgccaaagca accaatccta ataaaatgac aggaagactt gtccaaaagc
     6001 gacttggatg cgattcttcc tgatgcattg cttttctaga agtacttact gtttcaggct
     6061 gcggacgttc agggaccgat cctgtcaatt tgcttttccc atcaaaaaca tcgactaaat
     6121 ggtctccatc ttctcctaca gcttcagcgt attgccgaat aaatgcccgc acgtaaaatt
     6181 taccaggcaa ttggtcaaaa tcatcattgt cgattgcttc caaataacgt ttttgaattt
     6241 ttgtaatctg ctgtaattca tctaaagata tttttttatt caggcgtgct tgccgtaatt
     6301 tttctccgat ggtttcaaaa gccactcgtt catcttctcc agtctgtttg attctccgaa
     6361 gcatctgctg ttgcaacgaa agacgttatg tttgggtgct gtgacaaaag tcatgtcaca
     6421 gctccttttt tccgaataaa cattgttctc ctgccaactc ctcggtcaca agtcacaata
     6481 tccaataaat ataagaagct gttttttgaa cttgttcctt gtgactcgga gttaaacggc
     6541 aggctcacga cctctttctt aaacggtgtt caatcagctg ttcctcggta ttagctcaaa
     6601 aaccggcaaa atataaggag atatttttcc gtatgtttct ctaatactca ggtcaaaacg
     6661 ctgatttcac aacctcttcc ttaaacggtg ttcaaaagct tgcatctgcg gtaataagtc
     6721 caaccaagtt aaaaacatta agaagctgtt tttacttggc tgttcttatt acttgatgca
     6781 gggcagcttt ttcacaacct cttggtacac ggtgttccag aagtagcttc ttcggcaata
     6841 agccgaaata tcacaaaaat ttgagaagca attttcgtaa attccttctt atttcttgaa
     6901 gctgaccact tctgtcacaa cctctttgat tacttcgttt gattttattt taatataagt
     6961 tgattaaaag agagcatgat ttgttttatt ttctcactaa tttttccaac acaactaaga
     7021 ataccataaa agctgatttt ggaggaggtt cctactacaa gtctaaaacg aaatttaaga
     7081 cttttcctca taaaatactg gtttattttg gtctcatgta aaactcgctg aaggcctctt
     7141 cacttataaa tgcttcccca gctgccagta cgtctttcat ttggatcgaa tcgatgattt
     7201 caggaagatc aaataaagtt cgatcgccaa ataaactttg cgtaaattga ttggcaatat
     7261 attcgatcga atttaatgat tggaaatatt gtccaagcat tttcttcttc agcaaatcga
     7321 gatttgtttc tgacacttcc ggatcatcag cgaatccaag aatgatttct ttgacttttt
     7381 ctgctgcttt ctctggttcg tccgtatctc cgctgaagtc cgcaaagtga aattcacgat
     7441 ccaagctgaa ttcaaaacca aagctgtcat cgataattcc ttgattgtac atcgctagat
     7501 agtttcgaga agtattgcct aaaatcattt ggaacaacag attgattgct gttttatagc
     7561 gtaacagttc tgttccttct tgcggcaatg tgtctaatcc tttaatacca agtacaaatt
     7621 tatctcgtgt aatggctgct tccaatgcac tttgtttgat gatttctttt gtgttttcag
     7681 ggaaataacg tacaatttct tgctttggag ggaaattttt tgcttcttgg ttttcccgaa
     7741 taagtttcat caatttctca ggctccatct taccaactac aaataaaacc atattgcttg
     7801 gctgataaaa cgtccgatag cacgtataca agtcttgagc tgtgattttg tcgatacttt
     7861 caaccgtgcc cgcaatatcg atatgcaatg ggtgtgtagg atacaagtta tttagtatgc
     7921 caaaaaacat ccgccagtta gggtcgtctt catacatttg gatttcctga ccgatgattc
     7981 ctttttcctt gtttacagtt tcttctgtga agtaaggtgc ttgtacaaaa tcgatcagag
     8041 tcgtcagatt cttttctacc tgatccgtcg tagaaaacag atagctggtt ttcgtaaaac
     8101 ttgtgaaagc attggcggaa gctccttgtt tcccaaataa ttgaaagaca tcaccatctt
     8161 ctttttcaaa caacttatgt tctaaaaaat gggcaattcc atctggaact ttcacctttt
     8221 ctttttcacc atagggaata aattcgttat cgatcgaacc ataattcgta ctgaacaaac
     8281 catatgtctt gtgatagtca tttttaggca acaaatacac ggtcaaaccg tttggcagta
     8341 cttcatgata aagtgtttca ttgatttgct catattctgt tttattcatt tgcatttcct
     8401 cctgctaaaa agaagattgc ctgcaattcg atttgctcag ctacttgttg tatctctttg
     8461 atcgttacgc tctccatacg tttcaaccat tcttcatcag ataattttgt ttccggcagc
     8521 cagctgtcca aaaaagaagc ttcgattgcc gcttgcggag agtctagaga aagcagatat
     8581 tggtttctca gcattgcttt tgtctgagac agttccaact ctgttatttc accatttcgc
     8641 aaactttcta attgctcgtg aatcagatga agtacttgat ttcggttctt ttcatcgata
     8701 ccggtttgga cactcatgaa tcctcggaac gtatccacgc tactagaggc ataataagct
     8761 agactttctt tctctctgac attcatgaaa agtttagagt gaggaaaacc gccaaataaa
     8821 ccgttaaaga ccattagcgc aaaacgttct ggttcatcgt aatacacatt tgtctgataa
     8881 gctaggttca gctttgcttg aacgattggc tcacgtactt gtcgttcctt cacgatattc
     8941 acttgaggtt gggtataaaa cagatctgga taaactgttt cccgcgactc aaatggtaat
     9001 tgcccaactg cttcagctgc tttgtccgga tcaacatcgc cgacaacaaa aatgtcgatt
     9061 tgatcatttg ccatcatttc ttgatagtag gacgctagcg aactagcagt gatcttgtcc
     9121 aaatcttcga ctacgcccaa ccctgggatc ttttgttccg ggctgttttc aaaataaagt
     9181 tcttgcaagg cataggaagc aaaagtttgt ttatcttcct tcaaactttc caaatataga
     9241 cgcagattgt tcttttccaa gtcaaacgtc aactgatcaa actgatgatt tttaatattt
     9301 ggataaaata aaacctcttt taaaaaatct accgcttgag aaaaaaggtt tggatcattg
     9361 acatattcac cattcacaaa actgatccct gcgtttagcc aatgtaaatt tccttttttt
     9421 ctaactgata atccaaagct tgcgccataa agctctgcaa gttgcgcact taactttgtc
     9481 tgatccggat aattcaaact atttgtttcc aacatgctgc tgagaagtga acgtttcgtg
     9541 atgacttctt gttgcagacg cgcagtaaaa cggataaaaa tccggatcgt tttgtattgt
     9601 tttgttggta agacatgaag attcacgcct tctgccaatt gatacaccat atttatatgc
     9661 tccttttcac agttgattgc ccgcttactc ttttaatggg tcaacctgcc ttttttactt
     9721 attcctctgc ttgaaattta taagttcagg caattcgccg ttttttctaa atgatgttac
     9781 actttatagt atagcataga tgttttttat caaaagaaac agacggctaa aagcgtatat
     9841 tgttttttta ttttttattt ttcgatatac taaagacaaa taaaagaagg gagggtcatt
     9901 catgatcaaa gaattcaaag agttcatcat gcgtggagat gtcttggatc ttgctgtcgg
     9961 cgttgttatt ggtagtgcgt ttacaagcat cgtaaaccaa gtggtgcaag gcttgatcac
    10021 accactaata ggttggtttg tcgcaatgat cacaggtact tctgatttag aaggagcact
    10081 ttcaattctt gactggtcgc cgacaaaagg cgtcacattt gcgtttggta acgttattag
    10141 tgctatcatt acatttctga tcactggttt tgtcttattc ttagttgtca aagcggcaaa
    10201 ccgtgcgaag aatttacgct ccaaagaaga gcaagtggaa gtggaagaaa ctcctactgc
    10261 agaagattat cttagtgaca tacgcgatct tcttgccaaa caagtggcag aagacaatac
    10321 acatccagta gagcaaacaa atctttccga tacttctaaa taataaagaa tctaaaaaaa
    10381 agaaagccga ttttcagtgt cggctttctt tttttagatt cttaacttgc tacttgttcc
    10441 tttttcatgt cgatatgtgg aatatcatct tccaaataca catctgagat tgccttgaat
    10501 ccaaacgact cataaaaagc ttgtaggtat tcttgtgcgc cgatcacgat tggtttttct
    10561 ggaaaatttt tctggatcat gttaatcgtt tcttgaacaa tctttcttcc taaaccatct
    10621 ttacggttgt cctgatgaac aaggacacgt ccaaaatgga tactctccgc ttcttcatat
    10681 actcgcgtgt aggcaaggat cttcccatca gtatcttgaa aaaacgtatg ccaagcttgt
    10741 ccatcaatgt catcaacttc ttgataagga cactgttgtt ccacaacaaa aactgcgatt
    10801 cgttctttga cgatcgcgta aaactctgct gttgacaatt cttcaaattt ctttacctga
    10861 tattccacta agcaaacgcc ccctgctttt ttattcttag cataccgatt cgcacacaaa
    10921 aaagcaaacg aaccttacga atctcaggct cgtttgcttt ttaaactgct tcagttaaaa
    10981 attcgatctc aactgtccga gtaagtacat ctgaatagct gtaagatact cgttcaaaag
    11041 aattttcttc aggatccaaa tcaacaacga atactgaagg ataggtttct gttaaaacgc
    11101 cgcggcgttc tgtttgacgc tttcttcctg tctgagcaac caacatgatt gggctgccga
    11161 tacgaccttc taaatctttc ttgattgaag ctaaagttgt tggcatacag ttcacctcta
    11221 ctatcaacta taccacatat ttttaaaatt ttcaagttta ccataaaaaa aaaagaaatg
    11281 caataaaaat aaataagaag ctcattaaga tttttctaaa ttattcctca ttataaaatt
    11341 tcaagtgttt ttttattttg agttttactc tcccgtaagc gctcattact tgcttgtgat
    11401 ccattgctaa acattcagcc atgtctacaa aatcaacgcc ttgcatataa taatgaaaaa
    11461 ttttagcttc tatttttgaa aactggattt cgcaattttc gattgcttct tttaataaaa
    11521 gatgctgaat cgctaaaggt tcttgcaatg tgatctctgc taaaaagtct ggtccttctg
    11581 tctctatttt ttggtcgatt gagacttcat ctttttgatc acgacgcttc agcgcgttct
    11641 gcttcctcaa cagagaatag atttgattgc ttataatgct tttataataa cttccaaagc
    11701 taacaccttt gcttttttcg taagttctca atgcctgata taaagcgatc cttgcttctt
    11761 gttcccaatc ctcagaaaca taatttctta aataataggt gtttttcaaa cgtagtaaaa
    11821 gtggaaaata tttttgatac agggcagcaa atgcttcttc gtcaccatta cgtgcagcgc
    11881 gcaataactc ctcagacata aaataattcc tccataaatt cgtttatgga ggaatcttat
    11941 catcaatgat tcatcgaact gattagaacg atatgttatt tattttttct cattaaatcg
    12001 tccaattttt gggacaattt ttttaactgc tcttcattcc atggagaatt acgtcggaaa
    12061 tcaataaaat gcatatcttt attttcttgg gctattgttt tttccgtttt ttttatcgtc
    12121 ttatataatt cataagcaga agttcgtaat gctccttggg aaaagatcat ccactgttct
    12181 gctaaatcgc ttgtcgccac tgtcacttgt gtcaaacggt cattcagctg accagcgatt
    12241 ctctcgatat aactgtcagc cgtttcgtct tctttcgtaa aaacaacatc caactggtat
    12301 ttcttataat tttgttggat gcccggaact agttgggcat cgaagacaac gatgacttcc
    12361 attccttcat atttcgcata atttgataaa cgatgtaaaa gagcttctct tgcatccgcc
    12421 attttgtcct gctttttaag ctggacaagt tccggccacg aaccaatcat gttgtagccg
    12481 tctacaatca acagctgttt tttcatggtc tactccccct gacgttggga aaaagcctga
    12541 tacataagca aaccagcagc aacactggca tttaagctct ggacgtgccc ggtcatcggg
    12601 atcgtcagca attcatccat ttcttttttc aatcctggac tcattccttt gccttcatta
    12661 ccaatgacta aagcaattga tcctttggca ttccattttt ggaagtttgt gccggtcata
    12721 tctgtgccaa atacccaaaa tcctgtttct ttgagctgtt gcacagcttg taccaaattc
    12781 gtcacgcgtg caacagggac atgttcgact gccccagtgg aagtctttgt tacgataggt
    12841 gtgattccaa ctgctcggtg ttttggtatg atcacaccat cgacgccact tgcgtctgct
    12901 gtccgtaaaa tcgacccaaa attgtgtgga tcttcgatgc tatccaaaat caaaaagaag
    12961 gggtcttctt ttttctcttt tgttcgttca atcagttggt caagggataa atattcataa
    13021 ggtgtaatcg caagaacgac tccttgatgc acgccgtgat cgctcaaagt ttctaatttt
    13081 tgtttaggaa cccatttgac tggcacagct tgttcacgtg cgatttcttt cagttcttct
    13141 actttttctc ctcgtgaatc ttcttgaaga aagagtttat tccctcgccc ttgttgtagc
    13201 gcttctactg cggcatggtg cccaaagacg aaattatctt ctaatgcttc ttcattttga
    13261 tcagaaactg actgatttcg tccagtttgc tttttatttg aatatctatt ttgttttttg
    13321 tcttcaaatc cacgtttcga ttgatgtttg tttgttcttt ctttacccat ttttttcacc
    13381 aactttctga atacaccagc ggatcaattc ttccatccgc tcggtttgtt ttgtcaaatg
    13441 cagatagccc atgagcgctt cgaaccctgt tgcgacccga tacgtcgtaa catcagcatt
    13501 ttttgcgctc gtatggcttt tagcatttct tcctctgcga taataaagtt cttcttcttc
    13561 tgtcaaaaga tgttcttcca gcatttgctg aatcaaaaag gcttgtgcat tcgcagaaac
    13621 ataattcgtt gccgcacgat gcagcttatt gggttttgtt tctccttgat caatcaggtg
    13681 gtcacgaaca tagatttcgt aaatcgcatc tccaacataa gccaaggcta aaccgttcaa
    13741 ttgtgtgtaa tctctcatgc ttctcttctc catcgggttc cttgcggtgt atcttctaat
    13801 aagatccctt tttctttcaa caaatcacga atttcgtcgc ttcggacaaa atcacgattg
    13861 cttcttgctt gatttcgttc ttcgatcaat tgttcaatct cttcatctaa taactcttct
    13921 gctgtaaata aaataccgaa gatcgaaagc cattgcgaga ataaagcttc tccttgtgcc
    13981 aagacagcgg cagaaacttt cggctggtct agataagtgt tcagccactt agcaagctca
    14041 tagaccactg tgatcccatt tgctgcatta aaatcatcgt ccatttcttc gatgaatcgc
    14101 tgttctaaat tttctaacaa agcgatttta tccgcatcat ctgccaaatt ctctgaggca
    14161 gtttcttggc ggaatttcaa attgtcaaac gtattcttca gtcgttgtaa attggtggct
    14221 gcttctttca tcgtcgtttc actgtagcgg atcggacgac ggtattgtgt ggtcgccatg
    14281 aagaaacgca agacttgtgg atcaacgttt ttgatcattt catgtacagt gatgaaattc
    14341 cctagagatt tactcatttt ttcatcgtct tcgccaatcg ttacatagcc attgtgcatc
    14401 cagtaattag cgaatttttt ccctgttttc gcttcacttt gtgcgatttc attttcatga
    14461 tgaggaaatt ctaaatcttg cccgccacca tggatatcga tcgtttctcc taaatgtttt
    14521 gttgccataa cggaacattc aatatgccaa ccgggacgtc ctttgcccca tggtgaatcc
    14581 caagaaatct cgccaggttt tgcttgtttc cataaagcga aatctaatgg gtcttctttt
    14641 tgctgctgtt cttcccctgt acgctgactt gctccgactt ccagttcatc gatggattgg
    14701 tcacttaatt tcccataatt ttcaaattta cgggtacggt aatacacatc acctgaagat
    14761 tcataagcat agcctttttc aaccaacact tgaataaatg ctaaaatatc tggcatatga
    14821 tccatgactc ttggatgcag tgtagcaggc tcgacattca acgctttcgt atcttcttca
    14881 aatgctcgga tgaaacgatc agcaacttct ggtgctgtaa tacctaattc gtttgctgta
    14941 cggatgattt tatcgtctac atccgtgaaa ttcgatacga aatcgacttt atagcctcga
    15001 tattcaaaat agcgtcgaat tgtatcgaaa gcaatggtgc tacgagcatt tccgatatgg
    15061 atataattat acacagtcgg tccgcagaca tacataccga catgtccctt ttgtataggg
    15121 atgaattctt ctttttttct ggtcaatgta ttgtagattt ttatcattct gatctcctca
    15181 ctttttctcc tttgattcga acgacttttg ctggtactcc taccgctgta gcgtcgtctg
    15241 gaacatcttt caacacaacg gcacctgcac cgattttggc gttttttccg atcgttaccg
    15301 gtcctaatat ctgcgcattc gcagagagca tggctccttg tttaacagtt gggtgtcttt
    15361 tacccgtttc ttttcctgtg ccgcctaatg ttacgccatg gaataaaatc acatcgtcct
    15421 cgatttctgc ggtttcgcca atgacgattc ccattccatg gtcgatgaac acgccagttc
    15481 caatcgttgc tcctggatgg atctcaacac cagttaggaa acgccagaat tgagcattga
    15541 tcttcgccaa taaaaagagc cggtgctgat ataaaaaatg agagaaacga tgccaaaaca
    15601 aggcatgaaa accagggtat gtcaaaacga tctcagctgt cgaacgtgca gccggatcgt
    15661 ttctctttgc tgcatcaatc gctcgggtaa accaactcat gactttccac tcctttcgta
    15721 agaattttat gtaggaaatc atcttcttat aaagaaaaga agcgcctttt aaataagttt
    15781 ccttatcaaa agacgctttc cgcgtggttc cacttttctt cataatcaat gattatctct
    15841 gacagctaac gcctgttata cgttcttggc tactttgttt cctataaaac agtttttcct
    15901 gttttctgtg tttcgccaag accactccca gaggcatttc ggcaaccatt cattgatacc
    15961 ttgcaccacc cggtatctct cttgtaatga tcagctgctt acttttttct gttcatcgtg
    16021 tttagttcag tacttgattt aaatgtgcta atgatttttc acgaccaagc aattcgatcg
    16081 tttcaggcaa ttctggacca tgcatttgtc ctgatacagc tacacggatt ggcatgaaaa
    16141 gattttttcc ttttacgcca gtttcttttt gaacagcttt gatggcagct ttgacagttg
    16201 gagcatctac tacttccatt tgttctagct gtgctttgaa tgcgtggaga acagtaggaa
    16261 ctgtttcacc agcaagtact tcttttgctg cttcattcaa tacaggatgt tcattgaaaa
    16321 atagcgtaga cagatcaacg atttctgcag catagctcat ttgaggttga tacaggctaa
    16381 cgatcttctt cacccattcg attgtctttt catctgggtt ttctgctaca cgtccatcag
    16441 cgattagata aggcagacac atgtcagtaa atgcatctag atccattgct ttgatgtaat
    16501 ggttgtttac ccattgcagt tttttcgcat cgaaagctgc gggtgattta cttaggcgtt
    16561 ttggatcgaa cattttgatc aattcttggt gttcgaagat ttcgtcttcg cccacaggtg
    16621 accagcccaa taatgcaata aagttgaaca ttgcatctgg tagatagcct aattcgcgat
    16681 attgttcgat aaattgcaag attgattcgt cacgtttgct tagtttttta cctgtttcac
    16741 tgttgatgat caatgtcata tgtccgaagg ttggtggtgt ccagccaaat gcttcataga
    16801 tcatcagttg ttttggtgta ttggcaatat ggtcatctcc acgtaaaacg tgagtgattt
    16861 tcatcaaatg atcatcgacc gcaacagcaa aattataagt tggcatacca tcgcgttttt
    16921 gtatgacaaa gtcgccaccg atattatcgg attcgaacga aatagcgcct ttcaccatat
    16981 ctgtaaatgc gtattctgta ttgcgaggca cacggaaacg tacaacagat tctagacctt
    17041 gtgcttcttt ttctgcttgt tcttcaggtg tcaagttcgc acatgttcct gcgtaatgag
    17101 gcatttctcc tcttgcgcgt tgtgcttccc gttctgcttc taattcttct tctgtgcaat
    17161 agcatttgta tgctcgattg ctagcaagca gctgatcaat cagcggttga tagatttctt
    17221 tacgttcaga ttgacggtaa gggccgtatt ctccaggatt ttcaggagat tcatcccaat
    17281 tcattcccaa ccaagcaagg ttttccaact ggcttttttc gccatcttcg atattacgtt
    17341 tttggtcagt atcctcaata cgaataataa agtctccatc attgtggcgg gcaaacaaat
    17401 aattgaataa tgcagttctt gcatttccaa tatgcaggtg cccagttgga cttggtgcat
    17461 agcgtacgcg tactttcgtc attttcttcc tcttctttca aactagactt tgactaacag
    17521 caaaaattcc gtcagttacg gcttctcaaa tatcatttat ttaaagccac tcagcacaaa
    17581 ttttaccttt tctaaggtaa atagtaaagc caactggttg aatttcctta ccagttggct
    17641 gaatttcttt tttattttga ttgtttagtc tttttctctg tctctttttt attgtcgatt
    17701 cctcgtcctg catgtgcagg tttagcaaag atcatgcgtc cagcagctgt ttgaagggca
    17761 cttgttacaa cgacttcgat acgttcattc atgtaatgct gtccatcttc tacgacaacc
    17821 atcgtgccgt catcaaggta ggctactcct tgttggcgtt ctgtcccggc ttttactact
    17881 agaacattca tcgtttcacc agggatgacg actggtttta cggcatttgc caacgcattg
    17941 atattaagaa caggtacatt ttggaattca gagactttat tcaagttata gtcattggtt
    18001 acaatgacac catctaaaag cttagccaat ttgatcaatt tgctgtctac ttcactgata
    18061 tcttcaaagt ctccatcgta catttcgaca gatataccct cttctttttg caaggcattt
    18121 aggatatcta atccgcgacg accacgcaca cgtttcaaac tatcccctga gtccgcgatg
    18181 tattgtagtt cgtaaagaac aaaattaggg atcatcaagg ttccttctaa gaatccagtc
    18241 tttgtaatat cataaatccg accgtcaatg atcacgcttg tatccaagat tttatattta
    18301 tggaaatttt ctcctgattt tcgttctaac agttgactct caacttgact agctgtttct
    18361 tgctcgattt ttttgcttcg tgaaccaaaa actttcttcc attcttcgat tcgtgtcgtt
    18421 cccattctca atcccagata gcctaagatg atcatcagta aaatcggcaa tacactattg
    18481 acgaatggaa tttccatatt gtaaagaggg gtcgagatca caacacctaa agtcaatccg
    18541 atgatcgcac cgatcgcacc gaagagaaga taagtcaagc tgacctcact tagtttttgt
    18601 tctacttgtt tgataatagc tgagatatgt ttggccaaca gcaaagataa taaaaagaaa
    18661 ataagtgcgc ctaacaggct gttggtaaat gtattattca gccatccgtt tgactgttga
    18721 ccgattgcct gccaagctga gggtaaaaat gaaataccca agcttgcgcc gacaatgatc
    18781 atcagcaaag taatgacacg tttttgcatc gtttttcctc cgtttcgaca atcatttatt
    18841 agttagcgga acacacgctt caacgtttca gccaaagttg ctactccaac tatctcgatt
    18901 ccttttggcg cttcccagtt acctaagttg tttttaggta ggtatacttt tgtgaagccg
    18961 agtttttgga cttctttgac tcgttgttca atatgactga cacgtctgat ttctccagtc
    19021 agtccaattt caccgatgaa acattccgtt ggctgtgttc ctttttcttt atagcttgaa
    19081 gcaatactga cagcgatagc taaatcaatc gctggttcat ttaattttac cccacctgca
    19141 gcttttaagt aagcatcttg attctgaaga agcaacccag ctcttttttc cagcactgcc
    19201 atgatcagag atacccgatt gaaatcaaga cctgttgttg ttcgtttggc atttccgaac
    19261 atagtaggtg tgactaatgc ttggatctct accaaaattg gacgtgtccc ttccattgcc
    19321 acaacgatag cagagccagt tgcaccgtct aggcgttctt ctaagaaaat ctgtgaagga
    19381 ttagcgactt cttccaatcc atgctcatgc atttcaaaaa tcccaatctc attcgttgag
    19441 ccaaatcggt tttttactgc tcgcaaaatc cgaaaactat gatgttgttc accttcaaaa
    19501 tataacaccg tatccaccat atgttctaac attcttgggc cggcgatcga gccttctttg
    19561 gtaacatgac cgacgataaa aatggctatc ccatttgttt tagcgatttt gagtagttct
    19621 gcagtggttt ctcttacttg gctgacactt cctgccacac ttgtgatgtc tggctgcgtc
    19681 atcgtttgga tggaatcaat gataacataa tcaggggaga tatgttcgat ggcacgactg
    19741 atttcgttca tatctgtttc agcgtataga taaaattctg tgttgatact tccgaggcgt
    19801 tccgcgcgta attttatctg ctctgcgctt tcttcgccgg atacatataa gacttttccg
    19861 cctatggctg ctaattgctg agaaacttgt aacagcaaag tggatttccc gatacctgga
    19921 tcgccaccaa tcaagaccat agaccctggc accacacctc cgcctaacac acggttcagt
    19981 tcttctaatt ttgttttgat ccgaggttct tttttaggga cgacgtctgc gatttttgtt
    20041 ggttttgctt tttctcctgt caaacttgtc cgagttctgc ggtccgttgt atcttgttcg
    20101 atttcttcga ccatcgtatt ccattttccg caatttgggc agcgtcccaa gaacttaggc
    20161 gacacatacc cgcaattttg gcaaacaaat tgtacttttg atttttttgc cattgtaccg
    20221 cctcctttta tcctaatcat gagacattaa atcaagctta agtatcttta acgttttatt
    20281 tactggaaga accaaatccg ccttgacgtt gagcagtcgt ttgatcttga tctgctttta
    20341 aaaacggcaa aaagatccct tggccgatac gctcgccttt tttgatcact acatccttga
    20401 aaccaaagtt ggtgaattgg aacatgatat ggccttcatt tgcctcatta ttgtaataat
    20461 cactgtcaat cacacctact ccgtttgtca acactaaaaa ccgcttcaac ggattgcttg
    20521 aacggttagc aagctgcaaa aattcatctt ctcccatgta agctttgatt ccagtaggca
    20581 cgagggttgg tttcaattgt ttttcatttt ctgatacatc ttttttcaat ccatctgcga
    20641 ctgtttccaa cccctttttc cagcctgctt tccagatact tggaatcacg acctcttctg
    20701 ctgcttcaaa atcatagcca gcagcatgat gtgtagcgcg ctgcggtaga ttgatatttt
    20761 gatctttata tttagaaata acttcaaatc ctctttttct caccggtttt cct
//
LOCUS       DAYYEF010000048        20183 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000048 DAYYEF010000000
VERSION     DAYYEF010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.050"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            210..1016
                     /gene="proB"
                     /locus_tag="ACHA1B_002045"
     CDS             210..1016
                     /gene="proB"
                     /locus_tag="ACHA1B_002045"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HFM8702794.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1013..2260
                     /locus_tag="ACHA1B_002046"
     CDS             1013..2260
                     /locus_tag="ACHA1B_002046"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004350 - glutamate-5-semialdehyde
                     dehydrogenase activity [Evidence IEA];
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HFM8702795.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2336..2680
                     /locus_tag="ACHA1B_002047"
     CDS             2336..2680
                     /locus_tag="ACHA1B_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702796.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2797..3123)
                     /locus_tag="ACHA1B_002048"
     CDS             complement(2797..3123)
                     /locus_tag="ACHA1B_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702797.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3496..4698)
                     /locus_tag="ACHA1B_002049"
     CDS             complement(3496..4698)
                     /locus_tag="ACHA1B_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM8702798.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4815..5330
                     /locus_tag="ACHA1B_002050"
     CDS             4815..5330
                     /locus_tag="ACHA1B_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFM8702799.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5529..5975)
                     /locus_tag="ACHA1B_002051"
     CDS             complement(5529..5975)
                     /locus_tag="ACHA1B_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFM8702800.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6022..7500)
                     /gene="msr(C)"
                     /locus_tag="ACHA1B_002052"
     CDS             complement(6022..7500)
                     /gene="msr(C)"
                     /locus_tag="ACHA1B_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFM8702801.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7854..8483)
                     /locus_tag="ACHA1B_002053"
     CDS             complement(7854..8483)
                     /locus_tag="ACHA1B_002053"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFM8702802.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8467..8931)
                     /locus_tag="ACHA1B_002054"
     CDS             complement(8467..8931)
                     /locus_tag="ACHA1B_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFM8702803.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9418..10686)
                     /locus_tag="ACHA1B_002055"
     CDS             complement(9418..10686)
                     /locus_tag="ACHA1B_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFM8702804.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10917..11654)
                     /locus_tag="ACHA1B_002056"
     CDS             complement(10917..11654)
                     /locus_tag="ACHA1B_002056"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFM8702805.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11721..12290)
                     /locus_tag="ACHA1B_002057"
     CDS             complement(11721..12290)
                     /locus_tag="ACHA1B_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFM8702806.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12418..13290
                     /locus_tag="ACHA1B_002058"
     CDS             12418..13290
                     /locus_tag="ACHA1B_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFM8702807.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13632..14504
                     /locus_tag="ACHA1B_002059"
     CDS             13632..14504
                     /locus_tag="ACHA1B_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFM8702808.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14501..16459
                     /gene="nagE"
                     /locus_tag="ACHA1B_002060"
     CDS             14501..16459
                     /gene="nagE"
                     /locus_tag="ACHA1B_002060"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFM8702809.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16710..17561)
                     /locus_tag="ACHA1B_002061"
     CDS             complement(16710..17561)
                     /locus_tag="ACHA1B_002061"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFM8702810.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17684..18151
                     /locus_tag="ACHA1B_002062"
     CDS             17684..18151
                     /locus_tag="ACHA1B_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFM8702811.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18414..18896)
                     /locus_tag="ACHA1B_002063"
     CDS             complement(18414..18896)
                     /locus_tag="ACHA1B_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFM8702812.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18996..19859)
                     /locus_tag="ACHA1B_002064"
     CDS             complement(18996..19859)
                     /locus_tag="ACHA1B_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFM8702813.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6068 a         4157 c         3662 g         6296 t
ORIGIN      
        1 actactccta ttctaacata tccgaggctg taaaagactt tctttacaaa ttcttcaaga
       61 aattctgcta tcttaaagta aaccattaat tcgttctttt tccaaacgac tacaagttgt
      121 acaaaaaaac tattttttac atgactttac tcgtcaaaac aagtagaata gaacgaaatt
      181 aatgagtgga tatttgattg aggtgtcaca tgcgtaaaga aattaaaaat gcaaaacgaa
      241 ttattgtcaa agtaggaaca agtacattga tttatcccaa tggaaatatc aatcttgcgg
      301 caatcgatca gttagctttt gtcctttctg atcttagaaa tcggggaaag gaagtgatct
      361 tagtctcatc aggagctgta ggcgttggta tgcataaatt acatttgtca gaacgtccga
      421 ctttgattcc tgaacagcaa gctgcggcgg ctgttggtca agccgaactg atgaatatct
      481 ataatcaaag attcagtgta tataatcaac agacggcaca gatcctcgtg acaagagacg
      541 tggtagatta tcctgaaagt cgtaaaaatg tgaggaatac attggaacag cttttgatta
      601 tggacacgat ccctatcgtg aacgaaaacg atactgtagc agtggatgaa ttagatcatc
      661 tgacaaaatt tggcgataat gatcagctgt cagccatcat ggcaaaactt gtcgcggcag
      721 accttttgat cgtcctttct gatatcgacg ggttttattc agataatccg actacaaatc
      781 ccgaggctca gatgtatcgc tatatcgata aaatcgatga aaagattctg gcacaagcag
      841 gtggtgctgg tagcacattt ggaacaggcg gtatgcagag taaattaaaa gccgcttcta
      901 ggatatttga agcaaacagc gcaatgattt tagcaaatgg aaaaaatccg gcaattattt
      961 ttgatattct tgcaggaaaa gaagtaggta ctttatttaa ggaggacttg aaatgactga
     1021 cttgatgcaa ttaggacaac aggcaaaaga tagcgcgcaa caactagcac ttatgcctac
     1081 aaaccgcaaa aatgagctac ttgttcaaat ggcacaaacc atcaaaaaga atcaacaagc
     1141 gatcattgaa gcaaatcata aagacttaga aaaagcagtc gaaaacaata tcagtgaaac
     1201 gatgcaagac cgcttgcagc tgacacctga gcgaatcaat gccatggcta cagagatcga
     1261 aaaaattgct tcgttagacg atcctattgg aaaagtagat gagatgtgga cgaacaccga
     1321 cggattgaga atcggcaaaa agcgcgtgcc actaggcgtg accggcatca tttacgaatc
     1381 tcgtccaaat gtcacgacag atgcagctag tctagcattc aaatcaggga atgccgttat
     1441 ccttcgcggt ggcaaagaag cattcttctc gaatcaatta ttagtccaat tattgcagca
     1501 agtactggtc agtgctggcg aatctcctta tgccatccag tttgtcgatg atacttctca
     1561 tgaaactgca ggacagttga tgcgattgac agaatactta gatgtgctga ttcctcgagg
     1621 cggagcaaaa ttaatccaac gagtcaaaga acaggcaacg gtacctatca ttgaaacagg
     1681 tacaggaaat aatcacgtat atatcgataa agaagcacag ttatctatgg cagtgaacat
     1741 catcgtcaat gcaaaagctt cccgtccatc tgtctgtaac gcggcagaaa cattgctgat
     1801 ccattctgag atcgcacctt ttttcttgcc agctattgaa aaagaactgg tagaacacgg
     1861 ggtctcttta cgtgcggatg ctcgtgcgtt agaatatcta gagacggctg ctttagcaga
     1921 agacacagat tgggatactg aatatctaga ttatatcctt gctgtcaaag tggtcgattc
     1981 tttggatgaa gcaattgcac atatcaatcg gcataatact aaacattcag aaacgatcgt
     2041 gacagatagt tatgcggcta gtcaacgttt cttaaatgaa gtggacgcgg cggctgtcta
     2101 tgtcaatgcc tccactcgtt ttacagacgg atcggtattt ggttttggtg cagagattgg
     2161 tatctctact caaaagttgc atgcccgtgg tccaatgggg ttaaatgaat taacttccac
     2221 aaaatatatc atttatggcg atggacaaat ccgcgaataa tgtttcgtgt gaaacattat
     2281 tcccgccttt tgcctttttt ctgtaaaggt tctatccaac tagaaaggtg tcaatatgtt
     2341 tgaaatttta atgatttttt ttatttacct tatttctctg aatatcgctg cttttctggg
     2401 agtcggtatt ttatcccttt tctttcaatt caaaaaacga agcataggga gtcaacggga
     2461 aaaatggtcg cagtattttg acaaaatcgg gcaaaaaggg ctggttacac gcttgcacat
     2521 tagttacatg gttgcattat gcttattagc gacaatcaat tactattctt ttttcgatca
     2581 ttcaatcgct tatacgatta cgctactgat tgctgggatt tttcacttat cttataaata
     2641 tcagctgaat aaaaaccact tgaatcggac tttccgctaa aaaatatccg tacgataagt
     2701 agagtgcctt gaagatcggc aaaaaactgc cggacttttt agaggctgtg acaaagattt
     2761 tgtcacagcc tctttttcca tataaacggc gttcgcctac cagctgcctg gtaaatctgt
     2821 ttcctcttcg ttaagaagcg aaaatccgtc aaatgtttcg ccatcataat aacgaagcag
     2881 ctcatccatg gacaagttca tcgttttttc tttttcttct tccgctgatt cagccagtag
     2941 ctgttcccga tacacctgat acataccagc tattttttgc tgcatcgctt ttctagtttc
     3001 accttccgca ttgattattg gcaattcttt gatatagcca cgataaatca accgatcatc
     3061 tgaaaattca atgggtaatt caacgagtgt caacccgact tcctgaaaat attcttccag
     3121 catctattat ccccccattc tttttcttaa atgaatttta gcttacctac tgaaaatttt
     3181 ccagtttcat tattttgaga aaaaaaggga atgtgacaaa aatcgtgtca catccccttt
     3241 ttccgaataa atggtgttct tctgccaact cctcaatcat aagtcacaat attcaacaaa
     3301 catgagaaac tgttttttga aattgttcct tgtgattcag agttaaacga cagtctcaca
     3361 acctcttggt aaacggcgtt caaaagcttg catctgcggt aataagccca accaaacgaa
     3421 aaatatgaga agctattttt gtttggctgt tcttatgact tgatgcagga cagctttttc
     3481 acaacctctg atttcttatt cttcttcatt tgtagcaaaa taattacggt gataaatgat
     3541 acaacataca ctgataagaa caatggcacc tgcaaaataa aacgcatagc tttcaccaat
     3601 atgttcacca atcacacctg caataaatgg tgctaaagct ccaccgaaaa agcggacaaa
     3661 actatagctg gacgaagcaa cgtttcgttg cagacctggt atttccatag caatcgtcgt
     3721 caacagtgta ttgataattc cttggaaaaa tcctgctaac acaatgctga tcggtacaag
     3781 gactggcata gaagttccag ctcctaataa cagcaaacaa ataatgaata agacaaatgc
     3841 tgctaaaatt gtccgataag tcgtaaactt ccgctcaaga gccggtgcaa cgaaaatcga
     3901 agcaatagcc agaagcacac cccagccaaa aaatacaaaa ccgacttcta attcagaata
     3961 gccaatcaat aaaaatggcg catacgcaag taaagtaaag aatccgaaat tatataacaa
     4021 tgcgattagt ccaactgaac gaagtttatg attgcttaac gctttgacac cttcccaaag
     4081 gcctactttt ctctttggtt tctcagtttc aggtaaaagt accgctaggg ctataaaacc
     4141 gcaaaacatc aaaaatgcta ccccaaaaaa tggataacgc catgaaccac tgcccaagac
     4201 cccaccgact agagggccaa cagccattcc gcagccaagt gctgcttcat acatcatgat
     4261 tgctttttct gtgttaccaa ctaaaatact gacgatcgtt gctaaagcag tagagacaaa
     4321 taaagcattc ccgacacccc agccggcacg taacccaatc agcattccga tattcccaga
     4381 taatccgcca agaccagcga atacaacgat gataaacaat cctgtcatca atgttttttt
     4441 caaaccgatc cgactagata agaaacctgt aaatagcatc accacaccag tgactaacat
     4501 gtaactagta aataacaggg tcgtttcagc tggcgtagcg tttaactgtg cagcaatcgt
     4561 ttttaagatt gggtctacta gacccactcc cataaaagcg atcatacagg tagctgctac
     4621 aactagcgct gaacttttcc cctttgtttc ttcatttgtt tgttcttgta tatctatttg
     4681 attctccaat atttccatcc ctttctctct attagcatca tacatgattt attttacatg
     4741 taaatatgca catgtaaaac gtggaaactt tactgtgata taataaagaa aataagacga
     4801 gaggtaggat ttttatgaat actttagcct atatattatt atgcgtgctt ttatccaaac
     4861 cacgttctgg gtatgaattg aagcagctga tcacaatttt ttgggaagcc catcacagtc
     4921 agatctatac aacgcttgcc aagttagacc agcagggtta tgtgaccgtt ttggacaaag
     4981 acgagcactc tcaaaaaaag atctaccact tgactgatga aggacgtgct cttgtagagg
     5041 aatggatcaa agaggaaact cccgctccta cgcaaaaaga tgaatttcta gcaaaaatct
     5101 atgctttttc gacgctcgat aaaacaacag ctactggact gctattcact agagaacaac
     5161 agctgaacaa aatcatgcaa aaaaatcaaa aaaaattgaa tgacctctcg ctagacaaga
     5221 aacaagaatt tggacgttat gttgtgatcc agcgcagaat tatgctttgt cagcaggaac
     5281 tccaatggtg tcagcaagta agagaacaaa tgcagcagtt ttttgagtaa gggataaaca
     5341 gaacctttct agaaatatct attgaagagc aaattatctt caataaaaga gcaatacagt
     5401 tggaaaagaa aaagcgatcc gaacgacagg ccaaaaccta tcgttcggat cactattttt
     5461 ctagaactgc attcaagaga ctatgacaaa aagcatgcca aggccttttt tcaaataaca
     5521 gtgttccatc attcattact ttgaattgct tttagcacac ttcttgaaag cgggccaacg
     5581 atgatcaact gcaacggtaa agcggcaatc acattcattt tccaagcatt catataagca
     5641 gagaataatt gatcaggtat tccttgttcc atgatcacac cgaataaaga catacatgtc
     5701 accattccta aaaccatcaa gcatgaaata gttaagatca tttggacctt gctttctgga
     5761 tttactggta gtttaaaggc aatttttttc gccagcacac cgatgatgaa gacatccaaa
     5821 atgaaagcca ccacgaatcc aggcactaga ccaatcaaca aacttgataa atgaagatct
     5881 tgatgcagcc ataaattata cgcgctcatc cccaagacca tcaaaaaaca catcattgtt
     5941 gtaaaaatta ttccttcttt tttatttgta ggcaatctgt accactcctt taaatttgtc
     6001 acgaaaatca tcgtagcaca tttaaaaatt tctcgtaagt acttttttta ttttctgccc
     6061 ttttatttca taaacttcat cagccgtacg ctcgacaaag taagaatcat gagaagtaaa
     6121 caaaatcgtt cccggatata tttgcattag cttctctaaa gcttcgatcg ttgccatatc
     6181 aataaaatta gtcggttcat ctaacagcaa cacattactt ggcttagtaa aaagcaaagc
     6241 aatcgtcaga cgggtcgctt ctcccccact taatgtacat aacggtttcg tcaaagtttc
     6301 ctgagcaaac cctaagtgat tcagcaaact acggacaagc gattctgaaa actctgtttg
     6361 tctcatgaca aaacgaatga tggattcttc agatgtcatt tgataaccct tttgctgata
     6421 tacttgaaag cttactttcg gagagagaag gattccttct ccttgtttgc ggatatgttc
     6481 taataaggtt gtcttacctg aaccattttc accgacaatc gcgatttttt tacctaaaga
     6541 aaactgaaaa tcaccattta ccagtaatgt tctcccactt ctttccaatt ggacattttg
     6601 tcccatgatg ggatagcggc tgtggagttc aagagatttt ggtactggaa aacggatttg
     6661 tttcatctgc tgcggcttgg ttgtttctcc tattttttgg agtcttctct ctaatgtttt
     6721 cgcattcttt tggatggctt tttgtacact gtctttttgt ttagaggaag acaaccgatc
     6781 cggtctgatt tgttgctttt tctttttact ggacactttt tccaactttt ccgcttgttt
     6841 tttcttttct tggatcgatt tttccaatcg ttttttctct ttcatgatcg actctgcttc
     6901 tcgtagctga gtctttttct ccaattcctt ttgagtgaga taggcactat aattccccga
     6961 aaactctcgg atttctccgt cttttacttc ccagattttc gatgctagct catctagaaa
     7021 atagcgatca tgactaacaa aaaccagcgt accataataa taacgaagct cttcaatcag
     7081 tcgatcaata ctttttctat ctagatgggt tgttggctcg tctagaagca tcccttgttc
     7141 ataagaagaa agaagacgta tcaactcgat ctttcgttct tcccctccgc tccatttccg
     7201 ctctgaagtt tcttccagtc ttaactggaa atgactggct aattccaaat ttaggtcctt
     7261 tgcttcagcg agataggtta attgaggcag gtagttgaag gtgatctctg tttggatttt
     7321 cccatgatcg ggaaaaagtt caccggctat tagtttgagc aaagtcgatt taccgacacc
     7381 attttctcct atgatcccta tacgatcttg ctgatagaca cgaagagaat caatagatag
     7441 ttctagctgg ttgccaaagc tgacttgtag atttgttata tttactgcta aattttccat
     7501 atgttttaca ctcctatttc atgtaaaaca acaattatcg atactaaaaa agagcagaaa
     7561 aatctgtttg caaaaaaact gcatcacatc ttttcctact ctgaacgaaa taactatgac
     7621 taaatcacca aatctgtcat agctttcacc tattctactg tcgttcgaaa aaatggacat
     7681 actccatcca tgaaattgtt gtttatacat gtcttttgaa tttatttagt tgttattcaa
     7741 aagttcgaaa cgtaatttca tcgatgcagt catttttccg acctcctttt ttattaggtt
     7801 accacacacg attcaaaaaa agcaatagct actgaatagt aactgaaaac cttttattcg
     7861 aacgtagtga tcttttctgg tgctaaacga acagactcgt aaccttcttc taccgctttt
     7921 cctattgata aaataataac tggaacataa cggtctttat ccaaaccaaa tgcctctgcc
     7981 aactgatctg cttcgactcc accaattgga tttgtttcat agccatgatc acgcgcaact
     8041 aacatgaatt gcatagccgc taagctagaa tcgactttga ctacatcgtt catttcttct
     8101 cttgaaaaac tcttgtaata aggaatgatc gcagctaatt gttgatctct gacttctttt
     8161 ggcatcttcc ctgattcgta agcttggtta tagatttctt cgccatattc gtaacattgc
     8221 atatcgccaa aaatcatgac cattgcagaa gaagtatcat tttgtctcgt attgaaacgg
     8281 atcaaaggac gcaagatttc ttttgcttcc tcgctttcag cgaccacaaa gcgccatggt
     8341 tgcatattga cagaagaagg tgcagtcgtc gcttctttga tcatttccag catttcttcg
     8401 tgtgggattt tgtatgtttc atcatatacg cgaacggatc ttctaccagt cataattgtt
     8461 gaaaaatcat ttttttgttc cattattatt aacctctttc gtttctgttg ttatattgca
     8521 aagttgggta ttcaatttat ctaaaagtgt tagaaattgt ttcatttcta catcgctgaa
     8581 agccggggat agcacggaac ctgtatcttt atggtccatt tcacaatgct cgattttctt
     8641 ctgggctttt tctgttagcg ctacatacac ttcccggttg ttctgaggat ttctctgacg
     8701 cgaaacatag ccatttgctt ccaatacctt cagatgacga gtaactgctc cttgatcaat
     8761 ctgcaacttt tcttgcaaac tgctttgtag caatggattt tcttctttca gtctcatcat
     8821 gatctcgtat ctagtaagac ttataccgat attttcttca aagatctgga cgattttttg
     8881 atcggctaat ttgatttgat ataaaaggtg actaatctct tctaaagaca taatttcctc
     8941 ctttctaata attgactcgt caacgattga cttgtcaata atagaataaa aaaagaaaaa
     9001 agtcaaagaa tcagctgtgt aataaaaaaa acgctctcaa tagaaaagta tagagaaaag
     9061 aaattttttg tagaatgaac ggaaaaaatg ataaagaaag cacaacgcta aaaccaagat
     9121 tattgattct tatcaaacta tagaagatag ctcttctgca gtagaaaatt ttacaccgcc
     9181 aaaaatttcc gaaatcgcct tttgcaagaa tcccgtcgaa tattagaaat tggatcagta
     9241 tgcttaaaca gtaataaaaa agttatgaca agatgttgtc acaacctttt ttgagtaaac
     9301 ggtgttcaaa aacttgcatc tgcggtaata agttcaacca aacaaaaaac atgaaaatct
     9361 gtttttgttt ggctgttctt actacttgat gcagggcagc tttttcacta cctcttttta
     9421 ataaccataa aatcctattc cttcatatct ccagcccatc ggtgttagcc aatctctttc
     9481 cttagcactc aaggtatagt gatgggtacc agttttttca tttggattaa atagtcgata
     9541 aattggcttg gaaccaccag aataaaaact tagaccttca taacgccaac cgatttttgt
     9601 taaagagttg atctcagatt gtgccattgt gtaatgatgg tctccactgt aaggattgta
     9661 taaacggtag acaggttgtc cgctgtttgg tgcttgccaa gcaatccctt catattccca
     9721 gcctacagtt ggcagataat ttttttctcc ggcattcaat gtatataaat gttctcctgt
     9781 atgacggtta tacagacgat acatcggaga agttgaagtt ggtgctgtat catactgtgt
     9841 cagattatag gtttcgatta cattgttcaa tgtagaacca taattaggcg cagtggcata
     9901 acgacctgtt agccaagccg tagcatcttt gtaagagttc gtattgcttt tccatgcacc
     9961 ggaatagtag taaacgcctg gctgaaaaga agtcgtcttc aataccgtta cgttatcttg
    10021 caatgattct ttgtacgaag gatattttct aaaagcggca ttcaccgtaa tccattgccc
    10081 attcacatat tccgaagtag gcatcgtaac agattggcca ttatagcttc ctttaatccc
    10141 aaatagattg taattagggg cagaagccaa agtactgttc ccccagccac tttcaacgat
    10201 ggcttgagca atcatgactg atgcatataa gtcattggca cttgccaaac tttgtgcagt
    10261 tgaggcaata ctatcaatga acgcttgttg agaattagca gatgagcgag cataaaaagc
    10321 atagccagta tagttttcga attcagacaa atctgcttga tgggtatgtg tcaatgtttg
    10381 cccatctgtc aattggttcg tgatttcttc tgcattctct ggattgttct gagcttctgc
    10441 tgatgtactg tcttcggttt gtgtttgttc tgttgtttca gttgttggtt cttcggttga
    10501 aattgtattt tctgagacag tagctgactg caaagtactc tctgtatcgt tttcaattcc
    10561 tgtttctgaa gaactcgatg tctgagttgc gacagtttct gtcgattctt cagctagcac
    10621 tgttgtgttg gcaactgcta gatttcctaa aagaataacg ctaaataata aattctttgc
    10681 tttcatcttt tttctccttt gaattatgaa acttttccta aataacagtg taactaaaaa
    10741 agtaaaagca agtcaatgtc catatttaaa taacatttgt ttctttttga taaatttgct
    10801 ttttctacat aaaaagacgt aaatgaagaa tattcttctc cattcacgcc ttaaattgat
    10861 ggtcgtttga ataactattt aacaagtaat tctctttgga tattatccgt tatggattat
    10921 acttcctgtg tcgtcggacg gataatcatg ttactgacag acatccggtc tggcgtttct
    10981 atcgcaaatg ctacagcaga agctatatct tcggaggtca atccccattc tttttgcgct
    11041 tcatgaagtt caagagcagc ctttttgtcg ctgatggttt gatataattc agtttgaaca
    11101 gctcctggag agatgatcgt agatttgatg ttattttgcc gttgctcttg acgtaatcct
    11161 tccatgattg cacggacagc aaattttgtt ccgcaataaa cggcggaatc aggataaaca
    11221 acatgtcccg ccacagaatc agttgaaatg atatgcccag atttttgttt ttccatgatt
    11281 ggaagtacgg cggaaattcc atttaacaca cccatgatgt tgatatcaag catattttgc
    11341 cattcatcac ggtgaccttc aactaatgga gcggttggca tgattcctgc attattgtac
    11401 aatacatcga ttcgaccgaa cttttccatc gctaaatcga taactgcttg gacttgtgca
    11461 aaatctctta catctgctgt ttgaatatat agctcagctt ctggtaaaga ttcttttatt
    11521 gcttttaggc gatcttctcg gcgtgcagct ataactagtt tagccccttt ttctgctaat
    11581 agcttcgttg ttgcttcacc gattccgctt gaagcgccca tgatgacaat cactttttct
    11641 gataaatcat tcattctatt ctcctcctgt tttgaaaaat ctcttgctta tactcactat
    11701 ctcttatttc atcttactgt tcaaataatc cgttcgacag gtttgacgat tttggcaggg
    11761 attcctgcaa cgatggtatt gtctgggaca tctttcgtaa cagttgcatt cgctgcaaca
    11821 atggcattct cgccaatcgt tacgcctggc agaatagttg ctcctgctcc gatccaagca
    11881 tttttcttga tgtggattgg ctttactaac aagcctcttc gttcttttgg atcggttaga
    11941 tggttcaccg tgatgaggtt gacacgagga ccaatcaata ctgaatcttc taaacagatg
    12001 ccacctaagt caacgaacat cacttgacga ttgataaaga catttttccc tatactaata
    12061 tgtttgccga aatctgtata aaaaggcagc agaacagtca ccgtatcatc tactttgtca
    12121 ctaatgatat tttctagccg tttgcggata tctgctggtt catggtaccc agtattcagc
    12181 gctgctaaag gctcttcgtt ttcagcttgg atctgatgga tcacttcaaa gagcggatcc
    12241 gttactcgaa tctctttatt gacgatttgt ttttcgatga ggcttgtcat tttgctccct
    12301 ccttttatcc ttactttata acggacggct tatcatgtct aatacttata aaacatactt
    12361 aactattcct tttaactata cttagtggta tgctttttta aaaacaggag ggaaaaaatg
    12421 gatattcgta tactgacgta ttttttagca gtagctagag aaaaaaatat cagccgagca
    12481 gcaaaatctc tgcatatcac gcaacctact ctctcaaaac aactgaaaga tttagaagaa
    12541 gaacttggtg tgacactttt cactcggggc tcccgagaga tacagttgac ggattctggt
    12601 cgatatcttt attcaaaagg aaaagaaatc ttgtcgttgg tagaaaaaac ggcgaacaat
    12661 ttaacaaatg acgcaatcat ctctggagaa atctacattg gcggaggcga aactaaagca
    12721 atctctttca tttctgatag ccttcattcg ttgatcaagg cgcatcctga tatccagttt
    12781 catttatata gcgggaatgc agatgatatc atagacaaac tggatagcgg attacttgat
    12841 tttggactcg taatcgaacc gacaaacaaa caaaaatacc agtcatttcg actgccagcc
    12901 caagatcgtt ggggactttt gatacatcga aatcatcctt tagcaaagca aaccgtcatc
    12961 catccgcagg aactgaaaac tgttcctttg atcatttccc ggcaaacgtc agtggacagt
    13021 caactagctg aatggctagg tttcagcata gatcagttat cgatcgtcgg aacatataac
    13081 ttattgtaca atgcttcttt gatggtcgat aacgggactt ttggtgcatt agctctagat
    13141 gggatcatca atacttatgg gacggaaaaa atattcatcc cactcgatcc gccattacaa
    13201 gcttcactga atctcatttg gaaaaaagac cagcctcttt ctcctgctgc tcgtaaattt
    13261 ttagatgtcc taacggagaa atacagttaa gtagagtttt tttccttcgc tttcagcttt
    13321 ttaacaacga ataagataag caaaagatcc aacgattaaa taacataagt ttcttaattt
    13381 atttcttcct tttatttctg ataattccag taaattacta taattataaa aaaagaattg
    13441 acaaaacata actgtctata taaaattgat tacgttaaca ataattcgtt tcatgtgact
    13501 agatcatact aggcatgaaa aatctctgag gaacatggtt tccctaggag gtttttcgtg
    13561 tctatttttg tttggccgca atcaactggt ctagcaaacg tgaaaaccaa atcttcaaaa
    13621 agggtgcgcg catgaaaatc aaaaagatct ttaatcaaaa tgcagtattg gtagatgacg
    13681 gtggacagga aaaagtagct attggaaaag ggattggatt tgacagaaaa agaaatgatt
    13741 tgatttttga tcgtgatgtc gaacggatat ttgtcatgga accagaaggt caaatcaagt
    13801 tgcaaaattt acttaatcag attgatgaac gctttttatt tgcagcagaa acgatcattg
    13861 atcatgcgga aactgttttg atggaaaagt tgaatgaaca tgtattgatc gctttgaccg
    13921 accacattgc tttttctgcg gagaacatta ataacggtat cgtcatccgc aacaaacttt
    13981 taagagaaat cgaagtgctt tacagtgatg aattcagtat tgctcaatgg gcagtagagt
    14041 atctgacaaa agagcttggg attccatata cttatgacga agcaggatat atcgcaatcc
    14101 atattcacag cggacgaagc ggtcggaaca ataaccatcg cagtatccgt gaagtgacga
    14161 ttgtatctga catcatccat ttagtggaat cagaattgga aacagatatc cattcagaac
    14221 cattttcact gaattattca agactggtga atcatttacg actgcttcta caacgaaccc
    14281 atgcgcaaca atatgctgtt ttagacacgg aaatcgtaga aatggtcaaa cgaaaatacc
    14341 cagaaagcta taagatttct aaaaaaatcc gtgtgttgct gaccaaagaa taccagctcg
    14401 cgatcacgaa agaagaactg ggttacttgg ccatccatat cgagcgttta agaagcgcaa
    14461 tcgtacaaac aaatgttaac aatcatgagg aggaaaaaaa ttgaaagcat atctacaacg
    14521 aatgggacgt tcccttcaac ttccagttgc ggtcttacct gctgctgctt tactagtagg
    14581 gatcggaaac tggtgggcat cttatagtaa cgacattgtc gctcattttt tacaagctgg
    14641 cggtaacgca gttttaggtc aattaccttt gctgtttgcc gttgggttag cactagggat
    14701 gtcagtggac aaatcaggtg ctgctgcctt ggcaggtttg gtcgcatttg aagttccagt
    14761 aaatgtttta aaaactgatt cagtagctac tttattgaat atcaaaccag aatcagttga
    14821 tccatctttt gctcagatca gtaacgtatt tattggtatt attgccggat tgattgcggc
    14881 agctctttat aatcgtttcc acgaagcaaa attaccgatg gctttatctt tctttagcgg
    14941 caagcgtcta gtgccaatct tggctgcctt tgtcatgttg ctgatcagtg cagtgctact
    15001 gctcgtatgg cctccggttt actctgcttt agtttctttt gctaaattca ttttgagttt
    15061 aggctggggt ggtgcaggtc tttatggctt cttcaaccgt ttactgatcc ctacaggatt
    15121 gcatcaagca atgaactccg tgttctggtt tgacgtagca ggaatcaatg atattggtaa
    15181 atttttggct tctgaaggaa caaaaggcgt aacaggaatg tatcaagctg gatttttccc
    15241 aatcatgatg ttcgggcttc cagcaggagc atatgctatt tacagaaatg cacgtccaga
    15301 aaacaaagca aaaacagctt ccttgatgct agcagcagct tttgcttcat tctttactgg
    15361 tgtgacagaa ccacttgaat tttcatttat gttcgttgct tggccattat atgtcttgca
    15421 tgcaattttc actgggattt ctttagcagt gagtgcattc ttccattgga cagcaggatt
    15481 tgcctttagt gccggatttg tcgattactt cctatctttg aaaaatccga ttgcgaatca
    15541 gccattgatg ttgatcgtcc aaggattagt aacagcagtg atttactact ttggctttaa
    15601 ctttgctatc aaaaaattcc atctgatgac tcctggccgc gaggaagcag atctttcaga
    15661 tgacgatact gcaacgacta attcagacaa taaatatgcg gcacaagcaa gcaaaatcta
    15721 cgctgcatta ggcggagccg acaatgtaac ttcgatcgat aactgtacta cacgccttcg
    15781 tttgcaagtc aaagatacag gcctgatcga tcaaaataaa atcaaagcca ctggcgtacc
    15841 tggtatgaag atcatcgacg gaaaaaatgc gcaagtcatc gtaggtacag aagtacaatt
    15901 cgttgcagat gagatggcaa aactacatgg tggtgctgca gcacgacctg cacaaacaaa
    15961 caccgtggtt aaaacagaaa catttgccgg tgaaacgatc gaacaagata tttacgctat
    16021 cgcaaatggg aaactgattc caatcactga agtttcagat gatgtattcg cggaaaaaat
    16081 gatgggtgac ggctatgctg tattaccaga aaatggagaa atcttctctc caatcgctgg
    16141 tacgatcaca aacattttcc caacgaaaca tgctgtcgga atccaaacag atgctggtat
    16201 cgaagtcttg cttcatatgg gcatcaacac tgttgactta aaaggcgaac cattcacttt
    16261 atatgtagaa gaaggtcaaa aagtcgcaag aggtcaattg attgctttag ttgatcttgc
    16321 cgctattcaa tctgcaggca aaaacacgga tatggtcgtt gtattcacaa atggcgacaa
    16381 agtccaaagc ttagaaatcg aacccgcacg tgatgtaaaa gcaaatgata aaatcggctc
    16441 tgtttccaac aaagcctgag ccatcgtctt ccccagactt ttttatcgat aaacaaacag
    16501 gagctgagac aaaaatcttg tctcagctcc tttttccgaa taaaaacggc gttctcctgc
    16561 caactccgcg gtaataagtc cagctaaacg aaacatatga agagctattt tttatttgac
    16621 tcttcttatt acttgatgca gaacagcttt ttcacaaaat ttttcttcat actcaaaact
    16681 aatcggcttt ttcacaacct ctttatacat tattcctgat ccaatatttc ttttaatgct
    16741 gcttcaagag aagttaatgg ttttcccaat actttttcta aatcatcaga ggaaatagct
    16801 aactgatcct ttttaatatc atgttggatc gctaaaaaca tgtcagctgc ttcttgaggg
    16861 aatccggctt cttttagatt ttcgacaaac gctgcatcac ttgcttcaat aatttctaac
    16921 tctttacctg tcgcacgctc taatgccttg gctaattctt catagtcagt tagattgccg
    16981 gataattcta agatttctgg agagtcactt tctactagta cttttgctgc agcttctgca
    17041 tattcacgtt tcaatgccca acctgttttt ccatttcctg cagcataaac gaattgacca
    17101 gtttttaaag cctgcccaat gataggtaat tcattctcta cataccaatt attccgtaaa
    17161 aatgtatggg aaatacctga atccttaatc attttttcag tgaattggtg atctggcgct
    17221 aatacactga tcgagtgatc ggcatctgca aaacttgtat aagcgatata agatacccca
    17281 gctgcttgtg ctgccttcac tacattctta tgttcggctt gacgatttcc tggaacgcca
    17341 gagacaaaaa gcaatcgatc tattcctttc aacgcttctt tcattgagtc taaatcatca
    17401 taatcaccaa tacgtatatt aaatccagct tctttcagtg cttctccttt ttcttcacta
    17461 cgtactagta catagatttc attttgtgga accatctttt ttaagaattc cagcgcataa
    17521 ccaccaaaac ctccagttgc tcctgttact aaataatgca tatttgccac tccctattct
    17581 ttttatttgt taagatttac agctgtacat ttataaatta cacctttatc ataaagagtg
    17641 tggtaagata agtcaagcaa aaaaaatgaa aggatgacaa ctgatgaagt attctctgca
    17701 atttagtgat gcaatccatg tacttgccta tattgaaatg tttcaagata cccgatcact
    17761 ttctagtgag atgattgcca gtagtatcga aacaaatgca gcaaatgtac gtaaaatcat
    17821 gagtcagctc aaaaaatccg gtttgatctt tacaaaaacc ggaaaaccgc agccttccct
    17881 tgccaaaagt ccagatcaga tttctttact agatgtctat cgcagcatcg aaggtaatac
    17941 acagcttatc caagtcgatc caaaaacaaa tccaaattgc gtcgttggtg cgaatatcca
    18001 agaagcttta gaagaaagct acgctcggct gcagaaaaag gcagaagaag aaatggctaa
    18061 gatcacactt gatagtctga tacataaaat agccgttttg gaaaaagaaa aaagaccaga
    18121 aaacacaggc ctcgtagaga gatttttata attctctcta ctgtgcctgc atttttctga
    18181 tcggaatcgt ctacataaat tcttttattc tccgggggac aaaagccttg tcatgcccct
    18241 ttttcctctc taatgctcag gtcaaagcgc tgaagtcatg acgtcttgat aaacggtgtt
    18301 caagtagctg accctcggca ttagttctga aaaatgcaaa atatggaaag ctatttccca
    18361 tttttcctct ctaatgctca ggtcaaagcg ctactttcac gacctctata ttatcatggt
    18421 ttattgacta ccggtatcca gatttctccc atatatttcc cgttggtaac tcccatttcg
    18481 actacagcat ttggaccccc aacataggcg taatcttcta cttctcttaa aacatgccca
    18541 aaggccgtat tcgtcaaatc atttcttaat tcttcaggcg attctgctaa agcgcttaca
    18601 acaagatacg ttccttttgg gaatgggatg attcgcgtag tgtttggaac atcctgactc
    18661 gtttgaacac cgacatagta catcattttc ccgttatagg gttcgttgac tgtaaagaaa
    18721 taatgatttt cagcagcttg tttcaatgca tctattgttc cattaccgat aactttttgc
    18781 tcaaatgctt gtttctctgc agccaaaccg acaaaatccg tattgctact cttcaattcc
    18841 acaccaatac ccgtcaccgt aaaatctggt ttttcttcga tcctatactt tgccatttct
    18901 cccacccttt ctattatatt aagttcatct tacataaaat taaagggaaa tgacacgatt
    18961 acgctctttt ttctagggat atttttattt tttaactatt tttttgcttt cactgcaatc
    19021 caaatctcac tgtaaacatt actgaaatcc tctccccatt ttgtaaaaga gatctcggga
    19081 gcttcgacta acccataatc tgaagaagga agccattctg catagatttt cccccaagta
    19141 tcttgtaaag tttggggaaa tggcccttta ttaggaaaaa tggcccaagt gtgttcttct
    19201 atagcaagca tttctaaatc agcgtacgga ttttcttttg tcgtagcaaa gccaatcatg
    19261 tgcatcaaac tgcccttttc ttccaagcgg tctccatcaa atccataaga aacgttgatt
    19321 acttgatttg gatataaatc tcctaactta tgcatctctt ccctttgagt ctccgtgatc
    19381 gtctgcgcta acttttgtat ttcttgattg actccttcaa atttgacagg aacttttttc
    19441 gccacacctg ccacataaaa ctgttctttc ttttcgatac gaaattccat cgattttcct
    19501 cctctgacat caataaaaaa tgtcaagcgt ggaaaagatt tttgtatgcc gtatctgctg
    19561 atttctgaag gcagatatcc tgaccaatca cgaaaagctc ttgaaaaacc ttcgactgtt
    19621 tcatatccat atctaaacgc cgtttctgtc actcttgatc catctagaag atcgcgatta
    19681 gccaaagcca atctacggtt tttgatatag tccattagcg acatccctgc aataaacgta
    19741 aagatgcgtt ttaattgata ttcagagatt cctgtatttt cggctattat tttataggaa
    19801 agtccttctg tcaaatgttc ttcgatgtaa tcgatcaatt ggttcagatc tttaagcata
    19861 tttatcttcc tccttgattg cctttttatc atattatcaa agaaagtcaa ttacttgatg
    19921 aatcaggaac caatttagtc agatgtagaa aatgttgtat ggatctaaag aaaattctca
    19981 agcagcgttt cgtaacggat aattggtatt atctgcctat ctatgtttta cctttagaaa
    20041 aataaatttt ggggaagaca gattctaagt aaacaaagcg gtaaaaatat cttttattcc
    20101 cttagttaat ccgcttacta cctactgtac aaagcaaatt gttgttcaaa ctgctgatca
    20161 gaacgctgct tggatttttc ttt
//
LOCUS       DAYYEF010000049        19507 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000049 DAYYEF010000000
VERSION     DAYYEF010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.051"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="ACHA1B_002065"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="ACHA1B_002065"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HFM8702814.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="ACHA1B_002066"
     CDS             complement(1173..1868)
                     /locus_tag="ACHA1B_002066"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HFM8702815.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="ACHA1B_002067"
     CDS             complement(1881..2597)
                     /locus_tag="ACHA1B_002067"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_function: GO:0140098 - catalytic activity, acting on
                     RNA [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HFM8702816.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="ACHA1B_002068"
     CDS             2927..3532
                     /locus_tag="ACHA1B_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_function: GO:0008097 - 5S rRNA binding [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HFM8702817.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="ACHA1B_002069"
     CDS             3857..4180
                     /locus_tag="ACHA1B_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HFM8702818.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="ACHA1B_002070"
     CDS             4362..5732
                     /locus_tag="ACHA1B_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HFM8702819.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="ACHA1B_002071"
     CDS             complement(5862..7163)
                     /locus_tag="ACHA1B_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin family protein"
                     /protein_id="HFM8702820.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9384)
                     /locus_tag="ACHA1B_002072"
     CDS             complement(7393..9384)
                     /locus_tag="ACHA1B_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HFM8702821.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="ACHA1B_002073"
     CDS             complement(9528..9794)
                     /locus_tag="ACHA1B_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFM8702822.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="ACHA1B_002074"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="ACHA1B_002074"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004654 - polyribonucleotide
                     nucleotidyltransferase activity [Evidence IEA];
                     GO_process: GO:0006402 - mRNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HFM8702823.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="ACHA1B_002075"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="ACHA1B_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HFM8702824.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /gene="def"
                     /locus_tag="ACHA1B_002076"
     CDS             13138..13701
                     /gene="def"
                     /locus_tag="ACHA1B_002076"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042586 - peptide deformylase activity
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HFM8702825.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="ACHA1B_002077"
     CDS             complement(13954..14475)
                     /locus_tag="ACHA1B_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HFM8702826.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="ACHA1B_002078"
     CDS             complement(14478..15320)
                     /locus_tag="ACHA1B_002078"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HFM8702827.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="ACHA1B_002079"
     CDS             complement(15313..16038)
                     /locus_tag="ACHA1B_002079"
                     /EC_number="2.3.1.286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_function: GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HFM8702828.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="ACHA1B_002080"
     CDS             16214..16510
                     /locus_tag="ACHA1B_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702829.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     regulatory      16766..16940
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00168"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Lysine riboswitch is most abundant in Firmicutes
                     and Gammaproteobacteria where they are found upstream of a
                     number of genes involved in lysine biosynthesis, transport
                     and catabolism; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="lysine"
                     /db_xref="RFAM:RF00168"
     gene            17078..18670
                     /locus_tag="ACHA1B_002081"
     CDS             17078..18670
                     /locus_tag="ACHA1B_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFM8702830.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="ACHA1B_002082"
     CDS             18683..19423
                     /locus_tag="ACHA1B_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HFM8702831.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGSEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5581 a         4002 c         3701 g         6223 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggca gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaa
//
LOCUS       DAYYEF010000050        18805 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000050 DAYYEF010000000
VERSION     DAYYEF010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18805
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.052"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            44..1411
                     /gene="nhaC"
                     /locus_tag="ACHA1B_002083"
     CDS             44..1411
                     /gene="nhaC"
                     /locus_tag="ACHA1B_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015297 - antiporter activity [Evidence
                     IEA];
                     GO_function: GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA];
                     GO_process: GO:0006814 - sodium ion transport [Evidence
                     IEA];
                     GO_process: GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HFM8702832.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(1692..2711)
                     /locus_tag="ACHA1B_002084"
     CDS             complement(1692..2711)
                     /locus_tag="ACHA1B_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8702833.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(2733..3740)
                     /locus_tag="ACHA1B_002085"
     CDS             complement(2733..3740)
                     /locus_tag="ACHA1B_002085"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA];
                     GO_function: GO:0030246 - carbohydrate binding [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase family protein"
                     /protein_id="HFM8702834.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(3733..4398)
                     /gene="pgmB"
                     /locus_tag="ACHA1B_002086"
     CDS             complement(3733..4398)
                     /gene="pgmB"
                     /locus_tag="ACHA1B_002086"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0008801 - beta-phosphoglucomutase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HFM8702835.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(4391..6685)
                     /locus_tag="ACHA1B_002087"
     CDS             complement(4391..6685)
                     /locus_tag="ACHA1B_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HFM8702836.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            6945..9110
                     /locus_tag="ACHA1B_002088"
     CDS             6945..9110
                     /locus_tag="ACHA1B_002088"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIBC"
                     /protein_id="HFM8702837.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            9414..10247
                     /locus_tag="ACHA1B_002089"
     CDS             9414..10247
                     /locus_tag="ACHA1B_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HFM8702838.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(10349..12049)
                     /locus_tag="ACHA1B_002090"
     CDS             complement(10349..12049)
                     /locus_tag="ACHA1B_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702839.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            12556..13716
                     /locus_tag="ACHA1B_002091"
     CDS             12556..13716
                     /locus_tag="ACHA1B_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HFM8702840.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            13732..14175
                     /locus_tag="ACHA1B_002092"
     CDS             13732..14175
                     /locus_tag="ACHA1B_002092"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8702841.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(14658..15188)
                     /locus_tag="ACHA1B_002093"
     CDS             complement(14658..15188)
                     /locus_tag="ACHA1B_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HFM8702842.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            15293..15844
                     /locus_tag="ACHA1B_002094"
     CDS             15293..15844
                     /locus_tag="ACHA1B_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFM8702843.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(15997..16470)
                     /locus_tag="ACHA1B_002095"
     CDS             complement(15997..16470)
                     /locus_tag="ACHA1B_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HFM8702844.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            16608..18080
                     /locus_tag="ACHA1B_002096"
     CDS             16608..18080
                     /locus_tag="ACHA1B_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFM8702845.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            18077..18787
                     /locus_tag="ACHA1B_002097"
     CDS             18077..18787
                     /locus_tag="ACHA1B_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HFM8702846.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
BASE COUNT         5760 a         3398 c         3884 g         5763 t
ORIGIN      
        1 tttttcatgg cagggccttt tcatttgaaa taggagatcg acgatgaata aaaatatttc
       61 tttaaaagaa agtatcgctg tattgatcgt gttgttggca ctcctaggag tactgatcat
      121 cggattccag ctctcgccac atatcccgat ccttgcagct ttcatgtgtt tgttgtttta
      181 tggcagattt aaaaagttca catgggatga gatccatgac gggatcatca aaggaatcac
      241 tccagggatc attccaatcc tgatttttct tttgattggt gtcttagttg cttcatggat
      301 tttatctgga accatcccta cgattatggt ttatggattt aaacttgttt ctgtgcgttt
      361 ctttttaccg acagcatttc ttgtttgtgc aattgtcgga gtgactgtcg gcagttcatt
      421 tacaacgatt tcgacgattg gaattgcttt tttggggatc ggtcatttac ttggattcaa
      481 tgatgcaatg actacaggcg cagtcgtttc cggtgccttt ttagggaata actgctcgcc
      541 tttatcagat acgaccaact tggcagcggg tattggagga gttaatctat tcgaacatat
      601 cgctggtatg cgttatacgg atttcccagc attcgtcctt tcgttgattt tttatacgat
      661 attaggacat aacagtcatt cagccgatct agctagtatc aatgaaatga tccaaaacat
      721 gaaagcgagc ttttggatct ctccttggac attgattcca ctagttattt tatttggggg
      781 ggcaatcaaa aaaattccgg ctatccctac attactagcg ggatcgacag ctgctctcgt
      841 tctttctttt atccatgaga aaagtttgac ggtcggaaaa gcagcagaca tcttgatgaa
      901 tggttatgtc gcaaatacac ctgatccaaa gctagatgaa ctgctttctc gaggcgggat
      961 catgagtatg ttaggttctg ctagtttgat tttacttgca ttggcattag gtgggttact
     1021 gatcaaatat ctgatcgttg ataccatcgt tcaagaatta aaagaaaaga tggaccgacc
     1081 ttctcgttta gtcgggttta ctgccttgag ctgtatcgga atcaatctga tcgttggaga
     1141 acagtatctg tccatcattc ttccaggaga aacattcaag cgttcttttg atgacgttgg
     1201 cttatcaaaa acctatttga cacgaacact agcggattca ggtgcgaccg tcaattctct
     1261 cgtaccgtgg ggagtcagcg gcacattcat tatgggaacg atgaaagtta gcgcgttgca
     1321 ttacttgcca ttcgcctttt tctcgattct tgcacctgtc tttacaatat taggcggttt
     1381 tttattgaat cgtcgacgtg taaaaaattg aaggaaggaa aaaagaggct gggacagaag
     1441 cgtttaactc caagaaataa gaagaaactc aagaaaattg ctttttaaat ttttgtgaat
     1501 ttcagcttat ttccgaagga gttgcttctg cttccgccgt ttatacgtgt ttagagcgtg
     1561 agacaaaagt gttctttact tttgtcccac gctctttttt acagataaac aatgtgttag
     1621 aagtagtatc ttcttttaca taaaaagctg accataggat aaatggtcag cgtatttagt
     1681 gagtcagcta tttagtatgg gttttctaaa ggaacgactg tctctctttt gatcaagcga
     1741 tgagggatga ccaaacgtac gccactgctc aattcttcat ggatcaattc gcgcagcttt
     1801 tgcatagcga cacgtcctaa ttcggagata tcgatatcga tacttgtaag gtaagggtgt
     1861 gttaatgttg agaagatcga gttgttgaag ctaatgacgg agagtgtctc tggaatgaca
     1921 tagccataca tttgcgccaa ctgcatcgtg cgaagggcga agatatcgtc aatgaccacc
     1981 aatgctgtgg cttcgttttc tttcaacgtt ttctcaaagg acagataatc ctccggatgc
     2041 tctagtacta cactggataa cgcaggaaga ccagccatca tcattgcttt ttgataaccg
     2101 aaatatcgtt cgaaatacaa actttcatga gtcgtgtttg tcacaaacag gatattctta
     2161 tgtccattct ggatcaaaaa ttctgttgct tgtttaccta gaagctggtt atcattatct
     2221 acataaacga tttcgttctc atgatgataa ggctgtccga tcaaagtgaa agggatgtgg
     2281 ttttggtata aataatcaat gacagtatct tgactatctg aatacactag aataaaacca
     2341 tctacttgtt tttgtaaatg catacgctgg acgttctcta acagcaattc aaaattttta
     2401 gcagtagcga ttgctgtagt catatcataa ttccgcgctt cttcgttgat tgcttccatg
     2461 atctcaagat aaaatgggtt accgatccgc tcttttgaat caagaggggg taagattacg
     2521 ccgatggcac tggaaatgcg ttttcctaga ttgcgggcag tcatgttagg aacataacct
     2581 agttcatcca taatttttcg gactttcttc tttgttgtct cggaaatact aggatgatcg
     2641 ttgatgacac gagagacggt cgaggtggca acaccggctt ttttcgccac atcttttacg
     2701 gtaatagcca tgataaaaac acctttctct tgttattgtg cagagaaccg ataaatcgtc
     2761 tgactgatcc gttcttgacc aggatggagg ttgatcgatc caaatttggg gaaatgaacg
     2821 atatcaggga tttcttgcgg ttcgattgct aatccgtagt ttgaatgcat ctgttttcca
     2881 ttgacagaga aatcagcttc gaatccagtc gtagaaaata ataccatact tttattagaa
     2941 gttgctatag tcatttggcg accagaatgc ttctcgaata attgtaagga agttttggaa
     3001 agcctaggat gatgcaaaag aaatacatca tctagtccat ctggataaca tgcaaggatc
     3061 tcttgcagtg ttggggattt tctaaagtcg attggcagtt tttctttttt tgtccaattt
     3121 ccagtaggca gtttttcttg atctaattca agcacaccat ctaaaaagac cgttaactga
     3181 tgttcataga tgtctcttgt tccatttcct gaaaggttga agtaggcatg gttggtcgga
     3241 ttgcagatgg tttcaacaag gctactagca gaggttgtca tctctaattc gttttttgtt
     3301 aaacggtaag tgatcgtagc agtgattggt cctggatagg tagaaaattc atcttttaag
     3361 taaaagacca cacctattga tgatggagtt ttgaaaactt ctacttccca aaattggaaa
     3421 gaccagcctt tcgtgccacc gtggatatgg tgtgatccgc agtttttctc caatctatgc
     3481 tcaccccaag aagcatcccg gatccttccg gctacaggtc cgacagttgc tccaaaaaag
     3541 cttttgtctg ttagaacatc ttcgaaacga tcgtaagaca ataaaacatt ttctgatttt
     3601 ccttctttgt ctggtgcgaa gatttggtgc aggcgggcac cgtaattgag aagaacgact
     3661 tctaagtagt cgttcttcaa tgtgattttc tttatttcag tctctggaac tggtacgacg
     3721 gagatctctg gattatccat ggtcatgcca cttttctttc aagtaatcga tcgtaagaaa
     3781 agtcgtatca gggacaagcg ggatctcctc tccaaggtct tcagcacgtc ccacgccaat
     3841 tggttgagcg ccacttgaga ggatggcttg gataccggct tgcgcgtctt cgatcccgat
     3901 acattcttct gcttttagtc cgacagcttt tgctgcaagg aggaagatat ctggcgcagg
     3961 ttttccgttt gttgcttctg ccgggtcggc aatagcatca aagtaaggtg taagacccat
     4021 tttttcaagt aggaatggcc cgtttttact tgcagaagca agagcaatct tgattttttc
     4081 ttcttttaaa gaatccagta aaggcacgac cccggggaag acatcttttg gttcgatcgt
     4141 ctggatcatc tctaaataat aatcgttttt tcttttcgct aattctgcaa attcttcctt
     4201 tgaaaaagag tgttcttttc cgccataagc taaaagcaaa gagagtgagt cttctcggct
     4261 gacgcctttt agctgttcgt tgaatgtgtg gtcgatcgta atgccgattt cctgaccaag
     4321 ctttcgccaa gcacgataat ggaattcagc agtatcggta atgacaccgt ctaaatcaaa
     4381 caatacccct ttaaacattt gcttcctcct ttcttagcgt tatttctaga cgatccgcta
     4441 aagaataaga ctgttcatag acgtaaattt ctagaggaga accttctaat aactcgaaag
     4501 taacttgttc atctgtgact gagatgaaca ataaacgtcc gcgataattg atatggaaag
     4561 aataagcttt ccaagttttt ggcagaaatg gtgcgaatct caactgatca tgggcagttt
     4621 tcatttgagc aaatccttgg acaatcgaca accagctacc agtcatggaa gtgatgtgca
     4681 agccgtcttc tgtgtcgtta ttgtaattat ccaaatccaa gcgagctgtt cgctggtaca
     4741 tttctacagc tttgctttcc attcctaatt ctgctgctaa aatcgaatgg atacttggcg
     4801 aaagggaaga ctcatggaca gtcattggtt catagaaatc aaagtttttt tgcttttctt
     4861 cttttgtaaa agtatcattg aagaaataaa tcccctgtag tacatctgcc tgcttgatga
     4921 agcaagatct aaggattttg tcccaagacc aatgctgatt cagaggaaga tcgcttgtgg
     4981 gaatatcgga tacaggcatg agatctttat ctaagaatgt gtcatgctgg acaaagattc
     5041 ctaattcttc gtcaactggg aagtacatgt tctctgcgat atctttccat ttggctagtt
     5101 cttcttcgct gatagtgata gcagcttctt tttgataagt taaataattt tctcgcgtgt
     5161 aacgcaagac ccaagctgcg atcgtatttg tataccaatt gttattgata ttgttctcat
     5221 attcgtttgg gccggtcaca ccgtggatca tgtatttatt tgctcgtttt gaaaaatgga
     5281 cacggtctgc ccagaagcgt gcgatttctg ctaaaacttc cagtccttca tttttcaaat
     5341 attccgtatc gccggtgtaa ttcgtataat tgtagattgc ataggcaatc gcgccatttc
     5401 ggtgaatctc ctcgaatgtg atttcccact cgttatggca ttcgacacca gtgaaggtga
     5461 ccataggata aagcgcgcct tttaatcctt gttgctgagc gttgtggatt gcttgcggca
     5521 gttgattatg ccgatatttc agcagattct tagttacttc aggtttggct aaagcaagat
     5581 aaagagggac agcatacgct tctgtatccc agtaagtggc tccgccgtat ttttctcctg
     5641 tgaatccttt ggggccgata ttcaatcgtt catcttcgcc gtagtaagta gagaatagtt
     5701 ggaacaaatt gaatcgaata ccttgttgtg cttcttcgtc tccttcgatg accacatcgg
     5761 caagcttcca tcgttctgcc caagccgctg tttgctcttc ttttgcttgg atataattgt
     5821 ttgtctggtt cgttaattct gagacagctt tttctgcttg ctgcgcttct ggaatatctc
     5881 tactagtaag aacgataatt tctttttcca ctgaccatgt ctcaccttga gataattctg
     5941 cagacaagca accatgtaat gctaaagtat cttcgtgata gtcagggatg actgattttc
     6001 cattaacgaa atggcgcatt gctgcagtaa cagtaaattg ttcaatccca aagttgtttg
     6061 gaatagtttt agtcgtcaaa tagccgattt cttctatagt tccacgatca atctcattcc
     6121 aaaaatgttc atcatagttg ctgtcttcgt tttgaacatt tccatccaat tttgatacga
     6181 gtttgactgt tccgctacct tcaagcattt ctatagttaa atagatataa gctgattctt
     6241 ttttgacaat gctcagaaaa cgttcgaagg aaatgcgtac tttattagta gaagtagtga
     6301 ttgtgaatgt acgagataat acaccatttt tcatatctaa ttcccagtaa aagtcttctg
     6361 gttccaaaga agccaagtcg atcagctgat cgttgatcga aatatctatc gcgataaagt
     6421 tcaaggcgtt gatcactttt ccaaagtatt ctggataacc atttttccac cagccgacac
     6481 gtgtcttatc gggataccag acacccgcca aataagtacc ttgatggtgg tcccctgagt
     6541 aagtttcttc aaagttcccg cgcatcccca tataaccgtt tccaatactt gttaaagatt
     6601 cttgcagtcg aagatttttt ttatctaatt gtgtcgtgct gattttccat ggatcaatag
     6661 caaatagtcg tttgatctgt ttcatttttc tcctcctaat gagctgtttt atacgttcat
     6721 aataaacgca accgattgca caagtcaata gacaaaagaa aatatttcat agaaaaaagc
     6781 ttaaaaaaat aaatttttag gagaaaatta tagaagggaa cacacgtatt ataggtttta
     6841 tagaatggta tagacagaaa aataaaaaat aaagcattta caaaaaagaa aacgcacgct
     6901 ataatacgtt taacgaaacc gattgcgtaa aggagctaaa cggaatgaaa aagatattta
     6961 gttttgagtt ttggcaaaaa tttggaaagg ctttaatggt tgtggtagca gttatgccgg
     7021 cagctgggtt gatgatcagt atagggaaat caattccctt gatcaatcct gattggacgc
     7081 cgcttgtcac aacgggcgga gtaattgaaa atattggttg ggcaattatt ggtaatcttc
     7141 atattttatt tgctttagca ataggaggaa gttgggcaaa agaaagagca ggcggagcat
     7201 ttgcagctgg gatctcattt attttaatca atcggatcac tggggctatc tttggtgtca
     7261 caagtgacat gcttgcgaat gaagatgcat ttacccacac tctgttcggt acgaagatca
     7321 tggttaaagg attttttaca agtgtattgg aagcaccagc tttgaatatg ggagtattcg
     7381 tagggatcat cgctggattt gtcggggcaa tggcttataa taagtactat aattatagaa
     7441 aattgccgga tgctttgtca tttttcaatg gaaagcgctt tgttccgttt gttgttatct
     7501 tatggtcaac aatcgtggca ttgattcttg ctgtggtgtg gccaaacgta caggctggaa
     7561 tcaataattt tggtttatgg attgcagaat cacaagaaag cgcaccgatt ctagcaccgt
     7621 ttttatttgg aacattagaa cgtttactat tgccatttgg attgcatcat atgctgacga
     7681 ttcctatcaa ctatacacag cttggcggat cgtatgagat tttatcaggc gcacaggcgg
     7741 ggacacaagt atttgggcaa gatccgttat ggttggcttg ggccactgat ttagtgaatc
     7801 ttaaaggtgc aggggatatg tcgcaatatg agtttgtgtt gcataactgg acgccggctc
     7861 gtttcaaagt aggacaaatg attggttctt caggtatctt gatgggaatg gcttttgcga
     7921 tgtatcgtaa tgtcgatcct gataagaaag caagatataa atcaatgtat ttttcagcag
     7981 cgttggctgt ctttctaaca ggtgtaacag aaccattgga gttcatgttt atgtttgctg
     8041 ctgtgccatt atatgtcatt tattcagtga tccaaggggc tgcatttgcg atggcagata
     8101 tcttgccatt gcgggtccat tcatttggga atatcgaatt gctgactcgg acaccgttag
     8161 ctatcaaagc gggtctaggt ggagatctta tcaacttcgt gttgtgtgtg atcgcttttg
     8221 gtgttgttac gtatttctta gcaaatttct tgatcaaaaa attcaacttt gctacaccgg
     8281 gacgtaacgg aaattacgac aatgacagtg aagaaaccgt tgtatctaac agcggaacag
     8341 gaacagcaga tcagcaagtg gtccagatca ttcatttgct gggaggaaaa gaaaatatca
     8401 aagatgtcga tgcttgtatg actcggttac gcgtaagtgt aaatgatcga gaaaaagtag
     8461 ggactgaaga agcctggaaa cgagcagggg cgatgggatt gatcgtcaaa gacaatggag
     8521 tccaagcagt ttatggacca aaagcagatg tcttgaaatc agatatcgaa gatctgctgc
     8581 aatcaggagc agagattcca gagccagaaa tggtttctac aggaaatgga caagcaggta
     8641 gtaagcaata cttaggtata gaacaagaac tagtttccgc agcttctgga gaagtgattc
     8701 ctttatctga agtaaaagat ccggtattct cacaaaaaat gatgggtgac ggctttgctg
     8761 ttattccaac atcaagagaa gttgttgcgc cgatcgctgg aaaagtgaca agtattttcc
     8821 ctagcaaaca tgcaattggg ctggaaacga aagatggtat cgaagttttg atccatatgg
     8881 gaatcgatac agtccaaatg aatcagccag cttttgagat tgctgtcaaa gaaggccaag
     8941 aagtaggaac aggaacgaaa ttagctgaga tggatcttga tgtgatccaa aacgaagaaa
     9001 aagatccaac gatcatgatc gtatttacaa acgataaagt agaagaagta gtgatcaagc
     9061 aattaggtac agtgacagct ggtaaagtga tcggctccat taaaatgtaa ggagaggttg
     9121 tgaaaaagct gtcctgcatc aagtcataag aacagccaaa caaaaatagc tcctcctatt
     9181 tttcgtttgg ttgggcttat taccgagaag cagcagtttg aatactgttt agtggagagg
     9241 tcgtgaaaaa gctgccctgc accaagtgat aaaaacagcc aaacaaaaaa tagctcctgg
     9301 tccattgagc ttattactga ggagttagca ggagaacact atttgctgga gaggttgtga
     9361 caaaaatttt gtcacaaccc ttttgtttcg aaatgaagac aaggagaaaa ccaatgaaat
     9421 tcatgacact caacacgcat agctggcttg agccagaacc agagaaaaaa ttgcaagaat
     9481 tagcagataa gatcctgtta gaagattatg aagtgattgc tttacaagaa atcaaccaat
     9541 tactggaatc tgaagaagta gaacctgcga agctaatgaa gttctgtccg gtaaagaatc
     9601 aagtacctat ccgtaaagat aattttgcct accgtttagt tcagctttta aaggaacacg
     9661 gaaaagagta tttttggagt tgggaaatga gccacatcgg ttatgataaa tatgaagaag
     9721 gaaatgcact gcttacgaaa aaaacattgg aaagtcaggt ccttaccgtc tcccaatttc
     9781 aaaagaaaga agattatcag acacgcaaga tcttgattgg gaaaacaaag atagatgatc
     9841 aggacatttt tgtctcgagc tgccactttt cttggtggac agataaaaaa agtggctttt
     9901 attttgagtg gaaaaacttg gaaaactact ttttggaaac tcgcgtacca ctttttttcc
     9961 taggtgattt caataatcca gtagactctc aaggttatta tactgtaaga gaaagttgcc
    10021 ttcttcttca agattcgtat gttgtcgcga atgaaaaagg aaaagcagct actgtggaaa
    10081 agaaaataga tggttgggaa caaaatacag aaaaattgcg tatagatttt attttcgtcc
    10141 ctgaaggaat gcaggttaaa aaatatcaac ggatttttga tgggatcgat agtccaatca
    10201 tcagtgatca ctacggggtg gaaatcgaat tagatgtgaa cgaataaaaa atataacata
    10261 taacataaaa aaactgatta aaataaaact ctccaaacga ttataccgtt tggagagttt
    10321 tttgatcgga tgtatttatc ccttttgcct aagcacgtaa aagcttgtat ctatgataaa
    10381 taaataaaca tagcaaggta aaccagccaa tcaaagtaag agaaagaatg aaatagaaat
    10441 agattggcgt ttgataatga agcgtgagct cgttgattcc tttttgctgc ttcacgattg
    10501 gggtcccgat atctgttact tcataatcag tcaatgtttt tccattttgc tgtagcacag
    10561 tccgatcgta gacgataaca gggatatgaa cagttttgtc cccagtgttt ttccacttga
    10621 ttgtcaaaag accgcctgga tgtgttttta taaaagttgt ttcgttttct agtatttctt
    10681 cgttataccg gtcgtattta ttgtcttttg tctccttata gattggcaga tagtcaggtg
    10741 tggttttttg gaaaacgaac aagctggtag acatatcttt gctgaagaat gttttccttg
    10801 cttcttccgg cgtatcgaat agataagtat gtcgactgac aaatgtttca ttttcccact
    10861 tttccagatg ctggtataag ttctggatcg tctgtgctga aaaaataaga atgccaaata
    10921 tacttaaaag acggaaccac ttttgttcag accactggtt cagtgaaagg gcaaggtaaa
    10981 gtagaagcaa tagcgtaaat ggcacgaaaa atcgaaatgg aaactggatc aaactaataa
    11041 aaggcacatt tttttcgatc aatgtcgtcc atggaatcaa gctagtagaa agaaaaaaga
    11101 aaacaagact tgtgtacaac acgatttttt ggaataaggt gttcttttgt tgaaagaaaa
    11161 taaaaagcaa aaaacctgat aatatcaata taggaaaggc cttagggtaa tggagccaat
    11221 aactgccatc cagatctatc gccttttgac tcatttctct gttaacaaag ggaggaagaa
    11281 tcttattccc actgtaaaca atagctaatc ctgcccaaat atttgctgtc agaacaaaat
    11341 aaagcaagac cgacttaatc agttgaagca gtgcttttcc tttttcagtc tggttaaaaa
    11401 agtaataaag ataaaaaggg atatacatca aagctaacat gatcgaagac agtaaatgga
    11461 tctgtgtcat aagtcccact gagacagcga ctttgataac agggaacttt ttatgaagga
    11521 cgaaatcagc aatagggatc atacataaag gataaaaaca agtcccccag ctagtgaatc
    11581 cttggttgat agaccagtat tgaatagaat acgtactcat gaataaaacg gctactggta
    11641 cacttaccca atttcgaaca ttgacatatc tcagtaaaat cagcatagaa aatcctgaaa
    11701 taagataaag aatgaaattt gaaagaatct gataatgaaa ccagctacct gcaagcaaca
    11761 cgatcaatcc ttgtaaataa gcgaaaaatg ggccgtaaac ggcattcacg atcctgccac
    11821 tttgttggaa tccataaagg gaaggaaaat aatggaaatc cccatattta atttgttgcg
    11881 cggcatcata gaaccgattg taatggaatg gggcatcagc acccaaaatt agtttatgtg
    11941 tgaataaatg aggcatgaga aatgccaaag caatgaaaaa aattgctaaa aatgggccat
    12001 attttttcaa ttgtcgaact cctttgcaaa ctttagataa attcatcata tatcctatgc
    12061 gagaggtagg caagaaatta gaaaattcat gaaaatattt atgaatttta caagaaaaac
    12121 ataagtgaaa gttctaagga gagaggatgc gacataagtt ttgttgcatc tccttgtttt
    12181 gaaacagaat ttttcttaat actcgaaaca aagtagcttt ttcatgacct ctcggtaaac
    12241 ggtgttcaat cagctgcttc tcggtaataa gctcactagc ctagaaaata tgagaagcta
    12301 ttttctgact agcgctctta ttactcaaag cataacgcag ttttcacaac ctcttcctta
    12361 aacggtgttc aaaagcttgc atctgcggta ataagcccaa cccaacaaaa aatatgagta
    12421 gctatttttt tgggctgtac ttattacttg atgcaggaca gctttttcac aacctcatcg
    12481 gctttcattt tctatttttt tcctgaaccc atataataaa agaaagaaca aaaaaacttg
    12541 caagggagga cacatgtgaa gcagagtaag caaaaacagt ctcgtcgact tttgtttcgt
    12601 ttgtttttat taatatgtat cgtcgtaggg ttactgatcg ctttatatcc attttatgtg
    12661 gattctttaa atagttttat tgatcaaaaa cgtatcgaac aagtacaaaa acggaccgca
    12721 gctgaaattg aagtgcagcg aaagaaaatg gaggagaaaa accaacgatt aactgaccaa
    12781 ggattcaatc ctggtactga tcctttcaat gaaaagaaca gaaatgaaag tacaacatcc
    12841 agccaattag aggaatggct gatcggaagt atcaatatac ctaagatcca attaaatatt
    12901 tcactttatg atcggctcaa tggtaggatc cttgaaaatg gagcaggcgt cttgcaagga
    12961 acctctttcc cgcttggtgg aaattcgacg cattcagtga tctctgctca cagcggttta
    13021 cctaatcgac ggttatttac cgaattagat cgtttagaaa acggagacac gtttattttg
    13081 actgttttgg gggagaaatt ggcttatcaa gttaaaaata tacaagtggt actgccagat
    13141 gacacgtctg ttctaacgat ttcagaagga gaagacttag ttaccttgct tacatgtacg
    13201 ccgtatatga tcaacacgca tcgtttgcta gtgacaggac atcggattcc ttataacgaa
    13261 tcggtaaaaa aagaagaagg aaaaggaaat caggaaagaa ccatgcggca atggtttatt
    13321 cttgcaggaa cgataatagc tgtagtcata ctgttagtgt ttatcggacg actaatctat
    13381 cagtatagat taagtaaaaa agtgcttgat ttttcattta ttattagtga ttcgtcaggg
    13441 aaaccggtaa atggtagttc attcattttg aaacataaga aaaaaacact tactagaaat
    13501 ggtgtgccgt tttcagtaca aagcgaccat catgggaaag tcaagctgga tcaattgcct
    13561 ggtggaactt atcgaatcgt ttcagctgat gatcctaaag ttgctgtttc ttttggtatt
    13621 agaaaagtaa aacaagagaa gatatacttt tttgaggggc gaaaacttgt aaaagagctt
    13681 caaaaaaatg gtttttattt taaaatcaat gaataagtaa ggagagaaaa aatgatccgc
    13741 acaacaacaa aattgtctgc caaagaactg gaatctgttc tatcgatttg gctgcatgct
    13801 aacttggatt ctcatgaatt cattccatca acttattggg agaatcaagt agaatctgtt
    13861 aggaaagctt taccagatgc agtgatttac ttagcagaaa tagatcaaga aattattggt
    13921 tttgctgggg tgattgatca gtttatcgca ggaatctttg tgaaaaggga ataccggcaa
    13981 caaagaatcg gtacgcaact aatgaaaaaa ataaaagaaa ccaataaaac actgactttg
    14041 acagtctatc aaaaaaatca atcagctatt catttctatc tttcacaagg ttttacaatt
    14101 caaacacagc aaaaagatga agcagtaaat gaggaggaac ttgtgatgaa atggaatcaa
    14161 aacgctgatt tttgatgaac agaataacga aataatgctc ccagcctaat tttttgctgg
    14221 gagcattatt tcattttgaa gtcactaatt taactgtgtg aatatgcagt tgttacaatc
    14281 tttgataaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac ggcaaaatat
    14341 gaggaactat ttttccattt gtttctctaa tactcaggtc aaaacgctga tttcacaacc
    14401 tcttgataaa cggtgttcaa acggctgctt ctcggtaata agcccactag cctagaaaat
    14461 atgaaaagct attttctaac tagcgttctt attactcaaa gcataacgct gatttcacaa
    14521 cctcttgata aacggtgttc aatcagctga ccctcggtat tagctcaaaa aacggcaaaa
    14581 catgaggaac tatttttccg tttctttctc taatactcag gtcagaacgc tgatttcaca
    14641 acctctcttt cacaacctta ttttactcgt ttataatttt catcgaagta ttttccgcta
    14701 cggatatcat ctggcattcc atcgtatggt tcttcgctaa taacatcttc attgtctata
    14761 cctgcatcac ccatataagt gatcgtagca aattcaggaa caagtaattt tggataagtt
    14821 tcatattttt cacgagctgc ttccatttct gcgatatgtt cgttttggaa agtaacagtg
    14881 atttctggat gttcttcaac ccatttaggg aaaaagatca ttccgtgaag tttcttttca
    14941 tttggcataa agtccaatgc cacgtctgtc cctgttggct ctgtccaagt gattttgaat
    15001 acgccgtccg tcaatttaac gatatcagct tcttggtctt ttacccaacg gcctttgacc
    15061 attccgccat ggatacggta atcaacagta tggtcatttt tggcatacca ttcatattcc
    15121 caaccattgt catacgtata gataaagtga gttccaataa aatcttccaa ttctttaaat
    15181 tctttcatgt ttaagcatct ccttataaat taaaacatgt aataaactac atgttttcga
    15241 ttactcattt atgatagaat ggatttaaag atttgtcaag gagggaaaac tgatggcaag
    15301 aaaaaataca cttcgatata ttttgttagg gttattaagt aagaagaaga tgacaggata
    15361 tgaattgaat caatcgttca aaaatgaaat aggagaattt tggcaagcaa aacatagtca
    15421 gatttatcct gaacttgcaa aaatggaaga gcaaggaatc attcagcatc aagtagagat
    15481 cacaggtgaa aaattggaaa agaaagttta tgaattaaca gaagaaggga aggaacaatt
    15541 ggcagagtgg attcatacac ccaccaatga actaccggtt aatcgagacg aatttgttct
    15601 gaaattgtat ttcgtcaaag acgtgaatga tccggcatta gtagaaatta ttcagcagca
    15661 gcgtgacctt catgaagaaa aacgacttca tctattagag cgaaaaaaaa cgatctttcc
    15721 tactgaaaaa gaaaaacatg aaaattacgg acactacctg attttagcgc atgcgatcaa
    15781 tcgggaaaca gaatatgcaa attggctaac agatgtatta gaagaaagta accgaaaaaa
    15841 ataaaaaaat atccgaacag tgatggagaa ttcctttcta tatgaaagaa acgcagatca
    15901 ccgttcggat attcttatgt tcaaacaggc cttttttcaa gtatttatgt agcatctact
    15961 tattaaaaag cttggtactt aggagattag tggcgtttag agttctttta acaactgttc
    16021 gtagtcagct ttttcatcga caggaaggag cttgtaagtt aattcgtctg tctcgttgtc
    16081 atgaatgatg tacatcttag cattctcttc tttgaagtta ccgatttgta aaatcgtata
    16141 gcgttcgtcg atcaattcga tatctttgat tgcttttgaa aaaactttac ggacatggtg
    16201 cattttcttt tggcggattt ctgccttttc tgcagctttt gacaaagtaa atccgtcatc
    16261 taaatatttt ttgatcagtt ctacttttat gactgtaggt aaacgatatt ttctaggaca
    16321 attcgcatca gcttcgatcg aacgaatgaa tcccttttgt tcccaatacc ttaattgacg
    16381 tggagacaca cctacgatat cacttaattc actgatgcca acaaccaatt gatcattttc
    16441 caacaaacgt ttaagggaag ccccaaccat ttttgtcact ccttttgtcc tcttgcttcc
    16501 cttaattata tccgtattaa cttatgtgtc aagtaggttg acaaatagcg aatttaggac
    16561 taaagtattc tagtagtttc agaaaaaatt cagaaagaag gagaaatatg agtaacaacc
    16621 aacccgtaga tatttacgga aaaccatata atcggacact tttagttgtt gtcttattaa
    16681 ttggtacatt ttgtaccgtt ttgaatcaga ccttattgac gacagctttt cctacattga
    16741 tgaaagcttt cgatatttca gcgtctgatg tgcaatggtt aacgactggt ttcttgctag
    16801 tcaacgggat catgatccca ataacagcat ggctgatcaa taaattcagt tcaagaaatt
    16861 tatatctttc tgccatgacg atctttttga tcggaacgat tacttgcttt acagcaccta
    16921 attttagtac attactaatc ggtcgtttga tccaagcttg cggtgtggga gtatcgatgc
    16981 cattattgca aaatatcatg ctatctattt tcccgccaga aaaaagagga tcagcaatgg
    17041 ggatgtcagg gatcgttatt ggacttgctc ctgctttagg ccctacatta tctggttata
    17101 tcattgataa ctaccattgg cgtgacttgt ttggtatggt actgccaatc gttgttcttg
    17161 tcttggtttt agcattcttc ctaatgaaaa gtgttattcc attgtcaaat cctagcattg
    17221 atattttatc cgctatttta tcaacgattg gattcggtag tttactttac ggattttcta
    17281 gtgtaggaga tgacggctgg ggaagcttga aagtaattgg tttcttagtt gttggtgtga
    17341 ttttcatcgc cttgttctca tggcgtcaat tacatttgga acatccattc ttggaacttc
    17401 gtgtattcaa atcatctaca ttcacgattg cagctgtttt agctggtgta acaaatatgg
    17461 cgatggtagg ggcagaaatg gtcgtaccat tgtatattca aaatattcgt ggagaatcag
    17521 cattccattc tggcttgatg ttgttgccgg gtgcattgat catgggggct atgatgcctg
    17581 tgacgggtgc gattttcgat aaatacggcg cgaaacgttt agccatcaca gggatgttca
    17641 ttttgacagc ggcaactgca ccatttgctt tcttgacaaa aacgactcca gttttatata
    17701 tcgtgatcct ttatgcgatc cgtatgtttg ggatctccat ggtcatgatg ccggtaacga
    17761 cttctggtat gaatgcattg ccaaataact tgatcagtca tgggacagcg gtaaataata
    17821 cattccgtca aatcgcaagc tcgattggta cagctatttt gatcagtgtg ttgacgaatg
    17881 tgacaaaagc aaatatccca agcaaatctg tattggataa tacgccatta gcttataaag
    17941 atcaggcaat caatgccaca ctgtcaggtt accatgccgc gtttatcgta gcgatcatct
    18001 ttgggattct tggctttatt attgcctttt tattgaagaa aaaagaacct gttctaatga
    18061 aagcggggga taatgcatga ttattggagt tttgattgtc agcttgcttg cttttgcttt
    18121 aacgaacgtg ttcgctaaaa aaacatggca aaccttttta tctttgattt tcggactaat
    18181 cttcgtcgct tcactaagtt tgatcgtcgc taatttgtcc aatcactttg gaatggaaaa
    18241 agtaacggaa acaaaaacag aaaaaattgt ttccagtgct gattcccaag gagcagatat
    18301 gcttttgtat aaagctttag ggaatggaaa agaaaaagtg tatctttacc gaacaaatga
    18361 aaaacaagaa aaaccaaaag caactggtac ggataacgaa acaaataaag tagaaaagac
    18421 agacggcgat gctgaaaaag tgacgaaaac tacttattgg gaatacaaaa acgacatgta
    18481 taaattctgg ttcaatattg ctgataacaa tcacgaatat gacagccgag tgaatacatt
    18541 caaaatccca gagacatggg tagaattaag tacggaccaa gcagccaagt tagctgaatt
    18601 agtgaagaaa cagcaaagta cgatggaaag tgaagcaaaa gcttatgttc aagacggtat
    18661 ggtaaaagca atgactgaaa atccaaaaat gagcaaagca gagcaagaac aacgtacgaa
    18721 agccttagct gctgaattcc aacaacaagc attcgcaaaa ttagtgaaag aagcaaaagg
    18781 cgaataatat tttgaacacc atgta
//
LOCUS       DAYYEF010000051        18450 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000051 DAYYEF010000000
VERSION     DAYYEF010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.053"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(456..1766)
                     /locus_tag="ACHA1B_002098"
     CDS             complement(456..1766)
                     /locus_tag="ACHA1B_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004650 - polygalacturonase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 28 protein"
                     /protein_id="HFM8702847.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1778..3196)
                     /locus_tag="ACHA1B_002099"
     CDS             complement(1778..3196)
                     /locus_tag="ACHA1B_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM8702848.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3436..5004)
                     /locus_tag="ACHA1B_002100"
     CDS             complement(3436..5004)
                     /locus_tag="ACHA1B_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HFM8702849.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5008..5418)
                     /locus_tag="ACHA1B_002101"
     CDS             complement(5008..5418)
                     /locus_tag="ACHA1B_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HFM8702850.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5415..6338)
                     /locus_tag="ACHA1B_002102"
     CDS             complement(5415..6338)
                     /locus_tag="ACHA1B_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030599 - pectinesterase activity
                     [Evidence IEA];
                     GO_process: GO:0042545 - cell wall modification [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pectinesterase family protein"
                     /protein_id="HFM8702851.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6335..7213)
                     /locus_tag="ACHA1B_002103"
     CDS             complement(6335..7213)
                     /locus_tag="ACHA1B_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HFM8702852.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7200..8537)
                     /locus_tag="ACHA1B_002104"
     CDS             complement(7200..8537)
                     /locus_tag="ACHA1B_002104"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HFM8702853.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8540..9643)
                     /locus_tag="ACHA1B_002105"
     CDS             complement(8540..9643)
                     /locus_tag="ACHA1B_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HFM8702854.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9717..11225)
                     /locus_tag="ACHA1B_002106"
     CDS             complement(9717..11225)
                     /locus_tag="ACHA1B_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFM8702855.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11191..11883)
                     /locus_tag="ACHA1B_002107"
     CDS             complement(11191..11883)
                     /locus_tag="ACHA1B_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HFM8702856.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11905..12879)
                     /locus_tag="ACHA1B_002108"
     CDS             complement(11905..12879)
                     /locus_tag="ACHA1B_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702857.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13179..14051
                     /locus_tag="ACHA1B_002109"
     CDS             13179..14051
                     /locus_tag="ACHA1B_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8702858.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14509..16707)
                     /locus_tag="ACHA1B_002110"
     CDS             complement(14509..16707)
                     /locus_tag="ACHA1B_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702859.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDHNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16939..17931
                     /locus_tag="ACHA1B_002111"
     CDS             16939..17931
                     /locus_tag="ACHA1B_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8702860.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17991..>18450
                     /locus_tag="ACHA1B_002112"
     CDS             17991..>18450
                     /locus_tag="ACHA1B_002112"
                     /EC_number="1.1.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="catalyzes the formation of D-tagaturonate from
                     D-altronate; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HFM8702861.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRF"
BASE COUNT         5505 a         3825 c         3043 g         6077 t
ORIGIN      
        1 gtttattgtc ttgaattgaa tcaagacgcc ctacacattt ggtttgtctt actttgttca
       61 gttttcaaag gtctacttca tcgagagtgt ttcccgattc atttttggct gccgtagcaa
      121 cttttatatc atatcagaga gacaaacgat tgtcaactct tttttaaaag tttttttcga
      181 tttcgttttt cgaaatcttt cagcaactca tttatcataa cttatcgttt gttatttgtc
      241 aagaactttt ttgaagtttt tttcgataga atcaagcttc gcaagtggtt ctttttaacg
      301 acttagttat cttatcacgt ctaaaaacat gtgtcaactc ttttttggaa ttttcataaa
      361 atgtttcaat gaagcgcgac aacgttgttt aatatatcat taaaaaaaat aaaggtcaag
      421 ctaaaatatt atttaagctt gaccttatta taatttcaac gattgtcaaa agtattgttt
      481 gcagctgtgt tgccagtttc tatagataaa tcacagcttt tgaaacataa gttttgtact
      541 gcttcgattc gcccgaattc ttttgcagtt atttggcaat gagaaaagca gacatcttct
      601 ataggctttt caggaaatgc tactaaatca aaagctcggg aaggaagtga gtaacctgga
      661 gaaaggcatg cctgtacgtt tttgatgtgt atgtctttga ctttcgtcat ttgctttgat
      721 tcaggtattt cttcagccac tgcttgccaa ctttctggca tttgagcaag gtcattgcta
      781 ttttttctat tgtattcatt atgccagtcc attatccaag aaaaaggaaa ttgtacatca
      841 atcatattca gattttctac cctgatattt tcgatcactc cccctctttc ttttgaagat
      901 ttcattcgaa taccacagtc tgactgaaaa aaatcgatat cgtgaatata tacgtcacta
      961 actccagcac taacttcgct accaatagtt acaccgtatc ctgaacggat tttacatcta
     1021 gcaacctcga ttcttgatga ttttcgattg actcttgcac cattgccatc tctgccagac
     1081 ttaatagcaa tacaatcatc accacaggcc aaatcacatt catagacacg cacatttgtt
     1141 gaagaatcaa tatcaatccc atctgtactt ggtccatcat tgttgcggat gattactttt
     1201 tctactaata catcgttaga ataagtgatt tgcaagttcc aaaaacctga tttctgaaaa
     1261 atcaaatcac gaacaacaac atgttctgca tgatacagta aacaagcgcg tggacgttta
     1321 atagcataat ccgcaatcca acgaagtccc ttttgatcgt attcagctct tgtcccgctt
     1381 ttttgatctt ttccccaata cagctcccac caatggtctc cttgaccgtc gattattcct
     1441 tttccttcta taagaatatc tttcgccgag agaacattca aaatcgctgc tggccatttc
     1501 atttctacgc cggctactcg tgtatcgatt tctggaaatg cttcgatatc tgttctcccc
     1561 ttgaggactg caccttcttc aaagataaga tgactcttat cttttaaaaa aagggctccg
     1621 actaaataaa tgccttttgg aataaataca ggtaagtgtt ctttcgcacc ttgatcgatt
     1681 gctttttgca gtattattgt atcatcttgt tgagtgtcgt ttgttttaaa gttcaaagca
     1741 ttgataatcc ctttttttgt ccgcaatacg tttctcccta tctttcattg atttttttca
     1801 attcttcacc aataaataca gtttttgaac gattcagtgg gtaacctact agcaaaatga
     1861 ttgcggatac aaataagcag aatgctggta acaagtttgc catcgtataa atcctttctt
     1921 gtactaaaac tgattggatg gctccacctg ttgtagacga ttggtaacca atgagtgcca
     1981 gcataaatcc gcctaccgct cctgcacatg cttgtcctac ttttctcgca aaagaattta
     2041 ctccatatac tgttccatct tctcttaagc ctgtcttata ttgatgataa tcaatcacgt
     2101 cagtaatgaa tgcccagacc atcaaattga ataaaccaga tcctaaagta gcgataaata
     2161 aaagaatcag atatacccat gcatttgtta tatgaaggaa atacatcagc aagtacatac
     2221 atgaagaagc aagtaacgca aatacgcttg cttccttttt accaaataat tttgtcagct
     2281 ttgtagcaaa tggtgctaaa actactactg ttccgtaagt aaataaaaga gcaacagaca
     2341 ttgcttgttt attatggaag taatcattga ataaataagt catattcgtc ccagctaaaa
     2401 tctgattgat cacaatgaaa atgtcaacaa tgactaaaat aatcagtgct cgattagcta
     2461 acaaaccttt taccaactga gaagcagata ctttttcgtt tttgacaact cttactcttt
     2521 cagtagtcaa tttacaagtt aacatatatg cgacaaatgc tattgcagca catccgattg
     2581 aaatccaaaa gaaatgattc cctgaaacga cttgttgtcc actcttgtta tgggtataca
     2641 ttaaaatcgg aatgaagaat cctgtagttg atccgccaat cgcagaacca atgcttcgga
     2701 acgtggacaa cgaggtgcgg tcattaggat ttgagctaat tgctgctgcc attgctccat
     2761 acgggatatt gattgttgag agaaaaatcc cataaacaat gtatgaaaca aaaatataag
     2821 caatcttcac cgtcattgga agatgttgga cgaatggcaa aaacaaaatg acagtcacta
     2881 agcaaaatgg atacttcatt tttctgatcc aaggaataaa tcggccagtt tctgttaact
     2941 ctgagacatc acataatctt ccaaccatca catcagcaaa cgcatccaaa attctcgaaa
     3001 tcaagaataa cgtacctacg attgcccctg aaacgccaag aacattcgta taataaatca
     3061 tcaagaaact attgactaaa cctaaaataa aacagttacc tagatcaccg aacatgtagc
     3121 ctatcttatc ggaaatccca aattcctttt tttctttttt tattgtattt gctgtaacag
     3181 cattttgtga aagcatttga attcctccta cctcttctag taaacgtttt caaaattata
     3241 actctttttt tcttgttttt atattcacaa tgttggcttt ttattgcatt atcttgacag
     3301 ataaaaaaca aaaaataatc taaaaacatt gatgcataag attgataact ttttttacat
     3361 aacaatatat acaaacaaaa aaattcacta actagtgaaa ataagttagt gaacctcatt
     3421 tattaaagaa ttaaattaca gatgatcttt tccatcatac ttgaaaaact caaaatcagc
     3481 ataacttcct ctttttttat ttagatcatg cactgctatc ccgataaaat ttccagtaaa
     3541 ccctcctgag agtatacaca tgtttttttg cggacctact ttcttccatt cttcagttga
     3601 tacgtctttc aaatgaaact gtgctgtctc tttctttaca gtgactttca aaaaagtctt
     3661 cttttctgtg agtggaatcg tccaatcttc tatttgtgct actccgtttt ctgattctat
     3721 catacgtagg cattttccct tgtcctcatt ccaagtaaca taacaataaa tataattgga
     3781 ttcatttaag tacagtacca gtccagccat ctgattaaaa ttattaggca tgtattcaaa
     3841 tgctgtctcc gcatcaaaag taaaatccgt ttgccgaata gctaacaaat gatgttcgaa
     3901 ggtagattga agagattcac cggaaatcag acgtaaaaaa cctggtctac attttgtatc
     3961 acaccaatca gcatttggca aaatgcgtct ggcattccag ttcttcttta gctctccttc
     4021 aaatgtatcc ataaactgat gatctttttc ttgttgtacc tcttcatttg tctcaatcat
     4081 tatttcttcc atcggagttg tctggctatc tttaagtctt aaccaatcgt cggacgtcca
     4141 atacacttct tgaatagcgg tttctcttcc caaaatagcc gcaccgttta atggtctggt
     4201 acaaagatat gtcatgtacc atcttcctga cggggtttgt actaagctcc catgtcctgt
     4261 acattgcaat gtagaagcag gtttgtcact agctgtcagc ataggaaaac caggatcaag
     4321 ctcgtaagga ccagtaatat tctttgctcg gcaaactgta actgaatgtc ctcttcctgt
     4381 accgccttct gccgtcatca aataataata cccgttacga aaatacaaat gtggtgcctc
     4441 cgttttcgct aattctgtac ctgcaaatat tttatagatg ggaccatcaa gcttcttctt
     4501 ctctgcatca tattcttgta atacgatacc gctggattta ttcggtgtgt ccagacgata
     4561 atcccatagt tcattgacaa gccatttttt tcccgtttca agatcatgga acaaagaagg
     4621 atcaaagccg ttactattta aataaattgg ttcggaccaa ggacctgtga tctcagatgc
     4681 agtgatcaaa taattgtgga catctttaaa cggacggcct gcacttttga catctgtgta
     4741 aacaagataa aacaatccat cagcataact gatctgtggc gcccatatac ttccatttgt
     4801 aggatttcct tgcaaagata cttgagtggt caaaatatcc gttgtatgtg accagttgac
     4861 taaatttttc gactcatata ctcggattcc tggaagccat tcaaaagagg agacaataat
     4921 gtaataccgc tctttcactc ttaatatatt aggatctgga ttgaatcctc ttaaaatagg
     4981 atttttcact ttgatagtct gcatgattca ggctcctttt ctcattctta ctcgatataa
     5041 actgaatgcc ccagctgcga aataaaaaaa tgcaaaagga aacgcaataa actgagtgcc
     5101 aatcaacaat atgaatcctg ttataaaata caaaccagtg gcagttgtta agtattttcc
     5161 tttagcagtc aaaaacaatg ctactgctaa aaaagcaagt gaaataaaca acacaacggc
     5221 aaacagacca gtcatgtcct gtaataatcc aaatgtattt tctaaagaca aagttgaatg
     5281 atctacagca agcgactgat aacttttttt aaactctgac gcagacatat tacttaaagt
     5341 aactgctaac ccgccaaaga aaatcaaaga tagactgcca ccgaccattc ctagcaatag
     5401 ttcccatttt cttttcattt ctgaaccccc tgcttttcta aatgtatcca ttcaggtctt
     5461 ttgatcgatg tttcataatt gttattacgt tcagagaatt tgacagtctg ttcatttttc
     5521 ttgtcatccc aattatccca accagttggg tgaacatgcc cacctatctt acacgcttca
     5581 aataagacat ttgcatacgg acgccacggt cttcctaaat agacgtttct agtatcaggt
     5641 tctgcagtca aggtacagct ttcaaaacga taccctgttt tttgattttt cggcgtagat
     5701 gctgctgtga tgtatccagg atttttactg gctaagctat ggatatgaca ctgatgaaaa
     5761 acggcatctg ccccaccaaa tatgaaatcc accgttcctt caatccagca atattcatag
     5821 gtctgacgac aatactcagg attggcagaa gccggtgtac aaaaaggagt accatctttt
     5881 tgcaaatcag gcaacggacc cgtgcataag gtatcctgat aaccagatag tcgacagttt
     5941 tttaaagata cgcgatctcc tgaattgaat aaagcaacag cctgtcctac cttttctcct
     6001 ggacctgctg tattttcgat gtgaagattt tctaatacga cattcgatcc ttctaagaaa
     6061 aaagtagcac ttcggaaagt ccctaactgg ctaccgtcaa gatactcctg ttttgcaaaa
     6121 cgattaccgg agataactac tgttcctgct cccacaagtt taaaattgga taatctgctt
     6181 tctatatatt catcatatct tccttctttt actatcaaga cctttggatg gctatccggc
     6241 aggcctgcca aataatcgat tccttcttgg atagtttcaa aatccgtcgg ggtatctata
     6301 gcattctttc caattatcag tttgtctttc atcctcataa atgctccctt atgaattgtt
     6361 tccaaatatt tctcatttct tgtgtttcca tatgaccgcc tgttaaagaa aaagaagaaa
     6421 agttttctgg actacccatt gattgatact ttttgtccag cccttttctc agcttcagta
     6481 cgccttcgtc caagcacatc gtatcgtttt ttccaactaa gctaagacga gggcgcggag
     6541 cgattttttc ttggattgct aacgttgtat aagctgtcaa tagatttggc acatagtaat
     6601 aaaacccatg atgatctagg cggcgatgta gcaaaagtat ttcgatgtcc acctgtgccg
     6661 ctagatcaat acaaactttg acacgagaat ccaatgctgt cacccaccag cttaataagc
     6721 ctcccataga aagaccaatc gttgcgagcc gttgagtatc tgtgtcttcc cttgtctcca
     6781 aataatcgat caagctgatc acatcataaa tacgcattcc ccataacgtt tttcctgtta
     6841 ataaaaattg tttgaacaac tcgctttcag aaatacctcc gcgttcttca aatccccaag
     6901 catcaatcga ccaaacagca tatcccattc ctgtcagtac ttctgcaaaa gatggagaag
     6961 ctaagtaagg agcaccatgg atcaattcac ttttcccgac tgaaaaatct ccgccgtgag
     7021 aatgcaggta aaggaccggc ggaaacggtc cttctttttc tggataagca tagagggctg
     7081 gtactgtttc caattcattt aagtacaatt gatagtattc aagcataaaa ccgttttgtt
     7141 tttctcggta taatcgtttt ccactagggg tatgtctgct agatggagca cctaaaaaat
     7201 cattcaactg cataagcaaa gtttttacga acaaccagtt catccatatt ttctgattga
     7261 tttgattgga atttctcaat actgatttct ttagtatttt ctaatagaaa tgctggtccc
     7321 tcgtgatttt caatcgacat ctggttaaag gaaaccttac ccgcaaagcc aatataaaat
     7381 ccttgtctgc tcatttcctc tattcctgtc atcatagcag gaacaccggg aactgcatct
     7441 tgggccatcg agacatcgat attgtcaaat gtgatttctt gtatgaattg ttccgctaat
     7501 ccataaataa aacctgcaga agcatggaca ttccttgccg tgatattcga aaaatggatc
     7561 cttctgaatg ctggtgtccg ttcatctatc ggataagcct ttttttccca tacatacggt
     7621 tctttccctc gcggaccaca gaaataataa agattcagta taaatggaca catcacatta
     7681 tccatgacta tattggatac tcgaatatct tcaacgatcc cgcctcgacc tcgtctagat
     7741 ttcaatcgta ttcctcgatc agtttcttgg aagatacaat ttgaaatggt aatattacga
     7801 atactaccac tcatttcact tcctaatacg acaccgccat gtccatggac catcgtgcaa
     7861 tttgtgatcg tgatattttc gcaagcgatc ctttcgtacg tatcttcagt ccctgccttg
     7921 attgcaatac agtcatctcc cacgtcaata tggcaattac taatacgcac atttttgcat
     7981 gattctggat caattccgtc tgtatttggt gaatccgctg ggttcaagat cgtcaagtta
     8041 tcaaacgttg cattactgca aagaatcggg ttgatcgtcc aacttggtga ctggatcaat
     8101 ttaatatctt tcacagtaat tcgatgacag ttatggaaac tcatcaattt aggacgagga
     8161 taagcgagat tatctggttc atttctaaaa gtatgccacc atttttttcc atttccatct
     8221 aatgtaccga aaccagtgac agagatgttc tctacatttt gagcatagat acaggaagca
     8281 taaacttttc gatggactcc ttcccaacgt gaatgaacaa caggataatc ttttggatcg
     8341 tcagagaatt tcagaaccgc tcctgcgctt aaatgaagtt cgacattgct ttttaaaaat
     8401 aaagctcctg ttagaaattc acctgctgga acaactacgg tcccgcctcc gtcacttgct
     8461 gcagcatcaa tggcttgttg tattgcttca gtattcaatt catcaattga tgcgccaaat
     8521 gtcaaaatat catacatatt tataatgcct ccacttcaat caatgcttgc aagaatgcac
     8581 caacgccttt ttgatcatta caaataattg gttcactgat gtagtaagca tatgaaccat
     8641 ctcgctgatc tgctccgcct aaccctgcta cttgacagtt tttattcaag ttcagccagc
     8701 cttcttttgt ttccagaaca aattcatcaa gtaatccttg atgtgatttc ttcacttgtg
     8761 gaagccattc ttctttgttc agcagtccca aacgtattcc tttagccatt gcgtaaacaa
     8821 acatactact gccggaagct tccagataat ttcctttccg ttttgtttct gttgttactt
     8881 gataccatgt cccgctgttt tcttcttgat atggaagtaa tgcagccagt gtcttttcta
     8941 gaatttcttt cagcaaagaa caatctgttt cttcatgaag taattcatag gtatctgctg
     9001 cagccatcaa ataccagcca atcgatcggc tccaaaaatg atgggataga cctgtttttg
     9061 gatcagccca tggttggacc ttcttttcat cccatgcatg aatcagcaaa tttgtttttg
     9121 gatcgaatag atgtttataa ctgatttcaa actgtctcaa aacatcttgg taatcttttt
     9181 cttcactaaa attctggata aattcagcat aaaaaggaga acccatatat aagccatcca
     9241 accaaatttg ataaggataa atttctttat gccaaaaagc tccttcggat gtgcgtggat
     9301 ggtttgccaa ctgctgggaa aggagttctg ctgctttttt atatttttct tcgcctgttt
     9361 ctttgtacaa taaaaagaaa agctttcctg tatttacatg gtcgatattg tattcttcaa
     9421 cgctgtagcc acggatcgtt ccatcttctt gcacgaaata gtcgatattg tcttttatga
     9481 aatcaaaata aattttttct tgggttcgtt cccaaagtaa ttggaaccct ttaagtacga
     9541 cgccatagtc ataagaccat tttcctttat accacttttc ttcatataag cgaggtgttc
     9601 tttccatgat actttttgct aatttctttg accagttttc cattatttgc tctcctttaa
     9661 aaattaaaat aggatttggg acaaatacca agaagtattt gtcccaatcg tctatattac
     9721 tgtgccgctg ctttgtatgc ttcctcgtac tcttgtgtga ttcgatcgcc tccttgtgct
     9781 ttccagtctt ctacagcttt tttgaatcca tcttcgtcaa gctgtcccat gatgtattgc
     9841 accgtagcat caatgacgat tttttcaatt tctgatccta cttcattgtt cgtcggtgaa
     9901 tccaatggca cagaaggatc cattacagca aattcttcat tttctttgat caattgatta
     9961 gagaattctt tttcagggtc tgtatctttg aaagagaacg tcacttcact aggacgagag
    10021 cttgataacg gttgcacctc ttgttgccaa agatccatat cgataaattc gatagaacca
    10081 tcatcattca attcataatg cgttccttcg ataccgccag tcatcaattt atacacatct
    10141 tcttctaaaa gatcatcaac aaattgaagt aatttcttca attgtgcttc gtcttttact
    10201 tgagatttgg gaaatgctag caagccgcca ataccatttc cttctgacca aacatgataa
    10261 ccgccgcctt caccatctga gatcttgttt acaggcacta attccatatc atcttgaata
    10321 ccttgaccca tcgtcttcag attcttgata tccaccattc cagtgtagat tccagttctt
    10381 ccttgtgcaa attgttcttg ctgatcagtc ttttgggtaa ctgcaaagtc ttgtgccaaa
    10441 tagccattct caaatagatc tcttgaaaaa ttcaaagctt tcatatactc ttctgtatca
    10501 aattctggag tgaatttgcc attatcgtct acagcccagc catttggtgc tccaaaataa
    10561 gaagtgaaaa gtttaaagct ggtataacga atatcactag gcgcacgatc gccaaaacca
    10621 actgtgtcgt ccacaccatt tccatcagga tcgttttctg taaattgttt agctacttca
    10681 taaagctcat ccatggtagt tggaacatct agtcctagat tatccaacca gtcttttcga
    10741 atgactaagc cagcacgagc gtagtctttt tgtatcggta cgccgtacaa ggcaccgtcg
    10801 atactcgcag cttcgattct atcttcagaa atttgactta aatttttata gtcttttaaa
    10861 tattctgata catcccagaa tacgcctgat tttaacgcat tgcggacaga agagtttttc
    10921 aacatcgcaa tttgaagtgt aacgatatct cctagttcat cagaagccaa tgcagttgtt
    10981 aatctttctt cttttgaagc atcaggaatc cagttgaatg tcagttccgt atcggttttt
    11041 tcttcgatca agttcacaat cgtgtctgta ggcggtgaag catgatgcaa aatatttaac
    11101 caagtgattt tagcttttcc atcttctgtc tctgaagaac tgttacttga actgctgccg
    11161 catgcggcaa gtgctagaat tcctgcaaaa ctaagaccta attttacgag cgttgctttt
    11221 ttcataaatt ttctccttca ctgttttaat aatatttttg ttttcttctg ttttttctgt
    11281 atatgagttc ttccattcca aatggcaaaa tatagaattt gctgtccacg tgactgcgga
    11341 aaagaagaga ctgccaccga taaaggttaa aacacctggc attgtttgga tgatcatcag
    11401 ataaatccct accatactta atatcaacac taatgagtaa tgaagatgtg agaatccgaa
    11461 taaaaatgcc attttcattt tgaaaaaata tcctttccaa tcataatgag ccatgattgg
    11521 gaaaatatag agtgctgaga gcacatatat gaacgcagca atatacaaag cgatcctaag
    11581 ataccaattg tgtatgaaag aaagatccac aagtaaaaca atcccgatgg cgccatatat
    11641 ccagctcatc agcaaggttt cacgatagtt ttctttaaaa tatgtgaagt acgttttcgt
    11701 caaaggaaac gtttcttttg agcgcagcca ttttctaatc actgcaacca tcgcatacga
    11761 tgcaggaccg aaagtaaaaa ctcccaaacc tgcgatgact aaaccgcccc acagaaaatt
    11821 caaataaacc aactgtaaaa tacgatttag ccttccgttt attttatcta atgactgcag
    11881 catatctttc cctctctttc tatcttagta aacgccgtct tctcctagct ttttggcaat
    11941 cttattagct aaaattacca taaacaatcc tacgacccct ttaaacaatc ccattgctgt
    12001 actgaaactt aactgtccat tcttcaatcc agctgtataa atataggtgt cgaaaatttc
    12061 tgcaacgctt cgattcaatg aattcaataa caagtacata tgctcgaacc ctaagtctaa
    12121 tgtctgaccg atttttagaa tcagcaaggt aatgattact ggacgaattg ccggcaatgt
    12181 aacatgccat gttttgcgta agcgtcctgc tccatccatt tctgcagctt catacaactg
    12241 tgtatcgact gcagttatcg ctgaaaggta gatgatcgta gaccagccca actctttcca
    12301 gatcacttgt ccgatatata ctgtgcgtgt ccattcaggg gatgttagaa aactgatttt
    12361 ttcaaatccc attgttgcaa ggaattcatt caatacccct ccgtcaacat tcaaaaatac
    12421 ataagtaatc gaaacaatga ttacccaaga catgaagtga gggatgtaaa tgatcgtttg
    12481 aatcccgttt ttcaatcgtt tgttcgttac ttcatttaat agtaaagaca aaatgattgg
    12541 catcggaaaa aacacgaaga tatttaatcc gaacaagatc aacgtatttc ttaataatgt
    12601 aaagaatgtc ggttctgtaa acaaacgaat gaaatgtttg aaaccgaccc aaggacttcc
    12661 cattattcct aaaaatggtt gataatcttg aaaagcaata acgagtcccc ccataggaag
    12721 atacctaaaa atcaagaaat aaaggactcc cggcagaatc atcacatata aaaatttatt
    12781 cgttttgatt cctgcaatta ttttttttcg tcttctgagc ttttcttctt ttttcgatag
    12841 cgtcagttga aatggttctt gtttctttac actttccata agcccctcct tagttttgtg
    12901 aatgtttgct gcttatgact tcatgataga taactatctg aattacgtat ataatcattt
    12961 ttaccgtaag taaaaacgct tacatagcaa tgatttttgt gctatacaaa acgataaagt
    13021 gtattttttc acaaataaac tacgcatagc aaaccttcta tttttttcta tctgacactt
    13081 agcataggaa atgattatat acgtaatctt tcaccgatga taaattgaac atatagaaac
    13141 agaaacattt aatttatttt gaggaggagc ctatctatat gaaaaagaaa gtctctatag
    13201 gagaaagaag ttttacactt ttcaacaata cgtttctaat tttgctagct ttgatctgta
    13261 tcgttccttt tttaaatatc atcgctacat cttttgcttc tacacaagaa gtcgtcgcga
    13321 aaaagtttat cctttttcct actacctttt ctttagacgc gtatcgctac attctttcta
    13381 cgccgaccat ttttagagca cttgctgttt cgattggtgt tacaggtgtc ggaacgatcg
    13441 tcagtatgtg tgcaacttca ctgatggcct acggtctttc cagaaagtat ttgtttggtc
    13501 gaggtttcgt caactttctt gttgtatttt ctatgttgtt cagcgggggg atgattccaa
    13561 cgttcttagt tgttcgttct ctagggctgg tcaattctta ctgggccatg atcctgcctg
    13621 tggctgttaa tgcaatgaat atgatcatta tgagaaactt tttccaagcc ttgccggata
    13681 gtttggaaga atcagcaaaa atggatggtt gcacagattt tggtgtattt ttcaaaatta
    13741 tgctgccatt agcgttaccg tctattgcta ctatctcgct tttttatgct gttacttact
    13801 ggaacactta tatgactgct attttgtata tcaacgattc atctaaatgg ccgatacaga
    13861 ttcttttacg ccaaatcgtc attgtatcaa gtgggatgca agcagaaagt agtgccgttg
    13921 atgtgattcc accagcacaa acagttaaaa tggctgttat cgttattgca acagtgccta
    13981 tgctgattgt ttatcctttt gttcagaaat attttgtcaa aggagcactc gtaggttctg
    14041 tcaaagggtg attatgtact gaacgcaaaa tggtagttgt gtcagaagtg gtcagcttca
    14101 agaaataaga aggcatttac gaaaattgct tcttaaattt ttgtgaaatt tcggcttatt
    14161 tttcgaagaa tctactcctg gaacaccgtg tatcagaggt tgtgaaagag acgttcagcc
    14221 ttgagcgatg ataaaaactc tcacaaacat tgcgacgagt aacccacagg agcaataaga
    14281 agcgattttg aaaaatagct tcccatattt cacaaaatta tgccttattg tcgatagcct
    14341 gtctcttgaa cgccatttat tcgtaaaaaa gaactgtgac aagacttttg tcacagttct
    14401 ttttgcgtgc ttagccttga aatttaacta tccataaata caaatactag ggttattcta
    14461 acttctttta ttgcttgaat cagtccacaa gaaaaacagc ctcttgattc acaaatattt
    14521 ttttcgatat tctcccggcg taatcgattc cttcttttta aagaaacgaa taaaattttg
    14581 cggatttcga tattgcaatc tttctgcaat ctcttttacg gagaggttag tctctttcaa
    14641 ccattttttt gctacctcta aacgatgatt ttgaacaaaa tcaccaaatt tttctcctgt
    14701 ttccttttta aatacattac ttaaatagtt agggttataa tgcaacctat cagcgatcac
    14761 atctaaagac agatcacgat catattctgt gtagacgata tgcataatat tctccgacaa
    14821 atttttaaat tcatgatcag tgattgcttg agagcattct gtgattggca gaactaattg
    14881 ttctaaaaca agtttttcta gttctttggg atgataattg ttcagtgctt ttacataaat
    14941 ttgtttcatg ttatcaaagt tttttgaatc tactcccaat aactgtccta attgaacgag
    15001 ttcattgatc aagcggaccg aaactacttc ccgactcaaa ggatttttat tttgtgcaaa
    15061 caatgcatca atcaattcat gtactaaatt cttcacttcc tgatttccag aacgaatggc
    15121 ttcaaacaat cgattttgtt cttctatcgg atatctaata agtgtttttt catgagcagc
    15181 aggaacgatt tcctgataaa aaataattga acttggacca gtatttacac gataatacag
    15241 ggcttctttt gcccgatcaa ccgattgctt gctttcattc agcgtttcga accggttact
    15301 gatgcctata ctgatagtta aattcaagta ttcttttaca cgtttttgaa tgagtcggca
    15361 atactccatg acttttttgc ttgcttctgc atcatcttta tccattcgat aaatagtggc
    15421 ttgcatttct tcattcaaaa cgatcggcag cattcgattt tcctttggca caatttccgt
    15481 gatcatgttg ttgatcgcta aaagtagcaa atcacgctcc ccaccgtgac tatcttctaa
    15541 cagatcgatt tgaaccaaag ctgtataata gcagtcattt tgagaactat aaccaaattg
    15601 ctgcaaccgc tgatctagtt ctcgcctttc tactcgattt ctaaataaac taagtacaaa
    15661 tagcgtttcc agctgtggct tttgggtaac taagtgtgca cttaacgctt ctttttctcc
    15721 tatgatccga ctgactgatt gagcgaccaa atctagttct ttcccactga atccttttga
    15781 tttaagattc agacgttcct gtatttgaga aatcggacgg gcaaatctgt ccgaaaataa
    15841 gtaggaaaga agaccaatga gtcctaccag tgttaaagac actgcaacta gcccgattct
    15901 cagattgcgg atcattgcgc caattgcact agagtcaact tctaatctgt aaatccaatt
    15961 attataatct gatttcagta ctatatacgt tttatctttt tctcttatca ctttcagctg
    16021 attgtgatct agatccacgt ccgttaatac agttggttgc tctttatttt ttactgtctg
    16081 agtagtaaaa aggttgccaa cttcgttttc aatagaaagt atgtcttctc cactttcacc
    16141 aacaacttgt tctattgtat gtttctctat cgtagcaatt cccaatgcat atttttcttt
    16201 ttcaaacatt ggcaaagaaa tcaccatttc gattcctttg tttttctttt gccaaaataa
    16261 attatttttg ttatttatgt acttctgttg atacttttca atttcctctt cggtcagttg
    16321 actcaacgat ccattgatta ctccccattt accagccaaa ctgactaaat cataattatt
    16381 atcatccata acaatcgttt ctataaaatt tagttctttc ctgatttcag aataagtgga
    16441 gtaatctgta tatgtcagcg gatgcttgaa tatgtccgag aaatttttgg tcgaaccata
    16501 cgtagaaaac gaatattcaa tcgttctaat tttccattca acgttagttt taacttgcct
    16561 gagcaaattc tttttgtctg ttaaataact cgattcgatc gattcatagg tattctggta
    16621 aatgaataaa ctaaatccta tgacaagtac ggctcctaat aaaaacatcg gtaaaaatat
    16681 tttataaaat actgtacttt tcttcatttt cttcctctcc tccttttaaa ataaaaggct
    16741 ttcatttttc tgtaaaattg atactcatct aattaaatga gcattccccg ctttcaagaa
    16801 tagcataatt aaaaataaaa atccaagtaa tttttaacgt gtgcaatctt ttcatatcaa
    16861 agatctattg acttatcgta gttatcgtaa tatgatgaat gcgttaacaa aaagtgaaaa
    16921 agtaaggaaa atgatggaat ggtaacgatc aaagatgtcg ctaaagcagc tggcgtttct
    16981 catacgacag tttctcgtgc tttgaataac agcagtttaa taaaaaatga aacaaaacaa
    17041 aaaatacgac aactagctaa ggaaatgaat tattcgccaa actatagtgc aaaaggttta
    17101 gtgaatcaaa aaaaatatct aatcggacta tttttctcaa gtttgcataa aggaacttca
    17161 tcaaatttcc tagcagattc cattgcaggc atccattcag tattagacac aaattacagt
    17221 ttatctgttg aaagtatcga tgttgttgat ttaacagaaa tcaacctgca acgctacgat
    17281 ggactgatcg ttatgagtca aagtgatgat gatcagcctt tcatcgacta tctcaaagaa
    17341 aaagaatttc ctttcgttgt tgtcaatcgt cacatcaatg atccagcggt tatcaacgtc
    17401 actgccgatg atgcggccgg tgttatgcag gcagtagatt acggtattgg atgcggacat
    17461 acgaagatcg cttatattgg cggaaagaaa aattttcgtt cgacaaaaga acgggaaaaa
    17521 ggggtattga aaagtctaaa aaaagcgagc atccctgtca atccagccta ttttttaaca
    17581 ggagattaca gcttagaaag cggcctccaa aacatggaat acctattatc actttctgac
    17641 ctgcctactc tggttttttg cggcaacgac gacatagcga ttggtgcatt gagagctgta
    17701 catttagctg gcctccgtgt tccccagaac atttctctga tcgggttcga tgattctcca
    17761 gtcgtctcct atctcaatcc gccgcttacc accgtacgta agcctttgaa agaaatgtgt
    17821 caagaaggaa caaagctttt actagatttg atcgaaggca ggacgatcga acaatctaaa
    17881 attgagctct ccaccttgtt gatccttcgt gagtcgatca attacttgta aactacaagt
    17941 aattttatat aaaaatgtta acgtgtgcat aacacagaaa ggaagtttat atgaaaaaac
    18001 tgacaaaaga attagtgaaa aaaaacgaag cacctgtaaa agttcttcag tttggtgaag
    18061 gcaattttat gcgtggattt attgattggc agattcagca gctgaataac caacaattgt
    18121 ttaaaggtaa tgttgcaatc attcaacctt tagaacaagg tcttggaaat atgatgaacc
    18181 agcaagataa tttatatacg gtcattttac aaggactcag caatggcgaa atcgttgata
    18241 cttccgagat tatcaccgta gtagaacaaa tgatcaatcc ttatgatgaa tgggatgctt
    18301 atctatctct agcagaaaat gacgacttgg cctatatcgt ctccaataca acagaggcag
    18361 gaatccaatt cgtggagact gataatttaa cagatactcc cccacagagc ctcccgggca
    18421 aactgacagc ctttttatac cgacgtttca
//
LOCUS       DAYYEF010000052        18062 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000052 DAYYEF010000000
VERSION     DAYYEF010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.054"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            168..362
                     /locus_tag="ACHA1B_002113"
     CDS             168..362
                     /locus_tag="ACHA1B_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702862.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="ACHA1B_002114"
     CDS             631..930
                     /locus_tag="ACHA1B_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702863.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="ACHA1B_002115"
     CDS             complement(1027..1461)
                     /locus_tag="ACHA1B_002115"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8702864.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="ACHA1B_002116"
     CDS             complement(1693..2403)
                     /locus_tag="ACHA1B_002116"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_function: GO:0008742 - L-ribulose-phosphate 4-epimerase
                     activity [Evidence IEA];
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0019569 - L-arabinose catabolic process to
                     xylulose 5-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HFM8702865.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="ACHA1B_002117"
     CDS             complement(2393..3253)
                     /locus_tag="ACHA1B_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HFM8702866.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="ACHA1B_002118"
     CDS             complement(3258..3896)
                     /locus_tag="ACHA1B_002118"
                     /EC_number="4.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HFM8702867.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="ACHA1B_002119"
     CDS             complement(3911..4210)
                     /locus_tag="ACHA1B_002119"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM8702868.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="ACHA1B_002120"
     CDS             complement(4253..5737)
                     /locus_tag="ACHA1B_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HFM8702869.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="ACHA1B_002121"
     CDS             complement(5757..6218)
                     /locus_tag="ACHA1B_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM8702870.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="ACHA1B_002122"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="ACHA1B_002122"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030145 - manganese ion binding [Evidence
                     IEA];
                     GO_function: GO:0035460 - L-ascorbate 6-phosphate
                     lactonase activity [Evidence IEA];
                     GO_process: GO:0019854 - L-ascorbic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HFM8702871.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="ACHA1B_002123"
     CDS             7521..8291
                     /locus_tag="ACHA1B_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="HFM8702872.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="ACHA1B_002124"
     CDS             complement(8564..9391)
                     /locus_tag="ACHA1B_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8702873.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="ACHA1B_002125"
     CDS             9959..11194
                     /locus_tag="ACHA1B_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFM8702874.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="ACHA1B_002126"
     CDS             complement(12193..12453)
                     /locus_tag="ACHA1B_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HFM8702875.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="ACHA1B_002127"
     CDS             complement(12480..13781)
                     /locus_tag="ACHA1B_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFM8702876.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14073..14531)
                     /locus_tag="ACHA1B_002128"
     CDS             complement(14073..14531)
                     /locus_tag="ACHA1B_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HFM8702877.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14544..15875)
                     /locus_tag="ACHA1B_002129"
     CDS             complement(14544..15875)
                     /locus_tag="ACHA1B_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HFM8702878.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15886..17328)
                     /locus_tag="ACHA1B_002130"
     CDS             complement(15886..17328)
                     /locus_tag="ACHA1B_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFM8702879.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17315..>18062)
                     /locus_tag="ACHA1B_002131"
     CDS             complement(17315..>18062)
                     /locus_tag="ACHA1B_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HFM8702880.1"
                     /translation="NSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEHAVKLRK
                     EMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQEWNAQIQ
                     KIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHVDYFEPC
                     FDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGSSFVYPR
                     THQVEFLIHSAFAQKVKNDPLIELVTYEDI"
BASE COUNT         5756 a         3722 c         2792 g         5792 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataagttt tctaaatcat aggagcaaca aaaaaattcg ataattaaca aaaatcaaaa
    13981 tgattaaatc tagtgattga aacatatcat ttcaaaaaaa ttttgtaaat tcacccataa
    14041 atatcaccct atttaacttt tttcatcgta cactaaaatt caaaacaact atctttaatc
    14101 tttacttctt ggttttgttt taataaattt ccttcaaaaa tgcctggaga aactacaatg
    14161 atcaccgtat ctttttgtgc ttgctccaac ttcttcaaat ctataatagc taacagtgtc
    14221 ccttctttta cctcctggtt actttcaacc cgtatctgaa acggacttcc ttcgagttca
    14281 actgtatcta aacccatatg gatcagtatt tttctgccag attcactttc gatcgttatg
    14341 gcatgtcggg taggaaatat attatcgatt attcctttaa ctggcgcatg gatatatcca
    14401 tcatgattcg ttatagcgta tccaactcct atcatttttg aagaaaagac ctcgtctttt
    14461 actgctgtta atggaataat ttgaccacta gctacagctt ttagaatgtt tcttgtttta
    14521 aagaaatgca ctttttatca cctctacttt aatgctggcc aatatttttt gtttactttg
    14581 atcatttcat ctagtatttt ttttgcgact ctggcatttg gtacggtttg attcaatgta
    14641 aatgcttgta aagctttttg ataagaacct tcaaagtaag catctactag taacttctct
    14701 actgcaactt gtgcctccat caatccttta tgaaaatcac tgattggttt tcttagtgta
    14761 attggctcca caccagttgc accaacatat gccggtattt caacaactgc atctgaccgt
    14821 agattcggaa tcgccccttg attaggaacg attagcataa agcgacgacg atcatcattc
    14881 aacaaggaaa tagctatatc gacgatatat tgtccatgct ccccaaaatt aaagttcaat
    14941 acttcttcca caataccgcg gcgtatttta tcagccattt ctttggtatt tttctctcgt
    15001 ccatccatga ccatattagc acgtgtatac tctttgtcag tatgctcaac gaccatatca
    15061 ggatataagt aatactctaa gtaattattc gggatattac ttggaaaatt tttcgtgatg
    15121 actgacatca tttgaaaggt tttttgccaa gttttatctc ctatattaaa atcggcgact
    15181 tgcatttctt ttgttattag tttttcaata atctctggca taatttctcg ttgcaattct
    15241 ttatcataaa tcgatgtata ccagccaaag tggtttaaac cataatacgt aacgatccaa
    15301 ttcttacgat cataaccgta attcactgca atcgtttctt caattgaaat agtcatatca
    15361 caggcattaa tcatttttac attcggatat ttacgacgaa cagcttcaga aacgatcgac
    15421 tctggatttg tataattcaa aatccatgct ttgggggcat agtcttgtat atgatcgaca
    15481 atttccaata aacctttgat tgagcgcatc ccataagcaa atcctccgag tccacacgtt
    15541 tcttgtccta ctaatccatg tttaagtgga atcttttcgt ccttttctcg catctccaat
    15601 cctccaacac gaatttgtga gaaaacaaaa tcgcatcctg taaaagcaag ctttggatca
    15661 tccgttgcac gaatgcgaat atttgaaaaa ccttttcttt tcagcataaa tttaacaatc
    15721 aagtacatat ccatatttct ttcttcatca atatcatata aacgtatttc agataatggc
    15781 aaccgttttt cattgttcaa aatggcttga acgattcctg gtgtatacgt actcccgcct
    15841 ccagctatag tgataatctg ttttttcatc atcatctttt cctttctatt cttctaataa
    15901 tttattgaat tctgccataa cataagtcac ttctaagccg atgataattt gataattttt
    15961 ttcagttggt ttaatgatcc cgcttatccc taattgcttg attcgctgtt cctcgaccat
    16021 ggtgggatcc actacctcta cccgtaggcg tgtattacaa ctatagacat ccaggatatt
    16081 ggcttttcct ccaaacgctt gtagcatttt tgttgccata tattcataat ttttacttgc
    16141 taaccctaac tctgtttctt ctaaggttac ttcattgcca aactctgcct tagcttcacg
    16201 tcctaatgtc tgaatgtttc tcttattgat caaataataa aaagtaacgt aatacaaggc
    16261 aaaaaagaaa attccgattg gaagaatcaa aatagcattg gtagcgattc gaaaattgat
    16321 gagataatca acaatacatg ctccgaatgt aaaaccaatt cgtatattga ataagtaaca
    16381 gacaatccct gctaaaccgg caaaaagtgc atggatcacg tacaacatag gagaaagaaa
    16441 catgaaacta aattcaacag gctcagtgat atttgcaata aatgaagttc ctgcaccgct
    16501 tcccatgatt cctttgacca tctctttatt ttctttataa gctgctttat agatagctag
    16561 acatatagct ggtataccaa acatcattac tacaaaaaaa actgataaaa acagtccagc
    16621 ctgaggatct ccgttgataa agcgtgtcat ctctcctctg aaaacttcct tgctaggaga
    16681 tgtatagctt cctaaatcgt aataaatata cgtattcaac acatggtgca gtccaaaggg
    16741 gatcagcaaa cgattcaaaa acataaatat ccccacacct aatgctccca tatcaacgag
    16801 cagttttgca aaattatcaa tcccaatttg gatgagcggc cagataaagc ccaaaaaaac
    16861 agctgcgatt gtttgtagaa tcatcaccat agtcaatggg aatttttcgc ccgcaaaata
    16921 agaaaaaact actggtaatt tttgttcttt aaagcgatta tacgtccatg ccgctactaa
    16981 accggaaata attccaccaa aaatccccat attcacttct gggtccataa tttctaagcc
    17041 ttttttcaag gtagcaatcg ctaaaaaacc agtaagtgca ggtattcctt tgtccttatt
    17101 tttgacaaaa ccgattgcaa ctcctatagc aaataagata tccaagtttc caaaaacggc
    17161 atttccagct gcaccaatta ctgggatgtt cagcatatcg tcagctgata aacgcatgat
    17221 caatcccgct aatggcatcg ctgcaactgg aagtagcatc gctcttccaa gcttctgcac
    17281 atttgattta acattcattt ttattcctcc tctattaaat atcctcatat gttactaact
    17341 caatcaaagg atcatttttc actttttgag caaatgctga atgaattaaa aattcgactt
    17401 ggtgggtacg aggatacaca aaacttgaac catttaacaa ttcctgatcc aaatacgctg
    17461 cgtgacacat gacttcgatc gttttatctt ctctcaatat catgagtaaa cttgccaaat
    17521 attcttccac actcgtattg atttgtcgtt ttttttcatc agtttctcct acgacatcga
    17581 aacaaggctc aaaataatcg acatgacgaa cttcatcttt tcgttcaaag ttgctccgaa
    17641 ccggcaaatc atattttttt gctaatgtaa caactacctc ctgattttca tccaaagtat
    17701 gagtatgatg atgactgtct aaatgagttg gtatgatccc cgcatgataa attttttgaa
    17761 tctgagcatt ccattcctga tacagttgat ctttgtcaat gttaaatgga tgctgataat
    17821 aagataagga tctgaactct ccgctttcga taagagtatc gacagttttg aggagtggtt
    17881 tgccacacgt caatgttaaa tggactccta cacctagcct aggcatttcc tttcttagtt
    17941 tcacagcatg ctcgaaaccc ggcatatttg ccatcaatgt agttgatgtc aaaattcctc
    18001 gctgataagc atccataatc ccataattca caccatggct atagccaaaa tcatccgaat
    18061 ta
//
LOCUS       DAYYEF010000053        18061 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000053 DAYYEF010000000
VERSION     DAYYEF010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.055"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(71..1492)
                     /gene="tyrP"
                     /locus_tag="ACHA1B_002132"
     CDS             complement(71..1492)
                     /gene="tyrP"
                     /locus_tag="ACHA1B_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070908 - tyrosine:tyramine antiporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-tyramine antiporter"
                     /protein_id="HFM8702881.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="ACHA1B_002133"
     CDS             complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="ACHA1B_002133"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004837 - tyrosine decarboxylase activity
                     [Evidence IEA];
                     GO_process: GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HFM8702882.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3903..5159)
                     /gene="tyrS"
                     /locus_tag="ACHA1B_002134"
     CDS             complement(3903..5159)
                     /gene="tyrS"
                     /locus_tag="ACHA1B_002134"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000166 - nucleotide binding [Evidence
                     IEA];
                     GO_function: GO:0004831 - tyrosine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006437 - tyrosyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HFM8702883.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5271..5476)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5739..7040
                     /locus_tag="ACHA1B_002135"
     CDS             5739..7040
                     /locus_tag="ACHA1B_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HFM8702884.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7109..7708)
                     /locus_tag="ACHA1B_002136"
     CDS             complement(7109..7708)
                     /locus_tag="ACHA1B_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8702885.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7963..8844
                     /locus_tag="ACHA1B_002137"
     CDS             7963..8844
                     /locus_tag="ACHA1B_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HFM8702886.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8857..10467
                     /locus_tag="ACHA1B_002138"
     CDS             8857..10467
                     /locus_tag="ACHA1B_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8702887.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10544..11203)
                     /locus_tag="ACHA1B_002139"
     CDS             complement(10544..11203)
                     /locus_tag="ACHA1B_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFM8702888.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(11486..12151)
                     /locus_tag="ACHA1B_002140"
     CDS             complement(11486..12151)
                     /locus_tag="ACHA1B_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HFM8702889.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(12298..12903)
                     /gene="dhaL"
                     /locus_tag="ACHA1B_002141"
     CDS             complement(12298..12903)
                     /gene="dhaL"
                     /locus_tag="ACHA1B_002141"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="HFM8702890.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(12931..13941)
                     /gene="dhaK"
                     /locus_tag="ACHA1B_002142"
     CDS             complement(12931..13941)
                     /gene="dhaK"
                     /locus_tag="ACHA1B_002142"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004371 - glycerone kinase activity
                     [Evidence IEA];
                     GO_process: GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HFM8702891.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(13916..14311)
                     /gene="dhaM"
                     /locus_tag="ACHA1B_002143"
     CDS             complement(13916..14311)
                     /gene="dhaM"
                     /locus_tag="ACHA1B_002143"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase phosphoryl donor subunit
                     DhaM"
                     /protein_id="HFM8702892.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            14465..14785
                     /locus_tag="ACHA1B_002144"
     CDS             14465..14785
                     /locus_tag="ACHA1B_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HFM8702893.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(14897..15754)
                     /locus_tag="ACHA1B_002145"
     CDS             complement(14897..15754)
                     /locus_tag="ACHA1B_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFM8702894.1"
                     /translation="MKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTISSSG
                     AENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELEEALE
                     AAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQQAKE
                     FNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAASFQRI
                     KDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGVLVAA
                     AYGIIRKKK"
     gene            complement(15862..17166)
                     /locus_tag="ACHA1B_002146"
     CDS             complement(15862..17166)
                     /locus_tag="ACHA1B_002146"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFM8702895.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(17163..17672)
                     /locus_tag="ACHA1B_002147"
     CDS             complement(17163..17672)
                     /locus_tag="ACHA1B_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702896.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(17847..>18061)
                     /locus_tag="ACHA1B_002148"
     CDS             complement(17847..>18061)
                     /locus_tag="ACHA1B_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HFM8702897.1"
                     /translation="TQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFENDGD
                     EQRRRRQMYTAISRGMKSIVVLERAT"
BASE COUNT         5104 a         3716 c         3248 g         5993 t
ORIGIN      
        1 aaaaaactat tcacttggca ggacctccta ctaaatcagc gacaaaacgt cggctgaaag
       61 acttattttt ttatttttct tctaaacttt tttctacctc aatcccccaa gaatctttct
      121 tgaagtgatt gatgatcaat ggaataacga acatgaccac tgtgatagct gctactaata
      181 atgcatcact caatgtcgct gtacctaatg tagcaaatac gacaacgatg atagagaaga
      241 tcagcatgca gctgactacc caagctaatc cgtttccgtt tttaccaatt cggtaaggac
      301 gttcgaattc tggatgtttc ttacgcattt taagcaatga aacagcaatc aaaatgtaca
      361 cgatacaata aataacagtt gtagcatttg taagtgtcaa gaatacagca cttacgtcat
      421 ccattacacc ataaagcaaa gcaaataatg aaataacgat tgattgtgtt agaacgacat
      481 ttctagatac gccgtatttg ttttctttat ggaatccgaa ttttggtgga aggaatcctt
      541 cacgagctac ttggatgatt gtttttgatg gtccagtaac ccaagctgat aattgtaaaa
      601 gcacaccaat aaataccatg aagctgaaga tatttccgat cacttctggt aagcctagga
      661 tttgacagtc aatcaagata ggctgcgtga tatttgctaa ttccattttt ccatctggta
      721 cgacatttgc tacaagcatc gcattgatga cattcaataa aactaatccg atcaaagcga
      781 taaatacgcc ttttgtataa ttttttgttg cgtctttcaa acgaggcatg taaacagaac
      841 tcatttcgat cccaacaaaa ataaatgtga taccagctaa gtatttcaat gaatcaatat
      901 gttccaagtc agggaaagct tttgaccatg aaaagtcacc tagatagccg tttgagacta
      961 gtccgacttt gaaggctgcc aaaacaccta aaacgaacat gatgactact gggatatata
     1021 cccctagcca tacaccgatg ttcccgccga cttttgccat atcgaatttc aagttcaaga
     1081 tcgtgatgat ccagtagata actaaaatac aacctaaaac gaaccagtga ttattgccaa
     1141 gttctacatt accaaatgtg tttcctaaca atggtcctaa agtagaagcg accattacca
     1201 tacctgggaa catttgcacc cataatagcc atgcaacgac aaatccccat ttgctgccca
     1261 gtgctgtttt tacccataac tgaggaccgc cttcttgagg aagcatcgtg gaaagctcac
     1321 cggaaaccat tgatatcgga ccggcaaaaa acaaaactgc aaaaattgaa taaaaaatca
     1381 atgtccaacc gactgcggct aacgtaggaa tactccgaac cgttgcacac agtgccattg
     1441 tcagaccgat aaaggtccca agacccattt tacttacttc agatttactc accgttgaca
     1501 ctctccttga ttttttggat aaaataacgg tgtctttgaa gtagtttcag caataaacga
     1561 aacaattcag cgaatatttg aggggattct ttgagtttat tgcttgaagg gtttcttcaa
     1621 agacaacctc aaaacaaagg gatcgaagag cttaggtctc cccttgctct tcagatccaa
     1681 acatgcgtca gaaacagtta gtattcaagc tgttttctaa catgattacc ttgcttattt
     1741 tgcttcgctt gccaataatt ggtctgcgta gattttttcc aatttttctt gaagagctgc
     1801 tttgattttt tcagcatatt cttcaaagtg ttcttctttg ttcatgtatg gtgtcattac
     1861 gctggcacgc aatacagtta cttttccggc acggttccat tcttcatctg agaatcctag
     1921 ttggttcaca aattgtaatg ggctgttgcc atagtctggg atagcaaagt cagtatgtga
     1981 agttaagaac tcattaccgt aaatgcttcc tttcacgtat gaagaataat catatacgtc
     2041 atggttcaat ttattcattg caactaagtc atcgttgcct ttttctttga atacatagtc
     2101 taccatattg aaatctggat aagttaatgg atgaacttcg atttctttgt ctcctacttt
     2161 aaatgacaag tcattcaaga agttgtagaa acgatgtgca ccttcgattg atgcacccat
     2221 taatttacca tatcctgtga cattcaaagg taagacatgg tgtgctgccc aaacgctggc
     2281 tgctgttgcc cctgcttttg aaccttccaa gatataagcc ccaagtaatg ctgggatatc
     2341 tgcgcctttt tcaaatacat atgtcgcaaa gtaagagata acgtctctca tgcggatatc
     2401 tttgatgacg ataccaccgg cagaatatgg aacatagccc attttatgtg ggtcaatcgt
     2461 tacagattct gcttcttcga ttgctttata tgcactgtgt acttcttcta agatataatc
     2521 tttgttttct gtaaagacat tgtatttgta atgaacatct tttaaatctt caaatggaat
     2581 gaagttgttg tcttcgtcta agaaaatcgc acggccgtat ccgccataag cagcatctac
     2641 gtgtaagtag aagtaaatac cgtctttttc taatacgcga cgcaatgcaa cgattttatc
     2701 gataccgtcg attgctcctt cttctgttga tcctacaaca ccgactacac ctaggattgg
     2761 tgttttttca gctgctagac cacgaacgat tttttcaagt tcgttgatgt ccatgcgata
     2821 gttgtggtca actggcactg gaatcacttg gtctaaaccg ataccgatga tgtcggcagc
     2881 ttttagccat gaatagtgtt tagtttgtgg aaccaaccat tttcctaatt tttctaaatg
     2941 ttttccgcta cgtgctgagt gagctttgat ttcgtcgatt ttttctggga cgctgtctaa
     3001 cagattcatg atttcttctg ttgacaagtt cattaattcc caatcgcttt ttccagcaac
     3061 tagttcaggt gtcacttctt tcattgcaag cggcaatgat ttgatgttgc gggcatacca
     3121 aagtccttct aagtttgcta aagaaccatc agcaacgatg tggccccagc catctttata
     3181 gctcattaat tttgcaaatt ccattcctac ttcttcttcc atttggcttg ttgcaggaga
     3241 agattcatag gcaacgttat taccattcca tagcatagca aaattgtacg ctagtaaaga
     3301 tggcatcaat gtttcagagt tcatatgacc ccagtaacgt ccggcattat gccaaggaac
     3361 ggaatgggta cgcatccgcg ctgaaatttc tgatagaaca tcctttgttt tattcacagt
     3421 gtgttcaaaa ctagcactgc ttttttcttc tggcgtaata ataggcatgt cttgaggcat
     3481 gtagttttga cgccagccta aatgttcatc caccaattca ttcaacaaag ctttatagat
     3541 ttggccgttc tcagctttgt ccccaatgaa tagggcattt aggtttagat ctttcgacaa
     3601 tgattcactc atagtgaaac cctcctaaaa aaatatttaa attttgtcga gccctacatt
     3661 acacctgttc ttctattctg taaactaagt tttggcctga tttttaatca tattttaata
     3721 tgtatcaatt atccgaattg ttcacacttt tgaaataatt aaaaaaaacg agggaattta
     3781 caaatgtaaa ctccctcgca aagattgtat taacgacaac cagcgttcta ttttaggatg
     3841 ggtttcaaaa ttggaatgtt gtaatagtat ttcccttttt caaggtaaaa acttactaaa
     3901 ttctaatcaa ttactttggc caaaaagtaa tttttcttac cttttcgaat aaccacaaac
     3961 ttaccatcga attcatcgga tggatttatg acaaaattta aatcggtaac gcggtcaccg
     4021 ttaatactta tagctccgtt tgaaacatct tcacgtgctt gacgtttaga tggttcaatt
     4081 tttgtggaaa caagcagttc cacgatattt tcaggtgtgc ttgaaatttc aacgttcggc
     4141 attttaccga atccttgcgc gatttcttcc gcatttagtt ctttaatatt tccagagaac
     4201 aatgcttgcg ttattttttg cgcttctttc aagtcttctt cactatgcac aaatcttgta
     4261 acttcttctg ccaaacggcg ttgtgcttca cgtttctcag gttctgtctc tacttttttc
     4321 gctaagtctt cgatttcttc ttgagacaag aaagtaaaga atttcaagta tttcactaca
     4381 tcgcgatcat cttgattcaa ccagaattgg tagaactcaa atggtgaagt tttcttcgga
     4441 tcaagccaaa cggcaccgcc tgcagttttt ccgaatttcg ttccgtcagc cttcagcatc
     4501 aatgggatcg ttaaaccgaa cgcttctgct tctggtcctt ctaattttcg gattaggtct
     4561 aatccagctg tgatatttcc ccattggtct gctccaccga tttgcaattg cacatcgtat
     4621 gttttatgca gatgcaaaaa gtcgatagat tgcaggattt ggtaagtaaa ctctgtaaat
     4681 gagattccta cttccaaacg gctggcaacg atatcttttg ctaacatcgt gttgatgttg
     4741 aagtttttac cgtagtctct caaaaattca agtaaagaga tttttgacaa ccagtcgtag
     4801 ttgttcacaa atgtgatatt tgcatcttta ccaaacaatt ttctcatttg attggaaagt
     4861 gcgtccacgt tatgttgcac ttgttccatc gtttgcaaca cacgttctgt tttgcggccg
     4921 cttgggtcgc cgatcgttcc tgttccgccg ccaatcagaa tatatggatg atggcctgcc
     4981 aattggaatc ttttcatcat cataaatgga atcaaatgtc cgatatgcat cgaatcacca
     5041 gttggatcaa cgccgcaata aagtgaaatg ctcttttctt caacgagctc gcgaagtctt
     5101 tcttcgtttg tttgctgatt aatggcgtcg cgccaagtta attcatcaat aatattcatt
     5161 ttactgacct ccgtgtagtt tttttatgaa agcaggaacc tgctagcatg tgtaattaat
     5221 tatttcttca ggataggata ggaaataaaa aaagtccctt ggcatataag ccaagggacg
     5281 aaatctcgcg gtaccaccca atttgtatgt ctagatatcc aacatacctc tcgaacattt
     5341 aacgctgtcg cgtggcaatc actgccaaag actcctgaaa tgtaattcgc tttaaagcat
     5401 gtactggttt gcagcgacca ccagctttct gaaacattgg ctttaacaac tacttcgttt
     5461 cgatcttcgt cttgttatta ttaatatgtg tctatcatag agcgcaactt tttctttgtc
     5521 aacagaaaaa ggatattttt tttaaattcc tcattttttc ttttttgaat ccgctctaat
     5581 tccgaacatt ttattttcaa ttattgttaa aagaaataac tttttctgta ttttttctgc
     5641 aatttatcga gaagtcactt tactttgcct cttattcttt cttcgttaca ataaggaatg
     5701 ggacaagtaa aaaaatgaaa aagcaaggga cgaggtatat ggaaaaaaag caaaaaatta
     5761 ttttaggagc cacttctgct ttaactatcg ttattttaat tctaagtttg ttttttgtca
     5821 tccgatcatc tacaaaaaaa gaaccaatca ttcctgaaaa aaaaataaca gaaaaagcaa
     5881 aagaaccgac agatgataag caacaactag ttactcaagc aaaaaatctg gctcaaagct
     5941 acgattatga ccaagcgatt gcgttattgg aaaaagatag taagaacgga tctactgaaa
     6001 cacaacagct tcttcaaaca ctaaaaaagg agaaagaaca actgatcgac tggtctgatc
     6061 ctactcagat ctctcatgtc tttttccaca gcttgatcgt ggacccgcaa aaagccttcc
     6121 actctcaaca ggcacaagga tacaaagatt atatggtgac tgttgaagaa ttcaaccgtt
     6181 cgatcgaaca actttatcaa aatgattttg ttttagttaa tttgaatgat ttgatccaaa
     6241 aagacgaaca aggaaatctt tcctttaacg ggcttgcgct acctgaagga aaaaaaccat
     6301 tggttctttc acaagatgat gtcagctatt atgaatatat ggataattcc ggttttccta
     6361 gccgattggt cgtatcaaat aacaatgaaa tcaaaaatgt ctataaagag aaagataaag
     6421 aagaaatcgg tgactttgac atggttcctc tgatcgatgc ctttgtcaag aaacatcctg
     6481 atttttctta tcgaggcgca aaaggtacct tggccctgac aggttacaac ggagttttag
     6541 gttatcgaac atcaaaatct caatatggag acaatgaaaa aacaaaaaaa gagattaaag
     6601 aagctaaaaa agtggcggaa cagttgaaga aagacggctg gagctttgct tcccatacat
     6661 ggggtcactt gaatatgact caagcttcac tagaagatgt aaaaaaagac aatgaattgt
     6721 ggcagcaaga agttgcacct atcctaggaa aaacaaatat tctgatttat ccatttggtg
     6781 cagacatcag cgactggcag ccttattcag cagaaaatca aaaatttgct tacttgaaga
     6841 gtcaaggttt cgatattttc tgtaatgtcg atgcttctac accagcttgg ggacaattag
     6901 gtacggattt ctatcgaaat gctcggatca atatcgatgg cattcgtttt caatctgatt
     6961 tagacggaaa aaatcctatt cttgatccat tcatcaatgt ccatgatgtc tatgacaaag
     7021 aagcacgcga atctgcttga ttttacgtca tttatgaacc aaaaaagccg aactgacatt
     7081 ttatcgtcag tttcggcttt tttatgcttt atttcttctt cggtgcgatt cccttgatca
     7141 ggacttctgt ccattctgct gtatatggaa gcagttttgc gtatatctcc ggcttagaaa
     7201 ttccttctac cattgcttga aaatagagga tcaagaactc atccgaatat ttcaaatcca
     7261 cttttccttc tttccgccct cgatggaaaa gatcaagcat gatactgaaa ctttcttgcg
     7321 tatacgcatc catcgcgtca gaaaattctt ttttttcttt ttttgtatag tatgtcatca
     7381 aatcgatata aaattgtttg ttcactcgat tgagataacg gattttgttt tcactcatgg
     7441 caatcagtgt ttcttcaaat ggaagatttt ccgcaatcaa cgctttcgct tcttgcccta
     7501 aatcattcat aaatgcaaaa aatacttcat aaatcagccc ttccttgctg ccaaaatatt
     7561 taaaaatcgt cgctttactt acctgagcgt tctcagctac cttatccatt gtcactccag
     7621 cggttcctat gtctgtgttc atcaagtcaa aagctgcttg taaaatctct ttctttttct
     7681 cttgtgctct cttttcaaaa ccgttcattt gtagagcctc ccgtaatttt aaacttttat
     7741 aatatatata gttcaaattt attctgaggt ttattataac tatctattga gaaagtatca
     7801 agctagcaat tccttgttta tgaattcatt gacagaaatt tataaaaaga atattatgta
     7861 ctaaaataat aaaaaaaagt tttataaaaa ggtataaaac ctttttatta aactatttaa
     7921 tcttgtttag tatatatttt tagaaaaagg agtggggttt ttatggcaga aatcgtcaaa
     7981 gtcacacatt tgaaaaagag ctttggtcgt ttcgaagctt taaaagatgt ctctttcacc
     8041 gtacattcag gtgaagtcgt tggatttatc ggaccaaatg gttctggaaa atccacgacg
     8101 attcggacac ttttagggat tataaaaaaa gacggcggaa cggcaacgat ttttgggcaa
     8161 gatgtatggg aagatagttt atctatccat gaacgtcttt cttatgttcc aggcgatatc
     8221 tctttgtggg gaaatttgac tggaggagcg atcatcgatc tcttcatgaa gcttcatgga
     8281 aaagggagtg ctcaaaaaaa agatgaactg attcaacgtt tctctcttga tcctaagaaa
     8341 aaagcaaaaa actattcaaa aggaaatcgc caaaaagtgg gcttgattgc tgctttggct
     8401 gttgattcgg atctctattt atttgatgag cctacttctg gtttagatcc tttgatggaa
     8461 acgattttcc aagaagaagt tgaaaaattg aaagaacagg gcaaatccat cctactttct
     8521 tctcatattc tcagtgaagt cgagcgacta gcggataaag tcgtgatcat acgcgaagga
     8581 acactcgatg aagaaggaac actcgatgaa ttgcgtcatt tgactcgttc gaccatcact
     8641 atagaaacag aagcagagaa tagtcactta gcacaattga acggtgtcca tgactttgtg
     8701 caaaaaggtc acctcgctca atttgctgct gataacgaag ctttcgatgt gattttagct
     8761 gaagcgtcca aattaggtgt gaaaaaattt gaatctattc caccgactct tgaggattta
     8821 ttcatgagac attatgaagg atgaggagga agcgaaatga ctgataaatt ttcacgctgg
     8881 tccacccttt tttctcaaaa ccttagccgt gactggaaaa agatcctgat atggctagtc
     8941 ggtgtcactg ctttttctgg tggttttgtc cctgcgtttg aagaattgac ttccggacaa
     9001 ggattagctg gattatacga aaccttgcaa aacccggcaa tgattgcaat ggtcggacca
     9061 actccagctt cgaatgctgc tgagtatact ttaggagcga tgtatgcaaa tgaaatgttg
     9121 cttttttgca gtttgtttgc tgctgtgatc tctgttttac acgtggtgag ccaaacgaga
     9181 aaaaaagaag aacttggtct gattgaactt attcgttcct ttcgagtcgg acgtcaagca
     9241 aactctttag ctgtcatcgc tgaaagtatt ctgatcaatt tgcttttagc aatatcgatc
     9301 agctgtacga tgattttttt ccaagcggat tcgatcactg cagaaggtgc ttggcttttt
     9361 gggctatctg taggtagtat ggggattttg gggagtgccg ttgcactgtt tgctgcacaa
     9421 ctgatgccaa gttcagccag ttcgaatggt ctgtctttag cgtttttagg tggactttac
     9481 cttctacgag caataacaga tgtagctgat tcctcccttt cgatgtggaa tcctttaggc
     9541 tggtcttatt tgacctatcc atttacaact aacaactgga ttcctttgct ttatttgttt
     9601 ttgttcagtc taatcttgat aatcagttca tttgttttag aggaacatcg agatttgaac
     9661 accggctata tccccgaacg tgaaggaaaa ccgtatgcta aacgttctct tttatccttg
     9721 cgtggtttat tattctatct aaataaaggg atgacaatca gttggcttat cacttttggt
     9781 ttgatggggg cggcatacgg ctctatctac gggaatatgc aacagttttt agaaagtaac
     9841 gacttaatga aacagatgtt tatccaatct ggcgtctcaa ttgaaaaaaa ctttacaagc
     9901 acgatcatgg tagtcttgat ttgtctagct gctattttac caattgctag catcaatcgt
     9961 ttatttacag aagaaaccca cggacgtatg aatcagctgt tcgcaacaaa aatttctagg
    10021 aaccaacttt attggaccaa tatgttacta gctattctat ttgctatatt ggcaatcctg
    10081 attagttctg gtgcactagg gctttctgct ttggcttcga tgaaggatgc gaaagacatg
    10141 gatctattga tgtttcttaa agccgggttc aatttcctgc ctgccgtttt agtgtttatc
    10201 ggaattagtg gctttctatt cggatggctt cctcgaatcg gtaaacttgc ttatatctac
    10261 ttagcttact cctttgcact caattacttt ggcggaattt tggatttacc agaatggttt
    10321 tccaaaacag ctgtccctag ctgggttcca cggatgccaa acgattcttt tgatctttcc
    10381 gtgttcctta cgttatcatg tatcagcctt gcactgttcg tccttggttc tattggttat
    10441 aggcgaagag acttactaga aggataataa aaaagcatgt acaatttcat gctagcctcc
    10501 aaatctgggt caaaaatcca acatttggag gtcatttttt tatttacaag tcttctaact
    10561 gctctttatc aatgatccag acttctcgat tctttctttt tacataacca ttctcctcta
    10621 ataatttaaa ttttctagat aaagtttcgg gggtcgtacc gataaatgca gcaagttctt
    10681 tcattttcat tggcaggaaa aagtgatcct tccctgtcgc tttagctaag tcaagcagat
    10741 agacagcgac tcgttcttct actttttcca tcatcaaaaa agttgtctgc tgctgtactt
    10801 ttgttaattt ctcaacgttg attgctaaaa gtttcagact aagggcggga taatgcagta
    10861 agagttccga gaaatctttt tgtctcaata tgcaaatttc cgttttttct agtgcttcgc
    10921 caaataaaga ctcatttgga acgcctagca actggctctc tccctcatat ccgcccggct
    10981 ctattactcg taaaagctgt tcctttccgc tagcagataa ttgatacact ttcatactgc
    11041 cggaggccac gatcactaat tgaggttctc cattcggcgc aagaatctgt tctccttttt
    11101 ccacatagtg atgtttgaca agtgcgtgta ctttttcttg atcttgctgt actaagtgat
    11161 tgaacaaagg aacaaatgaa acacataaat gatcatgact cataatctct cctccttcta
    11221 aacagctatt tctaataaag aaacataact tcccttattc caactgataa ttttctttta
    11281 tcatagcata aacgtcaagc gaaccagata ccagcaaata gagtggattt ctttttgtcc
    11341 cttgctttat tttccttctt ttgagacctt aagtaattga ttcctatcaa ttttttaaat
    11401 atttactttt tgaataatca aaaacaaacc ttcactcgca agccgagagt aaggtttgtt
    11461 tttcgcattg cttatttcgt gttgtctatt gaaatttttc cgcacctagc ttttgatata
    11521 gtggtgctag ttcttgtaag gtttcagcgg ttatttgctc aacgtgttcg atttcttgcg
    11581 gatagaagaa tagtttaccc atttgaaagg ttcggtctct catcgctttt ttcaactctt
    11641 cttgtttctt tgtatcggac aaatagtcag acaaagctaa gtggtcgtca agttcatgtt
    11701 ctggttgcgg ccatatgtaa taatccttga tatcgactgt tttgctccac tctttcagta
    11761 tcgcaagcaa ctggttatac gctgcaatgc taccatatcg ttcttcgctt ttataatgtt
    11821 ggtacatcaa atagatttgg tattgttttt gattcaacaa aactgctaga caggcattct
    11881 cgtcttgacg agattcgctt cggtacgcgc tccaaaaatg actgcgtaaa ttccagccat
    11941 tcgtccagct ttcgatttta ggtttgctca tgccgtacat atcaggcaaa agtgcagctg
    12001 tctggagctg aatctctttc catttttgcc agtgttcttt atattctttc ttgatttgtt
    12061 caatcttatc tgttggatgg ctctctttga gctgtttgaa tgcgtagatt ggtcgatcaa
    12121 acaactgata atctgatttt ccaagttcca ttgtttcgcc tctttccgtt atcttttgta
    12181 ttctacctga attttgcgat atggacaaat agaggttgtg aaaaagctgt tctgcatcaa
    12241 gtcataagaa cagccaaaca aaaaactgcg atgagcatca ccgcagtttt attgaactta
    12301 aggttgattg atcacatcta aaagcgttga aaataaaatg gcactagaag cagctcctgg
    12361 gtcgatatgt ccgattgcac gctctcctag ataggaagct cgtccttttt tagctaccaa
    12421 gactttggtg tgttcttttg cctggtcaat gatttctttt gttaaattcc ctgccttcaa
    12481 tgcctctgtg actggcagcc aaacatctaa catcgtttta tcgtcagctt ctgcctttcc
    12541 tcggctttga atacccgctg ttccctgctc gatcacttcg cctaattttt cttgagaatc
    12601 aatagaatcg acctcttttg tcgctttcat catgttcatg aatgcagatc cgtataacgg
    12661 accagaagcc ccaccgactt tcgatatcat cgccatagag aatactttga atgtatcgct
    12721 gattgtttca ggatgatcgg cttgaaaagc ttcttcataa gctgaaaccc ctcttcccat
    12781 gttatttcca tggtctccat cgccaatcgg ggtatctaga tcactgagat attgtttgtt
    12841 ctgattgatt gcctctgcaa attgcgtgag ccattcttgg atttcttgaa cggttagttt
    12901 catattatca cccttttatc ttgagatttt ttaccatgaa atcgtctgta cattgctttc
    12961 taaagaatct ttccattgtg tctccgtcaa gtcgatcagt gttagagaaa gaccttgcat
    13021 atctagtgag gtcataaaat taccgacttt tcggaaaact acattgacgc ctctttcttc
    13081 caacagagct aaaacatcat tcatgaacac gaactgttcc atcaaaggcg tcccgcccat
    13141 tccgttgact agtacacctg cttcttttgg taaattcgag taatcatcta aaatcttagt
    13201 aacaagttcc tttgccagta ctttagaagg ctgcatcttt tctcgacgat agcctggctc
    13261 accgtggata ccaacaccat actcgatctc atcttctcct agttcgaatc ctggtttccc
    13321 tacttctggt acagttgctg ctcgaagcgc tagaccgatc gtcttagttg cctgtacgac
    13381 cttttctccc agttctttca actcagctag ggaagcaccg tttcttgctg catcgcccac
    13441 gattttgtgt acaaggacag tacctgcaac tccgcgtttt ccagcagtat acgtactatt
    13501 ttcaacggcg atatcatcat ctacgatcac actttctact tcaatatcgt ccatagcagc
    13561 taattccttt gccatatcga agttcaatgc atcccctgta taattcttaa cgatcagcaa
    13621 aactcctttt ccactatcgg cttccttaat agccgtctga atctgatctg gagttggaga
    13681 agtaaacaca tcaccaagca ccgctgcact taacatccct tcccctacaa acccggcatg
    13741 ggatggttca tgtccgcttc ctccaccaga aaccaaacca acttgttccg ctttctgatt
    13801 cttggctaca acacgggaag attctacacg atgaacaagt tctggatagc tttttactaa
    13861 tccttccagc atttcttcga caatattgct tggatcattc atgatttttt tcaatttatt
    13921 cccatccttt ctttccggca ttttgtgctt ctgttaagat ttgctgagta tcatctgtta
    13981 taccggcagt gatggctgct gcaaaagctc cttccactaa aggcgcatcc accagatgat
    14041 aacgttgctg ctgctcttct tccaacatgt cttttgccag ttccgagttc aataccgcgc
    14101 taccgatatc cgcaaaaaca aaataactag ctgcatcgct tgattcattg actgcttcta
    14161 cgattttcat cgggtctgat ccgatctcgc catttattcc gccgagagaa aaaatttgca
    14221 cctcttcgga tttttgcatc tgctcaatca tttctttaat accatctgtt actttttgac
    14281 tatgagaaat aagcaaaata ctttttttca caagaatctt cctttctttt acatagttgc
    14341 taacgattgg tttcgctttc attaatgaac aattcaagta tataataaat ttctaatttt
    14401 gggaaaatat gtgtagtgct tcttgaagtt tgttatactt taattaaaag agaggagtga
    14461 tcgaatgatt acaacaacaa cgaacagtgt agagggaaaa gccgtagtag cttataaagg
    14521 gatcgttttt ggtgaggtca ttactgggat ccatgcattt aaagacttgg aggcggggtt
    14581 gcgaaatatc tttggcggcc gctcaaaaag ctatgaaaac gaactaatgg gtgcaagaga
    14641 agaagcactt gccgaaatgg ccgaacgtgc aaaagcatta ggagctgatg cgatcattgg
    14701 cgtaaaaatg gactatgaag tattaggcag cgacaatggc atgctgatgg tcacatgtag
    14761 tggaacagct gtctccacga gataagtagg ggacatctgt tttaataact aaagagagat
    14821 gggacatgta gtggcactca agaattagat ttttcagtct aacttcgagg tactctacct
    14881 tcccatcctc tcttttttat ttctttttgc ggatgattcc gtaagctgct gcgactaaca
    14941 cacccgcccc tgctaaggaa taactgacag aagctgtttt ttcatttgtt tttggcaaag
    15001 tctgacttgt tgatttggat ggctctgtcg tttgctgaac tgtttctgtc gtgcttccag
    15061 aggtcactga tttttctcct gccgaatgca aaatatcttt tattcgttgg aaactagctg
    15121 ctaagtcagc tttttttgct tcaaaatcat tagcaactgt ttgtgcttcg ctgatctttc
    15181 cgtggattgc ttgactggcc gctgtgatat ccgcttgagt ttgacttagc tttccagaag
    15241 ctgtttgagc aacctgattt aattgctgat tgaattcttt tgcttgttgg atcttcccgt
    15301 caagatctgt ttggacagct tccgcttttg ctttcgcttc ggcaagcttt ttctcaagtt
    15361 gtgcacggtc atttcccact ttatttttaa gatcagctaa atcttgatcg attgctgctt
    15421 ggtcttcttt caatttgttt tttgcagctt ctaatgcttc ttcgagttct tttcttttat
    15481 tttccaagtc ttgcaaatga tcgatttggt cagaagaggt agaactattt attgatgtat
    15541 cttctgaaga tgaaatcgtt tctcctgaat tatctgtcgg tacattggaa gtcatttctg
    15601 tttccgaggc accgttttca gcaccagaag agcttatggt tgttgaaggt tctgtttgag
    15661 caggttcaga agtttccgca aaagctgtct gtcccaataa gaaaatactg gaaacagcaa
    15721 ttggccagat taacggcttc attctttttt tcatcacttt tcccatcctt actacttttt
    15781 aactaatttc ttattataag caaaaatgtt tggaagaacc ataaacacaa caggctgttt
    15841 gtctaaaaaa cggtgcatct tttatttttt tgtacgttcc gggcttttcc atgtcccgct
    15901 tccataacct aaaatcgttt tgactgctgg aatgaaagtc gtcacgatcg ttatcgcgtt
    15961 cactatccag aacaaaagca tatatagtgg tgcgaaaaga aggtatttca attttcttcg
    16021 tcgatcatct acaatcagcg aagctagcaa ctggaaaaat cctgcgacca tttcaaagca
    16081 gatgaacaca aaactgaatg taaaagtaat ataaatctgt tcgtagtttc cttgatatac
    16141 ataatgcccg attaatccag caaaaagaac tacggaaata caaaagaata ttgaccagac
    16201 aatactcaat gtttgatcaa tgaagatgat cgttcttcca atatgtttaa aaggatggag
    16261 catcactttt ttgaaattcg tcagccagac ttctgttcca ccttttgccc aacgttttct
    16321 gtgtcgatat agcatcttca acgtcacagg tacttccatg aaaaagataa tctcaggagc
    16381 aaaaacagat aaccagtcat ttaactgatg atcccaagca atactgatgt cttctgtcgc
    16441 tcgatcttgt ctgaatccgc ccacatcgat caaggcttct tttcgataca tcgtatttgc
    16501 tccactgtac gcataaagac caccgaaaac agctgactgt gttcgtttaa tgatgcccac
    16561 gatacttgag aattcaaccg tttgagattt tgcaatcaat ttggtacgat tttggacatc
    16621 catatttgca gtgaccgcag caatatgtct tgcaccaggg cgaatgaaat aattcacata
    16681 cctaatcagt gcatctggct ccggtaccgt gtctgcatca ttgcttaaaa tcaatttccc
    16741 ttttgcaaag gcaagtccga tattaaacgc gtgggctttt cctttatttt tttcgatccg
    16801 aaccacacga agattagcgt attttttcat cagtctagct aatatttctg gtgtttggtc
    16861 cgttgaacca tcgtctgtca ctaatacctc atagttgtga taattcaatt tcgtcatcaa
    16921 atactcgatt gtatattcga tcacaatttc ttcattatgg gctggcacca tgatcgtgat
    16981 gaacggttcg acactcaagg gaacatctac ccattctttt tgcttatgtt tgtataaaaa
    17041 cacataacac cagacaccaa taaaccatac aaatccgcct aaaatcggat aagaaacgag
    17101 aaaaaaatac ataatagaca aacaagtatc taagaataaa ttacctgtat gggtgattga
    17161 gatcatttca gttccacccc attttcttta tacaaatctg caatgaatgt cgtatctaga
    17221 tttttctctt cggagacaga ataaaaacgg accgtttctc tctcttcttt tgttccaaaa
    17281 cgttccgtat acacttcttc aagtaattct tgtctttttt tcaatttttc atcttcatat
    17341 tcaaaagatt tatttacttt tttgtataga tttcgattgt tccacctagt caatacaaat
    17401 gaggtaatca ggaaactgaa aaaaatcaat acaaaaaagc cgattaagaa atacagcatt
    17461 ttcttttctg ataaaaaagc gtacaaggaa aaatccttgg ctctttctgg tctcgttaat
    17521 gggaaaaaga cccatataaa aggaagaaca acgatcatcc atcctaaaag agccactaac
    17581 gtttgccaaa tctttaacca gtaattacct tttgaaaaat acttatcttt caccaaaatt
    17641 gatgcaactt cttctcttgt tacttttttc atatcctcac ctcacgtttt tttgttacga
    17701 cgtaggagtt taccatacat ttcatttctt ttcacataaa gtgttcctaa atttttccta
    17761 agaaaaagaa caaaacattt ctcatcagca aatgaaaaat attttgttct ttttatcagt
    17821 tgttcttttt attttttatc tcttaattat gttgctcttt ccaatacgac aatgcttttc
    17881 attcctctag atatcgccgt gtacatttgt ctgcgtcttc tttgctcatc tccatcgttt
    17941 tcaaatggat ataagattac atgatcaaat tccagtcctt ttgctagact caaaggaatg
    18001 atttggcagt tttctaatcc atatgaattt tttttaatcg attcttgtag cgtttgggtt
    18061 t
//
LOCUS       DAYYEF010000054        18015 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000054 DAYYEF010000000
VERSION     DAYYEF010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18015
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.056"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            289..606
                     /locus_tag="ACHA1B_002149"
     CDS             289..606
                     /locus_tag="ACHA1B_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFM8702898.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(697..1062)
                     /locus_tag="ACHA1B_002150"
     CDS             complement(697..1062)
                     /locus_tag="ACHA1B_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702899.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1270..1752
                     /locus_tag="ACHA1B_002151"
     CDS             1270..1752
                     /locus_tag="ACHA1B_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702900.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1949..2839
                     /locus_tag="ACHA1B_002152"
     CDS             1949..2839
                     /locus_tag="ACHA1B_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042301 - phosphate ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HFM8702901.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            3165..5639
                     /locus_tag="ACHA1B_002153"
     CDS             3165..5639
                     /locus_tag="ACHA1B_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFM8702902.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLLKRRNNTVAMTGDGVNDI
                     LAMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLV
                     KNIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNV
                     MEKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKF
                     RSQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLF
                     ERKNEKEQKPFSRVVKKFLSIFKREN"
     gene            complement(5742..7478)
                     /locus_tag="ACHA1B_002154"
     CDS             complement(5742..7478)
                     /locus_tag="ACHA1B_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM8702903.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(7475..8179)
                     /locus_tag="ACHA1B_002155"
     CDS             complement(7475..8179)
                     /locus_tag="ACHA1B_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM8702904.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            8310..8813
                     /locus_tag="ACHA1B_002156"
     CDS             8310..8813
                     /locus_tag="ACHA1B_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HFM8702905.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            8773..9111
                     /locus_tag="ACHA1B_002157"
     CDS             8773..9111
                     /locus_tag="ACHA1B_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HFM8702906.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            9132..10550
                     /gene="ffh"
                     /locus_tag="ACHA1B_002158"
     CDS             9132..10550
                     /gene="ffh"
                     /locus_tag="ACHA1B_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0048501 - signal recognition particle,
                     plasma membrane targeting [Evidence IEA];
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA];
                     GO_function: GO:0005048 - signal sequence binding
                     [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_process: GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HFM8702907.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            10662..11240
                     /locus_tag="ACHA1B_002159"
     CDS             10662..11240
                     /locus_tag="ACHA1B_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HFM8702908.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            11244..11765
                     /locus_tag="ACHA1B_002160"
     CDS             11244..11765
                     /locus_tag="ACHA1B_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HFM8702909.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(11844..12398)
                     /locus_tag="ACHA1B_002161"
     CDS             complement(11844..12398)
                     /locus_tag="ACHA1B_002161"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008752 - FMN reductase (NAD(P)H) activity
                     [Evidence IEA];
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0052873 - FMN reductase (NADPH) activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HFM8702910.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            12651..12926
                     /gene="rpsP"
                     /locus_tag="ACHA1B_002162"
     CDS             12651..12926
                     /gene="rpsP"
                     /locus_tag="ACHA1B_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA];
                     GO_component: GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HFM8702911.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            12938..13189
                     /locus_tag="ACHA1B_002163"
     CDS             12938..13189
                     /locus_tag="ACHA1B_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HFM8702912.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            13313..14104
                     /locus_tag="ACHA1B_002164"
     CDS             13313..14104
                     /locus_tag="ACHA1B_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702913.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            14274..14795
                     /gene="rimM"
                     /locus_tag="ACHA1B_002165"
     CDS             14274..14795
                     /gene="rimM"
                     /locus_tag="ACHA1B_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Essential for efficient processing of 16S rRNA;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0043022 - ribosome binding [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HFM8702914.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14785..15546
                     /gene="trmD"
                     /locus_tag="ACHA1B_002166"
     CDS             14785..15546
                     /gene="trmD"
                     /locus_tag="ACHA1B_002166"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0052906 - tRNA
                     (guanine(37)-N1)-methyltransferase activity [Evidence
                     IEA];
                     GO_process: GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HFM8702915.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15682..16029
                     /gene="rplS"
                     /locus_tag="ACHA1B_002167"
     CDS             15682..16029
                     /gene="rplS"
                     /locus_tag="ACHA1B_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0000311 - plastid large ribosomal subunit
                     [Evidence IEA];
                     GO_component: GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HFM8702916.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            16390..17058
                     /locus_tag="ACHA1B_002168"
     CDS             16390..17058
                     /locus_tag="ACHA1B_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702917.1"
                     /translation="MGKDKRIVWKDQSDLKIILTISQFIETYEIKSSREYQKQLSKNP
                     NSAPSMWFIINKYGSWNNLLNSIGIDNSGSKKWAKMETDELIKVAQIFIDSEKIKSQR
                     VYEKKSVGKDVPCISTLKNRLGDIRFLFKKEVNKGLTNFEILLELKNEIIRLNMEDDL
                     SMTKFQNYSKSKHLPSVYTIMRRTNKTWEELMSEIGYDYRKIKIKKQRNNLRCRSKNN
                     MSKT"
BASE COUNT         6093 a         3101 c         3619 g         5202 t
ORIGIN      
        1 agattacaaa tagtatcgta tttcgcaatc ttaaaattat cttcttactg tgaataagat
       61 aataaaattt gtatttgtcc tttttaggta acttatttta atctatatac ctttctggat
      121 caacgaaagt atactttata tagtcataac gccgatggta actatgcact gtaacgataa
      181 tgctgctaaa atatcttttt acgaaaaaca tcacaaggaa aaacttaact atggtattat
      241 ctaaacataa ttttttcggt atttaatatt taattaggag gtaatatttt gcttttttat
      301 agtaatttta tcttaatagt agcgatatta ttacttctga atatatggat ttttgatagg
      361 agtagaaatg caagtatagg ttttagaact aaacgaagtc tgtcttctaa aaaaaattgg
      421 gtatactcac aaactatttt ttatggagga attgttttaa ttagtttact ttcttcaaca
      481 ctttattctt tgaatattat agatgtttcc acctcaaatt caatatctat tattggaatc
      541 attattgctg caattattac acaactgttt ttagtgtttg gagagaagaa aagaagtaaa
      601 aaatagaaaa actagtgata gttttggtga tataagaaaa acatatatgt ataaaaagaa
      661 gaaagtagct tctctttgta catatatggt ttgtttttat ggatgccgag cttttttata
      721 agataaggct accgcccata acgacccaag gatttgtgga actaagtaaa tacctgcaag
      781 aagcaagatc agctgggtcg gttttaaagg atgatagaag taacgccatt cagtaaaatt
      841 ggcgcaaaat aaataggaag tgacagtaga tataatattg gcaatgaata aagatataat
      901 acgcctgttc ctttgaaaat aatatccagc aaaaagagat aaaaatatca atgtgatgaa
      961 cccgcttacg gaatgataac gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa
     1021 agataaaagc aacggaaggt ttttccagca agtttttatc atctttcatc accacctaac
     1081 aagtgttatt attttgttag ttttattgta aattgaatcc tgcaataatc aattactttt
     1141 tcattatttc tagattaaat gaataaactc tcatgccatt atctctaaaa aaaaagtttt
     1201 tccccctaat ttttttagat agaaaattgt atagtatgat gagagaaaaa gtagtttggg
     1261 ggaacgttaa tgagaagaaa agcagtaatc gatcggcttt atttattttt ttggtttttt
     1321 cctatcgttt tgctaccttt tacatgggta aatgctgttg tacaaggtgc ggagatatta
     1381 ggcctgatcc aaggaagcgg attagtggtt tctaggaatt ttccagcttt gactgttttc
     1441 tatttagtga taagtgtagg tctcttatta ccaaaatctc tgatcaatca ctacaattgg
     1501 cagctgcttt acttttcttg cttattagta tttacatcta tgttttcttt gctgcctcgc
     1561 ttgattatcg gccctaatgg tttgagcgag agtggattga aggattcagc ttattcctcc
     1621 atgtatttct tgacgatcaa accatggttc tatttagtaa ttgcctcatt tattcttgca
     1681 acattttttt acttctggac agaaatcagg ataaaaagtg aacgatctgt atctataaaa
     1741 aataactatt gatggtggat catcagtaaa aaagcatatg agctgcgtaa aatgcatgtt
     1801 tctcatatgc tttttttatt attatgtaaa gaatgcgaaa aacgtttaca tgatttttac
     1861 ataacttaac tatattttta cagcaaccat acgagggatt tacagtcgac tgataaactt
     1921 tagttgtaaa taagaaagga gcaataaaat gaaaaaagta ttgtttactc taggtatgat
     1981 gggaattctt ttagccggat gcggctcagg atcaggaaat acagatggct ctgccacaca
     2041 aaataattca agtgactcaa atgaacaagt aaaaatcgtt gcggtaggtt cgacagcatt
     2101 acagccgtta gtcgatgcag cacaagaaag ctttgtacaa gaaaatccaa attatcaaat
     2161 ctctgtacaa ggaggaggaa gcggaactgg tttgagccaa gtcgaagctg gagcagttac
     2221 tatcggaaac tctgatgtat ttgcagaaga aagagacgga gttgatgctt caaaattagt
     2281 ggatcataaa gtagcagtgg tcgggatggc accaatcgtc aataaagata cagatgtcaa
     2341 agatatcacc aaacaggaat tgattgatat ctttacagga aaaatcacta actggaagga
     2401 agttggcggg aaagatcaaa aaatcaacgt cgtgaaccgt gcaaacggca gcggtacccg
     2461 cgcgacattc gaaaaatggg gactggatgg tgctacccct gtgcagtccc aagaacaaga
     2521 ttcatcagga acagttcggc agctggtaag tcaaacacca ggagcaatca gctatttagc
     2581 tttctcatat ctcgatgatt ccacacaagc actaagtatc gacggtgtag aaccaaaaga
     2641 agagaatgta gcagataaca gctggggaat ctggtcatat gaacatatgt acacgaacgg
     2701 aaaaccttcc cctgaagtcc aaaaattctt agactacatg atgacagaag aaatccaaga
     2761 aggacctgtc aaagaattgg gctatttacc aatcacaatg atggaagtag aacgtgatca
     2821 cgaaggaaat atcaaataac tagcagataa acatgccacg gtagtcgtta ctattaagga
     2881 aaaatcaact atgtttcccc acatatacat ttttccttta attgtgaaaa atagttcctc
     2941 atattttgcc gttttttgag ctaataccga gggtcagctg attgaacacc gtttattcga
     3001 aaaaaagagc tacgacatag aactgtcgta gctttttttt tgctatatga caggaatgaa
     3061 aggtgtttgc aagcttaatg tgaggaacac tttccatatc tgttctatac tggataggag
     3121 aagtttggaa atatccagaa aacgaaatca atcgaggtag ccacatgaag aataaatgga
     3181 taaatcgaag taaaaaaaag aaagtaacac aaagatcatc agataaagtc atccgtcttt
     3241 ttccatcgta taaagaagga ttaacggcag atcaagtcaa ggaacgaata gaaaaaggtg
     3301 cagcaaataa ttcagtcgat cccacattca aaacaaatca gcaaatcgta ttggaaaaca
     3361 tatttacgta tttcaatttg atctttctta tcttagccat tttgctttgt ttagtagaat
     3421 cctataagaa cttgactttt ttaccagtta tcatagccaa tacaggaatc gccatttttc
     3481 aggaaattcg atccaaaaag atcttggacg aactaaatgt tttaaataca gcaaaagtca
     3541 atgtcatacg agacgggata gaacaaacaa tagatataga agaccttgta atagatgaca
     3601 ttgttatttt agagactgga catcaaattc cagcagatgc agaggtcgtg gaagggaaac
     3661 tgcaagttaa tgaggcttta ttgacaggcg aagcagatga aataaccaaa gaaataggcg
     3721 atccattaat gtccggcagt ttcattgttt ccggaaaagc ttacgcccga ttagacaaag
     3781 ttggagcaga ttcgtatatt tcccagctga cagtcaaagc caagacaatg ggagaaggag
     3841 aacagtcgga gatgattgct tctcttaatc aattgatcaa atggattggg atcatcatta
     3901 ttcctatcgg tatcctgctt ttttctcaaa gttacttttt taatggaaac acgatcaaag
     3961 aaagtgtcgt tgcaatggaa gcagcattga tcggtatgat acctgaagga ctgtacttgc
     4021 tgacgacgat tgcattagca ttaagtgcga ctaaactagc aaagcaaaga gttcttttac
     4081 acaatatgaa aagcattgag acattggcaa gggtaaatgt cctttgtgta gataaaacag
     4141 gaacgatcac agaaaataaa atgtctgttc aaaaagtgat cgtctctaaa aaacaagaaa
     4201 taatcagtca gtcagatcaa ttggaagcat gcattgctga ctatgcaaaa gcgatggcag
     4261 gagacaatgc aacaatggaa gctgttaaag catattttac aaaaaccact gatcaatcct
     4321 atcaccatgt tattcctttt tcttctgtcc aaaaattcag cagtgtagcg ttggcagaca
     4381 aggtgtatgt tttaggagcg cccgaaatgg ttttgcgcga tcaattgccg gaatatgcgg
     4441 aagagtttgt ttctttcgct gaaaaaggct atcgcgtgtt ggtctttggt gtgtacgatg
     4501 ggattcttga agaaccagta ttgacagaag cagtcacacc attaggctat attctgattg
     4561 ctaatcctat cagaaaagaa gcaagagcca catttgatta cttcaaaaaa cagcaagtag
     4621 ccatcaaagt gatttctgga gataatccgc tcaccgtatc caatgtagct gtccaagcag
     4681 ggatttcaca tgctgatcag tacgttgatg catctaaatt atcagaagaa gaatatgaag
     4741 cagctgtcga aaaatataca gtttttggac gcgtcaagcc agaacaaaag aaaatcttcg
     4801 ttcaattgct aaagcgtcgt aacaatacag tagctatgac aggtgatggc gtgaatgata
     4861 ttctagccat gaaagaagca gactgcagta tagcgatggc ttccggaaat gaagccgcca
     4921 tgcaggcctc acaagtggtc ttacttgatt ctgacttttc acgcatgcca gaagttgttg
     4981 cagaaggacg gcgcgttgtg aacaatattg agcgatcagc cagcttgttt ttagtgaaga
     5041 atattttctc ctttttgctc tcactgtttt cagtgatctt tgctctgacc tatcctttag
     5101 aaccatcaca aatcacattg attagtttgt ttactatcgg acttccatct ttcttgcttg
     5161 ctctagaaga aaacaaaaag cgaatcagag ggaaattcat catgaatgtg atggaaaaag
     5221 ctgtgccagg tggactaaca gatatgatcg tagtcggtgc gttggtgatc tgcggggtga
     5281 ctttgaatct aaataaaaca gatgtttcta cagcatctac catgcttttg attgcagtag
     5341 ggttcctcgt tctctataaa atctgttcac cgctgaataa attcagaagt cagatcattc
     5401 ttttctgtgc tagcggtaac tttttttcgg tcatcttttt gcataagctg ttttcaatca
     5461 ccggtatctc agctgtatca cttttgctgt tgagcattct atttttctcg gcagattcga
     5521 tttttaggca tttgaccaca ttggtagaat atttgtttga acgtaaaaat gaaaaagagc
     5581 aaaagccgtt tagtcgcgta gttaaaaaat ttctatcgat atttaaacga gaaaattgac
     5641 gaaaagtatc tcaaaaaaga gtaaaaaaga acaaccactc gtgtatcttt cgaagcagga
     5701 tgagtcatcc aactttaaaa cgcacgagca gttgctcttt tttacatttt cggaatggta
     5761 acggtgaaag tcgaacctgt tccaagatga ctgtctacag taatcgtacc atgaaggagt
     5821 tgcacgtagt cttttacaat cgctaaccct aatccggtcc cgcctgaatg ccggcttcgc
     5881 gccttgtcta cgcggtaaaa acgctcaaag atccgttcct gatcctcaat gtcgatacct
     5941 ataccaaagt cttggacaga aaacgataga tcatctgttg cctgatagcg gataataatc
     6001 tcgctgtcgc tttttgaata ttggacagca ttttcaatca gatttttgat aattggataa
     6061 aggatatctg ttttagtagt aaatggttcg ttctttccaa tcaatcgaat cgtcaaccgt
     6121 ttcttttcga tgattggctg ataattttga acgatttgct ggaaataagg ttctgtataa
     6181 attgtctgga tctcgtaaga attctcgcca tcttttgaca gctggatgat ttcccgaatc
     6241 agtttatcta accggatcgc atctttttgc atgatctcaa gaaaagaagt cagagtttgc
     6301 gggtcatctt ttgcaccatc cagtaaagtc tcggtaaaac caatcagtga agtcacagga
     6361 gtttttaatt cgtgagagac gttgccaacg aaatcctttt gtagcttttc taaacgtcgc
     6421 actttcgtta agtcatacgc cacccctaga atctgtccgg taccttctga attagtaaag
     6481 tagcgcaaac tcaagtctaa tgtctgccga ccttctgtaa gggtgatctc ctgatggatc
     6541 agcggatgct caggagtcac ttgatgaatc agctgaatga gttttggctc ttgaatgact
     6601 tctgtgtacc gctgttcagg ttgatagctt accacgttta aatgtagctg catctttgga
     6661 ttaagcagta gtaaacgaga atcagcatca tcaatcagga atacgccaat catcagttcg
     6721 ttcagtaacg tatataattg ctcttctgtg gtagtatacg cccgatacat cttactcatt
     6781 tgttcgctca acgcattgat cgtctgatac aattcttccc attgatcggg tgtttgcatg
     6841 attacttccg cctgattagg attttgcacc atttttttta gtacgggcag cacggttttc
     6901 aatggctggt ttttttgata gatcagataa tagatcattc ctgcaagaac aaggaagaaa
     6961 gacagaaaga agaaaaagac ccaacggcga aaactctcag ttctcggtaa aaaaccgctt
     7021 gtcggttctg cgatacgtaa aatggcttct aactggccac tttttttgac tggtaatgcg
     7081 acatataaaa gatccccatt caaagtagta cttttgcgca aagcgctacc taggttccca
     7141 ccattcaata cggctttgat ttcgggacgg gagtttcgct gttcattcaa tgtttcattg
     7201 tttgtgtcaa ataagatctt tccagtagca tccattaaag taatccgttc gttcgactga
     7261 tggacgaatt cttccaaagc agttttgttt tgcgctgctt ggaggttttc gacatctaat
     7321 tgccggatca gcagttgtgc tttttttgtc aggtagcttt cttgctgttc cacgatctgc
     7381 tgttgaaaat aatgggaaat caattgccag ccaccaaaaa acaaactaac taaaagaata
     7441 agaaagaaga gacgttcata aatttttttc catttcatcg tttgggttcc tgaaacttat
     7501 agccaaatcc tctaatagtc accaagtact ttgggtgttt tggatctcgc tcgatttttt
     7561 ctcgcaaatg actaacgtgt acatctacga ttcggctttg tcctgcgaag tcaaaattcc
     7621 aaatgcggtc tagcaatgtg tctcggtcga tcacacggtc ttttcgtttc atgaaataaa
     7681 caagtaattc aaattctttc ggtgttagtt caatcagatg gtcgtctacg gtcacttgat
     7741 aattggtcaa atcagcagtg atttgtccaa tcgatagata ttcaggctca gcttcatctt
     7801 ttgattgctt acgaggttca attcgtctga atattgcttt catacgggct aatacttcgc
     7861 gaggactaaa tggtttggtc aaatagtcgt cagcacctat ttctaggcca atgatccgat
     7921 ccacttggtc atctttagcc gtcagcatca aaatcggtgt ttcatttttt tcttgacgca
     7981 gccgctgagt gatctccatg ccatccatcg ttggaagcat cacatctaaa atgatgaaat
     8041 caaatgattg ttctaatgct aattctaatc cttcgcctcc atctgtggca ctggttacct
     8101 tgtagccttc tttttccaaa ttgaacgtca agagcgttac aatagaaggt tcatcatcaa
     8161 caactagtat ttttttcatt caaatctcct ttaaataggt ttcattctgt ttatatttta
     8221 gcatagaatc agtacaaagg gctattttac aaaagaaata aatggtataa taggaaggca
     8281 ctttgctgaa tagaaaggaa gagcagtcaa tgattggaat cagtgcatgt ttaggcggtc
     8341 tggcctgtcg ctatgatgga cagaaaaaag aagtaccaga attgatggaa ctagttgaaa
     8401 ctggagaagc tgtcatggtc tgtccagaag tgatcggcgg attaccaatt cctagagatc
     8461 ccgctgaaat cattggtgga aatggattcg atgtgtggaa agatcaagca aaagtatgga
     8521 cgacaagcgg cgaagatgta acggaagcgt acaaaaatgg cgcgatcaaa gcctatcaaa
     8581 aattgcagga aaaacacatt gatctagtca tcatgaagga aaaaagccct tcatgcggaa
     8641 cccattcgat ttatgacggg agtttttccg gaataaaaaa aaatggtgcc ggagtggcta
     8701 ctgcttattt tattcagcaa aaaatgactg tgctctctga tgaagaatgg ctgaaaacta
     8761 gaggtgagca gaatggaaat cgaaaagacc aatcgaatga acgcgctctt tgaattttat
     8821 tcgaccttat tgacagaaaa acaaatgaac tacatggaat tatattatgc agatgatttt
     8881 tcattaggtg agatcgcgga agaatacgaa gtaagccgac aagcagtata tgacaatatc
     8941 aagcggacaa gcaagatctt ggaggattat gaaaaaaaac ttcatctttt ttctaattat
     9001 attgttcgag aacaggtatt ggaaaatatg actgcatata ttacagataa gtacccggaa
     9061 gataaaaaac tacttgaata tgtacagcaa attcaagcaa tcgaagaata aataaaagga
     9121 atgaagaaaa tatggcattt gaaagcttaa ctgaacgtct ccagcaggcg atgggaaaaa
     9181 taagaaaaaa aggaaaagta tcagaagctg acgtaaaaga aatgatgcgg gaaatccgcc
     9241 ttgccttact agaagccgat gttaacttgc aagtagtcaa agattttact aagcgcgtac
     9301 gcgaacgtgc ggtaggggca gaagtgctgg aaagtttatc acctgcacaa caaatcgtaa
     9361 aaatcgttga tgaagaattg acgatcacac ttggttctga aacagcagag ttaaataaat
     9421 caccaaaaat accaactgtt atcatgatgg ctggtcttca aggggcaggt aaaacgacct
     9481 ttactggtaa attagccaat tatttaaaga aaaatgaaaa tgctcgtccg ctcctaatcg
     9541 caggggacgt atatcgacca gctgcgatcg accaattgaa agtattaggt caacagctag
     9601 acgttcctgt atttgatatg ggaactgaag tcagcccggt agagatcgtc cgtcaaggga
     9661 tggagttagc aaaagaaaag aaaaacgact atgtattgat cgatacggca ggacgtctgc
     9721 atatcgatga aacattgatg gatgagttga aacaaatcaa agaattgacg caaccaaatg
     9781 agattttgct tgttgtcgat gccatgactg gtcaagatgc cgtcaacgta gctgatagct
     9841 tcaaccagca attaggtatt acaggggtcg tcatcactaa acttgatggg gatactcgag
     9901 gcggggcagc actatcgatc cgctcagtga caggcgcacc aatcaaattc atcggttctg
     9961 gtgaaaaatt gactgactta gaagtattcc acccagatcg tatggctagc cgtatccttg
    10021 gtatggggga tatgctgaca ttgattgaaa aagcgcagca agactatgac gagaaaaaag
    10081 cggaagaact tgcacagaaa atgcgggaaa attcattcga tttcaatgac tttattgaac
    10141 agcttgatca agtgatgggt atgggcccac tggaagatct aatcaaaatg atcccaggaa
    10201 tgaatcaagt ccctggaatc gaaaacgtca aggtagatcc aaaagatgtt gaacgcaaaa
    10261 aagcgatggt ttattctatg acgccagcag aaagagcaaa tcctgatctg ttgaacccaa
    10321 gccgtcgtcg ccgaattgct gccggttctg gaaacagtgt tgttgaagtg aatcgaatga
    10381 tcaaacaatt caaggaatca agaaaaatga tgcagcaaat gtccaaaggg gatatgaaca
    10441 tcccaggtat ggaccaaatg tttggttcag gcgtcaaagg aaaactaggc aaaatggcga
    10501 tgaatcgaat gatcaagaaa aataagaaga aaaagaaaaa acggaaataa gatgaaaaaa
    10561 acagcttcgg tacagactga aaatgtctac tgccggagct tttctatcag caatttttat
    10621 tctttactaa tacaattact ctaaacgaag aggtggcaca gatgagatgt ccgtggagtg
    10681 aacaaacaga aagtatgcgg caatatcatg atactgtctg gggtgttcct gaatatgatg
    10741 accaaaagct gttccgaaaa ttgatgcttg atattaatca agccggattg agctggcaga
    10801 cgattttaaa taaaagtgaa gcattcgatg aagcatatga tcgattcgat attaaaaaag
    10861 tcgcaaatta tggagaaaca aaaatcagtg aactaatgga aaacaaagga attattcgta
    10921 accgaagaaa aatcgaagca gccgtccaaa acgccaaagc agtcttgaaa attcaagaag
    10981 aaatcggcag tttttcagag tatctttggt cgttttctaa tggaaaaatc gttgattctt
    11041 cttatcattc acaagaagaa gtcccaacaa caagtcctct ttcagatgaa ttagcaaaag
    11101 atctaaagaa aagaggattt aaatttatcg gaagcacaac aatctatgct tttttagaag
    11161 ctgtcgggat catcaatgat caccttgaca gttgtttccg caaagaagag gtcgtacgta
    11221 tcggcagaaa gggcgaataa agcatgcgaa aaatcatatt ttatggtgct ataagtttag
    11281 atggctattt ggcaacgaaa acggatgatc ttcaatggct ttttgacact ccaacaggta
    11341 agcaaaccac ttatgaagct ttttatgaaa caatcgatac gaccatcatg ggcagaaaaa
    11401 cttatcagga agcaaaaaaa tatttggaga ccgaagcaat ttatccagag aaaaagaatt
    11461 tcgttttttc cacccacgca caattacaat tgccagatgc tgaggtcgta aacgaagatc
    11521 ctgttgcttt tctaaaaaat ctacaaatga cagaaggaaa agatatctgg gttgtgggtg
    11581 gcggtcgatt gatcaaaccg ctattggaac atcaaatgat tgatgaatgg tatatccaga
    11641 ttacccctgt attattaggg gacgggattc ctttattcca aaaaggaaca tatgaagcgc
    11701 gttttgaaat gctagacacg acacgattcg gtgaatttat cgaattgcat tatgtacgaa
    11761 agtagaagta aataaaataa aaaaggcaac tatatgcaga aatgtcctgt acatagttgc
    11821 cttttttatt accgttatgc tttttactct gttaatttgt tagaaaaatc tagatacgca
    11881 tctaaaatcg tttggaagaa acttaatgtt ccttcaacga tattaccatt ttcatcaatt
    11941 agattcgcaa cgtttccgat atatgcttcc ggttgctgca aggttggcac attcaaaaag
    12001 acaagtgatt gtcgtagatg gtggtttgcg ccaaagccgc cgatcccacc tggtgatgca
    12061 gtaacgacta aacctggttt atgatcccaa acactgtgtc cataaggtct tgagcctaca
    12121 tctaaagcat ttttcaatac tgctggcaca gaacggttgt attcaggagt aacgaaaacg
    12181 acaccgtcta gtcccctcac ttcctcacga aaacgagtcc attcagcagg agcctgttct
    12241 ggagtttcga gatcctcatt gtaaaatggc agatcatcga tttttacaaa tacactttcg
    12301 tacccttcag gaagcaattt cgcaaaagct tctgctactt ttttgttgta agaatctttt
    12361 cttaaactac caataaaaaa tccaattttt tttgtcatac gatttttcct ccttcaaact
    12421 atctataaca atcttacaaa aaataagtaa ctggagcaaa taaaaacact tactgacaaa
    12481 agctacatag aagatagatt acttattttt aacaaaaaag aagtctaaaa tcttctattt
    12541 cctaaaaaaa atcgaattta atcaagctgt aaagaaaaaa agctttacag ggtaaaaaaa
    12601 aactgttaca ctacatcttg tgaataaaac aatggaggtg gaaataaata atggcagtta
    12661 aaatccgttt aaaacgtatg ggttctaaaa agagtccgtt ttaccgtatc gtcgtagctg
    12721 attcacgttc tcctcgtgat ggacgtttca tcgaaactgt aggtacttac aatcctttga
    12781 aagaccctgc agaagtagtt ttaaaagaag acttagttct tgactggtta tcaaaaggtg
    12841 cacaaccttc tgacactgta cgtaacatcc tttcaaaaga aggcgttatg caaaaacacc
    12901 acgaagctaa attctcaaag aaataaggtg accggatatg aaagatttaa gcgacttagt
    12961 cttaacaatc gttcgtccgc tagtcactta tcctgatcaa gtcaagttag acgtcgtaga
    13021 gtcgaaagac ttttacgagt acaatctaac agtggctcct gaagatattg gccgtatcat
    13081 tggaaaacaa gggcgtgttg ctaaagcaat ccgcacaatc gtttacggtg ttcggatcaa
    13141 tgcaccgaaa aaagtgcgtt tgaatatcat cgatgataag gaaaagtaaa taaacgtgct
    13201 gtactcgaat tttcgagtgc agcttttttg tttttttatt aattgaagaa atgattattt
    13261 ggcaaaacaa gcaagaaagc gtatccttat aggaggaggg agtgaacagc caatgagaaa
    13321 gaaaatgtta tttattccat ttgctctatt gttaagcgct tgtagttcgg ttactcaaga
    13381 atcagacaat acacatctat caagcagtat atctgaaact gttaccagtc cagaaaaaag
    13441 tagtaccaaa acggctacca ccactgaaca aacaatggct acctcaaata atgagaaaaa
    13501 gactgcttta gaccagttga aagaacaaca gccaaatgtt cccatgcctc tagatgtacc
    13561 agtctcttca ggctatctca atatcgcagc gacacataca aagcaaggtt attctatttt
    13621 atattacaga acagatcgtc ccctcgggtt gaatgctgac gaattgaatc aagaaacgcc
    13681 tattgcaacc tatctatatc aatatgggtt tgcttctagt caagaaacaa tccaagtttt
    13741 gcagcccttt gagatcgaca caaatggtca gcaagtggac ttaggttctc gaatcacagg
    13801 gtatcagcaa ggtgcagcag gttcaagttt tcttgaatgg caagaaggaa actggcgtat
    13861 tcgaatccgt gggaataata tagaaggcca agatccctta ctattagcta aagaaatcgt
    13921 agcttatttg gaagaaaaca gtctaccagc acctgaacaa tttggtaaaa ttactgttga
    13981 tatgggtgat acgacgaatc gagccgtaga agtaagctgg caagaaccga aaaatgccta
    14041 tacgatcact catcaagatc ctatgtctgc gttgaagatg gcagtttcta tgaagaggtt
    14101 gtgaaatcag cgcgctgatc tgagcccatc atttaactcc aagtcacagg aagtaatcaa
    14161 aaatagcacg ccgcattttt gcataatttt ggcttaatac cttaaaagaa aactagaatt
    14221 gcctcttcac acatgctaaa ataaaacaga caaaaaagaa atggggatat aagttgactg
    14281 aatacttgaa tgtaggaaaa atcgtaaaca cacaaggtat caaaggcgaa gtccgtgtta
    14341 tctcaacaac ggatttccca gaagaacgtt acaaaaaagg aacggtgtta acactattcc
    14401 aagacggaaa agcacctgtg gaattaacag tcaaaagtca tcgcaaacat aaaaattttg
    14461 acttattgag ttttgaagga catccttcta tcaatgatgt ggaaaaatat cgggatggca
    14521 tattaaaagt gtcaaaagac aactctgtag atctagctga aaatgaattc tattaccatg
    14581 agatcatcgg tctgcatgta ttagaagatg gaactgagtt aggtaaagta aaagaaatct
    14641 tgtcaccagg tgccaatgat gtttgggtcg ttcaacgtcc gaaaaaagct gatatattgc
    14701 ttccatatat cgcttctgtc gtcaaagaag tcgatttaga agctggagtg gtccgtgtag
    14761 aaattccaga aggactgatt gacgatgaag attgatgtat tgactttatt tccaagaatg
    14821 tttgaaggtc ctatggggga atccatcatc ggtaaggctg tagataaagg attattagat
    14881 atcaatatct ctaacttccg cgattattca gataacaaac atcagacagt agatgattat
    14941 ccatacggcg gtggagcagg tatgctgctc aaagtccagc ccatctatga taacatccaa
    15001 gccattgaaa aagctgcacc ggatgtcaaa aaaagagtaa ttcttcttga cccagctggt
    15061 aaacgattcg atcagaaaat ggcagaagaa ttttcacaag aagaacactt agtattcatt
    15121 tgtggtcatt atgagggata tgatgaacgt atccgcacat tagtgacaga tgaagtttcc
    15181 ttaggagatt atgtccttac tgggggagaa ttaggtgcga tggtcatgat cgatgcaaca
    15241 gttcggcttt tgccagatgt gttagggaat cagacttcag ctcaaacgga ttcttattca
    15301 accggtttat tggaacatcc ccaatatact cgcccggcag aatataaagg gatgaaagta
    15361 ccagaagtat tgacaaatgg aaatcataaa ttgattgaag aatggcaatt aaaagaatca
    15421 ctaagaagga cctatcaacg tcggcctgat cttttggaaa cacttgaatg gacacctcaa
    15481 atgacgaaat ttttagaaga aatcaagaaa gaagaacaag aaaaaacagc agatgaagcc
    15541 aagtgacttt ttctaaaata ttctttacag taggttgata atatgttagt attttatggt
    15601 gagtgcaaaa gcacttaact attacgatat tccgctatga gaaaagctca taagaatatt
    15661 tggaataagg agaagaaaac catgaatcca ttaatcgaag aattaacaaa agaacaatta
    15721 cgttctgaca tcccagcgtt ccgccctggt gacactgtgc gtgttcacgc aaaagttgtt
    15781 gaaggtactc gtgaacgtat ccagttattt gaaggtgttg ttatcaaacg ccgcggtgct
    15841 ggaatcagcg aaacttatac agtacgtaaa gtttctaacg gagtgggcgt tgaacgtaca
    15901 ttcccattgc atacaccacg tgttgcaaaa atcgaagtag ttcgctacgg taaagtacgt
    15961 cgtgcaaaat tgtactacct acgtgcatta cacggaaaag ctgctcgtat caaagaaatc
    16021 agaagataaa cacggaaaac ttccttggaa atctgaaatc tgtgaaaagt ccttgtatat
    16081 caaggacttt ttcttttttc tctatcacat tttgaaagtg ttttgagcct ttttttctaa
    16141 tattctctca aattgtcctg aatctcccaa tattgactac tattatcgtc aaaatatcga
    16201 aaaatttagt agtcattttg acgacaaatt taatacgaaa aataccaaaa cacttaccga
    16261 atttagcaat ttttgaaccc gagttgctta aaaggttgaa tgttttcgaa aatagcaaaa
    16321 catataccat tgtgctaaaa agttaatgtg ataggtttct atttaaataa ttctaggagt
    16381 ttttttgtaa tgggaaaaga taagcgtatt gtttggaagg atcaaagcga tttaaaaatt
    16441 attttaacaa ttagtcagtt tattgaaaca tacgaaataa aatctagtcg agaatatcag
    16501 aaacagttat cgaaaaatcc aaactcagct cccagcatgt ggtttattat taataaatat
    16561 ggctcgtgga ataatttgct gaacagcatt ggaattgaca atagcggatc taaaaaatgg
    16621 gctaaaatgg agaccgatga attaataaaa gtggcacaaa tatttattga ttcagaaaaa
    16681 ataaaatcac aacgcgttta tgaaaaaaag tctgttggta aagatgttcc gtgtataagc
    16741 actttaaaga atagattggg cgacattcgt tttctattta aaaaggaagt gaataaggga
    16801 ctaactaatt ttgagatact tttagagctt aagaatgaaa taattagact taatatggaa
    16861 gatgatttat ctatgacaaa atttcaaaac tattcaaaat caaaacatct tccatctgtg
    16921 tatacaatta tgagacggac caataagaca tgggaagaat tgatgagcga aattggatat
    16981 gattatagaa aaatcaaaat aaaaaaacag agaaataatt tgcggtgtag atcaaaaaat
    17041 aatatgtcca agacatgaat aaacaaagta tttttcaaca gtgtttttat ctgtaccatt
    17101 ctttaaatat tcatagcagt ttattcatgt tttatgaggt ttaaaataca atactgaatt
    17161 tactgcttat ttttacacta ctgcataaac tttgtattct aatagaaaat agagttgtga
    17221 atgaaaaata cttatttcta ttacaaaagg taaaaaaata tcgatttaaa agctaaatgg
    17281 acacatgagt ttgggatttt tctacttcaa tttcaaaatg agagtagcag ataaggggat
    17341 gataggaatg taccaaatac taatctagat acaatatgca tatataggct acacttcttt
    17401 agattttttg attaagaaca taataaatag tttacgtcga tacttattaa gttatcgacg
    17461 ttttttatta taaaaaaata ataaaggagg tttcttgata tgataagaaa caaaaagtgt
    17521 tggttgaaag ttgctttact ggcagttttt ttctaagtaa ctttttgaca agctcaatgg
    17581 caacacaagc ggaagaagta atacaagaaa taactgttat gaataacagc tagataaaat
    17641 gggctaggta tgttatccaa caatttagta atcactagaa gcctagcgaa agttcgcttg
    17701 ataagttata gatgagtatt gatttgtagt gtttccaaat caaaagggta cagagccaca
    17761 tgaaatatgt tgtcctctgc agcgtcagga tgggaatcca taccatggag attcggagat
    17821 ctgtgaggga atacttacgt ggttaatatg tcggttgtgt tggaagtagt aatggtcata
    17881 gtgggtaaat tgactgaatt cttatatgag aaaatgaaac caacaagaag atagggttat
    17941 ttatacagaa ttggggatct tttctggaaa agtaatcgga caatgcgaga ttcgtacggt
    18001 cttttttaaa tttct
//
LOCUS       DAYYEF010000055        17006 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000055 DAYYEF010000000
VERSION     DAYYEF010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.057"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..125)
                     /locus_tag="ACHA1B_002169"
     CDS             complement(<1..125)
                     /locus_tag="ACHA1B_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HFM8702918.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFS"
     gene            complement(229..540)
                     /locus_tag="ACHA1B_002170"
     CDS             complement(229..540)
                     /locus_tag="ACHA1B_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFM8702919.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(542..739)
                     /locus_tag="ACHA1B_002171"
     CDS             complement(542..739)
                     /locus_tag="ACHA1B_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFM8702920.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1133..2860)
                     /locus_tag="ACHA1B_002172"
     CDS             complement(1133..2860)
                     /locus_tag="ACHA1B_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HFM8702921.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2853..4046)
                     /locus_tag="ACHA1B_002173"
     CDS             complement(2853..4046)
                     /locus_tag="ACHA1B_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HFM8702922.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4233..4877)
                     /locus_tag="ACHA1B_002174"
     CDS             complement(4233..4877)
                     /locus_tag="ACHA1B_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM8702923.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4971..5105)
                     /locus_tag="ACHA1B_002175"
     CDS             complement(4971..5105)
                     /locus_tag="ACHA1B_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HFM8702924.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="ACHA1B_002176"
     CDS             complement(5107..7239)
                     /gene="feoB"
                     /locus_tag="ACHA1B_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0005525 - GTP binding [Evidence IEA];
                     GO_function: GO:0015093 - ferrous iron transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HFM8702925.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7236..7709)
                     /locus_tag="ACHA1B_002177"
     CDS             complement(7236..7709)
                     /locus_tag="ACHA1B_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HFM8702926.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8110..8334
                     /gene="nrdH"
                     /locus_tag="ACHA1B_002178"
     CDS             8110..8334
                     /gene="nrdH"
                     /locus_tag="ACHA1B_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HFM8702927.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8493..10652
                     /gene="nrdE"
                     /locus_tag="ACHA1B_002179"
     CDS             8493..10652
                     /gene="nrdE"
                     /locus_tag="ACHA1B_002179"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HFM8702928.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10702..11667
                     /gene="nrdF"
                     /locus_tag="ACHA1B_002180"
     CDS             10702..11667
                     /gene="nrdF"
                     /locus_tag="ACHA1B_002180"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA];
                     GO_function: GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA];
                     GO_process: GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HFM8702929.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11756..12895)
                     /locus_tag="ACHA1B_002181"
     CDS             complement(11756..12895)
                     /locus_tag="ACHA1B_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HFM8702930.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13204..13917)
                     /locus_tag="ACHA1B_002182"
     CDS             complement(13204..13917)
                     /locus_tag="ACHA1B_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HFM8702931.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="ACHA1B_002183"
     CDS             complement(14171..14872)
                     /gene="nagB"
                     /locus_tag="ACHA1B_002183"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004342 - glucosamine-6-phosphate
                     deaminase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HFM8702932.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15106..16638
                     /locus_tag="ACHA1B_002184"
     CDS             15106..16638
                     /locus_tag="ACHA1B_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HFM8702933.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16829..>17006)
                     /locus_tag="ACHA1B_002185"
     CDS             complement(16829..>17006)
                     /locus_tag="ACHA1B_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM8702934.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5278 a         3495 c         2910 g         5323 t
ORIGIN      
        1 gaaaaaacac attccactaa atttgatgcc ggttttcctt gaggttttgt tccagcacct
       61 cctttaattt ttttaagctc ttgatctgaa cattgtttag catttagtct atttttttct
      121 tccattacga ttccccctac aaactataaa tacttttatg tcactgattc aatataccta
      181 tttttctaat caaaaaattt tgagacatat ttaatattat aagtatcatt aaaattgaga
      241 tttatctcca taatctgctc gatataaacc atttattcca gcagttcttc caatttcact
      301 caaatttctt attaattcct cttgatattc agtgaatctt attttattag tataagcagt
      361 aaaatataga taattcacca atctatttat taaaggactg ggatctaatt catatttttg
      421 tttttctaat tttaaatata ccttttgtaa aacctcaaga atatcagaat atttaggatc
      481 tttacttata gatatatcat tatataattc atgaacaatt tgcttagcat tttttttcat
      541 tttagcactt ccctggaatt gctccaccta aaaaaccacc tatagacatt cctgcaatac
      601 aagtagttgc cttggcccaa tcgaccgtac atttattttt agtgcaatac actccatttc
      661 cataatattt tccactatga gtggtacccc catagataag ttgtgtctct ttaatagaca
      721 aaatttttaa atgtttcata atctaatcac ccctaaatta atgtttttag actattattc
      781 taacattcat taaatttcaa aaaacaattc cttcttgaaa cgtagcaaaa taattcctga
      841 ataagaattt aatcactttt aagtatataa actatgtata ttctttaata ttttttgaga
      901 atgcacttcg tacataataa actttaatca cattagtctt tcatacctac gatcgatctc
      961 tttgactcgc acccataaat tcataatagt ttgtcggcgt ctttgaacgt ttcgaagatg
     1021 agctacgcat tctctttttt tatagacaaa aaagatagag acgaacatgg agcttccaaa
     1081 tttggatatt tgatccaatt ttggaagctc catttatttc gtgtctgtct ttttattttt
     1141 tccagctttc gactaattct tggttctctt tgatccagtc ttttgctgct tgctgtggat
     1201 cttttccatt gttgatttcc aacataactt tttccatatc tttttctgac caatggaaat
     1261 tgtctaatac tttgtaagct tctggctggt cttctttcaa tccttttcga accatcgtat
     1321 ggatctgctc ttcgcttccc attccgtttt caggatcttc taagtatttc agatcatatt
     1381 tggcaaacat ccaatgaggt gtccatcctg taactacaat tggttcgtgt tttttgatcg
     1441 cttgacctag tgcaacggtc attgctcctg aagaagatgt ctctactttc cagtctttca
     1501 agttgtcata tttttggatc gtgttttcag cagccgtaac tacaccagct cctggctcga
     1561 ttcctatgat tttcttacct gcctgatcgg ttaactcatc gatcgaattt acatccatgt
     1621 aggctggcac tgctaaacca acttttgctc ctgtcaaatt ggcacctagg tcttcgactt
     1681 gatctttata ttgtgcatat tgtgaaccat gagttttagg tagccaagct gaaaccatgg
     1741 catctgactc gccatttgaa acagatttcc acatgattga attatctaat ggcgtcatcg
     1801 ttacatcata gcccatttgt ttcaatactt caccgactac atttgttgaa gcaacttctg
     1861 tatcccattc aacataagat aagttgatac gttttgtttc tttggcagat gaaaaactcc
     1921 ctataccaat cgcacctaag atcactacta ctacagcacc aatgatcagt ccttgacgtt
     1981 ttttactttt ctgtgttgtt gctcctgcag cttttttatt gtttggctgg ttcaaatgct
     2041 gtgtaaaacg gtcaatgatg attgctaaga taactaatgc aaccccgttg acaaatccat
     2101 tcccgacttg tgctctttgc aatgctgata atacgccgcg tcctaagccg ggtgcaccga
     2161 tcatagaggc aataacgacc attgaaagtg acagcattgt tgtttgattg atccctgcca
     2221 tgatcgtact tttagctaaa ggcaattcta gtttgaatag tttttgacga cttgtgctcc
     2281 cgaatgaatc agaagcttct actaattctt taggaacttg tcgaatccct aaattcgtaa
     2341 aacgaacggt tggtggcaga gcaaagatga ctgaggcaaa tacccctgga accatcccga
     2401 taccgaaaaa tgcaactgct ggaatcaaat aaacgaatcc tggcattgtc tgcataaagt
     2461 caaggatcgg tttgataata ctttgggctt tactgctttt tgccatcaag atccctaatg
     2521 gtaccccaat gatgatcgag atcacactag ataaaagaac aagtgtgaca gtattcatca
     2581 aatcattcca tagaccttgg ttataaataa accatagacc gattaatgtg aacaacgtaa
     2641 gtcctggacg tttcttagaa ataaagaaag ctgctaccgt caataacaag ataaacaaag
     2701 gagctggaat cactaacagt aaatttgtaa tccccgacat cactgcctgt ccaatcgttt
     2761 gtaaaaatga aaataggcca gaaaaagttg tcgtaaacca ttctgtgata ttttctaccc
     2821 agtttgccac tggtaattga tagttcaata gattattcat gttcactcac ctcgcttgtt
     2881 tctgctaatg cttcaatcac actacctcgg atgacgacac cttttaattt tccatcctct
     2941 acaactgcaa gtggagtcgg tgagtcataa ataatattga aaatatcact taccaccatg
     3001 tctttcccaa tcaccgtcac attttcatct aggaagtcga tcaatggacg tttttgcttc
     3061 ctagcttcta acgcttgatc tgcagtgatg atccctttca ggtgtctctt tctgtcaaca
     3121 gccatcagca tgctgacttc ttcattacgc atccttgtca atgcaacgtt tggtccatca
     3181 gattcgatat tcgtcgtcaa tgcaggtacc atgatgtttt gagccgtaag cactttggaa
     3241 cgatcgactt cttccacaaa ttcacgtaca taatcatttg ctggattggt caatatttct
     3301 tcacctgttc cgatctgcat gatttcgccg tctttcatca aggcgattct gtccccaatc
     3361 cgtaaagctt cattcaaatc atgggtaatg aaaataatcg ttttttgaac attggcttgc
     3421 aggtccagta attcgtcttg catttctcgc cggatcagcg gatcaagagc cgagaacgct
     3481 tcgtccatca gcaagatctc aggatcattt gctaaagctc tggctaggcc aacccgttgt
     3541 tgcatcccac cagataactg actaggatat tggtctttaa atgaaagcaa actagaattt
     3601 tctaatgctt tttctgcttt ttcttgtcgt tcttctttag gtacaccacg gacttctaac
     3661 ccgtattctg tattttccaa gatcgttcga tgtggaaaca gaccgaagtt ttggaaaacc
     3721 atattgattt tatgacgacg gacttctcgc aattcttctt tgcttaactt cgatacatct
     3781 tctccatcaa tatagatact gcccgaagtt ggctcaatca gacgattcaa tagacggatc
     3841 aatgtggatt tcccactccc ggaaagcccc atgatcacga agatttctcc ttcttttacg
     3901 tcaaaattca cgtcatacac accaaccgtt gcaccggttt tctttaaaat ctccgttttc
     3961 ggctggtgat cattcatcat atctaaagcg gcttgtgtct ttttaccaaa tatctttgtt
     4021 aaatgtttta cttctacttt taccaaacaa attctccttt tttatgtaaa ttcatttttc
     4081 tttctgaaaa aagtgaccac actatgttaa catcatgtag tcactttgtc aaaaatgaaa
     4141 gaaatttgct tgtccaaact gaaaaaaact tggctaaatc tttgtaaata aaaggtttag
     4201 ccaagttaat atttttttaa tatttcacac aatcattctg caagctgatg ctccgggtaa
     4261 aaaaagtttg tcatacgctg tagtgtatat tcatttccaa taaaatgaac gatgtcccct
     4321 gccgtaaatt tagcataggg gccaggtgaa acaagcagtt cttcattatg agaaattgcg
     4381 ataactgtgg cgccagtcgc ctgccagata ttcaactcgc taattgaacg gtccagatgc
     4441 attgcttttt ctgataaaga taattcaaac ggaagtaaag gattcatctt atgtattcgc
     4501 ttcgtttgat tgaccagctg atccaataat tgagaaaaat gattcagctc atcttgttgc
     4561 ttctccacac ttgccatgat ttctgctttt gtatcttgga tggattgtac atcttgatat
     4621 tgcaatagga aatcttttgc tttttccttc gaagcaacaa atgccccact tccatgccgt
     4681 acttccatga ttccaagatc taccagcaca ttgatagcct tgcgggtagt ctcaggagaa
     4741 gcattgtacg tactggcaag tgttgagcgg gcatggatct tctcacccac tttatatcgg
     4801 ttttcaacga tacgttcggc taaatcaaca gcaatctgct ggtagcgcgg gcggacgatt
     4861 tttttctttc cagacatttt ctttcctctt tcttttttta ctttccctca tcttactatg
     4921 ctctagcaaa ataagcaaaa aaggggagaa tagcctcttg caacgactga tcatcgcttg
     4981 atctgttcct tttttactgg gcaagctgtt tgacagtcat cacaattctt accggatttt
     5041 aaacgagtat agacaattgc gcctgcactt ccaaagatta acacacttaa taagaatgtc
     5101 gccatcctat tcctctcctt ctaatgacaa tatagtataa aactggttct tggattttgg
     5161 ctgacggaac aaaacataaa cgagtcctat catcagtaaa atagcaagat acgtccctaa
     5221 cgctacctgt ccaccctcca ataagtgtcc caactgataa atcacaaaac taactaaata
     5281 agctaaaccg cattgatagc ctatggcgat ccaagtccat ttcttggcat tcatttcccg
     5341 atggatagcc ccaattgccg caaaacaagg cgcacaaagt aaattgaagg ctaacaatga
     5401 ataagctgct gcgggagtat atgtgtgttg tagcacttgc cagatttctc tgccattttc
     5461 ggatacttcc gcatgaccaa acaaaatacc aaatgtgcca ataatatttt ctttagcgac
     5521 caatcctgta atcgctgcga ctgttccttg ccagtttccc caaccaagcg gctgaaaaac
     5581 aactgccagg attcgcccga aaaaggctaa gatactttgg tcttcagaaa caggttgagc
     5641 ataaaaatta taagaagagc tgaaccagat cacgatacta gaaacaaaga taatcgttcc
     5701 tgctttttta acaaaagact tgctgcggtc ataggtttgt cttaggaccg ctgaccattg
     5761 aggaaaatga tatgcgggca attccatgat aaaaggagct gtatctccag caaacaaacg
     5821 tgtttttttc aagctgattc cagagaaaat aattgcagtc ataccaagaa aataggcaga
     5881 aggagctacc caagattgat gaggaaaaaa ggcccctgct actaaggcaa taatcggcaa
     5941 ctttgcagaa caaggcatga aggttgtgac catgatcgtc aaacgacgat cttgctcgtt
     6001 ttcaatcgtg cgactggcca tgacgcctgg cactccacat cctgtagcaa tcagcatagg
     6061 aatgaaggat tttcctgaaa gaccgaattt cctgaaaagt cgatccatga caaaagcgat
     6121 cctcgccata tatccgcagt cttccagaaa gctcaagcat aaaaacaata taatcaattg
     6181 cggtagaaat cctaacactg ctcccacgcc tgcgatgatg ccgttcaaga tcagctcctg
     6241 catccatccc gctacttgcc attcagctaa caatctgcca acatgttctg gtaaccatgt
     6301 accaaacaat gtgtcattga tccaatctgt ccccattgtt cctactgttt gaatagccag
     6361 ataatagatc agccacatca caaatgcgaa gatcggcaag gctaaccaac gattcgttgc
     6421 aatctgatcg attttgtcac tcatcgataa ttggaaagaa tcatttgaca caacacagag
     6481 tgtacatagt tgggtaataa attcataacg ttcattgacc agaatcgtct cactatcgtc
     6541 gtccaatagt ttctctgtta actggatcag ttgctcgatc tctttttgct gagaaactgc
     6601 tatctcgtaa tcctctctta ccttctgatc tcgttcaaaa tatttcattg cataccagcg
     6661 tttcttgccg ctttgttctc ctagtacatc ttcaatttca tgtaaagctg cttctaaacg
     6721 tggatcatat gtacagggaa caggaataga aggccgcttt tttgcagact cctgaatctt
     6781 ttcgattagt ttttcgattc cttgcttttt caatacgctg attggtaaaa ctggtacacc
     6841 aagaccatag gaaagctttt ctagattgat tttttttcct tcttttttga tgacatccat
     6901 catattcaga ccaatgatca taggaatgtc taaatccaat aactgcgtag ttaaataaag
     6961 atttcgttct aaattggtag catcaataat gttgatgatc agttcaggct gttcctgaac
     7021 caaataatct cttgcaatca cttcttctgg tgtataagga gacaaagaat agatgccggg
     7081 taggtcctga atatgaatgt tcggattttt tttcaacgat ccttcttttt tttctactgt
     7141 tacgcccggc caattcccta catattgatt cgaaccagtc aagagattga acaagctagt
     7201 tttcccgctg tttggatttc cgactaacgc gatattcatt ctttttcctc cctttgtatc
     7261 aagattagtt cggcctctga ctttcgtaac gtcagttcat accctcgcac tgtcagttcg
     7321 attggatctc ccagaggggc tagttttcgg ataactattt ttacatttcg cgtcaatccc
     7381 atatccatta accgtcgctt cactgcgcct tgtccgtgga ttgctacgac gatcccagtc
     7441 tctcctgctt ttaattgatc aagagaagtc cagctttcag aggaagcagt ctttttattg
     7501 acaaagattt gacctagtat ttcccgactt actgccactc gatgactttt taccagtaaa
     7561 atggcattgt tgcctgataa attgacgacg acgattttac ttccggcaac gatcccgata
     7621 ttttgcaaat ggcgttttgt tttttcttct gtttcgattc gttcgacttg ataaacgaaa
     7681 ttctgctttg cctgcgctaa ggtctgcata ttgattcctc tcttgtgaaa taaatcatgt
     7741 attaaaatca ttcattatat gttctaattt tcttacgtgt tacgcaaata aatgagaatc
     7801 attctcacat agaatactct cggtaattga gaatgtcaat tatacttgtg atattatgag
     7861 cgaatcttta gtattgatag ataaaaatga gaaaaaaata tttcttcata gttttccaca
     7921 attttttctc tattaaattt gctattttcc cacacgatac ttgttttcag ctcttttttc
     7981 aaaaacacaa aacttagtat tccacagttt ccacaacaca atatgtagtg tttgttgttt
     8041 gactttttta ctaagagttt tatactatct attatagata ataagaatgt gttagaggag
     8101 gcactcacca tgaacgtaaa aatcttttct aaaaataatt gtatgcaatg taagatggtc
     8161 aaacggtttt taacagaaaa tcaaattgct tttgaagaag tcaatatcga tgaacagcct
     8221 gaagcagtag actggttgaa agcacaagga ttccaaagtg ttcctgtcat tacttctgat
     8281 gcagaaacag ttatcggatt ccgtcctgat cagttgcgta aacttgccag ctaacatgac
     8341 taaaagaatc aaaacgtgat acatggattt gaagggcttg agacagcacc agtttttgtc
     8401 gcaaacttcc aaatcctttt ttaaagctta aaaacaatgc aatgatttgc aatcaagcat
     8461 catcaaatac gaaatgaagg ttgggcgtac gtatgagtct taaaaattta caagatgtca
     8521 gttatttcaa gctgaataat gaaatcaatc ggccagtcaa tggtcaaatc cctttgaata
     8581 aggataaaga agctttagtt gccttttttg aggaaaatgt caaaccaaat acgatgactt
     8641 ttccatctat tatggaaaaa atcaattact tgatcgatca agaatatata gaagcagaat
     8701 tcattcaatt gtattcacca tcatttattg aaaagctata tcaatttttg gacgagcaac
     8761 atttttcttt caaatctttt atggctgctt acaaatttta ttctcaatat gcgttgaaaa
     8821 ccaacgacgg ttccgcttat ctggaaactt atgaagatcg agtagccttc aatgcgcttt
     8881 actttgcgaa cggggatgaa gaattagcac ttgctcttgc agacgaaatg atccatcaac
     8941 gatatcagcc agctacacct tctttcttga atgctggacg taaacgtcgg ggcgaattgg
     9001 tgtcttgttt cttgactcaa gtcactgacg atatgaactc tatcgggcgc tcaatcaact
     9061 ctgctttgca attgtcccgt attggtggcg gcgtagggat tactttatca aatcttcgtg
     9121 aagccggcgc tcctatcaaa ggatatgagg gtgctgcaag tggtgtcgtt ccagtcatga
     9181 aattattcga agatagtttc agctattcta atcaattagg tcagcgtcaa ggagctggcg
     9241 tggtttattt gaacgttttc catccagaca ttattgcttt cctttcagca aaaaaagaaa
     9301 atgcagatga aaagattcgc gtaaaaactc tttctcttgg cgtgatcgta cctgataaat
     9361 tttatgaatt gacacgtaaa aacgaagata tgtatttatt tagtccatat agtgtcgaaa
     9421 aagaatatgg tgtcccattc tcttatgtaa atattacagc tgagtatgat catctagttg
     9481 caaatccaaa cattcgcaaa caaaaaatca aagcgcgtga tcttgaaaat gaaatctcaa
     9541 aattacaaca agaatctggc tatccttacg taatcaatat tgatacagcg aaccgcgaga
     9601 atccaatcga tggcaagatc atcatgagta atttatgttc agagatttta caagttcaaa
     9661 cgccttctgt gattaacggc aaacaggaat atgaagtatt aggaacagat atctcatgta
     9721 acttaggctc gacaaatatc gtgaatttga tgcaaagccc taactttggt caatctgtgc
     9781 gtacgatgac tcgtgcattg acatttatta cagatgcatc tgatatcgat gtcgtaccac
     9841 cgatccaaaa cggaaataag ctgaatcata cgattggatt aggtgccatg ggcttacaca
     9901 cttatcttgc aaaagaacaa atggaatatg gctcagagga ttcattagac tttacaaata
     9961 tttacttcat gctgttgaat tattggacac ttgttgaaag caacaatatc gctcgtgaaa
    10021 gaaaacaagt tttccataat tttgaaaaat cagcttatgc tgacggcact tatttcgaaa
    10081 aatacgtaac tggagaattc cagccaaaat cagaaaaagt caaagcattg tttgaaggca
    10141 tttttatccc aactgctgaa gattggaatg ctttgaaaca agcagtaatg aaagatggac
    10201 tgtatcatca aaatcgcttg gcagtagcac caaatggctc aatttcatat atcaacgata
    10261 cgagtgcaag tattcatcct atcactcgca tgatcgaaga acgccaagag aagaaaatcg
    10321 gtaaaattta ttacccagcg ccttatctat ccaatgagac gattccgtat tacacttctg
    10381 cttatgatat ggacatgcgt aaagtaatcg atgtttatgc aacggcacaa caacacgtcg
    10441 atcaaggcat gagtttgact ttattcatgc gttctgaaat cccagaaggc atttatgaat
    10501 ggaagacaac aacgaagcaa acgacacgtg atttgaatat tttaagacat tacgctttcc
    10561 acaaaggaat caaatccatt tattacgtac gtacctttac tgatgatgca gaagaaatcg
    10621 gaagcaatca atgtgaaagc tgcgtgatct aatatcatag atagattcgc ttattcatat
    10681 tttaattaaa ggagcattct catgtcagaa acatattatg aagcaataaa ctggaatgaa
    10741 attgaagata tcattgataa atccacttgg gagaagctga cagagcaatt ttggctagat
    10801 acacgtatcc cactttcaaa tgacctagat gattggcgta cattgtctca attggaaaaa
    10861 gatacagtag gacatgtatt tggcggtttg acactgctag atactgtcca atctgaaagt
    10921 ggcatggatc agttgcgtaa agatgtccgc actccccatg aagaagccgt tttgaacaat
    10981 attcaattca tggaatccgt tcatgccaaa agttattctt ctatttttag tacactgaat
    11041 acgaaaaaag aaatcgaaga aatttttgac tggacaaata cgaatcctta tctgcaaaaa
    11101 aaagctgagc gtatcaatga aatctacaaa cacggtacac cgctagaaaa gaaaattgcc
    11161 agcgtctttt tagaaacatt cttgttctat tcaggttttt atactcctct ttattattta
    11221 ggaaacaaca aattggctaa cgtagcagag atcatcaaac taatcatccg agatgaatct
    11281 gtacatggaa cctacatcgg ttacaaattc caattaggat tcaacgagtt acctgaagca
    11341 gaacaagaaa cgttaaaaga ctggatgtac aatcttcttt atgagcttta cgaaaacgaa
    11401 gaacgttata cagaagaatt atacgatcca atcggctgga cagaagaagt caagacattc
    11461 ctacgctata atgccaacaa agcattgatg aacctaggga tggatccact ctttccagat
    11521 actgccaatg atgtcaaccc aatcgtaatg aacgggattt caacaggcac aagcaaccat
    11581 gacttcttct cacaagtcgg aaacggctat ttgttaggtc atgtagaagc gatgaaagac
    11641 gacgattatt tgattggatt ggaataagga tttattttaa ttcaaaaatt tttcgaaaaa
    11701 taaaaagagt ttagcgtaca gatattttaa atgtacactg aactcttttt tatgcttatt
    11761 cacttgtttc ttccagcact tttggactgt ctaacttttc cgaaacatgt tccattcttc
    11821 tcaataaata gattttccgg atatttaata ttatcgtctt aatcactgca tagacaggta
    11881 tgcaaatcag catgcctaat attcctgcga cacttcctgc tccaatcaat accaagatga
    11941 tcgtcaaagg atggatattc attgatttcc caaataacaa cggcttgatc aaatttccat
    12001 ctaattgttg gatcactaaa atcgacaacg ccatatacaa agcttgaaat ggagagataa
    12061 acaaaccgac aatgattgct ggtaccgctc caataaaagg gccgacatac gggataatat
    12121 tcgtgattcc gcaaatgacc gcaagcaaca agctataagg ctgatcgaat attctcattg
    12181 ccaaaaagct cattacacca ataatcaaag catctaagat cgtactgctg atataggcag
    12241 ataatgtttc gtttaattct tttaccgttt ggcgtaactc tttacgaatc gctttcggaa
    12301 agaagtgaga caacgcatca ataaatttgt gcccatcctt gaacataaat agcaaaataa
    12361 atggaacggt aaataacaaa ataaaaaatt gcatcataaa tgaaatgatt tttgagacac
    12421 ttgcagataa actgactaat atgatattga acaaattact aagagataaa tttgctgatg
    12481 ctaattgttc ttccaaattg aaatttttaa actcttcccg ctgcgccaat tcatttaacc
    12541 atttgcttgt ttcatctgca tacattggca agctctgggt caattgaatt gtctgttcca
    12601 ttaactgagg cactacattc atgacagtta aaacaactaa aatgattacg accaaaaacg
    12661 tcaataaaaa accgaacact ctcgggatcc gatgcttttc gagaaaaaca acgattggat
    12721 cgaacatata atagataaaa ccagcaacaa gcaatggtaa aaaaattgcc gaaagcattt
    12781 tcaatattgg actaaaaata ttcggcattt gtaaaataaa gtacacgccg atgatcgtga
    12841 gtactagctc cactgtccag aaaaataatt ttgattgttt aaaacgtgat tgcatacatc
    12901 tcctccaagg tcctttgata cttctattct atcatttaac aaagagttac gcgctgagat
    12961 tttcatttgc ttaaaaaaaa caaaaaaaat aaacatattt taatgagtag acgagtactt
    13021 aaacaaaaac acggtttgga gtagtgacaa aaattatact gcagtccctt tttccaaata
    13081 aacggtgttc aaaagcttgc atcttcgtaa taagcccagc caaacgaaaa atataaggaa
    13141 ctatttttat ttggctgggc ttattacttg atgtaggaca tctattttac aacctcagat
    13201 catttattgc gcaatactga ctaaatgcaa ctttgtgata tttttgtgta cggacaactc
    13261 ctcgatcaca tcggcataag tgagcccttt tggaagatca atcgtataga tatttttgta
    13321 cactcggtag tcatcaacga attttacgtc aaaattcaca tcttcgatta cgatattttt
    13381 ctcttcaaaa taatcggtaa gaaaatcttt ggtttctttt ctatggataa attggatttc
    13441 taacttttta gtcgtaggta catggatcac gcgtttcact actgtgagtg caatagcaat
    13501 cccgataaaa ctgatgatcg caatggaata gtaacccatg ccgatggcga tccctaatcc
    13561 agcaattgcc cataaagaag cggcagtcgt aagtcccgtc accgattgtt tcgtgacgat
    13621 gatcgttccc gcgcctaaga aaccgacacc actcaccact tgagcaatca gccttgcttc
    13681 atctgaacga atcgttccag caagctgtgg atactctaaa gcatctctta atgcaccact
    13741 agcgatctca acttggatca atgcaatgat acatgctccc atacaaacta aaatatgcgt
    13801 acgcatacct gctggacgat ttttatattg tcgttcaaaa ccgattgctc cgccaaatag
    13861 catagcgatc cctaaacgta aaataatctc tggaattgtc aataccatat cattcatcta
    13921 aacaccctcc agtccaatat atcatgtctg aaaggagcag acaaaaaaag tgcaattttt
    13981 acctcttacg aaaaaaggac tgtgacaaaa tttttgtcat agtccttttt atgaataaac
    14041 ggtgttcaat cagctgaccc tcggtattac tcaacaaacg gcaaaatatg gggagctatt
    14101 tttcctttgt cttctctaat actcaggtca aaacgctgat ttcacaacct ctttagccta
    14161 ctattgaaaa ttacaactta cttgctgctt cttcatcgat gatcacaaca acattgtcgt
    14221 gattttgcaa tacacttgct ggcaaatgat tcgttacagg tccttcaatc atccctttga
    14281 ttgcatcagc tttgctttcg ccaaatgcca tcaagacgat ttctttactt ttcataattg
    14341 aaccgattcc cattgaaaca gcttttgttg gtacatcttc tgctttatcg aagaatcgtt
    14401 tgtttgcatt gattgttgat tctgttaagt caactactga agtcgttccg tcaaatgaag
    14461 caccaggttc attgaaaccg atatgtccat tttgcccgat tcctaagatt tggatatcga
    14521 ttggatgtgc atcgatgatt tgatcatact ttttgcatgc tgcttccaga tcttctgctt
    14581 ttccatctgg tacaaacgtt tctttgaatg gttttttatc aaataattgg acatccatga
    14641 aatgacggta gctttgttca tctgaaccgc ctagtccaac gtactcatct aagtttacag
    14701 aagtcatttc actgaaatcc aaatcgcttg aagtcatttc tttatataaa gtaactggtg
    14761 tgcttcctgt tgccaatcct aatacttttg cacctttgtt cataccttct ttgatgattt
    14821 caaatgcttt ttttccgcct tcttcagcgt tttttacacg aatgatttcc atagtgattg
    14881 ctcctttata ttttggtata gcccaattat agcattcttt ttttcttttt acaataatta
    14941 gtatagacca aattgcattt ttttcatttt cttgacaata aataggaatc cgtgttaggt
    15001 ttcataagat ggttcaatca aacaatccat gttgcatgaa aaccaagcaa gtgattcact
    15061 gtggacgctt tatgtctgca gtttttttat gaaaaaggag ttattatgag tatactgaca
    15121 ttaaacaaca ttacccagca atttggcgac aaaatcctct atgaaggtgt cgatctgcaa
    15181 ttaaatgctg gcgaacatct tgggctgatt ggacaaaacg gagccggtaa aagtacattg
    15241 attaaaatca tcactggtga gatcttacca gatgacggac agatccattg gcaaaaaaat
    15301 attcacaaag gttacctcga tcaatatgtg gaagtcgatg aaacattaac aatcgaagaa
    15361 tttctaaaaa ctgcgtacgc aaaagaatac gaaaaggaag aaaaaattgc ttttctttac
    15421 caaacatata gcgagacctt cgatgattcc ttgctggaaa aagctgggaa actccaaacg
    15481 gaattagacc aaggagtgtt ttatcaaatc gacaccttag ttgctgagat gagcagcggg
    15541 ttggggatcg atgtcttagg tttagattca ctgttgaaaa atctaagtgg tggacaacgt
    15601 tcaaaggtga ttttagcaaa actactttta gaaaacccag atgttctgat cttagatgaa
    15661 ccaaccaatc acttagatga tcagcatatc caatggctga cgcagtttct tcaggatttt
    15721 gacggtgcgt atatcgtgat ttcccatgac caagaatttc ttgatcagat caccacccat
    15781 atcgcagaca tcgagtttgg aaagattact aagtatactg gccatctaaa acaagcattg
    15841 aaacaaaagg aacaaaatcg cgaaagctat ttgcgccaat atcatgctca acaaaaacaa
    15901 atcgaaaaga ccgaagctta tattcgaaaa tacaaagccg gttcccgatc aacgatggca
    15961 aaaagccgac aaaaacaatt agataaaatc gaacggctga cgcctccagc ttcagcaagt
    16021 aaagctgtct ttgattttcc attctcgcct attgtcacga cattagcagt ggaaacaact
    16081 gatttagtca tcggatatga tcgaccgcta cttgcaccca tcaatttgac catccgcttt
    16141 ggtgaaaata ttgccattcg aggcttcaac gggattggaa aatctacttt attaaaaaca
    16201 ctgatcggtg agattgaaaa aataagtggc gatttccact tcccagataa cacaaaaatc
    16261 aattactttt cacaagatct gtactgggaa aatccattag aaacaccact acaatattta
    16321 agcagtcaat ttccaaaagc gactatcaaa gaattacgtc gccaactagc taaagcaggg
    16381 ttagttaatc aattagcaag tgaacctctc actacattaa gtggtgggga acaaactaag
    16441 gtgaaacttg cacagttgac aatgaaccaa ggtaatttac tgattctcga tgaaccgacg
    16501 aaccatatcg atcaagaaac gaaagaaagc ttacaagacg ggatacagaa atttccagga
    16561 acagtaatca tcgtctctca tgaacaagaa ttttatcaag atcttgtgca acgagtcatt
    16621 gagattgaac caaaataaac gtttgattga atagttgaaa aaaaggagct gtgacaaaag
    16681 ttttgtcaca actccttctt ctgaataaat ggtggccaat tagctgacct tcggtattag
    16741 ctcaaaaaac ggcaaaatat gaggagctat ttttatttgg ctattcttat tacttgatgc
    16801 agaacagctt ttcacaacct cttttcgtct attttttatt ttcgagattt ctctttcctt
    16861 taaaaacaac tgtttgaaag aagaacgcac atccttgaaa aacaagcccg ctaaccgtta
    16921 cacctaacca gccatactgc tgccacattg tcgtccctag caatgaacca gccgcacctc
    16981 caataaagta cataaacata aataca
//
LOCUS       DAYYEF010000056        16271 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000056 DAYYEF010000000
VERSION     DAYYEF010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.059"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(161..445)
                     /locus_tag="ACHA1B_002186"
     CDS             complement(161..445)
                     /locus_tag="ACHA1B_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702935.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="ACHA1B_002187"
     CDS             complement(463..1353)
                     /locus_tag="ACHA1B_002187"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YicC/YloC family endoribonuclease"
                     /protein_id="HFM8702936.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="ACHA1B_002188"
     CDS             complement(1373..1591)
                     /locus_tag="ACHA1B_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HFM8702937.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="ACHA1B_002189"
     CDS             complement(1561..3261)
                     /locus_tag="ACHA1B_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HFM8702938.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="ACHA1B_002190"
     CDS             3528..4301
                     /locus_tag="ACHA1B_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702939.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="ACHA1B_002191"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="ACHA1B_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015234 - thiamine transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015888 - thiamine transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HFM8702940.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="ACHA1B_002192"
     CDS             complement(5125..6096)
                     /locus_tag="ACHA1B_002192"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004749 - ribose phosphate diphosphokinase
                     activity [Evidence IEA];
                     GO_process: GO:0009156 - ribonucleoside monophosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HFM8702941.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="ACHA1B_002193"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="ACHA1B_002193"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003977 - UDP-N-acetylglucosamine
                     diphosphorylase activity [Evidence IEA];
                     GO_function: GO:0019134 - glucosamine-1-phosphate
                     N-acetyltransferase activity [Evidence IEA];
                     GO_process: GO:0006048 - UDP-N-acetylglucosamine
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HFM8702942.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="ACHA1B_002194"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="ACHA1B_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0045982 - negative regulation of purine
                     nucleobase metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HFM8702943.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="ACHA1B_002195"
     CDS             complement(9051..9875)
                     /locus_tag="ACHA1B_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HFM8702944.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="ACHA1B_002196"
     CDS             complement(9848..10528)
                     /locus_tag="ACHA1B_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HFM8702945.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="ACHA1B_002197"
     CDS             complement(10551..11489)
                     /locus_tag="ACHA1B_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HFM8702946.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12585)
                     /gene="ispE"
                     /locus_tag="ACHA1B_002198"
     CDS             complement(11734..12585)
                     /gene="ispE"
                     /locus_tag="ACHA1B_002198"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050515 - 4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase activity
                     [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HFM8702947.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="ACHA1B_002199"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="ACHA1B_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HFM8702948.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="ACHA1B_002200"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="ACHA1B_002200"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA];
                     GO_process: GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HFM8702949.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
BASE COUNT         4764 a         3483 c         2789 g         5235 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg t
//
LOCUS       DAYYEF010000057        16163 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000057 DAYYEF010000000
VERSION     DAYYEF010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16163
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.060"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..420
                     /gene="scm"
                     /locus_tag="ACHA1B_002201"
     CDS             <1..420
                     /gene="scm"
                     /locus_tag="ACHA1B_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HFM8702950.1"
                     /translation="STDTSASSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSS
                     TTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKR
                     ALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
     gene            complement(575..1561)
                     /locus_tag="ACHA1B_002202"
     CDS             complement(575..1561)
                     /locus_tag="ACHA1B_002202"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HFM8702951.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1584..2150)
                     /locus_tag="ACHA1B_002203"
     CDS             complement(1584..2150)
                     /locus_tag="ACHA1B_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HFM8702952.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2164..2580)
                     /locus_tag="ACHA1B_002204"
     CDS             complement(2164..2580)
                     /locus_tag="ACHA1B_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HFM8702953.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3037..4971)
                     /locus_tag="ACHA1B_002205"
     CDS             complement(3037..4971)
                     /locus_tag="ACHA1B_002205"
                     /EC_number="1.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFM8702954.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5273..6208
                     /gene="pplA"
                     /locus_tag="ACHA1B_002206"
     CDS             5273..6208
                     /gene="pplA"
                     /locus_tag="ACHA1B_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular electron transfer flavoprotein
                     PplA"
                     /protein_id="HFM8702955.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6298..7401
                     /locus_tag="ACHA1B_002207"
     CDS             6298..7401
                     /locus_tag="ACHA1B_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0017013 - protein flavinylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HFM8702956.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7414..8367
                     /gene="menA"
                     /locus_tag="ACHA1B_002208"
     CDS             7414..8367
                     /gene="menA"
                     /locus_tag="ACHA1B_002208"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HFM8702957.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFTMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9181..10527)
                     /gene="gor"
                     /locus_tag="ACHA1B_002209"
     CDS             complement(9181..10527)
                     /gene="gor"
                     /locus_tag="ACHA1B_002209"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004362 - glutathione-disulfide reductase
                     (NADPH) activity [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006749 - glutathione metabolic process
                     [Evidence IEA];
                     GO_process: GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HFM8702958.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10661..11914)
                     /locus_tag="ACHA1B_002210"
     CDS             complement(10661..11914)
                     /locus_tag="ACHA1B_002210"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:1901576 - obsolete organic substance
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HFM8702959.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(11920..12843)
                     /locus_tag="ACHA1B_002211"
     CDS             complement(11920..12843)
                     /locus_tag="ACHA1B_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase U32 family protein"
                     /protein_id="HFM8702960.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13064..15556)
                     /locus_tag="ACHA1B_002212"
     CDS             complement(13064..15556)
                     /locus_tag="ACHA1B_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HFM8702961.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15563..16030)
                     /locus_tag="ACHA1B_002213"
     CDS             complement(15563..16030)
                     /locus_tag="ACHA1B_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HFM8702962.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
BASE COUNT         4747 a         3377 c         2873 g         5166 t
ORIGIN      
        1 agcacggaca cgtcagcttc aagtgacagt acagatacta cctctaccac aagtgatagc
       61 tcagattcat ctaccactac aagtgatagc acggacacgt cagcttcaag tgacagtaca
      121 gatacatcct ctaccacaag tgatagctca gattcatcaa cttcaagcga tagtacagac
      181 acgtcgtcta ccacaagcga tacacgtcat gcaagtgtct ccttctcaaa aacaagttcg
      241 gataacagga cgaactttaa cttaactaat aaaacaagca atgacaatgg aaacaaatca
      301 aaaagagcac ttcctaaaac tggaagtcaa tcgaataatt ggataacact cgcaggcgtt
      361 atattacttg taatcggttt aagaatcact tttatgagtt ataagaaatc gaaaaggtaa
      421 aaaaatattc aagataaaaa agagcaacgt cgctaacgga cgttgctctt tatttttgct
      481 ttttatcata aatacaagaa ctacaattca atttgtcaaa aaacacgtag atttccttct
      541 gagaaattta tttacgtatc gaacctttcc ctattcagtc tttgcgatcc aaaatcagtt
      601 gggtaaggga aaagagattc tcttttgttc gaagagaggt ggcaggtaat ttctttattt
      661 ccttcaaagc cttttctgtg taagaggccg ctaacttcct agcttcttcc acgcctcctg
      721 tatgttcaac gattttgcgt acggcgtcga catcttcttc tgtcattgcc gctttcttct
      781 ctaaataagg tagtagcttt ggtttgtttt tttgcaaaga gtagatcaac ggtaaagaat
      841 agaccccttg acgcatgtct tctagtacag gtttgccgat ttcctggctc tcttttgtat
      901 aatctaaaat atcatcgata atctgaaagg ccatcccgat agaaagtccg atatctcctg
      961 ctttttttgc gaagcgctcg cttgttccac tttcaaaagc gccaacagaa caacttaatt
     1021 ggaacagttc agctgtctta cctgaaatat tttccaaata ttcttttaca gaaagttcat
     1081 aattatagcg atcatccatc tgccctaatt cgccattcaa tactttttcc atactgcgag
     1141 aattcaattg gagacttttc aaggaagtgg agtaatcaga caatagttta aaacagcaga
     1201 caaataaata gtctcctgca tagacagaaa cgacattacc aaactgacta cggatattag
     1261 gctgaccacg tcgcagatcc gcttcatcaa cgatatcatc atggatcagt gtggccgtat
     1321 ggagcatttc gatagaagct gccaaagcga tggctttgtc tcgatcttgc tctggtccaa
     1381 attgtgagaa caatagctga taggcaggac gcaacagctt tccgccggca tggatcgttt
     1441 ctttgattgc ttgttcgaca ggtttgtttt tcaggcggac agtttcttcc atccgtttta
     1501 gtgtttctgt caattcttta cttaaagcag gatagttttc ccacattgga tgtagcttca
     1561 taaaaaaact ccttgtgtga cgattatttt ttggtaaaca ttgggctcca tttttgtttg
     1621 gttccctgct cataatcttt ttggaatcgt tgaagtgtct gcacatgtcg taaaagataa
     1681 ttcgctgcga tcccgattgc aatccctgat aaaatcccta aaactgaaag gactggcaag
     1741 tacaacatga ctgtccatga ttgtgcaatg aaagaagcca tcaaaagctg tccgacatta
     1801 tgcatgaaac cgccggccgc actaattccg atgatactga cacgttttgg tcctaattgc
     1861 ttgaccaata acattccaaa ataactaagc aaagcaccac tcatactata aaggaatgtg
     1921 gaaatcgttc cgcctagcaa agtagtcagg aatagtcgta gccaaagtag taagaagctg
     1981 tcttgttttt tcatggtaaa aatggcaacg atcgtgatta gattggctaa gcctagtttt
     2041 gcaccaggcg caaaagaaaa aggataaggg atcatatttt ccaataaacc aatgatcact
     2101 ccttgtgcaa caagtagcga aatataaatc attttttgta atttactcat ggtgtgtaaa
     2161 ggtctaataa atcagactgt cttcgtcacc tccatctgtt gaacggactt cgatcactaa
     2221 tttatgtggc aaacagacga tggtttcgcc atttttcgtt gcccagcctc gacgtacgca
     2281 gatctggtca tcgcaatctg cttcttttat ccgtactcga tcgccatcta tctcgatcaa
     2341 gttataatct ccgtgttcat ctttgtaagt atatgtgttg ctctcttctc cagccatcaa
     2401 agggaatgtt ttgatttctg tgccatccac acgcagtacc gcttcttttt ctgctgttgc
     2461 ggtgttttgc tgaagaccaa aaatcatgac tggtaaaaaa gaaagaacag tcaaaagcaa
     2521 aataataaaa acatcccaag gtttgagcag acttttttca gcaaattctt taaggctcat
     2581 ttttgttctc ctttttccag attaactcac ccaattttag cataaaaaca agaggttgtg
     2641 acacctgtgt cttgctttga gtaataagaa cgaagaatag aaaacagctt tccatgtttt
     2701 ctaattcttt gggcttatta ccgagaagca gcaggtggaa caccgtttat aacaagaggt
     2761 tgtgacagaa gtgggcaact tcaagaaata agaaggaatt tacgaaaatt acttttcaag
     2821 tttttgtgaa atttcggctt atttttcgaa gaagctactt ctggaacacc gtttataaca
     2881 agaggttgta acagaggttg tgacacctgt gtcttgctca tggaggctta tctcgggcat
     2941 cttattcctt taattttaca taaaaaggag gctgtgacgg tttgtctcag cccctttcta
     3001 ttgaaatctt gcattcaaat aacgttcttt atctatttat ttcttgccgt actgggaact
     3061 tggtctaccg taccaccaat tacctagtgt acgttgtagc catggaatta cccagcgatc
     3121 caacccaatc gcacgtccgg aaccgttcat caatgcgaaa gcaacaaaaa tgaaccaaat
     3181 gtttacccag taaaacatgc ctgataagca gaacgtgatc accaatacaa tcgttgtcgc
     3241 actgcatagc catgtgaata atccagcaat caatgctaat gccaaggcaa tttcaaagaa
     3301 taccatgaat ttttggaaga acattgctac atcattgttt ggcatgatca cttgcatgat
     3361 ctttgtgaac cagtctggtg acttctcaat cacagccatt ggttcttcac cgtatgcata
     3421 actcaaacca aaatgtgcag cttgagtcgc tgcttctccg gcacttgccc ctgctccgct
     3481 ggcagctgtg gttgcatcac cagcagcaga agcaccactg gcaacatctg ttacattgta
     3541 ttcccatgtc caagggaaca cactgtttcc agtgaaccat gatccttcac caaaccaagt
     3601 acttggtttg aacacttcac cattcccaat gatttttttg gaagcttcaa cgaaccaaac
     3661 taaaccatag aaaatacgaa gtggcacact ccataagaca ttgccgtaac gagaagaatg
     3721 tcctcgagtc acgttgcgat catctttgat atggaaaaac tcatgcatta aatattggaa
     3781 catataataa ccagaacgaa tatcaaagaa gtatttcaaa ttcacgatat gtttcattac
     3841 gatagctaaa aatccgctta aatggatctt atcaaatagg ttagctaccc cccatttggc
     3901 accaatagaa accataaatc cttgatagtt tcctttaaat ttatgctttt ctccgccttt
     3961 gatcgaagcc acgatattcg ctgcggctgt gtgtcctgtt tgttcagcag cttgaacgat
     4021 ctgcggtgtc ggtgttcctg ggaattcttc ataaaagact aaatcaccaa tgatatagat
     4081 gtttttatct tcgtagcctt ttgcctgcat atattcattg gcgatcaacc gctgtccgcg
     4141 tgctgattct aatccaaagt cagcagcgtc agaagttcct ttgacaccag ctgtccaaat
     4201 cagtgtgtga gtcggaatgt tgcgtccgtc tttcaatttg atatgatcag cagccacttc
     4261 tacgattggt gcattcaata ataattccac gttgtgctta cgcaaatagc gttcagcttt
     4321 tgcagcatca tttcgatcca acatattcaa gatcgtcggc attgcctcta cgaccatcag
     4381 tgtgatttcg tttggatcta atttataatc tttggctagg cgatttttcc agtcgatcag
     4441 ttccccaatc atttcaatac cggtaaatcc agaaccacag acaacgaaag tcagcatggc
     4501 tttacgcagt tcatcatctg gttccaatgc agcttttgct actgtcttct caatatgttc
     4561 ccgaatcctt acagaatctt caaatgacca aagggtgaat ccgtgtgctt tgacaccagg
     4621 tgtaccaaag tcattcggct ctccgcccat tccaaggatc agctgatcaa aaggatagga
     4681 acctaatttg gtcttgacga tttttcgttc tttatcgata ccgattacag tgtctgtgac
     4741 aagttgtaca ttcttttgac gagcaaacaa atgctgcaga tcgtattgga ttgcttctgg
     4801 ttctacacgt ccgccagcta cttcatgcaa ctcggtcatc atagtatggt acgaatgacg
     4861 atcgatcaga gtaattgcta catcttcttt tttcagtttc tttgccaagt attttgtagc
     4921 tgaaacaccg gcatatcctg ctcctacaac gacaatattt tgctttgcca ttgatcatcc
     4981 gctccttata gactatctat ataatgaata tatgataatt cttttagttt gatacttatt
     5041 acacaatctc catatattat atagatgttc tgttcttttg tctaactcct tttggatttt
     5101 tttcaaattt taaaataaag cgttttttca cgaaatttgc tgaaagaaaa cgtttgaaat
     5161 attacatggg ttatttatca aaaatagttg acttataggc taaaaagatt agaatgtata
     5221 atgaatcaca aagaaaaatt gtggactaga aatggaatgg tggggtatta aaatgaagaa
     5281 aaaacgtttt gtaactggat ttgccgtatt agcattttca gctctagtgt taggcgcttg
     5341 cggcgcagat gacaacggaa gctcaaactc ttcttctgaa tcatctacag cacaatcttc
     5401 gactgcaaaa agcacaacag aatcatctgc aaaagttgta gctggcggag atttgcaaga
     5461 cggcacatat aaattagaag aaaaaaatta ttcaaatggt taccgtgcag tctttgaaat
     5521 ggttgtaaaa gacggcaaaa tcactgaatc aaaatatgat aacgtcaatg aaaacggcga
     5581 atcaaaaaca aaagatgcag aatacaacaa aaacatggaa gcaaaatctg gcacaaaccc
     5641 agaaaaatac attcctgagt tgaatgacca attcttaaaa gcacaaagcg caagcggtgt
     5701 ggaagtcgta actggagcta ctcactcatc tgaaagcttc caaaactacg cacaacaatt
     5761 gatccaagct gctcaagctg gtaacacaga tacaatcgaa atcgacaatg gtgctgattt
     5821 gaaagacggc acttacaagc ttgaagaaaa gaactactct aacggctacc gtgtgcaatt
     5881 cgaaatgaca gttgctggcg gcaaagtaac tgaatcaaac tttgattata tcgacaaaga
     5941 cggtaaatca aaacaagatg atacagaata taatgaaaat atgaaagcaa aaagcggtac
     6001 agaaccaaaa acttacatcc ctactctgaa cgacgaattc gtcaaagcaa tgggcgaaga
     6061 agatggctca cctgctaatg tagaagttgt tacaggtgct acacacagct cacattcatt
     6121 catcatgtac gcacaacaat tagtgaatgc agctgaaaaa ggcgacactc aaacaatcga
     6181 agtagataat atcgtaacag aaaaataatc acataatcat actaataaaa gttggagggt
     6241 gggacgatag ccagattagg cagtcgtctc acctttcaaa atgaagagag gaaaaagatg
     6301 cggaaaaaac tactattttc cttaatcaca ctgggcatct cttttatggt gctaactggc
     6361 tgcagcaact cagcaaataa aacaaccact gaaagttcag cagctaccaa gatattgaaa
     6421 gatccatatt ctgatgaaca gttcttgtta gggacttacg ttcgtatccg tgtgtatgat
     6481 gaaggcaaag aatcagcatt gaaacctgcc ttcgatcgag taaaagaact tggtgataaa
     6541 atcacgatca atcaaaaagg ttctgagatc gatgaagtga atgagcaagc tgggatcaaa
     6601 ccagtaaaag tttctgatga cgtctacacg ttagtcaagc gggcctacga atatagccaa
     6661 gattctcaag gcggattcga tatggcgatt ggtgcaatca cacaattatg gcgaatcggt
     6721 tttgatgacg ccagaaaacc ttcccaagaa gaaatcgatc aggcattgaa attagtggat
     6781 tatcataaga tcgaactaaa tgacaaagaa aaaactgttt atctaaaaga aaaaggaatg
     6841 atcatcgatt taggtgcaat cgccaaaggt tacattacgg acgaagtagt gaaagtcttg
     6901 aaaaaacaag gagtgaccac tgccatcgtt gacttgggcg gtaatgtcta tgtcttaggc
     6961 cacagcccaa gaggcgaaaa ccaagactgg acagtcggca tccaagatcc gaacatggct
     7021 cgcggatctg ttttaggttc tattaaagaa cggaacaaaa cattagttac ctctggaatt
     7081 tacgagcgtt atttagaagt agatggcaaa aaataccatc atttgtttga tccaaaaacg
     7141 ggttatccgt tcgacaatga tatcgcaagt gtcacgatca taacagataa atcaattgat
     7201 ggtgacgggt tgtctacagc agtcttttca atgggtgtga aaaaaggact ggaatacgtc
     7261 gaaagcgaat tgaataacgg gacggaagcg atcttcgtga caaaagacga taaagtatat
     7321 gtgaccgatc caatcaaaga caccttcaaa ttatcggagg actcccatta cacgatgggt
     7381 gaccgttctg aactaaaata aggagtacga accatgacac taaaaatctt tttagaagta
     7441 gttgaaatac gaacaaaggt ggctagtgta tttccttttg cggtaggggt attattctct
     7501 atcgcttttt ttcatgagat acattggcta aacacttttt tattttttat tggaatgcta
     7561 gtttttgatt tagcgactac cgctatcaat aattacatgg attatgaaaa ggctcattct
     7621 gaagtatata agtatgaaga aaatgtcatt ggccgcagaa atctatctcc tgtattgatt
     7681 cgaaacatga ttttagctat gattgcattt gtttttgtta tcggcgttat tctaacgatc
     7741 aatacgggtt ggcttttact tttgatggga tttatctgtt gttttattgg agtattctat
     7801 acattcggac cgattccttt atctcgaatg cctttagggg aaattttcag tggggtgact
     7861 atgggccttg gaatttttac catggtcgtt tatgtcaata cattcggttc agatgtctat
     7921 gatctgacag tcaacttttc atctggacaa tttgctttgg taggaaatct ttgggctata
     7981 gcagcaatcg tattagcttc cttacccttg gtgtttacga ttgccaatat catgttggct
     8041 aataatttgc gggatcttga ccgtgatatt gaaaatcatc gctatacact agttttttat
     8101 atcggacgtc ctgcgggaac agtcttattc cagctattga tgtatgcttg ctatttcgtg
     8161 attttaatgg ggttgttgag cggtatctat gaatggccga tcttggtcac cttcttgacc
     8221 ttgccaattg tgaagaagca tttggatcaa ttcaagcaaa cgttacccca gcctatcagt
     8281 ttcagctatt ccatcaaaaa tatggtctta ttcaatgcca gttatgtatt ggggctatta
     8341 ctaacaatca ttatgcaagc catttaacag catgaagagg ttgtgaaaaa actgccctgc
     8401 atcaagtaat aagaacagcc aaataaaaat agctccttat atttttcgtt tggttgggct
     8461 tattaccgca gatgcaagct tttgaacacc gtttatcagg aggttgtgaa aaagtcgctt
     8521 agtttcgagt attaagaaaa attttgtgaa aatggctttc cacatttttg cataaatttg
     8581 gcttaatacc gagaaactgg cttttgaaca ccgtttatca gaggttgtaa aatcagtgtt
     8641 ttgtcctgag tattagagaa acaaatggaa aaatagttcc tcatattttg ccgttttttg
     8701 agctaatacc gaaggacagc tgattgaaca ctatttgttc ggaaaaagtg actaactatg
     8761 acacaatttt tttcacagtc ccttttttca cttgatttga ttcgtaccag cgaacttgac
     8821 gagaactttc ttggtttggt aactatatgg tattctttta acatcctcgt ttgcttcttc
     8881 taatttattt atacaaagtc acactttttt aaacatctgt tcttcgatac atttctattt
     8941 cttttaaaca tcgataccaa tattttgaac ttaagagtgc ataccaaatg gattcattta
     9001 ctcttcgtca gttacgaaga taatcaaaat ctccaacttc cctacttatt tcgttttgag
     9061 aattatcgaa gcaatcttac ataaataact aaaaaacaaa aaaccagaaa atcagtatac
     9121 tgattttctg gttttacatg gtttgttcaa taaaaagctg ttggaactgt taatattaaa
     9181 ttatcgcatc gttacgaatt cttccgctcc tgttggatgg atggctactg tattgtcaaa
     9241 gtcttcttta gttgcaccca tcttgatagc cacggcaaaa ccttgcagca tctcatcgac
     9301 accaacacca atagcatgta agccgacgat tctttcttct tttccgacac agatcaattt
     9361 catttcgcat ttttggcgat aatcatttaa tgcaaagtac attggggtaa agcgtgaacg
     9421 ataaactttc aattcatttt cgccatattt ttccaatgct tcttcttctg tcaaaccaat
     9481 tgttgcaatt ggtggatgcg taaagacgac tgtcggaaca agtttatagt caagataaga
     9541 atctttcttt ccattaaata aacgttctga taaacgtcta ccagctgcga ttgcaacagg
     9601 agtcagatct aatttaccga tcacatcacc aacagcaaaa atatgttcat ccgttgtatt
     9661 ttggtattta tctactttga taaacccttt tttgtccaat tccacatttg tattttccag
     9721 acctaatttt tcggtattcg gtacacgtcc accggcaaaa agtacacaat caccagttaa
     9781 ggtttcacca ttttcaaata gcaccgtata ttcgtcattg tttttagtaa tttctttagc
     9841 aatatgatgt gcgtaagttt ttattccagc ttcttggtac atttggatca aattgtccga
     9901 aagcatttta tcaaacgttc taagtggtcg ttcttttcga tatgcccaca tgacttcact
     9961 acctaaacca cgaaatacac ctgaaagttc agccgcaatg tatccagcac ctaaaacgat
    10021 tgctctctta ggtaactctg ttaattcaaa aaatccattt gaatcaattg cgtattctcc
    10081 accaggaatg gtcattttac ttgcacggcc tccagtagcg atcaagattt taggagcacg
    10141 ataggtttca ccgtttactt cgatcgtttg actatcgata aaagtagcgt aaccttttat
    10201 agcctcgaca tgattgctat ctaatcctct ttgataagca ccgtgtagaa aatcaatata
    10261 tttttctcgt ctttctacta gaccggcgaa atcaacattt tttaaatctg cttggatacc
    10321 gtaacttgag gcatctcgtt caattgtttc caaaatcgta cttgcttgcc acataacttt
    10381 tttaggtaca caaccgacgt tgacacatgt tccgcccaat tcattcgctt caatcagcaa
    10441 aacttttgcg ccatgcatcc ctgctctgtt tgctgaagca ataccgccag agccgccacc
    10501 aattacgatg taatcatata tttgcatttt gttcctcctt attgaagaga tcaatcaaaa
    10561 cctttattta acgatccttt ttctacagaa aacaagtgta acacttttct tgaattttgt
    10621 atgcgaagat gcttaaaaca gggatatatc agctttttcc ttatttacgt tttcggatca
    10681 tatctccagg tttcaccggc tgtgcgactg gcatagttaa aatcatcatt ggatttggtg
    10741 ctcggtcaat ggattcgcct tcttcattat gcataacttc aacggtttga ctgaaatgac
    10801 tgaatcctgg accataaaat tcgatttcat ctcctacaga aaacaagttt ctctgacgta
    10861 tcgtagcaat ctgtgttgcc tcatcataag ataatacttc accgacaaat ttatatactg
    10921 ggattttacg acgttcaccg aataattgtt cgttttcagt tggtgtattg tagtaaaaac
    10981 ctgtagctaa ttctcgttgt gctactttcc ataactcgtc gatccattct tgcttgcaga
    11041 catagttttc aggatcttcc atataactgt ctacagccgc tttatagaca tttgacaccg
    11101 tagatacata atggatcgat ttcattcttc cttcgatctt gaagctgtct acgccgtttt
    11161 caatcaattc tggaatatgt tcgatcattg acatatccac tgcactcatc gagaattctt
    11221 cttccacttc gcctgtatca gttaaactgt ttcgttcttg accaaaaggc atatcgaaca
    11281 atccatactt ccagcgacaa gattgagaac atccgccacg gtttgcatcc cgcatcgaca
    11341 tatggttgga caatgtgcat cgaccagaat aagagataca catggcacca tggataaatg
    11401 cttcgatttc ggtatccgta tttttacgaa tctctgccac ttcctccatt gaaacttcac
    11461 gagctaaaac gacacgttcc aacccttctt ctttccagaa ttccaatgtc tcaaaattag
    11521 ttgctgaagc ttgagtggat aaatggatcg gcagacctgg ggcttctgtc gcacaaattt
    11581 cgatcaaagc tggatcagaa acaatcactg cagaaatacc gacatcacgc aaactgcgga
    11641 aaaattcccc tgctccatct tcatttcctt catgggtgac catattagca gcaacgtata
    11701 ccttcgcatc atgttctttt gcaaaagcaa ctccttcagc catttcttca taagtaaaat
    11761 tacctgcacg gcttcttaaa ccatatgcat tcccgccaat atatactgca tctgctccat
    11821 aatggatcgc ggtttttaac ttttccagtg ttcctgctgg cgctaggatt tctggtcgtt
    11881 tcaattttct ttttactgtc atttctttca tcatactcct tatttgatag cagaaggatc
    11941 aatataaaag aatcctgtat ctaattcacg gttttcagga tgcaatttac tgatttcgct
    12001 agtcattttt tccgcttttt cttgatccca gctaccttct aaaatttgtt tttttgcttc
    12061 ggcgaatagt cgagtgatgt ttacgaattt ttcgcctgga gtaaataatc cgtccaattt
    12121 ccatgtacag taatgatgct gataaagttc attcaattca ttcgagagat tcagatcatt
    12181 gctggcaaaa atatgtgtgc catgactatc ttcataaata gaataatgtg tctcttcttt
    12241 tttaggttcc gagataaaaa gacctctttc acgatctttt tgttcgtctt gtttcgtata
    12301 gttatagtaa ttctgtagca gtggacgttt ggattgatgg atgcatgtag caccatacac
    12361 aagggtttct acaggaatat cgagtttttc ttccatcgcc ttcatctctt caaaaggaac
    12421 ttcacgagca agtactgctc caactgcgcc ttttttcgcc cagaaattga tttgacgtgc
    12481 gctcgttact aatgtttcag catcataaat atacggtata cgcaattcag gatttttttt
    12541 catcgtataa ataatacctg tatcaccaac tgtgatcaca tctacgttta tttcttttaa
    12601 aaaagccaaa tattcaggta catttttcat tttttcagga tgaatgatcc catttacagc
    12661 aatattcgct tttttaccat acttgtgtgc taattctacc aattgtcgct gttcttctcg
    12721 tgtaaatgaa gcaggcagac gcaatccaaa ttgctcttca ccgaaatata gtgtatctgc
    12781 acctgcagca agcaactgtt ctgcttgttc aatagtttct actgtggtta tgagttcgat
    12841 cataattttc tcctcctaca acttcataat agtagcatag ctctaaaaac tttccaatac
    12901 ttcttctatt taaagtcgga tttttgaaaa ttatttcaca aaaaatcaaa ataaagttcg
    12961 atatattctg tccaaatata aaaagagatt gtgacaaaaa tcttgtcaca acctcttaat
    13021 caagtcttac tattataaaa attcagctac acaggccaag taactatagg gaacctactg
    13081 tttccttttt aggtccgcga acattcaatg tgatcttacc ttttgaagca cctactgtta
    13141 cgtggtcacc taaacgaatt tctccgccaa gcaaagcctc gctcaatcga tcttcaattt
    13201 ctttttgaag tgcgcgacgg attggacgtg caccatattc aggatcaaat ccagctttcc
    13261 cgatcacatc gattgcagat ggtgtgattt tcacttgaat atcttgttct ttcaatcgtt
    13321 tgataatcgc tttgctcatg atttggacga ttgtatggat ttcatcttta ctcaatgaat
    13381 ggaagacgac agtctcatcg attcgattca agaattcagg tcggaaagct ttctttaact
    13441 cttctaagat acgtttttgc atggctttgt gatctttagt aacatcttgg acattgaatc
    13501 cgacattttt ttcttctcga atttgtgtcg ctccgatatt tgaagtcata atcatgattg
    13561 tatttctaaa gtccactttt ctacctttag aatctgttaa atgaccatca tccaatactt
    13621 gcagaagtaa attgaaaacg tctggatgtg ctttctccac ttcatctaag agaatcactg
    13681 aatatggttt ttgacgaatt ttttctgtca actgtccacc ttcatcatac cctacgtatc
    13741 ctggaggaga cccgattaat cggcttgtac tgtatttttc cataaattct gacatatcaa
    13801 cacggatcag ggcatcttca cttccaaaca tgacttctga aagtgctttg gccaattctg
    13861 tttttccgac accagttggt ccaaggaaca tgaatgaacc aattggacga tcaggatctt
    13921 tcaatccgct tcgtgcacgg cggatcgcac gtgaaactgc tttgacagcc tcatcttgac
    13981 caacgacacg ttcatgcaga agtccttcca gttctaacaa gcgttcgctt tcttttttct
    14041 ccaactgctg tagagggaca ccagtccact ccgatacaac tgtagcaaca tcttcttctg
    14101 ttacacgatc agaataacct tgctcctgtt ttgcttcaat tgcagaaact ttttgcagct
    14161 ttttacgtag tgctttttct tgtctgcgta attgagcagc attttcaaag tcttgttttt
    14221 ggatcgctgc ttccttttct tgtactagtt catcgatttc tagtttgatc acagttgatt
    14281 ttgttaagtg atcggtttga tccaaacgga ctttcgctgc tgattcatcg atcaaatcaa
    14341 ttgctttatc gggtagttga cgagaagtga tataacgaac agaaagattg actgctgctc
    14401 gtacagcttc atctgtgatc tccactccat ggtgctcttc atatcttgta cgtaatcctt
    14461 gaagaatcac ttctgcttct tcaggagttg gctcatctac ttgaatgcga gcaaaacgtc
    14521 gctctaatgc agaatctttt tcgatatatt tttgatattc atctagggtc gttgctccga
    14581 tcgtttgtaa ttctcctcga gctaacgccg gtttcaagat attcgaagca tcaattgctc
    14641 cttctgctcc acctgcacca attaaggtat gcaattcatc aatgaataag attacttgac
    14701 catcattata gatttcgtcg atgacctttt tcattcgatc ttcaaattca ccgcgatatt
    14761 tcgtaccagc aaccaaagat cccatatcaa gcatcatcag gcgcttttct tgcatgtctt
    14821 ctggcacttc acctaaaatg attttttgag ctaacccttc agcaatggct gttttgccta
    14881 caccaggttc acccaccagt acagggttat tctttgtccg tcggctaaga atctggataa
    14941 gccgtttcac ttctctcgaa cgaccaacaa ctgggtccag cttgttttct tttgctaatt
    15001 tcgtcaaatc acgtgctaat gaatctagcg taggtgttcc ttgcggtgtt tgccgtttat
    15061 cttgtacatt tacatttcta cgacgattca ttccttttcc agcagaatca ccagctagcc
    15121 ccattttttg tttcagaact tgacgggctt ttgaaaggct gatacctaag ttgatcatga
    15181 ttcgagtagc catgatactt tcatctttta ataagctcat caaaatatgt tctgttccaa
    15241 ctttttgaga accagttttc ttcacttcgc tgctagctaa agcaaaaact tgtttcattc
    15301 ttggtgaata tggaagaaag actcctttag ggtaagaacg gataccacca taaccaatca
    15361 gatgttcaat ttcttcataa atttccgttt cattcaaatc catttcacgt aatacttttc
    15421 cagcaattcc attttgctcg accactaagg ctagtaaaac atgttctgaa ctaactgatt
    15481 gatgtttcaa ccgttttgct tcttcttgtg caatttctaa tactgcttgg gctctttcag
    15541 taaaaagttc ttccatctaa tctcacttcc catcttcata acttaaacgt tccagaaatg
    15601 ctcggagaat ccgagcacgt gtatgatctt catattcatt gaaattcaat gtgttttttg
    15661 caattgcact caacatcaag tttccttctt tttttgtaat tatttggtct tcataaagtt
    15721 tttgaataat agcaaaagca tttttctcac tgattgtatc atcaaataac tgatttatct
    15781 gctcaagtaa ttgtttttta tctgaaatcc ttacttttgc aattcgtata taaccaccac
    15841 caccacgttt gctttctact agataaccac gttggatggt aaaacgggta ttaatcacat
    15901 agttgatttg tgaaggaaca cagttaaaga ggtctgccat ttcaatcctt cgaatctcga
    15961 tcatttcact attttccaga attttcttta tatatgattc aattaaatcc gaggtattct
    16021 gatgtgccat cttattcatt ccctttgact aatattgacc ttaattataa cgaatttgat
    16081 aatagaaaga aagaagaacg ctttttgtta aataaatcct ttagaatcaa caaaaaaaaa
    16141 tacggaatat actattccgt atc
//
LOCUS       DAYYEF010000058        15861 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000058 DAYYEF010000000
VERSION     DAYYEF010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.061"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(248..601)
                     /gene="tnpB"
                     /locus_tag="ACHA1B_002214"
     CDS             complement(248..601)
                     /gene="tnpB"
                     /locus_tag="ACHA1B_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="TnpB, as the term is used for proteins encoded by
                     IS66 family insertion elements, is considered an accessory
                     protein, since TnpC, encoded by a neighboring gene, is a
                     DDE family transposase; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HFM8702963.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(591..785)
                     /locus_tag="ACHA1B_002215"
     CDS             complement(591..785)
                     /locus_tag="ACHA1B_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702964.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
     gene            868..1476
                     /locus_tag="ACHA1B_002216"
                     /pseudo
     CDS             868..1476
                     /locus_tag="ACHA1B_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1496..2524
                     /locus_tag="ACHA1B_002217"
     CDS             1496..2524
                     /locus_tag="ACHA1B_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HFM8702965.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            2521..3279
                     /locus_tag="ACHA1B_002218"
     CDS             2521..3279
                     /locus_tag="ACHA1B_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HFM8702966.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(3365..4105)
                     /locus_tag="ACHA1B_002219"
     CDS             complement(3365..4105)
                     /locus_tag="ACHA1B_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LytR/AlgR family response regulator
                     transcription factor"
                     /protein_id="HFM8702967.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            4166..5419
                     /locus_tag="ACHA1B_002220"
     CDS             4166..5419
                     /locus_tag="ACHA1B_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HFM8702968.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            5714..5968
                     /locus_tag="ACHA1B_002221"
                     /pseudo
     CDS             5714..5968
                     /locus_tag="ACHA1B_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            6090..6416
                     /locus_tag="ACHA1B_002222"
     CDS             6090..6416
                     /locus_tag="ACHA1B_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HFM8702969.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            6484..7197
                     /locus_tag="ACHA1B_002223"
     CDS             6484..7197
                     /locus_tag="ACHA1B_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HFM8702970.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            7507..8359
                     /gene="licT"
                     /locus_tag="ACHA1B_002224"
                     /pseudo
     CDS             7507..8359
                     /gene="licT"
                     /locus_tag="ACHA1B_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator LicT"
     gene            8480..10345
                     /locus_tag="ACHA1B_002225"
     CDS             8480..10345
                     /locus_tag="ACHA1B_002225"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFM8702971.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            10359..11802
                     /locus_tag="ACHA1B_002226"
                     /pseudo
     CDS             10359..11802
                     /locus_tag="ACHA1B_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738852.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
     gene            11910..12611
                     /locus_tag="ACHA1B_002227"
     CDS             11910..12611
                     /locus_tag="ACHA1B_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM8702972.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            12737..13249
                     /locus_tag="ACHA1B_002228"
                     /pseudo
     CDS             12737..13249
                     /locus_tag="ACHA1B_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014566402.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(13647..13856)
                     /locus_tag="ACHA1B_002229"
     CDS             complement(13647..13856)
                     /locus_tag="ACHA1B_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="HFM8702973.1"
                     /translation="MYYFKQQILVSFINEKIILFSCYVSLINDVSLNKKADELNDQNL
                     IIFVHQLLLKIFLLTINSWICKNIT"
     gene            14097..14672
                     /locus_tag="ACHA1B_002230"
     CDS             14097..14672
                     /locus_tag="ACHA1B_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_process: GO:0009691 - cytokinin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HFM8702974.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            14672..15112
                     /locus_tag="ACHA1B_002231"
     CDS             14672..15112
                     /locus_tag="ACHA1B_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside 2-deoxyribosyltransferase"
                     /protein_id="HFM8702975.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            15128..15829
                     /locus_tag="ACHA1B_002232"
     CDS             15128..15829
                     /locus_tag="ACHA1B_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HFM8702976.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5315 a         2659 c         3315 g         4572 t
ORIGIN      
        1 cgtccaaata atttgttggt taaataattg accttttcat tcaatagttg gatttcagtt
       61 gtaagattct gaatggtttg ttgttgtgct tgattggttt tatgggcttc ttgaagcaac
      121 tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa ctgattttgt
      181 tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt tgtgttaacc
      241 ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga tcgatactta
      301 atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg tctttcgtcc
      361 gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa ccatcaccgt
      421 cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa acggcatctt
      481 cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca attccttttc
      541 gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa tcataaagca
      601 ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc gttatagatc
      661 aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc cgcgggttta
      721 cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatctc atttaattta
      781 tacatagaaa acctccagac ttcttgatag ctcaagtata tcttgaggtg catttgttag
      841 taaggtactg ttctatgggg cgcttaccca gaaaatcaac tttttgcagg agatgtatta
      901 gaaattgtat taaacgacca agcaggagaa gctgctgcta agggtgtgca gaacaagcca
      961 agtaccaacg atgaaattgg gaatcacaat ccaagtgata cgccagttgt ttatcatgat
     1021 gccccgcctt ttgcacctgc tacgaagatt gtagtagaag gtggtctctc atttcttgcc
     1081 ccttccaaac tcgattgtgg tcagatcaaa gcaactgggt tgacgcaaga agcatttggc
     1141 caaatggata tacaggaaaa attatggatt tatgatcagc gagaaacaaa aagtccatgg
     1201 atcttaacga taaaattatc tcagcctttc acaaccgatg caggattttc tatgcaggat
     1261 gtcctatatt tcaagaaagc tgaggagtat caattagtga atgaagaaga actggaaatt
     1321 gtcagaggac aaaattcaac gaatgtgcaa acagattatt cagaatattt aaataatggt
     1381 cgggcgttta aacttgtctt aaccaaagaa aatcagatag ctggtaatta ctcagcagag
     1441 atgacatgga cattagcaga tgcgccgaca gaataaagat caaggagaat gattgatgaa
     1501 tcgaatatgg aataaaagtc atcgaaacaa ctgctcttta cttctgatcc ttctccttgg
     1561 attcatcctt tggcagacac ctgtccatgc ctccgaattc aattttgcgg tagattttga
     1621 attaccggct aatcagattg ataagaacaa aacatatata aatgtaagga tggagcctgg
     1681 gaaaacacag gaaatcccct acacggtctt taaccgaaca gataaatcag taacagttga
     1741 gacattgatc cactccgcta cgacgaattc aaacggtgtg atcgaatatg gagaatcaaa
     1801 aagtaaattt gatgaaacat taagttatga tatgaaaaac ttagcaaaaa cagtgggaga
     1861 aataactgtc cctcctcaaa gtgcggtcac tgagacactt tcactgaaag ctccagaaaa
     1921 agagctggct ggtgtggtcg caggaggaat cacgtttcaa gaaaaaaaag agaacgtttc
     1981 taacaaaagt acagttggtg tcgtcaatca gttttctcaa gtgaaagcaa tcttgattcg
     2041 aaatagcgaa aaagagtctt ccccaaattt gaaattaaaa aaaacttatg cggatcaaag
     2101 cgatggaaga aatgtgatta aggcgaatct tcaaaatcca aatgcttctt atatgttcgg
     2161 cttgactaca tcggttgaaa tctacaaaaa agaaacaaaa gagccttatc tttcaataaa
     2221 aaaagaaaaa atagatgtag cacccaatac aaattttgat ttacttgtcc cattagaagg
     2281 aaaaaaatta gctccgggac attatcaagc ggttgtgaag ggtgcttgga aagaaaaacg
     2341 ctggaatctc cataccgatt ttgaaataac tgatgatgca gcggaccaat tgaatgaaaa
     2401 ggatattgat ttaaaaaatc agccagaaac atttgactgg cgatggctga tacttgttgg
     2461 agtcattctt attggcttat ttgctggatt atttatttta aaagaaagaa ggaaaaagaa
     2521 atgaaaaaaa caattgcatt aagtaccgtt ctagctggaa gtctattatt atgtacacaa
     2581 agtgtttttg ctgagaataa gagctcagcc actacagaag gaacgatttc tgtaacaaaa
     2641 ccagatgccg caaatcctga agacgttgtt ccagttcctc ctgttgatcc aaatgatccc
     2701 gatacgccgt ttacacctaa cgaaccaaat cagggaacat ccggattact gacgattgac
     2761 caagctccag atcttgattt tggaacaatc aagttaggta cagcaaaaac agtatatgct
     2821 gcattacaaa acggaacgga cagtacaggg acagcaacac aagtacagaa tttcgtacaa
     2881 gtaacggata aaagcggaat ttatgccggt tggaaactat cagtcaaacg aacagaattt
     2941 attggtacaa catctgatac gaataaacta actggttcaa aggtgaaatt caaaaacgcc
     3001 gtgattcgaa atagcgcaac taatagcagt ggaacgccat ctactatttc tggtactggc
     3061 gctgaaggaa ttgagatccc agcagatcag gcagtagatc tagtaactgc aggagcaaat
     3121 gaagggattg gcacatggat ttattcatta ggagagaatg tggaacaagg gagacaatca
     3181 gtggaattat ttgttcctgt atccaattat gccgtagaca actacgtttc aacattcaca
     3241 tggtcgttaa cagatgctcc tacagaaggg aaagcgtaaa atcaaatcaa tgacttcagg
     3301 gagtggagcc gattcaaggc caactccctg aaatctgcta tgcttacgtc tcagctctta
     3361 ttcatcaact cgaagcagtt ttttggaagt catggaaacg ttcctttgtc ttttcaaaga
     3421 tctttcgacc aacgagtaag gagtcaccat tgaaaaattc taacacataa tgagcagaat
     3481 caattttctg caattgcgat aagttgatac agtaagattt taatagtaaa aagtaagcat
     3541 acttttccaa ctctgtcttc aattgtttta aagaagtatt cactaattta tcttctgtag
     3601 ttgttttgac cataacttgg tttttcaaac ctttgatact ttcaatatat aaaatttccc
     3661 gaggatacag gacgagactt ccaccttttt gatcaataaa gattttatcg acatttacga
     3721 tttgctgttc tttccaattg atctgttcta gcacttgacg aatttgttca gataaattcc
     3781 tgtcttttct gatatatcca atcggaagga ttttccgatt gatgatctct actgcaaaat
     3841 tcgtataagc ggtgaaaaaa acaatattac tatgtgcatt ttttttacgt atttgttcgg
     3901 cgacatcaat acctgtgagt gattgcttca agtcgatatc gataaagaaa acatcgtgat
     3961 tatcaatagt acccaactgg atcaactgat tgatttgaga gatagaagtg agctgcacga
     4021 tattctcgat atgatgattg accaattctt tgatgatcca ttcgctgtga aactggttat
     4081 cttctatgat aaaatacttt ttcatatgca ggctcctatt aaaaaaatat gtgtacattt
     4141 tgaaacaaaa caatggagga ataagatggt cgcaacagtg acactttatt tgacctttac
     4201 tttgatttta gatttaggta tctatttatt cttttcgaaa caactgctag taaaaaacag
     4261 ctttggtttt atagctttga tggtggtgac acttttattt cctatcccta aagtgagctt
     4321 tccttaccta gttggcttat tattgatgtt tcttttttat tttactacga aaaacctgtt
     4381 tatcagctgt ttgatcagta atcttttttt tgctatcact ggactcagct tttttctggt
     4441 ttttgatctg atggattatt taggaaagag acatcttgga acagcaagtt tttttgcact
     4501 acttatcgca tttattttct atctattagt aaaaagtata gacaaacaga cgagatttct
     4561 caacttgctt tttacttatc caactgaaca ctattttgga ggtatttgta ttttattaag
     4621 ctggggcgtg atttacttgg tattgggaag tgttcacttc cgctcatcta attatctgct
     4681 tctatctctt ttgtcgatag tcatcagttt tttttctttg tttttttcca ttatgttgat
     4741 cagtttccaa gtaaaagaaa gacaacatca ggaatcgctt caactgtatc aaataaatga
     4801 agaatattac catcatctag aggaattcaa acatgattat aaaagtctac tgttttcatt
     4861 aaaaattact cttcaggaaa ataaaaaaga aacgttggaa tttttagaaa tcttagaaga
     4921 tcattctgca gctatttttg aaaaaccgca aatacaacag ctaacaaata ttgtatcccc
     4981 agctgtcagg ggtgtctttt taaaatttct agaaaaagca gaatcggaga aaatcccgat
     5041 ccaagtagtt attcctgtcg aagtgaaaac aatcccgatt gatctggttg tttttattcg
     5101 ctgtttatct atttttattt ctaacgcatt cgatcatcgt gtagccgatc agagtccgat
     5161 tacgatcaat ctgctggaag aaaaagaggg attacgtttt agtatagcga acaaggcaaa
     5221 tccgacgaat ttgacgctat cggagatggt caaaagagga aaaacctcta aaaaaaatgg
     5281 cgggttaggt ctatacagtg cgaaaaaaat gttggatgtt tacgaaaatg cagaactaaa
     5341 aatcgaattt tcaaaacaga atcactattt ttttgtagaa atgtatctgg catctagaaa
     5401 gagcaaatca gcctactgac ttactgtcaa aggataagct tgaggaaagt ctacacggag
     5461 atagagacaa caacacagca tattcaaaag aaacagaagc gtgatgaccg ttgtcaccct
     5521 tctgtttctt ttgctatgta gttaaacaaa gtagttgaca cttccgctac ttagtattag
     5581 tacgaaagta tacttcatga tactaagtag ataagaagtg aaaagcggaa cccacgatcg
     5641 tcaaaatgct aactgctttg cttacaccag ataaagggaa gagcaatatc gcttatttta
     5701 ggcgtggaga agcaagaaaa tccctacgat cacacaaaaa atgctgaccc agcagttaag
     5761 agagttagaa caagatggca ttgtccatcg aaaagtctat aaccaagtcc cgcctaaagt
     5821 agagtactcg ctcaccgaag aaggaaaatc attaagagag attctagtag cgatgtctgt
     5881 ttggggagaa gaacgtatcg aaaaacaaaa agcctcaggg gaagaagtca cattactgca
     5941 tacacatggt ggctacctaa attactgatt tctatgacat ttattttaaa taaaagaaaa
     6001 caggagtttt tttaaaagca tcatctattt tttatgtaaa aaaatggtat gattaatcaa
     6061 gtaagaaatg attggaagaa ggcaagcaaa tgaatagcat ggaaaaagtt aaccagttta
     6121 gagatgaacg taattggcga caatttcata acgaaaaaga tttggctatt tctatttctt
     6181 tggaagcatc tgaattgtta gaactttttc aatggaaaac gccggaagaa gtaaaagaaa
     6241 cacaattaga acgaatcaaa gaagaactgg cggatgtatt gatctattca tacatgatgg
     6301 cagacaacct tcagctggat ctagatgaga tcattgaaga aaaattgatc aaaaataatt
     6361 tgaaatatcc tgtagaaaaa agcgcaggtg tacgaaaaaa atacacagag ttttagaaat
     6421 gtgtcattcg gctgttggaa agagcaaaag aaaaacagta aaatgagtct ggagggagag
     6481 aaaatgaaaa aaaaaggaaa agcaaaaaga tggctagtca atatcctctt gttcctcttg
     6541 ttattagtag gactagcttt gattttcaat gaacagatca aggattatct tgtcagagag
     6601 acaggagata aatatgctat agcgaatgta acaaaagaag atctgaaaaa gaataacgat
     6661 aaagatgtca gttttgactt tgatgcggta gaaccaatga cgacagaagg ggtcatgagg
     6721 tcgcagatga gaggaacaga tctaccagtg attgctagta tcgcagtccc ttcagtttca
     6781 atcaatttac cgattttcaa aggcttggat aatacgtcac tactttacgg agcaggaaca
     6841 ttatctccag atcaagaaat gggaaaagga aattatgcct tagcaagcca tcgtgcaacg
     6901 aaccctgaat tgttgtttac accgctggaa aatttagaga tgggtgccaa gatctatttg
     6961 acagatttag aaaatgtgta tacatacaaa acatttttta aagaaaaagt tgctcctaca
     7021 gatacccaat tactgaatga agtcgaggaa aaagaaattg tcacactaat tacttgtggc
     7081 gacatggacg ccgtcacgcg actagttgta caaggagaac tggaaagtgt tacaccgata
     7141 aaagatgcga cagatgatat gagatctgct ttcaatctag agacaaaaac attttaggat
     7201 actgggacat aagtcgttac agattaaaaa cagccaaagg atatgaatcg ataaggaaaa
     7261 accaatttgc tgaaaaaaag aggaacgcaa agaggtgcat ctctgatttg gttgttttct
     7321 agatagactt gtgttccagt ttttttattt tttatatgaa aaggcttgca taaataaaaa
     7381 ttcgatggta tgatgatttt gaataagaaa tggattgtta ctgtacggca ggcaaaacca
     7441 gaattcagct aagaaacagt aggcgaattc taggtttttt tatttttctt gagagggcga
     7501 agcaaaatga aaattgataa aattttgaat aacaatgtcg tcatttcgaa aaatggattc
     7561 ggggaagaag tcgtttgtat gggaaaagga ctagcttttc aaaaaaaaga ttggggacga
     7621 gatttcgcca gaagcggtcc aaaaagaatt tattttaaga gattcttttg ctaaaaacca
     7681 attccagcag ctgatggctg atattccggc agaggagatc gaatgggtca aacaagtagt
     7741 cgaactggct gaagataaac taaaagttga attttcgcct aatatttatc tgacattgac
     7801 cgatcatctt cattatgcga tcacacgagc aaaagaaaat atccaactgc ctaatccatt
     7861 attatttgaa acaaaaaaat tttatccgaa agaatatcaa gcagcgaaag aggctctttt
     7921 gttcgtgaaa caaaagacgg gtgtggaact ttctgaggat gaagccggtt ttattgcctt
     7981 tcattttgtg aatagccaac aaggaaacga agacatgcaa gtgacgatga ccgctaccac
     8041 aatggtaaga gatatactga gtatcatcag taaattcttc ggcatcgtgt tcgatgaaga
     8101 atctttgaat tatcagcgta tcattactca tctgcagttt tttgcccagc gttatctcaa
     8161 aggggaagga tctgacgagc aagatgaatt tctctacgca ttagttcaag gaaagtatcc
     8221 aaaagcgttt cattgtgtcg aacggatcaa tgagtatctt cgacaaacgc aaaaacagga
     8281 aatggggatc gcagagcaga tttatttaac gattcatatt caaagagtag taagtgagaa
     8341 aaaaagcatc caatcataag gattgttact gtatggcagg caaaacctgg attgaaaaaa
     8401 taggttcacg aatgtttgtg actgtttttt tcaatctggg tttttatttt ttaaataaaa
     8461 aagaaagaag gaaaaaacaa tggataatca agcagttggt cgtcgtgtat gggaagcggt
     8521 aggaggacaa aagaatgtca aaagtttagt acattgtgct acgcggttgc gattcagatt
     8581 aaaagatgaa tctttagcag atacgcaaaa gttaaaagaa gacccggacg tgatccaagt
     8641 cgtacaaagt ggcggtcagt atcaagtagt gattggcagt aatgtagcag atgtttatca
     8701 atcgatcgtg gatgaggaag gtcttgcagt ttcggaggat ggaaaagaag agtccaaaaa
     8761 tattttgaat cgtctgatcg atattatctc tagtatattt acaccttttc taggggcgat
     8821 ggcagccgcc ggggtattga aaggattctt atcattggca acggtgatgg gctggctgac
     8881 agctgatagc ggtacttatc aaatattgtt tgctgcagca gatggtgtct ttaccttctt
     8941 acctgtcatg cttgctttta cagcagctaa aaagttcaaa gccaaccagt ttttagcagt
     9001 agcaattgct atggcacttg tgtatccagc tatcacagca gttgctggtg cgggagaagc
     9061 tatcagtttc tttgggatcc cagtgattct ttcaccatct ggttatactt cttctgtcat
     9121 accaatcatt ctagccgtat gggttcaaag taaattagag ccattcgtaa aaaaagtgat
     9181 tccgcaattt ctgcaaatga ttttagttcc gcttgtcgtt ttagtagtga tggttccatt
     9241 aacatttctt gctttaggac caatcgggac ggttgccggt aatgctttag gcggtctctt
     9301 caactcgatt tatggattta gtccaatcgt agcaggtcta atcatgggaa gtttatggca
     9361 agtattcgtg atgttcggca tgcattgggg attcgtaccg atcatgtttt tgaatatcga
     9421 acaatatggg tttgatgtat tgatgccaat gcttcttcca gccatcttgg cacaaggtgg
     9481 ggctgcttta gctgtagcat tgcgaacaaa agatacgaaa cttcgagcat tagggatttc
     9541 ttctacagtg acttcgttat ttggaatcac tgaaccaact gtgtatggtg tgacattacc
     9601 tttgaagaaa ccattcattg ccgcttgtat ttctggaggt attggtggag ctattatcgg
     9661 attttccgga gtaaaagctt tctccagcag tttggtcagc ttattgacga ttccgacttt
     9721 cattaatacg gtggatggtg tagagtcaaa tgtgacagta gcagtaatag ctacaggaat
     9781 tgcttttgtt cttgcattcg taggtacatt gattttagga tttgacgaac aaacacaaga
     9841 caatcaatta gaaaacaaac atgcgaatgc aggagaaccg attacttcag cacggcatac
     9901 cttaaaaagt cctttaacgg gtaaagtact gccattgagt gaagtaccag accaagtttt
     9961 ttcttctggc gtgatgggaa aaggtatcgc tattgatcca gaagtaggag aactagttgc
    10021 acctgcagac ggagagatca cgactatttt tccaactgga catgctgtag ggatcacaac
    10081 gactgacgga gcggagattt tgattcatat cgggatggat acagtagaat taaatgggaa
    10141 tggctttgag atcttagtca aacaagggga tctcgtcaaa gcaggagatt tattgattcg
    10201 ttttgacatc gaagcaatta gagcagctgg ctatagcgta atcactccag ttgtcattac
    10261 gaatactgat gcatttgccg atatacttga attagaccaa aaagagatta ttgcaaacga
    10321 agatgttctg gcaattgtaa aataaggagg aaatcaggat gcaatcacgt ttttcagaaa
    10381 aatttttatg gggtggagca actgctgcca aatcaattag aaggggctta tgatcgagac
    10441 ggaaaaggac tatccgttgc agatgctatg cctggaggta agcagcgctt tgcgattatc
    10501 ggcagtgaag aatttgactg gacgattgat caagaaaaat atatttaccc gaatcatcga
    10561 ggaatcgatc attacgatcg tttcaaagaa gatcttgcct tgtttgcgga aatgggattc
    10621 aaatgttatc gtttttcgat tgcctggaca cgaatttttc caaatggaga cgaaggtact
    10681 cctaacgaag cgggattaga attttatgat cagctgattg atgagtgctt aaaatatgat
    10741 attgaacctg tgatcacgat ttctcattac gaaatgcctc ttcatttggc aaaagaatac
    10801 ggtggctgga aaaatcgaaa actgatcgac ttctatgaac gatttgctca gacagtatta
    10861 gagagataca gcagtaaagt caaatattgg atgactttca atgaaatcaa ttcggccttt
    10921 cactttccag ctttaagtca aggattagta aaaagcaatg gagcaggaga gtaccaaaat
    10981 attttccaag catggcataa tcaattcgtt gcaagtagca aagccgtaaa aatcggccac
    11041 gaattgcgtt cggatatcca aatcggctgc atgattatct atgcaacaac ttacagcatc
    11101 gatgccaatc cagtcaatca ggcagcaaca atgatccaaa accaagaatt caattttttc
    11161 tgcacggatg tccaagtacg tggagaatac cctgcataca cagcgcgtac ccataaaaaa
    11221 tatggagtcg atccggaaaa attagagcaa acggaaaaag acttccagtt gctaaaagaa
    11281 tatccagtgg actacatcgg atttagttat tatatgtcta cggcaatcaa tgagactgat
    11341 ccacaagcag caacttcaga agggaacttg ctgggaggag taaaaaatcc gtttcttgag
    11401 gcaagtgaat ggggctggca gatcgatcca gaagggctga gaatcgcatt gaatgaatta
    11461 tacaatcgtt accagaaacc attattcatt gttgaaaacg gtcttggagc cattgatcat
    11521 atggaagagg atggcacgat tattgatgat tatcggatcg attatttacg tcgtcatatc
    11581 gaagcgatgg ctaatgcagt agcagacggt gtagatttga tgggctatac gccttgggga
    11641 tgtatcgatc ttgtcagtgc atcaacagga gaaatgagta aacgttacgg ctttatctat
    11701 gtggatctag acgatgaagg aaatgggaca ctgaatcgat caaagaaaaa atcttttgat
    11761 tggtataaag aagtaattgc ctcaaatggc gtaaacttgt aattaaagca gctgaatgaa
    11821 aaagaacaca cttctcacat gtgatttgtg ttcttttttt attttttatg tgctattctt
    11881 ttagtaatag taaagcaaag ggtgacgtta tgaaaaggac acgtgtacta tacttggaag
    11941 tcgcagataa aattaaagaa gatattttct caggaaaata tccagtcggt tcgatgttgc
    12001 cgacagaaag tgaattagaa gaactgtttc aagtcagcaa aatcactgtc cgaaaggcaa
    12061 tcgaactgct ggcatcagat gaatatgtcg caaagaaaag tggtcgtggg acgacggttc
    12121 taagcaatcg tccttacaat cgattatcca aagcggcaag ctttacgcaa atcttggaga
    12181 actcccgata tgaagtccgg aaagaaacgc tggatttgca attggtccat ataaagaagg
    12241 aagatccttt gttttccttt ttcggtgagc aagctgtttg ttttaagcgc ttatattatt
    12301 tgaacaatca gccttatatt tattttgttc attatcttcc acaagaaatg atgcaattca
    12361 gcagagaaga atttggcaaa gaatctttgt atcgtttgct gacgaaaaaa ggatatacta
    12421 ttgactcatt ttctgatgat ttctcggcag tatttttaac agaagaagaa caaggaattc
    12481 tgaaaacaga cgcacagatc ggcatcaaac ggatacggaa atcgtctacg caaattgggg
    12541 aaatgattga atattcggag gcggtctacc atacggagct gcatccttac catattgatt
    12601 atgaaacata aataaaaaaa gaggttgtga aaaagctgcc ctgcatcaag taataagaac
    12661 agccaaacaa aaatagcttc tcatattttt cgtttggtta ggcttattac cgcagataca
    12721 cggctgtttc tggattacca tttattctgg ataagggggt gtggcacgat tttcagaagg
    12781 aatctatgaa ccaatcactg tattgatttt agcttcgatg gtaaccccat tcggcttgac
    12841 gatcgcttat ttcttaggga aaatcattcg taaaaatata ctcaatcgtc aagaaatcga
    12901 tacattgaag accgcttttc ctatggggat ctgtcagatc acagagggat gtttccctat
    12961 cgtattgaac gacttggcac gcaatgtcat agcaacggga gtcggtggga cagtaggtgg
    13021 cggattaagc atgttttggg gcgcagatag ccgtattccg gcatcgggaa tgtttgcagt
    13081 cgctacgatg accagaccat gggcattcat tggtgcattg ttagctggtt cttttgtcac
    13141 aggaataacc attttattat tgaaaaaacc agtagatccg aatgcagaaa tcatccaaga
    13201 agaaaaagag gaagaagaca tatcttggga tgatttgaca attagttagg agaggcagaa
    13261 tggattacaa gaaaaaagta caatagatgt accttgagac aggaatggta tgaaagaatc
    13321 agagttagaa agaatcgaat atacagattt tggtttagga gcgatcgaaa ctgtccagag
    13381 catcggcacc ctccttgaaa tgacgatgaa ggaaaaatga gaacctttcg ttgtcgaaag
    13441 ggtctggtat accttatgtc gaaggaaagg aaacaaaaaa actttcctgt actattccaa
    13501 aaaggaaaga aagttattat acagtaaaaa aagaaattat tcttcatgct agagatcagt
    13561 acacgttcga gcccaatatc aaacactagt tccaggcagg cgcaacaggt gcggttatca
    13621 ctgaattttc ttccagcagt gacgattcaa gtgatatttt tacaaatcca gctatttatc
    13681 gttaacaaaa agatttttag gagaagctga tgaacaaaaa tgatcaaatt ttgatcgttt
    13741 agttcgtcgg cttttttatt tagagaaaca tcatttatca gtgaaacata acacgagaac
    13801 aaaatgattt tttcgttaat aaaagaaaca agtatttgtt gtttaaaata atacacgtta
    13861 ttggcatata ggacgaaatc ccagtatctt ctataagtaa gtcatttcat atcgatgaaa
    13921 acacgttatt tatttttgtt ttatctataa aatggctgaa aaatgatttt tttctaaata
    13981 ctatatatag tggcgtctat cctatatacc actaaaaaac tacaaaatct agtcttttat
    14041 tttaaaaaaa cacgtgtaga atgaagatag acttttgagt tagggagtgt ttttttatga
    14101 aacttactgt tttttgcggt tcccgttttg gtaataaaga aagttacaaa tttattgcgc
    14161 aaacgttagg aaaatacatg gcacaagaag aaatcgaact ggtttacggt ggttcatact
    14221 ccgggattat gggagtgatt agtaaaacag tactggaaaa taacggaaaa gtcacaggta
    14281 tctatccgaa tgggcttttt gaaactgaat tgcctggaaa agatgttact acatttattc
    14341 ctacagaaac gatcgatgaa agaaaggtat tattatttga aaagggagat gctgtcctcg
    14401 ttttccctgg aggtctaggt acattggagg aattctcaca acttctttct tggatagcaa
    14461 tcggtctgac gcccgacaag ccaatcggaa tattgaatat tggcggttat tacagcggct
    14521 tgcaacaatt attagaaact tttgcaaaag aggattttat ggataaaaaa tggttggatc
    14581 aagtaatctt ttccaacaat ccattggaac tggtcaatga attacgagca gtatctatta
    14641 aaaatcagtt attattgaag gaggcaaaat aatgagtcaa atatatttag caggaccatt
    14701 tttttcagag gagcaaatcg atcgagtaag tcgtatcgaa aaagcgttgg aggaaaacaa
    14761 aacagtcaca agtttctact ctccacgtca tcaccaagaa agcaattatg aactattcag
    14821 cgctggatgg gcgcaggaag tatacgaaaa agatatggaa gaactgacaa atgcagaatt
    14881 tgttgttgct atccttgact ttgagcatca aacaatcgat ccaggaacgg cttacgaatt
    14941 aggtgtggca actatgttga aaaaaccgat gatcattgta caagaagaga cggtacctac
    15001 gaacttgatg attacacaaa gtctccatac gtatttaaaa tcagaccaag ctgtacgtga
    15061 atatgatttt gaaacattgc ctgttgaaac ttacgtaggc gagtacttat agaagaggaa
    15121 gggttgtatg tcagtgattt tgatttcagg aacgattggt gcaggtaaga gcagtttgac
    15181 ggatatgctt gcaaaagaga ttgattctaa accattttat gaaaatgtcg aagataacga
    15241 agtattgccg ctcttttatt caaatcctga gcagtacgct tttttattgc aaatcttctt
    15301 tttgaacaag cgatttttag caatgaaaaa tgctttagtg aacgatgaca atgtgctaga
    15361 ccgatccatc tatgaagata gcctgttgtt ccatctaaac gctgatttag gtcgggtaac
    15421 ggatatcgaa gtacagcagt acgatagctt attagatacg atgctaaacg agttagatga
    15481 tgttgctcca aaaaaacggc ctgatttgat ggtccatatc aaagtttctt tggacacgat
    15541 gctagaacgt atcaaaaaac gtgggcgtga ctatgaacag ctagaaagcg atgagacgtt
    15601 atatacctat tatgaaacgt tgaacacccg ctataatcaa tggtatgaag attttgatgt
    15661 atgtcctaaa atacaagtgg atggggataa attcgatttt gtagaaaatc cagaagatgc
    15721 aaaaaaggtg atccgtcaga tccaagaaaa attagctgaa ttggaaggaa agcctgctgg
    15781 aaaatatttt acggataacc agcatgcaaa aggtcaagaa ttaggctaaa aataaaaaac
    15841 caaacgacgg gaaagaaaaa t
//
LOCUS       DAYYEF010000059        15544 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000059 DAYYEF010000000
VERSION     DAYYEF010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.062"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            120..1754
                     /locus_tag="ACHA1B_002233"
     CDS             120..1754
                     /locus_tag="ACHA1B_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFM8702977.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(2021..3190)
                     /locus_tag="ACHA1B_002234"
     CDS             complement(2021..3190)
                     /locus_tag="ACHA1B_002234"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="HFM8702978.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            3394..4569
                     /gene="mltG"
                     /locus_tag="ACHA1B_002235"
     CDS             3394..4569
                     /gene="mltG"
                     /locus_tag="ACHA1B_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008932 - lytic endotransglycosylase
                     activity [Evidence IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HFM8702979.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            4705..5184
                     /gene="greA"
                     /locus_tag="ACHA1B_002236"
     CDS             4705..5184
                     /gene="greA"
                     /locus_tag="ACHA1B_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HFM8702980.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            5353..6084
                     /gene="liaF"
                     /locus_tag="ACHA1B_002237"
     CDS             5353..6084
                     /gene="liaF"
                     /locus_tag="ACHA1B_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein
                     LiaF"
                     /protein_id="HFM8702981.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            6081..7148
                     /gene="liaS"
                     /locus_tag="ACHA1B_002238"
     CDS             6081..7148
                     /gene="liaS"
                     /locus_tag="ACHA1B_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     LiaS"
                     /protein_id="HFM8702982.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            7155..7787
                     /locus_tag="ACHA1B_002239"
     CDS             7155..7787
                     /locus_tag="ACHA1B_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HFM8702983.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            7927..8592
                     /locus_tag="ACHA1B_002240"
     CDS             7927..8592
                     /locus_tag="ACHA1B_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HFM8702984.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            8620..8913
                     /locus_tag="ACHA1B_002241"
     CDS             8620..8913
                     /locus_tag="ACHA1B_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HFM8702985.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(8981..9928)
                     /locus_tag="ACHA1B_002242"
     CDS             complement(8981..9928)
                     /locus_tag="ACHA1B_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HFM8702986.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(10106..10909)
                     /locus_tag="ACHA1B_002243"
     CDS             complement(10106..10909)
                     /locus_tag="ACHA1B_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HFM8702987.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            11055..11969
                     /locus_tag="ACHA1B_002244"
     CDS             11055..11969
                     /locus_tag="ACHA1B_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFM8702988.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            12017..12487
                     /locus_tag="ACHA1B_002245"
     CDS             12017..12487
                     /locus_tag="ACHA1B_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_process: GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HFM8702989.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            12572..13180
                     /locus_tag="ACHA1B_002246"
     CDS             12572..13180
                     /locus_tag="ACHA1B_002246"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004784 - superoxide dismutase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HFM8702990.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            13314..13514
                     /locus_tag="ACHA1B_002247"
     CDS             13314..13514
                     /locus_tag="ACHA1B_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFM8702991.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            14268..15494
                     /locus_tag="ACHA1B_002248"
     CDS             14268..15494
                     /locus_tag="ACHA1B_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFM8702992.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         5304 a         2330 c         3017 g         4893 t
ORIGIN      
        1 aaacactact tttgtaatat aaaaaatatt ttattaataa taaaattaat cacattttat
       61 atagtgacta atctagtgtt taaaaaaaat aaatgatact atatgtaata taaaaaaaca
      121 tgaggtggta tatgaatttg aaaaaaattt tttctgtaaa aatatttata gtttatgcat
      181 ttgttagttt attatattta tttccagcat ttaaaaacat ggaaatattt ggcttttatg
      241 atacggcatt tcacattaat cgtgcgttaa gtttagaatc tatttttagc tcccctatta
      301 attttgaaac gtttagatca tatggcatgc aagtaaataa tttttaccca tggttaactc
      361 tatatccttt atttttattg atcaagttta ctaatttagc aataggctat aacctttttc
      421 tttatattgt tacgctcatt actctattta tatgtcatta tgtaatgtat gaaattacca
      481 aaaaacatgt tactagctcc tttttcgcta ttatatatac aacatcttct tttaggagtg
      541 tagaaatatt tcttcgaggg gcaatggggg aattactcgc aatgtcaata cttcctctta
      601 ttttactcgg gtttataaag ctttacgact caaaaaaaga atcttgggtt atgttggcga
      661 ttagcatgac tttattaatt tacactcatg ttctttctgt agctatgact atggtaatga
      721 ttataattgc tttaattatt caattttatc ggaaaaagaa aatagaaatc ttcttaatta
      781 ttaaattaat aaaagctgct atagttactt tacttctttc actagcgttt ataggtccta
      841 tgattgagca gacattgtat caagatctga atagacctta tgtggatata ttacaaaaaa
      901 gagcaattta tctgggtaaa gagtttttga ttggaagtat agattcagaa ttactatcat
      961 ttggtattgg cttaactttg cttatttgtt taattatact aacatttaac tttaaaaaat
     1021 taggaatctt atctaaaatc acttatataa tgggtataat atctattcta ctttgtacaa
     1081 aaatatttcc atggtttgcc ttacaaaata ctcctttaaa tattattcaa gctccttggc
     1141 gttttatgat attttcaaca ttgttcatat ctttttcagt atctctattt atttctccac
     1201 agttggaaaa attttcttat acaaggagaa gaaattttat actattatta atattagcta
     1261 tttcaatttt aaattattca tcagtagtta acatggtgaa agaaatgaat tttcaaggaa
     1321 cttattctaa tgaacaaatg gaaaataaac ttgaagaatt tgagaatttt gattatgtac
     1381 ctataggcta taaaaaagat caattgcttt tgaaaaacca tcaagttaca gaagatggtc
     1441 aagttattta tagtagcttt tctccaaata aagatgaaat tacatttacg tttaaatctt
     1501 caaaaggcaa aacaatagtt ttacctgtat tccggtataa aggattaacg gttactgtta
     1561 attcaaaaaa tgctacagta ctaaaacaag gaggtccttt tgttacagta aaaagtgaaa
     1621 gtggaataaa taaagtaaca atcaggtatt catacacatt tttttctaaa atctcattat
     1681 ttatttctat aatcacgcta attgttcttc ttttttattg cataaaatta aaaataagaa
     1741 caagccatga atgatttgct agcacatatt ttagcaatct aaagatacta ttttagattt
     1801 aataggccct ttgtcaaata atgttggtaa agagaaatct tagaataatt tggacagaac
     1861 agaaagaaga acacctcttt ctgttctgtt tatttggaat taaagtctgt agcaaaaatt
     1921 gatttttaga tttgtcccac actctttcct acgtttagtc gagtactttt tttaagcaaa
     1981 tgctattcaa agaagtagta tttgctatct tttcatcata tcagctattt gccaacttag
     2041 tagttccttc catcaggtca tagatttggt ttcttagatc agcagtaggc agtttgatag
     2101 ttttgtcagc ttttatattg ctttccatga tgatagcatc ctgtgaatct ttgctaaata
     2161 tagcagatgt atcaaaagag tcgatatttc cttgcgacag gatataatta tctccgctat
     2221 ataccccacc actatatgga tgtccattcg cattttcacg ccataatgag aagagtaagt
     2281 ctttggaaac tagttttcca gataaaactt gtgtaaacag cgtatttaaa tcatagacgg
     2341 acatactgat attaccagtc cctaattcgt tatggatctc tgtttcagat tctgtcagtg
     2401 gtttaaagta atcatcctct ttagacattt gataggatag tgcatgattg gatgaatttt
     2461 tgacttggtc ataaaatttt gtatgctgta atcctaaagg ttcgatgata tcatcggtca
     2521 ataatttttc atacggttga tttgttaatt tgatcaaaat tccagtcaat atggtaaagt
     2581 tcaatgaatc ataatgagag gtctgataat ctgtaaattt taagtgctga atcgcaaatt
     2641 gaacgacttc ttcatcagtc atcggtatgg ttggagaagc agttcggtgc aagcctgagc
     2701 gcatatacag caagtcacgg atagtaattt gctggctgcc agcaatttgt ggatagaatt
     2761 gagccagctt agtatctaaa gaaaggtgcc cacgctcgac ttgttttaaa atcaaaagag
     2821 tagtcaatgc tttttgaacc gaaccaatct gataataaag agaaggatca tttggttgtt
     2881 gcgtgagttt attcgcatag ccatagcctt tttccatgat gatgcgatta tttttcttta
     2941 cgtaaattga gccaatataa tcattttttc ttaatagttg atcgattttt tcaacgagct
     3001 gttgttcatt ggtagtcagt atcaactttt tttgagctga ttgagcatgg gcaactatct
     3061 gagagtgttc attattgtaa aattgccatc caagaatagt tcctgtagag aacgcactaa
     3121 ggctaaacaa cacgacaacg atcattaaaa atgaatattt tcttttttta gcatgttttc
     3181 cttttttcat aatagtttat ttagtctcct ttctttttta cagaaagaat aaagctaaaa
     3241 tagcttgtat cttgataaca tttattttaa tcttatagta atggatttac tacttacatt
     3301 tttgatagaa tatttaaata aaatcattca cgccaattca aatatcatgt ataatgaata
     3361 aagttacgaa cttgatagta aggaggagtt gttttgtcag gaaacaaaca acacccaagt
     3421 aaagataaaa aagaagccag taaggcagct acagcagata taatcgacaa gcggagaaat
     3481 ctgcgtaaaa aagaagataa gattgtgagg aagatcattt tagtgattgc tcttacatta
     3541 ttgattattg gcggatttct tggatttacc gtgtatcgtt atgtagatag cgggttgaag
     3601 cctttagata aatcagatga ccaattagtc caagtcgaga tcccgagtgg ctcttctaac
     3661 aagcagattg gtgagatttt ggagaaggac aatattatta aaagcgggat tgttttcaat
     3721 tattatacaa aatttaaaaa tttaactggc tttcaagctg gctattatca gttagcgcct
     3781 aatatgactc ttgacgagat tggcaaacag ttgcaagaag gcggtacttc tgagccaaca
     3841 aaagttgcag atgggaaaat tgccattcca gaagggtacg atatcgatca gattgctgaa
     3901 cgggtagcga aggtaactgg taaagacaag aaagaatttt tagatttagt gaatgatgag
     3961 actttcttta acgagttgca ccaaaaattc ccagaactgt tggaaagtgc atctaaagct
     4021 gagaacacaa aataccgttt ggaaggttac ttattcccag ccacatatga ttattacacg
     4081 agtacttcgc ttaaggatct agtgattgaa atggtgaaca agacgaatac ggtcatgcaa
     4141 aactattatt cagctatcaa gcagaaaaat ttgactgtac aagaagtttt aactctagct
     4201 tctctagttg aaaaagaagg cgtaaaagaa aatgatcgta aaaacattgc acaagtcttc
     4261 tttaaccgaa tcaaagcaaa tatgccactt cagtcagata tctctgtttt atacgcatta
     4321 ggtgaacaca aagaattagt gacgtatgaa gatacagctg tagattcacc atataatttg
     4381 tataccaata ccggctatgg acctggacct tttgacaatc caagcgaaga ggcaatcaag
     4441 gcagtattag aaccagcaga aaatgactat tattatttcg tagcagatac gagcactgga
     4501 aatgtttatt tcgctaaaac ttatgaagaa catatggaat tagtggaaaa atatgtaaat
     4561 aattcttaga aaaacaggct ctagacattg atcattttta gaaaaacatt tacatttgaa
     4621 gaaaagcgtg gtaatctttt ttggactata ttcctcaaaa gattaccttt tgcggtattt
     4681 tatcgaaaaa aggagacgtt acacatggta gagaaagttt atccaatgac tctagaaggt
     4741 aaagaaaaat tagaaaaaga attagaagaa ctaaaaacag tcaaacgcgg agaaatcatt
     4801 gaacgaatca aaattgcccg cggtttcgga gatctttccg aaaactctga atatgaatca
     4861 gcgaaagatg aacaagcatt tgttgaagga agaatcacaa caattgaaaa tatgattcgt
     4921 tttgctcaaa tcatcgataa cgacggtgta gatgcagatg aggtatcaat tggtaaaaca
     4981 gttacattca tcgaactacc agatggagaa gaagaagagt acacgattgt cggaagcgct
     5041 gaagcagatc cgttttctgg caaaatttcc aatgattctc ctattgcgca agcattgatt
     5101 ggcaaacgta aaaatgatga agtaactatt gctactccag gtggcgatat gttagttaaa
     5161 atcgtcaaag tagaacaagc gtagtctgac tgaaagatct agagagttca tcttactgat
     5221 gatacactct agatcttttt ctctttgtgt attttagatt tcaacaaacg atcttacatc
     5281 taaagtccta tagccaacag ttaaaaaaat aggtatgatg aaatgagaat gtgtcaggag
     5341 ggagaaagag cgatgaatag ttcttggcgt ttttttgtgg tagttgaagc actactgctg
     5401 ttatttgctg tttggcaaat cgtaaacaat actggacttt tgcttttagt gatattcggt
     5461 attttcaata tatatctagc tatgcgcaaa catcctcgta ctaaatttca aaattttcaa
     5521 ttgatattag gaagtttggt catttttttt agcttagtca acagtcctgc tttatggatg
     5581 atggctgtat ttgccgtttt atttattggt ctgaaaggtg tagagatttc agggatagat
     5641 ttaaccaaaa atgctttttg gcgaaagaaa cagatcatga tgatccaaac agagcaatta
     5701 aaaacacata ataatgagcg gaaaagacag caattattcg gtaaccaacg tattggaaac
     5761 gacgtctatg aatgggacga tatcaacatc gccgtcattt ctggtgatac tatcatagat
     5821 ttgggcaata cgcttttgcc aaaagatgat aatattgtga ttgtaagaaa agggataggc
     5881 agaacacgga tcttagtacc tttgggcgta gccatccgat tagagcatgc gacattagta
     5941 ggaaatgtct tgtttgaaga agagcaattt tctttgaaaa atgaacaaat caaaatctac
     6001 agcagtgatt atgatgaaaa ccctcgtaga ttgaagatta ttactaatac cttgattgga
     6061 gatgtcgagg tgatacgaat atgatgggaa aaatatccag agcgatgcta gctgtttatt
     6121 cggggattgc ggctttcctt attattctat tttcactttt cacttatttt tatgccagca
     6181 atcaaagtca ttggtgggga gaattactgc gtgcacgttt attatatgtt ccgcttatct
     6241 tccatttgtt agccatttcc ttaggtgtag gattaattgt ctttctatta ttatcactta
     6301 ttcaaaagac aaaatacggg aaaatcgaag aaaagctgcg tgcactttct tctggcaatt
     6361 atgaatccaa attgttgctt cttccgatcc caagtgcatc ggacgattta tacatcaaag
     6421 atattgataa ggaaatcact aagataaaag aaaaaatgat tgaagtatct agtgaattac
     6481 aaattgtaac gagccgtccc caatatgtag atggacaaac caaagaagaa attttagaat
     6541 tagaaagaca tcgattagcc cgtgagctgc atgattcagt ttcgcaacaa ttgtttgcag
     6601 caatgatgat gatgtcggca ttgacggagc aagcagaaaa aagcgagaca ccagaaatgt
     6661 ttcgcaagca gttgaaaatg gtagcagaga tcatcaacgc ttcccagtct gagatgcgtg
     6721 cgctgcttct tcatctacgt ccagtcaatt tagaagagaa aagtttaaag caaggtatcg
     6781 agcagttatt gaaggaattg caaaataaaa tccagatttc gctgaaatgg gatgtagaag
     6841 atgtaaaact atctagttcc attgaggatc acttgttccg aatcgttcaa gaattgttat
     6901 caaatacatt aagacatgct aaagccaatg aattagaggt atatttgcac aaaatagaca
     6961 ataatctttt gttacgtatt attgacgacg gaacagggtt taatatgaat gaaacgaaaa
     7021 cgggaagtta tggattgaac aatatcaaag aacgagtagc tggtattggt ggaacagtaa
     7081 aaatcattag ttttaaaggt caaggtacaa gtgtagaaat caaggtccct ttgatgaagg
     7141 aggcatagat aaggatgata aaagttttat tagtagatga ccatgaaatg gtgcgcttag
     7201 gcgtctcttt ttatttatct attcaagaag acattgaagt aattggagaa gctgaaaatg
     7261 gacgacaagg ctatgagaag gcgatgacac ttcgaccgga cgtcatttta atggacttag
     7321 tcatggaaga aatggatggt atcgaatcaa caaaagcaat cttaaaagat tggccagaag
     7381 ctaaaatcat tatcgtaacc agttttattg atgacgaaaa agtttatcct gccattgaag
     7441 caggtgcagc agggtatttg ttgaagacct ctaccgcaca tgaaattgct gatgctataa
     7501 gggcaacgca acgtggcgag cgagtattag aaccagaagt gacaacaaaa atgatggaaa
     7561 aaatgagtcg gcgaaatgag cctgtattac atgaagaact aacgaatcgg gaaaatgaaa
     7621 ttttaatgct gatttctgaa ggaaaaagta atcaggaaat agcggacgaa ttgtttatta
     7681 cactgaaaac agtaaaaaca catgtttcca atatattggc taagctagaa gtggaagacc
     7741 gtacacaagc cgctatctat gcattcaaac atggtttggt gaaataaaaa cgatgataaa
     7801 gaggataatc aaaagctgag aaaataacta ttatttttct tggctttttt acaataatga
     7861 tgcttgcttt tgtttttgta aaggctttgt tatactgaga aaagaagata ctaaaggagg
     7921 aaaacggtga aacaaaattt tgcaattgta ggtcttggac gatttggcgg aagtatctgc
     7981 cgaacactga tcgaagctgg tcaagaagta ctggctattg atagtaatga agatcgggtc
     8041 aatgaatata tgaatatagc cactcatgct gttgtggcaa atgcacagga tgaaatgaca
     8101 cttcgatcat taggcataag aaatttcgat catgtaattg tcgctattgg agaagatatt
     8161 caagccagta tcttagttac tctgatggta aaggaaatgg gcgtaccaaa tattttagca
     8221 aaagcccaaa atgagtatca tgccagagta cttgaaaaga tcggagctga tcgcgtcgtc
     8281 catcccgagc gagacatggg aataaggatt gcgcataatt tagtgtcaaa gaatatttta
     8341 gattacctag agttgtcaga taaatattct ttagcagaaa tccgagtctc caatcctaaa
     8401 tttttcaaca aaacattagc tgaattaaat ttcaggcaac gttttgactt aacagtagtc
     8461 gccatacgaa gagtagatca aacggttatc gcttctcctg cagcagatga atatgttcgt
     8521 gaaaatgata atctactggt tattggagag acaggcgatg tggatattct agacgataag
     8581 atgaatcaat agaaagaaaa gagaaagtag gttgttggga tgaaattaac ggtaacgcca
     8641 aaagcacaaa agtggtttga ctcagaaatt gatctgccag aaacttacgg aatacgtttt
     8701 tttggaaaag tctacggcaa aacagaggtt catgatggtt tttcgattgg aatgtcagtt
     8761 gaacagccag aacatcctgt aaagaaagtg gaaattgatg ggacactttt ttttatcgag
     8821 gaagcagatg aatggttctt taaaggatat gatttacttg ttgattatga tcccaacctg
     8881 gaggagccaa cctatcactt taaaaaacaa taaaaaaaga gagggtgaca caatttttgt
     8941 caccttctct tttttctttt gaaaatattg ttttcagcta ttaatatcct gcagacaatt
     9001 ttacttgatt ggtttgaagc tcatgggtgg caaagtagct tttcagattg gttaaaaaaa
     9061 tagccattaa tttcttttga aaatcaggtg tcaaacctgc aatgtgggaa gtaatcagta
     9121 cattgtccat tttccaaaga ggatgatctt gtggaagagg ctcttcctca aaaacgtcta
     9181 atgctgcaaa ggaaagttgc tggttattta aagcctgcac cagatcttgt gtcttaacag
     9241 aagcaccacg gccaacattg atgaatacag attttggatc aaagtgttca aacatatgct
     9301 gatcaaagag cccagttgtt tcctccgtta gaggtaagat attgactacg aaatctactt
     9361 caggaagaac ttcctttagt tgatttaaag aaaaagtctt ttccattcct tctgctggat
     9421 gaccggatgt attgattcca tagcagttca tgtctaatgc tttgcatttt tttgcaatca
     9481 tttttccaat atggccagtt ccaatgatta gtattttttt cccttggata gattggtaat
     9541 ggaccgatga acctaaccat ttcatgtcac tctgtgcctt ttgtgcttga aaaagaccac
     9601 gagaataccc aaggatgatt cctaagacat gctccgtaat cgattcactg tggatgccac
     9661 taccatttga aagtaaaata tgtttctttg aaaaagtctc aaggggtagc tgatcaacac
     9721 cagctgagat agattggacc catttcaagg tagaagaggc taatagtttt tcttggtagt
     9781 ctgagttcca gcccaaactg atctctacat tttgtagatc ctctggttgt aattctgttt
     9841 taaagatata accaggcgct atagtatgga tttcttcgat aaattcatca cgaaatggac
     9901 gatctgcata aatgattctt tctgacatag ttaatttccc gcctttcttt actctaagtg
     9961 tagcgcatac aagaagaact ttgaagcgcc ttgcttgttt tttgagaaag aaatattttt
    10021 caaataaaaa aggggctgtg acaaaaaaat gtcacaacct ctaaaagggt ctattgaagt
    10081 agaaataacg agttgtcttt atttcttaat tgatcgatat ttttgcccat cctttgacag
    10141 cttgagcaaa aataaagatt cctgcaaaag caatgaaggc gctagtgtca aaagaaggaa
    10201 gaaagaccat caagattgtt gcaattatag taggcaatga aattgaatag atcaatgttt
    10261 ttaaacaatc aagaaaagta gcttttgtta gtcgaaagcg tgcatagaga aaagcagcaa
    10321 tgttggtaaa tagcaaagtg atcagcagat tcagaaaact aggataaata gaaaatataa
    10381 atgtcaggac ttttatccaa agtggtatag atgcttcact taaaaaagaa cggagctgct
    10441 tacctgttaa gttttttaaa gattcattgg tgtagggaag ttctaattgg ttattgttca
    10501 acaaagcaga agtcgtgcct gtattaggaa gagctatgat aagtttgttt tttaacatcc
    10561 cgacactaac aaaattcccc atcaaatcag tagagatgtc ctgttctgtt cgttttccct
    10621 ctggatcaaa tgtgaagata atggagtttg tttggtaaat gaatccttct ttttcttcgg
    10681 tttgaagctg cccgttttgg attgtaaaat caggaatgcg agtagcaatc ttttgcccat
    10741 ccaattgaat gttgtttaag acttgaaaaa cttgaaaaga gattggcaaa gccataatta
    10801 tactcaaaac taaaagatag acaatggctt tccaaaatgg gacatttctc gcctccttta
    10861 ggtctttgaa tcgtataaag gaactgataa ttaattgttt tgttgtcata agtactcctc
    10921 atctagtagt gtcatcactt gcaattctag cgaagtatca agtgaaatac aagtgcttta
    10981 aggaaacagc tgaatgattg gtgaaatatc aaaaaaatgt tattcttgtc taaagactat
    11041 ccaatataaa taaaatggag gaaggaatag tgcctacaca gccacagaga tcatcaaaaa
    11101 aactatttgg agtagtggtt ttgaatgcgg tgatcacttt atcagaattt attggaggga
    11161 ttatgtcagg gagtttgtct cttgtttcag atgctttcca taaccttagt gatacattgg
    11221 caattatttt ttcttacggg gcacaaaaaa tggcccgaaa agaagcaaat aaaaaacgta
    11281 cgtatggcta ccagcgttta gaaatattga gtgctttcat caactcattc atattgatca
    11341 tattatcctt gtttttaacc gttgaagcat tcaagcggtt cacttcacca gaaaagataa
    11401 atagtcattt gatgctaaca gtagcagtta ttggattgct cgcgaatttg ttctcagtat
    11461 tattattacg acaagaagca gatgaaagtt tgaatataaa atctagttat ttgcatttgt
    11521 taagtgatac actgtcttcg gtaagtgtga ttatcggagc aattttgatc cgttttttcg
    11581 atatctactg gatcgatcca gttattacac tgatcatttc gatatatata ttgatagaag
    11641 cgataatggt gatcaaaaaa gctgccgcta ttttgataca aagtgcacct gctatcgact
    11701 atgaaaaaat ggaacaagaa attgaagcaa tcgatggggt aaaggatgtt catcatgtcc
    11761 atatttggca gtatagcgaa aagataatta ttttcgacgg acatattgat tttgaagatc
    11821 agctactaag cgagattgaa aagatatatc ctcgtataat ttctttatta aaattaaaat
    11881 atggtattac acatgtgacg atccaagcag agacaaaggc aaaggatcaa aaaaaattaa
    11941 tttttttaaa taaagatgaa agttattgaa atatagagta tgataaataa gaatttttaa
    12001 taaggtaggt tggctcatga agcagtatcg acagttaaaa ggatatttag aagcaaaagg
    12061 atattgggag atactagtct atctcttttt tggtggtttg gctacgattg taaattttgt
    12121 tagttttgct ctcgcacgcc aatattttga tttaagtatg gccttatcca attctatttc
    12181 gtggttttgt tctgtattgt ttgcttttgt aacgaacaaa ctttgggtat tccattcaaa
    12241 atcaccgaat tttacacatg cacttattga atgcggtaag ttcttcttct accgtatcct
    12301 ttcttacgga ttggacatgg gggcaatggt attgttgatc aatgttatga acagcaatga
    12361 gtatgtggcg aaaatcatca ctcaaattat tgttatcctt gcgaactata ttttcagcaa
    12421 gttgtttatt tttaaagaaa ctgaggtttt tgaagaagaa gtaggtcaaa gtgaaaaaga
    12481 cgactaggca taacaattga agaatttcct tctctttgtt actctttgta atgtagacat
    12541 tattaagaaa acattgagga ggaatttttt tatgacttac acattaccag atctacctta
    12601 tgcatatgac gcattggaac cttatattga cgaagaaacg atgcatctgc atcatgataa
    12661 gcatcacaat acttatgtga cgaatttaaa ttcagcaatt gagaaatacc cagaattagg
    12721 cgaaaaaaca atagaagaat tattatctga tatggacgct attccaacag atatcaagac
    12781 agctgtacgt aacaatggtg gcggacatgc taaccattca tttttctggg aaatcatggc
    12841 accaaatgct ggtggcgaac ctacaggaga aataaaagaa gcgattaatg aagcttttgg
    12901 tgatttttct tcttttaaag aagaattcaa aaaagcagcc gctggacgat ttggttctgg
    12961 atgggcttgg cttgtaatgg aaaatggaaa attagctatt acctctactg caaatcaaga
    13021 ttctccattg atggaaggaa agacaccaat tctaggtttg gacgtttggg aacatgctta
    13081 ttatttgaaa tataaaaatg tccgaccaga ttatattgca gcattctgga atgttattaa
    13141 ttgggatgaa gtaaacaaac gtttcgaagc agcaaaataa ccatttcctc cgtcatatca
    13201 gtcttaaaaa taatttggaa aataaaagag cgaaagcttg ctagcgtttt ctaaattggg
    13261 tataatgttc ttgcaaggtt acttgcaaga acttttttgg aggatataca tttatggaac
    13321 acggaacggt taaatggttc aacaatgaaa aaggatttgg gtttattaca gtagacggcg
    13381 gagatgacgt atttgttcat ttctcagcaa ttcaaggaga cggcttcaag agcctagaag
    13441 aaggtcaaga agtagaattc acgattgttg aaggtgcacg cggacctcaa gctgctgaag
    13501 tgactaaatt ataataattt gttgaataaa gacacgactt cttagagagt cgtgtctttt
    13561 tgtctattta tgaagttttt agattttttg gctaagtaaa tgcatttgtt cacttgacat
    13621 gtcctaacta attatcaagc aaggaacatt ttcttcgtta gtaatggatt ttaaagaaat
    13681 ttcagttttt ggatgttgaa taaaagacca tttgtgaaac cactagtata catactcatt
    13741 accatgtcaa ttctattact ttaaaagaaa atcgttttac tttgaagagg agcatatcta
    13801 tccattaaaa gatgatggta atgcaatcac tagttcgagt cattttaaga gccatgcagt
    13861 gagctggaaa taaaacgaat agaagatggg tttaacaaaa ggaccagtca taggaagaaa
    13921 ttgtcgtgaa atcgaatgat aatctgaacg gtaggcaaag actgttaaaa agatgggaaa
    13981 ggtatgtgcg atcattttac tgcacgatta tttggaaaat accttgttgt tcgctttttc
    14041 tggaaaaaat acataaaaaa agataaaacg attgcgaact gcgtgtattc ggtctttcga
    14101 tctttttcac ggtatggtat gatagttaag aattttgaga aattttaaaa aataataatc
    14161 gttacacaaa aatgtttttt aaagttttct tatgattaaa aagtgaattt gctgattgaa
    14221 cagttatatg agacaatatt ttagaaaatg tgaaacagag gtgtattatg aagcgatggc
    14281 aaaaagttct attaaccttg ttaggggtat tcgttttgct gattgccgga ttatcagcat
    14341 acggaatcag atttatggga gaagcgagcc aaacagtaaa caaaatttct aaaaactcta
    14401 atcgaatatc ctccaaacgt tctgagagag taagcattga tgacaaagaa cctttttcgg
    14461 ttttgctatt aggtttagat accggtggat taggaagaac ggaacaagga cgttctgata
    14521 cgatgatggt agtaacagtt aatccgaaac aaaaaaaatc aacgatcatc agtttggacc
    14581 gagatattta tacgaatatc gtaggttatg gaacggtaga taaattaaat catgcctacg
    14641 catttggtgg tgtcgaaatg gccatggatt caattgagca actgctcgat attcctattg
    14701 atcattatgt aacgatcaat ttggatggca tggaagattt gatcaatgcg gtcggtggca
    14761 tcaaagtgaa taataaaatt gactttactt tggatggtgt ccatgtacca gtaggtgaac
    14821 aaacattgaa tggagaaaaa ggtttagcct attctcgaat gcgacacgaa gatccagaag
    14881 gcgatatcgg tcgacaacgt cgtcagcggg aagtagtgac gaaaatcgtc aataaagttt
    14941 taagtttaga tggcgtaagc aattatagaa aaattttaaa agcagttgag aacaatgtga
    15001 cgacggactt agattgggat gacatgcttg atgtagcgac gaactacacc ccggcgtttg
    15061 aaacaatcaa acaagaccag ttgcaaggcg aaggacaaat gatcaatgat atctactatc
    15121 aaattttagg aaaaaatgat cttctttcga tccaaaatga actgaagaaa caattaaata
    15181 taaaaacaag cgatacatta cctaatttga aaaatgagaa tgcttcaatg atgttctttg
    15241 atgattcgga agatggcgat tcgacaaacg gtgatggatc gaatagtgaa gggtacaccg
    15301 attattcttc ctattcagaa aacacatatg atcagtacca agatccgaat acctattatc
    15361 agcaaacaga agatacaagt cagtactata caccaagtca agatactcaa agttatgatc
    15421 cttacgctgg acaggaacaa aatggttatg gttatgacca gaataatgag tatggaacaa
    15481 caagtgggta ctagaaaaaa atagtttggt taataaagag tgccacctaa attagacaaa
    15541 aaat
//
LOCUS       DAYYEF010000060        15419 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000060 DAYYEF010000000
VERSION     DAYYEF010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15419
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.063"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            287..694
                     /locus_tag="ACHA1B_002249"
     CDS             287..694
                     /locus_tag="ACHA1B_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702993.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="ACHA1B_002250"
     CDS             708..1109
                     /locus_tag="ACHA1B_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702994.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1111..1482
                     /locus_tag="ACHA1B_002251"
     CDS             1111..1482
                     /locus_tag="ACHA1B_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8702995.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1518..1823)
                     /locus_tag="ACHA1B_002252"
     CDS             complement(1518..1823)
                     /locus_tag="ACHA1B_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFM8702996.1"
                     /translation="MTIELEEHLLWFKYDPSEKFVKDFYKVWDSEVFFLAIEDSLLIN
                     LYYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2350..2422)
                     /locus_tag="ACHA1B_002253"
     tRNA            complement(2350..2422)
                     /locus_tag="ACHA1B_002253"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2387..2389),aa:Lys,seq:ctt)
     gene            2803..3372
                     /locus_tag="ACHA1B_002254"
     CDS             2803..3372
                     /locus_tag="ACHA1B_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HFM8702997.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            3359..4219
                     /locus_tag="ACHA1B_002255"
     CDS             3359..4219
                     /locus_tag="ACHA1B_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HFM8702998.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            4409..5113
                     /gene="yycF"
                     /locus_tag="ACHA1B_002256"
     CDS             4409..5113
                     /gene="yycF"
                     /locus_tag="ACHA1B_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator YycF"
                     /protein_id="HFM8702999.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            5118..6953
                     /gene="walK"
                     /locus_tag="ACHA1B_002257"
     CDS             5118..6953
                     /gene="walK"
                     /locus_tag="ACHA1B_002257"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HFM8703000.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            6950..8266
                     /gene="yycH"
                     /locus_tag="ACHA1B_002258"
     CDS             6950..8266
                     /gene="yycH"
                     /locus_tag="ACHA1B_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system activity regulator YycH"
                     /protein_id="HFM8703001.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            8267..9136
                     /locus_tag="ACHA1B_002259"
     CDS             8267..9136
                     /locus_tag="ACHA1B_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HFM8703002.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            9191..10000
                     /locus_tag="ACHA1B_002260"
     CDS             9191..10000
                     /locus_tag="ACHA1B_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFM8703003.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(10103..10732)
                     /locus_tag="ACHA1B_002261"
     CDS             complement(10103..10732)
                     /locus_tag="ACHA1B_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HFM8703004.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            10902..12194
                     /locus_tag="ACHA1B_002262"
     CDS             10902..12194
                     /locus_tag="ACHA1B_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HFM8703005.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(12270..12932)
                     /locus_tag="ACHA1B_002263"
     CDS             complement(12270..12932)
                     /locus_tag="ACHA1B_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFM8703006.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            13157..13441
                     /gene="groES"
                     /locus_tag="ACHA1B_002264"
     CDS             13157..13441
                     /gene="groES"
                     /locus_tag="ACHA1B_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_process: GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HFM8703007.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            13492..15117
                     /gene="groL"
                     /locus_tag="ACHA1B_002265"
     CDS             13492..15117
                     /gene="groL"
                     /locus_tag="ACHA1B_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA];
                     GO_process: GO:0042026 - protein refolding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HFM8703008.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         5229 a         2571 c         3215 g         4404 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa atgtttgact ttaatgaata tttatctatt
     1141 tccaaacaaa ttgaatcaga tgataaatat aattctaaag aatcttatag aagaactgct
     1201 gtttcaagag catactacag tgcttttaaa aaatctgatg agtatttgaa agaaaattat
     1261 gatattattt ataatggaag tagcggaaaa ggaagccacc aaaccgtttg gaatttgttt
     1321 tcaacagtta aggaattgaa taccttagga atacataata gtgggtatag aatgttagag
     1381 aaaagaaaat gtgctgacta tattcctaat gaaaccatta cgaaaacaga tatggcgctg
     1441 atgaatcgag aagcagaaaa aataataaac aaactcacct aatgaatttc aagcgagttt
     1501 gtttgttatt tttttattta atctttgtat ctttctggat caacgaaagt atactttata
     1561 tagtcataac gccgatgatc gctacgtgcg tccggcacat cagtcacgat atcaaacaaa
     1621 aagtatacac ccttcttcat tctagttttc gcagcaggaa ttttgaaata gttcttatta
     1681 gaatagtaga gattgattaa taagctatct tcgattgcta aaaagaaaac ttctgaatcc
     1741 cacaccttat aaaaatcttt gacaaatttt tctgatggat cgtatttaaa ccaaagcaga
     1801 tgttcctcta gctcgattgt catgtttttc acctcaacga aagtatacga actaatgttt
     1861 gttttgtaaa ggataaaaat agggtagcaa ccggtaccca aactagtacc catttatcaa
     1921 aaacgacgaa atttatgtaa atagaaaaat aagaataaac attgatgtat caacatttat
     1981 atatctttag aacaaatgaa aagggtggtt ctcataagaa aaacatgttc gcacttctag
     2041 gcaaaccagg atttgaagac cttgctaaag aattgaacga acgcctgtaa aataaggatt
     2101 tgtcgctaga tttaaaaaat cagtgataga aacatgtttg ctttaaaatg aaactagtga
     2161 tagttttagt gatagtgaac ttaaaaaaag cactcaattt gagtgctttt ttattgttat
     2221 taaaaattaa aaaactaaaa tacatacccg aatttcatac ccgaaatata aaaaatgtca
     2281 tcacgtacat ctttttcgaa actaccgaag tagccaaaga tgtactgatg acgtgggttt
     2341 ggcacccaat gggccgtgag gggctcgaac ccgcgacccg ctgattaaga gtcagctgct
     2401 ctaccaactg agctaacggc ccgtacaaaa agtacttaat aatagtagca ctaagaattt
     2461 taaaatgcaa gactacattt aaagaaaatc agaaaaatct ttacttcctt ataggaaatc
     2521 attcatagat tattcacatt tgctcgctat tatataagca taccaacaaa caaagttctt
     2581 gcaagagaac aaaccctaac acttttttca ttttttactc ctttcccgcc gtctccccgg
     2641 cgggtctcct gttcttaacg ataaaagaca agaaggctta gccttcttgt tttttgtttt
     2701 catggaatcc cgctaatcaa atcacctagt taaagcaact agattgaatg tttatcataa
     2761 gtctgatatc atgtttatga aatgaaaaaa ggagcggtta tgatggaaaa aatgcgtcag
     2821 caattaatgg agtgggggaa ggaactagaa acattccgtc tgcctcactg ggaagaactc
     2881 cctgacttag aactttatat ggaccaagtc agaacgttag ttgatcgtta tctttcacct
     2941 gtgatacaag gagaaaagca tccattgctt acctcttcta tggtaaacaa ttacgttaaa
     3001 ctaggtttga taccagcacc agttaaaaaa agatataaca aagaacacgt agcattttta
     3061 cttgcaatca ctacgttgaa acaagtattg actattcctg aaatcaaaga agggatattg
     3121 ttccaaggaa aaacagtagg aattcgtgaa gcctataatc tattttgcga tgaacaagaa
     3181 gcagctgtgt ggatggtcag ccaattagca caaggtaaat ctcatccgca aaaattcgac
     3241 caggcaaccc ctgtagaata tattgctgta agagcggcaa ctttatcgtt tgcaatgaaa
     3301 cttcttgcgg aaaaaacgat tgttctagaa accgaatatt taaaagagga gaaaacaaat
     3361 gaaaaacaat aaaatcgcaa ttttagtaga ttcaggtacg gatgtgccag aagaattgat
     3421 aaaaaaatac gagatgtata tgatcccatt gaaaattatt tataaagatc aggtatatac
     3481 agataaaatt gacattacct ctgaagagat ctatcaacgt ttgccagagg aaatccctgg
     3541 tacatctttg ccggatggtg agtcgatcac agaaatcttt gagcaaatca aaaaagacgg
     3601 ttatgaaaag gtacttgcgg taacaatttc cagtggattg agcgggacat ataatgtggt
     3661 tcgtttaatt gcacaacagc aagaagaatt ggaagcatat gtactagata cgaaaaatat
     3721 tggtattggt gcaggttttt ctgcgatcca agcagcaaaa tggctggaag aaggagtaga
     3781 atgggatcaa ctgatcagta atctgaatga gttagtcgaa agaacaaaag ttttctttaa
     3841 tgttgcgaca ttggaatatc ttcaaaaagg tggacggatc ggtttagttg cttctattgt
     3901 aggaaccgct ttaaagctta acccaatcat ctcatgtaat gaagaaggga tttattacac
     3961 agtaggaaaa gctaggggac gtaaaaaaag tttggataaa acggttgctt acgtcaaaga
     4021 aaaaatcggt aatgcaaagg tcttcaactt agctgttgcc catggggatg cgaaagaaga
     4081 agcaattgaa atggaagcga gacttaaaag agagttccca caagcaaacc aaatctactt
     4141 tggccagatt tctccggcat tagtagtcca cactggtccg ggattattgg gtgtcggtgt
     4201 acaagtttta gaaggataaa tcaaaaaaag gaaacactga ggtgaaaatc agtgttttcc
     4261 ttttttattg aagttagaac aaaaaataat aaagtatttt gcactttcat tttaattttc
     4321 tcttttgttt tataggcaaa gatgaaacaa aagcagaaat acggtataat gagaaggtat
     4381 gacaataata tataagaggt ggctctttat gaaaaaagtt ttagttgtcg atgatgagaa
     4441 gccgatttcg gatatcgtca aattcaattt agccaaagaa ggctatgatg tttatactgc
     4501 atatgatggg gaagaagcct tggaaaaagt tgctgaggta gaacctgatt tgattttact
     4561 tgatttgatg ctacctaaaa tggacggctt agaagttgct cgtgaggtac gcaaaactta
     4621 tgatatgccg atcattatgg taacagccaa agattctgaa attgataaag tcctaggctt
     4681 agagttaggc gccgatgatt acgtgaccaa gccattttcc aaccgagaat tagttgcacg
     4741 tgtcaaagca aatcttcgtc gcggtgccac ggctgcgaag gaaccagaag aggcagcacc
     4801 tgcggaattg acgattggtg atttgacgat ccatccagaa gcttacatgg tgacgaaacg
     4861 aggagaaaca atcgagttaa cacatcgtga attcgaacta ctcttttact tggcgaagca
     4921 ccttggacaa gtgatgacaa gagaacattt attacaaacg gtttggggtt atgattattt
     4981 tggagatgta cgaacagtgg atgtaactgt acgtcgtttg cgtgaaaaga tcgaagataa
     5041 tccaagccat ccaaattatt tagtgacacg tcgtggtgtc ggttactatt tgcgtaaccc
     5101 agaacaggag taattggatg aaaagaaaag tccgcttttt tcgatcagtc aattttaaga
     5161 tcgctattac ctttattctg attttattga tctcgatcga aattattggt gcctacttta
     5221 tacgtggttt agaacgttcc acgatcaata catttattaa agatatgaat caaacggtgg
     5281 aatcattagc aacaacaatc agcccggaat tgaatcgaaa agataatgca gatgatgaag
     5341 aggtaaatgc gaatatcaaa agatttattg aaaacagtgc gactagcgat atcatcgaaa
     5401 tacgggtcgt tgacgaaaaa gggatcatcc gaggaacaac cgatgtcaat gaacaaagcg
     5461 ctgtgggaaa gaaaaatgat tatgttgata tcaatgattt cacgactaaa cgttatgttg
     5521 ctttagataa cgacgataaa cgggtgaata tcaatgttca accgatcctg tccccgaccg
     5581 gcgatgccgt tatcggggct ctttacgtca aaagtaatat cgaacaaaaa tattcggaaa
     5641 tcaataacac agcagtcatt ttctttactg cctcactaat tgcggcattt atttcaatga
     5701 tcgtatctgt tttagttgct cgttcgatta cacagccgat cggtgaaatg agagaacaag
     5761 ccattcgaat cgctagagga gactacagtc ggaaagtcaa agtgcatgga caagatgaac
     5821 ttggacagct ggctgatacc ttcaatcagt tagctgaacg tattgaagaa gctcaagata
     5881 caatggaagc tgaacgcaat cgtttggata gcgtgctatc ccatatgaca gacggcgtca
     5941 ttgcgacaga tcgcaggggt aaagtcatta cgatcaatga tatggctgtt tccttgctag
     6001 atatcaaaaa cgaggaagca atcggacaat cgattttgac acttttagat atcgaagaag
     6061 aatatacgtt gcggaaatta ttagaagatc caaacgaaat ggtacttgac cgttcaacca
     6121 gtacattgga aagtgatcag atgatcttgc gagtagactt ttctatgatc cgtcgcgaat
     6181 caggttttat cagcggatta gtagctgtct tgcatgatgt gacagaacaa gaaaaaacag
     6241 aacgggaacg tcgtgaattc gtctctaatg tttcccatga acttcgtaca ccgttgacaa
     6301 gtatgcgtag ttatatcgaa gcattgagcg aaggtgcgtg gaaagacgag gaagtagcac
     6361 caaatttttt gaaggtaacg ctagatgaaa cagaccgaat gattcgaatg atcaatgacc
     6421 tcttaaatct atctcgcatg gatacaggta atacccagct tcaattagaa tatgtcaatt
     6481 tcaacgagtt agtgaatttt gttcttgacc ggtttgatat gatggtggga aatcaggaaa
     6541 aaaattataa gatccgtcgt gaatttacgc aaagagatct ttgggtcgaa gtagatacag
     6601 ataaaatcat ccaagtagtc gataatatca tgaataacgc gatcaagtat tcaccagatg
     6661 ggggaacgat tacttgtcgc ttattagaaa cgcataataa cgtggtttta agtatcaccg
     6721 atcaaggatt ggggattcct aaaaaagatc tgaaccgagt gttcgagcgg ttctatcgag
     6781 tagataaagc acgtgcaaga gcacaaggtg ggacaggact tggattagct atttctagag
     6841 aagtgattaa ggcgcatcga ggcgctattt gggcagagag caaggaagga aaagggtcga
     6901 ctttttatat ctcgctgcca tatgaacctt atgaggagga atggtgggaa tgagaatctc
     6961 tgaaaaagtc gttcgtatag gactcatttt gatggttgcg ttaagcatat acttctctta
     7021 tgcaatctgg ctgagcccag caggaaaaag ttcaatcaac gtagatgaga caaacactca
     7081 aatgatcgag tctcaaagca atcgaaaaac ttccgaagtc tttcttccgc ttcatgttac
     7141 atggcaccat tcgggaatga tccaagaaac caacagtgaa aatctcgtgt accgattgca
     7201 attgatcatc gataaagcaa gatttggaaa gctttctgaa gtagtttcag gagacaaatc
     7261 acagtttgaa caggtgaaaa atctgaactc tggttttgag ttggcctata atgcgccttt
     7321 tttgctaaga gaatacaagg aagcatttga tttagattta gatgtgtcga acttggcaaa
     7381 agaaagcgaa aatatgtatt ttactagaat acaattcgat caaggaaata aaaaaatccg
     7441 atttttgaat tattcgaacc atctcgtata tgaagcaaat atttcgttga attggacaga
     7501 tatcaataaa gaattaacag caaaagacac aaaatggaca gaaatgacaa cagaaccatc
     7561 gacgatcgac acgcaatatg ctacgaaaca ttcgatcaaa ctgaaaaagt atagttatat
     7621 cctgtcacag caaccctata cactttttag aaatgctttt ttccagaaac cagatagcgt
     7681 gaaaaataat gatgaaagca atgaattgat tttttacggt gggaatgaaa caatgtctat
     7741 ccattcggaa acgcaagtag ttgattttcg tggagagctg ccagagaaaa aagaaaatgc
     7801 tagtgtattt tctgaaagtt tcccctatat tagcaaatta ggcagttctt tagggaacct
     7861 cagatatttt gaccgcagtg acaatacgat cgattatcgg atattcgtgg aaggcttccc
     7921 ggtttttggg acagacagca gaggacagat tggtgtggaa gttggcggtg aaacgaatgg
     7981 ttctgtgcaa gtgaatatcc aaaccagttt gaatacgatt caagtgccga taccttcaga
     8041 cgaagaagta gaacttgcaa gtacgaatga aatcatccag cagttaaaag ctaagggagc
     8101 agatagcaac aagattggtt cagtgatcgt tggctataca tggcaaaatg tcaaagaaac
     8161 gaatcgtgtc gttgatctct tacctgaatg gtatgtgaaa tataaagata actggtattc
     8221 agctaacgac cttctggaaa aattacctgg attggaggcg aattaattgg atttcaaaaa
     8281 aatcgaatgg atatttttcg tcgctttttt agggttgaat gtgtttttat tcagcagtta
     8341 tcatgacgcg gtataccaag aaaacaatgt cattcgctct aatcagactg aatcaatcca
     8401 acaacgtctg gctagcgacg atatcactta cacggggaag atttcgtctg agaacaagca
     8461 aggctattat cttagcgcgg agcagaccaa tcttagcact tcattagcga attatcgcaa
     8521 ggctggtaaa agcggcttgc tggcaagtgg tgtgttttta gacggtgatg ttttgacgaa
     8581 atctttatcc agttcagatg ctgaaaagaa cgtgatcgat ccagataaaa ttagtagttc
     8641 cttggaagat tttttatcta acaaagacaa tattttattc ggtaatgatt atgtgtacac
     8701 gaaaaacttt tctcatttag aagaagaacc actagaaatc caagcaagcc aagagtatga
     8761 aggcatccca ttcaatgatg atacagcaaa aatcgttctt tctttagaaa aaaacgataa
     8821 tgattatagc atcacgaaat acatgcagac gcatttatct gatatcgagc agctgcgcga
     8881 aaagacggaa ctgtatacgg aagaggaagc aatcaataca ttgtacatca ataacaaaat
     8941 accaagagga tcaaaaattt tatggcgtca gctagcttat tcctgtattc tgaaagtccg
     9001 ggaaaaaaat gtgtatgttc ctgtttggca tgtagcgatc gaaacaagcg ataaagtggt
     9061 ccaaattgag agtgtcaacg ctttcagcaa tacgatcgtg acaaacaata ctgtaccaaa
     9121 agtggaagat caataaaaaa gcgagtataa tgaaaaaagt ttacaaagta agaagggaag
     9181 taggagtcaa atggctgaag aaaaaccagc ttttaaaatc agtatcctag caagtggaag
     9241 ttcgggtaat tcactttata tcgaaagtga aaaaaaacgg cttttggtcg atgcaggact
     9301 tagcggtaaa aaaatcactt ccttgatggc tcaaattgat cggacaccgg accaattaga
     9361 tggaatactt gtgacgcatg aacatcgaga tcatatacat ggcgtgggtg tcttggctcg
     9421 taagtatcat ttggatgttt ttgccaatca gcagacttgg gaagcgatgg aaccactgat
     9481 tggaaatgta ccagtggaac aaaaacatct atttgagatg gggaaagtca gaacattcgg
     9541 cgatatcgat attgagagtt tcggcgtctc ccatgacgca gcggctccgc aattttatcg
     9601 tttccataaa gaaaatcggt cattcgtcat gttgacggac accggatatt gcagtgatta
     9661 tatgcgaggt gtcattgaaa atgccgatgg ttatttgatg gaaagtaatc atgatcttga
     9721 gatgttacgc atgggacctt atccgtggaa tttaaaacag cgtattttag gagatagagg
     9781 acatctttcc aacgaagacg gtgcacttgt catgactgat gtgatcggta atcggaccaa
     9841 acgaatctat cttggccatc ttagcaagga aaacaatatg aaagaacttg ctcatttaac
     9901 aatggaaaat gttttgaaag aaaaagattt tggcgttgga catgattttg aaatctatga
     9961 tacagatcca gatgaagcaa ctgagctatt ttcgatttaa acagttcaat caataaaaat
    10021 ataaaaagca gaagataaaa tcaatcaggg ttggttttat cttctatttt tattttttta
    10081 gcatattaaa aaaataaccg tattatcgac tgactacact gatgtgctgc ttttcatgtt
    10141 tctcatccag tatctcatct actaatgcaa tcgcgtaatc tgccatgctg atcgtactgt
    10201 cgccagcagc gtttctttgt aaataatcat cacttaacaa ataagtacct gtacgtttgc
    10261 catgtggatc aaataaagaa gctggactga tataagtcca atgtagattt ttagattgtt
    10321 tcaattttaa caatccttcg tacatattga aagctgttgg atagaagggt gcatttttag
    10381 gtacttggtc aatcatacga gtcgtctttt ctgtatctaa gaataacgaa gaggcacccc
    10441 caacgacaat taagcgtgta tcggttcctt caagcatctc aatcaaatgg gacaaagaag
    10501 tttgatgcat ttcttctttt cctttgggag cgttgaaagc atcaacgaca acatcaaaag
    10561 atgcaagatc agtagttgtc aactcaaata aatccttttg tataaacgga acatctgatg
    10621 gcaatttttc tggatgacgc acgattgccg tcacgtctaa atctctggac aatgcttcgt
    10681 ctaaaataaa tgaacctgca tggccagtag ctccaatgag tgcaattttc ataaaaaacc
    10741 tcctttttta ttcctgtcca ttgtaagcag ttgctgaata ttcgtcaaag aatccgattt
    10801 ttgaaaagct cagtgcgcat tcctttcatg gttcgtgatc attgggtata gttaaattaa
    10861 gaaaactgat tgataaaaat agaagttgaa ggagataaga aatgaaagag tggttagatc
    10921 gtgccttttt accaatgata acatctgttg tgaatcttag acccttaact gctttgcgta
    10981 atggaatgac ttacacgatc ccaataatta ttgttggctc gctgtttttc ttatttgctc
    11041 attttcctgt ggattacatc gctcagtgga tagacaaaac aggattttct atgtatttta
    11101 cacaagtata ccaggctaca tttgatgtga tagccttttg gatcgttttt gccattgcat
    11161 acgcttatgc aaaagaagaa gacatcgatc gcttaccagt cggcataaca gccttgtctg
    11221 cttatctact gcttattcag ccactaaata ctcagataga tactgtctgg acaggtgctg
    11281 aagggatact aggagcagtt acaactgggc tcatcatcgg atggggctat gcacgtttag
    11341 taagacttgc gaaagggtgg aagcaaagag agaagatacc tgaaaatgtt tggcagtctt
    11401 ttacttcatt gattccaatc attgttatag tcacttttac gcttatcggt tcagcggttt
    11461 ttcaacagtt gttcagaatg actgttgttc aaggagtatg gacatatgtc cagcttccca
    11521 ttcaatcgtt catagacacg ttgtttggtg tgcttttatt aggttttttt gttccgtttt
    11581 tatggttatt tggtcttcat ggatctgcga tggtcaatgg gttggttagt cccgtcttgc
    11641 aagcgaattc attagcgaat gcagaaatct tagcctcagg acaagagttg acggtggcaa
    11701 atggcggaca tatcgttact cagcaatttc tcgatcagtt catgacggtt acgggtgctg
    11761 gattgacgtt aggggctgta ttttttatga cggtttttgc gaaatcgaag aaatacagag
    11821 aattaggaaa tcttgctctt ttaccagcct ttttcaacat caatgaatca attatttttt
    11881 ccacaccgat cgtgatgaac ccgatgatgg ctgttccttt tattttcgca ccggtcgttt
    11941 caggattgat tacctattcc gctttatatt ttggattcgt tcctttattt acagcagtcc
    12001 aagtcccttg gacaacaccg ccgatcctct cgggtttctt agtaggcgga gtgcctgcag
    12061 cgattttaca aggtatcgtg ttgtcaatta gttttttcat ttatttccca tttttgaaaa
    12121 aaatagattc tgcaaactgc aaaaaggaaa gacagacaaa aaatgatgga gcagcagaaa
    12181 agatgaacga ctaaaaaaca aaaatactcc tgtcgcttta gattgggaaa atcaccaatc
    12241 taggatgaca ggagtattta tagtcatgtt tatactagcc ctttttggac agctaattga
    12301 acaagaacaa ctaatgtgtt cattcctacg tgtgtgatca tcgatgtcca gatccgacca
    12361 gttgctttgt actctaggct gaagaagaaa cctaggaaaa agtagattag cagatgacca
    12421 tcattatgag caaacgcaaa cagcaaagag ctgatcactg ctccgaccca aaaatttgaa
    12481 tatcgactga tgatccccag tatactgcgg cggaatacga actcttccat gatgggtcca
    12541 gcaacagttg tcgccaaaat aaaagcgggt gcttccatga tcatctggat gatattttgt
    12601 gtattctcgg aaggggttgc tttgccaaac aatacagatt ctaacatgac agcgatgctt
    12661 tgcagaatca atgcgacaaa gattccaacc aatccataaa taacaatctt tggagcagaa
    12721 gcttttttta ccgctgattc gatcgctaag ggttcacgtt gcttaaaata aaaaatagct
    12781 aggacaacgg cgcctagtat atacatgact gcagttgctg tgatcaattc agacgtagat
    12841 tttacaagtc ctatcgaagc taggatcaag ggtgagataa aaattagacc atagcaaaaa
    12901 atgctgagga agctatattt ttttaaagac atgtaattcc tccttttaag ggataacaag
    12961 catgcaaggc aagcttatat cgattgattt caattatatc ataatttcaa taagcagctg
    13021 tcagaataaa atttcttttc tttgatttaa aagcttgcaa aaaagaggga gaatgagtat
    13081 tattaaaaat gtaggttagc actcgaaggt taagagtgct aacagattaa aaaaagagtt
    13141 atcggaggga tttatcgtgt taaaaccatt aggtgatcgc gtcattatcg aagtcgcaaa
    13201 agaagaagaa aaaactgtcg gaggaatcgt tttagcttct gctgctaaag agaaacccca
    13261 aactgggaca gttgttgcag tcggtgaagg ccgtttgtta gaaaacggtg aaaaagttcc
    13321 tgccgctgta aaagcaggcg accaagttat gttcgaaaaa tacgccggta cagaagtaaa
    13381 atacgaagga aaagaatatc tgatcgtcgc aggaaaagat atcatggcga ttgttgagta
    13441 aatttggaag ataaaaaaat aatcaaaaat aatcaatgag gtgaatcaat catggcaaaa
    13501 gaattgaaat ttgcagaaga cgcacgcgca gctatgttac gcggggtaga taaattagca
    13561 gatacagtga aagtaacatt aggacctaaa ggccgaaatg tcgtactaga aaaatcttac
    13621 ggctctccat tgatcacaaa tgatggtgtg acgatcgcaa aagaaatcga attagaagat
    13681 cattttgaaa acatgggtgc aaaacttgta tcagaagtag catcaaaaac aaatgatatt
    13741 gcaggagacg gtacaacgac agcaactgtt ctgacacaag caatcgttcg cgaaggttta
    13801 aaaaacgtaa ctgcaggtgc taatcctcta ggcattcgtc gcgggatcga attggcaaca
    13861 aaagcagcag tcgaagaatt gcataatatc tcaactgttg ttgattcaaa agaagccatt
    13921 gcacaagtag cagctgtttc ttcgggttct gataaagttg gacatttgat tgctgatgca
    13981 atggaaaaag ttggaaacga cggtgtcatc acaatcgaag aatcaaaagg gatcgaaaca
    14041 gaactagatg ttgtagaagg tatgcagttt gatcgtggtt acttatcaca atatatggta
    14101 acagataacg acaaaatgga agctgttcta gaaaacccat atatcttgat cacagacaaa
    14161 aaaatctcta acatccaaga tattctgcca ttgttagaac aaatcttgca acaatcacgt
    14221 ccattgttga ttattgctga cgatgtagat ggtgaagcat tgccaactct tgtattgaac
    14281 aaaatccgtg gaacattcaa cgtagtagct gtaaaagctc ctggtttcgg cgatcgtcgt
    14341 aaagcaatgc ttgaagatat cgctattttg acaggtggta cagtaattac tgacgatcta
    14401 ggtttagaat tgaaagatgt aacaatcgaa aacttaggaa atgcttctaa agttgttgta
    14461 gataaagaca atacaacgat cgtagaaggt tctggagaaa aagaagcaat cgaagctcgt
    14521 gtgcaattga tcaaaaacca aattgctgaa acaacttctg attttgaccg cgaaaaatta
    14581 caagaacgct tagctaaatt agcaggtggt gtagctgttg ttaaagttgg tgcagctact
    14641 gaaacagaat tgaaagaatt aaaattacgc attgaagatg cattgaatgc tacacgtgcc
    14701 gcagtagaag aaggaatggt ctcaggtggt ggtacagctc tagtgaacgt tatcagcaaa
    14761 gtttctgctg tagaagcaga aggagacgtg gcaacaggta tcaagatcgt tgttcgtgct
    14821 ttagaagaac caattcgtca aatcgctgaa aacgctggtt atgaaggatc agtgattgtt
    14881 gataaattga agaacgtgga actaggcact ggtttcaatg ctgctactgg agaatgggta
    14941 aacatggttg aagcaggtat cgtagaccca actaaagtaa cacgttctgc cttgcaaaat
    15001 gccgcttccg tttctgcctt gttattaacg acagaagcag tcgttgcaga taaaccagaa
    15061 ccagcagcgc cagcagctcc tgcaatggat ccatcaatga tgggcggtat gatgtaagaa
    15121 aaagcaactt gcttatctac aactgatcat tagtgaaaga cagataaaaa gaggctggaa
    15181 cagaagcgtt taactccaag aaataagaag aaattcacgg aaattgcttt tcaaattttt
    15241 gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgctgtttat acgtgtttag
    15301 agcgtgagac aaaagtgttc tttacttttg tcccacgctc ttttttgtgt gtaattataa
    15361 tgaaaatagt tatttttaat agttataata ttttatctat taaaagtaaa tatccattc
//
LOCUS       DAYYEF010000061        15139 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000061 DAYYEF010000000
VERSION     DAYYEF010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.064"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            4..2376
                     /locus_tag="ACHA1B_002266"
     CDS             4..2376
                     /locus_tag="ACHA1B_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArdC-like ssDNA-binding domain-containing
                     protein"
                     /protein_id="HFM8703009.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..3897
                     /locus_tag="ACHA1B_002267"
     CDS             2437..3897
                     /locus_tag="ACHA1B_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HFM8703010.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3908..6112
                     /gene="topB"
                     /locus_tag="ACHA1B_002268"
     CDS             3908..6112
                     /gene="topB"
                     /locus_tag="ACHA1B_002268"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFM8703011.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6128..6277
                     /locus_tag="ACHA1B_002269"
     CDS             6128..6277
                     /locus_tag="ACHA1B_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703012.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6352..6945
                     /locus_tag="ACHA1B_002270"
     CDS             6352..6945
                     /locus_tag="ACHA1B_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HFM8703013.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6958..7857
                     /locus_tag="ACHA1B_002271"
     CDS             6958..7857
                     /locus_tag="ACHA1B_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HFM8703014.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7860..8357
                     /gene="ssb"
                     /locus_tag="ACHA1B_002272"
     CDS             7860..8357
                     /gene="ssb"
                     /locus_tag="ACHA1B_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003697 - single-stranded DNA binding
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HFM8703015.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
     gene            8723..8983
                     /locus_tag="ACHA1B_002273"
     CDS             8723..8983
                     /locus_tag="ACHA1B_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703016.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            9428..9634
                     /locus_tag="ACHA1B_002274"
     CDS             9428..9634
                     /locus_tag="ACHA1B_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HFM8703017.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            9655..9885
                     /locus_tag="ACHA1B_002275"
     CDS             9655..9885
                     /locus_tag="ACHA1B_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703018.1"
                     /translation="MTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLVEDAPTML
                     FEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            9901..10338
                     /locus_tag="ACHA1B_002276"
     CDS             9901..10338
                     /locus_tag="ACHA1B_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703019.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            10331..11038
                     /locus_tag="ACHA1B_002277"
     CDS             10331..11038
                     /locus_tag="ACHA1B_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703020.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            11202..11402
                     /locus_tag="ACHA1B_002278"
     CDS             11202..11402
                     /locus_tag="ACHA1B_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703021.1"
                     /translation="MNKIIPLLFVLCIGEILMRHGAAVHLNFVVFLGILVFCLIFWRF
                     VLALVSLLFKLIAAIFFIGLFR"
     gene            11418..11597
                     /locus_tag="ACHA1B_002279"
     CDS             11418..11597
                     /locus_tag="ACHA1B_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703022.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            11922..12185
                     /locus_tag="ACHA1B_002280"
     CDS             11922..12185
                     /locus_tag="ACHA1B_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HFM8703023.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            12179..12529
                     /locus_tag="ACHA1B_002281"
     CDS             12179..12529
                     /locus_tag="ACHA1B_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HFM8703024.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(12553..13167)
                     /locus_tag="ACHA1B_002282"
     CDS             complement(12553..13167)
                     /locus_tag="ACHA1B_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703025.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            13481..13903
                     /locus_tag="ACHA1B_002283"
     CDS             13481..13903
                     /locus_tag="ACHA1B_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703026.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            13913..14116
                     /locus_tag="ACHA1B_002284"
     CDS             13913..14116
                     /locus_tag="ACHA1B_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703027.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            14327..14911
                     /locus_tag="ACHA1B_002285"
     CDS             14327..14911
                     /locus_tag="ACHA1B_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703028.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         5571 a         2452 c         3061 g         4055 t
ORIGIN      
        1 aacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ctagtacgat tgcaaaatga attaaacgaa caaattgaaa agatgtttga acaccaaaaa
      121 atgacgaacg gtcaaccaat gaacgacaag aggaatggcc gttcatggtt taaccagcaa
      181 gaacgaatcg aaaataaagt ccaaagtctg agagaagaga tcaagcaaca agaagaatac
      241 gtggaaaagc ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcgg ctttttcagc cgccacgatc cgaaaatacc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctaga
      661 ccaactgatt ctatgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt cgaattgatc
      781 gatcaactca aaacattgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaggaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaaccaat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaagggt tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctatacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagct
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg cagaaaaaga agggttgatt
     2881 gccgaactaa agccaaaata tgaacggcaa aatttcttag ttcgagacga tcgtttagat
     2941 catgcggtcg cctttttatg gaaagatcca cagacaaaag agacagtagg ggcgagttat
     3001 caaggaacgt tcattgatta tgaacgtttt ggtgagagag gcacatataa gcatatagat
     3061 aaaaattcga cagcgaatca tggctttaac ctaaagatcg gtgaccctaa gcagataaaa
     3121 ttttttgaga gtagtattga tttacttagc tatgctgcac tgaatcgtga tcagttaaac
     3181 gatacgtggt tagtctctat ggaagggtta aaacaccatg tgatcagtca ttattttggt
     3241 gaggcagtat ctgaattgag aaagaaacaa gcctttcctc aatccatcga gatttgtgtg
     3301 gataatgacc gtgcaggaca tattttctac gaaaaagaac aattaatggg cgcagtcgat
     3361 ccatttacga atcagaaagt acgttgtgaa cgaggaatcg ctaatgattg gcaagtgcca
     3421 aaagaataca aaatcattta tgaagaagtc gcaaaagaag aaaaggtcac accagaagct
     3481 attatggcca tacacaagac agaaaacaat ctgcaattaa cgaaccaact ggtttccgct
     3541 cacaaagtaa atgcgttttt tggccagcag ctttctgtta acgattcaat agaagccatt
     3601 aatttgaaag atatttgtag agaagtcgca aaagaattaa aagtttgtga acgcgtggat
     3661 ggtacgtacg attttgatcg tttttatcaa gaaaaagggg atattaatgc gcagattctt
     3721 ttctcttata aagcagaaca atactacaaa ggctataaaa atcatgaaca tgaatttgta
     3781 cctgaagtaa aaaaggactg gaacgatcaa ttgaagcatg agatccagca acaagaaatc
     3841 agaaagcaaa aacgtgccat gttgtttcaa caaggcagac aacaagaaag ggagtgaaat
     3901 cgtcatgatg aaaaccgtta ttttagcaga aaagccgtca caagcgaaag cttatgccga
     3961 tagcttctct aaagccactc gaaaagacgg gtattttgaa atccaagatc gattgtttcc
     4021 tggtgaaact gtgatcacgt atggttttgg tcatttagtc gaattagatt cgcccgatat
     4081 gtacgatgaa aattggaaac aatggtcatt agaacatttg cctattttcc ctacacatta
     4141 tcactatcat gttcctaaag ataagaaaaa gcaattcaag gtggtgaaac agcaacttca
     4201 atcggccgac accattatta ttgcgacaga tagcgatcgt gaaggggaac tgatcgcttg
     4261 gacgatcatt caacaagtag gcgccgatca aggaaaaacc tttaaaagac tttggatcaa
     4321 ctccttagaa aaagaagcca tttatcaggg attccagcag ttacgagacg caaaagagac
     4381 ctatccaaaa tttgaagaag cacaagcacg tcagatcgcc gattggttaa ttgggatgaa
     4441 cggtagccca ctgtatagtt tactcttgca gcaaaaaggc ataccaggaa gcttttcctt
     4501 aggcagagtc caaaccccaa cgctttacat gatttatcaa ttgcaggaaa agattagaaa
     4561 tttcaagaaa gaaccttatt ttgaaggaaa atccgaagta atcgctcaaa atggcgcatt
     4621 tgatgcgaag cttgatccga atgaaaccca agcgacgcaa gaagcatttg aagattattt
     4681 aaaagaaaag ggggttcaat tgggaaaaca gccaggcatg attcgccaag ttgaaaccga
     4741 gaaaaaaagc gcggcaagtc cacgtctttt ttctctatcc agccttcagt ctaaaatgaa
     4801 tcagctcatg aaagctagtg ccaaagacac tttggaagcc atgcaaggct tgtatgaagg
     4861 gaaatatcta agctatccgc gaacggatac cccttacatt acggaagggg aatatgcgta
     4921 tctgttggac cacttagacg aatacaagca ttttttgagg gctgaagaaa tttcgactcc
     4981 tattcataca ccgaatagta ggtacgtgaa caacaagaaa gtccaggaac attacgcaat
     5041 cattcctaca aaaacagtta tgacagaagc gacgtatgaa agtctgacac ctttacaaca
     5101 agcgatttac gagcaagttt taaaaacgac agtggcgatg tttgcggaaa aatataccta
     5161 tgaagaaaca acgatcttga cgcaagtcca gcagcttcag ttaaaggcaa tcggaaaagt
     5221 accgatagat ctaggttgga agaagttatt tggcaaagag agcgacggaa aagagaagga
     5281 agaagagccg ctacttccta aagtgacaaa aggagaaatg gtgacggtag atctacaagt
     5341 ccttgaaaaa gaaaccaagc caccacaacc ttataccgaa ggtacgttga tcactgcgat
     5401 gaaaacagct gggaaaaccg tggatagtga agaagcgcaa tccatattga aagaagtgga
     5461 aggaatcggt acagaagcga cacgggcgaa tattattgaa accttgaaac aaaaggaata
     5521 tatcaaggta gagaaaaata agcttgtggt gacgaataaa ggggttttgc tttgccaagc
     5581 tgtggaaaaa gagccgctgc ttacgagtgc cgaaatgacc gccaaatggg aaagctactt
     5641 gttaaagatt ggagaacgaa aaggaacaca aaccactttt ctagccaata tccaaaagtt
     5701 tgtctctcac ttattggaag tcgtcccagg acaaatccaa tccattgatt ttggatcgac
     5761 gttacaagaa gtgaaagcag ccagtgaaaa gcaagaagcc gcgcgtcatt taggaatttg
     5821 tccaaaatgc caggaacaag aagtcttact ctatcaaaag gtggcagctt gtacgtctga
     5881 agcctgtgat tttaaattat ggacaacgat tgccaaaaag aaactcacag cgacacagct
     5941 gaaggagatt attcaaaata gccgaacaag ccaaccagtg aaagggttaa aaggtcagaa
     6001 gggttcgttt gaagcaacga ttgttttaaa agaagacttc actacaggct ttgaattttc
     6061 tgaaaagaaa aaaacgaact tcaagaaaag aacacgacgc acgacaaaat aatggagggt
     6121 taatcttatg cgtaatacaa cacacaaaca acaagaaatc gaaaatcaaa aagccaaaat
     6181 tcgttcagaa caagagaaat tacgtgccag taaaagaaga cttcagcaat taaagaacca
     6241 gcaacggatt caaaaagaaa tcgaattaga tcgatagaca ttaaccttgt tacaaataca
     6301 ctatcatgat atatttaatg tagtgtattt gtaacaaaag gggggaagta aatgcaagag
     6361 aaactgaaag aattgttggc tattcgcgat ggaaatttat ctatgaagga agccagaaaa
     6421 ttaggaatcg cagcaaccac tgtacaaaga ttggtgaatc aaggaaaatt gatcaaagtt
     6481 gatcgtggtt attatgtaga ggatggtcat ggaatagatg atttattttg gcttcagcaa
     6541 cgtttttcca ggggaatctt ctctcatgaa acgactttag atatttacca gctttctacg
     6601 aatatgccga aattcattca cttaactttt ccccatggat ataacgttga tcgttcaatt
     6661 acaaaagagc agcagttaca atttcatttc gtgaagaaag aagtttatga actaggaaaa
     6721 gtagagggaa cttcctttca aggaaatcct attactatgt atgataaaga gcgtacactt
     6781 tgtgatattt ggaatccgag atatgaaatt gaatatgaaa tgaaattaga agcattaaaa
     6841 gagtacatgg aagacccatt gagagatcca agtaaattaa gagattacat gacaaaacta
     6901 catgtagaaa aagaaatgaa ataccacatg caaagcttat attgatggag gaaaaagatg
     6961 acaccgacac aatttgcagc aaaaacaaga aatttagcaa agaggacagg attaaatgca
     7021 cagttagtac aacggcattt tatgatggat cgtttaattg aacaaatttc tgaatctaag
     7081 tataaaaatg atttcatttt gaaaggtggc tttttattag gatcaaaata tggaatcgat
     7141 agaaggacga caattgatat cgacacgaca tttagaaata gcaaattaac tgaagaaaaa
     7201 ttgaagagta tttttaatga tttaactagg aaacccacga aagaaggtat tgttttctct
     7261 attcaaggaa tgaaggaaac aagagaagcc gatttttatc ctggatttca aattaaattg
     7321 gtggctaatt tagagaaagt acgtgtgcca tttaaaatgg acgtgacaac aggagattct
     7381 atttatcctg aagtagatac acactatcac caattaatgt ttgaagataa aaaggtggag
     7441 attccagctt atccaacagc acaaattatt gcagaaaagc taagtgctac gttcagcttt
     7501 ggcacagata attcgagagc aaaagattac tacgacttat ttaccattcc gaaactagaa
     7561 aatatcgata cgaaagagtt atacaaaagt gttcgaaata catttacaaa acgtggggat
     7621 acaaaaccgt tgtcctttta ttatgaaaga gaaatggata agatcatagg aaatgactat
     7681 ttggaaaagc agtgggaaaa atatcgctca gttaacacgt ttgcgaattc catttcattt
     7741 acagatacag tcaacgaaat tgatcaccta atgaaaagtg tgatcaaaat tgaaaatcaa
     7801 gaaagaaaac ggcagtttaa aagatcacaa caaatgaatc aagaaatgga gagataaaga
     7861 tgatcaataa tgtaacttta gtaggacgct taaccaaaga tccagattta cgttataccg
     7921 cgagtggtac tgcagtagcg acttttaccc tagctgtcaa ccgaaatttc acgaatcaaa
     7981 acggcaatcg agaagctgat tttattaact gtgtgatttg gcgcaaacca gcagaaacaa
     8041 tggtgacatt agctaaaaaa ggtagcttga ttggtgtagt tgggcggatt caaacgcgga
     8101 cttatgacaa ccagcaagga caacgtgtgt atgtgacaga agttgtggcc gataatttcc
     8161 aactattaga aagcaaagca gcgacagaaa gccgtgcgca cgctgatcaa tcgtccacca
     8221 gtccaagcac caccactttt gaacaacggg atacagcgac gcctaataac aatggattga
     8281 acgctttaca gaatccattt gggaatccat ttggtggaca atcaatcgat attagcgatg
     8341 atgatctacc gttctaagta gcattttcta ttggttgcat ttgctacggt ttatgttata
     8401 atttagtcaa caaaaagaat tttcaatcta taaccaaaaa ccactagctg gcgggctagt
     8461 ggttttcttt tacgtttcta ttataagaat taacgggtag gcttactgtc tttcttggca
     8521 aatttacaat caagccattt gcagatatag tgcgcggcta cttctgccat gattgcaaaa
     8581 acaaaatcaa aaagaatttt caaacctata acctcctccc cttgccagat taggccgggg
     8641 tagcagacag caagactatt atagcataat tgaaatatcc aaatgattgg atttttgcta
     8701 taattttagc gaggtgattg tgatgaacaa atatgttggt ttgcttgata aaatccgagt
     8761 aataaaaacg caaccgttat tggttcgctt tactttacaa acgattcatg aatcgattaa
     8821 ttgtgtagtt gcagatattg aaattatcga taaattgcta attatggatg atggaaaata
     8881 caatattgcc gtcacaggtc acttcaataa acgaaatcag ctagttattg ctagcatgta
     8941 tgttagaaat cccgatcatt ttacgcgatc gatgggcata taaaaaaaga agagttgcaa
     9001 tcctaatgta ggactgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc
     9061 tttttaggaa ggcgcgagcg ccttctcaat tgaaaaacct ctctcactcc aaccgccacc
     9121 gccgttcgag aagaaaggaa gtgaacgttg cacgttcact aagataaagg gtcttgcaaa
     9181 gcaagacaaa atagaaaaaa cttcctctca ccaaaaggtt cgttcctgtt cgttatctct
     9241 ttattgattt gccagaccgg caacaagttg ccttttatca ccaaaaagcg acaaggacaa
     9301 gggtaaatgg cacgctgcgc gcccttgtcc ttgtcgcttt tcgttgattc attctggcca
     9361 acaaatcaat aaagaaagaa ctaacgaaag gaagtaaaac ctttcctaag aggaggcaga
     9421 atcaatcatg cgaaagaaat ttgattattg gggtgttccc ttcagcgaat tattcccaaa
     9481 ctatcatgca ccacatactg tcgaatgcga ttgtggacaa agagcgaaat gtatcaaaag
     9541 ctatcgtttg tatcaatgtc caacatgcgg aaaaaaatac accttgtctt atggcgatta
     9601 tattttgatt gatgagaaag gaaagaaacg ctgatgaaaa cataacataa attattgact
     9661 gtaaaagaag tcgttcaaat tttggtggac aaagaagtca tttctgaaaa agtagcagaa
     9721 gctttactta ttccgcggta ctggacgata gaaacccctt tagtagagga tgcaccgact
     9781 atgctatttg aagacctagt gaagattgca ggatatgaac tgcattatca agaaaacatg
     9841 gaaacttatg aaaacgaata ttggttaacc aaattagaga actaaaaagg agaaaaaaat
     9901 atggctcaaa attactatga cgaatttgtc aaattacctt tggataaaat ggcacaaaaa
     9961 atggaggata tgacattcct ataccatgag acacgtgttc caaaaaaaca ttataaggaa
    10021 agattgtcgg tagctgtgga agaaatgatt gaatcaggtg tcgaaatgaa tctcattgcg
    10081 acgtactatc gaacactgga agaactgaaa aaacaaaatg caaaatggtt tttccaagcc
    10141 ttactatgct tggaagtagg tgtcaaacca agcactatta aaccttctga atatcaagct
    10201 ttagaactaa cgtatgggaa atttgtcgaa acgaaaaaag ccaagactgt ttcaagtgaa
    10261 tggttagatt attttgaaaa tatcaataag tatggcgcct attacaccat gaaaaaggag
    10321 gacaacgaaa atgaataagg tgatttatca actaacaacg gaagatgtgt cacacttttt
    10381 aacaaacaaa gaacatttga atgaagtaat cagacggatt caaaaagact ttagttgtat
    10441 ggaagaaatg aagtacttta ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac
    10501 gagtcaaacg aaggtcacag tcagcaataa ttatttagac gtgtataaac atcgtcctga
    10561 aacggtaaaa aaaggaacgg agcttctacg actagaaaca gaaaaataca tcatgaatgt
    10621 ttacctagaa aggagtgaac tggtcgaaaa ctttgtcagc tgcacgattt gcaggaaaca
    10681 ctattactca gaatcagaat attattcaat ttttgagagc atggaattaa tggaagaaga
    10741 aatggaagag ctaaacagca aaaatgcgac gatagacgat tattatcttg tatttactag
    10801 atttttgacg tgtggaacgg aatctatcgt gttaatggga atggattatg aactcgctgt
    10861 acccgaagca tttttgaggg aatatgtaga agaagtagat aacccaggcg acgactggta
    10921 cacgacttta actgattttt tagataccta cacttacgac gatacagaag aaatccaaaa
    10981 tgaacttgac cgtaaacgaa tgccatatca acgatttgaa aggaaaaaaa ggcaataatc
    11041 atttataccg aaaagtgaga atgtgtgaaa taagaacaaa aaccttgaaa ttaagggaat
    11101 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataag
    11161 cgggcaaagc ccgataacct aagagaaaga aggagatcca tatgaataaa atcattcctc
    11221 tgttgttcgt actgtgtatt ggcgagatac ttatgcgtca tggtgcagct gtacatttaa
    11281 acttcgtagt attcttagga atactagtat tttgtttgat tttttggcgc tttgtgttag
    11341 cccttgtgag tctactattc aagttgattg cagccatatt tttcataggg ttatttcgat
    11401 gaaaggagag agtactaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
    11461 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtacggaaaa agtgaatcta
    11521 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatatac
    11581 cagcactaaa aaagtgacgt cacttttcat ttgaagaaac aaaagtgata gcacttaatt
    11641 gttcctacta tttagaatat tttctatgtc ctttttattc cattttgtat caataactat
    11701 gaaatcttta aagtatccag atcaattttt ttcttacctg attctaaaga ttttgttttc
    11761 ttaaacatat tatgatttcc tttcgactat tttcatataa atgttaacat agtttatgga
    11821 ttcatggaat gttaatctaa tttaatagaa aaggataatt aagtatatac gttttttctt
    11881 atgtatgtta tactatgtat atacagaaag aggtgtctac tatggaaatg ttacctataa
    11941 aaaaatgggg aaatagtaat ggccttagat tgccaaagta tattatggaa tatcttggaa
    12001 ttcatacaga agacaaagtg aagataatac aagaagaagt aaacggtcag aagcggctaa
    12061 ttatcgaagc ggctaatata gaaaatgaat taacaattga acagttattt gaaaattaca
    12121 ctgatgaaag aaatcatgtg acgattcaaa atttaggtga agcagtaggt aatgaaaaat
    12181 ggtgagaaaa cctagacaag gcgatattct attattgaat acagcacctc gatctggaca
    12241 cgaacagaca ggtaaaagac cttatattgt tttaagtcat gatattattg cggattatag
    12301 taacgttgtt acagttgctc caatttctag tacaactaga aactatccgc tatatgtaaa
    12361 tataaactca gaatatgaaa tgaagacaac aggaaaagta ttattagatc aactaacgac
    12421 aattgattat gaagccagag agtgtatttt tttggaaaaa gcgcatgata gtttagttga
    12481 ggagttattg atgaaagtta gaacagtttt tcaaaaagta agcaaataaa atagaaacag
    12541 cagcatgatc aactattcgt gattgaccat gctgtctttt tttattctat atacggtttg
    12601 tctcgtaaca ttgtagtctt ttgcaatctt agcgatcgca acaccttttt ttagatcctc
    12661 aacgatgttt ttataaacaa gacgacgttg gggatctttt gcattggcac tgtatagctt
    12721 aggacgtcct ttataaacac cgttcgcttt tgcaatctta atgccttgtg cctgacgtcg
    12781 tttagattcg gtacgttctt gttcagcgat catggccaaa atttgaatga tcaaatcttt
    12841 aatgaattta tccaggagag gattgccaat tgcttcggcc atgatcggta gacttgtgat
    12901 gatcagctgc acatttttct tcttcaagta attgactgaa gcgatgatct cgtcgtaatt
    12961 tcttccaagt cgatcaatag cttccacaat aaaaatatct tgatctcgga cgaaatccag
    13021 tgcttcttga aaaacaggtc gatgagtaat cgttgcgcca gattgtttct caatgaaaat
    13081 tctctctgca ccgaattttt tcatttcttc aatctgccgt tgttcatttt gatcgatgga
    13141 tgagacacgt atgtatgcaa ctctcaaaat ttttacctac tttctgcaac tatttaaaaa
    13201 acaccctaat catacacgag aaaaccagat ttttcaatgt cgcggtcgtg tctagttagg
    13261 gtatacctta tatagacaaa aactaatgat ggaggaaata gtatgtgtca cttttctttt
    13321 taaatggcaa tattttttgt aaataaatgt caatcaagaa aatttaaacg attatgacat
    13381 taaaaatata ttttatgaat tttctagtat ataacttgat ttatctgtta agatttatta
    13441 agaaaacgtt ttcttatttt tgatttcgag gtgatagaca atgaaaaata agtttatttt
    13501 atctttaggt attttaacta ttggaattag tgtaactgga actacaattc ctacatttgc
    13561 tgatagtaca aatgaaccaa ctactgtagt agataataac caagaattaa ctcctttaga
    13621 taggaacgga atagccattg gtaacccaac taacgactta actgttactg aaaattattt
    13681 aatagtttct ccattacttg ctcgagcagc ttctaaaacg atacgagtga caggaacgat
    13741 gatttttgat aaagttggtt ggccttctag acctcctcaa tcacggaatt ggaaagaaaa
    13801 aagaaatggt tattggtact atggaaaatt gtatttacaa agttataaat cagctggaaa
    13861 caattggatt gcgacttatt caggaacctt aactagaaag tagggatttt ttatgccaga
    13921 atttgtgaac acaccaaatt tttatcaaga tagcgatatt ctaagtaaaa ttaatttacc
    13981 gaaagaagaa tcagctttac aagttcagcg aactttacag gagacacaaa aaattcaaaa
    14041 atcaatttct aatctagaag attctgaaga aaaaagaaaa aaaagagacc aaaaaacata
    14101 tcaaaaagaa aaataatgat tttaaaaaaa gagtgtctag tcgacattct ttttttctaa
    14161 ttgaaagtgt tcataaaatc acccatttct ggacactttc tttttttgct ttatttttca
    14221 aaaaaacaat tcatttcatg ttcataaacc cataacaata tctatgttca gttaaactat
    14281 atggataaag ttatgttaca ataaaattaa tgaaggagtg atttttttga aaataggata
    14341 cgcccgggta tctactggtt tacaaaattt ggatttacaa gaagacagcc taaataaatt
    14401 tggttgtgaa aaaattttta ctgatcatat gagtggggca aaaagtaatc gaccaggatt
    14461 agaaatggcc attgattttg ttcgctctgg cgatacactt gtcgtttggc gcttagatcg
    14521 tttaggtaga aatatggaag atttgatttc aatcgtcaat cgactgaatg agcgtggtgt
    14581 gagttttcat agtattcaag aaaatattac gatggacaaa tcaagttcta caggacagct
    14641 catgtttcat ttgtttgcgg catttgcaga atttgagcgt aatttgatcc tggaacgatc
    14701 cgcagcagga cgagcagctg ctcgtgcaag aggacggttt ggtggtcgtc ctgaaaaatt
    14761 gtctgaacaa gatttggaat tactgaagac tttagtggat agcggtacac ctattaagac
    14821 tattgcggaa cggtggaacg tctcaagaac caccatttat cgttatttgg caaaaatgga
    14881 ggagaaaaat ggaaagacaa attctcatta gtttttgtca tttaatgctg aaaatttttg
    14941 ccatttatct agaaaagtga caatagtatg agaatttttt gtaagtgtct actgataact
    15001 tattctcaaa tgttgtaagg attttattca tttgttaata ttaaagaacg gaactccaaa
    15061 aaagtccgta ctctaatttg cagtctctca ctcttttaga gtgagagttt ttattagatt
    15121 ttcaaattaa ttagtaaag
//
LOCUS       DAYYEF010000062        14187 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000062 DAYYEF010000000
VERSION     DAYYEF010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14187
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.065"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..481
                     /locus_tag="ACHA1B_002286"
     CDS             <1..481
                     /locus_tag="ACHA1B_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HFM8703029.1"
                     /translation="GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETA
                     LNQWFSRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGI
                     LRRNGLPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            803..973
                     /locus_tag="ACHA1B_002287"
     CDS             803..973
                     /locus_tag="ACHA1B_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703030.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            987..1589
                     /locus_tag="ACHA1B_002288"
     CDS             987..1589
                     /locus_tag="ACHA1B_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703031.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1605..2282
                     /locus_tag="ACHA1B_002289"
                     /pseudo
     CDS             1605..2282
                     /locus_tag="ACHA1B_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2593..3090
                     /locus_tag="ACHA1B_002290"
     CDS             2593..3090
                     /locus_tag="ACHA1B_002290"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HFM8703032.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDR
                     ERMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTN
                     SASGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLK
                     EKVVR"
     gene            3091..3507
                     /locus_tag="ACHA1B_002291"
     CDS             3091..3507
                     /locus_tag="ACHA1B_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HFM8703033.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3527..5071
                     /locus_tag="ACHA1B_002292"
     CDS             3527..5071
                     /locus_tag="ACHA1B_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703034.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            5214..5438
                     /locus_tag="ACHA1B_002293"
     CDS             5214..5438
                     /locus_tag="ACHA1B_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703035.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            5453..6322
                     /locus_tag="ACHA1B_002294"
     CDS             5453..6322
                     /locus_tag="ACHA1B_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFM8703036.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            6303..7037
                     /locus_tag="ACHA1B_002295"
     CDS             6303..7037
                     /locus_tag="ACHA1B_002295"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM8703037.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            7070..7978
                     /locus_tag="ACHA1B_002296"
     CDS             7070..7978
                     /locus_tag="ACHA1B_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFM8703038.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7975..8517
                     /gene="sat4"
                     /locus_tag="ACHA1B_002297"
     CDS             7975..8517
                     /gene="sat4"
                     /locus_tag="ACHA1B_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFM8703039.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            8610..9404
                     /locus_tag="ACHA1B_002298"
                     /note="aph(3')-IIIa"
     CDS             8610..9404
                     /locus_tag="ACHA1B_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFM8703040.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            9680..9811
                     /locus_tag="ACHA1B_002299"
                     /pseudo
     CDS             9680..9811
                     /locus_tag="ACHA1B_002299"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            9887..10380
                     /locus_tag="ACHA1B_002300"
                     /pseudo
     CDS             9887..10380
                     /locus_tag="ACHA1B_002300"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            10550..11446
                     /locus_tag="ACHA1B_002301"
     CDS             10550..11446
                     /locus_tag="ACHA1B_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM8703041.1"
                     /translation="MIQYYYTKKEWGVVMEKEKLKILEELRRILNNKNEAIIILNNYF
                     KGGVGKSKLSTMFAYLTDKLNLKVLMIDKDLQATLTKDLAKTFEVELPRVNFYEGLKN
                     GNLASSIIHLTDNLDLIPGTFDLMLLPKLTRSWTFENESRLLATLLAPLKSDYDLIII
                     DTVPTPSVYTNNAIVASDYVMIPLQAEEESTNNIQNYISYLIDLQEQFNPGLDMIGFV
                     PYLVDTDSATIKSNLEELYKEHKEDNLVFRNIIKRSNKVSTWSKNGITEHKGYDKKVL
                     SMYENVFFEMIERIIQLENEKE"
     gene            11545..11754
                     /locus_tag="ACHA1B_002302"
     CDS             11545..11754
                     /locus_tag="ACHA1B_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFM8703042.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            11771..12043
                     /locus_tag="ACHA1B_002303"
     CDS             11771..12043
                     /locus_tag="ACHA1B_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFM8703043.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            12045..12908
                     /locus_tag="ACHA1B_002304"
     CDS             12045..12908
                     /locus_tag="ACHA1B_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFM8703044.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(13171..13908)
                     /gene="erm(B)"
                     /locus_tag="ACHA1B_002305"
     CDS             complement(13171..13908)
                     /gene="erm(B)"
                     /locus_tag="ACHA1B_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFM8703045.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(14033..14116)
                     /locus_tag="ACHA1B_002306"
     CDS             complement(14033..14116)
                     /locus_tag="ACHA1B_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFM8703046.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
BASE COUNT         5018 a         2222 c         2928 g         4019 t
ORIGIN      
        1 tggtcacctt gaaggtgata cgatcgttgg cattcatcat aaaagtgccg tcattacttt
       61 agttgaaaga ttatctaaag tcattatcac gattaaaccc aacggccgta aggcattaga
      121 tattgaaact gcccttaatc aatggttttc tcgcttccct aaaaacttct ttaaatctat
      181 tacgtttgac tgtggaaaag aattttctaa ctggaaagcc attagtaacc aacatgatat
      241 tgatatatat tttgcggacc ctggaacacc ttctcaacgc ccattaaacg agaattctaa
      301 cgggattctg cgtcgtaatg gactgccgaa atcaatggat tttagaaaag tgaatcagac
      361 atttatttcc agtgtcagca atcaacgtaa tcatattcca agaaaatcat tgaattacag
      421 aacaccaatc gaaatatttt tgagctatgt acaagaagca ttttattcta gcttaatttg
      481 acaaatcata ctatgatacg tgtttgtttt tctgtgctgt ttagtgaatg attagcagaa
      541 atatagagag taagatttta attaattatt agggggagaa ggagagagta gcccgaaaac
      601 ttttagttgg cttggactga acgaagtgag ggaaaggcta ctaaaacgtc gaggggcagt
      661 gagagcgaag cgaacacttg atcttttaag ttgctatctt tttaaggtca atagagtata
      721 cttatttgtc ctaatatggt tttagcagta taattgactt ggtgaatagg tcatttaagt
      781 tgggcataat aggaggagta aaatgaaaaa atttatttat cgagttttag aaaatgacga
      841 agtggtggct atttttaatg agcaacaata tgcgcaagat tttatcgctt acgaaaagac
      901 aatttctgat aagcaatttg aaattgaaaa agtagatata gctgattggt tattgcaacc
      961 gagagaattt tagaggttgg ttgaaaatgg ctaaaattgg ttatgcacgt gtcagtagca
     1021 aagaacagaa cttagataga caactgaaag cgttagaggg cgtttctaag gtcttttcag
     1081 acaaattaag cggtcaatcg gtcgaacgcc cacaattaca agctatgctt aactatattc
     1141 gtgaagggga tatagttgtt gttactgaat tagatcgatt aggacgaaat aataaagaat
     1201 taacagaatt gatgaatcaa attcaaatta agggggcaac cctggaagtc ttaaatttac
     1261 cctcaatgaa tggtattgaa gatgaaaatt taagacggct gattaataat ttagtgattg
     1321 aattgtataa gtaccaagcg gaatctgaac gcaaacgaat taaagaacgc caagcccaag
     1381 gaattgaaat tgctaagaaa aaaggaaaat tcaaagggcg acaacctaaa ttcaaagaaa
     1441 atgatccacg tttacaacac gctttcgatt tatttttgaa tggttgttcc gataaagaag
     1501 ttgaagaaca aactggaatt aatcgccgaa cgtttagaag gtatcgatca agatacaacg
     1561 tgacagtaga tcaaagaaaa aaacaatgaa aagagggata gttaatgagt acggttattt
     1621 tagctgaaaa accaagccag gcattagcct acgcaagtgc tttaaaacaa agcaccaaaa
     1681 aagacggtta ttttgagatc aaagacccac tatttacaga tgaaacgttt atcacctttg
     1741 gttttgggca tttagtcgaa ttagcagaac caggtcatta taacgaaaag tggcagaact
     1801 ggaaacttga atctttgccg atttttcctg atcgatacga ttttgaagtt gcaaaagata
     1861 agggaaagca gtttaaaatt gttgctgaac ttctcaaaaa ggcaaataca attattgtcg
     1921 caacagatag cgacagagaa ggtgaaaata tcgcctggtc gattatccat aaagcaaatg
     1981 ccttttctaa agataaaacg tataaaagat tatggatcaa tagcttagaa aaagatgtga
     2041 tccgaagcgg ttttcaaaat ttgcaaccag gaatgaatta ctatcccttt tatcaagaag
     2101 cgcaaacacg ccaaattgcc gattggttga tcggcatgaa cgcaagccct ttatatacct
     2161 tgaatttaca acaaaaaggc gtacaaggta cattttcatt aggacgtgta caaacaccga
     2221 ctttatatct catttatcaa cgccaggaag caatagaaaa ctttaaaaaa gaaccttttt
     2281 tcctgaataa ttcatagttt tactaatagt ctttcctaac attgatttaa tagtctttaa
     2341 agtattctgc ttcatcaccc attaggtgat gaaaaaagaa cccctttctg atttagcgga
     2401 caaatacttt gacctaatct cagaagatat aaaagaaaaa ataataaaat atccgattta
     2461 tactttgtat aaagaactaa agtagttagc aaatcattta cagcaaatca ctatgttcca
     2521 cataccattt tacatactta ccttatccac gacacatgtt gagatagtat cgaagataaa
     2581 gaaagttgct ccatgttgtt tttgcgagat ggggaaatca aagccacatt gacaaccatg
     2641 atgaataagc ttgctttcag tcataagcta atcctagaac cacttttcaa gtcagttagc
     2701 caaatcgatg aagaaagcga ccgtgaaaga atggacgcta ttgataagct aatggagcaa
     2761 ctattggaag aacgcaatac ccttattgca ctgatgtcca aaggtttcct agaacctgct
     2821 ctttttaatc aggaacgaaa tgttttagat agtgagatta aaaatcttac taccgaaaaa
     2881 acaaacctgg taacgaactc tgcgagtggg gttttgcgag caaacgagat aaaggacctc
     2941 attaattatg tgtcagcaga taattttaat ggtgactaca cggaagaact atttgaagaa
     3001 tttgtagtga acatcattgt aaattccagg gatgagctga cattcaattt gaaatgcggt
     3061 ctttccctga aagaaaaggt ggtgagataa atggcatata ttccatatgg atacaaaatt
     3121 caagatggag tggttactgt cgatgaaaag gcagcaggtc aagtaaaggt attctttgag
     3181 aaatacatat caggactatc ccttacagtg gctggcgaac aggcaggtat tgaaaagaca
     3241 cattctgtga tggggcgcat tttgaaaaac gtcaactacc ttggaaatga tacgtatcca
     3301 gcaattattg ataaagagat atttgataaa gctgaagaag ttagagataa acgtgcaaag
     3361 gatttaggac gagtggtaga gcttgccgct ttcacctctc cccctcccaa agaacgattc
     3421 aaaatgaaaa aggcagataa taagatgcca gtggatcctt ttgaacgagc agaatactta
     3481 tacagtctga tagaaagcga ggaataaagt gacagagaaa aatataatgg ttattcctgc
     3541 tcgtaaaaga gtaggaagta cagccgcaaa agaaaagata aagaaacttc gtgttgctgc
     3601 ctattgccgt gtttctacag aaacagaaga acaaaattct agctatgagg ttcaggtctc
     3661 acactataca gagtttataa agaaaaataa tgaatgggag tttgctggca tctttgcaga
     3721 tgatggtatc tctggtacga acactaaaaa gcgtgacgaa tttaatcgca tgattgcaga
     3781 gtgtatggac ggtaacatcg acatggttat tacaaaatcc atcagccgat ttgcgcgtaa
     3841 caccctagac tgccttcaat acattagaca gctcaaggat aagaacatat cagtttattt
     3901 tgagaaagag aacatcaaca ccacggatgc caaaggtgag gttttgctga ctattatggc
     3961 atctttggca cagcaggaaa gccagagcct ttcacaaaac gttaagcttg ggctacagta
     4021 ccgataccaa caaggaaagg tgcaggtcaa ccataagcga tttatgggct acacgaaaga
     4081 tgaagatgga aatttaacta ttgtccccga agaagctgag attatcaaac gcatctaccg
     4141 agaatacctt gagggtcaga gtctagtggg cattggtcga gcccttgaaa aggatggtat
     4201 tttaacagca gcgggaaaac caagatggcg accagaatca gttaagaaga tacttcaaaa
     4261 cgaaaaatac atcggagatg cccttctgca aaagactgtc acagtagatt ttctgaccaa
     4321 gaaacgagtg aaaaatgaag ggcatgttcc ccaatattat gttgaaaata gccatgaagc
     4381 gattattcct aaagagttat ttttgcaggc gcaagaagaa attcatcgga gaagcaatat
     4441 ctacacagga gaaggcaaga acaaaagaat ttacagtagc aagtacgctt taagtgccat
     4501 caccttctgt ggagattgtg gcgatattta tagacgggtc tattggaata tccacggaag
     4561 aaaagaattt gtctggcgat gcgtgactag aatcgagcaa ggtcctgaag tttgtaagaa
     4621 ccgaaccgta aaagaagatg aactttatgg tgcagtaatg actgcgatta ataagctact
     4681 tgcaggtggg aacaatatga taaagacact ggaagagaat attcatgctg tgattggcga
     4741 aaccacagaa taccaaattt cagagattaa caactcacta gaggaaaaac aaaaagaact
     4801 aatcaagctg gcgaacaagg gtcaagacta tgaccactta gcagatgaga ttgatgagct
     4861 gagagacaag cgacagatcc ttttagtaga agatgcctcc ctcagtggcg agaacgagcg
     4921 aatcaatgag ctgattgaat ttatccgcaa gaacaaattc cgcaccttag aatatgatga
     4981 taagcttgta aggaagataa tccagagcgt tacagtctat gaaggccact tcgtcatagc
     5041 cttcaaatct ggcatcgaaa tggaaatatg aaaaccagaa gtaaatagcc catgactcta
     5101 cagtagagtt gtgggttttc ttttgcttgc tgattataat aatattttaa taactattgt
     5161 gtttatcaac caaatggttt ataatattct tagcgtaaac ttggaggtgc tgtatgacta
     5221 cggcagaaat gattaaagaa ctgtgtgagc aaatgaatat aagtgtttcc gaacttgcta
     5281 gacgtattgg ccagactcca cagaatttca ataaaaaatt acaacgagaa acagtaacct
     5341 tggatgagtt gaaggccatt gctgatgtgc taggtgtcaa gtttgtgcag gcatttattt
     5401 taccagatgg agaagaaata aaaatatcta acgaataaag gaggatgttt atatggtagg
     5461 taatgttatt caaatagtaa cagagaaatt atcatctttg ccttttatag aaggcatcgt
     5521 attagggggc tcacgtgcaa gaggcaccca tacagaaaat tctgatatag atatcggaat
     5581 ctattacaat tcagactcat ttgacctgac agcgattaat caaattgcta cagagttgga
     5641 tgatgagaat agaaacaacc ttgttgtacc tcccggagcg tggggtgatt gggttaatgg
     5701 cggtggatgg ttagttataa acgggtgtca tgttgacttg atattacgtg atataaaacg
     5761 ggtggaacaa ataatcaaag atacggagca aggaattgtt actgccaatt atcagaccgg
     5821 gcatccccat ggttatataa gtgctatgta tcgtggagaa ttagcgatta gtaaaatact
     5881 atatgctaag aacgaaagct tatgcgaatt aaaaaagcag gcagaaattt accctactgc
     5941 tctaaagaaa agcttgatga acttttttat atttgaagct gaattctctt taatgtttgt
     6001 aaaagcaaat gcgggggcag aggataaata ttatattgca ggccatgttt ttcgtattat
     6061 ttcatgctta aatcaagtac tatttgcatg taataatgct tattgcatta acgaaaagaa
     6121 agctataaaa ctgcttgaaa cttttgaata taaacctgaa aaatatgccg aaagagttaa
     6181 tcatattttt gaagtactcg gtctttctct ttttgaatgc tacgacatga ccgagaaact
     6241 ttataaagaa gtgaatgaaa ttgtatcgga gataaataac tttttaaacg aggagagttc
     6301 agatgaaaga aaacaaatat gatgataata tattttttca aaaatacagt caaatgagtc
     6361 gctcgcagaa aggactggct ggtgcgggag aatgggagac tttgaaaaag atgctacctg
     6421 attttaaggg taagcgtgtg cttgatttag gatgcggcta tggatggcac tgtatatatg
     6481 cgatggaaaa cggtgcttcc tctgtagtag gtgttgatat ttctcataaa atgctcgaag
     6541 tagcaaaagg aaaaacccat tttccacaga ttgaatatga atgctgtgcc atagaagatg
     6601 tggatttccc agaggagagc tttgatgtaa tactaagttc gcttgcgttt cattatgtag
     6661 cagactatga gaatttaata aaaaagatat ataggatgct gaaggctggt ggcaatttag
     6721 tttttacagt tgaacatcct gtttttactg ctcatggaac acaagactgg tattataacg
     6781 aaaaaggaga aatactgcat ttcccggtgg acaattatta ttatgagggc aaacggacag
     6841 ctatgttttt ggaagaaaag gttacaaaat atcatagaac actgaccaca tatctaaata
     6901 cactgctttc aaatagtttt ataataaatc agattgtgga gccacagccg ccagagaaca
     6961 tgatggatat tccggggatg gcggatgaaa tgcgacgccc aatgatgctg attgtatcgg
     7021 caaaaaagaa gatgtaataa tatagaaaaa ataaacgagg agtatgtaaa tgagatcaga
     7081 aaaagaaatg atggatttag tactttcttt agcagaacag gatgaacgta ttcgaattgt
     7141 gacccttgag gggtcacgcg caaatattaa tatacctaaa gatgaatttc aggattatga
     7201 tattacatat tttgtaagtg atatagaacc gtttatatct aatgatgact ggcttaatca
     7261 atttgggaat ataataatga tgcaaaagcc ggaggatatg gaattattcc cacctgaaga
     7321 aaagggattt tcctatctta tgctatttga tgattacaat aaaattgatc ttaccttatt
     7381 gcccttggaa gagttagata attacctaaa gggcgataaa ttaataaagg ttctaattga
     7441 taaagattgt agaattaaaa gggacatagt tccgactgat atagattatc atgtaagaaa
     7501 gccaagcgca agggagtatg atgattgctg caatgaattt tggaatgtaa caccttatgt
     7561 tattaaagga ttgtgccgta aggaaatttt atttgctatt gatcatttta atcagattgt
     7621 tcgccatgag ctgctgagaa tgatatcatg gaaggtcggc atcgaaacag gctttaaatt
     7681 aagtgtaggc aagaactata agtttattga aaggtatata tccgaggatt tgtgggagaa
     7741 acttttgtcc acctaccgga tggattccta tgaaaacata tgggaagcat tatttctatg
     7801 ccatcaattg ttcagggcgg tatccggtga ggtggcggaa aggcttcatt atgcctatcc
     7861 ggagtatgat aggaatataa caaaatatac cagggacatg tataaaaaat acactggtaa
     7921 aaccggctgc ctggatagca catatgccgc tgatatagaa gagaggcggg aacagtgatt
     7981 acagaaatga aagcagggca cctgaaagat atcgataaac ccagcgaacc atttgaggtg
     8041 ataggtaaga ttataccgag gtatgaaaac gagaattgga cctttacaga attactctat
     8101 gaagcgccat atttaaaaag ctaccaagac gaagaggatg aagaggatga ggaggcagat
     8161 tgccttgaat atattgacaa tactgataag ataatatatc tttactacca agacgataaa
     8221 tgcgtcggaa aagttaaact gcgaaaaaat tggaaccggt acgcttatat agaagatatc
     8281 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
     8341 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
     8401 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
     8461 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
     8521 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
     8581 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
     8641 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
     8701 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
     8761 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
     8821 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
     8881 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
     8941 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
     9001 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
     9061 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
     9121 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
     9181 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     9241 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     9301 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     9361 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     9421 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     9481 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag agttctatat
     9541 tagagatgta aagagttttg gtgaagaggt ttgtgagtat ggcttttata accagggtgc
     9601 aatgagaagc actaacagca gctagcttaa gaacgcatag gatatacttt ttatggaagt
     9661 cacagaggag gaataaaatt tgaacaggat taacagagta acctctattc ttattcagct
     9721 gcaatcaaaa aaaataattc ctgccaaaga aattgcacag cgatttaata taagcttaag
     9781 gacagtttac agagatatcc ggacacttga agaagccgga ataccaattg gatctgaggc
     9841 cggaaaagga tattttcttg tagagggctt cctacttccg ccggtaatgt ttacagcggc
     9901 ggaagtgggt gcattgatta cagcagggaa atttttaaat tgccatggag atgaatcatt
     9961 tataaaggat tttgattcag ctatgtataa aatcaaatct attttgaagc atggtgaaaa
    10021 aaactatgca caggagttgg agaacagtat taacgtgtac agcacatctg gacagaaaaa
    10081 tacattggcg gataacgtta ttgcagcaat tcagactgca atctgcaata aaagggtaat
    10141 atcaattcaa tatcctgcat caggagggca agaaccggaa agcagaatga tagagcctat
    10201 atcactgggg ttttatgaac agaactggta cttaatcggt tttgcaggct aagaaatgaa
    10261 tataggaatt ttcgtgtgga tcggattaaa agcatttgca tagaagaaga gctctgtcaa
    10321 agccatgatg gctctttgga acaaatatta aaacaaatgc tttcatataa aaaactatat
    10381 gccctacaat gccgttgtaa aaattgggga aaagggatat attgatttta tatctttctc
    10441 aaaataaata taaaagccct ttaaagaggg cttttatata ttaatcacaa atcacttatc
    10501 acaaatcaca agtgattaat cacaaatcac ttgtgatttg tgattcttaa tgatacaata
    10561 ttactataca aaaaaagaat ggggcgtagt tatggagaag gaaaaactaa aaatacttga
    10621 agaattaaga cgtattttaa acaataaaaa tgaagcaatt attatcttga ataattactt
    10681 taaaggtggt gttggaaagt ccaaattatc gactatgttt gcttacttga cagacaaatt
    10741 gaatttaaaa gttttaatga tcgataagga cttacaggca acattgacaa aagacttagc
    10801 aaaaactttt gaggtagaat tgccacgtgt caatttttat gaaggcttga aaaatggaaa
    10861 cttggcttct tctattattc atttgactga taatttagac ttgatccctg gcacgtttga
    10921 tttgatgtta ctgccaaaat taactcgctc atggacgttt gaaaatgaaa gtagattgct
    10981 tgctactctt ttagcacctt taaaaagtga ctatgatctt attattattg atactgtacc
    11041 aacgccaagc gtttatacaa ataatgcaat cgtggcgagt gattacgtta tgatcccttt
    11101 acaagcagaa gaagaaagta caaacaacat tcaaaactat atttcctatt tgattgattt
    11161 gcaagaacag tttaaccctg gactagatat gattggtttt gttccttatt tagttgatac
    11221 ggacagcgca acgataaaat caaacctgga agaactgtac aaagaacata aagaggataa
    11281 tttggttttc cgaaatatta tcaagcgaag taataaagta agtacttggt ctaaaaatgg
    11341 cattacagaa cacaaaggct atgacaaaaa agttttgtct atgtatgaga acgtattttt
    11401 tgaaatgatt gagcgaatca ttcaattaga aaatgaaaaa gaatagaatc acaaatcaca
    11461 agtgattaat cacaaatcac ttgtgatttg tgataggtga tgataaaata aatagtaaga
    11521 agaaatagaa agaagtgagc gatcgtggga aatttaggcg cacagaaagc aaaacgaaat
    11581 gatacgccaa tcagcgcaaa aaaagatata atgggggata agacggttcg tgttcgtgcc
    11641 gacttgcacc atatcataaa aatcgaaaca gcaaagaatg gcggaaacgt aaaagaagtt
    11701 atggatcaag ccttagaaga atatatacgg aaatatttac ctgacaaact ttaaaaggag
    11761 tgaaaatgaa atggcagtta cgtatgaaaa aacatttgaa attgaaatca ttaatgagtt
    11821 atcggcaagt gtttataatc gggtattaaa ttatgttttg aatcatgaac tagatactaa
    11881 aaatactcgt ttactagaag tgaatctttt aaatcaatta gaagtggcac aagaagttga
    11941 tttatttcaa caaccatttg aagaattaca agctattcat gagtattggc ggtcaatgaa
    12001 tcaatattca aaacaaattt tgaataaaga gaaagtggct taacatggcg aatattactg
    12061 acttcaccga aaagcaattt gaagatcgtt tagaaaagaa tgttgaacga ctaactaaaa
    12121 atagactagc ggttgaatcg ccaaccgctt ttttacttgg tgggcaacca gggtcaggga
    12181 aaaccagttt gcgatcagca atttttgaag aaacacaagg gaatgttatt gtcattgata
    12241 atgatacctt taaacaacag cacccaaatt ttgacgaatt agtgaaactc tatgaaaaag
    12301 acgtagtaaa acacgttacc ccttattcga atcgcatgac agaagcactt attagccgtt
    12361 taagcgatca aggctataat ttagtgattg aaggaacagg acgaacaaca gacgttccca
    12421 ttcaaacagc cacaatgctt caatctaaag gttatgaaac aaaaatatac gtcatggcag
    12481 taccgaaaat tgaatcatac ttaggaacga ttgaacgata tgaaaccatg tatgcagatg
    12541 atccaatgac agctagggca acaccaaaac aagcgcatga tattgttgtc aaaaacttac
    12601 cgaccaattt agaaaccctt cataaaacgg gcttatttag cgatataagg ctttacaata
    12661 gagaaggagt gaaactctat tcaagcttag aaacgccttc cattagtccg aaagagacct
    12721 tagaaagaga attaaatcgt aaagtatcag ggaaagaaat tcaaccgact ttggagagaa
    12781 tagagcaaaa aatggttcaa aatcaacacc aagaaacccc tgaatttaaa gcaattcaac
    12841 aaaaaatgga aagcttgcag ctacctacac caccaatacc caaaacacct aaacttccag
    12901 gtatttaaac cttaaaaaag gaaaagagta gttaccaaaa aacggtaact actctttttt
    12961 tataaaaaca tttcctcatg ttggggtccc gagcgcctac gaggaatttg tatcgataag
    13021 aaatagattt aaaaatttcg ctgttttttt ctaatttcat tttgaggtga attaattggt
    13081 agttattaga ggtgccctat acctaataat ttatctacat tccctttagt aacgtgtaac
    13141 tttccaaatt tacaaaagcg actcatagaa ttatttcctc ccgttaaata atagataact
    13201 attaaaaata gacaatactt gctcataagt aacggtactt aaattgttta ctttggcgtg
    13261 tttcattgct tgatgaaact gatttttagt aaacagttga cgatattctc gattgaccca
    13321 ttttgaaaca aagtacgtat atagcttcca atatttatct ggaacatctg tggtatggcg
    13381 ggtaagtttt attaagacac tgtttacttt tggtttagga tgaaagcatt ccgctggcag
    13441 cttaagcaat tgctgaatcg agacttgagt gtgcaagagc aaccctagtg ttcggtgaat
    13501 atccaaggta cgcttgtaga atccttcttc aacaatcaga tagatgtcag acgcatggct
    13561 ttcaaaaacc acttttttaa taatttgtgt gcttaaatgg taaggaatat tcccaacaat
    13621 tttatacctc tgtttgttag ggaattgaaa ctgtagaata tcttggtgaa ttaaagtgac
    13681 acgagtgttc agttttaatt tttctgacga taagttgaat agatgactgt ctaattcaat
    13741 agacgttacc tgtttactta ttttagccag tttcgtcgtt aaatgccctt tacctgttcc
    13801 aatttcgtaa acggtatcgg tttcttttaa attcaattgt tttattattt ggttgagtac
    13861 tttttcactc gttaaaaagt tttgagaata ttttatattt ttgttcatgt aatcactcct
    13921 gaagtgatta catctataaa taaatacaga agttaaacga tttgtttgta attttagtta
    13981 tctgtttaaa aagtcataag attagtcact ggtaggaatt aatctaacgt atttatttat
    14041 ctgcgtaatc actgttttta gtctgtttca aaacggtaga tgttttatct acattacgca
    14101 tttggaatac caacatgacg aatccctcct tcttaattac aaatttttag catctaattt
    14161 aacttcaatt cctattatac aaaattt
//
LOCUS       DAYYEF010000063        13872 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000063 DAYYEF010000000
VERSION     DAYYEF010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.066"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(83..1891)
                     /gene="uidA"
                     /locus_tag="ACHA1B_002307"
     CDS             complement(83..1891)
                     /gene="uidA"
                     /locus_tag="ACHA1B_002307"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HFM8703047.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(1914..3680)
                     /locus_tag="ACHA1B_002308"
     CDS             complement(1914..3680)
                     /locus_tag="ACHA1B_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="HFM8703048.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(3693..4487)
                     /locus_tag="ACHA1B_002309"
     CDS             complement(3693..4487)
                     /locus_tag="ACHA1B_002309"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM8703049.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(4497..5873)
                     /locus_tag="ACHA1B_002310"
     CDS             complement(4497..5873)
                     /locus_tag="ACHA1B_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM8703050.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(5993..6640)
                     /locus_tag="ACHA1B_002311"
     CDS             complement(5993..6640)
                     /locus_tag="ACHA1B_002311"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HFM8703051.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(6724..8151)
                     /gene="uxaC"
                     /locus_tag="ACHA1B_002312"
     CDS             complement(6724..8151)
                     /gene="uxaC"
                     /locus_tag="ACHA1B_002312"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HFM8703052.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(8225..9304)
                     /gene="uxuA"
                     /locus_tag="ACHA1B_002313"
     CDS             complement(8225..9304)
                     /gene="uxuA"
                     /locus_tag="ACHA1B_002313"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFM8703053.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(9307..10938)
                     /locus_tag="ACHA1B_002314"
     CDS             complement(9307..10938)
                     /locus_tag="ACHA1B_002314"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HFM8703054.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            11242..11913
                     /locus_tag="ACHA1B_002315"
     CDS             11242..11913
                     /locus_tag="ACHA1B_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM8703055.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
     gene            complement(12073..12264)
                     /locus_tag="ACHA1B_002316"
                     /pseudo
     CDS             complement(12073..12264)
                     /locus_tag="ACHA1B_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
     gene            complement(12632..12973)
                     /locus_tag="ACHA1B_002317"
     CDS             complement(12632..12973)
                     /locus_tag="ACHA1B_002317"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703056.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIGSGISSVRLKEKEYTQKIIHIPKPEIKRFEIKDY
                     SALGLFSIGYW"
     gene            complement(13070..13522)
                     /locus_tag="ACHA1B_002318"
     CDS             complement(13070..13522)
                     /locus_tag="ACHA1B_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703057.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(13529..>13872)
                     /locus_tag="ACHA1B_002319"
     CDS             complement(13529..>13872)
                     /locus_tag="ACHA1B_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HFM8703058.1"
                     /translation="FGAIRERISQDNEQGRAARVFYEHIIVPRMEKVDWKRYAGCVAI
                     NSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAAKELAKVNIVAG
                     IAAAAASCALE"
BASE COUNT         4517 a         2731 c         1761 g         4863 t
ORIGIN      
        1 aacagaaaat ctttctataa aaaacaaaaa aaaacgatta ggctaggcta atcgtttttt
       61 gaacattctt aaaaaatcca aattattttt tataactgaa attgggtatt gatgaccatc
      121 gtttctgtag atagtaagca atcattttag gttttctatc tctagtaaag attcctttct
      181 tatttccttg cactcttaaa atcccttgac ttgttgcaaa atctgcaaaa ttccacactt
      241 gttcaccaac aaaattttca catgtatcta ttacttcgtg atttgcttcg taataagcca
      301 cttgatactc ttctgtaaac attgttggta ctgtatcatg aaatccagct actgtatctg
      361 ctccatattc tgtaaacatt attggcgtat caggacatct ttccatccat ccatctagct
      421 cttttttcaa cagatatttt gcatgtgcca gatcccctcc cgaaacatac caaccataat
      481 aacgatttaa acataaaaca tcgacaatat ctcctacctt acaaacatct ggcgttgatt
      541 ttagataagt aacgattgtt acaggtcttt tctgcggatc aagttcttta gttaattcaa
      601 ctaaaggttc aaaatattct ttagcacctt cggaatccga atctggttca tttgcaatag
      661 accacattac aacacttggg tggttcttgt cgcgttctat caattccttg atcaccgttt
      721 tatgagaatt ttctgttcgt atctctttcc acgtattatg tttttccaca ttatcatcta
      781 ataaagtggc catgaaattt aaatgtaacc ctactgcagg tacttcatca ataactacaa
      841 taccttctcg atctgctaat cgcataattt cttctgagta aggataatgt gatgttctaa
      901 aagaattagc acctatccat ttcattaaat taaaatcttt aatatttaca gcctcattca
      961 aaccacgtcc attaacatac gaatcctcat gcttaccaaa tcctttaaaa taaaaaggtt
     1021 tattattaat caaaaatttg ccattggtaa cctgaacact gcgaatacca aattcttctg
     1081 tataggtatc gatcacttta ttatcatcaa ttaaactaat tttcatacta tataaataag
     1141 cgtctagagg ttcccaaaaa attggattct taagctgaat cattcctttc tttccttcag
     1201 cttcagctac aagttgagcc tcttcgtcat atatcgctat taagattttt ccggtccatt
     1261 ctgtatcgat attgaattct acacttgcat ccaaatcagt tattcttgta ttaatagtaa
     1321 tatcacttat atagtctttc ggagttgtat ataacttaac aggtctatga atacctgcat
     1381 aattgaagaa atcaaaatta actaagtttt ccttttttat atccccattt tcctgtactg
     1441 tttccttcat aatccccaca ggtaaagtac tatcgtcaat aatattgttt acagcaactg
     1501 taattcgatt attcccgtct tttacaaacc gattaatttc agactcaaat ggtgtaaacc
     1561 cacctttgtg ttgagtaata aactttccat tcaaaaaaac ttttgcttca tgtgttgcag
     1621 atccaaaacg aagaactaat ctttcttcta ataatctttt aggaagagtc acttcttttt
     1681 cataccacac ccatccaaca tgatttctaa tgttctctgt ttcaaataaa tcattataag
     1741 aagagggaac tgaaatcgga taactctctt tttcatttat tggttctaaa gcaagttctt
     1801 cctgtaagtc atcatttgta tctaatttaa atctccagag accgcttaag tcaattactt
     1861 gcctcgtctc tgtcataatg ggatacaaca tataaaccac tcctatctaa atattaaata
     1921 aatgtatcct ttaaaccaca ataagcatct attggactta ctcccttaaa ttcagaaaga
     1981 cccattagtt tgtccaccaa tatttctaaa gtttcttgtt ttccatcata agtattaata
     2041 taagtcttta cttgaggtac atcagccaaa tgaaacggac actgtacaga tacaaaaatt
     2101 gttggaattt catgaatgta aaacggtata tccggagttc ctttacttgc tggccagaca
     2161 attcgttgaa ctgtgcctgg attaacatta gctatattaa tgatcaagtc atatttttta
     2221 gttaaatttt taattggtct cttagcagca tatattccag ctatattttt aattttttct
     2281 tcttgcgata atcctttcaa ttcttcttca ggtgaaatgt atttttcaac ttcaaatcct
     2341 tttgctgaca aaatctgttt caataaatca atggcttgag gtctatttcc agcaactact
     2401 tcaccaaacc caccttttac cccatgtaca tctactagta aaatcctttt atatttttct
     2461 ggtacaatag gccaaatatc ttgtttatct ttaactaatg taattgcttg gtcagccacc
     2521 tctttaaaaa ttgatttatt ttcaattaaa ccaatttttt ccagagcttc ttgcttaggt
     2581 aataaaattt gttcttttgc ttttttgtgt aatcccaatt tagcttttaa ccctaaaatt
     2641 ctttttaagg catctaataa ccgatcatca gtgataattc ctttacgata gccttccatc
     2701 atataattaa agtcttcatc tggatcatta aaaaatagaa atagatcaca tccagctgca
     2761 atagaagtgg gcaataattc tgatcgtttc attgccccag tcattcctaa catatgacta
     2821 gcatcagtaa ctactaatcc attaaatccg agttttcctc taagtaagtc agtgattaat
     2881 tcttttgata aagttgcagg aagtaaatct tcatctttca gatcaggatt aaaatgtttt
     2941 gaataagctg gcatatggat atgacctgcc ataattgaag gtaatccagc ttctattaag
     3001 cctgagtata cttttccaaa agaattatcc cattcttccg tacctaaact attaatacta
     3061 aaagatagat gctgatctcg ttcgtcaata ccgtcaccag ggaaatgttt agctgcaggc
     3121 aaaattccac tctcctgaat acctttcata taagctaaac taagttctaa aactttatca
     3181 gggttttgtc caaaagatcg actagaaatg ataggatttc tccaatttct attaatatct
     3241 acaataggag caaaactcca gttacatcca atagccgatg cttcaatccc agaaactctc
     3301 cctaattcat aagcatattt cgcatcattt gttgcaccaa tttttacttc tacaccaact
     3361 tcagtaccat ctgtacaagc tccgttacca cctgcttccg tattagcagc aattaataga
     3421 ggaattttac tttctgtttg taagatatag ttttgatcat atacctcatc agcagttcct
     3481 ggattatatc gtacagctcc aatatggtac tgattgacca tattactcaa gtaattttta
     3541 tcacgactag atcccatatt aacaaacaat tgacctattt tttcttccaa agtcatagaa
     3601 tcaatcgtct cttcaatcca agaaatagca tcttcatcta aattatatgg tttttttcgt
     3661 aaatctactt ttatagtcat tttctttctc ctctacttat tagtaagatt tttccaaaaa
     3721 gtatctatat atttttgttc aatatctaca taatctcccg ataaacattt aaataaaaca
     3781 tcagttctta agttttccca tgattctttt tctttattga ccaaaatagg ataaaagaaa
     3841 actttatttt tatttgcagc ttctagatca ccaggagaat caccaatcat taatatctta
     3901 tccaaatcac aaccattttc aattacactt cgaataatat cttctttttt tcctttatct
     3961 tgacaacaca gttcatcaac taatgataat aattcatgtc tttcccattc ttcttgaaca
     4021 gcttccttat tagctgagct tacaataatt atcttcccat attttttcag agcttttata
     4081 gtatctctag cacttaaaaa gggtttatct aatccttttg cttgactaat ctgttgattg
     4141 acttcttccg accattttaa agcttttaat aaatcctctg actgagaata ttctatttcc
     4201 ctcttcaaag atggattaga caattctttt gttagagata cccagtgctt taatcgatta
     4261 atcgatgtta catcattttt ttctaatgtt ttaactaaac ctaaaaatct gtttattcca
     4321 cgagtctctg aatataaatt aatattattc caatcctgta ggaatttttc tctatgatga
     4381 acatcaaaaa tctctgcagc aattggtccg aaaaagagat tgtgtttata agtcatcgta
     4441 tccataacac agccatctga atcaatacaa aatatccaat tattcatatt tctctcctat
     4501 ttatgttttt gttttaaaag ctcgcaattt tctaagactt tatctttaga taatggataa
     4561 aggaaaaata aaattaatcc tacaatcaga aaacaaattg atggaattaa tgttgaagcg
     4621 ttatataact tttctaaaac atctcccgtt tgtacatttg ctaaagagtc atagcctata
     4681 atagaaagag tccaacctcc gacgcctcca gctagagctt gacctatttt tctagcaaaa
     4741 gaatataccg catatacggt cccatcttct ctttgatcag actttacttc ttgatcatca
     4801 ataacatcag taatatttgc ccaaataaca gtattaaaca cacccaaacc catatagcca
     4861 accgaactaa gaattaagaa tacatacata ttactagctt ttatcaaaaa taagatcaaa
     4921 tatactattg ctgaaaagaa cattcctact gatgccagtt ctttttttcc atatttttta
     4981 cttaaaaaca aagttaaagg cgaaacaact attaaaacca aaataggatt gataaaattc
     5041 attaaaacta ttccctgtgc atcattatag taatcaggaa atacataatt attcatactc
     5101 ataattaata attgagcaag gagtaagaaa atagccgcac caattataga aagtaatgcc
     5161 ctatttttaa ctaacccttt taaagatttt aacaatgaaa ctttgtattg agattggtca
     5221 attcttactc gttcagtagt tagtttataa catattaaat aacaaataag tgcacatatc
     5281 gaaaatattc ccgcaacaat tgtaaaagtt gatccaccac gaactatttg agcgcctgaa
     5341 tcatctcttg tataaataaa taatggtgtt aatacaccaa tgaccaaact tgctaaagta
     5401 gctccaacat ttcggaatgt cgatagcatt gttctttctt ctgtaataga agtaatagct
     5461 gatgccattg atccataagg aatatttata gatgtgtaaa aaatactccc ccataatata
     5521 tacgtaacat acatgtatac taccttaacg ctcatagaag ctgaaatcat agaagtttga
     5581 tacattaaaa aacttgctaa agcgactgga ccactcattc ttaaaatcca cggtttaaac
     5641 ttaccctgct tagttgcttt cgatctatca acaatacgcc ccatagttac atcagtaact
     5701 gcatcgataa atcttgctac taaaaataat gttccaacgg cagctccgct tatccccaat
     5761 acttttgtat aaaagatcat taaaaaagaa ctagcaaaaa tgaaagtaaa atcgtttcca
     5821 aaatctccaa acatatatcc tattttgtct cttataccaa attttctttc catacaattc
     5881 tctcccttct gttgttaagc gttttcattc tgatgaaagt acgtactata ctctgaagcg
     5941 taaagagtca gtatttattt tttacatttc agagtattat ttgttttttc tcctaataat
     6001 tctttatctc ataaaactta tctatatatt tactagctac tcgacttact tcttcaaaat
     6061 cacctttttc aacagaagcc aataaattcc cacctacacc aactgcaaca actcctactt
     6121 caaaccaatc ttctaagttc tctatactta ctccgccagt aggcattata tttacgtgtg
     6181 gtaatggagc ttgataggct tttacaatgg atggaccaaa agcagaacct gggaatagtt
     6241 taatgatatc tacgccagca gtaagtgcct cctttatctc agtaattgtc atacaacctg
     6301 gtaaataagg aatttgatat aaattacaaa tctcagctgt ttgtcgatca aaagatggac
     6361 taacgatata ttctgcccca gccataattg cgatacgagc agtaaacgca tctaaaaccg
     6421 taccggctcc gattattaca tctttttgat cagcatattt tttagcaatt tctttgatta
     6481 tttcttcagc attaggaact gtaaaagtta gttcaatccc tttaattcca cccgcaataa
     6541 ttgaatttat tgctttaatg gcctcatcct tatttttccc acgtacaacc gcaatgactc
     6601 cagccgcttc taacttactt aaaatttcta cttttttcat atctatctcc ttcctttatg
     6661 gatacatact ttgtctagct gtactaactt acaaagaata aatttaagct tttatttcaa
     6721 gtattatttt ctacttccga tttcaaaaaa attaaaataa ttatacgcat tacgataaca
     6781 aatattctcc actatctgac taagatacat ttcatcatct ggaattcggc ctgctttaac
     6841 ccactcgctt agtaattgac ataatactcg acgaaaatac tcatggcgag gatagcttag
     6901 aaaacttcga gaatcagtca acatacctgt aaaattcgac aacaaacttt gttgtgccat
     6961 cgtagtcaac tgttgacgca ttccttcagc tgtatcattg aaccaccaag cacatcccaa
     7021 ttggattttt tgaatcatac ccccttggaa gctttgcatt gctgttgcta gtggaagcca
     7081 atcagttgga tttaatgaat ataaaattgt ttttggtaag cacccactct tttcagcggt
     7141 atcgaacaat gctacaacat tttgtgtcaa actagcttga tcccccatcg aatcaccacc
     7201 gacatctact ccaatttgtt cctttaatat acttgaatta tttcttaaag catttaaatg
     7261 catttgcatc gtccaaccat atcttgtata ctcagacatc aaatgtaatt gaatacctgt
     7321 aacaaattgt gcaatttctg ataaatggaa atccgttttt cctgctaaag cttttattaa
     7381 cagattgtcg agtatttttt catctgctat ttcataaaaa taagtattca aaccgtgatc
     7441 tgctaatcga cagccaattt gatgaaaatg atccactcgt tggctcaatg cttgcttcaa
     7501 cccattaaag tctttgattg gtatagccgc tgtttgacta agttttaaaa tatagttcga
     7561 aaagcctgat gatttgatac tccagacctt atctggacgg aaagtaggta ataccttgaa
     7621 agaattatcc tgtttagaaa gctcagtatg ataccacaag tcatctgtag gatcatccgt
     7681 tgtacagatg gctttcacat ccatcatctc caacaattct ttcgggcgat aggaatccgt
     7741 ttgaattttt tcgttagcac gtcgccaaat ttctggtgca ttcttctcag aaattgtcaa
     7801 atcaatatca aagtaacgtt gtaattccaa atgagaccat tcaaaaatag gattacctgg
     7861 cgccttctcc actgttttta caaaagctaa aaatttttca taatcatcac ctggaccact
     7921 gatcaactct tcttctatac cattagctcg catcaatcgc catttataat gatctccagc
     7981 tcctttatca tttaaccata cctgagtcaa attcttgtat tgcttatttt ctagcaaata
     8041 tgctgggtct aaatgacaat gatagtcgat aattggttgg tgttttgcaa atttatgaaa
     8101 aagtctttta gctatttcat tctctaataa aaagttctta tctaaaaaca tatttaaaca
     8161 ctcctttcct tccgttagtt tttagaagag aaaatttttc ctctaaataa actcccttat
     8221 ataattattt actcgccccc ttttcaagcg cttcccaaat accatttaaa taaactgcac
     8281 ctagagctcg gtcatataat ccataaccag gtctaccggt ttctccccaa atcatccgac
     8341 catgatctgg acgaatatag ccattaaatc cattatcgta cattgttttt aatatcttat
     8401 acatatctag agaaccatat tctgatttat gcggcgcttc gtaaaaatcg agtccattgt
     8461 cacttaaata tttgatatta cgaacatgtg caaaaggaat ccgatcccgt tgacaaaatt
     8521 cagatagaat ttcatagaca tcattatctg gtcgttctgc aatacttcca gtacataatg
     8581 taataccatt agaaggagaa tccactacat tacacaacca atctaaatcg tcacgatttt
     8641 taacaatacg aggtaatccg aaaatggaat atggtggatc atctgggtga actgccattt
     8701 taatcccaac ttcttcacat gtcgggataa ttgctttgag aaaatatgca aagttctctc
     8761 gtaatttctc ttcatcaact tctttatagg cttctaataa ttgcttaatt tgtgataacc
     8821 gatgaggttc ccaacccggc aattcaaaat tattagtaga attttctact tctctaataa
     8881 tttcctccgg atcagtaggg atattttttg aaatataggc taacgtagaa gacccatcat
     8941 ctaaacgata atccaaatcc gattttaccc aatcaaatac tggcataaaa ttataacaga
     9001 taacctcaat cccaaattct gccaaattgc gaatcgtctg tttataattc tcaatgtatt
     9061 gatctcgtgt tggtaaacca attttgatat catcatgaac attaacactc tcaataactt
     9121 tcaaggtaag tccattggct tcgacttcat cttttaaaga tttaattcgt tctctcggcc
     9181 aaacctctcc ggctggtata tccattaatg ttccaacaat tcctttcatt gctgggatct
     9241 gacgaatttc ttgtagtgag attttttctt catttgcccc ataccatcta aaagtcattt
     9301 ccatagttac tttcctccaa cttctgttat atatttattg attgttttac gaactgcttg
     9361 aggacctact agcatttcgc aaaagatttt ttcagttttc tttcctaccc caacttgata
     9421 taaatctaaa ccaaagattt ctttattttc taaaatttcc tgtaccgcac aatgaatctt
     9481 tgaaggatct tgttcaccta atttcaatac tgataattta tcctgcaact ctaccaataa
     9541 cggatcagga cttggcacaa aattttcccc ttgatcatcg actgccagta aataacgtaa
     9601 ccaagcagca atagcgatag gaataaatgt tagattttct gcatttccgt ctttttcgac
     9661 atacttttta attgtttcac catagcgaat cgctactttt tgagaagtat ctgttgcaat
     9721 tcgttgtggt gtatctggaa tatagggatt aggcaaacgt ttattaatta cttcatcaat
     9781 aaattgtttt ggatcaataa tgcctggatt ttcaactact ggtaaacctt ctaaataacc
     9841 tattcctttg attaaaccaa ccaaatcatc atcctgcatc tctgctgaaa ttgattgata
     9901 tcctagcaga caacctgtta ctgccaaagc agtatgaagt ggattcaagc ttgtcgtaac
     9961 cttcatgatg tctgctttat caaccgtctc tctatctgtc ataatcacac cagccttttc
    10021 caatttaggc cggccatttg gaaaactatc ttcaataact aaataatgaa ctacctcagt
    10081 attagtgaaa gcagcaatat tggtatgttt ttttgtgtga atgatatcta aatcctcgag
    10141 ccccatcatc aatagatctt cctttacatt ctctgaagga tttggcgtaa ttcgatcaat
    10201 catactccaa ggaaaagtca ctttttcttt atcctttaaa taagcaataa atttttcaga
    10261 aacatatcct tctttttgcc aagcttctgc aatcgtaaaa atactatctt gaaaacgttg
    10321 accattctgt gagaaattat cagtagaaac catcgcaatc ggcaactctc cagcattaaa
    10381 tctgctatat aacaaggatg ttacaatact catcgtatgt tgaggattgc taggtccaga
    10441 tttgatatca gctttgacta ccgaaaagaa ttgcccttta gaatctttta aactgtaacc
    10501 tttttcagta atagtaaacg ttgtaaactg taatttagga tcttcaaaat atttaaccac
    10561 tctttgatag tccgctatat tcttcggatt gcaatataaa ctatcagccg ttactgccaa
    10621 aagtcttttt ttgagttcac catctccact cataacaatt tccaaaatgt cattgttata
    10681 gtcatgataa gctttttcca ctacttcttc atcaaatgtt tcacacacaa ctactcctgt
    10741 ttctaattca ttttgatctg ctaagcattg agcaatttct gcatgaaatc ctcgataaag
    10801 atttcctcca ccaaaatgaa gccatactgg atgttgctgg ccttcttgct taacttcttt
    10861 gacatcaaaa cacggcagta gaatctgcat ttcattgaat tcttcgatag aattttgcca
    10921 atttttaatc gaaaccataa ttaacctcct caaactgata tgttagtttt gatacatttt
    10981 atattttaaa acccattgta accgttgtca atataaaaag ggaataaact tgcttttttc
    11041 taccatatca gaatgattgt attttttatt cagaaaaata aaatactcct tctttttgga
    11101 ctgattttat cgaaacttat tttttctttt tttcatgtat tcttttattt ttataactag
    11161 tgtattactt caaaatttga tattatatgg catgaacaga attaaaatat cagttaaaat
    11221 aaaagttaag gagcattgtg tatgacaatt aaaactagtc tccaaaatca agcttaccaa
    11281 tctattcgcc gacaaattat ctatgctgac ttagaacctg gaaaaaaagt atcagaaaaa
    11341 aaattagaag aaacactttc tattggtcgt acaccaatac gtgaagcact gattcaactc
    11401 cgacaacaag gtcttgttga tacaattcct caaagcggaa attatatctc attaattgat
    11461 ttagattcgg ccaaaaatgc tcgatttgtc agagaacatt tggaacgaca aattatgtta
    11521 gagtgttgtg ccaaaatgaa taaccaaaaa aaacggattt tagaaactat aatttcagaa
    11581 caagaaaaag ctgttagtca aaaaaatgct cgtagttttt ttcataatga taatttattc
    11641 cataaagctt gttttgaaat tgcagagcga gaagaagtat ggcaatggtt agaaaataac
    11701 aatacacact tagaacgatt tcgatggcta cgagtaaaaa cggaaggatt aaagtgggaa
    11761 aaaattatgg aacaacatta tcaactattt gaggcattaa caaaacaaga tccagaagaa
    11821 gctaactttc taacatcgtt gcatcttcat ttaatgctta atgagcaaaa tattgtttta
    11881 gctactcatc caaaatattt caaaaatata taacttttaa ctctttttaa attaaatggt
    11941 tgttctgatc agaaaaatat cgcttgtttt cttattatgt aatatatttc ataaactatt
    12001 ctgcataaca actattgttt gtacttttta cattggataa ctaattatga ctgctgataa
    12061 cttttgatat taaactagta tctccaatac aaataaaaaa tagatatctt gttcatcaaa
    12121 attagttcgt ggatacttac cttcatttac atcattcagc ggtttcccat tttcttttat
    12181 tctattattt cattttctaa tagacttggc ttcatttcgc aatacttttt ttcaataggc
    12241 atcaaattgg tgttgtttag atatttagtt gtagttttgt gacatgataa gtatgctcct
    12301 ttttctcttt tccactaata caacgatcaa agggtgcttt tttcaaaaaa ctagaaaaat
    12361 caaaataaga ttcgtatttt gattctatat atcctgtttc aactacatct tatatttcac
    12421 aatagaataa atagcctttt gcatagctgc ttaacttata agaaattgca atttacttct
    12481 tcaaagtgaa aacgaatatg agtaaaataa aattattctt cttacagata attaaaaata
    12541 gcgcgtaaca aaaatcggca ttcaatcaca taattaggat tgatgccgat tacttatatt
    12601 ctacgtatag ttttagtatt cttatttttt atcaccagta accaattgag aacagcccta
    12661 aagcagaata gtcttttatc tcaaaacgct taatttcagg cttaggaata tgaataatct
    12721 tttgagtata ttctttctct tttaatctta ctgaagaaat accactgcct atctttttta
    12781 caaatatttc atttggtgta cagactaata aaacaatatt tgtaatcaat ccttgcacta
    12841 aagaattaaa aggaagacta tttaaaacag ggtgtgcata actataacat gtgaagtagt
    12901 tattttgaac tttaactttt aaaaacttta aaaataatct tatttgttct tctaaacaat
    12961 catctatact catataatca ctccactaat taatctcccc aaaaagacac agcattaaga
    13021 gatataccaa cacaacagtg caaataactc tacatcttcc ttcgcaacct tatttcaata
    13081 aaccataaaa attatttttt aatagaaact gaaaattaaa actagaaaaa gtagttttac
    13141 cgaatgtaag agcatcatca ccatcaatat agaaatacat tcttttccag ttacatttaa
    13201 tttttaaaca aaattctccc caaaaaggaa ctttttctag tgaaaacttg gtaatctctt
    13261 tgtaattaat tcttgttaaa gaataattaa acacttcatt tttacttgtt attttttcat
    13321 tgactataac tagttcatct ggtaaaaaaa ttaaccaaca aacatcgaca aacagtaaat
    13381 gatataatcc atttccacct ccaagcatat tcaatactgg tgaacatgcc ttagaaacac
    13441 gaatatagtt atggtttaaa tagatatttt ctttaaacat tgcttgttta aaagccatat
    13501 gctcttgttc taaacttttc ataaactttt actctaatgc acagctagca gcagctgctg
    13561 caattcctgc tacaatattt accttagcta actctttagc tgcagctttt cctaattgtt
    13621 tttctgcaat ttttaataat aaatccgcag ctttttcaaa attaaaagct tttaatgctt
    13681 caataaaatc tccctgcgta cctatagccc aagccactcc tcctccagga agagaattaa
    13741 tggctacaca tccagcatat cgtttccaat caactttctc cattctagga acaataatat
    13801 gttcataaaa gactcttgct gctcttcctt gttcgttatc ttgactgatt cgttcacgaa
    13861 tagcaccaaa at
//
LOCUS       DAYYEF010000064        13808 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000064 DAYYEF010000000
VERSION     DAYYEF010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.067"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="ACHA1B_002320"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="ACHA1B_002320"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004802 - transketolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HFM8703059.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="ACHA1B_002321"
     CDS             complement(2261..2512)
                     /locus_tag="ACHA1B_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HFM8703060.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="ACHA1B_002322"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="ACHA1B_002322"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0009432 - SOS response [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HFM8703061.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="ACHA1B_002323"
     CDS             3462..3680
                     /locus_tag="ACHA1B_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703062.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="ACHA1B_002324"
     CDS             complement(3969..4481)
                     /locus_tag="ACHA1B_002324"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0006168 - adenine salvage [Evidence IEA];
                     GO_process: GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HFM8703063.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="ACHA1B_002325"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="ACHA1B_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008409 - 5'-3' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HFM8703064.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="ACHA1B_002326"
     CDS             complement(6934..7377)
                     /locus_tag="ACHA1B_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA
                     domain-containing protein"
                     /protein_id="HFM8703065.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="ACHA1B_002327"
     CDS             complement(7378..8166)
                     /locus_tag="ACHA1B_002327"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HFM8703066.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /gene="rnz"
                     /locus_tag="ACHA1B_002328"
     CDS             complement(8163..9104)
                     /gene="rnz"
                     /locus_tag="ACHA1B_002328"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016891 - RNA endonuclease activity,
                     producing 5'-phosphomonoesters [Evidence IEA];
                     GO_process: GO:0042780 - tRNA 3'-end processing [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HFM8703067.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="ACHA1B_002329"
     CDS             complement(9281..9868)
                     /locus_tag="ACHA1B_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HFM8703068.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11402)
                     /gene="obgE"
                     /locus_tag="ACHA1B_002330"
     CDS             complement(10089..11402)
                     /gene="obgE"
                     /locus_tag="ACHA1B_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003924 - GTPase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HFM8703069.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11690..12700
                     /gene="gap"
                     /locus_tag="ACHA1B_002331"
     CDS             11690..12700
                     /gene="gap"
                     /locus_tag="ACHA1B_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_function: GO:0051287 - NAD binding [Evidence IEA];
                     GO_process: GO:0006006 - glucose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HFM8703070.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12785..13720)
                     /locus_tag="ACHA1B_002332"
     CDS             complement(12785..13720)
                     /locus_tag="ACHA1B_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM8703071.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3808 a         3096 c         2435 g         4469 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11701 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11761 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11821 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11881 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    11941 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12001 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12061 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12121 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12181 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12241 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12301 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12361 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12421 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12481 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12541 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12601 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12661 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat caatcgataa
    12721 aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct acttttaaac
    12781 tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat ttttcaggat
    12841 ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct tttggtccct
    12901 tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct tcgtctccat
    12961 gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt gcttcaccga
    13021 aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc ggaaatgctg
    13081 gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa gaataaccgc
    13141 aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc atcataactg
    13201 ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca ttgttttcta
    13261 gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat ccaatgtaat
    13321 ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa cccatatcat
    13381 gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca tgagccacaa
    13441 gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat ttcagaccgt
    13501 cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat ttatgtgcat
    13561 ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag tctttctcag
    13621 aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca acaatcagag
    13681 ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca tctcatttct
    13741 cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc aatgttcatt
    13801 tttataac
//
LOCUS       DAYYEF010000065        13702 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000065 DAYYEF010000000
VERSION     DAYYEF010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13702
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.068"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..901)
                     /locus_tag="ACHA1B_002333"
     CDS             complement(<1..901)
                     /locus_tag="ACHA1B_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HFM8703072.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(925..969)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1184..2152
                     /locus_tag="ACHA1B_002334"
     CDS             1184..2152
                     /locus_tag="ACHA1B_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM8703073.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2265..2543
                     /locus_tag="ACHA1B_002335"
     CDS             2265..2543
                     /locus_tag="ACHA1B_002335"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8703074.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2661..2897
                     /gene="secG"
                     /locus_tag="ACHA1B_002336"
     CDS             2661..2897
                     /gene="secG"
                     /locus_tag="ACHA1B_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015136 - sialic acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0015739 - sialic acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HFM8703075.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3000..3755
                     /locus_tag="ACHA1B_002337"
     CDS             3000..3755
                     /locus_tag="ACHA1B_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFM8703076.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3758..6115
                     /gene="rnr"
                     /locus_tag="ACHA1B_002338"
     CDS             3758..6115
                     /gene="rnr"
                     /locus_tag="ACHA1B_002338"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HFM8703077.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERCAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6137..6601
                     /gene="smpB"
                     /locus_tag="ACHA1B_002339"
     CDS             6137..6601
                     /gene="smpB"
                     /locus_tag="ACHA1B_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HFM8703078.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6903..7622
                     /gene="atpB"
                     /locus_tag="ACHA1B_002340"
     CDS             6903..7622
                     /gene="atpB"
                     /locus_tag="ACHA1B_002340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HFM8703079.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7675..7890
                     /gene="atpE"
                     /locus_tag="ACHA1B_002341"
     CDS             7675..7890
                     /gene="atpE"
                     /locus_tag="ACHA1B_002341"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HFM8703080.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7981..8505
                     /gene="atpF"
                     /locus_tag="ACHA1B_002342"
     CDS             7981..8505
                     /gene="atpF"
                     /locus_tag="ACHA1B_002342"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045263 - proton-transporting ATP
                     synthase complex, coupling factor F(o) [Evidence IEA];
                     GO_function: GO:0015078 - proton transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HFM8703081.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8492..9034
                     /locus_tag="ACHA1B_002343"
     CDS             8492..9034
                     /locus_tag="ACHA1B_002343"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HFM8703082.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9057..10613
                     /gene="atpA"
                     /locus_tag="ACHA1B_002344"
     CDS             9057..10613
                     /gene="atpA"
                     /locus_tag="ACHA1B_002344"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HFM8703083.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10627..11529
                     /locus_tag="ACHA1B_002345"
     CDS             10627..11529
                     /locus_tag="ACHA1B_002345"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HFM8703084.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11552..12958
                     /gene="atpD"
                     /locus_tag="ACHA1B_002346"
     CDS             11552..12958
                     /gene="atpD"
                     /locus_tag="ACHA1B_002346"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_component: GO:0045262 - plasma membrane
                     proton-transporting ATP synthase complex, catalytic core
                     F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HFM8703085.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12972..13394
                     /locus_tag="ACHA1B_002347"
     CDS             12972..13394
                     /locus_tag="ACHA1B_002347"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0045261 - proton-transporting ATP
                     synthase complex, catalytic core F(1) [Evidence IEA];
                     GO_function: GO:0046933 - proton-transporting ATP synthase
                     activity, rotational mechanism [Evidence IEA];
                     GO_process: GO:0015986 - proton motive force-driven ATP
                     synthesis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HFM8703086.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4530 a         2450 c         2988 g         3734 t
ORIGIN      
        1 tttcggaaaa aagacgagta tctacttttg tcataatttt actgttagca ggtttctgcc
       61 aaaattcata acgatcaacc aatgtttgtc cacgacttat tccctgagtt tccacagcgg
      121 tgaagctttt gaaaccttca cagatggccc cctcgatgaa ataagcaaca gctaacggat
      181 cattgatgac acatcctaaa attctttctt gtttccagtg gaagtcaaaa taaaaacgag
      241 tgatcgcttt taaatactct ccctcttcag gattcatttg acagcagtat tcgaggatag
      301 tcggtgtcaa gacgatttct cttgtcacat ctaacccaac catttctatc gtttgtttga
      361 gattctcgaa tacataagaa gctgcttcag gatcacacca gtaattgtat tcagcaactg
      421 gcgaacagtt accatggctt ttgtaagttc cacccatcga gacaaaacga tccatatgtt
      481 tcccaatatt tgggttgact ttcaaagcaa aagcgatatt ggtcaaagga cccaaagcaa
      541 tgactgatgt atttgtcttt tctttgaaat aatcagccaa aaaatcaacg gcatggagag
      601 gttctgcctg ttttctcaag atcatcggga aatttgtttc ccctaaacca tccataccat
      661 gagtgtcttg tgcactgatg aaaggttgct tcaaaggttt ttccattcct tgataaacag
      721 gaatgtctaa acgatcacag cgttccaggc atttcagcac attctgcgta cctatatctg
      781 cagggacatt cccacaaact acggtaatag caactacttc gatatcaggg gatttgacag
      841 ctaatgataa agctaaagtg tcgtcgatcc ctggatcgca atcaataatt acttttcgca
      901 ttatttccaa tctcctttct ttagagatac ttagtttttt attctgggaa gtttccgaac
      961 cagtccaaga cgagcgtctt gattataatg cacgaaatta gtatactggc ttttattgcg
     1021 aatgtaaatg ctctcttaca agtaaatcta ttgaggagaa ctttaagtaa atgatacaat
     1081 gaaaaagaaa tggaatttac gtgtgccgaa aataaagaat cctatggatc ggtacattgg
     1141 ataatagata gattatagtt tggcagaaag cggcgggtgt acaatggtta ttttttattt
     1201 cattcttatt ctgataatta tagggatcag ttaccatttt ctttcttatt tttatgcaaa
     1261 gaaattagta agagcgggag tacagagagg atatgactgg tatgaagaca ctggtcatcg
     1321 tttgatggac cctgctgcag tcacgtcagt agaaaaaaaa cgacaaaaat tagaagaaga
     1381 gtgtgaaagc ttttgggagc agggaacacc caaaacaatc aaaagttatg acgggttgaa
     1441 actagctggt cagatgttca tccatccaaa taagcagaat aaatgggtca tttgcgtaca
     1501 tgattaccga agcacaggga aaagagacat gtctcatata ggtaaaagat atgcagagaa
     1561 aggattcaac gttcttgtac ctgatttacg tgcgcacgga gaaagtgaag gagaaatcat
     1621 cggaatggga tggctagatc ggctagattt aattgcctgg atccaactca tcttagatga
     1681 acagccgaat gcgtccatta ttttacacgg cggatcaatg ggagcttcta cgatcatgat
     1741 ggcaagtggt gaaaaacttc catcagcggt caaaggattt attttagaca gcggatatgt
     1801 ttctgtttat gcagaattcc gatatatgtt aagtaaaatc actgtctttc ctaaaaaaat
     1861 ggtcatgaga tatgcgaatc attatgccca gaaatacgcc ggttactcct taaagcaagc
     1921 atcagctacg agacagcttg gcagcaacca tctgccttta ttagtcatcc atggtgaaag
     1981 agatcatttt gtccctacag aagcagcgta cacgattcaa aatgctacgg caggggataa
     2041 agcactgctg cttgttccag aagcagaaca cttggaagca tcgatgaaag atccgaaaac
     2101 ctattggaca gtgatttttt catttattga acaaagaata acgatggatt aattttctct
     2161 tcttttttgt aagtaattcg aggataaata attgtttata gatctggaga ctgctaaaat
     2221 aaggtaggaa taaaaaaata tcagttattt gaggagtgcg gcatatggaa atcaaagaag
     2281 aaaaaaatcg tcttgcttta ttcaatgatg agcaacaaga gattggagaa atgacatggt
     2341 cagatgcggg cccagacatc atgatcattg accatacatt tgtagatcca gcatatcgtg
     2401 gtcaaaagtt agctgaaaag ctagtgtata ctggagtaga attagcaaga cgagacggga
     2461 aaaagatcat tcctttatgc ccttatgcaa aaaaagagtt tgaaaagaaa ccagaatatc
     2521 aagacgtctt acgtcagtca taagaataac agctgaaagt tttgaacttt cagctgttat
     2581 tccatttata tagagttgtc acggactttt atctatgata aagttaaaga gacgatatct
     2641 tttgggaagg aggctgcgat atgtataatt taattttggg aatcgtgatc gttttatcga
     2701 ttgttatggt cattgcgatt atgatgcagc caagcaagca aaatagtgca gcgagtgcat
     2761 ttaccggcgg tgcggatcaa ctattcggca aacaaaaagc tcgcggcttt gaagctgtca
     2821 tgcagcgatc aactgcagtt atgggagcta tctggatgat cttattattt gtcctagcat
     2881 atttatcttc gaagtagttg aataagcctc tcgcaaaacg gcgggcggct ttttttattg
     2941 caaagagaac gcttaagaag aagttatgaa agaaactatg gtaaaatgag gcgaaagagg
     3001 tgagacgagt gagacaatta ccaaaacccc tttatgcaaa acatggaaag cgagcggttt
     3061 tgctgcttca cgcttactca ggaagtccaa acgatgttcg aatgctcgca cgatttttgg
     3121 aaaaagcaga ttatacagtt tatgcgccgc tttttaaagg acacggaaca atggagccat
     3181 atgatatctt gcaagaaaaa gcagaaagct ggtgggcaga cactaaaaaa gccatccatt
     3241 ttttacagtc tgagcagttt tctgatattg ccgtattagg attatcaatg ggcggcatct
     3301 ttgctgtacg agcactagaa gaagaatcag tgattggcgg cggttttttc tgttcgcctt
     3361 tgtctcctgt aaaaacaaac gtgcctgaaa actttgaaaa atacgtacgt caagtgctga
     3421 agacagcagg taaatcagag aaagaaatca atgaaaaagc agttgcttac cgctcgttag
     3481 ctgaacaaca attaatggat atacaagatc aggcagcaat cgtagaaagt aggttgtcag
     3541 atatccaaca gccgatattt ttagctcaag ctgggaaaga tgaaatgatc gaccctaatg
     3601 gcgtatttga aactgcacgc aagttgagcc gtcagcgagt gacacttcaa tggtatcctg
     3661 aaagtggtca tgtgattaca gttggtacag caagacgcga attagaaaaa gacgtcttgg
     3721 aatttttaga aaaattacct tggaatgagg aataaatatg acaaaagaaa cgataaaaga
     3781 gaaaattctc tttttcatgg aaagcagtcg caaacgcagt ttttctatgg aagaaatcgc
     3841 tgaaggttta gggttccaaa aaagcgatga ttttaaatta ctagtacaaa cgattgctca
     3901 aatggaaaga gaacagagta tagttttcaa taaaaaagga aaagtgaaac ttcctttaaa
     3961 accaatcttg atcgaaggaa catttcgagc aaatgaacga ggatttggat ttgtaacgat
     4021 tgatcccgaa gaagatgaca tctatatccc aaaagaagcg actggttttg caatggatgg
     4081 agacaccgta gcaatcgata tcatgaagcg agcaaataca gatatggatc gcggagcaga
     4141 ggggaaagta gtcgagattc gagaccgggc gactactcag ttagcagggg aattcgttgc
     4201 ttattcagaa gaagaaatac aagaaacaga tctttacggc gttgttatcc cgaaagatag
     4261 aaagctcaac caatttaaag tatatgcagc agcagaggga gttcgtccag ttgacggaag
     4321 tattgtgctg atcgaactga cccattaccc tgaaaaaggg tatgcgacta gtttagaagg
     4381 gataatcaag caagtgattg gtcataagaa tgaccctggc atggatatcc tctcaattgt
     4441 cgtggctaat ggtatcccta cgaaatttcc tgatgatgta ttgtctgaag cagatgaagt
     4501 tccagatcaa atcagcgaaa aggatataac tggacgtaga gatttaagaa atcagctcat
     4561 tgttacgatt gatggagaag atgcaaaaga tctagatgat gcagttacgg ttaaaaaatt
     4621 agataacggt aattattttc ttggagtaca cattgcagat gtttcttact atgtgacaca
     4681 aggcagtcaa ttggacagag aagcatatga aagagggaca agtgtatatt tgactgatcg
     4741 agtgattccg atgatcccgc aacgtttatc gaatggtatc tgttcactga atccccatgt
     4801 tccaaggctg accatgagtt gcgaaatgga gattgatcca aatggacaag tagtctctca
     4861 tgatattttc ccaagtgtga tccaaacaac agaacggatg acctacacag ctgtcaatca
     4921 aatcttagaa gatcaagacg aagaaacgat gcaacgctat gctcagctcg tacctatgtt
     4981 ccaagaaatg ggtgaattgc atcgaatcct tgaaacgatg cgaatcaaac gtggcgcgat
     5041 ttcttttgag gatcgcgaag cgaaaatcct tgttgatgct gaaggacacc caaatgacat
     5101 ccagctaaga agcagaggaa ttggtgaacg cttgatcgaa tctttcatgc ttgcggccaa
     5161 tgaaacggta gctgaacatt ataataaatt aaatctgccg tttatttacc gaatccatga
     5221 acagccaaaa gaagaaaaaa tgcagcgctt ctttgatttt gcttcagctt tgggcattct
     5281 ggtccgagga acgaaaggaa cgatcacacc aaaagattta cagcatgtga tcgaaggagt
     5341 agaagacaaa ccagaagctg cagttatcaa tactatgttg ctaagaagca tgcaacaagc
     5401 acgctattca gaagacaatt ttgggcatta tggcttagcg gcagattact acacacactt
     5461 tacatctcct attcgacgct atcccgatct aatcgtccat cgtctgatcc gttcttacag
     5521 tgaagataaa agtgaaagca atcaaagttc gtgggctgcg gaacttcctg aaattgcaga
     5581 tcatagttct aagatggaac gttgtgcagt agaaacagaa cgtgaagtag attccatgaa
     5641 gaaagcagaa ttcatgatgg acaaagtggg agaagaattc gatgggatca tcagctctgt
     5701 tgtgaaattc ggcctgttta tcgaactgcc gaatacagta gaaggattga tccatatcaa
     5761 tgaattgaaa caggactact tccattttgt tgaaaatcat ttagctcttg taggtgaaag
     5821 aactggtctg acttttaaaa tcggacaaaa agtgcgcgta aaagtagtca aagctgatcc
     5881 agatgaacga gcagtggatt ttgaactcgt ttccgcagaa gaggtcactg cgttggaacg
     5941 tccaaaagca cgcaatggaa aatttggaaa acgagaagga aaacaagcag gcaaacgctc
     6001 agaaaaaaat ggcaagaaga acaaacgata tagtgatagt aagcaaacgt tcggtaagaa
     6061 aaaagggaaa aagccatttt acaaagatgt caaaaagaag aaaaagaaaa aataaaatga
     6121 gttggaggaa acagctatgc caaaaggcga gggaaaacta attgcacaaa acaagaaagc
     6181 tcgccatgat tattcgatca tcgacacgat ggaagcaggg atggtcttgc aaggaacgga
     6241 gatcaagtcg atacgaaaca gccggatcaa tctgaaagat ggatttattc gcgtccgcaa
     6301 cggggaagct ttcttgcata atgttcatat cagtccttat gaacaaggaa atatttttaa
     6361 tcatgatccg ttgcgcacga gaaagttatt attacacaag aaacaaatcg ttcgtcttga
     6421 aaacgaattg aaaaacactg gaatcactgt tgttccttta aaagtctata ttcgtaacgg
     6481 ctatgccaag gtattgattg gtctggcaaa agggaaaaaa tcgtatgata aacgggaaga
     6541 tttgaaacga aaagatatcg atcgacaaat tgatcgaaca ttaaaaaatt tctctagata
     6601 atttcattat cctttttcgc atattcggtg cttttgcttt tacttaatga taaaatttgt
     6661 tagcatttaa tctgataaaa catgattatc acaggttttt tcttagatca ggagcaccgt
     6721 gcatggggaa aaattcgctt cgtttttgac tgaaataaaa aagtgtctaa ttttcatgaa
     6781 aatgttttga attttctgtt tcatggtggt atgataccgt gtggttagaa accgattgga
     6841 aaaaaccaga tacgcacatg aattgatttt atgtgaattt cggggaaaag aggtgaaatg
     6901 gattggatga acgctcgcta acgtttcaca ttggaccaat ttggtttgat ggtacagttt
     6961 gtataatggt gttactgacc tgtttgattg ttttcttctt agcttacttt tttacaagaa
     7021 atcttaagtt gaaaccaaca ggcaaacaaa atgcgataga atgggtcatt gattttagtc
     7081 gaggaatcgt aacagataat ctgcctagaa aagaattgag caatttccat ttgttggcat
     7141 ttacattgtt tttatttgtt tttgttgcaa acaacatagg tttagtaaca aaaatcgtct
     7201 tacctaacga aacaacactt tggaaaagcc cgacagcaga cccgtttgtt actttaactt
     7261 tggcatttat aatgatctta cttactcact tattcggggt gaaaaagtta ggcttcaaag
     7321 gatatttcgt aaattcgttc ttgaaaccct atagttttat gtttccgatg aaactgattg
     7381 aagaatttac aaatttatta acacttgctt tacgtcttta tgggaatatt tatgcggggg
     7441 aagttttgct aaccttgatt gcaaaaatga tgacaagctt aggctggttc tcattaccat
     7501 tagcaattcc attagagatg gtctggatcg cgttctcctt gtttattggg agcatccaag
     7561 catttgtctt tgtcactttg tcaatggttt atatgagcca taagattgaa gtagaagaat
     7621 aatactcggt taaaaaacaa actactattt atctatttta ggaggaaaac aattatgaat
     7681 tatatcgcag cagcaatcgc aatcatggga gcagcaatcg gagccggtta tggtaacggt
     7741 caagttatct ctaaaacaat cgaatcaatg gctcgccaac ctgaaatgtc tggtcaattc
     7801 cgtacaacaa tgtttatcgg ggtagctcta gttgaagctg ttcctatctt aggggtagtt
     7861 atcgccttga ttctagtttt tgccgtttaa ttgaatcagt attaaggcag aaacaacatc
     7921 gtttgttact gcttttttac atggaaacta gaaatactcc aaagaaagga aggctcgcct
     7981 atgctgaatc aattggcaat tgcagaagtt ggcaatgcga tgttaggtaa tatcatcgtt
     8041 gtcagcggct catttttgat actactggct ctcttgaagc actttgcttg gggaccaatc
     8101 agcgatattt tgaaaaaacg tgaagacaag atcgccaatg atttagattc tgcagaacaa
     8161 tctcgcatca actcagcgaa aatggaacaa gaacgcgaac aacaattgtt agcctctcgt
     8221 tctgatgcag ctgatatcat caaaaatgcg aaagaaagtg gagaattaag ccgccaaaat
     8281 attttgaagg atgctcaaga agaagcagct cgtctaaaaa gcaaagccca agctgatatc
     8341 actgtagaac gtgattcagc gctgaactct gtaaaagacg acgttgcaga actctctctt
     8401 caaatcgcgg aaaaaatctt gaacaaagaa ttatctccag aaatgcatga atcattaatc
     8461 aatcaataca ttgaaggtct aggttcttca aatgaaacta gataaatata cagtaggaag
     8521 acgttacggg aaagctttat ttgaactggc gatcgattca aatcaagcag aagaaatcta
     8581 tcaagatctc gtaagtttac gtcaaatcta tgaacaagta cctggattag ggaatatgtt
     8641 aagtgatgtt cgtctagaac ctcatgaaaa acgagaaatc atggacaagc ttgtcagcgg
     8701 ttatgatggg atcgttaaaa actttttaga agttgtttat gagtataacc gaatggatga
     8761 ccttttgttc atgatcgaag aatatgaacg tcgatatgat gaacatcaag ggttactatt
     8821 gggaagtgtc acaacagcag tcccactttc agacgaacaa cgaatacaat tagaaaagaa
     8881 tgttgcaaaa acaatggact atcaatcagt tgaattaaaa caaatcgttg attcttctat
     8941 tattggtggc gcgattgttg aagccaacca tcgagtaatc gacggaagca ttcgcacgca
     9001 attagaaaaa atgcgtaatc aattaaacag atagtacaaa gaggtaggtg aatcgaatgg
     9061 ccatcaaagc agaagaaatt agtgccttga ttaaagaaca aattgaaaat tatcaaaacg
     9121 tgctttcagt cgaagaaatc ggtaccgtaa cttatgtagg tgacgggatc gctcgtgcac
     9181 atggtttaga aaacgcgatg agtggtgagt tgcttgaatt ttcaaacggc tcatacggaa
     9241 tggcgcaaaa cttagagtca aatgatgtag gtatcattat ccttggcgat ttcgagtcca
     9301 ttcgtgaagg agataaagta aaacgaacag gtaagatcat ggaagttcca gttggagagg
     9361 ccttgatcgg tcgggtagtc aatccgctag gtcaaccaat cgacggacta ggtgaaatcg
     9421 ttactgacaa agctcgtcca gtagaagcga tggcaccagg tgttatgcaa cgtaaatctg
     9481 ttaacgaacc aatgcaaaca gggctaaaag cgatcgacgc ccttgtgcca atcggacgcg
     9541 gacaacgtga attagtcatc ggtgaccgta aaacagggaa aacttctatt gcgatcgata
     9601 cgatcatcaa ccaaaaaggt caagatatga tctgtatcta tgtagcaatc ggacaaaaag
     9661 attctacagt tcgtacacaa gttgaaacat tgaaaaaata tggcgcaatg gattacacaa
     9721 tcgttgtgaa tgccggtgcg tctcaaccag caccattgct ttatatcgca ccatatgctg
     9781 gtactgcaat gggtgaagaa ttcatgtaca acggtaaaca tgtattgatc atttttgatg
     9841 atctttcaaa acaagctgtt gcttatcgtg aactttcctt gctgcttcgc cgtccaccag
     9901 gtcgtgaagc ttatccaggg gatgttttct acttacactc acgcttattg gaacgtgcag
     9961 caaaattaag tgatgattta ggtggcggtt caatgactgc cttaccattt gttgaaacac
    10021 aagctggaga tatctctgct tatatcccaa caaacgttat ttcgatcact gatggacaaa
    10081 tcttcttaga aagcgacttg ttctacgcag gtactcgtcc agcggttgat gccggactat
    10141 ctgtatctcg tgtagggggt tctgcgcaaa tcaaagcaat gaaaaaagtt gctgggactt
    10201 tacgtctaga cttagcaagt taccgtgaat tagaagcatt tacacaattc ggttctgact
    10261 tggatgcagc aacacaagca aaactaaatc gtggacgccg tacagtagaa atcttgaaac
    10321 aaaaattgca tgcaccgcta gctgttgaaa aacaagtagt gattttgtat gctttgacac
    10381 atggattctt agatagtatc cctgtagaca gtattttaga cttcgaacat gaattattcg
    10441 aatatctgga taccaatcat tcagatatct ttgaaacaat ccgtacaaca aaagatcttc
    10501 cagaagaaga agcgttgaac agtgcgattc aggaatataa agacatgttc ttagctacaa
    10561 aaggaaataa ttcctctaca gaagataaat tgaaatccat tcaaaatgca tagtgaggtg
    10621 agatgaatgg gtgcttcatt aaatgaaatc aagacacgta tcgcttcaac gaaaaaaacg
    10681 agccaaatca cgcgggcaat gcagatggtg tctgcttcta agttgacaaa atctgaagct
    10741 tcttcacaga agtttcaggt ttatgcaaca aaagtaagag aaatcgttac gcatttgact
    10801 gctactcagt taaatgatat tgcctcagaa aatcctagag gggatatcaa ttacaacagc
    10861 atgttgctca gccgtcctgt taagaaaacg ggttatatcg tcatcactgc agatggcggt
    10921 ttagtcggtg gatataacag ctcgatattg aaacaaacga tgtctatttt agaagaagac
    10981 caccaatcac ccgatgatta cgtgatgatc gcaattggcg gaactggtgc agacttcttt
    11041 aaagcacgcg gtatcaatct agcatatgag ctgcgcaatc tatctgatca gccaagcttt
    11101 gatgaagtcc gcaaaatcgt aaatatggca acaactatgt accaaaacga agtattcgat
    11161 gaattatacg tatgttataa ccatcatatc aattcgctaa ctagtcagtt tcgtgtagaa
    11221 aaaatgctgc caatctcaga cttagatcca gaagaagcaa ctactttcga acaagaatat
    11281 atttttgaac cttcaaaaga agaaatcttg tctcagttat tgcctcagta tgctgaaagt
    11341 ttgatctacg gtgcgatcgt tgacgccaaa acagcagaac atgctgctgg tatgacagca
    11401 atgaaaacag caactgataa tgctgctaat atcattgatg agctgacggt ttcttacaac
    11461 cgtgcaagac aaggggctat tacccaagaa attaccgaaa ttgttgccgg agcttcggca
    11521 ctagaatagt attgagattg gaggaaaaaa gatgagttca ggcaagattg ttcaagtaat
    11581 cggtcccgtt gtcgacgtgg aattttcttt agaccaatcc ttaccagata tcaacaacgc
    11641 attagttgtt tataaaaatg acgaaaataa atcaaaagtt gttcttgaag cagcgttaga
    11701 attaggggac ggagtgatcc ggaccattgc gatggaatca acagatggtt tacaaagagg
    11761 aatggaagtc attgatacag gcaaagcaat ctctgttcct gtaggtaaag aaacattagg
    11821 tcgcgtattc aacgtactag gagatacgat cgatttagaa acacctttcc cagaagatgc
    11881 ggaaagaagc gaaattcata aaaaagcacc agcctttgac gaattaagta caagtacaga
    11941 aattttggaa acagggatca aagttatcga tttgcttgcc ccatatttaa aaggtgggaa
    12001 agtcggacta ttcggtggtg ccggtgttgg taaaaccgta ctgatccaag aactgatcca
    12061 taatatcgcc caagaacatg gtggtatttc tgtatttacc ggtgtaggtg aacgtactcg
    12121 tgaaggtaat gacttgtatt atgaaatgaa agattcagga gttatcgaaa aaacagccat
    12181 ggtgttcgga caaatgaacg aaccaccagg tgcacgtatg cgtgttgctt tgactggttt
    12241 gacgattgcg gaatatttcc gtgatgtaga aggtcaagat gtactgttgt ttatcgacaa
    12301 cattttccgt ttcactcaag ctggatctga agtatcagcc ttgttaggac ggatgccttc
    12361 tgcggttggt tatcaaccaa cattggcaac agaaatgggt caattgcaag aacgtatcac
    12421 atctacgaaa aaaggttcga tcacatcgat ccaagcaatc tatgtgccag ccgatgacta
    12481 cactgacccg gcgccggcaa cagcattcgc ccatttggat gcgacaacca acttggaacg
    12541 taaattaaca gaacaaggga tttatccagc ggtagatcca ttggcttctt cttcaagtgc
    12601 tttagcacct gaaatcgtgg gagaagaaca ttataaagta gcaacagaag tccaacacgt
    12661 attgcaacga tatcgtgaat tacaagatat cattgctatc ttaggtatgg atgaattatc
    12721 cgatcaagaa aaagtgttag tttctcgtgc ccgcagagtc caattcttct tgtcacaaaa
    12781 ctttaacgtg gctgaacaat ttactggtct tccaggttca tatgtccctg tagaagaaac
    12841 agtgaaagga ttccgcgaaa tcttggaagg caaatacgat gatcttcctg aagaagcttt
    12901 ccgaagtgtt ggccgaatcg aagacgtcgt agaaaaagcg aaaacactag gctactagaa
    12961 aggggtgccc catggatcaa tatttaacag taaatgtggt aactcctgcc ggtttggtct
    13021 atgatcacca tgcagctatc gtcgttgcac gtacgacagc tggtgagctt gggattttgc
    13081 ctaaacatgc accaatcatc gttccattga cgattgatga agttcgtgta aaacgaacag
    13141 attcagatac ccacgtcgat tggatcgctg ttaatggcgg aatcatggaa gttcgtgata
    13201 atgttgtttc aatcgttgct gatagtgcgg aacgtgaacg tgatatcgat gtatctcgtg
    13261 cggaacgtgc aaaacaacgc gcagaacgcc aaatcgaaga agcaaaagca aaacaagata
    13321 cgaacgaatt gaaacgggca actgttgcgt tgcaccgagc aatcaatcgt atcaaagtat
    13381 ctaagcactc ataaaatgag atgcggatgt ttatccgtgt ttaagaacag taaaaagagg
    13441 ttatgacaga agtggtcagc ttcaagacat aagaaggaat ttacgaaaat tgcttctcaa
    13501 atttttgtga aatctcagct tatttttcga agaagctact tctggaacac cgtatatcgg
    13561 aggttgtgaa atcagcgttt tgtcctgagt attagagaaa caaatggaaa atagttcctc
    13621 atattttgcc gttttttgag ctaataccga gggtcagatg attgaacacc gtttatttgg
    13681 aataagggac tgcgacaaga ct
//
LOCUS       DAYYEF010000066        13376 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000066 DAYYEF010000000
VERSION     DAYYEF010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.069"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(244..1092)
                     /locus_tag="ACHA1B_002348"
     CDS             complement(244..1092)
                     /locus_tag="ACHA1B_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFM8703087.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1256..2158
                     /gene="gnd"
                     /locus_tag="ACHA1B_002349"
     CDS             1256..2158
                     /gene="gnd"
                     /locus_tag="ACHA1B_002349"
                     /EC_number="1.1.1.343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydrogenase
                     (NAD(+)-dependent, decarboxylating)"
                     /protein_id="HFM8703088.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            2160..3161
                     /locus_tag="ACHA1B_002350"
     CDS             2160..3161
                     /locus_tag="ACHA1B_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="HFM8703089.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALIERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3158..3442
                     /locus_tag="ACHA1B_002351"
     CDS             3158..3442
                     /locus_tag="ACHA1B_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HFM8703090.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3475..4272
                     /locus_tag="ACHA1B_002352"
     CDS             3475..4272
                     /locus_tag="ACHA1B_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HFM8703091.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4286..5119
                     /locus_tag="ACHA1B_002353"
     CDS             4286..5119
                     /locus_tag="ACHA1B_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFM8703092.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5137..5994
                     /locus_tag="ACHA1B_002354"
     CDS             5137..5994
                     /locus_tag="ACHA1B_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFM8703093.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            6016..6525
                     /locus_tag="ACHA1B_002355"
     CDS             6016..6525
                     /locus_tag="ACHA1B_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HFM8703094.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6562..6963
                     /locus_tag="ACHA1B_002356"
     CDS             6562..6963
                     /locus_tag="ACHA1B_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703095.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7075..7428
                     /locus_tag="ACHA1B_002357"
     CDS             7075..7428
                     /locus_tag="ACHA1B_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703096.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7462..7905
                     /locus_tag="ACHA1B_002358"
     CDS             7462..7905
                     /locus_tag="ACHA1B_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM8703097.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7922..9007
                     /gene="uxuA"
                     /locus_tag="ACHA1B_002359"
     CDS             7922..9007
                     /gene="uxuA"
                     /locus_tag="ACHA1B_002359"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008927 - mannonate dehydratase activity
                     [Evidence IEA];
                     GO_process: GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HFM8703098.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            9000..9713
                     /locus_tag="ACHA1B_002360"
     CDS             9000..9713
                     /locus_tag="ACHA1B_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM8703099.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(9920..10069)
                     /locus_tag="ACHA1B_002361"
     CDS             complement(9920..10069)
                     /locus_tag="ACHA1B_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703100.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            10465..10665
                     /locus_tag="ACHA1B_002362"
     CDS             10465..10665
                     /locus_tag="ACHA1B_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA];
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HFM8703101.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            11233..11796
                     /locus_tag="ACHA1B_002363"
     CDS             11233..11796
                     /locus_tag="ACHA1B_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703102.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(11857..12222)
                     /locus_tag="ACHA1B_002364"
     CDS             complement(11857..12222)
                     /locus_tag="ACHA1B_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02328 family protein"
                     /protein_id="HFM8703103.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(12298..12543)
                     /locus_tag="ACHA1B_002365"
     CDS             complement(12298..12543)
                     /locus_tag="ACHA1B_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8703104.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(12613..12867)
                     /locus_tag="ACHA1B_002366"
     CDS             complement(12613..12867)
                     /locus_tag="ACHA1B_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703105.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(13031..13354)
                     /locus_tag="ACHA1B_002367"
     CDS             complement(13031..13354)
                     /locus_tag="ACHA1B_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703106.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
BASE COUNT         4573 a         2115 c         2791 g         3897 t
ORIGIN      
        1 aacaaaaata ataaaaaaaa gaaaagataa attttttact actgtatact aactttgtta
       61 tcgcatctaa caagtaactc gaataatacc aatacaacct tctccaaaga tgcgatgaca
      121 tacgttctaa cccaccgact attgatgttc tgtaccaccc ttgcagaacc aaaaaagcca
      181 ctaccaaata tttggtagtg gctttttttg ttttatggat ttttcgcttt ttctgttatg
      241 gtgctattct ttgatttcag aaatagtatg tcgaacttta gcgatagaac gacgtgattc
      301 tttttcgttg taaaacatca aaatcacata tagagagtcc aaaatgctta gttgagaaat
      361 acgggaagct aaagcttcag atcggaattc tgtttcttca gaaatagaaa taaaaacgac
      421 atcgccaagt ttagcaaggg aagaattagc ttggctagta ataacgattg tttttgctcc
      481 agtttttctt acggtttcag caatatggat tgtttctttt gattgccctg tgtgagaaat
      541 caaaacagca cagtcttttt ccgtcaataa agaagcttcc atcaattgaa tatggtaatc
      601 cgtgctgtga gaagttgcga taggggaacg caaaaattta tgataagcgt cagttgctac
      661 aatctctgaa ccgccaacac cgaaaaaata gacacgttta gattcattga taatagtagc
      721 cgcttttttt agatcctttt gttgtaacaa cttttttgtg tcatttaaag ttgaaatact
      781 agactcgaac accttttgcg ccatagtgag ctcagtatct gttttctgaa tattttcgtg
      841 gatagaaata gcagatagat cattttcttg gatcaacatg gccattttaa aatctttaaa
      901 tccattataa ccaagttttt ttgtaaattg aaaaaaagta gagtcagcaa tgcccagttc
      961 acttgctaaa ttgctaatag gactatgact tactttgctt ggattttcta aaatataatc
     1021 ggcgatagcc tgttcttttg ggctgaagtc gttgtacatt gttttgattt gtagtcttat
     1081 ggagacgctc atgagaattc ctcattttca taataagatt atcatttttt ccgttctcat
     1141 taatgttaaa gatacaagga gagtaggaaa aaatcaaaca aaaaatattt ttgtaaaatc
     1201 tatttacaaa aaaatttttt tgtataatga gggtataaga aatggaggcg ctatcatgga
     1261 aattggtgta attggtttgg gaaaaatggg attgaattta gctttaaact taaaagagca
     1321 ccatcacaaa gtacaaggac tcgacatttc aagtacagct gttagtcagg caagagaaaa
     1381 tgacattcct gcttatcaag agatctctga atttctagct acttttgagc agaaaaaaat
     1441 catctggtta atgcttcctg ctggagagat aaccgaaaac atgttaagaa aactttttcc
     1501 aaaactcgga ccaggagaca ttattattga aggcggaaac tcttattata aagattcaat
     1561 ccgtcgagca gaagagtttc agaaaaatga aatcggttac ttggattgtg ggacttctgg
     1621 aggaatcgaa ggagcacgac atcaagcctg cttaatgatt ggaggagata aagaaacttt
     1681 tctatccgtg gaacaattat tcaaagatgt agcaattgaa agaggatatc tgtatgctgg
     1741 tgcatccgga agcggacact tcttgaaaat gatccataat ggaatcgaat atggaatgat
     1801 gcaagcaatc ggtgaaggat tccaacttgt acaaaaaagt gagtatgctt ttgacttgga
     1861 acaagtcgca cgtgtttgga atcatggttc ggtgattcgc ggctggctga tggaaatcat
     1921 ggaagatcag ttaaacgaac atcccaattt aagtaattat cggggaatcg tttctgcatc
     1981 aggtgaagca aaatggacgg ttgaaacagc gctagaaatg gctgttccag ttccagtaat
     2041 tgcaactagt ttgttcatga ggaatctttc acaggaagaa gatagttttt cagcaaaagt
     2101 agtttcagca ctaagaaatg ggtttggcgg acatgaaata gttgaaaagg gtgagtaaaa
     2161 tgccagatta tcatatagca atcgttaatt ccagcagttt cggaagagtc tttccacacc
     2221 acttggaaag attaaagtca gttggagacg ttcatttctt tactgttgat caagagattc
     2281 caggaaaaga actagcggag ttacttaaag gattcaatat cattattgca agtgttacgc
     2341 cattttttcg acgagatttt tttgaaaaca aagatgaact gctattgatt tcccgacatg
     2401 gtattggtta caacaatatt gatttaaaag cagcaaaaga acaccagaca atcgtatcta
     2461 tcatacctgc tttaattgaa cgaaatgctg tagcagaaaa taatataact aatttgttgt
     2521 ccatgcttcg acgcacgaca caagcacaag caagagtcaa ggacgatcga tgggaagatc
     2581 gggcggagtt cgtcggtagg acgctgttta acaaaacagt tggtgtgatt ggtgcaggaa
     2641 ataccggaag cggagtaatc gaaattttgc gtaacggttt tcgctgtgat gttctagctt
     2701 atgatcctta caaatcagat ttatacatcg aaagctttgg tgcaaaaaaa gtagaacttc
     2761 aagaattact ggaacaatca gatatcattt gtttatgtgc gaatttgaca gaagagaact
     2821 atcacatgat ttctgataaa gaagtcgatc agatgaaaga aaatgtttat ctatctaata
     2881 gtgcaagagg cgctctagtt gatgaagaag cgatgattaa tggtctgaaa agcggaaaga
     2941 tcgcaggata tgccacagat gttttagaag aagaaccggg acgtcaagat catccgtatt
     3001 tagcgtttga acaagtagtg attacgccac atatatcggc ctacacaagg gaatgtttag
     3061 aagcaatggg tgaaaaatgt gtcagagatg tcgaacagat cagtcagcac cttcttcctg
     3121 aacgttctgt ccagacaaag agcaactata taaaaggatg atgaagaaaa tggtgaacgg
     3181 tttaaaagtg aaaacaggcc ctcaatttta tttatatgaa gaaggtggta tttcaaaagt
     3241 ttctgatctc ttgaaatcat acggcgcgaa aagagtactg gtcacccacg gaacggtatc
     3301 atgggaaaag gcgctaccta aattagtatt tttgaatgac gaaacgattc aattttttta
     3361 tcatcgttat tctggagaat gtagttatgc tgaagccaga cgaatagcta caatcatcaa
     3421 aaaaatgaaa tcgatttcgt agttggcgtt ggcggaggaa aactgaccga tctagtgggt
     3481 tatagtgcca atcttgcaag aatcgatttc ggagtcatcc ctactttagc tagtaattgt
     3541 gctccatgga cacctcttgc tgtcatgtat aaggagaatg gacaagcaga agggaaaaca
     3601 gaacactttt acagacaagc tgcttttttt ataacagatc cccaattagt gattgattcc
     3661 cctgttccat atttcattgc cgggttagca gatacactag caaaatggta tgaatctgag
     3721 ctcatcttag aacaagattt tttgcaagat gaatcatttt tgaagctagc acaagatact
     3781 gcgaagatct gcaaagaaga gattttgaat cattctgcta aagcaatcca agatatggca
     3841 caaagaaaac tgacatcgga gttcaaacag ctttcagaga ttatctttgc tgttgctggt
     3901 ttagttggag gattaggaga taaatacgca agaaatgcgg cagcacatgc tatgcatgac
     3961 gctatcagta aatatattcc ggaaagccat cgttttctac atggagaaaa agtagcgtat
     4021 gggattttct atcaactggc actagaaggt cgctgggaaa aaatagacga gttatatcct
     4081 ttgtatcggg aattagaact gccggtttct ctagaacaaa tgggattatt tccgaaagat
     4141 aaacagataa tagataaaat ggctgaattt attgattcga aagagaaagt gcatttgatt
     4201 cctatagagg taacacagaa atcactgata cagtcaatga tggaactgga aggttatatc
     4261 agaaagatct gaaggaggag gacacatgga aacattaagt gtagtacaaa gtttgttgat
     4321 tgctttatgg gtagccgcgg ttatgtcccg ctggttaggt ggaggagcca cgttgacctt
     4381 acgtttttct cctttgatga ctggattagt cgtcgggttg atcatggggg aagttgcaca
     4441 agcgatgatt gttacagccg ctttgcaaat gatttatatg ggggtttttt ctccaggagg
     4501 atcaatgcca gctgaaccat ctattgcagc agctatcgca gtaccagtcg cattattagg
     4561 ggatctgtcg ccagaagcag cgattgccgt tgcggtgcca gtcggattgc tcggaagtta
     4621 cttgtatcag tttcgttttt tcatcaatac ttttttaggt aaatatacag acaaagctgt
     4681 agaagatttg aatacaaaag ctatggcccg atcaattatt ctttatccaa cggttgcctc
     4741 atttttatta ttcgttccgc ttgttttcat tgctttatat ttaggggcgc cattgatcgc
     4801 tgatgtaatc aaagctttag agggaacagt cgttatccac attcttgaag tagtaggtgg
     4861 agggttagcg gcaatcggta tcgcgacaac tgtatacgtt atcggtcgaa aagattatct
     4921 ggtctttttc ttccttgctt attttatgag tgttgttttg aaatctttag atattacgat
     4981 ggttacttat gccatttttg ggattattat cgctttgatc tttgtccagt cgcaaaaagg
     5041 gaaacaagta cagcctgcca caagcaataa caattcagca tcttttgatg acgaagatga
     5101 ctatgatgac ggattttaat ttaggaggaa tgggaaatgg ctgaaataat ggataatcaa
     5161 acaggtgctc ctgaagaaat cacgaaaaaa gatgtaacaa aagcctatct gagatggcat
     5221 tttgcaaacg aaattcctca ctcttttgaa cgttacttgg cgccatcact actatacgga
     5281 atgatgccaa tcttgaaaaa actttataaa gatgaagact ctttaaaagc agcatataaa
     5341 cggcagttac tgttcttcaa cactcaatta agctggggtg gcggtgtgat tactggccta
     5401 atgtcttcta tggaacagca aagagcagaa gaagagtatg aagaaaaaga gatcttgatg
     5461 caggatgact tgatgtataa cacgaaagcg ggattgatgg gggcactagc aggaatcgga
     5521 gatgcaatcg attcaggaac cgtccaatat atttttatcg caatcgcggt accttgggca
     5581 caacagggaa gtcctttagg cgcacttttt ccttttatct gctttgggtt gtatcaggtt
     5641 ttactagggg tatttttcgc aagacaagct ttcactatgg gccgtaatgc tacaggccta
     5701 atgcaaaaca ctggtgttca gacagcgatt gaaatgctat cagttttagg gttgtttatg
     5761 atgggggtgc ttgcgggaaa ctatgtaaaa gtagaatctt cattgaaatt tgcgatatcc
     5821 ggacgtgagt ttgttatcca ggaaattctt gatcaaatcg tgccagggat attaccttta
     5881 gctgtcgtaa tgggtgtgta cttgttctat acgaaaaaag gattgaaagt cacacaagca
     5941 ttattatggc tgactggaat attaattgtg ctagcaggaa tcggtatttt ataaaaagaa
     6001 gggaacgtga ataagatggg tgtagtcaat ttagcgcgtg tggatgagcg tttgatccat
     6061 gggcaagtaa tggtaacgtt atctcaaaaa agtggagtga attccatttt tgttgtagac
     6121 gaagttgtag caaaagataa atttatgaga gatctttaca aaaatgcagg aagccgtaca
     6181 ggacaaaaaa caattgtcat tacaccagag aaagctaaat tctattggga tgaatatcaa
     6241 tttaaagaat acaattgtat tttgatcgca aaaacagtcc aaacgattta cgacttagta
     6301 aaacacggaa tccccatgga agaattgaat attggaggga ttgctcaaaa aaatcctgat
     6361 acagatcttt tagtgacgaa atctgtttat ttaaataaat cagatgctga aaaattgaaa
     6421 gaaatgaatg aacaatatgg cgtaaagaat atttattttc aagccactcc atctgcacct
     6481 aaaacaggat taaaagatgt attgaacaag tttgatttgt cataaacaaa tgcttagaaa
     6541 aaagataaag agggcgaaaa aatgaagaag aacgagctgt ttcgtgattg ggaatttcgt
     6601 tatcgctata tttaccgtaa gcgccgtaca aaaaagagta aacagcgttt tctttcagca
     6661 ttagtatcag atatttacag tatgagaaca gatgtgacag tcattgctta cgatacgcta
     6721 gcctaccgat caaaaaatat ttatgttgga gatatcgaaa aagcagagaa agttatctgt
     6781 acttattacg atacacccgt tcatgcatta ggaagttatt tcatgtttga ttggaaagac
     6841 caaaggaaaa aaacaatcta ctctatatta ttgtccttca ttttgttgtt cagtttaggt
     6901 tggtggggaa tgatgatata taacaaaaat cctcatcacg tattcgatct gctatccgta
     6961 taaacaggta tcactgtact agcatttggg agctactttt tcttattggg aaaagcagct
     7021 cgcggatggc ctagcagaca aacttttatt cgaaatactt catccatatt aacgatgcta
     7081 gaaatgatcc gtacgattga tgatccgagt gtagcgtatg cgtttgttga tgaaggctgt
     7141 tatggagaaa agggcttaga cagcgtgaga tcgggtatga aaaaagaggc tattcttttt
     7201 tatctagact ctgttggggc agatacaccg ctacagtttt cgggaaatta tttttcaaat
     7261 aaagaacagt ggctgaaaca agttgataag ttgaaagaaa aaaacgtcaa ttatattttt
     7321 agtgcaagaa aaaagcaagc gcagttcttc tatttgacca aaacagattt acgagggaaa
     7381 acatttaatt ggcaaaatgc caatcagatt attgctcttt ttcgataagt aaaaagtgca
     7441 aaacaaggag tgagaagact aatgttggaa atcatgatcg ttacacatgg taagttgagc
     7501 gaaggactga aagatgcggc ggaagtaatt gtcgggacat cgagccatat tgaaacaatg
     7561 tgcttagagt ctggggagga catccaaaca ttcggagaga aggtcaaaga aaaattaact
     7621 atgatcaaca cagcagaacc catgctagta tttgttgatc taattagcgc aagtccgtac
     7681 aatcaagcgc tcttggcagt caatgaactg actgaagaaa agaaagcagc cacttatgtc
     7741 atagggggcg tgaatctgcc aatgttgtta gaagcaatca atcatcagat gcttcacaca
     7801 ccgatagaag aagcggtgga acaaattgtc aaacaaggaa aagataattt aactgtttgg
     7861 catgcttcag cggaagaaaa aaaattagat gaggacgatt tttagaagga aggctgaaaa
     7921 gatgaagtgg ggatttagat ggtatggtga aaaaggggat tcgatcccat taaaatatgt
     7981 tcgccaaata ccgggaataa atgggataat tggaactttg ctgactaaaa tgcctggaga
     8041 tgtttgggag atttcagaaa ttgaggagtt gaaagcatct gttgagagcc aaggactgga
     8101 actgcttgga attgaaagtg tagcgatcca cgatgcaatc aaggcaggga cagatgaacg
     8161 agattactat attgataact atatacgaac aatcaaaaac ttgtctcgat gtggggttcg
     8221 attgatttgt tatagcttca aaccaatttt tggatgggcg aaaactgatt tgtttaatga
     8281 aaacaacgat ggaagctatt ctcttttata cgatcagaaa atcgtcgatc agatggagcc
     8341 aggagaaatg tatcaattga tacacagcca gtcaaaggga ttcaaattgc cgggttggga
     8401 agaagaacgg ttgaaaaaat tcgctcagct ggaaaaactg tatgaaggaa tgaccgaaga
     8461 agaattattt gaaaatctga cttatttttt agaaaaagtg attccagtgt gcgaaaaagc
     8521 agatgtaaaa atggctatcc atccagatga tccgccatgg gaactttttg gttttcctag
     8581 agtgacgaaa aatcttggcg acttgaagaa aattctaaat gcagtagatt ctccatataa
     8641 tggactaacg ctgtgcacag gatctttagg ggcaaatccg gaaaacgatt tagttgaaat
     8701 catccatgag gtaggttcgc gcatccattt tgtccacttc agaaacgtgg agtttttagg
     8761 agaaagaaag ttcaaagaaa cggcacatcc ctctacagaa ggctcccttg atatgtatca
     8821 tattatgaaa gcgttggtgc aagaagggtt cgacggtcct atacgccctg atcatggtag
     8881 aaccgtgtgg ggtgaagtgg ctatgcctgg atatggcctg tatgatcgtg caatgggact
     8941 cacttacatg caaggtctat atgaggcgat aagtaaggaa aaaccactgg gagagcatta
     9001 tgaataaaat caagctcttc atctttgata tggatggcct tttattagaa actggacgtt
     9061 tagcttatcg tgcttatgta aaatcagcac aaaagtatga ttatgaaatg cgtaaggaag
     9121 tctattattt actaactggc caaacagaaa tggcgataag agaacaaatg ggcattttgt
     9181 acggagaaga tgttccatat atcaaatggc gagaagcaat caatcaatat aaagaaaaaa
     9241 tcgtgaaaga agataagaga gtatatacga aaaaaggagc agaagaaatt ttatcttttg
     9301 caaaagaaag aggaatccat acaatcgtgg cttcgtctaa tacacgggta aaagtagaaa
     9361 tgtatttaaa aatggaaaat ctatatgcct tgtttgatca aatcatttca ggggatgatg
     9421 taaaaaaagg aaagccggaa ccagagatct ttttgaaagc ttgttcaaaa atgaatattc
     9481 ctccaagtga agcacttgta tttgaagact cgattgcagg gatcgaagca gcaaggcgag
     9541 cgggcatttt gtcttttctc atcaaagatc atttgatagg gttgcccgat cataatggga
     9601 agcataagtt gaaagtagat gtaagtttat atgaatccaa taaagcagac tatgaatttt
     9661 atgacctgca tcaagcaaaa cgatttttag aaagtaaagg gttgtatctc taataaagag
     9721 gactattttc tagtcctctt tatttattgt cctgcacgac tgagggaaca gatgaaaaag
     9781 aagtaatttt ttattttgaa gtatctacct tatttgtagt gaacaattta gaacaaacac
     9841 aaaacgcatc tactgttatc taccagtaga tgcgtttaaa gagaagaacg agaatcgtcc
     9901 atatgagggt ttccactcct tatgcagatt tttttaattc ttgcactgct tgttcgatcg
     9961 taacacctgt cgctacatga ttggtatttt ctttgtcaaa aacgacaaat agattcaaat
    10021 ctgtatccaa ggttactcga tattgtatat ctttgttata gaatgtcata gccattctcc
    10081 tttctttaaa tacttgctga aaggcaacga acgcgttgat aacgaaattc catttataag
    10141 tataccacca attgaaaggt tttcatagtt aagaaatttt aaagtcaaaa gttgcagata
    10201 aaagcaaata aacaagaaaa caaaaagtga atcaatcgcg gttattcaac tttttcttcg
    10261 attcgaagac aatagaagac aatgaatttt atatttcatt gcattatcct tgtgttatta
    10321 gaaaaagcat gatatattaa atgagtaatc tattttgaaa cgtaatttga gcgatatatc
    10381 tacatagata aaactccttt tgcctatcaa atatttattg caacgaaaaa acgtacattg
    10441 atacgtatca ggaggaattt atttatgaat aacggtacag taaaatggtt caacgcagac
    10501 aaaggttttg gctttatcac tggtgaagat ggaaatgatg tatttgcaca tttttcagct
    10561 atccaaggtg acggcttcaa aactttagaa gaaggccaag cagtgtctta cgatgttgaa
    10621 gatggtcaac gtggccctca agcaacaaac attgttaaag cttaataaaa attgactttt
    10681 aaccgtcttt tcgaaagaaa agacggtttt tttgtacgaa aaaattcatt ggtcgttgaa
    10741 tgggctgaat agtagtgtat aaaacaattt tgtggagcgt gaagctttta tggtagagga
    10801 aaatacgaat aaagtgatgt tgataaaaag attcctatct tgaatatgaa tcgagatgtc
    10861 ttgaaaatga atgagtttga ccaatcatta tcctatcgaa atttacagtt tcgttcgatt
    10921 ggtctgtcaa ttaatgaaaa agtaaaaaag aatatgttct aggaagaggg cggcacatct
    10981 aaatttttaa gtaacggaca gttcaaatat caagcattga aagaggctat cctactgttt
    11041 gaaggaatac gaatatataa aaacgacaaa gaggaaaaag tagttcatta aatcccttca
    11101 agtgatgaaa gaatgagatc taataaaacc tgatctttca tctgtttttt taataacgta
    11161 ataatttttt tattttttgt gctttcgccg ttattgtaga gtgatttagc attcttattt
    11221 ttaaaaataa ctgtgttata tattaaaaaa ggcataatag ttataagctt ttttaaagaa
    11281 tatttagaaa ttattaattt tcgtctgaaa acaaaaaaag aaagcgttat tattttagtc
    11341 tattttcagg gggggaacct tatgataaaa aaactatttt tactatcaat attaacgcta
    11401 gcaatggcag gttgttctga ctctggctta gcaactgaac tgatcacaaa atcaactgaa
    11461 gccacgacag aggagttaaa atgtggaaac gatcacagtg actacagagg cttaaatcga
    11521 cgatgcatgg gaatattagg cagaagcaat tgtaagcatc gatgtagtaa tcgaagaagg
    11581 tgtagaagaa gcaacagaaa aatcaaaaga aagatcaaaa gaagcaatct gtgctgtgca
    11641 tcgtatacag acgtcgaaga tgcggtactt ttaaaccacg tcaggagatg ttcatttatg
    11701 tctagggaag ttggcgatga accaaaacta gagtacgctt ttagttttgc acgtgaggat
    11761 gaagataacc ctaaaactta cgacatttta gcttgatcta agatggttaa agctttttaa
    11821 tgaagtaaga ggagatagaa ggcttttcta gttatattag gtaagataaa ttcctttttg
    11881 ctccaaattt gctaaacatt ctgctagata aacttcatcg tgttccggat aaatcggcac
    11941 gttgcgctct acagtaggta aatcaaaaaa tgcttcgcat gatttgccac gatacatagg
    12001 atttttccac tctggtgctg ggctgtaacc acgtttttcc atttcatcca tgacaagctg
    12061 atgatattgg aataatctat aaggagaata gtgaaaaaca taatccacag tagcatgttt
    12121 ctttccccag ccatttcctc ttaatgcaca gcattcccga tgttgtccta aaagctgttg
    12181 acgaggaagc tttgaaatca atttttcatg ccataatcgc atagaaatgt ctcctttata
    12241 tatagattgt taaccttaga cgttaaatga aaaaaccagc accaaggctg gaaaaaatca
    12301 cttcagtttg cttgctgttt ctgagcgacc aattaggtaa tcaacggaaa tatcgtaaaa
    12361 gtcagcgata tagattaatt caatgatgct tggaatttct tctccttctt cgtacttacg
    12421 atatttgaat aaaggaatac ttaacgcgct agaaacagct acttgagata aagatcggcc
    12481 agttcttaag aaattcagac gacaacgtaa agtatccagt aaaatagctt cttcgatact
    12541 catttaatca cctttcatta tagtagaata gttataatga ctatagaaag ctacacatgc
    12601 aatcaatagt actcaatgtt ttttatttaa acgtatcaaa taaagaatga cgatcaataa
    12661 agacaaaacc agtcctgata attcttctat aaaaacacta tcgggttcaa agtagttgta
    12721 attaaaaact ttccacataa agtagatagc cggaagagtc aaaatagcta aataaaaccg
    12781 ttctttgttc caattcataa gataaacaat acttgcgacc agtgcgaccg caggcaccca
    12841 aaacaaaact ctcaccaacg taatcatgta acggactcct caacgattca tataataaaa
    12901 gataacatgt tattgcatac atcacaaatg aaatgctagg aaaataaaag aagaatagat
    12961 caatgaaaaa tgaaaaagca gaacagtttt ctgctgataa gcaggaactg ttccgctgaa
    13021 tgtgtcttat ctatcgagaa aaaatcaatg gattgatatc taagtaattc aatacatata
    13081 aaaagaggac gatcgcattc actaaaaagg aaagaatgat gatcccatag cgaatggaaa
    13141 catatttaac aaatactttt gtttgaatac gggcatatct ttttccttta tagctgagca
    13201 tcatgacaag aagcaaaagg gtaatcacac cttgaaaaat cattccaata aacagaattc
    13261 ctgaggtttg ataatttaat tggagaaaat aagctgctgc cgcaactaaa tcgaataaaa
    13321 tcgcaataaa tggcaaaata atcactccta acattgagaa taaataaaag aataac
//
LOCUS       DAYYEF010000067        13083 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000067 DAYYEF010000000
VERSION     DAYYEF010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13083
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.070"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(78..2198)
                     /locus_tag="ACHA1B_002368"
     CDS             complement(78..2198)
                     /locus_tag="ACHA1B_002368"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFM8703107.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="ACHA1B_002369"
     CDS             2428..3606
                     /locus_tag="ACHA1B_002369"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HFM8703108.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="ACHA1B_002370"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="ACHA1B_002370"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003855 - 3-dehydroquinate dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HFM8703109.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="ACHA1B_002371"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="ACHA1B_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA];
                     GO_process: GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HFM8703110.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="ACHA1B_002372"
     CDS             complement(4959..6212)
                     /locus_tag="ACHA1B_002372"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HFM8703111.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="ACHA1B_002373"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="ACHA1B_002373"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016639 - oxidoreductase activity, acting
                     on the CH-NH2 group of donors, NAD or NADP as acceptor
                     [Evidence IEA];
                     GO_process: GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HFM8703112.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="ACHA1B_002374"
     CDS             7789..9135
                     /locus_tag="ACHA1B_002374"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HFM8703113.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9443..9829)
                     /locus_tag="ACHA1B_002375"
     CDS             complement(9443..9829)
                     /locus_tag="ACHA1B_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFM8703114.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
     gene            complement(10097..10246)
                     /locus_tag="ACHA1B_002376"
     CDS             complement(10097..10246)
                     /locus_tag="ACHA1B_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703115.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            10708..10920
                     /locus_tag="ACHA1B_002377"
     CDS             10708..10920
                     /locus_tag="ACHA1B_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703116.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(11198..12997)
                     /locus_tag="ACHA1B_002378"
     CDS             complement(11198..12997)
                     /locus_tag="ACHA1B_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HFM8703117.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         4290 a         2353 c         2577 g         3863 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatcgat
     9301 tgattgcctt gctctttagt ttgttttagg actttaagaa cagtgaggct gacttcgaag
     9361 gttaattctg tttttttgtt ttctagaatc agtaagcaaa aaagcactca cttcgagtgc
     9421 ttttttgcga tatattctta gcttaagata ggcctaattt ttcttttaca gatgagggta
     9481 ccttatcgct ggtaattact tttttctcta tgatccgctt ttcgcttgct ttcaactgca
     9541 agatcgttcc ttcggtgtaa gcagaaccat tggcagagtc accagaagta atgacatcga
     9601 aatctaactg tcttttttca ccgttttcag cataagcatc tacgttgtat ttaaaacctc
     9661 ttccaattac ttccccatta tctgctttga tatcagtttc tgcaggcatt ggagctttga
     9721 ctaccgcata ataatcttta cctacataag tagactgata gtagtcccaa cctttccatc
     9781 ctataaaagc aatcaatatg ataacgatca accctaaaat ttttttcatg aaagatctcc
     9841 ttttttattt ttattatatt aaatattata cagataataa cggaatatta tcatcgaaac
     9901 agctaacaaa attgtcataa aaaacgagat ggttgatatt agaacttgtg tttttgttta
     9961 ggtctagaga taaagagaga caatttccaa atatatgtaa tgaatacaaa aagacgtttg
    10021 tcgcggatta ccgttacaaa cgtcttttat tgattttccg agatctcatc agtcgccatt
    10081 tggaatggtt cactccttat ctagattcgt ttaatgctcg gactgcttgt tcgattgtaa
    10141 taccaaacgc aacgttattt tcgttttgtg catcaatcgc cataaaacgg ttagaagttg
    10201 tatcaaaagc tacgcggtat tgcatatttg tttttgtaaa cgtcataaaa ttcatctcct
    10261 ttgtaatgta atttagttct tgaaagtttc ctttaaactt tcgaacttat accaagttta
    10321 gcatcgtacg ttttttgatg caattaaaaa gcatttatca ttttccttat ttattttttc
    10381 ttaaatggtt tagctatttt cttttaatcc gataagtagc ccaatcatca aggttacaaa
    10441 tactattgct tgaatataaa tcatatgctc acctctttat aaataactta gcaatataaa
    10501 gaaaaaaacg cacgaacaac ataggaatat aaacaaacgt ttttgtcaca acgtctaaga
    10561 tcgtgttaaa aaatagttat ctaaaaagca gaaagatact caaaataaaa aataaaaaaa
    10621 tgaataaaaa cgttttcaaa tacaaggtaa tttgttatta taaaataaag aaaaaacaaa
    10681 ataaaaataa agaaaagagg gaatgaaatg gtaaaagcag aagtaggaag atcttatata
    10741 tgcaaaccga tcggagtatc tcatgaacta atcggctgta ttgaacgtac atatatcaac
    10801 acggctgtcg tgtatgttga aagttatgac caacgagact atcaacttat caatgaaagc
    10861 aagtatcgca tgctcgtaaa attctgtgat attagcgcac ctactgaatt ggtttcttaa
    10921 acagtatttt tgagaattcg caagaactcc cttataatat aaataaagac agaagggagc
    10981 gagaagatat gccaaaaaga aaaagttcag ggaaaatggg aattattctt gcagtgatct
    11041 ctgcaattcc tgctatttta gctattgttc gtgcgatgaa ggaatcaaga gaaagttaag
    11101 cacacattat gagcgtcaaa caaaaaacgc atatacctgc ggtggcaggt tatgcgtttt
    11161 ttgttgtata aagacttttt tcattaacga tttttgatta gccgactccc aaaacaaaat
    11221 ttagcagttt atctgaataa gtgatttctt catctgtttg tttcacactt tcatttagta
    11281 gtcccatctc atcggttatg ataccatcca caccataaaa catcatgcga ctcatggcat
    11341 ctgaatcgtt gattgtccat acatatactt cttttccgtc ttggtgggca gaattaatga
    11401 agttacggtt gatcgtacta tattccattg tcagaaaatc agcaggcgtc acagggggcc
    11461 caacaatatt gaaaggtaag atgtagccca cataaaagtt tggttctgct tcttttaaat
    11521 ctgaaacggt ttggtacgtc aaactttgca aaatatgatg gttctctaag ataactttgc
    11581 ggtatttatg gacaaatcgt tcgacaaggt catccgaatc ttttttagag gtcttgatct
    11641 caataagtaa tttttggttt agcttatgtg ctttttccaa ataagaatca aaagaacaaa
    11701 caggggcttg cactccgttt tcagtaactg taagatttgt caattctttc aatgtaagat
    11761 cctgtggtgt tccatttacc cctgttaagt gacgaagatt tgcatcatgc atcactacga
    11821 aatgaccatc ttttgtttcc tgaacatcca tctctacata atcaggatga tagtctctgc
    11881 ttgttttttc aagtgcttct aaagtatttt gcgccccatt ttgggtactc acacctctgt
    11941 gagagacagt cactggtttt gtctgaacag ctgaagtcag ataatccata ttgtaaagac
    12001 agacgccaat accgaaaaaa actgcaaaaa gagtcaaacc agtgtttttc agcgcagaga
    12061 aacgcaagtt gggggcttgt gggataaacc acttagggat ctcaggcaag aagccttcgt
    12121 catccatgaa atcaacaatg atataaaaaa tccctacggt agacatcacg atattgaata
    12181 ataaaatccc ttgtaaaagc gtcatagcaa acacagcgct gatcaatgca tagtctggga
    12241 aaaattgttc aaccatactt tgtgccaaaa taacaacgat atatcctaaa gaagaaagga
    12301 gtaaaatcgt accgccaatc acaataaatt ggcccgtgat ggccaaaaga cgcgatttgg
    12361 tcaatgacca gctttcccga atggctgctc gaaaagaacg atctcgtaga atcatttccg
    12421 gtaaagcaaa aatcagtcga atcccaatat agccaaggaa aatataaacg agtaaaaagg
    12481 aactgacgat gatccaacga ttagcaaaaa taaaatccat aatgaaagcg gggattttta
    12541 tttttgacag tagatcagaa ttaaaactta atccgctgat cggtagaatc aataaaaaat
    12601 aagcaaggaa aaacaaaaaa gtaatgggtc tcactttctt cagctgaagt atcgtcaagt
    12661 gtaagagttg cttcaaagag attggttctt tctttttaat aaaaaaaaca ctcatcaaaa
    12721 gaaaagtaaa ttcgaaataa actaacagta aaatcgtcat caaaactacg attaacgaga
    12781 gtagaacccc aggatgttga gaaaaaattg aaggaatatt gtcataagac aaatagtcaa
    12841 ttgcccctcg gtgtaaaata aaacgggtcg tactgctcaa taagggtaaa caaataaata
    12901 aaataaagcc atgcatcagc aagacatcac ggaaataagc ttgtgttcct tttaaaaagt
    12961 cccaagcatt acctaagcta cgtttcaaat aattcatcct atcacctgct cttcacattg
    13021 tagcgcaaat ctaatgaaaa aggaaagggt gcagtgtgtt ttgcagaccc tttcccagat
    13081 tta
//
LOCUS       DAYYEF010000068        12775 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000068 DAYYEF010000000
VERSION     DAYYEF010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.071"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(143..457)
                     /locus_tag="ACHA1B_002379"
     CDS             complement(143..457)
                     /locus_tag="ACHA1B_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703118.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
     gene            743..982
                     /locus_tag="ACHA1B_002380"
     CDS             743..982
                     /locus_tag="ACHA1B_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703119.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(1344..1604)
                     /locus_tag="ACHA1B_002381"
     CDS             complement(1344..1604)
                     /locus_tag="ACHA1B_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703120.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1789..2286)
                     /locus_tag="ACHA1B_002382"
     CDS             complement(1789..2286)
                     /locus_tag="ACHA1B_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_function: GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HFM8703121.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(2416..3126)
                     /gene="budA"
                     /locus_tag="ACHA1B_002383"
     CDS             complement(2416..3126)
                     /gene="budA"
                     /locus_tag="ACHA1B_002383"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047605 - acetolactate decarboxylase
                     activity [Evidence IEA];
                     GO_process: GO:0045151 - acetoin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HFM8703122.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(3139..4803)
                     /gene="alsS"
                     /locus_tag="ACHA1B_002384"
     CDS             complement(3139..4803)
                     /gene="alsS"
                     /locus_tag="ACHA1B_002384"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0003984 - acetolactate synthase activity
                     [Evidence IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0034077 - butanediol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HFM8703123.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(5009..5684)
                     /locus_tag="ACHA1B_002385"
                     /pseudo
     CDS             complement(5009..5684)
                     /locus_tag="ACHA1B_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            complement(5694..6563)
                     /locus_tag="ACHA1B_002386"
     CDS             complement(5694..6563)
                     /locus_tag="ACHA1B_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8703124.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            complement(6574..7470)
                     /locus_tag="ACHA1B_002387"
     CDS             complement(6574..7470)
                     /locus_tag="ACHA1B_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HFM8703125.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            complement(7523..8782)
                     /locus_tag="ACHA1B_002388"
     CDS             complement(7523..8782)
                     /locus_tag="ACHA1B_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HFM8703126.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            complement(8811..9125)
                     /locus_tag="ACHA1B_002389"
                     /pseudo
     CDS             complement(8811..9125)
                     /locus_tag="ACHA1B_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345994.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
     gene            9182..9328
                     /locus_tag="ACHA1B_002390"
                     /pseudo
     CDS             9182..9328
                     /locus_tag="ACHA1B_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332517.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane glutamate
                     endopeptidase"
     gene            complement(9416..9658)
                     /locus_tag="ACHA1B_002391"
     CDS             complement(9416..9658)
                     /locus_tag="ACHA1B_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HFM8703127.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(10111..11289)
                     /locus_tag="ACHA1B_002392"
     CDS             complement(10111..11289)
                     /locus_tag="ACHA1B_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8703128.1"
                     /translation="MENMSRFKKHISATGKITWYFQAFRTTRRGFNSKREAQLAYLEM
                     ERQHRNQKKRIASNDKFSVVSQKWFEYYRSLNEQKIATYDKREEQVEILNRWIGDEKL
                     SSLSSEELQKFLFILKEKGINGVDVGYAKNSLQSLVQVLNMIFKYCMKKNLTNENPMK
                     FVKMPKYQLTVKDLKESVNSLEDKFLTVDELRTFLNYGIIYEELPMSVLFHVLFYTGC
                     RVSEALALQPQDIDFERNEILFYKQTAVKGKSKDFRIETTKTVSSARRVPVTPLVMEK
                     LQELIDVLNKTKRNSNFVVDETYLFVYLDPGKRGVPYRREYVNDHVKRCVERCGINKD
                     FHTHLARHTMASLVAEYCSWDVLKDRLGHTDSTTSKIYRHLTSNERKKPLLAFDSLEN
                     "
     gene            complement(11392..11685)
                     /locus_tag="ACHA1B_002393"
     CDS             complement(11392..11685)
                     /locus_tag="ACHA1B_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703129.1"
                     /translation="MSKNNNKSNTSENYLFHPENIDKMKGINQLPLVLTNKDLKEQLQ
                     ISDSTLNRLIKLEDFPCCWFGIRGHYLRDDILEWVKKGKEEYFCDQFRLLRLS"
     gene            complement(12040..12285)
                     /locus_tag="ACHA1B_002394"
     CDS             complement(12040..12285)
                     /locus_tag="ACHA1B_002394"
                     /inference="COORDINATES: protein motif:HMM:NF024059.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703130.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMLSQLEIKLIEAILKFKIN"
     gene            complement(12279..12680)
                     /locus_tag="ACHA1B_002395"
     CDS             complement(12279..12680)
                     /locus_tag="ACHA1B_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HFM8703131.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
BASE COUNT         4047 a         2550 c         1866 g         4312 t
ORIGIN      
        1 taaactctag agaaattaat tcatcctaac ataaaataat tgttcactca aaagtttttc
       61 tagaacaatt aaaacagcag gcttcacatt cgctatacat ttgtaagaag taataattcc
      121 tgtactaaaa ggcataattg ctttaattat tttttgactt ctcttcaaac acaagaagta
      181 gttgtgtaat aattgcagaa ataaggattc caataataga tataaaattt gacatggaaa
      241 cgtctataac attaaaagaa taaagtgttg aagaaagtaa actgattgaa ataacccctc
      301 cgtaaaaaat agtctgtgaa tatacccact ttttttcaga agacgtactt cgtttggttc
      361 taaaacctat ccctgcattt ctactcttat caaaaaacca aatatttaga agtaataata
      421 ttgctattat taagataaaa ttactgtaaa aatccaaaag ctatcctcct agcaactatt
      481 taaataccca aaaaaattac ctctagataa tatcatacct acgttttcac ttataaattt
      541 tttcataaaa aaagcgttta gaggcataat cgttaataca gatggtaacc aatgtatctg
      601 gtttgaactg ggatatcacc ctctccatat atgtattact aagactaata gatactataa
      661 aagacttgat agttttgcat tgattttgcc taatactgag cataggtgta tgctaaacga
      721 tactataagg agtgtgtaca taatgaaaag aattctgttt atcagtttat caaatttatt
      781 gttacttact gcttgtggga cttctgcatc aaagaacata ccttcagata cgcaaatttc
      841 gaatagtatc gattcaacaa tttctacaaa tgagaaaaat tctccggtag aaacttccga
      901 tataaaagtt tctacctctg caaaaaacag ggtaaagaaa ctgtcagcac gtctccttta
      961 tttcaaacaa actctgaatt agcttcttca tcttcttcag caaataatga tgatagtttc
     1021 gcgtttactc ctaactaaat gcaaccttta caaatgcttt acgataacaa gcctgagcta
     1081 aatgatcctg atatcagttt tgcatttttt gaaatgattg gatcggatga tctttttaaa
     1141 actactagtt tgtctatccg aaaataggac agttctggca gtataggttt ttatcgagtt
     1201 tctccaccag gcctcgttac agagacagat tctctaggcg aaccttttga ataaatcaaa
     1261 aatcatgaac aatcactgcc aactaaataa agtgccttca aaagcttggt cttctcgctt
     1321 ttgaaggcac tttatttaaa tctttatgaa actaaagtat gttcatattt gttgctatag
     1381 ttatatagat attctgttgt ttccaactca taaacgtgag tatattttgc cactactttt
     1441 ccgcattttt ctaatatttc attgcgatcg acgtcatgat attcgtctac gcagatcaca
     1501 acacaatttt ctaatttact gattacttct ccaatcactt tttgtttcaa gccaataggt
     1561 tggcaaatat atttttttcc taaaatgata gtttcgttat tcatatttca tccatcctta
     1621 atgttttttc attatttaaa atgataataa cattaaaata tgattatgaa aatcaataac
     1681 acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag aaatgcccac tgtctttccg
     1741 gctcttttta ttcttgattt ctcttctttt ttgtttcaat agacgatttt agttattaat
     1801 aaatgaaaaa gcatttatat taaaatttgc taataaaaga tctacatatt tttctagaaa
     1861 tgcttgatcg atttcatcat accctttcgt tactccgcaa tcgatatcta aaacaccgat
     1921 taaattacct tcttttacca ttggcactac gatttctgat tgtgcggctg aatcgcagga
     1981 aatgtaattt gcatgggttt tgacatcatc aacgatcaat gtttcttgtt tttcagctga
     2041 ttctccacaa actccttttc ccatcttgat acgtgtgcaa gaaactcgcc cttggaacgg
     2101 tcctaaaatc aattcattac catcgaataa ataatatcct gcaaagacag tctcaggcaa
     2161 agtctcattc aacaatgcag atgaatttgc taaatttgct aaccagttat cttctgcttc
     2221 taataatcct tgttgctgta ataataaaat ttcgtatgca tcttttttct gtttttctgt
     2281 ccacatgata aaaaccgctc ctttttgatc tatggagaag attatagctc agtttttttg
     2341 taaacgctag gttttctcct caaaaaaacg agatacgtca ggttaatcac cttgaacgca
     2401 tctcgctgtc tttttctatt ctgcttgttg gatttctgct gctaaatcag cataatcaat
     2461 cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc tgtacaaggg acgagatgcg
     2521 gctaatctca acttttcctt cagccacttc aaaatccatt acatgtccgc caaatgtatg
     2581 tgtatcatcg ataaaatgca ggtgaaatcc cgctgcagca actccttgga ataattcagg
     2641 cgtaaagaac ccgactaatg ttccttggac attgctttgt tggaattctg gttgagactc
     2701 tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc ggcatgatac ggatgtgcat
     2761 atttttgaat aatccagtta tcttcactgc caaaaatagg ttttccccgg cttctcttac
     2821 taatatgtct tttttcaatt gttctccatc tgcagttttt gagacagaaa aactagtatc
     2881 tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca cttccatcta attgggcaac
     2941 tgagccatct gatcttcctt gataagctac gccatctaaa aagatgactt caccatcaag
     3001 cccatgcaat gttcccaatc ccagagttcc tttttctaat atatgagcaa tcgtttctgt
     3061 tccatccatc aagccggcca tcaaagctcc taatgtcccg tgctggtata agattttttc
     3121 agtcatgtcg acacttcctt aatagaattg atctggtaag attgtttctc ccaatttctc
     3181 attatcacgg taatcaatcg gaatatcaat aattacgggt ccttctgtcg caaatccttc
     3241 ttctaaagct ttttctaatt cctctacact tgtagctcgg attcctttag cgccaaaagc
     3301 ttctgcatat ttcacaaaat caactggacc aaagtctaca cctgacgccc gctgatattt
     3361 cattttttct tggaactcta ccatattgta gtgtccatca ttccaaatca aatgaacgat
     3421 attcaatttt ttacgtaccg ccgtttctaa atcctgggca gagaataaaa atcccccatc
     3481 gccggaaact gatacgatct gtgtatttgg acgcaccaat gcagcagaaa tcgcccatgg
     3541 caatgcaaca ccaagcgttt gcataccatt actgaataac aaatgacgag gttcataact
     3601 tctaaagtgg cgtgccatcc aaatataatg actacctaca tctacggtaa cagtcatatc
     3661 atctgttact tttgactgaa gcgtgttaat aacttctaaa ggatgcaaga tacctgcttc
     3721 tccttttgat tgaacaatgt cccgctccgt taattttgct tgaagagatg ctaaatattc
     3781 ttttgcatct tctgacactt gttgaggctc taatgaacct gtcaataaat caagagtggc
     3841 tgagatatca ccgatcaatt ctctttcagg ctgcataaaa ggatcgattt cagctggcgc
     3901 ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc cagtttcttg cttcatattc
     3961 gattggatca tagccaattg caataactag atcacttcgt ttcaaaagca tatctcctgg
     4021 ttggtttcta aataaaccca cacgaccaaa gaaatgcgct tctaattcac gtgagatcac
     4081 tccagctgct tggaatgtct ctacaacagg caatgctgtc ttttcaacta attgcctgat
     4141 ggctaacgtt tctttttcac ttgatcctcg catacctact aatagtaccg gtagttttgc
     4201 ttctctaatg cgttcagcta ggtaacggat atcatctgca gaagcagaac ctaatttagg
     4261 atcgctcaat ggcttgatga cattaccttg gacaggtgca tccactacat cttgcgggat
     4321 actgataaag ctcgcgcctt tttttgaact cttagccata cgataagcat tggcaatcac
     4381 ttctgaaatt gtttctggat cttggatttc tgcactgtat tttgtgattg gctggaacag
     4441 tgctgcatta tccatgcttt gatgggtcaa cttcaataga tcgcttcgtt ttacttgtcc
     4501 ggcaattgct aaaactgggt caccttctgc tgtcgctgtt accaaacctg tagctaagtt
     4561 actagcacca ggaccacttg ttgcgataac tactcctggc tctcctgtaa tacgtccgat
     4621 tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc acgattaatt caggaccttg
     4681 atcctctaat tcattaaata caccatcgat ttttgcacct ggtataccga atacataatc
     4741 aacatgatga ttaatcaaac tttctactac agatttcgaa ccttgtttca ttttttcagc
     4801 cattgaacat cgtccttttt atgctttatt tttaattatt agttagaaat aatcacaaat
     4861 aagtgataca gtttctaaac ctgtttcatt caaaagtata gcatgtttta tttcatttgt
     4921 ttagccatat gtttcaaaaa atgaaaaaga atgacagttt ttacataaaa aactgtcatt
     4981 cttaattgaa agtttcaatt tataaagtct acagatccat agttctcatc aatttacgat
     5041 tgttgaagta aatcaaacca aatacgatag aaggacctag tagaatacac cattggggct
     5101 ttacgaaaaa gaagagaaac aaacttgtca atagtaaaaa atctagtaaa ctcacatacc
     5161 attttttcaa cgtatagtag aacgctatcc gtagaacttg atttggtttc gacgctggat
     5221 ttctcacctg aaaataccag cagttgatgc taaaggaaac tgataaacaa gcaagtaaaa
     5281 caagcaagta aaacaaacaa cggaatcaac cattttccat aagaaaaacg tataaaaaag
     5341 aaacaatcaa aaatcattat cacactaact atccaagcaa atagccaata aaaaaatccc
     5401 tttagccaaa attggcgaaa cgtctttatg aacaaacgta ctggtgaaaa acttttttct
     5461 tttgctaatt cttctgtcat acctatcatc acgatgcaac ctggaccaat aaaaagtaaa
     5521 gaaaaaataa aggaaaagac attccttcca tctatcgaca aaaggaacgc agctgctata
     5581 tacaagatat tgacacacca aaaacaaagg ctacttgcca atgattgata caaccaataa
     5641 aagaattcca tataaacatt tttgtcaaaa cgctgctctt tcataatcac ctcctattcc
     5701 ttcattcctg atgaagcgat cccttctaca aaatattttt gcatcgctaa aaatataaaa
     5761 gcaacaggaa gaacagaaac aactgaggca gccatgatta atgcgtactc tgcatcaaat
     5821 agcccaataa acattttcaa ccctaactgg attgttttat tttccgtaga agacaaataa
     5881 atgaatggcc ccatataatc gttccatgta ttaacgaatg tgatgatcgt caaactggca
     5941 atcgccggtt ttgtaagagg taaaatgatc ttgcgataga tttcccactc tgataagcca
     6001 tcgatccgcg cactctcaca taaagaatct gggatactac tgtaatattg cttcaacaag
     6061 aacacaccaa aagcattgaa cgcttgtaat agcaccaacg accacaacgt atctgttaaa
     6121 cccacttttc tcatcataat gaactgcggg atcatataag actgccaagg gacagcaatc
     6181 gtgccgatat atgctaaaaa taaaatatcg cgccctttaa aatttagttc agaaaacccg
     6241 taaacagcaa aactagaagt aaacaactga atcaacgtga tcacaacgct taaaaaagct
     6301 gtattcttaa aaaatgtcac taaaggaata cgagaccaaa taaccagata attctctaaa
     6361 tgccaagttt tagggatcca ttgaatcgga atcgttaaca cttcattatt tgctttgaat
     6421 gaagcagaaa ccatccataa aaaaggaatg atcgtcaata aagctaatac aatcagcaga
     6481 atcataccca accattgaat aaagggcatg ttttttgaac gaatttttgc tttttttctt
     6541 tcatttcgaa cactctcttc catatcacac ctcctaagta cgacgcttat tccaagaaaa
     6601 ttgaacaacc gtaacgccca aaacaattac gaacaaaaca agtgaaatag ctgaagcata
     6661 accaaaatca aattttttga atgcttcatt gtagatttgg taaaccagca catttgtcgc
     6721 tcgaccaggg ccgccatccg tcatcacttg cacaaggtca aacaccttga aacaattgat
     6781 gacaagcatg atcgttacaa agaaggttgt tggtctcaac gaaggtaatg tcacattcaa
     6841 aaattgtttc caacggtttg ctccatctag cgaagacgct tcatatagtt ctttttggat
     6901 actttgtagt cctgcaaggt atagaatcat gtaataaccc atccctcgcc aaatactgac
     6961 aattacaatt gcccaaagcg cccaatttga acttgaagtc caacctggag gatgttcaat
     7021 aaatcgtctt aaaaagatat taataggtcc cactgttgga tgaaacaaca tattccaaac
     7081 aacagcaatt gctactaagg aagtaacata cggaaagaaa aatatcgtac gaaaaagctt
     7141 catccctcta attttctgat ttagtagtaa agctagccct aacgaacaaa caagtgtgcc
     7201 aggcactaca gcagcggtat ataaaaaagt atttttcaaa gaaatccaaa atgtctcatc
     7261 gttggccatt ttacgaaagt tatctagtcc agcaaattct ggcgttgaaa aagaatccca
     7321 tttcataaat gctagtacaa gcgaaaacag gattggtatt aatgtaaaaa cgaaaaaacc
     7381 aatgaaattc ggggcgataa acgaataagc gatccacgtt cgttttctac gcaaatgatt
     7441 tgtagctttc ttatttatac tattctccat ttcgatgacg aaaccaagag tgttttatct
     7501 cttggcttct ctcctttcat gattattctt tttccgcagc tacacgtttc tccatattta
     7561 ccgttccttt ttccggcgtt tcatctccaa ccaaaactaa gtcatattct tcttgtaaaa
     7621 tcttatcgat tgcaggccca tacgtatcaa tcggaaattc aagtttgatt tcatcaggag
     7681 aaaaagcttt tttagaaatt tcatccgttg gcattccagc gagattaaaa taaagctgat
     7741 caatctcatc cgtacgatat gaaggaacta ctcctactcc tgctaatact tttgctcctt
     7801 cttcactggc tgcaaattca ataaattctt gcgccgcttt ttgtttcttt gagtttttat
     7861 tgacagcaaa tgctgttggt gagccaaacg tcgtgaccga ttctcctttt ttcttctgag
     7921 gaatagctgt aattccccat tctacttctg tcttacttgc ttctttgttt gcgagtatgc
     7981 cagccatata ccaagttccc atgtacatca ttgctgcttt ttgttcttca aattgagact
     8041 gataggttac tttcgttgat ttagccgtgc caaaatccat ctgcgcgcct tctttttgca
     8101 tcctcaatgc tcgatcataa taatcagtca tatattgata atctggttca acaagattcg
     8161 cctcgttttg agcagctgca atagcttgga ttgtcgaacg ccagatatgt tgatatgctc
     8221 cgtaaacttg tccgtcattt ttactaagtt tttttgctaa atcttcatat tcgtcccaag
     8281 ttagattttt tggatattcg attcctgcat catcaaacat tttcttattg taatatagta
     8341 cccaaaagtc cgttcgatat ggcaatgcat atgtttttcc atcgatatca tacatttcat
     8401 atgtttcttc agcagcatca gtgtctaatt ctctaattcg ttctgtttga tcgactaact
     8461 gatctcgtaa agcataattt gaatacgaca aaagattttt catcgtcaat acatctgtcg
     8521 tgtctccaga agaaagcatc gtggtgagtt tcgtatcata atcatctgaa gcaatatcta
     8581 ctgctttcac tttgattccc gttttctttt cgaatgcttc aaagagcgct ttgaattcag
     8641 gtgttgtttc ataattccat gtcgaaacgg taatttcatt tgctgattct tcactactgt
     8701 cttcttgatt accacaagca ccaaatacga gtgacattcc taaaactatt gatccaatca
     8761 tcattttttt ccatcgcttc attatatgaa tcctcctctt ctcttataca tcaccagtaa
     8821 cagtaccatg ttttagctag acgagtgatt ccttctacat aaaagtaatc gccccagatc
     8881 acacattcat ctacaccttt taagctgttt ttatcataaa cggcatggag aagcagaccg
     8941 tttgatccgt taactcgttt cgttgtatag tttttctgta attcttccaa gattttgatt
     9001 gctatctctt cgtaatcgaa atgacgagga tctgaaacag gcagttgttt ggaaagttct
     9061 agcaatccac atgccgctat agctgctgca gaactatctt tttcctcttt gctatcttct
     9121 ttgaatctaa ttttaggagg tacgttttgg tatttattcg tacaaataaa agagaattat
     9181 ctttattcat gtaacgcatc caattgattt tttcatgtac gctcctggaa cgattttact
     9241 gacgattgct tatttaactg cgaatcgctc attagctttt atcatagcta tccatatttt
     9301 gaataacgtt cttggctttg tattatagat acagatgaca aaaaaagttc aagtatgcgg
     9361 tgtagaacca atatcgcata cttgaacttt tttcaatgag tataaattaa aacttctaat
     9421 tttcaattcc catcatctga tatgcccgac cgtctgaact tcttttgaaa aagccaaatg
     9481 tgattagata acgtctttgt tcgacataat cgccactaga aaatacgttc agcagtatcg
     9541 aattaacctc tgtttctgta taagtcactc catggtcaaa gcgtttcaag acttctttca
     9601 ataggatgtt tttctttttt gttgaacttg gtacttgttt tacttttcca tcattcatga
     9661 atgtgtctca aactttcatt ttttcttgct ccgtataagt ataaaccatc ttctttctcc
     9721 ttttgattct aagaatactc catttatgtt agaatattct ggatttttta ttaaagcggt
     9781 tactcttaag aaagatatta tcatagtgct ctttttttta ctactactta taggtagatt
     9841 tattctaatc cattattctc ccctaccaat aattaaagaa aaaaactgga tcagggtgtt
     9901 caaattacat gctaagaaaa aagaaccctt gaataccaag ggttctttct cagtctgata
     9961 acaatgatta acgacggatt tctttgatac ttgtgaaaag tcatgaaagt attgatataa
    10021 aagttttaaa aaaaaattga ctacactttg actaaagtat agtaaaaaca cctattttag
    10081 aatctaaaat atctgcactt ctaccaaaaa ctagttttct aatgaatcaa aagcaagtaa
    10141 aggttttttt ctttcatttg atgttaaatg ccgatatatt tttgaggttg tactatctgt
    10201 atgacctaaa cgatccttca aaacatccca actgcaatac tctgctacta aactagccat
    10261 tgtatgacgt gccaaatggg tatgaaaatc tttgttaatt ccacatcgct ctacacaacg
    10321 cttaacatga tcatttacat attcacgacg gtaaggaact ccacgcttac caggatcaag
    10381 ataaacaaat aaataagttt catctacaac aaaattgcta tttctttttg tcttatttaa
    10441 tacatcaatt aattcttgca atttttccat tactaatggc gtgacgggta ctcttctagc
    10501 agaactaaca gtttttgtag tttcaattcg aaaatcttta ctttttcctt ttactgctgt
    10561 ctgtttataa aacaagattt catttcgttc aaaatctatg tcttgaggct gtaaagcaag
    10621 ggcctcactc acacgacacc cagtataaaa caaaacatga aaaagaacag acatgggtaa
    10681 ttcttcataa ataatcccat aatttaaaaa agttcgtaat tcatctactg ttaaaaactt
    10741 atcttctaaa ctgttaacag actcttttaa atctttaact gttaactgat acttaggcat
    10801 tttaacaaac ttcattggat tctcatttgt caaattcttt ttcatacaat atttaaaaat
    10861 catatttaga acctgaacaa gagattgtaa actattctta gcataaccaa catcaacacc
    10921 attaatcccc ttttctttta aaataaaaag gaatttttgt agttcttctg aagataaact
    10981 acttaatttt tcatcaccaa tccatcgatt aagtatctcc acctgttctt ctcgcttatc
    11041 atacgttgct atcttttgtt cgtttaatga tcgataatat tcaaaccact tttgactaac
    11101 cacactgaat ttatcgttac tagcaattct ttttttctga tttctgtgtt gtctttccat
    11161 ttcaagataa gcaagctgag cttcacgttt agaattaaaa cctcgtctcg tagttcgaaa
    11221 agcctgaaag taccaagtaa tttttcctgt tgctgaaata tgttttttaa aacggctcat
    11281 attttccatt tgttcttacc tccaattacg aaggaaccca acaatcggaa acacttgaaa
    11341 atctttctat ttatgaaata attatacaac atacagataa aaaaataaat tctaggataa
    11401 tcgtaataaa cgaaactgat cacaaaaata ttcttccttt ccttttttta cccattccaa
    11461 gatgtcatct ctaagatagt gtcctctaat accaaaccag cagcatggaa aatcttctag
    11521 ttttataaga cgatttaagg tactatcact tatttgtaat tgttctttta gatctttatt
    11581 cgttaaaact aaaggtaatt gatttattcc cttcatttta tcaatatttt ctggatgaaa
    11641 taaataattt tctgatgtat tacttttatt gttattcttt gacataattg tctcttcctt
    11701 tctattaata atgattaatc tatcagctac ttttgtcaaa agtacatagg aatttcacct
    11761 ctccccaagt ttacggcgag ccttacggaa gtatcattat cccaacttta aatcatcgct
    11821 ttttattgac tataaaaatt attttagaat atttatcgct ccttctttac agcaagaaat
    11881 catggcgcaa ctaaaatatg ctccttaaag tgttaacgta ctgatagaat ctatttaatt
    11941 ttcaatgaac aataggtttt ctacctaaaa gaatctacta attccttaac tattagaaga
    12001 ttcttttaaa cagaaaaagt ggaaagggga cttttttagt tagttaattt taaattttaa
    12061 gatcgcttct attaatttaa tttctagctg acttagcata tattcatcta cataggtaac
    12121 gaattgacct acctcgttaa atccatttgt caaacataac ttagccatat aagaatgata
    12181 atgtttgagt atcatcttga tcgaaattgg atctccttct agagcagata agataatgga
    12241 tagtggaact aataggtact gccgcttttt agatttatct accataggtc ataccccatt
    12301 ttcaattgtt caactgcctt ctttcgttga taccagatac cacttgtgct catattgaga
    12361 attttaccga tttcagcatc attaaaacct gcaaaataat aaagtaggat aatctttctt
    12421 cttatctccg ataactgatc aattgctgct gataactttt gatctgaaat taatatttcc
    12481 attccaaata agaaatagac atcttgttca tcaaaatgag tttgggaata cctgccttca
    12541 tttgaatctg ccaatggttc ctcattatcc tttatgttag cgtttcgttt tcgaatagac
    12601 ttagcttcgt ttcgtaatac ttttttacag taggcatcaa attggtgttg tatagatatg
    12661 tcattgtaat gttgttgcat gataatatgc tcctttttcc ccctttccac taatacaaca
    12721 atcagaaagc cccttttttt cgaaaaaact agaaaaaaaa cataaaaata tttat
//
LOCUS       DAYYEF010000069        12738 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000069 DAYYEF010000000
VERSION     DAYYEF010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12738
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.072"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            97..540
                     /locus_tag="ACHA1B_002396"
     CDS             97..540
                     /locus_tag="ACHA1B_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HFM8703132.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(546..1730)
                     /locus_tag="ACHA1B_002397"
     CDS             complement(546..1730)
                     /locus_tag="ACHA1B_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HFM8703133.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            1998..2696
                     /locus_tag="ACHA1B_002398"
     CDS             1998..2696
                     /locus_tag="ACHA1B_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HFM8703134.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2703..3380
                     /gene="nth"
                     /locus_tag="ACHA1B_002399"
     CDS             2703..3380
                     /gene="nth"
                     /locus_tag="ACHA1B_002399"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140078 - class I DNA-(apurinic or
                     apyrimidinic site) endonuclease activity [Evidence IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HFM8703135.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3506..4039)
                     /locus_tag="ACHA1B_002400"
     CDS             complement(3506..4039)
                     /locus_tag="ACHA1B_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703136.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4336..6717)
                     /locus_tag="ACHA1B_002401"
     CDS             complement(4336..6717)
                     /locus_tag="ACHA1B_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HFM8703137.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6707..7354)
                     /gene="recU"
                     /locus_tag="ACHA1B_002402"
     CDS             complement(6707..7354)
                     /gene="recU"
                     /locus_tag="ACHA1B_002402"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0004518 - nuclease activity [Evidence
                     IEA];
                     GO_process: GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HFM8703138.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7418..7957
                     /locus_tag="ACHA1B_002403"
     CDS             7418..7957
                     /locus_tag="ACHA1B_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HFM8703139.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8047..8466
                     /gene="gpsB"
                     /locus_tag="ACHA1B_002404"
     CDS             8047..8466
                     /gene="gpsB"
                     /locus_tag="ACHA1B_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HFM8703140.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8488..8855
                     /gene="rnpB"
                     /locus_tag="ACHA1B_002405"
     ncRNA           8488..8855
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ACHA1B_002405"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9064..10230
                     /locus_tag="ACHA1B_002406"
     CDS             9064..10230
                     /locus_tag="ACHA1B_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HFM8703141.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10276..11772
                     /locus_tag="ACHA1B_002407"
     CDS             10276..11772
                     /locus_tag="ACHA1B_002407"
                     /EC_number="3.4.17.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HFM8703142.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11853..12536
                     /locus_tag="ACHA1B_002408"
     CDS             11853..12536
                     /locus_tag="ACHA1B_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HFM8703143.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            12545..>12738
                     /locus_tag="ACHA1B_002409"
     CDS             12545..>12738
                     /locus_tag="ACHA1B_002409"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703144.1"
                     /translation="MTEVVSSKIFRIIFRKSYFWNTVYQEVVSLPFSSESQGTISKNS
                     FSCLMNIVTCDSELAGEHRL"
BASE COUNT         4273 a         2230 c         2630 g         3605 t
ORIGIN      
        1 tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa taggaaacaa
       61 aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca actgctaata
      121 gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga aatggaaaaa
      181 gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg gaaaatccct
      241 gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc catcagtaag
      301 ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga agagaataaa
      361 aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag acacgagcaa
      421 ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc aaaagaagaa
      481 tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag tagcaaatga
      541 agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa tccgaatacc
      601 gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc gatgacgcgc
      661 gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt atctgagaca
      721 gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa accataacag
      781 ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt gatgaataga
      841 taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga aaattttttg
      901 agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat caaagagaag
      961 cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg agaaaagata
     1021 gattgaagag agccagctgc caaccaaaca gcaaaacctg ctgtcaataa aggaataacg
     1081 gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga gaaacttaaa
     1141 tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc ataaacggca
     1201 tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa ctcagctaat
     1261 agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc catccatcca
     1321 aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata taaggtggag
     1381 atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca tatcgaattt
     1441 cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat aaggatcgga
     1501 tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa ggcagctaga
     1561 gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga gtgagaataa
     1621 ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc agtgaataag
     1681 acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat gtaaaaactc
     1741 ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt gtttccttgt
     1801 caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag tgaagatacg
     1861 catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg accgatcagt
     1921 gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt atactgtgat
     1981 tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga caaacagtca
     2041 tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa gaatttttat
     2101 ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat ttgcagatga
     2161 ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat cgtctcgtaa
     2221 caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca gatcgatata
     2281 atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa aaaaaatacg
     2341 aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa caagaatttg
     2401 gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa gaagaccatt
     2461 atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag gcttatagtt
     2521 ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt acaaaacaac
     2581 aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa gtagaacagt
     2641 cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag gagtagcgga
     2701 atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga atgtttcccg
     2761 aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca gtgatcttaa
     2821 gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt gcctcttttc
     2881 cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa ataaaaacga
     2941 ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag ctgattgaac
     3001 gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct ggtgtaggca
     3061 gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc gcagtagata
     3121 cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct acggtcatgg
     3181 aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag acacatcata
     3241 cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc gaggtatgtc
     3301 ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa aaggcgctaa
     3361 aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta tgaattatct
     3421 tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt aaatgtacat
     3481 actcagtagc taggatggta acttattaca atttattgcg ataaaaataa aagttgttat
     3541 ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct ataaaataag
     3601 tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt gtaataaaaa
     3661 tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg gatttgggcg
     3721 gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa aaagtgagaa
     3781 tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt aaaagtacag
     3841 aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat aataaacaaa
     3901 atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa aaaagatggt
     3961 gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag ccttctttca
     4021 aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg ggattattaa
     4081 gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata aacaagtaaa
     4141 tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta agctaaatgt
     4201 tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac agcttggtac
     4261 atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac gcttgtagac
     4321 gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg gtgtatggtc
     4381 atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag gagcagatga
     4441 agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag acgctggctc
     4501 gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc tttgactagt
     4561 agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct ggacatagct
     4621 ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat attgatcttt
     4681 gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt ctgtatttgt
     4741 cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta cgtgtgacga
     4801 ttctgaagtg acaggcgtca tttttttatt gtaacctgtc cacacggaaa tcgaataatt
     4861 tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac caagttttgc
     4921 atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata acccagcgat
     4981 ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg tgatcatata
     5041 agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt ctgttccgtc
     5101 ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat tggcgaaagc
     5161 cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat cttgttcttc
     5221 cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc caagattttt
     5281 taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg ctggaacatt
     5341 acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat tatcccagtt
     5401 tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag tttttccagt
     5461 agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca tcgtagaacc
     5521 aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt ctgcgatgtg
     5581 acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg tggaggcaac
     5641 ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat catatagttt
     5701 cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt agacattctt
     5761 atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga cgatcttagt
     5821 attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat taacagcttg
     5881 atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa cagtatctcg
     5941 tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg cttgaggcat
     6001 cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac caaagtacat
     6061 ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat ttacgtagta
     6121 ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc acgcttcttg
     6181 ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa gtttgatcaa
     6241 ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag agagggcaga
     6301 accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat cttctaccga
     6361 cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt cacgcttttc
     6421 tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag atacggtagc
     6481 gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga aaagtcctac
     6541 acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct tgataaataa
     6601 tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct tcttcacact
     6661 ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat ttgccattct
     6721 tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc aaataaggaa
     6781 tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa gataaaggta
     6841 gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga acactattca
     6901 aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc ccattttgtt
     6961 cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag ggaaaagatg
     7021 ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag acgccattat
     7081 agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca cttctcttag
     7141 gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc gccaacccgc
     7201 gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc ccccgattgc
     7261 cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag gcattcttat
     7321 aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct aggccacatt
     7381 atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa aagtaatcta
     7441 tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc ctaaaatcca
     7501 agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag ggctggaatg
     7561 ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag tagcggaatt
     7621 gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg attttggtaa
     7681 taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag cagattatgt
     7741 cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc acactcgttt
     7801 tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc ctggaaaaac
     7861 gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg aaattcggct
     7921 gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt tgatttatca
     7981 acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa aactagaggt
     8041 gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga attcaaaaca
     8101 aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat catcaaagat
     8161 tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg attgagtgca
     8221 aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca acaaacagag
     8281 gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc aaatcttgaa
     8341 cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc agcacaacct
     8401 aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa aacacgtcaa
     8461 ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga cttgatcagg
     8521 ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc ttagcgaaac
     8581 cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct tcggctatgc
     8641 ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat ccggtggaac
     8701 gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt gtctggaaga
     8761 agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg ttttttctcc
     8821 ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag ggaattaggt
     8881 cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta tttttcaata
     8941 cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta ttcggaattt
     9001 gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat aaggagattg
     9061 tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg gctagaagca
     9121 ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa cggacgtgca
     9181 cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg tacagcagat
     9241 cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt gtttgaaaac
     9301 gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc tgtagctgga
     9361 aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac aaaaaaagca
     9421 atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact gacggaaact
     9481 ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt aactctggat
     9541 acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg agcaccattg
     9601 aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga ccgtccattt
     9661 tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat aggccataat
     9721 atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt cagtcaagaa
     9781 atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat tgaattagat
     9841 attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa tgcagaagaa
     9901 atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt caaaacggat
     9961 aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg agaagaagaa
    10021 actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa aacatggagt
    10081 aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa agcaaccaaa
    10141 aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg gggaactcgt
    10201 ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc aattggatgt
    10261 ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga aatcaatctt
    10321 ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc tgaaaaagct
    10381 agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc aaaaaaaatc
    10441 ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga attgtcggaa
    10501 gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca tcgcgtaccg
    10561 gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca atggcaaaaa
    10621 gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa tattgaatta
    10681 acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga tgttttgctg
    10741 aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga tcagcttaaa
    10801 gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc tgaaacagac
    10861 tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa agtaatcgaa
    10921 caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc atttatgact
    10981 ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga tttcaaaatg
    11041 gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga catcgatgat
    11101 aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga atcacaatcg
    11161 ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca atatcctttc
    11221 tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt ttatcgttca
    11281 ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac ttaccctctc
    11341 catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt agatgttgct
    11401 gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg accaacaaat
    11461 gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg ttattttccc
    11521 tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca gcaagaaata
    11581 gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg gatgtcagag
    11641 catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga tgcaacacat
    11701 gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt taatgtatat
    11761 caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct atagatgttt
    11821 tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg atcgctgatt
    11881 atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat accaaaagag
    11941 ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc tttgtgacgc
    12001 ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat gagaacgagg
    12061 caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa cagatctcga
    12121 tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa gcggccgaac
    12181 tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta ggagcaatcg
    12241 gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt gatcctgaac
    12301 tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca gtgatcaatc
    12361 atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac ggatatgaag
    12421 aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt ctggaatggt
    12481 ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa aaatgatgga
    12541 ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta aaagttactt
    12601 ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt cacaaggaac
    12661 aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt cggaattggc
    12721 aggagaacac cgtttatt
//
LOCUS       DAYYEF010000070        12734 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000070 DAYYEF010000000
VERSION     DAYYEF010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.073"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACHA1B_002410"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="ACHA1B_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0015934 - large ribosomal subunit
                     [Evidence IEA];
                     GO_function: GO:0003735 - structural constituent of
                     ribosome [Evidence IEA];
                     GO_process: GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HFM8703145.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="ACHA1B_002411"
     CDS             complement(323..892)
                     /locus_tag="ACHA1B_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HFM8703146.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="ACHA1B_002412"
     CDS             1078..1980
                     /locus_tag="ACHA1B_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /protein_id="HFM8703147.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACHA1B_002413"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="ACHA1B_002413"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000287 - magnesium ion binding [Evidence
                     IEA];
                     GO_function: GO:0004743 - pyruvate kinase activity
                     [Evidence IEA];
                     GO_function: GO:0030955 - potassium ion binding [Evidence
                     IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HFM8703148.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACHA1B_002414"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="ACHA1B_002414"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006002 - fructose 6-phosphate metabolic
                     process [Evidence IEA];
                     GO_process: GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HFM8703149.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="ACHA1B_002415"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="ACHA1B_002415"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003676 - nucleic acid binding [Evidence
                     IEA];
                     GO_function: GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HFM8703150.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="ACHA1B_002416"
     CDS             8548..8733
                     /locus_tag="ACHA1B_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HFM8703151.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="ACHA1B_002417"
     CDS             complement(8795..9991)
                     /locus_tag="ACHA1B_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HFM8703152.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="ACHA1B_002418"
     CDS             complement(10161..11597)
                     /locus_tag="ACHA1B_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HFM8703153.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="ACHA1B_002419"
     CDS             11890..12699
                     /locus_tag="ACHA1B_002419"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM8703154.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3801 a         2673 c         2250 g         4010 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgac
//
LOCUS       DAYYEF010000071        12032 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000071 DAYYEF010000000
VERSION     DAYYEF010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.074"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            560..1531
                     /locus_tag="ACHA1B_002420"
     CDS             560..1531
                     /locus_tag="ACHA1B_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HFM8703155.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            complement(1508..1597)
                     /locus_tag="ACHA1B_002421"
                     /pseudo
     CDS             complement(1508..1597)
                     /locus_tag="ACHA1B_002421"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
     gene            complement(1609..1845)
                     /locus_tag="ACHA1B_002422"
     CDS             complement(1609..1845)
                     /locus_tag="ACHA1B_002422"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFM8703156.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(1814..1945)
                     /locus_tag="ACHA1B_002423"
     CDS             complement(1814..1945)
                     /locus_tag="ACHA1B_002423"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: protein motif:HMM:NF012387.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA];
                     GO_process: GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HFM8703157.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            complement(2021..2404)
                     /locus_tag="ACHA1B_002424"
     CDS             complement(2021..2404)
                     /locus_tag="ACHA1B_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HFM8703158.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            complement(2437..3222)
                     /locus_tag="ACHA1B_002425"
     CDS             complement(2437..3222)
                     /locus_tag="ACHA1B_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFM8703159.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            3400..4500
                     /locus_tag="ACHA1B_002426"
     CDS             3400..4500
                     /locus_tag="ACHA1B_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HFM8703160.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            4490..5314
                     /locus_tag="ACHA1B_002427"
     CDS             4490..5314
                     /locus_tag="ACHA1B_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HFM8703161.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            5311..6126
                     /locus_tag="ACHA1B_002428"
     CDS             5311..6126
                     /locus_tag="ACHA1B_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8703162.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            6123..6953
                     /locus_tag="ACHA1B_002429"
     CDS             6123..6953
                     /locus_tag="ACHA1B_002429"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8703163.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            6960..7991
                     /locus_tag="ACHA1B_002430"
     CDS             6960..7991
                     /locus_tag="ACHA1B_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8703164.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(8098..9371)
                     /locus_tag="ACHA1B_002431"
                     /pseudo
     CDS             complement(8098..9371)
                     /locus_tag="ACHA1B_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9598..9783
                     /locus_tag="ACHA1B_002432"
     CDS             9598..9783
                     /locus_tag="ACHA1B_002432"
                     /inference="COORDINATES: protein motif:HMM:NF024811.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HFM8703165.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            9808..10527
                     /locus_tag="ACHA1B_002433"
                     /pseudo
     CDS             9808..10527
                     /locus_tag="ACHA1B_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010745868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
     gene            complement(10525..11045)
                     /locus_tag="ACHA1B_002434"
                     /pseudo
     CDS             complement(10525..11045)
                     /locus_tag="ACHA1B_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            11333..11986
                     /locus_tag="ACHA1B_002435"
     CDS             11333..11986
                     /locus_tag="ACHA1B_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM8703166.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT         3483 a         2208 c         2735 g         3606 t
ORIGIN      
        1 ataacgtgat tttttgctgt aatgacaagg ttttagctgt ttcagatacc atgtatccaa
       61 aaatagttta ttgagaaaat aggagagtat ttgatactaa ctagtaggaa aaaatgagat
      121 aaaaagtaaa tggaatcatt taaggtaatc tgaaataaaa aatatacagc cctgtggtac
      181 tttacctaca aggctgtata tattttttac tctcagcgtt tttgactccg tgtctgactc
      241 cgttttattg attttgaatg ttattcaatg accatttaac aggtcaaatt tgatgttttt
      301 gattccgtat gacgccgttt gatatctagt gatatagtga tttgagtcta catcgaataa
      361 gggaataaac caataaaaaa tgatttagaa tattaaaata acaaaaaaga ggactacctg
      421 tattagtcct cttttttgac cagattttga ccagtctatt ttacatccta gtatatttat
      481 atgagctaat tttatgatta aatggtaagt ttttccttgt gtgttttagt ttaaactagt
      541 gtgtaattca aaaatctata tggaaggaac agtattaaga atagaacagg gttctctaca
      601 tgatggtgct ggtttacgga ccgttgttta tttaaagggc tgcccattac gctgtgcctg
      661 gtgttcgatt cccgaatcac aaagcaagca gattgaaaaa ggatttggcc agaccatgac
      721 cgctgaagag gtaatggatg agattgagaa ggatgctgtt ttttactttc actcggatgg
      781 cggagtgacc attagcggag gcgaggcact ggttcaggcg gattttgcta aagaaatttt
      841 gcaaaaatcg aaatacattg gaatcaatac cgtactggaa accagctttt gtggtgctta
      901 taatgaaatc caaaaggtag ctccctatgt ggatacattg tttgtggatg taaaaatgtt
      961 taccagcaag ctccacaaac aatggaccgg cttagataac caacaaattt tgaagaatat
     1021 tcgtcgcttt ttaattgagt atcctaactg cgaagtgcga attcgagttc ctgtggttcc
     1081 aggtatcaat atgaacctga ccgagctgct gacgattgct tgttttgtgg cagatcttga
     1141 tcggttcgta ccgttagaat tactaccgta ccactgctat ggtatgcacg gttaccaagc
     1201 attgggactg gagtatccgt tggcagacac gccagcgcct tcacctaaag aaatgtttgc
     1261 attggcagat caactggctc gcacggttcc tcatttgctg gtcacagctt taaccaaaac
     1321 atttatttat ttattgaatc caagctttat cttatggata aatgaaagac actcactagc
     1381 tgcagccagc tcaagaatag agcttttgct gaagtcagtg agtgtctttt tacgatgttt
     1441 tttcgaagtt aatttgtcga atgaacactg gctcaatcgg tacatcttca ctgtttgtcg
     1501 gctgagctgc gatcgctgct acgatttcta acccttggta tacctgtcca aaaacagtat
     1561 aacgaccatc cagctccggt agtcctccaa gctccaagta tgcttgcttt acattagcag
     1621 gtcagcctgc gcctttgtgt tttgcacaat aaaaaactgg ttgccgttgg tgtgggggcc
     1681 gtggtcccct aaggccaagg cgccattaaa atgataaagt ccgcgatgca cttcatcagc
     1741 gaaaaagccc tcatagctgg aaacagcttc atcaccagaa ccatccaaag cgccaccttg
     1801 aataacaaat tccttaatga cacgagccga aaggtgtgtt gtcataaacg ccttgctcag
     1861 ctagggagcg ccagttggct acagccaggg gagcttggtc aggaaataag cggagacgaa
     1921 tttcaccagc atcggtgacc agcacacaaa cttcttcctg ctgcggtttt tctaattgaa
     1981 agagaggaag gtttgcaact gaaacgcctt gatcctgcca tcaaatatcg aaaatccgcc
     2041 actcgacctt cgcctgatca ccaaggcgag ccattcccaa taaaacggta taggcggttt
     2101 catccgcttg aaaggtcaat tgcagctgtc ctcgtaaatc gttgtagtca tctggggcgg
     2161 ctacttgata aaaaagatga aactgcgcat gcaaatattc caaaggctga tctttaaagg
     2221 ctgcaaaata agcctgaact ttttcccgct gcaagctgtc agccaccaaa aaattttcca
     2281 gttgttgttt tggaacggct gctaacaagg atcggcaaac cgcctcaatt ttcaacgcat
     2341 cccaatgtcg cgcaattaaa taatggatgg gtgcctcttg attgtagtcc cacaggttgc
     2401 tcattttttt caccactttc ttctattata taggaatcac aaaatcggca gcggcgtcag
     2461 gcggcgttct tttccttgaa tgactagcaa cttttctacc tgacagtctg ccaacagctg
     2521 actcattttt ttaaagccca gctgataatc ttcggcaaca tgagcatccg agcctaaggt
     2581 aaagagcttt ccgccgacac tttgatacaa aggaacggca taacggtaaa ggtcttcgtt
     2641 gccgtatttc aagaagctct tggcatttaa ctccatcgcc aattctcgtt caacaacctt
     2701 tttgaaaatc gttagcagct gagcctcaaa atgctccgcg aattcttccg ctgtgaaggt
     2761 gaagcggcgt aatccataat caaagtgagt caaaatatct ccttctggaa aatccgtcaa
     2821 gacctgcaac atctgatcaa aatattcctt ggtagtttga atgggatctt tggttaaaac
     2881 cacatcgtcc atataatcaa agcggccatt ttgatgaata cttaccagct ttaaatcata
     2941 aggatgctga gcgaggtaat ccacgatccg ctcttcttgt cctggaacaa cgccaatctc
     3001 gatacctcgc agaaatttgg tggaataggt ttcttttaaa gagtccagtt tgtttatata
     3061 ggctggataa tccggaatgt catcttttcc ggtagatgga ttgtttaaat caaagtgatc
     3121 cgtagaaacg aaaaactccg gctgataggc taaatagttt tcaaattttt cctctgaatc
     3181 aaaggaaaaa tacgtgtgga gatgctgatc ataatactgc atagggagcc tccttttttc
     3241 tactatcata ccgcaaaagc tttagaaggt taacgggaat tcgtcgaaat ttacaaacca
     3301 tatacaacct ttacattgtt catgaaacct tttcaagaaa ctgattctct cattacaaag
     3361 ctttgttaga atggaattat cgaaagggga gaagaatgaa tgaaaatgaa tgaaaaaatt
     3421 cgtaacatga ctatcggttt attttgtgca gcaacagtaa gtatcctgct gacaggctgc
     3481 ggctcaggtg aagcaacgaa gcaatcggct gcggcagacg actctttaga tacgattata
     3541 gaaaaagcca aggaagaagg agagattgcc agcttgggaa tgccggatac ttgggcaaat
     3601 tgggtaggca cttggaacga ccttgaaaaa gaatacggct taagtcacgt ggatacggat
     3661 atgtccagtg cagaagaatt ggctaagttt gaatcagaag gaaaaaatgg aaccgccgat
     3721 attggtgatg tcggtatcag cttcggtccg ttggctgaaa gcaaagagtt aaccttacct
     3781 tataagacca actattggga ggaaattccg gattgggcaa aggatgatga tggggattgg
     3841 ttgttaagct atacgggaac catttccttt atcaccgata aagagaatgt gaagcaagca
     3901 ccgactagct ggaaggagct gcaagagggt gactatcaag ttagcgtggg ggatgtgacg
     3961 attgccaacc aagcacaatt tgctgtattg gctgcggcga ttgccaacgg aggtgacgaa
     4021 aaggatattc agccaggtct gaattactac aaaaaaatgg cagaaaaagg ccgtttgtcc
     4081 accgttgatg ccagcgtagc aaatcttgaa aaaggtgaaa tcgatgtggc agttgtttgg
     4141 gacttcaatg gactaaatta tcgtgaccaa attgactccg agcgttttga ggtaactgtg
     4201 ccaacagacg gctccatcat tagcgggtat acaaccttaa tcaataaaaa tgcccctcat
     4261 cccaatgcgg caaagctagc acgggaatat attttatctg atgaagggca aatcaatttg
     4321 gcaaagggct atgcgcgacc tattcgcaag gtagagctgc ctaaagaagt agctgaaaaa
     4381 ttactgccgg aggatgctta tgaagcggcg gtgccagttg aagacaatga agcttggaac
     4441 aagacctctg tagagcttcc agagctttgg caggcggagg tactgaccta tgcaaagtag
     4501 acttgacaaa ctgattgtag ttatactaga cggctgtcgc tacgacacag ccgtcgccca
     4561 gcttgggttc atgaatcatt tagttgagca ccagcaagca agcttattga aggtaaaaag
     4621 tgagctgccc agcaattcac gtccgttata cgaagtactg atgaccggcg ttccagccta
     4681 tgaaaatggc atctatagta attaccatgc tcagcgatcc aaagagtggt cgctgtttga
     4741 attagttaag gaagctggcg gaaaaacagg agccgccgct taccactggt acagcgagtt
     4801 gtacaatcaa gccccctata atcgtttggt tgatcgcatc cagcatcagg aggagcgact
     4861 gattcagcat ggcatctttt atagtgagga cacttaccct gattcgcatt tatttgcgga
     4921 tgcccattat ttagtgaatc agtatcagcc agactttttg gtcgtacatt cgatgaatat
     4981 tgatgatgtc ggtcacaaat ttaccgccga ttctcatgaa tatgcagcag cggttaatca
     5041 ggcggacaga ttattggcta tttaccttcc tgaatggctg caaaaaggtt atcaagtcgt
     5101 ggtgactgcg gatcacggga tggatgcgca cggactgcat ggcggcagct tggctgcaca
     5161 tcgtgaagtt cctttttatt tgatttcaaa taaacgccaa aagctgaagg aacaaactgt
     5221 accacagctg ctggcggctc cattgttttg ctggttatta ggaattgcac cgtcagagaa
     5281 aatgcaggac attcaagaat tgatgagggg atgaaagaga tgaaaaaacg cttggttctg
     5341 gttcctgcct cctttatctt ctgtgcattt ttactgctgc cgctgctttt tatggttctg
     5401 tgcagcttgc acagtgattt aactaaccag tggacattgg ccaattacag tgatattttc
     5461 agcaacaaat attacacaca ggcctttgtt aacagcgtac tgattgctgt cagctccagt
     5521 gtgattgggt taatcgggac gtttatttta tgtttatgct taatgaatct atcgactaaa
     5581 ttgcaggaga aaatcacctt tgtttccaat ttggcagcta attttgctgg gattccgctg
     5641 gcattctctt ttattatttt gttggggaat gtaggtgtgc tgaaaatgat tttgccattt
     5701 ctagcggact tcaatttgta ttcttggtgg ggattgacca tcacgtatac ctatttccaa
     5761 attccgttag gggtcttgtt tttgtatccc agcatgaagg aagtgaaaaa ggaatggctg
     5821 gagtccgcac aattgctggg cgcttcatca gcgtatgctt ggttcaaggt ggctttgcct
     5881 tttttgcgac catcgattgc cagcaccttt gtcatcttat ttgctaatgg catggggacc
     5941 tatgaaacag cgtatgccct gaccagcagt aatgtaaatc ttttaacgat tcgaattgcg
     6001 gctttagtgt cgggagatgt gttcgccaag cctaatttag gcagtgcgtt ggcagtcgct
     6061 ttaggtgtcc tgctggtaac ggcaatgttg attattcaaa agaaaggcaa ggtggtgcag
     6121 acgtgaaaaa gttaataaaa ccgattttgt tctgctttgt cctgtattac ttgctgccga
     6181 ttattggaac gattttgtat gccagctcca ctaaatggtc aaaatcgctt ttacctagtg
     6241 attttacctt gcaatggttc caacagctgc tgacggacag ggaatttatt gctgcggtgg
     6301 gtcgctcact tttattagca ggtgtggtct tggtgacgat tctgttgttg atgattccca
     6361 ccattatttg gattcatttg tatttccctc gtttgaatcg ttggctggaa aagctgctcc
     6421 tgctgccgta tgctttacca ggagtgattt tggtaacggc tttgcttcga acgtatgctg
     6481 aaactggtat cccaatgttt gtagtgttgg taggtgcatt gtttattacg gcgttgccga
     6541 ttgtctatct tagtcttaac aaccagatgc gcttaattaa tctgaaggaa ttagtggatg
     6601 cagcagaaac cttgggcgcc ccgatgtcta cgattattat ccaggtgctg tttccaaaca
     6661 tccgtatcgg tgtgacccta gtttctctga tgattttttc ttcggttttt ggggagtaca
     6721 tgctgacgaa cctgttgatt ggcggtcgat ttcagacggt acgcatctat atgctgcggc
     6781 ggatgaacga aaacggccat ttggctagcg ctgtgatggt tttgtatttg ctgtttatgg
     6841 tgggaattgc tttaactacc tttatgctga cttatcgaca aaagcaacag ctgtccctta
     6901 agcagacgag ggaagagaag cagtcgaaaa agaagccctt aaaggagttg tgacggaaaa
     6961 tgtttttaga aatacatgat ctcaatctgt tttttgatga aaaacagatt ttagctattg
     7021 atgaaattca gattgaaaag ggtgagctgg ttactttact aggtcccagc gggtgcggaa
     7081 agtctacgtt gctgcgctgt atcacgggat tggaacaacc aaagagcggt gagattgtgc
     7141 tggacaatga gaatattgcc gataagccta cgaaggatcg caatatcggc tttgtttttc
     7201 aacagtatgc attgtttcca actatgactg tttttgaaaa tgtagccttt ggtttgaagg
     7261 taaagaagct gagtcctgag gtgattcagg aaaaggtttt tgagatgcta tcattggtgg
     7321 atatgacgga gcaggcagat aaaaatgtcc agtttctttc tggcggtcaa cgacaacggg
     7381 tggcactggc tcgctcattg gtcactgaac cgaaagtcct gctgctggat gagccattaa
     7441 gtgctttgga tgcccgaatt agaaaacagc tgcagcggga tttgcgcgct atccagcaat
     7501 cgctagggat gacgatgatt tttgtgactc atgaccaaga agaggcgatg cgaatcagtg
     7561 atcggatttt tgtgatggaa gctgggcggg tggctcaggt ttccacctcg aaggaattgt
     7621 atcagaatcc tcagagccga tttgttgcgg aatttatcgg caactataat cgtttcgaat
     7681 ggtatgagct gaatcagtat acccacgagt tttccgctaa gggcaatcgc tgcatttatt
     7741 atttaagacc ggagctgatt caatttgaac cggttcctca gggggttaag attccggttc
     7801 tatggaagga atcatttatt ttaggcaaca ttcaacggta tgtttttcaa acgctggagg
     7861 gcaaagaaat tttagtggat cggttgaacg atcgggaaga gaaaattagc gatgccttat
     7921 acattcagct gaaagatatt ctagcaatcc ctgtggaaat tgatactcag cattttgcac
     7981 aacaaagcta gtgtatagtc ggcaaacatt tctggctctt tgtcaaatag gactgataga
     8041 gtgatataag aacatctaag gtagaattga ttttctgctt tagatgtttt tttatgttta
     8101 ataagtgatc agatgattga ttaagaaaat tctggttctc atcctaaccc gtaagctatt
     8161 cgtttcaatg ctttgatgtg ggtatgcaga ttttctattt tgccatttga gtaaggcaac
     8221 tctaaggcta aacgaatgcc ggattcatag tttataaacg ctttttttat atgatgcagt
     8281 tctcttggaa ccgacttggg cattgttttt acaagctgaa agaagatgtc cgcttctttg
     8341 tcataaaaag cttgaagaat ttcttgatag taagcataag ctattcgtag ttcatcagaa
     8401 gtagaaagta gacgttctac gacttcactt tcggttaaat aggcccaacc aaaattacgc
     8461 cattttgtcc atttatcata aacaagcgtg tcctgtcgtt tgatcagaag tcgagataaa
     8521 gccttcactt gtcgatagtg tttggcttgt attggatcgt ttcggtcgaa gcttttcatg
     8581 actcatagtc aaatatcctt aaaactgcga atgaggtgct tgacgatgtg aaagcgatcc
     8641 acaacgagtt tggcatgagg aaagcactct tttatcagca aagcataaga ggcgttcata
     8701 tctgttacga gtatttttac gtttaaacgt gcacgtcgtt caaattgcat aaaataagaa
     8761 atgagatctt tcttcttacg tgaaggaaga atatccagta atttcccagt atcgccatcc
     8821 atacaagaaa aagaataggg accgacttga tttttcaatg aacgaaattc atctaccaat
     8881 gaacagcgag gcaaccaatt tattttcacg tttgtcatgg ggagcagaga agcgagtgtt
     8941 cgcgaaacgg ttgaccaaga aacgccgcaa tgtttagaaa tcgtcgtcat tgcttgtttt
     9001 tcagtcaatt cctccaatat tttataatgt acttgtttgg cgataaaaca gtttttttca
     9061 acaatgtagg tattcgccgt aaaataggtg tgacagccac gacagaggta ccgttgcttt
     9121 gccaaagcaa gataagtccg ttgattcgca cacttattga gaaggaccag cgattttttc
     9181 tttccgttct taacgatcag cccatgttga ttcacctgtt tacactgagg acagggctga
     9241 atcgttttaa tgagcgtggc agaaacaacg atactgttga ttgaatgtat ttttttcttc
     9301 tcgacatgag tgatttgaat gtttccatct ttgattccta gtaatagttt gataagatga
     9361 agatcaggca tacagaacgc tcctttgatt gtgttgtggt gattcaattc taacggagct
     9421 tctgtatgtt ttgttttttt atgctcaaaa ggactgatag aatgatttac tatcagtcct
     9481 agaaattata gcgccacatt tctttcacct ttgacttttc agacggcagt ttttatgctg
     9541 atactgtaga gagagcagga cacagctttt gcttgttttg ggtaaggggg aaagaagatg
     9601 accaaagcac ttatttttga ttttgatggg acgatgattg acagtgaatg gatgttttac
     9661 gagagtattc atcactattt actgaagcct atttactgga gcagttcggc tataaaattc
     9721 cttttgcaga ctatcaacaa ggtgttggga cggcagcaga actgtccttt tatgaaggga
     9781 taagtcaagc ggttgggaga ccagtggatg ctgaacattt tgagcagcgg atcagcagca
     9841 ctggaaaatc ggagtagtct caattctgaa ctgcgggagc tagactattt ttttgaagca
     9901 catccgatga ttaaggaaaa aattgattcc tttgtgacga tcgatgatct tcaggtcggc
     9961 aaaccagatc cagaaggtta tttgttgtgc ttgaaacggc tgagggttga acaggctgtt
    10021 gtagttgagg atagtccagt cggtgcccaa gcagcaccgc atatgacagt tgatgtacaa
    10081 gcgttggatg cagatttttt cgcctttagc gggcataaaa tgtgcgggcc gacaggaatc
    10141 ggtgtattat atggcaaacg tcaattgtta gaacaaatgg agccagtcga attcggcggt
    10201 gaaatgatag attttgtcaa tctttacgat agttcatgga aagagctgcc atggaaattt
    10261 gaagctggta ctccgaacat tgcaggagca atcgattact tgaatgagat tggtatggag
    10321 aatattcatc gttatgagca agaactggtt gcctacgttt tacctaaatt acaagcgatc
    10381 ggcggtatca ccatttacgg accgcaagat cctgaacatc atactggcgt ggttgctttt
    10441 aatttggatg gcatccatcc ccgtgatgtg gcgactgctc tggatatgga aggtgtcgct
    10501 gtacgttcag gacaccattg tgcacaacgg ttcatcgacg atttctgttt gactaattgg
    10561 tcgtttaaac agtcgatgat aatgccgttt gagcggctcc aatgtcgtgg aatctttgag
    10621 taagagtttc caatatcgct tgagccgacg gtacttcttc tgattttcag attacgtgat
    10681 tgattttcgt acagttctat gagaatcgcc tgtttcagtt cctttgttag ttgatgatgt
    10741 tcatcaacta agtccgtttt cgcagaaaag gtctgcccac aatcatagca tagaaaacgg
    10801 gtacgtttta attctaaaat agtcaacttt tctttgactt tcaacatctg agtacgtgtc
    10861 gtataggaac cgttgcggat aatacgaatc gatccacagt gttcacaatg ggaaggtgag
    10921 tcatccaatc tccctttaat aaactgcgct tgaacgcctt tatattcttt ttcaatcagc
    10981 cattcttcat caaaaaataa atgtttatct gttaatccga gtaattttct agtatgatta
    11041 tccatagagc gactcctttg gtagggtgat gttttggtcg actaaatttt accaaaagtg
    11101 agtctctttt tgagttgaaa cgaagaaaaa gtgttagtag aaaatcgcct tcgattttcc
    11161 aacaacacaa aatattatag aagccttttt tctaaaggat ttcaaggtgt ctgtttgcat
    11221 ttattaaaaa aaagaaaaag tattggcaac agaaggcgtc accaacacta gatattatag
    11281 agccataata tgctgtataa tatctagtgt ataggcttaa gtggaggtat atatgaaaat
    11341 attaactgtt gaagatgata atatgataag agagggaata agtgaatatc tttcagaatt
    11401 tggatatact gttattcaag ctaaagatgg aagagaagcc ttgtcaaaat ttaatagcga
    11461 tataaatttg gttatcttag acattcagat accttttata aatggtttag aagtgttgaa
    11521 agaaattaga aagaaaagca atttaccaat tctaatcttg actgcattta gtgatgaaga
    11581 atataaaatt gatgcattta ctaatttagt agacggatat gtagaaaagc cattttcatt
    11641 gccggtctta aaagctagaa tagattcttt aattaagaag aattatggac atttagagaa
    11701 gtttgaatat aaggatctat cggttaattt taatagctat acagctaaaa taaatggtga
    11761 agaaatagat gtaaatgcaa aagaactaga agtattaaaa tgtttattgg ataataatgg
    11821 acaagtgtta acaagaatgc aaattattga ttatgtatgg aaagatagcg aagaaactcc
    11881 ttatgatcga gtaatagatg tatatataaa agaacttaga aaaaaattac aattagactg
    11941 tataactact ataagaaatg taggatataa attggagaga aaatgaaaaa attaaagata
    12001 tttccaaaaa tgttcataca aatattttct gt
//
LOCUS       DAYYEF010000072        12031 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000072 DAYYEF010000000
VERSION     DAYYEF010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.075"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..453
                     /locus_tag="ACHA1B_002436"
     CDS             <1..453
                     /locus_tag="ACHA1B_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016181348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8703167.1"
                     /translation="LKHLGEYEVLDTAMLTKGIGQILSTITYFITAVAGISLFIAGVG
                     VMNMMYISVSERTKEIGIRRALGATRKSIMLQFLLEGLILTLSGGLIGYLLGMALAYS
                     VGSLIKVNVSLDLFTILLAVGVSSVIGLVFSVMPASEAAKKDLIDILR"
     gene            854..1459
                     /gene="fic"
                     /locus_tag="ACHA1B_002437"
     CDS             854..1459
                     /gene="fic"
                     /locus_tag="ACHA1B_002437"
                     /EC_number="2.7.7.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_function: GO:0070733 - AMPylase activity [Evidence
                     IEA];
                     GO_process: GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein adenylyltransferase Fic"
                     /protein_id="HFM8703168.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1475..2047
                     /locus_tag="ACHA1B_002438"
     CDS             1475..2047
                     /locus_tag="ACHA1B_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703169.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2299..2556)
                     /locus_tag="ACHA1B_002439"
     CDS             complement(2299..2556)
                     /locus_tag="ACHA1B_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703170.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(2682..3497)
                     /locus_tag="ACHA1B_002440"
     CDS             complement(2682..3497)
                     /locus_tag="ACHA1B_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703171.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4014..5339
                     /locus_tag="ACHA1B_002441"
     CDS             4014..5339
                     /locus_tag="ACHA1B_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFM8703172.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5332..5682
                     /locus_tag="ACHA1B_002442"
     CDS             5332..5682
                     /locus_tag="ACHA1B_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703173.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            5679..5849
                     /locus_tag="ACHA1B_002443"
     CDS             5679..5849
                     /locus_tag="ACHA1B_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703174.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHKYEYYIGY"
     gene            complement(6753..7028)
                     /gene="prgO"
                     /locus_tag="ACHA1B_002444"
     CDS             complement(6753..7028)
                     /gene="prgO"
                     /locus_tag="ACHA1B_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA segregation protein PrgO"
                     /protein_id="HFM8703175.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7000..7953)
                     /locus_tag="ACHA1B_002445"
     CDS             complement(7000..7953)
                     /locus_tag="ACHA1B_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM8703176.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            8565..10058
                     /locus_tag="ACHA1B_002446"
     CDS             8565..10058
                     /locus_tag="ACHA1B_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HFM8703177.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10193..10489
                     /locus_tag="ACHA1B_002447"
     CDS             10193..10489
                     /locus_tag="ACHA1B_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFM8703178.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            10590..11441
                     /locus_tag="ACHA1B_002448"
     CDS             10590..11441
                     /locus_tag="ACHA1B_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703179.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11462..11674
                     /locus_tag="ACHA1B_002449"
     CDS             11462..11674
                     /locus_tag="ACHA1B_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703180.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         4127 a         1849 c         2244 g         3811 t
ORIGIN      
        1 ttgaaacatt tgggggaata tgaagtgtta gatacggcta tgttaacgaa aggaattggt
       61 caaatcctca gtacgatcac ttattttata acagctgtag caggtatatc tttatttatc
      121 gcaggggtag gtgtaatgaa catgatgtat atatctgtat ctgaacgaac aaaagagatc
      181 ggtataagaa gagccctagg agctactcga aaatcgatta tgctgcagtt ccttttagaa
      241 ggtttgattt taactctttc aggagggtta attggctatt tattaggaat ggctcttgct
      301 tatagtgttg gttctttgat aaaggtaaac gtgtcacttg atctatttac tattttacta
      361 gcggttgggg tatcttcggt tattggactg gtcttttctg taatgcccgc ttcagaggct
      421 gcaaaaaaag atttaattga tattcttaga taaaatcaga atgacaagaa tatttacgtt
      481 ctagattcta aaataaaaca caaagagacc aaccaggcac cctattgttt ctttgtagta
      541 tagagatatt ctttggcttg taagagatca atagagttag gtgaccggag ttcgaaataa
      601 aggaaatttt tgattgtata ggagaattct ttatccctaa tatttagaat tttgagtatg
      661 ccatgttgat gttttagatt ctctataaat atagaggtgt atcaaaggtc aactagactg
      721 tgcaaaatag agacacttga aaaatctatc gggggtcaga aacttaatag tttttgacac
      781 ataaacaaaa tcgcgatata atggggttga gagtgtttca taaacttatg tcataaagtt
      841 aaggagattt cgcatgattt tagagaataa attgggatta accaatcaag ttgagttggc
      901 taaggttgaa gaaaaactca gtaaacaaaa agcgaaagaa ttgtacgatt gtggaaaaat
      961 aaatgaaatc gaagttggta catttaaagg tttatctgaa attcatgaat ttctattttc
     1021 ggatatttac gattttgccg gaaaaatccg atcggtcaat attgcaaaag gaaattttcg
     1081 atttgcacca gttatgtatt tagaacattc gttacagcat attgatcaga tgccacaaac
     1141 ttcttttgaa gagattatca agaaatatgt ggagatgaat atcgctcacc catttcgaga
     1201 aggaaatggc cgaagtacta gaatttggct ggatctcatt ttaaaggaag aattgcaaaa
     1261 agttgtagat tggaacttaa tcgataaagc agactatctt tctgcaatgg agcgaagtcc
     1321 cataaacgat ttggaaatac gctatctaat ttccaatgct ctgactgata aaattgacga
     1381 tcgcgagtta tatatgaaag gaatcgatgt cagctatttc tatgaagggt attctgagta
     1441 tacgatagat gatttgtaaa agtaggtgga ccaaatgacg aaatatggat atgcacgtgt
     1501 ctcaaccgct tctcaaagta caaaagaaca aattcaacag ttgcttgaga acggcgtaga
     1561 gaagaagaat attttttcag aaaaatttac gggtacaaaa cgggatcggc caaaattcaa
     1621 tcagctgttg gctggtctga agcctggaga tgaaatagtt gttacgaagc ttgatcgatt
     1681 tgctcgtaac acgagagaag cattagagat cattgaacct ttactcgatg ataacgtaac
     1741 gatcaaggtt ttgaatctag gaacgattga aaatacgtcc atggggcgaa tggtgacacg
     1801 gacgttgttg agtgtagcag aaatggaacg tgatatgatt gtggaacgta cccaagaagg
     1861 aaaaatgttt gcaagaaaga ataatcctaa tttcagagaa ggacgtccga aagcaacaat
     1921 cacaccgaag aagaggcacg catatgaact gcttacttca ggtaaatcgt ataaggaagt
     1981 tgaagctata accggtttca gtcgcagtac gctttttaga ataaagaaga aaattgaaga
     2041 aagttaaaaa agaagtctca gcgaaccaga caggtaaata cttaatgcgt tctagatatg
     2101 agtctattag catgttgtga aatataatat ttttttattt acttgatttc tgctcaaaaa
     2161 atgtgtatgg taactgtaaa aggtaaagta attaaaggta tgctagccac gcttactata
     2221 ttaggatacc atcatatatt tataatgaac gatttgttcg tctaccaaac aacacatatc
     2281 gttcagcgta agtcacgttt aggaacgtgg cttttttagt gttattatcg ataaataatc
     2341 tattgactct attgatttta tctccatatc cctacggtgt tgattgtctt tagatctttc
     2401 atttaagaac caaataacta tcataaaaat cagcactgct gctaatataa taaacagcat
     2461 tcctattgtg atattaccta ttgattttac cataactacg attaaagtaa taatggcatt
     2521 caagtctcct ttgttctcta tatataaatt agccataaat catcttcctt tcaaattaag
     2581 atacttgttt gataccaata aatagtaagc gtggctagca tacctttttc tgtaatagca
     2641 agtgttctaa tagtccaaac ttaatgatgg accgatgcta gttatagtac agtaatgttt
     2701 tctttcttat ctagattttt agtaagctct atcagcaaat ctaacaaatc tgagtccttt
     2761 tcagaaacta aattaaatct agtgtttaca acaaagtttt catgttctat attgtttaga
     2821 ttatttgcgg aaaggagggc ttctagatct tgacattcaa atctatatgc atcgtcataa
     2881 atcttactag aaggagtgct taattcgaaa ttacttattt tctcatcttg gaccaagata
     2941 aatttataga tagtatcttt ttgtgttttt cttttaaaaa cacaacagag tgtgttataa
     3001 ggaacgttat aattttcatc agcctcattt tttctccatt caaacaaatg ataaactgca
     3061 accaagttgc catcaatttc atggacagtg ctctcggtaa catcctttaa agaactatca
     3121 agggctaatt tatagtaact agagagagga agtaaaattg tcgatttact gagatggtta
     3181 tcgtctatac gtgcaatcat acctaaatca actaaggttt tattccaggt gtttatagtt
     3241 ttagttgtca ctcctagaga ctctgctatg gtattgaccg aatgccagga atccccgcct
     3301 tcattctttg ccttaaaaca gtaatacaga tataaattaa tagctttgtt attcggtaaa
     3361 tatttttcaa gttctgttgg tagaataaag taagaatcct taatgttttt tctgaactgt
     3421 ctccagtctc tgtagttttg tttataaagt tgtgaaacgg tttttccacc tttagaaagt
     3481 cctgctatct taaccaatct tattgctcct ttcttgaatc tgtcatgatc atacagtatt
     3541 ttttacttgt agtccagcac cttaatatat tatcctatgt aattaatttc gtactagata
     3601 gtaattattt tttatttaat tctctagtca cttacaaata agttatataa actacgatta
     3661 ataaattatt acaaaaacta ttaagaaaac ttctacatac aactattaca aaactattaa
     3721 gaaactgaat actcctattt tttgttttta aggaaagttt tttctttttt gaatttctta
     3781 tttttttcta atataactaa gcaaaactgg ataatacgac acttattttc aaattttcac
     3841 aagactaata gtaaatatcc atttaataaa gtgatacaat gtgttgattt tacaaatcaa
     3901 cagaagaagt agggaaataa cttacctatg cttctttttt tgtacattta atcgattctt
     3961 ctttacaaaa acgaacgtat gtttgtataa tgtggaagaa tggagtgtta tttatgatgg
     4021 attattcaaa agagccagta aatgattact ttttgatcga tatgaaaagc ttttacgcaa
     4081 gtgtcgaatg tatagaaagg aatttagatc cattaacgac tgaattagtc gtcatgagtc
     4141 gagcggataa tacaggatca gggttgattt tagcttcttc accagctgca aagaagaagt
     4201 acggtatttc taatgtcagt cgaccacgag atctaccgca accttttcct aaaacgttac
     4261 atgtcgttcc accacgcatg aatctctata ttaagcgaaa tatgcaggta aacaatattt
     4321 tcagaaggta tgtagcagac gaagatttat tgatttactc gatcgatgaa tcgatcttaa
     4381 aagtgaccag atcaatgaat ctttttacga ctgaaggaac aagaagtcaa cggagaaaga
     4441 agctggctca aatgatccag gagaatatta aagaagagct aggattgctt gctacagtag
     4501 gtgtcggaga taatccctta ttagctaaac ttgctttaga caatgaagca aaacataatg
     4561 atggattcct tgctgaatgg acgtatcaaa atgttcctga taaagtatgg aatattcctg
     4621 aaatgacaga cctttggggt attggatctc gaatgaaaaa aagactcaac caaattggta
     4681 tcatgagtat taaagactta gctaattgga atccatacac tattaagagc catttaggtg
     4741 tgattggctt acagctgtat tttcatgcga acgggatcga tcgaacagat atagcgatcc
     4801 caccagaacc gacaaaggaa aaatcatatg gtaattcaca agtgttacca cgagattata
     4861 ccaggagaaa tgaaatcgaa ctggtggtaa aagaaatggc ggaacaagta gctattcgta
     4921 tcaggcaaca taactgtaaa acaggttgtg tccatttata cattggcacg tcgatcttag
     4981 aaacgagacc aggtttttca caccagatga agatccctat aacagataat acaaaggaat
     5041 tgcagaatta ctgtcttttc ttgtttgata agtattatga aggacaagaa gtaaggcacg
     5101 ttggaataac ctatagcaag cttgtgtaca ctgattcgct tcagctggat ttatttagtg
     5161 atccacaaaa gcaaattgac gaagaaaatt tagataaaat tattgacaag attcggcaaa
     5221 aatatggttt tacgtcgatt gtacatgctt cttctatgtt agaaggcgct cgtagtatta
     5281 ctagaagtac attggttggt ggccatgcag gcggcgcagg agggcttaaa aatgattgat
     5341 tataatgatc gtggacgttt aaagtgggca ggtttttatt tatctgatca tactgaaaaa
     5401 attgatgccg acaatgaaca acgagccaat caaaatttgg caaaagaaca aatgacgact
     5461 gaagaggttg cggaagtatt gaacgctgca gtcataaaaa atagatcagt atgtattcaa
     5521 aaagaagaac gaaacgctga aggatactat ccagaagata ttgttagcaa gatcttaggt
     5581 agtgatgagc tggggatcta cgttggaaaa aacaaagttc actacgacga aatacgtcat
     5641 atcgaatttt accaggataa taaatggggt cgattagaat gaacattatc cagcaatatg
     5701 agctaaagta tataaccttt gatcagctat cagaagagat ttggggttat ggccagcgtt
     5761 tgataaatga ggttggtgtt gaacgcttct ctttctatgt agaagctgca gcaggatacc
     5821 ataaatacga atactatatt ggctattaaa gtgcaataaa attatatttc ttttatgttt
     5881 tacattttgt atcaattctg ataaaattac ctataggtaa ttaaaaaata taaaaaaact
     5941 agttacaacc ttaggacgtt gtaactagct tgaagcatac tagagctaac taaaatagca
     6001 ctagaaagca atgttaaacc cgtccaacaa acttgattta acattgagac cagcttattc
     6061 agctaaatat agttgaataa gcttcttttg ttttaaaaaa acaaaaggtg tactacgaat
     6121 aacgcaagta aaagaaatac tattacaacc agtaggctac aagtaagtat tactaaacat
     6181 tgcgtagtta gaacctttgc tctattgtct aaagccacaa aattagagat cagctttatg
     6241 atgctaagag cgagctgcat ccatgcggac ataggttctt ttgacactat taattctcct
     6301 ttttaggata agggaaattg ctagtagttt tttcattagc accatccccc ttcatttgat
     6361 tgagtctagt gctgctgtga tagtttgctg tttaatatgc ttacattctt attataacat
     6421 aaatgaaaca aacacatggt tagaggtcgt atcaatcaaa atagtgtctc acaaacgatt
     6481 tattacttac tcctgctgac taacggactg ttcttcagta actgtaacta tatgtttgtt
     6541 aaaaccacca ttacctgtag ataaaaacca atatatttac tatactcact atattaaata
     6601 tatttagtat agtaaaaact agaaacaata aaatttgtga atgttgtata cccccaaaca
     6661 atacacatat tttgaaggat taggattaat aaagctaaaa atatagtaag tatactaaat
     6721 atatttacta tatctagtat acttactata ttttaatctt ttgatcgtct attatatata
     6781 atccgttcct cgtcgtttaa agtatcaaca taggcgtcca ttgcaagttt gactatttca
     6841 tacataggaa tatcttttgc ataactaaga tcccgaatgg tttttagtac gggaggatct
     6901 acttgaactg gttttctttc tttcgcagtg tactttcgtt cccctaactc gacattaata
     6961 tcatctttaa ttgaaatatc ttcagcacca attttcttct tatctttgtt cgttggtaat
     7021 aatgccattt agtttaatct cctttccaag aggtaggata tgattggcca ttgagtcagc
     7081 atatttaggt gtataatcaa atccttcaat atcaccatgt tgttcatagt attcaattct
     7141 ttcttctaat tctgtaaaga tgtctgcaaa aatagcccac catcttcgat ctacataatc
     7201 atttaattgg ataccattct caccatacat ttctaaccga tccgagcctt taacaatgct
     7261 tttaaaaatg tttgattcac catacttatc aattgttttt tgatagtttg cgtgttgaga
     7321 ggaacgtcgc actgagaaaa gaacaggcaa aattccaatg atttgaagat gagactcttc
     7381 aaaattcgtg acaatcggaa ctaaaacttt attaataaaa tcttctgttc cttccattgc
     7441 gtaccgtttt aattcttgca ttgcaataat ataatctgca gcagttaaga atgcacgaac
     7501 cacattatct gttgatggtg ggcagtcgat aaagatataa tcgaaatttt ttctcaattc
     7561 ttctaaaggt ttaatgaagg ccaatgatct cttacgacga tcaggatatt tttcggacaa
     7621 gtattcatta agttcttcag atccaggaga gccagccata atatataaat gtggacttac
     7681 ttgagtaata cctgaaaccc agtccccttt tttgattgct gcagacatgg atcgatcaaa
     7741 gctagtaatt tgatacgttg atccaatgtt ggaagtagta tttctttgtt ggtcataatc
     7801 aattagcaac acgtcttttt caaaaagttg actagaaaca atcgctaata aatcattgtc
     7861 tgtagtctta ccaatgccgc cttttctacc tgtaagcatt acaacttttc ctagtttatc
     7921 tgatgtttta aatgcagtcc gtaagttttc catagttccc tccaatttcc tatactaaat
     7981 atatttagta tacttcatat acttaatata ttcgatatat ctaatatact ccaaattgat
     8041 aagaattcag actttataag gaatatagtg gatatactaa atatatttgc tatattcagt
     8101 atatcagata tattcaaaat gtcaaaatat atttgtgcgt tttgcgttga caatttagag
     8161 tgaaaagagg taaacttaat tctatagaaa ccacagataa ttcactattt acaaagtagc
     8221 aaaagcagtg gtactcttta aacagaaaaa ttacataaaa aaaagagacg gaaataattg
     8281 attttagcag aatcaattat ttctgaatca catggttagg acatgtgttc acgctcgtct
     8341 caagaatatg taagtagcta ccaactactt atattaaaag ttgatcggat accttttccg
     8401 attgccttta ttctaccaaa aaaaggcgag caactcaaca gaagaacgtt tatttagtgt
     8461 acttaaatta aatattctta aacactgaag agagaacaca tactatggct gagattaaag
     8521 ctaaactgtg ttctcttttt gtttgagaaa ggacgttaca atcgatgttg agcgaaattt
     8581 attcagctat tcttaaaaac ggcttacgta catacaaata tcgaaacagc accatgaaac
     8641 ctgcaggtca tattgattcc agtaggagtg gtgctatctt tgcgtaccgt agcaagcaat
     8701 taatgaatgt tgggcgtggt atggtcatta cttcggaaga agctatttta gagaacgaaa
     8761 agaaactaac gcattggaca cctaatacct atcgctttgg tacttatgcg gatgattatc
     8821 gaacagtggt taaaggtcat tctgagaaaa acttaagtca aatcaacaca tttgtagttg
     8881 atatcgattc aaaagagaac catcaaggcg aaattatttt agcctgttta gatcaagtgg
     8941 gctacatgcc aacgctaatt ttagaatcag atcatggtta tcaagtttat tttgtactaa
     9001 agacaccagg ctatgtcaca aagaaaagca atttcaaggt gatcgatgta gcaaaaaaaa
     9061 tttcaaaaac aattcgtcta cagttggctg aaaaattgtc cggagtggat ctaggatgta
     9121 accacttcgg aattgctcga ttcccacaag aaaataatat tgtttttaaa gaaatgaact
     9181 atcagtattc ttttgctgac tggattcaat ggtcgatgaa gcttgaatca gatcaaaaaa
     9241 caaaagaaga tcgagaacga aaactaattg tctttcctga gaaaaaagaa attcgtcaag
     9301 tagatgaacc gtggttcgat atgttacttc ataaagcaaa catcgtcggc ggagaaggac
     9361 gtcttggtcg aaataatgtg attttcacgc tttctttagc ttattactct tcaggttatg
     9421 cattggatac ttgcgaatac aatatgttca cattcaacga acggttacag gaaccgctat
     9481 ctgaagcaga attagtaaag attgtacgta gtgcttattc tggtaattat caagcagcaa
     9541 gcagagaatt cattattgaa ttgtgccagc aatgggtttc accaacctta aaaaataatg
     9601 atctgttcat tcaacgacgt ggctggtgga aatttaaaaa gccacgagat caaagaaaat
     9661 atagtcataa aaatgaatgg aaagaagatc tattggctta tctaagcgaa aaaagtcttg
     9721 ctagtgagcc ttatttgaac ctgtcaaaaa aagaattggc ttcacaacta acgatgccca
     9781 agcgaacact tgataagatc ttaaatgagt tacgagagga gaataaagtc ttctacaagg
     9841 taacacgagg aagaaatggc ggaatgatca ttgcttcagt caaaacgttg ttcgcgaggg
     9901 ttattcaact aagtaaagaa aagagactag attattcaac aaggatcaca gaggtatttg
     9961 gactcaacga gagcttagta gaagagacat ttagacaatt atcaaccccc ttgaaccctc
    10021 ttaaagaagt gaatcttttt gaagtagata caggttgaaa aataaaaggt gcaaattgcc
    10081 ttatacaata tatctatgat acttctgtag gtgttgctcc ctttgcctag ctacgtgtag
    10141 gtggtatact tataactgcg tatgcagtct tatgtatcat ggaggaagtt gtatgtcgtt
    10201 aaaaaattat gtctattcac atcctgttaa tgtgtttatc attggtcgtt tgggattatc
    10261 tgtggaagtg ttctgtgagc tttatggttt taagcagggg actttgtctt cttgggttac
    10321 cagggaaaaa acagttgctt ctttgccgat tgagtttctt catgggttgt ccttagcttc
    10381 tggggagact atggatcagg tatatgattg tttgtgtgtg ttagagcagg agtatattga
    10441 gtataaaata gctaacgagt taagaaaaag gaagaagtat atccagtagt agtttttatt
    10501 tacttaaaaa attggttcat tgagcaacct atcgctgcta aagtagcaaa ggaaaacgtt
    10561 aaaggaaaga atttagggaa gaaatcgaaa tgaaatcgga cgactggatt gaacacacct
    10621 ggcttcctct gaaaagaaat agcaaacgaa agaaattttg ggtattgcaa ttatggccat
    10681 taggaaaact ttgtagttac ggggcacgac ttattcttga tttaaccgtt tactcgattg
    10741 gagtatttgg aacggcttat tacttgataa atgatcccaa taggattgca gcatcagaca
    10801 tttttacagt gctaatgacg ttgatttttg tcatgctatt gtctattttt actcaattag
    10861 tcatgcaatt taccaggcaa aaattaacag caggaaaact tttcaaaagc ctattcgatt
    10921 taattgttgt aaatgcaatt ctagcgactt taataaaaca aattgaacaa tctggaagaa
    10981 caacaaaagg agtgaaggat tttttattga cgtttattca ctttgtaaat ggacacatgt
    11041 atttgtttga agtgggtatt attctctttt ttgtcgggta tgtatccacg aaacttatta
    11101 aacgttcaat tgaaaaagaa attgaaattg acctgattcc gacacttctt ggttatgagt
    11161 acaatgttga ttttggaaga tatgacgaat tgatcaatac ggatatcgtt cacacgagta
    11221 tccatgaatc tactgttaag ggcatcagat ctattttaaa aaatggccag gaaatgaaag
    11281 caatagatcg aagaaaagag atctacaatt tttatgaagt cgaagcaagc ctacgatatg
    11341 gcatcggaaa attgtggtta gatggaagta atattcgtca aaacaaacca tacatttttt
    11401 ggaacagtag tgatttagaa cttccaatga aagataaata attatggaga atcgtttgaa
    11461 aatgattcct ctatacagga ttgtgcttat agttggcatg gagttaaaaa ccttaaagaa
    11521 ggagcagtta ttcaaagtga aagaacgtca taatcagtta ctatgtagta aaacgggtac
    11581 gatgaacatt gaataccgaa cagaatattt agaattaacg aatcaaactg attttttgtt
    11641 gattcgaaag caacaagagc aagaaaaaaa ttaatggcta cttatagcca attgattgat
    11701 gaatgggaac aattcaagga atctaaaatt ccagaacgtc tctaaaagcc tttatttgta
    11761 aagagcataa ggaaacgtgg gaacactttt taaaaaaagt gttccaatag gctgtgccta
    11821 ttacgtttct caaaaataaa tgtgggaaca aaatatttaa aaataggata gtgaaaggat
    11881 agtgaaggat agtaaaagga gggtagtagg atagcaaaaa ggataggctc cttttcgcta
    11941 tcctttttaa attggaggaa ttaatatgga agtaagaata agaaatgtgg atgagaaaat
    12001 cgtaagagaa attgatcgaa gatgtgacga a
//
LOCUS       DAYYEF010000073        11872 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000073 DAYYEF010000000
VERSION     DAYYEF010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11872
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.076"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..138)
                     /locus_tag="ACHA1B_002450"
     CDS             complement(<1..138)
                     /locus_tag="ACHA1B_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HFM8703181.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
     gene            complement(369..1475)
                     /locus_tag="ACHA1B_002451"
     CDS             complement(369..1475)
                     /locus_tag="ACHA1B_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFM8703182.1"
                     /translation="MIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLSWSVIFLAR
                     SVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQFQPSELANL
                     FLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIAWVIFWAAA
                     VPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDSFIDSHGAG
                     YQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIGALCVLFLL
                     FSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGVPLPFVSYG
                     GTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     regulatory      complement(1649..1815)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as
                     a genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
     gene            complement(2040..2246)
                     /locus_tag="ACHA1B_002452"
     CDS             complement(2040..2246)
                     /locus_tag="ACHA1B_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703183.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2262..2876)
                     /locus_tag="ACHA1B_002453"
     CDS             complement(2262..2876)
                     /locus_tag="ACHA1B_002453"
                     /EC_number="1.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA];
                     GO_function: GO:0016646 - oxidoreductase activity, acting
                     on the CH-NH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HFM8703184.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(3023..3706)
                     /locus_tag="ACHA1B_002454"
     CDS             complement(3023..3706)
                     /locus_tag="ACHA1B_002454"
                     /EC_number="5.1.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009385 - N-acylmannosamine-6-phosphate
                     2-epimerase activity [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA];
                     GO_process: GO:0006051 - N-acetylmannosamine metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019262 - N-acetylneuraminate catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HFM8703185.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3815..4273)
                     /locus_tag="ACHA1B_002455"
     CDS             complement(3815..4273)
                     /locus_tag="ACHA1B_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HFM8703186.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4357..6120)
                     /locus_tag="ACHA1B_002456"
     CDS             complement(4357..6120)
                     /locus_tag="ACHA1B_002456"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA];
                     GO_process: GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HFM8703187.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6341..7801)
                     /locus_tag="ACHA1B_002457"
     CDS             complement(6341..7801)
                     /locus_tag="ACHA1B_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703188.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(8009..8935)
                     /gene="glsA"
                     /locus_tag="ACHA1B_002458"
     CDS             complement(8009..8935)
                     /gene="glsA"
                     /locus_tag="ACHA1B_002458"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004359 - glutaminase activity [Evidence
                     IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HFM8703189.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8958..10385)
                     /locus_tag="ACHA1B_002459"
     CDS             complement(8958..10385)
                     /locus_tag="ACHA1B_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFM8703190.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10416..11630)
                     /locus_tag="ACHA1B_002460"
     CDS             complement(10416..11630)
                     /locus_tag="ACHA1B_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008519 - ammonium channel activity
                     [Evidence IEA];
                     GO_process: GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HFM8703191.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         3589 a         2441 c         1958 g         3884 t
ORIGIN      
        1 cttcagttga tcagtatttc ttcggttttt aatcttatct ggtacacaat tgtggtatat
       61 gttagaaaca gttctcataa tttccttgaa tgttataaaa gtatctgtat aatgttcagt
      121 atattttgat gaacgcatat gtagtcctca tttcttggga gttttgagac tactatatgc
      181 gtttttttgt tgatttacca acatgtttag acattttcct ctaggaaaaa attaactagc
      241 accacgggta taatatgatt ttttgagata ctttcattgc gaattcctct ttctaaaaga
      301 acctctcgct tgaaaaataa aagattgtac tttatgataa ttcaaactga gagtttctca
      361 gtttctcttt attgtttttc aggtcgatag agcgccaact cttcggcctg tatctttgaa
      421 gaaatattca acgtgattcc gattcctaaa gaaaggatca gataacttgt tcctccgtag
      481 ctaacaaatg gcaatggcac accagtcatt ggcatcagcc ccgcgatact tcccacgttc
      541 attatcgtct gaacgaatag caaagttccg aatcctaaaa gaaacaatcc agcttgctga
      601 tttttacagc gactgcttaa acaaaagatt ctcatgcata atgagaacaa taagaaaagc
      661 acacacaatg caccgattag cccaagctct tctgtaataa tcgaaaaaat aaaatctgtt
      721 tctgtctctg gaagataccc tttttttgtg atactatttc ctaatccccg cccaaatatg
      781 ccaccattat atagtgcata aaacgaatgg gtcatttgat agcccgcacc atgactatcg
      841 ataaaagaat ctcttaaagt cgcgatcctt tcataagcat gattaaacat ctgtggaagc
      901 caacctttat ttcctaaata taataccccg cctgctgctc caatcagcaa tgcagaaaaa
      961 gtaacgatta gatagatccc ttttttaaat ggaaccgccg ctgcccaaaa tatgacccac
     1021 gcaatcgaaa ggatcatcaa tgctccagca atctttggct gaaataaaat cagaaaagtt
     1081 atacctactg taatcaggaa tggttttttt agatcttttg ggctactatt tccgtcacga
     1141 aaaaaccagc ttaaataaaa aatcaaaaaa agatttgcca gttcagaagg ctggaattga
     1201 atgccaaaca gagagatcca acgttgtgcg ccgttgacag tgacaccgaa tatccctatt
     1261 cttactaata ctaaaaagaa aatcgataag gctaaaccgt atcctgctat tttagggtga
     1321 agtaaatagt gtagtttgac tgaacgagct aagaagatca cgctccaact caaaaatatg
     1381 aaaattagtt gacgcaataa tagacttttt gtattttcat cggcttgcaa taaacgataa
     1441 gaactggcac tgtatacttc taaaagaccg atcatggaca aagtcaaata aggacccaaa
     1501 atccaccaat cgatcttttt tcaccgcatc tcctcctcac acagcaatcc acttgtcagg
     1561 tgaggagcga gtttgtctca tcaaataagt cagtcacaaa aatataaaga aaaggtcaga
     1621 aaccttttcg aacaagaatt ctgacctagc atcatctcat cgtccgagtt ttagcactat
     1681 acaacgtaaa gaaaacattc ttagctattg gaaaaagcct taatccaaca gtttctgttt
     1741 tacccattgg cgactttcga cgtttctggg caacagccta tgtttgtata ggagcctcac
     1801 ctaacaaggt tattactata ttctatttac gagttcatga tagacttttc ctaatgatta
     1861 ggcaatggaa tttgaaatga aatagtgaaa tttaacaatc tttaatattt tttagaaaaa
     1921 aataacaaat aagttgaaag aatcccgttg caaattcttt cagttgcacc aggattcttt
     1981 gataattttt tagttttatg tgttttttta tatgtttttt cacttttcgg aataaatatt
     2041 tatttgttaa agtaattaaa caatccgcta atcgtttgat ctggcatttc tatttcctta
     2101 ccatctaaag taacagtagt aacgacaaaa tggtcttgca atggcggaac ttctaagtac
     2161 tgcccttgca gaaaatcatt cactgtttca tattcttttt tcatttcttt tgaatctgtc
     2221 gatggtttat agcttatttt taacataact agtgctcctt tttattcggg acgtgcaatc
     2281 gtgaaaattt ctcctattgc tgcataatca tttcctgcca aacggcttac agcattcaat
     2341 tttcttggat cgatccttcc tgtcttatca tcatagactg tttcatttaa atgatatttc
     2401 tgtacttcta gcaaaaataa atcagctgtt actttatttt tattccgtat ctcgacatgt
     2461 tcatataagg atgtttcaaa acgaactttt gcttctgtca atgctggtac tgaaatgatt
     2521 actgaatcag ttaaagtcaa gtcagtcagg tacagttcgc tttcctcatt aggcagattg
     2581 gctgctgttt tatttacttc ttctacgttg tcctcatcaa ggatatggat aacagcttct
     2641 cttgtctcaa gaatattctt tgctgtgtct tttactgcat cttgttttct ctggatcgcc
     2701 aaggataaga tgggtcgatt cgaactgacg atattgaagt aactgaaggg tgcgatattc
     2761 actatatctt ttgctgattt agtcgttact actgctactg gtctagggat gactgaacca
     2821 atcagcaact tgtaattttc acgttctgtc aattctgaag gactccgttc aaacatggtt
     2881 tcgccttctt tctataaaat tcgttaaaaa gcagatcttg aagacaaaat gaaaagtaat
     2941 gcttttttca tcttcttaga atctgcttta aactatctat caatttttct tttttgtcaa
     3001 gaatctgtgc cgtgcgtgtt ttttagttat ttgctttact tgcggcttcg acatatcttt
     3061 tagtgatcaa ttgcggacgg gtgataatag atccaactac gactgaaaaa gcacctaatt
     3121 catatgcttt ctctacttgt tcaggagagt cagtatgtcc ttccataatt actgggatat
     3181 cgacttgttc tatgatttga ttcaataaat caaaatcagg tgtctgcgtc tttcgtgaat
     3241 attctgtata gcctgctaaa gtcgtagaca aaagatcaaa accatcttct tgcgcttgaa
     3301 gcgcttcctc aaaagtcgaa atatctgcca tagctaaccg accgtgttcg tgaatcattt
     3361 ggacaagttc agcagttgtt ttttctgtcg gacgtttacg agaagttgca tccagtgcaa
     3421 tgatttctgc ttgcgtctcc aaaagttctt ccacttcttt ttctgtcgca gtaataaaca
     3481 cttctgaccc atcgtaatct cttttgataa tccctattac cggtaaatca acgattcgct
     3541 tgatttcatt gatatcttct gtcgtatttg ctcgaatacc aactgctccg ccttcttttg
     3601 cagccaaagc cattctcccc ataataaaag aactgtgtag cggctcgttt tccaaagctt
     3661 gacaagaaac gacgactccg cctttgattt gttccagtgt atccacaata tctcctccag
     3721 taatgttata taaaaataca gcttcatata aaaatgtaac ccttttctat tcaggagaca
     3781 ataatgagct atttctttca gcagaccttt cttactaaaa gaaaattact tcaaattctt
     3841 cgtatacgac cagcttctct tctgtaaatt ctatgttcaa cgcttcttta taagcatgtt
     3901 taaaaaactc agcatggact ttccgccaat aagctaatgt ccgatcccct tctccttctt
     3961 tccaagcatg ctctttcgtg acttcactaa aaggcaagat ggtcacattt atatttttga
     4021 tgatacaaac tggttcattt tttccattca ggaccacgtc taattgacca acttttggta
     4081 aaggctcatt ctcttgttta tacagatcgt aaccacttga tgtaccagtc tttatctttt
     4141 ttacaactag ttcgctcaac tcgtctgcca ttttttctgt atccccaaat gaaaagaaac
     4201 ctaatttttc tgattgataa ctaggatatt tttcttggaa ctttttgaca tattcttcta
     4261 cttgctgata cataacatcc acccctttgc tttttataat gaaaaaacca tccagatact
     4321 agtataaaca attatctgga tggtgagcat aatgaattat tgaatattca agacacgcag
     4381 actatcttca acgatttgtt ttggtgttaa atgataacgt tcataaagct gccctacagg
     4441 aacgctatcc gtgaattctt tctctgcacc aaaatttaat acgttcattg aagaatcacc
     4501 ataataacga ctgatatttt cgccaaatcc tcctgacaaa ctaccatctt ctaatgtgat
     4561 gactaattcg tgtgtttctt ttaatttatc taatgtttct acgtcatttt ctgtgatcgt
     4621 tcctggattg atcaacgttg cttcgattcc tttttttcta aaagctttta ctgtttcttt
     4681 tcctaattca agaaaaccgc ctaaagctaa aattgctact tttcctccat tatttactgt
     4741 ttgataggct ggaatactat aatcatttgc gatagctgta ccatgttcta caccatgtgt
     4801 aggaattcgg attgctacag gctgcgctgt ttgttcgaac gcccaatcta gcatagagat
     4861 catatcctct tttgttgctg gagcaagata tttgatgttc gggatacttg ataagtaagg
     4921 aatgtcaaat gttccttggt gtgttcggtc actagctgag atcgttccgc caccgactaa
     4981 aataatcact ggattctcgt tgatcgctaa atcatgtgat aattgatcat atgcccgttg
     5041 caagaaagta cttgattgga agacgactgg acgtactccc tgagaagcca aagcagaagc
     5101 gaaagtgata gagtgctgtt cagcgatccc cacgtcaaaa taatgatctg gatgtttttc
     5161 ttggaatgtt ttcagtccaa aggcgcctgg tatcgctgca ttgactgcgg caataggagc
     5221 tgtacttgtt tgcattttct tatccaaata atccatgatg atcatattaa atgtttctcc
     5281 agaagttact tgctttgcct ccccggtgga cagatcaaat ggtacatgcc aatgatattt
     5341 cattttatta tcgattgccg gctgataacc gcgacctttt tccgtatgga cgtgaagtac
     5401 aatcggatga tcaatatctt ttacttcttc aaataaacgg atcaccgttt ccagatcgtt
     5461 tccattatcc acgtaacgat aatcaaatcc cattgcttta aataggttat tgctgctttt
     5521 accgttggtt tgacgaagct cagctaagtt tttatataaa ctgccatgat tctcatcaat
     5581 agacatctca ttatcgttta ctaatacgat tagattggat tgtaaaacac caccattgtt
     5641 caatccttca aaagctaagc caccacttag ggagccgtca ccgataaatg ctaccacatt
     5701 tcctgattct ttcttcagat ctctcgcttt agctaaacct gttgctaagc tgatagatgt
     5761 agatgtgtgc cccactgtaa aatagtcatg tttactttca tgttggttgg aatatccgct
     5821 cacttcacgg taatgtcctt tttcaaaacc attttttcga ccagttaaaa gcttatgacc
     5881 ataagactga tgggaaacat cccaaacgat tttatccttt ggtgaatcaa atacataatg
     5941 aaacgcaatc gttaattcta ctacacctag attcggacca acgtgcccac ctacatcgct
     6001 gtccttttgc aagatttttt ggcgcatctc ttctgccaac tgtttcattt cctcaacaga
     6061 taattttttg acatctgcgg ggctattgat tgcatccaat acatgtaata ctgtactcat
     6121 aatacattct ctcctccgta ctatcttctt ttaatgaaaa tagatttgtt acactttatc
     6181 tattctacta cttagagttg actctaagtc aatagcattt taaaaaaatt tcagagaaag
     6241 cttgttatat aagtagatct tcgcacgaat caggactcaa ataaaaacct tctacagaca
     6301 attaaaaagc tttgtagaag gtctcctaat taaggtctca tcaagaaata tgttttttta
     6361 ataggtgaag ttcctgagca atatgataca aatggatgtt tgcacctttt aatgagattg
     6421 gatagatctt tgtcttttca gtttctaatc cattttgata gctagcagca tcgcacaaaa
     6481 ccactctttt tttcgcacat agacattcat caggcaattc ttctaatgaa cgaaataaaa
     6541 taggatttat ttcagcgatg ccttcttccg catacaaatg aaattgggtt cgataaaaaa
     6601 attgtttgac tgaactttct gaaacaacaa aaatttctat ttcctgtctc cccgcttgtt
     6661 cactgttgat caaagaaaga cttttgacga attttcgaat gaaattttca ttccatctta
     6721 gttggatttg atttttcttt ttccactctt ccaatatttc tacaattttt ccgtacagaa
     6781 gttgttcttt ttctgataga agatagatcc tttccggtaa aaatacttgt ccatctgccc
     6841 acaacgtacg gacaaattgt aaaaaggatt gcttgaaaat aaaattttct gcatcgtcga
     6901 tttcagcgat actaataatc tgtaaaatca attcattcag tgataggtca ttgagaacaa
     6961 aatttttata aacaacttcg aaatcttttc ttaacagctc catgttctca ttggtataat
     7021 ttctactgtt gaacaaagaa aaaatataat agacatcttc ttcttgtaag tctagaattc
     7081 ctttttgctc ttccaatcct tgacagacta attgaaataa cggcttcgtt tctgcgcttt
     7141 tcttatcttc ttctttcagt ccaaggggaa atgcctttct tccgattgcg atctctattc
     7201 ctcgtatgat aaaggacttt tcatcttccg aatatcttct tttaaaaaaa tgagtctcta
     7261 cataatcaat caactcgtta caagcttctt ctacatacgg atttttattt tcatagcctt
     7321 cccaattgac ataacgtact aaagctagca agatgttccg cgagtcaaat tctgggataa
     7381 tgatttcttt atttttcaaa taatcatttt ctttaaaaaa atccaatacg atttttttga
     7441 ttgtatatac tttgctcaaa gaaataaatt caagatcagc cagttctgta ctcgtgaata
     7501 taccattaaa ataataactt aaaaacttta aaaaataaga ttgaccgtac agaaactgtg
     7561 tgagctcaga aagagcaata ccatgtttga atacgagttt atacttatgc ttctctctta
     7621 cttgttcttt tatacaatat tctagacact cggctagact ttctagatcg tgaaggatcg
     7681 ttggtgtagt cacccttaga gaaatagctg tttgttcgat gtctatttct tggaattcaa
     7741 ataattgttc acacagatac acttttctaa atatatttcg ctcgatgtaa ttttccagca
     7801 ttcctgatac acgcctccag tttttcttat gattttattt aatcatatct gtaaatcgta
     7861 tttttgtttc ctttttattt agaaaagccc tttcaaaaac caataaaaaa agaaactggg
     7921 acaaaagtca aacaagctca caatttcagc ctcattgtag gtagctttga gccgtttgga
     7981 cttttacccc agcctctttc aagaatggtt attcaaagat gtcagcgtct agttctttga
     8041 ctacatcttt caacaattgg ataccagctg cgctgttacc aaatggatct agtgccgggc
     8101 tgaagacacc tatgccgtaa cgatttggca cagctgccat caacccgccg cctacaccgc
     8161 tttttgcagg tacaccaaca tggacggaaa actctcctga ttcatcatac aaaccagcag
     8221 ttgtcataat tgatttgacg attgtagcac tttcttcagt aatgatttgt ttgccattcc
     8281 aaggagcaat tcctttattt gccagcacag cagctaattt tgctatgcct gtagcggtga
     8341 cattgaggga gcattgtctg aaataagcat cgagtatctc cggtacgtct ccttcgatca
     8401 tttgattacc tttcatatag taagcaagag agcgattgat atcacctgtt cttgattcag
     8461 aatgatagat ttcttcattc aatgtgatat taggatcatc acagatctct ttcataaatg
     8521 acaagattcg ctcaaatttt tcatctgcat ctttaccggc aatcaacgag gttgttgcaa
     8581 tcgctcctgc attaacaaaa ggattcattg gatgtttgcg atgattgatt tccatattca
     8641 tgatagaatt gaaggcaaaa ccggttggtt ccgtgttgat tgtttgaaag actttttcta
     8701 ttccgttgtc tttgattgct aataacaata cgggaacttt tgacatgctt tcgatggcaa
     8761 agcgcacatc ggcgtctcct ccctcaatca gttgttttgt atccaaatca taaatcgcca
     8821 tacctaattg tttgggatcc acttcagcta atgctggaat gtaatccgcc acttgtcctg
     8881 tttgataata gtggaaattt tttccaatca attgttctaa ttcttttact tccatttgaa
     8941 taaccagctt tcatttttta tttttctgca tgctggaatt tatgacggca tgcgtagatc
     9001 gtaaatggaa taactaagac gataagataa gaaacaatca gaatcgtttc ataaatccca
     9061 tgctgtccag ctgcgatact agcaggtgga acaaatgaga tacaaaaagc aaaaagtgaa
     9121 gtcaaaagac ctaaacaagc aacgattact tttacaactt ttccgcctgg aacctgatag
     9181 gctctttcaa gactgtcatc tttaaaaacc agcttcaaat agcccgcgaa aaacataaag
     9241 tacaacatca ggtagattac aacagtcaat gacatcgctg caagaaatga aagattattc
     9301 cccccgccgc ttaatgtaaa gacggctgcc cagattgttg caacgatccc atttgcgatc
     9361 atcaaatgag caggaacacc gtgtgtgttt tcttttgcaa aatattcagg aagtaatcct
     9421 tcttctgctg ctacgtgaag tgcttttgaa ggagaggtta cccaagaagc aatttctccg
     9481 atgacaccta aacaaacaag aatcgcaaga attttcgcaa tccatgcaag atttggatca
     9541 atgtgtctta ataggaattc taacgattga atcacccctg tattaagaga caaaccatgt
     9601 tgaggtactg tagtagcgac ggtcaatccg ccaaaagtat ctaaaatgat tgccagaata
     9661 accaatacaa acattgctaa tggataatcc tttttagggt tttccatttc atttgcatga
     9721 ctggcagatg tttctacgcc catatatgct aaaataaagg aaacaaaaac aaccagcgta
     9781 ggcaatttcg aaaaatcagg aatcaatgtt ttcatagaca gtatcgtttg tagtggagcg
     9841 cctgaagcga cataatggat ccctaagcca aacaagacta atgctggcaa caagatacca
     9901 gctacaaaac cgatccgagc aatcaatgaa gtgtatttgg ttccttttaa ctgtgagagt
     9961 aaaatagccc agaaaataat caataggatt gccaatttca gatatttatt gttttgtata
    10021 gcaccaatac ccgttgcata ggataatgca ccagttaaga aatacagcat ggtcaagtag
    10081 ccaactgtta tctcaaacca ttggaaaaag attgcggcaa aaccgaatcg ttttcccaat
    10141 gtgcgactga cccaagtata gacaccgcct ttttcccatc ctttcaccgt tgccatctct
    10201 gctgcgcaca atgccacagg gataaaccat agcaaaccgc ctaataacaa gaaaaatact
    10261 aagctgaagc ctgaggtcgc gaatgtggga tattcatata atgaaacgac cattgagatg
    10321 gtcatagcca aaaagccaaa gaacgttaat ttttttgcag gaattttcgt tttgctttgt
    10381 tgcatgaatc ttcctctttt ctatttgaat ttgtttcaat tgagtttgtt gccaaagaag
    10441 aaaaagtcca atccttcttc ttgttcttct tttgtagtag tgatcgttgt aaagtgcatc
    10501 gccgatttta aaatcactgt tgtcagcaca taggcataca cggcagtaat gatgacacca
    10561 atcacttgaa tccctaagaa gtaccagctg cttggattcg ttagtaaatg gctgttagat
    10621 gcaaagatcc ctatcagaat cgtacctgtg aatccgccca tgccatgaac accccacaca
    10681 tcaagtgcat catcccattg tttcttttta cgaaaatcaa cagcagcatg acagacgata
    10741 cccgcaatga tcccaatcag catggcactt tttgcttcta cataaccggc acaaggcgta
    10801 atggctgcca atccagcaac ggatcctgtt agtacgtcga caaaatcaaa gccatttcct
    10861 tttacttttg caatgatcag ccaagtaatc atcgcaaatg caagagcgat gaatgttgaa
    10921 ccaaatgcat tgactgcttg ttcatctgct cgaagtgcac caccggaatt aaaaccgaac
    10981 cagccaaacc aaagcagtcc tgtaccgata gcagctgcca taagactgct atgctgactt
    11041 ctttctccta aaggaatctt tctttgacca agtgtgagga tacatgctaa agagccgaat
    11101 ccagctgtcg tgtggatgac tgctccacca gcgaaatctc taaatcccat ctgatccaaa
    11161 aatccgccac cccatatcca gtggcaaaca gggaaataaa tcagcagatt ccaaaaaata
    11221 acaagtataa tatagccttt taaattcaat ctccctgcaa aagctcctgt catcaaagga
    11281 acggtaatca cgataaacat cagttggtaa agaaagaaca ttaaaaatgg aatcgttgca
    11341 ccatgaaaca tgttggggaa gcttgtaaca tgtctcatca aaaagaaatc tgccgggttt
    11401 ccaataacac cgccgatatc ccgtccaaag gccaatccga atccaccaaa tacccacata
    11461 atcgttgtta tcccaacgga gagaaaagat tgagacatga tcgttagtat attattcttc
    11521 cgtgctaatc cgccgtaaaa aaaagctaga ccaggagtca tcaggcaaac cattgctgta
    11581 cataaaatca tgaatgctgt atctcctgta ttgataggta atgtattcat ttttttcgcc
    11641 tcctttctac gattacgagt ataaaagaag gtgtagttgt ttttttcttc tgtttttttg
    11701 aattaatact tgcatttata aaagacagac aattaataaa agcttgatgt gttgtgctct
    11761 ttttcgtttt tcacacaaat aaagacaaaa aataaacggt cttcttttta tagaaaaccg
    11821 tttattttcg tcttttttta tttttaaaga tattttttca taaggaataa ag
//
LOCUS       DAYYEF010000074        11837 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000074 DAYYEF010000000
VERSION     DAYYEF010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11837
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.077"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(561..1601)
                     /locus_tag="ACHA1B_002461"
     CDS             complement(561..1601)
                     /locus_tag="ACHA1B_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFM8703192.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1950..2276)
                     /locus_tag="ACHA1B_002462"
     CDS             complement(1950..2276)
                     /locus_tag="ACHA1B_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703193.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2263..3051)
                     /locus_tag="ACHA1B_002463"
     CDS             complement(2263..3051)
                     /locus_tag="ACHA1B_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM8703194.1"
                     /translation="MARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVDIDPQG
                     NATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAEREFTQVG
                     SEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLKGLIKL
                     SETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKTYIRRT
                     ITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
     gene            complement(3419..3709)
                     /locus_tag="ACHA1B_002464"
     CDS             complement(3419..3709)
                     /locus_tag="ACHA1B_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HFM8703195.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(3845..4024)
                     /locus_tag="ACHA1B_002465"
     CDS             complement(3845..4024)
                     /locus_tag="ACHA1B_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703196.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(4021..4371)
                     /locus_tag="ACHA1B_002466"
     CDS             complement(4021..4371)
                     /locus_tag="ACHA1B_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703197.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(4364..5689)
                     /locus_tag="ACHA1B_002467"
     CDS             complement(4364..5689)
                     /locus_tag="ACHA1B_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HFM8703198.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            6139..6753
                     /locus_tag="ACHA1B_002468"
     CDS             6139..6753
                     /locus_tag="ACHA1B_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703199.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(6918..7160)
                     /locus_tag="ACHA1B_002469"
                     /pseudo
     CDS             complement(6918..7160)
                     /locus_tag="ACHA1B_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7364..8683)
                     /locus_tag="ACHA1B_002470"
     CDS             complement(7364..8683)
                     /locus_tag="ACHA1B_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HFM8703200.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            complement(8817..9425)
                     /locus_tag="ACHA1B_002471"
     CDS             complement(8817..9425)
                     /locus_tag="ACHA1B_002471"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703201.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSLNNSYF"
     gene            complement(10063..10320)
                     /locus_tag="ACHA1B_002472"
     CDS             complement(10063..10320)
                     /locus_tag="ACHA1B_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HFM8703202.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(10313..10582)
                     /locus_tag="ACHA1B_002473"
     CDS             complement(10313..10582)
                     /locus_tag="ACHA1B_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFM8703203.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(10713..10892)
                     /locus_tag="ACHA1B_002474"
     CDS             complement(10713..10892)
                     /locus_tag="ACHA1B_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703204.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            10990..11226
                     /locus_tag="ACHA1B_002475"
     CDS             10990..11226
                     /locus_tag="ACHA1B_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703205.1"
                     /translation="MKQNTSIAKNTTKFKCTAAAWRISISPTNRTNNRGMILFIWISF
                     FLLGYRVLPAYFAPPKRRGRLERLVRNKNHSLSY"
     gene            complement(11273..>11837)
                     /locus_tag="ACHA1B_002476"
     CDS             complement(11273..>11837)
                     /locus_tag="ACHA1B_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703206.1"
                     /translation="EQLYLESETSQTKVTVSHNRLDVYKRRPETVKKGTELLRLETEK
                     YIMNVYLERSELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATIDD
                     YYLVFTRFLTCGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYT
                     YDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT         3603 a         2163 c         1789 g         4282 t
ORIGIN      
        1 tccgttgcgg gtaataccgt aacactgaag ggcacgcatt aaggcgtcat cttaatgctt
       61 tcctgtagga cactgacgga gattaccagt ctcccgagcc ttacaggggc ctttcttttt
      121 tttgtatttt caattatcac aatttatcgt ccaaaagtgc agaacgaaaa tcaattcatc
      181 acaagcatat cagacaatta aatttaaaac aactaaaaat atacaaaaaa gtgtaattga
      241 atattagcag cactgcctga aaagaagtaa tatcaggctt ttcagcttgg ggaaataagt
      301 gaattacctc tcttcatgaa ttattataac tcaaaaaagc acatatgcaa acactagttc
      361 cctatttttt tgaatgaaaa ataactaaaa tatctaacga ttatgacttt aaaacctacg
      421 tttgtgattg ttttcataaa cttttaatct aaaaactccg gaataatagc tatttatttg
      481 taacatttgt aataaaatta aaatcataaa aaagttctaa tttaaaattg atcattttta
      541 tagtgatcgc tttttatcaa ctactctagc caattttccg tactaactgt tggtaattcg
      601 ttaaatgttt ctctttgttc gtttgcaagc tttgccgcaa tagctttttc gacaaaccaa
      661 ttttttacat aaacgaaaat tagattctgc aaattgttta ctttttcagt tttttgtttt
      721 tgataagctt tcagcaaagt catatataat cctttgtcag catcaattcc ataagattcc
      781 agttcttcat aaacaacaac tgtttgctct aattcttcag cttttttctt tgcattatga
      841 atagtttgga cggttttttg agcgtcttcg taagtactag aaaatgtttt tatcaagttt
      901 aatacatttt ctggtacaaa tgtatttata ctgtcctctt tcatgatgtc gacgaagtta
      961 tctagtaaaa cttgattttg taactgatca gtttcagtgt ctattatgtg tctattagtg
     1021 tctatagaat tagaatagaa tagattgtct gcgattttcg caattacggt tgagtccttg
     1081 atatgactgg attttgccgt atttgcgatt ttcgcaatta cggtggtatc attgatttct
     1141 cgcggttttg ccgtatttgc gattttcgca attacggtgg tatcagtatt gtcttcctct
     1201 tccatgattt taaagacgtc ttgattcgtt acttctggct tgcctaagta caataaatta
     1261 ggcatggatt caatcttacc gtcacgttta tttactcttc ctctcttctg tttcagaaga
     1321 cctgcttttt ctaattcctt tttgatttta gatactttac cttcgcggca ttgtaacaat
     1381 ttcattaatt cttcaactgt gaatatgaaa aatatattat catcagaatc tacccagtta
     1441 tttttgactg aataatcaaa tcgatcttta agtagcatat aagcaatttt tgcatcattt
     1501 gatagatcca tgtatttttc gttagtaaaa aataccttag gcatttgata atatttttca
     1561 cgataaattt cttttgattt gtaataatta aaatcattca tagccaatcc tctttctgta
     1621 ggatagcgtt ttgttcaaaa ctatgttaca atgaattaaa caaatatatc tatccactat
     1681 atatttttct actgctgata agtcgccaaa ctttgttaaa gcagtagtct ttttttatct
     1741 ttttttagtt taccttaaaa aataaattaa agcaaaccgc tctatttcaa ggtttaagct
     1801 catagtaact atatcacgat attacaataa tattatatca cgatatcgta atattacaat
     1861 atgaagataa gcgacttatc agctttgata ctactgattt ttataaaaaa aatatcacga
     1921 tattatgata tcgtgatatt gaatgtaaat taaattttat tttgtttctt tgctagttta
     1981 tatccttcaa tcaagtattc ttcaggtatg gactttaata gcgcatcttc tataacgtct
     2041 ggtttacttt tgtctgattc agcaatagtc gtccaatatt tgagtgctga cattagaatt
     2101 ggatttatac gaatgctatc tgctgttctt acactacttc cttgatcttt tatgacttta
     2161 cttatatttt tcttggttaa ttcgatttct tctacttctt ttgatttaaa attcttttta
     2221 tttttatttc ctagtaatct acttactgca gcttgactgc gattatcttc tgccatcaaa
     2281 atcaccaact tcttttaaat attcttctgt aaatgcttta tagtcatctt cagctgttga
     2341 gggtttatta aaattgatta gatctgatcc agcagcttgc gcttcgtcaa cggttattgt
     2401 cctacgaata taagttttga aaatttttgc accaatgact ctagaaattt cggttgctgc
     2461 agacgtcatt tctttagaaa tgttataacg cttattatac ttagtaaata gaactcctcg
     2521 tacttcaagc ttgtcgttcg tatattcttt taccgtttca atagtttcac ttaactttat
     2581 tagtcctttt aatgagaaat acgcagcttc aactggaatg ataatttcat cagaaacagt
     2641 aaatgcgttg actgtaagca ttcctaaact tggtggacaa tcaattataa tataatcata
     2701 gttgtccttg attggttgaa gtactctttt aagcctgtgt tcacttccta cttgagtaaa
     2761 ttccctctct gcagaagaaa gggctatgtc ggctggcaaa acatcaattc ctttatagtc
     2821 cagaatagca tctgtaatgt cagcctcccc ttttaatact tcataaattg taggttggtt
     2881 tgttccatct atatcgaaac ctacattatc tgtagcattt ccctgaggat caatgtccac
     2941 taaaagtaca tttttaccgt aaacaaattt caaacatgct gctaaattaa cgctagtcgt
     3001 agttttagaa actccacctt tttgattggc tactgacaat attcttgcca ttaaaatatc
     3061 ccccattcat cttatattat aatataatta tatcataata ttgtgatatt gcaatatcgt
     3121 atatgcatta tattgtaata ttgtgtgatt attttgtttt aaagatatat atcggttcgg
     3181 atataaagat tattcatatg ttattcgaaa ttaaaataat cactttttat tactttaaaa
     3241 ttttttatta atgataagaa atatgttttg cgagcagcaa ctagaataat ttaaacatta
     3301 ctaaactgtc tatattgtta ctaataattc ccttcttata gtgcattttc ttagaaaaaa
     3361 acaatattac gatatcatga tattaagata tcgtaatatt atacaattgt gattgatatt
     3421 atatatgttt ttttattttt ttatcatgtt taatcttgaa ggaatcatat tctttttcta
     3481 aagacaggag cttttcataa acatcagaca tgtttaaact agaggccagg cttaaatcat
     3541 aaacgaatga agcaggtaat gattttattc tacgttgtcg ggttatccag cttgcaaccg
     3601 ttccttgtgg gtaggcatat aactcacaaa attgttctac agtgattcct aaattcttga
     3661 taatgtaaac attgatcggg tgcgagtaaa caaatgtatt gatagacatg gtgcgtaagc
     3721 ctactttctt ttattattgc gtttgcaata atagtttaac acacgcatta ttctagtatc
     3781 tactcctatt tgtaaaaaca aaaaaggatt catagagata actctataga atccgtaaaa
     3841 taccttatat atataacggg aagatataaa acctaaaatt atgataacct gctgcagctt
     3901 ctacatagaa agagaagcgc tcaacaccaa cctcatttat caaacgttgg ccataacccc
     3961 aaatctcttc tgatagctga tcaaaggtta tatactttag ctcatattgc tggataatgt
     4021 tcattctaat cgactccatt tattatcctg gtaaaattcg atatgacgta tttcgtcgta
     4081 gtgaattttg tcttttccaa cgtagatccc cagctcatca ctacctaaga tcttgccaat
     4141 gatatcttct ggatagtatc cttcagcgtt tcgttcttct ttttgaatag atactgatct
     4201 attttttatg actgcagcgt tcaatacttc cgcaatctct tcagtcgtca tttgttcttt
     4261 tgctaaattt tgactggttc gttgttcatt gtcggcatca atttcttcag tatgatcaga
     4321 taaataaaac cctgcccact ttaaacgtcc acgatcattg taatcaatca tttttaattc
     4381 ccccatttcc gcccgcatga ccaccaacaa gtgtgcttct agtaatgctt ctagcgcctt
     4441 ctaacattga agaagcatgt acaatcgacg taaaaccata tttttgccga atcttgtcaa
     4501 taattttatc taaattttct tcgtcaattt gcttttgtgg atcactaaat aaatccagct
     4561 gaagcgaatc ggtgtacaca agcttgctat aggttattcc aacatgcctt acttcttgtc
     4621 cttcataata cttatcaaac aagaaaagac aataattctg caattccttt gtattatctg
     4681 tgatagggat cttcatctgg tgtgaaaacc ctggtctcgt ttctaagatc gacgtgccaa
     4741 tgtgtaaatg gacacaacct gttttacagt tatgctgcct aatgcgtatc gctacttgtt
     4801 ccgccatttc ttttaccacc agctcgattt catttcttct agtataatct cgtggtaaca
     4861 cttgtgaatt tccatatgat ttttcctttg tcggttctgg tgggattgct atatctgttc
     4921 gatcgatccc attagcatgg aagtacagct gtaagccaat cacacctagt ctattcttaa
     4981 tcgtataagg attccagtta gcaagatctc taatgctcat aatccccatc tgattgagtc
     5041 tttttttcat tcgagagcca attccccaaa agtccgtcat ttcaggaata ttccatactt
     5101 tttcaggaac gttttcgtac gtccattccg caacaaatcc ttcattatgc tttgcttcgt
     5161 tgtctaaggc tagtttagcc aaaaggggat tatctccgac acctactgta gcaatcaatc
     5221 ctagctcttc tttaatattc tcctggatca tttgagccag cttctttctc cgttgacttc
     5281 gtgttccttc agtcgtaaaa agattcagtg atcgggtcac ttttaagatt gattcatcga
     5341 tcgagtaaat cagtagatct tcatcagcca catatcttct gaaaatatta tttacctgca
     5401 tatttcgctt gatatatagg ttcatacgtg gtggaacaac gtgtagtgtt ttaggaaatg
     5461 gttgtggtaa gtcacgtggt ctactcacat ttgtaatacc ataccgcttt tttgcttcag
     5521 gagaagaagc taatatcaat cctgaaccag tattatcagc tcgactcata acaacaagtt
     5581 ctgttgttaa tggatctaaa tttctttcta tacattcgac acttgcgtaa aagcttttca
     5641 tatcgattaa aaagtaatca tttactggct cttttgaata atccatcata aataacactc
     5701 cattctttca cattatacaa acatatgttc gatattgtaa agaagaaata gctaaataca
     5761 taaaaaaaga agcataggta tgctatcacc ctgcttcttc ttttgatttg tatgatcaat
     5821 ttattctatc actttactaa ttaatttgaa aatctaataa aaactctcac tctaaaagag
     5881 tgagagactg caaattagag tacggacttt tttggagttc cgttctttaa tattaacaaa
     5941 tgaataaaat ccttacaaca tttgagaata agttatcagt agacacttac aaaaaattct
     6001 catactattt cctccatcat tagtttttgt ctatataagg tttaccctaa atagacactg
     6061 gtataacatt gaaaaatatg gcttcctcgt gtatgattag ggtgtatttt aaatagttgc
     6121 agaaagtagg taaaagtttt gagagttgca tacatacgtg tctcatcgat cgatcaaaat
     6181 gaacaacgcc agattgaaga aatgaaaaaa ttcggtgcag agagaatttt catcgagaaa
     6241 caatctggcg caacgattac tcatcgacct gttttccaag aagcattaga ttacgtccga
     6301 gatcaagata tttttattgt ggaagctatt gatcgacttg gaagaaatta tgacgagatc
     6361 atcgcttcag tcaattactt gaagaagaaa aatgtgaagc tgatcattac tagtttaccg
     6421 atcatggctg aagcaattgg caatcctctc ctggataaat tcattaagga tctgatcatc
     6481 caaattttgg ccatgatcgc tgaacaagaa cggactgaat cgaaacgtcg ccaggcacaa
     6541 ggaattaaga tcgcaaaagc aaacggcgtc tacaaagggc ggcccaaatt atacagtgca
     6601 gacgcaaaag atccccaacg tcgccttgtt tacaaaagca tcgttgaaga tcttaaaaat
     6661 ggtgttgcga ttgctaagat tgctaaagac tacaatgtta cgagacaaac cgtgtataga
     6721 ataaaaaaag acagcatggt caatgacaaa tagttgatca tgctgctttt attatcttct
     6781 catctttaat ttcctacata taattactat ctataaaatt aagtcttact cagaacagat
     6841 aaagcataaa attccaacaa accatttttt acttaactaa ataaagagtc tgttaatata
     6901 atcttcactt atttacgtta atcccctact gtatttgttg gttccttatc tatattttct
     6961 acaaaatcct tattatcttg tgatttagct tcgtataatt ctttgtatgt cgacacattg
     7021 gttatactaa ttcctatagc tagttcttga gactctactt ttctctctag ctcctttgac
     7081 aaagtgattt gagatttatt tggttccgtt ggagtcaatt ctatagattc ttcataaaaa
     7141 tctctataca taaagctatc cctgaataat tcatagcttt aattctttgg cacattttat
     7201 tgaaatatgt atcactaata tccctatcaa ctgattttga ctaaaaagtt acttcaaaca
     7261 ttcactgttc aaaaatattg aggaataaat tttgggtgta aggcattttg agcatacttc
     7321 tccctggata acttcccagt aaaaaaatcg ttagattgtt ggattagatc cattgactgg
     7381 ctcgcctcag gcgagcaaag accctgtaga attcattctg atacacatga taactagata
     7441 atttgagata gactcgtcta cccgtttgga ctaatttccc agcaactttc agaaacttca
     7501 atcgaataga atgaatggtc attccctttt ggacttcttc aaagccaatc gttcttaaga
     7561 agttgactaa gttgtaagct atcaagctga gcatcattcg gacatgattc tccaaaaagc
     7621 gaggactgtc tgttttgtca aagtaaaagc cagctttcgc ttctttaatg aagttctcca
     7681 ttgtgccacg tttggcatag atagaaaaga tggtatcagg agaaacattt tctgatagat
     7741 tcgtcacgat aaattcatgt cgaaagagta gttcgcccgc ttcacgtgtt gagcgtatac
     7801 acacgcgacg actttgtgac caggattgtg cttgataagt ggtcgagaag tactgaactt
     7861 ctcgttcttc ccacttttga ttatcgccat aaagtactga tttctcagct atttgaccta
     7921 gtctacgatt attcttcagt cgaataacat aatgactctt ttttgattca cacgaatcat
     7981 acacaccagg tgtagcgaac ccgctgtctc cacgaaccaa gatgtcagtg tttggtagag
     8041 agtgattata gtgctctaat aaaggtgtga gaaactcctt tacgcctttt gatgtatatt
     8101 gatttcctga acgtagttca gcttttaaga agtcaccagt caatccgtca aaagctacca
     8161 atggatggta accataggtt tggtagtgtg tattataatt cgtttgttct tggtgaccaa
     8221 atgtatctga atgggtcgaa tctaaatcaa tgattaattc cgtatcatta cggatgaggc
     8281 gtgctttatc gataagttct tggttcaaag cttgaagttc atggatattc tcctcagata
     8341 gtcgatctaa aaatcgggaa agtgaagatt gagaagcgag ttctttccta tctaaaacag
     8401 ctttaaacac aggatcttgt ctcaggagat tagctgcaga atcagctgag taaccagcaa
     8461 ttaattgcat aatgaactgc tcaagtatgg ataagttgtc atgagtaaaa tacgctcgtt
     8521 cgtcttcaat gtgaatgtgt tgcttagcca gttcagaaaa accaaagatg ttcatcagct
     8581 ctttcactag gacgagaccc gaatcactcg ataattgacc acctgtatga gaaatagtga
     8641 tatttgaatt gaattttact tggtttttgt gtaagctagt catgaaaaga actcctttct
     8701 tttggttggt ttagtcactt taaccatagc agaaaggggt tcttttttca tcacttaacg
     8761 ggtgaagatg aaaaagtaat tgtaagctgc cgtgaggcag tttcacatgg ttttaattaa
     8821 aagtatgaat tattcaggct atcattaatt ttataaaaaa aattaaatgt ttttagcact
     8881 gccatataac attcaaaaca ttcttctata gttggtttac ttccttgagg agaatgaacc
     8941 aatttattac gtttttctat gaaattttta atttcctttc ttatttcttt cggaaactca
     9001 atattaaagt accctttaaa catgctccct aataatttgt ctacaggggg agattgtaaa
     9061 ttctcaaata ttagagttaa atcaggtttc tcttgttgat aaaattcctt tacccctatt
     9121 tcacaggctg taattatcga aataaaccta tctctagtat ttgatatatt tttacttctt
     9181 ttaaggagta taagagaaaa ggggatactt tcgtgtccat gcatgtaatt aactaattgt
     9241 tgagcttcag aagttatatc tctaattata tagttaacgg aattaggaag tgtctttaac
     9301 tctaatgaaa tttctatcca attactatct tctaatctgt atatgctcga agtataattt
     9361 gattcgtcag caagcatcgc tacatcccaa acactgatca taaaatcttt taaacgttca
     9421 atcatttcag caatattgct aaaatcagct aatttttctt tagaataaaa aaaaacattt
     9481 atatcagaat caataaattc tattttttta ttactatatc gtcatcatta tcttgaccat
     9541 ttatgtttat tgttccctga gtggggagta cttctttcaa attcaagtta aatttatatt
     9601 ccattacttc tcctccaata tataaaaatt acttaactgt atccaaattt aatatgtaaa
     9661 taaatcatta atttttagct aaattctatg agaagtttat ttttgttgtt tttgctaatt
     9721 aactaaaact agtacaaaaa atttaaaata gattattaaa cctattgctt attctattca
     9781 gtcatatata taagcgtcat cctttagtaa ctaacatccc acactacaat agtattataa
     9841 catatctatt caacttcaaa ttgttgaaat ttaagccatt tatatttact tttcctcaac
     9901 tttagaaatg attttactaa ccttatatcc gtaacacgcg taacaaacac attcattaat
     9961 aacaatcaac actaagctat attagctttt taaatgacta gggtaaataa aataaggatc
    10021 aaaaactttt aagtttctga ccctttcctt acttccgatt ggttaatagt gatcttttgc
    10081 agaataaata aatatcgttt cattttcaac tctatatatc agtctatgtt catctgtaat
    10141 tcttctggac cattttccag ataaatcatg ctttaatggc tcaggttttc ctaatccagc
    10201 aaagggggaa cgatcgatat cttttattaa cttgttaatc ttttttatat tgcttttgtt
    10261 tccttgctca tgccaataaa gataatcatc ccaagcatca tcagaccaag ccttaatcat
    10321 cagattcaac ctcgattaag tcatgtgttt taaatgcacc tttggagaat tgttcatctc
    10381 ctcgacgaat tttttccatg acgtaattat tagaaagtgt tctcaacgtt tcttgcatag
    10441 aatcataatc tctttttgat aatacaacaa ctgtatcttc tacatcttta cttgttacaa
    10501 taagtgtttc agcatcctca ttaacttgtt tcatataact acgtaaattt tggcggaaat
    10561 ttgaataagc tactgcttcc attcctttca ccccttattt atttctataa aacaattgta
    10621 cattatattg tacaattaag caaatgatta atattctaac ttcttataat taaaagtgct
    10681 atcactttta gtttttagga taaaaagtga cgtcactttt tgagtgctgg tacctcaaat
    10741 cctgcttttt cttgggcaat caataaatct aacgcaatac acataatcct ggattcactt
    10801 ttgccgtact tctgctttag ttgctgcaat tctttttgtc tcttttcatc caacgtaacg
    10861 ggtaaccgtt tatttcctat tgcaattggc attagtactc tctcctttca tcgaaataac
    10921 cctatgaaaa atatggctgc aatcatcttg aatagtagac tcacaagggc taatacaaag
    10981 cgccaaaaga tcaaacaaaa taccagtatt gccaaaaata ctacgaagtt taaatgcaca
    11041 gctgcagcat ggcgcataag tatttcgcca acaaatagga ctaacaatag aggaatgatt
    11101 ttattcatat ggatctcctt ctttctctta ggttatcggg tgttgcccgc ttatttcgca
    11161 ccacctaagc ggcgggggcg gttggagcga ttggtgcgaa ataagaacca ttcccttagt
    11221 tactaggttt tttgtcctta tttcacacat tctcactttt cggtataaat gattattgcc
    11281 tttttttcct ttcaaatcgt tgatatggca ttcgtttacg gtcaagttca ttttggattt
    11341 cttctgtatc gtcgtaagta taggtgtcta aaaaatcagt taaagtcgtg taccagtcgt
    11401 cgcctgggtt atctacttct tctacatatt ccctcaaaaa tgcttcgggt acagcgagtt
    11461 cataatccat tcccattaac acgatagatt ccgttccaca cgtcaaaaat ctagtaaata
    11521 caaggtaata atcgtctatc gtcgcatctt tgctgtttag ctcttccatt tcttcttcca
    11581 ttaattccat gctctcaaaa attgaataat attctgattc tgagtaatag tgtttcctgc
    11641 aaatcgtgta gctgacaaag ttttcgacca gctcactcct ttctaggtaa acattcatga
    11701 tgtatttttc tgtttctagt cgtagaagct ccgttccttt ttttaccgtt tcaggacgac
    11761 gtttatacac gtctaaacga ttatggctga ctgtgacctt cgtttgactc gtttcacttt
    11821 ccaaatacaa ttgttct
//
LOCUS       DAYYEF010000075        11748 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000075 DAYYEF010000000
VERSION     DAYYEF010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.078"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            413..619
                     /locus_tag="ACHA1B_002477"
     CDS             413..619
                     /locus_tag="ACHA1B_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HFM8703207.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(821..1822)
                     /locus_tag="ACHA1B_002478"
     CDS             complement(821..1822)
                     /locus_tag="ACHA1B_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM8703208.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1827..3740)
                     /locus_tag="ACHA1B_002479"
     CDS             complement(1827..3740)
                     /locus_tag="ACHA1B_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HFM8703209.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(3908..4414)
                     /locus_tag="ACHA1B_002480"
     CDS             complement(3908..4414)
                     /locus_tag="ACHA1B_002480"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase family protein"
                     /protein_id="HFM8703210.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4574..5014
                     /locus_tag="ACHA1B_002481"
     CDS             4574..5014
                     /locus_tag="ACHA1B_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFM8703211.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(5040..6155)
                     /locus_tag="ACHA1B_002482"
     CDS             complement(5040..6155)
                     /locus_tag="ACHA1B_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703212.1"
                     /translation="MKNYHLSCSLKKGNPIEGEEYRIRYFFHLMYWQSFDENHSDILS
                     SIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSITYVPEEMNKFVHPL
                     ITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYLEEDLLDTPDKVQES
                     WGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGTKKKVDAFGKSAEDR
                     DFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCMLVRDIFIKHEQPVIF
                     YIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYPIDKKAYDQTNTQIF
                     YWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6200..6556)
                     /locus_tag="ACHA1B_002483"
     CDS             complement(6200..6556)
                     /locus_tag="ACHA1B_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703213.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(6854..7828)
                     /gene="sgrA"
                     /locus_tag="ACHA1B_002484"
     CDS             complement(6854..7828)
                     /gene="sgrA"
                     /locus_tag="ACHA1B_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HFM8703214.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSEISTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(8024..8863)
                     /locus_tag="ACHA1B_002485"
     CDS             complement(8024..8863)
                     /locus_tag="ACHA1B_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="HFM8703215.1"
                     /translation="MIRIIRLIGSVLIVFVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            9048..9935
                     /locus_tag="ACHA1B_002486"
     CDS             9048..9935
                     /locus_tag="ACHA1B_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HFM8703216.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(10529..11223)
                     /locus_tag="ACHA1B_002487"
                     /pseudo
     CDS             complement(10529..11223)
                     /locus_tag="ACHA1B_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
     gene            complement(11207..11605)
                     /locus_tag="ACHA1B_002488"
     CDS             complement(11207..11605)
                     /locus_tag="ACHA1B_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HFM8703217.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3505 a         2323 c         1757 g         4163 t
ORIGIN      
        1 tatttttgtt tcttattttc taaaaaatta aaaaaaattt tggtgaatta agtatttcct
       61 tgataacact ggcttttggc ctcattttag gttatcattt gtaattttat ttcacagttg
      121 atatgattgt tatgtaaaat aaaaaagttt aggatacatc gaatttttgg ggaaattctt
      181 ttgggggtat cctaaatctt ttctattata ttcccatatt ttctattatt ggtctagacg
      241 tatgatggta aactttgtac ctatctgatt gctgaatcat taattgctta tcattagcca
      301 tctttgtttc aagttcgcta gatgatcatt ttattcacat cctaacaaac ttgtcacatt
      361 tatagattct taatctattt atcatacaat tataaaaaag gaggtgctgc ttatgaaagc
      421 tatccatatt tctttgcttt ttttcgctag tgcattgatt ttatttgcta ttcatctttg
      481 ttcccagcct tatatcaata acaacggaat attagtggaa ccagcattct tttgcttacc
      541 actcggcttt ttgtcccttc ttgcctccgc aggcttcgga tttgttgctt tttttaaacg
      601 atcaaaacaa caaatctgac ttataaaatt tacgtaaaag agatcgtgac aataatcgtg
      661 tgatattccc aaatttcgaa taaaaggtgc cccttgccat ctctaactcc tcagtcacaa
      721 gttacaatat tcataaacca tgaaaagctt gtttattgaa attgctcctt gtgacttgga
      781 gctaagtgac agattacaac ctcttttgca tcataagact ttactccttg aaaaacatta
      841 ctaacttttg atatgtttct tgcgcttgtt tattgctgaa atcaaactga tattcatggt
      901 tcaaaacagc atttttctcc gcataatcta cttttgtgac tttcaccccc gctttctcaa
      961 atacagaagt tacttcttcc atttgtttcg taaacgtatt tgtatttcca tccgttaaga
     1021 atgtgttttg cgtccaacga tccgcatgtc tgaccaaggc taaacttttg accttctctg
     1081 attgttcaaa gtccttatta tcaaagtaag cccatccaca tttttcataa agaaagctag
     1141 agattttatc acttacttga gtaagtgcag aaggatccaa cagaccagac aaagaaataa
     1201 acttcgtaat ctgcttgttc tccaaagtcg gatcaagatg atcagctttt ttaatttctt
     1261 cattttgaag tgctaacaaa tattctccac taatttgtgc acctgccgaa tttccaccaa
     1321 tcgaaatatt cgaccaatct gcttgatctt ttatctcttt tttagctgct tgaatggctt
     1381 cgttcaattg gataactggt gtaggatgtt ttgcttccgg tgatcgttca taatctatat
     1441 ttacgatgat ttgctgcgtg tctgaacata gatattccaa ataatcacga caatcatttt
     1501 tatcccctcc tacatatgcg cctccatgca tccagaaaag aatcggtaat tttttctttt
     1561 ccactttcgg tgtgtagata tccatattat tatttttgta ctttgaagga taggatattt
     1621 ctttttttat atcgatttgt tcgatttttt gctggaaatc atctggtcgg gcatatactt
     1681 gttctttttc acttgtgtca aattgttttc taacaagcaa gctaatcggc tttggtgtga
     1741 tttgattaat caaaaataca gtgactaaaa taactacgat gataactggt actgcaatca
     1801 ctattcgctt gaaccatttc attcatttac cctctctttc ttcgccaaat ccatgtgata
     1861 atcgtgctaa cagataaaaa tccacctgaa taaatgagaa gcgaatgttt cttttctcca
     1921 gttttcggca acattctttt ttttgcatct gtcttttttt gtactttcac tgtcatctga
     1981 atcggttgcg tatcatcact tgattgatcc tctcgaggtt cattctttcc cttattgtct
     2041 gcattctctg tcggatcttg cttttttggt ggagctactg ggattttttt gtaatagaaa
     2101 ataatagttg gtatcgtctc attaaaaatc ccttcagtcg gtccttcaac atttgctaat
     2161 tcgtatcctt cgaatgtctt ttgctctgtc atataatttt ctccataagc tccgtaaagc
     2221 tggatttcgt cctggtcttt gagtagactt ttattgtttt catccacata ctttacgttt
     2281 atctgatcat ggaacactac tttcaaaaag tccgttacat gtttcgtgta ggcagcatgg
     2341 tcaacttcct gtgcctttcc atgccctgct ccttctacta ataaaagatc tttataccct
     2401 cctgataact catataattt ttgcgcgtta gacacaggta ctacatcatc tgctgttcca
     2461 tggataatca atttaggcaa tgaatctgac attccaatcg taggtagagc agcttttgta
     2521 tccaaatgca tctcctgatc aaaatagtat tgtttcaaaa ggcccataaa taaatcttca
     2581 tgctcttgat ccccaatgat gtctaactga ttttttatgg catccggtag tgcgggggct
     2641 actgtctggc tgtacgtaaa acgtagttgt tcatcaattg atgcaaatcc gcaattttca
     2701 ataattcctt tgacattgac aggaatatct ttcgctaata cagacatcat cgtagctgct
     2761 cccatcgaac caccataaag taaaatcttt tgagatggcc gctctcgaac ttcttgattt
     2821 atccagtaaa ggacgtcatc tgactcatat tgtccatagg tcacataatc gcctccgcta
     2881 ttaccagtcg ctctggaatc aacaaataat aaattatacc cggccttata aaaatcattg
     2941 tattcttctg taacgatccc gttattccaa ttccctcgaa atccgccatg gatcatgact
     3001 gttttatctg aaccttgatc gacataatat gcatatacat ccatcatttt gccatcttgt
     3061 ttgtttagta cagtttgatg aagttgtttt gtatttggat agaagcctgt gttttctgta
     3121 ggcgttgtcc catcatctgt acctccaagc atcgacatca acacactgtt ttttgcaaaa
     3181 gcgatatcgt acaatagata agtagcaatc agatgtttga taatctcttt atctacacca
     3241 taatcattaa cagcaagctc agtgactaat aactctatta attttgactt gatgtcttct
     3301 gttggtccat taagtatttc tgtcatctgt ttaccgaagt aattcaaata ttctttacca
     3361 ttgaaatttt cacctttacc gatatcatca ttttctgtcc cattctcttt gtcacttact
     3421 ttagcagaag aggattcgtc gtttgacatt tttgtagctg ttgcttcttc tgtttgttgg
     3481 ttatctgtgg tagcggtcgt ttcttgatct gtgctagtaa cagatgtctc aaccgttgtt
     3541 tcagtatttg tttctgtttg tgaagtactc gatttcgttt catttccagc atcagtagtt
     3601 tctgtggttt ctacctcccg agattccgat tcggaagaaa tgctctctcc atatactgtc
     3661 cattgcggga cgcttgtact tacagcaaat aagatgacca acgctccctt taatacttgt
     3721 tttgttctca agctattcac tcctttttat gtttctagga gaattatatg taaacgcaaa
     3781 cattttttat acaaaaaata aatggtttat cccataaaaa tagaacagga ttattttctc
     3841 attttacgta ataaagcaga atggataaac cagtatccat tctgcttttt ttaaacgaag
     3901 aaacaactta ttgctccaaa aatgtcagaa atcgtttatc ccaaattttc tcgtaaaaag
     3961 cgattgtttc ctttgctttc ataaaaggat tatcataagt tgtcgttgct cctctacaca
     4021 tcataagctg gtatcctaat ccatgagcaa acttcacagt cgtatctata caatactctg
     4081 cttgtgcccc acataattcg atcgaatgac agtccaattc agttaataaa acactcaaat
     4141 tagtcttata aaatgaattc gcatgggttt ttctcacaaa ataactgtgc tcaggaatag
     4201 ataattccga caatagctcc catggttttg tttgtggcac taattgagca tcttcgtgtt
     4261 gaacgaaaat aactggtttc ccaatcgttt cgtatgtttt gattctttta ttcactaatg
     4321 ctgtcactgt ttctaattcg tgtatcggcg aagaatcaaa acatacccct ttttgtaaat
     4381 cgatcactac tattgcgtcg gctgtgtttg acatacttgt gccttctttc ttttttcttg
     4441 atttaatagt atttcttatc tagctagttc cattatacgt gacaacattt tcttatttta
     4501 cacctctaaa tggcactttt cgactatttc ttcatgttat tatttcataa atacttagct
     4561 attggaggaa tgtatgatga ttaaattgta tacaggttct ggctgctcgt cttcaagacg
     4621 cgcaaaacgt tggcttatcg tccatgatat accgtttatc gaacagaact taattcgtca
     4681 accactaacc aaaaatgaat ttatccactt actaaaattg acaaacaacg gcgtgaccga
     4741 aatgctctct actcattcta ttagttataa aaatcttgtt cacagaatag atgaactcag
     4801 tttgagtgaa ctatatattg agattcgtac atccccttct ttattgaaaa aaccgattat
     4861 ctacgaccaa tctgcaaaac ttttgactgg atttagcgaa gataaaatca ggatgttcct
     4921 ttctaaaact aaaagaaagc aagagctcaa cgaactcttg ctttctggtc atcttgtcga
     4981 ttttaaagaa aataatcttt ttgcaatgtc ttaattttgg cataaacaat ctgcttttct
     5041 taattaacga aatccaattt ttccaatatg gatctatttt tctcattcct gatttttatg
     5101 atttcagctt tcagacgcgc ccaatcattt tttgtaggtt gtccattcca gtaaaatatc
     5161 tgtgtattcg tttgatcata tgcctttttg tcgataggat aatcgctaat gacaatatca
     5221 ggtaactgat cagcggatgc actatatttt attgggcgtt cagtcataga taatatcctt
     5281 ttctttgccc ataattcctg tgttttacca tactttgatt gaatatagaa tatgacaggt
     5341 tgttcgtgtt ttataaaaat atccctgact aacatacagt attgaaaaat caaccgtctg
     5401 ttcttttcat aataagtatt aagctctgga attctgcgag ctaccccact aaaaaactgt
     5461 tgcatgattg gatacatcac tggaaatata tgctgaaaat ctctgtcttc tgctgatttt
     5521 ccaaaagcat ccaccttctt ttttgtccca aaaacccttg aatacaaatg gatcattgcc
     5581 aaattgacat atagataatt tttttctgaa gttgtaaaac aaatcttgaa gtttttttca
     5641 aaattttcta caatagacga ttcaatccag ccccaacttt cttgtacttt atctggagta
     5701 tccaacaaat cttcttccaa ataggtgttc attacaccaa acataaaata aaggtaagct
     5761 tgctctgttg gagtgatgtg attcatcgac cagaagtttg cttcaaaaaa aggctctagt
     5821 atgtaatgcg taaactcttc ttttgttatc aatggatgca caaatttgtt catctcttct
     5881 gggacatacg taatcgagtg gccttgtttc attcgttgca acgaaattct tagtaggctg
     5941 atccatttct ttctatctat actacgcgta tatggcgcat gtttcgcaaa tttttctaat
     6001 agttgacgtt tattttttat acttgataat atatcagaat gattttcgtc gaatgactgc
     6061 caatacatca agtgaaaaaa gtatcggata cggtattctt ctccttctat cggattacct
     6121 tttttcaagc tgcaagataa atgatagttt ttcaaaatag tattaagttc tcttaatttt
     6181 ctttgaatcg tacgcaaact tatataattt tttgactaag attttctaag gattgataag
     6241 tacctttgta aagtgaatcc agtaaaatat aaccaatcgt tccctctaaa agtatagaat
     6301 aaactttact cagtaaaaac tgagaagaaa actcgacttt tatcatcttg ttttctgaaa
     6361 gaaaagataa tttatattct ggataccttt cgcaaaacga ttctgcttgt tgaatcaccg
     6421 aattcatctt agccagggtg tagtttagat ctaaagcgat atccttcacc acatataatt
     6481 tctcgtctct ttcataacaa tagttcaaaa attgatatac ttgcctttca ttgatatcaa
     6541 taaattcttc aaacaaagta catactcctt tttatctatt atttagactt attccgacag
     6601 ctacatgaat aacgtacaaa tagattcgtt actgattttt cagagatact accatgcgca
     6661 gtgtgcattg tcaattattc ttgctcttat tttccatttg tgttcctgtt atttcctgtt
     6721 tctcaaatat gttagtaaac aaaaatagat ctggcaaagc tacaacttcg ccaggcaata
     6781 cagcactctc gaatgaaata ttcactcaaa aatctatcgt tttattcaat tttagatctg
     6841 ttgcttttat tctttatttc actcgatgga agagagaacg aaaatagctt gctcctacaa
     6901 tcaaaatgag taacacaccc atccatgtaa ttagcttgtt caaggttcta ctaccagttt
     6961 ctggtaaatc gctttttcta ttatctgttt ctttcgcttt ttcttgatga tcaattccac
     7021 gagaaacaaa atcaggctgt tttagcacac tttttaggtt gctccctgca tttctctttt
     7081 gttccttagt tggtatgata ggtaccaaat caagttcatt atttactttt cctgtgctgc
     7141 tttcgctgct cgtgcttcct gtgctactct cactactcat gcttcctgtg ctactttcac
     7201 tactcgtact ctccgtactg ctttcgctgc tcgtgcttcc tgtgctactt tcactactcg
     7261 tactctccgt actgctttcg ctgctcgtgt tttctgtgct aatttcactg ctcgtactct
     7321 ctgtactgct ttcaccgctc gtgttttctg tactgctttc actacttgtg ctatccgtac
     7381 tgcttggcgg tccaacaact gtccaactgc ttggtttcaa attctccgtg atcgtcatct
     7441 gtccatcata aaaaacaatc aaatcaactt tatctttact cttgatctca tcaatcgata
     7501 gttctgcaga aatcattatt gtatactcaa taccagcggt ccattgtacg tcttttaaat
     7561 aaacttcccc aataactttt tctgaacttc cattaccatc ccaaccatat gttagaacag
     7621 catgtacatc actagcattc acgcttttgt ttggtttgac tggaatagta atgacttgtt
     7681 gtgtcatgtc ataaacaatc cgatcagttt tcacagtaaa tgaaagattc tcatttgccc
     7741 gttcatttgc agaagtactg attccaatca ttgctgcaat tatactcagc ccaagaataa
     7801 caaataatac ggtcgctgtt ttcttcattt ctatcactct ccatataatt accttctatt
     7861 tgataaagga attatataaa atgaaaatga tgagaacacg acagtcagtt gtgaaaatct
     7921 aacaaaagat gtcgtgtatt cgcttgaatt tgtttacttt ttcgtttaat caatgacaga
     7981 cttaaaaaag caagaccgat atcagccttg ctttcttcat cttttattga taaacagcag
     8041 tgtatttctt catccgcttt gttttatatg catagagtaa caaaccaaca atcaagacta
     8101 acaagaataa tgtagttgat atagatgctt cagccccaaa gtttccccca gtaattattg
     8161 tattttgcga ttggatcaga gtggagaaaa aaccttgttc ttgcgttccg ctgactggta
     8221 tacccaaaat agctccttgt gtccaattcc aagtaatatg agcaccaata gccgtaaata
     8281 aacttcctgt actgtagata agtgcgctga aaaagcaacc tgctaaaaag atattgaaaa
     8341 ctgccagaaa tgtcatgtta ggattcaatc cgtgcaaaag agcaaataat gcagcagatc
     8401 caatcattgc tattaacgga ccaaatctaa gcatctgatg ctgaaaaaag ccacggaata
     8461 aaagctcttc tgatgccccc actgcaataa ataaaataaa actcgttatc agcggcacaa
     8521 tgtttgcgtt tcctgaatct aaccgatacg cccccgtcaa atataatgga ctagtaataa
     8581 gcagaaacac tccaattcca acaacgagac ctcccgctaa atacccccag tcttttcctc
     8641 gaacagaaac accataatct tctattcttt ttccttcgac cttactagca agaaataaag
     8701 ctagtaaaaa aacagctaaa tgtccgaccg taccggcaat tgctccaatc cattcactat
     8761 ttccaataaa catatccgca agtgcattat tgacaagaat tcctaaaaca aaaccaacaa
     8821 agactattaa aacagatcca atcaaccgaa taatcctgat catctttcat ccctccttta
     8881 tattaagttt aacaaccctt ttctttcttg tctcgtgaaa actatgtaaa tgttctccat
     8941 catagagaga atagattttt acgaactaag aatatctaca gcaaccttac gaaaatgaaa
     9001 gactgtctcc ctaattcttc tgttagactg tttttaataa ggaaaggatg ggaaattttt
     9061 tgaaaaaaca actactaatt atgtgccttt cagcatgtgc aattttacta ttctcaggtt
     9121 gtagcaagtc caatgaaacg attgcaacgt ttaaaggtgg aacacttaca gttcaggatt
     9181 tttatgataa cccaaaagtt aaatcaaata atcaaacact attaaaaaaa atgattgtct
     9241 tcaaagcatt tgatgatgta tacggaaaag agatttcttc aaaggaagta acaaaagaat
     9301 ataatgaaca aatcaaaaaa ctcggtccaa actacaagga acaattaaaa gcagttggcc
     9361 aaacagaaga gacatataag aaactcttta aacagatgct ggctttccaa tacggtttga
     9421 aagccaatgt aaaattaaca gataaagatc tagacactgc ttggaaagaa ttctatccag
     9481 aagttagtac acagatcatt ctattttcga ctaaagaaga agcagataaa gcaaaaaaag
     9541 aagcaaatga aggagaaaat ttctccaagc ttgttcaagc ttatggaaaa aataaaacat
     9601 taaaggaaac tgatggaaaa atgaattttg attcaaccaa tccagagatt cctactgaag
     9661 taaaaaaagc agcatttaaa ctaaaaaacg gggaagtttc tgatatcatt cctgtaacag
     9721 atccaacgac ttatcagcaa agctattatc tagtaaaaat ggtaaaaaaa caggataaag
     9781 gttctaataa agacaaatac aaatctgagc tagaaaaaat tgctaccgaa gcaaaaactc
     9841 ttgatacgga attcatggat aaaacaatcc gtaaagtgat gaaaaaagac aatgtaacta
     9901 ttaaagatcc ttatgtaaaa aatatattca aataaacaaa tttgacccaa ttggggatgt
     9961 ggcaaaattt gagaagtgat ttttggaaat tccttcttat ttttgaggca aaccactttt
    10021 gccacaactt catcggggcc tttttttatt tgtaccaaaa caaatcactg gatttgttac
    10081 aatcatgagg atataattta aaaaagtttt ttatttctat cacatgaatc aatgcgccat
    10141 taagtagatt ctttcatgct tccctatttt ttcacttgcc gtatcgcttc aaaaacaact
    10201 atcataaact caaactcgac tgaaaagtta ttttaaaaaa gactaaaaat atcccttctg
    10261 gacttgttct tcttattctg ttatactaga gaaacacgaa agatattttt atgcgacact
    10321 tttcatttgt ttttatgaaa tttattcaaa actggcgtaa cttcagagtt acaaggatgt
    10381 attagaggtt agggaataca tcgtttaaat gagaaataag taatagttag taatagtcac
    10441 ccaaacttta aattaatgaa tattgaatcg tcagatagcc tcctcgagtt ttcgagaagg
    10501 ctatcgttta ttttatggag aaattgattc agaagtaatc agcgaccttt tttagttcac
    10561 caatcgtttc tgcttggaaa gtttgcaccc aatcttcttg gaagcccctc actgctttat
    10621 caatcgaggg catctctaat acttgatcta gtagctcttt acctaacgtt atcgctgagc
    10681 tccagatcga atggctgtag tgacttgttc acaatttttg aaactagctg ctaatatttt
    10741 tgttggtctt tgcgtacgtt cgatctcagt ccgcaacgaa tcaatcactt tcatagcatc
    10801 aatgccttga ttttgcatcc tgttataata aggtgcaata taatctgctc cattattaat
    10861 agctaaatac ccttgtaatt ctgtgtaaat agctgtaccg gtaatcaaat aaccttcttt
    10921 tttcaacttt ttgatcgctt gaaggcctgc ttgattcacc ggcaccttga taaacgtatc
    10981 ttttcccagt tcttctatga taactcgagc atcctctatc atttcttctt ccgttcttcc
    11041 tattgtctga atatggatag gaatctgtcc gattattttt ttgatttctt tcatatgcga
    11101 gaagaagttt gacgctcctt cttttttcag aattgtagga tttgttgtta cgcctgttaa
    11161 attcaaaaac tgttgacaag aataaatact ttttgtattt gctgtatcaa gcatgatttc
    11221 catatagctt tcccccattc tgatcctctt gatcgatttt aatgattgtc ccctttctta
    11281 aatgcggcat ttccttatct tctacataca ttgttcctgg aagttccggc tcatgagatc
    11341 catcaaattt tatcgtgata tgtcctaatt cattcaaatt agtttggaca acatctccta
    11401 ctgctgtgat tacatacatt tgtttatcaa aacagagctt catatcacaa gttatttctt
    11461 ttcttacctg attcaattca atcttataac aataatctgt taatgtttcc ggtgcttcat
    11521 ctccaaataa aatcattatt ttttctttcc tgaatacttc tgcttctata ccaacatctg
    11581 ttacaaccgt ttcaaagatc gtcatctctg ttcctcctcg taaaatatca tttgtctaat
    11641 agtttttatt caaaatgttt ctagattata aaatttattg aataacacat tcctaacgga
    11701 atttgtttcg atattgtgtg atttctcaga gtacaatgga tgtatgga
//
LOCUS       DAYYEF010000076        11277 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000076 DAYYEF010000000
VERSION     DAYYEF010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11277
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.079"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            136..309
                     /locus_tag="ACHA1B_002489"
     CDS             136..309
                     /locus_tag="ACHA1B_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703218.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            949..1422
                     /locus_tag="ACHA1B_002490"
     CDS             949..1422
                     /locus_tag="ACHA1B_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HFM8703219.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="ACHA1B_002491"
     CDS             1431..1658
                     /locus_tag="ACHA1B_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703220.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="ACHA1B_002492"
     CDS             2294..2665
                     /locus_tag="ACHA1B_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703221.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="ACHA1B_002493"
     CDS             complement(2921..3163)
                     /locus_tag="ACHA1B_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFM8703222.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="ACHA1B_002494"
     CDS             complement(3195..4097)
                     /locus_tag="ACHA1B_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFM8703223.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="ACHA1B_002495"
     CDS             complement(4110..4298)
                     /locus_tag="ACHA1B_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFM8703224.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="ACHA1B_002496"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="ACHA1B_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFM8703225.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="ACHA1B_002497"
     CDS             complement(4913..5806)
                     /locus_tag="ACHA1B_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFM8703226.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6807)
                     /locus_tag="ACHA1B_002498"
     CDS             complement(5884..6807)
                     /locus_tag="ACHA1B_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046873 - metal ion transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0030001 - metal ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HFM8703227.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="ACHA1B_002499"
     CDS             complement(6856..7206)
                     /locus_tag="ACHA1B_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HFM8703228.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="ACHA1B_002500"
     CDS             complement(7239..8141)
                     /locus_tag="ACHA1B_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFM8703229.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="ACHA1B_002501"
     CDS             complement(8134..8991)
                     /locus_tag="ACHA1B_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HFM8703230.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9325..10134
                     /locus_tag="ACHA1B_002502"
     CDS             9325..10134
                     /locus_tag="ACHA1B_002502"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM8703231.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10174..10671
                     /locus_tag="ACHA1B_002503"
     CDS             10174..10671
                     /locus_tag="ACHA1B_002503"
                     /EC_number="3.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family cysteine hydrolase"
                     /protein_id="HFM8703232.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11056..11129)
                     /locus_tag="ACHA1B_002504"
     tRNA            complement(11056..11129)
                     /locus_tag="ACHA1B_002504"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11093..11095),aa:Ile,seq:cat)
BASE COUNT         3304 a         2104 c         1884 g         3985 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca tctttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtg gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac
     9181 tactatatat agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag
     9241 caagttagtt tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat
     9301 gtaaaaagaa agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg
     9361 cttgatcgaa atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa
     9421 aatggcggaa tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt
     9481 tccgaattag gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg
     9541 aaggatggaa aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga
     9601 aaagccttct tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa
     9661 gatgatcagc tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat
     9721 ttcaatttac agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt
     9781 agctatctta aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga
     9841 gatctgcaag cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg
     9901 cctacaggta tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa
     9961 tcgagtgaca tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc
    10021 gggttgagta ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta
    10081 acactgacga atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa
    10141 taaaatgacg atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat
    10201 catattcttg atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt
    10261 attgctcaaa gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat
    10321 ataccagttg aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt
    10381 ctttctccac aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa
    10441 actttagctg aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa
    10501 gtagtcggga ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct
    10561 tttcctgaag cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa
    10621 tccgctttag agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta
    10681 tcttcattta cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac
    10741 gtgctttttc tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca
    10801 cgacctcttt cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc
    10861 aaaatatgag gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt
    10921 cacaacctct tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa
    10981 gtaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggcagctt
    11041 tttcacaacc tcttatgtac cttgtaggac tcgaacctac gaccggacgg ttatgagccg
    11101 tctgctctaa ccaactgagc taaaggtaca tcataaataa aatttatttt tgttactttt
    11161 caactatagc acgaatgaca aactctcaca agtttcaaaa tataagtaaa ataatattgt
    11221 tattcttatt tcttttactt gtgtcataac tattttgtta ctttaatttt tatttgc
//
LOCUS       DAYYEF010000077        11255 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000077 DAYYEF010000000
VERSION     DAYYEF010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.080"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="ACHA1B_002505"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="ACHA1B_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HFM8703233.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="ACHA1B_002506"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="ACHA1B_002506"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA];
                     GO_process: GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HFM8703234.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="ACHA1B_002507"
     CDS             complement(2169..2906)
                     /locus_tag="ACHA1B_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HFM8703235.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="ACHA1B_002508"
     CDS             complement(2997..3524)
                     /locus_tag="ACHA1B_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703236.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="ACHA1B_002509"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="ACHA1B_002509"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009368 - endopeptidase Clp complex
                     [Evidence IEA];
                     GO_function: GO:0004176 - ATP-dependent peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HFM8703237.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="ACHA1B_002510"
     CDS             complement(4401..4886)
                     /locus_tag="ACHA1B_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HFM8703238.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="ACHA1B_002511"
     CDS             complement(5039..5236)
                     /locus_tag="ACHA1B_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703239.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="ACHA1B_002512"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="ACHA1B_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HFM8703240.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="ACHA1B_002513"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="ACHA1B_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HFM8703241.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="ACHA1B_002514"
     CDS             9211..9423
                     /locus_tag="ACHA1B_002514"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA];
                     GO_process: GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit epsilon"
                     /protein_id="HFM8703242.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="ACHA1B_002515"
     CDS             9425..11104
                     /locus_tag="ACHA1B_002515"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0004540 - RNA nuclease activity [Evidence
                     IEA];
                     GO_function: GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HFM8703243.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3266 a         2429 c         1971 g         3589 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaata
//
LOCUS       DAYYEF010000078        11096 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000078 DAYYEF010000000
VERSION     DAYYEF010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.081"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            33..656
                     /locus_tag="ACHA1B_002516"
     CDS             33..656
                     /locus_tag="ACHA1B_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703244.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1106..2155
                     /gene="trpX"
                     /locus_tag="ACHA1B_002517"
     CDS             1106..2155
                     /gene="trpX"
                     /locus_tag="ACHA1B_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan ABC transporter substrate-binding
                     protein"
                     /protein_id="HFM8703245.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2152..3033
                     /locus_tag="ACHA1B_002518"
     CDS             2152..3033
                     /locus_tag="ACHA1B_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8703246.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3036..3806
                     /locus_tag="ACHA1B_002519"
     CDS             3036..3806
                     /locus_tag="ACHA1B_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8703247.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4085..4939
                     /gene="aroE"
                     /locus_tag="ACHA1B_002520"
     CDS             4085..4939
                     /gene="aroE"
                     /locus_tag="ACHA1B_002520"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004764 - shikimate 3-dehydrogenase
                     (NADP+) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0019632 - shikimate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HFM8703248.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5117..6280
                     /locus_tag="ACHA1B_002521"
     CDS             5117..6280
                     /locus_tag="ACHA1B_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0070726 - cell wall assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HFM8703249.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6397..6807
                     /locus_tag="ACHA1B_002522"
     CDS             6397..6807
                     /locus_tag="ACHA1B_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HFM8703250.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6981..9209
                     /gene="topB"
                     /locus_tag="ACHA1B_002523"
     CDS             6981..9209
                     /gene="topB"
                     /locus_tag="ACHA1B_002523"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003917 - DNA topoisomerase type I (single
                     strand cut, ATP-independent) activity [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HFM8703251.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9380..9664
                     /locus_tag="ACHA1B_002524"
     CDS             9380..9664
                     /locus_tag="ACHA1B_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703252.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9824..10060
                     /locus_tag="ACHA1B_002525"
     CDS             9824..10060
                     /locus_tag="ACHA1B_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFM8703253.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10057..10455
                     /locus_tag="ACHA1B_002526"
     CDS             10057..10455
                     /locus_tag="ACHA1B_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFM8703254.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
BASE COUNT         3876 a         1834 c         2306 g         3080 t
ORIGIN      
        1 aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat
       61 cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt
      121 attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt
      181 tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa
      241 ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg
      301 cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt
      361 ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt
      421 atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt
      481 tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt
      541 ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag
      601 aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca
      661 ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg
      721 tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt
      781 cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt
      841 atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg
      901 agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga
      961 catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga
     1021 ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa
     1081 agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat
     1141 tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag
     1201 tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca
     1261 tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa
     1321 agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc
     1381 cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc
     1441 tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac
     1501 ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg
     1561 tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa
     1621 tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc
     1681 acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc
     1741 cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt
     1801 tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc
     1861 aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat
     1921 cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag
     1981 tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat
     2041 caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc
     2101 caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta
     2161 tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt catgacttat
     2221 cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc
     2281 tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt
     2341 gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt
     2401 attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga
     2461 acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg
     2521 ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct
     2581 gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac
     2641 gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact
     2701 ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca
     2761 gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa
     2821 gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc
     2881 atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag
     2941 ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg
     3001 aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa
     3061 atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta
     3121 accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa
     3181 gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta
     3241 aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt
     3301 tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg
     3361 cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag
     3421 attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag
     3481 cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag
     3541 ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag
     3601 cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca
     3661 cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga
     3721 aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc
     3781 agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact
     3841 tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa
     3901 catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt
     3961 ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc
     4021 gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa
     4081 taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag
     4141 tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt
     4201 agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga
     4261 tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga
     4321 ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg
     4381 tttgattggc tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat
     4441 ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac
     4501 tgttcaagct gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac
     4561 attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa
     4621 agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct
     4681 agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat
     4741 aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg
     4801 tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat
     4861 ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat
     4921 tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg
     4981 gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat
     5041 tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa
     5101 acgaggagga accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa
     5161 acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat
     5221 ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt
     5281 gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa
     5341 taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc
     5401 gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt
     5461 ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac
     5521 ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac
     5581 acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc
     5641 ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg
     5701 acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt
     5761 agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga
     5821 aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa
     5881 tctggatggt gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca
     5941 gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca
     6001 agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta
     6061 tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa
     6121 aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga
     6181 cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca
     6241 aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag
     6301 aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc
     6361 ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa
     6421 aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt
     6481 atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa
     6541 aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg
     6601 ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca
     6661 agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag
     6721 atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc
     6781 atcaactggc agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa
     6841 gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt
     6901 atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat
     6961 taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa
     7021 aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg
     7081 atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg
     7141 ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt
     7201 tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa
     7261 aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg
     7321 aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt
     7381 tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc
     7441 aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt
     7501 ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg
     7561 atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc
     7621 aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga
     7681 caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag
     7741 agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc
     7801 ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt
     7861 tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc
     7921 aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag
     7981 aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag
     8041 aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc
     8101 aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc
     8161 tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg
     8221 ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa
     8281 aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa
     8341 aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac
     8401 tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca
     8461 cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag
     8521 aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga
     8581 agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt
     8641 gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag
     8701 ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca
     8761 aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt
     8821 cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag
     8881 gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct
     8941 tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa
     9001 cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg
     9061 gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt
     9121 cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa
     9181 gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt
     9241 ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa
     9301 cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca
     9361 ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct
     9421 aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc
     9481 accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca
     9541 taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc
     9601 ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg
     9661 ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt
     9721 tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa
     9781 tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa
     9841 gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga
     9901 attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt
     9961 acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa
    10021 tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa
    10081 attatcaaaa tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta
    10141 aaagatgcaa atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa
    10201 gaactctatc ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa
    10261 catccttttc ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa
    10321 ttgaataatt gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt
    10381 accactagtt cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa
    10441 accgcaataa aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa
    10501 ggaatatgct gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga
    10561 aaatatggat taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg
    10621 aaatagtggt ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata
    10681 ttatacaaag tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc
    10741 gtcatttttc catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt
    10801 actttttttg tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata
    10861 tgaacgaatt agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca
    10921 cagataaaca ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca
    10981 tatgtacgga tacattttcg gaccgattaa ttttaaccat tctatttatt tgcttaccta
    11041 ttagatatca ataaaaaact gcttaacagc tatttcagct gttaagcagt tttagg
//
LOCUS       DAYYEF010000079        10237 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000079 DAYYEF010000000
VERSION     DAYYEF010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10237
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.082"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            162..392
                     /locus_tag="ACHA1B_002527"
     CDS             162..392
                     /locus_tag="ACHA1B_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 family protein"
                     /protein_id="HFM8703255.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            489..1790
                     /gene="murA"
                     /locus_tag="ACHA1B_002528"
     CDS             489..1790
                     /gene="murA"
                     /locus_tag="ACHA1B_002528"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008760 - UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase activity [Evidence IEA];
                     GO_process: GO:0019277 - UDP-N-acetylgalactosamine
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HFM8703256.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1803..1979
                     /locus_tag="ACHA1B_002529"
     CDS             1803..1979
                     /locus_tag="ACHA1B_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HFM8703257.1"
                     /translation="MSNQRYIILTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2114..2410
                     /gene="yidD"
                     /locus_tag="ACHA1B_002530"
     CDS             2114..2410
                     /gene="yidD"
                     /locus_tag="ACHA1B_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HFM8703258.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2594..3061
                     /locus_tag="ACHA1B_002531"
     CDS             2594..3061
                     /locus_tag="ACHA1B_002531"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8703259.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3146..4030
                     /locus_tag="ACHA1B_002532"
     CDS             3146..4030
                     /locus_tag="ACHA1B_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HFM8703260.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4144..4380
                     /locus_tag="ACHA1B_002533"
     CDS             4144..4380
                     /locus_tag="ACHA1B_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HFM8703261.1"
                     /translation="MMSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4468..4548
                     /locus_tag="ACHA1B_002534"
     tRNA            4468..4548
                     /locus_tag="ACHA1B_002534"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4502..4504,aa:Tyr,seq:gta)
     gene            4555..4626
                     /locus_tag="ACHA1B_002535"
     tRNA            4555..4626
                     /locus_tag="ACHA1B_002535"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4587..4589,aa:Gln,seq:ttg)
     gene            4751..4921
                     /locus_tag="ACHA1B_002536"
     CDS             4751..4921
                     /locus_tag="ACHA1B_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703262.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            5141..5848
                     /locus_tag="ACHA1B_002537"
     CDS             5141..5848
                     /locus_tag="ACHA1B_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM8703263.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5908..6552)
                     /locus_tag="ACHA1B_002538"
     CDS             complement(5908..6552)
                     /locus_tag="ACHA1B_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HFM8703264.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6679..6966
                     /locus_tag="ACHA1B_002539"
     CDS             6679..6966
                     /locus_tag="ACHA1B_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703265.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7074..7394
                     /locus_tag="ACHA1B_002540"
     CDS             7074..7394
                     /locus_tag="ACHA1B_002540"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM8703266.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7475..8788
                     /locus_tag="ACHA1B_002541"
     CDS             7475..8788
                     /locus_tag="ACHA1B_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HFM8703267.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8785..9504
                     /locus_tag="ACHA1B_002542"
     CDS             8785..9504
                     /locus_tag="ACHA1B_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HFM8703268.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9632..10183
                     /gene="raiA"
                     /locus_tag="ACHA1B_002543"
     CDS             9632..10183
                     /gene="raiA"
                     /locus_tag="ACHA1B_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005840 - ribosome [Evidence IEA];
                     GO_function: GO:0045182 - translation regulator activity
                     [Evidence IEA];
                     GO_process: GO:0009386 - translational attenuation
                     [Evidence IEA];
                     GO_process: GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HFM8703269.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT         3413 a         1693 c         2186 g         2945 t
ORIGIN      
        1 ttttgtctca gtcccttttt ttgcatattt ttagcattta tttcctaaaa aatgtaaggg
       61 gattcctata tttttaagta tacttgtttt tccttttata cattttatgg tattatcatt
      121 ttattagtta ttataaaaca atcgttagaa aggacgtcat tatgcaagta tacggaattg
      181 atgcggtgct tcgaatcgtg agtcatttgg cgtttatcta cttagccttc tggtctttac
      241 gttcgttacg cattgaaact tttttcagac caatgcataa tacgcaaatt agaatggcaa
      301 tcgtactttt ttcaattttt ttagggtaca ctgcaagtaa ttttttctta gaagttatcg
      361 ctttatgccg aaatcttttc gttagcctgt aaattttaaa aaaaggtact attttaaaag
      421 caaggatgtt ataatagaaa agattttgag taagtgtatg ctcattggaa ttttttggag
      481 ggaacaacat ggaagagatc atcgtaagag gtggcaatca attaaatgga acagtaagaa
      541 ttgaaggagc taaaaatgct gttttgccta ttttagctgc tagtttgtta gcagaagaag
      601 gtattacgac attagacaac gttccgattc tttctgatgt cttcactatg aatcaagtga
      661 ttcgtcactt aaacgtagat gtagattttg atgaacaaaa gaatcaagta acaatcgatg
      721 cttcaagaca attagaaatc gaagcgcctt atgagtatgt tagtcaaatg cgtgcttcaa
      781 tcgttgtgat gggtccgcta cttgccagaa atggacatgc aaaagtagct atgcctggtg
      841 gatgtgcgat tggtaaacga ccaatcgatt tgcatttaaa aggatttcaa gctttaggag
      901 caaaaattat tcaaaaaaac ggctatatcg aagcaattgc ggatgaattg atcggtaaca
      961 cgatttattt agatttccct agtgtaggtg ctactcaaaa tatcatgatg gctgccgtaa
     1021 aagcaaaagg aacaaccatc attgaaaacg tagctcgcga accagaaatc gttgatttag
     1081 caaacatttt gaataaaatg ggcgctcaag tctatggagc tggtactgaa acaatgcgta
     1141 ttgaaggcgt ggatcattta catgcagtca accactcaat cgtacaagat cgtatcgaag
     1201 caggtacctt tatggttgct gctgcaatga cacaaggcaa tgtgctgatt gcagatgcta
     1261 tctctgaaca taaccgccca ttgatttcta aattgatcga aatgggtgca gaaatcattg
     1321 aagaagaagg cggagtccgt gtcatcggac caaaacatat cttacctaca gatgtaaaaa
     1381 cgatgcctca tcctggtttc cctacagata tgcaagctca aatgacagct atccaattag
     1441 ttgcagaagg tacaagtgta gtgactgaaa cagtgtttga aaatcgtttc caacatttag
     1501 aagagatgcg ccgtatgaac gctcatgtca aaatcgacgg aaatgtagca atcatggatg
     1561 gaaaccatga attgcaaggt gcagaagtat atgcaacaga cttgcgggca gcagcagcat
     1621 tagttttagc tggcttgaaa gcaaatggaa tcacacgtgt gcgtaacttg aattatctag
     1681 accgtggata ttataatttc catatcaaac tacagcaatt aggtgcagac gttgaacgtg
     1741 tagacatgga tcaaacttct gctgaaaaaa cagcacaaac gattgcttaa ggaagtggct
     1801 gaatgagtaa ccaacgatat atcatattaa ctttgataaa gattttagtg gtgatcttat
     1861 tgcttatcct tctttttgtg gccggaacga tgatcggata tggtgtcatc ggtggcggca
     1921 atccatttaa agtattccag ccaagtttgt ggattcatat tcgagacttt tttcattgat
     1981 aaataagaat cacagtggtt ctagtcgata tgaagtgagc catgaagcag aacatgacaa
     2041 aagaaaacag aagggaacgt tgacgttagt cgcgatccct ttttttagta aaagaaaaga
     2101 aggaatctaa ttgatgaaga agatattgat ttatttagtt agaggatatc agcgctttat
     2161 ttcgcctgca tttccaccta gctgccgtta ttacccaacc tgttccaatt atatgataaa
     2221 agcaattcaa acccatggtg cactaaaagg gacggtaatg gggactgcac ggatcttacg
     2281 ctgtcatcct tttgtcaaag gcggtatcga ttatgtacca ttgacattcc aattaacgcg
     2341 aaataagaaa gataaaaaag aaccagatta taaaaaggtt gtgaaaaata cgagtagcac
     2401 tgagcgataa agaaacaatt tggaaaatag cttcttatat tttgcaaaat tgtgagttat
     2461 tgccgaagtg ttggattttg aacaccgtca aaaaaaggtt gtgaaaaata cgggtagcac
     2521 tgagcgataa agaaaaagag gaaaattatt gtcaaagtaa caactccgca actacttata
     2581 tgggggacaa aaaatgatcg aagaactaaa caagaaagat ttaccatggt ccttgttatt
     2641 agatgcagat cctgataaag aaaaagttca agtatatgtt tccagaggga gtggctggat
     2701 atggaaagaa aaagaaaaaa caataggtgt actgatctat gtggcaaggg aaaaagaata
     2761 cgaaatcgtc aatgtagcag tagccccaac gtatcaagga aaggggattg gcggaaaatt
     2821 acttgagaca gcttttcaga agctttcaca actcgcttcc agtcaaactc agatcatcat
     2881 acgaaccggc agtactagca gtgcggcgtt acatctctat caaaaaatgg gctatgtgga
     2941 gattggtcga gtcaaagact attttatcca tcattactct gagcccattt ttgaaaatgg
     3001 agatcaatta agggatcaag taattttagc aattcactta cctaaaaata gctttaacta
     3061 ataaactttc aattcgagaa aatgctttca aatgctaaat agatacatta caatagcttt
     3121 agcaaacaaa aaggagaata tttttatggg aatattagtt tttgattttg gtggatcggc
     3181 tgtcaaatat ggttgttggg atggcaaaga gattaaaggt aagggacaat ttgcaacgcc
     3241 tgaatcttgg gaagaaatga aagcgcaatt atttcaagtt tataaaaaaa tactcgtttc
     3301 ttttgaagtc gaaggaattg gaatcagctc tcctggagta gtgaataatg agaaacaggt
     3361 gattgaggga atcagtgcga ttccttatat tcatggattt aatattttcc gagatttgga
     3421 aactctgttt caactcccag taacgattga aaatgacgcc aactgtgccg gaatggctga
     3481 attttatgaa ggtgctgccc gtgattatca agatgttgct tttgttgtgg caggaactgg
     3541 gattggcggg gcgttgttca cgaaaggaca aatcaataaa ggggcacatc tttatggtgg
     3601 agaatttggg ttgatgttct taaatggcga taagacattc agtaaacttg gtacagcggt
     3661 acagatggct tggcgttatt gtgaacgcaa aggtctcgat aaaaattctt ataccggaaa
     3721 agatgtcttt gaattagcag aaactggaga tgcaatagca aaagaagaag ttgagagttt
     3781 ttatacgtat cttacaaagg gattattcag tattcaattt tcgtttgatc cagaagtgat
     3841 cgtattaggc ggcggtgttt ctgcaaaaga agggctcatt gatgagatca aaagccgaat
     3901 gaagaagctg acagaacaat tcgatctgca tgatttcgaa ccgcagattt tattatgtga
     3961 atacagaaac gatgctaatc ttgtaggtgc agcagcaaac tatctcgctg tacgtcaagg
     4021 ggagaattaa gagctttaga gaaggtgcag cttgcataaa agaagtgaat gaaatgaata
     4081 ggagattttt acctaaggaa tgttttattt gctgcagtat gataaaatat ctgagaggtg
     4141 aaaatgatgt caaaaaaaaa taaagatgtt gaagtgcgta tagaagaagt gaaaaaagat
     4201 atcaaaggta agaattatga agtcactcag ttatttatag ggaaaaaaat gattggtgag
     4261 atcttagcct atgggccaaa agaatatgaa attttctttg gtgaagaaga ttttggaaaa
     4321 gaaaaaagtc ttgaaaatgc gatagaaaca gtgattcgac actggaatct gcacgaataa
     4381 aaaaatatca aaaaaacttt caataaaggg ttgcaaaaat ctggaaaatt aggtattata
     4441 actaagtcag gttgatacaa acctttcgga ggagtagcga agtggctaaa cgcgacggac
     4501 tgtaaatccg ttccttaggg ttcagtggtt cgaatccact ctcctccatt tcattggggt
     4561 atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta
     4621 ccccagtata ccacaatcgt aagctctcgt tagttcgaga gctctttttt ttgctttgct
     4681 accttgttcc ttgaagattc tgctgattta agatagagtt aagttaacta caagaattgg
     4741 agggatccac atgaaatgga aagaaaaagt agacgaagca gctgaaaagt tatatgattt
     4801 ggtcaaatca gaaaaataca atattgaagt gaatattccg aaaaaaggcg gaaaagcggt
     4861 ccaggtaaaa tcaaaacgcc caacgaatca tacaaaaaaa tggatggcta aaaaccgcta
     4921 ataataacaa aagatccata agtcggcatt ttcatcgatt ttagggtctt ttgttatttt
     4981 ctaggttgaa catatctaaa aaattgtttc tgacaatagg agtaggaaga acgatgtgtg
     5041 tctaaatcct ctgttgatgg atagaaacct ttatcttttt cagttgtgaa tcaggtatat
     5101 accagttata atagaagaaa cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt
     5161 atatatacag attcatgacc aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg
     5221 agaccgtctt ccttcagaaa gagaattagc agtgaaattc aatgtcagcc gtatgacgtt
     5281 gagacaagca attcaaaact tggcagatga aggaatctta gaaagaaaga tcggttcggg
     5341 tacatatgtt gcgcgagaaa aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga
     5401 aattatggaa tcgcaaaatc gagtaccgtc tagtcggaca atctcttatt tcttgacttc
     5461 gccaagctca agtgaaatgg aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat
     5521 ggaacgtatt cgtttcgcag atgatgtccc tatttgtttt gaagttgcca gtgtgccaca
     5581 aaagctgatc gatggctaca gcaaagcaga gattactgaa tcgttgtatc gcacgctaga
     5641 agaaaaaggc gggaaaaaga tcggtccagc gaatcaaacg attactgctg tgttggcttc
     5701 tgagaaaatt gctgactatt tagaggtaaa acgaggagat gcagttcttc gtttgcgcca
     5761 gatttcttat tttgaagacg gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa
     5821 tcgttttgag ttttatttgg aaaaataaaa aacaggtgat ccctgattcc ttacttagaa
     5881 ataaaagaga atcagaatca cctgttttta tatatgatca gttaccagtt gctcgtgata
     5941 agaaacagga ccctcttcaa attggacttg tccgttcagc agctcaatga tggattcttt
     6001 aaagtggtca gcactttttt catctacagc acagatgacg ctaacttgat cagtatattg
     6061 gatttctttt ataaaaaaat gttggagttc aagataattc tgtaattttc ctagttgcgg
     6121 atacgtgatc atcacagaga tctcctgttg caaggtacct tctacgattc caatgtcaga
     6181 caatgcttga gagacagcat gagtgtatgc tcgtattaat ccgcctgtgc cgagtttcgt
     6241 tcctccaaaa tatcgagtga ctactgcagc tacattgatc agttgatttt ttttgaggac
     6301 ttccaacatc ggtacgccag ccgttccact tggttctcca tcatcgctgc ttcgctggat
     6361 ttcatttttt tctccaatga tgaaggcgct gcagttatgg ttcgctttcc aatgttcttt
     6421 ttttatttct tgaatgaaac tttttgcttg gtcctctgat tctattcgtc taagagaaca
     6481 gataaagcgt gattttttga tctcaatctc actttgtcca ttttctttta ttgtacgata
     6541 gcgctcgatc atcttgtcac ctcttttttt cattttcttt attcagtata aataaagttc
     6601 taggttgttt caacactgta acggttgcgc aatcgctgta gtatgcgata ataaagacaa
     6661 aggtaggtgg atctggggat gcaggaacga atgaaaaagt acgatgcaat tacgcattat
     6721 ttgaagaaca atggcggctc tcaagtaacg ttgaccttta cccaatttga cgaactgctg
     6781 tttcccagta acggacttcc caaaacagca agggaaagta cagattggtg ggcaaatgat
     6841 tataaacacc ctgaaaaagg tgcctatggc tggataaatg caggctatga agtagttgtc
     6901 atcaatttgg acaaagaata tgtcgtgttc aataaattag tgaaatctag ttggctattt
     6961 gattaaataa accgcgttta gaaaacgttg acaaatttct ttctttttat ataatagagt
     7021 aacagacgcg aagaaaacgt ttgcgtagtt tgttttaaaa aggagagaaa agtatggcta
     7081 aaaaaacaat catgcttgta tgttcggctg gtatgagcac aagtttacta gtaacaaaaa
     7141 tgcaaaaagc tgctgaagca aaaggaatcg actcggatat tttcgctgtg tccgcttctg
     7201 acgcagataa caatcttgca aataaagatg tagatgtact gttattagga cctcaagttc
     7261 gctttatgaa agctgatttt gaaaaacgtc tggaaccaaa aggcattcct ttagacgtca
     7321 tcaatatggc tgattatggt atgatgaatg gcgaaaaagt gttagatcaa gcaatcacgc
     7381 tcataggtga ataaatagaa cagtataact atcgaacaag cgatccaaaa aatagatcgc
     7441 ttgttttttc gtatattttt ttagggcgaa taatatgaat catttttggg gtagaaggct
     7501 tctgacgaga gatattaaag caatagactg tgaggaggta aatttaccaa attatgagaa
     7561 gatcgcagca gtggaacgtt tgggcaactg gattctttgt catcgctgtg gaatgaggac
     7621 gtccgtcatt gatggacagc ttgcagatta cggttatttt tgtacacatt gtctatattt
     7681 agggcgatgc gacactcaac aagatttata tttgtttgat cagcctgaag caaaacctcg
     7741 agaagtcgtc tttttttgga caggacagct tactgaaaaa caaacggaaa tcgcaaagag
     7801 aatactttgc cattcagaaa aaagacatca tcttatttgg gctgtaacag gtgcagggaa
     7861 aacagagatg ctttatccta ttttagtgga aactttaaaa gctggaggaa gagtagcgat
     7921 ttgtacaccg cgagtcgatg tttgtaatga attgttttta cgctatcgtt atgtttttcc
     7981 agaagaaaaa atcacgttgc tccatgggaa tacagcaacg gcttatacct ttacttcttt
     8041 tgttatctgt acgattcatc agctataccg tttttatcgg tcctttgatt taatagtgat
     8101 cgatgagatc gatgcgtttc cttataacgg ggatgcagga ttagctcatg ctgtgcaaac
     8161 agcgattaaa ccagacggac gattcatcta cttaagtgcc acacctgata aaaagttact
     8221 aaaggaaatc aagcagacgt ttgacatcca caaacttgct ttgcgctttc atcggcgttt
     8281 acttcctgaa cccgtcttgg ttttcatgaa taattggcga caaaaatgca agaacaagaa
     8341 gaagataaaa tctttggtgc ggatcattca tcaattaatt aaagaaaacc atatcctttt
     8401 attttgtcca agtatcacga tgatgcatcg tttgaaagcc acacttcaag aggctcttcc
     8461 gagatatgag atcacagatg tttcttcaag agacaatcag cgggcggaaa aagtccagaa
     8521 aatgcgagaa gcaaaatatg acatactgtt aaccacgatg atccttgaac gtggagtcac
     8581 atttgaaaga atatccgtta tcgttttagg agcggatcat ccggttttta ctaaatcttc
     8641 tttggtacaa atcgcaggaa gagccgatcg taaagggcct tatacgaaca gtcaagtata
     8701 ctttttctat gaagaaaaaa ctgcagctat tcgaaaagct tgtcaggaaa tcaaagaaat
     8761 gaatgaagaa gggaagaaga tgctgtgagg tgcagttgct gcagtaaaga tatcgtccaa
     8821 aatttaacat tcagcgagat tattggtgtt tcgaaataca gattacctca gacttgttca
     8881 gtttgtcgcg cacaatttca tttattggaa acaagaggct gttctggctg tcaaaaacca
     8941 atccatttca atctagagag tacgaaaaag aaagtaaagt ctattcccgt ttactgcagt
     9001 gactgtcaag aatggaagaa gaaatatccg acctatgatt ttcagcaccg tgcctttttt
     9061 gtgtacgatg aaaatatgaa ggcctggctc aatcaataca agtttatggg agatatccga
     9121 ctagcaggca cctttgcata taaatggacg cagataaaaa aagaataccc gacatacatc
     9181 tattgtccaa tacctttatc tgaaaaaagg cgaacagaaa gaggattcaa tcaagtaagc
     9241 gagatgttga aagcagcaag aattcctttt cagatgctac tcaaaagaga gaagcatctg
     9301 ctggctcaag caaaaaacac gcgaaaggaa agattggaga tgcctcaacc ttttgaactt
     9361 gcagtcacct tttctaagat acaaaataaa aaaatattga ttattgatga tgtctataca
     9421 acaggacaga ctcttttcca cgcagcagat tgtttgcagg tcgcacagcc gaaaatcatc
     9481 cgaaccattt ctttagcaag atgaattaga tgtggaaatt tgatagcgat ttaatttgca
     9541 aataacctag agttcgatat aatagaatta agaagaggga aagagtggtc cttctccttc
     9601 ttgattgtgg tagacgaaag gggtaatttt tatgtttaga tataatgtac gcggcgaaaa
     9661 tatcgaagta actgaagcga ttcgcgacta cgttgagaaa aaagtaggca aactagaacg
     9721 ctatttcagt gacgcacccg atgcaacggc gcatgtgaac ttaaaagttt atacagaaaa
     9781 aacagcaaaa gtggaagtaa cgatcccatt accttatctt gtattacgtg ccgaagaaac
     9841 ttctccagat ttatacgcaa gtatcgattt ggttgttgac aaattggaac gccaaatccg
     9901 caaattcaaa acaaaaatta atcgtaaatc ccgtgaaacg ggcatgaata ctgcagatgc
     9961 tactgcttta ttcaatgaag aggacgaaaa cgaaaatgat tctgaattag atatcgtacg
    10021 tacgaaacgc ctttcattga aaccaatgga tagtgaagaa gcagtcttac aaatgaacat
    10081 gctgggacat aacttcttta tttttgaaga tgcagaaaca aatggtacaa gtatcgttta
    10141 ccgccgtaaa gatggaaaat acggactgat tgaaacagac tgatcagcct tacttaaata
    10201 acaacgaaaa cttgcagcag ctactgacag ctgccgc
//
LOCUS       DAYYEF010000080         9665 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000080 DAYYEF010000000
VERSION     DAYYEF010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.084"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..632)
                     /locus_tag="ACHA1B_002544"
     CDS             complement(<1..632)
                     /locus_tag="ACHA1B_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HFM8703270.1"
                     /translation="MEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAGANKKLV
                     YNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLKILTTFL
                     YVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKFVYDDFS
                     DELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIG"
     gene            975..1391
                     /locus_tag="ACHA1B_002545"
     CDS             975..1391
                     /locus_tag="ACHA1B_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HFM8703271.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1388..1858
                     /locus_tag="ACHA1B_002546"
     CDS             1388..1858
                     /locus_tag="ACHA1B_002546"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HFM8703272.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            1872..2645
                     /locus_tag="ACHA1B_002547"
     CDS             1872..2645
                     /locus_tag="ACHA1B_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HFM8703273.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2659..3471
                     /locus_tag="ACHA1B_002548"
     CDS             2659..3471
                     /locus_tag="ACHA1B_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:1902495 - transmembrane transporter
                     complex [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA];
                     GO_process: GO:0008643 - carbohydrate transport [Evidence
                     IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HFM8703274.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3525..4490
                     /locus_tag="ACHA1B_002549"
     CDS             3525..4490
                     /locus_tag="ACHA1B_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFM8703275.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            4606..7329
                     /locus_tag="ACHA1B_002550"
     CDS             4606..7329
                     /locus_tag="ACHA1B_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFM8703276.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7342..7974
                     /locus_tag="ACHA1B_002551"
     CDS             7342..7974
                     /locus_tag="ACHA1B_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HFM8703277.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            8873..>9665
                     /locus_tag="ACHA1B_002552"
     CDS             8873..>9665
                     /locus_tag="ACHA1B_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703278.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLY"
BASE COUNT         3260 a         1477 c         1884 g         3044 t
ORIGIN      
        1 ccaatcatat ggaagccacc gattaggtat tttatgggtt tagtcggaaa tgtttcaaga
       61 gcaatttcca tcatatcgat aatgccatga tgactacagc cagtaaagac aatcagaccg
      121 tcttcttgct caattacgac caataattca tctgaaaaat catcataaac aaatttatca
      181 tccatctttt tgtataaatt cttggtggtc gagtttgctt tgcctagggg gatgatatgg
      241 aagctcggag caagttctgt tttcgttttt attgtatgta aattctcatg cattttaagg
      301 atttcatttt taggaatacc aacatacaga aacgtggtta aaatctttaa ataatggggt
      361 aaagttacac cttcagctgt ataaataggg gcgtttcctg attttaaata tcttaacccg
      421 ccggtgtggt cagaatgacc gtgtgaaata atcactgcct ccagatcatt caaagtttcc
      481 cccattttag tcgcattata gactaatttt ttattagcgc cagcatcgaa gagatatttc
      541 ttccctgagt agttaattaa gagagataac ccatgtccac ttttaaagtt caaatttatt
      601 cttgagtttt caaataaaac cttgatttcc actataacat ctcctttcac atgaacgtgt
      661 attcatatat tgtagcacat taagttctat tttttgttgt aattaccgaa aaaaatatta
      721 atggacgctt tttacgcttt atttcgtatg tggaagaaaa tttcttagga tgtggcgggg
      781 gattggggca aagctaaatt ccaattacag tgatcattta attagacacc tttaaatacc
      841 cacactttca tcaacactat aatttaggga aagaaaagtg ttggcatgat atagaaaaac
      901 ctttaattaa cagcgtttcc taaaattggc acgcatcttg cttatagaaa agcgtaagga
      961 taggaggaat gaaaatggca actataattc ttgccagcca tggggaattt gctcaaggat
     1021 taaagcaaac agctacaatg attattggag atagtgtacc aattcatgcc ttgtcagcat
     1081 ttagagatga agatgaatct attttggtac aaataaaaaa acttttagcc acaatagata
     1141 tagaagaaac ctacatttta actgatattc taggtggtag tgtgaataat gatatgctca
     1201 ctattattaa agagtatgag ggattgcaat taattactgg aatgaactta cctttagtta
     1261 tttctattgc aacctataat ggaaaaattg gggaaagtga gctagaaaag cttattaaag
     1321 agagtcaaca atcagtgatt gattgtagaa aattattagt agaacaactt actggaggag
     1381 atgacctatg attaagttag tacgtattga ccatcgtttg ttgcacggac aggtagtatt
     1441 ttcttggagt aaatcattaa atatcaatcg tattattatt gccaataaag aggcagcgaa
     1501 tgatgaattc aaaaaaatgt ctttgaattt atctaaaccg actggcatta aattaacaat
     1561 tttttcagtt gaacagttac tagaaaaaat gcctaaaatc gaaacactta acgaaaatat
     1621 catgcttatt tttggtaata caaaagaaat tcgtcaattt tgtgaagcct atcctaaagt
     1681 acaagaaatc aactatggag ggataatcaa aaaagaaggt tccaagcaat ttagtaatgc
     1741 cattttcttg aatgaatctg agcaagaaga tgccaaaaaa ttaaaagctc ttggcattaa
     1801 acaatttatt caacaggtac caacttctaa aaaagaagat ttgaatacaa tgttataaag
     1861 gaggaatgaa aatgctcgtt cagtcaattg gtttagggtt aatcggtgtt ttttgtattt
     1921 tagactcaag gcttttagga agaatgaatt ttgaacgacc gttgattgtc agtacgcttg
     1981 ttggtttggt acttggagac atggaaaaag gattaattgt tggagcctct ttggaattga
     2041 tgtccttagg attagtaaat atcggagctg ctgcaccacc tgatatgaat atggcatcaa
     2101 ttattgctac agcctttgcc attttatcaa atgcgaatgc agaagcagca ttaacgattg
     2161 ccattccaat ttcagtgtta ggtcaaatac taggtatctt aatgcggacg attttgtcaa
     2221 atttgactca cgttgcggat cgctttatcg aacaagggaa atttagccaa gcaaggagaa
     2281 ttcatatact ttatggctcg ggattatatg ctctcatgta ttttattcct atttttctag
     2341 caatttattt tggaacgaat cttgtttctc agattgttga tgcgattcct gagtggctaa
     2401 caaatggctt aacggttgca agtaaaattt taccagcata tgggtttgcg ttgttattac
     2461 aaacgatgtt aacgaaaaaa atggtgccat ttttattact tggattttta attactgctt
     2521 attctggatt gggaatcatt ggtattgcag ccttcgcatg tattgttgcg tttgtcatgg
     2581 ttcaagttca aggtaaaaac tcaaatggta accaaaatga gccagatcca ttagatgact
     2641 tataaggagg tagattaagt gaaagagaaa gatcaaaatg catggaaata tcggcagttc
     2701 ttatggcgtt catgggcaat tcaagcctca tggaactatg aacgacaaat gaacatgggt
     2761 tttatgtacg gaattgcacc aattctagat aacatttaca agaatccaga agatgaagca
     2821 atgaagaaag aagcttacga gcggcatatg atgtactaca actgtacccc tcaaacaagt
     2881 gcatttgtgt tagggttaac tgcttctatg gaggagcaat actacgaaga ccaagaaaac
     2941 tttaatccgg aatcaatcag tgcagtgaag acttctctga tgggaccgct atctggtgtt
     3001 ggtgattctt tctttcaagg aacgattcgg gtattagcct ttggactagg aattaattta
     3061 gcccaacaag gtagtatttt aggtccaatt ctagcaatgt taatttcctt tgtaccttcc
     3121 tttttagtta cttactatgg tgggaaaatt ggctataaca tggggaataa atacttgtct
     3181 aaactgtatc aagaaggttt gatggataaa gtaatgtatg tttgctccat tgtggggttg
     3241 atggtcattg gttcgatgat tgccagcatg atcgggatta caacaccaat tcaaatgggt
     3301 aaagcttttg tcttacaaga tgtattagat agtattatgc cacaattttt accattagga
     3361 ttaaccttct tcatgtactg gttattgcag aaaaaggtca aaacaggatg gatgttggca
     3421 atctgtttag tcggaggaat tatttttagt ttgttaggta tcttacaata agggaataac
     3481 caataaattt ggttgaataa tataaataag gaggaattca attgatgaat tcaaaagaaa
     3541 ttgttaaaga aatcgtagcg aaaaaagagg taaaatcaat cgtatttgtt ggctgtggcg
     3601 cttcaaaagc ggacctttat cctgcaaagt attttctaga ccaaaatgcg aagcagttac
     3661 ggattagtca ttacacagcc agcgaattta actatgcaac accagcatct gtagatgagt
     3721 caactgtcgt tatttcagct tctttaggag gtacgactcc agaaacagtt gaagctaacg
     3781 cagtagctaa agaaaaaggt gctacagtta ttagtctaac acgaagcatt gactcaccgt
     3841 taacaaaaga tgcagattat gtaatttatc atcgatttgc agagaactat gctgctaaat
     3901 tagaaaaaac aggctactgt ttagaattgg cagtagaact tttacatcaa gtagaaggtt
     3961 atgaccatta tgaagcaatg caagaaggat ttgctactat ctatgatctt gcccaaaaaa
     4021 gtgcagaatc agctcgtaaa gatgcgaaga aatttgctga acgctttaaa gatgaaaaag
     4081 ttatttatgt aatgagtagt ggtgctacac atgaagtagc atactcaaca tcaatttgct
     4141 tgatgatgga aatgcaatgg attaattctg gtaccttcca ttcaggagaa tttttccacg
     4201 gaccattcga aattgtggat aaagacgtac cgtttatatt attaatgaat gatggaaaaa
     4261 ctagaaatat agatgctcga gcattaactt tccttgaacg ctttgatacg aaaacagaag
     4321 ttgtagatgc cttggattat ggcttgtctt cacatattgc taaagaagtc ttagactact
     4381 ttaacccatt cgtgattact gcagtattta gagtttatgc agaagaattg tcagaagcaa
     4441 gagaacatcc attaactaag agacgttata tgtggaaact aacttattaa aaaatagatc
     4501 aaactaaata aggtggcttg agaaattaag ccaccttgtt ttcttcaatg tgattttata
     4561 catatggtaa aataactagt acatattgtg aaagcaggtg gcaagatgca gcgattaaat
     4621 gactatcttt atcaactaac attgcttttg aaatctacgc cttcagataa ttattcagct
     4681 cgcagtattt cgcaagcttt acagttgaat agaagtacaa tcagtagcta cttaaatgaa
     4741 ggtgttcgtg aagggctttt cataaaagta aaaagttacc cggttttatt tttacataga
     4801 acagctcttg aagaactaca tatcacactg aataactccg aaatagaatc aattgaaagc
     4861 ttgttaacaa tttctcaaaa acccgcatta gatcaagtaa ttggctctaa aggaagtttg
     4921 aaagaagcaa ttgatcaaat taaaacggca gtcttatatc ctggaaaagg gttgccttta
     4981 ttattgatcg gcgctagtgg atcagggaaa acctttctag cgaataaaat atatgaatat
     5041 gcagtagaag aaaaggtcat tcacacatcg gcacctttca tagattataa ttgtgcacaa
     5101 tatgtgagca atccagagtt actatcctct gctttatttg gctacacgaa aggagcattt
     5161 accggagcaa gccaggagca tactggtttg ctagaaaaag ccgatggagg agtattgttt
     5221 ttagatgaag tgcatcgctt atctgaagaa gggcaagaga aattatttac atttatggat
     5281 acgggtgaat tctctcctat gggggataat agtattcgga aaaaagccga tgttcgatta
     5341 gtctttgcaa caacagaaaa tatatatacg actttcttac caacttttct taggagattg
     5401 ccagttattg ttaatctacc tagatttcaa caacgtccgt cgtttgaacg tctgtcattg
     5461 attgatgaat tttttgtttc tgagagtaaa attttagcta aggaactatc tgtttctgat
     5521 gcattgattc atttcttaat gaatagtgat tttgaaggta acgtggggaa tattaaaaat
     5581 attatcaagt atgcttgcgg aaacgcatat atccaccaga agagtcagca aacaattcaa
     5641 gttaaattat tggatatgcc tttagagtac agttataaat tcaaggagca actaaataaa
     5701 cccagaaaga aaagagcaga tcgaatctac tatccagaag aaacacgaca agtgcaacta
     5761 gaaagaaaca atcagctttt tgttcaattt tttgaccaat tacttactgg attctctgaa
     5821 gtgattgaaa ataacaagga tattaaacta tttttagaag aaatggttac caaggtaaca
     5881 caagtaatgg atacgcttat ttttcaagag gattacgaaa aagagcagtc tttatacgcc
     5941 attctaaact atcatattcg tcaaagtatt gattttatgc gagaaagcta cgggtttgaa
     6001 caagatggta accgggtagt cgctttggcc aactatctat atgtcaagga taatcaagtg
     6061 atttttgaaa atagtcttca agaaaagaaa accaaagatc agcttaacga attttttgct
     6121 aatgttcttg aaacccctta ttggtatgca aaaaaaatct taagcctttt atctgagtgt
     6181 ttagatcaac ctgtgtatga agaggacatt ttctttatta cgctatattt ttatagtttg
     6241 aatgtcacga atgttaaaac aggtattaag agtattgtgc tagctcatgg ttattctaca
     6301 gctagtagta tggcgaatgt tgccaaccgt atgctgaata agaacgtttt tcaagcttat
     6361 gatatgcctt tagatattac attagagaaa attgaagcaa aattgattca attccttgga
     6421 gattatcgaa cagattcagg cttgatttta ttggtagata tgggttcact aaaccaacta
     6481 ggcggtttat tagtgaatca tctaaatgga ccactgttaa tcattgatca tatcaataca
     6541 ccgttattat tggaagtcgg ccaacaagta ttaaacaata aaagtatcac cgaaatagga
     6601 gcagaaattg aaacaagtct tactttcaaa aagcagttac tacttcccaa gaaaaagaaa
     6661 aagaaagcca tcattacttg ttgttataca gggattggta gtgcgaccca gattcaggag
     6721 attttaacga aatgcttgaa agatgcagtt agagaattag taattattcc gtatgattac
     6781 aaaaagctgt tagaaaacaa gaattttgag actccttttc aattatacga tgtcatcatg
     6841 attgtaggta cagaagatcc caaaattaat cagattccat atattggatt agatcgcctg
     6901 attaatgggg aagcaattgg cgaatttgtt cattacttgg aaaaagagct gactattgaa
     6961 gtgaacgatt tacaaaaaga attaattttc aatttttcaa ttagtaaaat tgtcgaaaat
     7021 ttaaccattt tggatccaga taaggtgcta tcttttgtac aaaaagcaat taaagaatta
     7081 tcgaagttat taaattttga tttttctaat aatcagctgt ttttgttgta ccttcactgt
     7141 agttgtatga ttgaacgaat tgtacgtaaa gaaagtgtgg atgagcaaga ggacattgaa
     7201 gaatatatgc aagcaaatgg agaaataatg gataaaattc atagcgcttt ttttgagatt
     7261 gaaagggaat acacaattga aataccagat ttagagttgc gattattgag cgatattgtt
     7321 caaggatagg agtgaattcg aatgacaatg ggagtaattt ttgatatgga tggggtactc
     7381 atagacagcg agacatttta ttttgagaga agaatgaact tctttcaaga actggagata
     7441 gatccaggat caaaccagat tgatgattat gtggggaaaa cagaagctgc aatatgggaa
     7501 acattagttc ctgaggacaa atcattaaga gaggaacttt atccgaaata tgtagattat
     7561 cgaaaaacgc atccaattga tttcgctaaa gatttacgaa aagaagtgaa accgttactt
     7621 gacttcctca agaagcggga tataccattg gcactggcat cttcttctcc agttgttgag
     7681 atagagagta tgctcattca atgtgaactt actgaatatt tttcctttgt tataagtggt
     7741 gagtcattaa aacaaagcaa accacatccc gaaatatatt taaaagcgaa acagcaatta
     7801 gactgtgact tctttattgc agtagaggat tcaacgattg gtattaaatc agcaaaggca
     7861 gcaaatatct atacggtggc actaaaacaa ccaatgcaaa tcgatcagag tgaagcagac
     7921 atacaaattg aaagtctaca agaactggaa caaattgttt tagaaaaagg ttagtgaatt
     7981 aatggaaata aggctatata tctgtgctag ctattttgac taaccaaaaa aacttgctat
     8041 aattcaggtg tagtaaaagg tgctggtaac accttttacg aaaatgcttc ggcagtgata
     8101 atgggattgg ctttttaagt tttttatttt gttcgcaatc cctaaggtca tgtgaatgat
     8161 cctagggatt gctagaatat tttgcaacat tctatctatt tcagaacgta accttcccca
     8221 gttcattggg attcattagc atacaaccaa catttcaaaa agaaattgca ctacaccatt
     8281 attagctatt ttgactaacc ccaaaaaact tgctataatt caggtgtagg taaaaggtgc
     8341 tggtatcacc ttttacgaaa ctgcttcggc agtggtaatg agtgtggctt aaaggactag
     8401 tcctttaagc tttttacttt gttcgcaatc tctaagatca agttaatgat cgataagatt
     8461 gctagaatat tttgcaacat tctatttcag aacgtaacct ttcccattcc actgtgattc
     8521 attggcaacc ctcctcacaa ccaacgtttc aaaagaaatt gtaaagttgt tggggtacca
     8581 cgaccgaaca atactacacc tgaatgatag taagttgtct cattaagtat agcatatcct
     8641 ctttttgggt aaatagaaat cggttacatt ttttatccaa gaccaagttt tttcatttgg
     8701 tcttatttgc tatacccaaa caattccgca gtatagtcga cggtattgat tttatcaggt
     8761 gagtaataga aacttgtttt ccttccccaa aacattacct ataaaggaga aaaaatggta
     8821 tcgtaattat ataggtatag gatgaaattt ttttctaaga ggagggttgt tgatgaaaaa
     8881 tttacagtta aaatttattg ttgatccatc gattgtacgc tggtttcgga ttatcaatca
     8941 atttgagcgc aatcaacttg ccacaaaagg agaattagca aagagtaatc atgtatctga
     9001 acgaaccatt caaacagatg tcaataaaat gaaggactac ttttctgaaa gtgttcaatt
     9061 tgtttcaacg aaaagtgggt attcttttca gaaggaaaga ccggttcttt ttctcaagca
     9121 gaaggagcaa ctactggaga acgaaatttt atttgagttg ttagggaatg tcttttatgg
     9181 cgaattggaa gatatgacgg agctaattga tcgttttcat ttatctgaag cgacttttcg
     9241 tcggtatttg aagcagattc aaccagtttt ggaagaatac ggcttagaat tgagtcttta
     9301 tcctcttgat ttaaaaggag aagaggcaaa tattcgcaag ttttttaaag acttctatta
     9361 tgaaggggag atgacgcccc atactcttgt tccaccaagg gatcttcatg aacttgtgca
     9421 agctacattc tatgataaat ttgagtattt ctcgattgga acagggactt ctcctgctga
     9481 attttattat agtttgtata ttgcgattga gcgtgtgaga caaggaaaaa cgatagccat
     9541 tcctcaaggt ctgattgagc gagtaattgc tagtgagaat tttcgcttaa tgtattcctt
     9601 gaaagaagcg attcaaacaa attatcaagt tgctttatca gaagaggagt tttgttggtt
     9661 gtatt
//
LOCUS       DAYYEF010000081         9442 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000081 DAYYEF010000000
VERSION     DAYYEF010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.085"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            59..205
                     /locus_tag="ACHA1B_002553"
                     /pseudo
     CDS             59..205
                     /locus_tag="ACHA1B_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_process: GO:0008219 - cell death [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            282..611
                     /locus_tag="ACHA1B_002554"
     CDS             282..611
                     /locus_tag="ACHA1B_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFM8703279.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            601..888
                     /locus_tag="ACHA1B_002555"
     CDS             601..888
                     /locus_tag="ACHA1B_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFM8703280.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1174..2031
                     /locus_tag="ACHA1B_002556"
     CDS             1174..2031
                     /locus_tag="ACHA1B_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HFM8703281.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYVEVE"
     gene            2032..2580
                     /locus_tag="ACHA1B_002557"
     CDS             2032..2580
                     /locus_tag="ACHA1B_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703282.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            2840..3301
                     /locus_tag="ACHA1B_002558"
     CDS             2840..3301
                     /locus_tag="ACHA1B_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermophilic serine proteinase"
                     /protein_id="HFM8703283.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRTNESDYNKRDQVLL
                     VKLNEEISVEEAVRTFNASDMVNYAEPNYVVELEPLNDVEEPNTTDSLGNR"
     gene            3345..3431
                     /locus_tag="ACHA1B_002559"
                     /pseudo
     CDS             3345..3431
                     /locus_tag="ACHA1B_002559"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(3397..4467)
                     /locus_tag="ACHA1B_002560"
     CDS             complement(3397..4467)
                     /locus_tag="ACHA1B_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008134 - transcription factor binding
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HFM8703284.1"
                     /translation="MKNDIVTYANTKCEEIGISNLEECFFDTNDLSQFLRTGRTNASK
                     LANDLVAKNVLFKINTRPVLFAIKERFEEHFLIPVKDVYESISELKTDLEPNSTDSIL
                     QKMIGYDMSLSDAVEQMKTAVFYPGRGLPMMITGDTGVGKSFFVHTAYQFMKKVNVIH
                     ENAPFKVLNCAQYHNNPELLSGILFGYVKGAFTGADEDRNGLLQDADGGVLFLDEVHR
                     LPPEGQEKLFVYMDGGTYSRVGETIHHASNVRLVFATTEGKEDFLETFMRRIPIHIHI
                     PNIEERGILEKNKLSKILSLAKAKTLARLLMFLLKSLVLHKYSQNILNYYFLEKSKKN
                     RIPNFHLHFQKDLHVDNQFLNQ"
     gene            5069..6913
                     /locus_tag="ACHA1B_002561"
     CDS             5069..6913
                     /locus_tag="ACHA1B_002561"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015573 - beta-glucoside transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA];
                     GO_process: GO:0015759 - beta-glucoside transport
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucoside-specific PTS transporter subunit
                     IIABC"
                     /protein_id="HFM8703285.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            6969..8435
                     /locus_tag="ACHA1B_002562"
     CDS             6969..8435
                     /locus_tag="ACHA1B_002562"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HFM8703286.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            8472..9314
                     /locus_tag="ACHA1B_002563"
     CDS             8472..9314
                     /locus_tag="ACHA1B_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFM8703287.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         3246 a         1442 c         1906 g         2848 t
ORIGIN      
        1 agcttaaatc atagataccg taagggattt tattctttat ttaaaacttt gcaacagaac
       61 ccaatcattt gagaagttaa aacctacaca tgaaggtagg tattttagaa gattgaatag
      121 acaacaccgg gttgtttata aggtagatga agatgaacac gtggttgaaa tttattcagc
      181 aaggacgcat tacgagtcac agtaattact tgtaaataca ttatctcgtg gtataatgta
      241 tttactaagt aattacatac tgttagaaat gagggattta aatgattaca aaaacaagaa
      301 aacaaggcaa ttcaatcatg ttgacagtac ctaaagattt taatgttcct aatggagtcg
      361 aagttgaagc aaagttggta gagaatggta ttctttatga atttgttgaa ccacaaaaag
      421 aattttatga ttttagcgaa gatattttgt ctgatataat tgcagaaggc tacgataaag
      481 atgagattct tgtagaattt aagaatagaa aaaacaaaat gcattcttcc tttagagata
      541 ttgctgaaga tacacttact aattctaaag taatgactaa agaggagttg gcaacagaaa
      601 ttggcttatg aaatcgttcc ttcaaaacat gtcattaagt atttaaaaaa gctaaaagag
      661 aagccattga aagaaaaatt tttgaattta atttatgatg aaattgcgat tgatccatat
      721 aagggtgaac aaaaaactgg ggatttatca ggtatttggt ctagtgggtt caaatatgcg
      781 ggcacaacat atagagtagc ttacgagatt atagaaaaca aggttattcc agtattgtta
      841 tgtggaacgc atgaaaactt ttatgaacag ttgaaaaaat taatctagtg atttgttgtc
      901 gttcttaaga aggacggctt cttttttatc gaaaatctga ttcgtctaca tgactaaagt
      961 cgcgagtatt ctctgcttct cgataaatta aataacgtca ttactttgag gaaagctata
     1021 aatcaatata tttcagcttt tccttattta tgtactacct tttacttatt aattataagg
     1081 tagtacatat atatcttttt tttggtagta actaaaaata aatatgttat aatagtatca
     1141 aatgaatatt gctaaaagaa aagaggtagg aacgtggtag cgaagaaata tgtaatcggt
     1201 aattttaaag gtggcgtagg taaaagtacg tgcgcgcaaa tgttagggtt tgaatcagca
     1261 gttaatgaag gaaaaagaac cttgataatt gacttggata tgcaaggaaa tacttctgat
     1321 gtgatgaact taacgcatat gaacttcact aacgaagaag gaggcggaga aggtgaaccg
     1381 attgtttacg aaaatactgt gactgacgtg ttgataaaca atcttccacc taaagaggct
     1441 gtctataaag taatcaataa cctctatata cttccagcag acatgtcctt tgaaatgtat
     1501 gatgattgga tcaaagacca atataatgat tcattatccc aattcaaata tatgaaagaa
     1561 aagctagaac cattatttga tgagtttgac gtcatctatt tagatgtccc accttctatt
     1621 tctgtatata gtaaatccgc gatgtacatt gcggattggg caatcgtcgt cttacagacc
     1681 caagtaaaat cgatgagaaa tgcgatgcaa tatcttgagt atatggactt ttttgtgaaa
     1741 gaatttgata caaatttata tgttgctggt gttattcctt tcatgttgga aagcggtgac
     1801 gcagtagatc aggaaatgta taaacaagcc caagagattt atggggaaca tttgattaaa
     1861 aatgttgtac tcaaaaatgc gcgcttaaaa cgatacgacg gatcaggtat tacgatggag
     1921 aagacaaaga aaggtctctt aaaacaatgg gatcgcaaaa gccacgaatt atttatcagt
     1981 attttgaaag aattggaaga acacgagaat tggtatgtgg aggtggagta attggctgac
     2041 atcaaaggac ttgatatttt tgggaacaac aaaggactcg ccaaaataaa aaaagaagca
     2101 gaagcaaaga aaaagcagca agcaattaca ccatctgaaa ataagcaatt agaagtgcac
     2161 caagttcaag aaataaaaac ttcctccaat gttgaaagac agagtagagg aagaacaaaa
     2221 aaagttggcg caccaatcag aaagtttgat aaggtttatt ccaccaagca tcctttaaaa
     2281 ctgtcgactt tgttaaatgc gacttccaga gttttagtag aaaagtatga gactaatatg
     2341 acaagagatg aattgcttag aaaagcttta gatgagtata ttaaacagaa tcttacgcaa
     2401 gaagataaac aagatttgtt taatgacgtg gtgaaagaac tagacttgtt cagagaaaaa
     2461 tatccaattg ttccagaatt agatgatcgt ggagaaataa taagaactac cagtcagata
     2521 aaacaagata ccgaagactc actgcgcaaa gggtggggaa tgaataataa agttagataa
     2581 taatcaaaga agaactaagt aactaccttt aaacggtagt tacttagttc ttctttgatt
     2641 tgcgtgaaat agaggggatt tatttttctg gttacgtgat taaaaaatcc aaaaaatgag
     2701 cataggaacg gttatgattt tagggtgtgt tttaatgaga tattgtgatt tcattaataa
     2761 gtgtatgata atctgttgtt gagttagtaa ataagtaata gagctaactc taaaataaaa
     2821 ctattaggag gagatgtaga tgaaaaagtt taaaaagaaa atatatttag gattggttgt
     2881 tggggtgagt atgtttgggt tcatggctca tactaaacaa gtaactgcag atactaacca
     2941 aaaagaaagg attatgagcc aattagatga ctctcaaata gagtatgtac ccaatgagct
     3001 aattgtcagt ttaaaggcta cacaaagaat ttcaacagag aaaaataaac cgcaaaattt
     3061 attgggtgta aaagttatgg tggaaaaaga tttgactctt aggacaaatg aaagcgatta
     3121 taataagcga gatcaagtat tattagtgaa attgaacgaa gaaattagtg tggaagaggc
     3181 agtaagaaca tttaatgctt ctgatatggt caattatgca gagccaaact atgtggttga
     3241 actagagccg ttgaatgatg ttgaggagcc aaatacaact gattctttag gaaatcgata
     3301 acgatcctaa ttggagtaaa caagctaatt taagagagat tagcatgcca tccgcttggg
     3361 aagaaaccaa gggttctaag gatgtgaagg tagcggtcat tgattcagga attgattatc
     3421 aacatgaaga tctttctgga aatgtagatg aaagtttggg atacgatttt ttttactttt
     3481 ttcaagaaaa taataattca gaatattctg actatattta tgcaacacta gtgactttag
     3541 gagaaacatc aatagccttg ctaaagtttt tgctttcgct aaagagagta ttttcgataa
     3601 tttgtttttt tctaaaatac ctcgttcctc aatatttggg atatggatat gtatagggat
     3661 tcttcgcata aaggtttcca gaaaatcctc tttgccttct gtagtcgcaa aaactaaacg
     3721 tacattggag gcgtgatgga tagtttcacc gactctagaa taagttccgc catccatata
     3781 aacaaatagt ttctcttgcc cttcaggagg caatctgtgt acttcgtcta aaaacagtac
     3841 tccaccgtct gcatcttgca acaatccatt tcgatcttca tctgcgccgg taaaagcacc
     3901 tttaacatag ccaaatagta tccccgacaa taattcagga ttattatggt attgcgcaca
     3961 attaagtact ttaaaaggag cattctcatg aataacgttc acttttttca taaactgata
     4021 agcagtatga acaaaaaaac tttttccaac tccagtatct ccagtgatca tcataggaag
     4081 ccctcttcca ggatagaaga cagcagtttt catttgttcc accgcatcgg ataagctcat
     4141 atcataccca atcatctttt gtagaatgga atctgtagaa ttgggctcca agtctgtttt
     4201 taattcagat atactttcgt atacatcttt taccggaatc aaaaagtgct cttcaaagcg
     4261 ctctttgatg gcaaataaca ctggacgagt attgatttta aatagaacgt tctttgcaac
     4321 taagtcattg gcaagtttac tggcatttgt tcttcccgtt cttaaaaatt gcgacaggtc
     4381 atttgtgtca aaaaagcact cttctaaatt actgatgcca atttcttcac attttgtgtt
     4441 tgcataagtc actatatcat ttttcatctt ataaacagtc ctttctaaac ttctatccct
     4501 taaataaata gcaaaaaaaa ggaagcaata tcgatatgct gtcctcttaa tttaataaag
     4561 cgctaatcta attcactgta ttatcatttt ttagtagtat agcacaatta tgaatgcctt
     4621 ttctttatat caaataaagt ttatataaaa aacctcatcc tgcaagaaag aaaaaatgaa
     4681 cccattcttt ttatactagg tcttaaaaag acagaacatc tgctagaaga tagaagagaa
     4741 taagagttat atatgttgga agatattctt agaaaaaaga caaaactttt agaacacgaa
     4801 aactatattg aacgaataaa atgaaaaaat gattaaaaaa tcattttatt atttacgttt
     4861 acattctaat atgttaaatt gaatataact taaacaggca tgtgactggt aatgcaggca
     4921 ggacctaaat aagttgaata acaatgtatg cgtttcaata cacgtttgcc ttgttgtcaa
     4981 tttatttagt ttctgcctgt tttttgtgtt gaggatggcc acttcgactc aaaagttcat
     5041 cactcaaaaa agaaaagagg gaaacaccat gaattacaaa caaacagcag aagaagtatt
     5101 gcagtacatc ggtggggaag aaaacatatc ccatttggag cattgctcaa ctcgtttacg
     5161 ttttacgtta aaagacaaca gcaaggtaaa tatgagccag ttagaaaaag tggatggcgt
     5221 tatgggcgtt cgccaaaatg tgcaatgcca agtaatcatt ggaaacgatg ttgttgaagt
     5281 gtatgatgaa gtgaaagcgt tattaggtga caatgtttca aatactgaag aagcaccaaa
     5341 acaaaaacaa aaattaggtt cagttctatt agattttatt atttctattt tccaaccttt
     5401 aattcctgcg attgcaggtg gaggagtatt gaagtccttg ttgctactag cttctatctt
     5461 agggctgatt agtgaccaat ctcaaaccta tcagatttta aatttggtcg gcggggcacc
     5521 gctttatttc ttgcctattc tggtggcaat gactacggct aataaattga aagtcaatca
     5581 attggttgca gtatctgctg tcggtgcatt gatccttcct gaaatgacag ctatgttggc
     5641 ggaaggtgct acattcttat cttttggatt ggataatata gcgtatgcat ctcaagtatt
     5701 cccagccatc ttaactgttt tattttatgc tcaacttgaa aaatggttta caaaagtttc
     5761 accaaaacca attcgtattt tctttgtacc tatgatgagc ttattgatta cagttcctat
     5821 tgctttgttg cttctaggac cattaggtta taatgtagga acagctttct cttctatcat
     5881 tgtgtctttg tacaatcaat ttggatgggt tgcaaccgga gtcttagcag ctgtactgcc
     5941 attaatggtt gtaacgggta tgcataaagc aatgatccct tacgctgttt catccatgag
     6001 tgaattgggt gcagaacttc tttatctccc ggcttcattg gcacacaata tttcagaagc
     6061 tggcgcatgc tttgctgtca gtatcaaaac aaaagacaaa aaattgaaat ctacggctgt
     6121 ttctgcgggt atatctgcat tattcggaat tactgaacca gctctttacg gggtaacgat
     6181 tctgcacaaa cgtgttttat atgccgttat gttttctagc ctgatcgggg gagcatttgc
     6241 aggaatcgtt gcacttcaag cctttgcttt agtgggtcct gggattgcaa gtatcacgat
     6301 gttcgctgac aaagctgacc caatgaatct ggtttgggca tttgcagtat cggggatttc
     6361 atttgtggtt gcttttgctg cagcgttggt tctttataaa gataaagaag ttgtcaatga
     6421 agttgaaact aagatggaaa cggccgttgt ttcagatgct gttctttcaa gtcccgtgaa
     6481 tggaaaagta atctcactat cagaagtaaa agacactgtt ttttctagtg gtatggtagg
     6541 tgatggagta gcaatcattc ctgaagaagg gatattagta gctcctgaag atggagaaat
     6601 cacaatggta tttgaaacga agcatgctat tggtttaaaa acggctaatg gtgcagaact
     6661 tctttttcat attggtattg atactgttca gttagaagga aaagggtttg aggcatttgt
     6721 tcgttctggt gaaaaagtag ccaaaggaca aaagctgatt gcatttgata ttgatttaat
     6781 caaagaagca ggattcgacc ccacagttat ctgtgtggta accaataagg ataattacac
     6841 tatccgttca tttaacctag aaaaattggt aaccaatgat agtgatctct tagctatcag
     6901 tccgatagct taaacacaag atagtgaaaa aaaatatatt gaatgaagga atagaggaga
     6961 atagaataat gacaaacaca acaagttttc caaaaggatt tttatggggc ggcgcgatag
     7021 cagcaaatca agtagaaggt gcttggaatg tagacggtaa aggtctttca gtagcggata
     7081 tggctactta taaaccaaat ttagacaaca aagattttgc tgctcatatg catgtcaccc
     7141 tgcagtctat aaaagaagct agtgaagaca aatctgataa atggtaccca aaaagaaggg
     7201 gcgttgattt ttatcatcac tataaagaag atttagcttt atttgccgaa atgggcttta
     7261 aaaccttgcg cctctctatt gcttggactc gcttgttccc tacaggagaa gagctggaac
     7321 cgaatgaaaa aggggttgca ttttatgaaa acgtctttaa agaaatgcaa cgtttaggaa
     7381 ttgagccgat tgtgacacta tctcattatg aaatgccatt agctttagca gttaaatata
     7441 atggctgggt ggagcgtcga gtaattgatg attttgttcg cttcgctaac gtttgttttg
     7501 atcgcttcgg caaatacgta aaatattggc tgacatttaa tgagatagac agcatccacc
     7561 gtcatccatt tacaacagct ggaattatcc aagagaaaag cgcagaaggt caagaagctc
     7621 aagatatcta tcaagcattg catcatcaat ttgttgcgag tgcgttagtg acaaaagatg
     7681 ctcatgaaaa aattccagga agccaagttg gttgtatgtt aacgaaattg atgacttatc
     7741 cattaacttg cgcaccagaa gacgttgagc tgaccttgaa aaagaactta gaaaataatt
     7801 tttatgcaga tgttcaagtt aagggagaat atcctgctct aatcgaaaag gatttggaaa
     7861 atcggggaat tcagattaaa atggaagatg aagatcgaga aattttaaag aaacataccg
     7921 tagattttgt ttctttcagc tattacatgt ccatggcaga atcagctgat ccaaacgcag
     7981 aacgcacacc gggaaatact gttttagggg ttaagaatcc tcatttgcct tcaacagatt
     8041 ggggctggca aatcgatcca aaaggtttga aaatttcgtt gatcgaactt tatgatcgtt
     8101 accaagtacc gttgatgatt gtggaaaatg gtatgggagc agtcgatcag gtagtagatg
     8161 gtaaaatcca tgatccgtac cgcatcgact actttaaagc acacttccaa caaatgaaag
     8221 aagcaatcga tgaaggtgta gatttgatag cttatactag ctggggacca attgatttag
     8281 ttagtgcagg aacttctcaa atgtctaaac gatatggatt tatttatgtg gatgcagacg
     8341 atgaaggaaa tgggacatat aaccgcttga aaaaggattc gttcaactgg tacaaagaag
     8401 tgatcgaaac aaacggtgca tccttattcg agtagtctcg atctttttaa gcagcgatag
     8461 ggggataatg agtgatttca ataaaaaaag tattgaattc aagtgtggta cttgttgaag
     8521 aaaatggcaa agaaatgatt gcattaggta aagggatagg ctttggacag aaagctgggg
     8581 atgaaatatc aggagataaa gtagataaaa tatttctgcc ttttgaagaa aagaaatctt
     8641 cacaactatt agagttagtt gaagaaatac ctattgaatt ttttgaaatc actcgtacta
     8701 tcgtttttga agcagaaaaa ggattagata aaaaactgaa tcctggagtc tatttaacct
     8761 taacagacca cctgcatttt gcagttgaac gcgcacaaaa aggggtaaat attgcaaacc
     8821 gtttgtactg ggaaataaaa atctactatc ccaaagaatt tcaaattggg aagtacgcac
     8881 tcaccctttt gaacgagcaa tatggaattg atcttcctaa agaggaagcc tcaaacattg
     8941 ctttccattt gatcaatgca caatcggaag atcctgatag cggcgctgga ttcaagtatg
     9001 caaaaatgat cggcgggatc gtcaatttgg tccggtattc gttgcagaaa gatatcgata
     9061 ctaattcgat ccattatgcc cgcttcatta cacatgtacg tttctttgta gaaagatatt
     9121 attctgatgc tttgttggat gatggtgagg aagaattcta caatcaaatg tggatcttat
     9181 acccgtctgc catggaaagc gcagctaaga tcaaagacta cattgaaaaa gtttatcata
     9241 aaacaattcc gaacgatgaa gttgtatacc taggtgtcca catcaatcgg ttgatgaaac
     9301 atgctaatgg gtgagcgctc agtaatacta ttgatgcttt taaaatcttt agagatggat
     9361 tatagtaaaa acaaggtgat ttccagctgt ttgttatcta taagagacat ttaaaaagga
     9421 ttaacgtaag ataataaaaa at
//
LOCUS       DAYYEF010000082         9246 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000082 DAYYEF010000000
VERSION     DAYYEF010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.086"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..225
                     /locus_tag="ACHA1B_002564"
     CDS             <1..225
                     /locus_tag="ACHA1B_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703288.1"
                     /translation="KTTEFDILHALMSTPNKVFSRSDLIEKVKGIEFDGLDRSIDSHI
                     KNLRHKIENDAKSPMYILTVHGTGYRFGGH"
     gene            225..1618
                     /locus_tag="ACHA1B_002565"
                     /pseudo
     CDS             225..1618
                     /locus_tag="ACHA1B_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294791.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            1633..1839
                     /locus_tag="ACHA1B_002566"
     CDS             1633..1839
                     /locus_tag="ACHA1B_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703289.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            1860..2456
                     /locus_tag="ACHA1B_002567"
     CDS             1860..2456
                     /locus_tag="ACHA1B_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HFM8703290.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
     gene            3408..4007
                     /locus_tag="ACHA1B_002568"
     CDS             3408..4007
                     /locus_tag="ACHA1B_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8703291.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            4056..4772
                     /locus_tag="ACHA1B_002569"
     CDS             4056..4772
                     /locus_tag="ACHA1B_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HFM8703292.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            4786..5565
                     /locus_tag="ACHA1B_002570"
     CDS             4786..5565
                     /locus_tag="ACHA1B_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HFM8703293.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            5648..6004
                     /locus_tag="ACHA1B_002571"
     CDS             5648..6004
                     /locus_tag="ACHA1B_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFM8703294.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            5994..6260
                     /locus_tag="ACHA1B_002572"
     CDS             5994..6260
                     /locus_tag="ACHA1B_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8703295.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            6419..6697
                     /locus_tag="ACHA1B_002573"
     CDS             6419..6697
                     /locus_tag="ACHA1B_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703296.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(6694..7375)
                     /locus_tag="ACHA1B_002574"
     CDS             complement(join(6694..7341,7343..7375))
                     /locus_tag="ACHA1B_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFM8703297.1"
                     /translation="MNHFKGKQFKKDVIIVAVSYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLDYLWKKKNRQSFYSWKMDETYIKIKGHWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFSVCTEI
                     RILLGIPA"
     gene            complement(7407..7568)
                     /locus_tag="ACHA1B_002575"
     CDS             complement(7407..7568)
                     /locus_tag="ACHA1B_002575"
                     /inference="COORDINATES: protein motif:HMM:NF013258.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HFM8703298.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
     gene            complement(7892..8224)
                     /locus_tag="ACHA1B_002576"
     CDS             complement(7892..8224)
                     /locus_tag="ACHA1B_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703299.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
     gene            complement(8388..9005)
                     /locus_tag="ACHA1B_002577"
     CDS             complement(8388..9005)
                     /locus_tag="ACHA1B_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703300.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            complement(9088..>9246)
                     /locus_tag="ACHA1B_002578"
     CDS             complement(9088..>9246)
                     /locus_tag="ACHA1B_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HFM8703301.1"
                     /translation="RRNKFYRSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGIPA"
BASE COUNT         3263 a         1440 c         1654 g         2889 t
ORIGIN      
        1 aaaacaactg aatttgatat tctacacgct ctaatgtcca cacctaataa agtcttttct
       61 cgtagtgatt tgatagagaa agttaaggga atagaatttg atggactaga taggagcatc
      121 gattctcata taaaaaactt aagacataaa attgagaatg atgctaaatc acctatgtat
      181 attttgacag tccatggtac aggatacaga tttggtggcc actaatgaga aaaagaacga
      241 taaaaactca attagctgtt tcctttttag caatcgcaac attaataata ggatcgatta
      301 gtttagtcgc attaagtttg atgaacaatc attttagtaa atacgtggaa gagcggcaag
      361 aagatttgtt gaatcagtat gtatatacaa ttgatttatt gtggttaaat agtggggaaa
      421 catggaatag tgaagaactt gcagcactat ctgagaaagt attagagaat aatatttatt
      481 tttctataga agacgaacaa ggcaacatgg tttgggaact tactggaaaa gatttgaagt
      541 cagcacagga gaaactgaaa aaaatgcatt gaaagtttct gagaaaaaca gtgtgaaact
      601 agacgaaaca atagaagtga aaaagaagtt aattaatgat ggaaacgagt ttggaaaagt
      661 aacgttttat tatttcggac cttttgctta tacagagcac gatgccttgt ttatctccag
      721 tatgaaacaa agtttaatgt atgttgcaat tgcagctctt cttgtatcat tcatacttgc
      781 ttcgtggatc tctgctagat taggattgcc actaaagcat gtaagcgatt ttacacataa
      841 attaactcgt ggggaatatg ctgataaaat cccacaagaa acttcaatta ttgaaataaa
      901 ttccttaatt gattccctaa atgatttaag taatcagttg gagaaacagc atgggcttcg
      961 aaaaagatta actaccgata tttcacatga attaagaact ccattagcta cgcttaaagg
     1021 caatgtggaa ggaatgattg acggagtctg gaaaataact cccgagcgcc tacaatcttg
     1081 ttatgacgaa atagatcgtc taactcgttt aattggaaat atagaaataa tcaacaaaat
     1141 tgaagcaaaa tatgatcatt taaataaaac tgagtttaac atatataagt tgattgaatc
     1201 cgttattgaa aatttcgcca gcaaaattga gtcaaaaaac cttcatgttg aaatccaagg
     1261 ggataacatc aatatatctg cagataaaga taaaatgaac caagttgtta tcaatctttt
     1321 gaataatgct attaaattta cgcaaaagga gggaaccatt aagttttcta taagtaaaaa
     1381 taaagaccat gttcttttaa ttgttgaaga caacggcatc ggtatagaaa aagatcagca
     1441 acttcatatt tttgatagat tttatatggc tgacccctcc agaagtagag ctttaggggg
     1501 gcaaggtatc ggattagcta ttgtaaagag cgttattgaa gcgcataaag gtagtataac
     1561 tgtaaaaagt aaattaggtc taggaactaa atttgttata aagttaccat ttcaataaag
     1621 gaggagagtt atttgtttca aaaacagata aaaattgcta aactagtatg tgaatgttgg
     1681 gcaaaaaaaa tattttttca actgatttcg atagatagtg tcgaaaaagt tcatttagat
     1741 atcttatcaa attctgtagt aatcttttct aagaaggact tatcaatagc tacaattaaa
     1801 aaagaagttt ttggattaca aatttatgag atgacctaaa tgtgattaat taaaggagga
     1861 tgaagacagt gaaaaagatg acaaaattag tatttgcaag tcttggaatt attgtatttt
     1921 taggagcgtg tagcaatcaa agtgaatcga ataattctaa tagcacaaac gaggaatcga
     1981 cttctacagc gtctagtgaa atgaatagta tggagggaat gaatcacgaa ggtatggttc
     2041 cttcttcaat gaaagatgct gcgaacccta aattcccggt gggaagtaat gttatactgc
     2101 taggcgatca tatggaaggg atgaaaggtg caaatgctca agttgtaggg gcctttgata
     2161 ctacaatgta tgaagtaagc tatgagccaa aaactggggg accaatggtt aacaatcatc
     2221 gatgggtagt acaagaagag ttaaaagata ctgagactgt agcaaatgag ggcgatactg
     2281 ttatcttgaa tgccgatcac atggatggga tgatgggagc tgaagcaaaa gtagataaat
     2341 ctattacagg aactgtttac gttgttaatt acactccaac cgatggtcaa gaagaagtta
     2401 agaatcatat gtgggtaact gaagatgaga tggaatatga cgaaaataat gagtaatttt
     2461 atatactaaa ccaacaagct ggtacatggt cttcgtattc tcaacatgag gaatatgagc
     2521 tctttgttaa taaggactga tgagttgtgc aaaatcaaat ctgggtcaga acgaacctca
     2581 ttctggctca gatttttggc tcttcgacat ttagtgctgg tagagagaca actgaaaatt
     2641 tagtcataac cagttaggca gagtgcttaa ctggtttttg ttcgcattta ttattctttt
     2701 gatattggct gcttgccctt caattttatt tggtttctta atcaactctt catataaccc
     2761 caaatcatat attaatgagg tgcctcctat tcctataaat ctatctcttc tttaatagta
     2821 tgagaaaagt ctactcttgt agatttaaat tgtcaacaaa aaatttacag atgtaaatga
     2881 taagttgaat agagaaagat aaattatttt tttggtattc atataaggtt aattatgtat
     2941 tatcacaaaa tgattgttgt cgaataacta aaagtgtcaa aacaatgatg aaatcattta
     3001 gttcttataa attagacaag agaaaataaa tattccatat ctactttatt ggatccataa
     3061 catgactaaa ttctgaatac tttttaaagc ttatcatttg gtaaaactga atataagtta
     3121 attatataga ctgaaaattt tgaattttca gaatagaata acttaaaagt actgacaaat
     3181 tttttaaagg ggcaatatta atgttctgag ataatcaaat cttaccgaaa atatcaaaag
     3241 tccaatgtga cacaattgga ttttgtcaca ttcgttaaaa tcgctccatc cttagaggct
     3301 ctaataggaa atcacttttc ttttagcgcc ttttttctat agcttgttta aatgtgactt
     3361 attatctgtt ataatcgtat taagtaacat ttgagaggtg tctaaaaatg aaaagcgtgg
     3421 aaccgattcg cgacaaaaaa aagatcgatg ccatgaaggc cattttggct tccggaaaat
     3481 atgggcaacg aaatttggtg cttttttcga tcgggatcaa tacagcctat cgaatctccg
     3541 atttaagaca gttaaaatta agggatgtgc tagaaatttc ccgtgggcgg gtgatcgtca
     3601 aagaacgtct ggccatgaag gaacaaaaaa cggccaaaca caattcggtc ttcatttcga
     3661 acaaattgcg aaaagtgatt cttgattatg ttcaatccga atttcctgag cagttgcaag
     3721 cacaagactt cagcaagtat ttgtttccaa gtcgaaaagg agcagatacg cctttgaccc
     3781 gacaaagcct ttggcggatc attcatgaag caggaactgc agttgggtta aaagaaattg
     3841 gtccccattc gatgcgtaag acctttggct attttttata caagcaagga accaaaacag
     3901 agatcattca gtcgctgcta aaccattctt cacaacggga gaccttacgc tatattggaa
     3961 tcacccagga agacaaagat actgcagtaa agagtttgga tttatgacag aataatgccc
     4021 tatataatag aaggaaaaat tcaagaggtg agaaaatgaa cgaagaaaag cagcctaact
     4081 ttcctgataa atatcactta tctcgcaaag agtctgtgta tttattgaag aaaaacattg
     4141 tagaactggt gtataatgcg gggaaatttg aagggttaaa tacaacgttg ttacaaacag
     4201 aagggattat taagtataat cgggccaaca acgtggctgt agatgatgtc ctgaccgtcg
     4261 ttaacttaaa aagaggcttt gaaatgcttt taaatgacgt acaggagccc ctgttagaga
     4321 caagtaagcg gattaatcgg atcgttgcag cagaggatgc gctttttccc ggtgaaatac
     4381 gaaccggtgg ggtagaatta tcgacgattc aaggaagata tgtgccacca atgttaactg
     4441 aagacgaggt aaacaatcaa tatggtgaga taatgaatca agagatatca gatacggaaa
     4501 aagccctgcg actgtttcta ttcatttcga aaaatcaaat attctggaat ggtaatgtgg
     4561 gtacagcctt gttgattgcg aataagatta tgtttagcaa cggtttagga ctattatcaa
     4621 tacccgaaaa tgtatttatg aaatttaacg aacttttatc aaagtattgc aacagtaatc
     4681 tattagtcaa tgagtcaaat attatatcat ttttatatga acagtgtatc tttggtatta
     4741 attatttgaa aataatccaa catacaattt aagaggtata agtaaatgat gactatagac
     4801 gaagcaaaac aattagcaac ttatttttca gttggttcag cgggatatat tttagacttt
     4861 actaatgtaa cgtggaacat atttacaaag aaaatcgtag ggattgaaat acaaaatcat
     4921 tatgggggct caaagggagt atcctttcaa aagtttctgc ttgacgatca atttgatgat
     4981 tcgttaaaga atcggttaat ccaatcttta aaaggtatta tggatcgaga taaaaaatat
     5041 gaatctactg aaatgaatcc catagttcag ttgctttttg aggaagtatt taaagaagat
     5101 acttcaactg cattaagaaa aatgaaattt tcaagcgaga ttgatttact ttatattcgg
     5161 cagctaccca ttaggattca aacagatatt aaaaacaagg attttgactc tgttttgaca
     5221 aaagcaaata ctttaataga tgaagttcta aaatttatta ttgaaaatac cgaaggaccg
     5281 agtgttaata ttaatttatt taagtcaaaa gaattaagaa aagaagtatt tggccgcctc
     5341 aatattaaaa ctgaaaaaga tatggataat agaatcaaag cccttgttgg agcactcaat
     5401 acattatcag ataaaatact cgaaatgaga aatagtcaag gagatgctca tgcacatggc
     5461 tcaaatagaa tagtaattaa ggaagaagaa gcaattcttg ttgcaaattc ttctatggtt
     5521 ttgtgcgagt atgtgtttac taagtataaa ggattaaata gataataaaa tgcatatttt
     5581 atagtataca attcgaattt ttatgttata tactataata taaaatcaat atatgatata
     5641 attgggtatg gaaaaaatat cttttgaaac atttaaaaga cccaatggtc atgatgaatt
     5701 tttagaatgg ttggaaacat taccaaaaaa agatagtgcg aagcttttac gtacaataga
     5761 agaaacagaa aagaatggga tgctagtagc tcaacggttg aaatgggtga aaaaattaga
     5821 cactaatttg tacgaattaa gaagtaaggt aggatcaaac atccaaagag ccatctattt
     5881 ccatgtggac aatggaaggt atgtcattac tcacggattt actaaaaaaa cggagaaaac
     5941 accaataact gaactcaagc atgcaaaaga acttagagag gagtggttca caaatgatga
     6001 ttaaaaaatt gattgaagaa aagaaaaaag ataaagattt tgcagaagca tatgaccgtg
     6061 aaggaagaaa actcgaaact gcggttgctc tttatcatgc tcgggaggaa gcagggctaa
     6121 ctcaagcgga gcttgcacaa aaagcacata caactcaatc tactattgct cgaattgaga
     6181 gaggggataa cgtatctttc gataaacttg atgatatcgc cagggcatta ggtaaaaagc
     6241 tggtagtaga atttgcttaa aagcgagttg aaaatatatc tataataggc tcctaactaa
     6301 tcaattagtt tagtgggcct ttttttacta gatagataaa ggttgtacta tagtgtaaaa
     6361 gacaataaat tttatactaa aattacttta aagagaacta gagagaaagg tacaataaat
     6421 gaaaaccata aatcttataa aagtatttat agcatcacca ggtgatatag cagcaaaaag
     6481 gaatgaagta gaagaaacca tatatagatg gaatatagaa aatacagata atacaaaagt
     6541 gattttgatg cctatacgat gggaaactaa tgcgattcct acttatgtaa ataatagctc
     6601 tgggcaaagt gttattaata aacaaattgt agaaaatagg gttctgctgc aaagttttaa
     6661 aaataaaatc agtttttgta ttatttcttc attttaagct ggaattccca ataatatcct
     6721 gatttcagtg cagactgaaa agccgaagag agtgccttct tttcggcttt tcttgtagat
     6781 tcctcgaatg gtttccatcc ctttaattgt ggtggaagct gtacgtagac tttgatacaa
     6841 tttatgtcga cgttttatcg atcgatgatc ttgttctatt aaattgttaa gatacttcac
     6901 agttcggtgc tctgtcttag tatataaacc cacactctgt aactttctaa aggcggagcc
     6961 aagagaaggt gctttatcgg tcacaattgc tttcggctca ccaaactgtt tatggagtcg
     7021 ttttaagaaa gcataggctg cttgcgtatc ccgtttcttt cgtaaccaga tatctaaggt
     7081 taagccgtcc gcatcaattg cacgataaag ataatgccaa tgtcccttaa ttttgatata
     7141 ggtttcgtcc attttccatg aatagaagga ttgtctattt ttcttcttcc aaagataatc
     7201 gaggactttg ctgtactctt gcacccaacg ataaatcgta gtatgacaaa catttattcc
     7261 acgatcatat aacaattcct gaacttcacg atagcttaga ttgtaacgca ggtagtaact
     7321 aacagcgaca ataatgacgt cattttttga attgtttgcc tttaaaatga ttcattactc
     7381 tatcctctct gtcttttttc tcaattttac actaaaatag attttttgga aaactttgca
     7441 acagaaccac ttttcgtaat atcaatgtct ttattcgtat gatttttcgt tttacgatct
     7501 acatgatttt gaagtccatt taacgaccca actttatgct tttgtgttcg tgccaccata
     7561 taggccataa ctgtgtactt cctttcgtta aaattattgc gagaatcaca agctaaattc
     7621 ggaaaaacct ccatgtaagg tataacttac tagacttata ctgcgtaaag tctgtaagct
     7681 ctgccgaggg ctatatcggc ttaacagccg atgagaaact ccgtttctct caaacgaaaa
     7741 agcgaacgaa aaacgactgc cttcgcattc cttttttacg tccttttttc gttcaaaacc
     7801 attggctttt tgcgtcattg ttttcacaat ttttattccg caaaaaacca aaagtgaaaa
     7861 gtattgcttt tcacttcaac ccctcctcaa tttagttcac attttctgaa cgaaattgtg
     7921 ccataaattg agtcaaaccc ttaacatcat tcgtacgcca atatgcacca ttttcttgcc
     7981 aaactaatcc atctgcaaat tttcttagcg atactaaaac ctcatcattt actgaatgat
     8041 ttcttttatt tgattccaaa aaatctaatg cttcagcagg tgtcttaaag ccttcctttt
     8101 tacaatataa tttcgctaaa gaaatcattt ctttctgtct aatctgtttt cgtttcgctc
     8161 taatcttcgc ttcttttgct ttcaaatccg ccatttcttt tgccaatatt tctctattgt
     8221 tcattttgat tcctcctaaa aataaggcat atttctagtt taaaatattt attttacgaa
     8281 tagaggattt gaacaacgaa tgacacaaaa acaacaaaaa aagagcaatc atcataagat
     8341 gattgctcta aaaaactgta gtatttttgg ccaaattttt aattttttca atccaaatta
     8401 aaaatttggg atactctatt tttcaaaaaa cttctaaagg tttgctcaaa ttttaaaata
     8461 gtacgtctat caccagtaga accatagcgc atatttgcaa caagatcata agtgcataaa
     8521 cgaccattca tttttaattt aactttgaaa acaggcattg aagtacctga atttgtttct
     8581 aaaaaaaagg ctgcatattc atctggttct aatgaaattt tgttttgacc tcttatttgt
     8641 acctgttcaa acatctgttt ttcaacgttt tttgcagaaa aatcttcaat gactggagga
     8701 ttttcaagca ttttcaacaa tttaatctcc aatggttttt cttcgcaacc aaatacccaa
     8761 taataagatg gagaagtact gttaatttca tgactatcgt acaattcaac tctatgttcc
     8821 tttgaaaaat catcgaattc atttcgattc atttttttca ctattacttt ctcataagaa
     8881 ttttttttat caacaaacca gatccacata gatcctaaaa ataaaaaaat aaaaaataag
     8941 attccccaac ctaatccatc taaactaaat aatttagcaa agatttcttg tttaaatatc
     9001 cacaaaacaa ttttcctccc actttaaaat aatggttctg ttgcgaagtt tgaaaatcaa
     9061 acgcgccctc tctgaactcc aaatatctta ggctggtatt cccattaata ccttgatctc
     9121 agtagacacc gaaaagccga agagcgttcc atttcttcgg ttctttttat atattcctcg
     9181 aatggtctcc atccccttaa tcgtggatga ggcagtccgg agacttcgat aaaatttatt
     9241 ccgtcg
//
LOCUS       DAYYEF010000083         8796 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000083 DAYYEF010000000
VERSION     DAYYEF010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.087"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..209)
                     /locus_tag="ACHA1B_002579"
     CDS             complement(<1..209)
                     /locus_tag="ACHA1B_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703302.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISS"
     gene            complement(197..826)
                     /gene="pyrE"
                     /locus_tag="ACHA1B_002580"
     CDS             complement(197..826)
                     /gene="pyrE"
                     /locus_tag="ACHA1B_002580"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA];
                     GO_process: GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HFM8703303.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            complement(833..1549)
                     /gene="pyrF"
                     /locus_tag="ACHA1B_002581"
     CDS             complement(833..1549)
                     /gene="pyrF"
                     /locus_tag="ACHA1B_002581"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA];
                     GO_process: GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA];
                     GO_process: GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HFM8703304.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            complement(1546..2478)
                     /locus_tag="ACHA1B_002582"
     CDS             complement(1546..2478)
                     /locus_tag="ACHA1B_002582"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004152 - dihydroorotate dehydrogenase
                     activity [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HFM8703305.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            complement(2475..3251)
                     /locus_tag="ACHA1B_002583"
     CDS             complement(2475..3251)
                     /locus_tag="ACHA1B_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA];
                     GO_function: GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HFM8703306.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            complement(3305..6490)
                     /gene="carB"
                     /locus_tag="ACHA1B_002584"
     CDS             complement(3305..6490)
                     /gene="carB"
                     /locus_tag="ACHA1B_002584"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HFM8703307.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            complement(6495..7571)
                     /locus_tag="ACHA1B_002585"
     CDS             complement(6495..7571)
                     /locus_tag="ACHA1B_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004088 - carbamoyl-phosphate synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA];
                     GO_process: GO:0006541 - glutamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="HFM8703308.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            complement(7576..>8796)
                     /locus_tag="ACHA1B_002586"
     CDS             complement(7576..>8796)
                     /locus_tag="ACHA1B_002586"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004151 - dihydroorotase activity
                     [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA];
                     GO_process: GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HFM8703309.1"
                     /translation="EIWIEDGRIKAIGTGFSEAEFDEVFDAKGQLITPGLVDVHVHLR
                     EPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTAEKLRQVYDIIRKDAVVKVLQ
                     YAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAGTMYLAMKEAAKNNKALVAHT
                     EDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDLLLAEATGVHYHVCHVSTKES
                     VRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWKMNPPLRGREDREALIEGLLD
                     GTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQLIYTHFVETGRFTLEQVINWL
                     AVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKEDFLSKGENTPFIGWKVKGETQ
                     MTFVNGKLVWQKGE"
BASE COUNT         2323 a         2043 c         1594 g         2836 t
ORIGIN      
        1 gaagagatta ttctcttctt tctgctaacc agtcttagaa aaatgaattt taaaaaaatc
       61 aaaaactgat cacgatagaa gtttcttttc atacctgatg aaaagatgct tctcgcaatc
      121 agtttttgga tttttgctat tccaattgat gattctggag acacaaatcg gatttctcta
      181 tcttcatcaa gcgcgcttaa atctgccaat tttcaggatc ttttttccat tcttttagca
      241 gagttaattc ttgctcatcg atataacgat cttctaaagc tgcttcaatc aatacagaat
      301 aattggtcaa cgtcataaga gggatttcgg ctttttcgaa atttgctttt ccttttggca
      361 actcatacgt aaagatagcc gcaacaccaa ggatatccgc accttctctt tttgctgctt
      421 cagctgcttc caagacactt ccgcctgtag aaatcaaatc ctcgatcaca accatcttct
      481 gaccttcaaa tatacgtcct tcgatttggt tacctttccc atgatctttc gccttacttc
      541 gaatatagac cattggcaaa tccagtattt ccgctaccca tgcggcatga gggattcctg
      601 ctgttgcagt tccagcaatc acttgtactt cagggtaagc ttctttgatt ttgcttgcta
      661 atccttttgc gatctctttt cggacttttg gatagctcat cgtgattcgg ttatcacagt
      721 aaattgggct tttgattcca cttgcccatg taaaaggatt acttggattt aaaaatactg
      781 cttcaatttc taataagtct tttgcgatac tttgttcaac attcatttta ggttagctcc
      841 attctgtttg aatcgtttga tatgctttat aaggattagt tgactgagtg attggtcgac
      901 ctataacgat aaaagttgag ccgatctttt ttgcctgaga aggtgtgact actcttgtct
      961 gatctcctgc gactgttcct tctggtctta tacccggagt taagcaaaca aattcgtctc
     1021 ctgccatttc tttgatcgct tctacttccc aagcagaaga aaccacacca tctaatcctg
     1081 cttttttggc acagctagca taatggatca cacttttttc taaagaaact tcgattagtt
     1141 gatcggcatg catttcttct tcacttgtag aagtaagctg agtgatagct agaagtagcg
     1201 gacgttttcc accttctgga gtcccctctt ctaatcctcg cattgccgcc tccatcatac
     1261 gaataccgcc agcggcatga acacaggtga gatcaacacc aagctttgcc aatccccgca
     1321 ttgctttttc gaccgtattc ggaatatcgt gaagtttcag atctaaaaat acattatgac
     1381 cagcctcttt tagataacgt acgatttcag gtccttcttg gtagaacaat tccattccga
     1441 ttttcacaaa caatttttct tctttcggga aaaatcgaag aaagtcttct acctcttgcc
     1501 tagttgaaaa atctaatgca ataattggtc gttggtctag ttgattcatc gttcacgttc
     1561 ctctctcact tctttgatta atctttccag cgattcgatg cctagttcgc tcattcgcac
     1621 agggagctct ttaattagtt taggacagat atacggatcg gtgaaattcg cggtccctat
     1681 agctacagca cttgctccag ccataaacat ctcaagaaca tcatccactg tctgcacgcc
     1741 gcccatccca atgattggaa ggctggatat acttgctact tggtgaatca aacgaatagc
     1801 gacaggcttg attgctggtc cggagagtcc acctgtttga ttggctaaaa tcggttttct
     1861 tgtcttaagg tcaatccgca taccaagaag agtattgatc atcgtaaacc catctgcccc
     1921 tccagcttcg attgcctgag cgattggaac gatgtctgtt acatttgggg acaatttgac
     1981 atagacagga acagaagaaa ctttctttac tgcttgtgtt aattgaaaag caacatcaga
     2041 atctgttcca aaagcaattc cgccatgttt gacatttggg caagaaatgt tcagctcgat
     2101 tgctttcaca tttggtgctt cgccaatttt gctacaaact tctacatagt cttcttcaca
     2161 agcaccagca acatttgcga tgatgggtaa ctcattgtac tcctctaatt ctggaagaag
     2221 tttatgcata acaacgtcta gaccaggatt ttgcaaacca attgcattca acatgccaga
     2281 tggtgtttcc gccactcttg gcgtgggatt gccaaagcgg gcatttggag tcgttgcctt
     2341 gaccatgatc gatccaagct gattcaaatc atagtatttt ccgtattctt tgccaaaacc
     2401 gaaacagccg cttgccggca tgataggatt ttttaattct aggccaggaa gtttgaccgc
     2461 taaaggattc tcattcatat aattacctct cctattttaa aaatcggtcc ttcgtcacaa
     2521 actttcacac tttttgttcc tgtttcatct tccggcgtat gacaaacgca agcatagcaa
     2581 gcccctatcc cacatgccat gcgggattct aatgataact ggacattttg atgcgaagaa
     2641 aacagctgtt ccactgtctt caataacccg tttgaaccac atgcaaaaac agctgtaggt
     2701 tccgtcttcg ttcctaacaa taaattaccg acatttccgt gcataccgta tgttccatcg
     2761 tcagtagcga ttcttgtttc tcctagacga ttaaattctt tttcataata aacgacttca
     2821 tgtgtggcaa aacctaaaaa atgcgttggc ttaattcctt tttcgactaa ctgttttgat
     2881 aactcatata gaggagggac accgattcct ccaccgatta taaatacttc gtctcctgta
     2941 tgaagattgg acaaatcaaa accattgcct aaaggaccca tgacatctaa atggtctccg
     3001 gcagaaagag tagagaagac tctagtcccc tcaccttcca cccgataaat gatacggcaa
     3061 gtatttgttt cgtggtcgat atgattcaag ctaatcggtc ggcgtaatag caagtctgca
     3121 cgcggcacga gaatatgcaa gaactgtcct ggttgctgca tttcttttac tagatcacct
     3181 ttcaatgtca tttcaaaaat ctttggtgcc agctgttttt gctgaacgat ttccatcatt
     3241 tcttgtttca tctgtcccct cctgcaacgg tttttcgtct ttttgtctta acatgtgctc
     3301 gccgttaaat agggttagtt gaaaaagcac gggattccat cactcgaacg atcgcatctg
     3361 ctgtgtctaa agaagtaaac aatggaatac catgttcaac tgcttctctt cggatgatga
     3421 aaccgtcttt agaagcattt ccccgatctt tatcaatcgt attgacaacc acttgtgttt
     3481 taccatctct tattaagtcg actacatttt tttctgctgc ttcctcagaa attttcgcta
     3541 ctgtttcaac gaccagacca tttttttcga aataagcagc tgtatgtttc gttcctatca
     3601 gactatagcc aatttctgta aaacgtttag ctaattctag tgcttcttct tttgtttcgt
     3661 ccgcaatcgt aaataatacg gctccatatt caggcaagtg taatccagaa gcttcgaatg
     3721 ccttgtacaa agctttgtct aattgtctgt cagatcccat tacttctcca gtcgatttca
     3781 tttcaggccc taagtaagta tcaactttct gcaatttcgt aaaagaaaag acaggtgctt
     3841 taacatgaac ttcttttgtt tctggataaa gtccgttttc ataaccaagt gtctttagtt
     3901 tctctcccaa aatagctttc gtcgcaattt gtgccattgg aattcctgtc accttactta
     3961 agaatggaac agtccgactt gctcgaggat tgacttcgat cacataaacc tcattttcat
     4021 ggatgacaaa ctggatattc atcatcccga cacaattcaa acctaatgct aagcggatcg
     4081 tgtaatcttc gatcgttttc ttgatcgatt cagataatgt ttgaggtgga tacacagcca
     4141 ttgaatcccc tgaatggaca ccagcacgct caatatgctc catgatccct gggatgagta
     4201 ctgtttcacc gtcacaaatc gcatccactt cgcattcacc accaagcaag taacggtcca
     4261 ctagtactgg atgttctgga gatgctttca cagcatgttc catgtaatct tctaaatctc
     4321 gctggttttc aacgatttcc atcgcacgtc cgcctaatac atagcttgga cgaacaagaa
     4381 ctggataacc aattctcgaa gcgataacca cggcttcttc tttacttgta gcagtatccc
     4441 ctaaaggttg aggaatatcc aactctttca gcgcttgctc gaataaatca cgattttccg
     4501 cacgatccaa gtcttcgatc gttgtcccta agatttttac accagcagca gtcaaaggtt
     4561 cggctaagtt gattgctgtc tgaccaccaa attgaacgat tactcctatc ggctgttcta
     4621 gctcgatcac attcatcaca tcttcgaagg tcaatggctc aaaatataat ttatccgaaa
     4681 tagaaaagtc agtcgaaact gtttcaggat tgctgttcat gatgattgct tcgtatcctg
     4741 cctgctggat tgctttgaca gaatgcacag tcgcatagtc aaattcaacc ccttgtccga
     4801 tacggatagg accagatccc agtactagaa ttgagggctt ttctgatcgt gaactttcat
     4861 tttcatattc ataggaacta taaaaataag gtgtttttga ttcgaattcc gctgcacaag
     4921 tgtcaaccat cttatataca ggaatcaaat cattttcttt tctcatctgg cgaacggctt
     4981 cttcgtttat ttcccacagc tccgccactt ttttgtctgt aaaaccgttt tgtttcgctg
     5041 ttttcaatat cttgtcatcc aacggctgct gtttcaactg ctgttcgatt tctacgatat
     5101 gcaacagttt atctaaaaag aataaatcga tttttgtcaa atccgctaat tcttctatgg
     5161 tgtaccctct tctaatagct tcagctacat aaaacaggcg atcatcttgt gctcgaacca
     5221 ctttttggat taggtcatcg tccgtgatgt ctgccaactc aggaagttcg atatggtgtg
     5281 taccgatttc taaagaacgc acagctttca ataaagactc ttcgatattc cgaccgatag
     5341 ccatcacttc accagttgct ttcatctgcg tgcctaaaag ccgttctccg ttttcaaact
     5401 tatcaaacgg ccagcgagga attttagcta caacataatc taatgcaggt tcaaattctg
     5461 caaaagtcgt tcctgtaaca ggatttttca tttcgtctaa tgttaatcca agcgctattt
     5521 tagcagctag cttagcgatc ggatagccag tcgccttact tgctaacgca gatgaacgag
     5581 aaacacgcgg attgacttca atcacataat aattaaaact atgtggatca agagcgagtt
     5641 ggacattaca gcctccctcg atcttaagtg ctcgaataat cgaaagagaa gcatcacgaa
     5701 gcatttgata ttcatggtca gacaatgttt gactaggggc aaatacgata gaatcacctg
     5761 tatggatacc caccgggtca aaattttcca tattgcagac aacgattgca ttatcagccg
     5821 aatctctcat cacttcatat tcaatttctt taaaacctgc aatacttcgt tcaatcaaac
     5881 attgggtagc gggggaaaga cttaatccat tttctgatac gatacgtaat tcttcttcat
     5941 tttcacacat acctccacca gttccgccta aagtaaaggc tggacgaacg atgacaggat
     6001 agccgatttt atttgcaaaa tctacagctt cttctactgt attgacgatt tcagactcgg
     6061 ggattggctg attcaattct ttcatcaact gtttgaatag atcacgatct tctgcttgat
     6121 cgatcgcaga aagctttgtt cctagaagtt ctatgttcaa ttcttctaaa atacctgatg
     6181 ctgccagctc cattgccata ttgaggcctg tctgtccgcc taaagttgga aggagagcat
     6241 ctggacgctc ttttcgaaga atccttgata caaattcaag tgtgatcggt tcgatatata
     6301 cttgatctgc cacttcttta tccgtcatga tcgtcgcagg attagaattt actaaaacca
     6361 cttcatatcc ttcttctttt aaggcaaggc aggcttgtgt tcctgcgtag tcaaattctg
     6421 cggcttgacc aatgatgatc ggaccagatc caatcaccat aattttcttg atatctgtac
     6481 gtttcggcat ctgtttactg ctcctttcct gcgtccatca tttccataaa ttcatcaaat
     6541 aaatgtagtg catcatgcgg accaggggca gcatctggat gaaactgcac actgaaagcg
     6601 ggataatctc tgtgtttgac tccttctact gttccgtcat ttacttctac atgagttacg
     6661 atgagttttt ctggatcaat cgtggcttca tcgactgcat agccatgatt ttgagaagta
     6721 aaatcaattc ttccggtcgc tacttctcgt accgggtgat ttaatcctcg atgtccgaat
     6781 ttcattttat aggtatctgc accgttggct aaagcaaata actggtgacc gagacaaata
     6841 ccaaaaatcg gtacttttcc ttggattttt ttgatcattt cgattgcttc tggcacatct
     6901 tttggatcac caggtccatt cgtcagcatg actccgtctg gtgatagcgc taaaatcgtc
     6961 tcggcatctg tgttataggg aagtactgtg aggttacagt ttcttttact caattctcgt
     7021 aaaatactat gtttcaagcc gaagtcaatg acaatgactt tccgacctgt tcctggactt
     7081 ggataaggtt tgttagttga gacttgctgc acttgattgg ttgctagaac ggttgctttc
     7141 agctgatcaa atgcatgttc gaaggaatct ccagcatcaa ctatactagc tttcatcgtt
     7201 ccgacttcac ggattttgcg agtaagggcg cgcgtatcga tacctgatat tccaggaatt
     7261 cctttttgtt tcaaaaatga atctagcgtc atttggtttc gccagtttga agctacacgt
     7321 gcatgttctt ttactactac tcctttgcat gttggagaaa tcgattcata atcatctcta
     7381 tttaccccat aattacccac cataggatag gtaaatgtaa tgatttgacc gttaaaactt
     7441 tgatcagtga tagtttcttg ataaccagtc atacttgttg taaaaacgat ttctccgaag
     7501 acactagcat ctgcaccaaa agcctttcct tcgaaaactg ttccatcttc taatataagc
     7561 aaacgttcca tacttttatt ctcccttctg ccacacaagt tttccgttga caaaagtcat
     7621 ttgtgtttcg ccttttactt tccagccgat aaaaggtgta ttctcccctt ttgataaaaa
     7681 gtcttcttta tcgatcgtgc aagtttgtgt aatatcaaaa actgctacat cagcgggggc
     7741 accaaccgtt agcgttcctg cattcaaacc aaaaatctca gccggtttaa ctgccaacca
     7801 attgatcact tgttccaacg tgaatcgacc agtttctaca aaatgagtat agatcagttg
     7861 aaacgctgtt tcgcttccta cgataccaaa tggtgatttc atgaaacttt ggcttttttc
     7921 ttctaatcca tggggggcat ggtctgtagc gatgcaatcg atcgtaccgt caagcaagcc
     7981 ttcgatcaaa gcttctctgt cctcccgtcc tcttagcggc gggttcattt tccaaaagcc
     8041 gaaatcttcg ggaatatctt cgtcgatcaa aataagatga tggggtgaaa cttctgctgt
     8101 tacgtggatt cctgcttttt ttgcgtctct gattacacgg acactttctt tagtagaaac
     8161 atggcaaaca tggtaatgaa caccagttgc ttcagctagc aacagatctc tagcaatttg
     8221 agaagactcg gttacgctta agatcccggg aagaccaagt tcttctgcct tcttgccagc
     8281 gtgcataacg ccgccaaata ataaagattc atcttctgta tgggctacta gggctttatt
     8341 gttttttgca gcttctttca tagccagata catcgtccca gctgtttgga cacctacacc
     8401 gtcatttgtg aaagcaaaag caccttcttc aatcagtgct tcttgatcaa ctaatttctc
     8461 acttcgcaga ttttctgtga ttggcgcata ctgcaatacc ttcacaactg catcttttct
     8521 aatgatgtca tatacttgtc tcagcttttc tgccgtatca ggtacaggat ttaaattcgg
     8581 catcgcgcat acagtagtga aaccgccacg agcagctgag cgagtcccag cttcgatcgt
     8641 ctccttgtat gtaaatcctg gctctctcaa atgaacatgg acgtccacta aaccaggtgt
     8701 gatcaattgt ccctttgcat caaacacttc atcaaattcg gcttctgaga atcctgtacc
     8761 gattgctttg attcgcccat cttctatcca aatttc
//
LOCUS       DAYYEF010000084         8731 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000084 DAYYEF010000000
VERSION     DAYYEF010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.088"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            2..74
                     /locus_tag="ACHA1B_002587"
     tRNA            2..74
                     /locus_tag="ACHA1B_002587"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            78..150
                     /locus_tag="ACHA1B_002588"
     tRNA            78..150
                     /locus_tag="ACHA1B_002588"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Phe,seq:gaa)
     gene            155..225
                     /locus_tag="ACHA1B_002589"
     tRNA            155..225
                     /locus_tag="ACHA1B_002589"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:187..189,aa:Gly,seq:tcc)
     gene            238..311
                     /locus_tag="ACHA1B_002590"
     tRNA            238..311
                     /locus_tag="ACHA1B_002590"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Ile,seq:gat)
     gene            323..394
                     /locus_tag="ACHA1B_002591"
     tRNA            323..394
                     /locus_tag="ACHA1B_002591"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:356..358,aa:Glu,seq:ttc)
     regulatory      583..662
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="SMK box riboswitch (SAM-III) riboswitch; SAM
                     riboswitches modulate the expression of downstream genes
                     in response to levels of S-adenosylmethionine; SMK box
                     riboswitch shares no known similarity to SAM-I and SAM-II;
                     Derived by automated computational analysis using gene
                     prediction method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            660..1853
                     /gene="metK"
                     /locus_tag="ACHA1B_002592"
     CDS             660..1853
                     /gene="metK"
                     /locus_tag="ACHA1B_002592"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HFM8703310.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            1983..3455
                     /locus_tag="ACHA1B_002593"
     CDS             1983..3455
                     /locus_tag="ACHA1B_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MDR family MFS transporter"
                     /protein_id="HFM8703311.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            3538..4326
                     /locus_tag="ACHA1B_002594"
     CDS             3538..4326
                     /locus_tag="ACHA1B_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HFM8703312.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(4393..5061)
                     /locus_tag="ACHA1B_002595"
     CDS             complement(4393..5061)
                     /locus_tag="ACHA1B_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HFM8703313.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5176..6888
                     /locus_tag="ACHA1B_002596"
     CDS             5176..6888
                     /locus_tag="ACHA1B_002596"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8703314.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            6891..8663
                     /locus_tag="ACHA1B_002597"
     CDS             6891..8663
                     /locus_tag="ACHA1B_002597"
                     /EC_number="7.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8703315.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2622 a         1487 c         1944 g         2678 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgtttggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      121 gtgtcggcag ttcgattctg tcccgcgcca ttatgcgggt gtagtttagt ggtaaaacca
      181 cagccttcca agctgttgtc gcgagttcga ttctcgtcac ccgcttttag tttttatggg
      241 cctatagctc agctggttag agcgcacgcc tgataagcgt gaggtcgatg gttcgagtcc
      301 atttaggccc atttatttta ttggcccgtt ggtcaagcgg ttaagacacc gccctttcac
      361 ggcggtaaca cgggttcgaa tcccgtacgg gtcatggaag atactttttg agtatctttt
      421 tctttttatc tgaaagaatg attttaaaaa gcttagcaga gttatcttta tggatgattg
      481 tgctaagctt ttttggacag ttctaatgta aaatattttt atatttttta agcaaaaaaa
      541 tgaaaaaata cgagcagaaa actgttttat ctgctatact tggttcgttg caagttcccg
      601 aaaggatccg caggacggag atgccttgta accgaattta actaggggga atcattataa
      661 tggtagaaag acacttattt acatcagaat ctgtttctga aggacatcca gataaaattg
      721 ctgaccaaat cagtgatgca atcttggatg caattttaaa acaagatcca acagcacgag
      781 tagcgtgtga aacgtctgta acaactggtc ttgttttagt atttggagaa atatctacga
      841 cggcatatgt agatattcaa aaagtcgtac gggaaacaat aaaagaaatt ggttatacac
      901 gtgcaaaatt cggatttgat ggagatacag cagctgtatt ggttgcgatt gatgaacaat
      961 ctcctgatat tgctcaagga gttgatgaag cacttgagat ccgggatgaa gataaaaaag
     1021 acgtattaga tgagattggt gctggtgacc aaggtttaat gtttgggttt gctgtagatg
     1081 aaacaccaga attgatgcct ttaccaatcg ctttgagtca tcgtctggta cgacgcttgg
     1141 cagatttgcg taaatcaaat gaattaacgt atttacgtcc agatgcaaaa tctcaagtaa
     1201 cggttgaata tgatgatcaa ggacaaccgg aacgcgtaga tacaatcgtt atttcaacac
     1261 agcatgatga tgcagtagat aatgaaacaa ttcgtcatga tgtcatcgaa aaagtagtga
     1321 aggaagttat tccagctgaa ttattagatg atcaaacgaa atattatatc aatccgactg
     1381 gccgatttgt cattggtggt cctcaagggg atgccggatt aacaggaaga aaaatcattg
     1441 ttgatacgta tggcggttat gctcgtcatg gtggcggtgc tttttctggt aaagatgcga
     1501 caaaagttga ccgttctgcc agctatgctg cacgttatat tgctaaaaac attgttgcag
     1561 cagggcttgc tcgcaaagca gaagtacagc tagcttatgc gattggtgtt gctcaacctg
     1621 tttcgatctc aatcaatact ttcggtactg gaacggttcc ggaagaagaa ctgattgctg
     1681 cagtgagaga aaacttcgat cttcggccag caggaatcat cgagatgctt gatttgcgtc
     1741 gtccgattta caaacaaaca gctgcttacg gtcattttgg tcgtacagat gtagatttgc
     1801 cttgggaaca tacggacaaa gtagatgcgt tgaaagcaag tttagcaaaa taagttatat
     1861 tcagctggaa cgatcgccaa gtggtggttg ttccagcttt ttttatggca gttaacctct
     1921 tgaaaaagat agtaattatt tatctatttt tagatcctgt cataatgaaa gggaggaata
     1981 agatgaaaaa agaaacaaat gttactttgg tcacagtgag tattttcatt gcaacgttca
     2041 tgacggctat tgaaggtaca atcgtaacaa ccgctatgcc aacgattgtc ggttcattac
     2101 atggaatgga aatcatgaac tgggtatttt cgatttattt gctgacaaac gctatgctta
     2161 ctccgattta cggaaaactt gcggataaag tgggacggaa accaatcttt atttttggga
     2221 cattattgtt tattatcggt tcgttatttt gcggtttatc tcaaagcatg attgggttga
     2281 ttgctgctcg tgcgattcaa gggatgggtg ctggggcaat gatgccagta gctttgacga
     2341 tcatcggcga tctttattct attgaaaagc gagcaaaagt tttaggtttg aatagttcag
     2401 cctgggggat tgccagtgtt tttggaccgc ttgcgggagg attcatcgtt gaaacgatca
     2461 gctggcactg gatctttttt atcaatgtgc cgatcggaat tctattaatt attttgattt
     2521 ggctatattt aaatgaacca aaaatcatac atgagtctaa accaatggat atttttggta
     2581 gttttagttt gatggccatg cttgtctcat tgctgttagg gttccaatta ttaggagacg
     2641 aaggaatgag tccgcttgtt tctgctttgc tgctaggtag tatcgtaatg ttaggtattt
     2701 ttgtttttgc cgaaaaaaga gctaaagatc ctgtcatcat gatgcattta ttcaaaaatc
     2761 cactatttgt tgtggtcaac ttggctgcag cattggctag tggttttttg atgggaatcg
     2821 atgtttatat ccctatgtgg atgcaaggtg tattagggct gaatgcagca attggtgggc
     2881 tggtattagc accattatca ctagtctgga tggtcggttc tttccttgca agcaagtgga
     2941 tgactcaaat gaaaactcat tgggtcttga gaattggact actaatcgca gctattgggg
     3001 gcgcttggtt gtatcttatg cctttcagaa gtaactattt atggtttttt gctatatcaa
     3061 cggtcatcgg tataggctta ggtgtgacca tgactacctc gactgtcagt gcacaaaata
     3121 gtgtatctcg tgaccagctt ggtgtagcaa cttcttttaa tacgttagtt cgaacaattg
     3181 gtcaaacagt catggtttct atttttggtt tattgataaa tggggtaact aaacgagaac
     3241 ttgcagcagc aaatttaaca aatgatgcag atatcatgaa taaactggtg aatccacaaa
     3301 cggctaaata tattgatgcg gatattttgt taccattaag aaaaattctt tatgatgggt
     3361 tacattccgt ttatctagtt ggcttgttac tcgtgatcat tgctttggtc ttaacgcttt
     3421 tcgttcatga aaaaagtggt aaaataaaac agtagtttcg gttaagatat gtacgtagcc
     3481 gaatcattca aatttaaagt tattcaaaaa taacttctta ctaaggaagg cgaaaatatg
     3541 gcatttattc aagcaaatat ttattcgaat gtgttagaaa tggaagtcaa tctaaatgtg
     3601 atactaccgc aaacaacaaa aaaggtgatt ggcaccagtt cagagcaaga gacaacggat
     3661 atacctgttt tatatttact tcatggaatg ggtggcaatc atagtgtatg ggaaagacgt
     3721 acgtcgattg aacgttatgt agcaaactac ggattagctg tcatcatgcc atctactgat
     3781 cttggctggt acacagatac agtttatgac atgaagtatt ggacattcat tgcagaagag
     3841 ctacctgaga tttgtcatga attattcccg caattaacaa gaaaaagaga aaaaacatat
     3901 gccgctggat tatcgatggg cggatatggc gcgttaaaac taggccttgc aaaatcagaa
     3961 aatttcgcag cagtaatctc tctttcaggc gctgtttctg taggaaatcg aatggatgat
     4021 cttttgatgg ttcgtaaagc atctttttgg gaagggatct ttggaccatt ggatcaaatc
     4081 gaaggttcaa aaaatgatcc gcaatactta ttgaaagaac tagtaaaaag cggaaaacca
     4141 gttccaagat tttatatggc ttgtggggaa tctgattttc tttatcaggc aaatcaggaa
     4201 atggtatctg ctatgcagga acaaggcttg gcggtcacct ttgaacaagg acctggcgat
     4261 cataactgga tcttctggga ccaatggatt caacgtgcat tggcgtggct aatggaagaa
     4321 aaataaaaaa agagtcttaa aaagatagct cctatagaga tcacaaacat agtgatctct
     4381 ataggagctt ttttactgct cgttttctct tcttttattt tgttggcata agccttcaat
     4441 ataggtttgt gcactcgtta gaaagagtgc tttttcattc aattctgcat gggactgcat
     4501 actttcttta aatccctcta attgattttc aactacataa ttacgcataa atagaactgt
     4561 ttctttcaaa aattcatttc cgtccataat tttttgtcga agctgctgtt catgctgctg
     4621 atccattaac tgtccaatca ataaattgtg gagagaggca atggcctgat gactttgggt
     4681 gactgaaaat ccttcacgaa caagtaattg gatcatttgc tccaaatgtt ctaatcgact
     4741 cggaaaagcg ggcacagtat tgatttctaa ttctgcccca caagggaaac gtgtataaag
     4801 gtcatagtaa ttttccatat actgcagcaa ctgttcattc caaggcaaag ttggatctgg
     4861 aagcgctaat tcttcttcca ttgtttcagc cattttttgc aagagctgtt gtttgttttt
     4921 gaaataccaa tataaagcag gtgcttgaac atgaattctg tttgcgatgt ttcgcatgga
     4981 aagctgcgaa agagcttgtg tttcagccag gatatcaaag gcggcctgaa tgatgattgc
     5041 ttgagaaagc tttatttcca ttttatcaac ctcgtgtatt gcattatctt tttaaacatg
     5101 gtaaattgtt agtcggtcta attttacagt gttaaattag tcctgtcaat ttaaacaaag
     5161 gggtgtaatc aacgaatgaa attaatctta cgacatgcga aaaaatataa agtagctgtt
     5221 tttatttcct tgctgtccgt agcagtcatg gttgcagcag cattatggca acctaagtta
     5281 ctacagcaag tattggaagc tattattaca gaagataatg atgaaatgaa aacaattggt
     5341 atttacctga tcagtctggc tttgctagga ttagccgcag gtgtaacgaa cacgattttc
     5401 tctgcaaaag tagctcaagg cgtaagtgca gatatccgag aagaagcatt tcgaaagatc
     5461 cagacatttt catttggaaa tatcgaacag ttctctgctg gaaatcttgt tgttcgtcta
     5521 acaaatgata tcacgcaaat ccaaaattta gtgatgattt ctttgcaatc actttttcga
     5581 attccattct tatttattgg tgccttcatt ttagctatga tcacgatgcc gcaattatgg
     5641 tggatcatcg tagcgcttat cgttacggta tttctgatta cggcactttc atttacaagg
     5701 atgggcaagc acttcatgat cattcaaaaa ctgattgatc gtgtgaatag cattgcaaaa
     5761 gaaaacttac tagggattcg tgtagtgaaa tcttttgtac aagaagaaaa ccaattgaag
     5821 tcattcagca aagtaagtga ggacttaaca aaacacaaca tcatagtcgg tacattattt
     5881 tctgtgatga tcccgtcctt catgctggct gccaatttgg ctgtggttgg ggcgatcttt
     5941 tttgtgagcg atcttgttaa agatgatcct acgttaattg gtggaattgc ttcattcatg
     6001 aactacttga tgcagattat gatggcaatc attattggcg gaatgatgat gatgatgact
     6061 tcaagagcag ccgtatcgct gaagcggatt gcggaaattt tagatgctga accagatctt
     6121 acttatttag acgttccaga acaagagttg acgggttctg tcacttttga ccatgtttct
     6181 tttcgttatc ctggtgagga tacagatacg cttaaagata tcagcttttc tatcaaacct
     6241 ggagaaatgg ttggtatcgt cggggcgact ggtgccggga agtcaacact agcacaattg
     6301 atccctcgtc tatttgatcc gacagaaggc aaagttgaag taggtggtgt agatcttcgt
     6361 caagtaaatg aaaagagttt aagacaaacg gtttcctttg ttttgcaaaa agcaatttta
     6421 ttctcaggaa cgattgctca aaacttgcgc caagggaaaa agaatgcaac agaaaaagag
     6481 atggaacatg cttcttctat tgctcaagca aaagaattca tcgaaaagtt atctgatcgt
     6541 tacgaagcac caatagaaga acgtagcagt aacttttctg gtggtcaaaa gcaacgttta
     6601 tccattactc gtggcgttat cggtaatcca aagatcttga tcctagatga cagtacgagt
     6661 gcactggatg ctcgctctga aaagctggtc cgagaagcac tcgatcgaga tttgaaggga
     6721 acaacgacga ttgtcatcgc acaaaaaatt gcttctgttg tcaaagcaga ccgcatctta
     6781 gtattggatg aaggcagatt agtcggcgaa ggaacccatg aggaattggt agctggaaac
     6841 cgtgtctatc aggaaatctt tgaaactcaa aaaggaacgg aggagtaagt atgactgatc
     6901 taataaaagc aagtaaattt ttctatcact atttgaagcg gtacaaactc tcctttttct
     6961 ttatctttat cacagtgatc attgctacct atctacaagt aaaggcacct caatacatcg
     7021 gggaagcttt tcaagaatta gctaattacg taggaggctt gatgcaaggc gtagacgata
     7081 aaagcaaatt tgtttctgta atatggaaac tcttgctgtt ttatgtacta gctagtgcag
     7141 ccaactttat ctatagtatt ttgttcacac aagtagtagg gaagtcaacg aaccgaatgc
     7201 gtatcggtct attcaacaaa ttggaaaaat tgacgatccg tttctttgat tctcatcaag
     7261 acggtgaaat tttaagtcgt tttaccagtg acttagataa tattcaaaat agtttgaacc
     7321 aagctttgct tcaagtcatc acgaatgctg ttttacttgt cgggatcttg atcatgatgt
     7381 tccgccaaaa tgtagagtta gcttgggcta caattgcttc cactccagta gccgttttga
     7441 tagctgtctt gattatccgc aaagcacgga aatatgtgga tcttcagcaa gatgaagtgg
     7501 ggaaactaaa tggttatatg gatgaaaaaa tcagcggaca acgtgtcatc atcacaaatg
     7561 gcttacaaga agaaacgatt gaaggattct tagagcataa tcaaagtgtt cgcgaagcaa
     7621 ccttcaaagg acaagcttat tctggtctac tatttccgat gatgcaagga atgtcactgg
     7681 tcaatacagc gatagttatc tttttcggcg gctggttagc attaaatggt gatttggaac
     7741 gttcggtggc attaggctta gttgtgacat tcgtccagta ttcacaacaa tattaccaac
     7801 cactgatgca gatttcatct ggatacagca tgatccaatt agcgattaca ggggcaagac
     7861 gattgaatga aatatttgat gaaaaagatg aagtcaaacc agaaaacggt aaagcatttg
     7921 atggtgttga aaaaggtctt gcgttgcagc acgtagattt tggttattct ccagaaaaac
     7981 tagtcttgaa agatgtctcg atcaatgtgg acaaaggaga aatggttgct cttgttggtc
     8041 caacaggatc ggggaaaacg acgatcatga atctgctaaa ccgtttttac gatgtcaatg
     8101 atggttcagt agtcatcgat ggaatagata tccgagatta tgatcttgat gcattacgta
     8161 gacatgtagg aatcgttttg caagaatctg tattgttctc cggaacgatc aaagacaata
     8221 tcacattcgg caaaccggac gcttcagatg aagaagtcat caatgcagca aaacaagcga
     8281 atattcatga cttcatcatg acgttagaaa aaggttatga tacagagata tccgaagaaa
     8341 ataacttatt cagtacaggt caaaagcagt tgatcagtat tgctcgaacg atcatcacaa
     8401 atccatcttt attgattttg gatgaagcaa caagtaatgt agacacggta acagaagcaa
     8461 ggatccaaaa agcaatggat gaagcaatca aaggaagaac cagctttgtg attgctcacc
     8521 ggctgaaaac aatcttgaat gcagatagaa tcgttgtctt gcgtgatggg gaagtcattg
     8581 aagaaggcag tcatcatgag ttattagcag aaaatggatt ttatgcggaa ctttatcata
     8641 atcaatttgt atttgaaagt taaattaaaa gaacctcgtt ataacggggt tctttttata
     8701 tattttatgt tgtttgtttt tataaggggc a
//
LOCUS       DAYYEF010000085         8593 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000085 DAYYEF010000000
VERSION     DAYYEF010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.089"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(52..1518)
                     /locus_tag="ACHA1B_002598"
     CDS             complement(52..1518)
                     /locus_tag="ACHA1B_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HFM8703316.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1905..2501
                     /locus_tag="ACHA1B_002599"
     CDS             1905..2501
                     /locus_tag="ACHA1B_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFM8703317.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(2559..3041)
                     /locus_tag="ACHA1B_002600"
     CDS             complement(2559..3041)
                     /locus_tag="ACHA1B_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703318.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3147..3344)
                     /locus_tag="ACHA1B_002601"
     CDS             complement(3147..3344)
                     /locus_tag="ACHA1B_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703319.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3639..4397
                     /locus_tag="ACHA1B_002602"
     CDS             3639..4397
                     /locus_tag="ACHA1B_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HFM8703320.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4457..4885
                     /locus_tag="ACHA1B_002603"
     CDS             4457..4885
                     /locus_tag="ACHA1B_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703321.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4931..5003
                     /locus_tag="ACHA1B_002604"
     tRNA            4931..5003
                     /locus_tag="ACHA1B_002604"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4964..4966,aa:Gln,seq:ctg)
     gene            complement(5153..5524)
                     /locus_tag="ACHA1B_002605"
     CDS             complement(5153..5524)
                     /locus_tag="ACHA1B_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HFM8703322.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5739..5924
                     /locus_tag="ACHA1B_002606"
     CDS             5739..5924
                     /locus_tag="ACHA1B_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703323.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6007..6195)
                     /locus_tag="ACHA1B_002607"
     CDS             complement(6007..6195)
                     /locus_tag="ACHA1B_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703324.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6219..6482)
                     /locus_tag="ACHA1B_002608"
     CDS             complement(6219..6482)
                     /locus_tag="ACHA1B_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703325.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6640..6897
                     /locus_tag="ACHA1B_002609"
     CDS             6640..6897
                     /locus_tag="ACHA1B_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HFM8703326.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6968..7159)
                     /locus_tag="ACHA1B_002610"
     CDS             complement(6968..7159)
                     /locus_tag="ACHA1B_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703327.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7300..7620)
                     /locus_tag="ACHA1B_002611"
     CDS             complement(7300..7620)
                     /locus_tag="ACHA1B_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703328.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7643..8077)
                     /locus_tag="ACHA1B_002612"
     CDS             complement(7643..8077)
                     /locus_tag="ACHA1B_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HFM8703329.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8412..>8593
                     /locus_tag="ACHA1B_002613"
     CDS             8412..>8593
                     /locus_tag="ACHA1B_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HFM8703330.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT         2725 a         1695 c         1361 g         2812 t
ORIGIN      
        1 aaaaaacagg aactgctgca aataagcaat tcctgttttt atgttcattg attaatgaat
       61 agagcccatt agttttttga ttggttcttt cacagtaaat agcaagatac caccgacgat
      121 tgctactgca ccgataatac cgaagtaagc agattctgtt cccggtgtgt agaagcgtgc
      181 aatttgtgca ttgattgctt gtgaagaagc atcagctaag aaccaaatag cgattgtttg
      241 tgattcaaat gctcgtggtg ctaattttgt tgtcacagac aaaccaactg gtgaaagaca
      301 caattcagca ataaccacga tgaagaaact tcccaacaac cacaatggac ttacttttcc
      361 acttgtacca taaagcatac ccggcaacat caatagcaag tacgataatc ctgcaaataa
      421 aagtccaaga gagaatttca ctactgtaga tggttgacgt tcaccaagtt tcgtccacat
      481 cgttacgaat actggtgtca gaataaagat gaaaattgga ttcaatgatt gataccagct
      541 tgcttggatc gttacaccaa atagcgtaga ttgtgtacgt tcactagcaa ataaagctaa
      601 gatagatgaa ccttgttctt gtaatgacca gaaaatgatt gctgcaagga ataatgggat
      661 ataagcccat actcttggtt tttcttcagc agttacatct tttgaagtca gcattttgat
      721 aaagtaatac aacggtaaga taatccccaa tacactgatt gtattgacaa aaaagtcaat
      781 tgtcagatga ccagttagtt gtgccccgcc gaatactgca gcgataacaa caagtgcgat
      841 gatcaagtta cggatgaatc ctttacgttc ttcagttgtc aaaggattcg gcggtgttgt
      901 acccactccg tctaatgtct tgcgtccttg gatgatgtat tgtaataatc caaagaacat
      961 cccaatagca gctaaagaga accctaaatg atagttatat tcttgaccga ttgtaccaac
     1021 gattagtggt gctaataatg cccctaagtt gacacccatg taaaaaatcg aaaatcctgc
     1081 atctcttcgc aagtcagtct ttgaataaag atgtccgacc atgccagaaa catttggttt
     1141 caaaaaggcg gttccgataa taatcaatgc catcgaaaca aacaatgtac ttacaccaaa
     1201 tggtaaagcc aagacgatgt ggccaagcat aatgaaaact ccaccgaaga atacagtgcg
     1261 ttttgctcct aacactcggt cagataccca tccgccgacg atactagaca tgtagatcaa
     1321 agatccgtag atcgacatga tagctaatgc tgttgctcgt ggtaatccaa gtcccccgtt
     1381 ggcaactgta tcgtacatat aatagataag taatgcacgc ataccgtaat aactaaatcg
     1441 ttcccacatc tcagtgaaga acaaagttga caatcccttc ggctgcccga agaagccctt
     1501 gtcttgctgt ttttccataa tctatacccc aattctttaa attttcagaa aatattatac
     1561 atctttaccg aaaaatttaa ctaaaaaact tatttaagaa atataaacta attttctata
     1621 aaagcaagta atttttaatg gcaatatcat aaaaaaaaga agatagagat ttaataatta
     1681 tatatcagct gtttttttca aataagcaaa aattcctaaa acacaacaat gaaagcgata
     1741 actaagaaaa tccttacata acgatttttc ttattaaaat tgttttttga acttcgctta
     1801 ttttttgtga gcatatctgt ttacttactt tttgtaaggt gctatacttc atttcgtaat
     1861 caattaaaaa aatgcaaaac gcaaatcaaa ggagaaattt tattatgaca acttttactg
     1921 acactttgaa aaaccgccgt tcaatctatc atctaggacg taatgtttca ctttctaatg
     1981 aagaattaac aactttgatc aaagaagcaa ttaaagaaag cccaactgct ttcaatgctc
     2041 aatcaacacg cgcagttatc cttttcggag atgcacatga aaaactttgg gaaatcactg
     2101 aagaagcact tcgcccattg actccagcag aagctttccc aaatacacaa aacaaattag
     2161 ctggtttcaa aaatggttat ggtacagtat tattcttcaa agatactgac gtggtaaaag
     2221 gtctacaaga acaatttgaa ttatatgcag acaacttccc agattggtca gaacaatcaa
     2281 acggaatcgc aacagctaat acttgggtag cattagttga taaaggattg ggcgcaaact
     2341 tgcaacatta caacccagtt attgacgaag cagttgcaaa agaatggaat atcccttcaa
     2401 actggaaact acgttcgcaa ttagtattcg gttcaccaga aacaccggct gaggaaaaag
     2461 aatacatgaa cgatgccgat cgcttccgcg tatttggata attttatttg aaataaaaaa
     2521 cagaggttgt gacaaacatc ttgtcgcaac ctctgttttt attctggatc aatcataata
     2581 tcaatctctg cctcatcgtt taagcgttgg gacaaaaatg gaactaattc ttctaatgat
     2641 gcagaaaatt tcagcatcgg tcctcgccat ccgtttcgga aaaaattcat ttttacgatt
     2701 ttagaacctt ttggctgata taatacaatt ttattgatct cagaaaaagg aacacctttt
     2761 ttgtcaaagc tattcaaaac aagtccttct tctgtgattc ctctactgtc caacaaaaaa
     2821 ctaataaaaa tcattgctga caagatccct tttgccaatt catctgctgt aggatgactg
     2881 atgagtgtat accaaatgac tagtgacact aagaagggta tcaccaagta gacccatcga
     2941 tttcgcacag tccgataaat aatttctttt cgaaccagcc aaagaaataa aaacatcaca
     3001 acaacgaata aaaacaatag aaccgtaaag aatgttacca tgacaactcg cctcgctttt
     3061 tcttctccag aaaataggaa aagaatactg atttaccttc tcaaagaaat tggacttgca
     3121 gcacgccgca cgtccaattg ttttctttat tcaaatgtat catattttgc aacaaccatg
     3181 cttgcttttt catctaataa ttcttggtcc tctgcagcac attgggcaac tttgaccacg
     3241 gcgcagtttg tcatttttga tacaacttca ccaatgaccg tttttgtaaa accaattggt
     3301 ttgcatgcat attgttctcc taaattaatc atttcttccg tcatcaaaat cctcctaaac
     3361 tgctggaact tttctccaca ttaccactgc tatttctttg gagatttaac tcattgattt
     3421 ttatttacag ttaaaaatca accttacagg cattatagcg tactgttttc gttttcacaa
     3481 ttaaaacagc tgttgtattt agaagaattt ttttcaaaaa attaaaacat attccttaaa
     3541 aactaattat ttcctacata ttaaaatata atacttccat ttccaataaa aatacattta
     3601 taataggaaa gataaacagc tgaaaaggga gatttcaaat gaagaaaaaa acgttcaaaa
     3661 aactattgtt tctagggggc acagctgctc ttttattaag cggtacaagt tattacctac
     3721 atatccattc tccagaacat acaatgaaca ctgcacaaaa aagttcaaca caaaaaacga
     3781 aaaagacaaa agagaaagca gaagttttac tagatgttcc attagagagc cagtttgatt
     3841 ctccttcttt agaaaatggc tgtgaagtca cttcgctttc tatgctttta tctttttatg
     3901 gttatgaaac aactaaaaac cagttagctg agcaattgga ttacgtccct gttttcaatg
     3961 cagatgggac tcatggcgat cctaatgaag gatttgttgg tgatatcagt ggcggagact
     4021 gggctatggt cgtctatgtt cccccagttg cctcccttgc tcagcaaatc gtccaaacgg
     4081 attatcacac ttttccaaaa accgatgctc aactcgatga tatcaaaaaa gcactatcta
     4141 aaggaaatcc tgtctggact tctgtgacta tcaattttga agtcccagat gaaactgatt
     4201 ttatgacttg gaccacaaat aatggagaag taagagtcac tcctcttgtt catgcttgtg
     4261 tagtcactgg atatgacaaa gaaaatattt atgtcaacga tccctatggt gtaaaaaatc
     4321 gagcagtacc gatcaacgat ttttcggcga ttttcactgc aatgggtgga cagatgctaa
     4381 ctttggagaa aagctagtaa ttcaaacaaa aatcccttat actcaagata ccaaaccttt
     4441 gaagggagcg tagataatgg aaaaattcac acataaaaaa atggatccaa atgaaattcc
     4501 gattattttt gtccgtgact gcaagggaaa tgttcaaggt aaagtctcta ttaatgagtg
     4561 gaacgagcgt cgcagacctg ctaccctcaa tgaactggaa atcaaattgt atcgtcaatc
     4621 tcttgtttat tacgcagatc aagagtacga gaaagccacc gatttattga aatttctaat
     4681 tgctcgaaca gagtatactc gctttgaata tattgaacgt ttagcaaaca tctatcatat
     4741 tatgaatgaa cctgtcaaag aatatcagtt attggacacc gtcttgtcag tagcagaact
     4801 gattgccctt cctgctggat tagaaaagaa actagtacgc cgccttttac gagtaaagca
     4861 acaactatcc gatcaagaaa aataacttgc gtttttttag gaaagtgcta tgattatttt
     4921 gttgaataaa tgggatgtag ccaaactggt aaggcacttg actctgaatc aagcaattgt
     4981 aggttcgaac cctgccatcc caatttgatg tgcttgctga aaaaatgaac cccctgtaaa
     5041 agaacaatct ttttgcaggg ggattattgt attattttta ctacttgtat ttagtttaca
     5101 taattaaatt atgaataata aaatcgggcg tattcttaat acaaaaactg atttacccaa
     5161 taattgctaa tgctttctcc ggaacttttt ctctaggaac ttcctcatac gtttctatgt
     5221 gtgctccttt attgctaatt ttcaaataat gattttcttt taacacagaa agaccattaa
     5281 attcaaccgt tcgttctttc ccattggcat cagcagcttt ctgcacatac cttgctgtac
     5341 catattcatt tacttcctct ggtttttgtg tctttacata gacctctcct ttttcaacta
     5401 atggatttag ctgatcaagt ataccaggga tttctccata acttccttca gtataatatt
     5461 tcagtccaaa tagcaaaata ccactaatcg ccgccagtcc aatcaaatat ttaatcactt
     5521 tcatctttct acctccttgt tatatattca gtatatgggt cagttaaaga aattccatcc
     5581 gtcccaagtt ggagattttt ctcctacttt agaagcgaga atcgagtgtt tttttagtaa
     5641 aaatgatcgt tatttgatat tattgacgtg tggataaatc agtttttctc gttttgtcca
     5701 tgtaaaaaat catgttgata gcaaaggatg tgttcaaaat gaatcaagaa gaattatttc
     5761 aaaaagtcaa ggaaatgatt aagaacggca atttcgatgg cgcaaaacga tttatcgaag
     5821 aacataaaga acaattagga ccttataaag agaaagccca aaatctttta aaagatgtaa
     5881 atatcgacag tgtcaaaaac aaatttaaaa atctattcaa ataagtaaaa ctttcacttt
     5941 tgtaaaatca aaggaggaca atgctgctgc atcgtcctcc tttggttctt ttctgaatac
     6001 ttcatactaa aataaacgtg tcggatcgta atgataagtc acattgccgt tcagtgaggc
     6061 ttttcccacc acatatttac gattctccaa cttcagccac gcttctcgaa aagccattaa
     6121 ttcttctctt tttacatcaa tcttttcgat ttttccatcg atcaaatctt gaataagttg
     6181 ttcatatgga ttcatttttt tcctccatct gctgtcaatc aataagttgt aaaaataggt
     6241 tcatatgctt ttttggtatc tagatcttct ctgactttga ctgtcgtata aataattttt
     6301 tctactggga tactataata acttccttca ccattattga atcggtgaac gtctttcttt
     6361 gctaaaatac catttatttt attcgtcagt acacgttgtt cgacactgtt acttacaaca
     6421 tagtaaatca cccgaatatt attgatcaaa tgcaaatcga tttctaacac tacatgatcc
     6481 atgaaaatcc cactccttct ttcactttga ttatagcaag tttctcctct aatttcaaaa
     6541 tcgatacaga ttttaccgga taaatccaca aaactgcttg cgccatttcg cacaaagtgt
     6601 tattttgtat catggacttt atttatcgga ggcaatagta tgatcgcgat cggtcaattt
     6661 gttttttata ttcctttttt tattatgata agcattcttt tctattacat aaaatggaca
     6721 aaaaagaagt tttcagtttt actggcctct ttacctgctg tatattttac ttatcaaatt
     6781 ttttctttta ggcattggga aacaacgtct gtattaataa cacacatcat cgaattgacg
     6841 ctttcagtaa tttttcttat tatttggatc tattttttat ataagaatca gaattgaatc
     6901 cctcgcatgt ttaaaaagaa aacgattaaa gatgcagcaa atttctgccg atctttaatc
     6961 gttttttcta ttctgttata ccaaaaaaat gtttgaatcg gtgaaggatc gttccttgtt
     7021 ttaattctat aaattcttgt gcgatcgggt acttttcttc caaattttct ttgttctttt
     7081 cgatcaggct tttcgcttct tcatattttt tatctgcaca tagtgctttt acttcctgta
     7141 atacttttcc tgcttccatt tgcctcaccc tcttgccatt ttattgcttt aagttttatt
     7201 taagttatac gcattattct agtttcatcc caaataacct tttttcattt ttactcctcg
     7261 aactaatcag ttttctaaag gctgattggt tcgtcttttt tatttttcct ccatttcatt
     7321 ctgctcttct gttaatttat ctaatgcttt gattgatgct gcggctcttg cataatcata
     7381 gctgtataat tccataaatt tatcaggcag aacaaaccac gctggatgat aaccgttagc
     7441 tgtgacaggg aatcctttat cttgttggtt atctccatcc catctcagag caacaccttt
     7501 ttttcctttc cactttacta aagcgatcga gtatcccttc tttgtttgtg tgccgtcttc
     7561 aataattgct aaaatttcta ttttttcttt tggcgcacgg acttcttgag gacgaaccat
     7621 tttctattcc tcccttatct cattacttca cgaccaacac actgcaaggg gcatgtgata
     7681 cgacataaga agcggtcgat ccaactaatg cttgttgtat agcacctttt cctgtcgctc
     7741 ccataacgat caaatcaata ttttcttgtc cagggatgac attggcaatc aaatttcttg
     7801 gatctccagt ttcaactatt gcgtggatct cagcaatgcc gtactctttg gcatcattga
     7861 tttttttcag catggctact tctgttcttt gtttttcatc tgcatagatt tttgaaaagg
     7921 cataggcact atgggtcagc tcaactttgt tgatgattga cacgataaat aagtgggctt
     7981 cattgtcctt tgctaagtca agggcttcag cgaacgcttt gatcgattgt cttgatccgt
     8041 caactgctac catgatgttc tggtatcttt tactcattgg aaccgcctcc tttttctttt
     8101 attgtaacat ctcaagcaaa aatacaaaaa atatacgcaa tatgtaaata aaatgatgaa
     8161 caaaagcaat ttctttcaag ttatttatac atttcttttc tcatcagaac acctgttcta
     8221 atcccattat ttctgcatta tgtgaaattc ctcatcattt ttcacatcga gcgaacatca
     8281 ttctgttaca aaaaacgtgg atttgtcata aattgtcatg cttcttttac ctatgaaata
     8341 ttttcacgtg ttaaagtatt cctcgttgaa cacaacaaat aaaacttttt aacgaataaa
     8401 ggagattttt catgacatca cttaaaactt tactttttgg aacaactttg gctgccggcg
     8461 ctgcattctt catgggaacg actgctcatg cggacgaagc ttataccgtt caatcaggtg
     8521 atactctatc aacgatttct caaaaatacg ttggtgataa ctccttgatc aatgccattg
     8581 cagaatcaaa ttc
//
LOCUS       DAYYEF010000086         8228 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000086 DAYYEF010000000
VERSION     DAYYEF010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.090"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="ACHA1B_002614"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="ACHA1B_002614"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HFM8703331.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="ACHA1B_002615"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="ACHA1B_002615"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0003919 - FMN adenylyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006747 - FAD biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HFM8703332.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="ACHA1B_002616"
     CDS             2591..3376
                     /locus_tag="ACHA1B_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFM8703333.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="ACHA1B_002617"
     CDS             3389..4240
                     /locus_tag="ACHA1B_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015144 - carbohydrate transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0034219 - carbohydrate transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HFM8703334.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="ACHA1B_002618"
     CDS             complement(4364..4816)
                     /locus_tag="ACHA1B_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703335.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="ACHA1B_002619"
     CDS             complement(5281..5649)
                     /locus_tag="ACHA1B_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HFM8703336.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="ACHA1B_002620"
     CDS             5799..6281
                     /locus_tag="ACHA1B_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HFM8703337.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="ACHA1B_002621"
     CDS             6318..7328
                     /locus_tag="ACHA1B_002621"
                     /EC_number="3.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="S66 peptidase family protein"
                     /protein_id="HFM8703338.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="ACHA1B_002622"
     CDS             complement(7443..8156)
                     /locus_tag="ACHA1B_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703339.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1667 g         2440 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtc
//
LOCUS       DAYYEF010000087         7983 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000087 DAYYEF010000000
VERSION     DAYYEF010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7983
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.091"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            29..1666
                     /locus_tag="ACHA1B_002623"
     CDS             29..1666
                     /locus_tag="ACHA1B_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703340.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(1811..2551)
                     /gene="truA"
                     /locus_tag="ACHA1B_002624"
     CDS             complement(1811..2551)
                     /gene="truA"
                     /locus_tag="ACHA1B_002624"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003723 - RNA binding [Evidence IEA];
                     GO_function: GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0001522 - pseudouridine synthesis [Evidence
                     IEA];
                     GO_process: GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HFM8703341.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(2742..3377)
                     /locus_tag="ACHA1B_002625"
     CDS             complement(2742..3377)
                     /locus_tag="ACHA1B_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HFM8703342.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3524..4744)
                     /gene="sstT"
                     /locus_tag="ACHA1B_002626"
     CDS             complement(3524..4744)
                     /gene="sstT"
                     /locus_tag="ACHA1B_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015293 - symporter activity [Evidence
                     IEA];
                     GO_process: GO:0015826 - threonine transport [Evidence
                     IEA];
                     GO_process: GO:0032329 - serine transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HFM8703343.1"
                     /translation="MSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSCLKAIAPI
                     LVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPITLQETVSE
                     KAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSESTKELVDQI
                     SIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLFVALVVYP
                     FLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKESYSISIP
                     LGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGVAGGSLLL
                     IPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELGARKRSGE
                     KIKLKDCLDGLSER"
     gene            5312..>7983
                     /locus_tag="ACHA1B_002627"
     CDS             5312..>7983
                     /locus_tag="ACHA1B_002627"
                     /inference="COORDINATES: protein motif:HMM:NF013080.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HFM8703344.1"
                     /translation="MNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFICY
                     LLAVSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLFVHKSYFLVAAF
                     FYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFFFLLLLISNRFW
                     YALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVSPVLLIVGGLIL
                     LLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHKNSPSFLLFNLF
                     KVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMKKYNTKADEINQ
                     TRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTGGLMLSVGYGGG
                     TANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIAIHPFTAALYRR
                     KQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQSNTETSQFIQL
                     STMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAVKKFIQEIDKID
                     KPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAATLNKEVVAPNNF
                     GAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVFVTEDSQIIQEK
                     NLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
BASE COUNT         2614 a         1493 c         1238 g         2638 t
ORIGIN      
        1 ttttattact tttaaatagg agaaaaaaat gaaaaaaaac aaaaaccaaa taatagatat
       61 catttttatg ttatttctaa gttttgctta cgtcatccct ctattcatgt ctatgggaat
      121 ctatcatagt gtcaatcagg atacttactt tcatttatct cgaatcatag gactagataa
      181 tgtatggagt tctccagtaa acttcaataa cttcgatcat catggaacaa tgatgaatat
      241 tttttatcca tggcttactc tttatccagc ttttttattt tataaaatga tgggaaatct
      301 tgttttaagt tataatatct actatttttt tatcactttt ttaacaatgg tcgtttctta
      361 tttttctatg aaacaaataa aaaacaatcg ttatatttcg ctgttatttt cgattattta
      421 tacattttcc gcctatcgtg ccattgacat attccatcgt gcttcattgg gagaagctgt
      481 cgctttaaca tttttgcctt tgatactaat ggggtgttac gaaatttata ttagagatta
      541 ccaaaaatgg tactggttgt ctattggcat gacgctagta gtgtatactc atttactttc
      601 tgtcgctatg gtttctgtat ttattggagg aacgttgttt ctttcttttt atttttggga
      661 ccaaaaaatc gctagactct taagtctttt aaaagctacc gtcctcacct tttttttaag
      721 tgcgggattc ttaattcctt ttattcaaca atctagagca caagaattga aagtcccact
      781 gggaaaagaa ttaagtggta tggctcctag tgatatgctg acacacattt taaataataa
      841 ctataacaac tatactattg gattattctt atttctcgga ttgattggtg cttttatttt
      901 tataaaaaaa ttaactgctg atgatttatt tattttcttt cttggtgtat ttgttctttt
      961 ttgttcaacc aatttatttc cttggcaact ttttaaccat acaccagtta agagtctaca
     1021 atttgtctgg cggttaaatg gtttttcttc tttatttata gcctatacga tgagtatagt
     1081 gatctattat attttttcta ctaaaaataa ttcatggaaa ataatggtct ttacgtttct
     1141 tgcactaata ttgcatctct caggagtaag caattctatc catgctaaca aagattcatt
     1201 aacacttata gcacctgaag acgctgttgc tatagctgaa aattacaatc atactgatta
     1261 tgcaaacaaa gagtcaatct atcatcctga tatgattaat aatgatcaat atttactagg
     1321 taaccaggaa ataaatccaa caactcattt tatgagtaac aaacttacaa ttgaattaga
     1381 taattcgaat aataaaaata ctgtcttgac gacacctatt tatcgttata aagggcaagt
     1441 ggcttctatt aatggcaaac tagtacaaac aaaattatct aagtttggca caactgaatt
     1501 aactattcct ccaggtataa ataaagtcgt tattacttat cagtacacaa aactagcaat
     1561 tgcttcaaga tatttatcta tcgttacttt gattttattt ttactttatc gatttacttt
     1621 ttctaaacaa aaacaaccga gaagagaagt acaacattct cactagattt ttatttaaga
     1681 aagacttttt agctgtacac ataaacaggc taaaaagtct ttttttatat ttctttaatt
     1741 tgcttcatac attatttaac atcgatattt atactgtgaa acatgcgttt catccattat
     1801 caaagtattt ttatcgataa taaacttcat ccaaaaacag accttgtgca gggacggttt
     1861 ctcctgcatg ttgccgcact ttgctttcaa atatttcatc gattgtttct atcggcatgg
     1921 cacctgtgcc gatttctagt aatgtcccca tgataatccg caccatttta tataagaatc
     1981 cgtctccgac aaaagtaaaa tgaagcattt ctccctttcg ttcgatagat aattcatcaa
     2041 tcgtacgcac tgtggatttt tttgattttt tcaatgcaga aaaaccaatg aaatcatgtg
     2101 tacccactaa tttttcgcaa gctgcattca gcttgtccat atccaactct tgagggaaat
     2161 aaaagctgtg gtttcgctca aatgctgaag gaatcacgtt gttccaaaca taatagctgt
     2221 attttttgcc caccgcatta tatcttgaat ggaagcgctc aggcatttct tcgattcttt
     2281 tgatgacaat atcccgcgga aggtaacgat tcataaagtc gatcatttct gccagtccaa
     2341 tttctgtgtt tgttttaaaa tttgctactt gtcctcgcgc atgggtgcca gcatctgttc
     2401 ttcctgatcc aataatttct atctcttcat ttgtcatctg atgcaatact ttttcgattt
     2461 ttccttgaat ggttttatcg tcatctccaa gtctttgcca tcctgaatat ctttttccgt
     2521 catattcgat tgtcaacttg atgtttctca tattttagtg gctcctctgt cttccatttg
     2581 gtcttctctc taccttttta agattgtagc acaaaatata gctcctttct tctctaaaac
     2641 agaagctata caagaaaact gtggaaatat atatttcaga aaaacaaaaa acagccaccg
     2701 gatgaagtat ccgctgactg ttcaatttga cggctcaagt tttactgttt gagatgcaag
     2761 atactcaacc aggcaatggg cacataatta aagaaaaaac tgattctttg gcaaaaacct
     2821 attttattca gtaatggcca agaatttata gaaggaattc ttgccagtcc ataaatcgcc
     2881 gcaaaaagca aactgatcac agacagtcca aggtataagt ggcttacgtc catttgccca
     2941 ttttttcgat agatcaagaa aagaagaact ggaaacaata aaaaaccact gtaacctaaa
     3001 cctgatccga tattatggac ccatgtcgag acattccacg aagattcatg ggtattgata
     3061 ctgaacaaac ctgtaaagat acaatcacct ataccataga acgcgatggc tgctgtaact
     3121 agggtagcta acacacgaga tgtacttaca aatgcagcat acaatgcagg caatgacagg
     3181 atgaaaaaga tccctgaaac cacagaccaa ataagaaacg cttttcttac aggactggaa
     3241 acctctccaa atacactgat cacgctcttc atttgatcta attcaggata atacaatcct
     3301 aatacgtacg gagtcaaaaa atcactcagc acgcctaata ataaaaagaa aaaaccaaat
     3361 ttacgtaaaa aatccatgat acgcctccaa taacaattac ctatgctttt aattgttatt
     3421 ataagcgact ttatcttgat ttaacagaaa cctctattta cacgaacatc tatataactc
     3481 attaaaaact cgaatcattt taaaaatact aaatatctaa cgttcaacgt tcacttaatc
     3541 catctaaaca atctttcaat ttgatttttt ccccacttct tttacgcgcg cctagctctc
     3601 ctattgcagt aaacaacaga tcacttgacg aatttaaggc agtttccatt gaatcctgga
     3661 taacaccgat aataaatcca ataccgacga tttgcatcgc gacatcatta gagataccaa
     3721 acaaactaca tgctaatgga atcaataaca gtgaaccgcc cgcaacacct gaagctccac
     3781 aagcagctaa agcagacaaa atacataaaa ggactttcaa aacaaaaggt gcttcaatcc
     3841 ctaaagaatg tacagcagtc aacgtcatca aggaaatggt aatcgcggca ccgcccatat
     3901 tgatcgtagc acctaacggg atcgatatgg aataagactc ttttgtcaat ttcaatcttt
     3961 cagccaacat catgtttatc gggatatttg cggcagaact tcgggtaaag aaagcgggaa
     4021 gtgcgctttc tttcaaacaa aagaaaatca atggataggg attttcttta ataaacaaaa
     4081 acgtgaggaa tgggtacaca actaatgcga caaacagcat cgtaccgatc aaaacaagta
     4141 aaagctgcag atactctgcc aatccagcta ttccagtcgt agcaattgat tgataaacca
     4201 atcctaaaat ccctatcgga gcaaatgcaa taatcacttg tacgacttgt gacaacgcta
     4261 tagatatctg atccaccaac tcttttgtcg attctgaacg tgctcgaaaa gctagtccca
     4321 acaatacagc ccagaataag acgccaaggt aattcgcatc aataagagat tgaacaggat
     4381 tttgtgtgac attcgtcaac atagtagata aaacactttc caaactttgc ggtgcttttt
     4441 cagatactgt ttcttgtaaa gtaataggaa cagtaaaaat tgaacttaca ataactgcta
     4501 caagtgcaga aagcaatgtt cccactaaat ataagatcaa aataggcttc acgaatgtct
     4561 tattcccaat tttatgcttg gcaattgacg ccatcgtcaa gaaaaaaacc agaataggtg
     4621 cgattgcctt caagcaactg acaaacaacg ttcccaatat tgaaataaat gtccatgtgg
     4681 ggaaaaagat accaaacaat attccgacta aaataccaac aacaatacgt tgaactaacg
     4741 acatatccaa aaacttctct aacaaatgac caccctttca caattttaac aatcattgta
     4801 tcattttatg caaagaaact aaaggtataa ttttctaaaa attctaacaa tacaaacaac
     4861 catttcttgc taattttgta ctttttctgt ctacacgttg ttttttgaga tattctaagt
     4921 taggatgtta ttaatgggca acttatcagg aaacgttttc ttatgttttt gtccaatttt
     4981 tttgtgaggt gtttattctt gaaaaaaata aagaaggaga gttatggctt cctgacaatc
     5041 tttgtcgctt gtataatgat ggttttacag cgtatattga tttcagcagt cactattcct
     5101 acatatgcaa caaaccctgg tcgattctac atctatacat ttttacaaac ttccgttgtt
     5161 attggtgcaa atttgatccc actttacatg ggttaccaat atcaaaaaat cgcccgttta
     5221 aaagttttac attatttaag tcgttttgcc tttatattcc taatagccac actagtttgc
     5281 aatatctttt ttttacgtac aagctggcag cttgaatatt cgtgattatt ggcttatcct
     5341 aacacctatc agtcagaatt actttactta tgctgtttct tgtactttgc ttttttgtag
     5401 tattccttat acagttggat ttttaaataa attatcgaaa acaacaatta aatatctact
     5461 attattttta acaattggat tagttggctg ctctactcta tttaataaag acccgtttgc
     5521 attacagaat ggacagagta ttttatggat tttttattta tttttaatgg gttatggttt
     5581 gaaagaatgg aactggaaag aaaaggtccg ctataagctt cctcaagtat ttatcagctt
     5641 gattgtttta ttcggtttga ttattttgat gacacaaatt tcactcatca tcagaggaaa
     5701 tacagataca gcgctgaggt tttctaaacc atattctctc ttcgcaatgt attatacttt
     5761 ctcttcgttt ttatttttag aaatgctatc tgataaatta ggtataaaag gaagaggaaa
     5821 ttttcttgct gtatttttga ttgtcactca agttatatgt aatttccctt tagtttctta
     5881 tcgcgtatct acatttatga aacgtgaatt tccaaactca gggaaggcat ggctgataaa
     5941 tatcgggcag ttttttattt gctatttatt agcagtgtcc ctcctagtta tctttttatt
     6001 ttatatacaa aaaatccgtt tcattcatcg tttcatcgaa tacttcgctt ttgattcgat
     6061 tgaacaatta actcagcgtt ggaaaaaaag aattcattgg ctttttgttc ataaaagtta
     6121 ttttttagtt gcagcatttt tttactgctt taccttcgtg cagattttcg ttttagaacc
     6181 aaaagaaggt tggaaagaaa ctatccaggt tgccttaaaa atatttactc agcgacaagc
     6241 acccatgatc ctgacaatca tcattattat gggatttttc ttcttactat tgttgatttc
     6301 caatcgtttt tggtacgcct tgactgctac cttgatcatt aacttactgc tcactatttc
     6361 gacagtaatc aaaatggaaa tgcgggaaga gcctgtcttt ccttcagatt taaaaatact
     6421 gaccggattg tcagaactat tatcgatggt tagcccagtc ttattaatcg tgggcggatt
     6481 gatccttctc ctattattga ttactagtat tattgtacaa cgtagactac aaaaacagta
     6541 ttccttgaag attcattgga aacgtcgatt tatcagtatc gctgtattat taggatgttt
     6601 ttcgggtgtc tttttcatta atcacaaaaa ttcgccttct ttcttgctgt ttaatttatt
     6661 taaagtaaac aagactttct ttaaccagca aggcgccgta aaagataacg gaccagtcat
     6721 tcaattccta aacaatatcg acattaaaat catggaagaa cctgctggct attcgaaaga
     6781 aaaaattaat ggaataatga aaaagtacaa cacaaaggca gatgaaatca accaaacaag
     6841 aagtgactgg ttaaacaatc agacgatcgt tctcaattta agtgaaagct tcagtgatcc
     6901 tgcacgtgtc cctaatctga cagtacctac agaccctatt ccttacatca aaagcattat
     6961 aacagaagga acaggaggat tgatgttatc cgtcggttat ggtggcggaa cagctaacat
     7021 ggaatgggaa ggactgacag gcttgagtat cagtaacctg tctgcttcgt tagttacacc
     7081 ttatacccag ctagtggagc gtcagaaaat aagtccaaat attaccgatc tattcgatga
     7141 aaaaatagcc atccatcctt ttacagctgc tctttatcgc agaaaacaag tgtttgataa
     7201 atttggtttt gacaggttct attatttaga cagtccggat aaattaactt atacggataa
     7261 aatagaacaa agcccacgca tatcggatga ttcagcatac aaagaaacct tgaaagcttt
     7321 acaaagcaat acagaaacgt cacaattcat ccaattatcc actatgcaaa accatatgcc
     7381 ttatgatgat tactatagtg aattgaacta cactgctgaa ggaactgctg tcattcctaa
     7441 tagaagaaaa gaattacaaa cttatatgca aggccttcac tataccgata cagcagtaaa
     7501 aaaattcatc caagaaatcg acaaaatcga taaaccgatt acctttgttt tttatggtga
     7561 ccatttaccc gcaatctata gtgggaatga ttcgaaaaaa tatggattag aacagcacca
     7621 gacagattat ttcatttata acaacaagta tagtcgtgaa caagcagcta cgttaaataa
     7681 agaagttgtt gctcctaata actttggtgc tatggctctt gagcatgcga atatcaaagt
     7741 aactccttac tatgcgttgt tgacagaagt atctaatcat ctacctgcat taacaattga
     7801 tcctacagaa agcttgtcta atcgttttaa tggaaaacag gtctttgtta cagaggatag
     7861 tcaaattatc caagaaaaaa atttaactga gaaacaaaaa gaaattctag aagattatcg
     7921 tctgatacaa tatgatcttg ttgcaggtaa ccagtacagt gcaacatggg cgacacaaaa
     7981 aat
//
LOCUS       DAYYEF010000088         7822 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000088 DAYYEF010000000
VERSION     DAYYEF010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.092"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(207..539)
                     /locus_tag="ACHA1B_002628"
     CDS             complement(207..539)
                     /locus_tag="ACHA1B_002628"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703345.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(553..810)
                     /locus_tag="ACHA1B_002629"
     CDS             complement(553..810)
                     /locus_tag="ACHA1B_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703346.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(1005..1547)
                     /locus_tag="ACHA1B_002630"
     CDS             complement(1005..1547)
                     /locus_tag="ACHA1B_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF0163 family protein"
                     /protein_id="HFM8703347.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(1568..2659)
                     /locus_tag="ACHA1B_002631"
     CDS             complement(1568..2659)
                     /locus_tag="ACHA1B_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFM8703348.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(2667..4877)
                     /locus_tag="ACHA1B_002632"
     CDS             complement(2667..4877)
                     /locus_tag="ACHA1B_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CD3337/EF1877 family mobilome membrane protein"
                     /protein_id="HFM8703349.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(4893..7421)
                     /locus_tag="ACHA1B_002633"
     CDS             complement(4893..7421)
                     /locus_tag="ACHA1B_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM8703350.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLFLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVLNLICLDVAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEYKGLLQLEDELGTSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATIIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSFVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(7475..>7822)
                     /locus_tag="ACHA1B_002634"
     CDS             complement(7475..>7822)
                     /locus_tag="ACHA1B_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpE family conjugal transfer membrane protein"
                     /protein_id="HFM8703351.1"
                     /translation="TSNWRLPFPVALVNAATFLLVAIFEYLFLHSFIGWVISFFPPAG
                     VVFYIGIPYLCVLALAKLKPDGKKVHFYLWDWFCYVVRMMNGDCVYYNWDKVSNNALE
                     ELLFVNKYVYLED"
BASE COUNT         2391 a         1702 c         1138 g         2591 t
ORIGIN      
        1 atcaaaataa aaagttaatt catctactaa tttattcttt atttctaaat caactgtatt
       61 cactttttct gtggcataca cacttgttcc agtactaaca aaagtactta aacctaataa
      121 gaaaacacct aaaacaccaa atattttaat tattcttttc ataatttctc ctccataaaa
      181 aataagttac tttttaaata tcttgtttat gaattcattc cccaaaggcc ttttaagatt
      241 gatacagcag tccgttcact tcttttagac ttgtcataca agtcttttaa atgatcccat
      301 atcagactag tttgtctatc tagcttcaat ccattaaacg ctaatgaacg gttcattttt
      361 tctattactt tagataaagc tacagaaatt tttatacctt cacaacgcgc atcttggatt
      421 tcaataatag tatcatcaat tagtttttga atttcttgcc tatcaacata ttcaatctta
      481 gaaagagaat cttttaaagc tactaatgat tcaacgattt cttttttctc ttcagacatt
      541 ttcttcctcc ttctagtgac ccgtaaagcc atgtagagca gagtccattg aaccagtaat
      601 tacactatct acaacgccat tccaatttac tctacatttt ccatttttca gatttgtcgg
      661 tccatacgga tagccttttt gacattcaat gttcggatta taccagatag gattatacca
      721 ttcagccgca gaagcagatt cagtcgatac aaacaatccc acaccaacaa atccaataca
      781 catcacacta tagccaatta gttttttcat ctcgtatcca tctcctaaaa aatagaatag
      841 ttcttatagt tattcataag acatattttt tccgtttttg ttttatcctt tctgtcctat
      901 aacaactttt ttcaagtaaa gaatgacata gtttttctta aaaaaacagt ctgttttttt
      961 ctatttcttc ggtgtataat aaatatgagt gttcattttt tattttaata cgcactccgt
     1021 acataataaa tcttgatcgc atcaatcttt tgagcttctt gatctacttt caattgaagt
     1081 aatacaaatt gagtaacctt attcattgtt tcttctccaa ataacaaata ttgatccgga
     1141 ttctctatat cttgtgtcac ctggtaaagt ttcccagttg ttttcatttg tacatgcggg
     1201 tctacatcaa tactattgtc tttaatacaa cgatctgtca tatagtccct cacagcttga
     1261 ttgcgtttat aaacatctgt gaaattactc cattttctag caaaatcttt taagaaattt
     1321 tttgtcattt catctatttg catttgttgc gctgtctcgt cttctaatga accaatttga
     1381 ctgttacttt cagtactttg aagagttcca cttgtttctt ttactgcttc gattgtttct
     1441 tctgtcgttc tcaattgtgt tttttgtttt tcagaagaaa accaatgaca accagtaaga
     1501 cctatcaaac ataaccaact aaatactaaa attatccctt ttttcacgtt tctagtcact
     1561 gcctttctta tttcacctta cgaaccagac tacgaatttt tgtttgattg tacgtgcgtt
     1621 gataccgagc cataatccgt ccttgctcgg cattctgttc cacactagag aaatgttgtc
     1681 cgccatatga aacatctgtt ataattccgg tgtgaccata gattccagga gacaatgcac
     1741 cacctgcttg ccaattcacc acatctcctg cttgtaaatc acttggtttt gggttcatga
     1801 ttacttgcca accataggtt gtccagttat aatcttcccc tattaacatc gcaaacatgt
     1861 gtccagaacc cattaactgt gggccaccta attgagatac ataccatgcc gtaccaccat
     1921 aacattcccc attatttacg gatcgtccaa tgatccgatc caaaaccttc gcattgcctt
     1981 tactttttcc tgcaataagc gaagtttttt ttgttggtag gctattccaa tgcttgatcg
     2041 caaaagtatc atattccgtt aagttatagg acgttatgat actcattgct cctcgataat
     2101 acggactccc ttcggtaata cctgctgccg catagcctcc acgacctaga atcaataaac
     2161 aacttccagg atctttattg cccacacatt gattaaagtt gctttggctc gccaccataa
     2221 agccataata gtcataacaa gcttttaagt tcggaaactt catatagaaa ccaccttcag
     2281 aaccaccaat tccacgtgca gaaccttgtg ggtagggaca accaggaaac caggtaatcc
     2341 caaaaaagtt cgtatcgttt cttccagatt gtgactgtcc ataagctgat tcatagccta
     2401 attgagaaag aatcacactc ggtaataact gatactttac agctgcacca actgctgctt
     2461 gcgcatgttc atctgtgatt ggaccacgtc ctttaatctc tgaaaaaatc ggtaatcctt
     2521 cggtatattc cccattaaaa gcgacagcta gacctgtagc ttctcctcca tgctcagaaa
     2581 gttctcctga aaaaaagaat ggcaatagaa aaaagggaag aataaagaaa agaagacaac
     2641 ctagacaccc tttcttcatt tcttcctcat cctttcttcg ataatggttt ttggactgtt
     2701 cgtccttttg gtaaagtaaa atcagttcct ggttttgcgt ccaaaatcgg cagtgtttta
     2761 ggatcctttt ctattttttc cgattgctct gttggcttat ctaaagaaga aaatgcaggt
     2821 tgtaacgatt ttggtgcgga aatcgacggt ttactttcag acgaacgttg ccccggttgt
     2881 tgcacagaac gatttcctga tagagtggct accgacgaat taggaacaga gtattggttc
     2941 aataactgct gcattgctgg ataactccca tttttcgcct gatttttcac ttggcgaatc
     3001 tgttgtgaaa gagaaccagc agctgttaat tgtggcacgg gtacttttcc agaaggcaac
     3061 ggaatcgatt gaccaacaaa agcgatacct ttatttaaca atggttttct ttgattattc
     3121 ccttgttgct tactcaattg tgccaatgat tgtacctgtt gttttggtct tactgaattc
     3181 atggacgaat ttggaatcaa accatttgaa agaccagaat tccactctgt tttcgatttg
     3241 gtagaagaca tttcaggctc taccccatga taacgaacat gacgaccact ataaggcaag
     3301 gcttgatttg aacgcccacc tagttcaaag ggattaacca cttgcctccc ttttaccgat
     3361 tcttgtggtg tacgtttttg ttgaaacttt tgaaatccat gtatcgctgc agaagcgagt
     3421 ggattcgttg ctcgatacac attccctgct aatcctgcac ctttgattgc caaattttgt
     3481 ccagcagttg atagttgacc aggcagttgt ttcatttgag acaaagaatg acttgctatg
     3541 tttttcgtgt tgtttatagt ttgatctgca gctcctaacc ctagtttctt taataaatct
     3601 ttccgtttta caatgagtaa aattgatagg agtgctttga caaacatatt tcctaaaaaa
     3661 ccaaaaacag tattcattgg aattaaatcg tctactatgt tatagatcaa aaatgccacc
     3721 aaaataatca cactgtaaaa agatttttga aacatcaagc ccaaaaagga ctttaaggta
     3781 ttcatgagca tataatcaaa tactggaaca aaagaagcga gtaatgaaaa aggaatcaca
     3841 agtaataaac acaacaccaa catttgaaag ataaaacgaa tcatgccaat cactacaagt
     3901 ggtaatccaa tacttagatt aagcaatggc accatagaac caacgactgc tttataaaca
     3961 gctttagttg gttgaatata gacacgataa gccttctttt tccctctatc ttctcctgca
     4021 gcagtggtca cttttgtctc aatatcagat aattcttcac ttgacgcttc cttggctaga
     4081 aattcttgtg gttcaatctc tgcttgatac aattcttcta aatttgttgt cccataattt
     4141 aacaatatat acggatcaac aacagccgct ttataataaa gttggcgcac tttttgaatg
     4201 gcttcctttt gtgtcgttgg cactaaaaca ccattgacat cttttgtcgc caattcatct
     4261 agactatttg tagcagaaaa aataaagcct tctacctcca cggacaaatc atttaaccct
     4321 ttggtaaaag cttctccttt actaggtacg ttactaccat agccaaacca aaccattgaa
     4381 aaaatgacaa cgaagagaaa tcgaataaac accatttttg cgtaatgttt ccctctaaat
     4441 atacgaagag taaatagata taacacatac aagacgacaa tccccgcacc aataggatcg
     4501 tatatttttg aataaatagt atccgaaaaa gtgaaaaact ggtgaattaa ctcgttcatt
     4561 gcagctcctt catagagctt ctcaatgaca aaatcaaggc cttgccaaat caatttactt
     4621 aaactaaaga acatattcgt catcattttt agaaaatctg tgccatttgc cccaaataac
     4681 attttgccta atgaaaattc actatcagat aaataagaag aaaaggtatc aatatgaaat
     4741 ttcccaatct catagatcga ttgatccacc tgcttttctg ccgcatacac caatccacca
     4801 acaaaaagca gtccgaatcc aatcgttaaa aaaaacaaaa cgcaccattt cttttcctta
     4861 tgctttatat aagccattgt ttcacctcat ttctattgca tgattaacgt atcctgttct
     4921 tctacttgag agtgacttgt tttttccgtt gtttgtaatg cagcggtcat ttcttcaaac
     4981 aaactgtgta cattgagttt tcctacacgt ccatagggat ctaacatcca acactgtcct
     5041 ttaatcatgt ggctcatttc agctaagttc gcttcattta cttccaaacg taaatgattc
     5101 aaaatctttt ctcgctcact gtcttcatca aaagcaaaga cgacaccaaa attccctttt
     5161 tctttatctg aacctaagtc accaataaat tgtgtatcta acactaattg attcatctgg
     5221 gaacgcccca cacgtgccat tgctgcaata atactacgtc ctgcgttcga attattaaat
     5281 acccatgctt ctgtaaaata aatcgctgtt ttcttactac tatctcgttt tccaaacatt
     5341 tcacaaaaac gacctaaact aatcatcaaa cacaaagact ttcgatccgc atctgtatat
     5401 agttctggtc ggacattgtc atttggtaat ttcaaatctt ggatctctaa aatcgttgtt
     5461 ttggcattaa agtctaatcc cgggttttct ccataagaaa atcctaaacg taaaatcgaa
     5521 tcttctaccg tcaagcgtaa aaactcacca tattctcgaa cctctttttg ttccatttgt
     5581 tctaaatagt cgaccacatg catcaagcca acttgttgtc cggcttcttt ttgaactaaa
     5641 acttcttgga tcccctttaa taccgcccct tttaaaaggt gattggtacc taacggactt
     5701 aactcatcaa tcatatcctg ggctacttgt ttcgcatcta ctcgggataa acaaacaatt
     5761 ggatctaata cgccataatt acggggattt gtagcatcta acgtgacaaa actcattttt
     5821 tgcaaatgtt ccacaaacaa agggtaatgt ttctgataat acgggtcttg aatgagtttc
     5881 gtgaaccatt tgcgcttttc tcctttggga tctacaaata aactttgtac attcataaac
     5941 gaactataca aaaagagcaa accaactaaa aatgttttcc ctttaccagt ttttccagtt
     6001 actgctacat gaggcgcatc aaacaacgca cctttgattc cttccgcaat ggctaaaaga
     6061 tttaaaaaga caaagcgatt tgacgcgtag atcaattctt ctaacggtgt tttctctcct
     6121 ctagaaccac cgtctcctaa tgtatcttga cgaccaatat accagccgga ttccatacct
     6181 aactctgata ctgctgaaaa caaccattca ccaactgctt ctacagttgt tcggtgcttc
     6241 caatgtaact gccgtcccaa tggttgtcct aataaacatt tatagaacaa ttctcgttga
     6301 tcatttttag cacggtggat atggataatc gtatgaagct gttgaataat cgttgcacta
     6361 ttttgacgaa cttcttcaac cgtttgaccg tatacaataa aacatgcgat ccaatcgacg
     6421 acaggttgtc cattatctac tcgttgcttt aaatgtttta ctaatccccg aacagttaat
     6481 aagcgttcac taggttcttc atcattttga accaattcct tatgttctgt tttgaaccgt
     6541 tccgatagcc aattcagttt taaaccaata cctccctgtc ctttcaatcg tggatagtga
     6601 attttcattc gtaattctgc tgggaaagaa agatcctgtg caaattgaaa tagatcacaa
     6661 tttctcatat tttcaggtgt ttctccaata ggtaacaacg ctaaataact agtccccaac
     6721 tcatcttcta attgaagaag gcctttatat tccttcggta tacgtacata cgttccttga
     6781 ttgtctttca gtacttccca attattttgt tcttctactt tatgagccat tcctcgaata
     6841 tattgcagac gattgagata caacagctct ttttttacta agggacgaat agaaaagcta
     6901 taaagtaatt gtgtcacttc ttttacataa ggatcacttt cagaaaataa tgtttccaaa
     6961 tcatctactt ctaatccaaa taagcgtgct aaacttcctg ccacatctaa acagattaga
     7021 tttaatacat catgaaagct ctctaccgtt gctttttctt tgactttgat tcctaaaata
     7081 aatgaaggac gatagacttg cccttctcgt tctaacaatg tcactgtttc ttttgcataa
     7141 tacgcaccaa tggcttgact atcaggtgaa aatcccttac ctaaggtgtc aaactttgtt
     7201 cgtaaattca ttgttcgtgg atacatcacc aactccacat cttcataatc tgctaaaaac
     7261 aacagtaaac gagccatcat ttcttttatt tcctgtgtct tttttggtgt gttttttgaa
     7321 attgttcttg gaaaaacatg atagtaggcc cagatacaat cctctccatt taacaaacaa
     7381 tttttcttga atgctttcac tggttctttt acaagtacca atagatctca cctcccaatt
     7441 aaaaaaagga acaaccagtt gattgtccct ttttctaatc ctctaaataa acatacttat
     7501 tcacaaaaag taattcttcc aatgcattgt ttgatacctt gtcccagtta taatacacac
     7561 aatcaccatt catcatacgc actacataac aaaaccaatc ccataaataa aaatgcactt
     7621 tttttccatc aggttttagt tttgccagtg ctaacacaca taaatagggt atccctatat
     7681 aaaaaacaac ccctgctggt ggaaaaaaag aaataaccca accaataaat gaatgtaaaa
     7741 ataaatattc aaagattgcg accaataaaa aagttgctgc attgactaat gcaactggaa
     7801 atggaagacg ccaattgctt gt
//
LOCUS       DAYYEF010000089         7699 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000089 DAYYEF010000000
VERSION     DAYYEF010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.093"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            544..1107
                     /locus_tag="ACHA1B_002635"
     CDS             544..1107
                     /locus_tag="ACHA1B_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703352.1"
                     /translation="MSGYIYGYARVSTRSQELNRQLDLLNEQNCNEILTEKMTGTKAV
                     RPQLNRLKDKIRPGDTVIVESFSRLGRSTKDLIDLVTYFEEHHVKLVSLKENFDTSTP
                     HGRLMMTVFQAFSQFERDLIVERTKEGLKSARARGRKGGRPRVNQKDVDRAVKLYKSQ
                     VYSVKEITEMTGISKATLYRYLKDNRE"
     gene            complement(1386..1673)
                     /locus_tag="ACHA1B_002636"
     CDS             complement(1386..1673)
                     /locus_tag="ACHA1B_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFM8703353.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPNLLCGTHENFYEQLKKIR"
     gene            complement(1663..1992)
                     /locus_tag="ACHA1B_002637"
     CDS             complement(1663..1992)
                     /locus_tag="ACHA1B_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFM8703354.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            2297..2626
                     /locus_tag="ACHA1B_002638"
     CDS             2297..2626
                     /locus_tag="ACHA1B_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFM8703355.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(2913..3398)
                     /gene="vanZ-A"
                     /locus_tag="ACHA1B_002639"
     CDS             complement(2913..3398)
                     /gene="vanZ-A"
                     /locus_tag="ACHA1B_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFM8703356.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(3551..4462)
                     /locus_tag="ACHA1B_002640"
     CDS             complement(3551..4462)
                     /locus_tag="ACHA1B_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFM8703357.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(4890..5498)
                     /locus_tag="ACHA1B_002641"
     CDS             complement(4890..5498)
                     /locus_tag="ACHA1B_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFM8703358.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="ACHA1B_002642"
     CDS             complement(5504..6535)
                     /gene="vanA"
                     /locus_tag="ACHA1B_002642"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFM8703359.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(6528..7496)
                     /locus_tag="ACHA1B_002643"
     CDS             complement(6528..7496)
                     /locus_tag="ACHA1B_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFM8703360.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
BASE COUNT         2350 a         1532 c         1281 g         2536 t
ORIGIN      
        1 ttaaaacttt tttagcagat tttaaagttt cgtcaaaact aatatattct ggtagctgag
       61 cattcaaata gctttcagac ttcagaagaa aattacgagc atttttatag tccatctcta
      121 ataaagttat tcttttttta tccaatacat tcagctcaat tccttataat attctattcc
      181 ttagtatctc aacattattt actttataaa acgaataaat tttgtagttc taattcaaat
      241 attgcatgtt atatctaata tgggagcatt ttataatttt cattgtgata aactcgttat
      301 taactttagg atacactagt taggattaaa ttaggtatct agaaatttac ttaagatttt
      361 tttgtttatt tcgtatacac actcgtatca aaaacaatcg attatgagac aaaatgaaat
      421 gacctctttt attaaataaa agaggtcata ttttgtatca taacttgttg cattaactat
      481 gtatctataa ctccctttta tgatacaatc aagccagaat taaagtacga aaggaagaaa
      541 agcatgagtg gatacattta tggttatgcc cgagtgagta cacgttcaca agaactaaat
      601 cgtcaattag acttactcaa tgaacaaaat tgtaatgaaa tcctaactga gaaaatgacg
      661 ggaaccaaag cggttcgtcc ccaactaaat cgtttaaaag ataaaattcg tccgggagat
      721 acggtaattg tagaaagttt ttctcgattg ggtcgtagta caaaggattt gattgacctt
      781 gttacctatt ttgaagaaca ccatgttaag ctggtgagct tgaaagaaaa cttcgatacc
      841 agcacgcctc acggacgctt aatgatgact gtcttccaag catttagtca gttcgaacgt
      901 gatttaattg ttgaacgtac caaagaaggt ttgaaaagtg cacgtgcgag aggtcgtaaa
      961 ggtggccgtc cacgagtgaa ccagaaagat gttgatcgag cagtaaaatt gtataaaagt
     1021 caggtttata gcgtaaaaga aattacggaa atgactggta ttagcaaggc aacactctac
     1081 cgctacttaa aagacaatag ggaataatct attttaatct ttaggaatct ataatattta
     1141 tgggagaatt agagtgattt ttttattatt actaaaaaac aatataaaat aacgcatttt
     1201 aagccctctt tgtgcataag gatgaagctt ttaatttgaa agaggcttaa aatgcgtttt
     1261 aattttttct atttttcata aatatatagg ttagtggttt aaaattatag ggtattacaa
     1321 ctctcagctg ttaaaaatta tcttttaaag tgtcgtctat cctctcaagt tgaaacattg
     1381 ggttcttacc taatcttttt taattgttca taaaaatttt catgcgttcc acatagtaag
     1441 ttaggtatca ctgcattatc tttaatttca tatgcaacgc gatatgtcgt acctgcatac
     1501 ttgaatccaa tagcccaaat tcctgataaa tcacccgttt tttgttctcc cgaatgagga
     1561 cgaactgcta tctcatcata aattatcgtt aaaaattgtt cttttaatgt tttctctttt
     1621 aattttttta gatactttat tacgtgttta gaaggtagaa tctcataagc caatttctgc
     1681 tgccaactcc tcttttgtca tcggtttaga atttgcaaca gtatcttcag caatagattt
     1741 aaatgcagaa gttaacgcat tttttctatt tctaaattct tttaagatct cttgtttgct
     1801 ataaccttct gaaagaatat cagccaaaat atcttcacta aaatcaaaaa attctttttt
     1861 aggctctaca aactcataaa ggataccatt ctctacaagc ttagcttcta cttcaacacc
     1921 attgggcaca tcgaattctt tagggaccgt taacataata gaatttcctt gttttcttgt
     1981 ttttgtaatc atattatttc ctccattatt ttacatttcg taattactta gtaattacat
     2041 tgtacgctat ttttagtaga aatacaaaat aataaaactc ctttagaaca attttcaaag
     2101 gagttttatt tgattaggaa attatgtaga ataataatat gtttttaact tggaatcaaa
     2161 aacgcacttg caagtaagtt tacttcaata catgaaattg cttataatag tgtattggaa
     2221 ttaaggtaga ttgacaaaag agtgatcaaa taggtatact tcattcaaat aatcgtttga
     2281 atgtgaggtg agatgaatga aaaaagtttg ccaagtgact gtcgtacata aagaaaaagt
     2341 aaatggaata aaaaataaat tggatcaaaa agatttttca aacttacttg tgttagggaa
     2401 atgtttcagc gatttttcta gaattaaaat tttctatgct ttagaaacct ataaggaaat
     2461 gtgcgtctgt gatttagcag aaatacttac tgctagtgtc gctacaacgt cacaccattt
     2521 acgtttttta aaaaaacatg gaatggcaaa atcacgtcaa gatggaaaag tagtttatta
     2581 ctctttagcg aatgaagaca tcctttccgc tattcgtgtt ttttaaagtt atcagaaaat
     2641 ctatctatga aatcttagtt tgggggtacc gtcaggaaaa tgcggattta caacgttaag
     2701 gaaatttatt aaagagacca attcctcagc actaaaattg ataattgggc tttctttgtt
     2761 actatagtgt taggtaagct ttttacttta tcaccggttt tcccctcact tcacacctac
     2821 gggcgagttt ccccacatcc cgttttccat ctaatccaat tcattcaata tctttatgtg
     2881 tatgaaagat cagattgctt gatttagaca tcttacacgt aatttattct taaatgggta
     2941 cggtaaacga gcaataatac gagcaaaagt atacctacaa aaataataac tctgtctaat
     3001 tttttttgat tcatatgctt attgcttaaa ccatataatt tcagtccaag aaagcctcca
     3061 acagtatttg taattacatc tgttatgtct gtcgctccaa tagcgaagat aaattgaatt
     3121 atttcaaaag taagacttaa aaccagtaca aaagcaaact taggtaaaaa tccgatttct
     3181 ttaaaattga cattcaaaag caagccaaat ggaataaaga ttataacatt atctatcatc
     3241 tctctgaaat tcccagtagc agtaaatgga gtcaagttaa gacttctttg atgataatta
     3301 aatactgata aaatattgta ttgtaatttg aataacacta accagattag tgtcactaaa
     3361 tataaagcta gcaatcctct agataatatt tttcccaata taatttcctc taattctttt
     3421 gtttaagttg tatcattagt atagcaatgt cctagttaac gtgggtttta aattaaaaag
     3481 ctaacgttac cccaaaagtg ctagtacaat aatgctgttc attaatttcg ttggtttcat
     3541 tccgccatcc ttacctcctt gaattagtat gtgttgatcc gggaaacact gtcacaatta
     3601 caccgtctat attgtttcct gatatctcat aacgaagatt agtcggcaca tgaatggtgg
     3661 tatttttagt aacaggataa taaaagatct catatttttc cccatttaca ctaacagaaa
     3721 tggttttttc ttcttttagg taatccatat attcctcgag aacgaaattc ttttctttca
     3781 taatcgcact atgtggtaaa ccaacatagc gaatatgcca tggttcatat tgaattcctg
     3841 ttaactctgt tttgtcctct ggataacgta aaatgaaccc gtatttccaa gcattttctt
     3901 ctatccactt tccttcaggg gctcgttcca ttttcgtcaa gcttgatcct acatctagtg
     3961 ataaacctga attatgctca ctataacctg ctggtaaggc atactcagcc cccatttctt
     4021 ggtaaagcac actttgctca tcaaagtctc gatagccact attaataata aaatgactaa
     4081 cgccaccctt tacagcatca ttgaccatct ctgaaaattt ttgtgctatt tcttttgaca
     4141 tataaatatt actatcaagc aacccgtatc catttattaa ttcgtcatgt ttagataaat
     4201 tcacgatatc tgacttcaca ctttcttggc gaacaggata tttactattg attaatagca
     4261 gatttccttg ataaacctgt tcttctgtaa ttgttttctc ttgggtattt tcagaagtcc
     4321 cactattttc taaatgttct ttgggatttt gatcataatt ttgaaattcg actttttcct
     4381 gagaaaacag tgcttcatta acgtagtcat aacctaagta tattaagaat aacaataaca
     4441 ataaaaaaaa caacttcttc attttcagtc tcctccttaa ctatatagtt ggaagtatga
     4501 aatatttcta gaatcttccc cttaaacggc acaatctcgt ttgagattgt gccgttttgc
     4561 cccgtaaatt acagtcaatt atttcgccct actggattta ctattatcac caatgtagat
     4621 gaattttcat aagtgatacc catgctgaat ttaacgaggc tgaactgcct gttgacaatg
     4681 ggcggtgtga aataccaccc ctctatgcga tcagtcttat tatcaggcta tcttgccgca
     4741 gcgcacgcag ataatgaccg caatatcgct ctgccttaca tcttcaatac tatctactat
     4801 atataaattc cctaagaacc agttacatac gtcgggtttc ctgccgaaag agttagctta
     4861 tatagtttgt ccgtgcaacg gttaaaagtt tatttaacgg ggaaatcaaa atagctattg
     4921 gggtatggtt cgtctcttaa tacatagtgc caccattcga ggctatatgc ttcaaaccca
     4981 ctgttttcca tgatggagcg caaacgtctg cgattttgcg cttcattgca tgatattcca
     5041 tttgccgcat gatgagagcg ttcatccata aaatcaaatc ggctccccat tggtacaagc
     5101 tcacccgtgt ctaatcgata aagcgtaaga tcaatggcac tgccgcggct atggcttgat
     5161 tttgaagcca cgtatccttt tgaaatcatc tcagttcggt caatattggg ataataactt
     5221 tcctttgtca ggttattttc cggctgtgca gcccattgca taaaacagtt tacagcacga
     5281 ttaggacggt aaccgtccca tagaagcaat ccgtaccctt gggtagcagc cagttctttt
     5341 gccttcaaaa gcgattcagc caactcgtat gtccctacaa tgcgatttac ttcataaccg
     5401 tcaaccggtt ttccggtgaa attatcccaa gtggcatatt tagcgtccca acgaacaccg
     5461 tgtactattt catctaaaaa agtaaatcct atttccatgc ttatcacccc tttaacgcta
     5521 atacgatcaa gcggtcaatc agttcgggaa gtgcaatacc tgcagcggcc atcatacggg
     5581 gataacgact gtatgacgtg aaaccgggca gagtattgac ttcgttcagt acaatgcggc
     5641 cgttatcttg taaaaacata tccacacggg ctagacctct acagccgagc gctttatata
     5701 ttttttttgc cgtttcctgt atccgtcctc gctcctctgc tgaaaggtct gcgggaacgg
     5761 ttataactgc gttttcagag cctttttccg gctcgacttc ctgatgaata cgaaagattc
     5821 cgtactgcag cctgatttgg tccacctcgc caacagctaa cgcggcactg tttcccaata
     5881 ccgcacaacc gacctcacag cccgaaacag cctgctcaat taagattttg ctgtcatatt
     5941 gtcttgccga ttcaattgcg tagtccaatt cgtccgcgct attgactttt ttcacaccga
     6001 aggatgagcc tgaacgcgcc ggcttaacaa aaacaggata ggtaaacgta gctgccaccg
     6061 gcctatcatc tttattaata acccaaaagg cgggagtagc tatcccagca tttttcgcaa
     6121 cgatgtatgt caacgatttg tccatacaaa ttgctgagct ttgaatatcg cagcctacaa
     6181 aagggatacc ggacaattca aacagacctt gtatggatcc atcttcacct gacttgccat
     6241 gcaaagctga aaatgctaca tcaacatggt tgatttcata ttcatggttc tttttaacaa
     6301 gtaatccgtg cattttttta tccggcgaga gtacagctga atagcaattg tcgttttccc
     6361 attccgcgca aggtttttcg cacattttcc atacaccaga tttcgtaatt ccaatgtata
     6421 acggctcgta tttttcttta ttaatgttag cggctatctc tattgcagat tttaccgata
     6481 cgtcatgctc ctctgagcaa cccccaaaca gtattgcaac ttttattcta ttcatgctcc
     6541 tgtctccttt caaaatccaa acagttttta atggtttttt caacggtatc acgcaacgct
     6601 tgctcggtat aataggccgt atgcggtgtg attatcacgt taggcattct ttgaagttta
     6661 agtaaaaatt gattatcaat tggtttttgg gtgcaatcag agtagaaaaa ctcttcctct
     6721 ccttccaata catccaatgc ggcaccgccc agtttcccgt tttctaatgc tttaaccaac
     6781 tcataggtat ctacaagtgg accgcgccca gtattgataa gaaatgctcc ttgcttcatt
     6841 ctctgtattt gttcgtggct gataatatag tgcgtatccg tattgagcgg cacatgaagc
     6901 gtaacgatat cgctattttg cagcaactca tcaaacggta catagtttac ctctatactt
     6961 cggctgcgac tataagccaa cactttacat ccaaatcctc gcagccgctc aataaccgct
     7021 ttgcctatct ggcccgttcc caccacacca actgtcatgt cgctgagtac cttgccacgg
     7081 tcgctgtcca acctgaaatc atgtttttcc acagagcgca caatcgattt tacgttgcgt
     7141 actgccataa gaattagcat catagtataa tcggcaacgc tatccggcga gtacgccaca
     7201 ttgtcgacag tgatgcccat tctcttagca gcagttgtat ctatatgatt gcagccgatg
     7261 cttcgggtag aaatatattt cacaccggct ctcttcagcg caagaagaat agaggcggaa
     7321 atctctgatt tatgtcccac actgatacat tgattgaaag gcgcggattt ggcgttggat
     7381 tccgacacgt tggcgttaat tatcgttgcc ataacgccaa agcgaggcga aagagcatgg
     7441 aatgcatctg cctcatcctg ctcacatcca taaacagtaa tgccgatgtt attcataatt
     7501 aagaccaacc ctttctgtga aaggcaccaa ataaaacggg gatgccaatg gtaatcttgt
     7561 caaatctttc tctgaagaac gaaaacggct cgttcttacg gtattaagtc taccgtgtaa
     7621 gaacgagccg tttcttaata ttaaattgtt aatttcctaa gaaaaagtaa agataacctt
     7681 gagattttcc taaaaaatt
//
LOCUS       DAYYEF010000090         7600 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000090 DAYYEF010000000
VERSION     DAYYEF010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.094"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(137..427)
                     /locus_tag="ACHA1B_002644"
     CDS             complement(137..427)
                     /locus_tag="ACHA1B_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703361.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(545..805)
                     /locus_tag="ACHA1B_002645"
     CDS             complement(545..805)
                     /locus_tag="ACHA1B_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703362.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(942..1355)
                     /locus_tag="ACHA1B_002646"
     CDS             complement(942..1355)
                     /locus_tag="ACHA1B_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HFM8703363.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1811..2296)
                     /locus_tag="ACHA1B_002647"
     CDS             complement(1811..2296)
                     /locus_tag="ACHA1B_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703364.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2435..2650)
                     /locus_tag="ACHA1B_002648"
     CDS             complement(2435..2650)
                     /locus_tag="ACHA1B_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HFM8703365.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2874..3674
                     /locus_tag="ACHA1B_002649"
     CDS             2874..3674
                     /locus_tag="ACHA1B_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFM8703366.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3693..5561
                     /locus_tag="ACHA1B_002650"
     CDS             3693..5561
                     /locus_tag="ACHA1B_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HFM8703367.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5554..6045
                     /locus_tag="ACHA1B_002651"
     CDS             5554..6045
                     /locus_tag="ACHA1B_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HFM8703368.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6033..6587
                     /locus_tag="ACHA1B_002652"
     CDS             6033..6587
                     /locus_tag="ACHA1B_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HFM8703369.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6605..7600
                     /locus_tag="ACHA1B_002653"
     CDS             6605..7600
                     /locus_tag="ACHA1B_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HFM8703370.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2708 a         1213 c         1443 g         2236 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      721 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      781 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      841 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
      901 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
      961 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1021 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1081 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1141 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1201 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1261 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1321 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1381 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1441 tagctttgtg aatatttcat ctaatacgat acaaaggcta tctttctaat ttgaaaaagg
     1501 gatcattaaa ataataagaa gaaaatatgt caaaaggtaa aaaagtaaat tcttctatcc
     1561 aaatatagaa aaattgaatc tagaaaaccg cccgacaata aatttcatta actcagttga
     1621 ccgaaaatga agtagatacc aaaaatttat caagagagca agtagagaag tgagtatatt
     1681 cataagagaa atagctgtaa cgaattatta ggttaatgca aatgcttatt tatactccgt
     1741 ataactttct cagaaaaaat gataccaata atgacttgct agtactgtaa atccgtataa
     1801 tatcatctaa tcaaaatggt gttccatttg catctgtcat cgtaatcgat ccttcgggtg
     1861 acactcgata aaaaccaacg cttccagatc ctccttggga acggatttgt ttgctggaag
     1921 ctgtgaacaa ataatctcga tcaatttttt gataaaagct aataacaata tcgtcacttt
     1981 gtaattcgga acggtgggca ataagaaata gaagtgcttt gtcagagttt tctaatggaa
     2041 gagaaggtac agtgctttct tgcatttcag atgttgaaga aatgctaaac gactgaatac
     2101 ttgattggct atgttgcgaa tctacattac cagtagaagt attagtaatg gaagtagtag
     2161 aagtactttt agttgaacca acctcagttg ttgaaatggc tgctgaagat tctttaacag
     2221 aattctttgt tttatatcca caggcagaaa aaagtattac agttcccaac aagcctgcgt
     2281 aaatcccttt atgcatgata gctcctccta aaatagatta tctttattca gtatatcact
     2341 taaacaaaga aaagcagatg gtttaaaatg aaaaaacctt cccaataaag ggaaggttca
     2401 tgaagataat aactttttta ataattatag ctttctaata tctttcatca acttttctag
     2461 taatcattgg gaaaaatttc aagcagtaga tcgcacaaat acctacgacg atataaatga
     2521 tcttcgcaaa aatagttgtt gaaccaccag caatcatagc tactaaatca agttcgaaca
     2581 agcctaccaa cagccagttc aaccctccca caatcaataa agttaatgca atagcatcta
     2641 aagttttcat tagaattctc ctttcttaaa tgataaaaca attatatatc aaaaagagaa
     2701 acattgctta tataacgctc aggaatttta gcaatctatg caaaaagatg aaaatttttt
     2761 ttgctcttcc attagtacac attttttagc tgaagctgta aatttcatgt cttaattttt
     2821 tttagtgagc ttttatactg gatttgtaag aaaaaagaag gagaggatca catatgtcgg
     2881 attggttgga tattgcagga aaagtagtaa ttgtaactgg aggttcctca ggaattggaa
     2941 gaagtatcgt cgaaaatttg ttgaagcaga atgcacaagt agcgaatttt gatgtaactg
     3001 aatgccgtat acagcatgaa aacctactat ctttaaaagt cgatgtgtct tctaaaacgg
     3061 acatagaaga agggatatat aaagtaatga aacatttcaa gacgatcgat ggtctagtca
     3121 ataatgcagg aataaatatt ccttctcttc taatagatag aaatcatcca aaaagcaagt
     3181 atgaattatc agaacaagtt tttgataaga tgatcgctgt caatcaaaaa agtgtatatt
     3241 tgatgagcca agcagttgga agaatcttgg tgcaaaaggg atcaggagtg atcgtgaatc
     3301 tttcttctga atcaggattg gaaggatcag aaggacagag ctgttatgct gctacaaaag
     3361 cagcgatgaa cagttttact cgttcttggg caaaagagtt aggaaagagg aatgttcgtg
     3421 tggtaggtgt tgcaccaggg atactggaag aaaccggttt gagaacacaa gaatatgaag
     3481 aagctctttc ttatacgaga ggtataagcg tcgaacagct gagaaacggt tacagtcgaa
     3541 caagtacgat ccctctagga aggagtggta agctgcaaga agtggcggat ctagtctgct
     3601 attatctttc agaaagatca agttatatca ctggagtcac gactaatatt tcaggaggta
     3661 aaacaagagg ataaaggata ggggggacgc acgtgacgct agtaaacaga tggtaccaat
     3721 tattgaaatt actagtcact cacaagaaag tttcaatcca ggaagtgcaa aaagaaatca
     3781 aaaccagtaa tcaaaccata aaaaaagata ttggggagtt gaatgaagaa attgccggta
     3841 ttgcaaaaat catccaaaaa aacaaacatt ttgaacttga aatttatgat tttgattttt
     3901 ttgatgagat catgcaagga aaattgaaaa cagccagtga tttcaattcg gcatccaaaa
     3961 gaatcgctta tttactaaat aggctgatcg aaacagagga tttcttacgt atggatgatt
     4021 tgtctgaaga agtcggtgtc agcagaggaa cagtggtcaa ggatctaaag acattaaaag
     4081 agatgatcaa tgattttgat gtaaagatta caggcacacc aaataaagga ctaagaataa
     4141 taggagatga gctagaatta cgactacttt tattttattt tgtttctccc tacttttcag
     4201 agacgaaaac agaacagttt ctagaagaaa aacaagcaat caaacatttt cagaagaaga
     4261 cgaatgctag taaacaagaa atcacccttt taacgaaagt tatcggtatt tctttgaata
     4321 gaatctctag taactatctg ttgaagaagc ccatcaatcg ttacagtggg tgttttgaat
     4381 atatccaaga attcaatgaa ctgatcaatc agttggaaga aatctatgaa ctaactttga
     4441 gccaatatga aaaagatttt atcagttttc ctttgaacat catcaacaca agtataacga
     4501 tgataaggaa agctaactct gatttgcgct tatatttcga ccccatgatg atgcgtattc
     4561 gacgattaga tctcattgat ctggatgagt ccttcttata tcaagagatg aaacagcacc
     4621 tctctttatt gataaatcgg gtaatttttc gttatcgatt gactgattta ttttatggtg
     4681 agatagaaaa aaagtatcct ttttcttacc aaatcgctag cgaatgcata caagcattag
     4741 aagctatctt gcaacataag atctctaaag tagagatcag ctacctaacg ttgtatttgg
     4801 agttagcatt tcgatatcaa aaagagcatt tttcctctaa aaaagtagcc attgttcata
     4861 cgacaggaaa aggaacagca ttaatgatcc aaagacaaat caaaaggata ttggggaggg
     4921 atatacaaat aacacatgtt tcagaagaac aatatgaaaa agtagatcta aacaaatatt
     4981 tcgctgtttt tacaacgatt ccgttaaaaa atgtaaatga agagacaccg gtgatccatt
     5041 tgactaatct ttttgatgac tcttggttaa gggcacaatg gcaaaaagca aaaaaaaagc
     5101 gattagccgg gtttcattct actgtttttt tctatcaaat atggaaagaa aaaaagacgt
     5161 atcaagaata tttaaacaaa ttagtcgctc ctttgatcag aggctattat gtggatgaag
     5221 aatttgaaaa aaggatcttg aaaagagaat atcagcaaag cacatttgtt aacaaagaat
     5281 ttgcttttcc tcacacaacc aaccagctat ctcaacacat tgttttatca gtagggctaa
     5341 taactgatca aggtttagca gaaacaggag gaaatggagt tattttttta tttgccatac
     5401 ctgaagaaat gacggctgaa gttgagaatg aattatttga gctatacgat atcctatttg
     5461 aactcataaa aatgggaata gatgagttta ttgaattagc accgacacaa gaatcatttt
     5521 taaaactaat caaaagtaaa ggagagagac ttcatgaatg atatgtatct attcatagtt
     5581 ttcgcagctt cagcttatgt gctgcaagca gttatcagtt ggaagcaact aaagcatttc
     5641 aatcaaacat atagcgaact gcgaagaaaa ggaaaagtag cgattggtaa acgacctggg
     5701 aaaatccgtt caggcacgat tgttatgcta gctatagacg atcatgatca agttttagaa
     5761 gtcagaaaaa tgcaaggggt tacatctttg gcaaaatttc attcattacc tgtctatgcg
     5821 ggtgaagata tccattacat cgatcgttac catccctcag ttcgagcgga agatcgtttg
     5881 acacaagcag ctttagaaaa tgccagagaa gtatacttac gaatagaggc aggaaatgaa
     5941 aaaagtgaac aaccttcatt gccttttatt gctatgctca ataattttcg gatatggaaa
     6001 agtacgatca aagaaaaaag gagtgacaaa cgatggatat cataacaaaa tttgctgagg
     6061 gatttatgag gctgttccaa acaggtgcag aaacattcat aagctggatg acaggaatcg
     6121 taccagttgt cttgatgctg atggttgcaa tgaatacgct gattgctttt ttaggtgaag
     6181 accgagtaac gaaagtagcc aaattatcag cgaaaaatcc gcttactcgt taccttgtgt
     6241 taccgttctt atctgctttt atgttgggaa atcctatgtc atttacaatg gctcgtttcc
     6301 ttccagaata ctacaaacca agctattatg ctgctcaagc tcaattttgt catacgagca
     6361 atggtgtatt cccccatatt aatcctggag aattgtttgt atggatgggg attgctcaag
     6421 ggatcgaaac cttagggcta aattcgatgg agctggctat ccgatacttg cttgtgggac
     6481 tgctgatgaa ctttattggt ggttggataa ctgattttac tactggattt gtatgcagac
     6541 agcaaggaat cgttcttagc aaaaaagtag agctttcagt tgattagaga aaggagagtt
     6601 ttaaatgtat ggtgatatta agatcgtaag aggaaacggc gggtatggag gtcctttgat
     6661 tattaggccg acaaaagata aacacaagtt catctatgtc acaggtggag gtgagaggcc
     6721 aatgatcgta gataaaatag aagaactgac aggtatggag tctatcaatg ggttcaaaac
     6781 atcaatacct gatagtgaaa tcgcgcttgc aatcgttgac tgtggaggga ctcttagatg
     6841 tggaatttat cctaaaaaag ggataccaac catcaatatc gtttccacag gaaaaagtgg
     6901 cccattagca caatatatca ctgaagatat ttatgtttca gcagtagggt tagaacaaat
     6961 acagccacta atggaaactg atgataacaa agaaacagta aatactgcat ctccagataa
     7021 aaagtacaaa tatgatactt ctaaaaagat aaccgagcaa aaagcagagc agcaaaactg
     7081 gatagcaaaa attggaatgg gcgcgggaaa agtagttgct acattcaatc aatcagcaag
     7141 agaagcagta gatacgatga tccggacagt gatccctttt atggctttcg tttccctttt
     7201 gattggtgtg atacaaggtt ctgggatcgg taatgtattt gctaacatta tggcaccttt
     7261 agcaggaaat gcagttggat taacaatcat tggctttatt tgttcactgc catttttatc
     7321 tcctttgctt ggtccagggg cagttattag ccaagtgatt ggaacattga tcggtgtaga
     7381 gattgggaaa ggaaatattc ctccccaatt agcattaccg gcactatttg ctatcaatac
     7441 tcaaaatgca tgtgatttta ttccagtcgg tctaggtttg gaagaagcaa aagctgagac
     7501 agtagaagta ggtgtaccat cagttcttta ttcaagattt cttaacggca tcccacgagt
     7561 tatcattgct tgggtagcaa gttttggatt atatagctga
//
LOCUS       DAYYEF010000091         7537 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000091 DAYYEF010000000
VERSION     DAYYEF010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.095"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            107..1248
                     /locus_tag="ACHA1B_002654"
     CDS             join(107..335,335..1248)
                     /locus_tag="ACHA1B_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFM8703371.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1483..1935
                     /locus_tag="ACHA1B_002655"
     CDS             1483..1935
                     /locus_tag="ACHA1B_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703372.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            1949..2638
                     /locus_tag="ACHA1B_002656"
     CDS             1949..2638
                     /locus_tag="ACHA1B_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703373.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            2763..5114
                     /locus_tag="ACHA1B_002657"
     CDS             2763..5114
                     /locus_tag="ACHA1B_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="HFM8703374.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            5194..5589
                     /locus_tag="ACHA1B_002658"
     CDS             5194..5589
                     /locus_tag="ACHA1B_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703375.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            5914..6531
                     /locus_tag="ACHA1B_002659"
     CDS             5914..6531
                     /locus_tag="ACHA1B_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703376.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            6572..6871
                     /locus_tag="ACHA1B_002660"
     CDS             6572..6871
                     /locus_tag="ACHA1B_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HFM8703377.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            6905..7072
                     /locus_tag="ACHA1B_002661"
     CDS             6905..7072
                     /locus_tag="ACHA1B_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFM8703378.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(7117..>7537)
                     /locus_tag="ACHA1B_002662"
     CDS             complement(7117..>7537)
                     /locus_tag="ACHA1B_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703379.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2594 a         1138 c         1502 g         2303 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc gtagaatcta actactaaga aaaggacgtg tccacgatgg caaaagccaa
      121 gaaaaaattt gatgaagact ttaagaagat gatcttagat ttaaaccagt ctggccaatc
      181 ggtcgaagaa ctggcagcgc aatatggtat cgctacacaa acgatttatc gttggaagaa
      241 gcttcataca aagaatgtag caaccggcat gactgaggca gaaatcctag cgatgaaaaa
      301 ggaaatggcc cgcatgcagg aggaaaacac tatcctaaaa aaggctttaa ccatattcgc
      361 tcaaaagtaa aaatgagtga tgtcttcgaa tttattcaat caaatgttca tgatcatgac
      421 gtaaaacaaa tgtgtaccgt tttggaagca ccgaaatcca gctactatga ctggaagaaa
      481 aagaaacctt ccaagcgcca atcagaaaac aaacgcttaa accgcttgat ttcaggaatc
      541 tactttgaaa acaagggtat ctatggtgcg cctaaaattc ataagattct tgttggccgt
      601 ggcgagacct tgtccttaaa gaaagtacaa atactgatga gaaaattagg cttgcgttca
      661 gtcaccctca agaagtacaa gcctggcaaa caagcgaaag ttaaaagtga aggacgtaaa
      721 aacctgttaa accaagattt taccactacg tcgatcaatc aaaaatgggt gacagatatt
      781 acctatattc ataccctaaa agatggctgg acctacctct ccactattca agacctccac
      841 acaaagaaag tcatcggttg gaagtttggc aagcagatga cgaaagaatt ggttatcgaa
      901 acccttgaca atgcgctctt aaaccaaaca ccctccgaga acttgatcat ccactcagat
      961 ttgggttctc agtacactag cgaagcctat gaggcaaagc tgaatgaatt gaacattcgg
     1021 cactccttca gtcgtaaggg ctgtccctac gataatgccg gtatcgaatc gtttcacgcc
     1081 tcactcaaaa aagaagaagt ctatccatca aaagcgtatg aaaactttga agctgcttat
     1141 ttagcgttat ttcaatacat tgaaggattt tacaatcgca agcgaatcca tagtagtatc
     1201 aactatttaa caccaaatca gatggaggag ttggcattgc aagcttagtt cctagctacc
     1261 acttacattt ttttggcgag atttccacag ggtttcaact tcatcgcttc gatcagcggt
     1321 caaacggttt tggtttgacc gctggtcgaa acgatgagat actcacccgc tggaatctcg
     1381 aaaaaattct cacaaatcgt gtccgaggta ttgactcaaa tccaccaatt atcttatcgt
     1441 agatatatat tataaattta ataagaaagc gaggtgagaa tcgtgaaaaa aacgatacta
     1501 agtatttttt cagtatttac aatattaatt gggggctatt ttcttttgaa tttagattct
     1561 gttaattcaa acgctcaaat aaaagatcaa agagtagctg aacataataa taaaaaaatg
     1621 agtttgacca aaaatatcta ttctatgtca gatgaagaat tgtataaaga atttggtgat
     1681 ttatccgggg aacagttaga agaaagtatt ccaggaatta gtgactcaga taaaattgtt
     1741 gtcttgtctg ctggtgggca attaatggga gatggcaaat ccgaattagt tagttataaa
     1801 caaaatcaca gacagtttat tgatgttaat actgattcca acgctatttc gattaaggat
     1861 ctaaaagagc ttttaaatag taaaagaaat gaattaaagc agataaaaga aactaattca
     1921 gtggaattag agtaaaggaa gattcattat gaaaaagatt tttggtgttt ctgttgggct
     1981 acttatgatg ttaacatttg gaaatgcagt atatgctgct gagaaagaag ttatttcaga
     2041 tccagagcag tacgcctcac gatactttgc tgattttgaa gaagaagata aagtacttgc
     2101 attgccagaa ggtggttttt taaaagggga agctaaaatt gtatctatgg ataatccaga
     2161 tataattcaa ggttcatata attcagaaac tgatcctgct tcagtttcag tgacagaagc
     2221 aaaaaaaatt gttgctgaaa aattcaaaaa tgatattgaa actactccaa ttatgcctcg
     2281 aggagcattt ccacccgatg ttggtactag cggacacctt cttgtactag caggaggagg
     2341 aagctataaa tcacagccat ttagtggtgc gggatggcgt tttggaggta tgggtgtaaa
     2401 accagctgat ggtacaggca actttttacg ttggaaatcc tacattgacg atggaagagt
     2461 aggaaatgta aatcaagcca acgcaactaa atctggttct attcaaggaa tggcattgta
     2521 tgctcgtgaa ggattcaaat actttgcacc aaacgggcct ggttggacaa tgaatatagg
     2581 tatttattac acttataatc ctgttgcagg tacgtattat gttgttcaaa atatttaata
     2641 aaacagcaca aagagatttc tttgtgctgt tttattattt ttagttgttg acaaacacta
     2701 aaatataaaa tataatcaac acataaacga acgtatgttc ggcaagaaag caggggattt
     2761 ttatggatga gatggtttta agtactcaga aatggctaaa caagaaatac agtaatgtta
     2821 cagggtttga taaggttcca gaaaatgggc gaacagggtg gcctacaatc tatggactta
     2881 ttgaaggact acaagtagaa cttggtatta ctaatctagt agctaatttt ggacctacca
     2941 ctgaaaaaat gtacgataat caggttactc ctaaatgggg caaaaatcta cctaaaaata
     3001 ttgtatttct tattcaaggt gccttttggt gtaaggggat taatccaggt ggcttcgatg
     3061 gggtatatac tccatattta gatactgctg taaaagagtt gcagactgat gcagggttta
     3121 atggaagcgc tgtaactgga gttttggatg cgaaatgggc caaagcgtta tttgatatga
     3181 gtgcttttgt tcttgttccc ggcggagata gtaaaattag aaaaatgcag caatggttaa
     3241 atgtaaatta tttagaatac acgggaataa tgccttgtga tggtatttat caaagaaatt
     3301 caaatcaagc attaattttt gcattacaag ctgaactagg atattctccc agtgaagcaa
     3361 cagggtctta tggtaatggg acaactagta aaacttatcc tgtgtctgaa ggtaactcgg
     3421 gaaactatgt aagaataatt caatatggat tatatgttaa tggttatttt gaagacggta
     3481 cattcgatgg tattttcact aaatatatgg gtttagaagt actggcattc cgaaaattta
     3541 tggtattgcc tgaatatact gaaatagcag atgttgttgt aataaaagga ctattgtcta
     3601 gcgctggaga tattagaaga tctgcagatg gcgcagatac ttctacgcaa ttaactagat
     3661 ctcaaatcca aacattggtt gataatgata taaaaatagt tggtagatat cttactggta
     3721 ctgttggaat tggaaaagat gaacgaaata agtatctaac tacagaggaa ttgaataata
     3781 ttttttctaa aaatttatct gtgtttccta tctatcaaga tggaggtgca gcattagctt
     3841 attttactta tgatcgtggc ttatcagatg gtaagaaggc tatagatgca gcaaaaaatc
     3901 taaatatacc attaacaaca gttatttatt ttgctgttga tctagacatg ttaggggaag
     3961 aaattcttgc atatgctgga gaatatttta agggggtatc tgctgtaatg tcatatagcg
     4021 ggtatcaaac gggtgtttac ggaacaagaa atgtttgttc tcaaataatc aataacgggt
     4081 atgcttcgtt tgcatttgtt tcagatatgt cgactggtta tagtgggaat ttaggttttc
     4141 ctatgcctag acaatggtct tttgatcaat ttgttgaatt taccatagga agtggcaacg
     4201 gagctgttgg tatcgattta atcgctacat cgggtagaga tagcggattt aatgagttat
     4261 caaatgatac taataatgat aattacattg ccaaatacaa tcagaaggtt ataaatcaga
     4321 tggtacgtgc gtatcaatat ctatcacaag ctggtcttga taatccttgg aaccctcatt
     4381 tgacatttta tagatatgta aattattctg gtttgtcatg ggacatcatt tcttctcctg
     4441 taacagagca tgatagaaaa atttatgatg aatataggaa taaattaact aatagcgagg
     4501 gcctgtataa ttattttata gatcctaata ctggttcaat aataggtttg cctcacttaa
     4561 ttgtgacgtt acaatcacag atgtttctag ccgacacaat caatgatagt gtttctgact
     4621 ttgcaggttg gttaggagat ttaatgactt gctggggtga agttaagaaa ttaggaatac
     4681 aaatggagca aggtgtattt gcattagtag gtacggctgc aggtggaaca tttagtctag
     4741 aagatttata ccaagatgtt gacgcggtaa atgtttatac cttagcaaaa agaaattctg
     4801 attcaacagc tttatcggct ttaaaaacgt actattgtga taagggtgct attgatagat
     4861 ttaatcaatt tgttaagaac agatttggtt cttcagataa aatcgcttca gtaacaaata
     4921 gtttattaga aaatgacgaa acagttgata tcttaggtgt agggataatt tcatttttca
     4981 ttgataaaat agttaataat tcacttggga cagattttac ttatcttgat tttattggag
     5041 atgaggggaa agttgcaaat ggattttctg aaaaaattat tcaatttcaa gaaaatagaa
     5101 gtaaacttaa ttaagaatcg tttactattt aaacagtgtc cttttccttt ttaaatatat
     5161 acgataaaat aagtatatga attgtaaaag gacatgatga ttatggaaga aatagaatgg
     5221 aataatctga ctcaaaataa taaaaataat tctggatgtg gaattatctt tatgtttgtt
     5281 atagttttgg gaatagtagt acttttaata actgtcaaga tagtagatta ctttgcgaat
     5341 actcctgaag aacaaataca gagaaaactt cctgagtttg aaagagtacc accttatgat
     5401 ccaagagata attcatttca agtaaaaaaa ttaaaagagt ctccaaatga aatgtggttt
     5461 gaagttacag ttgaatcaag cgacttcaaa gaaaaaaaga aagaatacaa ttatattgta
     5521 aaggcaaaag tatcaaaaag atttattttt aaccctaaat tagaaatata tagtgttgta
     5581 atagaataat agtgttaaaa aaattgtaaa agttaaagaa gtcaaattct gatgtgaaaa
     5641 ataaaatata ccatggaaga cataaaagaa aaactggata actagtttat ttaatggcag
     5701 accgttaagg cctgccattt ttatgtattt tagcggaata aatataatca tgcgggagtg
     5761 taaacttact gtttcaaaaa gtatactttt tgacatgcct tgattttctt tgtttatgta
     5821 tggcataata accacataat acaatttgaa acgtttctga tttaatctga ttgttttgaa
     5881 acaattttag tgaaaaaagg gtagataaaa acgatgagaa aattttttta tatccgggtc
     5941 agtagttatg atcaatcgat cgaacgacaa ctgatttccg cgaaggaatt aggaatccct
     6001 gaagaatata tatttgtaga aaaagccagc ggcaaagatt ttaaacgccc tgaatatcaa
     6061 ttaatgaaac ggatgtttcg aaaaggagat ttactctatc tacaatcatt agatagacta
     6121 ggcagaaata aacaaatgat tttagaagaa tggcgagaat taactaagga aaagcagatt
     6181 gatatttctg tgttagacat gcctctgtta gatactgcta gttacaagca actagatggg
     6241 ttagagacgc ttatctctga cttaattctg caattactca gctatatggc cgaagacgag
     6301 cggaaacgaa ttaatagccg gcaaagagaa ggcgtagaag ctgcgaaaca aaagggtgta
     6361 aaattcggca gaaagaaaat tgctttacct cctgaatttc ctgcgatcta ttctgactgg
     6421 aaagcaggaa agataactgc agtctatgct atggatcaat tgggcatgaa acgaaatacc
     6481 ttttatcgac gggtgaaaga atatgaacat accttgcacc acttttcttg atagatataa
     6541 cagctattag acgggaaggg agagtttgaa aatggactta acgaatcaaa gggtcgtttt
     6601 tactggaacg ctgcagcaaa tgacacgaac ccaagccatc ggtttggttc actctttaaa
     6661 cggccattgt caatcaagtg ttacttcaaa aacaaatttc ctggtttgtg gtcagtattc
     6721 taagtcgttg tttgatgatt ctctctatac aaaaaaggaa caaaccgcgc gggacttgat
     6781 tgcgttaggt catgagatta ccattttatc agaagtcgaa ttttatgcgt taattagtca
     6841 acagttgaaa gaatggcaac ggtatttata atcgttagta aaatttacaa ggaggaaaat
     6901 ttttatgaag cgaaaatctt atgatcgttg gggcattgaa ataactagtt ttaatcgaaa
     6961 tattgctttt cacgtggagt gtgactgtgg ggaattagca aaaagtgttt atcaaaaaaa
     7021 ttacttttac tgtcctaaat gccatcgccg atacggggta catggaacat agaaacgaaa
     7081 tagtgcggta gaaaagcgaa tgaatgtagt atatttctac aaatcattcg ctttctttat
     7141 tttataaata gttggtcgag agatcccgtt ttcttttgca atctctgcaa ctggaatgcc
     7201 ttgctttaac atgtccacca cggttttaaa aactaagcgt ttttgcggat ctgttgagtt
     7261 aatagaatac tcgattggtc gtcccttata tcggccggct ttttgagcca ataatactcc
     7321 ttgccgctga cgttcacgaa ttttctcacg ctcgttttgt gcaatataac ttagcagtga
     7381 taaaaacata tcgaacatag cggtatccag gagttcattt ccagtattaa aatctaaaaa
     7441 ctgtgcatct aatattttta acgctacttt tttctgtttc ataaaagcaa ctgtattttt
     7501 tatatcttca taatctcttc ctaaacgatc tagtgat
//
LOCUS       DAYYEF010000092         6908 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000092 DAYYEF010000000
VERSION     DAYYEF010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6908
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.096"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..217)
                     /locus_tag="ACHA1B_002663"
     CDS             complement(<1..217)
                     /locus_tag="ACHA1B_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
                     /protein_id="HFM8703380.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYYQKLTDNPIGFGLLPEDDEGNE"
     gene            complement(836..1168)
                     /gene="traE"
                     /locus_tag="ACHA1B_002664"
     CDS             complement(836..1168)
                     /gene="traE"
                     /locus_tag="ACHA1B_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HFM8703381.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(2015..3055)
                     /locus_tag="ACHA1B_002665"
     CDS             complement(2015..3055)
                     /locus_tag="ACHA1B_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HFM8703382.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
     gene            4221..4307
                     /locus_tag="ACHA1B_002666"
                     /pseudo
     CDS             4221..4307
                     /locus_tag="ACHA1B_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            4861..5085
                     /locus_tag="ACHA1B_002667"
                     /pseudo
     CDS             4861..5085
                     /locus_tag="ACHA1B_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877485.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            5345..5599
                     /locus_tag="ACHA1B_002668"
     CDS             5345..5599
                     /locus_tag="ACHA1B_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HFM8703383.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            5600..5917
                     /locus_tag="ACHA1B_002669"
     CDS             5600..5917
                     /locus_tag="ACHA1B_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008657 - DNA topoisomerase type II
                     (double strand cut, ATP-hydrolyzing) inhibitor activity
                     [Evidence IEA];
                     GO_function: GO:0042803 - protein homodimerization
                     activity [Evidence IEA];
                     GO_process: GO:0030541 - plasmid partitioning [Evidence
                     IEA];
                     GO_process: GO:0051290 - protein heterotetramerization
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HFM8703384.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            6476..>6908
                     /locus_tag="ACHA1B_002670"
     CDS             6476..>6908
                     /locus_tag="ACHA1B_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703385.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNM"
BASE COUNT         2346 a         1094 c         1042 g         2426 t
ORIGIN      
        1 attcattacc ttcatcatct tcaggtagca agccgaatcc aattggatta tcagtcaatt
       61 tttgatagta taaatcatcc tcgtctaatg ctaaaacatc taatccttta caatttccgc
      121 ctcttctaaa cgtcacaaat cctttgtaat cccaacgttg gaaagaaacc ttaatagtat
      181 gtgtgcccaa tcgtatattc ggatcataat ttttcatttg tcattcctcc attacgtaaa
      241 tttcattttc tctatgtttt atatcaattt tttcacttta ttcaggactc gttcatattt
      301 tatcgttttt cgtttactta aaaatacata aaaaatatcg actcgtttat ggcgtccgaa
      361 acgagaaacc ctagtagaaa tcggtaaatg ctcgattgat ccaatgacca acgtcctcgc
      421 aagtatctac atgtactgca gcacacgaca caatttcttg tgcgtcctcc ccattacgag
      481 aagacctact ccttattcca tgagtttgcg tcaaagccta gatcccttag tagctgctca
      541 tgattaatct aggcgctatt ctaacttgtc taacttctaa attccctctt gtttactctg
      601 tgcatattat ttacacaaat tcatttcacc actatccaaa caagggcatt tactcgattg
      661 accaattttt tacgttacca atcgtaaaaa cctaccccgt caccccccga aaggaattgt
      721 tgatagatca agtctactcc ttatttttct agtaattcta agttctttta gaagtctcga
      781 caatattttc aagcaagcga aaaacgataa aatacaagtt atgagaatga tcaattcagc
      841 tgattaaacg ccccatccct tttgcggtac aacgcaagac tccatttttt cttcgaccaa
      901 tcagtacacc gttttggtca taaacatgtt tgattgttgg atatagttct tttaaaggga
      961 taggatcttt taaaattatt tgcttttgtt taccagcgta ataaatcatt tcctctgaga
     1021 ctttgtcttt ctggattata tatttcttac actgcacaac ggttttactt tggccagttg
     1081 atagtttctt cgtgattttc tctgtagcgg tacaccgttt accgtagtga caaatatctt
     1141 cgagactcaa aattcctgta tatgacataa aataatccac ccacttactt taaatatttt
     1201 taataagttt ttcttgttat ttttcaaaaa tagagaattg attttcgttc atgacaaaca
     1261 aaaaagaggg aacgcatcca aacatgcgtt ccctctaatt tcagcgttcg tcatacggca
     1321 aagagccaca cggacatttt tataacatta tgcttaggca tagattcatc gtaatatcac
     1381 gtatttttaa ccttaacaca gccaaaaaaa gtggtatcac ttttgaatat ctgttatact
     1441 aaatccgttg cgggtaatac cgtaacactg aaaggtaaac gcattaaggg attaaaggtt
     1501 gtcttaatgc cacctgtgga cgtcgacgaa ggttaccagc cttccgagtc tcacagggcc
     1561 tttctttttt ttgtattttc aattgtccaa atttatcgtc caaaagtgca gaacgaaaat
     1621 taattcatca caagcgtagc agacaattaa atttaaaaca actaaattta tacaaaaaaa
     1681 tgtaagcgaa taatattcgt attgcctgaa aagaagtaat atcaaggttt ttagcttttt
     1741 taaaaaatga aattacctct cttcgcgtat tattataact aaaaaacagc aacatgcaaa
     1801 cgtttgttct cttttttgtg ttggaaatta attattaact attaacactt atgacgtaaa
     1861 aagctacgtt tgtgattttt atcataatat tttaactcat aaattctatt aaaatagcta
     1921 tttctttgta acatttgtaa tataattaga ataataaaaa atttttaatt ttaatgctac
     1981 tccatgaagc aacaatcaat ttgtcagtga aatttcactc taaccagtct ttcgtaatag
     2041 tttttgggaa gctttcagaa ttcaaacgtt tttcacttga tactttagca gctattggtt
     2101 tttcgataaa ccaatttttt acatagacaa aaatcaggtt ctggatattt tcaacttttt
     2161 cggtttttaa tttttgatag gcttttaaca gtgtcgtgta taattcttgt tctgcattga
     2221 cataataact atcgagttct tcaaaaatta ttgaaatacc actttctgtt tcggcttttt
     2281 tctttgcatt atgaatagtc tggacagttt tttgagcttc actgtaactt gaagaaaatg
     2341 tttttattaa atttaatact cgttcaggga taaacgtagc aatgctgtcg tttgtcataa
     2401 ttgtctcaaa attgtctaac aacaattgat cttgtaggcg gtctttttca gtgtctatat
     2461 tgtgtctatt agtgtctaat atattattat taagttctgg tatgattttc ataccctctg
     2521 atttatcaac gttttggcac ggtatgattt tcataccctc ttgagcccca agggattcag
     2581 cgtctgattt ttcgtcgagg gtgggtatga ttttcatacc ctctgattta tcaacgtttt
     2641 ccctattctc tctatcaaat ttttcgagta agtagatatc attttctgag acttttaatt
     2701 ctgctagata tagtctatta ggattatttt tccctaactg tttgttaaat cccatctgct
     2761 tttgtaataa taaaccaaag gattccaact cttttttgat tgctatcgct ttttgttttt
     2821 ggcagtttaa tacgctacat agttcatttg tcgtataagt aaaataaaca ttaccttctt
     2881 catcgatttg ccgtttgctg attgcgatct ctaatcttgc ttttaaaagc atataggcaa
     2941 tcttagttga atctttcatt tttttgtatt cgtcagaaac aataaagact tttggaaatt
     3001 gataaaataa ttcgttgtaa actctatccg ccttaaaaaa attaaaatca gtcattgtag
     3061 atcctctact ttcacgttgt tttatttatg taaaattacc tactcttttc gaaaatagca
     3121 aagataaata aaaaatgcaa acgcattaaa actgtttttt aattaaatac tacctaaaat
     3181 cagaaataaa atgaattatg tactaccttt aaagtcatta agaactactt taaataaata
     3241 ttatttataa ttaaatacta ccagaagaac gtatgaataa aatttagttt taaaattaaa
     3301 gataattaag tactaccagt gtcaaaacaa aaaataaatt aagaactacc ttatgcatat
     3361 aaaacatact accattacta gtaatatata ctaccttatt tcagtagtat atattatatt
     3421 cttcttataa gacaaggctt taggctagaa aacaatagat tatatactac taaaaaatac
     3481 aataagtact accaatgtca gatatatata ataattatgt actaccatta aaattaactt
     3541 atttaataag atactactgt gttaatctga aaaaaattac tttaaagtag ttacatacta
     3601 cctgttaaat tagatactac cattaatact taaattagat actacctata tttatattaa
     3661 gtactaccgt tctaggaata agataataaa aaaaaactac caaattgcaa ttaaatacta
     3721 cttaaaatgt aaaaaataag aactacccaa attaggtagt tcttaataag agaatatcag
     3781 ataaatttgt acaagtcata aaaaaattaa tcttaaattt ttaaatatat atacctgtta
     3841 attataaact actttattta ggtagtacat aattaacaga taaaactaca tgcttgtagt
     3901 ttgtctagct aatgagttgc atatgattta tataaaggtg tgcagcataa cttagttgaa
     3961 gttaagagaa tagaataaat attttttgtt ttgctaataa ttaaacacta cctaaatatg
     4021 gtagtgttta attatataat attcattttg ttacaaataa tcgtattata aaagcataac
     4081 aattgggata actatttttt agattattta agtactactt aaattaggta gtacttaaat
     4141 tttggtttaa ggtagtaggt aattaagaaa taatatatat cttcttttat aatagaaggg
     4201 gagaggccta gttaaaaaca gcgacaatta ataacaatgt atttaatgct tcacaaaatc
     4261 catttggtgg acaatgcatt gttattagcg atgatctacc gttctaagta gttttttcta
     4321 ttggttgcat tcgtgactaa ttatggtata attatgagta acaaagaggt atttcattat
     4381 atcatcaaac cccatcagcg tgtaggctga tggggttttt tttacgtttc tatattatag
     4441 aattaactgg taggcttact gtcttttttg gcaattttgc aatcaagcca cttgcagatg
     4501 tagtgtgcag ttacctctgc aaatggcttg attgcaaaaa caaaatcaaa aaggtatttc
     4561 attatatctc ctcctcccct tgccagatta ggccggggta gcagacagca aaactattat
     4621 aacataactg aaatacctaa atgacatata cagatatgat aatttatgta ttgatttttc
     4681 taacaaaagc acatatttta atatatacta cctattttag gtagtatata tttttagata
     4741 caatatcgat cagttttgag gaaatgaaat tctagatatt ttttgctaca tagagttact
     4801 ttcaatattt tttaacgtaa ttaggcagaa gtcactcatc ctctataggt ttgtgatgaa
     4861 attgctattg atccatttaa gtaagagcaa aaaactggag gtttatcagg taattggtct
     4921 aatggattta agtatgcggt caccgtgtat agagttgctt atgagattca agaaaataaa
     4981 gttattccag tattgctata tggaacacat aacaattttt atgaattagc cgagaacact
     5041 cgcaacttta ttcgtgtaga tgaatcggct tcggttgagt tataacttta gctatatcaa
     5101 tcaaccgacc gacatatgtt aaatctatat ataataaaaa tacctactta aatggatgtt
     5161 aacggaagtg tatggtgagt agttcactcg tattttgata tcgtttgtat atgttttcag
     5221 cgttctaagt ggcttatttt gtccaataat aatatggagt ggaatccctt aagaaacacc
     5281 gttggcaatt gtcgttataa catgttataa tttatttatc aaaaactaaa agaagtgtga
     5341 taacatggga aaagaactaa aggttagaaa gatcggcaat agcgtgggag tgatccttcc
     5401 aagctctctt ggattaaaaa gcggagacac tatccaagcc aaacaagaag gcaacttatt
     5461 catattagat actactcaaa tagcaaaaga acacgatcgc aaattgattg aagaaagttt
     5521 ccaagacttt gagaaaggtt taacagtttc agaaattgaa atggtaaaag ctttcggaaa
     5581 atacggctgg agtgaataga tgaaagagta cacgctagtt tattctaaaa gtttccagac
     5641 cagccttgaa acgataatag aagaatggga aaatgagctt gctctttctc cagccagcat
     5701 aaaaagattt gtaggtgcga tccagaaggc tttagaacta accaaaaatt ttccaactat
     5761 gcatgaggaa gtttccgaaa tctatggaat ggatatccca acatatcgga tcgtgatcgg
     5821 caaaagctat gccttatttt atcggatcga ccatgaaaaa aaagagatac ttgtaggacg
     5881 tattttccaa tctaaacaaa tgaaactagg cttttaacaa taattaggca aaagtcgctc
     5941 atcctctaca ggtgggtgat taatgccgct cgatatggtt gttaaccgtc ggttactcga
     6001 agattgatat ataagactta gtaccttttt attttgctcc atgttatggc cgaaggtcta
     6061 aagatacaat cattagtcta gagaaaaatt aagaaccgta ggaactacgg ggatcgcttg
     6121 gtgaataaga gacactgcta ttagtgaaaa aataagatat caagtacgct ctattcccaa
     6181 aaatttcgtg actttactca tgagaggttc aagtagtata tttttaatca aaattgacgt
     6241 aacttttaat aaatactacc taaataaggt agtatttatt tttgtgtttt aaaagaggaa
     6301 gtccaatata tctatgggaa acttcttaaa tattatgttg gtacatgaaa atatacatcc
     6361 ctgctagact atttacaaca ttttactttg tacgtattct tgttttaaaa ggaatgggat
     6421 aaaatatagg tacaataact atttgatgct aaatataatt aatggaggag agatagtgaa
     6481 catacttaat gaaaaaagat atgtatggtt tgctggtaaa aaatatatta ctactttcaa
     6541 aagattatcc gagttaatgc agcagactgt taaaagtgct atgcctgaag gatacaagtt
     6601 taattttgtt caatcttcag tatctactga aagtatctat ttttcaattc tttctgagag
     6661 taggcttttt cattttagaa taagttctca tgtaaagaaa actgatgttg atatatatac
     6721 gttccgtaca aataattata aaaatttaaa tgatttgagt agaagtatca gtgaatatct
     6781 caaggggaat agctatctca agattcgatt ttcacatata ttaattttac taccatattt
     6841 gaatgagaat ttcaccctaa ttcaagtaga taagtctttc attgcctcag gtaatcaagg
     6901 aaatatga
//
LOCUS       DAYYEF010000093         6602 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000093 DAYYEF010000000
VERSION     DAYYEF010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.097"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            215..577
                     /locus_tag="ACHA1B_002671"
     CDS             215..577
                     /locus_tag="ACHA1B_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR/SmtB family transcription factor"
                     /protein_id="HFM8703386.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            594..1205
                     /locus_tag="ACHA1B_002672"
     CDS             594..1205
                     /locus_tag="ACHA1B_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HFM8703387.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(1307..2215)
                     /locus_tag="ACHA1B_002673"
     CDS             complement(1307..2215)
                     /locus_tag="ACHA1B_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HFM8703388.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(2257..2571)
                     /locus_tag="ACHA1B_002674"
     CDS             complement(2257..2571)
                     /locus_tag="ACHA1B_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="HFM8703389.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            2870..4801
                     /locus_tag="ACHA1B_002675"
     CDS             2870..4801
                     /locus_tag="ACHA1B_002675"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFM8703390.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            5094..5645
                     /locus_tag="ACHA1B_002676"
     CDS             5094..5645
                     /locus_tag="ACHA1B_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8703391.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            5958..6500
                     /locus_tag="ACHA1B_002677"
     CDS             5958..6500
                     /locus_tag="ACHA1B_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBECR4 domain-containing protein"
                     /protein_id="HFM8703392.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         2179 a         1090 c         1273 g         2060 t
ORIGIN      
        1 ttcttgaaaa aaaataagag tatagagtat gttctttata aaattaattt tcgtgtaaat
       61 gattaaaaaa tttaataata aaatttaaat tcctattaag ttgtaacaca tgaaattgct
      121 tataatagtg tattgaaatt aaggtagatt gacaaacgag tgatcaaata gatatactac
      181 cttcaaacga ccgtttgaat gtgaggtgag atgaatggaa aaagtttgcc aagtgactat
      241 cgtacataaa gaaaaagtaa atgtaataaa aaaaaaattg gatcaaaaag atttttcaaa
      301 cttacttgtg ttagggaaat gtttcagcga ttcttctagg attaaaattt tctatgcttt
      361 agaaacctat aaggaaatgt gtgtctgtga tttagcagaa atacttactg ctagtgtcgc
      421 tacaacgtca caccatttac gttttttaaa aaaacatgga atggcaaaat cacgtcaaga
      481 tggaaaagta gtttattatt ctttagcgaa tgaagacatc ctttccgcta ttcgtgtttt
      541 tttaaagtta tcagaaaatc tatctatgaa atcttagttt ggaggaagtt attttgttac
      601 aaagtatttt ttcagctatc gctgtttata tttctaccag tattgattat ttgtttatct
      661 tgctgattat cttttctcaa agccacacaa aaaaaggtat tcgtcacatt ttttggggtc
      721 aatatcttgg aacaggtatt ttggtagccg taagtttgtt tgctgcttat gtgctaaatt
      781 ttattccgca agattggatc attggtcttc tcggtctaat tccgattttc ttaggaatca
      841 gagtcgcttt tgttggcgaa gaggaggaag aagaagagga agtcgttgaa aaactcgaat
      901 ctagaggaac taatcgctta ttctggacag ttgccttaat aacgattgct tctggaggcg
      961 ataatttagg tatttatatt ccatacttta cctcgttagc tttttcagaa atcattattg
     1021 ctttaatcgt attcgctatc tctgttgcgg ttctctgcta tatcagttac aaattagcca
     1081 agatttcttt tgtttccgaa acgttagaaa aatacgaacg aatcattgtc cctataatgt
     1141 ttattgcgtt aggaattttt attatgatag agaacgggac gatacaaacg ctactaggtt
     1201 tttaaaaatc ataatcacga aagataaaaa gagaggcagc gactaatcaa aatcgctgcc
     1261 ttttttgctt ttcaaataat gaagtatttt ttagcgtaga actatcttac gtgttgtggg
     1321 agtatccctt ttcaagctct tctttgcttg tagttatttc tattgtgata tgattctcta
     1381 cgcttgattt gtgtgcgact tctgcaattt cttcttttat ttccctagcc ttgtctatgt
     1441 ctgaagggtc tataagaacc gtgatgataa gggcgttttc ttccccgtcc agtgaccaaa
     1501 tgtgaaaatg tgagaggtct tttacagcag gaacattttt aatggagtcc gccaagctct
     1561 ttacgtttac attttcaggc gaaccattca ataaaatttt cattgtggtg aaaaattcag
     1621 gaacggtttt gtagaggata taaagtgcaa tcaaaatcga taagatagga tccagacgat
     1681 atgcctcggt aaagttcatt agaatactca caatcaagac tccaatccac cctaatacgt
     1741 cttccagcat atggaggttc aacatgctct cgtttttgga tgtgcctttg cttaaaatcc
     1801 acgcagcata tccattcaat gcaatagcta cgagagaaag ccagaacatg ccactataat
     1861 ttacgggttg tgggtcaatc aaacgtggca cactacgata gatcataaaa aacgagccac
     1921 taattagcac aacgccagtt atcagcgcgc ccagtaaaga aaagcggtta tagccaaaag
     1981 tgaaccgttc atcttgtttt ttctctgaat aaccttgaaa aaaccaagcg aatccaattg
     2041 aaatagagtc ccctaaatca tgaactgcgt cggacataat ggacacacta ttgaaaagaa
     2101 agccaaagaa aaattcgctt atagagaaaa taagatttat gaagaaagca attttaatat
     2161 tctttttcgg ttgattctga ttcgagtgat tatggtcttt atctgatttt gacatttaaa
     2221 aacctcctaa gtttgtatgc tacatactaa ttggttttat ttttctaatt cattaacatg
     2281 agttaagact tgttcgagaa tactaaaaac atgaaggtca tctaaactgt aaagcatact
     2341 ttttccttct cttcttgatt tcactaagcg tgcgtctttc aacgttttta attgatgaga
     2401 aatagcggac tgttccatgt ccagagaaat agcgatattt ccaacactac actctttttt
     2461 ctgtaaaaga aagagaaccg acaatcgtgt aggatcacta atcaccttaa atagtttgct
     2521 tattgacaga atagatcctt tatcgattgg agaagttgtt tttatatcca tagtgttttt
     2581 attcctttca tatgaccttc cgttcatatc tatattacca tatgagcgaa acaatgctaa
     2641 tcttttgttt ataaaagaga agtggcgttc tctttatctt gacaaaatgt atatagcgat
     2701 ataaaatgag tatacaaaca tatgattaat tagtcatatg taaggtggat tcattacgat
     2761 ttacttttgg aataaacgaa aggagtcaga aatagcagaa atttatgtga ttcaagaagt
     2821 aaatgatgga aaacaaagga attataaatt atatagggag gcaatagaag tggaaactat
     2881 ccaagaacaa cagtctcaag aaaagcataa tcataatcac aaccacgatc acgaccatga
     2941 tcatgggaaa atgccagtcg ttttgtactt tgttggttta gcattagcag tgattgctct
     3001 atttttgaat gaagattatc agttggtaca aaatgttttg ttctcaatcg ctacaatcag
     3061 tgccgggtat cacgttattc ttcttgaagg ccttggagaa acaattgaga attcaaaagc
     3121 acaaaaaaag ttcataccta attctcatat tttaatggga ttagcggcaa ttggagcttc
     3181 tttgatgggg aatttttggg aaggaacatt attgattctt attttttctg gcgcacattt
     3241 tttggaagat tatgcagaag gaagaagcaa acgagaaata acgaaattac tcgaaatgaa
     3301 tccaacgact gcccggttaa tcctgcctga tggtagtaca aaaaatgtgg atgtcagtga
     3361 attaaaagtg ggagatcaac ttcaagtgtt gaatggcgat caagtaccta ttgatggcgt
     3421 cattttgtct ggatctacat ccattgatga gtcgtctatt actggagaaa gtatcccgaa
     3481 agagaaatcc aaaggagatg gcgtcttcgg gagtacaatc aatggaacag gtaccttcac
     3541 gatgaaagtc accaaagaaa acaaagatac agtattttca aaaattttac aattagtgaa
     3601 tcagaaccaa gataaccaaa caaaagctgc gagtattatc caaaaatttg aaccgaaata
     3661 tgtcacagtt gttttaattg ccattcctct attcatgtta ttggctcctt ttctacttga
     3721 ttggacatgg tcacaaagtg tctatagagg attggtcctt ttagttgcag cttcaccgtg
     3781 tgctttagca gcagctactg tctcggcaac gctatcgacg acttctaatt tagccaaaaa
     3841 aggagtcctt tcaaaaggta gttcttacct gtctcaatta gccgatatta aagcaattgc
     3901 atttgataag acgggcacct tgaccaaagg aaaacctgaa gtaaccaatt attattttgc
     3961 tgattccgtg aacgaagaaa acatgattga tatcgtagta gctcttgaaa aagaatccaa
     4021 tcacccctta gcagatgcta ttctaagaaa gtttgagcaa aaaaacaaac taactattga
     4081 agtagaaaac caaattggta aaggattgac gggagattac aaagggagaa attatcgtat
     4141 aggaaaaccg acttcgtttg atgatgtttc agatgaatat agtcgtttaa ataatgaatg
     4201 ggcgtcagaa ggtaagacag tcgtatacgt agcagtagat gaagaggtta taggccttat
     4261 tgcccttatg gacgttccga gtgaatatgc taaagaaacc attgaatatt ttaggaaaca
     4321 aggtatacac accacattaa ttactggtga ctcagaaatg acgggaaaag cggttgctaa
     4381 acaattagga atagatgaag tgattgcgaa tgtcatgccg gaagacaaat ccagaattat
     4441 agacgaacaa aaagaaaaat acggcgtgac cgccatggtt ggagacggtg taaatgatgc
     4501 tcctgctctt gttaatgcag atgtgggaat cgctatggga gatgggactg atgtggcagt
     4561 agaggtatct gatttagttt taatgcaaaa caatttatct aaattggtac aatctcataa
     4621 tatttcttcg aaaatgaacc gtgttatttg gcagaatatt attttttcaa tggccgttgt
     4681 tgctttttta attgtcgtta gtttcttagg cttaacggat attgcaatca gtgtcattat
     4741 tcatgaagga agtactttgg ttgttatttt gaatggactt cgattgctaa aggcagtcta
     4801 aagaatgatt gcacaacttc aaattaatcg agtaatagag ataattaagg attacactac
     4861 attttttatc tctattactt gtttatattt atctagatgt tcaaagtcaa aatgatatat
     4921 caaccatact cttgtggcgc gggttgaata taagatacat gaaattggat aaaatcatgt
     4981 atcaagaatc ctatccttat agggttcttt ttttttactc cccctaaaca cacgatttcg
     5041 tgttgtaata actataatca tgtattcgaa cagactaaaa aggagggatt gtcatgggct
     5101 ataatgttca gccactacgg tcgcaacagg agattaatga ttttttattt tgcctgcgac
     5161 ggaataaaaa tgcggaacgt gacgttttct tgtttctaat tggaattaac agcggtctgc
     5221 gcatgtccga catcgttaaa ctcaagaaaa aagacgtgat tacctcaaaa aacccgcgca
     5281 tcgtggagca aaagacaggg aaaacacgca ttttatactt aagcagctta caggacttga
     5341 ttcacggcta taccgcaccc ttagatccgg aggcttactt gtttcccagt actaagggcg
     5401 gccatttaga agtcaatacg gtctaccaga tgtttcaaaa ggtcgcgaag ctgttaggaa
     5461 gggacgatat cggcacccac accctacgaa aaacctttgg ttaccactat tacaagaaaa
     5521 ccaaagacgt ggccacctta atggaaatct ttggtcacag cagcgagaag attaccaaac
     5581 gctacatcgg aattaatgaa gatgaaatca gtgaaacgtt attaaatttt cggttaggtt
     5641 tttgattgta ttatataata gataagcaca gtaagacggt tataatcacc cacagtattg
     5701 gacaaatcaa cctttttttg gtatattata tatacaaatg agagcaggct catagtcaac
     5761 ttgatataaa tccggaacat aagggtccgg cgggtggcga gcaccaaaac taaactcgat
     5821 acaaatccgg aacgtaaggg tccggcgggt ggcaagcacc aaaactaaac ctgtacaaaa
     5881 ggctgctctt ttgagcagct ttttttattg ggaaaaagga gcattcttcg cacgcggcaa
     5941 aaaaagaata caaacgcatg tctataaaag agacaaccca aattaccaga cagttaaacg
     6001 cgatttataa ggctgctcat ctcttacaag aacattttgt agataaaaaa gtatcctttg
     6061 tcggagaagt ctcaacggta gcgattattt tttcgacaac taattttatg cacctctgtg
     6121 gcattgatta tcgcagaggc acacacttgt tttttcaaga tgccttagac aggaaaataa
     6181 atttacagga tattcaaatc aaaacggatg ggacgacctt tcagaaatta caagtaatag
     6241 gtagccttga tttattattg gggaagcata tttctattgt tggcagaggt gtttactctt
     6301 ctcttcgcta tgatgcagct attcgaacaa ggaaaaaaat attggctctg tctttgaaac
     6361 aaaacggatt aatctatatc cctatctctt tgttaaacct atcatcaaag gaaattggac
     6421 ctggacaaaa agttactggc atttttagcg aggatttaac atccggggaa cttaaaatga
     6481 ttatggaagt catcgattaa tcattaatag tgatatgcga cgtcattttg aagtaattat
     6541 tctattttgg gttataaaat aaagcatttt aagacgattt caaatcattc atgtgggtta
     6601 tt
//
LOCUS       DAYYEF010000094         6537 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000094 DAYYEF010000000
VERSION     DAYYEF010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.098"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            151..531
                     /locus_tag="ACHA1B_002678"
     CDS             151..531
                     /locus_tag="ACHA1B_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFM8703393.1"
                     /translation="MSEQNQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            513..1427
                     /locus_tag="ACHA1B_002679"
     CDS             513..1427
                     /locus_tag="ACHA1B_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFM8703394.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            1387..1665
                     /locus_tag="ACHA1B_002680"
     CDS             1387..1665
                     /locus_tag="ACHA1B_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703395.1"
                     /translation="MKEEQTTNKNYRSKTLKDIENEIKKQRAFLVPYTQERIQTTIDL
                     QVKKLHQELLDQRNKEQKKVLIQRSLDFLAPLCCLVLTLFAFWLVWGG"
     gene            1667..2356
                     /locus_tag="ACHA1B_002681"
     CDS             1667..2356
                     /locus_tag="ACHA1B_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703396.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQVLAQKIEKFTA
                     CYEDMNDIFVKQEKRLTDKNMETLTRLYRNLPEEQQKEYQEKYEQVKKDVQYVKDTKV
                     EEACSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQAINIQNLTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(2476..2562)
                     /locus_tag="ACHA1B_002682"
     CDS             complement(2476..2562)
                     /locus_tag="ACHA1B_002682"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFM8703397.1"
                     /translation="MFELFICPLLVGVCISVFSYWLNNRNKK"
     gene            3208..4140
                     /locus_tag="ACHA1B_002683"
     CDS             3208..4140
                     /locus_tag="ACHA1B_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFM8703398.1"
                     /translation="MANEIVKYEPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFSQLKDLSAYKQTAGEVFIKDLARTYDHLMDLRFGRKSNGGLTIERFTMFTDFEIH
                     GEVDNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRIKLFNIEHNGELTQKEKWRAKDRILNLPLGTHEAD
                     FKKQQQTEKEEAEKQSISNELKQDLLENLQNLFD"
     gene            4157..4627
                     /locus_tag="ACHA1B_002684"
     CDS             4157..4627
                     /locus_tag="ACHA1B_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFM8703399.1"
                     /translation="MIDKTIKELAEEFHVSKQAIRKRLSADFRENYVQTVTRNGVKTL
                     VVSYKGYLLLKQHFLGSNTTGNQVETVASNDENSIIVFLHEQLQEKDTQIKQMQKLLD
                     QQQQLTLQANQQIEKLQEQLQLAYTEEPEEEELTSVNKENNNAITTEKKWWKFW"
     gene            4711..5163
                     /locus_tag="ACHA1B_002685"
     CDS             4711..5163
                     /locus_tag="ACHA1B_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8703400.1"
                     /translation="MTISKVIKQKRIEKQLTQEDLAEMLLVSKKTISNWENGRTIPDT
                     ENLIQFAKLFDLSLDNILLGEEKIMVKNHTKTLILLFHFVIFLSLVFTLIQSGFFYFS
                     HSIATWLLIFFLSLLLIINTLIIIFNKHRNLFLHSIFPIVLLIFLYFI"
     gene            5290..6471
                     /locus_tag="ACHA1B_002686"
     CDS             5290..6471
                     /locus_tag="ACHA1B_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HFM8703401.1"
                     /translation="MKNNRIYKNQLNYGLLLPVFLLCIIGLLSLYVALYHDSYTNSKI
                     TKELIKQVLWYSIGFTSAITIYFFNPKILWKLTPIFYGLCIIMLLLLLKFYNPQLAVL
                     TGAKNWFYIAGFSFQPTELVKIGYTLMLAKITVNYQQKSITSNTKDDWIYLLKTFIAT
                     LPIGILLFFQNDLGTMLVFIVIYIFILFTSNINIKIIAPIIAIGVVLSLIFLYLVISD
                     TGRDFLLKIGFHDYQFKRIDSWLNPFLDPNGSSYQLANSLIAIGSGGLLGTGFNVSNI
                     HVPVRESDMIFSVIGENFGFIGSCLVIFLYFYLIYQMYKTCFKSNNLFFTYIGIGIVA
                     MIFFHVFENIGASIGLLPLTGIPLPYISQGGSAILSNFLGLGFMLCCSRYTNEKKGTQ
                     K"
BASE COUNT         2408 a         1056 c         1108 g         1965 t
ORIGIN      
        1 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaaac
       61 ccttttagtg agctttactc attgtacctt tttaggtaca atggtattgc gaacgatacg
      121 tccgtaggac gtactgaaag ggtgggactt atgagcgaac aaaatcaaaa tttggctagc
      181 gatcattcta aaaaatatac ctatcgatcc gagccaaaac aaatcagttt tcgagtgagc
      241 gaatctgaat ttgcaaagct gaagcagtca gctgaagctt tgcaaatgag tgtgccggct
      301 ttcgtaaaag ccaaggcaca aaacgcgcgt ctggtgacac cgaaagtggc gccagacatt
      361 gcccaggcaa tcgcgcgcga tttagccaaa gctggaggga atatcaatca aattgctaag
      421 tggtgtaata cacaccaaca cgacgttgct cctggagacg cccaacgctt atccgaaaac
      481 ctaaaaatca tgcaaaagga gctacaaaag atatggcaac agttaaagta agccgaacca
      541 cttcttgtag tcgtgcaatt aattacgctg aaccacgagc aaccattaaa acaggaataa
      601 actgtgacgt cgattatgcc aaaagtgaaa tgaaacaaat tcgcatgctg tatggaaaag
      661 acgaccgtgt acaggcacac ttattgattc aatcttttcg accaggagaa attaccgctg
      721 aaaaagctaa tcaactaggg gcagagtatg caaaaaaaat agcccccgat caccaaatag
      781 ctatttacac acatacagac aaagaccata ttcataatca cattgtcatt aactccgtta
      841 atctggagac tggaaaaaaa tttcaagctc atggtcaagc atttctaaac aaatgttatg
      901 acctaaatga cgagatttgt cttgcacata acttaccaat cactgagcga ggaaagaaac
      961 cagaaaaacg aaccatgtct gaaataaaat taaaagaaaa aaatgaacct gtttggaaag
     1021 acgaaattcg gattgcgatc gatcaaacaa tgaaaaacaa aaaaaccaga acctatgacc
     1081 aattttgtaa ttccctcaaa acattgggga ttcattgctt caatcgcggg aaaaatttca
     1141 cttacgaatt gatccacaaa aagaaaaaag tacgatccaa cagactagga aaggactacg
     1201 aaaaggagac gattttacat gagctggaca gacgagaacg aacctataac caacagcgaa
     1261 ccaacgagct acgaagagct cgagctagca ttcgcgaaac tgcagaagaa gtacgaagag
     1321 aacaacgaac tcttacgcct gaacaaccgg aaattagacc ggctcgaaga aaccatgaac
     1381 aacacgttga aagaggaaca gaccaccaac aagaattatc gctctaaaac gttaaaagac
     1441 atagaaaacg aaataaagaa acaacgtgct tttctcgttc cttatacgca agaaaggata
     1501 caaactacga ttgatttaca agttaaaaaa ctccatcaag agctattaga ccagcgaaat
     1561 aaggaacaga aaaaggtgct tattcaacga tcattggatt ttcttgcccc cttatgttgc
     1621 ttagtcctga cactgttcgc attttggtta gtatggggag gctaaaatgg cattttattt
     1681 accctatcta ctcatttttg ttagtatttc aggaagtatt tggctcatct ataaaatttt
     1741 tcaaacaaga tattcattaa aaggctctaa aattcgattt aagcgatttt tctttcttgg
     1801 ctgtatattt tccttgataa tcgtttcaag cggcttattc ggcgttttag agggaaataa
     1861 gcgcgtttct agaagtattt tattaggaaa tgtcactcaa aagtatgaat cagcgcgtga
     1921 taaaaagaaa aaagagcaag tattagcaca aaaaatagaa aaatttaccg cttgttatga
     1981 ggacatgaat gatatttttg tgaagcaaga aaagcgtttg acggataaaa atatggaaac
     2041 actcactcga ctttatcgga atttgccaga agaacagcaa aaagagtacc aagaaaaata
     2101 tgaacaagta aaaaaagacg tgcaatatgt gaaagatacg aaagtggaag aagcttgtag
     2161 tgatttattt ggagatacaa ttcctttttc aactagcgaa caagaacgaa aagaacgaca
     2221 acaatcagtc acatatgaac gctatgaaat cttgcttcaa caagcaatta acatacaaaa
     2281 tctgactaaa aaagaaacag ctttaaatta tttaaaaagc gtcaaggaat ggttagatca
     2341 gcaacagcaa aattgaattt gattgaaatt catgttaaac taaacatgca aatgttcaaa
     2401 cattagatac acgaaagccc cagagaggtc ggattctctg gggctttttt taggttgatg
     2461 tcgcctttac tgattttact tcttgtttcg gttattcaac caataactga atacagagat
     2521 acaaactcct acaagaaggg ggcaaataaa cagttcaaac atcagataca cctccttcca
     2581 gtcgcaagac tgtcggatag gcgacaagtt attataccct acaaaattaa atctgtgtgg
     2641 caattttaag tatctcttat ttccgggttg ttagggcttg ccctgaccgc ctgtagggcg
     2701 ctttaaatgc cagataaagg tttttatact aagactgtct taaaacggct tagacaagct
     2761 cttagagcct caaccctcct ttttgaacaa tggttttagc aaaggagctg gaggcgactg
     2821 cgcaggtata atgtgagagc gtagcgatca cacctttttg gcgaccgtag ggagcgaggt
     2881 tttgaattag cagtttagaa aagttcgcga acctgtttaa agaaaaaata attgtttttt
     2941 taggtgggaa attttgtctc cctcttttat aatctttttt taaacctctt tttaaacctc
     3001 tttaccgtcg gctgtgtcct tactccccca agggatacaa aattttatag gcatgaaatt
     3061 atctgtttat aggcatgaaa ttatctgttt ataggcatga aattatctgt ttataggcat
     3121 gaaattatct gttttaggta ttgtttttag acataatatg tcctaaaatg atgtcaataa
     3181 aatcatttag actggagtaa caactaaatg gcaaatgaaa tcgtaaagta tgaaccagaa
     3241 ttaaatacca ttcctttaag aaaatttacc ccaatagaaa tgaacttgtt tttttctatt
     3301 gtctctagaa tgcgcgataa aggtaatcaa aaaatacgct tttatttcag ccaacttaaa
     3361 gatttaagtg cgtataagca gactgcagga gaagtcttta taaaagattt ggcaagaaca
     3421 tacgatcatt tgatggattt acgtttcgga agaaaaagca atggtggatt aacaatagaa
     3481 cgatttacaa tgtttactga ttttgaaatt catggagaag tcgataaccc ttatgtagat
     3541 ataaaagtcc acgaaaaagc tttgccttta cttaataatc tagaaagctg ggtacgtttc
     3601 tctttaacag aatttcgaga tttaaatagc agttatgcta aaacaatgtt tagattgcta
     3661 aaacaatacc gaactcaagg atgggctgaa ttttctaagg aagatttttt agagctatta
     3721 gatattccta aaagctatag acaaacaaat ataaatcagt ttgtactcaa accaataaaa
     3781 gaagaactaa ctccactatt taaaggatta actattcgta aaaaatatgg taaaggtcga
     3841 ggtaaacctg ttattggtta tcgttttact tggaaagctg aaatcaacca tgctgacgat
     3901 ttttcaaaag ggaagcaaga agatttacgt ataaaattat ttaatattga acacaatgga
     3961 gaattaacac aaaaagaaaa atggcgtgct aaagatcgaa tactaaatct tccgttaggt
     4021 actcatgaag ctgattttaa aaaacaacaa caaaccgaaa aagaagaagc ggaaaaacaa
     4081 tcaatctcaa atgagcttaa acaagattta ttagaaaact tacaaaactt attcgattga
     4141 agcataagga gtatttatga tagataaaac gatcaaagaa ctcgcggaag aatttcatgt
     4201 ttcaaaacaa gcaattagga aaaggctatc agctgatttt agagaaaact atgtgcaaac
     4261 tgttactagg aacggagtga aaaccttagt tgtcagctac aaaggatatt tgcttttaaa
     4321 acaacatttt ttaggtagta acaccactgg taaccaagta gaaaccgttg ctagtaacga
     4381 tgaaaactcg attattgttt ttttacatga acagctccaa gaaaaagata ctcaaataaa
     4441 acaaatgcaa aagttactcg accagcaaca acaactcacc ttgcaggcaa atcaacagat
     4501 cgaaaaactg caagaacagt tacaattagc ttatacggaa gaacctgaag aagaggaatt
     4561 aacttctgtc aataaagaaa acaacaatgc aataacaaca gaaaaaaagt ggtggaaatt
     4621 ttggtaacaa ttaccaactt tccataaaga agaaatcaat ttctatagac tctatctttc
     4681 taagaataaa aaatatgttt aggtgatcaa atgactataa gtaaagtaat caaacaaaaa
     4741 agaatagaaa aacaactaac tcaagaagat ttagctgaaa tgcttttagt atctaaaaaa
     4801 accatttcta attgggaaaa tggtcgaaca ataccagata cagaaaattt aattcagttt
     4861 gctaagttat ttgatttatc actagacaat attttgttag gagaagaaaa aattatggta
     4921 aaaaatcata caaaaacact aatactatta tttcattttg taattttttt aagtttagtt
     4981 ttcaccttaa ttcagtccgg attcttttat tttagccatt caattgccac ttggttatta
     5041 atattttttc taagtttact attaataatt aatactttaa ttattatctt taataaacat
     5101 agaaacttat ttcttcacag catatttcca attgttttat taatttttct atactttata
     5161 taaaaagata gaactattta gtaagataaa aaagtagcta attgtaattt tcgtctaaaa
     5221 ctcaaaacta gtaaaaataa ctttattgtg ttatttttat ttataaatta tgaaaaagga
     5281 cctttcgaaa tgaaaaataa tagaatctac aaaaatcagt tgaattatgg gcttttattg
     5341 ccagtttttc tgctatgtat cattggatta ctttctttat atgttgcttt atatcacgac
     5401 tcttacacta attcaaaaat cacaaaagaa ttaattaaac aagtattgtg gtatagtatt
     5461 gggttcactt cagcaataac tatttatttt tttaatccta aaattttgtg gaaattaact
     5521 cctatatttt acggattatg catcataatg ttattacttc tcttgaaatt ctataatcca
     5581 caattagcag tcttaactgg agcaaaaaat tggttttata ttgctggttt ttcgtttcaa
     5641 cctactgagt tagtcaaaat aggatacacc cttatgctag ctaaaataac cgtcaattat
     5701 cagcaaaaat ctattactag taatacgaaa gatgattgga tttatttact taaaactttt
     5761 attgctactc ttccaatagg aatattatta ttttttcaga acgatctagg aacaatgtta
     5821 gtcttcattg ttatttatat ttttattttg tttacgtcta acataaatat aaaaataatt
     5881 gccccaataa tcgccattgg tgttgtttta tccttaatat ttttatattt ggttatatca
     5941 gatacaggaa gagatttctt attaaaaata ggatttcacg actatcagtt taaaagaata
     6001 gactcatggt tgaatccatt tttagatcca aatggatcta gctatcagtt agcaaatagt
     6061 ttaattgcta ttggctctgg cggactttta ggtactggtt ttaatgtatc aaacattcac
     6121 gttcctgtta gagaatccga tatgatattt tctgtaattg gagaaaattt tggctttata
     6181 ggaagttgtc ttgtaatatt cctatacttt tatttaattt atcaaatgta taaaacatgt
     6241 tttaaaagca ataacttatt tttcacctat atcggtatag gcattgttgc aatgattttt
     6301 tttcatgttt ttgaaaatat aggtgcaagt atcggattac tacctctaac tggtattcca
     6361 ctcccctata ttagtcaagg tggttctgcc attcttagta attttttggg gttgggattt
     6421 atgttgtgtt gtagtagata tactaacgaa aaaaaaggaa cacaaaaatg aattcaaaat
     6481 aacactttat gaatagaatg tctatttcaa taaaaattat gataccttaa agttaat
//
LOCUS       DAYYEF010000095         6516 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000095 DAYYEF010000000
VERSION     DAYYEF010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.099"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(53..826)
                     /locus_tag="ACHA1B_002687"
                     /pseudo
     CDS             complement(53..826)
                     /locus_tag="ACHA1B_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            862..2049
                     /locus_tag="ACHA1B_002688"
     CDS             862..2049
                     /locus_tag="ACHA1B_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HFM8703402.1"
                     /translation="MQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNTLYLDK
                     SLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAKGLFVE
                     KLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYESAMIQ
                     GFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDYQLPEG
                     SRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEMILNDV
                     NNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTEVNINE
                     YSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVTEYIKN
                     YFN"
     gene            2782..3750
                     /locus_tag="ACHA1B_002689"
     CDS             2782..3750
                     /locus_tag="ACHA1B_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFM8703403.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            3761..4576
                     /locus_tag="ACHA1B_002690"
     CDS             3761..4576
                     /locus_tag="ACHA1B_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HFM8703404.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            4644..5354
                     /locus_tag="ACHA1B_002691"
     CDS             4644..5354
                     /locus_tag="ACHA1B_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM8703405.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            5390..>6516
                     /locus_tag="ACHA1B_002692"
     CDS             5390..>6516
                     /locus_tag="ACHA1B_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFM8703406.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIK"
BASE COUNT         2196 a         1001 c         1329 g         1990 t
ORIGIN      
        1 gccaataaaa cttagtccga tatgcggcgc gttctgtgcg ccgcatattt ttttagtttt
       61 caaagatcag accttgttgt aaatagatcc gtgcccgaaa gttataaaag ttgcgataac
      121 caaacgcaat tcgtttaatc agcttgatct tgttatacag cccctcagtg acgccgtttg
      181 agtgggacac cttaaaggca tttgaaatac ccgattggta gcgatggaag atcgtgaatt
      241 tctttttaaa cgactgaggt aacgtagatg aaattgtttt aagggtttct tgaaagccta
      301 ccgtatctcg tttaacgaaa taatagcgta ataattgaca aaaatgatac gcagttcgca
      361 attcttcgtt gtagcttaac agctcattaa cgatttctgt ttgactaatt ggtcgtttaa
      421 acagtcgatg ataatgccgt ttgagtgcct cccatgtcgt ggaatctttg agtaagagtt
      481 tccaatatcg cttgagccga cggtacttct tctgattttc agagtgtgag gttcgaaaac
      541 gattcatgat ctggacacgt aattgattga agctgcgatt gatgtgttgg acaatatgaa
      601 agcggtcagt tacgatctcc gcatttggaa agaccgtttt aagcaactga caatagctgg
      661 cattcatgtc catcactagg tacttgacct ttaaacgggc ctttctagga aagcgcagga
      721 agtattgagt tagtttgtaa agtctgcgat cttcaagggt cgtaaatagc tgattggttg
      781 tcccatcaac acaaataaaa ctcatggaac cagaagtggc aacattgtgt acttttcttt
      841 gcaatcttgt gtacaaaact attgcaaaac acagcgcata agaatcctta caaaacagta
      901 gatgaagcaa cccaattaga tcttgttata gttgttaatc agctcttaac gggttacgat
      961 tcaaaatggg tcaacaccct atacttagat aagtcacttg aatatcagaa cataattcag
     1021 gctttttcac gcacaaatcg tcttaatggt cctgaaaaac cgttcggaac cattcgttat
     1081 tatcgtaaag cacatacgat ggaacagaac attgaagagg ctattgagtt atactcaggc
     1141 aaacaagcaa aagggttatt tgttgaaaaa ttatataata acttagaaaa gttgaacgat
     1201 atattcgaag aaattaagtc cgtatttaat atttctggca tagaaaactt cagtcattta
     1261 ccggaggttc caggggaaat taagcaattt gtaaatcttt ataatcaact aatccattgt
     1321 tatgaatcag cgatgataca gggattcaca tgggcaaaat cgacttatga aatccaggat
     1381 tatgaaccta taacagtagt aatcacagaa tatgaattta atatcttggc acaacgttac
     1441 agcgagatag agagagaacc tagagacgga aatgatagta tagcgtatga cattgattac
     1501 caattacctg aaggtagtcg tagtcgtatt aattatgagt atttaaacac aaacttcaaa
     1561 aaatacatga atataaaaga agaacgtgat tcgaatttaa ttcaatcatt gttaaacgac
     1621 ttacatcgca catttgcgca attaccagtg gagttacagc catatgctga gatgattcta
     1681 aatgatgtaa ataatgggga attagttatc aaagaaggat gggaatttac tgattacctc
     1741 aatgaatatc agcttagtga agaggacgat tttatccaag atttagtgga ttcaaccaat
     1801 attaatgagg cattattacg tgagatgttg gatttacgct taaccgaggt aaacattaat
     1861 gaatatagtc gatttgataa attaaaatca agtgttaacg taggtcattt cagtggatat
     1921 atcgagaaaa atttaggtaa aatggtaata ccaatcaagg taaatatgct aattgacaga
     1981 ttattgcgtg catttttatt agaagatgta ttcgatgtta cagagtacat aaagaattac
     2041 tttaactaga gtacacctac atcttatagt acataaaaaa attcatcttt tttagtttaa
     2101 taattcacca aaaaggtgag taatgccatt tttgaaaatt gagcttgttt tatgtctaca
     2161 tctgtatccg tatataatcc aaaggattat aaactcagaa gagtctttat tttttctgaa
     2221 tataactact gtatcaaaaa caatcgatta tgagacaaaa caaaatgacc tcttttattt
     2281 aagaaaggag gtcatttttt gtatcataaa ttgtattaaa atcaatgtat cactttttaa
     2341 tcaattttaa gaccataaat tgcgtactaa aagaaattct gcaattcaaa ataaagcatt
     2401 ttaagccatt ttcaaattta agtgcaccca tctacccgtc aaatcacttt attttccact
     2461 ccagtagttt cctaattcaa ctgtgtgcaa aacgatttct tctaaacaaa tcaagacaaa
     2521 cttataaacc ttcatcccag caccataatt atttaaatca taggcatttt tcgaaattag
     2581 tatatgtact caagtttcac tgcagattat ttatattttt tagagaaata aatttttcct
     2641 attgacaaac acaaagaaag cggatacaat acaattatgt cacatgacgt tatatgacgt
     2701 tatgtaatat ctttacattt aatcagttac ttttattttg gataaaatta acatttttaa
     2761 aattttaagg aggaaatgtt gatggatgta gcaaaaacgg ttaacgcaat tgtagaaaaa
     2821 aatgatggag agatttctgg aatttatttg gtggcttgtg gcggttcgct ggtagatatg
     2881 tatgtctcag attattttct taaagccgaa gcatcgaagt gtattacagg cttatataca
     2941 gcgaacgaat ttaaccatgt aaccccaaag caattagatg ataaatctgt tgtcattcta
     3001 tgttctcatg gaggaaatac agcagaaacg gtaaaagcag gagaagtcgc tcaagctaga
     3061 ggagctgtga ctgttggtct gactcataat aaaactgcgg atttattaaa ggtttctgat
     3121 catagtttcc tttacgaatg gggagatgat gcaaaaatag tcaataatcc tatggccatc
     3181 attcttgatt taactgtatc tttggtcaat gttaccgaaa catttgaaca ttacggtaaa
     3241 ttcagagaag gcatgaaggt tatcgatacc gtaattgaaa atggcattaa gcaggtgcag
     3301 gatcgtatta aagtgtttgc tgataagtac aaagatgaaa caatgtttta tatcttaggt
     3361 agtggaccat catatggaca tgcttatggt ttttcaattt gctctttgat ggaaatgcaa
     3421 tggcttgatt caacttctgt tcattctgga gaattcttcc atggaccttt tgaagtaaca
     3481 gacaaagata cgaattttat tctcttgatg agcattggac gcactcgtgc tttagatgaa
     3541 cgggcaaaac gattccttga taaatatgca gaaagagtag aaatcgttga tgcaaaggaa
     3601 ctaggattgg atatgatatc agatgaagtt tctgaattct tcaatcccat tttattctac
     3661 agtattcttt cagaatatcg ttcagcttta gcagatgcac gcaatcatga tttagatgtt
     3721 cgtcgctata tggggaaagt ggagtactag gaggattaaa atgaaggtat taggcttagg
     3781 tgataacgtc gtcgataaat atgaaaatct gggaattatg tatcctggag gaaattcatt
     3841 gaattttgca gtttttgcaa aaaaactggg acatgaaagt agctttatgg gagtttttgg
     3901 ctcagatgag gaggcagctc atgttttatc agcaataaaa aaaataggac tggacaacag
     3961 tcactctcgc tttgaaaaag gcgagaatgg ctgtgccaga gtgaagattg atgagggcga
     4021 ccggattttc cttggcagca attcgggagg tgttactcgt gaatacccga ttcagcttac
     4081 tgaagaagac agagaatatt taaaccagtt tgaattgatt catatgggat tatatagcca
     4141 tgtcaatcat ctattagaag agttacaaaa tgtttctgga aagatttctt atgatttttc
     4201 tgacgacttt acggaagaag aggttcagcg ggcaattgat aaagttgatt ttggcttctt
     4261 ttctatagaa gacttttccg atgaagaagt aaagcagttt ttgatgaagc atttttgtga
     4321 gcgaaatgat gtattgattg caacccgagg agaaaaaacg gctattggtt atgatggagc
     4381 aaagttttat gaagtgaacc ccgtgctaga agaaccagtt gatacaatgg cagcgggaga
     4441 ttctttctta acagctttcc tactttattt tctcgaaggg gacgatatag tcaccgcgat
     4501 gaaaaagggg aatgaatttg ctgggaagtc ttgtctggtt gacggttcgt tcggctttgg
     4561 tattcattac gattgagctt gttttaaatt cctgcatttg ataacctaaa gaaagaaatc
     4621 ccggtaaagt ggaggttaaa aaaatgctgg atacaaatgc acaattacca ttgtacttac
     4681 aattaaaaga aatattaaaa aataaaatca atacagggga gtatcccgag aatacgaaaa
     4741 ttcccgctga atcagagctg atagaaagtt atgaggtcag ccgaatcaca gtgagaaaag
     4801 cagtagaaga actggtagaa gaagggtacc tacttaaaaa acaagggaaa ggaacttttg
     4861 tcaaccggca taaagttttt cgtaaaattg aatatgttat gggtttcagt gagagttgta
     4921 aatctaatgg ttttacaccg actagcattg ttttggaacg caagatcatt ccagcaactg
     4981 aagggatggc aaaaaaactc gatatcgctc aaggtgatga tgttttatat atccagagaa
     5041 agcgaatggc ggataacatc cccattatgt tagaaaacaa ttatttttct tatgaaagat
     5101 atagtttctt aatggaggaa gagctgactg attctttgta tgaagtactt aaagtccaag
     5161 gtaccttagc catcaatcct ggggaaactg cacttgaaat tgtcacagct gatgaccaaa
     5221 ttgccaaaat aatggaagta gctgttggga cgcccttttt ctttatggat actttaatca
     5281 acgatcaaaa caacatacca attcatgtag gtaatcaata ttacctggga gaagtatatc
     5341 gtttttactt atgatttcct gttttgattt caaggagtag attttattta tgaagcaagt
     5401 attgcggtca aaaatgattt ttgatggaga gcagccacct ttcaaaggtt atattgtaat
     5461 caatgaaggg atcattgaaa aggtggaaaa caactggaat tacagtgatc tattaaatga
     5521 aaacacggaa ttaattgctt atgatgatca attcgttatg ccagcaattc atgataatca
     5581 tgtatttttc agtggttatt tggctatgaa tgctggcata gatttaagcg atacatcttc
     5641 agctaacgag gctgtagagc gtattaaagc tgtaatgaac cataaaaaag cagatgaacc
     5701 aatttatgct catggctggg atgctgccct gtggaaaact gacccatcag aagagctatt
     5761 gaatgaaata aaccactttg gtccaatcac agcgatcgac aaaaatcgca gccattgttg
     5821 gatgaatgct attgctaagc agacttatgg ttttacagaa aaagaaacca gtgctgaaag
     5881 tcgagtatta ttaattaagg aaatgctagc aaacaaaaag cttttagcag aggtttacgc
     5941 tgaatttgaa gcattactgc tttcaaaagg tgttatatca atgaaagaaa tcgtttttga
     6001 tgacgcagaa tttctttcta atatacctca gaggaaaata cttagtaacc tatatgtgca
     6061 ggcagtccaa gaacctctac agcatgaact tctatatgag tataaggaaa aagttttccc
     6121 tgaaaaggtc cgctttggtg gagtgaagat catggtagat ggtgttgttg cggatagaag
     6181 tggagatatt tacggtgttt atcagtcagg agtagcttca cccgagattg actatgaggc
     6241 aattaaagca gaagttgctg cattcaatga agtagagatt ccttgctgtt tgacaacgga
     6301 aggagataaa gcgggttata aagctgcgtc aattcttgtc gaatttggaa agcggttacc
     6361 tgaaggcgtt tttaattcga ttagtgattt ggaaatggtt actcaaaaga cagcagaaaa
     6421 aatgaacgaa ggacaagtag tagcagaggt atatccacaa attctcggct tgaatcaaac
     6481 gttagaagag gcttacatgt caactgttat aaaaaa
//
LOCUS       DAYYEF010000096         6173 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000096 DAYYEF010000000
VERSION     DAYYEF010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.100"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            725..811
                     /locus_tag="ACHA1B_002693"
     CDS             725..811
                     /locus_tag="ACHA1B_002693"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFM8703407.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="ACHA1B_002694"
     CDS             complement(932..1621)
                     /locus_tag="ACHA1B_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703408.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1628..1906)
                     /locus_tag="ACHA1B_002695"
     CDS             complement(1628..1906)
                     /locus_tag="ACHA1B_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703409.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1866..2780)
                     /locus_tag="ACHA1B_002696"
     CDS             complement(1866..2780)
                     /locus_tag="ACHA1B_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFM8703410.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="ACHA1B_002697"
     CDS             complement(2762..3142)
                     /locus_tag="ACHA1B_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HFM8703411.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="ACHA1B_002698"
     CDS             complement(3592..3879)
                     /locus_tag="ACHA1B_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HFM8703412.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="ACHA1B_002699"
     CDS             complement(3899..4123)
                     /locus_tag="ACHA1B_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HFM8703413.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="ACHA1B_002700"
     CDS             complement(4578..4748)
                     /locus_tag="ACHA1B_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703414.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="ACHA1B_002701"
     CDS             complement(4763..5296)
                     /locus_tag="ACHA1B_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFM8703415.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..>6173)
                     /locus_tag="ACHA1B_002702"
     CDS             complement(5317..>6173)
                     /locus_tag="ACHA1B_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HFM8703416.1"
                     /translation="IVSRMREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEK
                     ILSLRFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYS
                     LQQFNELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPI
                     RQELTAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALAL
                     ADKQKEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLL
                     SDLDNLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAYYEF010000097         6065 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000097 DAYYEF010000000
VERSION     DAYYEF010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6065
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.101"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            832..1566
                     /locus_tag="ACHA1B_002703"
     CDS             832..1566
                     /locus_tag="ACHA1B_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HFM8703417.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1582..2751
                     /locus_tag="ACHA1B_002704"
     CDS             1582..2751
                     /locus_tag="ACHA1B_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA];
                     GO_process: GO:1901135 - carbohydrate derivative metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HFM8703418.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2767..3762
                     /gene="lacD"
                     /locus_tag="ACHA1B_002705"
     CDS             2767..3762
                     /gene="lacD"
                     /locus_tag="ACHA1B_002705"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0009025 - tagatose-bisphosphate aldolase
                     activity [Evidence IEA];
                     GO_process: GO:0019512 - lactose catabolic process via
                     tagatose-6-phosphate [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HFM8703419.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3841..4767
                     /locus_tag="ACHA1B_002706"
     CDS             3841..4767
                     /locus_tag="ACHA1B_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HFM8703420.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4786..6036
                     /locus_tag="ACHA1B_002707"
     CDS             4786..6036
                     /locus_tag="ACHA1B_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HFM8703421.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         2025 a          997 c         1246 g         1797 t
ORIGIN      
        1 attggcgcag cgaatccttg ataatgagct cggatgtgct aacgctagcg aggcagtcta
       61 actttaactg ttagctcctg ccgaagatcg tcacatccga ggaggctcat tgtcaaggac
      121 aatcggaata gcatacggaa agaagttctg caccttataa aatttgtcaa aaaaactgtt
      181 gccattccaa agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt
      241 gactaaacga agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat
      301 tcagataaac tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc
      361 ttaagagaga acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat
      421 ttattctcat agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga
      481 tttgaaacca aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca
      541 ctggtaagta gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta
      601 aaaaaagata ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa
      661 aagttggaaa attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat
      721 attaacaaga ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa
      781 ataccactac tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat
      841 acctttcaat caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa
      901 aacagtatgg tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc
      961 gttagtcgca cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat
     1021 cgacaacatg gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct
     1081 ggcgcatata gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata
     1141 ttggccttca agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta
     1201 ggtgagcctt tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc
     1261 gagaaatcct atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg
     1321 aaacctttat ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag
     1381 gaattttatg ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga
     1441 tcaccagtgc tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt
     1501 acattaagtg tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact
     1561 aactgaattg gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga
     1621 gcagaaaata ctacccgaga aattcgacag caaccggaac tgtggcatga gacgtttgac
     1681 cgttatcaag aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct
     1741 ggagagcgac caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat
     1801 acactaattc cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt
     1861 ggttcgaccg atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc
     1921 ttggtctcat ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc
     1981 aatcagctgg tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg
     2041 gctacacaaa tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat
     2101 gacgctggtt ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt
     2161 tttgatcaag caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga
     2221 gaagaagtca tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc
     2281 atcatttact taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt
     2341 ctcgagttaa ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat
     2401 ggtcccaaat cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca
     2461 tatacgcaga aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa
     2521 cgcgttgttg gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt
     2581 gcagattcgt tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg
     2641 atcgcattac tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga
     2701 acagtcaatc gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg
     2761 tgaagcatgt tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca
     2821 gaaggcatta ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg
     2881 gctttaggga tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa
     2941 gaattgactc cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca
     3001 cagaagcgtg cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa
     3061 accgtacccg gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag
     3121 ttaggtgcgg atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc
     3181 aatcggcaaa agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg
     3241 ccattttatt tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc
     3301 tatgccaaag caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag
     3361 tataaagtag atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat
     3421 gcaacagggg agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc
     3481 gatgcaacag atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg
     3541 gagacattgc gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga
     3601 gcaacttgga aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa
     3661 tggctgacag aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact
     3721 gccatcccat ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt
     3781 agtgataaga gatatgtgtg attataattt atcattattg aaactgggag gatattttat
     3841 atgaataaaa gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa
     3901 ttaaagcagg caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt
     3961 agctgtcctt acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct
     4021 gatttaattt tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta
     4081 actctaaaag agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta
     4141 aatttagaac ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt
     4201 ggtagaatcg tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt
     4261 tgtttaactg gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca
     4321 ttatccaaat caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt
     4381 gatgaaccaa ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt
     4441 ttattagttc ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc
     4501 gttgattata taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta
     4561 acggctaatg gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta
     4621 gcatcaaaag catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt
     4681 cttccagaaa atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt
     4741 atgttaggaa aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt
     4801 caaaaaatag ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg
     4861 gctgcagtta tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg
     4921 atagaaggat ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca
     4981 tcagattcaa catttggtat tattggatta gctgttacct actctttggg acacaatcta
     5041 gcaaagactt atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt
     5101 ttacttacac ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt
     5161 acctcgggtc tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg
     5221 tttgtactta aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga
     5281 gctttcgttg ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta
     5341 atttgttata aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa
     5401 ccactatctt tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt
     5461 ttcttttgga tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta
     5521 ttattgcaaa actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac
     5581 attataactt atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt
     5641 gcacttgcca ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag
     5701 ttatcaatcg ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact
     5761 atattaaata taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt
     5821 acttattttt caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg
     5881 acaactccac cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg
     5941 attcaagtaa taacaattgc aataaatgtt ttgatatact atccattctt taaattagat
     6001 gataatgcca agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt
     6061 agtta
//
LOCUS       DAYYEF010000098         5769 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000098 DAYYEF010000000
VERSION     DAYYEF010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.103"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..300)
                     /locus_tag="ACHA1B_002708"
     CDS             complement(<1..300)
                     /locus_tag="ACHA1B_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
                     /protein_id="HFM8703422.1"
                     /translation="MNKHNRKITNNKELILLLIGIWGIFLLFNMYMPTMRADDVVYAS
                     RLDELGYLGASIEHYKTWSSRIIIELFLMFFSKHFMLWKLLNSTIMLGIVVLLCKY"
     gene            393..742
                     /locus_tag="ACHA1B_002709"
                     /pseudo
     CDS             393..742
                     /locus_tag="ACHA1B_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(1014..1304)
                     /locus_tag="ACHA1B_002710"
     CDS             complement(1014..1304)
                     /locus_tag="ACHA1B_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703423.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1706..1942
                     /locus_tag="ACHA1B_002711"
     CDS             1706..1942
                     /locus_tag="ACHA1B_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703424.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1949..3901
                     /locus_tag="ACHA1B_002712"
     CDS             1949..3901
                     /locus_tag="ACHA1B_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFM8703425.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="ACHA1B_002713"
     CDS             complement(3973..4470)
                     /gene="dfrG"
                     /locus_tag="ACHA1B_002713"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFM8703426.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(4797..5489)
                     /locus_tag="ACHA1B_002714"
     CDS             complement(4797..5489)
                     /locus_tag="ACHA1B_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFM8703427.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT         1894 a          996 c          917 g         1962 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattta agtagttcag ttttggagta caaaaagtga
     1501 aaatgtaaac ctaaatgagt atcaaattgc aactgaattt gatactcgtt ttttattgtt
     1561 aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag ttaaaatgta tataaaaatg
     1621 cgaacgtgaa ataattattg taggaatgca aattggtgtg ttaaaatggt tacaatttac
     1681 taagcaaaaa ggggtgcatt ttcctatgca atttcttgag ccaaaaaata agaacgctaa
     1741 gtctgtggat tgggaaatat cagagcaagt aagggtgata gttaagcaat acgctgaata
     1801 tgcagagcgt actgaaagcg aagcagtgga tgaattctta ttgaacattt tagacgataa
     1861 gaagtttatt gaatggattg ccaacaagcg aagtaataag cggattgttg aaaaaatggg
     1921 tatcaaagat agagtgggtt gatagacaat gaccaagctt aaaagattag ccacgaagga
     1981 agatgaaatt gtagatgtta aaattccgat ttcaaacgaa gaattaaaag atagggctaa
     2041 acaatatgat ttattaactc caaaacgatt tgcaacaagg tataacaaaa tgttgttctt
     2101 gccaacgtct tttaaatgga acggttctga atatcccatt caatataatt actgcatcaa
     2161 tccgttttgt tgtaattttg ggaaagaaca gcacaaattc aaagatgtaa aagggaaacc
     2221 aagtcgatat aaaatgactg gtagttccaa agataaaggt cataaaggta tgtactgcaa
     2281 tgacaatcct attggcagag gtgtatcgca aaactgtaca gtaacccctt tatctaattg
     2341 gtctgttgtt gaagaaatta aacgccttat agaaatcaat agcatccaag atgttgagcc
     2401 agattatcaa tttcataaag aaggctgctc ggaagaagaa tcaaccccat tcaatgagcc
     2461 gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct caacgctatc aatgtaaggc
     2521 gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa accactactt atcaccaaca
     2581 aaagaacacc attcttccaa tgttcgctaa gatggttgtt ggaagggttt cagtcagtcg
     2641 tacttgtgat attttaggaa ttggagttgg aacctactat cataagctgg agtggctgta
     2701 taggcgttgt ttggagtttt tagaacgata tgagacacaa ccccttcaaa caaagaaatt
     2761 taacgagatg tggcttaata cggacaagat gcactactac ctaaataacg tccgtaagaa
     2821 aggacaaggt tcaaagaaat atacggggtt tgaagacctt aatatgcaaa cgtatatagt
     2881 tgtatctgct gaggtcttat caagatatgt gttccgttct gatgttgcct atgattggaa
     2941 tatttcaatg gatgaattaa atgaagatac aagaaaattc aaagaagacc atctcaatac
     3001 ttttagtcgt aaaaatgata ggttagattg gtcttattat ccacaagaac catccgctaa
     3061 cgatagcgaa aataggaatg cttatcttca cgaattaggg aaaattacta ataggagtag
     3121 atttgtcgat ggtttaaatg ttgatgctcc ttatactaca actgctcact attggttaat
     3181 taaacaaatg gttaatgccg acgaatggcg aatgattagt gatgatgact tctctattag
     3241 aaacgccttt tatagagtat tcacgaaaga attaaggttg agcgatgcac atcattttat
     3301 ttgccaagtt aacaagacga aaagcagaaa acaatgctta aaagaattcg gacaagcaaa
     3361 agcagaactg ctcgattggg gagatatcag aggattcaaa acaaagtttc tacggacttt
     3421 ggcatctcat tatctaactg aattactaac aagtcatcaa ttccacgaag aggctattag
     3481 taaagatgga gaaagatatc gcaaatatgc cgataaccct atcaaacatc cattagccac
     3541 taaggataaa ggattttatt cagttgattg tagaacggat ttatctgctc tggaaccaaa
     3601 cgaaatcgca aagatgctat taaatgttaa tgaccattcg accaatagct ttattcaaca
     3661 gataagacgt tatatatcat ctcttgaaag accattaaca acagctcgtg gtgataagaa
     3721 gagctatatt tacgctaact tcaatccgaa gtatgctcaa tttgcgatta caattctaag
     3781 aacttactac aacttttgtc gcccttttaa atcagcggat aaaaaggttt tgacacctgc
     3841 tcaaagatta gggattacag ataaacaatt tgattggaaa gatataattt atttcaaatg
     3901 acaaaaagag cttggagtaa tcccaagctc ttgtgcttta tctttactgt tcttcttcaa
     3961 ttaacgcacc cgttaactca ataagttttt tctttcatat acatgaaaat agtagttata
     4021 cggattttta tcattcttta tccctttttg ggcaaatacc tcattccatt cctcataatt
     4081 cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt atttttgtga tgtacatttt
     4141 ctcaacataa gggaaaaaca aattataaat ctgttctcct ccgaaaataa aaatttcttc
     4201 ttcgttttta cataactcaa aaacatcttc tattgaatga acaatttcac aaccattaaa
     4261 ggtaaacccc ttatctctcg tcagaataat atttcttctg tcaggtaagg ctcttccgat
     4321 tgattcaagg ttcttcctac ctaatattat cggatgtccc tttgtagtat ttttaacata
     4381 ttcccagtcc ttgggaatcc tccaaggaat gtcattctct ttgccaatca ctctattctt
     4441 atccatcgca gcaatcaaag aaactttcat ttataacaca gcctttttaa ctaatttacc
     4501 atctaatttc ttatttctat caaaaaacct tttctcatta tcctgcccgt tagttgaata
     4561 agcaattttt tctataagtt atattatcat aataccacaa aatcacaaat tttcattcaa
     4621 ttatcatttt caattgcatt ttataaatca ttttgtatgt aatttggtat gtaagttaaa
     4681 atgaaaaaag tagtccattt tgaagtacat tttgtcattt tgtactccaa aactgaacta
     4741 cttagtatag attactgttg cttctttact aatttaggtt tacttgttaa gaaagattat
     4801 ttacgcaaat gttcttcaac aatttgctga gatttatcag ctgtatcttc cacttcatct
     4861 tttgcttttt ctaacttttg aatatattgt ttcaagcttg agttttcagc agttgcttcg
     4921 tctaatttct tttgtgtatc tgttaactga gtttctacat ttgttttttc ttgtgtcagt
     4981 gttgcgattt gttgattcaa accatttaca gtattttgta attctgaaag ttttgcttgt
     5041 gcttcttgta gtcttgctgt ccaatctgca ttcagatgat tgatttcatc atttttttgg
     5101 ttgatctcat ctagtttgac attgatttca ttttgtttgc tttgtagttg tgcatccttg
     5161 ctgactaatt gactttctaa gttttgtttt tctgctgccg attgattttt ttggttttct
     5221 aattcattta cttttgtttg gtattcttgg acatctgcct ttgaatcttg caatgtctgt
     5281 tctttttgtg ctagtcgagc ggtaagatct gtaatcgctt gctctttatc tgtcaatgta
     5341 tgatcaagct gtgtcagatt ctcattgatt gtatcaatat ctgtctctcc accccacaaa
     5401 ataatttcat ttgcgtaccg cgtgcctgtg tagccaatta gacatagaaa tgcaacgaca
     5461 atcccaccag taataaattt ctttttcatt tgcatagctc cttaatccaa tacttttaca
     5521 tgctaaaagt aagtgatctc aaacacaatg tcaagcgttt ttaaattaca tatgtaattt
     5581 taatataaat actatcaaat actcatttaa tcctcctttt ttatctattt aaaaaatctt
     5641 ttttatagag aaaaatgcag gttaatactt tcttaaataa atatttatgg tgaacaaaaa
     5701 caaaaaagca agttttatta aacgtaaccc ttttcatttc atagattact gtatttatta
     5761 caaaaaacg
//
LOCUS       DAYYEF010000099         5727 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000099 DAYYEF010000000
VERSION     DAYYEF010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.104"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            196..921
                     /locus_tag="ACHA1B_002715"
     CDS             196..921
                     /locus_tag="ACHA1B_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703428.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="ACHA1B_002716"
     CDS             911..1420
                     /locus_tag="ACHA1B_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703429.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="ACHA1B_002717"
     CDS             complement(1490..2938)
                     /locus_tag="ACHA1B_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM8703430.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="ACHA1B_002718"
     CDS             complement(2938..3654)
                     /locus_tag="ACHA1B_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HFM8703431.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="ACHA1B_002719"
     CDS             complement(3635..3985)
                     /locus_tag="ACHA1B_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HFM8703432.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="ACHA1B_002720"
     CDS             4129..4902
                     /locus_tag="ACHA1B_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HFM8703433.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="ACHA1B_002721"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="ACHA1B_002721"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         1662 a         1124 c          994 g         1947 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 atcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt tttttta
//
LOCUS       DAYYEF010000100         5672 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000100 DAYYEF010000000
VERSION     DAYYEF010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.105"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            250..675
                     /locus_tag="ACHA1B_002722"
     CDS             250..675
                     /locus_tag="ACHA1B_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM8703434.1"
                     /translation="MHLHRISALAVQIGRYHHSETRAVMEGLEEAIQTTNDCPYRRTF
                     HSDQGWAYQMKAYRNKLKEYKIFQSLSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCF
                     EELKSAIDSYIYYYNNERIKQKLNCQSPVQFRKTTVTVV"
     gene            complement(980..1942)
                     /locus_tag="ACHA1B_002723"
     CDS             complement(980..1942)
                     /locus_tag="ACHA1B_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8703435.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGESI"
     gene            complement(1944..3383)
                     /locus_tag="ACHA1B_002724"
     CDS             complement(1944..3383)
                     /locus_tag="ACHA1B_002724"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004564 - beta-fructofuranosidase activity
                     [Evidence IEA];
                     GO_process: GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HFM8703436.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3568..5514
                     /locus_tag="ACHA1B_002725"
     CDS             3568..5514
                     /locus_tag="ACHA1B_002725"
                     /EC_number="2.7.1.211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-specific PTS transporter subunit IIBC"
                     /protein_id="HFM8703437.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
BASE COUNT         1821 a          977 c          940 g         1934 t
ORIGIN      
        1 tataaataac tcataaaaaa tattttgact ttcaaaatca cttttgctac cagaagttga
       61 ggcgaagtgt tttaagcata gttgtaccct agtttgaccg ttaaaaataa ataacgatcg
      121 ctagagtgca actatgtttg tttgctctac cgtcagcgtc ggcttggcct ctcacatcca
      181 ttaccgtcgg gatcatctcc gttacatacc cttacaaaat acgccctgta agcattgcat
      241 gaaaccaccg tgcatttgca ccgtatttcc gccctagccg ttcaaatcgg tcgctaccac
      301 cattcagaaa cacgtgcggt aatggaaggt ttggaggaag ctatccagac cactaacgat
      361 tgtccctatc gtcgtacgtt tcactcagat caaggttggg cgtatcaaat gaaagcttat
      421 agaaacaaat tgaaggagta caaaatcttt caaagcctgt ctcggaaagg gaactgctta
      481 gataattcac ttatggagaa tttttttggc ttattaaaac aagagatttt tcacgggaaa
      541 gtttataact gtttcgagga attaaaatca gccatcgata gctatatcta ttactacaat
      601 aatgaacgga taaaacagaa attaaactgt caaagtcccg tccaatttcg taaaacaacc
      661 gttacggttg tgtaaaaata tcattttaga gcatgaaaaa aggagtggat ttctccactc
      721 caaaaaagtc taacttttgg gggtcactac atttttgatc ctttttattt gattaattat
      781 atccagctgg ataataattt tgggggcaac atttctatct tactattatc ttcctaaagt
      841 agtagacttt cttattggga aaaattacaa caaaaaggag tggcttagtt gacaactcct
      901 ttttgtttac aaatcaattg gatatctaca aattgtattt tctaacggat tttatagaca
      961 ttaaaaaatt aatttgacgt taaatacttt ctccagaaag tattgagatt ggtaaaatat
     1021 aatccttatt tgtcttttcg cctttaattt ttttcagaag aatatcaaca ataagacttg
     1081 caatttcatc aattggttgt cttattgttg tcaattgtgg gaaaaatttc tcaatgaaag
     1141 aggtaccatc gtatccaata atttttaaat cttctgggat attaagttta agttgatgag
     1201 caattttcat agtgagaatg gctgttaaat catcagaaac aaaaatacca tctggtttgt
     1261 gatttataat agttgacttt atttccattt cacgacggat agtagacaga ttattaggaa
     1321 ttttgaaaat ttttccattt ggattttgaa aagaaaaacc tagtgcacgt aattctgtgg
     1381 gagaatccgt gttatcattt cctgtaatca taatggtatt ttgacaacca tttttttgta
     1441 aagtcttagc tgcaagtttt cccccttcaa agttatctga agaaacaatg gaaacattag
     1501 gagctaaatt tctatcaaaa gcaacaatag gtgctctcac acgctcataa tcagcaattc
     1561 caagattatg gcttgatgag attatgccat caacttggtt ggcttcaagc atttcaatgt
     1621 attctctctc tttagcagga tcattttgac tattgcaaat aatcgtttta tatccatgtt
     1681 taaataactc tatttcgaga tactcaatga gttcagagta aaagatatta ctaatattag
     1741 gaaaaataag accaataagc tgaggtgact ttccttgaag tccacgtgct aaattatttg
     1801 gtttataacc aagagttttc atagcttcat gaactttttg ttttgttttt tctgataaat
     1861 atcccttatt attaatgacg cgtgaaacgg ttgttgggct aactccagct aattcagcga
     1921 catcagttaa ttttgctacc attttaatat tttaattcaa agtattttcc agtaggttcg
     1981 cctgatttga tttgaatacc attttggtga ttttcaggga atacacgact agtaaacact
     2041 ttttctcctt tattaataaa aatctcaatg attgagttat ctacaaaaat gttagcagtt
     2101 gtttctttag tatcaattga gcattcacga atcgtaccaa agtcagtggc atattgaatg
     2161 cctgctttgc tgcgatctaa aataattttt ccttctttgg tatctacaat caagctaagt
     2221 ccatttcctt tactatcaga gaaaagaagt aactccgatt tctgatttgg aggaaaagtt
     2281 agttcaagct cataagtatt atttgtttct gcttttgctg taaattgttc agaactagca
     2341 cgtaatgatg taatagcttc tactggatat tggtaaagtt taccatcttt tattgaaagt
     2401 tcttttacaa gactcattgc tccctgataa tcatacttat cagttggata atcgatatca
     2461 ggtagtccaa tccaactgac aatcagagca cgaccatcag gagtattgaa tccttgagtc
     2521 gcatacgctt caaatccata atcaagattt tgaatttctg aagcgcccac aagttttact
     2581 ttttctatgt caagcgattg acagatctta aaagtattcg gatagatatt cccataattt
     2641 agctcagatt tatccaaccc ttgaggacaa taaatgagaa caggtttttt gtctacaaat
     2701 actagatttg gacactcaat catgtattct gaaccagtgc cgccaaaatc aaggttgcca
     2761 acttcctccc atgtttccac gttattgtca tccgctttgt aaagtttgat aaagcctgat
     2821 ttttctaaat tttgtgctcc aacaatcgca tacaattgtc cttcataatt aaacatttgt
     2881 ggatcacgaa aatgatcagt tacatcagca ggtttatgaa taagaacatt ctcacctttc
     2941 gtaatgttgt agtctttatc catccatgct ccgatttgaa gtgtatcacg ttcccaattt
     3001 tcatttcgaa cgtttcctgt atagagtaag aatagattcc cctctatttc atatgcagaa
     3061 ccggaataag cgccgtggct atctcgtttt gtgtctggaa gaagttctgc tcctgttaca
     3121 tgaaaatgaa ctaaatcatc tgattcattg tgtacccatt ctttcaaccc atgagcagct
     3181 ccaaatggcc aattttgata aaaaagcgta tattttccgt taaaaaaaga aaaaccatta
     3241 ggatcgttta acaatcctgt tttaggttcg atatgatagc tagcacgcca aggtgatcgt
     3301 tttacattat ccttaatttt atccatctca tctttagtcc aatcagaata agcacgatat
     3361 cgtatttctc gaggtaagtt catattttac tccttcaatt tatcttttta caactagtat
     3421 ggtaaacgtt ttccgttgaa aaatcaatca tttcatttaa aaaaataaac tatatgacaa
     3481 acgtttgaca tatttttaag atatgctaaa ataaatttgc atttcagtga accgttttca
     3541 cgtaaaaata aaaaaggagt gattcgaatg aattacagta aagtagcttc cgacgtaata
     3601 caagcggtcg gaaaagataa ccttattgca gctgcacact gcgctacacg tcttcgtctc
     3661 gtactaaaag atgacacgaa agtgaatcaa aaagctttag acgaaaatcc agatgtgaaa
     3721 agcacattta aaattgatgg acaatatcaa gtgattatcg gtgcaggtga tgttaatttc
     3781 gtttatgacg aacttatcaa aaaaactgga ctttcggaaa tttcaacaga tgatttaaaa
     3841 caaattgcta gtaaagataa aaaattcaac cccattatgg cattaattaa attattatca
     3901 gatatttttg ttccaattat acctgccctt gttgcaggtg gtttattaat ggcattacaa
     3961 aactttttaa cagctgctgg actttttgga ccaaaatcaa ttgaagaaat gtatcctgcg
     4021 attgaaggta tttcctcaat gatccaactg atgtccgctg caccattcat gttcttacca
     4081 attttagtag gtatttcagc tgctaaacgt tttggagcaa accaatttct tggtgctgca
     4141 attggtatga tcatgacaac accagatctt ggtggctcaa ctgaatattg gaatattttt
     4201 ggttatcatg tttcacaaac aaactatgct tatcaagtta ttccagtttt agcagctgtt
     4261 tggatattat ctatattaga aaaattcttt cataaaaaat tgccatcatc tattgacttt
     4321 acattcacgc cattattatc agtaatgatt actggatttt tgactttcac agttattggc
     4381 cctgtaatgt tattgttgtc taatggaatt acagacatta ttgtttggct atataacact
     4441 actggattta ttggaatggg tatttttgga ggaacatatt cacttatagt catgactggt
     4501 ttacatcaat catttccagc tattgaaact caattacttt cagcgtggac aaatggtatc
     4561 ggacatggag actttatctt tgtagttgca tctatggcaa acgttgctca aggtgctgca
     4621 acatttgcca tttggttctt aactaaaaat tctaagacaa aaagtcttgc ttcctctgcg
     4681 ggtgtctcag cacttcttgg aattacagag cctgccttgt tcggagttaa cttaaaatac
     4741 cgctttccat tcttttgtgc tttaattggt tcaggaattg ctacagcagt agcaggatta
     4801 cttaaagtag ttgctgtttc acttggttca gcaggtttct tgggatttct ttcaattaat
     4861 gcaacatcta ttccatttta cgtattgtgt gaattgatta gctttgtagt tgcttttgca
     4921 attacttact tctacggtaa aacaaaagct gctggtatct ttaaagcaga agaaattgct
     4981 gaacaaacac cagttaattc ttcaaaagta gcaacaacag atccaatatc tactgatgtt
     5041 gaatcaacac aaacaaaagt ttcatcagaa acaattgtta gtcccatttc tggtaaagtg
     5101 attagtcttt cttcagtaaa tgatccagtc ttttcatcag aagctatggg aaaagggatt
     5161 gccattaaac caaatggaaa cacggtccat tctccagtag atggtactat tcaactcacg
     5221 tttgaaactg gacatgctta tggtattaaa tcaaataatg gtgctgaagt tctaattcat
     5281 attggtattg atactgtatc aatgggagga aaaggattta cacaaaaagt tactactaat
     5341 caaaaagtta gaaaaggcga tattcttgga gcatttgacc gttcaatgat tgagaaagaa
     5401 ggtcttgatg atacaacaat gattattgtg accaatactt cggattattc agaagtaaat
     5461 atagtagctg aaaatacagt cactgagggt actgatttac ttgaaatcaa ataaatatat
     5521 ttccctgagt aaagatggaa ttttctttcc aaaatcaaat aatatagatt aatcaaatat
     5581 ttgagaataa cattttattt aatcttttca tatatcaatt gtatgaaaaa ttattagaat
     5641 tttaaaaaat gataaaaatt caaaaagaaa aa
//
LOCUS       DAYYEF010000101         5557 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000101 DAYYEF010000000
VERSION     DAYYEF010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5557
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.106"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(93..1997)
                     /locus_tag="ACHA1B_002726"
     CDS             complement(93..1997)
                     /locus_tag="ACHA1B_002726"
                     /EC_number="7.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0015662 - P-type ion transporter activity
                     [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0019829 - ATPase-coupled monoatomic cation
                     transmembrane transporter activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HFM8703438.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            complement(2195..2428)
                     /locus_tag="ACHA1B_002727"
     CDS             complement(2195..2428)
                     /locus_tag="ACHA1B_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HFM8703439.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            complement(2575..3429)
                     /gene="lgt"
                     /locus_tag="ACHA1B_002728"
     CDS             complement(2575..3429)
                     /gene="lgt"
                     /locus_tag="ACHA1B_002728"
                     /EC_number="2.5.1.145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA];
                     GO_process: GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HFM8703440.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            complement(3414..3752)
                     /locus_tag="ACHA1B_002729"
     CDS             complement(3414..3752)
                     /locus_tag="ACHA1B_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703441.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            complement(3980..4684)
                     /locus_tag="ACHA1B_002730"
     CDS             complement(3980..4684)
                     /locus_tag="ACHA1B_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_function: GO:0030552 - cAMP binding [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HFM8703442.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            complement(4829..5401)
                     /locus_tag="ACHA1B_002731"
     CDS             complement(4829..5401)
                     /locus_tag="ACHA1B_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HFM8703443.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
BASE COUNT         1562 a         1280 c          944 g         1771 t
ORIGIN      
        1 aaaaaagcgg aaaatcccag atttaaaaat ctgagtttcc gcttttgtca tttcaaggat
       61 ggactattgt ctcagcctct tctaatttat tcttaagata tttttacttt ctctgcaggt
      121 gctgatactt ctttttgttc ttttcgacct ttcaacttat acttcattaa tctcatgcca
      181 ttgaaaatta ccaccaagat actaccttca tgaaccaaca ttccgataga catattcatc
      241 cattcgctga agaagacgct ggtcaacaag accaacacta ctccaattga aatcacgata
      301 ttttgtttca tattatttgc ggtggctttt actaatccta atgcgtgagg caagttgctg
      361 aagttcgagt tcattaaaac gacatcggat gtttcaatcg ctacgtccgt tccgcttccc
      421 attgcgattc caatgtctgc taaagctaag gacggactat cgttaacgcc atctccaaca
      481 aaggctacaa tttgaccacg ttgttgaagt tttccgatat aagccgattt gtcttccggc
      541 aacatgtagc cgtgagcttc ggtcaaacca agttcgccgg cgaccacatc aacggttcct
      601 tggttatctc ctgaaagaac gactagattt ttcacgccca agtcttttaa ttcctgcaaa
      661 ttagctttca cacccggacg gacttgatcg cgaatgccca tcagtacttt taattcaccg
      721 tcgaccgctg tcaaaacgag agagttccct tgttgttcaa accgtttgac atctttttgc
      781 acttttttgc tgagagtgac attttctttt tccatcaagg ccacattccc aacagccact
      841 ctatgtccag ctacacttga aacgattccg ccgcctttca caacttcagt tccttcaaca
      901 ggataaaagt ttgtttctcc aatttgattt aagaccgctt ttgctaatgg atgatctgat
      961 tcccgttcca cactggccag atagccaagc gtttcagcag gatctttttc atacagttca
     1021 gtcgctgcaa cggttgggtt tccgacagtt aaagtacctg tcttatcaaa tacaattgta
     1081 tccacattac tgaagtcttg aatgacttca ctccctttta aaagaacacc gttacgagca
     1141 ccattcccaa taccggcaac gtttgagaca ggcactccga taactaatgc gcctgggcaa
     1201 cctagaacca agatggtgat tgctaactca atattttgac tgaacgccca tacaacaatt
     1261 gccagaacca agacagctgg tgtgtagtat ttagaaaagc gatcaatgaa ccgttccgct
     1321 tcggatttag aatcttgtgc ttcttccacg agttcaataa tttttccaaa tgtggtgtcc
     1381 tcaccaactc ggtcagctct gatttgaatc gttccgtttt ctaaaatggt tcctgcaaaa
     1441 acttctgcat cagctagctt gttgaccgga atagcttcac ctgtaatgct agcttcattg
     1501 atatgccctt cacccgtaag gactatgcca tctactggaa ctttcgcacc cgttttaacg
     1561 agcaagatat ccccttcatc tatatcatcc acttctactt cttcaaattc gccattatcc
     1621 atttgtttca aggcgctttc gggtgccatt tcagtcaatt ctttgatagc agatcgcgtt
     1681 tggttcaatg ttcgttgttc caagtagtgt ccgaataaga ataagaacgt gacaatagcc
     1741 gattcttcat aattttgaat aaaaagcgca ccaatcgctg caatactgac taagacatca
     1801 atactgatga ctttgacttt cattgcttga aacgcttgaa tggcaattgg cgtaatccca
     1861 aagacagagg cgatgatcaa agaccactct gaaagtccta cgttttctaa aacaaagtga
     1921 ctgaagaaac cgagtacgat taacaatcca ctgatgacgg tgataacatt tttcttgctt
     1981 aatatatatt gttgcatgct ttttccctcc aaatttaatt tctcttttat tgataaacac
     2041 agtataagat aattgcctaa gtaattaatt gactgacatc aagtttagaa agttctcttt
     2101 tatcgtttct aagcacctcg aatcggattg caacaaaaaa agcaatcctg gaaaaatagc
     2161 ttttcttcca gaattgccta gttcatttaa tctgttaaac ggccttgact tttgctttaa
     2221 gaaccggata gcctacgttt tcgatagctt tttgaatctc ttcaatcgaa gtgacagctg
     2281 aatcaaaatt ggttttgact ttgctggagt tgaataatac tttaatgctg tctttatcaa
     2341 taccgttaac tgatttcacg gcaccttcaa ttttttgcat acaacttgga caagacaacg
     2401 tttctaattg caatatagct ttttccataa ttcctatctc ctttatgtgt ttttatttta
     2461 tcggcagcag attaatgaac actgcctttt cctctttaca actgtagtat agctcacttt
     2521 tagcaaacga aaattgacgc atatcaagtt ttgcacttct ttttatcttt ttgctcaatt
     2581 caccatctta atagtctttt tctgcccctt attgccatca gaataataag aaattggtgg
     2641 ataatcttgt ctgcgtataa accatactac aatcgcgcca ataaacaggg ccagagacaa
     2701 ggcttgcgaa acgcggatcc actcgccaat ccataaactg tccgttcgca taccttcaat
     2761 gaagaaccga cccactgagt accacaaaac gtaactcaaa gcgacttctc cttgacgcaa
     2821 aagctgtttt cggttccgta tagtgacgat gaggacaaag cccaacaaac tccacaatga
     2881 ctcgtataaa aaagtcggat ggtagtaggt accattcata ttcatttgtt caatgataaa
     2941 ttcaggtaaa taaagatttt ccaagaattg acgagtaacc ggcccaccat gagcttcctg
     3001 attcataaaa ttgccccaac gaccaatgga ctgggctaac aatacattgg gcgctaaaat
     3061 atcaagaacg agtgccaaag aagtaccttt tttctttgca taccaatata gcgtaccccc
     3121 tcctgcaatc aatcccccat aaatcgcaat gccgccattc caaatcgcaa ggatttgtcc
     3181 tggattttgc agataataac caagttcaaa taacacataa taaagccgag cgccgaggag
     3241 tccaatcgga attgcccata aggccatatc gataatggta tcctcttcca gtcctttttt
     3301 ctttgcttcc ttggtgctca actggagagc cgctaatatg cccgctgcaa taatgactcc
     3361 ataccaatga atcacaacag aaccaatctc caccacatgg ggattcaaaa cgcctaatac
     3421 gaatcccatt ctatttgctc catttcttca atttttcgcg tcattctagt catggtgatg
     3481 ctgaacaaga ttccggctaa gctccatgga aaccaaacag tgaatacact tttatctccc
     3541 tggtcactcg cttcgtaata cgccactttt ccgtgtccga ttacgccggc tccttttaca
     3601 acttcctctt ctttttccat agctaaccta tctgcctcaa caacgttaga cgtttttgct
     3661 tcgccgccaa tcgtgttctt ggtgaaaggg acgacaaaga atgcccccgc tgctgacaac
     3721 gtgatggcaa ctatcaccca aaaacaatgc acattcaccc tacttatttt tacgttttgt
     3781 tcgacaaccc tatcttaaag aaaaataaaa caaaaaaact tgagggttat catgtttgtg
     3841 cttttatttt tccaatgaat gaaggtcgtt ctgtcttaaa aaagccaaaa acggacagat
     3901 ggaagcaaaa gcactgagtt ctgtcccgtt gttaatgaag agcgacagaa caccaacgtg
     3961 tagaaaaaag tgtgtccgat tattcgctgt aaagcaataa atcatctaaa tcctgaatct
     4021 tgatcctttt cccagacagc tgttgaatca atccttcgtc ctccaattct ccaaatttgc
     4081 gactgatggt ctcaggtgtc gttcctaaat aggaagcaat gtcctttttt gccatcggca
     4141 gggtgatggt gggagagttg cccatttcag gttccacatt ttctgccaaa aacaaaacta
     4201 aacgggtaat gacactctcc acggctactt gtgtcgtttg acgttctgaa ctttctaacc
     4261 gtttagacat ttccgccaat agttttaaag aaatagctgg gtattgttcc agaaaatctt
     4321 ggacatcttt ttgctgaatc atacagacaa cggtatctcg ggttgcttcg gcatattcct
     4381 cgtgtactgc atccgggttg aacaaggtcc attctccggt gaaatcacca gggttcaaga
     4441 tccgcactag ctgctctttg ccagagtctg ccaatcgata aatacggatt ttcccacgat
     4501 tgataatata taaagtatcc tctttttctt gtgaacgaaa cagaaactct cctttttgat
     4561 actgtttcgt gtgggctttt tcagcaatgt aattcatcgc gctatcctct aagtgattga
     4621 atattggaac caagcggata caggctgcgt ggtcgccaat ttcatgatgg gtatgtttag
     4681 tcaattcatt ctcccccttt atttattttg tttatattcg ctgcttttat tatataagtc
     4741 tcttactaca aaaaaattga tgcacatcaa gaaaatggaa aaaggactgg aaagaattcc
     4801 aatccctaaa tcagcttcta cttttacctt aatcttcatc ctcatcaaga gcgtcatcat
     4861 cttctaatgc ttctttacca atgaacgctt gcagcatcca aatgttcttg tctaagtcat
     4921 ttttaaaagc aatcaatgta tcttctaaag catcgtcacc ctcgtcttga gctaaacgaa
     4981 tcgcgcgaat agttaggtca cgagtgcttc tgaagtcctc gataatattt tcaaccatgt
     5041 cttctgcttt agcgtattta ttaactgcat cttccgaaag catcgaatat ttttcaaatt
     5101 caaccgttgt cgaagcaggt ttatgcccag aagtaattag acgctccgca agtttgtcga
     5161 accatttttc attttcgtta tacaactctt caaatttttc atgcaacgta aagaaattgg
     5221 ctccttttac ataccagtga tattggtgca gtttcacatg taatgtatgc atgttgccta
     5281 aaagatgatc cgcaatggcc gctgcattaa ttttcgtatg atgaacatgt tccttgtgtt
     5341 cttgttcttc ttgcaatctt tcttggggtg ttctttcttg agtagcttta ttttcagtca
     5401 tgatttattc ctcctataat tttggtttgt ttaaaatagc tttctttgat tcctcctttt
     5461 tctttactga atttagtata ggatagattt ccgttaaaaa aattgacgct catcaagaaa
     5521 attatttctt aatagacgcc aggcttctct attaaat
//
LOCUS       DAYYEF010000102         5268 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000102 DAYYEF010000000
VERSION     DAYYEF010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5268
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.107"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(29..1177)
                     /gene="nagA"
                     /locus_tag="ACHA1B_002732"
     CDS             complement(29..1177)
                     /gene="nagA"
                     /locus_tag="ACHA1B_002732"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA];
                     GO_process: GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HFM8703444.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1253..2089)
                     /locus_tag="ACHA1B_002733"
     CDS             complement(1253..2089)
                     /locus_tag="ACHA1B_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703445.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2273..3490)
                     /locus_tag="ACHA1B_002734"
     CDS             complement(2273..3490)
                     /locus_tag="ACHA1B_002734"
                     /EC_number="2.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA];
                     GO_function: GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA];
                     GO_process: GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HFM8703446.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3639..3800)
                     /locus_tag="ACHA1B_002735"
     CDS             complement(3639..3800)
                     /locus_tag="ACHA1B_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703447.1"
                     /translation="MEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGIAMDWAA
                     NLWNDYHDN"
     gene            3873..3956
                     /locus_tag="ACHA1B_002736"
     tRNA            3873..3956
                     /locus_tag="ACHA1B_002736"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3907..3909,aa:Leu,seq:gag)
     gene            complement(4196..5268)
                     /locus_tag="ACHA1B_002737"
                     /pseudo
     CDS             complement(4196..5268)
                     /locus_tag="ACHA1B_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1630 a         1074 c          835 g         1729 t
ORIGIN      
        1 tttagtttta aggttaactt aaattatatt atgcgtggaa acgttccacg ccatctagat
       61 aagttgcttc caatgtcata tcagggttca atacgataaa gtctgcatcg cgtccttgag
      121 cgatttttcc acatgtatca tcgattttac agctgattgc tggaatcaga ctagccatca
      181 tgactgcttg ttctggtgtt gctaatcccc agtctacaac atttttaatt gcttctttca
      241 atttcaatat acttccagct aagttgccag attctagacg tgctgttcct tcttttacta
      301 ctactggaaa ttcgcctaaa ttgtaatttc catcaggcat cccaccggcc atcatacagt
      361 ctgtaattaa tgcgacatga tcatgtcctg ctttttccat taggattccc gcagcatttg
      421 gatgtacatg atggccatca caaatcaatt cagaaaagac atgttctaaa gataataacg
      481 cacccaccat acctggttcg cgatgattca atccacgcat accattgaaa gcatggacaa
      541 atacacttgc gcctgcttca acagcttttt gcgcttcttc tagtgtagca ttactgtgtc
      601 ctagagaaac aactactcct tcttcagtca cttgtttgac aaactcttct acaccttgac
      661 gttccggtgc taaagcaatt tttttgatta aaccacctga agcttcttgc cattcatgga
      721 aagtatccaa atcaggatcc ccgaaataac ttgggttttg tgcccctttg tgttcttctg
      781 tgaagaaagg accttcaaaa tagattcctt tgattttagc tcctggtgct tcctgataca
      841 ttttgccgat tgtctcagct acatctttta aacgttcttt gcttgacgtc aatgttgttg
      901 gtaaaaatga agtcactcca caagataaca gaccttcaga catcactttg atgccttctg
      961 catcattatc cattacatca tgattcatat agccgtgaat atgtgtatct accaaaccag
     1021 gagcaatcca tttgccgctt tggtcaatga tgttgacttc tccctcaggt agttctttgg
     1081 tgtattcacc aaaaagtcca tcggtaattt caagatagcc tgcatgtttg acacctgacg
     1141 ctaaaaagaa tttgtcagca tagataaaag ttctcattct attctctccc tttgtttttc
     1201 tacctctaaa gtactcttat ttagagaaga agtcaagaat ggtctacacc atttacaaat
     1261 tttttgaaat ttgtttcaca gcttgtgcta agccttcata gaatgctgct ctttctggtt
     1321 cttctttacg cttgtatatt aagcttttaa gcacaaataa atcattgagg taatagtagc
     1381 tattcttctc ttgagcccaa tagattcctt gattcacctg ttctaacgct tcgtcgattt
     1441 cattttgatg gaataagaaa tttccataat tataaaaaat ttgcgaaaat tcactttttg
     1501 atcgttcatc agctgattga tgcagcagtt ggatgcttcg actcaaatag tagcgtgctt
     1561 cagccgtttt tcctgccaca ccatatattt ttccgataca actaatcagt tgtatttctg
     1621 tgtcagaaac atggattctt tctttttggc tagagtagct taatgcttct ttcaaataat
     1681 aaagggactg agagatattt tgacgcaacg tgaattcgca aacaccgaga taataataat
     1741 agcgttgaaa gtcagttgct tgatacagat tttcagaaat atcagaagat tttagtactt
     1801 gttctaactt ccgataatca cgtttttgga aacaactatc caacagttca aataatttat
     1861 cgtttgtccg agtagttttt cgagagagat tcatcacatg atcaatcgtt acccctagcc
     1921 gttgacaaat ctgcatcatc accaatacat tcggcagttc ctcattattt tcgatccgac
     1981 ttaatacact ttgtgaacaa atatcatgcg aaagcatttt ttgcgtcatt ttttgttctt
     2041 ttcgaatctc tttaatgatc gttccaaagg actcgattaa cgtttccata agtatcctcc
     2101 ccaaaatatg cgtattcgca ttctattcgt attttacttt aggaagtcgc aaacttcaag
     2161 aaaagacttg caactaaata atatacttta gttatttaag aaaactccac tagaaagaga
     2221 gcctcagtgt gtttgtctgt ggccctccta ctgaaaaatt tggtttttaa aatcattttt
     2281 ggcgataggt tgctaggaat tctctcattt tcttagctgt ttgtttcaaa tcatccattt
     2341 taggaagata aacgattcga aaatgatctg gctggttcca attaaatcca ccaccatgta
     2401 caagtagaat atgatgttca tgtaaaaagt ccaaaacgaa tttttcatca tccaaaatat
     2461 tgaatcgctt tgtatcaatt tttgggaata tataaaaagc agcttttggt tttacggctg
     2521 aaagaccagg aatatcattg attgcattat agatatattc tctttgttca tagatccttc
     2581 cgcctggcag gagcagctca tcgacacttt gataaccgcc tagcgcggtt tggataattt
     2641 gctgagacaa tacattggaa cacaaacgca tggaggacaa catattcagc ccttctatat
     2701 agcctttgac gtgtgactta tctccactta ggaccatcca gcctactcga aatcctgcta
     2761 cacgatgaga tttggataga ccgttcagcg taacaacgaa caaatcaggc gctaatgtag
     2821 caatcggaat atgttctaga ccatccatca ctaagcgatc atagatttcg tcggaataaa
     2881 taatcaggtt attttgtcga gctacttcaa cgatttcttc taataattct tttggataaa
     2941 gtgccccagt aggattatta ggattaatga taacaatagc ttttgtccga ctcgttattt
     3001 ttgatttgat atcatcaata tcaggatacc attctgcctc ttcatcgcaa atataatgaa
     3061 caggtgtgcc tccagctaat gcaatagaag ccgtccacaa cggatagtcc ggcattggaa
     3121 ccagtacttc atctccattg tccagcaacc cctgcataca catcgtgatc aattcgctca
     3181 ctccgttgcc ggtgtagata tcattgatcg tcacattcgg aaaatgtttc agttggcaat
     3241 attgctcaat tgcttttcta gcagaaaaga tccccttgga atctgagtag ccttctgagt
     3301 cacgggcatt catgatcaaa tcacgaatga cttcgtttgg tgcttcaaat ccaaaaggtg
     3361 cgggatttcc cgtgttcaat tttaaaatac taatgccctc ttcttgcatc cgctccgctt
     3421 cttctagaac gggaccgcga acatcgtaac tgacaccttc taatttgttg gatttttcaa
     3481 attctctcat cacttagcca atccctcatt tcaaaaagtt agaactttcc aaattttttg
     3541 ttatttacta tttcaatatc atactccatc ctagaaaatt ttgccactta tttaggaaaa
     3601 acgtaagtat taaaaaaaca caaacaagcg ttgagaactt aattgtcatg atagtcattc
     3661 catagattcg ctgcccaatc cattgcaatt ccacaaatga ttcctagcat aaaaccaagc
     3721 aaaaaacgtc cgaatgcaag tccaatcaat acacctaaga tcattcccag tcctgaaaat
     3781 tctccgtcat atttctccat cttaataagt cctcccattt ttgagcttga caactatgta
     3841 aaacctcgct atcattagtg tgttattatt acgcagatgt gttggaattg gcagacaagc
     3901 atgattgagg gtcatgtgag cgttagctcg tgtgggttcg agtcccatca tctgcactac
     3961 aactcgtgaa gttaattttg cttcacgagt ttttttgttt gaacgtttct ttatgccatt
     4021 atatacatat cactgtatcc tttacaaaaa gaacgtacaa tcatgtaaac agcctgaggt
     4081 gagtatatga aggtcggaaa caagctactc gtagaaactt gcaagtgtta aaacaattaa
     4141 tcgaaaaacg agtaaaatcc ctcacctaat actaaagcga gggatttttt gtatattatc
     4201 tgtttatcac cgttattata aaggtacaaa taccaagcac ggttaatcca aattgcataa
     4261 attcattttt ttgtacactc atgcttttca ttagctcttt aactgccatt agtactaaga
     4321 tggcgataac aacataaagt atatagtacg tccgcattcc ggaagcccat actgtgggag
     4381 aaaatcccat aattaacctt gaacaaaatc ccattatcat caaaataact aaaaaaatag
     4441 aagttttctt attgtcaaaa cttaaataaa ttccaacaat taaacatagt aataatgcca
     4501 agactactaa agtagctatc caagtacctg gataaaaaag tgacagtttc gttcctaact
     4561 ctgtaaagag attattcagg ttactactac tccaaatcat tgccctttta tttccattga
     4621 cgtaagtaaa gctttgaccc attgtattac caaaataaat aatcaggttt aagaaaaacg
     4681 gtaatgcagt caatatacgc acataatagt tttgacattt cctatatgtt agaaggaaaa
     4741 ttaagaaaaa tagcaataaa aataagatat tcatgtctaa aaaaacggct ttccaaatga
     4801 tgaaatacct aaatctaact tattaagaaa gttgaaattt ttatattcag gaaaccattt
     4861 attaatttca tgtgcagcac gtaatgcatt ccctggagtt gtcaaagaga aaattaattc
     4921 tgctaagctt attattgaaa atactgataa cttataatta tatcgtccat tgacaatcaa
     4981 atataaacta actatacttg ttagaacaaa aaaacaggcg ttgacttgtt cttgattagt
     5041 taaaaatatc aataaaggaa tacttaccca atatattttt ctatttattt cttctcctct
     5101 taagagttga aaaaacggat aaaaagttag taaactaaat gctactggcc actgatagtt
     5161 caaggtggtt gctctccaac cggtttcccc cattactgtc aatggtatta aacagtatat
     5221 agagcaaacc aataataaat ttttaacatt tattttctca aaaacata
//
LOCUS       DAYYEF010000103         5207 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000103 DAYYEF010000000
VERSION     DAYYEF010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5207
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.108"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1368
                     /locus_tag="ACHA1B_002738"
     CDS             <1..1368
                     /locus_tag="ACHA1B_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703448.1"
                     /translation="SFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIAL
                     TIIPAVLYYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSK
                     QIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDS
                     IIQALNNDITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFL
                     FQKTPISLLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIA
                     AKENYAKVIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGE
                     SWEKGKYKAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVD
                     VNAGENKIEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINK
                     KNENK"
     gene            1355..2989
                     /locus_tag="ACHA1B_002739"
     CDS             1355..2989
                     /locus_tag="ACHA1B_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-pyruvoyl-tetrahydropterin synthase-related
                     protein"
                     /protein_id="HFM8703449.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3164..3997
                     /gene="msrA"
                     /locus_tag="ACHA1B_002740"
     CDS             3164..3997
                     /gene="msrA"
                     /locus_tag="ACHA1B_002740"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA];
                     GO_function: GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA];
                     GO_process: GO:0006979 - response to oxidative stress
                     [Evidence IEA];
                     GO_process: GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HFM8703450.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4077..5066
                     /locus_tag="ACHA1B_002741"
     CDS             4077..5066
                     /locus_tag="ACHA1B_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HFM8703451.1"
                     /translation="MYIADSARYEKMEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQ
                     REILRGAFDMGITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMW
                     EGPYGEWGSRKSIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGK
                     ALYIGISNYNGEDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGA
                     ITFSPLAQGLLTNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQS
                     LAQMALAWNLRQKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1825 a          806 c          951 g         1625 t
ORIGIN      
        1 agtttttatt atggagaaaa gttttttaaa aagatagatg ctgctttttt atttagttgt
       61 ttatatactt ttgcaactta tcgaacagtt gatatctatt atcgatccgc aattgcagaa
      121 gcaatcgctc ttacgattat cccagctgtt ttatattatg cttatggatt gatattcaat
      181 agagaaaaaa aagtcatcgc tttatctgtc agtataagtc tacttgtgta tactcatgtc
      241 ttaactacac tattgtgtag tgcattgatt gcttgtatga ttatagttcg tttgttttta
      301 agcaagcaaa taaaaaacga tataaaattt gtggtcgtga atttagtaaa ggctgttttt
      361 ttgacttgtg cattaactag ctatttttgg tatcctatgt tgcagcagat gaattatcaa
      421 gaaatacaca gtcccttcaa aacagatttg cagctagaag cactttctat ttcagatagt
      481 atcattcaag cgttaaataa cgatattaca acatacacta tggggttatt aggattggtt
      541 gcgttgattt ttcctttatt catactgaaa gaaatggaga aaaaagaaaa aatcatctat
      601 gttggcgtag tttctacatg ggtatgcgta actaatttat ttccatggtt tttgtttcaa
      661 aaaacaccga taagcttgct ccagtttcct tggcgtatct taggtatcca aatctttttt
      721 tcttcaatga tcataacgct tgtttttatg aaaaagacta tgaataaaaa atattcatgg
      781 ttaatcattg gcgctactgt ggtgtttcta ctcgtcacgt ctatagcagc aaaagaaaat
      841 tacgcaaaag ttatccaatc aaaacacggt catattgtta tcaatgaaga aacactccca
      901 cgttatacaa catcagatat gggaggatta tacgattacg ccccaacaga agcgataaaa
      961 gaaaggcctc acttagaaaa acatgaagta aaagtaggag aatcgtggga aaaagggaag
     1021 tataaagctg cagataataa cattacttac acagtggcaa gcaacaaaaa gcaaaaagtg
     1081 acagtaccag tatatgctta tttaggtaca caggtaaaag taaacggtaa agtcgtaaat
     1141 gactcttata aaaaacatgg cttagtgaat gtggatgtaa atgctggaga aaataagata
     1201 gaaattacaa caaaatatac tccaactgct ctcatggctt tatggatcag tattctgact
     1261 tattgtttag tggtgtattc aagttttaaa cgatttgcac ctaataagtt gaaagattct
     1321 cgatatgtga ctaaaaagga gataaacaag aagaatgaaa ataaataaaa aagtagtaat
     1381 attgagtgga ttaattatag ttagtagtat atattctttc atctttttca aaaatacaca
     1441 gagtatttat accactggag atctttcttt tcacttatct cgaatcaagg ggttatcgac
     1501 tatttttacc agtccgatta attatgagac attcaattat actggatatg gtgtaaatta
     1561 tttttatccc tttctgactt tttttccagc tgtaatgtta tattggatga caaaaaattt
     1621 gattgtaagc tatattattt acgtttggtt attgaacttg tgtacaacac tcgtagctta
     1681 tcattatggc gagcggtttt taaaacaaaa aaaagcggca tttttattta gttgtctcta
     1741 tattttctct gcttatcgga cagtagacat ctactatcgt tccgcaattg ccgaagctat
     1801 cgcaataaca cttgttatcc ctgtattatt ttatgcttat caaatcatct ctggaaaaga
     1861 agaaaagtat ccgtctgtaa agctagcatt gagtatgagt ttgctagtgt acagccatgt
     1921 actatcaaca ttaatgagta cagcattaat tatcattttt atttttattc gtttggtttc
     1981 taaaggtttc aagaatgcag attttattgc tatatttaaa aaattattta gtgcggcagg
     2041 aatgacattg gttctgacga gtgctttttg gtatccgatg tttgaacaaa tgctctacca
     2101 aaaaatcaac aaacctagcg tgacaaattt atatgctcat gcatctaatg tgttcgatag
     2161 tctgactgaa gctatgaaca acgacttaac tacttactca atgggactag ttggtctgtt
     2221 atctttatgt attcccctga ttttatttaa aaaattaaca aacatagaaa aaaagattta
     2281 ttatggtacg tgtttgactt ggctagctac aactagtttg gtgccatggt atcttctgca
     2341 aaatacgcca gccaaattgt tacaatttcc ttggcggatc ttaagcttgc aaataatatt
     2401 ctcttctctg atattaacga tgatattttt caaaaataga agatacaata agacaagaga
     2461 actattttat ttatttatga ctgttttgtt attaatcact ttaactgttt ctagtaaaaa
     2521 aaatttcaat caaaaaataa tttctcagcc gggacatatt gttgtaaaca aagaaacagt
     2581 agaggcgtat accactaaag gaatggatta ttttttatat gattattctc ctatcgcttc
     2641 attggagaat aaggagcata taataaaaca cgaagcaaag attggcagtc aatgggtaaa
     2701 ccttccttat aaaacaactg gtagttctat catatataga gtaactaatg agaagagcca
     2761 agtaatcaca cttcctgtat atgcttattt aggaacgaat gtagaaataa atcatcaacc
     2821 tgtaaaggag caggtgaatg ctaatggatt ggtacaaata agcggagtca aaggagttgc
     2881 tgatattaaa gtaagcacaa gttatacagt aacgactatt atttcttatc ttgttacatt
     2941 aactgcatat ttatgtttat tttttaaaat agttttccat aaaaggtaaa ttaacttttc
     3001 atttataaaa taaattgatt aaaaaggaga atctgtcgat aaggattctc tcttttttat
     3061 acgaaaaatc tgtaggggga tgaagtaatc gcttatttcc tcactttatg ataaattaca
     3121 gctaaagtca ctagcttgtc ttcttcggaa aggaggagaa tctatggatg aggaacaaat
     3181 attcattcaa acactttata atctgatttt gaatccgaat acacgagatt gggaacgaaa
     3241 agtattgatt cagacaaaga atgacataag agaaaatata tccgttaaag aacagttatc
     3301 aaaactagaa gcaacactac gtccattagc tatccgaatg aatctgacgc ctgatgtaat
     3361 ggacttttat ttattgatta cggaaggatt tgataaggag caaaaatatg acttttccaa
     3421 gcatgccatg caagatgctg actatcaaga acgtgcagta tttgcagggg gatgtttctg
     3481 gtgtatggtc gagccgtttg aatcgaaaaa agggatccta tctgttttgt caggatacac
     3541 gggcggacat gttgaaaaac caaattatga tcaagtaagt ggtggttaca caggtcatgt
     3601 ggaagctgtg gagatcattt atgacacaag agaaataagt tatagcgagt tgctgacaat
     3661 ctattggcaa attactgatc ccacagatac atttggacaa tttcaagata gagggaagca
     3721 atatcgtcca gtgatttttt atcaaggcga acgacaaaaa gaattagcgg aacaatcaaa
     3781 acagaaacta gacagttcag gaactttcca ccaaccaatc gtcacaaaaa tcgaaccagc
     3841 cggtacgttt tggccagcag aaaactatca tcagcaattt tacaaaaaac aaccgaaacg
     3901 ttataaaaaa atccagcaag cacgtaatca atttctgatc tatcaacgag taaaaaacaa
     3961 atggcaaaaa aatatacgaa aaaatcattt tgattaactc cttttcttta aaatgtagta
     4021 aactaaaaat agaaaaaaga aagcgtttta aaaagatttg atgaggagga gaaaaattgt
     4081 atattgcaga tagtgcacgt tatgaaaaaa tggaatatcg taaatccggt cattcaggtt
     4141 tgaaattacc gattttatct ctcggattat ggcaaaattt tggtgattat gatcctatcc
     4201 ataatcaaag agagatttta agaggcgcat tcgacatggg aattacccat ttcgaccttg
     4261 cgaataatta tggaggccct gctggagctg cagagaaaaa ctttgggcgt atttttagag
     4321 aagattttca agcctaccgt gatgaactga ttatttctag caaagcaggt tatcatatgt
     4381 gggaagggcc atatggggaa tggggctctc gtaaatccat catttcaagt tgtgaccaaa
     4441 gtctccaaag aatggggcta gattatgttg acatcttcta tcatcatcgc ccagaccctg
     4501 atacaccttt ggaagaaaca gcagaagctt tgatgcaact tgtaagacaa ggaaaagcat
     4561 tatatattgg tatatccaac tataatggag aagatacaaa aaaaatgact gaaattttaa
     4621 aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt tctcgtgcac
     4681 tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca atcacgttca
     4741 gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct gaagattcta
     4801 gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca actctggaaa
     4861 aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg caaatggccc
     4921 ttgcatggaa tttgcgacaa aaatctgtta caagtgtact ggtcggagca agtcggttaa
     4981 gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca gaagaagaat
     5041 tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat ccatatatta
     5101 aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg aacatcatat
     5161 tttttgtcgt tcaaaataaa aatgatcgaa ggctaggagt gaatttt
//
LOCUS       DAYYEF010000104         5087 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000104 DAYYEF010000000
VERSION     DAYYEF010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.110"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="ACHA1B_002742"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="ACHA1B_002742"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016861 - intramolecular oxidoreductase
                     activity, interconverting aldoses and ketoses [Evidence
                     IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HFM8703452.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="ACHA1B_002743"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="ACHA1B_002743"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016823 - hydrolase activity, acting on
                     acid carbon-carbon bonds, in ketonic substances [Evidence
                     IEA];
                     GO_function: GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HFM8703453.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="ACHA1B_002744"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="ACHA1B_002744"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0047590 - 5-dehydro-2-deoxygluconokinase
                     activity [Evidence IEA];
                     GO_process: GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HFM8703454.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="ACHA1B_002745"
     CDS             complement(4028..5044)
                     /locus_tag="ACHA1B_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HFM8703455.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
BASE COUNT         1337 a         1270 c          909 g         1571 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaa
//
LOCUS       DAYYEF010000105         4937 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000105 DAYYEF010000000
VERSION     DAYYEF010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4937
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.111"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            88..327
                     /locus_tag="ACHA1B_002746"
     CDS             88..327
                     /locus_tag="ACHA1B_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703456.1"
                     /translation="MIDISLPEDLKPDPATIGNSGMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVANKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(551..1759)
                     /locus_tag="ACHA1B_002747"
     CDS             complement(551..1759)
                     /locus_tag="ACHA1B_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006701963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFM8703457.1"
                     /translation="MFFLGIDIGKQHHEVGVIDQHGKSIGKTIRISNTKFGSEQLLAF
                     FNKHALLPENTMVGMEATGHYWLSIYTFVHKLGFHTTVFNPIQSDVLRDFYIRKTKTD
                     TIDALLIAQVIRLDLPDKTELPAEDIFRLKQLERFRYGLVDRCSDLKRKILACLDQVF
                     PEYDQIFSDVFGCSSTQVLLNSPIPEDLLEIDAERLIETINTASEKRLGIARSEEKVM
                     KLKEAAAHSFGISIASDVFKLEIQIMLEQIQLLDSQIKIIEAEIQEIVSKQENYLTTI
                     TGIGDITAAVLMAEVGDIKRFERPNQLLAFAGLDASVHQSGDFTGTKNRLSKRGSPYL
                     RRAIWQAAFVAAFKDPALSLYYQKLRKRGKSHGTAIGAVARKLVNIIFAVWTQNKPYE
                     VHFPEDISEK"
     gene            2035..>4937
                     /locus_tag="ACHA1B_002748"
     CDS             2035..>4937
                     /locus_tag="ACHA1B_002748"
                     /inference="COORDINATES: protein motif:HMM:NF033903.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFM8703458.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTATQPTVEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPVT
                     SQPVEETASITIPASETSTPEGEKAAEATPSVKPESSEKQAEEKQRIEETVEQAAATA
                     DKEGKNEENVEKTISSTAASQNQPTKSNKESTASIEDQKKKEQDIPKTGTPTLLVTVP
                     INRSVRVRRTTNTAVLGGRKINWGENIGVTSSPNNPNFTLNYMVRFEINGQVAFCIEP
                     GVAAAEGQVYTATALENYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEVL
                     GTKIPIKNIRIEYDRRKAEIQRLLNNFDVRATFHNQTHTVKSGETLKVKSGNDFLQRV
                     KDIKKPKGVNVSIHGNEAWITVTKEAPEKAKIHFNQIEALGAPLAYRRPGAQTIGVLN
                     PFEPGDSVVNLTILKQGNIRVFKEDVETDVKAQGAASLENAVYGLYQVDGKKIKEITL
                     KNINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDETIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEISLTSKTTGQVVKTVVTDKDGYASFGKNTV
                     VFDTYILSETKGKEGYKLFEPFEVTISEQGQTFHYILEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKNVKLFKYEEWNKKKTPLAGVT
                     FTLYNQAGKALGEYITDQNGEILVKGLVANNYYFIENTPLESFQPNTDKQAFTITFKQ
                     NAPDDGETLLVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNVPILQDGKEITSTLAFIADKANGTKDLEFVVNASVLKGQT"
BASE COUNT         1701 a          896 c         1015 g         1325 t
ORIGIN      
        1 gtacttgttg tatcaaaata agccagtaga acaaccaaac cagtagctag taatgacaat
       61 aatactgggg aatcggatca ttatggtgtg attgatattt ctcttccaga agatcttaag
      121 ccagatcctg caacaattgg caacagtggc atgatttttg attcgttaga tgaagctatg
      181 tcatatggtt ggaaagaaat taaggatgaa ggtagtaatt ggtatggcat gagatttggt
      241 gatggtgaag ttgccaataa agctggtatt ccaattggga aatggacagt tgatttccac
      301 gaagcaggtt ctttttttgt tctgtaatta tagtgggagg gtaaaatcat tgatgaaata
      361 tgttcagata agagcgccag ataaaaatag aagagacagt tcacgtcgtt atcacttttg
      421 gtaacggcgt tttgttttat tatataaaat tctcaggaaa agctagctat gaattagtca
      481 agtgaaaaag gaatttcttt tatctttaag aaaacacacc aaatagacct ccaaaaatcg
      541 aatgaaaaat ttatttttcg gagatatctt cgggaaaatg aacttcgtaa ggtttgtttt
      601 gtgtccaaac ggcaaaaatg atattcacga gttttctggc aactgcacca atggcggttc
      661 catgtgactt tcctcgtttt ctcaattttt gataatacaa ggaaagggca ggatctttaa
      721 atgcggcgac aaaagcagct tgccaaatgg ctcttctaag ataaggagaa ccacgcttag
      781 aaagtctgtt tttggttcct gtaaaatctc cagactgatg aacagaggca tccagtccag
      841 caaaagcaag gagctgattg gggcgttcaa aacgtttgat atccccgact tctgccatga
      901 ggacagcggc agtaatgtca ccaatccctg taatggtcgt caaatagttt tcttgttttg
      961 aaacgatttc ttgaatttct gcttcaatga tcttgatttg agaatcaagc aactgaatct
     1021 gttccaacat gatttgaatc tctaacttga agacatcaga agcaattgaa atgccaaaag
     1081 aatgtgccgc agcttctttc aatttcatca ctttttcttc tgagcgagcg attcctaacc
     1141 gtttctcact tgcggtattg atggtttcaa tgagacgttc ggcatcaatc tcaagaagat
     1201 cttctggaat aggagaattt agtaagactt gcgtggaaga acaaccaaac acatccgaaa
     1261 aaatctgatc gtattcagga aagacctgat ctaaacaagc aagaattttt ctttttaagt
     1321 cagaacaccg atccactaaa ccatagcgga atcgttccag ctgtttcaat cggaaaatat
     1381 cttctgcggg aagttcggtt ttatcgggca agtccaatcg aatgacttgg gcgatcaata
     1441 aagcatcaat cgtatcagtt tttgttttcc gaatgtaaaa atcgcgtaat acatcggact
     1501 gtattggatt gaaaacagtg gtatgaaagc ctagcttatg cacgaaagtg tagatggaca
     1561 gccagtaatg accagtggct tccattccga ccatggtgtt ttctggaagt aacgcgtgtt
     1621 tattgaagaa agcaagcagt tgttcactgc caaatttggt attggagata cggatggttt
     1681 ttccgatcga ttttccgtgt tgatcaatca ctccaacttc atggtgttgc ttaccaatat
     1741 caataccgag aaaaaacatt caatcagatc ctttcaagga tttgtcagat agcggttatc
     1801 ctctctgctc ttggacgata tagcctcgtt agatattcag aaaccaggtt ctatctagct
     1861 cattcatata ctgtcgcaag agaagaggcg tcagtctttt tgaggaagac aaggcttcaa
     1921 ggaggaaaac tacgacctct atctgcttac tacaagttta aaccaaaaag aaggtttaaa
     1981 ggaataacca gtcagaatgt atctgacaat attaatatac gaggaggaat tcttgtgtat
     2041 gcaaaaacga aaatgaattg gttgaaagca ctcgcattgg tggccttttc tcaattctgt
     2101 ttcttggtgg gaactgctca agcacatgca gaagaaacga cggctacaca acctacggtg
     2161 gaagccattg cccaagtcgc ttctgaagtg acagaagtcc aaccagcaga agccggggtc
     2221 ccagctggtg aagccactgt tgaacaggcc cctgtgacag aagcgccaac ggtcaattcc
     2281 aaaacgactc tcgatcagac gattggggaa acacaacacc cagggaatag tcctgttact
     2341 tcacaaccag ttgaagaaac tgcctcaatt acaatccctg cttcagaaac gtccactcca
     2401 gaaggagaaa aagctgccga agcaacgcct tctgtgaagc cagagtcttc tgagaaacaa
     2461 gcggaagaaa agcaacgaat agaagaaaca gtggaacaag cagcggctac tgctgacaaa
     2521 gaaggaaaaa atgaggaaaa cgttgaaaaa acaatctctt caaccgcagc tagtcaaaat
     2581 caaccaacga aatcaaacaa agaatctacg gctagtattg aagatcaaaa gaaaaaagag
     2641 caggacattc caaaaacagg tacacctaca ctgttagtaa cagtaccaat caatcgttcg
     2701 gttcgtgttc gccgtacaac caatacagct gttttaggtg gtcgaaaaat taattggggc
     2761 gaaaatattg gtgttacttc tagtccgaat aatccaaact tcactttaaa ttacatggtt
     2821 cgttttgaga ttaatggaca agtggcgttt tgtattgagc ctggtgtcgc agccgcagaa
     2881 ggacaagttt atacagctac tgctttggaa aactatttga aaaattcaaa tgtacggaaa
     2941 aaaacaagct tgatctctta tttaggatat gtcacaaaca aagacaaatc cgatgaacaa
     3001 tacattgcgg cacaatttat gatttgggaa gttttgggca caaaaatccc aattaaaaat
     3061 atccgtattg aatatgatcg tagaaaagca gaaattcaac gtttgcttaa taattttgat
     3121 gtaagagcta cctttcataa tcaaacacat acggtaaaaa gtggcgaaac gttaaaagta
     3181 aaaagtggca atgacttttt acaacgtgta aaagacatta aaaagccaaa aggtgtcaat
     3241 gtatctattc atgggaatga agcatggatc acagtcacaa aagaagcacc agaaaaggca
     3301 aaaattcact tcaatcagat tgaagcatta ggtgcgccat tagcgtatcg tcgtccaggt
     3361 gcccaaacaa ttggtgtatt gaatcctttt gaacctggtg actctgttgt caatttgacc
     3421 attttgaaac aaggaaacat tcgtgttttt aaagaagatg tggaaaccga tgtgaaagca
     3481 caaggggcag cttctttaga aaatgcggtg tatggcttgt atcaagtaga tgggaaaaag
     3541 atcaaagaaa tcacgttgaa aaatattaac ggtaaagtac aggcagaaat taaagatctt
     3601 gatcctggca aatatgtttt aaaagaaatt aaagcgccga aaggctatgt actttctgat
     3661 gaaacaattg aaattgtcgt tgaacctgga aaaactgtca atgcaaccgc aaaagatcaa
     3721 gtgatcaaag gaaccattga tttagtgaaa gttgctaata aagacttagt cgattcaacc
     3781 aatccagata ataaaccaaa attagctggt attgaaatct ctttgacgtc aaaaacaact
     3841 ggtcaagtgg tgaaaacagt tgtcacagac aaagatggtt acgctagctt tggtaaaaat
     3901 actgttgtct ttgatacgta cattctttct gaaaccaaag gaaaagaagg gtataaacta
     3961 tttgaaccat tcgaagtgac aatttctgaa caagggcaaa ccttccatta tattttagaa
     4021 gacaaagtaa tcgaacaacg tcttaaagtg gtgaaagtgg atcaagaaac aggaaaagtg
     4081 attccacttg ctaatacaga attcaagatt tttgatacct tagccaatcg ttatgtcaca
     4141 atggagattc caaatgatac agaaacgacg gatatcttta aaaccaatga aaaaggcttt
     4201 ttcttaacta acggtacact tacttatgga aaagatcgtt atcgtttgga agaaatcaaa
     4261 gcgcccgtaa attacgtttt gaatcaaaac ccattggtgt tctcgattac caatgataca
     4321 gaaccaatca aagtgatcca ttttgcgaac cgtcaagcac ggaaaaacgt gaaattgttc
     4381 aagtatgaag aatggaacaa gaagaaaaca ccgcttgctg gtgtcacctt tactctgtat
     4441 aaccaagcag ggaaagctct tggtgaatat atcaccgatc aaaatggtga gattttagtg
     4501 aaaggtctag ttgccaataa ctattacttt atcgaaaata caccattaga aagtttccaa
     4561 ccaaatacag acaaacaagc attcactatt acattcaaac aaaatgcgcc agatgatggc
     4621 gaaacgttat tggtttctgt acgtaactac ttgattccgc caaaactaga aacacaagcg
     4681 tcaaataaag ccgatggtga aaaagtggtt gatccattag aaacgatcgt cattaaagac
     4741 agtgtttctt ataccaacct gtttgtcggc aaagaataca ccatttcagg agtattgatg
     4801 aacaaggcaa cgaatgtgcc aattttacaa gatggcaaag aaatcacaag taccttggct
     4861 tttattgcag acaaagccaa tggcacaaaa gaccttgaat ttgtggttaa tgctagtgtt
     4921 ctgaaaggtc aaacgat
//
LOCUS       DAYYEF010000106         4742 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000106 DAYYEF010000000
VERSION     DAYYEF010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.112"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(26..1024)
                     /locus_tag="ACHA1B_002749"
     CDS             complement(26..1024)
                     /locus_tag="ACHA1B_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFM8703459.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1099..1395)
                     /locus_tag="ACHA1B_002750"
     CDS             complement(1099..1395)
                     /locus_tag="ACHA1B_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703460.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1388..1681)
                     /locus_tag="ACHA1B_002751"
     CDS             complement(1388..1681)
                     /locus_tag="ACHA1B_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mor transcription activator family protein"
                     /protein_id="HFM8703461.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1827..2378)
                     /locus_tag="ACHA1B_002752"
     CDS             complement(1827..2378)
                     /locus_tag="ACHA1B_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HFM8703462.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2552..2851)
                     /locus_tag="ACHA1B_002753"
     CDS             complement(2552..2851)
                     /locus_tag="ACHA1B_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HFM8703463.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2878..3153)
                     /locus_tag="ACHA1B_002754"
                     /pseudo
     CDS             complement(2878..3153)
                     /locus_tag="ACHA1B_002754"
                     /inference="COORDINATES: protein motif:HMM:NF017894.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
     gene            3491..4174
                     /locus_tag="ACHA1B_002755"
     CDS             3491..4174
                     /locus_tag="ACHA1B_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HFM8703464.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(4211..4708)
                     /locus_tag="ACHA1B_002756"
     CDS             complement(4211..4708)
                     /locus_tag="ACHA1B_002756"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8703465.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1404 a          907 c          694 g         1737 t
ORIGIN      
        1 tttctttgat aaataatatt ttcaattatt taatcatttg aaaattgtta gtcattccaa
       61 tacgttgaga aattcttcca tctgtataaa cacgaaattg ttttccacca gccatggtcg
      121 tgtttccatc atcatccgtt acaatattaa ttgaatagta gcttccattt tcatcttgca
      181 ttagatcttt catatattca tttgtgctaa ttaaattagt atttgataca tttttatcag
      241 gagaatcata caaccataaa gctttattat ttagcacaga ttctttagca gcttcccaac
      301 ttgaaattcc tgaactactt gtagattgtg tcgttgtagt tgttgcttgt tgagtagatt
      361 cttctactac tggtgtttga ggagtttgtc cattcacaat atcactgaaa ccttgtttta
      421 actgttgatt ttgagtttcg ttaaagtaca gataattatt ttcattacct tgattttgtt
      481 gcgttaaata aactttaggt tgtccatttt gaaaaccgaa aaagtaaaca tgctgcccta
      541 aatattctcc agtttctaca tcagaataaa ctgctactaa attgaaatct gcatgaccag
      601 ttccatcttc tgaccattgt acggtaactg gtgcttcatt gattgccatt ttccaatcgc
      661 cattaatcac ggcttgtggt aaaggagtgc catacagact tacattattc tgaagattgt
      721 agcttttata ttcttgacct aatgtctttc cccattgtgt gacaaaagtt tctaatttgg
      781 aagctttatt cgtatcccac aaagtattct taacctcttc agaagaagat tcagtgattg
      841 aacttgcact tgtttccaca gattgcttca tttctgttgt agtttgttca gttgattgcg
      901 ttttactttt tttagtctca attgttgtat cagtttctat agtcgcttta gtcctcgtat
      961 tctcagatgt acaaccagtg aataaaattc ccattcctat tagtaataac agccattttt
     1021 tcattatatt tccccctttc aatttctccc tcacgtactt attctatcag acaattaatt
     1081 gatctaaatg gtaatctttt aatcgattct ttcccaataa tgtcgatagc ccgtatggca
     1141 gcggtctctt ccttgaggac tctcagatgg attaaaacta gtagaaattt cccttccaca
     1201 tcctctacag cgataagttc tcattatttt tgggctatta gtattatttt tcttagttag
     1261 agctatgagt ccaactatga ttaccccaac tgtcttaatt acttttcctt tatctatatt
     1321 cggatgcgca agcatatatt gatataacca atatccaccg taaattaaac cacctaatac
     1381 aatcagctta gccatgtact cgtctccttt ctttttgttt aattactttt tgaatccatc
     1441 ttgcagagaa accataaact tctgtcaatt gacggatatc tacagttttt tcctgttcta
     1501 tcatgttttc gattcttttt ctaactaact cacgatcgta cattttcatt ggaaaagaaa
     1561 tctgttgccc tcgaaaagca agataaaatt gatagagcaa ttctgaatcc agttccattt
     1621 cctcaaaaaa gtcattcata cttttataag agttactcaa acaagtttca tcaatctcca
     1681 tctacacacc ccctgttatt ttttacataa tgaaaatagc atattactgg gtacattgat
     1741 aattcatata acatgtatca tcacatgtat ttttaaagtc aaaaagcatg taaaactact
     1801 tataagtaac atgagaaaat aaaatgttat ttttcttgaa ataataattg actatctgcc
     1861 aattgccatt cattacgaac atgaatactt agtgggtggg ataacttacc ttctgcattt
     1921 atcaatactt tggtcatctt cttttgtttc gcactcaatt gatcgtaaat agtctttgct
     1981 tgttcataag ccacttgact cgtcgctgta atcgaaccac aagcaaaaat aatggtattg
     2041 attttctttt ctgtaaaaac agtcgttaat atttccaaag attgttcatc atttcctcga
     2101 agaaataccc gaggactttt cgcttttgtg tacgaaaaaa gattcacagc aataaaacca
     2161 gtaaatccta attgtcggat attcttttcg attaataaca tactcaaatc attcgtaaat
     2221 ggttctgtat ctgttggacg aatagtaatg actactgcta atttatcttc cgcttctttt
     2281 cctttgatcg cccattgtcg tttgaaaaca tagcgatggg tatgatgagg atctcgccaa
     2341 acttctgttt gtgtggtcac taattctttt tcaatcatct ctttttctcc tatgctattt
     2401 tttgttcaag cacttcaatt accattgccg ttataagtgt caatactagt tgaaaatatt
     2461 tcatattctt tctccttttt tcttcagaat ttgatgaatc gcggtaagga tatcttctaa
     2521 acatttcgca atcattctca aataatcgat cttattcatc cgttcctcca atctgactcc
     2581 aaaccaatcg tccttctacc agtaacccac gaacaaattc tcgctggctg gtaatatctg
     2641 taatgaaata aactacatag tcttttccat cttctggtgc gcaataaata taaagatgtg
     2701 tcatcactaa acgtggtaga tgaacatctt caggaagcat acccatttca atttcctctt
     2761 tttccatcgt aacggattca tagccccact cttcagaagc agtgaccagc tgtgcacact
     2821 tttccagtac ttcgatagcc gtttctaaca agtcctttcg ttcctttctt ttagatacta
     2881 gtattcttct ggtaataaca tcgtttgata ctcacccgaa tcaatggccc atattttttg
     2941 agacactgat ttcaaacgaa gcttaggtga aatcagatac tcttttcttt cttccggttc
     3001 ttcttgacga tgaaccaact tttgatttcc tttttccgta gaaaattcaa aaatttgaag
     3061 atagtctaaa ggaaattgct tttgaacgtt ttgatcgatt agattccaac ataaagcttg
     3121 taattccacc ggcaaactgt ccattactcc ctttgtgaca taacgttatc ctttattttg
     3181 aaacatttct tttccctcct ttgccataaa aatagcccaa tcttctatta aagaagattg
     3241 ggcttcatgg atataatata tatttgtaaa taaagttaat tcagttataa ttatcaaaac
     3301 tacacaatta ttaaagtttt tcatatctct ttgtttagta agtttttcta aatcttaacc
     3361 cgtggtgcta gttaattttt tcctagagga aaatgtctaa acatgttggt aaatcaacaa
     3421 aaaaacgcat atagtagtct caaaactccc aagaaatgag gactatttaa caaactacga
     3481 tggttacgtc gtgacaactg aacattttga cttagccaat cctgttacta aagtcgatga
     3541 tatccccgat tatgaaatgt acagtcaaac aatcgatagc ttaaataagc gttttggcaa
     3601 tcgtgtttta aaaggcatca aaatcggtta catcgcttct gaaaaggatc ggatcatcga
     3661 ctatttagcc gataaagatt acgatttaaa attactcagt gtgcatcata atgggcaatt
     3721 tgattattta gatgacgaag tcaaagatat ggatcctgct attgtgattc ctcagtattt
     3781 tgcacaactt tcagaagcac tagttgttat agaagcagat gtctttgctc attttgacta
     3841 tggttttcgg gtatttggtc tatccgttgc tgaatttaaa caatatgaag cgcagttttt
     3901 accgattcta gatcaagtaa tcaaaaataa attggcattc gaattaaatg ctaagagcgc
     3961 ttacttgtat gacaatttag cgttatatga atatgtcatc gatttatatc tttcacgtgg
     4021 tggtaccttg tttagtgttg gatcagatgg gcattacctt gaacatttcc gtttccattt
     4081 cgatgatctt tttgctctgt taaaagcaaa tggtgtgacg gaattagcga tttatcaaaa
     4141 aggaaagcga attatggttc cattaccagt ctaaaaaaac gtcctcagca tcaaaagtga
     4201 ggacgttttt ttagatttct ttttctaaaa tcggacaaat acgatcttgt tttcctaaag
     4261 gaaaatgttt gatcccgatt tttttaaatc catgacgttc ataaaaacga atacctgcat
     4321 gatttttttc ataaacagtc aaacgtaaat aacgtttttg tttcgtttta gcataacgat
     4381 tcgcttcatc gagtaaccgt tgccctaacc ctttgttttg ataatctttg agcagataga
     4441 gccgttgaat ctctatagca tctttttcat cattgacttt catataacca atgagtattt
     4501 gatgatcctt aataccaata aatttactgg ttgactgtgc caattctact gccaatattt
     4561 cagttgtcaa ttgtgtctgt aaatatcctt gcatatcaag tggatctgcg ccatcgataa
     4621 acgattcata aaaactgaca acacttacaa cttgtaaagc atctagatca tcataatcta
     4681 aatacgctag tgtgatttga ttgttcatct aactcctcct tttgacatag tatactataa
     4741 at
//
LOCUS       DAYYEF010000107         4735 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000107 DAYYEF010000000
VERSION     DAYYEF010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.113"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            62..1150
                     /locus_tag="ACHA1B_002757"
     CDS             62..1150
                     /locus_tag="ACHA1B_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703466.1"
                     /translation="MYSKNWKKKLVMGVMVGSIFVFAGCSASTDKSKTATSETKTAEV
                     VKSKMKQIEKNVEKILAEKDKDTKLSEYKKFVTESSAYSKSDKTEKKITNTYTESIKK
                     IKTNFKEQDDKDLKENTLDNLEEATENDLSQKVNTLDELKKWVQKESTDVYSQAEVDS
                     LIKKIDDTITTYKNQLEKIKIDNQEATSTETTTESSEVATLQENVSEEPQVVHTNLLN
                     SIEEAAQYLGQKLPQSGGSDAFENGQQNSDGSFTFHYQLHGGPEGITWNIITVNNNGE
                     IIQDDYFKTVPNEATNNNVSTLSQAAISELEAAQLAIAKHNELGRPNATDAGSETTAD
                     GYYFYYMADGTDQMYKYFVSNSGQVQAE"
     gene            complement(1607..1774)
                     /locus_tag="ACHA1B_002758"
     CDS             complement(1607..1774)
                     /locus_tag="ACHA1B_002758"
                     /inference="COORDINATES: protein motif:HMM:NF012372.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HFM8703467.1"
                     /translation="MSIREIVRIQSFPDSYIFVGSSLSAKYKVIGNAVLPKLAKVIGD
                     SIVKQLSESNF"
     gene            1819..2241
                     /locus_tag="ACHA1B_002759"
                     /pseudo
     CDS             1819..2241
                     /locus_tag="ACHA1B_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3018..3213)
                     /locus_tag="ACHA1B_002760"
                     /pseudo
     CDS             complement(3018..3213)
                     /locus_tag="ACHA1B_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
     gene            3562..4647
                     /gene="xerS"
                     /locus_tag="ACHA1B_002761"
     CDS             3562..4647
                     /gene="xerS"
                     /locus_tag="ACHA1B_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HFM8703468.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
BASE COUNT         1804 a          724 c          728 g         1479 t
ORIGIN      
        1 aatataacca cttttatgaa aagatgttat aattaactaa aaaataatag ggagaaaaca
       61 catgtactca aagaattgga aaaaaaagtt agtgatgggt gttatggtag ggtctatttt
      121 tgtttttgca ggttgttcag cttcgacaga caaaagtaaa acggctactt cagaaacaaa
      181 aactgctgaa gtagtaaaaa gtaaaatgaa acaaatagaa aaaaatgtag agaaaatttt
      241 agccgaaaaa gataaagata caaaactgtc ggagtacaaa aaatttgtta ctgaatccag
      301 tgcttactct aagtcagata aaacggagaa aaaaattact aatacctata cagaatctat
      361 taagaagatc aaaacaaatt ttaaagaaca agacgataaa gacttaaaag agaatacact
      421 agataatctt gaagaagcaa ctgaaaatga tctttctcaa aaagtaaata cattagatga
      481 actcaaaaaa tgggtacaaa aagagagtac tgatgtatat agccaagcgg aagtagattc
      541 attaatcaaa aaaattgacg atacaattac cacatataaa aaccaactag agaaaataaa
      601 aattgataat caggaggcta catcaacaga gactacaaca gaaagtagtg aggtagctac
      661 tttacaagaa aatgtttccg aagaaccaca agtggtccac acgaatttat taaattctat
      721 tgaagaagca gctcaatatc tgggacaaaa acttccacaa tcgggcggtt cagatgcatt
      781 tgaaaatggg caacaaaatt ctgatggctc gtttactttt cattatcaac tacatggagg
      841 tccagaaggt atcacttgga atatcattac agtgaataat aatggtgaga ttatccaaga
      901 tgattatttc aaaactgtac ccaatgaagc aacaaacaat aatgtctcta cacttagtca
      961 agcagctatt tcagagttag aagctgctca acttgcaata gctaaacaca atgagttagg
     1021 tagacctaat gcaactgatg ccggaagcga aactacagca gacggatatt atttttatta
     1081 tatggccgat ggaactgatc agatgtataa atattttgta agtaattctg gtcaagttca
     1141 agcagaataa cattgagtta taatgatatt atcagatgaa ctgtatcata aatttttaac
     1201 gtgaaatgtt tgtaatatca attggagaat ggtatatgga tttactaaaa gataataact
     1261 gttatttttt agtaaattca tactatttag aaaagaataa tttgctgaat acttgtaaac
     1321 tatgtgtgat acttatctta tatggatata gactcgtggt gctagttaat ttcagcttat
     1381 tataaaccaa cattttcatt ttataaaaac gactaaaaac agaatttctg agtaaaattt
     1441 caaaagtaaa aatagtgata ttatgctctt gttcctagat tcaataatta actagcacca
     1501 cgagtttata aaattggcaa taaaatttta atcattatta acataacctg gatctgtaaa
     1561 gcaatttaac tcttaataaa aaagcatcta aaaaaagcgt gttcagctaa aagtttgatt
     1621 cagaaagttg tttaactata gaatcaccaa ttacttttgc aagttttggt agaacagcat
     1681 taccaattac tttatatttt gctgaaagag agctaccgac aaaaatataa ctatctggaa
     1741 atgactgaat tctcactatc tctcttatcg acactcttag atgaactcaa aaaaatgggt
     1801 acaaaaagag aatactgatg tatatagtca actagaaata tcgctcatag agtgcgtgtt
     1861 cgaggtcgaa aagaaatctg tgaggagttc aaattgattt accatgcgaa ttcaaaagaa
     1921 gaggcattga attacatcga ttttatgatt aggaaatgga aaaagcagga tcgaagagtc
     1981 gtgaacctac tcttgaatcc tgccctatta accttttata atttccctta cgctatcaga
     2041 cgaacaattt attcaacgaa cctgattgaa ggctttaata agcagctaaa acgatatact
     2101 cgaagaaaag aacaattccc taatgaagaa tctctctaga gattcttagc ttcgcaattc
     2161 aactaatata accagaaatt tttaagtaga gttcacaaaa gatttaaaga aattcaagat
     2221 acattagagt cgatgattta actgtaatta acagaatgga ttttccattt acacataatt
     2281 cttgacgcta cctcataata attaagagct ttaaaattag tatttattag atacttaaaa
     2341 gctattttag tattgataaa ttgttaccag caacaaaaaa gaagttactt agtgctaact
     2401 tttgagcaac tgctagagga ggtaggatat ggctaattat cctgtaattt ttattgtatt
     2461 ttctagaaat gtaattattc tcttaaacat tccagcatat ccaagtatat agaaaattta
     2521 cgttttctat atagttggat gtttacaagt tatatctggt ttaataagtt tttttctgtt
     2581 agtcatggca tgttttattg tgctggttca tcaatatatt gaaatgtact aaaatgaaat
     2641 tttcagttat ggtataatat ttatgctgtc tgctaccccg gcctattatg gcaaggggag
     2701 gaggttgtat tatgaattac cttttcgata tgttttttgc aatcttagca gaagtatccg
     2761 cgcattacat ctgtaaatgg cttgattgca aaattattgc caaaaaagac agtaagccta
     2821 cccgttaatc tgaatagaac gtaaaagaaa accactagcc cgccagctag tggtttttgg
     2881 tgtatcatga attacctttt cgttaaaaca attataccat atttcctaaa aaatacaatt
     2941 aatagacgaa ttatcattac cactttgatg aaaaaagctg acataaattt ttcttttatt
     3001 tttataatga ataaacattt atcaataagc ttttgaaagg caggatcgta ctttgttgat
     3061 gattgagata ttgctacatc aatctcagca gttaagattt ttttgaattg ttgcttgaat
     3121 tttttcttta tctaaaaaaa ttgtatctcc aggatgcaac ccattttctt taagaaattc
     3181 cttttaaatt gttaatacta ctgagtgccc cacttctctg aattttcttt aacttctccc
     3241 tccccttttt tatttgtata tacattcata tacgcttgtt aatatcaaat caaccgtagt
     3301 ctctcttatg tctaattata tagaaagatt gttctttcta tataatttag acaatttaaa
     3361 aaattaagat tgcctccttc tgtttccttt cctattcatg tataccattt attttaaatt
     3421 attaaatcta tacctattta tctgcttttt tgaaataaat taataaattt cagagtatac
     3481 caattgacaa aacactctat aattggtata gtccaattat agagatactc ctctccccta
     3541 cttatcgaaa ggatgaataa catgaaaaat acagaaatat atcaaaaaat agatacaatc
     3601 atacttcata tgcccgatta tataaaagat tttgttcaag atcgtgagga taaagatcaa
     3661 tcacctcgaa ctactttaga atatctaaaa aattataagc tcttttatga atggcttctg
     3721 agtgagtcta tcgttcccga tacttcaatc acctcgataa gacagttaac tgcctatgat
     3781 ctaaacttgt acaaatctca tttgaaacgt cgcacaaagg aaaatgtaaa aaaagagaca
     3841 acaaaaacta agctcaaaga taataataac ttaggtctat ctacttctac tatcaataga
     3901 aatatcacag cattaaaggt tctatttaaa tatctttcga aaagttccaa taatccttta
     3961 ggaaaaccat acttagaaaa taatcctatg gatcaagtag caactatcac agataaaact
     4021 acgttagctg cccgtgcaaa cgcaatcgag aaaaaattat ttctagacga agatacacaa
     4081 aattatctag attatattgc caatgaatat aaaaaaactt tgagcaaacg agctttgatc
     4141 tattatcaac gagatgtaga aagagacctg gcgatcaatg cattgatttt aggatctgga
     4201 ttaagactct ccgaggttgt aaatattaat ttagaggacc tatctttaga aaagaataat
     4261 gtggtagtaa ctagaaaagg aaataagaga gacgcagtaa atatagcagc atttgcaatg
     4321 gaatatttag ctaattatct agctattcgg aaagaacgat acaaagtaac agaaaacgaa
     4381 aaagctttat ttctagcaat ttatcaagga gaagccaagc gtatatccgg tattgcaatc
     4441 gaacggatgg tagcaaaata ttcaaaagga ttcagagtcc aagtcagtcc acataaatta
     4501 cgtcatactt tggctactag actctatcaa cagacaaatt cattggtatt aactgcccaa
     4561 caattgggac atacaagtac aaatacaaca actttatata ctcatataga caatgcagct
     4621 acaattgatg ctttgaacgc tttgtaaatg tagtaaaaaa tagtataata atgaagcctg
     4681 tctctaaaat tagataaaag cccaacttta aaggcaagct tcattatcat tttta
//
LOCUS       DAYYEF010000108         4590 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000108 DAYYEF010000000
VERSION     DAYYEF010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.114"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            186..2855
                     /locus_tag="ACHA1B_002762"
     CDS             186..2855
                     /locus_tag="ACHA1B_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HFM8703469.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3560)
                     /locus_tag="ACHA1B_002763"
     CDS             complement(2946..3560)
                     /locus_tag="ACHA1B_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HFM8703470.1"
                     /translation="MINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKAMH
                     MVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPGIE
                     KRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTIIK
                     ITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="ACHA1B_002764"
     CDS             3680..4219
                     /locus_tag="ACHA1B_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703471.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="ACHA1B_002765"
     CDS             4216..4554
                     /locus_tag="ACHA1B_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA];
                     GO_process: GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HFM8703472.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1420 a          790 c          860 g         1520 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgacatt
//
LOCUS       DAYYEF010000109         4461 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000109 DAYYEF010000000
VERSION     DAYYEF010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.115"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            574..1008
                     /gene="bacA"
                     /locus_tag="ACHA1B_002766"
     CDS             574..1008
                     /gene="bacA"
                     /locus_tag="ACHA1B_002766"
                     /inference="COORDINATES: protein motif:HMM:NF041453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin 51 precursor BacA"
                     /protein_id="HFM8703473.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="ACHA1B_002767"
     CDS             2298..3221
                     /locus_tag="ACHA1B_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFM8703474.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="ACHA1B_002768"
     CDS             3237..3776
                     /locus_tag="ACHA1B_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFM8703475.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1664 a          667 c          758 g         1372 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattga attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagaaacg gataaataat aaaaaagact
      181 gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tataaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacaatcca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttta cctagaccaa ttaaaaatca caaagtgagc ccctgtatcg gttgatacaa
      421 gggctacttg gcatactgta cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct cttataagtg ggatttttac cacgttgaga gaaaatggtc aagaacctgg
     4261 gaggcggaga aaacatacca agcaccacaa gcaaaaaaag ttagagtaac ttccaaaaaa
     4321 gaaaaatttt ttagaacaac ttttgaaaat ttaattttga tttatatccg ttcaatttaa
     4381 acatttgata aactgaaggc tagtatttaa aatgtgtata caagtggtag cgttaaaaaa
     4441 agtggaggta taacctatgt t
//
LOCUS       DAYYEF010000110         4451 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000110 DAYYEF010000000
VERSION     DAYYEF010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.116"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..618)
                     /locus_tag="ACHA1B_002769"
     CDS             complement(<1..618)
                     /locus_tag="ACHA1B_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA];
                     GO_function: GO:0005515 - protein binding [Evidence IEA];
                     GO_process: GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HFM8703476.1"
                     /translation="MTGRNPKVFISYSWENKENKEWARELADKLLENGIDAYIDQYDL
                     SLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAELLSGKNERK
                     FIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKPALGDIPRH
                     IKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFR"
     gene            complement(1161..1574)
                     /locus_tag="ACHA1B_002770"
     CDS             complement(1161..1574)
                     /locus_tag="ACHA1B_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HFM8703477.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            complement(1571..1807)
                     /locus_tag="ACHA1B_002771"
     CDS             complement(1571..1807)
                     /locus_tag="ACHA1B_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HFM8703478.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            complement(2162..2764)
                     /locus_tag="ACHA1B_002772"
     CDS             complement(2162..2764)
                     /locus_tag="ACHA1B_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbiJ-NTD4 domain-containing protein"
                     /protein_id="HFM8703479.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            3836..4048
                     /locus_tag="ACHA1B_002773"
     CDS             3836..4048
                     /locus_tag="ACHA1B_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8703480.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            4038..4433
                     /locus_tag="ACHA1B_002774"
     CDS             4038..4433
                     /locus_tag="ACHA1B_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703481.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
BASE COUNT         1481 a          734 c          608 g         1628 t
ORIGIN      
        1 tctaaatgga attttatata atgcagaacc ccttgagcca tccattttag gtacagttac
       61 tttatcagtg ataattccta agatttcaat atctttattt tcattatgtt ctataggtag
      121 taaaggactg cctttaatat gcctaggtat atcacctaat gctggttttc tcttaacacc
      181 aaatatagtt gtaattaaat catctaagtt ttcatcataa tgctggctat ctgataaatc
      241 aattccaagc tttccagcaa gaaaagtagg aagtacttcg cttgcacgtc cttctttaat
      301 tattgggata aatttacgtt cattttttcc agaaagcaat tctgctgaga taatatgacc
      361 ttcataccca acaccacttg tacgattatt tgcctttttt ttatactctg gtgtacatat
      421 aattagaaca taatctgaat cggatatttg ctgctccata aactgaggta atctatcacc
      481 taaacttaaa tcatactgat ctatatatgc atcaataccg ttttcaagta atttgtctgc
      541 tagttctcta gcccattctt tattttcctt attctcccat gaatatgata taaatacttt
      601 gggatttcta ccagtcatct tgttctcact attcctttcc atcactaatc taagtgctaa
      661 ctatttggta atacattaca attatatcac tcaacaagtt aataaatttt aattcaggaa
      721 aattcatcaa aattattttc aagcgtattc tcagctaaaa tgaacttgga taaactctta
      781 atttagtgat tttcaccgaa ttaaaaaaat gaatccgaag ttgaaaataa gtcttcctac
      841 tttatcgtgt acagtacgtt agacattaat tgattaaaag aagagcagta gaccaggaat
      901 taaatataaa ttatcatttg atcagataat cattctagct tctttgaaaa tagatagtca
      961 ttagttttgg agagagtaga gtattacata acatgcttgc ttaagcgatt aaggtcattg
     1021 gtttacataa ataaattggt attataaaaa agtttattat ttaagctttt aaaataatga
     1081 acttcgcata atgtatctta tgtaaactaa aataaagaac aaactaaatc ttcagattta
     1141 actgaatccc tagtttgctt ctactttttt gaatcggtct ttgttgaatt cttttttagt
     1201 atatctgttg ttgcctcttt taagtcatca aaatcaccct gatacgtagc aatttcaact
     1261 acaaattcta ctacttcctg atttttcatt tttagtgaat agccatttag cttgagaaaa
     1321 acatacgcgg ctaaaaatgc tgtacgtttg ttagcattat gaaatggatg ctttttgatc
     1381 agatttatta gcagaacagc tgctttgcta aatttatcag gatacagatc ttttccaaaa
     1441 atatgctgtt taggttgatt tacagccata ctcagcgcat ttttgtcaat gactccgatt
     1501 gtttctcgcg gtgaatattt ctttatttga ataacattca attttacaat atctttttca
     1561 cttagataga tcatttttca actaattcct tgaaagctgc atcatactca gataaagctt
     1621 ggttaacata catatcaatt tcaagatcta tcttgctttc ctcttttaca atagcttcca
     1681 tcattttatc ttcatcaata aaaatagtat ctccaggttt caaacctttt tgcaataaac
     1741 tctcttttga caaagttaca actattgaat tacctacttc tctgattttg cgttttttaa
     1801 tattcatatc atcaactcct acgataagta tacaccgtat atccgtattg ttcaatcacc
     1861 cttattactt ccttcaatta ctaaactttt aaagagttgg aaattaatag ttataatgta
     1921 gctcttggat gaattttaac ttttcatgat ttattggagt catatgctat ttttactccc
     1981 aaataattaa ttacggctga acatgttgtt aacaccaaaa ctgcatcagg taaatctgag
     2041 acaattgttt tttcattttc tgcatgtcgt attccattat tactcgccaa accatacatt
     2101 gtctcaaatg gttttaaaaa tgtaagatcg acattgttat tcgatttgtc tttaattgct
     2161 tttatagcag ttcccaaagt atttttttat tagctggtaa tcctgaaaat tcgataagac
     2221 aactttcgac agcactaatt gcttctctca ctacagtatt ataatcttga ttttccttct
     2281 cgcttatata tgtaagagat ttatggatat gattttttgc gtaattaaat ggtgattcag
     2341 atacagcatt tatagactta atagaaatat catctgtgat tggaataaat tcattgcttt
     2401 cgcttaatct gtaaccagaa ttttccgact ccagaatttt atttacttcc tctcttttct
     2461 ttttatccaa gattttagca cttgcaaaaa cctctaataa atcataataa gcataccact
     2521 ccaagtcttc taacctcttg ataatatctt cataataaac agtaaaatga taacccaact
     2581 catagctatt atttatctgt tctttaaaaa actctttaat taaaaaagaa tatattaccc
     2641 atgagacttt tccattataa ttactataaa ctttatcagc ctctcgtaat atatcataaa
     2701 tcacatttgc taaactattt ttaagagggt ctgtcaatct atctctcagt atgatatcct
     2761 ccatttttta aaaccaaatc tttcagaaaa aagcattgca ctacctccag taaattaact
     2821 tatactcata taactttacg aagcaataat tattcgtgtt gttttacata aataaaatga
     2881 aatatctgtt aagattgttt aatggcacaa acataaatta ttatataatt acgtattaat
     2941 ttatctagat ctattaataa tactgatccc taataggtgt aaaacagtta taagaaatga
     3001 gtactctagt atttgtgtta cccgaataat tacttgatta tattggtttc ccatataatt
     3061 gaaggctgtc ctaattttta cctactatat gatcataatt gattaactct tatatatttc
     3121 cgaaaattat cttgaagatt tctattggta tggagaatat ccatttcatt gccaataagg
     3181 atataaattc tcaaaataac aatcgatgtc tgtattaaac aagcctagaa tggtaaatct
     3241 gattcgccaa aaccattgga ttgtatcgat ttgctttacg cgaacgccac ctacccattt
     3301 tataaaaata aaatgggcaa aagatctttc tttttgtcat acaaaaagaa gaaaaaaaag
     3361 agacgatttt cttcttccaa aatcgtccct cttttttcta aaaccatgga tgaacgaaca
     3421 aaaaatctct cgtattttgt ttgttcatcc actaaaaata tgcgaacagt atggtttcat
     3481 tcaatcctgt tcttacaagt caaaagcatc gaatcgtcct tggacgattc aacaaaaaaa
     3541 gtagtcgttt ttggatgact actaagttct aaacattcat tacccaaaat caatttggtc
     3601 taacatcgtt tctcgactgg cttgatctaa tcggctcttg acagggcttt ttcttttctg
     3661 ttgatagcag ataagaggaa ataagaataa gtgtgttcat gtgtcataaa aacagtaact
     3721 aaaacattaa aatcaaaatt tatatggaaa gcttccttga cattttgtgc tcgcaggagt
     3781 attataaaag cacgaaagga aagtaaactt tccatttttt agaaaggagc atgttgtgaa
     3841 aaatcgtttg gaagaattac gaaaacaaag aggaattaaa caagaagatt tagcttctgc
     3901 tcttgaagta tctcgtcaaa caataggttc tttagaaaat ggacgttata atccctctat
     3961 tatattggca tttaaaattg caaggtactt tcaaatgagc attgaagaaa tttttatcta
     4021 tgaggaggaa agtgaagatg aaaaataagg gtcagatttg gtatatcggt tatattgttt
     4081 cgttgttttt gattgtgaca attttggtta cagattttcc taaaatggta gatattggac
     4141 ttgctatttt attcagtgcc gtttttggcg tttctcatgt tcaaattttg catgataaaa
     4201 tgattaaaaa tgatgcagac tacaaaatca atgttatgga cgaacggaat atcataatca
     4261 aagaaaaagc gggaaatata acaaatatgt ttaacacaat actgttaggg gtggcaacag
     4321 ttatatttat ttgtttagac tacatcattc cagctattat tgtcggaagt atcattgcaa
     4381 tccagccgat tattttaatc attatcagta gtgtgcttga gaaaaaaatg tagaaataaa
     4441 ggttcataca a
//
LOCUS       DAYYEF010000111         4450 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000111 DAYYEF010000000
VERSION     DAYYEF010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4450
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.117"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            153..1859
                     /gene="efbA"
                     /locus_tag="ACHA1B_002775"
     CDS             153..1859
                     /gene="efbA"
                     /locus_tag="ACHA1B_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HFM8703482.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            complement(2017..2919)
                     /locus_tag="ACHA1B_002776"
     CDS             complement(2017..2919)
                     /locus_tag="ACHA1B_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFM8703483.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(2916..3608)
                     /locus_tag="ACHA1B_002777"
     CDS             complement(2916..3608)
                     /locus_tag="ACHA1B_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HFM8703484.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            complement(3651..4292)
                     /locus_tag="ACHA1B_002778"
     CDS             complement(3651..4292)
                     /locus_tag="ACHA1B_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbR-like 5'-deoxynucleotidase"
                     /protein_id="HFM8703485.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
BASE COUNT         1377 a          948 c          768 g         1357 t
ORIGIN      
        1 taaaaatttg gatttcaacg atagaaacac tgttttttat gtaattagtc caagattttt
       61 ctagactttt gctttactat tcggccaaat tggtttttct tctttttttc gttataatga
      121 atatacttat gaaaagaaat gaggaatgaa ccatgtcctt tgatggtgta tttacccacg
      181 cgatggtcaa cgaattgcgt gaaacgttac tatctggccg gatctcgaaa atccatcagc
      241 cttatgaaaa tgaaatcgtg ctggtgattc gttcacgcgg caaaaaccat cgattattat
      301 tatctgcgca cccaagttat gctcgtgtac agattaccca aatcgattat cagaatcctg
      361 ataatccgcc taacttcgtg atgatgcttc gaaaatattt ggatggcgct attttagaag
      421 acatcgaaca aatcgaaaat gatcgagtga tccatttcca ctttgctaaa cgaaacgagt
      481 tgggtgatct acaaaatatc atattgatcg ttgaattaat gggacgtcat agtacgatcg
      541 tcttagttaa tcgagaaact ggaaaaatac tggatgcgat caaacacatt ggaagctctc
      601 aaaacactta tcgttctttg cttcctggtg tagaatatgt tgctccgcca aaacaagagg
      661 tcttgaaccc atttagctcc gagaaagaaa aaatctttca gcggctttcc caaactgaac
      721 tagatccaaa agcaatccaa cgtcagtttc agggaatcgg tttcgatatc gctcaagagc
      781 tgaccaaaag attactggaa cgtcctaatg aaaagatggt tgtatgggac gaatttttct
      841 cagccatcag ccatcagcct attcctactt tttacgaaac ggaaaataaa gattttttca
      901 caccgattgc ttatcaggta ttgtccgaac aggcatctgc tgtaacagct tatccaacac
      961 tcagtcaatt attagatagc tattatcacg aaaaagcaga gaaagatcgg gcaaaacaac
     1021 aaggcggaga actgattcga aaaatcgaaa atgaactaaa acgaaataaa aataaattga
     1081 aaaaacgtga acaaacactc aaagaatccg aaaacgctga gaattaccgt agaaatggcg
     1141 aactacttac tacttttctg acacaagtac cacgcggcgc aaaagaagtt gttttaccta
     1201 attattatga agaagatcgg ccaatcaaaa tagcactaga tccggcattg acaccaaatc
     1261 aaaatgcaca gaaatatttc catcgatacc aaaagctgaa gaacgctgtt aagctgattg
     1321 gcgaacaaat ccaagaagcc aaagatgaaa tccaatatct tgaatctgtc ttatctcaac
     1381 tggaaattgc cggcccaatg gatatcgaag caattaaaga agaattgact tcagaaggat
     1441 acctgaaaaa gaagaactta aaaaaacaaa aacgtaagaa accatctcag cctgatcaat
     1501 acttttcttc tgacggaacg ctcattcttg ttggtaaaaa caatcttcaa aatgaccagc
     1561 tgacaatgaa gacagctaaa aaaaccgact attggcttca tgcaaaaaat atacccggtt
     1621 cgcacgtcat cattaaaagt gacaagccct cagatgaaac aattacagaa gctgccgagt
     1681 tagctgccta tttttcaaaa taccgatact ctgcccaagt gccggttgat cttgtacagg
     1741 taaagcatat ccgaaaacca aatggcgcca agcctggtta tgttatttat gaaaaccaaa
     1801 agacgattat cgtgacacca gaagaagaaa aaattacagc tatgaaacaa aacaggtaat
     1861 caatgagtgt ttctagaatc atatttgcgt actttcccac aacagcaatt agttataaat
     1921 tgtttgctac aaaaagagga gttgtgacaa aattctgtca caacccctct tttttgatca
     1981 acggtgttca ataaacagcg ttctcatctg cttttcttag ctctgctggt ccagtaaccg
     2041 agtaagctct ttgataaatc tttgagcgat ttcactgagc ggacgtttcg ccgaataaat
     2101 gatataaaat tcatttagtt cgccttctgc caaagggatt aaccgcaagt gctcgcgaat
     2161 ccctccaatc acaataccag atcctgaagc gtaagcatca gtttcaagaa cgatattcat
     2221 caaagtacct cgatcactcg tataaatcac tgtttcttga tcagggatct cgataaggtc
     2281 ttcataaaaa tacgggaaat tatttccatc ctgtgtaaaa cgaacttgag gataagataa
     2341 caattcttct ttggtgatct ctgcgtgttc agctaatgga tgtccttgcc ttaaaaaaat
     2401 atgcgttttg aattttccaa tgctgcggcc acttagctct ccttgttgta aatatcttct
     2461 gataccagct tgattatgct cattcatata aataatgccg atctcactgt gctgctcttt
     2521 gacttcttcg atcactctcg ctgttgtcgt ctccatgatc cgaaattgtt tgatctcgtc
     2581 tttgaattcc tcgagtagct gtgcggtcaa aggacctaag aaatcataat gctgggcagc
     2641 gatcgaaaaa ttgtctctct tttcactcgt tagatagtga gtttctaatg tatcaagctg
     2701 gaccaatatt ttctcggcac gatttaagaa gtcttgccct tcttctgtta aatatgcccc
     2761 tcgattcgtt cgagtaaaca gcgtgatccc taactcggtt tctaattctt tgataccagc
     2821 tgaaagactt ggctgggaga caaacatttt ctttgccgct tctctgaaac taccattgtt
     2881 tgctacagcg accacgtatt tcatctgctg aatattcatt gctcaaactc ctcgaaataa
     2941 taaatttctc ttccattcaa gggctggatt ggtcggttgt tcggtcgagc atactgacca
     3001 tcgaagggga gaagaaactc ttggttcagt tttcctacat gatccattac aaaccattgg
     3061 attggcccgc tggtaggcgg agttgtcaat gagccaatat aatggaaatg gcttttttgc
     3121 tccggaaaga acacatccgg atttacccaa tgctcatgtt tttctaagtt ccaactttcc
     3181 ccattttctt gattatacag ccaaccttcc tgtaccatta gctggtacat gacacccaca
     3241 actagattct cttttttgct gttcatatga acaaaatgaa attcaatatc ttcctgtttt
     3301 ccgttgatga tatgttcaga aggcaagtgg aaatgaatat ctgtcaaata atagcgttct
     3361 ttcttgaact ctacataact gagttggtca aaaggtacta aatgaatcgt gtttttgaat
     3421 tccttgtcag taaaccgttg cttttgataa tgaaaggaaa gcgtgtctcc ttctattttg
     3481 gtttcttccc ccttggtcaa atgaataggc gactgcaatg gaaattccgc acctctcgca
     3541 aaccaatcac ataaactcgc ccaattttcc ggacctttgt ctccagaata gccccattcg
     3601 acatccatat tctttttcaa ctatacttcc ccctgcatct catatcattt ttatttttct
     3661 tctttcttta caatcgttga gacggtttct aaaaacgcct cttttccata aaattcctgg
     3721 ttcaatagtt ccggaaatat ctctttaaag aaatactgaa cagaaggccg atgttcaaag
     3781 cttttaatcg tagtcactgc ctcaatgaac atctccttat aaactttttc cgggttattt
     3841 ttgatgattt catcaaaaga ttcataaaga aggtcaacct tatctgaaat ggctaatagt
     3901 tctccttcta cggtttcatc ttttccttcg aacaaccgac ggcgataaac ttcttggaac
     3961 tcagctggaa tctcttggtt gatgaattcg tccgtcatct tttcttcaac tgtttgcagc
     4021 atccctctta actctttgct tgcgtatttc accggcgttt tgatatcacc aataaaacgc
     4081 tctgtgtagt catgattcaa tgatttttca tagagcagtt tccaatcgat cggttgtcca
     4141 ttcgcttctt caatgtctcc tagaacttgc gcaatagatg ctacacgata cgaatgtgct
     4201 gcaactgtat gctctgtata tttaaaaaat ccaggtgccc ttgtgatcgt ctctaaattg
     4261 ttcaatccta aaataaattc attcaacccc ataaaagtta cctccctttg agatttcttt
     4321 ttccgaatat catatcatta aataactgat attcgcaaca tttccgctct ttaccatttt
     4381 tgaaacagct cccttaccaa aaaatagaga aaatctatat ataatagaaa aaagagaaga
     4441 gattattctc
//
LOCUS       DAYYEF010000112         4430 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000112 DAYYEF010000000
VERSION     DAYYEF010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.118"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(543..2048)
                     /locus_tag="ACHA1B_002779"
     CDS             complement(543..2048)
                     /locus_tag="ACHA1B_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HFM8703486.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="ACHA1B_002780"
     CDS             complement(2045..2731)
                     /locus_tag="ACHA1B_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HFM8703487.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACHA1B_002781"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ACHA1B_002781"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HFM8703488.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1238 a          919 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DAYYEF010000113         4305 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000113 DAYYEF010000000
VERSION     DAYYEF010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.119"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            148..1137
                     /locus_tag="ACHA1B_002782"
     CDS             148..1137
                     /locus_tag="ACHA1B_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HFM8703489.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1134..1553
                     /locus_tag="ACHA1B_002783"
     CDS             1134..1553
                     /locus_tag="ACHA1B_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703490.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1562..1870
                     /locus_tag="ACHA1B_002784"
     CDS             1562..1870
                     /locus_tag="ACHA1B_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703491.1"
                     /translation="MDKIDLREETVNRIEVMYERLADYLNLSDEDNYSEMLERMMDVL
                     NSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQISVINSKEKGM
                     "
     gene            1874..2236
                     /locus_tag="ACHA1B_002785"
     CDS             1874..2236
                     /locus_tag="ACHA1B_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703492.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVGNELRADEKSAPSERNYPNESDGIFGGIPNRK
                     SQMSESGFASMFSDVNSR"
     gene            2458..3864
                     /locus_tag="ACHA1B_002786"
     CDS             2458..3864
                     /locus_tag="ACHA1B_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HFM8703493.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQINIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKMEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     VSPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYICRQREE
                     NEREKALVASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVAALEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
BASE COUNT         1497 a          602 c          996 g         1210 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt attttatagt tttaattgac tagaaaaaaa
       61 ctaaactaga aaggagagca atctattttt tgttatcggc ttttcagcct tttttgtata
      121 caaaatttgt agattcagta tagcaagatg aaaaagaaaa agcaagattt gattaacgga
      181 acatttcgag aaaaaaagaa aaatttgaaa aaagtggtgg catttagtga taatcgaatt
      241 tctcccaaaa tgcgtgaatt gatgacaggc tgtggttcat atttagaatt tattgcaacg
      301 attgataagg agaaaaagaa attggtccaa gctcactttt gtaaaaatcg tttctgtccg
      361 ttatgtgctt ggcgtaaagc tcgtaaggat tcgatgatgt tgtcgattat gatgcaagct
      421 attgcggaag aaaagcagta tcaatttatt tttatgacgt tgacgacacc gaatgtaaaa
      481 gcggaatgtt tgaacgatga aattgatttg tttaatcatg cattgaaaaa gatgtttatg
      541 cgcaaacggg ttaagacttc gattaaaggc tatgtgcgaa aattggaaat cacgtacaac
      601 aaaaaacgga atgactataa cccgcatttt cacttgattt tggcagtaaa taaatcttat
      661 ttcacggata aagattatta tatcaagcaa tcggaatggt tagatttgtg gcgggaagtg
      721 accggaaaaa cgggaattaa tccggatggt accgacgaaa ttacccagtt ggatattcgc
      781 aaggtcaaag ggttccaaca agaaaaagca gtacaggaag ttgcgaaata ttcggcaaaa
      841 gattttgaac tgaccgaaag tcaggaagtg tttgacacat tctatcatgc aatgaaaggt
      901 cgtcagttga ttacgtttaa cggtgtattc aaagaataca agaaaaaata tgagtcgggt
      961 gaccttgatc gttataagaa aaaagatgag aatgaatatt tttggttttt gactgcttcg
     1021 tggatgagga aagaatcgaa atatgcggtt gattatcgtg agatgagtgc tgatgaaaga
     1081 aattattttt caggaatgta tgtcgatgaa aaatctgttg agggggaaaa tgaatgactg
     1141 attcaacgga taaaatgaca attaaggcgc ttgctgatga actaggaata accaaaaata
     1201 cagtgagaaa ttatctagtc aaagccggat atgatcttgc tcggtacaag aaaaatggaa
     1261 ttatcttgct agacaaagag ttgattggtg ttgctcggtc aatttatcgg tcaaaaggtg
     1321 gtcaattgac tggtcattta ccggtcaata gcacgggcag tgattttcct ttggaaaaag
     1381 agaatgagtt tttgcgtgat caattagctg agaaggacaa acatatttct gaattaacag
     1441 aaatgattcg tgatcaacaa aaattgaccc tgcttcagca acaaaaaaac gatcagttgt
     1501 tactagaaaa tcaagaatta aaaaatcgaa aatggtggca attctggaag tgagatgtga
     1561 catggataaa attgatttga gagaagaaac agtcaataga attgaagtga tgtatgaacg
     1621 gttagctgat tatttgaatc tttcggatga agataattat agtgagatgc ttgaacgaat
     1681 gatggatgtt ctcaactcgg ttatcaatgc tgatctagca aaatcttcag ttttgactaa
     1741 tgaatttgtt cataagcatt tagcgcaaac aactgatgaa gctgaaaaag aattttggtt
     1801 gaaattaatg agtcatatta tgcagttaaa ccaaatttcc gttattaatt ccaaagaaaa
     1861 ggggatgtag tttatgggaa tgactttagc agatattaaa gtgcaagaag aaaaattaaa
     1921 aaaagaacag gcgaaacttc gccaacagaa gaaacgattg attgagaaag aaaatgctgc
     1981 aatgggcaag gctcttcgca agcgttttgg gtttgaatct tttgctgatt ttgagcggtg
     2041 gctatcgtcg atttctgacg atcagcaaca cgaaaaatca gtgggtaatg agttgcgagc
     2101 tgatgaaaaa tcagcaccaa gcgaacggaa ttaccctaac gaatctgacg gaatattcgg
     2161 agggataccg aatagaaaaa gtcagatgag tgagagtgga tttgcgtcaa tgtttagtga
     2221 cgtaaattca cgataagcga atattttgca tgaagcaaaa taaagcgtaa aaggagttga
     2281 gagcgtgaca cgctttcggc tccttttttc gttgtcactt gtgacggcga aaaccctcgg
     2341 agagcgtttg gaattgtgac agtcatgtca caattaggaa aacgttactc tttgacaaag
     2401 agtaacagaa aggtttacac tctttttatt agcgacagcg cgaaggaggg gtttaacttg
     2461 gggtttagta tttcgttcaa aaagggaaca aagaatacaa gcatttctca taataatcgt
     2521 gagttaactg atagccaaaa aatcaatgac tggcataagc atattgattt cacaaaatcg
     2581 gatgaaaata tctatttgga acaaataaat attcgtgaaa aatatgaaga attattcggt
     2641 gaagccgtag aaaaatataa tgcaaagcag aaaagagccg atagaaaaat tgaggactat
     2701 ttagcaaagg ttcgcaagga taaaaaaatg gaaccacagc gagaatttat cgtgcaaatt
     2761 ggtactcttg atgattttcg tactactcgt gatgatggtt cttctactgg catatcggaa
     2821 caacaagcag aacaaaatcg agtgattgcc aacaaaattt tagttgagta tttcaaagaa
     2881 tttaaagaac ggaatcctag tttatccgtc tacaatgctg ttattcataa tgacgaagta
     2941 agtccgcacc tgcatttgaa tattgttcct gttgctgaag ggtataaacg gggtgttcaa
     3001 aagcaaccaa gttttaacaa agccttgcaa cagcagggtt tacgagcaga taaagagaat
     3061 ggtcgagtga tttggaataa ttttaggaat caggaagttg agtcaattga acgtttgatg
     3121 gcagattttg gttgggagcg tgagttagtc ggtactaaca aaatcaaaga tattcatgaa
     3181 tacaaagaaa tcatgagcga aatttccgaa ttgcgtcaaa cggccgtaaa agagcgtgag
     3241 agcgtttctg atgagttgag gtatatttgt aggcaaagag aagaaaacga gcgtgagaag
     3301 gctctggtgg cttctgagag agcgaagatt gaagaagaga agaaaaatat gctgaatgta
     3361 aaaaaagaga tggcggtcat tttccaaaaa gatatggttc ctttagaaag tttcaagagg
     3421 cttcctgatg gttcgtatca tttatctggg aatgattttg ttgatttgta tcaacgagct
     3481 acgagagcaa caaatgccaa gagaaatgct gataacatga gtgagcaata tttacagatg
     3541 cttgagcaaa atacagaatt aaatgagtat gtagctgcat tggaagaaga gcgtcatttg
     3601 tctggtagaa aacaattagc agatttacaa gtggaaaata aaaagctgaa agaagaaaat
     3661 cgctctttac gccagcgttt agagcgatta aaaaacgcat ttcaaaaatc gatcactcgt
     3721 ttgtctatcc gttttgggct tgcagaaaag gatatggggc tttctgagga attagaagta
     3781 ttagagcagg agaaaacctt attttatcgt caaaacgtct cacagcataa attagagcgt
     3841 tctgaagatg agatcgagtg gtagttacga tgtgcagtca acggtaccgg aggcggtttg
     3901 tgccgaggat aaggagttga cggctaaacc actagcctat taagctgaca tttgctaaaa
     3961 aatggcaagt ccattttttg gccaacttag cgttagcgaa gtttgggggc gcccttttta
     4021 aagggtgcgg ttttatgttt gcatgactaa gaatgagtgg gaaaatttaa cagccctatc
     4081 taacaggcgg ttaaatgtac aaaatatgta caccccctta aaaatgcagt ggtcgattga
     4141 tcgaatttta tgtctttggg ttttggggtt ttaaaacgaa aaaaaggggg cgattttcgc
     4201 cctctttttt gatgtttttt cttatcttga tactataggc aactatttct gcgaagaaat
     4261 cggggctata gtatgggtct atcccttgtg gctctaagga agaac
//
LOCUS       DAYYEF010000114         4230 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000114 DAYYEF010000000
VERSION     DAYYEF010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.120"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1019..1987
                     /locus_tag="ACHA1B_002787"
     CDS             1019..1987
                     /locus_tag="ACHA1B_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFM8703494.1"
                     /translation="MSNEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMRDVGDKKVQ
                     FTFEQLKDLSNYKATANVRFIDDLETTYDKLMDLRFGRRSADGLQRERFVLFNQFKID
                     GKSDIPFAEIQVHEKALPLLNNLEEWVRYSLQQFNELESSYSKTMFRLLKQYRTKGFA
                     YFSKEDFHELLDIPKSYNQGTIDQRVFNPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKSDDFNKHAPTKEEQNKALELANQQVQSEKAPTSLQEKIKEQKRKLELL
                     QQLEKLEREQNTQNKENNAQKSEINSDIPSELKKDLLDNLQNLFKD"
     gene            2004..2528
                     /locus_tag="ACHA1B_002788"
     CDS             2004..2528
                     /locus_tag="ACHA1B_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HFM8703495.1"
                     /translation="MTEKTIKELAEELGVSKTAINKKVSDENRKLWFSKIGNKFVINE
                     TGQKAIKSMFFNENENSNQQLVGEKTKTENHKNANQVPELEVLSLLEQQLNQKDMQLQ
                     EKDEQIKQMQKLLDHQQQLTLQANQQIEKLQEQLQLTYTEESSENKSTTLSEETESIE
                     KQSKAEKKWWQFWQ"
     gene            2904..3185
                     /locus_tag="ACHA1B_002789"
     CDS             2904..3185
                     /locus_tag="ACHA1B_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000353845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703496.1"
                     /translation="MDILVRNINPKIIARIDKRCQELTTKTGKKWSRNKYLKVLIESD
                     FDRQLMNYKKDQFDLLLEKFIAIQTENTNILNDYVHTNNQLIETLIGGI"
     gene            3187..3603
                     /locus_tag="ACHA1B_002790"
     CDS             3187..3603
                     /locus_tag="ACHA1B_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703497.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDVNNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIMAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     ENQLNPSRRNQPKNRQKETNQTFTSGNFDPTNFLKR"
BASE COUNT         1613 a          741 c          699 g         1177 t
ORIGIN      
        1 aagcggttat ttgcaccaaa tacggaggta tttggctagc aaatatagag cttgccaaac
       61 actttagtga gttttgtaga aagtaccttt aaaggtactt tcacattacg aacgatacgt
      121 ccgtaggacg tactgaaagg gtgggattta tgagcgaact aatgcaaaat ttggctagca
      181 aaaaaagtta aaaaatatat gctaataatc gagcgaaatg aacacttttt caagtgagcg
      241 aatccgccat gacaaagctg aagcagttta tttcagcttt gtcatggcgt gtgcctagac
      301 ttttaaaaaa gtcggcacac gagcaaatat ctttatcaag ctctaatttg cgttttaaga
      361 cgtttgaaac gtctaagtat ataaatatat aagagtaggt ttaagagtgc ttaaatcgaa
      421 ttttagaggg cattcagaca actttagggt tgttagggct tgccctgacc gcctgtaagg
      481 cgctttaaga acaagataag ggatttatac taagactgtc ttaaaacgtc tcaaacgaag
      541 gctcatagct tctcaaagag ttccttatga acatttttag caaaggagcc ggaagcgact
      601 gcgcagtata atgtgagagc agagcgatca caccttttta agcgactgta gggagtaaga
      661 ttcccagttg agaaaaatgc gcgaatctgt ttggagaaaa aagaagtggt tttttaggcg
      721 ggaaattttg tccccctctt ttataatctc tttttaaacc tctttttaaa cctctttacc
      781 gtcggctata tccttactct cccaagggaa tgacgctttt atctacatcg ttttgtctgt
      841 ttatctacat cgttttgtct gtttatctac atcgttttgt ctgtttatct acatcgtttt
      901 gtctgtttgt acattgaatt agtacatcga cgatgttaat ataagatgta gataaacagg
      961 cattttgtat ttcataacgt gtatctcttg tgcgagtaag aaaggagcta ttttaaatat
     1021 gtctaatgaa atcgtaaagt atcatcatga attaaataca attccgttgc gaaaatttac
     1081 accagtcgaa atgaatttgt tcttttctat cgtatcaaga atgcgtgatg taggtgataa
     1141 aaaagtacaa tttacattcg agcaattaaa agatttaagc aattataaag caactgcaaa
     1201 tgttcgattc atagatgatt tagaaacaac gtatgacaaa ttaatggatt tacgttttgg
     1261 tagaagaagt gctgacggtt tgcaacgtga acgttttgtt ttatttaatc aatttaaaat
     1321 cgacggaaaa tctgatattc cttttgctga aatacaagtt catgaaaaag ccttaccctt
     1381 acttaataat cttgaagaat gggtgcgcta ttctctccaa caattcaatg aattagaaag
     1441 cagttattca aaaacaatgt ttcgattact aaaacaatac agaaccaaag gtttcgctta
     1501 tttttcaaaa gaagactttc atgaattact tgatattcct aaaagttaca accaaggtac
     1561 gattgatcaa cgtgtgttca atccaatacg acaagaacta accgcaatct ttaaaggttt
     1621 aacaatcaaa aagaaatacg gaaaaggacg gggaaagcct gtcattggct atcaatttac
     1681 atttaaacct gagataaaaa aatcagacga ctttaacaaa catgccccaa caaaagaaga
     1741 acaaaacaaa gcattagaac tagctaacca acaagttcaa tctgaaaaag cacctacttc
     1801 attacaagaa aaaatcaaag aacaaaagcg aaaattggaa cttttacaac agttagaaaa
     1861 gttagaaaga gaacaaaata cccaaaataa agaaaataat gcacaaaaat cagagataaa
     1921 ttccgatatt ccttcagaac taaaaaaaga cttattagac aatcttcaaa acttattcaa
     1981 agattgaggg gtttttagat tttatgacag aaaaaacaat caaagaactt gctgaagaat
     2041 taggagttag taaaacagca attaacaaaa aagtttctga cgaaaatcga aaactttggt
     2101 tttcgaaaat cggaaacaag tttgtgatta atgaaaccgg acaaaaggct ataaaatcaa
     2161 tgttttttaa cgaaaacgaa aactcaaatc aacaactagt tggcgaaaaa acgaaaaccg
     2221 aaaaccacaa aaacgccaac caagttcccg aattagaagt cctttctctc ctagaacaac
     2281 agttaaatca aaaagatatg caactacaag aaaaagacga gcaaataaaa caaatgcaaa
     2341 aattactcga ccaccaacaa caactcaccc tgcaagccaa ccaacaaatc gagaaactgc
     2401 aggaacaact acagttgact tatacggaag aatcttcgga aaataaatca acgactcttt
     2461 ctgaagaaac agaatcgata gaaaaacaat caaaggcgga gaaaaaatgg tggcaattct
     2521 ggcaataaaa ccagcaattt aaattaataa aaattgctgg ttttattctt ctttttgctt
     2581 ttgcgagcag agcaacatgg acccatgttg cgatattttg gtggcgcccc aatccccgtt
     2641 ttttcgttga atcttactcg gactgcactc gttttacagc tgatttttct gaattttgaa
     2701 agagcataag gaaacgtggt atcactttct tacgaaaggt gctagatagg ctgtgcctat
     2761 cacgtttctc agaaaaaaat ttgctatcac ttttttgcca ttgtggctag gctatgtata
     2821 gtgttttggc gaaaaatagc tatacaaata ctatatttgt atggtataca taaattatac
     2881 gctgatacga aaggaaaatt tccatggaca ttttagttcg aaatatcaat cccaaaatta
     2941 ttgcaagaat agataaacgt tgtcaggaac tcacaaccaa aacgggcaaa aaatggagtc
     3001 gaaataaata tctaaaagtt ctaatcgaaa gtgattttga ccgtcaactt atgaattaca
     3061 aaaaagatca attcgattta ttactcgaaa aatttattgc cattcaaaca gaaaatacga
     3121 acatactgaa tgactatgtt cacacaaaca accaactcat tgaaacactt atcggaggaa
     3181 tataacatga gaaaaacttc tgttcaaaaa cacgtaaccc tttatcccag tcacgttgac
     3241 gttttagatt ccatcatcga aaaaaatcca gacgtcaaca attattcaga agccattcgt
     3301 tttttatgta tgagttatga acctgatacc aatacaacca caaccagtaa ccaagcaaaa
     3361 ctcaatgcca tgggaaaaga aatttctatc atgacagaaa tcatggcaga atttgctgat
     3421 ttatatctaa aagatactgg tgttcttatc ggtacaaatt ctaaagtgta tcaagaagtg
     3481 aaagaaaaaa ttgaaaatca actcaatcct tcccgacgaa atcaacccaa aaatcgtcaa
     3541 aaagaaacca atcaaacctt tacttctgga aattttgacc caacaaactt tctaaaaaga
     3601 taaaaaaaga aaccgatccc taaaaaaatt cctcgatttc tttttaggga tcagtcttcc
     3661 agcaagattt gcaagttggt accaacttgc gaaaaaaaag aaaaatccgc ttatgcaact
     3721 tcttcttttt gtattttggg gcgctacccc aatccccaag tatcggttat ttaatagcgc
     3781 ggaaatccaa agaataggac gtaccctgaa acaaaaaaag actgctctca cgagcagccc
     3841 aaaatgagat tatcctattc atcaacataa aaatattaca aagtgaagaa ctagagaaag
     3901 acaaaaaaag catatcaaat cctctcaaaa ataacaagtc tttaaaaaat gacagataaa
     3961 aatgcacaaa gaactaaaaa agagaaatcg cgtaaaatca agcattagaa gctagtaact
     4021 agctagacca attaaaaatc acaaagtgag cgtctctatc cattggtaga ggggctactt
     4081 ggtctagtcg acattatgtt aactagctcg ataaataacg attatgttcc caaaacaata
     4141 ttttatgaac tataacaaaa atttgttatc gcatattgta tattttaatt atataattat
     4201 aggtgtatac cacttaaatt taacacaaag
//
LOCUS       DAYYEF010000115         4138 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000115 DAYYEF010000000
VERSION     DAYYEF010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4138
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.121"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            555..3194
                     /locus_tag="ACHA1B_002791"
     CDS             555..3194
                     /locus_tag="ACHA1B_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HFM8703498.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3362..4060)
                     /locus_tag="ACHA1B_002792"
     CDS             complement(3362..4060)
                     /locus_tag="ACHA1B_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HFM8703499.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
BASE COUNT         1249 a          793 c          907 g         1189 t
ORIGIN      
        1 aagccgagct ctcgataagc tcggctttct tgtacctcgg aaggattcaa ataaacagaa
       61 atgattgtaa ctttccatca tacatgcaaa gcacggtgtt gaatttcttc atgttaaaca
      121 aaaattttgt tttcgttaca tcttcaacat ttgaaacatc tcttgttcct attcaatttt
      181 cagacgttta cgttattcaa ttgttacgta tcgcattact tcttgtttcg gatacttcgt
      241 gatccaaaca tccatacgca ttcactattt ataggtttgt actctacacg catgtctggg
      301 tgaaacctgt acttctaaca actttgtttg cttacactgt tctatcgaga aattcttctg
      361 tctatttgat ggtatcctcc ttccttacat ctatataata gcatcctttg gtagcgtttg
      421 caaatataag cactttaaat tttacgcttt cttaacaaat aatcgataag ccctttattt
      481 gaagtaaata aaaaaaggat gttatagtaa aataagtacc tttttttgta cgaagatttt
      541 aaaggaggaa taggatggaa gaatacaagc agacaataga agaagtaaag aaggtaacag
      601 aagcagatcc agatactggg ttgtcttcac aagaagtgga tgaacggcga aaaaagcagg
      661 gattgaataa attcgatgag gcgccgaaag aatcgatgat caaaaaattc tttcgaagct
      721 tgtccgattt tacaacgatc atccttcttg tagcagcggt gatttccttt tataccgcat
      781 ttgctacaga acatggggat ttatttgaag gactgctgat catcgctatc gttgtgatca
      841 actcggtatt ggcgattgtc caagaaggaa acgcagaaaa agcactggaa tccttgcaag
      901 atatgaataa acaaacggca actgtcatac gagacggcaa agtgaccact gttgagtcag
      961 agcaactggt agtgggtgat attcttgttt tagagtccgg tgatgctatt tctgccgatg
     1021 cccgtttgat cgaagcatca caattacgtg tagaagaatc ggcgttgact ggagaaagtg
     1081 aagcagttga aaaagatgca gcatttattg ctgaagaaga tgagtcatta ggtgaccaac
     1141 ttaatatggt atttaaagga tgtacggttg ctgcaggtcg tgggaaagcg atcgtcactg
     1201 ccattggcat ggctacagaa atgggtaaga tcgcggatct tttgaacgaa aatactatgc
     1261 aaaaaacacc tttacaggtc cgattgaatc agctaggcaa acgaatcagt atgatcgctt
     1321 tagcggctgc ggctttagta tttgtgattg gtgaactgca aggagaacca ctccttgaga
     1381 tgttcatgac ttcgatttcc ttggctgttg cagctgtacc ggaaaccttg actgttattg
     1441 ttacgttgac acttgcatac ggtgtgcaga agatggcgag gaaacatgcg atcatccgac
     1501 agttgccagc agttgaaacg ctaggaaccg ctaatgttat ctgctcagac aaaacaggaa
     1561 cgctgacaca aaatgaaatg cgcgtccgcc gggtatggag caaagaagat gaagtaacga
     1621 atatcgaaga ttcaatgacg aacagcgcga tggaaatatt gaaaatggct gcactatgta
     1681 cagatgtgac ggtcgagcaa gaagatgacg accttgttat caaaggtaat ccaacagaag
     1741 tagccatcgt aagggctgtt gaagagaatt atcatacaaa ggcagaatta gaagaaaaat
     1801 atccacgagt aaacgagctt ccttttgatt ctgaacgaaa aatgatgaca acagttcacc
     1861 aaatgggcga aaaatacatc tcaatcacca aaggagcatt cgatgttctt gctccgcgct
     1921 ttagttcagg cgatgtagaa caagcggcga tcgttaatga tcgctttggt aaacgggcac
     1981 tgagagtgat tgctgttggt tatgctactt atgacgaaga accgcaagat atttcttctg
     2041 aagcactgga aaaagactta cgtttgattg gtctgatcgg aatgatcgat ccaccacgtc
     2101 cagaaagtaa aggagcaatc aagcgagcga aaaaggctgg catcaaaaca gtcatgatca
     2161 ctggagatca tgtggtgact gccagtgcca tagcgaaaga attaggtatc ttgaatgatc
     2221 cgtcagaagc actttcagga tcagaactgc atcaattatc agacgaagaa ttagatgcgc
     2281 gtgtcaaagc tctctctgtc tatgctcggg taacgccaga agacaagatc cggatcgtca
     2341 aatcttggca acgtacgggt gcagtcgtag cgatgactgg ggatggtgtg aatgatgcac
     2401 cagcgttgaa agcaagtaac gttgggtgtg ccatggggat cacaggaaca gatgtggcgc
     2461 aaagtgccgc agatatgatt ttgacggatg acaactttgc gacgatcgta gacgctgtca
     2521 gtcaaggacg ttcggtttat cagaatattc gtaaagctat caactttttg ctaagctgta
     2581 atatttcgga gatctttatt gttttgattg cgatgctgtt aggatgggga gcaccattta
     2641 cagctgtgca actactgttt gtcaatgtag ttgctgatgg acttccagga tttgctttag
     2701 gaagagagcc agcggaacac ggcatcatgg atcagccacc cattccgaaa aatgaaggga
     2761 tctttgctcg aggtttattg caaaaaattg ccataaatgc aggggtcttc accatcgtaa
     2821 ccttgtttgg ttattattta ggtagttatg tcgatactat cagcccatgg gtagacgcaa
     2881 gtcagcatgt cggtcaaact gttgcattct tgatcttagc ttattcatcg attctgcatg
     2941 tgttcaatgt acgcagcagc caatcgatct tcaaagtcaa tttagcgacc aataaagctt
     3001 tggtagaaat ggcgttactg gcattagcta ttacaacggc tgttgctttg ctgccattta
     3061 cgcaagaact attcggccta gtacacatca gtttgaatca ctggttcttg gtagggattt
     3121 tatctatcgt accaatcgcg gtgaatgaac tgatcaagtt ccatcgatta ccggaagcag
     3181 aagaagagga atgattaact gtttctaagt tgattttctt tttactggaa ctatacaaaa
     3241 aggaggtgtg acatgaatgt tgtcacacct cctttttgct aatgggctga atgtttcttt
     3301 tactgcctct cgataaacgg tgttctcctg ccaccccctc ggtcacaagt cacactctct
     3361 tttaaatatc ttttggcaat tgttcataaa atgctgcttt tgttgcagaa atgtatgggc
     3421 tgagccatag ataaccaata ccagcagttg ctaatgctaa gatatgccag ccgataaatg
     3481 aaagatctaa ccagaaaagt tgtcctttat aaccatccat caattttcga cttgcagtga
     3541 tcgtatccag tactttaggt gtttgtcctg tttcttggac gatatcgtag taaataaaat
     3601 agctttgaga ataagaatag cttttaatga ttccaggaat aactaatagc aaaccccata
     3661 atgttgtaaa gatcgagatc agcacagcta agctgatcac tccgccgata aacaaacctt
     3721 tgaatccacg aaatgcatct ttgaatggtt cgatctgatc tttttgtcca cgtaaaatat
     3781 caagataagt ccaagaaata ccgctcatga acaaagcgct aatgatgctg gaaataattc
     3841 cgccaccgcc tcctgaacta ccgcctcctg aagttgtcgc ttctgagacg ctcgctgatc
     3901 catcatatat ggtggtggca aacaagataa taggaatcat aataagaaga atagtagcaa
     3961 taccaatcaa tgtagggatt agatttagta aaacagcttg tccccaacgt ccttttagac
     4021 tctcttttgc ttggcgtttt aattctgcag aagattgcat gatttttccc tccttttctt
     4081 taataacacc aatataccat gtatcaaaaa atatttctgt cataatgttt ttcttttt
//
LOCUS       DAYYEF010000116         4116 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000116 DAYYEF010000000
VERSION     DAYYEF010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.122"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            155..316
                     /locus_tag="ACHA1B_002793"
     CDS             155..316
                     /locus_tag="ACHA1B_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HFM8703500.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            335..1612
                     /locus_tag="ACHA1B_002794"
     CDS             335..1612
                     /locus_tag="ACHA1B_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8703501.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1622..2278
                     /locus_tag="ACHA1B_002795"
     CDS             1622..2278
                     /locus_tag="ACHA1B_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8703502.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2278..3654
                     /locus_tag="ACHA1B_002796"
     CDS             2278..3654
                     /locus_tag="ACHA1B_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8703503.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3784..>4116
                     /locus_tag="ACHA1B_002797"
     CDS             3784..>4116
                     /locus_tag="ACHA1B_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFM8703504.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1629 a          455 c          727 g         1305 t
ORIGIN      
        1 ctgcgcaagg cttaccagcg agatagagat cgacgatttg ttgtttgaat tcttttgaat
       61 aggttcttcg ttgacgtctt ggcatgaaaa atcctccagt gtgtttttta ttattctaca
      121 caccttattt tttctgtcta gtctagtgta gccgattcag gataaggata agtgtattaa
      181 ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat tcagttgaga attgcaatca
      241 tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt ccagtggatg caattagtta
      301 tggagtaaga aaatagaaag gagtagttag gaaagtgata aaaaatgcta tagcatatat
      361 tacaagaaag aaaaatagaa ctttaataat ttttatcata ttaactatag ttctttcttg
      421 cttgtattct tgtttaacaa taatgaaatc aagcaatgaa atagaaaagg ctttatatga
      481 aagttctaat tcttcaatat caataacaaa aaaagatggt aaatatttta atgttaatca
      541 atttaaagat attgaaaaat taaaagaaat tgaagaaaaa ataattcaat atgatggatt
      601 agcaaaacta aaagatgcta aagtagttag cggagaacaa agaataaata gagaagattt
      661 atctgacgaa tttaagaatg ttgtttcact cgaagctaca aataatacta aaagaaatat
      721 tttatttagt agtggagtat ttacaattaa agaaggtaaa aatatagaag aaaatgataa
      781 gaattcaatt attgttcatg aagaatttgc taaacaaaac aatctaaaat taggtgatga
      841 agttgatctt gaattactag atattgaaaa aagtggaaaa ataaaaagtc ataaatttaa
      901 aattataggg atcttttctg gtaaaaaaca ggaaacatat acaggattat cttctgattt
      961 tagtgaaaat atggtgtttg tagattattc aacaagccaa gagatattaa acaattcaga
     1021 aaataatgaa attgcaaata aaattttaat gtattctggt agtgcagaat ctacagactt
     1081 agccttaaac aaattgaaag agcttaaaat tgatgagtca aagtattttg ttgaaaaaga
     1141 ttctaatgcg tttgaagagt ctttagagtc agtgagtgga ataaaatata taataaaagt
     1201 aatgacttat tctattatgt tgggtgggat ggttgttctt tcattaatct tgattctatg
     1261 gttaagggaa agaatttatg aaataggtat attcttatct attggaacat ctaagataca
     1321 aattataatg caatttatat tcgagttaat attcatatcg ataccaagta taatatcttc
     1381 cttattttta ggaaatgtat tactaaaagt aattgtagat ggattcatta actcagagga
     1441 ttcaatgatt tccggtggaa gtttaataaa taatagtagt tttatgtcaa atataacaac
     1501 acttggacaa agttatttaa tattaataag tattattgtt ttatcagttg tatttgcttc
     1561 ttcattaatg ttaatcaaga agcctaaaga aatcttatca aaaataagtt aggagaaaat
     1621 aatggatata ttagaaataa agaatgtagc atatagttat gcaaattcta aagaaaaagt
     1681 tttgtcagga gtaaatcaaa aatttgaact tgggaagttt tatgcgatag taggaaagtc
     1741 aggaacagga aaatctacac ttctttcctt acttgctgga cttgataaac ctcaaacagg
     1801 aaaaatattg tttaagaatg aagatataca aaataaagga tatagtaatc atagaaaaaa
     1861 taatatatct ttagtatttc aaaactataa tttaatagat tatttatcac caattgaaaa
     1921 tattagatta gtaaataaat cagcagatga aagtatcttg tttgaactag gtttagataa
     1981 aaaacaaata aaaagaaatg ttatgaaatt atctggtgga cagcaacaaa gagtagctat
     2041 tgctagagca ttggtatcag atgctccaat aatactagct gatgagccta ctggtaatct
     2101 agacagtgtt actgctggag aaataattaa tatattaaag acattagcta aagatagaaa
     2161 taaatgtgta atagttgtaa cacatagtaa ggaagtagca gattctgcgg atatcatttt
     2221 agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg aatttggagg ttgaataatg
     2281 ataaaaaatg catttgctta tgtaactaga aaaagtttaa aatcattaat tatcatatta
     2341 gttattttat ctatgtcaac tttaagtctc attagtttat ctattaaaga tgctacggac
     2401 agagcttcaa aagaaacatt tgctaatata acaaatagtt tttctatgga gataaataga
     2461 caagtaaatc caggaacacc tagaggtggg ggaaatgtaa aaggtgaaga tattaaaaag
     2521 atatctcaaa cagatagtat agactcctat gtaaaaagaa taaacagtgt tgcagattta
     2581 gttgattatg atattattga aactcaagag actcttgcga atcaatcacc tgaaagagca
     2641 aagaatttta aaagaacagt tatgttaact ggggttaacg actcaacaaa agaaacaaaa
     2701 tttgtatcag aagcatataa attagtagaa ggaaagcatt tagaaaatga agataaaaat
     2761 aaaatcttaa tgcataaaga tttagctgaa aaaaataacc ttaaagttgg agataagata
     2821 aaaataaaat ctaatttatt tgatgctgat aatgagaaag gtgcagatga aacagtagaa
     2881 gtagaaatta aaggtctatt cgatgggcat aatagcggtg gagtaagtgc agcacaagaa
     2941 ctatacgaaa atacattaat cactgatatt catacagctg ctaaagttta tggtaatacc
     3001 gaagatacag ctgtatacca agatgcaaca ttctttgtaa aaggtgataa gaatcttgat
     3061 agtgtaataa aagatcttgg gaaattagat ataaattgga gagaatataa tttgattaaa
     3121 agttcatcaa attaccctgc attacaacaa tctatatcag gtatttactc aatttcaaat
     3181 aaattatttt ttggctcatt aatatttgca ggagttgtag tttcattatt attattctta
     3241 tggatgaatg ctagaaagaa agaaatagca gtattactat cattaggtat atcaaaatta
     3301 gaaatttttg gtcaattcct aattgagatg gtatttatat caatccccgc attcgttggt
     3361 tcctatttct tagctcaata tacagctgac aagcttggga ataatatatt gaataaggtt
     3421 actggtgata tagctaaaca aatagctaaa caatctgcat ctagccaatt aggtggtggg
     3481 gcagaagctg aaggatttaa caagacatta tcaagtttag atatcaatgt attacctaaa
     3541 ttcatgattt atgtagttat atttatgagt ttagtacttc ttgtatcatt gattatttct
     3601 tcattcaata tattaagaag gaatccaaaa gaattattaa ttgacaataa ttaaaatttt
     3661 cggtgctttt tagcaccaaa aatgagagtg taatataaac cgtgtaagta accatcaatc
     3721 ctaggcgggt ggttgcttca cggtttttat ttttctaaaa taagatcaag aggtgattac
     3781 acgatggcta gaaagaaaag aaatcctgat gctgagaagt tagctgaatc cattttgaat
     3841 acttatcaac ccgaatctgt agaggatatg caagatgttt taaaagatgt gtttggtccc
     3901 ttatttgaaa aaatgcttca aggagaattg aataaccatt tagggtatga cgcccattct
     3961 aaagagccaa agaaacatga caatcgacga aacggttatg gcaataagac gcttaaaacg
     4021 agctttggta aagtaaacat tgatgttccc agagaccggg aggcttcttt tgaacctgag
     4081 ttgattccta atagaaaacg agatgtctcc gacatc
//
LOCUS       DAYYEF010000117         4069 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000117 DAYYEF010000000
VERSION     DAYYEF010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.123"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            85..1434
                     /locus_tag="ACHA1B_002798"
     CDS             85..1434
                     /locus_tag="ACHA1B_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFM8703505.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1562..2152)
                     /locus_tag="ACHA1B_002799"
     CDS             complement(1562..2152)
                     /locus_tag="ACHA1B_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0071805 - potassium ion transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TMEM175 family protein"
                     /protein_id="HFM8703506.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2299..3651
                     /gene="brnQ"
                     /locus_tag="ACHA1B_002800"
     CDS             2299..3651
                     /gene="brnQ"
                     /locus_tag="ACHA1B_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HFM8703507.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1175 a          744 c          789 g         1361 t
ORIGIN      
        1 aaattttgga atcttagttg tgtttttcag aaaactctct taatatggaa gtaattaaac
       61 ttttttagtt aggatgattt aaaaatgaat gaagagcaag aactgcagcg tggactgaaa
      121 aatagacatg tccaactgat ttctattggc ggagcgattg gaacggggtt gtttttaggt
      181 tccggaaagt ctatccagct agctggccct tcgatattgc tcgcctatct tattactgga
      241 tgcatctgtt ttttcattat gcgtgcgtta ggcgaacttc tgttatcaaa caccaataac
      301 cattcttttc tggattttgt tgcagaatat cttggcaaaa aagcggcttt catcactggc
      361 tggacgtatt ggttctgctg ggtatcgatt gcaatggccg atttaacagc catcggaatg
      421 tatgtacgct actgggcgcc tggtgttcct cagtggcttc ctgaactgat tgcattaggt
      481 cttcttcttt gcttgaatat ggtggctgtc tcattgtttg gtgagttaga gttttggttt
      541 gcattgatca aagttgtagc gatcattgcc tttatcctcg taggagctta tatgatcctc
      601 acccactata cgacagatat tggcacagcc agtatcacga atctatggtc tcatggcgga
      661 ttctttccaa ctggtgcaaa aggatttatc ttagctttcc aaatggtaac ctttgctttt
      721 gctgggatag aattagttgg attagtcgct ggagaaacag aaaatcctga aaaagtgttg
      781 ccggaagcta tcaataatat tcctatcagg atcatcttat tttacttagg atctcttttt
      841 gtcattatgg caatctatcc atggaacagc ttgaatccag ataacagtcc atttgtagaa
      901 gtattttcgg aaattgggat cacgattgct gcttccttga tcaatttagt cgtattaagt
      961 gcagcagctt ctgcctgcaa cagtgcaata tatagtacag gacgtatgct tcgttcttta
     1021 gcgcaagaag gcagtgcccc taaaaaattc aaaaagttaa caacacatca tgtgccaggg
     1081 aatgctttga cattttctac tatcgtcatt ttcatttctg ttatcttgaa ttacgtgatg
     1141 cctagtgaag tattcacact agtaagcagt attgccacta cttgtttctt gtttatctgg
     1201 agtatgcttg tctacacgca catgaaatat cgtaaaagta tcctcggcaa aaaagctcat
     1261 tcatttaaaa tgccgttgta cccatttagt aattatctgg tatttcttta catggccttt
     1321 gtgtgtgtcg tcttgttcct aggaaaagat acgagaatcg ctttattact aacacctgtg
     1381 tggttcttgc ttctattact aatctatcat atgaaatatg aacgtaagaa gtaagaaagt
     1441 agttgtgaca gaagtggtca gcttcgagaa ataagaagga atttacgaaa attgcttctt
     1501 aaatttttgt gaaatttcgg cttatttctt ggagataaaa gcttctgtcc cagcctcttt
     1561 tctatttccc cggaaacaac cgctgataat aggcatctgc ttttttatag gaaaaaatcc
     1621 aaataccaga tacaaaaaaa cgtccgaata acccgatcaa cggtacaaaa aagacaccgg
     1681 caatcaagca taagttaatc atcatggaga taagacttcg acggtccttt gacaaaactc
     1741 tcacgacatg ggaatctggt ttatttgctt tcatgatttg cctcatcaag ataccaaaag
     1801 aaaaactcca catcgtgtat actaagacat aagccatctc aggccaaaaa gcttcagggt
     1861 tacgcccgac ccaactagta acagaaggac ataaagtcag ccaaaagagc aaaaagatat
     1921 tcgaccagac cactcggtaa ttaattcgtt ctgccatctg aaatatacga tgatggttca
     1981 cccagatcac cgcaacaaat ataaagctga tggtataagc taataatgta tttcggatga
     2041 cccataaaga atgaaagcta gatgtattag ggatcttgat ctctaataca agaactctca
     2101 aaacaatggc taccactcca tcagtaaatg cttctaatct cgactttgtc acgatgattc
     2161 ctcctcagat gattcagcgc ttttatttta tcacttacgt tattaaataa ccatcgtttt
     2221 atatagggaa ttttctgaaa attgttgcat atttttcgaa attttgttac ttttaaaaaa
     2281 accgtaaagg agttatgtat gacaaaaaaa ttatcattta aagactatct ttttataggc
     2341 tccatgcttt tcggtctatt ttttggtgct ggaaatctta tctttcccgt tcatttgggt
     2401 caagaagcag gcgctgctac cttttgggcg aatctaggtt tcttggttac cggtatcggt
     2461 cttcccttct taggggtgat tgccattggt gtatcgaaaa gctcaggtgt atatgaatta
     2521 gcaaaacgga taaatcaaac atatgcgatg gtttttacca tcttgcttta cttagttatc
     2581 ggaccgtttt ttgctttacc tcgccttgca accacatctt tcgagattgg tttagcacca
     2641 tttatcgatc ctagcagaca gacgctatat ctagcaattt tcagtattgt attttttgtg
     2701 ctggcttggt ggttttcaag aaaaccgaca aagatattag attatgttgg aaagttcctg
     2761 aatcctgcat ttttggtttt attaggtgct ttgcttctcc ttgctttttt gaatccacta
     2821 ggttctgtaa atcaagcgcc tattcagcca aattatcaag agcatgcttt tttcacaggg
     2881 tttactcaag gatataacac attagatgcg cttgctgctt tagcatttgg gatcatcatt
     2941 gtcacaacaa tccaaaacat gggtgtaaca aaacctgctg aaatcgctaa agacacgatc
     3001 aaatctggtg cgatcagcat tatattgatg ggaatcattt atactttgct cgcttattta
     3061 ggtgctatga gcttaggtag ctttgctcta agtgaaaatg gcgggatcac gctggctcag
     3121 attgctgatc attatttagg tacttatggc agtatcttat tagcatttat cgttatatta
     3181 gcttgcttga agaccggtat tggtttgatt acagcttttg cagaaacatt cacagatttg
     3241 tttccgcaaa gaaattacgc attctttgtt gcacttgcta gtatccttcc ttgtttagcg
     3301 gcaaacgtag gcttgacgaa tatcattcaa ttttcgttgc ctgttttgat gttcatctat
     3361 ccattagcaa tgacactgat tttactagtg ttagttggtc ctttgtttaa gcagcgtacg
     3421 gctgtttatc gaatgactac ttattttaca ttgattgctt cgatttttga tgggttgaac
     3481 gcttgcccag aaactatcaa acaaacacct attgttcaaa atcttttata tgttgcggaa
     3541 agctacttgc cgtttttcaa attggggatg gggtggatcg taccagcagt tatcggtttt
     3601 gttatcggac tgatttggag tttcgctaag aaagaagaag tagcagattg ataaaagagg
     3661 ttgtgaaaga gacgttcagc cttgagcaat aaaaagtaat tttgaaaaat ggcttctcac
     3721 atttttgcat aaatttgact taataccgag aaactgactt ttgaacaccg tttattgaga
     3781 ggtcgtgaaa aagccgctta gtttcaagta ttaagaaata ttttgtgaaa atggcttctc
     3841 acatttttgc ataaatttga cttaataccg agaaactggc ttttgaacac cgtttattga
     3901 gcgtctataa actgacctga gtattagaga aacaaaacgg caaagtagct ccatatactt
     3961 tgccgttttg ttttgaacta ataccgaaga gaagctgatc aaacaacatt tcttttataa
     4021 tatagatttt agacatatat atgatataaa aatagttttc gcaaaaaaa
//
LOCUS       DAYYEF010000118         3945 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000118 DAYYEF010000000
VERSION     DAYYEF010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3945
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.124"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..418
                     /locus_tag="ACHA1B_002801"
     CDS             <1..418
                     /locus_tag="ACHA1B_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703508.1"
                     /translation="QEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLD
                     LSEDNPYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMN
                     YAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            632..1327
                     /gene="vanR-A"
                     /locus_tag="ACHA1B_002802"
     CDS             632..1327
                     /gene="vanR-A"
                     /locus_tag="ACHA1B_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFM8703509.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            1305..2459
                     /locus_tag="ACHA1B_002803"
     CDS             1305..2459
                     /locus_tag="ACHA1B_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS-A"
                     /protein_id="HFM8703510.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            complement(2557..3849)
                     /locus_tag="ACHA1B_002804"
     CDS             complement(2557..3849)
                     /locus_tag="ACHA1B_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1251 family transposase"
                     /protein_id="HFM8703511.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT         1281 a          704 c          824 g         1136 t
ORIGIN      
        1 acaggaagat gacatcattt atgttacaga cttaactcga atcactcgta gtacacaaga
       61 tctatttgaa ttaatcgata acatacgaga taaaaaggca agtttaaaat cactaaaaga
      121 tacatggctt gatttatcag aagataatcc atacagccaa ttcttaatta ctgtaatggc
      181 tggtgttaac caattagagc gagatcttat tcggatgaga caacgtgaag ggattgaatt
      241 ggctaagaaa gaaggaaagt ttaaaggtcg attaaagaag tatcataaaa atcacgcagg
      301 aatgaattat gcggtaaagc tatataaaga aggaaatatg actgtaaatc aaatttgtga
      361 aattactaat gtatctaggg cttcattata caggaaatta tcagaagtga ataattagcc
      421 attctgtatt ccgctaatgg gcaatatttt taaagaagaa aaggaaacta taaaatatta
      481 acagcctcct agcgatgccg aaaagccctt tgataaaaaa agaatcatca tcttaagaaa
      541 ttcttagtca tttattatgt aaatgcttat aaattcggcc ctataatctg ataaattatt
      601 aagggcaaac ttatgtgaaa gggtgataac tatgagcgat aaaatactta ttgtggatga
      661 tgaacatgaa attgccgatt tggttgaatt atacttaaaa aacgagaatt atacggtttt
      721 caaatactat accgccaaag aagcattgga atgtatagac aagtctgaga ttgaccttgc
      781 catattggac atcatgcttc ccggcacaag cggccttact atctgtcaaa aaataaggga
      841 caagcacacc tatccgatta tcatgctgac cgggaaagat acagaggtag ataaaattac
      901 agggttaaca atcggcgcgg atgattatat aacgaagccc tttcgcccac tggagttaat
      961 tgctcgggta aaggcccagt tgcgccgata caaaaaattc agtggagtaa aggagcagaa
     1021 cgaaaatgtt atcgtccact ccggccttgt cattaatgtt aacacccatg agtgttatct
     1081 gaacgagaag cagttatccc ttactcccac cgagttttca atactgcgaa tcctctgtga
     1141 aaacaagggg aatgtggtta gctccgagct gctatttcat gagatatggg gcgacgaata
     1201 tttcagcaag agcaacaaca ccatcaccgt gcatatccgg catttgcgcg aaaaaatgaa
     1261 cgacaccatt gataatccga aatatataaa aacggtatgg ggggttggtt ataaaattga
     1321 aaaataaaaa aaacgactat tccaaactag aacgaaaact ttacatgtat atcgttgcaa
     1381 ttgttgtggt agcaattgta ttcgtgttgt atattcgttc aatgatccga gggaaacttg
     1441 gggattggat cttaagtatt ttggaaaaca aatatgactt aaatcacctg gacgcgatga
     1501 aattatatca atattccata cggaacaata tagatatctt tatttatgtg gcgattgtca
     1561 ttagtattct tattctatgt cgcgtcatgc tttcaaaatt cgcaaaatac tttgacgaga
     1621 taaataccgg cattgatgta cttattcaga acgaagataa acaaattgag ctttctgcgg
     1681 aaatggatgt tatggaacaa aagctcaaca cattaaaacg gactctggaa aagcgagagc
     1741 aggatgcaaa gctggccgaa caaagaaaaa atgacgttgt tatgtacttg gcgcacgata
     1801 ttaaaacgcc ccttacatcc attatcggtt atttgagcct gcttgacgag gctccagaca
     1861 tgccggtaga tcaaaaggca aagtatgtgc atatcacgtt ggacaaagcg tatcgactcg
     1921 aacagctaat cgacgagttt tttgagatta cacggtataa cctacaaacg ataacgctaa
     1981 caaaaacgca catagaccta tactatatgc tggtgcagat gaccgatgaa ttttatcctc
     2041 agctttccgc acatggaaaa caggcggtta ttcacgcccc cgaggatctg accgtgtccg
     2101 gcgaccctga taaactcgcg agagtcttta acaacatttt gaaaaacgcc gctgcataca
     2161 gtgaggataa cagcatcatt gacattaccg cgggcctctc cggggatgtg gtgtcaatcg
     2221 aattcaagaa cactggaagc atcccaaaag ataagctagc tgccatattt gaaaagttct
     2281 ataggctgga caatgctcgt tcttccgata cgggtggcgc gggacttgga ttggcgattg
     2341 caaaagaaat tattgttcag catggagggc agatttacgc ggaaagcaat gataactata
     2401 cgacgtttag ggtagagctt ccagcgatgc cagacttggt tgataaaagg aggtcctaag
     2461 agatgtatat aattttggct ctttgtcaaa tgatgttggt aaagagaaat cttagaataa
     2521 ttggagatca agtggatcag ttcctcttga tcttttttag ttgaaaatca atgcgttgcc
     2581 atgacgaatc atgatgcgca atttgaaatt ataaaagcta cgaaagccat atgcatttcg
     2641 ttttaacact ttgatatggt tgttcagaca ttcaagtggg ccatttgaat aactttgttg
     2701 taaagcattt ttgatttgtg gcagaaattt ctggaacgtt ctcaaggtcg tctgatagcc
     2761 ttcgggaagc atgatattat tggtaagtag ttcttcaaac gatacgtagt ctcgttcctt
     2821 tacagcgtaa agaaagtctt gatataactg atagcctaca cgcaaagcag ggctcccttt
     2881 cagtaagcga tccacaatat cggtctctgt taaatgagct ttgaagccag gtcgccaaag
     2941 gcgtcgagta taatcaagct tgcgttcatc tttttgaaga agtttccagt atctttttaa
     3001 ttgcttacct aattgatagt gtttttgttc tttgcttttt aatagttggt tcgtttcttt
     3061 gattcgatga ttgcgaaagg tacgaccaat atgttggacg atgtgaaacc ggtcaataat
     3121 cagctgtgct tttggaaaca gctttttaac gagcgataca taaggagcgt acatatcaat
     3181 cacgatccat tcgaccgctt cacgaatttc tcgtgaaaaa tgactaaaat aacgttttaa
     3241 aaaaggcagt tgtcggttct cgacaatgtc caataagcgc tgtgtttgtc catccatcat
     3301 gatgaaactc atagcacctg aaacaccccg aactgatttg aattcatcaa aacaaagtac
     3361 cttaggtaac ggtgtccgaa aaggattcaa cggacgataa aatcgcttca taatacggta
     3421 aacagaagag accgatagat ttttctgagc ggcgatctct gtcattgagg tatttttttt
     3481 cagacgagtc acgacagacc agcggacttt ctcactgatg aaacaatgtt ttttcgcaac
     3541 agaagtatct gcgacaaagg tccgctgaca agctttgcat ttgaagcgtt gctttttcaa
     3601 ttcgaggtag gtacggtatt cagaaacatc gttcattaac aaccggacgg ttgttgtacc
     3661 ccaacgcaca atatctgaag caatctggtg tttacagtgg atgcattctt gggctgtata
     3721 aatcaagttt ccacgataaa tatgacagat ttgccctttg tatttttctt ttgtgagaca
     3781 attttcgtta aaagtaactg ataagtctag aatatctaat gtttctttga taaggtgagt
     3841 gtaagacatc ttgattcctc cttttgggtt ggttcgccaa attaattcta aaggatttca
     3901 aggtgtcttt tctatatgtt ttggaaaata aaaaagatgc tggtg
//
LOCUS       DAYYEF010000119         3856 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000119 DAYYEF010000000
VERSION     DAYYEF010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.125"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(50..301)
                     /locus_tag="ACHA1B_002805"
     CDS             complement(50..301)
                     /locus_tag="ACHA1B_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family DNA-binding protein"
                     /protein_id="HFM8703512.1"
                     /translation="MEQLALVNLSALKASLTESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWANSTEH"
     gene            complement(315..506)
                     /locus_tag="ACHA1B_002806"
     CDS             complement(315..506)
                     /locus_tag="ACHA1B_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703513.1"
                     /translation="MSNLDNGRAAIKKFMRENGVTMEDLATAYGYTRVRMQQIIDGHW
                     SGPKANKTILEIIRDYRIR"
     gene            799..1119
                     /locus_tag="ACHA1B_002807"
     CDS             799..1119
                     /locus_tag="ACHA1B_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8703514.1"
                     /translation="MTLFERIKSLASQRDKSMKEVALELGFSENLFYRWKTTEPKARD
                     LQKVADYFNVSVDYLLGREEKETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            1137..1559
                     /locus_tag="ACHA1B_002808"
     CDS             1137..1559
                     /locus_tag="ACHA1B_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HFM8703515.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFEAEADRIAIMILLNIFIENELTDE
                     SQFKLENFMEFYSINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            1642..2277
                     /locus_tag="ACHA1B_002809"
     CDS             1642..2277
                     /locus_tag="ACHA1B_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HFM8703516.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAQNNVLQAQTGYFGTETVSIALHN"
     gene            2395..3606
                     /locus_tag="ACHA1B_002810"
     CDS             2395..3606
                     /locus_tag="ACHA1B_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8703517.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKANSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLRHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFEKLLKKDIK"
BASE COUNT         1417 a          617 c          682 g         1140 t
ORIGIN      
        1 ctatttcccc aaagccctaa agcgtagatg attagcggtg cgctgaatac tagtgctctg
       61 ttgaatttgc ccatgttttt cctcctttta gatactgata caaagcgata ctactaaacc
      121 tccactctct gccaactttc gctgctggaa tctttccaga ttcggcatct ttagttagcg
      181 tgcgtgtcgt ggttttcaaa tattccgcag cttgctttgt atcccacact tcatttgcaa
      241 tctcagattc tgtcaaagaa gctttgaggg ctgagaggtt aactaaagct agttgttcca
      301 ttgattaatt cctcctatcg aattctgtaa tcacggatga tttctaagat agttttatta
      361 gcttttggtc cactccaatg gccatcaata atttgctgca ttcgaacacg tgtgtatcca
      421 tatgcagtag ccaaatcttc catagttact ccgttttctc gcataaactt cttgattgca
      481 gcacggccgt tatctagatt tgacatctat tcactcccct tacatataga tttgtaagtc
      541 aaaatgatag aaaaaacgta taaactattg actaatagta tacaatcgta tactatataa
      601 acatagttaa ataagcctac aacaaaccct ttattatgca atcggtcgcc aaacttaatg
      661 ctataaggtg tatttttagt ttgctttttt tctatcaaat taacttacaa acaaataata
      721 atacaaactt atacttatgt caacagtata atttacattt tgtgtacttt tatttgttta
      781 ggattggaga acattattat gacactgttt gaaaggataa aatcattagc tagccaaaga
      841 gataaaagca tgaaagaagt cgctttagaa ttaggattta gcgaaaatct tttctatcga
      901 tggaaaacaa cagaacccaa agcaagagat ttgcaaaagg tagctgacta tttcaatgtc
      961 tctgtagact atcttctagg tagagaagaa aaagaaacgc ctaaacatgt ggatttatca
     1021 gaagatgata ctgtattttc ttttgatgga aaagaaatat ctaaggagac aatgcgtaaa
     1081 gcgattgcaa ttgctaaagc tttagaggaa aatgaatagt tggagtgatg ggttgtatgt
     1141 atttaaagtt gaaagaaatg ctgagtgagt ataatttaaa gttaatctat atggaaatgg
     1201 aagaaccagg tttttattat ccaaaaccaa gaatagtatt tttgaatgaa aaactacacg
     1261 aagacagttc tgaagctttt catttagccc atgagctcgg tcatttcatt gcttcacatt
     1321 ttgaatattc agtactgtac gataactcta caacttttca ttcaaaattc gaagctgaag
     1381 ctgatagaat cgcaattatg attttactaa atatctttat tgagaacgaa ttgactgatg
     1441 aatctcagtt caaattagaa aatttcatgg aattctactc tatcaataat aagttaagaa
     1501 cagaatgttt taatgtttgc cagtcatatt tcaagaaaaa atactcttat gcacagtaaa
     1561 aaaagcccgt gctgcaacac ggactcatac ctcatttctg agatcacaaa tatattataa
     1621 caagaagtga gggatattta aatggcaaaa aaagttatgg gtcaagatgg gaaaatgtat
     1681 aaggttaaaa aaccgtttta taaacgggta tggttttggg tattaatagt acttttgttt
     1741 tttggtattg gtggtgctct aagtggcggt gaaaacaaag attcagctac tgcaacatca
     1801 acaagtacta ataaagaaac tacaaaagaa actacaacaa aagaagaaaa gacttataaa
     1861 atcggtgatg acgttgctgt agggaaaatg gaatacaaag taaactccgt tgaagtagta
     1921 aaacaagttg gcccatctgt acttcctact aacgcaaaag acactttctt agtagttgac
     1981 ttatctgtaa aaaatgcagg tgataaggct gtgactgttg atagctcatt cttcaaatta
     2041 aaagcagatg gaaaaacttt cgaagctgat tcggctgcat ctatgtcggc aaatcaagat
     2101 gaaaatggta atatcactaa ctctttcttt atggaaagct taaatcctga tatgcaacaa
     2161 actggtaaaa tagtttttga tatctctgaa gcccaagcaa atgcacaaaa taatgtattg
     2221 caagcacaaa caggttactt tggaacagag acagtttcaa ttgctcttca taactaatta
     2281 gtataaaaaa cacgccccac cgaccaaagc gagcgtgttc taagaaaaaa caaacctaca
     2341 caataggctt ctttatagta cctattgtat cagagaaaga gagctgattc aattatgtca
     2401 gaagtaacag gatacttaga acaagtagac aatgaaacat atagactaag agctgtatta
     2461 gggtacaaac ctgatggctc ggcaaaaaga aaaagcaaaa ctataaaagc gaatagtaaa
     2521 agagcggcat ataaagaatt gaacatctgg ttagagcaat tcgaaggaat gaccgatgat
     2581 tcgttggatt tattcaatat aacttttggt gaattttata gaaaaatatg gctttcagag
     2641 gccgaaaaaa atttagagcc aaagtcttat cataactata agcgaatgat cgagaataga
     2701 tttcttgata aatttgattt tatccctcta atcgatataa aaccatacat gataaagaaa
     2761 attgttgtta atgctcaaag aatcaataca aaagatcctg gaagaaactc tgataaacct
     2821 ttatcaagaa atacaaagct tcgtatgtta tacgccgtta acaacttatt tttgatggct
     2881 aaaaatgagt acggagcaat taaagaaaat cctgtggaaa atgtaaaaat accaaaagaa
     2941 aaaggcgtaa aaaagaatat cgaagaacct tattcggaag aagaaattca tgcaatgcta
     3001 aaagcagcat ttgaggaaag catagaaatt aaaactttaa ttgttctagc atttattaca
     3061 ggagcaagac aaggagaaat tgcagcttta gaagaaaaag atattgactt tgacaaacaa
     3121 gaaataagat ttcatcagcg gatttcagaa gtggatggaa aatcagatat tcggttgctg
     3181 ccaggtttga aaaatgatga tgatgaaaaa atagtaaccg gtcctgctta tctatttgat
     3241 atgttagatg aattgatcaa agagaataaa aaaattcgtt ggaaattaaa tataaagaaa
     3301 ttaagacact attttatatt tgatacaaaa caagacggaa ctttaccacg tggaagttat
     3361 ctgtataaga agttcaaacg attcaccaaa cgtcacaatt tgcgtcacat tcgttttcac
     3421 gacattagac atacatcagc tacctatttg cttagcgatc ctaatatgac tccaaaagag
     3481 cttcaaaaac gattaggaca ccgagatttt aatactacaa tgaatgttta tggccatgtc
     3541 ttacgcaaag aaaaagatac agcaactaca gcgtttgaaa aactattaaa aaaagatata
     3601 aaataacact aaaaaattat attttcgggt ataaactcgg gtaggatata taaaaacttg
     3661 ggataatttg cggtatataa gcatttaaaa atgctgtaaa ttcgcttatc ttcatttaaa
     3721 ataccattaa ataacgaact cttaatcagc gggtcgcggg ttcgagcccc tcacggccca
     3781 ttgggtgcca aacccacgga acaggtaaat gttggtgcga aagcatttcg aaaacattta
     3841 cgctgttctt ttttta
//
LOCUS       DAYYEF010000120         3598 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000120 DAYYEF010000000
VERSION     DAYYEF010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.126"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(184..1095)
                     /locus_tag="ACHA1B_002811"
     CDS             complement(184..1095)
                     /locus_tag="ACHA1B_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFM8703518.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(1114..1458)
                     /locus_tag="ACHA1B_002812"
     CDS             complement(1114..1458)
                     /locus_tag="ACHA1B_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703519.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(1478..1756)
                     /locus_tag="ACHA1B_002813"
     CDS             complement(1478..1756)
                     /locus_tag="ACHA1B_002813"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703520.1"
                     /translation="MSVEHFCDCYIALLRSQQLLTVERYGAEFGYVMQAERHRATRCY
                     EKEDQVIDGYEELCIRNNRYLQQRLYEQLMMDFSNLYRGYECSMIQER"
     gene            complement(2115..2615)
                     /locus_tag="ACHA1B_002814"
     CDS             complement(2115..2615)
                     /locus_tag="ACHA1B_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703521.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(2616..3161)
                     /locus_tag="ACHA1B_002815"
     CDS             complement(2616..3161)
                     /locus_tag="ACHA1B_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703522.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(3158..>3598)
                     /locus_tag="ACHA1B_002816"
     CDS             complement(3158..>3598)
                     /locus_tag="ACHA1B_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFM8703523.1"
                     /translation="LEALTKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVG
                     LINAKLIVWDRLESDARIVDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPT
                     LKLLQEADRILGRDFVQEGIDNAELNDEQQNYLEWMGTSGGKIA"
BASE COUNT         1007 a          783 c          522 g         1286 t
ORIGIN      
        1 caaacaccaa atccatttca ctgctttttt tgaatggatt ttcttttgct tcggtacttt
       61 ctctgtataa actttttctt tccgccgtag ttgtcgtttt ttcataagct actccttcta
      121 gtatgttttt actagtacgt acgattgaca acgataagct tgtttttctg aaaaatagtc
      181 cattcaatta ccctcatttt ctattccttt tctctttctt ttatatccaa caaatccagc
      241 aatacttgtc aacactcctc ctagaacaga aagtgcaaca tgtatttctt caccagtctt
      301 tggtaagact tttgtttttc catctgctgt tttgatttca atattgccac ttggaagttt
      361 ctttacagga atcgacaaat cctttaccaa attcccttca ctatcttgga ttaatggaat
      421 accatctttt acaccaacaa ttgtttgatc acctgctact tttaatgggg tggttggtgt
      481 tggaatatgg gtcaattcct ctacattact agtgacaatc ggtacactca ttccttgaga
      541 agtattcgtc gtaatttcac cgcttggggt taccgatact gtgacttctt ttgctggaac
      601 aataggttta ttttcttttg gaattgcttc tgatttttca acaggttgtt tcggttcttc
      661 tttttgttct tcactggtag acgacatcgt tggctgttcc gtacttgacg aatcagtatt
      721 cttttcagaa gaactggttg ttcctgattg ttccggagtt gtgactatac ttgaatccgt
      781 tgttgttgaa ctatgcacac cttcttcttc gatcgaatca gtcggtaaag ttgattcagg
      841 aaactctggt tctggtgtca ctggctcttt ttcaggtttc tctgactgca attgttcagg
      901 ttctgctggt ttttccgttg ttcctccatt tagctctgtc tcaacatctg gtaatccttc
      961 ccctggcaat gtttctacaa tttctgactt aggtgtttct acagtttcat ctgcataaac
     1021 caatgaactc cctaattgaa acgaaaataa tgaaattcct agtgttgtta cgactgctaa
     1081 tgttgttttt ttcatgatta ttcctccaat tttttatgca attcgtgttt tgttcataga
     1141 cgccgcacta atattatctg aacgataaaa gaactcccgt ccgttttctt ctaacccaac
     1201 atatggatta tttttgaata attgaatcaa tagttcactg gtgttgtatt ttggatagtt
     1261 tgcaaaaaaa taatactgtg cttgtcgccc atccgaaaat tcaacaagta attcataacg
     1321 ataccgcttc aatccttttc gttgttttaa aggatctcta taccaacttg tccatcgttc
     1381 cattcgtgga tagagataga cacgatacac atagaacaat gccataccac ataccaccaa
     1441 aaataataat cgccacataa aaattccccc ttttcttcta cctttcttga atcatcgaac
     1501 attcataccc tctatagaga tttgaaaaat ccatcatcaa ttgttcatat aaacgttgtt
     1561 gcaaatagcg attgtttcga atacataatt cttcatagcc atcaatcact tgatcttctt
     1621 tttcatagca tcttgtagct ctatgacgct cagcttgcat gacataacca aactctgcac
     1681 catatcgttc tactgttaat aactgttgac tacgcaataa tgcaatataa caatcacaaa
     1741 aatgttcaac cgacatttga tttttctcac gtttgtgaaa taggtattct ttagaaagca
     1801 cattattcgt taaacaatct gataaatagc gataatctgg cggtcggtta ttttcatctg
     1861 tgaatttttc ccataataaa ctgattttta ttcgttcagc ggctagatag tcttgttcgc
     1921 gtggataaaa ttcatcaatc gcacaaagtt ttttatcacc tgaataaaca aatccatata
     1981 atgcgaaacg aactcttcct tttcaattgg ctctcctaaa aattccagtg acataccatc
     2041 ttctccttcc taaaaaaaat aaaaaagcag aaaccgattt ggcttctact tttctttcct
     2101 tttatagctc ttttttacgg aagaatccgc aaatgacatt ttttcaaaaa atcaatcggc
     2161 acaagttcac gaaaacttgg agcaattttg gatagaatca cttccccatc ttgtaaaata
     2221 caatcataaa aatcatcagt tacttgatac ttacgcttct tacaataatt gataaaatag
     2281 tagcgatcat tttctatttc cattcgttgt tctactaagc gcatacgaac atcatcatag
     2341 aaataagcca caaatcgccc ttcaagttca tgtttttcaa tgggatactc ttctggtaac
     2401 aatctatttt ttcgtcgttt atacattgct ggatacctta gaagaagttc atctaaacgt
     2461 ctgtcagtat atggtaactg acgaatcaac gattctaatc gttctttata cagatagaat
     2521 aattggcgca agcaatagtg taccgcctct ggattttcta atactgttgg atcacgtgac
     2581 caatacgcac caacataaat cataattttt ttcatttaga caatcacacc agcaatacta
     2641 atgaccgatc cacaataggt agaacaagtg gcatagcgac caatttcctc taattctatc
     2701 tcaatctctt ctaaagaaag atatgtctgt tcttctgttg gctggcgact catttcccaa
     2761 gtgacagtca ccaatgaaat ttcttccata agaggttttt cgctgctaag tgctgccaca
     2821 cagttttcat atatcttcat tttatcgcag ccttttttaa ccgctaaaat cgcaggtatt
     2881 ggcaatgaaa atcgataaaa gcgaatgaat tctagccttc ctttccttcg gctaaattcc
     2941 aactcttcga gttcttgttc gtatccctta cgaacttcta ataagcgtgc aatttcttgc
     3001 cagttctctt tttcctgata acgtccagct tttaccgctt gttcaatata aggaactcga
     3061 aaacgaaaat aagacaaatc aaccatcttt tcatttaatg cttcgattgc agcctttaaa
     3121 tccaacaggc gcagccattc tgttgtcgta tatgcattca tgcaattttc cctcctgacg
     3181 ttcccatcca ttctagatag ttttgttgct cgtcatttag ttcggcatta tcaatccctt
     3241 cttgtacaaa gtctcttcct aaaatacgat ctgcttcttg taacaacttt aatgtcggag
     3301 ctacttgttt caaaaaccag cgttctgaac gatctaatga gaatttttct ggctttactg
     3361 taaaatccaa ttcttccatc gaacgaaata attttgccca tcgtttatca acaatccgtg
     3421 catcactttc cagtctatcc caaacaataa gttttgcatt aattaaacca acgccaatct
     3481 ctcctaaacg tttcggtgaa tcacctaaaa taaatgcttc tactgcttgt gttgctttct
     3541 cattggctaa ccgtaactca tatcgattat aaataccata tttcgttaat gcttctaa
//
LOCUS       DAYYEF010000121         3598 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000121 DAYYEF010000000
VERSION     DAYYEF010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.127"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..441
                     /locus_tag="ACHA1B_002817"
     CDS             <1..441
                     /locus_tag="ACHA1B_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFM8703524.1"
                     /translation="LGALTKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVG
                     LINAKLIVWDRLESDARIVDERWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPT
                     LKLLQEADRILGRDFVQEGIENAELNDEQQSYLEWMGTSGGKIA"
     gene            438..983
                     /locus_tag="ACHA1B_002818"
     CDS             438..983
                     /locus_tag="ACHA1B_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703525.1"
                     /translation="MNAYMTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLATVTWEMSRQPTEEQTYLSLEEIELELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            984..1484
                     /locus_tag="ACHA1B_002819"
     CDS             984..1484
                     /locus_tag="ACHA1B_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703526.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKRELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            1564..2121
                     /locus_tag="ACHA1B_002820"
     CDS             1564..2121
                     /locus_tag="ACHA1B_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703527.1"
                     /translation="MSLEFLGEPIEKEEFVSHYMDLFIRVIKKLCAIDEFYPREQDYL
                     VAERIKISLLWEKFTDENNRPPDYRYLSDCLTNNVLSKEYLFHKREKNQMSAEHFCDC
                     YIALLRSQQLLTVERYGAEFGYVMQAERHRATRCYEKEDQVIDGYEELCIRNNRYLQQ
                     RLYEKLMMDFSDLYRGYQCSVIQER"
     gene            2141..2485
                     /locus_tag="ACHA1B_002821"
     CDS             2141..2485
                     /locus_tag="ACHA1B_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703528.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRTERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISTASMNKTRIA"
     gene            2504..3415
                     /locus_tag="ACHA1B_002822"
     CDS             2504..3415
                     /locus_tag="ACHA1B_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFM8703529.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVEILP
                     GEGLPDVETELNGGTTEKPAEPEQLQPEKPEKEPVAPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEPKEEPKQPAEKSEAIPK
                     ENKPVVPAKEVTVSVTPNGEITTNTSQGMSVPIVTSNVEELTHIPTSTTPLKAEGGQT
                     IVGVKDGIPLVQDSEGNLVKDLSIPVKKLPSGNIEVKTADGKTKVLPKTGEEIHVALS
                     VLGGLLTSIAGFVGYKRKRKGIENKGN"
BASE COUNT         1279 a          525 c          792 g         1002 t
ORIGIN      
        1 ttaggagcat taacgaaata tggtatttat aatcgatatg agttacggct agctaatgag
       61 aaagcaacac aagcagtaga agcatttatt ttaggtgatt caccgaaacg tttaggagag
      121 attggtgttg gtttaattaa tgcaaaactt attgtttggg atcgactgga aagtgatgca
      181 cggattgttg atgaacgatg ggcaaaatta tttcgttcga tggaagaatt ggattttaca
      241 gtaaagccag aaaaattctc attagatcgt tcagaacgct ggtttttgaa acaagtagct
      301 ccgacattaa agttattaca agaagcagat cgtattttag gaagagactt tgtacaagaa
      361 ggaattgaga atgccgaact aaatgacgag caacaaagct atctagaatg gatgggaacg
      421 tcaggaggga aaattgcatg aatgcatata tgacaacaga atggctgcgt cttttggatt
      481 taaaggctgc aatcgaagca ttaaatgaaa agatggttga tttgtcttat tttcgttttc
      541 gagttcctta tattgaacaa gcggtaaagg ctggacgtta tcaggaaaaa gagaactggc
      601 aagaaattgc acgcttatta gaagttcgta agggatacga acaagaactc gaagagttgg
      661 aatttagccg aaggaaagga aggctagaat tcattcgctt ttatcgattt tcattgccaa
      721 tacctgcgat tttagcggtc aaaaaaggct gcgataaaat gaagatatac gaaaactgtg
      781 tggcagcact tagcagcgaa aaacctctta tggaagaaat ttcattggcg actgtcactt
      841 gggaaatgag tcgccagcca acagaagaac agacatatct ttctttagaa gagattgagc
      901 tggaattaga ggaaattggt cgctatgcca cttgttctac ctattgtgga tcggtaatta
      961 gtattgctgg tgtgattgtc taaatgaaaa aaattatgat ttatgttggt gcgtattggt
     1021 cacgtgatcc aactgtatta gaaaatccag aggcggtaca ctattgtttg cgccaattat
     1081 tctatctgta taaagaacga ttagaatcgt tgattcgtca gttgccatat actgacagac
     1141 gtttagatga actgcttcta aggtatccag caatgtataa aagacgaaaa aatagattgt
     1201 taccagaaga gtaccccatt gaaaaacgtg aacttgaagg gcgatttgtg gcttatttct
     1261 atgatgatgt tcgtatgcgc ttagtagaac aacgaatgga aatagaaaat gatcgctact
     1321 attttatcaa ttattgtaag aagcgtaagt atcaagtaac tgatgatttt tatgattgta
     1381 ttttacaaga tggggaagtg attctatcta aaattgctcc aagttttcgt gaacttgtgc
     1441 cgattgattt tttgaaaaaa tgtcatttgc ggattcttcc gtaaaaaaga gctataaaag
     1501 gaaagaaaag tagaagccaa atcggtttct gcttttttat tttttaagga aggagaagat
     1561 ggtatgtcac tggaattttt aggagagcca attgaaaagg aagagttcgt ttcgcattat
     1621 atggatttgt ttattcgggt gataaaaaag ctttgtgcga ttgatgaatt ttatccacgc
     1681 gaacaagact atctagtcgc tgaacgaata aaaatcagtt tattatggga aaaattcaca
     1741 gatgaaaata accgaccgcc agattatcgc tatttatcag attgtttaac gaataatgtg
     1801 ctttctaaag aatacctatt tcacaaacgt gagaaaaatc aaatgtcggc tgaacatttt
     1861 tgtgattgtt atattgcatt attgcgtagt caacagttat taacggtaga acgatatggt
     1921 gcagagtttg gttatgtcat gcaagctgag cgtcatagag ctacaagatg ctatgagaaa
     1981 gaagatcaag tgattgatgg ctatgaagaa ttatgtattc gaaacaatcg ctatttgcaa
     2041 caacgtttat acgaaaaatt aatgatggat ttttcggatc tctaccgagg ctatcaatgt
     2101 tcggtgattc aagaaaggta gaagaaaagg gggaattttt atgtggcgat tattattttt
     2161 ggtagtatgt ggtatggcat tgttctatgt gtatcgtgtc tatctctatc cacgaacgga
     2221 acgatggaca agttggtata gagatccttt aaaacaacga aaaggattga aacggtatcg
     2281 ttatgaatta cttgttgaat tttcggatgg gcgacaagca cagtattatt tttttgccaa
     2341 ctatccaaaa tacaacacca gtgaactatt gattcaatta ttcaaaaata atccatatgt
     2401 tgggttagaa gaaaacggac gggagttctt ttatcgttca gataatatta gtacggcgtc
     2461 tatgaacaaa acacgaattg cataaaaaat tggaggaata atcatgaaaa aaacaacatt
     2521 agcagtcgta acaacactag gaatttcatt attttcgttt caattaggga gttcattggt
     2581 ttatgcagat gaaactgtag aaacacctaa gtcagaaatt gtagaaatat tgccagggga
     2641 aggattacca gatgttgaga cagagctaaa tggaggaaca acggaaaaac cagcagaacc
     2701 agaacaattg cagccagaga aacctgaaaa agagccagtg gcaccagaac cagagtttcc
     2761 tgaatcaact ttaccgactg attcgatcga agaagaaggt gtgcatagtt caacaacaac
     2821 ggattcaagt atagtcacaa ctccggaaca atcaggaaca accagttctt ctgaaaagaa
     2881 taccgattcg tcaagtacgg aacagccaac gatgtcgtct accagtgaag aaccaaaaga
     2941 agaaccgaaa caacctgctg aaaaatcaga agcaattcca aaagaaaata aacctgttgt
     3001 tccagcaaaa gaagtcacag tatcggtaac cccaaacggt gaaattacga cgaatacttc
     3061 tcaaggaatg agtgtaccga ttgttactag taatgtagag gaattgaccc atattccaac
     3121 atcaacaact ccactaaaag cagaaggtgg acaaacaatt gttggtgtaa aagatggaat
     3181 tccattagtc caagatagtg aagggaattt ggtaaaggat ttgtcgattc ctgtaaagaa
     3241 acttccaagt ggcaatattg aagtcaaaac agcagatgga aaaacaaaag tcttaccaaa
     3301 gactggtgaa gaaatacatg ttgcactttc tgttctagga ggattgttga caagtattgc
     3361 tggatttgtt ggatataaaa gaaagagaaa aggaatagaa aataagggta attgaatgga
     3421 ctatttttca gaaaaacaag cttatcgttg tcaatcgtat gtactagtaa aaatatacta
     3481 gaaggagtag cttatgaaaa aacgacaact acggcggaaa gaaaaagttt atacagagaa
     3541 agtaccgaag caaaagaaaa tccattcaaa aaaagcagtg aaatggattt ggtgtttg
//
LOCUS       DAYYEF010000122         3459 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000122 DAYYEF010000000
VERSION     DAYYEF010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.128"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..807
                     /locus_tag="ACHA1B_002823"
     CDS             <1..807
                     /locus_tag="ACHA1B_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HFM8703530.1"
                     /translation="TYYYQAKPIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGL
                     QLSRRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTTNVLDRTFTQEQPLEAIVTDL
                     TYVRVRKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDR
                     GKEFDSQTIHEILNGFGITRSLSRKGCPYDNAVAESTHKSVKVEFVHQYQFETLAQLR
                     LELFDYVHWWNYLCLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
     gene            913..1128
                     /locus_tag="ACHA1B_002824"
                     /pseudo
     CDS             913..1128
                     /locus_tag="ACHA1B_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1763..2722
                     /locus_tag="ACHA1B_002825"
     CDS             1763..2722
                     /locus_tag="ACHA1B_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFM8703531.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(2709..3314)
                     /locus_tag="ACHA1B_002826"
     CDS             complement(2709..3314)
                     /locus_tag="ACHA1B_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703532.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
BASE COUNT         1159 a          590 c          592 g         1118 t
ORIGIN      
        1 acctactatt atcaagcgaa accgatcgaa aatgagtccg acttagaaga gatcgttcag
       61 gaagagttta ttcgaaaccg aaaggcttac ggtacccgaa aattgaagaa gtgtttagca
      121 aagcgtgggc ttcaactcag tcggcgccga atcggtcgaa tcatgaaacg ccgcggattg
      181 acatctacct atacgatcgc tcattttaaa gggcaacgaa cagcttgtaa tgaagcgaaa
      241 acaacgaatg tattagatcg gacctttaca caagaacagc cattggaagc catcgttacg
      301 gatcttactt atgttcgcgt gaggaaaaag tggcattata tctgcttaat acttgatttg
      361 tttaatcgag aaattattgg ttattcctgt ggtgagaaga aagatgcctc attggtaaaa
      421 gaagcctttg gacggatacc gtattcttta acagacgtca agctttttca tacagaccgt
      481 ggaaaggaat ttgatagcca aaccattcat gagattctga atggttttgg aattactcgt
      541 tcattgagta ggaagggttg tccgtatgat aatgccgttg cggaatcaac ccataaatct
      601 gtcaaagtag aattcgtgca tcaataccaa tttgagacac tggcacagct acgtctagaa
      661 ttgtttgatt atgtgcattg gtggaactat ctatgcttac atggcacgtt ggcgtatgaa
      721 acaccgatcc aaattcgaca acagagattg gcgaagcgaa tccttgataa tgagcgcgga
      781 tctgatacct ctggagaggc agcgtaattg aatgattgtg cttctgccgg agaaaatcag
      841 atccgaggat gctcattgtc aagggcaatc ggagccataa caccgcagca ttcacaacac
      901 cttataattt ttgtcaaaaa aagtgttgcc attccaacca atctaatcga gtctttcaat
      961 aagcaaatta aaagatacag ccgtagaaaa gagcagtttc aaaatgaaga atcactagaa
     1021 cgctttctag tcagcatttt tgatacatac aatcaaaaat ttctaaacag aagccataaa
     1081 ggttttcaac aggtaaccga tacattagtt tcaatgttta ctgagtaact aattattttg
     1141 caggaggaca atttatttac acaaaattat tgacgctccc ttaacaataa atgaagactt
     1201 ttttattgtt aattgtttat ttttctatta ttagatatga aaatcgcatt tagataaaat
     1261 agaaaaatat gaatatattt taaatattaa gatgagagtc attaacttat gatagtagtc
     1321 aatttgcttt tcactaatta caaaatatgt gatataggaa gtttagttat tgttctcata
     1381 atgccatcct gtttttagat tatctagtaa tttttttgtt atttaaaatt aggagcagtg
     1441 ccaattgttt taattttaaa ggcttttttt atatcttcta aattagaaga tatttgtata
     1501 tcaatatgga atatattacc ttttttgtat ttttttatgt tatctttagc taaaacatca
     1561 aatacatgtc cttgaaattg tatcgaggca gctggattta gtttaaattg aggaaacttt
     1621 accacagctg attcaaaaca cttgtcacat ttttttattt ttttaccttc gccgattgta
     1681 aaattaagct agacaactaa aaaagtcatt tgtgctacac tcaaaatagt tccgtcgaaa
     1741 gaattataag gagtgagtac aaatgaccta tacccatctt acaccaactg aactcgtaat
     1801 gatagaagct tatttcaatc aatcacactc tgtttcaaaa gtagcccatc tggtacaacg
     1861 ttctcgacaa accatttata atgtctatcg ttttcttaaa tctggtggaa gcgcaataag
     1921 ctactatgaa caatataaga aaaacaaacg taactgcgga agacgtccga ttgtgttacc
     1981 agatgggcaa caagaataca ttcaaaaaaa ggtggctcaa gggtggactc cagatgtcct
     2041 tattggtcga gcagagtttc ctattgcttg ttcggtacgt acactatatc ggatgtttaa
     2101 agataaaacc tttgaccctc acgatttacc aatgaaaggg aaaagaaaac caaacggaca
     2161 taaagaaaaa agaggaaaac aagcttttcg ccgttcgatt caggatagaa caactgatta
     2221 tatacagttc aatcatgagt ttggtcacct agaaggtgac accattgtcg gtggaaaaca
     2281 taaaagtgcg gtgatcacgt tagttgagcg attatctaaa gtgatcatca ccttgaaacc
     2341 cgctggtagg caagctatag atattgagaa tagactgaat caatggtttc aatctgtacc
     2401 gaaacacttg tttaaatcca tcacatttga ttgtggaaaa gagttctcga attggaaaaa
     2461 gattagtaat accaatgata tttcgattta tttcgctgat ccaggaacac cttctcaacg
     2521 aggactaaat gaacattcga atggcttatt acgtaaagat ggcttatata aagctatgga
     2581 ttttaataag gtatccgaaa cctttatcca atcggtggca tcaaaacgaa atcatattcc
     2641 tagaaaatca ttacactatc gcacaccatt ggaagtattt ttgagttacg taggtaaaga
     2701 tgatttgtct agcttaattt gacaaacgaa actttgtaaa aatattcgat tgaatattct
     2761 atttggcacg actcacttgg cagtatatgt atgtcaatat ttttcatctg tttcataggt
     2821 atttcaaaat ctaaactatt aaaaacatat aattccctgt aattatttac atctaactct
     2881 actaaattta tctttggaac aatagatcct ccacccattc caccataata aaaaaaatct
     2941 tgttctctat caaaatagca catattaagc tcagtttgtt tatcatcctc aataatttta
     3001 taaatcaaac ctatataatc atgaatgctg gcaaaaattt tttttaagtc aagttctaaa
     3061 tcttcttcga aaacacattt aatttctcct actgataatt gatactctat attacatgac
     3121 ttaattagtt ttttagatcc cccctccaga taggcatatg tttcaataat tatgttcttt
     3181 ttattgcttg gcaaatttcc gttatttatt gcataaatta aaaatgactg tctatttagc
     3241 ccataatcta atacaacttc ttcatactca tatttcttta aatatttaat atgaaaatat
     3301 gctgaattaa tcaaaactcg agtgttactg ttgttattta ttgttgttct attgtgtata
     3361 aaattgtata ggttgtcata ttttcttggt ttagtgaact actcaccact tagctaaacc
     3421 taacggtttc ttacgtttga agtgggagct tcttgggaa
//
LOCUS       DAYYEF010000123         3376 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000123 DAYYEF010000000
VERSION     DAYYEF010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.129"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            88..327
                     /locus_tag="ACHA1B_002827"
     CDS             88..327
                     /locus_tag="ACHA1B_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703533.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            474..>3376
                     /locus_tag="ACHA1B_002828"
     CDS             474..>3376
                     /locus_tag="ACHA1B_002828"
                     /inference="COORDINATES: protein motif:HMM:NF033903.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /protein_id="HFM8703534.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQT"
BASE COUNT         1229 a          580 c          694 g          873 t
ORIGIN      
        1 gtacttgttg tatcaaaata agccagtaga acaaccaaac cagtagctag taatgacaat
       61 aatactgagg aatcggatca ttatggtatg attgatattt ctcttccaga agatcttaag
      121 ccagatcctg taacaattgg caatagtgtc atgatttttg attcattaga tgaagctatg
      181 tcatatggtt ggaaagaaat taaggatgaa ggtagtaatt ggtatggcat gagatttggt
      241 gatggtgaag ttgccaaaaa agctggtatt ccaattggga aatggacagt tgatttccac
      301 gaagcaggtt ctttttttgt tctgtaatta tagtgggagg gtaaaatcat tgatgaaatg
      361 tgttcagata agagcgccag ataaaaatag aagagacagt tcacgtcgtt atcacttttg
      421 gtaacggcgt tttgttttat tatataaaat tctcaggaaa aggaggaatt cttgtgtatg
      481 caaaaacgaa aatgaattgg ttgaaagcac tcgcattggt ggctttttct caattctgtt
      541 tcttggtggg aactgctcaa gcacatgcag aagaaacgac ggctatacaa cctacgatgg
      601 aagccattgc ccaagtcgct tctgaagtga cagaagtcca accagcagaa gccggggtcc
      661 cagctggtga agccactgtt gaacaggccc ctgtgacaga agcgccaacg gtcaattcca
      721 aaacgactct cgatcagacg attggggaaa cacaacaccc agggaatagt cctggtactt
      781 cacaaccagt tgaagaaact gcctcaatta caacccctgc ttcagaaacg tccactctag
      841 aaggagaaaa agctgccgaa gcaacgcctt ctgtgcagcc agagtcttct gagaaacaag
      901 cggaagaaaa gaaacgaata gaagaaacag tggaacaacc agcggctact gctgacaaag
      961 aaggaaaaaa tgaggaaaac gttgaaaaaa caatctcttc aaccgcagct agtcaaaatc
     1021 aaccaacgaa accaaacaaa gaatctacgg ctagtattga aaatcaaaag aaaaaagagc
     1081 agaacattcc aaaaacaggt acacctacac tgttagtaac agtaccaacc aatcgttcgg
     1141 ttcgtgttcg ccgtgcaacc aatgcagctg ttttaggtgg tcggaaaatt gattggggcg
     1201 aaaatattgg tgttacttct agtccgaaca atctaaactt cactttaaat tatatggttc
     1261 gttttgagat taatggacaa gtggcgtttt gtattgagcc tggtgtctca gccgcagaag
     1321 gtcaagttta tacagctact gctttgaaaa actatttgaa aaattcaaat gtacggaaaa
     1381 aaacaagctt gatctcttat ttaggatatg tcacaaataa agacaaatcc gatgaacaat
     1441 acattgcggc acaatttatg atttgggaag ctttgggcac aaaaatccca atcaaaaata
     1501 tccgtgttga ttatgatcgt cgaaaagcag aaattcaacg tttgattaat aactttggtg
     1561 aaaaagcaac ttttaataat caaacacata cggtaaaaat tggcgaaacg ttgaaagtaa
     1621 agaataaaaa tgattttttg aaatatgtga aagacattca aaaaccaaaa ggtgtcaatg
     1681 tatctattca cggcaatgaa gtatggatta cagtcacaaa agaggcaccg gataaagcaa
     1741 aaattcaatt gaataaaatt aaagttcaag gtgcgccatt agcctatcgt cgtccaggag
     1801 ctcaaacaat tggtgtgtta catccaacag aacctaatgc gtctgttatt aatttacaaa
     1861 ttctaaaaca aggaaacatt cgtgtgttta aagaagatgc ggaaactggt gtgaaagcac
     1921 aaggtgcagc ttctttagaa aatgcggtct atggtttgta tcaagcagat gggaaaaaga
     1981 ttaaagaaat taccttgaaa aaaattaacg gcaaagtaca ggcagaaatt aaagatcttg
     2041 atcctggcaa atatgtttta aaagaaatca aagcgccaaa aggttatgtg ctttctgatg
     2101 aagcaattga aattgttgtt gaacctggaa aaactgtcaa tgcgaccgca aaagatcaag
     2161 tgatcaaagg aaccattgat ttagtgaaag ttgctaataa agatttagtc gattcaacga
     2221 atccagataa caaaccaaaa ttagctggca ttgaaatcac tttgacgtca aaaacaactg
     2281 gcaaagtggt gaaaaccgtt gtgacagaca atgatggtta tgctactttt ggtaaaaata
     2341 ccgttgtctt tgatacgtac attctttctg aaaccaaagg aaaagaaggg tataaactat
     2401 ttgaaccact tgaagtcaca atttctgaaa atgggcaaac tttccattat gttttagaag
     2461 ataaagtaat tgaacaacgt cttaaagtgg tgaaagtgga tcaagaaaca ggaaaagtga
     2521 ttccacttgc taatacagaa ttcaagattt ttgatacttt agccaatcgt tatgtcacaa
     2581 tggagattcc aaatgataca gaaacaacgg atatctttaa aaccaatgaa aaaggctttt
     2641 tcctaactaa cggtacactt acttatggaa aagatcgcta tcgtttggaa gaaatcaaag
     2701 cccccgtaaa ttacgttttg aatcaaaacc cattagtgtt ctcgattacc aatgatacag
     2761 aaccgatcaa agtgatccat tttgcgaacc gtcaagcacg gaaaagtgta aaattattca
     2821 agtatgaaga atggaacaag aagaaaacgc cgctcgcagg tgtgaacttt accttgtata
     2881 acggtaaaaa tcaagcaatt ggtgaatata ccactgatca aaacggggaa attttagtga
     2941 aaggtctagt tgccgatgac tattacttct tggaaaatgc cccattagaa agtttccaac
     3001 caaatacaga taaacaagca ttcacggttg cattcaaaca aaatgcgcca gatgatgggg
     3061 aaacgttagt ggtttctgta cgtaattact tgattccacc aaaactagaa acacaagcgt
     3121 caaataaagc cgatggtgaa aaagtggttg atccattaga aacgatcgtc attaaagaca
     3181 gtgtttctta taccaacttg tttgtcggaa aagaatacac catttcagga gtattgatga
     3241 acaaggcaac gaatgcgcca attttacaag atggcaaaga aatcacaagt accttggcct
     3301 ttattgcaga caaagtcaat ggcacaaaag accttgaatt tgtggttaat gctagtgttc
     3361 tgaaaggtca aacgat
//
LOCUS       DAYYEF010000124         3356 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000124 DAYYEF010000000
VERSION     DAYYEF010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3356
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.130"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..220)
                     /locus_tag="ACHA1B_002829"
     CDS             complement(<1..220)
                     /locus_tag="ACHA1B_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703535.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRV"
     gene            complement(243..1718)
                     /locus_tag="ACHA1B_002830"
     CDS             complement(243..1718)
                     /locus_tag="ACHA1B_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HFM8703536.1"
                     /translation="MEAHFFKYRGRRIRYFNRYLWICYYGFFLFPFLILLGWFSWKVF
                     YPRLSTYSNWQMYLIPGISIVLYLLLVSGLILGLMRWSRLKEGYFASVYWRQLLARML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGSLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVGVFKGHVFYKTNEDMII
                     CLRNALKEMNQRYVYMKTMKEPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMETRN
                     RVDKLIQPLVLKGRQAGMYVILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(1743..2099)
                     /locus_tag="ACHA1B_002831"
     CDS             complement(1743..2099)
                     /locus_tag="ACHA1B_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703537.1"
                     /translation="MNSDKTNQTLREIVACCQNIQQLIEYFGDNPTIFVQTNEYICAV
                     IGQCMFLRDLVRFSLPYQWKQNHQEEVWIRVVRICNMCAHPYKNRLNLFRLWFFVKCD
                     IPVLVAFCQKFLAQEK"
     gene            complement(2166..2618)
                     /locus_tag="ACHA1B_002832"
     CDS             complement(2166..2618)
                     /locus_tag="ACHA1B_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703538.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKAEAPTNNPNPKQPQEKGLNQKQLSVDSKEKGKK"
     gene            complement(2620..2985)
                     /locus_tag="ACHA1B_002833"
     CDS             complement(2620..2985)
                     /locus_tag="ACHA1B_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703539.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIEEVL"
     gene            complement(3084..>3356)
                     /locus_tag="ACHA1B_002834"
     CDS             complement(3084..>3356)
                     /locus_tag="ACHA1B_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFM8703540.1"
                     /translation="QAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVKPEQ
                     RVKAATVVPMLPKTGEQTSSILMVLGLVVLVIVLGITLYKVRKAKD"
BASE COUNT         1077 a          731 c          439 g         1109 t
ORIGIN      
        1 ctactcgata atgatacaat cgagtcaatc gttctatatc ttttttcgtt agcaatactt
       61 gattaataac ttttcctgta aaaacacgtt ctttgcgcaa aaagcggtaa tcagttactt
      121 gttcaatacg attcaaccaa tcataaaacg ttctggaaga aagagaagga ttaatcattc
      181 gtattgctgt agctactcga taataacaac tctctgccat ttaacttcac ctccttagtt
      241 gattacaaaa tatgcgcatc agaaaaactt gttccttttg gatcttttgc taaatacatt
      301 tggcgctcta gttgttcttg taacaactga ttatcatctc ccatcgtttg atcttgacta
      361 tcctctttta ctgtaaaatc atagacaatc atttcagtaa atttctcaaa ttctttgata
      421 aagtgatagt ctttgtaaac aaatggcgca aagaactcta caggtacatc aaatcctgga
      481 aaagcatacc cacgaccagg ttgatctttg ttgtaaaatg gcttattttt aaaatcttca
      541 ccaaaagtca ttaaatagcc aatcggagat aatcgaccaa cagaaatacg gaacgttaaa
      601 ttatctcgaa caccacttgg aaaatattcc gcatctggtc gttgcatcgc taaaataacg
      661 tacatccctg cttgacgacc ctttaatact aatggctgaa tcaatttatc gactctattt
      721 cttgtttcca tatccaacga accataaaaa gctgcccatt catcaaaaaa aataaaatgc
      781 ggtggtaacc cataataagc ataatttttc cctggttcat acttaggctc tttcatcgtt
      841 ttcatataga cataccgttg attcatttct tttaacgcat ttcgtaaaca aataatcatg
      901 tcttcatttg ttttgtaaaa cacatgtcct ttaaatacac caacgtcacc taatgccgct
      961 aaatctgccg cttttccatc gcaaatatct actgtcccaa cacttaaaca agcttgaatt
     1021 aaagaataca ataaataggt tttcccacca ccgattgcac cagcaatcaa catatttggc
     1081 gattgatcat atacccaatc caaagttttc attaaatgaa tacgtccatt ttctgctata
     1141 cattgatcaa taggaatccg accagaatct gaaagaaata cataattgat tcgggctttt
     1201 tctctttctt cacgaattaa atcacgcaaa aatacttcag ataacaaact acccattttt
     1261 aaaaatcgtt cgtgaaaacg cccaccatct aaaggaaaag aaaccactaa ttcttgtttc
     1321 ttttgataaa aataaacttt tggtaatctc attttttccc ttgtttgttt ctcactaact
     1381 tgtttctttg tataaacaaa ccgattatca attaacattc gagcaagtaa ctgacgccaa
     1441 taaacagagg caaaatatcc ttcttttaat cgcgaccaac gcatcaaacc taaaatcaat
     1501 ccactaacca gcaacaaata caacacaata cttattccag gaataagata catttgccaa
     1561 tttgaatacg tacttaaacg tggataaaat actttccaac taaaccaacc taacagaatc
     1621 aaaaatggga acaaaaagaa accataatag caaatccata aataacgatt gaaatagcga
     1681 attcgccgac cacgatactt gaaaaaatga gcttccaatt gtcacattcc tcctttctgt
     1741 ttttacttct cctgtgctaa aaacttttga caaaaagcaa ctaatactgg aatatcacat
     1801 ttaacaaaaa accataatcg aaaaagattt aatcgatttt tatatgggtg tgcacacata
     1861 ttacatattc gtactacacg aatccaaacc tcttcctgat gattttgttt ccactgatat
     1921 ggtaatgaaa aacgaacaag atcacgtaaa aacatacact gcccaatcac cgcacaaata
     1981 tactcatttg tttgtacaaa aatcgttgga ttgtctccaa aatactcaat caattgttgg
     2041 atattttgac aacaagccac gatctctcga agtgtttgat tggttttatc tgaattcaaa
     2101 atctcccctt ccttctacct tagataaaaa gaataggaag acttcttcct actctttcaa
     2161 aaaacttatt ttttcccttt ttccttagaa tcaacactta gttgtttttg attcaaacct
     2221 ttttcttgtg gttgtttcgg attaggatta tttgttggag cttctgcttt ttctaatcct
     2281 ttcgcataaa tcactaaatc tgaatattca cgattgccat cttgtgctgg aatatatacc
     2341 acatgatatt ctggatcaat taatttcaca ggatcacgtc gtttaaaacc agtcagatct
     2401 acatctgctg gaaacttaac tcgtcgtgca atcttcggtt catctggatt tccaaagact
     2461 aattgtgctc gctgtgatcg aatttctccc gtataatcgc ctgtttcatt atcaaataca
     2521 cgatcagact cttctaatgc gccaaagcgt acggctccta aacaagtttc atctaatgct
     2581 tctgtaatat cataattatt tggaaatttt aatcccatct tacaaaacct cctcaatttt
     2641 tacgccagtt aaaaagacac caacatcttg atagccagtt gttcgacgct ctgtttgtcc
     2701 catatcattt gtttcacgac tattcactcg ttctttacga aaaacaaaat aagcttcttc
     2761 aaatgaaata cgcacctctt tttctggtaa tcgtaatctt ttatcctctt cagctgtgag
     2821 ataaacaaaa aaagcaggct gttcttctcg cgaacattct gcttgtaatt gaacatatcg
     2881 cccagacaca ccattaattt cctttggtgg attaggttcc cgtgaaccca ataaaaatac
     2941 ttgacctaaa aactctttct tcatacgcaa tgctttttct gccataaagt ttttcctcct
     3001 cttaaaaacc aaaataaatt ctaaatattt ctacattaca atcaaacaag cggttaaaaa
     3061 tcctaaccgc ttgttcctca tgcctaatct ttggctttac gtactttata aagtgttata
     3121 cctaaaacaa tgactaatac tactaatcca agaaccataa gtatactact tgtttgttcg
     3181 cctgtttttg gcaacattgg tacaacagta gctgctttaa cccgttgttc tggtttcact
     3241 ggttgcggtg gttttggcgc ttccacaatt tgaaccgttt gatctttgtt tgttagatct
     3301 acattgtgtt tcgccacttc ttcaaacgtt tctttctcat cttccgtttt cgcttg
//
LOCUS       DAYYEF010000125         3342 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000125 DAYYEF010000000
VERSION     DAYYEF010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.131"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..205)
                     /locus_tag="ACHA1B_002835"
     CDS             complement(<1..205)
                     /locus_tag="ACHA1B_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703541.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRL"
     gene            complement(228..1703)
                     /locus_tag="ACHA1B_002836"
     CDS             complement(228..1703)
                     /locus_tag="ACHA1B_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HFM8703542.1"
                     /translation="MKAHFFKYRGRRIRYFNRYLWFCYYGFFLFPFLILLGWFSWKVF
                     YPRLSTFSNWQMYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLVRML
                     IDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGHLLS
                     EVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPNMLI
                     AGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEEMII
                     CLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDMEARN
                     RVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYLMTF
                     GEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYDFTV
                     KEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(2152..2604)
                     /locus_tag="ACHA1B_002837"
     CDS             complement(2152..2604)
                     /locus_tag="ACHA1B_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703543.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(2606..2971)
                     /locus_tag="ACHA1B_002838"
     CDS             complement(2606..2971)
                     /locus_tag="ACHA1B_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703544.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(3070..>3342)
                     /locus_tag="ACHA1B_002839"
     CDS             complement(3070..>3342)
                     /locus_tag="ACHA1B_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HFM8703545.1"
                     /translation="QAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVKPEQ
                     RVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
BASE COUNT         1084 a          709 c          435 g         1114 t
ORIGIN      
        1 acaatcgagt caatcgttct atatcttttt tcgttagcaa tacttgatta ataacttttc
       61 ctgtaaaaac acgttctttg cgcaaaaagc ggtaatcagt tacttgttca atacgattca
      121 accaatcata aaacgttctg gaagaaagag aaggattaat cattcgtatt gctgtagcta
      181 ctctataata acaactctct gccatttaac ttcacctcct tagttgatta caaaatatgc
      241 gcatcagaaa aacttgttcc ttttggatct tttgctaaat acatttggcg ctctagttgt
      301 tcttgtaaca actgattatc atctcccatc gtttgatctt gactatcctc ttttactgta
      361 aaatcataga caatcatttc agtaaatttc tcaaattctt tgataaagtg ataatctttg
      421 taaacaaatg gcgcaaaaaa ctctacaggt acatcaaatc ctggaaaagc atatccacga
      481 ccaggttgat ctttgttgta aaatggctta tttttaaaat cttctccaaa agtcattaaa
      541 taaccaatcg gagataatcg accaacagaa atacggaatg ttaaattatc ccgaacacca
      601 cttggaaaat attctgcatc tggtcgttgc attgctaaaa taatgtacat ccctgcttga
      661 cgacccttta atactaatgg ctgaatcaat ttatcgactc tatttctcgc ttccatatcc
      721 aacgaaccat aaaaagctgc ccattcatca aaaaagataa aatgcggtgg taacccataa
      781 taagcataat ttttccctgg ttcatattta ggatctttca tggttttcat ataggcatac
      841 cgttgattca tttcttttaa tgcatttcgt aaacaaataa tcatttcttc atttattttg
      901 taaaacacat gtcctttgaa tacatcgacg tcacctaatg ctgctaaatc tgccgctttt
      961 ccatcgcaaa tatctactgt cccaacactt aaacaagctt gaattaaaga atacaataaa
     1021 taggttttcc caccaccgat tgcaccagca atcaacatat ttggtgattg atcatatacc
     1081 caatccaaag ttttcattaa atgaatacgt ccattttctg ctatacattg atcaatagga
     1141 atccgaccag aatctgaaag gaatacataa ttgattcggg ctttttctcg ttcttcacga
     1201 attaaatcac gcaaaaatac ttcagataac aaatgaccca tttttaaaaa tcgttcgtga
     1261 aaacgcccac catctaaagg aaaagaaacc actaattctt gtttcttttg ataaaaataa
     1321 acttttggta atctcatttt ttcccttgtt tgtttctcac taacttgttt ctttgtataa
     1381 acaaaccgat tgtcaattaa cattcgaaca agtaactgac gccaataaac agaggcaaaa
     1441 tatccttctt ttagtcgcga ccaatgcatc aaccctaaaa ttaacccact aaccagcaac
     1501 aaatacaaca caatacttat tccaggaata agatacattt gccaattcga aaacgtactt
     1561 aaacgtggat aaaatacttt ccaactaaac caacctaaca gaatcaaaaa tggaaacaaa
     1621 aagaaaccat aatagcaaaa ccataaataa cgattgaaat agcgaattcg ccgaccacga
     1681 tacttgaaaa aatgagcttt caattgtcac attcctcctt tctgttttta cttttcctgt
     1741 gctaaaaact tttgacaaaa agcaactaat acaggaatat cacatttagt aaaaaaacat
     1801 aatcgaaaaa gatttaatcg atttttataa gggtgtgcac acatattaca tattcgtact
     1861 atacgaatcc aaatcacttc ctgatgatct tgtttccact ggtacggtaa tgaaaaacga
     1921 acaagatcac gtaaaaacat acactgccca ataaccgcac aaatatatgc atttgtttgt
     1981 acaaaaatcg ttggattgtc tccaaaatac tcaatcaatt gttggatatt ttgataacaa
     2041 gcacaatctc tcaaagtatt tgattggttt tatctgaatt caaaatctcc ccttccttct
     2101 atcttagata aaaagaatag gaagactcct tcctattctt tcaaaaaaac cttatttttt
     2161 ctctttttcc ttagaatcaa cacttggttg tttttgatct aaaccttttt cttgtgattg
     2221 tttcatatta ggattatttg ttggagcttc tactttctct aatcctttcg cataaatcac
     2281 taaatctgaa tattcacgat tgccatcttg tgctggaata tataccacat gatattctgg
     2341 atcaattaat ttcacaggat cacgtcgttt aaaaccagtc aaatctacat ctgctggaaa
     2401 tttaactcgt cgtgcaatct ttggttcatc tggatttcca aaaactaatt gtgctcgctg
     2461 tgatcgaatt tctcccgtat aatcgcctgt ttcattatca aatacacgat cagactcttc
     2521 taatgcgcca aagcgtacgg ctcctaaaca agtttcatct aatgcttctg taatgtcata
     2581 attatttgga aattttaatc ccatcttaca aaacctcccc aatttttaca ccagttaaaa
     2641 agacaccaac atcttgatag ccagttgttc gacgctctgt ttgtcccata tcatttgttt
     2701 cacgactatt cactcgttct ttacgaaaaa caaaataagc ttcttcaaat gaaatacgca
     2761 cctctttttc tggtaatcgt aatcttttat cctcttcagc tgtgagataa acaaaaaaag
     2821 caggctgttc ttctcgcgaa cactctgctt gtaattgaac atatcgccca gacacaccat
     2881 taatttcctt tggtggatta ggttcccgtg aacccaataa aaatacttga cctaaaaact
     2941 ctttcttcat acgcaatgct ttttctgcca taaagttttt cctcctctta aaaaccaaaa
     3001 taaattctaa atatttctac attacaatca aacaagcggt taaaaatcct aaccgcttgt
     3061 tcctcatgac taatctttgg ctttacgtac tttataaagt gttataccta aagcaatgac
     3121 taatactact aatccaagaa ccataagtat actacttgtt tgttcacctg tttttggcaa
     3181 cattggtaca acagtagctg gtttaacccg ttgttctggt ttcactggtt gcggtggttt
     3241 tggcgcttcc acaatttgaa ccgtttgatc tttgtttgtt agatctacat tgtgtttcgc
     3301 cacttcttca aacgtttctt tctcatcttc cgttttcgct tg
//
LOCUS       DAYYEF010000126         3221 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.132, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000126 DAYYEF010000000
VERSION     DAYYEF010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.132"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            301..585
                     /locus_tag="ACHA1B_002840"
     CDS             301..585
                     /locus_tag="ACHA1B_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703546.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            588..1004
                     /locus_tag="ACHA1B_002841"
     CDS             588..1004
                     /locus_tag="ACHA1B_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703547.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1141..1860)
                     /locus_tag="ACHA1B_002842"
     CDS             complement(1141..1860)
                     /locus_tag="ACHA1B_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HFM8703548.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLE
                     FTFSSLTSDLPKISLRNWLEE"
     gene            2544..2630
                     /locus_tag="ACHA1B_002843"
     CDS             2544..2630
                     /locus_tag="ACHA1B_002843"
                     /inference="COORDINATES: protein motif:HMM:NF033608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HFM8703549.1"
                     /translation="MFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(2932..>3221)
                     /locus_tag="ACHA1B_002844"
     CDS             complement(2932..>3221)
                     /locus_tag="ACHA1B_002844"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703550.1"
                     /translation="EYRRQRSDFISRKIVRLEKEKMEKFPYEYFQNLEKLEQAIQAIK
                     FDLTDEKLLEYKNMTPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT         1074 a          599 c          503 g         1045 t
ORIGIN      
        1 aaaaaaaatg tcgtttgaaa aactaaataa atttttgatc gtgcattttt aaatttggtt
       61 atcgattaca cgtgcagcac tcccccccga attttaaaga gcataaggaa acgtgtaccc
      121 actttctaaa aaaagtgggt agataggctg tgcctatcac gtttctcaga aaaaaatttg
      181 atatcacttt ttcgccatcg tgggtagctt atgtatagca ttttggcaaa aaacagctat
      241 acaaatatag tatttgtatg gtatacataa attatacata attgcaaaag gagatttttt
      301 atggacattt tagttcggaa tattgatcca aagtttgttg caacaataga caaacgttgc
      361 caagaactca cgaataaaac aggagaaaaa tggagtcgaa ataaatatct aaaagtttta
      421 atcgaaagtg attttgaccg tcaacttacg acttacaaaa aagaccaatt cgatttattg
      481 ctcgataaat ttattgctat ccaaacagaa aatactcaaa tattaagcga gtatgtctac
      541 acaaataatc aaatcattga aatgcttatc ggaggaatga tataaccatg agaaaaactt
      601 ctgtccaaaa acatgttact ttgtacccta gtcatgttga cgttttagat tccatcatcg
      661 aaaaaaatcc agatatcaat aactactcgg aagccattcg ctttttatgt atgagttatg
      721 aacccgatac caacacgacc actaccagca atcaggcaaa actaaatgct atgggaaaag
      781 aaatttccat catgactgaa atcatcgcag aatttgctga tttatatcta aaagatacag
      841 gcgttcttat tggcacaaat tctaaagtat atcaagaagt gaaagaaaaa atcgaagcta
      901 aactaaatcc atcaaatcga aatcgaccaa agaatcatca aaaagaaacc agtcaaacag
      961 tcacttctag aaatttcgac ccaacaaatt ttctaaaacg ataaaaaaca gataggagtt
     1021 attcctatct gttttttatt tagaagcccc atacaatatg ctagaatgta ctagcaatct
     1081 tagtcggttg taagggactt gtctacttgc ttaatgtaag gggggcgagt tcttttttat
     1141 ttattcttct aaccagttac gcagagaaat ctttggcaaa tctgacgtta ggcttgaaaa
     1201 agtaaattct aatttggcga ttttattgcc cttttttgct tttatttttg tgactttaag
     1261 atcattgaag tattttttta gttctcgtaa tgcaggattt aatacttttt gatcaatgtt
     1321 acccatttga tagtattctg ggatatccat taagctccta aactcttcaa tacgaactac
     1381 ataataacca gtagaacggt actgcataag cagtcggaat agagtttttg catacgtaga
     1441 acgcaacgac gtgaaagcag ataattcaaa tctactaaat tcagctgtta aaccattaat
     1501 aatatattct aggtccggat taacactgac ttcaacaaac ttttttgttt tattgatttc
     1561 aaaaccagta aacaaaacaa agtagcgaat agaatcctca tcttcagtac ggtaagtaag
     1621 attaagcata tctttataga gcttttctaa atcaccgaca aaggcttttg tagcagtcat
     1681 cttataatca cttaactctt ttaattcctc gaaagaaaat ctaacttttt tcaaaccacg
     1741 atctttcata cgagcgcata atgcaaaaaa taaatccatc tgcttagcat tgaaattttt
     1801 cagcggtact aaattcaatt cattttgata tttgactgtt aattccgttt tttcatccat
     1861 tcctttcttc cccccttaca aataaataat aacctttaac aaccaactcg taaataggtt
     1921 ggttgttatt atacaaaagg atattagtac tcagataaaa agttgttagt actcagataa
     1981 aaagttgtta gtactcagat aaaaagttgt tagtactcag ataaaaagtt gttagtactc
     2041 agataaaaag ttgttagtac ccttctgtat ccgttgggag agtaaggctc aactgccccc
     2101 taaaaagggt tctaaaaaat ctttaaaaaa taaataaaat aaacgcgcgc gcgcgagcaa
     2161 aatttcccgc caaaaaatca cccacttttt aaaataaaca ggttcgcgca tgatattaaa
     2221 ctgccaatct agctccctat ggtcgctgta agaaggagtg atcgctacgc tctcacattt
     2281 tacttgcagc agtcgccttt aggctccttc gccaaaaata attcattagg gactcctttg
     2341 tggcgtcctg agagctcgtc taagccgttc taagacaaga ttcgataaaa actatgtcct
     2401 tcgttctaaa gcgccttaca ggcggtcagg gcaagcccta acaaccccaa ggcaataaaa
     2461 aacttaggct tatttttgct tttttattgt ataattgatt gtcgcctatc cgacagtctt
     2521 gcgactggaa ggaggtgtgt ttcgtgttca ctaactttat ttgctccctt cttgttgggc
     2581 ttttaagcgc tttgttcagt tactggttga ataaccgaaa caagaagtaa aacttaatta
     2641 aggcgactca gcccacaaaa aaagccccag agaatccgac ctctctgggg ctttcgtgtg
     2701 tttcgtgttc acttatttgc aatcaaatta taacagaaat aaatatttat ttcaaaaata
     2761 tcctacaaaa gtctaaaatc cgtaattatt tcttatatgc aacatttaca aataaagtcg
     2821 ctctgagagc tcgtattttt cgatttaaga cgttttattt agtttttggt gtatttcatt
     2881 ggtccaagct aaaaaactct tagaagcgat tttagagcca tttaaaccca cttaattata
     2941 ttctccatga aattcgctcc atgcgtcaaa agctgcgtct gaaattccgc cgtcttcgtt
     3001 cactagttgc attaattttt ccaacgatcg ttttctttcg ggtgtcatat ttttatattc
     3061 caacaatttt tcgtctgtta aatcgaactt gattgcttga attgcttgct ctaatttttc
     3121 taagttttga aaatattcgt aaggaaattt ttccattttt tctttctcca gtctcacaat
     3181 ttttctagaa ataaaatcac ttctttgccg tctatactct c
//
LOCUS       DAYYEF010000127         3219 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000127 DAYYEF010000000
VERSION     DAYYEF010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.133"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1438
                     /locus_tag="ACHA1B_002845"
     CDS             <1..1438
                     /locus_tag="ACHA1B_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HFM8703551.1"
                     /translation="SKKNQPKDIKDIVDTRMYKERDDLNYTLIINKDGNYSWRPLVLL
                     HPILYVDLVNCLTKEDHWEELKKRFSEFKKDKNINCYSIPVEASKGSKRTDLGETILN
                     WWEYFEQKSLAQNIKYQYCMFTDIADCYPSIYTHSITWAMYGKEKVKNDENKCSGSLG
                     DKIDKKISGMQHNQTNGIPQGSVLMDFVAEIVLGYVDLRLSKELKKLENLKDYKVLRY
                     RDDYRIFSNNRNDLEQIMKVLSEVLYDLNFKLNSSKTKLSDDIIIDSIKKDKLYWEEI
                     KASIRMNATNLDGDREIRYSINLQKHLLEIKKLADKHPNSGQLKKALSEFNKERIIKI
                     TSKPNDLLPLIGILVDIMINNPGSLPQCVLIIGQLLNFENESKAREIVEMIINKYALK
                     PNTEFMMIWFQRLTTIFGEMFDSVLSSEFVSKIKDPVSNQMFSVDWLNEDAKKSFYEG
                     TIKDEEKYIKMSKKIYITEFDDFNDYPF"
     gene            1776..>3219
                     /locus_tag="ACHA1B_002846"
     CDS             1776..>3219
                     /locus_tag="ACHA1B_002846"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity
                     [Evidence IEA];
                     GO_process: GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HFM8703552.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEE"
BASE COUNT         1183 a          505 c          583 g          948 t
ORIGIN      
        1 ttcaaaaaaa aaccaaccga aagatataaa agatattgta gatacacgaa tgtataaaga
       61 acgtgatgac ttaaactata cgcttattat caataaagat ggaaactatt catggcgtcc
      121 tctcgttcta ctacatccta ttctatatgt agatttggtt aattgtctca ctaaagaaga
      181 ccattgggag gagttaaaaa agaggtttag tgaatttaaa aaagataaaa atattaactg
      241 ttattctata cctgttgaag cttccaaagg ttcaaaaagg acagatcttg gtgaaacaat
      301 actaaactgg tgggaatatt ttgaacaaaa aagcttagct cagaatatta aataccaata
      361 ttgcatgttt actgacatcg ctgattgtta tccatcaatt tatactcact ctataacatg
      421 ggccatgtat ggtaaagaaa aagttaaaaa tgatgaaaat aagtgttcgg gctcacttgg
      481 cgataaaata gataaaaaaa tatctggaat gcaacacaat caaacaaatg gtatccctca
      541 gggttccgtt cttatggatt ttgtagcaga gatcgttcta gggtatgttg atttgagatt
      601 atcgaaagaa ttaaaaaaat tagaaaattt aaaagattac aaagtactca gatatagaga
      661 tgattataga atattttcaa ataatcgtaa tgatttggaa caaattatga aagtgttatc
      721 agaagtctta tatgatttaa attttaagtt aaattctagt aaaacaaaat tatcagatga
      781 tattatcata gattctatca aaaaagataa gctctattgg gaagaaatta aggcaagtat
      841 aagaatgaat gccacaaact tagatggtga tagagaaatt cgttatagta taaatttaca
      901 aaaacattta ttggaaataa aaaagttagc agataagcat cctaattcag gccaattgaa
      961 aaaagcactt tctgagttta ataaagaacg cattattaaa atcacttcaa agccgaacga
     1021 tcttttacca cttattggta tcctggtaga tatcatgata aataacccgg gttctttgcc
     1081 gcagtgtgtc ttaattatag ggcagttatt aaatttcgaa aatgagagta aggctagaga
     1141 aatagttgaa atgattataa acaaatatgc tttaaagcca aatactgaat ttatgatgat
     1201 atggtttcaa agattgacca ccatttttgg agaaatgttt gatagtgttt tatcatccga
     1261 atttgtatct aaaatcaaag atcctgtctc taatcagatg ttttctgtag actggctaaa
     1321 tgaagatgct aagaaatctt tttatgaagg gaccattaaa gacgaagaga aatatattaa
     1381 aatgagtaag aaaatatata ttactgaatt tgatgatttt aatgattatc ctttttaagt
     1441 gaaaatttag aatgaatata aaaaacatta caatctaatt tttttaaaaa aatgttatat
     1501 cggaagtaat ctcttgattt ctatactata agataagaaa accactattt aacaaggtta
     1561 ttcgaacctt attttaagtt acttattatt taatgtatcg aaaaaggtga aataggtttg
     1621 ttataataag aattaagtaa gacatgaatt gtctaagcaa atgtagctta tccatttcat
     1681 taaaatacat atggtgaaaa aacaagttca aatagtaact aattttttaa aaaactgatt
     1741 tataaaaaat acaacacgaa tgaggaaaat aaccaatgac agaacaaatc gaaaaaaatt
     1801 caaaaagctt atatcaggca ctgtggaatt ccgcagatat cctgcgttca aaaatggacg
     1861 ctaatgaata caagagctat ttactaggct tggtctttta taaatactta tccgacaaca
     1921 tgctgcggta tgtctccgtt ctattggagg aagaaacgga cgacctaaat aaagcacaag
     1981 acctttacgt tgaagcattt aaagatgcag atataaagga tgatctcttg tatgaactaa
     2041 aagatgagtt ttcatatacc atcgcacccg cattgacctt taccgcgcaa gtggcagcca
     2101 ttcatgatgg atcttttcaa ttagaagacc tggtacaagg tttccgtgac attgaacaat
     2161 ccagcgaaaa ctttgagaac ttatttgaag acattgatct gtattctaaa aaactggggt
     2221 caaccccaca aaaacaaaat aaaaccatcg cagatgttat gaaagaatta gaagggttaa
     2281 acatggcggg gcatgctggc gatgtcttag gcgatgccta tgagtactta attggccaat
     2341 tcgcatctga atccggtaaa aaagccggtg aattctatac cccacaaccg gtcgcaaaat
     2401 tgatgacaca aattgtttta caaggaaaag aagataaaaa aggcttttct gtttacgacg
     2461 cgaccatggg ttcgggctcg ttacttttga acgctaaaaa atattcccat caaccgggaa
     2521 ccatttctta tttcggacaa gagttgaata cgtctaccta taatttggcg cgtatgaaca
     2581 tgattttgca tggggttccc attgccaacc aacacttgca taatgcggat accttggatc
     2641 aagactggcc aacagaagag ccaacgaact tcgatggggt gctcatgaac ccaccgtatt
     2701 ctgcaaaatg gtcggctgat aaaggcttct tagatgaccc acgcttctct gcctatggcg
     2761 tattagcccc taaatcaaaa gcggactttg ctttcttatt acatggctac tatcatttga
     2821 aagatacggg cgtcatggcc attgttttgc cacatggggt gctctttaga gggggcgcag
     2881 aagggaagat acgcaaagcc ttgttagaaa atggtgccat tgacaccgtc attggcttac
     2941 ctgctaacat cttctttaat acgtccattc caacgaccgt aattatcttg aagaaagacc
     3001 gtgcgaaaaa agatgtgctc tttattgatg cgtcacaaga ttttgaaaaa ataaaaacgc
     3061 aaaatacgct acgagattac catattgacg ctattttaga ggcctataaa acccgtacaa
     3121 ttaaagacaa gtatgcttat gtcgcagaat ttgatgaaat tgtggagaat gattacaact
     3181 taaacattcc ccgttacgtg gatacctttg aagaagaag
//
LOCUS       DAYYEF010000128         2879 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000128 DAYYEF010000000
VERSION     DAYYEF010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.134"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(120..995)
                     /locus_tag="ACHA1B_002847"
     CDS             complement(120..995)
                     /locus_tag="ACHA1B_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFM8703553.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(1250..1334)
                     /locus_tag="ACHA1B_002848"
     tRNA            complement(1250..1334)
                     /locus_tag="ACHA1B_002848"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1298..1300),aa:Leu,seq:caa)
     gene            complement(1352..1423)
                     /locus_tag="ACHA1B_002849"
     tRNA            complement(1352..1423)
                     /locus_tag="ACHA1B_002849"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1389..1391),aa:Gln,seq:ttg)
     gene            complement(1433..1505)
                     /locus_tag="ACHA1B_002850"
     tRNA            complement(1433..1505)
                     /locus_tag="ACHA1B_002850"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1470..1472),aa:His,seq:gtg)
     gene            complement(1567..1651)
                     /locus_tag="ACHA1B_002851"
     tRNA            complement(1567..1651)
                     /locus_tag="ACHA1B_002851"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1615..1617),aa:Leu,seq:caa)
     gene            complement(1672..1742)
                     /locus_tag="ACHA1B_002852"
     tRNA            complement(1672..1742)
                     /locus_tag="ACHA1B_002852"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1708..1710),aa:Cys,seq:gca)
     gene            complement(1788..1859)
                     /locus_tag="ACHA1B_002853"
     tRNA            complement(1788..1859)
                     /locus_tag="ACHA1B_002853"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1825..1827),aa:Gln,seq:ttg)
     gene            complement(1871..1943)
                     /locus_tag="ACHA1B_002854"
     tRNA            complement(1871..1943)
                     /locus_tag="ACHA1B_002854"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1908..1910),aa:His,seq:gtg)
     gene            complement(1946..2019)
                     /locus_tag="ACHA1B_002855"
     tRNA            complement(1946..2019)
                     /locus_tag="ACHA1B_002855"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1985..1987),aa:Trp,seq:cca)
     gene            complement(2026..2106)
                     /locus_tag="ACHA1B_002856"
     tRNA            complement(2026..2106)
                     /locus_tag="ACHA1B_002856"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2070..2072),aa:Tyr,seq:gta)
     gene            complement(2108..2183)
                     /locus_tag="ACHA1B_002857"
     tRNA            complement(2108..2183)
                     /locus_tag="ACHA1B_002857"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2148..2150),aa:Phe,seq:gaa)
     gene            complement(2219..2291)
                     /locus_tag="ACHA1B_002858"
     tRNA            complement(2219..2291)
                     /locus_tag="ACHA1B_002858"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2256..2258),aa:Asp,seq:gtc)
     gene            complement(2301..2373)
                     /locus_tag="ACHA1B_002859"
     tRNA            complement(2301..2373)
                     /locus_tag="ACHA1B_002859"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2338..2340),aa:Val,seq:tac)
     gene            complement(2389..2460)
                     /locus_tag="ACHA1B_002860"
     tRNA            complement(2389..2460)
                     /locus_tag="ACHA1B_002860"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2425..2427),aa:Glu,seq:ttc)
     gene            complement(2475..2564)
                     /locus_tag="ACHA1B_002861"
     tRNA            complement(2475..2564)
                     /locus_tag="ACHA1B_002861"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2528..2530),aa:Ser,seq:gga)
     gene            complement(2604..2677)
                     /locus_tag="ACHA1B_002862"
     tRNA            complement(2604..2677)
                     /locus_tag="ACHA1B_002862"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2641..2643),aa:Asn,seq:gtt)
     gene            complement(2687..2802)
                     /gene="rrf"
                     /locus_tag="ACHA1B_002863"
     rRNA            complement(2687..2802)
                     /gene="rrf"
                     /locus_tag="ACHA1B_002863"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          846 a          668 c          539 g          826 t
ORIGIN      
        1 aaatcacttt tcccatttca ttctccttct tttttctact aaaataggcg caaccaaata
       61 atcatagtcc atttactatg tgtcatttgg ttgcgcctat agatagttac gcccttattt
      121 taatagattc ttgctagatg aattgccaaa tagatgattt cattttcttg aatggcaagt
      181 tgaaattgct gttcgatgat atctttaatc tttagtgctg tacaatacgc tttgctatgt
      241 ttaaatgttt cagtaaaaaa accaatattt tctactggcg tttcttcctg ataaatcaag
      301 cgtttaacca ggaatttgat atgaaccatt aagcgatgat aagtcagtga ttctttatca
      361 taaacgtttg aataggattt ttctagatgg gacaaaatcg tggtcgtcat ttctactatt
      421 tttaagctct ttaaactatt aggctctcct agctcagcat taatgatatg catagtgatg
      481 aatcctactt catttgaccc taactcggtt tgatatcgat gattgattcg ctcgaccact
      541 tctactgcta tatcatattc atttggataa aggaatctca tttctggcaa cataattgct
      601 gtgacatctc tatcttctct ttttcgttga atagcaaaat aaatatgatc tgtcaatgta
      661 atatagatat ttgaatctaa tggagaggag atcctagctg ttatcagttc aatcacttct
      721 tccgcaaaat ccataaattc gattggaatc tgcgagacta tctcactgaa tcgtttgatc
      781 ttttctttag aatctaatac aaataatttg tcagcatcct caacatcaaa tggcttactc
      841 actttagcag aaaagccaat ccctttcccc atcgcaattt tttctattcc atcgtcatcg
      901 atcaatacag cattatgatt cagctttttc atcacataca ccgttaattc acctcctcta
      961 tatgataaaa caaaacaact tgcagactcc ttcatacata tttttgtctc caaacaattt
     1021 ttaaagacaa aaaacgacct aagaaagaac cctttcttag gtcgtgccta attgaatagt
     1081 agcaccctac ataatttaca aaaatagttt aacacataat aaaagcgtta tcaatatctt
     1141 ttttactcgt tttatgataa tacttgtatc gaattgattt ggaggtaatt acataaaaac
     1201 aaaaaaaata tagcaactct ctataagaaa gttgctatat tgataattat accggcggcc
     1261 ggggtcgaac cggcacgtcc tcaacggaca ctggattttg agtccagcgc gtctgccaat
     1321 tccgccacgc cggcaaattt aaaaataata actggggtag ctggattcga accaacgcat
     1381 gagggagtca aagtcccttg ccttaccgct tggctatacc ccaagaataa agggcgaatg
     1441 atgggaatcg aacccacgaa tgccggagcc acaatccggt gcgttaacca cttcgccaca
     1501 ttcgccatca taaaagatgt tatttaattt ctcaataaaa aactaagatg aagacatctt
     1561 agtcaatacc ggcggccggg gtcgaaccgg cacgccctca acgggcactg gattttgagt
     1621 ccagcgcgtc tgccaattcc gccacgccgg caagttgatt tattagtact aaggcggtaa
     1681 ccggatttga accggtgatg aaggttttgc agacctctgc cttaccactt ggctataccg
     1741 ccattatact attatcaatc tataaaataa agaataaatt atagaaactg gggtagctgg
     1801 attcgaacca acgcatgagg gagtcaaagt cccttgcctt accgcttggc tataccccaa
     1861 gaataaaaag ggcgaatgat gggaatcgaa cccacgaatg ccggagccac aatccggtgc
     1921 gttaaccact tcgccacatt cgccatggca ggggcagcag gaattgaacc cacactaacg
     1981 gttttggaga ccgctgttct acctttaaac tatgccccta taaaatggag gagagtggat
     2041 tcgaaccact gaaccctaag gaacggattt acagtccgtc gcgtttagcc acttcgctac
     2101 tcctccatgg tggcgcggga cagaatcgaa ctgccgacac acggagcttc aatccgttgc
     2161 tctaccaact gagctaccgc gccatatttt aaaattatta attgaataac aagaacgacg
     2221 gttccgacgg gaatcgaacc cgcgatctcc tgcgtgacag gcaggcatgt taacccctac
     2281 accacggaac cagttcatta tggaggttaa cgggatcgaa ccgctgaccc tctgcttgta
     2341 aggcagatgc tctcccagct gagctaaacc tccaacattc aattaaaatg acccgtacgg
     2401 gattcgaacc cgtgttaccg ccgtgaaagg gcggtgtctt aaccgcttga ccaacgggcc
     2461 aggtaaattt gctacggaga gtaagggatt cgaacccttg agacagtttg gcaccatcta
     2521 catgatttcc aatcatgctc cttcggcctc tcggacaact ctccagagtg aaagaagctc
     2581 aatactcttt ctcaaaatga gaactccggc agtaggactc gaacctacga catcatgatt
     2641 aacagtcatg cgctactacc aactgagcta tgccggaata acatcagcgt ggcgacgtcc
     2701 tactctcaca aggggcaacc cctcactaca atcggcgcta agaagcttaa cttctgtgtt
     2761 cggcatggtt acaggtgtat ccttctcgct atcgccacca cactgtggtg ttatctttta
     2821 ttgagtaaat tttgttcact caaaactgga tttgaagtca cataagtttt tttccgagt
//
LOCUS       DAYYEF010000129         2859 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000129 DAYYEF010000000
VERSION     DAYYEF010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.135"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..345)
                     /locus_tag="ACHA1B_002864"
     CDS             complement(<1..345)
                     /locus_tag="ACHA1B_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703554.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
     gene            complement(417..1349)
                     /locus_tag="ACHA1B_002865"
     CDS             complement(417..1349)
                     /locus_tag="ACHA1B_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HFM8703555.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1552..2511
                     /locus_tag="ACHA1B_002866"
     CDS             1552..2511
                     /locus_tag="ACHA1B_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFM8703556.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            2644..2850
                     /locus_tag="ACHA1B_002867"
     CDS             2644..2850
                     /locus_tag="ACHA1B_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HFM8703557.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          913 a          452 c          446 g         1048 t
ORIGIN      
        1 atcttgtata agattactat taacgttttt tacaagtaca tcatctttta tatattttga
       61 aattaatgat agataaacct gagttgttcg ataggaactt tcttttacag ttggcttgta
      121 tttttcatcc catttagttt ttaattctcc aaaagttagt ggtaattctt catttcgttt
      181 tattttttct gcgatttttt cattcaaaag taagttagct tgattccaag cttggcgtga
      241 attgctagat aaagtaacgg acacttttct ctttttttca gttaagggat ccgtataacg
      301 ttcggtgtac ttaaattttt tgtcatttat tttttctaac cacattattt ctattccttt
      361 cgaatatacg ttcctattaa ttgttaaaag aaaaagcccg aaggcttttt atatatttaa
      421 tcttttgaca attctaaaga tcgtctatat tgttcagctt tagctaattt tgtaaatgtt
      481 actgttccat tataattttc taaaacaact ttctctattt cgtctagtga aactttgaaa
      541 aattcttttc tttgattaat tttattaact tcttgttttc taaaatgatt atgcaattta
      601 gtttccaaag acggagcgtc ctctgaaaaa atcatcgcat gaacgtcaaa ttcaaatgga
      661 accgatgcac tactcaattc ttttattcta tccataggtt ctaatcttct agtcatacca
      721 attttatata tgtcttcacc aaaagaccca atattactaa ttacatacac ataaccggct
      781 ctagtattta attctctttg taatacattt tcacgtataa cttctaattc ttttaatttt
      841 tcttccagtt cttgaatttt atttgcatat aattcttttt ccacatctgc attagctttt
      901 tgcatatatg cgattaattt ggaaatttca gaattgaatt gacgttgttc tttatcaata
      961 cgtttctttt cacgatcaat ttctctacga actttttcct cttctatcat ctgttctttt
     1021 attgcttttt gttgttcttt ttcttcggta attttcacta aataagagta atgaagttct
     1081 agttcttgaa gtttaaactc taaaagaccc ttccttaatt cagcattgtc attcttgaat
     1141 aaattattaa ttttatcaaa tatttttatg attttttccc tagtcgagtc tatattagaa
     1201 atagttagtt tattgagtaa tcctttcact tctgaatcaa atggaatgag catttttttc
     1261 tttaaattat ttttctctcg tttatttaaa ataagaggga cagaaacagc atcgtcaata
     1321 atatattcct tttcttttaa ttttaacaaa gaaagcttat tttttatttc agaagatgaa
     1381 gtttcttcta tatttgaaac gataagtgaa gaatagacat tttttaatgt ttcatcatac
     1441 ttttgattta tttcatcacg ccgattgtaa aattaagcta gacaactaaa aaagtcattt
     1501 gtgctacact caaaatagtt ccgaccaaag aattataagg agtgagtaca aatgacctat
     1561 acccatctta caacggatga acttgtaata atagagtctt atttcaaaat gaatcaatct
     1621 gttgctaaaa ctgcccattg cttgaatcgt tcaagacaaa cgatccataa agtatatctg
     1681 ttcttcaagc aaggaaaatc agccttagaa tattatcaac agtataagaa aaacaaatca
     1741 aactgtggta gacgtccgct tgttttaccc gaggaacaat cagaatatat tcaaagaaag
     1801 gttgttcaag gatggacacc cgatgtgatt gttggtcgtg cagcgtttcc tattagttgt
     1861 tctgctcgta ccatttatcg tatgttcaaa aaggggctat ttgattcttc tgacttaccg
     1921 atgaaaggca agcgtaaacc gaatggacat caagaaagac gtggaaaaca aactttccgc
     1981 cgctctattc atgaacgtga aaaggattat agccaattct caaatgagtt tggtcacctt
     2041 gaaggtgaca ctatcgtagg tctgaaacat aaaagtgctg taattacctt agttgaacga
     2101 ttatcaaaag ttatcatcac attgaaaccg tgtggtagac aagcgattga tattgaaaaa
     2161 aaattaaatc aatggtttga atctgtaccg aaaaacctat tcaaatccat cacttttgat
     2221 tgtggaaagg aattttcaaa ttggaaacag atcagtaatg tcaatgatat tgccatttat
     2281 ttcgctgatc caggaacgcc gtctcaaaga ggcctaaacg agaattctaa cggattgtta
     2341 cgtagagatg gtttattgaa atctatggat ttcaattcag tagatgaatt ttttattcaa
     2401 tctgtcgcat ctaaacgaaa taatattcct agaaaatcac tggattatcg aacacctttg
     2461 gaagtatttt tgagttacgt aagtattgat gatctgtcta acttaatttg acaattaaga
     2521 aagataaaat tgaacaactg gacgggcaaa ttgatgcctt gctttcagaa agagaaatat
     2581 tgatagaaga aaacaagcga ttgaaaaaga aagtagccca accaatgaag ggaggtggat
     2641 agtatgaaca atagaacctt tgatattttg aaatggatcg ctatagtagt tatccccgct
     2701 ttagcgactt ttgtcggtct tgtcggaaaa ggtgttaact ggcggtacac agatataacg
     2761 gtgatgatta ttacaggttt tggagcattt ctagggagta ttttaggtgt atcaaatcga
     2821 acgtataaga aaatttcatc agataaatag gaggataga
//
LOCUS       DAYYEF010000130         2787 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000130 DAYYEF010000000
VERSION     DAYYEF010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.136"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            130..576
                     /locus_tag="ACHA1B_002868"
     CDS             130..576
                     /locus_tag="ACHA1B_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Fur family transcriptional regulator"
                     /protein_id="HFM8703558.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            849..2201
                     /locus_tag="ACHA1B_002869"
     CDS             849..2201
                     /locus_tag="ACHA1B_002869"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HFM8703559.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            2372..2659
                     /locus_tag="ACHA1B_002870"
     CDS             2372..2659
                     /locus_tag="ACHA1B_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFM8703560.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT          979 a          456 c          551 g          801 t
ORIGIN      
        1 agtgaacgcg actgttttac gtcttttttc attaaaatac aataaaattg aattttcttt
       61 tcatgttaag tggattttaa aatgtaaaaa tagtatgata agacgagaat aacaacgtgg
      121 ggtgtttaca tggaaaataa gttagtcgaa gaggttatcg aaaagttaaa aaaagagaac
      181 attcgaatca cacctcaacg gtacgcggtt ttagaatatt tgattgaaca tcattcccat
      241 ccaacggctg atgagattta taaagcactt gaacatcggt ttccaaatat gagtgttgcg
      301 actgtttaca ataaccttcg cttatttact tcgattggat ttgttcaaga aatgaagtac
      361 ggcgatgctt ctagccgatt tgatttcagt tcaaagcgtc attatcatgt aatttgtgaa
      421 aactgcggta agattgttga ttttcattac ccagggcttg aagatataga aatggctgca
      481 agcagactga ctgattttga gattaatgaa catcggttgg aattgtatgg actctgtccg
      541 gattgtaaag agtcagcaaa aaaggcgcaa atgtaaaaac agtttctaca agtgttatac
      601 ctaaaaaaag ctagctgtgt aaaaaaaacg ctagcttttt tatttttttg tcttttattc
      661 acaatcttag atataaaagt gaatattatt aaaataagaa tcttgtagat attgggttct
      721 tatgcttgaa aaggaatgaa actacaaaca aacctttgtg aattcacaag cattaaactg
      781 ttgtatccgt tttatttctg ttatagtagt tttgtcgaag gacaaaatgt taatcggagg
      841 gaccataaat gaaagtagta gtaattggct gtactcatgc aggtactgca gctgtaaaaa
      901 gtattttaaa aaatcatcca gaagcagaag tgacagtata tgaaagaaat gacaatattt
      961 ctttcttatc ttgcggtatc gcactttatg tcggcggagt agtaaaggac ccagcaggct
     1021 tgttctactc aaatcctgaa gaattatctt cattaggagc aacagttaaa atggaacacg
     1081 atgtaacaga cgtcgataca gaaaataaaa cagtaacggc aaaagatctg aaaacaggag
     1141 aaacagaaac ggtttcttat gataaattag tgatgacaac tggttcatgg cctattatcc
     1201 caccgattag tggaatcgat gcgaaaaatg tactcctatg caaaaactac aatcaagcaa
     1261 atgaaattat tgcacaagcg aaagaagcaa aacgtgtagt aattgttggt ggtggatata
     1321 tcggtattga attagtagaa gcttttgtcg aatctggaaa acaagtgaca ttgattgatg
     1381 gattagatcg catcttgaat aaatatctag ataaaccatt cacagatatc ttagaaaaag
     1441 aattgacaga ccgcggtgtt actcttgcgc taggcgaaaa tgttactgaa tttatcacag
     1501 atgaagaagg aaaagtgaaa caagtagcta caccaacaga tacatttgat acagatatgg
     1561 tcattttatg tgtgggcttc cgtccaaata caaaactgat cgaaggaaaa gtagatacac
     1621 tgccaaacgg ggcaatcaaa gtgaatgaat acatgcagac aagtaatcca gacatttttg
     1681 cagctggaga ctctgcagta gtcaactaca atccaagtgg cacgcaaaac tatattcctt
     1741 tggcaacaaa tgccgttcgt caaggtttgc ttgtgggaaa taacttgaca gatcataaaa
     1801 tggcgtatcg tggtactcaa ggaacttcag gactttacct atttggctgg acgatcggtt
     1861 cgacaggtgt gaccaaagaa agcgcaactt tgaacgatct agaagtccaa gcgactgtat
     1921 ttgaagataa ttatcgtcca gagttcatgc caactactga aaaagtaatg atggagctag
     1981 tctatgaaaa aggaacgaat cgtatcgtag gtgctcagtt catgtccaaa tacgacatta
     2041 cacaatcagc aaataccatg tctttagctg ttcaaaataa aatgactgta gaagatctcg
     2101 cactttcaga tttcttcttc caaccacatt ttgaccgccc atggaattac ttgaacctac
     2161 ttgcacaagc agcgctaggc gaaatcgaaa ctgcacaata aagaaaaagg gttgtgacac
     2221 aattttgtca cgaccctctg tctttttttg tgaaaagtac aattagttgt ctttcttcga
     2281 attttttgtc acaataagca gcaaagataa agctgttaca taaaagaaca agcagcttta
     2341 tttgattttg aaaagaaagg tgagaaagaa gatgaataaa gaatattttg tccaacaaga
     2401 tgcattttta gaagattata aaagtgcttc gaagaaatta acgatcaata ttgatgagtt
     2461 ggcagatcaa gtactctctc agttgaatga aacgcaagag gaatattaca cgatgccagc
     2521 aaatgacgcc aaagataatg tttctcatcg ttttcctttc agtagacgca tctactcaga
     2581 tgaaaatgac ggcacattga atacagagta cacatatgaa ggtcagccat atgtgctaga
     2641 aactgatgat gatctttaaa gacagttttt gaaaaggccg ctcatcctta agtgatgaca
     2701 aaaaatcatc acaattaccg atgactgtct ctttactatc ttttaatcag aaaaaggggt
     2761 tatgacaagc tttgtcaacc ccttttt
//
LOCUS       DAYYEF010000131         2722 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000131 DAYYEF010000000
VERSION     DAYYEF010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2722
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.138"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(127..597)
                     /locus_tag="ACHA1B_002871"
     CDS             complement(127..597)
                     /locus_tag="ACHA1B_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703561.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            684..1382
                     /locus_tag="ACHA1B_002872"
     CDS             684..1382
                     /locus_tag="ACHA1B_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HFM8703562.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            1560..1901
                     /locus_tag="ACHA1B_002873"
     CDS             1560..1901
                     /locus_tag="ACHA1B_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703563.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            1894..2565
                     /locus_tag="ACHA1B_002874"
     CDS             1894..2565
                     /locus_tag="ACHA1B_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HFM8703564.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
BASE COUNT          998 a          396 c          552 g          776 t
ORIGIN      
        1 gtttacatgg tttggatttt tatggggctt gatgaagctg aagctgagta cagagcgaaa
       61 aagccaaccg agggggctga ctaaaaatga atagaaaaga gaaactagaa tgtatattac
      121 tattactcag tttaattctt tcactaattt ctctattggg aagtttgtat ttttgatatc
      181 aacaattttg tggatttggg ttctatttag agtaaatatc atttttgttt ggtgattaag
      241 gagtttatta aaattaattt tccctacttc aaatgcaagg taacaagata tagcactttt
      301 aggaggaata tttagcggta cagcttcaga gtatattcta ttatcatcga ctgatcctcc
      361 tttagcaatt aatttcttaa atggagtagc tgaccatctg cggtttaagt tagcggatga
      421 aagttctaaa ttaactaaca tagctggttc tgttgaatag ttagaaatga ttacttttgt
      481 ataaatcata tctgcagcga agtaagaagc attaagttca acttctagtt gagggcgcat
      541 tccttttatt tttatccctg ttaaaaacgt actcaatata aaacttatta ttgacatcca
      601 ttgaaaaatt gttaagtgaa aaaaattcaa aataaacacc accagttttt aactaaatta
      661 taccaaaaag gagagaagaa ataatgcaag aattagtaat tttgaaaaat aaagaagctg
      721 tgactacgag cttacaagtg gcagaaagct tcgagaaaaa acatcaacat gttttaagag
      781 atattgatgc actaaaaaaa gatgtgtcca attttggaca gatgtttgta gaaggtaatg
      841 aaccagattc atatggcaga aatcgacgag ttttcttcat tagtagagat ggatttttct
      901 tgctggctat ggggtttaca ggaaagaaag ctatctactt caaacaaaaa tacattgaag
      961 cattcaacga aatggaagat gttattcgca agaatactgt tcctcaaaca attgaagata
     1021 tgatgatcta tcaattagaa gaaatgaaag atgttaaaaa agatgtttcc atgcttaaag
     1081 atactatgcg aattagcgga caacaagagt ttgaaattaa gcaaaaagga aatatgaaag
     1141 ttatgggagt tctaggggga aaagaaagcc gagcttatga agaaatcagc aaaaaagtat
     1201 tctcaaaatt ttggtctgaa tttaaacgta ccttttcaat cccaagatat ggcgagttac
     1261 ctcgtaagag attcgatgat gctgtttcat ttattgaaat gtggttgcca gaaactgcga
     1321 tccgtatgga aattgatcaa ctgaacagac aacagagact ttttggtgat gacaatgaat
     1381 agagctgaag cgctaagaat agggacggca attgctaatt gctggtggaa atactataaa
     1441 ccaatcatcc taagccaaca acatattgac aagcaaaaag catggcaaca aataaaaaag
     1501 tgactccgcc ggcaagcaaa gagtcacaaa gaaaacacat cataaggaga ttttagcata
     1561 tggaaaaaga actttccact ctagatcaat atttgattga tcctgattgg ggcaagccga
     1621 aaattgagga aacaagtggt cgaaaaatca gacgaaatct tttgacgaat gaagaactag
     1681 cttgggatca agatgattta ggcaaccatg taactatttg ggatcatgtt tatcttatcc
     1741 atctatcgaa gcattcgaat aaacctgaat atatttacgt catcgaagat ggcttgattg
     1801 atgcgctaga agagtacgac agagataact tgattgatat ctcttattac ggaccaggta
     1861 agaaatacat tgctgaaatg gaggcagaat ttgatgagtg aaatcaaagg gacaacgaac
     1921 tttgaaaaac tttttagtcg taagttaaat aaaattctca agaaaaaagg aaattttgat
     1981 tatttatctt gggctcacgc gtgggagatt atgaaaaaga atgatccaca ggcaacggta
     2041 actattaatg agtacaaaca ctacagggtt gtttctggaa ctcatcaaga ctttcttgtt
     2101 gaggaatata aaccttttct tatggatgaa actgggactt atgtatctgt ctcagtaacg
     2161 gttaaaggac acacggaaac cgaattattt cctgttttag attatcgaaa ccaaccagtt
     2221 gttaaaccaa atgcaatgca aatcaataac tcattgaagc gatgctttgt gaaagcattg
     2281 gctctacacg gactgggatt atatgtattt caaggggaag atattccaac accacctaga
     2341 atcgatacaa agaaattaaa catgctagag acgattctag aagctttcaa tgagcagatg
     2401 ggtaaagata tgaccaaaac cttaatcgaa tatgttaatg agcagacaga taaattaggg
     2461 ctcttagctg ataacgttga aactattgaa cagttaagct atgagcaatg tgccttgatg
     2521 gagcgagcaa tagcagctaa gagaaaagaa ttagataaga agtgatatga gtgtttaaac
     2581 cattaatcga ttcatattca gcggttctga aaaagttcaa aggaaaagac ataagcgcaa
     2641 ccatcaatga ggaagtgaac attgatcgac taaagacgat gtatgacggc tacgatggtg
     2701 atcgagtcat tgaaattcgt tt
//
LOCUS       DAYYEF010000132         2490 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000132 DAYYEF010000000
VERSION     DAYYEF010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.139"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(365..1657)
                     /locus_tag="ACHA1B_002875"
     CDS             complement(365..1657)
                     /locus_tag="ACHA1B_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFM8703565.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(1931..2191)
                     /locus_tag="ACHA1B_002876"
     CDS             complement(1931..2191)
                     /locus_tag="ACHA1B_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703566.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          844 a          465 c          381 g          800 t
ORIGIN      
        1 tatgggctac tctgtgatac ttattagcca ttaaactatt ttacccacat agcatatatt
       61 ttgaaatcgt tcattccgta aattcaacta aatatgccta aaaaaataaa aaatctaaga
      121 tagaataaga tttattcagt cttagatgga tttatagcaa ctttttcgta acaactttaa
      181 aaaatacgaa aagaaagagc tgttttactc tgactacgtt gctaaattgt cgtttaatca
      241 ttcatttaaa ccaaatcttt ttttatagaa ttcgttttaa tcctcctgaa tccaaaaact
      301 atgaaaaccg taattaaata gttaagagtt tttaaccacc ataattctct cggctatttt
      361 gaaatcagat aaattttgat cggacacata gttgaataaa cctaccgttg ttacggaagg
      421 taaatcgcat acttttcatt ctagaggaga aggtctcgtt gatcattaac tgattaagca
      481 ccatagccca gttttgaatt cgaccacctg accacttcgc gtgtaattct ttcgtgcgta
      541 aataaagtag ttttaggagt gcattctcat tagagaacgc tccttttttt gtgacttttc
      601 tgaagctgga gtggacactt tcaaccgcat tggtagtgta cataattttt cgaatggcac
      661 taccataatc aaatagttgt tcaacatgtg caaagttccg tttccagaca tctacagcac
      721 cagaataatg agaccaccga ttttgaaaac tgtcaaaagc agcatgtgca gcgtttagag
      781 aagaagcacc gtagaacttt ttcatatctc ggcagacttc cttatagtcc ttacttggaa
      841 tatagcgcaa tgcatttcga acaagatgaa caatacagcg ctgaacaatt accgatggaa
      901 agatcgcttt tgcgccttct tcgaggccag aaacaccgtc catcgaaatg aaaaagacat
      961 cttcgacacc acgtgctttc agttcatcaa atacttgcat ccagcgattt ttagattctg
     1021 tttgatttaa ccataatcct aaaatctcct tatttccttt gagatcatag ccaagaatgg
     1081 tgtatacagc atattctttg gcttcataat tttctcgtaa agtaacatac atacaatcaa
     1141 cgaatagaaa ggcataacac tttgctaggg ggcgggcttg ccattcttcc aattcaggaa
     1201 ggacagcgtc agtgatatct gaaatcattt catgggaaat atcaaagcca taaatagctt
     1261 cgacggttgc ggcaatatct cgttgactca ttcctcgtgc atacatggaa agaaccttcc
     1321 cttcgatgtc ggagacatct cgttttctct taggaattaa ctctggttca aaggaagctt
     1381 cccggtctct aggaacatca atagctactt caccaaaact ggttttaagc gttttagttc
     1441 catagccatt tcgacggtta tcgtgttcct taggctcttt agaatgggca tcataaccta
     1501 aatgattatt caattctcct tgaagcattt tttcaaaaag gggcccaaac acatctttca
     1561 aagcatcttg catgtcatcg acagattcag gttgataggc attcagaatg gattcagcta
     1621 acttttcggc atcaggattt cttttctttc tagccatcgt gtaatcacct cttgatctta
     1681 ttgtagaaaa agaaaaaccg cgaagcaacc acctgcctag gattaatggt tacttacacg
     1741 gtttatatta cactctcatc attaaaaaag tatctttcga tattactaaa caatgaaatt
     1801 atctatttga aatttaaatc tgataatata ttgagtgttc caatgagggc tttgatccta
     1861 ttatccatat ctttttcagt tttaatattg atacacatta taagaaaaag aaacttttgg
     1921 ttaatttatt tcatcccagt gcaaaatata aaaaagtaaa atagaccata ggcaatagat
     1981 taacaattaa tataatacaa gcaaatattc tattcattgt atttctgctt tcaaaaagtt
     2041 ctaatattga aagtataatt ccacaaatgc ctataataag tatgggaata agattagaaa
     2101 ataacacccc gagccaatct gtgaaaatta ctatatttac taatatccct attaacatac
     2161 ctatcatatt tattaaatca atttttttca ttagatattt ctcctttatt aaatctgaag
     2221 tacttatatt aaaataattc taaactattt acctcaaaaa gtgcaataaa ttatttctga
     2281 acaataaaat gatagtcaaa acaaaaaaat attgttaatc gttcagagcc atccgagagt
     2341 gtaaaatatt ttgtgtaaat gaaaaaatcc atacaaaaaa ggaaggcgct tctgtagaat
     2401 aaagttaacg acaaccaatt cacagaaaag aggacttccc tatgaatgat tttactacag
     2461 aaattgtgca aactctagtc actaaaggcg
//
LOCUS       DAYYEF010000133         2398 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000133 DAYYEF010000000
VERSION     DAYYEF010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.140"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            207..2069
                     /locus_tag="ACHA1B_002877"
     CDS             207..2069
                     /locus_tag="ACHA1B_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HFM8703567.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLIILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="ACHA1B_002878"
     CDS             2069..>2398
                     /locus_tag="ACHA1B_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFM8703568.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          465 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt atcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAYYEF010000134         2262 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000134 DAYYEF010000000
VERSION     DAYYEF010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.141"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(151..>2262)
                     /locus_tag="ACHA1B_002879"
     CDS             complement(151..>2262)
                     /locus_tag="ACHA1B_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008658 - penicillin binding [Evidence
                     IEA];
                     GO_process: GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan D,D-transpeptidase FtsI family
                     protein"
                     /protein_id="HFM8703569.1"
                     /translation="LEKIRKGAQEPKNKTFRRSHVPFRLNFLFFIIFTLFVALIARLG
                     YLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKANQAITYTRGTQVTA
                     KDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKRLSAKEKQLGNSEQY
                     SAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGVTDQELAVVAERASE
                     LPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLAKGYSRNDRVGQSYL
                     EKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSMNAEFQSKVEEILKR
                     NYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEITENALGTITSAFDP
                     GSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRSGQVALDAVKASELS
                     SNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFGLGTTTGIDLPNESP
                     GISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQYASTVANGGKRVQP
                     HLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGFHQVVHGTDPYTTAK
                     PLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEIAISVVLPNLLDEQD
                     HINLTIAKEIMDAYYDMFMAK"
BASE COUNT          576 a          505 c          411 g          770 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aa
//
LOCUS       DAYYEF010000135         2254 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000135 DAYYEF010000000
VERSION     DAYYEF010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.142"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(256..1104)
                     /locus_tag="ACHA1B_002880"
     CDS             complement(256..1104)
                     /locus_tag="ACHA1B_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HFM8703570.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(1328..>2254)
                     /gene="thrS"
                     /locus_tag="ACHA1B_002881"
     CDS             complement(1328..>2254)
                     /gene="thrS"
                     /locus_tag="ACHA1B_002881"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA];
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HFM8703571.1"
                     /translation="MMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTL
                     NDGHTFVRPDQIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWE
                     KAQAMLKAAMDELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERF
                     DLTYVGEDGENTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVD
                     AHGDYAYEIKERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVN
                     VRRYGSKETAVEDLNIFIDAMEAEVKNYSREN"
BASE COUNT          652 a          462 c          359 g          781 t
ORIGIN      
        1 tacccaaaaa cttcttaata aaaaagaaaa aatgggcgga gcaagaaatt ctttacctaa
       61 tttcaagata aaatcaactt tttgtttcac agcaatcact taaagttaca tatccaacta
      121 tttttttcat taaaaaataa acttattttt gaaaattatg ttttcttaag tcgtgaaaca
      181 ctttgatgga tcatttattt gtggaaaact acgttttgtt attctaaaaa acttatataa
      241 aaaatagtaa ggtttttatt tcgaatccat aaaatattct tggattgctt ctcgtgtttt
      301 tttcactttt tcgctaagct tttcgttttt agccatatag aaataaaaaa tgatatcgat
      361 cgtagcaaat tgggccaaaa gtgaattagt tgccgcactt cgattcgtga tttcttttgg
      421 tctagatgtt tgtacgagta catcggctat cttgctaagc gggttatttc caaattgcgt
      481 caacgcaatg atttcgatat tcatgctttt cgccagctcg gctaatgcga ctacatctgc
      541 acttctacct gagtttgaaa caagccaaag cactttcttt ttctcattgc tgacaagttg
      601 cgggagcaag acgtggatat ctttttcaaa aatgattggc ttaccgacac gagaccattt
      661 ttgcagaata tcttctacta ctaaagaaga ggcgccaacc ccatataaaa aaacagtctc
      721 tgccgattcc aaacactcta cgactttttg gatcgtttct tcttctagaa tatctactgt
      781 ttcttttatc gctacttgtg cattgttacc aagtttgttt ttgatagagt aaaaggactc
      841 atttgcttct atatcactaa aaccttcatc gattccagtc tgtagttctg ttgaaatcgt
      901 gattttgaag tccgtcagac tttgaaaacc gatttttttg gaaaaacgta caactgtcgg
      961 cgcactcaac ccggaagctt ctgctaattc attagctgtc attgtaggga ccttctcaat
     1021 attaccgata atgtagttgg ccaacttttt ttctgctgaa gaataatctt ccatcatact
     1081 ttcaatacga ctaattacgc tcataagttc ctccaccctt ttaatgatag tctatgtaag
     1141 tataccatat cagaccctta ttcacggtcg tatactggat aaaaaacaaa aaaacaatcc
     1201 gcccaacaga atatcttatc ccatcaatcc cacagattct attgagcatc tgtgtctttg
     1261 aggaatacct gttatctatt gttcggattg ctttctatct actacttttt tacaggaaat
     1321 ttacctatta gttttctctg ctgtaatttt tgacttctgc ttccatagca tcaataaaga
     1381 tattcaaatc ttctacagct gtttctttac ttccataacg acgtacgttc actgttgcat
     1441 cttccaattc cttgtctcca acaactaatt ggtaagggat cttttgtgtt tgagaggcac
     1501 gtatcttata gcccattttt tcattacgat catcaacttc tacacgcaac cccttcattt
     1561 gcaaacgttc tttgatttca taagcataat cgccatgtgc atcaacagaa acagggatga
     1621 ttgttgcttg tataggtgcc aaccatgttg gaaaagcgcc tttgtatact tctgttaaat
     1681 aagcgacaaa acgttccatt gtagaaacaa ttccgcggtg gataactact ggacgatgcg
     1741 tattttcccc gtcttctcca acatatgtca aatcaaagcg ctctggcaat aagaagtcta
     1801 attgtatagt tgataatgtt tcttctgtac caagagctgt tttgacttga acatctagtt
     1861 ttggtccgta aaaggctgcc tcgccttctg cttcaaagta atctagttct aattcatcca
     1921 tagcggcttt cagcattgct tgggcttttt cccacattgc gtcatcatca aaatatttat
     1981 ctgtattgtt tggatcgcga tagctcaagc ggaaacgata atctgtaata ttgaagtcag
     2041 catatactgc caccatcaat tcaagcgtac gtttaaattc atctttgatt tgatcaggac
     2101 gaacaaatgt atgaccatca ttcaacgtca tttctcgtac acgttgtaaa cctgacaaag
     2161 cacctgattt ttcatagcga tgcatcattc ctaattcagc gatacgaatt ggtaattcac
     2221 gataagaatg gatcgtgttt ttgtagacca tcat
//
LOCUS       DAYYEF010000136         2214 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000136 DAYYEF010000000
VERSION     DAYYEF010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2214
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.143"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(48..1391)
                     /locus_tag="ACHA1B_002882"
     CDS             complement(48..1391)
                     /locus_tag="ACHA1B_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HFM8703572.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFLETAVDKIDIQNKKIICVKKDGTRFSQ
                     EYDKLILATGSKQIMLDVPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGKKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHIDNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPVFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            complement(1525..>2214)
                     /locus_tag="ACHA1B_002883"
     CDS             complement(1525..>2214)
                     /locus_tag="ACHA1B_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rib/alpha-like domain-containing protein"
                     /protein_id="HFM8703573.1"
                     /translation="NPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTA
                     GNKKGIVVVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTV
                     TLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEKDSE
                     KAVSKDNKTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGTLGL
                     LGYKNRKKENE"
BASE COUNT          664 a          401 c          277 g          872 t
ORIGIN      
        1 aatgaattga gtaatacagt atatttcttg atttcattta gtaacgatta tgtttcaatg
       61 tttaatcctg ttactgcctt taaaataaaa ttatagggtt ggctaaaact aggatgaaat
      121 aaataatcta acattttcaa tttgtctaat gtaatttgtt cttctatagc aagagaaaac
      181 attgataata gtccagataa atcttcttga ctacaaagtt gtacacctac tattctcttt
      241 gtattttttt caaagctaat tcttaatttt acacgactat tttttctcaa aaaaacaggt
      301 ctaatgaaat cttctatttc tatataatct atagactcac ttaataatcg tgctgttttt
      361 aaattcaaac ctgctgcgta aaaattgtaa ttaaatatag aaaagccatt tgtaaattgg
      421 gaaccagaag gtgtaaaatc ttgattgtca atatgttgag ttgcaatata agctgttctt
      481 agagcattag aaatagaaaa atcaacacta cttctattaa tggacgtaaa aaaagttgta
      541 gcacaatccc caatagcata tatatctttt atatttgttt gctggtattc attagttaga
      601 tatgctccac taacatctct caagagttcc tttttgccaa ttggactatt agatagaaat
      661 cctatagctt gtacgaccat atccatagag tattgggtac cacttgtagt gactattttt
      721 tcaatctttt ttcttcctaa atatttttta ggactttctg atagacaaag atgtattcca
      781 ttttttgata gtatttcttc aactttatct gaaaaactac ggtcgtaata agtcgacaac
      841 actctatctg caacatcgaa aagatatact tctttccctc tttttcttat ggcttcagca
      901 atttcaactc caatatatcc tgctccaata attcctactt ttttaatagt attatcatct
      961 aaagctttaa aaatctcttt agcatttgga aaattcttta tcgaaaaaat attagctaaa
     1021 ttattccccg gtacatctaa cataatttgc tttgaacctg tagctagtat aagtttgtca
     1081 tattcttggg aaaatcttgt gccatctttt tttacacaaa taatcttttt attttgaata
     1141 tcaattttgt caactgctgt ctccaaaaac aactttttta tcttagaatt tagttctctt
     1201 ctattttgat aaaaaagatc ttctaaattg ctaacttctc tttttatgaa caacgatgtc
     1261 ccacattcta agtaactaat ttctgatttt ttatctatca gaataacttc ataatttgaa
     1321 tcacataagt ttagaaatcg agctgcagct agccccgaat ggtttgatcc aataattact
     1381 atttttttca cttaatcaca ttcttttccc ttctatgaaa agtatcttca tttttaacta
     1441 acaacctatc tcccaaaata aaaaacaaaa agaggaagaa aaagattctt cctcttttca
     1501 gagaagattt aagaaattga ttttctattc attctctttt tttcgatttt tataccctaa
     1561 taaccctaaa gttcctaaca ggattaaacc accactaata gtaaagatat tactatcaat
     1621 ctctcccgtc ttaggataag cttttgagga ctgcttttga ggactgcttt tgcctctatt
     1681 tttgttttgc ttgctacctt gattgtcagt cttattatct ttactaacgg ctttttcact
     1741 gtctttttcg tttgaagaaa caactacatt agtaggttca ctagtattac cagattcatc
     1801 agttgcagtt actatcactt ttgttcctgc ctctaattta ggaactttaa ctgtaaaatt
     1861 accattttta tcagctgtcc catggtattg actcccgttt ggtaatgtaa ctgtcacctc
     1921 tgcatttggt tcagttttac cagtaacaat ttggtcaccc tctgtaatag gatcaacttg
     1981 aggtttattc ggtgcttttt tatcttctac agaaatagta acctctactt cttctttaga
     2041 tccatctgga tatgttacta ctacaatccc ttttttgttt ccagctgtac taacatctac
     2101 tttctctttc caagtataag tagttccttt tggtagatct tctttgttct taattccctc
     2161 agatgcgtct ggctctttat ttaagtctgt agtcactttt tgtccttcag gatt
//
LOCUS       DAYYEF010000137         2139 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000137 DAYYEF010000000
VERSION     DAYYEF010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.144"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(103..1029)
                     /gene="cysK"
                     /locus_tag="ACHA1B_002884"
     CDS             complement(103..1029)
                     /gene="cysK"
                     /locus_tag="ACHA1B_002884"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004124 - cysteine synthase activity
                     [Evidence IEA];
                     GO_process: GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HFM8703574.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            complement(1169..2056)
                     /locus_tag="ACHA1B_002885"
     CDS             complement(1169..2056)
                     /locus_tag="ACHA1B_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004040 - amidase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HFM8703575.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
BASE COUNT          591 a          478 c          357 g          713 t
ORIGIN      
        1 tacgtctcta ttcaaataat ttttctcatc ataaattttt gtgtgttctt ttcatcttta
       61 aaagtttttt acataaacct atctggagaa aaaccaagtg ccttatatct cttggtaaag
      121 ggctgtagat aaataacgtt caccattgtc gggaaccaca gctaatacct tcttgccttt
      181 tcctaattct tttgcgactt ttagcgcggc agcaattgca gcgccagatg agatgcctac
      241 taaaatccct tcttttcgcc caacttctct agctgtttcc atcgcttcgt ctccactaat
      301 agaaaggact ttatcataca cagaagtatc cagtgtttta ggaacaaaac ctgtaccgat
      361 tccttggatt ttgtgaggtc ccgcttcttt cccttctaaa atagcagatt ctgctggttc
      421 taccccgatt aattcgattt tcggatacac acgttttaat tctcggccag cgccagtgat
      481 cgttcctcct gtaccgatac ctgcaacaaa cgcgtccaag ccatttactc caaatgcttg
      541 atgtatctca ggaccagtcg tcttctcatg cacaagagga tttgcttcat tttcaaattg
      601 taatggtaaa aagtagccgt tttcttttgc caaacgttct gcttctctga ttgatccaga
      661 aataccatcc gcaccaggag tcaaaatcaa ctctgcgccg taccctttca tcaataaacg
      721 tctttcgata ctcatcgtct caggcatcac gatgattact ttatatcctt ttgcaactcc
      781 taccatcgac aatccgattc ctgtatttcc agaagtaggt tcaatgatag tatcacctgg
      841 tttcagtaga ccatcgtgtt ctgctttttc tatcatactt aaagcaatac gatcttttac
      901 acttcctcct ggattaaaaa actcaagctt tacaaaaaca tctgctgaat cttctggtac
      961 gattttattt aatttgacga ttggcgtttt gccaatcaat tcggtgactg agttatagat
     1021 agctgtcatc ttcaattcct ccttgtcttt gctcttctta cttatcataa tacaatctgt
     1081 tcatttatgg cgagtgattc gtctttgact agcaaaaaaa agacaaagat ataccatata
     1141 tggtaatttc tttgcctttt tatctaaatc aaacgtttag ttcttgacca actaataaag
     1201 aataactgga catagacatg ccatttttcg ccattagatc atcaacagac atgccaaatt
     1261 tttgtgcaat atcccatagc gtatcacctg acacgactgt atatgtctga ccattatttg
     1321 tatttacatc tgttgttgaa gatgatgacg ttgaagtcgt cgtagtagtc gttgttgttg
     1381 tacttgtggt tgttgtagcc gaacctgttg atggcgtatc aaaacgggtt aaattataag
     1441 tattaatcaa tgagttcaat ttggccccat aatttggatc ggtagcataa cgacctgtca
     1501 agtacgctgt tgcatcataa aaacttgttg tattgctttt ccacacgcca gcataatgat
     1561 aatcgcccgt ggaaaaactg gttgaacgaa gaacattcgc atggtcttgg aaggattccc
     1621 aataagaaga atattttcgg aatggctcat tcatcgttac ccattgtccg tttacatatt
     1681 ctttggttgc catataaacg acctgtccgt tatagcttcc tttcacaccg aatagattat
     1741 aatttggcgc actagctaat ccggaagtgc catatgcact ttccaacaac gcttgagcga
     1801 tcatgactga agcatacaag tcattacttg cagcaacttc tgacgcagac cagccgattt
     1861 gatcgataaa cgcttgagga tcagcgactg tttgagatcc ttgttcatct gcatgaacat
     1921 gttgcggtac cgctgtaacc atcatcggcc caactaaaag actcgttcca attaaaggag
     1981 caatcgcttt tttattgatc accatttttc ttttaggtct atggtgccgg gcactgcggg
     2041 tcttcagctc ttgcattcaa attcctcctc aaaataaaaa aacttaataa aaagttctct
     2101 tcttaaaaca aacttaatta attaaattat acttttaat
//
LOCUS       DAYYEF010000138         2136 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000138 DAYYEF010000000
VERSION     DAYYEF010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.145"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            24..635
                     /locus_tag="ACHA1B_002886"
     CDS             24..635
                     /locus_tag="ACHA1B_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HFM8703576.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            620..2011
                     /locus_tag="ACHA1B_002887"
     CDS             620..2011
                     /locus_tag="ACHA1B_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HFM8703577.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
BASE COUNT          822 a          303 c          404 g          607 t
ORIGIN      
        1 aaaaaaatgt gaggggataa tcaatggatg ataaacaaaa aatgtacgaa aaaaatcgca
       61 aacatagtga ggccttaaat tttcgtgtcg ataaaaagac ttatcttgaa ctgacattga
      121 ttgcaaaaca aaggggaatt tctagagcag acgtttgccg tgagcggtta aagggactca
      181 aatatgaacc gccgttgtta gctgaagatg atagggtagt tttaaccaaa cagttaaatc
      241 aaattggtaa caatttgaat caagcggtaa aggcattaaa tatcattgct aaatatttta
      301 gagaagaatc tgaagataaa aaagaaaaga gcctacattt tagttttgat gctagccgtt
      361 acaacatttt taaagatgaa cttgcgaata gcatagcaaa aaagttgatg attagttatc
      421 cagatgacat ttttttggag tccaatcgga gtgccccctc tttttttaaa ttatcagaag
      481 tagaaaaaga atatttcgaa tattggatag aaaagcaaac tagaccgggt acgaaagaag
      541 agtattccca aaaagttgat cggaatttaa ttcactcaat tcagattatt gcaagtttaa
      601 aagatgaggt gaaacaactt tgggagctac tataacatcg aaaggacgca agaaaaattt
      661 atcctcgcta ttacaatatg cagctaatcc ttcaaaaaaa gaaaaatgtg ttgcagtctc
      721 aggaataaat tgtagtgatg atagtgagga agcactgcaa gaaatgaatt tagtacgtac
      781 caagatgaat aaatctaaag atatagcaca agcgtttcat gttattcatt cgtttgataa
      841 gagtacttct aaagagttaa gtattgataa aatgcacgaa atagctgtcg aatttgcaga
      901 gaaagctttt ccaaattcgc aaatcattgt tgcaagtcac aatgataaag atcattttca
      961 tagtcatctt gtcattaata atattaacat ggaaacatgt aaaaggttgc gtattgaccc
     1021 taaagattta gaactaatgc gaaaaattaa cgatcaagtc ctcaatgaac atggtcttga
     1081 atcagtgaat aatgagtact atgaaaactt agaaaagaga accaatcttt attcaaacga
     1141 tccttctaag atgaaatatg gaaaaattaa ttatcaagag tttgtgcaaa atgcgatcga
     1201 agcaacgttg gaaaaatgcg aagtgaattc ttttgaagat ttttcggatc atttggcaaa
     1261 agaatataac attgaagttt atcaattttc aaaaacaaat aacaaacttg gctatgttct
     1321 ttacaaacaa ggtgtaaatt tctatgagcg tagaggtgag ttaattactt taggaagaga
     1381 taaacaatct agaaaagaaa aaagtcagta tgtcgaacgt acttttagtg caagaaagtt
     1441 agggaaaaga tattcatttg aatctgtttc tgaacaactt gaaaagaatt tagaagaatc
     1501 acatataaaa aattttttta atatggaaag agagcaagtt atgtcgctaa ttagtggagt
     1561 aaattacaaa actggtgagt taaatgtacc ttttgtggaa ttagattcca tcgcacaaaa
     1621 gcaatttagc gaccgtgaag gcgatgaaaa attcattaaa tatgatgact tcttgcgaga
     1681 ggtagacaag cattttgtaa acacaatgtc tttagaagat gatcaagaat acacgattaa
     1741 acttcatacg gatgtgaatc ctcaaacttt acgtagtgcg aaaagtaaaa caatttctat
     1801 taaaaagact gatcagaaag agttatttct accggcaaag ggttttgaaa attgttctca
     1861 tacaccttct gctaaacaga ttcactatca aatcagtcgc ataatgaatg acgatgtaaa
     1921 aatgtatcgt gctaaaaagg attatgaatt cacacaacaa atgattgaaa atcagcaaaa
     1981 aaggcaacaa aattttgaaa tggaattctg aatgggcttg ttagtggact ttccagtttt
     2041 ttgcctatga agagttgctt ggaaagaagc agtttttagg acatacgcca gctacccatc
     2101 tacttgccag tcaatccgcc ccgctcacgc taggct
//
LOCUS       DAYYEF010000139         2056 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000139 DAYYEF010000000
VERSION     DAYYEF010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.146"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            493..714
                     /locus_tag="ACHA1B_002888"
     CDS             493..714
                     /locus_tag="ACHA1B_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703578.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="ACHA1B_002889"
     CDS             715..972
                     /locus_tag="ACHA1B_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703579.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKVAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="ACHA1B_002890"
     CDS             complement(1108..1710)
                     /locus_tag="ACHA1B_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HFM8703580.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKLRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="ACHA1B_002891"
     CDS             complement(1777..1932)
                     /locus_tag="ACHA1B_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0032993 - protein-DNA complex [Evidence
                     IEA];
                     GO_process: GO:0006276 - plasmid maintenance [Evidence
                     IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HFM8703581.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          462 c          314 g          602 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggtggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaag cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatta ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DAYYEF010000140         2010 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000140 DAYYEF010000000
VERSION     DAYYEF010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2010
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.147"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            100..1278
                     /locus_tag="ACHA1B_002892"
                     /pseudo
     CDS             100..1278
                     /locus_tag="ACHA1B_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
     gene            1455..1741
                     /locus_tag="ACHA1B_002893"
                     /pseudo
     CDS             1455..1741
                     /locus_tag="ACHA1B_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          691 a          374 c          337 g          608 t
ORIGIN      
        1 ttgacgagag tgtaaaatat tttgtgtaaa tagaaaaaag gaagtccctt ctgtagaata
       61 gagttaccac aacacattca cagaaaagag gacttccata tgaacgattt tactacagaa
      121 attctaaaga ctctagcgaa caaaggcgat ttgaatgaat tattccgtgt ccatttggaa
      181 aaagctgtca atacgcttct caaaacggag ttaacggctt tcctcgatta cgaaaagtac
      241 gatcgcattg gttttaacac ggggaattct cgtaacggct cctatgaccg tacggtcaag
      301 accgagtacg gggaacttca tctccagatt ccgcgcgacc gcaacggcga gttcaagcaa
      361 cagactgttc ctgcttatag acggacgaat gatatcttag aggagaccgt cattcacctc
      421 ttccgaaaag gtattaccat gtcggaaatc gcagacttga ttgagaaaat gtatgggcat
      481 cactacacgc cccaaaccat gtccaacatg actaaagtgc tgactgaaga agtaaatgca
      541 tttaaagtta gaactctaaa tgataagtat gtcgctattt tcatggatgc tacttatatt
      601 cctttaaaac ggcaaaccgt ctccaaagaa gcaatctata ttgccattgg tatacgagaa
      661 gacggcacta aagaagtact aagttatgcg attgctccga ctgaatcgac ctacgtttgg
      721 aatgagttgt tacaggacat ttactccaga ggggttcatg atgtcttact gtttattacc
      781 gatggcttaa aaggcatgaa agatacgatt caccagattt atcctaaagc taaataccaa
      841 cattgctgtg ttcacgtttc ccgtaatatt gctcataaag tacgtgtcaa agatcgaaaa
      901 gaaatctgtg atgattttaa ggctgtttat caagctagct caaaggaaga ggcaaatacc
      961 tttttaggga gtatgattga gaagtagcaa aaaacttatc ctaaagtgac gcagtcactg
     1021 ataaaaaatc aagatttatt gactttttat gagtttccgc ctggtatccg ccgaagcatt
     1081 tactcaacta atttaatcga atctttcaag aaacaaatca agaaatacag ccgcagaaaa
     1141 gagcagtttc aaaatgaaga atcactagag cgtttcctag tatccatctt tgatacatac
     1201 aatcaaaaat tcttaaatag aagccataaa ggcttccaac aagtgacgga tacattagct
     1261 tcaatgttta ctgagtaacc cattattttg cagaaggacg agttatttac acaaaattat
     1321 tgacgctccc tccaaattac ttcatcaaaa cattgatata atttttatta tatcagtatt
     1381 tattcttgat acataaatga gaaaataaat actttaaatc tattgactac aagtagtcat
     1441 taagtcttca taagatgtac aatatgacat taaaaaaata aaagcttacg accatccgtt
     1501 aaatctgaca ctaaataatg gactgctttc ttttgtatta gcaggttacg ttgactatga
     1561 atattcacca gattatttgg agaaacctct tcaacacgag aacaatgata ttaattttag
     1621 atttgtctac gagtcaaaaa gtaaaacatg gttagttgat caattaagca cgataaacac
     1681 aagcttccat gaattaccta aacctgaaaa tgaagttgag atggtcatta aaatcttcta
     1741 aaaaagaagc gttgaagggg aaatattcct ttcaacgctc ttttttatat gcttagaaac
     1801 ataaataaat tgtatacttt ctttttagcc cctattactt ttcacgaaaa atatcttttt
     1861 ttcgacgcta gcgtttctct acttctaata ctgtacacag tttttgtatt attgaaaaat
     1921 tactcattat ttagcattaa tccacatcgt tttatcaatc gaccttcata ctaaactact
     1981 ttaaagtcat cttccttctc gtttttcatt
//
LOCUS       DAYYEF010000141         2001 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000141 DAYYEF010000000
VERSION     DAYYEF010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.148"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..376
                     /locus_tag="ACHA1B_002894"
     CDS             <1..376
                     /locus_tag="ACHA1B_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HFM8703582.1"
                     /translation="NVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFRR
                     FPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTDD
                     WQKVMAAEVIATYLDGDLVYKK"
     gene            424..1824
                     /locus_tag="ACHA1B_002895"
     CDS             424..1824
                     /locus_tag="ACHA1B_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HFM8703583.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
BASE COUNT          553 a          339 c          432 g          677 t
ORIGIN      
        1 aaatgtttcc acagaggact tctttaatta ttgtcgatta gaggaaagtg gtgtaacagt
       61 cactagcggt acagatttac cgctgtttat tactgatatt cctgaatcga ttataagagc
      121 agtattccgt cgttttcctg aaggagaaga agtctgggag aaagaaacaa gcttcacgac
      181 aaccgagctg ctgaaaagtt ttacaagcaa cagcttcaaa gtaaatggtt tatcggagta
      241 cggagaaata aaagtaggga aaagcgccag cttagctgtt ttcagcgagg acctctgtac
      301 tgatgactgg caaaaagtga tggctgcgga agttatcgct acctatcttg atggtgactt
      361 agtttacaag aaataatgct tttcgatata acgttataaa acgaattaaa gagaggttaa
      421 aaaatggaaa caatgaaaag aaaattcacc ttcccacata gttatacatt gatttttatc
      481 ttaattattt tggctgcaat tttaacttgg ataattccta gtggtcagtt tgagacagtt
      541 gttgaaaacg tcgcaggtat ggaaaaaaca acggttgttc cgggaaccta tcaccaaatc
      601 gataaggcag attatggaca aggtttttcc tctatactaa tggcaccagc tgaagggatt
      661 atttcagctg ttgaggttgt tgcttttgtt ctcatcgttg gtggtgcctt cgggattatc
      721 ctaaaaacgg gagccatcga tcgagggctg tttaccttag caaaagttct gggagacaag
      781 gggatcttag ttattccgat gtcgatgatt ctattcagct taggaggatc aacctttggc
      841 atgagcgagg aagtcattcc cttatttgcg gtgtttattt ctctgatgtt ttctcttggc
      901 tatgattcca tgactgcgat cttgattcta tttttaagta cacaagcggg atatgttggg
      961 tcgacgatta atcccttcaa cgttttaatc gcacagggag tagctggcgt ttacggaaat
     1021 cccctgcttt ggtttcggat gctatcctgg attgtcatta ctgggatttc aattgttttc
     1081 accatgcttt atgctagcag agtcaaaaag aatccactgt cctctattgt ttatgagagt
     1141 gatttaaagg ttaagcataa gtttcaaaat tttgacactg aaaaagagtt ttcaacacaa
     1201 gataaactaa ttatcgccgg ttttatcgta ggtttaggaa tcatgatttg gggtatcatt
     1261 tccaagggat ggtatatggt tgaaatttct gcactattct taggattagg tctttttgct
     1321 gggggcatcg ctagattttc tcaaaaggaa attgctgaag cttttgtcga aggctgttca
     1381 gatttcgcct atgctgctgt aatcattggg ctagctagag gagtcttggt aatcttggaa
     1441 ggtggaatga ttattgacac tattctaaac agcttggcta accttttagg tggtcttcca
     1501 aaattcctgt tcactacgat tctactcatt tctcaagtaa ttgtttcctt ttttgttcca
     1561 tcctcctcag gagctgcggc attaacgatg ccggttatgg caccattggg tgatctaatg
     1621 aatgtaagtc gtgatgttgt tgttctaagt aaccagtttg gaaatggttt aatgaatatt
     1681 atctccccaa ctagtggtgt attactggca ggattagcca tcgcagagat taatttctct
     1741 aaatggttta aggttggctt caaaatattt gccatcttaa cccttgtttc tgctgttttg
     1801 ttatacattg ctacactctt ttagtcttaa tcatccatta ataggaggca atagttatga
     1861 ttaaaataaa tcaattagca ggaatgaata tccactattt attttattct ctcaaagaat
     1921 ttttcgctta tcaacagaaa attggtattt cttctgttga actttgggga ggtgctccgc
     1981 attttttcat agatgctttt a
//
LOCUS       DAYYEF010000142         1989 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000142 DAYYEF010000000
VERSION     DAYYEF010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.149"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            270..836
                     /gene="amaP"
                     /locus_tag="ACHA1B_002896"
     CDS             270..836
                     /gene="amaP"
                     /locus_tag="ACHA1B_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HFM8703584.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            849..1037
                     /locus_tag="ACHA1B_002897"
     CDS             849..1037
                     /locus_tag="ACHA1B_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HFM8703585.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1050..1607
                     /locus_tag="ACHA1B_002898"
     CDS             1050..1607
                     /locus_tag="ACHA1B_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HFM8703586.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1639..1881
                     /locus_tag="ACHA1B_002899"
     CDS             1639..1881
                     /locus_tag="ACHA1B_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HFM8703587.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          722 a          308 c          406 g          553 t
ORIGIN      
        1 aaatagaatc ttgtaataat aactgagcat aatctttgca atttttaatc ttgaataata
       61 tcctttaagt atagccagca atcaaaagta aatagagaat aagtaagcaa ttgttatttc
      121 agtatcagac tggcaataaa acgccgttat gatccagcaa tgtttggtag cgctttattt
      181 actgatgcta tgctaactgt tcgctatcta tactgtgatt gtcggtagag ttatttacag
      241 ggtaaaaata agtttatagg aggtggaaaa tgaataaggg gttaaaaata atcggtgtta
      301 tcatgagttt actgctactt tcagtatttc tagcgattgc gttgatcaat gcgccgtata
      361 ttatgcctga acaattggaa cgatttcgct tctttacttt aacgaattac tacatgcaac
      421 aatatatttt ctgggcagct gtagtatttg ccgttcttgc tattatcatc ttgctagtcg
      481 ttcttttcta tccaaagtca agaggaactt tcgttatgaa acgggaagat ggcaaactaa
      541 caatcgacaa aaaagcgatc gaagggttgg tacgttccca tttacacgaa gaagagttca
      601 ttcattcacc taaagtacgg atacgttcaa cgaaaaatcg aatccatatc catgtcaacg
      661 gagacttgaa acgaacttct tcattagtag ggaaaacagg tgtattgatg caagatatcg
      721 aagaagaagt aactaaagta ctcggaacaa aagaaacggt caaagtggca gtcacataca
      781 gcggttatga agaacaagaa gatacaagag actacaagca ctctcgagtg gaataggagg
      841 gccaaataat gaaagaacta ttttcagcat acaagctccc tattatcttt gggggtcttg
      901 gactactgct agctgtttta tggttaacga ttggattttt caagacattg ttgatcataa
      961 tcatgacagc aattggcgca ggaatcggtt tttatttgaa acagtcagga atagttgatc
     1021 aattttttaa atcataggag gaaacaaaga tggaaaacaa aaacatgaat acaacaaatg
     1081 gatcagtttt ggcaaatgaa aaaggagaaa accgcatgat gaatggtgaa ttgacttatg
     1141 aagacaaagt catccaaaaa atcatcggtt atgcattgaa agatgtagat ggtctattga
     1201 cattagatgg cggatttttc tcaaatatgg ctgaaaaatt agtcaacaca gataacgtaa
     1261 cagcaggtat caatacagaa gtaggtaaga aacaagtagc tgtggatcta gatgtgatcg
     1321 tagaatacgg taaagacatc gaagatattt acaaccaaat caaagaattg atcagtactg
     1381 aagtaaacaa tatgacacat ttagatgtta tcgaagtgaa tgtgaatgtt gcagacatca
     1441 aaacacaaga agaataccaa aaagatcaag aaacagtaca agacaaagta acagaagcag
     1501 caaaatccac aggacaattt gcttcacgcc aaacagataa agcaaaatct gctgtaggca
     1561 aaggtgcaca aaaagtcaaa gaaaataacg aaccacgtgt acaataagaa gtaagaagtc
     1621 agttaggagg aatttaaaat gggatttatt tgggcattaa tcgtcggcgg tatcattgga
     1681 gcaattgcag gagcaatcac gaataaagga tcatcaatgg ggatcatcgc aaacatcatt
     1741 gctggtttag taggttcagc aattggacaa gctttactag gaacttgggg accaacaatt
     1801 gcaggaatgg ctatcattcc atcattgatc ggtgcaatca ttttagtatt agtcgtttca
     1861 ttctttgcac gtaaattata agcaaattga agaaaaactt atgttgaaat gaagaacaaa
     1921 tttgagaacc gtagcgacac tcgctgcggt tcttttttat atattttata tgaagtattc
     1981 tttattcct
//
LOCUS       DAYYEF010000143         1859 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000143 DAYYEF010000000
VERSION     DAYYEF010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.150"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            416..1804
                     /gene="ltrA"
                     /locus_tag="ACHA1B_002900"
     CDS             416..1804
                     /gene="ltrA"
                     /locus_tag="ACHA1B_002900"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA];
                     GO_process: GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HFM8703588.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
BASE COUNT          654 a          343 c          444 g          418 t
ORIGIN      
        1 aacttggtgg tgaaagtcca ctacaggctt ggcagtagga actgttagcg aaagacaagg
       61 cggcaatcgt gaggttgtgg ctgaaggaag tcggacgcaa actcctgaac tgacgaacag
      121 aaactagata caaggctgaa ttaggtcgga taagtcttca tcacaagaca aagtccaata
      181 ctgcccgaaa cctatacagt aaatctagca gttacatggg aggaaagttt tcactcttac
      241 cgggggagat ctcatgaggg tgttgtgggc gttgaatgaa aacaaaccag cacaacgatc
      301 atggcgacat gatggtgaat catgagaagt cagccgaggt catagtagta acgacactga
      361 ccgttacgaa ggactgaaca ataagaatct tgaataattt aggaggtgtg agaagatgcg
      421 acgaccgcag aaaacaagaa aacttggcta tcatcaaaga gctagtgtgg aacacgaagg
      481 gtatgatgaa gtgcgcagca cttcttgcgg tgaacagagg aaacaagatg gtgtagaaaa
      541 tctgtttggg agaattctag atcggaataa tctcaatcaa gcgtatcttc aagtagtcag
      601 aaataaaggg gcggctggtg cagatgggat gaccgtcgat caactgcttc cttacttgaa
      661 agagcaccgc gaggaattac tatccaattt acgccaaggg aactataaac ctcagcctgt
      721 tttgcgagta gaaataccga aaccaaacgg cggtgtaaga aaactaggaa ttcccacggt
      781 tattgatcgt atgcttcaac aggcaatcaa tcaagtgtta caaccgctat ttgaaccaga
      841 attctcagat aatagttatg ggtttcgccc aaatcgcagc gcacatgacg cagtgaagaa
      901 agcaaaatct tattatgaac aaggttaccg atatgtggtg gacattgata tgaaagccta
      961 ctttgacacc gtaaatcacg ataagctgat gtatttcatt gagcggaaag taaaggacaa
     1021 acaagtccta aaactgatcc gtcaatactt aatgagtggt gtaatggaaa atggactcat
     1081 cacaacaact gaagaaggaa cgccccaagg aggcaatctc tctcccctgt taagtaacat
     1141 ctacctgaac gaatttgatc aagtgctaga aaatctagga cataaatttg ttcgatacgc
     1201 cgatgactgc aatatctatg ttagaagcaa acgagcagga cagcgtgtga tgaagaaatc
     1261 cattcaattt ctcgaagaac aactaaagtt gacggtaaat cgagaaaaga gtgcggtagg
     1321 aagtccattg aaacgaaagt ttcttggatt ctgcattctg ccaacaaaga aaggtattaa
     1381 aattcgccct cacgcaaaag caaaacagcg tgtgaaaagc aagctcaaac aactcactaa
     1441 aagaaaccgt ggaagaagta tccaacttat tttaaaagaa atcaagcaac taatgactgg
     1501 ttggatcaac tactatggaa ttggtgagat gaaagaattc atgagggagt taaacggttg
     1561 gttgaagcga agaatcagac aatatatttg gaaacaatgg aagaatccaa gaaccaaaag
     1621 aaaaaatctg attcgtttag ggatcgataa agcgaaagcg tatgaatggt caaatacaag
     1681 aaaaggtatt tggtcagtct ccaaaagtca tattcttcat cgatcattaa cagacaaaga
     1741 actggcccgc caaggatatg aggacatctc cttgaagtac cagttcgtac actcaactta
     1801 ttgaaccgcc gtatacgggt ccgtacgtac ggtggtgtga gaggggcgga aggtcagtt
//
LOCUS       DAYYEF010000144         1853 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000144 DAYYEF010000000
VERSION     DAYYEF010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1853
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.151"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(198..1340)
                     /locus_tag="ACHA1B_002901"
     CDS             complement(198..1340)
                     /locus_tag="ACHA1B_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8703589.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(1345..1530)
                     /locus_tag="ACHA1B_002902"
     CDS             complement(1345..1530)
                     /locus_tag="ACHA1B_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HFM8703590.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
BASE COUNT          582 a          347 c          244 g          680 t
ORIGIN      
        1 caccggtggc aaaccggtgg caaatccatg taaacatggt ttatttttta cactgttttc
       61 aaacaaaccc ttgctatttc ttcggttcgt cctcgtccat tttcgatacc gacagctagc
      121 ttataaccca aggtatatca acataaaaaa ataaaaatag gctatgacag cagcgtgaca
      181 gcaaaaaaga tggaaagtta aatatcaaac ctcgtaattt catttgcgag tgcttgattt
      241 gtttctggat ataagtgtcc atatttgtcc aaagtagttt taatagaggc atgacctaga
      301 cgcttagata ttgcatagat atttttatta tgttcaatta aaaaggcaac atgcgagtgt
      361 cttaatccat gcatatgaat tggttttact cctgcaattt cagctagttt ttttattctg
      421 cttaaaatag ttcttggaga tggcggtaat ccatcaaaag aaaaaaccaa ttctatattt
      481 ttcccaattg attgttgagt ttttttccat gtttttaaat cttcaacggt ttgtctgtct
      541 aacgaaatta tccgaatact tgatgtattt tttgtttcag caaattcata atcttgtctt
      601 gtacggatgt aaattgactt atttacgcta catctgccat ttattaagtc aaagtctttc
      661 cattgtaacg ctaagagctc ctcactcctt acacctgtaa caaaaataaa acgcatcaaa
      721 cgtttataaa attcttcata aaaatccccg tgataaacac tattatatac tttcttaaat
      781 tcatcaactg tccaaaattc tacttgagga cgctgagttt ttattttacc tatagtatct
      841 acaggatttt cttcaataat ttcaagtaca attgcccttt taaaaactac tctcaactta
      901 ttgaatatct gtttaatata atttggtgat aatggttgct caatgccctt ttttacaaca
      961 tggattttcg ataaaaactg ttgaaattcc tgtatatgaa ttggtcgaat ctttacaacc
     1021 tgcatttctc caaaaaaatc caatgcacgt tgtaaaatat gatctgtttt catatatgtt
     1081 ttttctacag ttcccaactt ataccaagga aaaaaatact ctcgataaaa atcatgaaac
     1141 gttattcctt gcagataaat tccttgtgaa tcagaaaaac tttgttttaa ctcttcgagt
     1201 ccccttctag cttctccttg agttttgaag cctcttctgg tcacttgaat tctttttcca
     1261 aagcgatctt gtcctaaagt tgcagaaaaa aaccaagtgc ctctttttct gtctttataa
     1321 acattcgcaa ttttcctcat tttactattc ctcccaagaa atatggagaa cttcttctaa
     1381 aattgaaata ggaattcttt ttatttttga attacgataa aaaaagtatc ctttctcaac
     1441 taaaagttct ttacattcct tgaagatttt attagcatag tactgagaaa aacctagatt
     1501 aatcaaatct tttcgagtag ctgttttcat tatagcacct tccttacttt ttttcattta
     1561 tttctatcag ctgcttttgt caaaagcaca taggaatttc acctctcccc aagtttacgg
     1621 cgagccttac ggaagtatca ttatcccaac tttaaatcat cgctttttat tgactataaa
     1681 aattatttta gaatatttat cgctccttct ttacagcaag aaatcatggc gcaactaaaa
     1741 tatgctcctt aaagtgttaa cgtactgata gaatctattt aattttcaat gaacaatagg
     1801 ttttctacct aaaagaatct actaattcct taactattag aagattcttt taa
//
LOCUS       DAYYEF010000145         1639 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000145 DAYYEF010000000
VERSION     DAYYEF010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1639
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.152"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1135
                     /locus_tag="ACHA1B_002903"
     CDS             <1..1135
                     /locus_tag="ACHA1B_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="C47 family peptidase"
                     /protein_id="HFM8703591.1"
                     /translation="KKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQPIEEQAIN
                     FAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFSDADNTIK
                     YIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNGQIKLLWK
                     SPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDNFIMINWR
                     IAETQTSFPWCAAYVEAAILCNKTDVRATSARAIMHYTYPNLNNSQIESKSLNQDQII
                     KYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALALFGWVNQG
                     GYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1108..1551
                     /locus_tag="ACHA1B_002904"
     CDS             1108..1551
                     /locus_tag="ACHA1B_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703592.1"
                     /translation="MGQYHYKLVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLG
                     TWQTKDHSERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNL
                     LTLRSNKKQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
BASE COUNT          629 a          264 c          239 g          507 t
ORIGIN      
        1 aaagaaaatt tatctaggtc tcctcttttc cttgatgatt ggaattttta gtataggaat
       61 tacaaatacc tatgcttcag aaaattctaa tttcaatatc aactcccaac caattgaaga
      121 acaagcaatt aattttgcga aaactgattt tgaacactcc ataacttcaa ttcttttaat
      181 ggaaaataac accgaaactg atattaacta tactcttggt tcgccattta aaatgctcga
      241 tggagaaaat acggcaaata gttctatttt ctttccagta ttttcagacg ctgataatac
      301 gattaaatat atttataccg tcaaaaaaaa tacaaatgga gaatattcag gaagtatctc
      361 acaattttta gcaaaagaac ttcaaaatct agtagatagt aatataacag atacaacctt
      421 attttttcaa gataatagca tttattattc cgataatgga caaattaaac tactttggaa
      481 atcaccttta agtacagaaa aaaatggtgt ttcttccttt acagaaaaaa atgatcttat
      541 atccgtaaat ataaaaaata aaattaaaaa tttctctaaa aaacaaaatt ttcctgcggt
      601 taaacgtgta aaaagtgtct cctccggaga taactttatt atgattaatt ggcgtatagc
      661 agaaacccaa acaagttttc cgtggtgtgc tgcttacgta gaagctgcta tcttatgtaa
      721 caaaacagat gtacgtgcta cttcagctag agccattatg cattatacct atcctaattt
      781 aaacaacagt caaattgaat caaaaagtct taatcaagat caaataataa aatatgcaaa
      841 ttactgtggt gtttatccta aaaaagtagc acgaatacta aacctttcag aggtccaaac
      901 acaactaaga aaaggaaatg ccatttatat gggaactgct ggttatggaa attatagtaa
      961 cagccgtcat gcacttgcat tatttgggtg ggtcaatcaa ggtggttatc aaacttacta
     1021 tgtgtggaat ccttggtata actacccaac tgtaataagt gcaaatgcag gaccagttac
     1081 aattcctgta cctggaggtg gttttacttg ggacaatacc attacaaatt ggtaaataaa
     1141 cccattgctt tagttatggg tctagtgtta gttcttttct taactagttg ttcaaaaaaa
     1201 caagaaatac aaaagactga tctgattcct tttctaggaa cttggcaaac taaagatcat
     1261 tcagaacgtc tagtaatcac taatttaaat acttcaaaaa atatagaaca atataccatc
     1321 ttagtaaaag agaacaatca taaaattcaa atcattgata aaaatttaaa tataaatgaa
     1381 caagttttca tttacaaagc aacaaataat ttactaacac tgcgctctaa taaaaaacaa
     1441 ttagattaca cttttagttt ggattctcca aaaaagctcg tatttatttt gacaacgaat
     1501 gatgggacag aagggacagc taaaccaatt gaatttttta aagctgattg atgaatagtt
     1561 gtttgatatt acaaaacaat aatttcaccg aaggtgaaac aagcgaaact ttacaaaaag
     1621 tggctagcat ttgctagcc
//
LOCUS       DAYYEF010000146         1573 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000146 DAYYEF010000000
VERSION     DAYYEF010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.153"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            123..1292
                     /locus_tag="ACHA1B_002905"
     CDS             123..1292
                     /locus_tag="ACHA1B_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HFM8703593.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          558 a          255 c          258 g          502 t
ORIGIN      
        1 ttttacactc tctattatga tagcgtaaaa tattttgtgt aaatagaaat ttagggtaga
       61 aaaaaaagtc cattctgtaa aattaaagtt accacacaga aattttatag gaggactttc
      121 tcatgactaa atttactata gaaattatgc aaacactact caataaaggg gatttagatg
      181 aattatttca ggatcattta gagcgagcga ttaattcact tctacaagca gagctaactg
      241 cttttttaga ttacgaaaaa tatgatcgaa atggattcaa ttcaggaaat tcccgtaacg
      301 ggaattattc acgtacattt aaaacagaat atggcgagtt gaatttaact attcctagag
      361 atcggaatgg cgaattttct caacaaacac taccagcata taagcgaacc aatgattcat
      421 tagaaacgac cattatccaa ttatttcaaa aaggcattac tatggctgaa atctccaaat
      481 taattgaaaa aatgtatggt caccactata cgccacaaac aatctccaac atgagtaaat
      541 tggtggctga agatgtttta gcttttaaag aaagaacgtt agaagccaat tattccgtta
      601 tatttatgga tgcgacgcat atccctgtga agcgacagac tgtttcgaag gaagcagtgt
      661 atattacgat tggtattcgt ttggatggaa ccaaagaagt tcttgggttt actattgccc
      721 caactgagtc tgcttatatt tggaaagaag ttcttcaaga tcttagaaaa cgtgggttag
      781 aagaagtttt attagtagtg acagacggat taagctgtat tgaagaaagt atccatagtg
      841 tgtatccgaa tgcccaattt caacaatgtt gtgtgcatgt atctagaaat atcgctcata
      901 aagttcgtgt tcgaggtcga aaagaaattt gtgaggattt caaattggtt taccaagcga
      961 attcaaaaga agaggcattg gatcacatcg actttatgac taggaaatgg aaaaagcagt
     1021 atccaagagt cgtcaattta ctcttgaatc ctgccctatt aaccttttat aatttccctc
     1081 acgccatcag acgaacaatt tattcgacga acctgattga aggctttaat aagcagctaa
     1141 aacgatatac tcgaagaaaa gaacaattcc ctaatgaaga atctctagag agattcttca
     1201 tttctcaatt taatcaatat aaccaaaaat ttttaggtag aattcacaag ggatttaaag
     1261 aaattcagga tacattagag tcgatgattt aactgtaatt aacagaatgg attttccatt
     1321 tacatataat tcttgacgct accataatct aaataaccat catattcatc tactacttat
     1381 ataattgagt tttattaaac tttttaagtt tctattctat caaatattta aacaatctct
     1441 gcatccgaaa agactacctc gtatagtttt actaacaata tttttattag cgtgttcaaa
     1501 tcctgatttc ttgtatcaat tattttctgt tcactttcaa taagaaaaaa gtctttactt
     1561 ccatggataa taa
//
LOCUS       DAYYEF010000147         1480 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000147 DAYYEF010000000
VERSION     DAYYEF010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.154"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            95..505
                     /locus_tag="ACHA1B_002906"
     CDS             95..505
                     /locus_tag="ACHA1B_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFM8703594.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            519..875
                     /locus_tag="ACHA1B_002907"
     CDS             519..875
                     /locus_tag="ACHA1B_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HFM8703595.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          542 a          210 c          272 g          456 t
ORIGIN      
        1 ttattttgat tttttttata ttttattagc taataattgg tattttaaaa gaaattactg
       61 tagaattgga ttataattaa aaaggagtga gaaaatgata aaagtatata cttcgcctag
      121 ctgtacttcc tgtagaaaag caagagcatg gttgcaagcg aatcaacttg aatttgaaga
      181 gaagaatatt tttgccgaac cgttaacaga aagtgagatc aaaaagatct tggcagcgac
      241 tgaaggagga gttcaagata ttatttccac tcggtcgaaa atttacgaaa agctgggcat
      301 agattttaac gaattaactt taaagcaaat gatcgtctta ttcaaagaat atccttcatt
      361 attgagacga cctattttga ttgatgaaaa aagaatacta atcggattta atgaagatga
      421 gatccggtca tttgtccctc gtgaaattcg atgtgttgcc agaaatctga tctatttaca
      481 aaacaataac atcttaaatt catagggagg gagccttcgt ggaagtgaaa gtctatggat
      541 cagcgcactg tgtaacaagt ctgaaggcga aacaatggtt agaacaccat caattgcctt
      601 atcaatttgt tgacttagaa gaacgcgatt taagtacaga agaagcagaa gaattatgca
      661 gttttgaaga agtgcaagca gaacagctat ttgcgacttg gtctgaggct tttcacaaca
      721 ttgcgattga cctttcctgt gtaggaaaaa aacaactgat ttttttatgc acacaacata
      781 ccaatctcct cagacgtcct ttgattatta tcgatgaagt tctatttatt ggatacaatg
      841 agcagttgat ggaacagctt atcttaaata aatagacttt aactgtttta atcaagtcac
      901 tgagcatttc atacagttgt aacagtcgaa cacttagcat caagcgtgtt atgtgttctt
      961 tttttgactt tatttttcta ctatagagac atgctcaatt tatgtggtca aaattcaaat
     1021 ctaggtgggg atatagagtt aaaaatatat tgacatgtgt aaatttacat gatatattca
     1081 tttctgttgt tttaagtagc aaagcaataa aatagtattt taaaaaacat ataaaatagt
     1141 tgttgacatg ttagaaatga catgataaga taactgagtt gttaaaaaag aaccacttgt
     1201 gaagcttgat tctatcgaaa aaaacttcaa aaaagttctt gacaaataac aaatgataag
     1261 ttatgataaa tgagttgctg taagatttcg aaaaacgaaa tcaaaaaaac ttttaaaaaa
     1321 gagttgacaa ttacttgtct ctctgatatg atataaaagt tgctacggca gccaaaaacg
     1381 aatcggggaa cactcctgat gaagtagacc tttgaaaact gaacaaagta agacaaacca
     1441 aatgtgtagg gcgtcttgat tcaattcaag acaacaaaca
//
LOCUS       DAYYEF010000148         1475 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000148 DAYYEF010000000
VERSION     DAYYEF010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1475
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.155"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..95
                     /locus_tag="ACHA1B_002908"
     CDS             <1..95
                     /locus_tag="ACHA1B_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="bacteriocin 32"
                     /protein_id="HFM8703596.1"
                     /translation="VNIRGKQTMRTCYLMSWNASSRTAKYYYYI"
     gene            901..1074
                     /locus_tag="ACHA1B_002909"
     CDS             901..1074
                     /locus_tag="ACHA1B_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703597.1"
                     /translation="MLKKTVLVLGSISLGILGFSPMLLSVIGKNNSNRELKLNSNYYN
                     SPNEELFVKQTDK"
BASE COUNT          563 a          217 c          228 g          467 t
ORIGIN      
        1 tagtaaatat tagaggtaaa caaactatgc gtacttgtta ccttatgagt tggaatgcta
       61 gtagtagaac agccaaatat tattactaca tttagtaaaa acaaaacatt ctttctatac
      121 aataaaatag cgtatagaga ggatgttttt aatttgaaaa ggagtggtta tctttatgaa
      181 aaatagatca tttgctatat tagtattatc cgtaatttta ttagatatat tgttaataac
      241 attagcttta aaaactttaa atttagtaac aagttttgtc attataccag taattatagg
      301 aatgtctatt tatttcatca aaaaaaataa acaatttttt tgaatgaaat tacgggcgaa
      361 aataatcact caaaattatt aataaaaacg aatcaactac tttttctgaa gaaacataca
      421 accgtaaaca acaattgttg tttacggttg taaattatca aactatatgg tgacttgttg
      481 cttaaaatag gttgaaattt cgtttatttt ttttgagaaa ttttacccac gtactaccca
      541 tgtacctatc cacgtattac ccatgtaccc ccccatgaca aatgggcgga ggggcttgcg
      601 gcgcttggta ttaaaggcat tatccgcctc ccaggtttct gaccattttc tctcataagt
      661 ggggttttta ccgcgttgag agaaaatggt cagaaaccta aacgatcggc aaagaaaaca
      721 taccaagcgc cacaagcaaa aaaagttaga gtaacttcca gaaaagaaaa atttttagaa
      781 caacttttga aaatttgatt ttgatttata tccgttcaat ttaaacattt gataaactga
      841 aggctagtat ttaaaatgtg tatacaagtg gtagcgttaa aaaaagtgga ggtataacct
      901 atgttaaaaa aaactgtgtt ggtactgggt tctatttctc taggaatatt aggttttagc
      961 cccatgctat tatccgtaat tggaaaaaac aattccaaca gagaacttaa attaaattca
     1021 aattattaca acagtcctaa cgaagaattg tttgtaaaac aaacggataa ataataaaaa
     1081 agactgctct ttcgagcagc cagttaaaaa ataatgagtg tttattcttg aaaaagcacg
     1141 cgcttatgaa gcgctaccaa aaatttacca tattttacaa aaaataacaa gtcttaaaaa
     1201 aatgacagat aaaaatgcac aaagaattag atatagataa ccgcgaaaaa tcaagcttta
     1261 gaaagttgct tttagctaga ccaattaaaa atcacaaagt gagcgtctct atccattggt
     1321 agaggggcta cttggcatag tgtacattat gttaactaac gctataaata acgattatgt
     1381 tcccaaaaca atattttatg aactataaca aaaatttgtt atcgcatatt gtatatttta
     1441 attataggtg tataccactt aaatttaaca caaag
//
LOCUS       DAYYEF010000149         1444 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000149 DAYYEF010000000
VERSION     DAYYEF010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.156"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..390
                     /locus_tag="ACHA1B_002910"
     CDS             <1..390
                     /locus_tag="ACHA1B_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM8703598.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
     gene            813..1444
                     /locus_tag="ACHA1B_002911"
                     /pseudo
     CDS             813..1444
                     /locus_tag="ACHA1B_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          512 a          262 c          251 g          419 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggagga caatttattt
      421 acacaaaatt attgacgctc cctgtttcaa agttagtaga gaaaatgtag ttatatattt
      481 aaatttttac cagaaagaaa tgaacacctt caattatcta aatctcgaaa atggttagat
      541 gtaatcatca ggaaaaacaa tcttaaacga attactattc atggtcttag acacacacat
      601 gctagcttgc ttttagcaag ctagtgcaaa tattaaagat gtgcaagagc gtttaggcca
      661 ctcttctatt caaatcatta tggatctata tattcatatt acagacaaaa gaaaagaaga
      721 aaccgtagcg caattcgcaa aatataggct ctataattta tgggactgat gaatcaaaat
      781 tgattcttca gtcccattgt tattttaggt atatgattcg tacattgaaa gagttgaaaa
      841 actatcttcc gaagccgtca aaaaggaccc tgccaaaagt attgatggtg gatgaatttc
      901 gttcgcacgc ttcaattgtg gataaaatga gctttatttg tgcggatggc gagactggaa
      961 aactcattga tattttgcct acacgaaaat tgtctcgatt aacacactat tttagtcgct
     1021 gtgcaaatcc tgaagcggtg gaatatttag tgacagatat gaacgccgcc tacttccaac
     1081 tgacaaaacg tgtcttacca aatgcgaaag tcgtcattga ttgttttcat atcatcaaac
     1141 atttgaatca ggcgttcaat gattttcgtg tacaagaaat gaaaagatta caccagttag
     1201 ggcaacgacg ggaagccgag aaagtgaaaa agaactggcg ctttcttcta aaaaaccgtc
     1261 aaaaaatcaa tcactatgat tacaaaacat ggcgcagttt tcgtgcacct aaatacccgc
     1321 tactcactga agcaatgatg attgatcgat tgctggcatt ttcaacgcct ttaaaggacg
     1381 cctatacttt tttccatgag ctgaccgaag cctttagaga caaggaatca gacttatttt
     1441 ttac
//
LOCUS       DAYYEF010000150         1434 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000150 DAYYEF010000000
VERSION     DAYYEF010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.157"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(13..1152)
                     /locus_tag="ACHA1B_002912"
     CDS             complement(13..1152)
                     /locus_tag="ACHA1B_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HFM8703599.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT          374 a          308 c          260 g          492 t
ORIGIN      
        1 attaaaaaaa tcttacgcta agtaggataa aataattcct tgatattttt cgatcatatc
       61 caaataatta tcgatttcaa catactcatc tacttgatga ggcaaagtaa cgacaccagg
      121 cccaaagacg acaaagtcga aggaatggtt agctttcgta aattcggctg catccgttgt
      181 tgctgccgct ccaactaaag gtaatggctg gctgaattgt tgctgaatgc aatgaatcaa
      241 aggagaatct ggatcagctt tgacaggtat tttgttgtaa tcgatcatca attccaaatg
      301 atagtctgtc tcttgattca attcattgac gattgattgc agcaatgcaa tgattttatc
      361 atttgggtat tctggaatcg atcgaatgtt cccttggagc tgcgcatggc ttgggatgct
      421 gttgacttga ttcccgccac tgatcaatgt aacattatgg attgtttttc ctaggacagg
      481 attctcgatt gtttcagcga ggtgattcat ttcagcattt gctttcgtaa tgaattcatt
      541 taggtgattg attgcattat aaccttggtc tggcatagag ctatgcgctt cttttccgtg
      601 cgaggtgact gtatagttga ttgatcccat gtgcgtatac atcaaactgt aattggttgg
      661 ctctccgatg atcaaggcat ctaagtcatc tacatagcct gctttcgtga gctgttcccc
      721 acctagttca cccacttctt ctccgacagt ggctaataat ttgactgttc cgttaaatgg
      781 ttttcctgac tctttcagtt cgatcatggc aatcaccatt gctgccaagc cactcttcat
      841 atctgtagca ccacgtccgt acaaacggtt cccatggatt tctgctgcaa agggtgcata
      901 ggtccaagac gattcatcac cagccgccac gacatccata tgtccagata ggcctaacac
      961 ttttcctgat tggccctttt ggtaacgagc aatcaaatta tctctaccat ctctgtaaga
     1021 aacaatctct cctgttatgt catgctttgc caaaagctta ttcaaatagg ctgctacttc
     1081 accttcgttt ccattcactg atttaattcg gataatctct tgtaaaatcg cgattttttc
     1141 ttcttttttc atctaatcct ctcccttgcc atttcttttt attgtatttg agtgtgctcg
     1201 aattttcaaa taggagcaac caaagtaaaa atgaagaaag agagccactt tatgaaaaat
     1261 atgctgctac ttccctccta ttttatttat acgagaggac ttgcccatag attcctattc
     1321 tactgttcta tccttaaaag ctcttatatg atgctagtta ttgttagctt tcctttttca
     1381 aggatgatct tttcttgtac cattctttgt aaacatcata tacagaagct agtt
//
LOCUS       DAYYEF010000151         1424 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000151 DAYYEF010000000
VERSION     DAYYEF010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.158"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(150..1337)
                     /locus_tag="ACHA1B_002913"
     CDS             complement(150..1337)
                     /locus_tag="ACHA1B_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HFM8703600.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAYYEF010000152         1420 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000152 DAYYEF010000000
VERSION     DAYYEF010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.159"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="ACHA1B_002914"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="ACHA1B_002914"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HFM8703601.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          496 a          184 c          236 g          504 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtca ctattactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctggactaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta acttattgct tttgcaaaat ttatttacct gttttctgga tcaacgatag
     1141 tgtatattat gctatccttg tttggatttt aggacgttta aagaggcact tttttacata
     1201 acttaatcca tagacctttt aagcatgctg tgagataata ataaagaaga gtttaaagcg
     1261 caccccaaac cacttcccca taagtgtatt acgctttaaa ctcttttata tttgaattca
     1321 ctaagaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttataa ttaggattta
     1381 gagtaattaa ttagatgttt attttatagg actgatacta
//
LOCUS       DAYYEF010000153         1337 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000153 DAYYEF010000000
VERSION     DAYYEF010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.161"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1337
                     /locus_tag="ACHA1B_002915"
     rRNA            <1..1337
                     /locus_tag="ACHA1B_002915"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          358 a          293 c          406 g          280 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa gtacagtgat gtatggagcg gactgatact
     1321 aatcgatcga ggactta
//
LOCUS       DAYYEF010000154         1334 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000154 DAYYEF010000000
VERSION     DAYYEF010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.162"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..365
                     /locus_tag="ACHA1B_002916"
     CDS             <1..365
                     /locus_tag="ACHA1B_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM8703602.1"
                     /translation="PLTEVEIFHTDRGKEFDNQAIDELSTTFDINRSLSHKGCPFDNA
                     VAESTYKSLKVEFVYQYTFETLQQLDLELFDYVNWWNRLRLHGTLGYETPVGYRNQRL
                     AQRILDNELGCANASEAV"
     gene            637..>1334
                     /locus_tag="ACHA1B_002917"
     CDS             637..>1334
                     /locus_tag="ACHA1B_002917"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008446 - GDP-mannose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_function: GO:0070401 - NADP+ binding [Evidence IEA];
                     GO_process: GO:0019673 - GDP-mannose metabolic process
                     [Evidence IEA];
                     GO_process: GO:0042351 - 'de novo' GDP-L-fucose
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HFM8703603.1"
                     /translation="MKKALITGITGQDGSYLADFLLEKGYEVHGITRRASISNTARID
                     HLMGKITLHDGDLSDSSSLIRIISIVQPDEIYNLAAQSHVQVSFDVPEYSGDVDALGV
                     MRILEACRILGLTKKTKIYQASTSELYGKVEEVPQRETTPFHPYSPYAVAKQYGFWIT
                     KEYREAYGMFAVNGILFNHESERRGENFVTRKITLAAGRIAEGLQDHLELGNMDSLRD
                     WGYAKDYVECMWMIL"
BASE COUNT          359 a          284 c          303 g          388 t
ORIGIN      
        1 aacctctgac agaggttgag atttttcata ctgatcgtgg aaaagagttt gataaccaag
       61 ctattgatga attatcaaca acttttgaca tcaatcgatc attgagtcat aaaggctgtc
      121 cttttgataa tgccgtagct gaatcaactt ataagtcgtt gaaagtagaa tttgtctatc
      181 aatacacatt tgaaacctta caacaattgg atttggagtt atttgactat gtcaattggt
      241 ggaaccgcct tcggttgcac ggtacacttg gctacgagac accggttggt taccgtaacc
      301 agagattggc gcagcgaatc cttgataatg agctcggatg tgctaacgct agcgaggcag
      361 tctaacttta actgttagct cctgccgaag atcgtcacat ccgaggaggc tcattgtcaa
      421 ggacaatcgg aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac
      481 tgttgccatt ccaattcacg aaaaactaat attgtgctaa tgcgtgcgta gattgttcta
      541 tgaaatatcg aaaattatcg tgtattcttg aaaagtatta gaaattacga gccatttata
      601 tggccttatc acttacatag gaaaggataa tgtatcatga aaaaagcgct gattactggt
      661 attactggtc aggacggttc ctatctggca gatttcctgc tagagaaggg ctacgaagtt
      721 cacggtatca ctcgccgtgc ttctatttcc aataccgctc gcattgacca tttgatgggc
      781 aagatcaccc ttcatgacgg tgacctgtcc gactcatctt ctctgattcg tatcatcagc
      841 attgttcagc ctgatgaaat ctataacctc gctgcacaga gccatgttca ggtttctttt
      901 gatgttcctg agtactccgg cgatgttgat gctttgggcg ttatgcgtat tctggaagct
      961 tgccgtattc tgggcctgac gaagaagact aagatttatc aggcatctac ttctgagctg
     1021 tatggcaagg ttgaagaagt tcctcagcgt gaaaccactc cgtttcatcc ttacagccct
     1081 tatgctgttg caaagcagta tggcttctgg atcactaagg aatatcgtga agcttatggc
     1141 atgttcgctg tcaacggtat tctgttcaac catgaatccg aacgtcgcgg tgagaatttc
     1201 gtcacccgta agatcaccct cgctgccggc cgcattgcag aaggcctgca ggaccatctg
     1261 gaactgggca acatggactc cctgcgtgac tggggctatg caaaggacta tgttgagtgc
     1321 atgtggatga ttct
//
LOCUS       DAYYEF010000155         1334 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000155 DAYYEF010000000
VERSION     DAYYEF010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.163"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            86..1165
                     /locus_tag="ACHA1B_002918"
     CDS             86..1165
                     /locus_tag="ACHA1B_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFM8703604.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
BASE COUNT          359 a          357 c          369 g          249 t
ORIGIN      
        1 agccatttgg aaataaaaaa acgccacgtg aattccatgt tatattgaag ttaccacaac
       61 tctcaataga caaggatgaa ttcacatgac gcaaaaccat gataacacag tttcacgcaa
      121 gggaaaacac ctaacctact cagaacgttg ccaaatcgcc atcctgaaaa aggaaaacta
      181 ttccaaccgt caggttgcgg atgtcctggg ctgcgtgccg cagaccataa acaacgaaat
      241 caaacgcggg accgttactc agcttaaccg ccagaatcag aacgggaagg tctacgacta
      301 ttatcatgac gtctacgacg ccgatgccgg gcaggcggcc tacgagaaga accgcttgaa
      361 ctgcggcaga cggcccttat gggccgacac ggacgccttc attgaatggg cggacgacat
      421 gatgctgttg gaaaaatggt ccccggacgt ggtggtgggc tttgccagaa aacacgaatt
      481 gttcgacccg gccattatcc ctgggaccac caccctctat cagtggatcg accgtggcat
      541 catgaaaacg aagaatatgg acctgctaga aaaactgtcc cgcaaaccga aatcgtcccg
      601 tcatggcaac cgcccgaata aacgggtgct agggaaatcc attgaagagc gcccggaggc
      661 ggttggtacc cggaaaacct tcggccattg ggaagtcgac acggtcgtag gaaacaagac
      721 caagtcggat gccgtgctgc tgacgttggt ggaacggcag acacgcttcg aggtcattct
      781 gaagctggcc gggaaggatg ccgaatcggt caaccaagcg gtccgacagc tgagagaacg
      841 ggctggtgcg tacttcggcc agctgttcaa gacggttacc tcggacaacg gctcggagtt
      901 cgcgggactg cacgatgcct tgcaggatgt ggcaaacatc tacttcagcc acccctatgc
      961 ttcctgggag cgcgggacga gcgaaaacca acacaagctg attcgccgtt tcatccccaa
     1021 gggcagccca atcggcaacg tgagcgaaaa ccaaatcttg cggattcagc gttggatgaa
     1081 cgattacccg cgaaagattt tgggctatgc aacgccgcat gacacgttcg tccaggcatt
     1141 taggcaggaa cggttgacgg cttgacacgt gggcccttga caacgagcct ccctcggcat
     1201 ggcttgtgtc tggaaagctg gccggggcca gccagtcggg agactaccat gcctcagctc
     1261 attgtcaagg gcccactcga ttagaaaaat tagacggttg gtggtaacga gcaaccgggt
     1321 caccatgggt ggct
//
LOCUS       DAYYEF010000156         1330 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000156 DAYYEF010000000
VERSION     DAYYEF010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1330
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.164"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            111..983
                     /gene="scrK"
                     /locus_tag="ACHA1B_002919"
     CDS             111..983
                     /gene="scrK"
                     /locus_tag="ACHA1B_002919"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008865 - fructokinase activity [Evidence
                     IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase ScrK"
                     /protein_id="HFM8703605.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT          411 a          234 c          309 g          376 t
ORIGIN      
        1 aaaaaatagt agttatttac ttgtcatgtt actaaataaa aaaataattt aaatatgata
       61 tatagtcatt tatttagtga tttcattcta aaataaaggg agaaatgtct atgctatacg
      121 gtgcaattga agcaggcggc acaaaatttg tgtgtgccat tggcgatgaa gaaatgacga
      181 tcaaggaaag agtgagcttt ccgacaacga cacctgagga aacaatgcct ttagtcattg
      241 acttcttcaa acaataccaa gcagatttag cagggattgg gattggctca tttgggccta
      301 tcgatatcca tcgcgattcc gccacttatg ggtacattac ctcgaccccg aaattggcat
      361 ggcaaaattt tgatttcatc ggtaccatga aaaaagaatt tccgatcccg atttcttgga
      421 caacagatgt caatgcggct gcctatggtg agtatgtctt cggcagtggc aaaggattga
      481 gcagtgtcgt ttactatacg atcggtacgg gtgttggcgg cggtgcctta caagaagggc
      541 gctttatcga agggtttagt catccagaaa tggggcatat gctcgtcgtc cctcatccaa
      601 aagatgactt tgctggcagc tgtccatttc atggcaactg tttagaaggg atggccgctg
      661 gacccgccat cgaaaaccgc ttagggaaaa aaggacaaga ggttgcagaa gatgatcctt
      721 attgggaaat cgaagcctcc tatattgctc aatgtgccta caatacaacc ttgatgtttt
      781 ctccagatgt gatcattttt ggcggtggtg tgatgaaaca acgccatatg ctgcaaaacg
      841 tccacgacgc atttgcaaaa ttggtcaatg ggtatgtcga aacacctgag ttaagcaaat
      901 atatcgtgac cccagcatta gaagacaacg ctggaacgct cggttgtttg gcattggctc
      961 gagaagcggt cttacattca taaacgaaaa aaggctcttc gacatttagt gttggtagag
     1021 aaagatacaa ctgaaaattt agtcataacc agttaggcag agtgcttaac tggtttttgt
     1081 tttacttgga agatcaagcc ttgaatgaga taaattcttg ctcgaaagtt atggaaattt
     1141 cgatagccgt aggccacttg tattgtgcaa tagtttttta caaaaaaaag ggggtgcgga
     1201 tatttttttg gaccttttta acaaataggt tctgttgcaa agttttaaat ctactatcag
     1261 ataaggtaga ataatagaaa aagatagcag gaggaatgac gatgagtcat tttaaaggaa
     1321 agcaatttca
//
LOCUS       DAYYEF010000157         1327 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000157 DAYYEF010000000
VERSION     DAYYEF010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1327
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.165"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            92..>1327
                     /locus_tag="ACHA1B_002920"
     CDS             92..>1327
                     /locus_tag="ACHA1B_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFM8703606.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRN"
BASE COUNT          417 a          264 c          255 g          391 t
ORIGIN      
        1 accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc tttagaatta
       61 atttggctac caattcatag gaggattcaa gatgtctcat actcagctta tcaaagatac
      121 cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta aagaaaaata
      181 caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag aagagtgttc
      241 ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa ccgttcggtt
      301 gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac aacgatttaa
      361 atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa aacactgttt
      421 cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata cttccatgac
      481 ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca tgaagcgatt
      541 ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct ttgatgaatt
      601 caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg gacaaagcca
      661 tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct atttttctcg
      721 gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt atgcgcctta
      781 tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc gtttccacat
      841 cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca cggtacgact
      901 taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct attggaaact
      961 cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg ccagttttaa
     1021 agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc ccaacttacg
     1081 ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag atcagtcact
     1141 atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata caaccacttt
     1201 acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca gctattcaaa
     1261 cggaccattg gaatgcttaa acaaccacat caaagtatta aaacgcaatg cgtacggctt
     1321 tcgcaac
//
LOCUS       DAYYEF010000158         1314 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000158 DAYYEF010000000
VERSION     DAYYEF010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1314
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.166"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>1314
                     /locus_tag="ACHA1B_002921"
     CDS             82..>1314
                     /locus_tag="ACHA1B_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HFM8703607.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGF"
BASE COUNT          444 a          257 c          251 g          362 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg attt
//
LOCUS       DAYYEF010000159         1313 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000159 DAYYEF010000000
VERSION     DAYYEF010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.167"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            200..742
                     /locus_tag="ACHA1B_002922"
     CDS             200..742
                     /locus_tag="ACHA1B_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703608.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..1313
                     /locus_tag="ACHA1B_002923"
                     /pseudo
     CDS             898..1313
                     /locus_tag="ACHA1B_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330699.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA disulfide reductase family protein"
BASE COUNT          532 a          148 c          256 g          377 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgt ggaatggcaa
     1261 cacttttttt gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gct
//
LOCUS       DAYYEF010000160         1311 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000160 DAYYEF010000000
VERSION     DAYYEF010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.168"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(50..349)
                     /locus_tag="ACHA1B_002924"
     CDS             complement(50..349)
                     /locus_tag="ACHA1B_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5960 family protein"
                     /protein_id="HFM8703609.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(355..585)
                     /locus_tag="ACHA1B_002925"
     CDS             complement(355..585)
                     /locus_tag="ACHA1B_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703610.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(844..957)
                     /locus_tag="ACHA1B_002926"
                     /pseudo
     CDS             complement(844..957)
                     /locus_tag="ACHA1B_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
BASE COUNT          452 a          216 c          200 g          443 t
ORIGIN      
        1 aagtatggtg ataaaatccg ttccgggcta cctttttagg tagcctactt taatctttgt
       61 atctttctgg atcaacgaaa gtatacttta tatagtcata acgccgatga tcgcttcgag
      121 cgtctagcac atcagtcacg atatcaaaca aaaaatatac gtctttcttc attctagttt
      181 tcgcagcagg gattttaaag tagttcttat tagaatagta gagattaatt aataagctat
      241 cttcgattgc taaaaagaaa acttctgaat cccacacctt ataaaaatct ttgacaaatc
      301 tattcgaagg atcaaattta aaccataatt gcgtctcatt aaaaagcata accattactc
      361 cgatctattt ttaaacttag tctctacctc taatatatat cgagttttta ttttgccttc
      421 agagaatact gtttcttttt ttgcagttac aggttgttta ttttcggaaa aagctaatat
      481 agctaaaatt gaaacatcca tctggaattt gtctttttcg ttgctttgct cataaaaatc
      541 tgcatattca tcactaatat tttttctaat aaattcttcc atcataaaga tcacctcgaa
      601 aagagtatac gaacaaacgt tctttttgta aaggtggaat ttattatact aaataaatag
      661 gtgaacaagt acttgtgcca aattatgtgc caaaaaaaat cgaatttaat aaaacacaaa
      721 caaaaagaaa tcctattatg ataacatttc ttataataac aaacacaaca gaagacgtgt
      781 aatagttagt caggaacgta caaataaccc ctgtatcctt tgcggtacag ggggttattt
      841 tgtataagta gacattgtag tttctaaact gctatgtcct aaacgtttcg atacgctaag
      901 tatatttact ccttgataaa gtaaaataga tgcatgcgta tgtcttagtc catcaataaa
      961 cagtcgaaga gaaaataggg aaaaattgat tactaaagaa aaacttacta ggtcgacggt
     1021 gtagttgatt ttcatacttc aatagattcg aattaaacga tttcgattgg cttataccag
     1081 tcctatccaa cgaaagatat atcgttctta actctagcgg tataacttga agctttacgt
     1141 aaagccaatg ggaatgaact ggagatgact ttttattatt tttagtaata gctgatgggt
     1201 taatacttac aactttcctt ttcaaagtac catataaaaa aacggtgggg ttgtttagcg
     1261 aaataaagga tctaagccaa tagcttagat cctttattct atgctttata t
//
LOCUS       DAYYEF010000161         1275 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000161 DAYYEF010000000
VERSION     DAYYEF010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.170"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            81..1253
                     /locus_tag="ACHA1B_002927"
     CDS             81..1253
                     /locus_tag="ACHA1B_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HFM8703611.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT          476 a          234 c          227 g          338 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccattagaa aatccttcac caacgtaagt tggcaaagat
      841 gccaagttca cttcctaaga aatatcttta ccaccattcc taaaaaaaat tcaaaatctt
      901 tcagagaagc tgttaaagga atttttaagt tcacagatat taacttagcg cgtgaggcta
      961 aaaatcgatt gattcatgat tatatcgatc aaccaaaata ttcaaaagct tgcgcatcat
     1021 tggatgatgg attcgaagac gcctttcaat ataccgtaca aggaaattcc cacaatcgac
     1081 taaagagtac caatctaatt gaacgactga atcaagaagt acgcagaaga gaaaagatta
     1141 ttcgcatctt ccccaatcaa acatcagcca atcgcttaat tggagccgtt cttatggacc
     1201 tacatgatga atggatttat tcttcaagaa aatacatcaa ttttgataag tagaaatggt
     1261 aaaaacattg tatag
//
LOCUS       DAYYEF010000162         1195 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000162 DAYYEF010000000
VERSION     DAYYEF010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.174"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1076
                     /locus_tag="ACHA1B_002928"
     CDS             <1..1076
                     /locus_tag="ACHA1B_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFM8703612.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DAYYEF010000163         1136 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000163 DAYYEF010000000
VERSION     DAYYEF010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1136
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.175"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..1061)
                     /locus_tag="ACHA1B_002929"
     CDS             complement(<1..1061)
                     /locus_tag="ACHA1B_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM8703613.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITE"
BASE COUNT          301 a          254 c          182 g          399 t
ORIGIN      
        1 tcttcggtta ttctttcttc ccaggatttt ggtcttaagg cctcattcag attgataaac
       61 agctttttta ctcgtttctg atactccttc atgacctttt tcattaatgt tttgattcta
      121 cgactataga ttccatagcg acgaatcgtt ttgaaattct tattttgaat atggcgaatc
      181 agtgcagcta tgaattcgtc tatactcatg gtcatcgtct ctttagtatt cgttcgtttg
      241 tccatgtagt tgaacatgac agtgtcgcca tcatacatta agattcggct taatgcgatc
      301 gggccacgct tcatataacg actgatgtat tggagtagtg actttagatt tgtcctgctc
      361 cttttaggag catttacgta aaacccttct ccattgttct tgtacgcagc ttgtaatctt
      421 gattgaactc tttgcttgtc ccactcacct aacgttcgtc taattagttt caatacagca
      481 tttttccagt attttcttaa catagaaaaa ggtaaataat cgtattcttc ccaacttcca
      541 tctcttgtta agccacccat agtaacaacc atatgaacat gcggattaaa ttctagtttt
      601 gatccaaagg tgtggattgt agctactata cctgccttca cctttctttt ctcaaaatag
      661 gcaagaataa tttttgcggc ttcatccatt agtcctttca gtaaggaatc tcgatagttt
      721 tccatcataa agatttcccg taacccctca tcgatcgtaa agattacgtg ccgatgtgtc
      781 actttaaaca tatcattcgc cacaaccgct gaccaccttt ggctttcacc tgttgcacac
      841 gttggacaga actttccacg acatttcaag ggaacaaact ttgtttgatg acatccctcg
      901 cagacaaaca gtcggtatcc tttttgaata tctccacaat atctaaactt gtttacttcc
      961 cgtttgacga ctagccgaat ctttcgcccg tatttctcaa caaagttatc ccaattatgg
     1021 tgttcgtcaa aaaagattgc ttcgagaata ttcgctttca tagtaatatt ttacttgttc
     1081 aaaaacaaaa tgaaaagggc taaaagactg gtagtgcagc ctttttagcc cttaac
//
LOCUS       DAYYEF010000164         1105 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000164 DAYYEF010000000
VERSION     DAYYEF010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1105
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.177"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1087
                     /locus_tag="ACHA1B_002930"
     CDS             <1..1087
                     /locus_tag="ACHA1B_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8703614.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT          402 a          192 c          214 g          297 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaa
//
LOCUS       DAYYEF010000165         1059 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000165 DAYYEF010000000
VERSION     DAYYEF010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.178"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(37..993)
                     /locus_tag="ACHA1B_002931"
     CDS             complement(37..993)
                     /locus_tag="ACHA1B_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703615.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgt
//
LOCUS       DAYYEF010000166         1044 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000166 DAYYEF010000000
VERSION     DAYYEF010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.179"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..209)
                     /locus_tag="ACHA1B_002932"
     CDS             complement(<1..209)
                     /locus_tag="ACHA1B_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0110001 - toxin-antitoxin complex
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0097351 - toxin sequestering activity
                     [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA];
                     GO_process: GO:0045927 - positive regulation of growth
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HFM8703616.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSD"
     gene            complement(308..622)
                     /locus_tag="ACHA1B_002933"
     CDS             complement(308..622)
                     /locus_tag="ACHA1B_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703617.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            complement(690..>1044)
                     /locus_tag="ACHA1B_002934"
     CDS             complement(690..>1044)
                     /locus_tag="ACHA1B_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703618.1"
                     /translation="DLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLIN
                     DTENPIRPQQWSIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIV
                     VRRENGYIVGLPFTL"
BASE COUNT          330 a          204 c          115 g          395 t
ORIGIN      
        1 aaatcagata cataagccca tgtacccgtt cgttgtaaat aaagttcttc ttgtaacaac
       61 tcccattttc tcttagaaat cataatgacg ccatcgttca atccattttt agaatcccta
      121 gtaatttcta tttcagaatt tgaatgaact acttcttgca acactttacc tatattttct
      181 ttgaagtttg ttggagtaat agtatccaaa atgaatacct ctcttctcta tacctctatt
      241 atgaagtgcc cataaaataa agcaagcgtt gaggaataat tctatcaaca cttgctttat
      301 taagctttca ttttgtagtt tgactaaaac caataatctt atttctaaac tctcgaaaaa
      361 cttcttgtgg ttgataatag tctggatcta tttcaaatgt ttgtgagaat aattcattga
      421 atttttctac tgaaataatg attttaccat tcttctctcg actgttttct attatttctg
      481 cttctaattc aaataaatct agtgacgaac taaaatcata aatcatgtca tattgaataa
      541 aaaaatcaag aaaaagttgc tcaaactctt ccttatttat cactaatgtt tcaaacggaa
      601 caactttatt ttcctcagcc attctcccag ttccattttc aaaaatcaca aaactgatat
      661 taccttaaaa actactaaca aaataaaact tataaagtaa atggcaaccc aactatgtaa
      721 ccattctctc tacgtactac gatttggtag tcctgccttt caatcggtaa ttcataatag
      781 taatttactg tttcttcttt gccactttca atatactctg gattatccaa tatcatatca
      841 tactcataaa gttcttcacc atccttattt tcaatcgacc attgttgtgg acgtatcgga
      901 ttttctgtat catttataag tgtataggtc acttgtaata cacgatcatg ttgtgcaaat
      961 tcatttcttt tttcggtcac ttcaatattt ttaaatgtta gttcaacccc atctgcctga
     1021 taagtttcac ctatttttaa atct
//
LOCUS       DAYYEF010000167         1037 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000167 DAYYEF010000000
VERSION     DAYYEF010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.180"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(20..91)
                     /locus_tag="ACHA1B_002935"
     tRNA            complement(20..91)
                     /locus_tag="ACHA1B_002935"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="ACHA1B_002936"
     tRNA            complement(113..200)
                     /locus_tag="ACHA1B_002936"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="ACHA1B_002937"
     tRNA            complement(225..298)
                     /locus_tag="ACHA1B_002937"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="ACHA1B_002938"
     tRNA            complement(312..382)
                     /locus_tag="ACHA1B_002938"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="ACHA1B_002939"
     tRNA            complement(384..459)
                     /locus_tag="ACHA1B_002939"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
     gene            complement(478..551)
                     /locus_tag="ACHA1B_002940"
     tRNA            complement(478..551)
                     /locus_tag="ACHA1B_002940"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(515..517),aa:Met,seq:cat)
     gene            complement(564..653)
                     /locus_tag="ACHA1B_002941"
     tRNA            complement(564..653)
                     /locus_tag="ACHA1B_002941"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(615..617),aa:Ser,seq:tga)
     gene            complement(677..750)
                     /locus_tag="ACHA1B_002942"
     tRNA            complement(677..750)
                     /locus_tag="ACHA1B_002942"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(714..716),aa:Ile,seq:cat)
     gene            complement(764..837)
                     /locus_tag="ACHA1B_002943"
     tRNA            complement(764..837)
                     /locus_tag="ACHA1B_002943"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(801..803),aa:Met,seq:cat)
     gene            complement(865..937)
                     /locus_tag="ACHA1B_002944"
     tRNA            complement(865..937)
                     /locus_tag="ACHA1B_002944"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(902..904),aa:Ala,seq:tgc)
     gene            complement(957..1030)
                     /locus_tag="ACHA1B_002945"
     tRNA            complement(957..1030)
                     /locus_tag="ACHA1B_002945"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(994..996),aa:Pro,seq:tgg)
BASE COUNT          281 a          285 c          246 g          225 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca gtgtttttag tttttaattg
      481 cgggagcagg atttgaacct acgaccttcg ggttatgagc ccgacgagct accagactgc
      541 tccatcccgc gataatatga aaaaggagga taagggattc gaacccttgc acggttttac
      601 ccgcctgacg gttttcaaga ccgttccctt cagccggact tgggtaatcc tccatatgaa
      661 acttacaacg ccacaatgga ccttgtagga ctcgaaccta cgaccggacg gttatgagcc
      721 gtctgctcta accaactgag ctaaaggtcc aggctcttaa aaatcgcggc ggaggggatc
      781 gaacccccga cctcccgggt atgaaccgga cgctctagcc agctgagcta caccgcgaaa
      841 aagatattca ttatttaaat gaaatggagc ctagcgggat cgaaccgctg acctcctgcg
      901 tgcaaagcag gcgctctccc agctgagcta aggccccgtg tttaaattta taattatcgg
      961 gaagacagga ttcgaacctg cgaccccttg gtcccaaacc aagtgctcta ccaagctgag
     1021 ctacttcccg tttaatt
//
LOCUS       DAYYEF010000168         1035 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000168 DAYYEF010000000
VERSION     DAYYEF010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.181"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>1035)
                     /locus_tag="ACHA1B_002946"
     rRNA            complement(<1..>1035)
                     /locus_tag="ACHA1B_002946"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          218 a          324 c          234 g          259 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatgcaccgc gggtccatcc atcagcgaca
     1021 cccgaaagcg ccttt
//
LOCUS       DAYYEF010000169         1002 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.182, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000169 DAYYEF010000000
VERSION     DAYYEF010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.182"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>1002
                     /locus_tag="ACHA1B_002947"
     CDS             <1..>1002
                     /locus_tag="ACHA1B_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HFM8703619.1"
                     /translation="GKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLVTP
                     FCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPRCL
                     LFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHYIV
                     TDMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQYR
                     QLKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQDL
                     LTAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLENLH
                     "
BASE COUNT          300 a          209 c          191 g          302 t
ORIGIN      
        1 ggcaagaaga tctctatgat tctcctgaat cgtagcggta ataaacggac ctatcttcgg
       61 ttgaagaaac agcgatacct ctgccgagca tgtaaaaaat attttaccgc tcggacgtat
      121 ctcgttaccc cattctgctt tatttctaag cagattcatt acaagatctt agaagaattg
      181 acagagcgtc aatctataaa agcaattggt aaacattgcg atgtttctgt gacaactgtt
      241 cagcggacat tgtccgcctt gtcatcagat atccgtcaga atcttgagta tttacctcgg
      301 tgtctattat tcgatgagtt tcgttctctt tctacatggc acggtaaatt ttctttttct
      361 tgtatggacg gtgagaccgg gaaactgttt gagatcttac ctagccgccg taaaaaagat
      421 ctcgttgctt ttttcatgcg tttttctctc aaagcgaggt tgggtgtaca ttacatcgta
      481 acggatatga acgctcctta tttctcacta gttaaagagt gttttccaaa tgcacaagtg
      541 atcgtcgatc ggtttcacat tgttcaacat ctgaaccgct tcttcgatgc ggttcgaaaa
      601 cgtgtgatga aaacacttga tcaaaaagac ccaatacaag ctaaacagta tcgccaattg
      661 aaatccttat tcaaattact tttaaaatca gaggatcgtt tagattacaa tacactaacg
      721 aaaagacgca atttcaattg gagactattg actgaaacag aagtagttga ccgccttcta
      781 aagatttctc ctgaacttaa aacagcttat cgttactacc aagacctgct tactgcgtat
      841 caggaaaaag atccagatac ttttttccag ctgcttcgag caatgcctgg agaagttcca
      901 ttggaactgc accatatcaa aaaagccttt ttcaaatacg agaaagggat tcggctggca
      961 ttactgaaga agtattcgaa tgcacgactg gaaaatctcc at
//
LOCUS       DAYYEF010000170         1000 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000170 DAYYEF010000000
VERSION     DAYYEF010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.183"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..434)
                     /locus_tag="ACHA1B_002948"
     CDS             complement(<1..434)
                     /locus_tag="ACHA1B_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703620.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
     gene            complement(451..855)
                     /gene="tnpA"
                     /locus_tag="ACHA1B_002949"
     CDS             complement(451..855)
                     /gene="tnpA"
                     /locus_tag="ACHA1B_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HFM8703621.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          304 a          172 c          163 g          361 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc accagttgtc agaagacaaa aacttttaga
      541 ccagaacatt tctttccaaa gaaattgttt gactcttgga aagtcacgtt ttatcaatct
      601 tgagctggca cttttatagg cattgatgaa ttttgtcaat tctgttttag gttgagcttt
      661 gaacataata tgaacgtggt ctttatcatg attccactcc actaaagtaa tgtgatacga
      721 ttctgaaatt ctttcaaaag tagttttggc ataatcagat atttcatcat caatcacttg
      781 tctacgatat ttcgttacta aaacaaggtg gtaataaaga agaaatactg aatgattatt
      841 tgtatctaat tccatgttat atcaactcat ttcttgtata gactgattgt aacatggaac
      901 aaaataaaaa ggcaatacgc cttagttgtc ggtcttcgag ttaccaacgg taaccctcat
      961 accgaacggc attcatcacc cacctataga ggatgggcga
//
LOCUS       DAYYEF010000171         1000 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000171 DAYYEF010000000
VERSION     DAYYEF010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.184"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(80..634)
                     /locus_tag="ACHA1B_002950"
     CDS             complement(80..634)
                     /locus_tag="ACHA1B_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8703622.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          324 a          185 c          107 g          384 t
ORIGIN      
        1 ttccgaaaat tcagttatct tcattaatct caccttctaa gttttcatta tacacaaaaa
       61 atatatccta atatctcaat tagcctccca atttaaaacc acgtaacgat gcccctattt
      121 catcttcagt tataccaatg tacctttttg taattgcttg cgagctatga ttaaaaataa
      181 acattaaggt agcaatgtct ctagttttct tgtagtagtg atacccaaaa gtttttctta
      241 atgtatgtgt tcctatatca tctcttccta atttttctgc tacatctgca tatatctgat
      301 agacacgatc ccttgttata tgtcgacctt gttgccgact tggaaataac caatcatttt
      361 cttctttacc ttcagtatat aataaaatct cttctctcaa attatctata aaaatcggtt
      421 ttcgcttacc tgttttatgt tcaacaataa taggcttact tttacctcgt atgtctccaa
      481 cttttaatcc tataatatct gacatacgta acccattatt gattccaaac aaaaataaaa
      541 aactatctct ttctggatta cttgttcttc ttagccaaaa ctgaaaatct tgtatctctt
      601 catttgtcct taacggttgt acattatagc tcactattgt ttcccttctt aaaaatattc
      661 tgagttcatg attatatata tattttacca taatcatgaa cttatatata tactctgtta
      721 aaagtgaaga aaatcaaggg gtttagttta tgattttata tcatttcagt aactcagaat
      781 attccgactt ttttgtacaa aaaaattaac cttacttata tgaagattct aagctcttat
      841 ttaaatttta gacgggcagt tatccgtaga agttcttaga atagctaatt tacataatta
      901 aattatatga aatttaagtt tgaacaatat actaagaact ccccttacta taaagtgaaa
      961 taaattagca tatgaataac cgtgctacca aacttttcat
//
LOCUS       DAYYEF010000172          943 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.186, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000172 DAYYEF010000000
VERSION     DAYYEF010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.186"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>943
                     /locus_tag="ACHA1B_002951"
     rRNA            <1..>943
                     /locus_tag="ACHA1B_002951"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DAYYEF010000173          904 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000173 DAYYEF010000000
VERSION     DAYYEF010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.188"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            430..>904
                     /locus_tag="ACHA1B_002952"
     CDS             430..>904
                     /locus_tag="ACHA1B_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFM8703623.1"
                     /translation="MTPIELRNYRKKLSSIHASGGGKKILSQKRFAQLLGCSVDYIKK
                     MEQGKKKIPEDFEKRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFLHSKRTVTENVLVQFSGQGCREYEEVMREQQ"
BASE COUNT          292 a          154 c          205 g          253 t
ORIGIN      
        1 gtcaatttat cgcgtttttt ctcctgaaaa atatagtgaa ataacaaaat tagatcattt
       61 aattttgtag ttattatcta tcgggagggc tctagacgta gtctggtagc cgcactctgc
      121 ctggcggtgc gcattaaggc tgcgaagcat gggcctataa tgcgcactcg ctagcagcgt
      181 gtgcagctca caaagaggtc gtgcgcttgc gcacggcctc tttgtgtaaa gccccccgat
      241 atataatatg gggggcagaa ataacataac acaaataaaa aagtgtattt aaatcagtta
      301 tatcaaggct ttagctaagg ttagaaggag tacccctttt tagaaaaatt agggggtacc
      361 acctgttata tcgggatttc tagcagatta aaaaaatcga aatttgttat tttataaagg
      421 agatagaata tgacaccgat tgaattgcga aattatcgaa aaaaattgag ttctattcac
      481 gcttcaggtg gagggaaaaa aatactctct caaaaacgtt ttgcacagtt attgggatgc
      541 tcggtagatt atataaagaa gatggaacaa gggaaaaaga aaatcccaga ggatttcgaa
      601 aaacgaatca aggaacgctt tcgattgtat atgaaaagcg gaatagatct tcgagcaatg
      661 atcgactatt tgcgtctctc cttttttggg acagactaca aaacagtgat tcaacgtgtg
      721 ctacgaatgg atctaacaga atttgaaaca cgtccgacgg gcttgtatct ttttgactgt
      781 ctttctgttc gtgggaatat ctgggtgttc ttgcattcaa aacgaaccgt aacagaaaat
      841 gtacttgtgc aattttcagg acaaggttgc cgggaatatg aggaagtcat gcgtgaacaa
      901 caaa
//
LOCUS       DAYYEF010000174          894 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000174 DAYYEF010000000
VERSION     DAYYEF010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..894
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.189"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..315
                     /locus_tag="ACHA1B_002953"
     CDS             <1..315
                     /locus_tag="ACHA1B_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703624.1"
                     /translation="FRLNRVPSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLN
                     GTTIEEVREYHRETLKLCIEKSNTQEKKILLEEEQKKERENERVRSHKESVQKLADEL
                     EF"
     gene            complement(312..>894)
                     /locus_tag="ACHA1B_002954"
     CDS             complement(312..>894)
                     /locus_tag="ACHA1B_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703625.1"
                     /translation="SIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQEVLDFV
                     RDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLDKFIKD
                     LIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLVYRSIV
                     QDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
BASE COUNT          282 a          152 c          169 g          291 t
ORIGIN      
        1 tttagattaa atagagtacc aagtcagctt tggaaagagt tgtttgttag aaattggaat
       61 tcaccaccac gatatacaac aatgcataga ccaggaattg cttctgttgt agacgatgaa
      121 attttactta atggaacaac tattgaggaa gtccgggaat atcatcggga aactttaaaa
      181 ctttgcattg aaaaaagtaa tactcaagaa aaaaaaatat tgctagagga ggaacaaaaa
      241 aaagagagag agaatgagcg agtcagatca cataaagaaa gtgttcagaa attagcagat
      301 gaattagagt tctagttgat agtcagttct ttcttaattc gatacacagt ttgtctagtt
      361 acattatagt ctgttgctat ttttgaaata gcaacaccat tctcctggtc ctgaacgatg
      421 cttctataaa caaggcgacg ttgaggatct tttgtgttcg cactgtataa cttaggacgt
      481 cctttataga cgccgtttgc tttagcaatc tttatccctt gtgcctggcg tcgttttgat
      541 tcagtacgct cttgttcagc aatcatggcc aagatttgaa tgattaggtc tttgataaat
      601 ttatccagga gaggatttcc gattgcttca gccatgatcg gtaaattagt gataataagt
      661 cgcacatttt tcttctttag ataatttact gaatcgataa tctcgtcata attacgtcca
      721 agtcgatcga tagcctctac aataaaaata tcttggtctc taacaaaatc tagaacttcc
      781 tgaaaaatcg gtcgatgagt aatagtcgct ccagattgtt tctcgatgaa aattttttca
      841 gcaccaaatt ttctcatttc ctcgatttga cgttgttcat tttgatcgat cgat
//
LOCUS       DAYYEF010000175          822 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.190, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000175 DAYYEF010000000
VERSION     DAYYEF010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..822
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.190"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..693
                     /locus_tag="ACHA1B_002955"
     CDS             <1..693
                     /locus_tag="ACHA1B_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFM8703626.1"
                     /translation="ATISRHSSGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILS
                     DGQKIDNNKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEK
                     VMNQRTDFLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYK
                     ADWYGRKIIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINIL
                     TEGLRLHSMGLA"
BASE COUNT          302 a          131 c          151 g          238 t
ORIGIN      
        1 gctacaatat cacgtcattc tagcggtaaa tactatattt ctttgttgtg taaagaagaa
       61 attatcgaat tacctaaaac taattccaca attggtattg acttaggtat tatggacttt
      121 gcgattcttt ctgatggaca aaaaattgat aataataaat tcacgtccaa aatggaaaag
      181 aaactaaagc gtgaacaacg caaattgtct aggcgtgctt tattggctaa aaataaaggt
      241 accaatctat ttgaagctaa aaattatcaa aaacaaaaac gcaaagtagc tagattgcat
      301 gaaaaagtaa tgaatcaacg tactgatttt ctgaataagt tgagtacaga aatgatcaaa
      361 aatcacgata ttatctgtat tgaagactta aacacaaaag gtatgttgcg aaatcataaa
      421 ttagctaaaa gtatttctga tgtttcttgg tcaaagtttg tgactaaatt acaatacaag
      481 gctgactggt atggacgaaa aatcatcaaa gtagataaat ggtttccgtc tagtcagatt
      541 tgttcagagt gcggacataa agatggcaag aaatctcttg aaattcgaga atggacttgt
      601 cctgtttgtc atactcatca tgatcgtgat atcaatgcta gtatcaatat tctgaccgaa
      661 ggtctaagac tacattctat gggattggct tagatccaat catcaagaac cgtaggaact
      721 acggggatag cttggtaaat aagagacacc gctgttagta aagaaatacg ctatcaagta
      781 tgctctattc ccaagaagct cccacttcaa gcgttaagaa cc
//
LOCUS       DAYYEF010000176          793 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000176 DAYYEF010000000
VERSION     DAYYEF010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..793
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.191"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..782
                     /locus_tag="ACHA1B_002956"
     CDS             <1..782
                     /locus_tag="ACHA1B_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8703627.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          244 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc ttt
//
LOCUS       DAYYEF010000177          785 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000177 DAYYEF010000000
VERSION     DAYYEF010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..785
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.192"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..714
                     /locus_tag="ACHA1B_002957"
     CDS             <1..714
                     /locus_tag="ACHA1B_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HFM8703628.1"
                     /translation="KKRILVTIGLAFLLAGCTNGNESKKESTKETAKATVATTTTTST
                     ESKSTAASTETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADK
                     SAQLEAFMTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWS
                     ESGTGQADYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNE
                     TANNELKNGFNQIVYGQAN"
BASE COUNT          282 a          151 c          158 g          194 t
ORIGIN      
        1 aaaaaaagga ttttagtaac aattggtcta gcttttttgt tagctggttg taccaacggg
       61 aatgaatcga aaaaagaatc aacaaaagaa acagcgaaag caacagttgc aactactaca
      121 acaactagca cagagagcaa gtcaactgca gcaagtacag aaacagcaga tacctctact
      181 tcgtcagagt cttccaaaac gactgaaaca actcaaacat ctacttcaag ttcttctgta
      241 gaggcttcat cttcctcttc agaaagcagc gaacaagttg aacaaacact gtggaatgca
      301 gacaaatccg cacaattaga ggcatttatg accaaatggg gccaaacaat gggacaacaa
      361 tacaaaagtt atacgaatca aatgagtgtg gacttatatg gtcttaaagt ccctcaagct
      421 attttgaacg gggagtggaa gatggctatt ggtggagtgc ctgtttctgc agaatggtca
      481 gaaagtggga caggtcaagc agactatcaa atcacagccg tctattccga tgcagagaca
      541 gaaccatatc tgaaaaagca cgtctatcta ttcgggtttc agcaaaatca gccaaaagta
      601 ttggtgacac aacaaaatca ggggaatccc gataattatc tttacttcaa cgagacagcg
      661 aataatgaat tgaaaaatgg ctttaatcaa atcgtttatg gacaagcaaa ttaatgagat
      721 aaacaagggg ttgtgacatg tcttttatca caaccccttg ctcagtttat ttgttagtct
      781 tttat
//
LOCUS       DAYYEF010000178          765 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000178 DAYYEF010000000
VERSION     DAYYEF010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.193"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            660..>765
                     /locus_tag="ACHA1B_002958"
     rRNA            660..>765
                     /locus_tag="ACHA1B_002958"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          315 a          124 c          134 g          192 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactctc gatgaagtag acctttgaaa actgaacaaa
      541 gtaagacaaa ccaaatgtgt agggcgtctt gattcaattc aagacaacaa acatttttaa
      601 caagcaagca atatgctagc aaacaaattg agcttaacaa tcgcaagatt gttcgaactt
      661 tttatgagag tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag
      721 tcgaacgctt ctttttccac cggagcttgc tccaccggaa aaaga
//
LOCUS       DAYYEF010000179          748 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000179 DAYYEF010000000
VERSION     DAYYEF010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.194"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..746)
                     /locus_tag="ACHA1B_002959"
     CDS             complement(<1..746)
                     /locus_tag="ACHA1B_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HFM8703629.1"
                     /translation="MLTALFLLPINGFAYTINNEFNLGANEGSSQVANNQYILLHETA
                     NETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIE
                     LQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHT
                     DPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAH
                     IDQFGEIENANLHVAGWHIANYKYEYIFIM"
BASE COUNT          204 a          155 c          142 g          247 t
ORIGIN      
        1 tccataatga agatatactc gtatttatag ttagcaatgt gccatccagc tacatgcaaa
       61 tttgcatttt cgatttctcc aaactgatca atgtgggcgt aattcgttcc atctgtcagt
      121 gtaggattag ctgcaccagc tcgtgttgga tcaatgacag gcttgttttc agaagttgtt
      181 ggattttcat cggtaaatcc atgagctaaa tcatatgcta atttttcttt acttacgccc
      241 atttcagaaa gataaccgta aggatctgta tgatcgcccc agatgttttg tgttacccat
      301 aaatgcgatt tgattcccgg ttggttataa ggagtgtcca acgttaatgg aataccatat
      361 ttcattgctg aatctctagc caattcaacg tatgccttgt agtttttctc aaacgttgct
      421 ttatcatgtg tgtgttgtaa ctcaatctgc acaggactgt tggcattagc atacgaacca
      481 gcaccgtact gtacataacc aggttgaccg acttgataaa caattccgcc gtctcccaca
      541 atataagcag tataagcgct agtccatgaa cgttgcatat actgcgcttc attgcgtcct
      601 gttgctgttt cattagccgt ttcatgcagt aaaatatact gattatttgc tacttgtgag
      661 ctaccttcat ttgcgcccaa attaaattca ttgttgatag tataggcaaa tccgttaatt
      721 ggcaataaaa aaagagccgt taacaggc
//
LOCUS       DAYYEF010000180          711 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000180 DAYYEF010000000
VERSION     DAYYEF010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.195"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..375
                     /locus_tag="ACHA1B_002960"
     CDS             <1..375
                     /locus_tag="ACHA1B_002960"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8703630.1"
                     /translation="DDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCYTLLRPD
                     GKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRACHVYEK
                     LGGKNDYKDEIVYVYDYEKGDK"
     gene            376..>711
                     /locus_tag="ACHA1B_002961"
     CDS             376..>711
                     /locus_tag="ACHA1B_002961"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8703631.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGI"
BASE COUNT          285 a           53 c          125 g          248 t
ORIGIN      
        1 gatgataata tggtttttga tattgataat ttaaaaggat ttcttaatga taccagttca
       61 tttgggttta tagctaaaga aaataataaa attataggat ttgcatattg ctatacactt
      121 ttaagacctg atggaaaaac aatgttttat ttacactcaa taggaatgtt acctaactat
      181 caagacaaag gttatggttc aaaattatta tcttttatta aggaatattc taaagagatt
      241 ggttgttctg aaatgttttt aataactgat aaaggtaatc ctagagcttg ccatgtatat
      301 gaaaaattag gtggtaaaaa tgattataaa gatgaaatag tatatgtata tgattatgaa
      361 aaaggtgata aataaatgaa tatagttgaa aatgaaatat gtataagaac tttaatagat
      421 gatgattttc ctttgatgtt aaaatggtta actgatgaaa gagtattaga attttatgat
      481 ggtagagata aaaaatatac attagaatca ttaaaaaaac attatacaga gccttgggaa
      541 gatgaagttt ttagagtaat tattgaatat aacaatgttc ctattggata tggacaaata
      601 tataaaatgt atgatgagtt atatactgat tatcattatc caaaaactga tgagatagtc
      661 tatggtatgg atcaatttat aggagagcca aattattgga gtaaaggaat t
//
LOCUS       DAYYEF010000181          694 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000181 DAYYEF010000000
VERSION     DAYYEF010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.196"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(52..627)
                     /locus_tag="ACHA1B_002962"
     CDS             complement(52..627)
                     /locus_tag="ACHA1B_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytS/YhcK type 5TM receptor domain-containing
                     protein"
                     /protein_id="HFM8703632.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          228 a          151 c          124 g          191 t
ORIGIN      
        1 tgaaaaaaca gagccagatt agcattattt tgctaatcca gctctgttta ttcagcctat
       61 ttttcttttt gaatatatca agcgttgggg caacatagtg atgactaatg aaacaacgac
      121 gatagacaac aagcgatcaa ggtagtctgt acccgcctgt accaagatca cacttgttgt
      181 ctgacttaaa cctaacccat gtaatagctg aacgatcata ctggatcctg aggaggtgat
      241 cccgccaaat aactgaacgg taatgatcga agaaacgatc gttccaggta ccgacaaaat
      301 caaagcgagt aataacagtt tcaagctgtt tttatctttg ccgagatatc ttggcaaaat
      361 caatccagca agcaagcctg tgagaatttg gattggcgaa taatacagag aaaaaatatc
      421 tgtagtcact ccacttaaaa taccgctgga caatcctgtc agcattccag gtacaggccc
      481 aagcaatgca ccagcaaaaa tcgttccgat agaatcgaga tagattggca aacgaagcca
      541 taaagcaatc gttcctccaa tataattgat cccaatacac aaagccatca ctgtaagtac
      601 gcgagttgcc attttgtttt tattcatttt gttagcccat ctttaacctt tccaaatctt
      661 tcataatcgt ttcttcttgt gcatttaaaa gaac
//
LOCUS       DAYYEF010000182          692 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000182 DAYYEF010000000
VERSION     DAYYEF010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.197"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>692
                     /locus_tag="ACHA1B_002963"
     CDS             <1..>692
                     /locus_tag="ACHA1B_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="HFM8703633.1"
                     /translation="ATISRHSSGKYYISLLCKEEVRELPKSNSAVGIDLGIIDFAILS
                     TGQKFDNNKFTSKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEK
                     VMNQRTDFLNKLSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYK
                     ADWYGRKIIKVDKWFPSSQICSNCGHKDGKKSLEIREWTCPICHTHHDRDINASINIL
                     TEGLRLHSMGLA"
BASE COUNT          247 a          118 c          124 g          203 t
ORIGIN      
        1 gctacaatat cacgtcattc tagcggtaaa tattatattt ctttgttatg caaagaagaa
       61 gttcgcgaac tacctaaatc taattctgct gttggtattg acctaggtat tatagacttt
      121 gcaattcttt ctaccggtca aaaatttgat aataataaat ttacgtccaa aatggaaaag
      181 aaactcaaac gtgaacaacg taagttgtca agacgtgcct tattagctaa acaaaaaggt
      241 atcaatctgt ttgaagctag aaattatcaa acacaaaaac gtaaagtagc acgattgcat
      301 gaaaaagtaa tgaatcaacg tactgatttt ctgaataagt tgagtacaga aattatcaaa
      361 aatcacgata tcatctgtat tgaagactta aacacaaaag gcatgttgcg taatcataaa
      421 ctagcaaaaa gtatttcgga tgtttcttgg tctagttttg tgtctaaatt acaatacaag
      481 gctgactggt acggtcggaa aatcatcaaa gtagataagt ggtttccatc tagccaaatc
      541 tgttcgaatt gtggacataa agacggcaag aaatctctcg aaattcgaga atggacttgc
      601 cctatttgtc atactcatca tgaccgagat atcaacgcta gtatcaatat cctgaccgaa
      661 ggtctaaggc tacactctat gggattggct ta
//
LOCUS       DAYYEF010000183          691 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000183 DAYYEF010000000
VERSION     DAYYEF010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..691
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.198"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            10..>691
                     /locus_tag="ACHA1B_002964"
     CDS             10..>691
                     /locus_tag="ACHA1B_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HFM8703634.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGER"
BASE COUNT          228 a          125 c          147 g          191 t
ORIGIN      
        1 tgaaaacgaa tgcaaggagt gatagctatg atgtctaaaa acaatacgaa tggtagaaat
       61 caatttgcga tgcttacgat tgatgatcta gttcctcaag atcatctcgt tcgaaagatt
      121 gatgccgcgc ttgattttga atttatttat ccaatcgtcg aagccactta ctccgattta
      181 ggtcgcccaa gtatcgatcc agtgattctg atcaaattgg tgtttattca gtatttattc
      241 ggtatccgtt ccatgcgaca aaccattaag gaagtcgata ccaatgtcgc ttaccgctgg
      301 tttttaggct actccttcga ggagaaaatc ccccatttct caacttttgg aaagaattat
      361 gttcgccgat ttagagaaac gacggtgttt gaggatattt ttgcctatat tttagaacaa
      421 gcagttaaag caggttttgt aacagaggat aatttgtatc tggattctac ccacatcaaa
      481 gctaacgcca ataaacataa gtttacgaaa gaaatgaccc atgatgaagc gaaagcctat
      541 caggatgaat tagaagatga gatcaatcgt caacgaatag aggctggaaa acgccctttt
      601 actttggact tagaaaagga agtgaagctg aaagaaagaa aaataagtaa agctgatccg
      661 gaaagcggct actacgtcaa aggcgaacga g
//
LOCUS       DAYYEF010000184          631 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000184 DAYYEF010000000
VERSION     DAYYEF010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.199"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            157..>631
                     /locus_tag="ACHA1B_002965"
     CDS             157..>631
                     /locus_tag="ACHA1B_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HFM8703635.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQ"
BASE COUNT          223 a           93 c          139 g          176 t
ORIGIN      
        1 agaaaaaagt tttataaacc cttttgtatc aagtgattat ctaaggtcag cagttgtact
       61 acttttccca aaaaacgagg gggactagtt gatatatcgg tgtttctaaa gggttaaaaa
      121 aaatcgattt tgttatttta taaaaggagc gagaaaatga caccgattga gctaaaaagc
      181 tacagaaaga agttaagtgc aattcataat ataagtggag ataaaaagcc gctatcacaa
      241 gcaagatttg cgcaattgat gggctgctca aaagattaca ttagaaagat ggaacaaggg
      301 aaaagaaaaa tcccagagga ttttgaacaa cgaatcaagg aacgctttcg attgtatatg
      361 aaaagcggaa tagatcttcg agcaatgatt gattatttgc gtctttcctt ttttgggaca
      421 gactacaaaa cagtgattca acgtgtatta cgaatggatc tgacagaatt tgaaacacgt
      481 ccaacgggct tgtatctttt tgactgtctt tctgttcgtg ggaatatctg ggtgttctgg
      541 cattcaaaac gaactgtaac agaaaatgta cttgtgcaat tttcaggaca aggttgccgg
      601 gaatatgagg aagtcatgcg tgaacaacaa a
//
LOCUS       DAYYEF010000185          623 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000185 DAYYEF010000000
VERSION     DAYYEF010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.200"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>623)
                     /locus_tag="ACHA1B_002966"
     CDS             complement(<1..>623)
                     /locus_tag="ACHA1B_002966"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_process: GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase family
                     protein"
                     /protein_id="HFM8703636.1"
                     /translation="AIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPE
                     IYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDL
                     TDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIID
                     EYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYY"
BASE COUNT          214 a          104 c           44 g          261 t
ORIGIN      
        1 ataatattct tcaactatat cttgatattc ttttgctttc tcaatatcta tatttccata
       61 cattcttaat atatcttctc caaaatttgt tcctatttct tcttcactat cttcaagtaa
      121 gtatataaaa tcacaatatt catctataat tccagaatct ccaaaatcaa ttattccagt
      181 taatctatta ttgccatcta acaatagatg attacaacta aaatcattat ggcataaaca
      241 ctttttaccc tcaaaaactg ttgttgcatt tagtctttcc ataaaacttt ctatataatc
      301 tttttctata tcagttaaat cattataaat agtttcacgc aacaatatat actcttctaa
      361 tacattttgt ttattatcaa tagtacattc actaatatct gtataatcta aaccgtgcat
      421 ttgtcttaaa aaactggcaa tatctcgttt taacaaattt tgttcttctt ctgacatagt
      481 agaataaatt tctggtgtta aaaaagttcc tttaatttct ttataaccta gtatagataa
      541 ttcatcacta atatacgaat attcaatatt aggaattttt acattagttt ctaaatttgt
      601 atttaaaaaa ttatatattg ctt
//
LOCUS       DAYYEF010000186          611 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000186 DAYYEF010000000
VERSION     DAYYEF010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.201"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>611
                     /locus_tag="ACHA1B_002967"
     CDS             <1..>611
                     /locus_tag="ACHA1B_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HFM8703637.1"
                     /translation="ATHKPTGLKEVNPLTKVTITDAVKYHDLVVGKTYTVNGVLMDKV
                     TEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILDARALRGKEVVVFEDLFREGVLLAS
                     HADITDNDQTIKISNPTITTKATNKNGGKEILALPNQTVLEWVKVDGLAIGQIYRLIV
                     QGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFLVDGRNLAGKG"
BASE COUNT          206 a          120 c          139 g          146 t
ORIGIN      
        1 gctacacata aacccactgg cttgaaagag gttaatccat taacgaaagt caccattaca
       61 gacgctgtga aataccacga tttggtcgtt ggaaaaacat acacagtcaa cggtgttcta
      121 atggacaaag taacggaaaa accagtgcta gtagatggaa aagaagtcac aagtacctta
      181 acgtttgtgg cagaaacaac ggatggtaca gtcaatctag actttattct agacgcacgt
      241 gcgttgcgag gcaaagaagt cgtggtcttt gaagatctgt ttagagaagg cgtattattg
      301 gcttctcacg cagatattac cgacaatgac caaaccatca aaatcagtaa tccaaccatt
      361 acgacgaaag cgacgaataa aaatggcgga aaagagatct tggccttgcc aaatcaaact
      421 gtgcttgaat gggtcaaagt agacggtctt gcgattggtc aaatctatcg cttaattgtt
      481 caaggctact taacaccaga cggcacacca tttgaaggca ctcatgcgga aaaagtcttt
      541 gcggccgata aagaaatgat ggaattctta tttgaattct tagtggacgg tcgcaatctt
      601 gcaggaaaag g
//
LOCUS       DAYYEF010000187          588 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000187 DAYYEF010000000
VERSION     DAYYEF010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.202"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(65..150)
                     /locus_tag="ACHA1B_002968"
     tRNA            complement(65..150)
                     /locus_tag="ACHA1B_002968"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Leu,seq:taa)
     gene            complement(167..238)
                     /locus_tag="ACHA1B_002969"
     tRNA            complement(167..238)
                     /locus_tag="ACHA1B_002969"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Gly,seq:gcc)
     gene            complement(250..322)
                     /locus_tag="ACHA1B_002970"
     tRNA            complement(250..322)
                     /locus_tag="ACHA1B_002970"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Thr,seq:tgt)
     gene            complement(340..421)
                     /locus_tag="ACHA1B_002971"
     tRNA            complement(340..421)
                     /locus_tag="ACHA1B_002971"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(385..387),aa:Leu,seq:tag)
     gene            complement(429..501)
                     /locus_tag="ACHA1B_002972"
     tRNA            complement(429..501)
                     /locus_tag="ACHA1B_002972"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(466..468),aa:Lys,seq:ttt)
     gene            complement(505..577)
                     /locus_tag="ACHA1B_002973"
     tRNA            complement(505..577)
                     /locus_tag="ACHA1B_002973"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(542..544),aa:Val,seq:tac)
BASE COUNT          149 a          169 c          138 g          132 t
ORIGIN      
        1 cccctaacct tttgatccgt agtcaaacac tctatccagt tgagctatgg gcgcatattt
       61 gaaatgccga ggaccggaat cgaaccggta cggtgatcac tcaccgcagg attttaagtc
      121 ctgtgcgtct gccagttccg ccaccccggc gcgattgctt tggcaaagcg gaaaacgggg
      181 ttcgaacccg cgacccccac cttggcaagg tggtgctcta ccactgagct atttccgcgt
      241 gtttaaagat gccggctaaa ggacttgaac cctcgaccct ctgattacaa atcagatgct
      301 ctaccaactg agctaagccg gcatgtaaaa cttaaattat gcgggtgaag ggacttgaac
      361 ccccacgccg taaggcgcta gatcctaaat ctagtgcgtc tgccaattcc gccacacccg
      421 caaaaatatg agccgtacag ggctcgaacc tgtgaccctc tgattaaaag tcagatgctc
      481 taccaactga gctaacggct catatggagg ttaacgggat cgaaccgctg accctctgct
      541 tgtaaggcag atgctctccc agctgagcta aacctccatg gataactt
//
LOCUS       DAYYEF010000188          588 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000188 DAYYEF010000000
VERSION     DAYYEF010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.203"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            411..>588
                     /locus_tag="ACHA1B_002974"
     CDS             411..>588
                     /locus_tag="ACHA1B_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM8703638.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTSGSFKEKDN"
BASE COUNT          200 a           98 c          104 g          186 t
ORIGIN      
        1 tttatcacgg atgagcttga aatcgtcttt tatacgtatc aaattgaaat gttcggcata
       61 caacctatcg ttgttactac attactaatt gtcacttgtt aaggaacttg gatcctttct
      121 aaacattccc tagagataaa ttttacttta tccctccgtt aatatccaat ttaagcacct
      181 ttccgattca gggttaattt gcatatcaag tgcagcttgt gttctagtaa gattagccct
      241 tttagtccgg ctgagttgac ttatggatat aagatatggt catagcaaat agatactacg
      301 tatagtctgt taatttagtg tcattaatct taagttggat aggctacaat taactagaca
      361 gaaaaattaa ggtgtgtaga ctagaagaaa acataccagg aggaattttt atgtctaaga
      421 gaacacgaag aactttttca caagaattca agcaacaaat cgtcaatctt tacttagctg
      481 gaaagccacg tgtagaaatc attcgagaat atgaactaac ggcttcagca tttgacaaat
      541 gggtaaagca atctaaaacg agtggttcat tcaaagaaaa agataatc
//
LOCUS       DAYYEF010000189          574 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000189 DAYYEF010000000
VERSION     DAYYEF010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.204"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..572
                     /locus_tag="ACHA1B_002975"
     CDS             <1..572
                     /locus_tag="ACHA1B_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HFM8703639.1"
                     /translation="IRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIK
                     GRKIYLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQY
                     QMPQYQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLN
                     EYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          248 a           71 c           94 g          161 t
ORIGIN      
        1 aaatccgaat aaagcgatat aaatcttata aaggaacagt aggaaaaatt gccaagaatg
       61 tgttaaaacg aaatttttca gtagatacac ccaataaaaa atgggtgaca gacgtcactg
      121 aattcaagat aaaaggaaga aaaatctatc tatctcctat acttgattta tttaacggag
      181 aaataattag ttatagtata tcaactagtc caacatataa actgattgaa gaaatgcttc
      241 aacaagcaat taaaaaaaag ggaactgagg gttcactgat tctacattca gatcaaggat
      301 ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga gaataacatt attcaaagca
      361 tgtctagaaa aggaaattgc ttagataatt ctgtaataga aaattttttt ggtgtgctta
      421 aatcagagtt tttttatcga gaaaaattcc gatcaattga gatatttcaa agtaaattaa
      481 atgagtatat taggtggtat aataacaaaa ggataaaact aaagttaaat ggactatctc
      541 cagtagaata tcggaaacag tccattaaat agtt
//
LOCUS       DAYYEF010000190          519 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000190 DAYYEF010000000
VERSION     DAYYEF010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.205"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            23..>519
                     /locus_tag="ACHA1B_002976"
     CDS             23..>519
                     /locus_tag="ACHA1B_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HFM8703640.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          189 a           95 c           86 g          149 t
ORIGIN      
        1 tcacagaaaa gaggacttcc ctatgaatga ttttactaca gaaattgtgc aaactctagt
       61 cactaaaggc gatttaaatg aattattccg ttcgcactta gaaaaagcga taaacacact
      121 cctacggact gaattaacgg cttttttaga ttacgaaaaa tatgatcgca ctggttttaa
      181 ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat atggtgaatt
      241 aacattggaa atacctagag atcgtaatgg tgagtttaaa caacaaactt taccagccta
      301 caaaagaaca aacgatacat tggaaaccac tattatccat ttattcgaaa aaggtgttac
      361 gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt catcactata ctccacaaac
      421 catgtccaac atgactaaag ttctgactga agaagtaaat gcctttaaat ccagagcctt
      481 aaatgataag tatgtcgcta tttttatgga cgctactta
//
LOCUS       DAYYEF010000191          505 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000191 DAYYEF010000000
VERSION     DAYYEF010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.206"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>505
                     /locus_tag="ACHA1B_002977"
     CDS             <1..>505
                     /locus_tag="ACHA1B_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703641.1"
                     /translation="QDIEERKNAMHGQAKSAEELINQKRHEAKYTPEAMNREEIMLRK
                     RVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKENPQNSTSSHGGRSVDVRENIQ
                     GSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSSSTSQPKTVDVRENVQNSTSS
                     QGFKSVDV"
BASE COUNT          204 a           74 c          114 g          113 t
ORIGIN      
        1 caagatattg aagaacgtaa aaatgctatg cacggtcaag ctaagtctgc tgaagaatta
       61 attaatcaga agcgtcatga agcgaaatac acgcctgaag caatgaatcg cgaggaaata
      121 atgttaagga aacgtgtaga agggcggaca ggcgctaata ttgacggaaa agaagcgttg
      181 accaaagaaa gaattcaaga agctaaaaat tcaaatacag gattagaaaa attagtcaaa
      241 gaaaatccac aaaattctac aagtagtcat ggtggccgat cagtagatgt ccgagaaaat
      301 attcaaggtt cactgaatgg tcatgttgga cggaatgttg atgtaagaga gaatttacaa
      361 agttcttcaa atgctcaagg tactaagaca attgatgttc gagaaaatct gcaaagtagc
      421 agtacaagtc aaccaaaaac agtagatgtt cgagaaaatg tacaaaattc tacaagtagt
      481 caagggttta aatcagtgga tgtcc
//
LOCUS       DAYYEF010000192          481 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000192 DAYYEF010000000
VERSION     DAYYEF010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.207"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>481
                     /locus_tag="ACHA1B_002978"
     CDS             <1..>481
                     /locus_tag="ACHA1B_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA];
                     GO_process: GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=2
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HFM8703642.1"
                     /translation="FPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSP
                     LCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVK
                     VLETLSEEANLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQ
                     "
BASE COUNT          172 a           95 c           78 g          136 t
ORIGIN      
        1 ctttcctagt aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat
       61 tattcgatac tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag
      121 ttttcctagt ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat
      181 agccaaagtt ggctataact caacaaaaaa atcttatttt tatggtctta aaattcatat
      241 gatcgttact aagactggct ttccgattac ttactcaatc acgaatccag gtgtccatga
      301 cgtgaaagtg ttagagactt tatcggaaga agcgaatctt cccaatatcc taggggacaa
      361 aggatatatt agccataaaa tccatgaaaa gcttgccctt aagggcatta ctatatccgt
      421 tccgccacgt aaaaacatgg ataaatcaga aaaactagac cacagcttac ttggaaaaca
      481 a
//
LOCUS       DAYYEF010000193          470 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000193 DAYYEF010000000
VERSION     DAYYEF010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.208"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..324
                     /locus_tag="ACHA1B_002979"
     CDS             <1..324
                     /locus_tag="ACHA1B_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703643.1"
                     /translation="RENVQSSTSSQGFKTVDVRENIQKDSGEMKEKTQKINIVEDRKS
                     AKKFDSNHETVIIDSEIRENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLRNKRG
                     GLSCN"
BASE COUNT          209 a           56 c           89 g          116 t
ORIGIN      
        1 cgagaaaatg tacaaagttc tacaagtagt caaggattca aaacagtaga tgttcgggag
       61 aacattcaaa aagatagtgg agaaatgaaa gaaaaaacac aaaaaatcaa tatcgttgaa
      121 gacagaaagt cagcgaaaaa atttgattca aatcatgaaa cagtgattat tgatagtgaa
      181 atccgtgaaa atgataaggg atcaaaatca agacgaagat tcacttatga agacaatgag
      241 ttattcagag atacacttaa tgatcctaat ccacttttcg ataatttatt aagaaataaa
      301 agggggggat tgtcatgcaa ttaattctaa agattagtac gcatgatttc ttagaacttg
      361 acgaattatg tgaatcagta aagaacgcaa caaatgaaaa aatcacggtc actaattata
      421 ttgaactgat gattcaagaa gaattaaaga tgaaaaatga aatagagagc
//
LOCUS       DAYYEF010000194          469 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000194 DAYYEF010000000
VERSION     DAYYEF010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.209"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..300
                     /locus_tag="ACHA1B_002980"
     CDS             <1..300
                     /locus_tag="ACHA1B_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703644.1"
                     /translation="RENVQSSTSSQGFKTVDVRENVQKDSGEMKEKTQKINIVEDRKS
                     AKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNELFRDTLNDPNPLFDSLLKK"
BASE COUNT          208 a           59 c           87 g          115 t
ORIGIN      
        1 cgagaaaatg tacaaagttc tacaagtagt caaggattca aaacagtaga tgttcgggag
       61 aacgttcaaa aagatagtgg agaaatgaaa gaaaaaacac aaaaaatcaa tatcgttgaa
      121 gacagaaagt cagcgaaaaa atttgattca aatcatgaaa cagtgattat tgatagtgaa
      181 atccgtgaaa atgataaggg atcaaaacca agacgaaggt ttacctatga agacaacgag
      241 ttattcagag atacacttaa tgatcctaat ccacttttcg atagtttact taaaaaataa
      301 agaggtgatt gtcatgcaat taattctaca gattagtaca catgatttct tagaacttga
      361 cgaattatgt gaatcagtaa agaaagcaac aaatgaaaaa atcacggtca ctaattatat
      421 tgaactgatg attcaagaag aattaaagat gaaaaatgaa atagagagc
//
LOCUS       DAYYEF010000195          462 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000195 DAYYEF010000000
VERSION     DAYYEF010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.210"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..430)
                     /locus_tag="ACHA1B_002981"
     CDS             complement(<1..430)
                     /locus_tag="ACHA1B_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HFM8703645.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          132 a           92 c           59 g          179 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DAYYEF010000196          445 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000196 DAYYEF010000000
VERSION     DAYYEF010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..445
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.211"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>445
                     /locus_tag="ACHA1B_002982"
     CDS             <1..>445
                     /locus_tag="ACHA1B_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703646.1"
                     /translation="KIDSFLVYHTSAMKNLTQNLLKKDNSSILKIELKKENNKSMKIS
                     KKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLSRIKGLSSIFEGPINYTTFNN
                     YGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLLNICTILIS"
BASE COUNT          165 a           55 c           54 g          171 t
ORIGIN      
        1 aaaattgatt cttttctagt atatcatact agtgctatga aaaatttaac gcaaaactta
       61 ttaaaaaaag acaattctag tatactgaaa atagaattaa aaaaggagaa caacaaatct
      121 atgaaaataa gtaaaaaagc atttctttta gtagttctta tcttacttag tactttatat
      181 tcagtaaatt ttatgagaaa tgctcaagaa atttatacaa caggtgattt atcttttcat
      241 ctttcacgaa tcaaagggtt atcttctatt tttgaagggc caatcaacta tacaacattt
      301 aacaattatg gagatggact gaactatttt tatccttttc ttacaataat tcctgcagtc
      361 gttttttatg gaatttcaaa taacttaata ttaagttatg ttctatatat ttggttatta
      421 aatatttgta cgattctgat tagtt
//
LOCUS       DAYYEF010000197          427 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.212, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000197 DAYYEF010000000
VERSION     DAYYEF010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.212"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            76..>427
                     /locus_tag="ACHA1B_002983"
     CDS             76..>427
                     /locus_tag="ACHA1B_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HFM8703647.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIF"
BASE COUNT          164 a           68 c           80 g          115 t
ORIGIN      
        1 agaaaaataa aaaggcattt atggtacact caaattgtat ttccgacgaa agaaaacaaa
       61 ggagtgtaac cataaatgac ctacaaacat cttaccatag acgaactgac aatgatagaa
      121 tcatattatc ttcaacataa taagccggtt gaaatcgcta accgaatggg acgtgctata
      181 caaactattt ataatgtagt caataagttc aagcaaggca agactgctct tgattattgg
      241 caccagtata aagaaaataa gaaaaaatgt ggtagaaaag tcattcaatt acctgctcat
      301 gaagtagatt acattaaaga gaaagtcact cttggttgga cgcctgacgt cattatcggg
      361 cgaaaagaaa ggtctgtttc atgcggtatg agaacacttt atcgtttatt ttctaaagga
      421 atatttg
//
LOCUS       DAYYEF010000198          420 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000198 DAYYEF010000000
VERSION     DAYYEF010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..420
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.213"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..216
                     /locus_tag="ACHA1B_002984"
     CDS             <1..216
                     /locus_tag="ACHA1B_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HFM8703648.1"
                     /translation="YEFVGMSVRKNGRLVIKYAKDNHAKRFMREENRKIDQKEFRQQY
                     EEEKEKTFKAIRWDWERQREIYMSKLW"
     gene            233..385
                     /locus_tag="ACHA1B_002985"
     CDS             233..385
                     /locus_tag="ACHA1B_002985"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703649.1"
                     /translation="MDVVKFLDDADIANDPNNPPQFTCEKCGKEMYPEYYRNALGIEF
                     KISDVQ"
BASE COUNT          164 a           56 c           95 g          105 t
ORIGIN      
        1 tatgaattcg ttgggatgag tgtgcgcaaa aatggacggt tagttattaa atatgcgaaa
       61 gataaccatg caaagcggtt tatgcgagag gagaatcgaa aaattgacca aaaagaattc
      121 aggcaacagt atgaagaaga aaaagaaaaa acttttaaag caattcgctg ggattgggaa
      181 cgccaacgtg aaatttatat gtctaagttg tggtgaaaaa gaatcaatcc caatggatgt
      241 agtaaaattt ttagatgatg cagatattgc aaatgatccg aacaatcctc cccaatttac
      301 ctgtgaaaaa tgtgggaagg agatgtatcc agaatattat agaaacgccc ttggaataga
      361 gtttaagatc agtgatgttc aataagaagg ttaatcatac aaaaagtcca ccggagaatt
//
LOCUS       DAYYEF010000199          400 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000199 DAYYEF010000000
VERSION     DAYYEF010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.214"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>400
                     /locus_tag="ACHA1B_002986"
     CDS             <1..>400
                     /locus_tag="ACHA1B_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM8703650.1"
                     /translation="AIVTDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVK
                     KAFSRIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTY
                     KSLKVEFVYQYTFETLQQLDLELFDYVNWWN"
BASE COUNT          129 a           63 c           79 g          129 t
ORIGIN      
        1 gcgatcgtaa cagacttgac ttatgtacga gtcgggaaaa aatggaatta tgtctgtttc
       61 attttggatc tgttcaatcg agaaattctc ggctattctt gtggagaaca taaagatgcc
      121 gttctagtaa aaaaagcatt tagccgtatc aaacaacctc tgacagaggt tgagattttt
      181 catactgatc gtggaaaaga gtttgataac caagctattg atgaattatt aacaactttt
      241 gacatcaatc gatcattgag tcataaaggc tgtccttttg ataatgccgt agctgaatca
      301 acttataagt cgttgaaagt agaatttgtc tatcaataca catttgaaac cttacaacaa
      361 ttggatttgg agttatttga ctatgtcaat tggtggaacc
//
LOCUS       DAYYEF010000200          380 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000200 DAYYEF010000000
VERSION     DAYYEF010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.215"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            1..380
                     /locus_tag="ACHA1B_002987"
                     /pseudo
     CDS             1..380
                     /locus_tag="ACHA1B_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612146.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          160 a           65 c           73 g           82 t
ORIGIN      
        1 tggttcattc aaagaaaaag ataatcttac gcctgaacaa aaagaattgt tagaactacg
       61 taaaagaaac cagcaattag aaatggaaaa tgatatttta aagcaagcag cgctgatatt
      121 cggacgaaga gacaagtaat cgatgcgaat aagcatcttt accctatatc agcgatgtgc
      181 agaatattag gtctatcacg tcagtcctat tattatcaat caaaaccaaa gaaagacgaa
      241 tcagaacttg aagaagtagt cgctgaagaa tttatccgca gccgaaaggc ctacggctca
      301 agaaaaataa aaaaagcctt atcaaaacga ggcattcaga tcagccgacg aaaaattagt
      361 agaatcatga aaaatagagg
//
LOCUS       DAYYEF010000201          376 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000201 DAYYEF010000000
VERSION     DAYYEF010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.216"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            82..>376
                     /locus_tag="ACHA1B_002988"
     CDS             82..>376
                     /locus_tag="ACHA1B_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HFM8703651.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTH"
BASE COUNT          133 a           62 c           76 g          105 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccatt
//
LOCUS       DAYYEF010000202          375 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000202 DAYYEF010000000
VERSION     DAYYEF010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.217"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..132)
                     /locus_tag="ACHA1B_002989"
     CDS             complement(<1..132)
                     /locus_tag="ACHA1B_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFM8703652.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DAYYEF010000203          321 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000203 DAYYEF010000000
VERSION     DAYYEF010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.218"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(<1..>321)
                     /locus_tag="ACHA1B_002990"
     CDS             complement(<1..>321)
                     /locus_tag="ACHA1B_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HFM8703653.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSL"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DAYYEF010000204          320 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000204 DAYYEF010000000
VERSION     DAYYEF010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.denovo.219"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..>320
                     /locus_tag="ACHA1B_002991"
     CDS             <1..>320
                     /locus_tag="ACHA1B_002991"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8703654.1"
                     /translation="LKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEG
                     KKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIF
                     KTKF"
BASE COUNT          133 a           30 c           56 g          101 t
ORIGIN      
        1 ttttgaaaaa agaaagaaat gctaatgcag ttattttaga ccctcataaa aataatccaa
       61 gagcaataag ggcataccaa aaatctggtt ttagaattat tgaagatttg ccagaacatg
      121 aattacacga gggcaaaaaa gaagattgtt atttaatgga atatagatat gatgataatg
      181 ccacaaatgt taaggcaatg aaatatttaa ttgagcatta ctttgataat ttcaaagtag
      241 atagtattga aataatcggt agtggttatg atagtgtggc atatttagtt aataatgaat
      301 acatttttaa aacaaaattt
//
LOCUS       DAYYEF010000205        28604 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.034, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000205 DAYYEF010000000
VERSION     DAYYEF010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28604
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.034"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(172..2310)
                     /locus_tag="ACHA1B_002992"
     CDS             complement(172..2310)
                     /locus_tag="ACHA1B_002992"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016757 - glycosyltransferase activity
                     [Evidence IEA];
                     GO_process: GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM8703655.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(2349..3935)
                     /locus_tag="ACHA1B_002993"
     CDS             complement(2349..3935)
                     /locus_tag="ACHA1B_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM8703656.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            complement(3925..5145)
                     /locus_tag="ACHA1B_002994"
     CDS             complement(3925..5145)
                     /locus_tag="ACHA1B_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA];
                     GO_function: GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8703657.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            complement(5157..5963)
                     /locus_tag="ACHA1B_002995"
     CDS             complement(5157..5963)
                     /locus_tag="ACHA1B_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA];
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HFM8703658.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            complement(6173..7453)
                     /locus_tag="ACHA1B_002996"
     CDS             complement(6173..7453)
                     /locus_tag="ACHA1B_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HFM8703659.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            complement(7497..9530)
                     /locus_tag="ACHA1B_002997"
     CDS             complement(7497..9530)
                     /locus_tag="ACHA1B_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703660.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            complement(9564..10415)
                     /gene="rfbD"
                     /locus_tag="ACHA1B_002998"
     CDS             complement(9564..10415)
                     /gene="rfbD"
                     /locus_tag="ACHA1B_002998"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA];
                     GO_process: GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HFM8703661.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            complement(10513..11541)
                     /gene="rfbB"
                     /locus_tag="ACHA1B_002999"
     CDS             complement(10513..11541)
                     /gene="rfbB"
                     /locus_tag="ACHA1B_002999"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA];
                     GO_process: GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HFM8703662.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            complement(11563..12135)
                     /gene="rfbC"
                     /locus_tag="ACHA1B_003000"
     CDS             complement(11563..12135)
                     /gene="rfbC"
                     /locus_tag="ACHA1B_003000"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HFM8703663.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            complement(12149..13015)
                     /gene="rfbA"
                     /locus_tag="ACHA1B_003001"
     CDS             complement(12149..13015)
                     /gene="rfbA"
                     /locus_tag="ACHA1B_003001"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA];
                     GO_process: GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA];
                     GO_process: GO:0045226 - extracellular polysaccharide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HFM8703664.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            complement(13115..13822)
                     /locus_tag="ACHA1B_003002"
     CDS             complement(13115..13822)
                     /locus_tag="ACHA1B_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HFM8703665.1"
                     /translation="MRSVCIATFNGGRYLREQLDSILSQLSAEDEVVISDDGSVDDTW
                     DILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWLETKVKKITD
                     YFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYIGAGMAFRSS
                     LKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIETHSKLRQKIS
                     WRVHLITALIKRKWFKR"
     gene            complement(13827..14654)
                     /locus_tag="ACHA1B_003003"
     CDS             complement(13827..14654)
                     /locus_tag="ACHA1B_003003"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFM8703666.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            complement(14654..15454)
                     /locus_tag="ACHA1B_003004"
     CDS             complement(14654..15454)
                     /locus_tag="ACHA1B_003004"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HFM8703667.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            complement(15447..16586)
                     /locus_tag="ACHA1B_003005"
     CDS             complement(15447..16586)
                     /locus_tag="ACHA1B_003005"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MraY family glycosyltransferase"
                     /protein_id="HFM8703668.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            complement(16791..17984)
                     /locus_tag="ACHA1B_003006"
     CDS             complement(16791..17984)
                     /locus_tag="ACHA1B_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA];
                     GO_process: GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HFM8703669.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(18063..18269)
                     /locus_tag="ACHA1B_003007"
     CDS             complement(18063..18269)
                     /locus_tag="ACHA1B_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HFM8703670.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            complement(18262..19404)
                     /locus_tag="ACHA1B_003008"
     CDS             complement(18262..19404)
                     /locus_tag="ACHA1B_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006270 - DNA replication initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HFM8703671.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            19916..20551
                     /locus_tag="ACHA1B_003009"
     CDS             19916..20551
                     /locus_tag="ACHA1B_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HFM8703672.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            20687..20779
                     /locus_tag="ACHA1B_003010"
                     /pseudo
     CDS             20687..20779
                     /locus_tag="ACHA1B_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323349.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            20893..21528
                     /locus_tag="ACHA1B_003011"
     CDS             20893..21528
                     /locus_tag="ACHA1B_003011"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8703673.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            21635..22873
                     /gene="mef(H)"
                     /locus_tag="ACHA1B_003012"
                     /gene_synonym="mefH"
     CDS             21635..22873
                     /gene="mef(H)"
                     /locus_tag="ACHA1B_003012"
                     /gene_synonym="mefH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_070509550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide efflux MFS transporter Mef(H)"
                     /protein_id="HFM8703674.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            23100..23519
                     /locus_tag="ACHA1B_003013"
     CDS             23100..23519
                     /locus_tag="ACHA1B_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016987 - sigma factor activity [Evidence
                     IEA];
                     GO_process: GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HFM8703675.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            23524..23763
                     /locus_tag="ACHA1B_003014"
     CDS             23524..23763
                     /locus_tag="ACHA1B_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703676.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(23988..24911)
                     /locus_tag="ACHA1B_003015"
     CDS             complement(23988..24911)
                     /locus_tag="ACHA1B_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HFM8703677.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(24943..25707)
                     /gene="map"
                     /locus_tag="ACHA1B_003016"
     CDS             complement(24943..25707)
                     /gene="map"
                     /locus_tag="ACHA1B_003016"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HFM8703678.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            25865..26305
                     /locus_tag="ACHA1B_003017"
     CDS             25865..26305
                     /locus_tag="ACHA1B_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HFM8703679.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            complement(26483..27052)
                     /locus_tag="ACHA1B_003018"
     CDS             complement(26483..27052)
                     /locus_tag="ACHA1B_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HFM8703680.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            27306..28538
                     /locus_tag="ACHA1B_003019"
     CDS             27306..28538
                     /locus_tag="ACHA1B_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HFM8703681.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
BASE COUNT         8687 a         5750 c         5008 g         9159 t
ORIGIN      
        1 aaatttgaaa agcaattttc gtgaatttct tcttatttct cggagttaaa cacttctgtc
       61 ccaacctcga cttatttttt tgagtcggca ccttctgcct ttttttgaca aaaaactata
      121 aaaagccgtt atgtgcgagc gaatcacaac ataacagctt tttattatag tttaatctgg
      181 tctcaacgaa aagtcgccga ttccttcttt tgttaaatta tcattgtaaa atggatcatg
      241 cgcaatatat gctggccatt tatcttgcat ttttttgatt tcaccagcaa aacgtctttg
      301 tttttctgga gtatcttcat aacctcttga tttagattcg aaatggtaca attctgcttg
      361 atgtgcatag acattgtaac gacccagttc ataaactttc aagcacaagt caacatcgtt
      421 gaatgctact tctaatgttt catcaaaccc gttaacagca ttgaagtcag ctgccttgac
      481 catcatacaa gctgcagtga ctgctaagta attgacgtca atgaccaatc ggccgaaata
      541 accacaatgt gttcgatcat agttattcaa tgcatgccct gcaacaccac cgattcctaa
      601 taatactcct gcatgctgcg ttgtatcatc tggataaaac agttttgctc ctacacagcc
      661 gattcgatca aactgtgcat aagaaaccat caccgtcatc caatctggct caatcacttc
      721 tgtatcgtta ttcaagaata aaaagtattt gccgtttgct ttttctgctg ctaaattgtt
      781 aattcgagaa taattgaatg gaatgtcaat caattctacg ataaagcggt ctttcagctg
      841 atgcttgtat tctgcaaata attcttgcat ttttggatct gtacttccgt tatccgcaat
      901 aatgatttca taatttgaat aagacgtttt ttcgatgatc gaatccacac aagtttttag
      961 atcttcatag ccattcttcg ttggaatgat cacactgacc aaatcctctt gcaagacgtc
     1021 ataagcaatc tcataaaatc cagaaattct gccaggacgt acgcttcctt tgatgtttct
     1081 tctagacagg gcatctgtca atgctttcac tccggaatca tagatataac ttttggcttc
     1141 gccattactt gcagttgatc ctgggatcgt ccgccaatga tacaagactc ggtcaatgtg
     1201 gtaaatatga tctgcaggga tttgttctgt cacacgaagg accaaatcat aatcttgaga
     1261 accttcatag cctttacgga aaccgccaag ttctttaaca atgcttgttc gatatacgcc
     1321 taagtgagag atataattat ttcccatcaa tgtatcaggc gaccagtctg ctttgaaatg
     1381 cggatcaaag cgattgccat ctgcatcgat tttatcttcg tcactgtaga tcacatccag
     1441 ttctggatgt acgtttagca cttttgccac ttcatataat gcaaatggcg gtaattcatc
     1501 atcattatct aagagtgcta taaattctcc ttctgctatt tccaatgcag aattagttgc
     1561 cagactgatg tgtccatttt cttttcggaa aacgactttg attctatcat cttttgcttg
     1621 ataggattcc agacactttc ggatagctgg atcagtagaa gcatcatcac tgatacatag
     1681 ttcccaatga tcatacgttt gatccagtac cgaatcaatg catttttcga gccatttgat
     1741 ttcaacgtta tagacaggca taagtatgga aatcaatgga cggtacgcaa atccttgtgc
     1801 ttctttcctt tgctctttca aatctggttt ctcatgacga ctgatccact ctgcatagtc
     1861 gatcgatcct ggcttcaatt ccaatttgac ccgacggatc gcttttttta cgccatgagt
     1921 ccttgcataa tttatccctt ttttcagtaa tctttttttt ctttcccatg aagattcaat
     1981 gccgtcatca taagggtatt taccgtttaa tttcacagct atgccatttt gatgtctcgc
     2041 tgtttggaag tctaagatgg cttttcctct cattttccct gataaacgta ccttaaaacc
     2101 gctttgggtc ttaacatcaa gattatataa atgattgata tccaatctta cgacatgtgt
     2161 tgcttcagca atcacatttt ctttttctac ctttatcgta gggatttctt tggtcacttc
     2221 atcaattgcc cagcccacaa taagcaaatc gccagtggcc cgttcacgag tgatttgatc
     2281 gataaatacg gcaatttctt ttttttgcac gattcgttta ctccttatct ttataagtta
     2341 atcattattt acatttcaat gatccatgat tggccatttt gagctactgc ttccactaag
     2401 aatgaacgtt cttgctcgca aaggattcgt aactcaaatc ccgcttctgt tccttttgcg
     2461 agctgttctg cttgattgac ttcttctcgt gaaacaggaa ttgcttcgaa aaatggcgat
     2521 tggtcagctg ataacttata ggacaagggc tggcgatccg aattagcgat tccccatccg
     2581 atgattttta atatttttgt ttctgcatcc cagattttct cgtcaataca tatagaaagt
     2641 tctttttctt ggattttttt cgaagtttct ttcttacgtc gtcctagtct atgttttatt
     2701 gtccattcat cactttccaa caatgtgcaa tagcgatttg tggttgtttt taacgtatgg
     2761 tctagtcttg tattttcctc aagaagatga tgattttctc tttctaattc gtcatttttc
     2821 tcagaaagct gctttgtgac ttcagccatg ggacgaatcg tttccaacaa ttctttcatt
     2881 gttggtgtca attccccgat aaagcgatag tgacaatgga tagtcacttc tttcccagaa
     2941 atatccgtta gaacgaactc tggtaattct ttcccatcaa acaaataaca atcatttact
     3001 gttttgacta cagcattcga atcgataaat gttagttttt ctccggcagc ttctgcgctg
     3061 aattcgataa agctaggttg ttgcgcgaag cgaaacacca ttctttctgt tgtttctgat
     3121 acggggaaac ttagtgtctc attttcccct gtgaaattat tgaatggtat ttgttggatt
     3181 gtttcatctt gtttcgtttg ctgggttact tctaacactt ttacataatt agaattttgt
     3241 ggctctgcaa tggaactttg tgctactgga tgtttcatca atgagaaaaa gtattggtag
     3301 acttcaccaa atggtcgcat tttgaaatca tagcgtacag cttccggcaa ttcttcataa
     3361 gttgatttta attctgtatc acctacagct aagtacaaat aatcttcaat attaatgaat
     3421 aatcccgctt tttcaaaaac tttttggaag ccatcatgag tataaaaaga attatgggtt
     3481 tcatctagga gaccataaga agcccacggc aattggttat tgaacaaatc gatcatgaca
     3541 gaattatgcg ccaagttagg gaatgtaatc aggatctctc cttcttcatt caaaaattct
     3601 ctgactttct tcaatgtttt tccaggatct accaaatgtt ctaaaacatc cgcaaacaag
     3661 acgtaatcaa atgtctgtcc agcataatag tttgcccact caaaactttc gatatcacca
     3721 taaaatccat cttgagcaaa ttcgctgaca aaatcgaaca attccttatc taactcaaca
     3781 atgctcactt cacattgttt tgctccgatt aaatgtttcg ttaatcggcc gtttccggga
     3841 ccaaactcta aaactttact tcctggtttg atctgtgcgg caatttttcc cacactgctt
     3901 tgttcatcta ggtccatttc aaaatcatat ttcattgcta tgagtccctt cttcccattt
     3961 atggtctaag accacgatgc cttctccgat ataagaaccg ctgacaaaca agttcatgta
     4021 ctttgtctta tataccaaag gaaccgttgc attttcttca aagaccgcaa cgtcaaaata
     4081 atattcacca gctaacaaac ctaacttttc atactccaga taaaagatat tctctccttt
     4141 tttccaagga atcttgatac catctagtag agtattaagt ccgcatacat aaaaattgtc
     4201 gactgttcgt agcgcaattc ctaaaaccgg atttttgatt gtatcatctt ttacttcata
     4261 agttacttta acgtatagtt tttctccttg ttccagcata tccaccggat ttttgtcttt
     4321 atccaacaat tccgctttcg tcacgtcgac gatatctgga gcggcgaacc gttctacttg
     4381 gtttttattc cgatccactg ttttaactga ttttttcttt aaaaagtttt cataattcgt
     4441 cgttacttcc atcgtatcgc catattcgac gacttctccg tttttcaacc aataggaacg
     4501 atcacaaaaa cgacgaatcg aactgatatc atgagaaacg aataaaatcg tctttcccga
     4561 gttcttgatt tctgtaaatt tttccataca ttttagttga aattcaagat cgcctactgc
     4621 caatgcttca tccacaatca aaatatcggg attcacattg attgctacag caaaagctag
     4681 acgaacgaac atcccgcttg aataagtttt tacaggttga taaatatggt ctccgatgtc
     4741 agcaaattca atgatatcat cgaccatttc atcgacttct tctcttgaaa atcctagaac
     4801 cattccattt aaatagatat tttcatagcc agaatactca ggattgaatc ctgatcctag
     4861 ttctagcaaa gctgagattt ttccttcgat ttccatcgtg ccggatgttg gtgtcagtac
     4921 tcccgtaatg attttcaaca ttgtagattt tcccgatccg ttttctccca cgaaaccgat
     4981 catctcacct ttttttattt ctacattcac gtttttcaac gcataaaata catcatgata
     5041 ggatttctta aaaggattga gggcttcacg aaatcgatcc gaaggttttg cgtacatatt
     5101 ataagatttt gtgatatctt ttagtctaat tgcatattct gtcatagcta ttctccttac
     5161 agcacatctg aaaaatgtgg tttcaatcta cggaacactg cagagccgat tacgaacatt
     5221 actaacgtga aaacccagaa atacaaagta tatgttccat gctcccagaa ccaagcttca
     5281 cttaaaaatg actcacgata accttgaaca acatagtaca gcggatttaa tttcaatatg
     5341 cttacaagac ctgaatcaaa ctgattaggg ctccataata tcggtaatgt ccacatgatc
     5401 aactgcagca cgatcgtaat taattgcatg atatcaggta aaaatggttg gatcgatgcc
     5461 gtcagccaag tcaatcctgt caagaaagca cacatgcaaa ataaataata aatcagctgt
     5521 aaagacattg ctgaaggata tataccattt ataagcgcga cagctatgcc aatcagaatg
     5581 aagaataagt gggtgtacag attggatagg attttcgtcg tgggcaagat acgaatattg
     5641 aatacgactt tctttactaa ataagtatat tcccgaaaaa caaccgtagt tgatgcaaat
     5701 gcatctgaga agaagaacca gggaatcatc ccggtaacta aatatacgat aaatgggtat
     5761 tttgcatcga tcatttgtgc tttcagtcca acaccaaata ccagccaata aatcaataca
     5821 gtaaatagcg gattgataaa cgcccataag attcctaaaa acgatcctgc atatcttgat
     5881 ttgaagtcat tgatcgaaaa ctgtagcaat aattttctgt tctgataaat gtccttcata
     5941 aataaataca aatctttaaa catttgtgtt cctccaagcg attttcagtg aattacagtc
     6001 aagtgccatt ttaccatatt tttggtaccg agctgcgttc ttatttcttt cttaattttc
     6061 tatgatacaa gattttctct aacgtttcta ttttacagaa gatgctagac aattgcaata
     6121 aaccaaaaaa ggctgcgacg gttgtcacag cctctctcgt attttgtgcc tatcaatgat
     6181 agcgttggat cctggaagaa tgagcgctat ctggttgttc ctcataagat gtatcatcat
     6241 aagtcatatc gtcatatgcc tcttccataa catagaattc ctccgcaact tctggttcat
     6301 catatcgatg aacggccata gccaacagga tataaataat cggaacccat gggtatgaag
     6361 tcaatgtatc ctccataaat gactgcatca tcaccgcaaa aaaggcccag ataaaagtca
     6421 tctgcccgtt ggataaatct gctttcaacg ttaagcgacc aataaaaagg ataagcagca
     6481 aagcagcaat cccaaatcct atcaatccat agatattcaa aatagaatta taactattgt
     6541 ggtttcctaa aaattggttt cctcgttgga agataaatgt tttcattcct agtaaaattt
     6601 gttcagattt ttctcctagc gtctgataga atttatgcca aatatcttct cgaccggtaa
     6661 acaaattgac tttttcagag acagccgcca gataagaaat cggcaaagct aaaagaatcg
     6721 taaccgtgta agcaataaat ggcgcacgaa tgacacgcat caacgattta ggtaaaagat
     6781 ccaatatcgc aaaaacaatc aacgcgacta atgcacctct agattggcag acccaaatcc
     6841 cgagaaaagc tgcaacaact gctactgcac cgatgattcg tacataccat cgttcaaaag
     6901 aactggcaaa tccactgatc aataaagcaa gagtcatcaa agaacttccg attatattcg
     6961 tattgatcca aatatcagaa agcgaattgc ctggagccca gatgctttgt ccttctggta
     7021 cttggatctc tgtaaataca cgatataacg tgattccgag gaagaccgaa aagacaatca
     7081 gataaatacc gcgatcccat tttgtccact cgatccattt aattactaaa caaaataaaa
     7141 taatcaaagg aaacagtaag tctccaaata aagactcatt tcttaattcc cgaaagtaag
     7201 aaaagaaaat gaaaagggca agcgcaacac ctagataaag aaaatcgacg ccttttgctt
     7261 tataaacatt taaaatgagc aaaatagcca cactaaaagc gataagtaat gaactattgt
     7321 tatatataaa caaagttgct ggaaaaccta accctgctgt ccaaacaaaa aagactagcg
     7381 tcagtaacaa aagcaagaaa ccgacactca ttttgttgac aaatttttgt acgattgctt
     7441 gaattatctc cactctcctt tctactaaca tttcaggatt attctcagct agcctattac
     7501 tgtacgacta gctgattttc ctgagtttgt gtttgtggta catctggata atccggatat
     7561 tctactttaa aaatcatata accgtcttta tccggtccat atagctgcgt gaactgcgct
     7621 tcatataatt ggttgtaatc agttaatggt cgtttactga tcacatagtc gatccctaat
     7681 ttttctgcgt cttcaaaatt caacgtgacc gaaaacatat ctggacgatc taaaatgaac
     7741 tttgtatctt ccttagcgat aaaagctctt gtatgagcat accgattata atacttctcg
     7801 tattcttctt tcggatcgat tttcttccat gcagctatat ctggataaaa gcgtactgta
     7861 ttgaaggatt tcactcccaa tgttggggtg aagttatata attcatcttc agacaaccaa
     7921 actttaccag gatcttgttg atcgattttt tggatttctt ttgccagtgt tttttcaaaa
     7981 atcgctcctg taccttctac gactggattg acgaaaaagc cagatacgat aactaaggcg
     8041 gcaaaagcga ggtaaaacaa gcgtctccag ccaaataatg caaaagctaa aatcactgtt
     8101 cccaacacag caactgcgat ggtttcaaaa tccgaaaaat aattatccat tttcgaatgc
     8161 gtaatcgcat agaaataaga ccatgcattt actgccaaca aaatgaattt ataccaaata
     8221 ggaataacat cttctctcca aatataagcg ataaaccaga tcgataataa acaagccgca
     8281 aaactaaaag taaggatggc tcttaatgga ggaacataag acagcagagt gatttctgct
     8341 agccattttg gcaacccaac ggtaatccaa aagatagaaa acagacaaaa aatcatcaaa
     8401 atacgtccca gtaacttttg ttcgctatct tttttgccaa ataacacaaa tggacttgct
     8461 aggaatacag ttggaaaaaa gtgatagaac agggccactt cagagttatt cgaatagttg
     8521 atatcttcaa aaggaatttt ccaatttgta aggaaagaaa aaaattcgcc aatcgtccac
     8581 tttcctccag tacttacccg ttttcctgga tataaggtat tcaaagaagc taacaatgcg
     8641 tcttttgacg ttagccagaa atgaaccatg actccgccaa taaataaaac tgcccctcca
     8701 atcaacacta catccaacag atcccatgaa actttcttgc tatagtaaat aagcaggcca
     8761 acaaaataaa aaatcagcaa gtacgccagc atcacttgat gggctgggta aatcactaaa
     8821 ataaacccaa taccgaaaat aaccaccaaa agcatcatca acgttcgtag ccatttttta
     8881 tcatgattgt agaaataatg ataaaaagca gtcatcagtc ccaaagtaaa gaaaatcaaa
     8941 tcgcccacat gttgcatgaa ccaccactgg actgctggag aaaatgtcag cgcaaatgca
     9001 ccgattagcg atagagcttt ttttctcttc gttaatatca tcagtacttc gaatccaagc
     9061 aagaccatga cgactaattt catcgcccaa taaaaggaaa gtcctcgatc tcttccgagg
     9121 aaaaagaatc cccagttgaa tggttttccg ataaccgtaa tatcctttac aggagaatta
     9181 tacgcaatga tcatgttttg tccgtttaat gaataatcct cgttcaccaa cggaaagtcc
     9241 tcttcagctt gtgagaggta aaaaggtgtc tgcaccagcc attcgtctga ccgcacttcc
     9301 cgattctgtc caaaaatcac atcagttttt ttcccatcgt ctctttgcga cacatattta
     9361 tcccaaacac caagtgaact tccgtttaaa ttaaaagtaa cgatgaccac gatgactaaa
     9421 acgccaataa gatagcggag ttttagaaac aggtcaagca ccaaattcga atctgcctgg
     9481 ttcgcttttg gcttttcttt tcgtcgtgca cttcttgttt gtttttccat atcatgctcc
     9541 aaattctatt tgataaaagg aaattactta ttcatttttt tggcagcttc cagcatttgc
     9601 gcaagtgctt cttgccaagt tggtatgaca aatcctaact cttctgtctt tttcaggctc
     9661 atgactgaat actgcggacg tgttgctttt tgcggaaatt cttctgacgt aacaggtgca
     9721 acttctacat ctgtatcttt caatatttct tttgcgaatt cataccaaga acagctattt
     9781 tcgttcgaca aatgataaat accaaatggt gctttttctt cgatgacata taccataaat
     9841 tctgccaaag tacgtgtcca agttggtcgc ccaaactggt catttactac agtcagtttg
     9901 tcgcgggttt ccgctaggcg ttgcatcgtg aagacgaaat tgtgtccata gatcccgaaa
     9961 acccaagaag ttcgtatgat ataatagtct tctaaaatct cttctactgc tttttcgcct
    10021 aataatttcg tacgaccata ttcatttagt ggattcgttt ggtcgtctac ttcgtattct
    10081 acatttttgt tttttccatc gaaaacatag tctgtactga tatagacgaa ttgagcattc
    10141 acagcttttg ctgcaagtgc tacatttctt gtaccatcaa cattgatctt ctcatctaat
    10201 tcttttgctt cttcttctgc tttatctact gctgtgtaag ctgcacaatg gaaaataaca
    10261 tcaggtttta attctgtgat gtaagccatt gttttctcgg catctgtgat atccaagtct
    10321 tttgcatctg ttgaaacata ttgcagattt ttttcatcta ataaatggcg caattctgta
    10381 cctagttgcc catttcctcc agttaataaa aacatatgat tatccgctcc ttgattttta
    10441 ttttaaaaaa gagacaggcg agcgcctgcc tcacatgtgt ttttccatta atacagtgac
    10501 attttctctg tattattgtc catttttggc atatgctgct tcaacggcct ctttttcttt
    10561 tttccaccag tcttcatgtt cttcgtacca tttgatcgtg tcagccaacc catcacggaa
    10621 gttcgtaaac tcaggcttcc atcctaactc ttcccgtaat tttgtcgaat cgattgcata
    10681 acgcaagtcg tgtcctgcac ggtcgtttac atggtcgtac gcatcttttg gttgacccat
    10741 catttctaag atcaattcca tcacggtctt attatcttct tcaccgtctg caccgatcag
    10801 ataggtttcg ccaattctgc ctttcgtcaa aatcagccac actgctgaag aatgatcatt
    10861 cgtatggatc cagtcacgaa cattctttcc ttcgccatat aattttggac gaataccgct
    10921 taagatattc gttacttggc gaggaataaa tttttcaata tgctgataag gaccatagtt
    10981 gtttgaacag tttgaaatgg ttgcacgtaa gccaaaagaa cgcacccatg cttttactaa
    11041 cagatctgaa ccagcttttg tagaagaata tggacttgaa ggattatatg gtgtttccgc
    11101 agtgaatttt tctccttcgc cttccccatg tcctggcagg tcttcacgta atggaagatc
    11161 gccgtaaacc tcgtcagtag atacgtgatg atagcgtaca tcatacttgc ggcaagcttc
    11221 taaaagtgta tacgtaccaa tgatattcgt ttgtacaaat gggaaaggat cttttaatga
    11281 attatcgtta tgggattctg ccgcgtaatg aacaactgcg tccgcttctt ttactagacg
    11341 gtccactaat tctgcatctg caacatctcc tacgaccaat tctacgcgat cgctaggaag
    11401 tccagccaag ttctctttgt ttcctgcata agtcagttta tccaaaacag tgacatgcac
    11461 ttctggatga ttgtttacca cgtaatgaac gaaattagag ccgatgaatc cggcacctcc
    11521 ggtaacaatg atgtttttca taagaaaatt tctccttaat tcttagattt ctccgtaaac
    11581 aaatggattt tctgcttcaa attcttttaa tgtcggatga cggtgatctt tttccgacat
    11641 aatcgctctt gatggatcaa ttggccaatc aatcgctaaa tctggatcat caaatgcgat
    11701 gcccccatct gcttctgcat tatagtaatt atcacactta taaaggaagt tcacatttgg
    11761 tgtcaaagta acgaatccat gggcatatcc tttaggtaca agcaactgtc gatgattatg
    11821 ttcagataag ataaatccgt cccattgacc ataagtcggg ctacctttgc ggatatccac
    11881 tactacatct aaaactgctc cagtgactac ccgaatcaat tttgtctgtg cagcttctcc
    11941 tttttggaaa tgaagccccc gaaggacacc agcttcagct gatagtgaat ggttgtcttg
    12001 aacaaagtca tatttcaatc catgttctgc aaattttgct tttgaataac tttctgtgaa
    12061 gaaaccgcga tgatcgccaa agacgtccat ttctacgatt ttgacatctg ttaattttgt
    12121 atctgttact ttcatctgta aggactcctt attcagcggc caaattcaat aaatattgac
    12181 cgtattgatt ttttttcaat ggctgtgcaa gggccagcaa ttgttcctta tcgatgtagc
    12241 ccatacggta agcaatttct tccaaacaag ccacttttaa gttctgacgt ttttcaattg
    12301 tttcgataaa ggtagatgct tcaagcaatg attcatgtgt tcctgtatca agccaagcaa
    12361 atccgcgtcc cataagttct acggatagtt ttcctttatc caaatatgct ttattgacat
    12421 ccgtaatctc tagttctcca cgttctgaag gtttgatacc tttagcgata gaaattacct
    12481 cattgtcata aaaataaagg ccagttacag cgtaatttga ttttggctga gcaggctttt
    12541 cttcaatcga caaagcttgc atattctcat caaattctac tacaccaaag cgttctggat
    12601 cattgacatg atagccaaat actgtcgcgc ctgtatcttt tgaagctgct cgttgcaaca
    12661 ttttagacag accgccacca tagtaaatat tgtcccctaa taccaagcag acactatcat
    12721 ctccaataaa ttcttctcca atgataaacg cttgtgccaa tccatctgga ctttcttgta
    12781 ctgcatattc gatctgcagt cctaaatcat ttccgtttcc aaataattcc ttgaaacgtg
    12841 gtgtatcttg tggcgttgaa ataatcagaa tttctttgat tcccgccaac atcagagtag
    12901 acattggata ataaatcatt ggtttgtcat aaatcggcat caattgtttc gatgttgcct
    12961 ttgttaaagg gtacagacgt gttccgctgc ccccagcaag aatgattccc ttcatggata
    13021 tctgctctcc tttttgattt caaatttcac tttgttatta tctcatcaat tgttatattt
    13081 gtcatggaaa tattaaggat ttaaacatct tttatcaacg tttaaaccat tttcgtttga
    13141 tcaacgccgt aatcagatga acacgccaag aaattttttg ccgtaattta gaatgtgttt
    13201 caatctcact cgcgtttaaa tcatgtcttc ggtacagagt taacggttct cttaggaacc
    13261 cagtcttctt tcctcccagc aaaccaatcc acatatcatg catcggcact tctgacggga
    13321 tcggcaaaat atcgggtttt aaagaagacc ggaaagccat accagcacca atatagtgac
    13381 ttcttatcac attattaagc catccttctt tggaatttcg aaacgaaaaa tacgaatcat
    13441 ggatctcttg cagctcgctg tccacaatga ttaaatcaga aactactact agctgatccg
    13501 gattctgctc aaaatagtca gtgatctttt tcacttttgt ctccaaccaa acatcatctt
    13561 ggtctgccaa aaagattaga tctcctttcg tctgctggat cgcataacca aaattagcga
    13621 tcaatccttg acgaggcccc gaaaaaagct ggattcgctt atctttttct gcgtattcag
    13681 ttaatatatc ccatgtatca tctactgacc catcatcaga aatgactact tcatcttctg
    13741 ctgaaagctg agataaaata ctatctaact gctctcttaa atatctgcct ccattaaagg
    13801 tagctataca aaccgaacgc acgaattcac accttccaat tcttaacata tgagcgcaaa
    13861 gtcatccgcc agatatgccg gtttttgacg gtcaagaact gtttagctgt tcttaacaat
    13921 aattgtcgtc ggtgactgga taaatgcctt tgatcatatt catgataaaa tcgattttct
    13981 gcttgtaaaa tagaacggta tcgattactt gaaacttttt catagtctaa aaccgaaaga
    14041 tcatgttcca ttcgtacagg aaggatctcc acagtttttt ccaactgatc cactttccaa
    14101 aacagccaat gatccaaaaa atctaaagaa aaagcaggat taaacccgcc aatctttttt
    14161 agaaatttga cagaccaggc aacacctgaa ttgattgcca tgattcgttc agctgttggg
    14221 ccttcaactt ctactgcttg agctgtacga ttgatataac gatctgaata taggggagaa
    14281 acttgtcggc tcccagaaaa aatcatcgga actgcagcaa cacattcatc tgtaaaggtt
    14341 actttacgca atagttcaaa ataatcgtcg actagcctcg tatcctgatc cagagtgacg
    14401 agacaacgtg ttccttcatc tgcttgagac aacgcaaaat tataagccac cgctaaacca
    14461 ggattttgcg gatcatgatg ataaacgata ttttcttttt caaacagctc attttgctgc
    14521 ctttgaggac tattatcgta aataataagc tgaatttgct tttcgctaag tgctttgctt
    14581 aatggtccat aagctggaga ttgactgaat agttgctgat aaagcacaac gactactaat
    14641 atttctggtt tcatcagaaa aaacgccacc cccacttatt gaaaaatttc atcatagaag
    14701 tcaaaaacac gcgaaacagt tttgcatttc gatgcgcacc cttcccgtaa aaatggataa
    14761 ctgcataaaa gggtgtgtac aataacttgt aacctgcttt ttcaaaactc aaacacaagt
    14821 cgttgtcttc aaagtacatg aagaaacgct catcaaaccc ctttatctct ttaaatttat
    14881 caatatcagc taccataaaa ctacctgaga tcatccgtac ataactatta gcatcagtag
    14941 gcaatcctcg gcattcaaac acagccagtc gtttgtcaaa cttttttttg acccatttga
    15001 aaggcacaaa gcgcaaaacg taatcaaaaa cagccagctg ctcacggatg aggtgctgag
    15061 ttgttccatc ttcattaaga atcttaggtg ctaacatcgc acattccgga tgttctttca
    15121 ataacaagac caatgctgta actgtctctt catccactaa aatatctggg ttacaaataa
    15181 tgccatagcg agaatcgcta gctatcagat tgtgattatg tccataacca aatccggaat
    15241 tttcatcatg aaaatagata tcgatgtagg gatatttcct atactctgtt agtctttttt
    15301 tgtactcggg aagtgaattg ttgtcaaaaa ttcggatttt tactgctgtt tcatctttta
    15361 cagttgaaat aaaattatct agtgtccgaa aaattttatc actgtttgcc gtcacaatac
    15421 taataaggat cggctggttt aatttgttat tcatctatat gacggttcca tttcttcaaa
    15481 tatttctgtt ttacttgcgt acggtactct ttattcccta aaaatcgcaa tgtttttaaa
    15541 ataaactgat gtttctcatt gatcagacca atcaattcaa ataataaaat tgcagcaaac
    15601 aacatggcaa taatcaatat gatcgttccg attcttccag tataattcat gaccatagct
    15661 gtgaaagaaa acatcaaagc catcgcataa atcgtcagga cagcaccttt atgagtaaag
    15721 cctaaactga ttagtcggtg atgaagatgt tttttatctg ctgtagaaaa agaaacacgg
    15781 tttgcttttc tcctaatgat agcaaaaaac gtgtctgtta ccggcactcc catgacgatc
    15841 agcaaagaaa tcgatgaaac aaaagtcacg ttcttcagcc cttgtagtga aaggacggcc
    15901 atcataaacc ctaggaatag agctcctgta tcgcctaaat aaatctttgc cggataaaaa
    15961 ttgtaaggaa aaaaaccgat aatacttgct acaagacaga aaataacaac tggaatatac
    16021 actgtagaag catggaggaa aaaatatcca atgattccta tcgtaattaa accgatcaat
    16081 gaaatccctg ccgccagccc atccaaaccg tcaatcagat tgaccgcatt cgtgataccg
    16141 aagatccaaa aaatcgttac gggaaaacta agccagccta gttggatata tccaataaaa
    16201 ggaagcgtga aggaatcaat acgtatatct gctacaaaat aaataataag agaagcaatc
    16261 aagatcccta tacttttttg tttaggtgtc agctcatatt tatcatcgag cactcctgtg
    16321 actatgatta ctaaagaagc aatcaagatc ggtacaatat acgattgagg gataatttta
    16381 cggaataaga ataaagtcga tataacaaat gaaataaaga taggcagtcc gcccgctgaa
    16441 ggcattggaa ctttatttat tcttctttca tttggtttgt cgaccatacc tgtttgtact
    16501 gaaatgattt tgaatacagg tgttaatatc agtgataata aaattgtcag aaaaaatctt
    16561 ataaccatac taaaagaaac aagcatatgg gcacctactt taattaagag tcataattat
    16621 tataaattat atatgtcttt ttgactatct ttttatatct tctcaaatgt ccgcaaagcc
    16681 ttattttatc ggctctacgg gcattttgct tttgtggtaa acctcgcata tctaggtcta
    16741 tcttcttata ttttccctgt caatcgtggt taaaatcgtg gtaaatactt ctatgcgatt
    16801 agacgctgaa cctctgattt tgcggtatct atggacgcat gagcgtacca gttcattgtg
    16861 atactgatgt ttgaatgccc catgatatac tgtaaatctt tcgggttcat gttcttgctt
    16921 gccagccttg tgcagaatgt atggcgtagc gtatgcggtg taatatgtgg caagggattg
    16981 tccttgtggt gcttgttgta tttctttacc atacggataa ataaggcgtt ataatcaatg
    17041 gcaacttttg gattaccttt cggattgata aacacaaaac cgctgtgtcc gtctacctct
    17101 atcgacttta tctttggtcg gctgttgata acccgttgaa atgcctgtat cgtttctttg
    17161 cttaatggca cttgccttat cccgcttttc gtcttaggcg tttcaatata atagccctgt
    17221 tccttactct ttagtaactg gtggtcgata atcacaactt cattcttgaa atcaatgtcg
    17281 gctactgtca gtccgcacag ttccgagata cgaagtcctg tctttaacag tatcagcaca
    17341 tcatcataat gcttgtgata cacgttgtcc gtcttaataa atgacaataa ggcttgctcc
    17401 tgttcctctg tcaatgcgac tttctctttg gtatcatttt ctatgacttc acttagcttg
    17461 aaatcaaaag ggtttttcct cacataatca tcttgtatgg ctatgtagaa tgacgctttt
    17521 aacgagcgtt tatggttgtt aatggtattg taggaaaagc ctttgtcttt catgcgtaac
    17581 gcccattctt tagcgtcaga gggttttatc gtatcaatgc tcctagcacc taacttgtcc
    17641 tcttttaata accgcatgag ttgttcccgt tgtttctgtg tgcttttctt cacatttgtc
    17701 ctctgtgcgt tctgtttggc atagagttgg caaagcgtca ttttcttgcc tgtgctgtcg
    17761 ataccgtcct caatatcccg tcttatctgc tgttccagtt ctcgaagtga gggtttttcc
    17821 cgttttccct ttggtgtcgg gtctgtgggt gtcaatctcc aagcatacac atattttgtg
    17881 tttcccaatg cgtctacata tttatataag tattttccgt ctgttcgttg gctctctcca
    17941 gtatgcagga tacgaccttt gttatcccgt cttttttctt tcatggtgtc tgctcctttc
    18001 cttgttggaa agagccttga tatgacttgt gttcatcata acacatacaa ggctcatttg
    18061 cattagattg cgtccaattt atcaataacc ttttcaaact gtcggcgttt aatctgtatg
    18121 cggttgccat tcataatgag ccagccagcg tccttgtttt cctctgccaa tcgtcttaac
    18181 ttgttttctc caatgcggaa atactttgac gcttcttcaa tggtaagggt gtatttttcc
    18241 catacgggaa tatcctgtgt attactcata aaacaccccc tcactttcga ttacgtctga
    18301 tatgtccgta cacatctgtt ccacaagcat ttcctgtttt tcagaaaggt gggtacattc
    18361 atcaatcatt ttcatgtagt ttgaacctgt cagcctgtcg atttcctcta tcatcacgat
    18421 tgacggcatg acctgtcttt ccagccattg cagagtgcgt tccatattga caggtacagg
    18481 gttcatttca aaaggtaaac tgtcatggga aatgaatatc tcccacaatg gatagtcagg
    18541 aaattccaca aaatcggtaa tgagataaaa caccagccca tgagggttat acgtcaataa
    18601 cagttcttca actgcctgta ccgccttttt gtcacgcaga cgaatttcaa aacggttgat
    18661 aatatcggta tgtttctttt tcgttgcctg ttccttttgt ttttcataca ggcagaaata
    18721 ttttgtgctt gcctttgagc cgatataaag ggtacttgct aaattacggt tttttccgct
    18781 taattttcca ccttgtacat tttcatagtt tttacagcga cattccgcac caccatttct
    18841 gtatttttca gatagcacag gaatatccag cagaccgcac atatcattga ttgccaagtc
    18901 aaaacgtcgg ataacaccgc cacagtcaag acagcggttt aagaatgaat accagtccct
    18961 gttctgtgcc tgtaagacat attccatgtt gcgtgagcct gcccctttta attctaaaaa
    19021 tacgcccatg tgttcatcat cagaagccat gaccttgatt tccccgtaag cataatgctc
    19081 cttatagcca taatacccat agtcataatg gataaaataa tctgctttca tgccaagcac
    19141 ctttcggata acttccaatg cgtcagtcgt tggaaaacgg acagacagat aatcaacgag
    19201 cagataaaaa ggcttatcgc agatatagta attcagacaa cgcaggataa tgttctgtgt
    19261 ttccttgctg gcgttagctt ttccgttctc aaagcggttg atactatatc ttgatacatg
    19321 ggtaagactt gcaagttctc cttgtgaaag accgctggca agacgtttgt tcttcatttc
    19381 aagtgcaaat tctaaattgt tcattgtatt cctccaatcc cacaatagcc ttgaaatacc
    19441 tgtaaaccac ctttcaaaaa gtgtgatatg tactatcttc ttaaaacctc tcattactac
    19501 tcacaggttt gggggtgtat ggtttttgac ttgtcttttg tgaaatagtg cccccctgtt
    19561 agataacggg ggcacagaca aggctcgcag gctcgccagc cgacaaagca tttcttcccc
    19621 ttgacacaag gtgtcatggc ggtaagcctg agaggcttcc gccaccgtgt cagaaatact
    19681 ttgtcagcaa gttctgtttt gccttttcta acaagttcca tttcaaccga tattcatatc
    19741 tacggattta atcagatagg tatttctttt tgaatgtttt tatatttcat tctattgtgc
    19801 ttattcgatt acaagaacat agtaattctt atatgcttat ttgtcaatat ctttttttgc
    19861 ctttacaaat catattaagc atgatagact tataatagcg aagatataac gagatatgga
    19921 gggttatgca atgaaaataa gccatttagg aaataatata cagaccataa gaaaatttag
    19981 gggaatgaaa caacaggaac ttgcggacaa aatcggtatc aatatgcaga gcctttccaa
    20041 gattgaaaga gggttgaact atcctgccta tgaaacgctg gaaaagataa tggaagtgct
    20101 ggacgttacg cccaatgaat tgttgtcggg agaatggaag tatgtcaatc aatctgaaaa
    20161 ggaagtctgt cagtttttaa gagccgaaga acgtctaaat gcagaactga aacatggaca
    20221 ctatgataac ttctttgaca gcgaggaaga atggctggaa tatgagttag aaaagttacg
    20281 ggaatatatt acagactata tcaacgggaa aagcattgaa gcgtccgacc tttacccaat
    20341 caaagaattt atccagcatt tgaagtttca aaaattatta gaccgctatg atgatttata
    20401 cagtatggat atgtttgggg aaagcataga gggacataag tataagacac cttatcaagt
    20461 cgtgaaaatg ataaacccga actcaaaaga agatatggaa ctgttacgag aagtattaag
    20521 gaataacaat tttgatgatg aggacgagta acttttttcc tcttgcgaga agatacagca
    20581 aacaaaaagc ccgatcaaga gtgcaaagca ccaccaatgg tggcaaagct cttgacaggg
    20641 ctttttcttt tctgttgtgg gcaatcaaga ggaagaaagg gataaaatct gatttgtggt
    20701 aaatcaggca aaggcaacgc aggtatcaca gtatgaattg acaccgcata aggaaagcaa
    20761 ctggaagatt gtagaataaa tgaaaaaggc ttgcattctg catttttata aaattgcaag
    20821 tctttatatt gacaagcata aaatactaag atatacttta atcagaccaa cggtttgtat
    20881 tggaggtaag ttatggcacg aaataaatat ccagaagaaa cagtaaaact cattttagat
    20941 gtttctacaa aaatgttttg tgaaaaagga tatgataaca catcattgca agatattatc
    21001 aatgaaacaa aactttctaa aggtgctatt tatcatcatt tcgattcaaa ggaagatatt
    21061 ttaaaagcaa tttttcaaag aattggaaat gaaaatgcag taatatttgc taaaattaga
    21121 gataacgata gtttaaacgg tttagaaaag ttaagagaaa tatttaagac agcggtattc
    21181 aattctaacc aaagcgtttt attgacagtt tctcctcaac tattaaacaa tcctcgtttt
    21241 cttgctatgc aaatagaaca aatgtatgaa attgtagtac ctgaatttgt tgaacccgtt
    21301 ttagaacaag gtatcaagga taagtctttg gagattgaaa attcacatga aattgcagaa
    21361 gttatcatgg tattaagtaa tgtatggctc aacccattag ttgaaatgac ggataaagag
    21421 ggtatggaaa aacgttgcaa tacattcaat gcccttttaa atggaatagg catagacaca
    21481 ttattagacg aagaaacaat ttctgcattt atacagtttt gtaaataact gtatttgtta
    21541 tccctatacg atagactgct ctataaaaga gcagtttatt taaaccatta tataaaccga
    21601 cggtctgttt gattaaataa aaaggagaga ttttatgcaa gcagaaaaaa aactttttaa
    21661 tcgtgatttt atacttgttg ttataggaca gataatttct ttatttggaa acgctatcct
    21721 acgatttgca ttaccgtact atttgttaaa agaaactggt tcatcagctt tgtttggtat
    21781 tgctacagcc tgctcttttt tacctatggt tattttgtcg ctggtaggtg gtattattgc
    21841 tgacaggaca aataaaagaa acattatggt catactagat tttgtaacag caatcataat
    21901 tttagtattt tatttgtcat tgggaaaaat tcctatcata cctttgttta ttgttgcttt
    21961 gatgttactt tatggtattt ctggtgcata tcaaccagcg gtacaagcaa gtattcctct
    22021 attggtatca tcagataaac ttaccgtcgg taatgctata ataaatcaag taaatacttt
    22081 agcaaacttt atcggaccag ctataagcgg agtagttttt caattttatg gtatcaatcc
    22141 cattttaatt gttagtatta tatgttttac tttttcagcc attatggaaa tttttatcca
    22201 tattccacac caaaaaagac ctcgtgaagt aggtgtaatt gcagttgcta aaaacgattt
    22261 aaaagatagt tatacctttt tgaaaaagga gaaacccatt tttatatccg taatcttttt
    22321 ggtttgcatt ttcaatttgg ttttaagtgc tgttttaatt gttggtctgc ctatcttaat
    22381 ttctgaagtt ttaaaaatgc cagatacact atatggtttt tcacaatcag cattatcatt
    22441 aggtggttta tgtggtggta ttttaacagc tcttgttgct tcaaagttaa aactaaaaaa
    22501 cctttatacc ttgttactta tttgttctgt ttctgtttta cttatgggaa tttcgctatt
    22561 tttagaattg cctgcaatag tttcctactg ggtagttaca gtgatgtgct ttgtggctat
    22621 gggtgtatct actatgtttg ttgttcaaat ttacactctt gttcagacac aaacaccacc
    22681 gcaattagta ggaaagataa tggctacgct ggtagcagtt gctatgtgcg gtcaacctat
    22741 tggacaaatg gtttacggta ttttattcga tgtatttata caagaaacat gggttgttat
    22801 gtttgtagct tctattgctt caatcatgat ttcaatatat tcaaaaagaa tttttcaaaa
    22861 gttagagata taatacaagg ggttaaatag tatgttaggc taaaaacaat atataaaaga
    22921 aaatttgaaa tctgctaaaa ggatagtgtt ataaaagaaa gagtaatatt gcagtattta
    22981 aggctcgcac aaatatatgt tttgtgtggg cttttttctt accatttttc tgtatttcta
    23041 aagggtataa acggtattcc gtttatatat ttcagcatta gcagaaaggg ggtgagatta
    23101 tgaggacatc ttctttcgag catatcgtca gattacagtt caattcttta atgctgattg
    23161 tcattaagaa caaagtgaaa agtcgaaaca gacagcttgc aagacattct aaacgtgaag
    23221 tattgttttg tgaaatagcc gaaacgaaac aagttgaacg tggaacgatt gatacctgtt
    23281 tttatgattg tgtatcattt aaagtcttgc actttacaat ttatgtatct gatgaaacac
    23341 ttggtacagt tttacataga ctgtcagaaa aacagcgtag tgcgatttta ttacgttatt
    23401 ttcaaggaat gaacgacaga gaaatttcag aactgtacca tgtatcacgt tctgctattt
    23461 gcagtagaag aactagagga ctaaggaagt taaaaatgct tttgagcgaa aggaagtaaa
    23521 gaaatgagta aagattatgg ctatccctct tttgaattga tttgcaaagc gtcaagcgga
    23581 gatgaaatgg cagttaaaga gattttgaag ttttatgacg gttatatttc taaattatgc
    23641 ttgcgtcctt tttaccactc tgaaagtggt aaaatcatta tgcaggttga tgaagaacta
    23701 aaaggagaaa ttcatacaga catgatgaaa gcaatattga aatttgaaat cggagtgaag
    23761 taatcaactg tataaaaaaa tcgggagata cacagtttcg tgctatctcc cttagtagtt
    23821 ttacggtcat atcaaggctc attcaatcgt ggtaaattcg tggtaagatg agtgtttttc
    23881 tatacttcaa aatgcttgaa tgtatagtgt ttatgcggat aattgaaaat tagatataaa
    23941 atttcaaata aattactgat ataaatttac aataagaact cttgtttcta ctttttttta
    24001 tgagaaaatt tagttttcaa tttattgaac cattttcggc ttggatctcg acgttttttg
    24061 atttgatgac ccgtcacgta ttcttgaaca actgcattga tgattccgcc caaaatgatg
    24121 atcgtagcag caaaattaag ccaaagcatg agtacaataa aacttcctat gatctgataa
    24181 ccgctgatcc tcgttgcaaa atacctagca tagatactaa acacttgtga taacagcatc
    24241 cagccgacag tagcgaagat cgtgcccgga atgatcgtct tcaacttcaa ctgagcatta
    24301 gggacaatta aataaatcaa gaacatgatg acaaataaag ctaccaatgt gattggccac
    24361 ttcaaagttt ggaactgatc gataaagttc acgggtattt gtacgattgg ctgaatagca
    24421 tccaaaatca gctgtcccaa cccaagaacg atagttaccc cactaatagc aatcatgaac
    24481 aagacaatga caattagtga gaagaaacgg acgatcaaaa aattttttct attttctacg
    24541 ccatacgctt tattcatcgc aatttgcaaa gcattgatac tttgacttgc agaccataaa
    24601 gccgctaatg cagaaacgga taacaagcct cctgaacttt gtgtcaaaag gtctttgatt
    24661 gcaggaccga taaactggta aacggtctca ggaatcactt ctcgtaaata ggtcagtaca
    24721 gtctcttgat cgatgtggag aaacggtaaa atattaccaa aagcaataat caatggaaat
    24781 aaagacaaga gtaaataata agcaacgacg acagaggtcg tactcatttc tgaatcagtg
    24841 atgcgctttt gagtcgtctc aataaagcgc atcagatttt cattttgttt tattttgttc
    24901 caaactttca tgtacctctc ccgtacctat tgactggata gatcaataag tgccttcttc
    24961 tccttgtgat gtcaaaattc ttggaccatc tttagtaata gccaatgtat gttcatattg
    25021 gcaagaaagt ccgccgtctc ttgtatacgc agtccagccg ttaggatcca ttttcatttt
    25081 ccaagttccg gtattaacca taggttcgat cgtgataacc atgccttctt tcaaccgcaa
    25141 cccttttcca gcttctccgt aatgaggaac tgctggttct tcatgaatcg taggaccaac
    25201 gccatgacca ataaaatcac gaacgatcgc tagattttcg ccttctacat aagtttggat
    25261 agcatgaccg atgtcaccaa tccgattccc tacttgtgct tgctcaatac cgatgtacaa
    25321 agctttcttc gttacttcca tcaatcggtc gatctcaggt gtagattctc caactacata
    25381 ggcccaacaa gaatcagaaa tgccgccttt caaatcgata cacatatcga cttttaccaa
    25441 atcaccgttt ttcaaaggct ttttacgagg gaatccatga caaatttcat catttatact
    25501 gatacaagtc gcatattcat acccttcaaa gccaatttgc gcagcaattc cgccatgact
    25561 ctcgatatag tttctgacaa atacctcaat atcccaactt gtgattcctg gttttataaa
    25621 atcacgcaga tttttatgta catctgctaa taaagctcca gattctgcca tcatttcaat
    25681 ttcacgtgct gattttaaag taatcatatt ttcgtctcct ttttacaaat ccctctcatt
    25741 ttaacatagc ggcatacatt tagccaaatg acattcccca ggtgtctcta ggttttattt
    25801 tcttttcaat gatgttttgg tataattcat aattgttaaa taattataaa cgaggaggca
    25861 catcatggct ttagcaaaaa tcgtatatgc tagcatgaca ggaaacactg aagaaatcgc
    25921 cgatattgtt gcagaagcat ttgaaaatct ggatatcgaa gtcgaaatca acgaatgtac
    25981 ccaagtagat gcagatgaat tcgaggaggc agatatttgc gtagtagcta cttatacata
    26041 cgatgatggc gatctgcctg atgagatcgt agacttttat gaagacttgc aagaattgga
    26101 tctattggga aaaatttacg gtgtctgcgg atctggtgat actttttacg atgaattctg
    26161 caaatcggtg gatgatttcg atgctgcttt tgcaaaaaca ggcgcatcaa aaggagccga
    26221 aaatgttaaa gtggatctga atgctgaaga agaagatatc gaaaatttag aagctttcgc
    26281 taaagaacta gtcgcaaaaa tttaatatac ttgcaataaa agagccatcc agatttattc
    26341 aatctgtatg gctcttttat tcattgcatt catggaagag ttcttcggga gttaaaaatg
    26401 catacgctgt aagaaaaacg aacttttcct tattttgaca catctcttgt tacctactga
    26461 tttgtggaac ttttgagtat attcaatcga tttcgattgg ttctttgaat ttcaagatag
    26521 catctatact gtcttggatc atcttttcaa tctgttcatc agttggatgg atgatgcttg
    26581 aagacatcaa agctgcgatc ccagtagcta tgatccatgt cccattatac aaagattcga
    26641 tctgctcttc tgaaagattc acataagctg gatcgcgttt cactgtattc acaaagtaag
    26701 tataagagaa attctgcatc tcttttcctc caccatattc ttctaagtac agtgaacgat
    26761 acaacttctt ctctcttctt gcaaaatgga tataattaaa agcaagatcg ataatcgtat
    26821 tccctgtatg ctcaacagtg aacacttcat attgtaaatg atcatagatc tgctcaaaaa
    26881 gagcttgtct caagtcatcc atatttttaa actcaagata aatcggttgc gtggaacaat
    26941 tcattttgtt cgcgatgttt ctcgcagtaa atcgtgtaaa tccatcggtg gcagctactt
    27001 cataagcagc tgccaaaatc tgttctctag taatcgtctt ttttcttgcc atatttttta
    27061 atctccttaa tttttttata acgcttccac cattgattaa tttcattgta acatgttttt
    27121 ttgatatgca aaattagttt ttgattttct tcacaagctg aaatagcaag tagtaacata
    27181 tatcatgaaa cttaacctta aaaaaataac ctcctttttt tatttaaagc ctcattgttt
    27241 gaatcataat taaatggtat catgctaata gttaccagaa aaaatggtga ggaggaattt
    27301 ttattatgtt atctgatttt aatgaacttc taaaaaaata tgcacgctta attgcagaaa
    27361 ctggcgtagc cacagaaaaa ggacacacag ttgttttaca gatcagcgtg gaacaggcac
    27421 cccttgctcg attgatcaca caagaagctt ataaactagg agccgctgag gttatcgttc
    27481 aatggactga cgaccagatc caaagagaat ttcttttaca tgctgcaacg gatcgtattg
    27541 agaatgtacc acaatctaaa atcgatcaag cggatgaatg gcttgaaaaa ggagcaagca
    27601 ggatcagcgt tgtttctgcc gatcccgatg catttgctgg tgtagatagc catcgagtag
    27661 cgtcttatca atcagcgaat ggcaaagcac taatgaattt acgcaaggca actcaagcaa
    27721 ataaagtcag ttggactgtc gtggctgcgg ctggtaaaca atgggcagca aaagtcttcc
    27781 cagaactgcc agaagaaaaa caagttgagg cattatggga tcagattttc aaaacgactc
    27841 gtgtctatga agaagaccct gtcttagcat ggaagaagca tgatgaaaaa ttagcaaaaa
    27901 aagcagaaga attgaatcga gaacaatttt ctgcccttca ctatactgct cccggtacag
    27961 atatcattat cggattgcct aaaaaccatc tttgggaagg cgctggaagc tataatgctc
    28021 gtggagaaaa attcatggca aatatgccga cggaagaagt gttcacagca cctgacagtc
    28081 atcgagtaga tggttacatt tcaagtacaa agccactgag ttatgctggc accatcatct
    28141 cgggtatgaa atttactttt aaagatggaa aagttgttga tttttctgcc gaacaaggag
    28201 aagatgtctt agcaaaactg cttgatacag atgaaggtgc gcgtcgttta ggagaagtcg
    28261 cacttgtacc tgacccttca cctatttctc aatctggcat catctttttc aatacattat
    28321 ttgatgaaaa cgcatcgaat cacttagcac taggttctgc ttatgccttc agtgtgaaag
    28381 gcggtacaga aatgtccgat gaagaattag cagaagctgg attgaataga agtcaaaccc
    28441 acgtagattt catggtagga tctgacaaga tggatatcga cggaatccgt gaagatggct
    28501 ctacagtacc gattttccga aatggcgatt gggcttgagt atactttcgc acacatgcaa
    28561 aaaataatgg ctctttgtca ataaggactg atgagttgtg caaa
//
LOCUS       DAYYEF010000206        22597 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.046, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000206 DAYYEF010000000
VERSION     DAYYEF010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.046"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            complement(134..577)
                     /locus_tag="ACHA1B_003020"
     CDS             complement(134..577)
                     /locus_tag="ACHA1B_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HFM8703682.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="ACHA1B_003021"
     CDS             complement(795..2135)
                     /locus_tag="ACHA1B_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0015171 - amino acid transmembrane
                     transporter activity [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HFM8703683.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="ACHA1B_003022"
     CDS             2404..3300
                     /locus_tag="ACHA1B_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HFM8703684.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="ACHA1B_003023"
     CDS             complement(3450..4391)
                     /locus_tag="ACHA1B_003023"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008677 - 2-dehydropantoate 2-reductase
                     activity [Evidence IEA];
                     GO_function: GO:0050661 - NADP binding [Evidence IEA];
                     GO_process: GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HFM8703685.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="ACHA1B_003024"
     CDS             4517..5638
                     /locus_tag="ACHA1B_003024"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HFM8703686.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="ACHA1B_003025"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="ACHA1B_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection-like protein
                     Eat(A)"
                     /protein_id="HFM8703687.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7465..7992
                     /locus_tag="ACHA1B_003026"
     CDS             7465..7992
                     /locus_tag="ACHA1B_003026"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HFM8703688.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="ACHA1B_003027"
     CDS             8203..9264
                     /locus_tag="ACHA1B_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MupG family TIM beta-alpha barrel fold protein"
                     /protein_id="HFM8703689.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="ACHA1B_003028"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="ACHA1B_003028"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016835 - carbon-oxygen lyase activity
                     [Evidence IEA];
                     GO_process: GO:0009254 - peptidoglycan turnover [Evidence
                     IEA];
                     GO_process: GO:0046348 - amino sugar catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HFM8703690.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="ACHA1B_003029"
     CDS             10177..12159
                     /locus_tag="ACHA1B_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose PTS transporter subunit IIA"
                     /protein_id="HFM8703691.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="ACHA1B_003030"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="ACHA1B_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HFM8703692.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="ACHA1B_003031"
     CDS             12881..14305
                     /locus_tag="ACHA1B_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005886 - plasma membrane [Evidence IEA];
                     GO_process: GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="basic amino acid/polyamine antiporter"
                     /protein_id="HFM8703693.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="ACHA1B_003032"
     CDS             complement(14486..15259)
                     /locus_tag="ACHA1B_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0140359 - ABC-type transporter activity
                     [Evidence IEA];
                     GO_process: GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HFM8703694.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="ACHA1B_003033"
     CDS             complement(15256..16161)
                     /locus_tag="ACHA1B_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HFM8703695.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="ACHA1B_003034"
     CDS             complement(16315..16635)
                     /locus_tag="ACHA1B_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HFM8703696.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17109..17795
                     /locus_tag="ACHA1B_003035"
     CDS             17109..17795
                     /locus_tag="ACHA1B_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HFM8703697.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17797..18741
                     /locus_tag="ACHA1B_003036"
     CDS             17797..18741
                     /locus_tag="ACHA1B_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HFM8703698.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18940..19584
                     /gene="pcp"
                     /locus_tag="ACHA1B_003037"
     CDS             18940..19584
                     /gene="pcp"
                     /locus_tag="ACHA1B_003037"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005829 - cytosol [Evidence IEA];
                     GO_function: GO:0008234 - cysteine-type peptidase activity
                     [Evidence IEA];
                     GO_function: GO:0016920 - pyroglutamyl-peptidase activity
                     [Evidence IEA];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HFM8703699.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19663..20940
                     /locus_tag="ACHA1B_003038"
     CDS             19663..20940
                     /locus_tag="ACHA1B_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703700.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            21198..22415
                     /locus_tag="ACHA1B_003039"
     CDS             21198..22415
                     /locus_tag="ACHA1B_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HFM8703701.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
BASE COUNT         7297 a         4131 c         4666 g         6503 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcgccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt
    16801 agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaagat gaatgctttg
    16861 caatttcata gaaagaagtt gttatttatt aatcatttaa aaaaaacagt aactagacct
    16921 tatttctata tattatcggg caataaatta aaaaaagctt taccttacaa taagtaagat
    16981 aatttttgtg ataaaaaaat aacgaaaaat atttaaaaat agtgtctatt tcgtgagaaa
    17041 acaactatat tttttatgtg ttttgcttta taattaaaaa aatattgtca ttttatggag
    17101 gaaaatatat ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg
    17161 catttaaatt agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg
    17221 gcggtcttgg cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg
    17281 ggatggcgat ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga
    17341 aagaatcagc ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag
    17401 atatttatgg gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg
    17461 ctggatttgt tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt
    17521 tagaagtcca tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg
    17581 tctgctggtt ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat
    17641 caacactgaa agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc
    17701 cagtggctat cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat
    17761 tagcgaagaa atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat
    17821 attttattag gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt
    17881 tacactggag taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt
    17941 ttctggacgg tcttaggggt agttattgca ggaggaagat ggcttccggc aatcgtgaac
    18001 ggtggcttga tctttgcgat gaccatacca gcaattgcta agaaagtcag caaaggagaa
    18061 agccggcttc catcaaaaga atatatggaa aaaatgtcag acaaactagg aatgaaaatt
    18121 tttattccag ctttgagtat cggtgtcttt gcgatcttgt ttgctctatt taccaattta
    18181 ggtgctttag tcggcgtggg cgtcggtgtt tttgcagcca tgctaatctt gatgttcttt
    18241 tctcgagata atcgaccaag tacattttta gatgatgcag cagatatgct gggcacagta
    18301 gggccgttaa gcatgttgcc aatgctttta gcttctctag gtgcggtatt tacaagcgct
    18361 ggagttggga cagtgatttc caatgcagta ggtacgatcg ttccagaagg aaatgtgaac
    18421 atcggcatca tcatttacgc tcttggcatg gtgatattta cggtaatcat ggggaatgca
    18481 tttgcggcca tcaccgtgat gacggttggg atcggtgcac cattcgtatt tagtcatgga
    18541 gcgaatccag cgttaatagg aatggttgca ttgacttgcg gtttttgtgg gaccctgctg
    18601 acaccgatgg ctgctaactt caatatcgtg cctgtagcga tgctggagat gaaagacaaa
    18661 tacggagtga tcaaaaacca gttgtttatt gcgttattta tgctagtttt ccaaattgct
    18721 tatatgattc tatttaaata atagaagaga ggggttgtga cagaataatt gtcgcaacct
    18781 cttctaacat tgtagtggaa cactattttt ttataagaat atattaagtt tgatctgtta
    18841 tgttatttaa actattgttt cctttattta cgctgttcaa ggaaaatggt atgataaaag
    18901 ataaccatat gttaaatcaa tcggacggag gaacaacaga tgaaagtact agtaacaggt
    18961 tttgatccat ttggtgggga caaagtgaat ccagcctatg aagcagtaaa aaaaatgcca
    19021 gatgaaatca gcggtgctga aatcatcaaa gtggaagtac cgaccgtatt cgaaaaaagc
    19081 agtcaagtag tcaaagaagc catccaacag caccaaccag atgtcgtgat ctgtgtcgga
    19141 caagcaggtg ggcggtcagc agtctcgttc gaacgtgtcg caatcaatct agcagaagca
    19201 agaatccctg ataatgaagg aaatcagcca ttcgatacgg ctttagaaga aaacggtcca
    19261 gccgcttact ttacctcatt gccaatcaaa gcaatgacaa aaaatgtaca agatcatggt
    19321 ctaccagcgt acatctctta tacagcagga acatttgtct gcaatgatat catgtatcgt
    19381 ttgcttcatt tgatcgaaac acaattcccg gcaattcgag gtgggttcat ccacgtgcca
    19441 ttctcacccg atcaagtgat cgatcgtcca gtgggtacgc cttctatgtc tttagaagac
    19501 attgcttctt ctttgactta tgcagttgaa gcagcagtag aaaataaaga agatatttcc
    19561 ggaaatgccg gaacaactca ctaatttagc aagaaacact ggctggttgc taacgttatg
    19621 ttagtagcca gctttttgta attagaaagg aaagaaacag ccgtggaaga atggcaatcc
    19681 gtctttgaag aatggtttcc aaaagaaatc agcaaaagct atcccatcaa aatttctaaa
    19741 caatacacaa gcagtcaacg ttgggagatc tatgcaaaat taacgaaaaa acagcgggaa
    19801 ctagtcgata agcaccgccg atatctaatc agctctcgtt ttatggaaga acattattta
    19861 gctgcaacag attgggtgtt ttctgacttc aagatcaatc cgttttttcg aacaaaacga
    19921 agccagcaaa aattgtattg tgagtgtggt agagaattaa aagtgcaata catcgttaaa
    19981 tcgccaaaaa ccggaaagat cctaaaacta ggcatcaacc actttgccga tcacctgcat
    20041 gtctctccga cagtggcagc ttcgatccat cagggaatga caaaagttga tctggcctta
    20101 gacgaattat tatggcttaa gcagaagaat atcgattttc ctgaaggact atggcaaaaa
    20161 tactgttttg tcttgtacca aaatcgtcgg atgaaacagc catatttacc ggatataaaa
    20221 ttagctcagc ggctcgcaga atttcgccaa gtagaaatgc cgatttacat agcggattat
    20281 caagcattgg aaaatgaaat caagaaaata agtgaacaca tcaatgggca gtcaaaaaag
    20341 cgacagataa aaaaagaact atttgacgac tttgcagaag aattagtaaa ggatgtagaa
    20401 gaattcttga tcaactatcg cgcattttta cgtaaagatt ggcaatccat cgtatatgaa
    20461 gaagtgccag tacatcctaa tgcttatttt gaaacattta tttccgtgtt gagaaagaca
    20521 aaacgtcaac gaacaccaga agtcactgct cagatggaat attttgcgaa aaaccaacga
    20581 ttcatccaac caaaaatcta tctatttatt tggaagcaat attgtcgcta tggttttaca
    20641 gaagggttct tcgacagcat tcctcggata gtcagaaatg gttttttaaa agtattgcgt
    20701 aaagaacgag aagctataca atctgctgat aagaaagacc gtacagtctc aaaagaaaaa
    20761 tggcaactag tagtgaaaga tatccaatct ggaaatgtgc aagagacaat cgacaaatgg
    20821 aaaggaaaac attatcgttt tactgaagct cagaaacaag cgttggaata ttatcagaag
    20881 ttagaagaat cactgcgttt caatgatgag gcaagaaagt atctgaagga attactataa
    20941 aaaacatact aagattagag gggaacatca ttgacgaatg atgttctcct ctattttcta
    21001 tttttagatt atagtgaaga gtgaaagaaa gttcgaacaa agccttgagg actacgagtc
    21061 cctatcaaaa accgaacttc tttactgtca ttttagaatc aggtttacgt atgttggggc
    21121 catgagcccg tgtataggaa attggaatcg aaatgaagca gtaaagttct ttcaaaactt
    21181 aaaaaggagg aaaacaaatg ccttacattc ttgcattaga tgtttcaatg ggacacagct
    21241 acagtgtcct atacaaagac gacacctgct tatttgaaga cgagattgaa cacactcaaa
    21301 gaggatttca tgcattactc gaagagatcc agcacttgcc tgagcgtcca ttgattgttt
    21361 ttgaagcaac ggggatttat tccagaccag tcgaaaagtt ctttcaagat catcactttt
    21421 cttactgttt gttaaacccg ttagaggcga aaaaacagat ggaagaaagc accttacgca
    21481 gttggaaaac agataaatcg gatgcccacc ggctcgcaca gactcatctt aaaaatcaac
    21541 gtcagccaaa agaagtacaa agcaattttt acttagagat gcgcgattta gcccgttttt
    21601 atcaagaaat tgagaagaaa atcactcgtc tgcgcatgga tttacacaac tgccttcaat
    21661 tgacttttcc agagcttgaa cagttctttt caaacaggct gaccccttac gcattgacat
    21721 tgatccgtct ttttccccat ccagattttg tattggcatc tactcggaca aaaataaaaa
    21781 ataaactgat caacgaaaca cggaaaaaaa tctccgcgaa tcgtgccgag caaaaggcag
    21841 atcaaatcat ccactatgca cagtgtgcct atccagctgt tgaaaaagac agtatccact
    21901 gtcaaaaaac gatctattac gccgaacttc tccaagattt actcgaacaa aaaaaagcac
    21961 tggcgacaca aatgatcaaa aaagccgaag gctctccttg ctttttgttg taccaaacgt
    22021 tccctgggat tggcgcactc acagccgctt tattgctcgg tgaattagga gatatcacac
    22081 gatttaaaac ccataaacaa ttgaatgcct ttgtcggaat cgacatccga cggtatcatt
    22141 caggtaagta tactggccaa gaccgcatca ataagcgtgg taatcccaaa gcacggaaaa
    22201 ttattttctt caccattcga aatatgattc gccagcaacg cgcagctcct aatcatattg
    22261 tcgattatta ctacaaatta aaaaagcaac ctatccctaa gaaagataag gttgccacag
    22321 ttgcttgtat gaacaagctt ctgaaatgta tgcacgctat ggttagggca catacagagt
    22381 acgactatgc gtacgcggtc tcagtggacc attaactaaa ccacttacag tataccactt
    22441 ctttgcccag atcgaaaatt ttttacgaac ggggctttat ttggtgtgct ttgattttgt
    22501 cgctttcgtt tacgagctat ttttcttgca ccttttactt gactaatcgt aggaaataga
    22561 ggctgggaca gaagcgttta actccaagaa ataagaa
//
LOCUS       DAYYEF010000207        16770 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.058, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000207 DAYYEF010000000
VERSION     DAYYEF010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.058"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            361..1224
                     /locus_tag="ACHA1B_003040"
     CDS             361..1224
                     /locus_tag="ACHA1B_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFM8703702.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            1324..1806
                     /locus_tag="ACHA1B_003041"
     CDS             1324..1806
                     /locus_tag="ACHA1B_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HFM8703703.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(2069..2536)
                     /locus_tag="ACHA1B_003042"
     CDS             complement(2069..2536)
                     /locus_tag="ACHA1B_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HFM8703704.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            2659..3510
                     /locus_tag="ACHA1B_003043"
     CDS             2659..3510
                     /locus_tag="ACHA1B_003043"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFM8703705.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(3761..5719)
                     /gene="nagE"
                     /locus_tag="ACHA1B_003044"
     CDS             complement(3761..5719)
                     /gene="nagE"
                     /locus_tag="ACHA1B_003044"
                     /EC_number="2.7.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0016020 - membrane [Evidence IEA];
                     GO_function: GO:0008982 -
                     protein-N(PI)-phosphohistidine-sugar phosphotransferase
                     activity [Evidence IEA];
                     GO_function: GO:0015572 - N-acetylglucosamine
                     transmembrane transporter activity [Evidence IEA];
                     GO_process: GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-specific PTS transporter
                     subunit IIBC"
                     /protein_id="HFM8703706.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(5716..6588)
                     /locus_tag="ACHA1B_003045"
     CDS             complement(5716..6588)
                     /locus_tag="ACHA1B_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HFM8703707.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(6930..7802)
                     /locus_tag="ACHA1B_003046"
     CDS             complement(6930..7802)
                     /locus_tag="ACHA1B_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HFM8703708.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            7930..8499
                     /locus_tag="ACHA1B_003047"
     CDS             7930..8499
                     /locus_tag="ACHA1B_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="HFM8703709.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            8566..9303
                     /locus_tag="ACHA1B_003048"
     CDS             8566..9303
                     /locus_tag="ACHA1B_003048"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HFM8703710.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            9534..10802
                     /locus_tag="ACHA1B_003049"
     CDS             9534..10802
                     /locus_tag="ACHA1B_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HFM8703711.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            11289..11753
                     /locus_tag="ACHA1B_003050"
     CDS             11289..11753
                     /locus_tag="ACHA1B_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="HFM8703712.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            11737..12366
                     /locus_tag="ACHA1B_003051"
     CDS             11737..12366
                     /locus_tag="ACHA1B_003051"
                     /EC_number="1.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016491 - oxidoreductase activity
                     [Evidence IEA];
                     GO_function: GO:0016657 - obsolete oxidoreductase
                     activity, acting on NAD(P)H, nitrogenous group as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HFM8703713.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            12720..14198
                     /gene="msr(C)"
                     /locus_tag="ACHA1B_003052"
     CDS             12720..14198
                     /gene="msr(C)"
                     /locus_tag="ACHA1B_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HFM8703714.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            14245..14691
                     /locus_tag="ACHA1B_003053"
     CDS             14245..14691
                     /locus_tag="ACHA1B_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HFM8703715.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(14890..15405)
                     /locus_tag="ACHA1B_003054"
     CDS             complement(14890..15405)
                     /locus_tag="ACHA1B_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HFM8703716.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            15522..16724
                     /locus_tag="ACHA1B_003055"
     CDS             15522..16724
                     /locus_tag="ACHA1B_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HFM8703717.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         5298 a         2988 c         3481 g         5003 t
ORIGIN      
        1 ggttgaactt ttacacaaga ttgtggactt gactgcaaag aaaaatccaa gcagcgttct
       61 gatcagcagt ttgaacaaca atttgctttg tacagtaggt agtaagcgga ttaactaagg
      121 gaataaaaga tatttttacc gctttgttta cttagaatct gtcttcccca aaatttattt
      181 ttctaaaggt aaaacataga taggcagata ataccaatta tccgttacga aacgctgctt
      241 gagaattttc tttagatcca tacaacattt tctacatctg actaaattgg ttcctgattc
      301 atcaagtaat tgactttctt tgataatatg ataaaaaggc aatcaaggag gaagataaat
      361 atgcttaaag atctgaacca attgatcgat tacatcgaag aacatttgac agaaggactt
      421 tcctataaaa taatagccga aaatacagga atctctgaat atcaattaaa acgcatcttt
      481 acgtttattg cagggatgtc gctaatggac tatatcaaaa accgtagatt ggctttggct
      541 aatcgcgatc ttctagatgg atcaagagtg acagaaacgg cgtttagata tggatatgaa
      601 acagtcgaag gtttttcaag agcttttcgt gattggtcag gatatctgcc ttcagaaatc
      661 agcagatacg gcatacaaaa atcttttcca cgcttgacat tttttattga tgtcagagga
      721 ggaaaatcga tggaatttcg tatcgaaaag aaagaacagt tttatgtggc aggtgtggcg
      781 aaaaaagttc ctgtcaaatt tgaaggagtc aatcaagaaa tacaaaagtt agcgcagacg
      841 atcacggaga ctcaaaggga agagatgcat aagttaggag atttatatcc aaatcaagta
      901 atcaacgttt cttatggatt tgatggagac cgcttggaag aaaagggcag tttgatgcac
      961 atgattggct ttgctacgac aaaagaaaat ccgtacgctg atttagaaat gcttgctata
     1021 gaagaacaca cttgggccat ttttcctaat aaagggccat ttccccaaac tttacaagat
     1081 acttggggga aaatctatgc agaatggctt ccttcttcag attatgggtt agtcgaagct
     1141 cccgagatct cttttacaaa atggggagag gatttcagta atgtttacag tgagatttgg
     1201 attgcagtga aagcaaaaaa atagttaaaa aataaaaata tccctagaaa aaagagcgta
     1261 atcgtgtcat ttccctttaa ttttatgtaa gatgaactta atataataga aagggtggga
     1321 gaaatggcaa agtataggat cgaagaaaaa ccagatttta cggtgacggg tattggtgtg
     1381 gaattgaaga gtagcaatac ggattttgtc ggtttggctg cagagaaaca agcatttgag
     1441 caaaaagtta tcggtaatgg aacaatagat gcattgaaac aagctgctga aaatcattat
     1501 ttctttacag tcaacgaacc ctataacggg aaaatgatgt actatgtcgg tgttcaaacg
     1561 agtcaggatg ttccaaacac tacgcgaatc atcccattcc caaaaggaac gtatcttgtt
     1621 gtaagcgctt tagcagaatc gcctgaagaa ttaagaaatg atttgacgaa tacggccttt
     1681 gggcatgttt taagagaagt agaagattac gcctatgttg ggggtccaaa tgctgtagtc
     1741 gaaatgggag ttaccaacgg gaaatatatg ggagaaatct ggataccggt agtcaataaa
     1801 ccatgataat atagaggtcg tgaaagtagc gctttgacct gagcattaga gaggaaaaat
     1861 gggaaatagc tttccatatt ttgcattttt cagaactaat gccgagggtc agctacttga
     1921 acaccgttta tcaagacgtc atgacttcag cgctttgacc tgagcattag agaggaaaaa
     1981 ggggcatgac aaggcttttg tcccccggag aataaaagaa tttatgtaga cgattccgat
     2041 cagaaaaatg caggcacagt agagagaatt ataaaaatct ctctacgagg cctgtgtttt
     2101 ctggtctttt ttctttttcc aaaacggcta ttttatgtat cagactatca agtgtgatct
     2161 tagccatttc ttcttctgcc tttttctgca gccgagcgta gctttcttct aaagcttctt
     2221 ggatattcgc accaacgacg caatttggat ttgtttttgg atcgacttgg ataagctgtg
     2281 tattaccttc gatgctgcga tagacatcta gtaaagaaat ctgatctgga cttttggcaa
     2341 gggaaggctg cggttttccg gtttttgtaa agatcaaacc ggattttttg agctgactca
     2401 tgattttacg tacatttgct gcatttgttt cgatactact ggcaatcatc tcactagaaa
     2461 gtgatcgggt atcttgaaac atttcaatat aggcaagtac atggattgca tcactaaatt
     2521 gcagagaata cttcatcagt tgtcatcctt tcattttttt tgcttgactt atcttaccac
     2581 actctttatg ataaaggtgt aatttataaa tgtacagctg taaatcttaa caaataaaaa
     2641 gaatagggag tggcaaatat gcattattta gtaacaggag caactggagg ttttggtggt
     2701 tatgcgctgg aattcttaaa aaagatggtt ccacaaaatg aaatctatgt actagtacgt
     2761 agtgaagaaa aaggagaagc actgaaagaa gctggattta atatacgtat tggtgattat
     2821 gatgatttag actcaatgaa agaagcgttg aaaggaatag atcgattgct ttttgtctct
     2881 ggcgttccag gaaatcgtca agccgaacat aagaatgtag tgaaggcagc acaagcagct
     2941 ggggtatctt atatcgctta tacaagtttt gcagatgccg atcactcgat cagtgtatta
     3001 gcgccagatc accaattcac tgaaaaaatg attaaggatt caggtatttc ccatacattt
     3061 ttacggaata attggtatgt agagaatgaa ttacctatca ttgggcaggc tttaaaaact
     3121 ggtcaattcg tttatgctgc aggaaatgga aaaacaggtt gggcattgaa acgtgaatat
     3181 gcagaagctg cagcaaaagt actagtagaa agtgactctc cagaaatctt agaattatcc
     3241 ggcaatctaa ctgactatga agaattagcc aaggcattag agcgtgcgac aggtaaagag
     3301 ttagaaatta ttgaagcaag tgatgcagcg tttgtcgaaa atctaaaaga agccggattc
     3361 cctcaagaag cagctgacat gtttttagcg atccaacatg atattaaaaa ggatcagtta
     3421 gctatttcct ctgatgattt agaaaaagta ttgggaaaac cattaacttc tcttgaagca
     3481 gcattaaaag aaatattgga tcaggaataa tgtataaaga ggttgtgaaa aagccgatta
     3541 gttttgagta tgaagaaaaa ttttgtgaaa aagctgttct gcatcaagta ataagaagag
     3601 tcaaataaaa aatagctctt catatgtttc gtttagctgg acttattacc gcggagttgg
     3661 caggagaacg ccgtttttat tcggaaaaag gagctgagac aagatttttg tctcagctcc
     3721 tgtttgttta tcgataaaaa agtctgggga agacgatggc tcaggctttg ttggaaacag
     3781 agccgatttt atcatttgct tttacatcac gtgcgggttc gatttctaag ctttggactt
     3841 tgtcgccatt tgtgaataca acgaccatat ccgtgttttt gcctgcagat tgaatagcgg
     3901 caagatcaac taaagcaatc aattgacctc ttgcgacttt ttgaccttct tctacatata
     3961 aagtgaatgg ttcgcctttt aagtcaacag tgttgatgcc catatgaagc aagacttcga
     4021 taccagcatc tgtttggatt ccgacagcat gtttcgttgg gaaaatgttt gtgatcgtac
     4081 cagcgattgg agagaagatt tctccatttt ctggtaatac agcatagccg tcacccatca
     4141 ttttttccgc gaatacatca tctgaaactt cagtgattgg aatcagtttc ccatttgcga
     4201 tagcgtaaat atcttgttcg atcgtttcac cggcaaatgt ttctgtttta accacggtgt
     4261 ttgtttgtgc aggtcgtgct gcagcaccac catgtagttt tgccatctca tctgcaacga
     4321 attgtacttc tgtacctacg atgacttgcg cattttttcc gtcgatgatc ttcataccag
     4381 gtacgccagt ggctttgatt ttattttgat cgatcaggcc tgtatctttg acttgcaaac
     4441 gaaggcgtgt agtacagtta tcgatcgaag ttacattgtc ggctccgcct aatgcagcgt
     4501 agattttgct tgcttgtgcc gcatatttat tgtctgaatt agtcgttgca gtatcgtcat
     4561 ctgaaagatc tgcttcctcg cggccaggag tcatcagatg gaattttttg atagcaaagt
     4621 taaagccaaa gtagtaaatc actgctgtta ctaatccttg gacgatcaac atcaatggct
     4681 gattcgcaat cggatttttc aaagatagga agtaatcgac aaatccggca ctaaaggcaa
     4741 atcctgctgt ccaatggaag aatgcactca ctgctaaaga aatcccagtg aaaattgcat
     4801 gcaagacata taatggccaa gcaacgaaca taaatgaaaa ttcaagtggt tctgtcacac
     4861 cagtaaagaa tgaagcaaaa gctgctgcta gcatcaagga agctgttttt gctttgtttt
     4921 ctggacgtgc atttctgtaa atagcatatg ctcctgctgg aagcccgaac atcatgattg
     4981 ggaaaaatcc agcttgatac attcctgtta cgccttttgt tccttcagaa gccaaaaatt
     5041 taccaatatc attgattcct gctacgtcaa accagaacac ggagttcatt gcttgatgca
     5101 atcctgtagg gatcagtaaa cggttgaaga agccataaag acctgcacca ccccagccta
     5161 aactcaaaat gaatttagca aaagaaacta aagcagagta aaccggaggc catacgagca
     5221 gtagcactgc actgatcagc aacatgacaa aggcagccaa gattggcact agacgcttgc
     5281 cgctaaagaa agataaagcc atcggtaatt ttgcttcgtg gaaacgatta taaagagctg
     5341 ccgcaatcaa tccggcaata ataccaataa atacgttact gatctgagca aaagatggat
     5401 caactgattc tggtttgata ttcaataaag tagctactga atcagttttt aaaacattta
     5461 ctggaacttc aaatgcgacc aaacctgcca aggcagcagc acctgatttg tccactgaca
     5521 tccctagtgc taacccaacg gcaaacagca aaggtaattg acctaaaact gcgttaccgc
     5581 cagcttgtaa aaaatgagcg acaatgtcgt tactataaga tgcccaccag tttccgatcc
     5641 ctactagtaa agcagcagca ggtaagaccg caactggaag ttgaagggaa cgtcccattc
     5701 gttgtagata tgctttcaat ttttttcctc ctcatgattg ttaacatttg tttgtacgat
     5761 tgcgcttctt aaacgctcga tatggatggc caagtaaccc agttcttctt tcgtgatcgc
     5821 gagctggtat tctttggtca gcaacacacg gattttttta gaaatcttat agctttctgg
     5881 gtattttcgt ttgaccattt ctacgatttc cgtgtctaaa acagcatatt gttgcgcatg
     5941 ggttcgttgt agaagcagtc gtaaatgatt caccagtctt gaataattca gtgaaaatgg
     6001 ttctgaatgg atatctgttt ccaattctga ttccactaaa tggatgatgt cagatacaat
     6061 cgtcacttca cggatactgc gatggttatt gttccgaccg cttcgtccgc tgtgaatatg
     6121 gattgcgata tatcctgctt cgtcataagt atatggaatc ccaagctctt ttgtcagata
     6181 ctctactgcc cattgagcaa tactgaattc atcactgtaa agcacttcga tttctcttaa
     6241 aagtttgttg cggatgacga taccgttatt aatgttctcc gcagaaaaag caatgtggtc
     6301 ggtcaaagcg atcaatacat gttcattcaa cttttccatc aaaacagttt ccgcatgatc
     6361 aatgatcgtt tctgctgcaa ataaaaagcg ttcatcaatc tgattaagta aattttgcaa
     6421 cttgatttga ccttctggtt ccatgacaaa tatccgttcg acatcacgat caaaaatcaa
     6481 atcatttctt tttctgtcaa atccaatccc ttttccaata gctacttttt cctgtccacc
     6541 gtcatctacc aatactgcat tttgattaaa gatctttttg attttcatgc gcgcaccctt
     6601 tttgaagatt tggttttcac gtttgctaga ccagttgatt gcggccaaac aaaaatagac
     6661 acgaaaaacc tcctagggaa accatgttcc tcagagattt ttcatgccta gtatgatcta
     6721 gtcacatgaa acgaattatt gttaacgtaa tcaattttat atagacagtt atgttttgtc
     6781 aattcttttt ttataattat agtaatttac tggaattatc agaaataaaa ggaagaaata
     6841 aattaagaaa cttatgttat ttaatcgttg gatcttttgc ttatcttatt cgttgttaaa
     6901 aagctgaaag cgaaggaaaa aaactctact taactgtatt tctccgttag gacatctaaa
     6961 aatttacgag cagcaggaga aagaggctgg tcttttttcc aaatgagatt cagtgaagct
     7021 tgtaatggcg gatcgagtgg gatgaatatt ttttccgtcc cataagtatt gatgatccca
     7081 tctagagcta atgcaccaaa agtcccgtta tcgaccatca aagaagcatt gtacaataag
     7141 ttatatgttc cgacgatcga taactgatct atgctgaaac ctagccattc agctagttga
     7201 ctgtccactg acgtttgccg ggaaatgatc aaaggaacag ttttcagttc ctgcggatgg
     7261 atgacggttt gctttgctaa aggatgattt cgatgtatca aaagtcccca acgatcttgg
     7321 gctggcagtc gaaatgactg gtatttttgt ttgtttgtcg gttcgattac gagtccaaaa
     7381 tcaagtaatc cgctatccag tttgtctatg atatcatctg cattcccgct atataaatga
     7441 aactggatat caggatgcgc cttgatcaac gaatgaaggc tatcagaaat gaaagagatt
     7501 gctttagttt cgcctccgcc aatgtagatt tctccagaga tgattgcgtc atttgttaaa
     7561 ttgttcgccg ttttttctac caacgacaag atttcttttc cttttgaata aagatatcga
     7621 ccagaatccg tcaactgtat ctctcgggag ccccgagtga aaagtgtcac accaagttct
     7681 tcttctaaat ctttcagttg ttttgagaga gtaggttgcg tgatatgcag agattttgct
     7741 gctcggctga tatttttttc tctagctact gctaaaaaat acgtcagtat acgaatatcc
     7801 attttttccc tcctgttttt aaaaaagcat accactaagt atagttaaaa ggaatagtta
     7861 agtatgtttt ataagtatta gacatgataa gccgtccgtt ataaagtaag gataaaagga
     7921 gggagcaaaa tgacaagcct catcgaaaaa caaatcgtca ataaagagat tcgagtaacg
     7981 gatccgctct ttgaagtgat ccatcagatc caagctgaaa acgaagagcc tttagcagcg
     8041 ctgaatactg ggtaccatga accagcagat atccgcaaac ggctagaaaa tatcattagt
     8101 gacaaagtag atgatacggt gactgttctg ctgccttttt atacagattt cggcaaacat
     8161 attagtatag ggaaaaatgt ctttatcaat cgtcaagtga tgttcgttga cttaggtggc
     8221 atctgtttag aagattcagt attgattggt cctcgtgtca acctcatcac ggtgaaccat
     8281 ctaaccgatc caaaagaacg aagaggcttg ttagtaaagc caatccacat caagaaaaat
     8341 gcttggatcg gagcaggagc aactattctg ccaggcgtaa cgattggcga gaatgccatt
     8401 gttgcagcga atgcaactgt tacgaaagat gtcccagaca ataccatcgt tgcaggaatc
     8461 cctgccaaaa tcgtcaaacc tgtcgaacgg attatttgaa cagtaagatg aaataagaga
     8521 tagtgagtat aagcaagaga tttttcaaaa caggaggaga atagaatgaa tgatttatca
     8581 gaaaaagtga ttgtcatcat gggcgcttca agcggaatcg gtgaagcaac aacgaagcta
     8641 ttagcagaaa aaggggctaa actagttata gctgcacgcc gagaagatcg cctaaaagca
     8701 ataaaagaat ctttaccaga agctgagcta tatattcaaa cagcagatgt aagagatttt
     8761 gcacaagtcc aagcagttat cgatttagcg atggaaaagt tcggtcgaat cgatgtattg
     8821 tacaataatg caggaatcat gccaaccgct ccattagttg aaggtcaccg tgatgaatgg
     8881 caaaatatgc ttgatatcaa catcatgggt gtgttaaatg gaatttccgc cgtacttcca
     8941 atcatggaaa aacaaaaatc tgggcatatc atttcaactg attctgtggc gggacatgtt
     9001 gtttatcctg attccgccgt ttattgcgga acaaaatttg ctgtccgtgc aatcatggaa
     9061 ggattacgtc aagagcaacg gcaaaataac atcaaatcta cgatcatctc tccaggagct
     9121 gttcaaactg aattatatca aaccatcagc gacaaaaagg ctgctcttga acttcatgaa
     9181 gcgcaaaaag aatggggatt gacctccgaa gatatagctt ctgctgtagc atttgcgata
     9241 gaaacgccag accggatgtc tgtcagtaac atgattatcc gtccgacgac acaggaagta
     9301 taatccataa cggataatat ccaaagagaa ttacttgtta aatagttatt caaacgacca
     9361 tcaatttaag gcgtgaatgg agaagaatat tcttcattta cgtcttttta tgtagaaaaa
     9421 gcaaatttat caaaaagaaa caaatgttat ttaaatatgg acattgactt gcttttactt
     9481 ttttagttac actgttattt aggaaaagtt tcataattca aaggagaaaa aagatgaaag
     9541 caaagaattt attatttagc gttattcttt taggaaatct agcagttgcc aacacaacag
     9601 tgctagctga agaatcgaca gaaactgtcg caactcagac atcgagttct tcagaaacag
     9661 gaattgaaaa cgatacagag agtactttgc agtcagctac tgtctcagaa aatacaattt
     9721 caaccgaaga accaacaact gaaacaacag aacaaacaca aaccgaagac agtacatcag
     9781 cagaagctca gaacaatcca gagaatgcag aagaaatcac gaaccaattg acagatgggc
     9841 aaacattgac acatacccat caagcagatt tgtctgaatt cgaaaactat actggctatg
     9901 ctttttatgc tcgctcatct gctaattctc aacaagcgtt cattgatagt attgcctcaa
     9961 ctgcacaaag tttggcaagt gccaatgact tatatgcatc agtcatgatt gctcaagcca
    10021 tcgttgaaag tggctggggg aacagtactt tggcttctgc ccctaattac aatctatttg
    10081 ggattaaagg aagctataat ggccaatctg ttacgatgcc tacttcggaa tatgtgaatg
    10141 ggcaatggat tacggtgaat gccgctttta gaaaatatcc ttcgtacaaa gaatcattgc
    10201 aagataacgt aacggtattg aagacgactt cttttcagcc aggcgtttac tactattccg
    10261 gtgcatggaa aagcaatacg aactcttaca aagatgctac ggcttggcta acaggtcgtt
    10321 atgccactgc gcctaattat ggttctacat tgaacaatgt aatcgaaacc tataatctga
    10381 cacagtatga tacagcacca acttcaactt ctccgatgta tcgtctgtat aaccgtcata
    10441 caggagaaca tttatataca ttgaatgccg gagaaaaaaa ttatctgcca actgtaggct
    10501 gggaatatga agggattgct tggcaagcac caaacagcgg acaacctgtc taccgtttat
    10561 acaatcctta cagtggagac catcattaca caatggcaca atctgagatc aactctttaa
    10621 caaaaatcgg ttggcgttat gaaggtctaa gtttttattc tggtggttcc aagccaattt
    10681 atcgactatt taatccaaat gaaaaaactg gtacccatca ctataccttg agtgctaagg
    10741 aaagagattg gctaacaccg atgggctgga gatatgaagg aataggattt tatggttatt
    10801 aaaaagaggt agtgaaaaag ctgccctgca tcaagtagta agaacagcca aacaaaaaca
    10861 gattttcatg ttttttgttt ggttgaactt attaccgcag atgcaagttt ttgaacaccg
    10921 tttactcaaa aaaggttgtg acaacatctt gtcataactt ttttattact gtttaagcat
    10981 actgatccaa tttctaatat tcgacgggat tcttgcaaaa ggcgatttcg gaaatttttg
    11041 gcggtgtaaa attttctact gcagaagagc tatcttctat agtttgataa gaatcaataa
    11101 tcttggtttt agcgttgtgc tttctttatc attttttccg ttcattctac aaaaaatttc
    11161 ttttctctat acttttctat tgagagcgtt ttttttatta cacagctgat tctttgactt
    11221 ttttcttttt ttattctatt attgacaagt caatcgttga cgagtcaatt attagaaagg
    11281 aggaaattat gtctttagaa gagattagtc accttttata tcaaatcaaa ttagccgatc
    11341 aaaaaatcgt ccagatcttt gaagaaaata tcggtataag tcttactaga tacgagatca
    11401 tgatgagact gaaagaagaa aatccattgc tacaaagcag tttgcaagaa aagttgcaga
    11461 ttgatcaagg agcagttact cgtcatctga aggtattgga agcaaatggc tatgtttcgc
    11521 gtcagagaaa tcctcagaac aaccgggaag tgtatgtagc gctaacagaa aaagcccaga
    11581 agaaaatcga gcattgtgaa atggaccata aagatacagg ttccgtgcta tccccggctt
    11641 tcagcgatgt agaaatgaaa caatttctaa cacttttaga taaattgaat acccaacttt
    11701 gcaatataac aacagaaacg aaagaggtta ataataatgg aacaaaaaaa tgatttttca
    11761 acaattatga ctggtagaag atccgttcgc gtatatgatg aaacatacaa aatcccacac
    11821 gaagaaatgc tggaaatgat caaagaagcg acgactgcac cttcttctgt caatatgcaa
    11881 ccatggcgct ttgtggtcgc tgaaagcgag gaagcaaaag aaatcttgcg tcctttgatc
    11941 cgtttcaata cgagacaaaa tgatacttct tctgcaatgg tcatgatttt tggcgatatg
    12001 caatgttacg aatatggcga agaaatctat aaccaagctt acgaatcagg gaagatgcca
    12061 aaagaagtca gagatcaaca attagctgcg atcattcctt attacaagag tttttcaaga
    12121 gaagaaatga acgatgtagt caaagtcgat tctagcttag cggctatgca attcatgtta
    12181 gttgcgcgtg atcatggcta tgaaacaaat ccaattggtg gagtcgaagc agatcagttg
    12241 gcagaggcat ttggtttgga taaagaccgt tatgttccag ttattatttt atcaatagga
    12301 aaagcggtag aagaaggtta cgagtctgtt cgtttagcac cagaaaagat cactacgttc
    12361 gaataaaagg ttttcagtta ctattcagta gctattgctt tttttgaatc gtgtgtggta
    12421 acctaataaa aaaggaggtc ggaaaaatga ctgcatcgat gaaattacgt ttcgaacttt
    12481 tgaataacaa ctaaataaat tcaaaagaca tgtataaaca acaatttcat ggatggagta
    12541 tgtccatttt ttcgaacgac agtagaatag gtgaaagcta tgacagattt ggtgatttag
    12601 tcatagttat ttcgttcaga gtaggaaaag atgtgatgca gtttttttgc aaacagattt
    12661 ttctgctctt ttttagtatc gataattgtt gttttacatg aaataggagt gtaaaacata
    12721 tggaaaattt agcagtaaat ataacaaatc tacaagtcag ctttggcaac cagctagaac
    12781 tatctattga ttctcttcgt gtctatcagc aagatcgtat agggatcata ggagaaaatg
    12841 gtgtcggtaa atcgactttg ctcaaactaa tagccggtga actttttccc gatcatggga
    12901 aaatccaaac agagatcacc ttcaactacc tgcctcaatt aacctatctc gctgaagcaa
    12961 aggacctaaa tttggaatta gccagtcatt tccagttaag actggaagaa acttcagagc
    13021 ggaaatggag cggaggggaa gaacgaaaga tcgagttgat acgtcttctt tcttcttatg
    13081 aacaagggat gcttctagac gagccaacaa cccatctaga tagaaaaagt attgatcgac
    13141 tgattgaaga gcttcgttat tattatggta cgctggtttt tgttagtcat gatcgctatt
    13201 ttctagatga gctagcatcg aaaatctggg aagtaaaaga cggagaaatc cgagagtttt
    13261 cggggaatta tagtgcctat ctcactcaaa aggaattgga gaaaaagact cagctacgag
    13321 aagcagagtc gatcatgaaa gagaaaaaac gattggaaaa atcgatccaa gaaaagaaaa
    13381 aacaagcgga aaagttggaa aaagtgtcca gtaaaaagaa aaagcaacaa atcagaccgg
    13441 atcggttgtc ttcctctaaa caaaaagaca gtgtacaaaa agccatccaa aagaatgcga
    13501 aaacattaga gagaagactc caaaaaatag gagaaacaac caagccgcag cagatgaaac
    13561 aaatccgttt tccagtacca aaatctcttg aactccacag ccgctatccc atcatgggac
    13621 aaaatgtcca attggaaaga agtgggagaa cattactggt aaatggtgat tttcagtttt
    13681 ctttaggtaa aaaaatcgcg attgtcggtg aaaatggttc aggtaagaca accttattag
    13741 aacatatccg caaacaagga gaaggaatcc ttctctctcc gaaagtaagc tttcaagtat
    13801 atcagcaaaa gggttatcaa atgacatctg aagaatccat cattcgtttt gtcatgagac
    13861 aaacagagtt ttcagaatcg cttgtccgta gtttgctgaa tcacttaggg tttgctcagg
    13921 aaactttgac gaaaccgtta tgtacattaa gtgggggaga agcgacccgt ctgacgattg
    13981 ctttgctttt tactaagcca agtaatgtgt tgctgttaga tgaaccgact aattttattg
    14041 atatggcaac gatcgaagct ttagagaagc taatgcaaat atatccggga acgattttgt
    14101 ttacttctca tgattcttac tttgtcgagc gtacggctga tgaagtttat gaaataaaag
    14161 ggcagaaaat aaaaaaagta cttacgagaa atttttaaat gtgctacgat gattttcgtg
    14221 acaaatttaa aggagtggta cagattgcct acaaataaaa aagaaggaat aatttttaca
    14281 acaatgatgt gttttttgat ggtcttgggg atgagcgcgt ataatttatg gctgcatcaa
    14341 gatcttcatt tatcaagttt gttgattggt ctagtgcctg gattcgtggt ggctttcatt
    14401 ttggatgtct tcatcatcgg tgtgctggcg aaaaaaattg cctttaaact accagtaaat
    14461 ccagaaagca aggtccaaat gatcttaact atttcatgct tgatggtttt aggaatggtg
    14521 acatgtatgt ctttattcgg tgtgatcatg gaacaaggaa tacctgatca attattctct
    14581 gcttatatga atgcttggaa aatgaatgtg attgccgctt taccgttgca gttgatcatc
    14641 gttggcccgc tttcaagaag tgtgctaaaa gcaattcaaa gtaatgaatg atggaacact
    14701 gttatttgaa aaaaggcctt ggcatgcttt ttgtcatagt ctcttgaatg cagttctaga
    14761 aaaatagtga tccgaacgat aggttttggc ctgtcgttcg gatcgctttt tcttttccaa
    14821 ctgtattgct cttttattga agataatttg ctcttcaata gatatttcta gaaaggttct
    14881 gtttatccct tactcaaaaa actgctgcat ttgttctctt acttgctgac accattggag
    14941 ttcctgctga caaagcataa ttctgcgctg gatcacaaca taacgtccaa attcttgttt
    15001 cttgtctagc gagaggtcat tcaatttttt ttgatttttt tgcatgattt tgttcagctg
    15061 ttgttctcta gtgaatagca gtccagtagc tgttgtttta tcgagcgtcg aaaaagcata
    15121 gatttttgct agaaattcat ctttttgcgt aggagcggga gtttcctctt tgatccattc
    15181 ctctacaaga gcacgtcctt catcagtcaa gtggtagatc tttttttgag agtgctcgtc
    15241 tttgtccaaa acggtcacat aaccctgctg gtctaacttg gcaagcgttg tatagatctg
    15301 actgtgatgg gcttcccaaa aaattgtgat cagctgcttc aattcatacc cagaacgtgg
    15361 tttggataaa agcacgcata ataatatata ggctaaagta ttcataaaaa tcctacctct
    15421 cgtcttattt tctttattat atcacagtaa agtttccacg ttttacatgt gcatatttac
    15481 atgtaaaata aatcatgtat gatgctaata gagagaaagg gatggaaata ttggagaatc
    15541 aaatagatat acaagaacaa acaaatgaag aaacaaaggg gaaaagttca gcgctagttg
    15601 tagcagctac ctgtatgatc gcttttatgg gagtgggtct agtagaccca atcttaaaaa
    15661 cgattgctgc acagttaaac gctacgccag ctgaaacgac cctgttattt actagttaca
    15721 tgttagtcac tggtgtggtg atgctattta caggtttctt atctagtcgg atcggtttga
    15781 aaaaaacatt gatgacagga ttgtttatca tcgttgtatt cgctggtctt ggcggattat
    15841 ctgggaatat cggaatgctg attgggttac gtgccggctg gggtgtcggg aatgctttat
    15901 ttgtctctac tgctttagca acgatcgtca gtattttagt tggtaacaca gaaaaagcaa
    15961 tcatgatgta tgaagcagca cttggctgcg gaatggctgt tggccctcta gtcggtgggg
    16021 tcttgggcag tggttcatgg cgttatccat tttttggggt agcatttttg atgttttgcg
    16081 gttttatagc cctagcggta cttttacctg aaactgagaa accaaagaga aaagtaggcc
    16141 tttgggaagg tgtcaaagcg ttaagcaatc ataaacttcg ttcagttgga ctaatcgcat
    16201 tgttatataa tttcggattc tttactttac ttgcgtatgc gccattttta ttgattggct
    16261 attctgaatt agaagtcggt tttgtatttt ttggctgggg tgtgcttctg gctattgctt
    16321 cgattttcgt tgcaccggct cttgagcgga agtttacgac ttatcggaca attttagcag
    16381 catttgtctt attcattatt tgtttgctgt tattaggagc tggaacttct atgccagtcc
    16441 ttgtaccgat cagcattgtg ttagcaggat ttttccaagg aattatcaat acactgttga
    16501 cgacgattgc tatggaaata ccaggtctgc aacgaaacgt tgcttcgtcc agctatagtt
    16561 ttgtccgctt tttcggtgga gctttagcac catttattgc aggtgtgatt ggtgaacata
    16621 ttggtgaaag ctatgcgttt tattttgcag gtgccattgt tcttatcagt gtatgttgta
    16681 tcatttatca ccgtaattat tttgctacaa atgaagaaga ataagaaatc agaggttgtg
    16741 aaaaagctgt cctgcatcaa gtcataagaa
//
LOCUS       DAYYEF010000208        10087 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.083, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000208 DAYYEF010000000
VERSION     DAYYEF010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.083"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            353..523
                     /locus_tag="ACHA1B_003056"
     CDS             353..523
                     /locus_tag="ACHA1B_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703718.1"
                     /translation="MKKFIYRVLENDEVVAIFNEQQYAQDFIAYEKTISDKQFEIEKV
                     DIADWLLQPREF"
     gene            537..1139
                     /locus_tag="ACHA1B_003057"
     CDS             537..1139
                     /locus_tag="ACHA1B_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703719.1"
                     /translation="MAKIGYARVSSKEQNLDRQLKALEGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNQIQIKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKKKGKFKGRQPKFKENDPRLQHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRSRYNVTVDQRKKQ"
     gene            1155..1832
                     /locus_tag="ACHA1B_003058"
                     /pseudo
     CDS             1155..1832
                     /locus_tag="ACHA1B_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_function: GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA];
                     GO_process: GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
     gene            2143..2640
                     /locus_tag="ACHA1B_003059"
     CDS             2143..2640
                     /locus_tag="ACHA1B_003059"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombinase"
                     /protein_id="HFM8703720.1"
                     /translation="MLFLRDGEIKATLTTMMNKLAFSHKLILEPLFKSVSQIDEESDR
                     ERMDAIDKLMEQLLEERNTLIALMSKGFLEPALFNQERNVLDSEIKNLTTEKTNLVTN
                     SASGVLRANEIKDLINYVSADNFNGDYTEELFEEFVVNIIVNSRDELTFNLKCGLSLK
                     EKVVR"
     gene            2641..3057
                     /locus_tag="ACHA1B_003060"
     CDS             2641..3057
                     /locus_tag="ACHA1B_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HFM8703721.1"
                     /translation="MAYIPYGYKIQDGVVTVDEKAAGQVKVFFEKYISGLSLTVAGEQ
                     AGIEKTHSVMGRILKNVNYLGNDTYPAIIDKEIFDKAEEVRDKRAKDLGRVVELAAFT
                     SPPPKERFKMKKADNKMPVDPFERAEYLYSLIESEE"
     gene            3077..4621
                     /locus_tag="ACHA1B_003061"
     CDS             3077..4621
                     /locus_tag="ACHA1B_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018659190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703722.1"
                     /translation="MVIPARKRVGSTAAKEKIKKLRVAAYCRVSTETEEQNSSYEVQV
                     SHYTEFIKKNNEWEFAGIFADDGISGTNTKKRDEFNRMIAECMDGNIDMVITKSISRF
                     ARNTLDCLQYIRQLKDKNISVYFEKENINTTDAKGEVLLTIMASLAQQESQSLSQNVK
                     LGLQYRYQQGKVQVNHKRFMGYTKDEDGNLTIVPEEAEIIKRIYREYLEGQSLVGIGR
                     ALEKDGILTAAGKPRWRPESVKKILQNEKYIGDALLQKTVTVDFLTKKRVKNEGHVPQ
                     YYVENSHEAIIPKELFLQAQEEIHRRSNIYTGEGKNKRIYSSKYALSAITFCGDCGDI
                     YRRVYWNIHGRKEFVWRCVTRIEQGPEVCKNRTVKEDELYGAVMTAINKLLAGGNNMI
                     KTLEENIHAVIGETTEYQISEINNSLEEKQKELIKLANKGQDYDHLADEIDELRDKRQ
                     ILLVEDASLSGENERINELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEGHFVIAFKS
                     GIEMEI"
     gene            4764..4988
                     /locus_tag="ACHA1B_003062"
     CDS             4764..4988
                     /locus_tag="ACHA1B_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HFM8703723.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGEEIKISNE"
     gene            5003..5872
                     /locus_tag="ACHA1B_003063"
     CDS             5003..5872
                     /locus_tag="ACHA1B_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HFM8703724.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            5853..6587
                     /locus_tag="ACHA1B_003064"
     CDS             5853..6587
                     /locus_tag="ACHA1B_003064"
                     /EC_number="2.1.1.222"
                     /EC_number="2.1.1.64"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008425 -
                     2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase
                     activity [Evidence IEA];
                     GO_function: GO:0061542 - 3-demethylubiquinol-n
                     3-O-methyltransferase activity [Evidence IEA];
                     GO_function: GO:0102208 - 2-polyprenyl-6-hydroxyphenol
                     methylase activity [Evidence IEA];
                     GO_process: GO:0006744 - ubiquinone biosynthetic process
                     [Evidence IEA];
                     GO_process: GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HFM8703725.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            6620..7528
                     /locus_tag="ACHA1B_003065"
     CDS             6620..7528
                     /locus_tag="ACHA1B_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HFM8703726.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            7525..8067
                     /gene="sat4"
                     /locus_tag="ACHA1B_003066"
     CDS             7525..8067
                     /gene="sat4"
                     /locus_tag="ACHA1B_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HFM8703727.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            8160..8954
                     /locus_tag="ACHA1B_003067"
                     /note="aph(3')-IIIa"
     CDS             8160..8954
                     /locus_tag="ACHA1B_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HFM8703728.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            9230..9361
                     /locus_tag="ACHA1B_003068"
                     /pseudo
     CDS             9230..9361
                     /locus_tag="ACHA1B_003068"
                     /inference="COORDINATES: protein motif:HMM:NF024804.4"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            9437..9930
                     /locus_tag="ACHA1B_003069"
                     /pseudo
     CDS             9437..9930
                     /locus_tag="ACHA1B_003069"
                     /inference="COORDINATES: protein motif:HMM:NF024676.4"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT         3548 a         1572 c         2207 g         2760 t
ORIGIN      
        1 acaagaagca ttttattcta gcttaatttg acaaatcata ctatgatacg tgtttgtttt
       61 tctgtgctgt ttagtgaatg attagcagaa atatagagag taagatttta attaattatt
      121 agggggagaa ggagagagta gcccgaaaac ttttagttgg cttggactga acgaagtgag
      181 ggaaaggcta ctaaaacgtc gaggggcagt gagagcgaag cgaacacttg atcttttaag
      241 ttgctatctt tttaaggtca atagagtata cttatttgtc ctaatatggt tttagcagta
      301 taattgactt ggtgaatagg tcatttaagt tgggcataat aggaggagta aaatgaaaaa
      361 atttatttat cgagttttag aaaatgacga agtggtggct atttttaatg agcaacaata
      421 tgcgcaagat tttatcgctt acgaaaagac aatttctgat aagcaatttg aaattgaaaa
      481 agtagatata gctgattggt tattgcaacc gagagaattt tagaggttgg ttgaaaatgg
      541 ctaaaattgg ttatgcacgt gtcagtagca aagaacagaa cttagataga caactgaaag
      601 cgttagaggg cgtttctaag gtcttttcag acaaattaag cggtcaatcg gtcgaacgcc
      661 cacaattaca agctatgctt aactatattc gtgaagggga tatagttgtt gttactgaat
      721 tagatcgatt aggacgaaat aataaagaat taacagaatt gatgaatcaa attcaaatta
      781 agggggcaac cctggaagtc ttaaatttac cctcaatgaa tggtattgaa gatgaaaatt
      841 taagacggct gattaataat ttagtgattg aattgtataa gtaccaagcg gaatctgaac
      901 gcaaacgaat taaagaacgc caagcccaag gaattgaaat tgctaagaaa aaaggaaaat
      961 tcaaagggcg acaacctaaa ttcaaagaaa atgatccacg tttacaacac gctttcgatt
     1021 tatttttgaa tggttgttcc gataaagaag ttgaagaaca aactggaatt aatcgccgaa
     1081 cgtttagaag gtatcgatca agatacaacg tgacagtaga tcaaagaaaa aaacaatgaa
     1141 aagagggata gttaatgagt acggttattt tagctgaaaa accaagccag gcattagcct
     1201 acgcaagtgc tttaaaacaa agcaccaaaa aagacggtta ttttgagatc aaagacccac
     1261 tatttacaga tgaaacgttt atcacctttg gttttgggca tttagtcgaa ttagcagaac
     1321 caggtcatta taacgaaaag tggcagaact ggaaacttga atctttgccg atttttcctg
     1381 atcgatacga ttttgaagtt gcaaaagata agggaaagca gtttaaaatt gttgctgaac
     1441 ttctcaaaaa ggcaaataca attattgtcg caacagatag cgacagagaa ggtgaaaata
     1501 tcgcctggtc gattatccat aaagcaaatg ccttttctaa agataaaacg tataaaagat
     1561 tatggatcaa tagcttagaa aaagatgtga tccgaagcgg ttttcaaaat ttgcaaccag
     1621 gaatgaatta ctatcccttt tatcaagaag cgcaaacacg ccaaattgcc gattggttga
     1681 tcggcatgaa cgcaagccct ttatatacct tgaatttaca acaaaaaggc gtacaaggta
     1741 cattttcatt aggacgtgta caaacaccga ctttatatct catttatcaa cgccaggaag
     1801 caatagaaaa ctttaaaaaa gaaccttttt tcctgaataa ttcatagttt tactaatagt
     1861 ctttcctaac attgatttaa tagtctttaa agtattctgc ttcatcaccc attaggtgat
     1921 gaaaaaagaa cccctttctg atttagcgga caaatacttt gacctaatct cagaagatat
     1981 aaaagaaaaa ataataaaat atccgattta tactttgtat aaagaactaa agtagttagc
     2041 aaatcattta cagcaaatca ctatgttcca cataccattt tacatactta ccttatccac
     2101 gacacatgtt gagatagtat cgaagataaa gaaagttgct ccatgttgtt tttgcgagat
     2161 ggggaaatca aagccacatt gacaaccatg atgaataagc ttgctttcag tcataagcta
     2221 atcctagaac cacttttcaa gtcagttagc caaatcgatg aagaaagcga ccgtgaaaga
     2281 atggacgcta ttgataagct aatggagcaa ctattggaag aacgcaatac ccttattgca
     2341 ctgatgtcca aaggtttcct agaacctgct ctttttaatc aggaacgaaa tgttttagat
     2401 agtgagatta aaaatcttac taccgaaaaa acaaacctgg taacgaactc tgcgagtggg
     2461 gttttgcgag caaacgagat aaaggacctc attaattatg tgtcagcaga taattttaat
     2521 ggtgactaca cggaagaact atttgaagaa tttgtagtga acatcattgt aaattccagg
     2581 gatgagctga cattcaattt gaaatgcggt ctttccctga aagaaaaggt ggtgagataa
     2641 atggcatata ttccatatgg atacaaaatt caagatggag tggttactgt cgatgaaaag
     2701 gcagcaggtc aagtaaaggt attctttgag aaatacatat caggactatc ccttacagtg
     2761 gctggcgaac aggcaggtat tgaaaagaca cattctgtga tggggcgcat tttgaaaaac
     2821 gtcaactacc ttggaaatga tacgtatcca gcaattattg ataaagagat atttgataaa
     2881 gctgaagaag ttagagataa acgtgcaaag gatttaggac gagtggtaga gcttgccgct
     2941 ttcacctctc cccctcccaa agaacgattc aaaatgaaaa aggcagataa taagatgcca
     3001 gtggatcctt ttgaacgagc agaatactta tacagtctga tagaaagcga ggaataaagt
     3061 gacagagaaa aatataatgg ttattcctgc tcgtaaaaga gtaggaagta cagccgcaaa
     3121 agaaaagata aagaaacttc gtgttgctgc ctattgccgt gtttctacag aaacagaaga
     3181 acaaaattct agctatgagg ttcaggtctc acactataca gagtttataa agaaaaataa
     3241 tgaatgggag tttgctggca tctttgcaga tgatggtatc tctggtacga acactaaaaa
     3301 gcgtgacgaa tttaatcgca tgattgcaga gtgtatggac ggtaacatcg acatggttat
     3361 tacaaaatcc atcagccgat ttgcgcgtaa caccctagac tgccttcaat acattagaca
     3421 gctcaaggat aagaacatat cagtttattt tgagaaagag aacatcaaca ccacggatgc
     3481 caaaggtgag gttttgctga ctattatggc atctttggca cagcaggaaa gccagagcct
     3541 ttcacaaaac gttaagcttg ggctacagta ccgataccaa caaggaaagg tgcaggtcaa
     3601 ccataagcga tttatgggct acacgaaaga tgaagatgga aatttaacta ttgtccccga
     3661 agaagctgag attatcaaac gcatctaccg agaatacctt gagggtcaga gtctagtggg
     3721 cattggtcga gcccttgaaa aggatggtat tttaacagca gcgggaaaac caagatggcg
     3781 accagaatca gttaagaaga tacttcaaaa cgaaaaatac atcggagatg cccttctgca
     3841 aaagactgtc acagtagatt ttctgaccaa gaaacgagtg aaaaatgaag ggcatgttcc
     3901 ccaatattat gttgaaaata gccatgaagc gattattcct aaagagttat ttttgcaggc
     3961 gcaagaagaa attcatcgga gaagcaatat ctacacagga gaaggcaaga acaaaagaat
     4021 ttacagtagc aagtacgctt taagtgccat caccttctgt ggagattgtg gcgatattta
     4081 tagacgggtc tattggaata tccacggaag aaaagaattt gtctggcgat gcgtgactag
     4141 aatcgagcaa ggtcctgaag tttgtaagaa ccgaaccgta aaagaagatg aactttatgg
     4201 tgcagtaatg actgcgatta ataagctact tgcaggtggg aacaatatga taaagacact
     4261 ggaagagaat attcatgctg tgattggcga aaccacagaa taccaaattt cagagattaa
     4321 caactcacta gaggaaaaac aaaaagaact aatcaagctg gcgaacaagg gtcaagacta
     4381 tgaccactta gcagatgaga ttgatgagct gagagacaag cgacagatcc ttttagtaga
     4441 agatgcctcc ctcagtggcg agaacgagcg aatcaatgag ctgattgaat ttatccgcaa
     4501 gaacaaattc cgcaccttag aatatgatga taagcttgta aggaagataa tccagagcgt
     4561 tacagtctat gaaggccact tcgtcatagc cttcaaatct ggcatcgaaa tggaaatatg
     4621 aaaaccagaa gtaaatagcc catgactcta cagtagagtt gtgggttttc ttttgcttgc
     4681 tgattataat aatattttaa taactattgt gtttatcaac caaatggttt ataatattct
     4741 tagcgtaaac ttggaggtgc tgtatgacta cggcagaaat gattaaagaa ctgtgtgagc
     4801 aaatgaatat aagtgtttcc gaacttgcta gacgtattgg ccagactcca cagaatttca
     4861 ataaaaaatt acaacgagaa acagtaacct tggatgagtt gaaggccatt gctgatgtgc
     4921 taggtgtcaa gtttgtgcag gcatttattt taccagatgg agaagaaata aaaatatcta
     4981 acgaataaag gaggatgttt atatggtagg taatgttatt caaatagtaa cagagaaatt
     5041 atcatctttg ccttttatag aaggcatcgt attagggggc tcacgtgcaa gaggcaccca
     5101 tacagaaaat tctgatatag atatcggaat ctattacaat tcagactcat ttgacctgac
     5161 agcgattaat caaattgcta cagagttgga tgatgagaat agaaacaacc ttgttgtacc
     5221 tcccggagcg tggggtgatt gggttaatgg cggtggatgg ttagttataa acgggtgtca
     5281 tgttgacttg atattacgtg atataaaacg ggtggaacaa ataatcaaag atacggagca
     5341 aggaattgtt actgccaatt atcagaccgg gcatccccat ggttatataa gtgctatgta
     5401 tcgtggagaa ttagcgatta gtaaaatact atatgctaag aacgaaagct tatgcgaatt
     5461 aaaaaagcag gcagaaattt accctactgc tctaaagaaa agcttgatga acttttttat
     5521 atttgaagct gaattctctt taatgtttgt aaaagcaaat gcgggggcag aggataaata
     5581 ttatattgca ggccatgttt ttcgtattat ttcatgctta aatcaagtac tatttgcatg
     5641 taataatgct tattgcatta acgaaaagaa agctataaaa ctgcttgaaa cttttgaata
     5701 taaacctgaa aaatatgccg aaagagttaa tcatattttt gaagtactcg gtctttctct
     5761 ttttgaatgc tacgacatga ccgagaaact ttataaagaa gtgaatgaaa ttgtatcgga
     5821 gataaataac tttttaaacg aggagagttc agatgaaaga aaacaaatat gatgataata
     5881 tattttttca aaaatacagt caaatgagtc gctcgcagaa aggactggct ggtgcgggag
     5941 aatgggagac tttgaaaaag atgctacctg attttaaggg taagcgtgtg cttgatttag
     6001 gatgcggcta tggatggcac tgtatatatg cgatggaaaa cggtgcttcc tctgtagtag
     6061 gtgttgatat ttctcataaa atgctcgaag tagcaaaagg aaaaacccat tttccacaga
     6121 ttgaatatga atgctgtgcc atagaagatg tggatttccc agaggagagc tttgatgtaa
     6181 tactaagttc gcttgcgttt cattatgtag cagactatga gaatttaata aaaaagatat
     6241 ataggatgct gaaggctggt ggcaatttag tttttacagt tgaacatcct gtttttactg
     6301 ctcatggaac acaagactgg tattataacg aaaaaggaga aatactgcat ttcccggtgg
     6361 acaattatta ttatgagggc aaacggacag ctatgttttt ggaagaaaag gttacaaaat
     6421 atcatagaac actgaccaca tatctaaata cactgctttc aaatagtttt ataataaatc
     6481 agattgtgga gccacagccg ccagagaaca tgatggatat tccggggatg gcggatgaaa
     6541 tgcgacgccc aatgatgctg attgtatcgg caaaaaagaa gatgtaataa tatagaaaaa
     6601 ataaacgagg agtatgtaaa tgagatcaga aaaagaaatg atggatttag tactttcttt
     6661 agcagaacag gatgaacgta ttcgaattgt gacccttgag gggtcacgcg caaatattaa
     6721 tatacctaaa gatgaatttc aggattatga tattacatat tttgtaagtg atatagaacc
     6781 gtttatatct aatgatgact ggcttaatca atttgggaat ataataatga tgcaaaagcc
     6841 ggaggatatg gaattattcc cacctgaaga aaagggattt tcctatctta tgctatttga
     6901 tgattacaat aaaattgatc ttaccttatt gcccttggaa gagttagata attacctaaa
     6961 gggcgataaa ttaataaagg ttctaattga taaagattgt agaattaaaa gggacatagt
     7021 tccgactgat atagattatc atgtaagaaa gccaagcgca agggagtatg atgattgctg
     7081 caatgaattt tggaatgtaa caccttatgt tattaaagga ttgtgccgta aggaaatttt
     7141 atttgctatt gatcatttta atcagattgt tcgccatgag ctgctgagaa tgatatcatg
     7201 gaaggtcggc atcgaaacag gctttaaatt aagtgtaggc aagaactata agtttattga
     7261 aaggtatata tccgaggatt tgtgggagaa acttttgtcc acctaccgga tggattccta
     7321 tgaaaacata tgggaagcat tatttctatg ccatcaattg ttcagggcgg tatccggtga
     7381 ggtggcggaa aggcttcatt atgcctatcc ggagtatgat aggaatataa caaaatatac
     7441 cagggacatg tataaaaaat acactggtaa aaccggctgc ctggatagca catatgccgc
     7501 tgatatagaa gagaggcggg aacagtgatt acagaaatga aagcagggca cctgaaagat
     7561 atcgataaac ccagcgaacc atttgaggtg ataggtaaga ttataccgag gtatgaaaac
     7621 gagaattgga cctttacaga attactctat gaagcgccat atttaaaaag ctaccaagac
     7681 gaagaggatg aagaggatga ggaggcagat tgccttgaat atattgacaa tactgataag
     7741 ataatatatc tttactacca agacgataaa tgcgtcggaa aagttaaact gcgaaaaaat
     7801 tggaaccggt acgcttatat agaagatatc gccgtatgta aggatttcag ggggcaaggc
     7861 ataggcagcg cgcttatcaa tatatctata gaatgggcaa agcataaaaa cttgcatgga
     7921 ctaatgcttg aaacccagga caataacctt atagcttgta aattctatca taattgtggt
     7981 ttcaaaatcg gctccgtcga tactatgtta tacgccaact ttgaaaacaa ctttgaaaaa
     8041 gctgttttct ggtatttaag gttttagaat gcaaggaaca gtgaattgga gttcgtcttg
     8101 ttataattag cttcttgggg tatctttaaa tactgtagaa aagaggaagg aaataataaa
     8161 tggctaaaat gagaatatca ccggaattga aaaaactgat cgaaaaatac cgctgcgtaa
     8221 aagatacgga aggaatgtct cctgctaagg tatataagct ggtgggagaa aatgaaaacc
     8281 tatatttaaa aatgacggac agccggtata aagggaccac ctatgatgtg gaacgggaaa
     8341 aggacatgat gctatggctg gaaggaaagc tgcctgttcc aaaggtcctg cactttgaac
     8401 ggcatgatgg ctggagcaat ctgctcatga gtgaggccga tggcgtcctt tgctcggaag
     8461 agtatgaaga tgaacaaagc cctgaaaaga ttatcgagct gtatgcggag tgcatcaggc
     8521 tctttcactc catcgacata tcggattgtc cctatacgaa tagcttagac agccgcttag
     8581 ccgaattgga ttacttactg aataacgatc tggccgatgt ggattgcgaa aactgggaag
     8641 aagacactcc atttaaagat ccgcgcgagc tgtatgattt tttaaagacg gaaaagcccg
     8701 aagaggaact tgtcttttcc cacggcgacc tgggagacag caacatcttt gtgaaagatg
     8761 gcaaagtaag tggctttatt gatcttggga gaagcggcag ggcggacaag tggtatgaca
     8821 ttgccttctg cgtccggtcg atcagggagg atatcgggga agaacagtat gtcgagctat
     8881 tttttgactt actggggatc aagcctgatt gggagaaaat aaaatattat attttactgg
     8941 atgaattgtt ttagtaccta gatttagatg tctaaaaagc tttaactaca agctttttag
     9001 acatctaatc ttttctgaag tacatccgca actgtccata ctctgatgtt ttatatcttt
     9061 tctaaaagtt cgctagatag agttctatat tagagatgta aagagttttg gtgaagaggt
     9121 ttgtgagtat ggcttttata accagggtgc aatgagaagc actaacagca gctagcttaa
     9181 gaacgcatag gatatacttt ttatggaagt cacagaggag gaataaaatt tgaacaggat
     9241 taacagagta acctctattc ttattcagct gcaatcaaaa aaaataattc ctgccaaaga
     9301 aattgcacag cgatttaata taagcttaag gacagtttac agagatatcc ggacacttga
     9361 agaagccgga ataccaattg gatctgaggc cggaaaagga tattttcttg tagagggctt
     9421 cctacttccg ccggtaatgt ttacagcggc ggaagtgggt gcattgatta cagcagggaa
     9481 atttttaaat tgccatggag atgaatcatt tataaaggat tttgattcag ctatgtataa
     9541 aatcaaatct attttgaagc atggtgaaaa aaactatgca caggagttgg agaacagtat
     9601 taacgtgtac agcacatctg gacagaaaaa tacattggcg gataacgtta ttgcagcaat
     9661 tcagactgca atctgcaata aaagggtaat atcaattcaa tatcctgcat caggagggca
     9721 agaaccggaa agcagaatga tagagcctat atcactgggg ttttatgaac agaactggta
     9781 cttaatcggt tttgcaggct aagaaatgaa tataggaatt ttcgtgtgga tcggattaaa
     9841 agcatttgca tagaagaaga gctctgtcaa agccatgatg gctctttgga acaaatatta
     9901 aaacaaatgc tttcatataa aaaactatat gccctacaat gccgttgtaa aaattgggga
     9961 aaagggatat attgatttta tatctttctc aaaataaata taaaagccct ttaaagaggg
    10021 cttttatata ttaatcacaa atcacttatc acaaatcaca agtgattaat cacaaatcac
    10081 ttgtgat
//
LOCUS       DAYYEF010000209         5851 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.102, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000209 DAYYEF010000000
VERSION     DAYYEF010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5851
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.102"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            322..1014
                     /locus_tag="ACHA1B_003070"
     CDS             322..1014
                     /locus_tag="ACHA1B_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HFM8703729.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            1341..1838
                     /gene="dfrG"
                     /locus_tag="ACHA1B_003071"
     CDS             1341..1838
                     /gene="dfrG"
                     /locus_tag="ACHA1B_003071"
                     /EC_number="1.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HFM8703730.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(1910..3862)
                     /locus_tag="ACHA1B_003072"
     CDS             complement(1910..3862)
                     /locus_tag="ACHA1B_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HFM8703731.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3869..4105)
                     /locus_tag="ACHA1B_003073"
     CDS             complement(3869..4105)
                     /locus_tag="ACHA1B_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703732.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            4507..4797
                     /locus_tag="ACHA1B_003074"
     CDS             4507..4797
                     /locus_tag="ACHA1B_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HFM8703733.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(5069..5418)
                     /locus_tag="ACHA1B_003075"
                     /pseudo
     CDS             complement(5069..5418)
                     /locus_tag="ACHA1B_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741963.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            5511..5813
                     /locus_tag="ACHA1B_003076"
                     /pseudo
     CDS             5511..5813
                     /locus_tag="ACHA1B_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF6056 family protein"
BASE COUNT         1997 a          925 c         1010 g         1919 t
ORIGIN      
        1 tttcataggt aaaagaagca tgacaattta tgacaaatcc gcgttttttg taataaatac
       61 agtaatctat gaaatgaaaa gggttacgtt taataaaact tgcttttttg tttttgttca
      121 ccataaatat ttatttaaga aagtattaac ctgcattttt ctctataaaa aagatttttt
      181 aaatagataa aaaaggagga ttaaatgagt atttgatagt atttatatta aaattacata
      241 tgtaatttaa aaacgcttga cattgtgttt gagatcactt acttttagca tgtaaaagta
      301 ttggattaag gagctatgca aatgaaaaag aaatttatta ctggtgggat tgtcgttgca
      361 tttctatgtc taattggcta cacaggcacg cggtacgcaa atgaaattat tttgtggggt
      421 ggagagacag atattgatac aatcaatgag aatctgacac agcttgatca tacattgaca
      481 gataaagagc aagcgattac agatcttacc gctcgactag cacaaaaaga acagacattg
      541 caagattcaa aggcagatgt ccaagaatac caaacaaaag taaatgaatt agaaaaccaa
      601 aaaaatcaat cggcagcaga aaaacaaaac ttagaaagtc aattagtcag caaggatgca
      661 caactacaaa gcaaacaaaa tgaaatcaat gtcaaactag atgagatcaa ccaaaaaaat
      721 gatgaaatca atcatctgaa tgcagattgg acagcaagac tacaagaagc acaagcaaaa
      781 ctttcagaat tacaaaatac tgtaaatggt ttgaatcaac aaatcgcaac actgacacaa
      841 gaaaaaacaa atgtagaaac tcagttaaca gatacacaaa agaaattaga cgaagcaact
      901 gctgaaaact caagcttgaa acaatatatt caaaagttag aaaaagcaaa agatgaagtg
      961 gaagatacag ctgataaatc tcagcaaatt gttgaagaac atttgcgtaa ataatctttc
     1021 ttaacaagta aacctaaatt agtaaagaag caacagtaat ctatactaag tagttcagtt
     1081 ttggagtaca aaatgacaaa atgtacttca aaatggacta cttttttcat tttaacttac
     1141 ataccaaatt acatacaaaa tgatttataa aatgcaattg aaaatgataa ttgaatgaaa
     1201 atttgtgatt ttgtggtatt atgataatat aacttataga aaaaattgct tattcaacta
     1261 acgggcagga taatgagaaa aggttttttg atagaaataa gaaattagat ggtaaattag
     1321 ttaaaaaggc tgtgttataa atgaaagttt ctttgattgc tgcgatggat aagaatagag
     1381 tgattggcaa agagaatgac attccttgga ggattcccaa ggactgggaa tatgttaaaa
     1441 atactacaaa gggacatccg ataatattag gtaggaagaa ccttgaatca atcggaagag
     1501 ccttacctga cagaagaaat attattctga cgagagataa ggggtttacc tttaatggtt
     1561 gtgaaattgt tcattcaata gaagatgttt ttgagttatg taaaaacgaa gaagaaattt
     1621 ttattttcgg aggagaacag atttataatt tgtttttccc ttatgttgag aaaatgtaca
     1681 tcacaaaaat acatcatgaa ttcgaaggag atactttttt tccagaagtg aattatgagg
     1741 aatggaatga ggtatttgcc caaaaaggga taaagaatga taaaaatccg tataactact
     1801 attttcatgt atatgaaaga aaaaacttat tgagttaacg ggtgcgttaa ttgaagaaga
     1861 acagtaaaga taaagcacaa gagcttggga ttactccaag ctctttttgt catttgaaat
     1921 aaattatatc tttccaatca aattgtttat ctgtaatccc taatctttga gcaggtgtca
     1981 aaaccttttt atccgctgat ttaaaagggc gacaaaagtt gtagtaagtt cttagaattg
     2041 taatcgcaaa ttgagcatac ttcggattga agttagcgta aatatagctc ttcttatcac
     2101 cacgagctgt tgttaatggt ctttcaagag atgatatata acgtcttatc tgttgaataa
     2161 agctattggt cgaatggtca ttaacattta atagcatctt tgcgatttcg tttggttcca
     2221 gagcagataa atccgttcta caatcaactg aataaaatcc tttatcctta gtggctaatg
     2281 gatgtttgat agggttatcg gcatatttgc gatatctttc tccatcttta ctaatagcct
     2341 cttcgtggaa ttgatgactt gttagtaatt cagttagata atgagatgcc aaagtccgta
     2401 gaaactttgt tttgaatcct ctgatatctc cccaatcgag cagttctgct tttgcttgtc
     2461 cgaattcttt taagcattgt tttctgcttt tcgtcttgtt aacttggcaa ataaaatgat
     2521 gtgcatcgct caaccttaat tctttcgtga atactctata aaaggcgttt ctaatagaga
     2581 agtcatcatc actaatcatt cgccattcgt cggcattaac catttgttta attaaccaat
     2641 agtgagcagt tgtagtataa ggagcatcaa catttaaacc atcgacaaat ctactcctat
     2701 tagtaatttt ccctaattcg tgaagataag cattcctatt ttcgctatcg ttagcggatg
     2761 gttcttgtgg ataataagac caatctaacc tatcattttt acgactaaaa gtattgagat
     2821 ggtcttcttt gaattttctt gtatcttcat ttaattcatc cattgaaata ttccaatcat
     2881 aggcaacatc agaacggaac acatatcttg ataagacctc agcagataca actatatacg
     2941 tttgcatatt aaggtcttca aaccccgtat atttctttga accttgtcct ttcttacgga
     3001 cgttatttag gtagtagtgc atcttgtccg tattaagcca catctcgtta aatttctttg
     3061 tttgaagggg ttgtgtctca tatcgttcta aaaactccaa acaacgccta tacagccact
     3121 ccagcttatg atagtaggtt ccaactccaa ttcctaaaat atcacaagta cgactgactg
     3181 aaacccttcc aacaaccatc ttagcgaaca ttggaagaat ggtgttcttt tgttggtgat
     3241 aagtagtggt ttcttctctt tttggtagaa cattagtgaa cttcttacac gccttacatt
     3301 gatagcgttg agatttgccc ctacttttcc cccttttgta aaattgcttc ggctcattga
     3361 atggggttga ttcttcttcc gagcagcctt ctttatgaaa ttgataatct ggctcaacat
     3421 cttggatgct attgatttct ataaggcgtt taatttcttc aacaacagac caattagata
     3481 aaggggttac tgtacagttt tgcgatacac ctctgccaat aggattgtca ttgcagtaca
     3541 tacctttatg acctttatct ttggaactac cagtcatttt atatcgactt ggtttccctt
     3601 ttacatcttt gaatttgtgc tgttctttcc caaaattaca acaaaacgga ttgatgcagt
     3661 aattatattg aatgggatat tcagaaccgt tccatttaaa agacgttggc aagaacaaca
     3721 ttttgttata ccttgttgca aatcgttttg gagttaataa atcatattgt ttagccctat
     3781 cttttaattc ttcgtttgaa atcggaattt taacatctac aatttcatct tccttcgtgg
     3841 ctaatctttt aagcttggtc attgtctatc aacccactct atctttgata cccatttttt
     3901 caacaatccg cttattactt cgcttgttgg caatccattc aataaacttc ttatcgtcta
     3961 aaatgttcaa taagaattca tccactgctt cgctttcagt acgctctgca tattcagcgt
     4021 attgcttaac tatcaccctt acttgctctg atatttccca atccacagac ttagcgttct
     4081 tattttttgg ctcaagaaat tgcataggaa aatgcacccc tttttgctta gtaaattgta
     4141 accattttaa cacaccaatt tgcattccta caataattat ttcacgttcg catttttata
     4201 tacattttaa cttacatttt gtggtgtaaa ttaacaacaa acgttgattt aacaataaaa
     4261 aacgagtatc aaattcagtt gcaatttgat actcatttag gtttacattt tcactttttg
     4321 tactccaaaa ctgaactact taaatctata ctgctgcctc ttttttttag tacatgtcct
     4381 tcatcttcgc aggaagtgcc aatatgattt taagaaaggt aatagacaaa aagtcaaaaa
     4441 gataaaacag agtttcttct ttacaaaggg aatgtatgtt cgtataatgg tattgaggtg
     4501 aaggttatgg agaaaaaata tggaacagta gataagatcc gtactttgca agttagtgcc
     4561 agaccgttga tccgtttcag tttaaatggg gtcaattgtt tgattgcttc ccatagtttg
     4621 aacttcctag ctgaagtaga cgaagggatg aagttagtcg ttacaggtta ttataataat
     4681 agaaagcaat ttgttgtgag atcctatcat gtgttaggga aacccaaaat tgtggtagaa
     4741 tatgagaaaa gtctataccc aagaaaaaag gtccgacaag atgaaagaat aaactagaaa
     4801 acaagcggct gagacaaaaa tgtcctagcc gcttgttttg gaaagatgga tgcagacgat
     4861 gggatttgaa cccacacgag catacgctca caagaacctc aatctatata taactacatg
     4921 tatttaagta tttgtgatga atcactaaac tttccaaact catttgaggg atattgctta
     4981 aagattgaac agatcaattc gaagccctat tagtattcgc tcaatggggg gatcagaggc
     5041 cataaaaaga gactagtcat tactagtctc aggtagtgga attgtaggat tttaaacgtt
     5101 cctggagagt accggtatgt aactcgaaga ggtgattatc atagtcgtaa aagtaaattg
     5161 aagaagcctc gcctttcaca cgagaacgtc ctggttcgac agttaaacct aacatttgga
     5221 tttttgagac aaacgaatct atatcttgtt cgtcaatttt aaaagcaata tgattgtatg
     5281 tctttggcag tttattcgac gaattctgca ttactgcaat ccataggtcc ttaactaaga
     5341 aaaatttttc tggatataat gaaaattttt ttgttgacta tcgtagattt cttttgcatc
     5401 aaataaggta tttaacaatt aagtatttaa aagataactt ttaagttatc tttaagtaat
     5461 gcttaaagct atgttatact ctattaggaa atataagaag gagtataaaa atgaacaaac
     5521 ataatagaaa aataacgaat aacaaagaac tgatcttgtt actaataggg atttggggta
     5581 tctttttact ctttaatatg tatatgccga ctatgagagc ggatgacgta gtttatgcaa
     5641 gtagattaga tgaacttggc tatttgggtg cttcgataga acattataag acatggagtt
     5701 caagaattat tatagaacta ttcttaatgt tcttttctaa acactttatg ctatggaaat
     5761 tattaaattc tacgattatg ttaggaattg tagtattact ttgcaagtat gttgagagta
     5821 taaaatattt tgtgtaaatg aaaaaatcca t
//
LOCUS       DAYYEF010000210         5116 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.109, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000210 DAYYEF010000000
VERSION     DAYYEF010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5116
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.109"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            244..1212
                     /locus_tag="ACHA1B_003077"
     CDS             244..1212
                     /locus_tag="ACHA1B_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HFM8703734.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1205..2236
                     /gene="vanA"
                     /locus_tag="ACHA1B_003078"
     CDS             1205..2236
                     /gene="vanA"
                     /locus_tag="ACHA1B_003078"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_component: GO:0005737 - cytoplasm [Evidence IEA];
                     GO_function: GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA];
                     GO_function: GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HFM8703735.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2242..2850
                     /locus_tag="ACHA1B_003079"
     CDS             2242..2850
                     /locus_tag="ACHA1B_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HFM8703736.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3278..4189
                     /locus_tag="ACHA1B_003080"
     CDS             3278..4189
                     /locus_tag="ACHA1B_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HFM8703737.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4342..4827
                     /gene="vanZ-A"
                     /locus_tag="ACHA1B_003081"
     CDS             4342..4827
                     /gene="vanZ-A"
                     /locus_tag="ACHA1B_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HFM8703738.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT         1626 a          882 c         1140 g         1468 t
ORIGIN      
        1 tgctggtgtc atccaccaac atcaaaaagt atagagccat aattttttag gaaaatctca
       61 aggttatctt tactttttct taggaaatta acaatttaat attaagaaac ggctcgttct
      121 tacacggtag acttaatacc gtaagaacga gccgttttcg ttcttcagag aaagatttga
      181 caagattacc attggcatcc ccgttttatt tggtgccttt cacagaaagg gttggtctta
      241 attatgaata acatcggcat tactgtttat ggatgtgagc aggatgaggc agatgcattc
      301 catgctcttt cgcctcgctt tggcgttatg gcaacgataa ttaacgccaa cgtgtcggaa
      361 tccaacgcca aatccgcgcc tttcaatcaa tgtatcagtg tgggacataa atcagagatt
      421 tccgcctcta ttcttcttgc gctgaagaga gccggtgtga aatatatttc tacccgaagc
      481 atcggctgca atcatataga tacaactgct gctaagagaa tgggcatcac tgtcgacaat
      541 gtggcgtact cgccggatag cgttgccgat tatactatga tgctaattct tatggcagta
      601 cgcaacgtaa aatcgattgt gcgctctgtg gaaaaacatg atttcaggtt ggacagcgac
      661 cgtggcaagg tactcagcga catgacagtt ggtgtggtgg gaacgggcca gataggcaaa
      721 gcggttattg agcggctgcg aggatttgga tgtaaagtgt tggcttatag tcgcagccga
      781 agtatagagg taaactatgt accgtttgat gagttgctgc aaaatagcga tatcgttacg
      841 cttcatgtgc cgctcaatac ggatacgcac tatattatca gccacgaaca aatacagaga
      901 atgaagcaag gagcatttct tatcaatact gggcgcggtc cacttgtaga tacctatgag
      961 ttggttaaag cattagaaaa cgggaaactg ggcggtgccg cattggatgt attggaagga
     1021 gaggaagagt ttttctactc tgattgcacc caaaaaccaa ttgataatca atttttactt
     1081 aaacttcaaa gaatgcctaa cgtgataatc acaccgcata cggcctatta taccgagcaa
     1141 gcgttgcgtg ataccgttga aaaaaccatt aaaaactgtt tggattttga aaggagacag
     1201 gagcatgaat agaataaaag ttgcaatact gtttgggggt tgctcagagg agcatgacgt
     1261 atcggtaaaa tctgcaatag agatagccgc taacattaat aaagaaaaat acgagccgtt
     1321 atacattgga attacgaaat ctggtgtatg gaaaatgtgc gaaaaacctt gcgcggaatg
     1381 ggaaaacgac aattgctatt cagctgtact ctcgccggat aaaaaaatgc acggattact
     1441 tgttaaaaag aaccatgaat atgaaatcaa ccatgttgat gtagcatttt cagctttgca
     1501 tggcaagtca ggtgaagatg gatccataca aggtctgttt gaattgtccg gtatcccttt
     1561 tgtaggctgc gatattcaaa gctcagcaat ttgtatggac aaatcgttga catacatcgt
     1621 tgcgaaaaat gctgggatag ctactcccgc cttttgggtt attaataaag atgataggcc
     1681 ggtggcagct acgtttacct atcctgtttt tgttaagccg gcgcgttcag gctcatcctt
     1741 cggtgtgaaa aaagtcaata gcgcggacga attggactac gcaattgaat cggcaagaca
     1801 atatgacagc aaaatcttaa ttgagcaggc tgtttcgggc tgtgaggtcg gttgtgcggt
     1861 attgggaaac agtgccgcgt tagctgttgg cgaggtggac caaatcaggc tgcagtacgg
     1921 aatctttcgt attcatcagg aagtcgagcc ggaaaaaggc tctgaaaacg cagttataac
     1981 cgttcccgca gacctttcag cagaggagcg aggacggata caggaaacgg caaaaaaaat
     2041 atataaagcg ctcggctgta gaggtctagc ccgtgtggat atgtttttac aagataacgg
     2101 ccgcattgta ctgaacgaag tcaatactct gcccggtttc acgtcataca gtcgttatcc
     2161 ccgtatgatg gccgctgcag gtattgcact tcccgaactg attgaccgct tgatcgtatt
     2221 agcgttaaag gggtgataag catggaaata ggatttactt ttttagatga aatagtacac
     2281 ggtgttcgtt gggacgctaa atatgccact tgggataatt tcaccggaaa accggttgac
     2341 ggttatgaag taaatcgcat tgtagggaca tacgagttgg ctgaatcgct tttgaaggca
     2401 aaagaactgg ctgctaccca agggtacgga ttgcttctat gggacggtta ccgtcctaat
     2461 cgtgctgtaa actgttttat gcaatgggct gcacagccgg aaaataacct gacaaaggaa
     2521 agttattatc ccaatattga ccgaactgag atgatttcaa aaggatacgt ggcttcaaaa
     2581 tcaagccata gccgcggcag tgccattgat cttacgcttt atcgattaga cacgggtgag
     2641 cttgtaccaa tggggagccg atttgatttt atggatgaac gctctcatca tgcggcaaat
     2701 ggaatatcat gcaatgaagc gcaaaatcgc agacgtttgc gctccatcat ggaaaacagt
     2761 gggtttgaag catatagcct cgaatggtgg cactatgtat taagagacga accatacccc
     2821 aatagctatt ttgatttccc cgttaaataa acttttaacc gttgcacgga caaactatat
     2881 aagctaactc tttcggcagg aaacccgacg tatgtaactg gttcttaggg aatttatata
     2941 tagtagatag tattgaagat gtaaggcaga gcgatattgc ggtcattatc tgcgtgcgct
     3001 gcggcaagat agcctgataa taagactgat cgcatagagg ggtggtattt cacaccgccc
     3061 attgtcaaca ggcagttcag cctcgttaaa ttcagcatgg gtatcactta tgaaaattca
     3121 tctacattgg tgataatagt aaatccagta gggcgaaata attgactgta atttacgggg
     3181 caaaacggca caatctcaaa cgagattgtg ccgtttaagg ggaagattct agaaatattt
     3241 catacttcca actatatagt taaggaggag actgaaaatg aagaagttgt tttttttatt
     3301 gttattgtta ttcttaatat acttaggtta tgactacgtt aatgaagcac tgttttctca
     3361 ggaaaaagtc gaatttcaaa attatgatca aaatcccaaa gaacatttag aaaatagtgg
     3421 gacttctgaa aatacccaag agaaaacaat tacagaagaa caggtttatc aaggaaatct
     3481 gctattaatc aatagtaaat atcctgttcg ccaagaaagt gtgaagtcag atatcgtgaa
     3541 tttatctaaa catgacgaat taataaatgg atacgggttg cttgatagta atatttatat
     3601 gtcaaaagaa atagcacaaa aattttcaga gatggtcaat gatgctgtaa agggtggcgt
     3661 tagtcatttt attattaata gtggctatcg agactttgat gagcaaagtg tgctttacca
     3721 agaaatgggg gctgagtatg ccttaccagc aggttatagt gagcataatt caggtttatc
     3781 actagatgta ggatcaagct tgacgaaaat ggaacgagcc cctgaaggaa agtggataga
     3841 agaaaatgct tggaaatacg ggttcatttt acgttatcca gaggacaaaa cagagttaac
     3901 aggaattcaa tatgaaccat ggcatattcg ctatgttggt ttaccacata gtgcgattat
     3961 gaaagaaaag aatttcgttc tcgaggaata tatggattac ctaaaagaag aaaaaaccat
     4021 ttctgttagt gtaaatgggg aaaaatatga gatcttttat tatcctgtta ctaaaaatac
     4081 caccattcat gtgccgacta atcttcgtta tgagatatca ggaaacaata tagacggtgt
     4141 aattgtgaca gtgtttcccg gatcaacaca tactaattca aggaggtaag gatggcggaa
     4201 tgaaaccaac gaaattaatg aacagcatta ttgtactagc acttttgggg taacgttagc
     4261 tttttaattt aaaacccacg ttaactagga cattgctata ctaatgatac aacttaaaca
     4321 aaagaattag aggaaattat attgggaaaa atattatcta gaggattgct agctttatat
     4381 ttagtgacac taatctggtt agtgttattc aaattacaat acaatatttt atcagtattt
     4441 aattatcatc aaagaagtct taacttgact ccatttactg ctactgggaa tttcagagag
     4501 atgatagata atgttataat ctttattcca tttggcttgc ttttgaatgt caattttaaa
     4561 gaaatcggat ttttacctaa gtttgctttt gtactggttt taagtcttac ttttgaaata
     4621 attcaattta tcttcgctat tggagcgaca gacataacag atgtaattac aaatactgtt
     4681 ggaggctttc ttggactgaa attatatggt ttaagcaata agcatatgaa tcaaaaaaaa
     4741 ttagacagag ttattatttt tgtaggtata cttttgctcg tattattgct cgtttaccgt
     4801 acccatttaa gaataaatta cgtgtaagat gtctaaatca agcaatctga tctttcatac
     4861 acataaagat attgaatgaa ttggattaga tggaaaacgg gatgtgggga aactcgcccg
     4921 taggtgtgaa gtgaggggaa aaccggtgat aaagtaaaaa gcttacctaa cactatagta
     4981 acaaagaaag cccaattatc aattttagtg ctgaggaatt ggtctcttta ataaatttcc
     5041 ttaacgttgt aaatccgcat tttcctgacg gtacccccaa actaagattt catagataga
     5101 ttttctgata acttta
//
LOCUS       DAYYEF010000211         2772 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.137, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000211 DAYYEF010000000
VERSION     DAYYEF010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2772
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.137"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            111..194
                     /locus_tag="ACHA1B_003082"
     CDS             111..194
                     /locus_tag="ACHA1B_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0031556 - transcriptional attenuation by
                     ribosome [Evidence IEA];
                     GO_process: GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HFM8703739.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="ACHA1B_003083"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="ACHA1B_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011100845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HFM8703740.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(1319..2182)
                     /locus_tag="ACHA1B_003084"
     CDS             complement(1319..2182)
                     /locus_tag="ACHA1B_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0005524 - ATP binding [Evidence IEA];
                     GO_function: GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HFM8703741.1"
                     /translation="MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAL
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQSKGYETKIYVMAVPKIESYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLERELNRKVSGKEIQPTLERIEQKMVQNQHQETPEFKAIQQKMESLQLPTP
                     PIPKTPKLPGI"
     gene            complement(2184..2456)
                     /locus_tag="ACHA1B_003085"
     CDS             complement(2184..2456)
                     /locus_tag="ACHA1B_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HFM8703742.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEV
                     NLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYSKQILNKEKVA"
     gene            complement(2473..2682)
                     /locus_tag="ACHA1B_003086"
     CDS             complement(2473..2682)
                     /locus_tag="ACHA1B_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HFM8703743.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
BASE COUNT          851 a          488 c          443 g          990 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccaa aattttgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ccgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta tagatgtaat
      301 cacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 actcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggaatat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttgtaaatt
     1081 tggaaagtta cacgttacta aagggaatgt agataaatta ttaggtatag ggcacctcta
     1141 ataactacca attaattcac ctcaaaatga aattagaaaa aaacagcgaa atttttaaat
     1201 ctatttctta tcgatacaaa ttcctcgtag gcgctcggga ccccaacatg aggaaatgtt
     1261 tttataaaaa aagagtagtt accgtttttt ggtaactact cttttccttt tttaaggttt
     1321 aaatacctgg aagtttaggt gttttgggta ttggtggtgt aggtagctgc aagctttcca
     1381 ttttttgttg aattgcttta aattcagggg tttcttggtg ttgattttga accatttttt
     1441 gctctattct ctccaaagtc ggttgaattt ctttccctga tactttacga tttaattctc
     1501 tttctaaggt ctctttcgga ctaatggaag gcgtttctaa gcttgaatag agtttcactc
     1561 cttctctatt gtaaagcctt atatcgctaa ataagcccgt tttatgaagg gtttctaaat
     1621 tggtcggtaa gtttttgaca acaatatcat gcgcttgttt tggtgttgcc ctagctgtca
     1681 ttggatcatc tgcatacatg gtttcatatc gttcaatcgt tcctaagtat gattcaattt
     1741 tcggtactgc catgacgtat atttttgttt cataaccttt agattgaagc attgtggctg
     1801 tttgaatggg aacgtctgtt gttcgtcctg ttccttcaat cactaaatta tagccttgat
     1861 cgcttaaacg gctaataagt gcttctgtca tgcgattcga ataaggggta acgtgtttta
     1921 ctacgtcttt ttcatagagt ttcactaatt cgtcaaaatt tgggtgctgt tgtttaaagg
     1981 tatcattatc aatgacaata acattccctt gtgtttcttc aaaaattgct gatcgcaaac
     2041 tggttttccc tgaccctggt tgcccaccaa gtaaaaaagc ggttggcgat tcaaccgcta
     2101 gtctattttt agttagtcgt tcaacattct tttctaaacg atcttcaaat tgcttttcgg
     2161 tgaagtcagt aatattcgcc atgttaagcc actttctctt tattcaaaat ttgttttgaa
     2221 tattgattca ttgaccgcca atactcatga atagcttgta attcttcaaa tggttgttga
     2281 aataaatcaa cttcttgtgc cacttctaat tgatttaaaa gattcacttc tagtaaacga
     2341 gtatttttag tatctagttc atgattcaaa acataattta atacccgatt ataaacactt
     2401 gccgataact cattaatgat ttcaatttca aatgtttttt catacgtaac tgccatttca
     2461 ttttcactcc ttttaaagtt tgtcaggtaa atatttccgt atatattctt ctaaggcttg
     2521 atccataact tcttttacgt ttccgccatt ctttgctgtt tcgattttta tgatatggtg
     2581 caagtcggca cgaacacgaa ccgtcttatc ccccattata tctttttttg cgctgattgg
     2641 cgtatcattt cgttttgctt tctgtgcgcc taaatttccc acgatcgctc acttctttct
     2701 atttcttctt actatttatt ttatcatcac ctatcacaaa tcacaagtga tttgtgatta
     2761 atcacttgtg at
//
LOCUS       DAYYEF010000212         1400 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.160, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000212 DAYYEF010000000
VERSION     DAYYEF010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.160"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..459
                     /locus_tag="ACHA1B_003087"
     CDS             <1..459
                     /locus_tag="ACHA1B_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0000150 - DNA strand exchange activity
                     [Evidence IEA];
                     GO_function: GO:0003677 - DNA binding [Evidence IEA];
                     GO_process: GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HFM8703744.1"
                     /translation="TLFDSRFKTLQQNLQEDDIIYVTDLTRITRSTQDLFELIDNIRD
                     KKASLKSLKDTWLDLSEDNPYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFK
                     GRLKKYHKNHAGMNYAVKLYKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            673..1368
                     /gene="vanR-A"
                     /locus_tag="ACHA1B_003088"
     CDS             673..1368
                     /gene="vanR-A"
                     /locus_tag="ACHA1B_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_process: GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA];
                     GO_process: GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance response regulator
                     transcription factor VanR-A"
                     /protein_id="HFM8703745.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
BASE COUNT          519 a          236 c          274 g          371 t
ORIGIN      
        1 accttatttg atagtagatt taaaactttg caacagaacc tacaggaaga tgacatcatt
       61 tatgttacag acttaactcg aatcactcgt agtacacaag atctatttga attaatcgat
      121 aacatacgag ataaaaaggc aagtttaaaa tcactaaaag atacatggct tgatttatca
      181 gaagataatc catacagcca attcttaatt actgtaatgg ctggtgttaa ccaattagag
      241 cgagatctta ttcggatgag acaacgtgaa gggattgaat tggctaagaa agaaggaaag
      301 tttaaaggtc gattaaagaa gtatcataaa aatcacgcag gaatgaatta tgcggtaaag
      361 ctatataaag aaggaaatat gactgtaaat caaatttgtg aaattactaa tgtatctagg
      421 gcttcattat acaggaaatt atcagaagtg aataattagc cattctgtat tccgctaatg
      481 ggcaatattt ttaaagaaga aaaggaaact ataaaatatt aacagcctcc tagcgatgcc
      541 gaaaagccct ttgataaaaa aagaatcatc atcttaagaa attcttagtc atttattatg
      601 taaatgctta taaattcggc cctataatct gataaattat taagggcaaa cttatgtgaa
      661 agggtgataa ctatgagcga taaaatactt attgtggatg atgaacatga aattgccgat
      721 ttggttgaat tatacttaaa aaacgagaat tatacggttt tcaaatacta taccgccaaa
      781 gaagcattgg aatgtataga caagtctgag attgaccttg ccatattgga catcatgctt
      841 cccggcacaa gcggccttac tatctgtcaa aaaataaggg acaagcacac ctatccgatt
      901 atcatgctga ccgggaaaga tacagaggta gataaaatta cagggttaac aatcggcgcg
      961 gatgattata taacgaagcc ctttcgccca ctggagttaa ttgctcgggt aaaggcccag
     1021 ttgcgccgat acaaaaaatt cagtggagta aaggagcaga acgaaaatgt tatcgtccac
     1081 tccggccttg tcattaatgt taacacccat gagtgttatc tgaacgagaa gcagttatcc
     1141 cttactccca ccgagttttc aatactgcga atcctctgtg aaaacaaggg gaatgtggtt
     1201 agctccgagc tgctatttca tgagatatgg ggcgacgaat atttcagcaa gagcaacaac
     1261 accatcaccg tgcatatccg gcatttgcgc gaaaaaatga acgacaccat tgataatccg
     1321 aaatatataa aaacggtatg gggggttggt tataaaattg aaaaataaaa aaaacgacta
     1381 ttccaaacta gaacgaaaac
//
LOCUS       DAYYEF010000213         1236 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.172, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000213 DAYYEF010000000
VERSION     DAYYEF010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.172"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            27..1181
                     /gene="vanS"
                     /locus_tag="ACHA1B_003089"
     CDS             27..1181
                     /gene="vanS"
                     /locus_tag="ACHA1B_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin resistance histidine kinase VanS"
                     /protein_id="HFM8703746.1"
                     /translation="MVIKFKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT          403 a          226 c          274 g          333 t
ORIGIN      
        1 taaatatata aaaacggtat ggggggttgg ttataaaatt taaaaataaa aaaaacgact
       61 attccaaact agaacgaaaa ctttacatgt atatcgttgc aattgttgtg gtagcaattg
      121 tattcgtgtt gtatattcgt tcaatgatcc gagggaaact tggggattgg atcttaagta
      181 ttttggaaaa caaatatgac ttaaatcacc tggacgcgat gaaattatat caatattcca
      241 tacggaacaa tatagatatc tttatttatg tggcgattgt cattagtatt cttattctat
      301 gtcgcgtcat gctttcaaaa ttcgcaaaat actttgacga gataaatacc ggcattgatg
      361 tacttattca gaacgaagat aaacaaattg agctttctgc ggaaatggat gttatggaac
      421 aaaagctcaa cacattaaaa cggactctgg aaaagcgaga gcaggatgca aagctggccg
      481 aacaaagaaa aaatgacgtt gttatgtact tggcgcacga tattaaaacg ccccttacat
      541 ccattatcgg ttatttgagc ctgcttgacg aggctccaga catgccggta gatcaaaagg
      601 caaagtatgt gcatatcacg ttggacaaag cgtatcgact cgaacagcta atcgacgagt
      661 tttttgagat tacacggtat aacctacaaa cgataacgct aacaaaaacg cacatagacc
      721 tatactatat gctggtgcag atgaccgatg aattttatcc tcagctttcc gcacatggaa
      781 aacaggcggt tattcacgcc cccgaggatc tgaccgtgtc cggcgaccct gataaactcg
      841 cgagagtctt taacaacatt ttgaaaaacg ccgctgcata cagtgaggat aacagcatca
      901 ttgacattac cgcgggcctc tccggggatg tggtgtcaat cgaattcaag aacactggaa
      961 gcatcccaaa agataagcta gctgccatat ttgaaaagtt ctataggctg gacaatgctc
     1021 gttcttccga tacgggtggc gcgggacttg gattggcgat tgcaaaagaa attattgttc
     1081 agcatggagg gcagatttac gcggaaagca atgataacta tacgacgttt agggtagagc
     1141 ttccagcgat gccagacttg gttgataaaa ggaggtccta agagatgtat ataattttgg
     1201 ctctttgtca aatgatgttg gtaaagagaa atctta
//
LOCUS       DAYYEF010000214         1229 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.173, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000214 DAYYEF010000000
VERSION     DAYYEF010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.173"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            <1..1103
                     /locus_tag="ACHA1B_003090"
                     /note="aph(2'')-Ia"
     CDS             <1..1103
                     /locus_tag="ACHA1B_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HFM8703747.1"
                     /translation="TRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIE
                     DLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSV
                     AYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILG
                     YKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEE
                     YILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLT
                     GIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEY
                     YPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          529 a           95 c          201 g          404 t
ORIGIN      
        1 gtacaagata tattaaattg atttttgaat ttttgaaaaa agaaagaaat gctaatgcag
       61 ttattttaga ccctcataaa aataatccaa gagcaataag ggcataccaa aaatctggtt
      121 ttagaattat tgaagatttg ccagaacatg aattacacga gggcaaaaaa gaagattgtt
      181 atttaatgga atatagatat gatgataatg ccacaaatgt taaggcaatg aaatatttaa
      241 ttgagcatta ctttgataat ttcaaagtag atagtattga aataatcggt agtggttatg
      301 atagtgtggc atatttagtt aataatgaat acatttttaa aacaaaattt agtactaata
      361 agaaaaaagg ttatgcaaaa gaaaaagcaa tatataattt tttaaataca aatttagaaa
      421 ctaatgtaaa aattcctaat attgaatatt cgtatattag tgatgaatta tctatactag
      481 gttataaaga aattaaagga acttttttaa caccagaaat ttattctact atgtcagaag
      541 aagaacaaaa tttgttaaaa cgagatattg ccagtttttt aagacaaatg cacggtttag
      601 attatacaga tattagtgaa tgtactattg ataataaaca aaatgtatta gaagagtata
      661 tattgttgcg tgaaactatt tataatgatt taactgatat agaaaaagat tatatagaaa
      721 gttttatgga aagactaaat gcaacaacag tttttgaggg taaaaagtgt ttatgccata
      781 atgattttag ttgtaatcat ctattgttag atggcaataa tagattaact ggaataattg
      841 attttggaga ttctggaatt atagatgaat attgtgattt tatatactta cttgaagata
      901 gtgaagaaga aataggaaca aattttggag aagatatatt aagaatgtat ggaaatatag
      961 atattgagaa agcaaaagaa tatcaagata tagttgaaga atattatcct attgaaacta
     1021 ttgtttatgg aattaaaaat attaaacagg aatttatcga aaatggtaga aaagaaattt
     1081 ataaaaggac ttataaagat tgattatata atatatgaaa agctattata aaagacatta
     1141 gtattaaata gtttaaaaaa atgaaaaata ataaaggaag tgagtcaatt ccagactcct
     1201 gtgtaaaatg ctatacaatg tttttacca
//
LOCUS       DAYYEF010000215         1124 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.176, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000215 DAYYEF010000000
VERSION     DAYYEF010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1124
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.176"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            24..416
                     /locus_tag="ACHA1B_003091"
     CDS             24..416
                     /locus_tag="ACHA1B_003091"
                     /EC_number="2.3.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA];
                     GO_function: GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HFM8703748.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            417..>1124
                     /gene="aac(6')-Ie"
                     /locus_tag="ACHA1B_003092"
     CDS             417..>1124
                     /gene="aac(6')-Ie"
                     /locus_tag="ACHA1B_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HFM8703749.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKG"
BASE COUNT          456 a           88 c          195 g          385 t
ORIGIN      
        1 tatagttgaa gaatattatc ctattgaaac tattgtttat tgatgataat atggtttttg
       61 atattgataa tttaaaagga tttcttaatg ataccagttc atttgggttt atagctaaag
      121 aaaataataa aattatagga tttgcatatt gctatacact tttaagacct gatggaaaaa
      181 caatgtttta tttacactca ataggaatgt tacctaacta tcaagacaaa ggttatggtt
      241 caaaattatt atcttttatt aaggaatatt ctaaagagat tggttgttct gaaatgtttt
      301 taataactga taaaggtaat cctagagctt gccatgtata tgaaaaatta ggtggtaaaa
      361 atgattataa agatgaaata gtatatgtat atgattatga aaaaggtgat aaataaatga
      421 atatagttga aaatgaaata tgtataagaa ctttaataga tgatgatttt cctttgatgt
      481 taaaatggtt aactgatgaa agagtattag aattttatga tggtagagat aaaaaatata
      541 cattagaatc attaaaaaaa cattatacag agccttggga agatgaagtt tttagagtaa
      601 ttattgaata taacaatgtt cctattggat atggacaaat atataaaatg tatgatgagt
      661 tatatactga ttatcattat ccaaaaactg atgagatagt ctatggtatg gatcaattta
      721 taggagagcc aaattattgg agtaaaggaa ttggtacaag atatattaaa ttgatttttg
      781 aatttttgaa aaaagaaaga aatgctaatg cagttatttt agaccctcat aaaaataatc
      841 caagagcaat aagggcatac caaaaatctg gttttagaat tattgaagat ttgccagaac
      901 atgaattaca cgagggcaaa aaagaagatt gttatttaat ggaatataga tatgatgata
      961 atgccacaaa tgttaaggca atgaaatatt taattgagca ttactttgat aatttcaaag
     1021 tagatagtat tgaaataatc ggtagtggtt atgatagtgt ggcatattta gttaataatg
     1081 aatacatttt taaaacaaaa tttagtacta ataagaaaaa aggt
//
LOCUS       DAYYEF010000216          986 bp    DNA     linear   BCT 19-OCT-2024
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE3123
            SAMEA115706475-rid22594963.guided.185, whole genome shotgun
            sequence.
ACCESSION   DAYYEF010000216 DAYYEF010000000
VERSION     DAYYEF010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA115706475
            Sequence Read Archive: ERR13196211
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 986)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 986)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-AUG-2024) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-AUG-2024
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT002289935.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT002289935.1
            Genome Coverage       :: 329x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/18/2024 15:55:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Annotation Software revision      :: 2024-07-18.build7555
            Genes (total)                     :: 3,093
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 2,943
            CDSs (with protein)               :: 2,943
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 44 of 89
            Pseudo Genes (incomplete)         :: 50 of 89
            Pseudo Genes (internal stop)      :: 25 of 89
            Pseudo Genes (multiple problems)  :: 23 of 89
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..986
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA115706475-rid22594963.guided.185"
                     /isolate="VRE3123"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Denmark"
     gene            373..921
                     /gene="aac(6')"
                     /locus_tag="ACHA1B_003093"
     CDS             373..921
                     /gene="aac(6')"
                     /locus_tag="ACHA1B_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology.
                     GO_function: GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HFM8703750.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          348 a          143 c          194 g          301 t
ORIGIN      
        1 acgacaataa tgaatttttg ttcctcttag tatttctacc gattcccttt gcttttttgt
       61 aattatctaa aaattctaaa aattaagatt attatatgaa aacaggtttt atttgtcaat
      121 tcataattgg ttttttttaa agcaaaagat aatctatatc atgatgaaca aacagagttt
      181 tttcctccaa ttgatggctt tcctgatctt tcctattttg aataaagtgt ttctgtataa
      241 tttttttatt ttataagtaa gataaataat gaaagaatag agatactgat tggtagctaa
      301 agatttttga gcgagaacat ttcgtttttt caaaaggact gttagaataa gcaagaacaa
      361 gggggaagac gtatgataat cagtgaattt gaccgtaata atccagtatt gaaagatcag
      421 ctttctgatt tactgagact gacttggccg gaagaatatg gagacagctc ggcagaagaa
      481 gtagaagaaa tgatgaatcc agaacgaatc gcggtagcag cggtagacca agatgagtta
      541 gtaggattta ttggtgcaat ccctcaatac ggtatcacag gttgggaatt gcatccatta
      601 gttgtagaaa gctcccgacg aaagaaccaa ataggtactc gattagtcaa ttacttagaa
      661 aaagaagtag cttccagagg aggaatcacg atttatttag gtacggatga tttagaccat
      721 ggaacaacgt taagtcaaac ggacctgtat gagcatacat ttgataaagt ggcttccatc
      781 cagaaccttc gtgaacatcc gtatgaattc tatgaaaaat taggttataa aatcgtaggt
      841 gtcttaccaa atgcaaatgg ctgggacaaa ccggatattt ggatggcaaa aacgattatt
      901 cctcgaccaa attctcaata ataaaaagag gttgtgacag aagtaatcag cttcaagaaa
      961 taagaaggaa tttacgaaaa ttactt
//
